Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:81569
• Symbol:ACTL8
• Description:actin like 8

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTL8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
17823335	17823358	1	+	26472758	Jiyoye	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.04635827322491615	[234]	[182]	0	hSpCas9	negative selection	2110
17823137	17823160	1	-	26472758	Jiyoye	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.6702097873396675	[29]	[35]	5	hSpCas9	negative selection	2111
17823018	17823041	1	+	26472758	Jiyoye	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	1.6363093807213764	[60]	[142]	8	hSpCas9	negative selection	2112
17823215	17823238	1	+	26472758	Jiyoye	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.04316835475049019	[286]	[222]	0	hSpCas9	negative selection	2113
17823248	17823271	1	-	26472758	Jiyoye	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.6594490925018831	[156]	[186]	5	hSpCas9	negative selection	2114
17823182	17823205	1	-	26472758	Jiyoye	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	2.3687012336912376	[18]	[73]	9	hSpCas9	negative selection	2115
17823269	17823292	1	+	26472758	Jiyoye	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.39096515432461454	[178]	[176]	3	hSpCas9	negative selection	2116
17823314	17823337	1	+	26472758	Jiyoye	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	5.799492804284633	[0]	[41]	9	hSpCas9	negative selection	2117
17823295	17823318	1	-	26472758	Jiyoye	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.3482816924523049	[74]	[71]	2	hSpCas9	negative selection	2118
17823114	17823137	1	+	26472758	Jiyoye	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	0.7755627874858959	[54]	[70]	5	hSpCas9	negative selection	2119
17823335	17823358	1	+	26472758	KBM7	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.14076529522514536	[1000,550]	[367,413]	1	hSpCas9	negative selection	193228
17823137	17823160	1	-	26472758	KBM7	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.07557605987772975	[233,174]	[131,71]	0	hSpCas9	negative selection	193229
17823018	17823041	1	+	26472758	KBM7	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.6919030614423174	[240,285]	[280,132]	7	hSpCas9	negative selection	193230
17823215	17823238	1	+	26472758	KBM7	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.33103493585111177	[1264,980]	[708,613]	3	hSpCas9	negative selection	193231
17823248	17823271	1	-	26472758	KBM7	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.6057857770936427	[550,503]	[602,175]	6	hSpCas9	negative selection	193232
17823182	17823205	1	-	26472758	KBM7	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.7458532887383796	[235,110]	[180,88]	7	hSpCas9	negative selection	193233
17823269	17823292	1	+	26472758	KBM7	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.7918868294889432	[549,582]	[468,460]	8	hSpCas9	negative selection	193234
17823314	17823337	1	+	26472758	KBM7	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	0.6919199683331425	[35,97]	[80,28]	7	hSpCas9	negative selection	193235
17823295	17823318	1	-	26472758	KBM7	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.41477163403449696	[401,554]	[281,327]	4	hSpCas9	negative selection	193236
17823114	17823137	1	+	26472758	KBM7	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	0.10384254435135576	[316,370]	[174,176]	1	hSpCas9	negative selection	193237
17823335	17823358	1	+	26472758	Raji	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.47935231276055734	[339]	[109]	4	hSpCas9	negative selection	384346
17823137	17823160	1	-	26472758	Raji	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.9605421470443285	[92]	[41]	8	hSpCas9	negative selection	384347
17823018	17823041	1	+	26472758	Raji	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	-0.4134486279278411	[131]	[22]	-3	hSpCas9	negative selection	384348
17823215	17823238	1	+	26472758	Raji	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.17989603515796726	[581]	[152]	1	hSpCas9	negative selection	384349
17823248	17823271	1	-	26472758	Raji	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	-0.35426932318037596	[324]	[58]	-3	hSpCas9	negative selection	384350
17823182	17823205	1	-	26472758	Raji	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.33479403147667197	[81]	[23]	3	hSpCas9	negative selection	384351
17823269	17823292	1	+	26472758	Raji	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	-1.5638113629916357	[292]	[22]	-8	hSpCas9	negative selection	384352
17823314	17823337	1	+	26472758	Raji	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	0.9080747271501928	[61]	[26]	8	hSpCas9	negative selection	384353
17823295	17823318	1	-	26472758	Raji	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.07635663975297502	[375]	[91]	0	hSpCas9	negative selection	384354
17823114	17823137	1	+	26472758	Raji	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	-0.7670855825425416	[131]	[17]	-5	hSpCas9	negative selection	384355
17823335	17823358	1	+	26472758	K562	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.07287544782575173	[668]	[593]	0	hSpCas9	negative selection	575464
17823137	17823160	1	-	26472758	K562	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.958574438924567	[152]	[250]	7	hSpCas9	negative selection	575465
17823018	17823041	1	+	26472758	K562	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.10638857677400115	[273]	[248]	0	hSpCas9	negative selection	575466
17823215	17823238	1	+	26472758	K562	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	-0.6428895039792436	[996]	[538]	-4	hSpCas9	negative selection	575467
17823248	17823271	1	-	26472758	K562	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.6814825332752895	[519]	[703]	5	hSpCas9	negative selection	575468
17823182	17823205	1	-	26472758	K562	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.5187811393017534	[147]	[178]	4	hSpCas9	negative selection	575469
17823269	17823292	1	+	26472758	K562	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.31406915923393924	[464]	[487]	2	hSpCas9	negative selection	575470
17823314	17823337	1	+	26472758	K562	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	-0.5331888509971048	[59]	[34]	-3	hSpCas9	negative selection	575471
17823295	17823318	1	-	26472758	K562	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-0.5708139232970225	[504]	[286]	-4	hSpCas9	negative selection	575472
17823114	17823137	1	+	26472758	K562	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	-0.09086775007593428	[216]	[171]	0	hSpCas9	negative selection	575473
17823164	17823187	1	-	26627737	DLD1	viability	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	-0.32457396215142875	[63]	[8,15,21]	-3	hSpCas9	negative selection	767885
17823216	17823239	1	+	26627737	DLD1	viability	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	0.3022055146153443	[216]	[115,122,22]	3	hSpCas9	negative selection	767886
17823330	17823353	1	-	26627737	DLD1	viability	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	-0.32094262469636514	[204]	[47,36,65]	-3	hSpCas9	negative selection	767887
17825841	17825864	1	-	26627737	DLD1	viability	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-1.5503478322146365	[843]	[190,56,29]	-8	hSpCas9	negative selection	767888
17825884	17825907	1	+	26627737	DLD1	viability	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	-0.07903398508636372	[1442]	[634,340,317]	-1	hSpCas9	negative selection	767889
17826186	17826209	1	+	26627737	DLD1	viability	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	-0.35750637861375983	[537]	[198,79,114]	-4	hSpCas9	negative selection	767890
17823164	17823187	1	-	26627737	GBM cells	viability after 5 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	-1.3905927423092996	[21]	[4,3]	-9	hSpCas9	negative selection	850200
17823216	17823239	1	+	26627737	GBM cells	viability after 5 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	0.3919538861658027	[134]	[78,110]	6	hSpCas9	negative selection	850201
17823330	17823353	1	-	26627737	GBM cells	viability after 5 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	0.31813917112796286	[85]	[47,66]	5	hSpCas9	negative selection	850202
17825841	17825864	1	-	26627737	GBM cells	viability after 5 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.6910020402899794	[189]	[151,176]	8	hSpCas9	negative selection	850203
17825884	17825907	1	+	26627737	GBM cells	viability after 5 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.0020073678497893876	[647]	[366,328]	0	hSpCas9	negative selection	850204
17826186	17826209	1	+	26627737	GBM cells	viability after 5 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.47682161807289125	[204]	[190,114]	7	hSpCas9	negative selection	850205
17823164	17823187	1	-	26627737	GBM cells	viability after 13 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	-0.43477090060355517	[21]	[15,2]	-5	hSpCas9	negative selection	932515
17823216	17823239	1	+	26627737	GBM cells	viability after 13 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	0.0042380546476232794	[134]	[105,46]	0	hSpCas9	negative selection	932516
17823330	17823353	1	-	26627737	GBM cells	viability after 13 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	0.9466302698357136	[85]	[95,84]	9	hSpCas9	negative selection	932517
17825841	17825864	1	-	26627737	GBM cells	viability after 13 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.8945002094411247	[189]	[232,157]	9	hSpCas9	negative selection	932518
17825884	17825907	1	+	26627737	GBM cells	viability after 13 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	-0.24822183943219245	[647]	[327,269]	-3	hSpCas9	negative selection	932519
17826186	17826209	1	+	26627737	GBM cells	viability after 13 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.640375096396604	[204]	[238,119]	7	hSpCas9	negative selection	932520
17823164	17823187	1	-	26627737	GBM cells	viability after 21 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	0.8604248185354781	[21]	[16,25]	8	hSpCas9	negative selection	1014830
17823216	17823239	1	+	26627737	GBM cells	viability after 21 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	0.1730392813609254	[134]	[89,75]	1	hSpCas9	negative selection	1014831
17823330	17823353	1	-	26627737	GBM cells	viability after 21 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	0.8121068917632018	[85]	[92,71]	7	hSpCas9	negative selection	1014832
17825841	17825864	1	-	26627737	GBM cells	viability after 21 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.054688312174308085	[189]	[113,100]	0	hSpCas9	negative selection	1014833
17825884	17825907	1	+	26627737	GBM cells	viability after 21 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	-0.06415397244628207	[647]	[342,330]	0	hSpCas9	negative selection	1014834
17826186	17826209	1	+	26627737	GBM cells	viability after 21 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.5802278399145449	[204]	[177,155]	6	hSpCas9	negative selection	1014835
17823164	17823187	1	-	26627737	RPE1	viability after 9 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	1.4943662040053463	[39]	[50,14]	8	hSpCas9	negative selection	1097145
17823216	17823239	1	+	26627737	RPE1	viability after 9 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.602317591208075	[395]	[99,57]	-4	hSpCas9	negative selection	1097146
17823330	17823353	1	-	26627737	RPE1	viability after 9 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	1.7120156389867625	[140]	[203,67]	8	hSpCas9	negative selection	1097147
17825841	17825864	1	-	26627737	RPE1	viability after 9 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-1.4933972221169003	[788]	[109,58]	-8	hSpCas9	negative selection	1097148
17825884	17825907	1	+	26627737	RPE1	viability after 9 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	-0.23787005850186405	[2711]	[774,648]	-2	hSpCas9	negative selection	1097149
17826186	17826209	1	+	26627737	RPE1	viability after 9 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.9508027622609057	[577]	[237,493]	6	hSpCas9	negative selection	1097150
17823164	17823187	1	-	26627737	RPE1	viability after 12 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	1.824278666912071	[39]	[39,35]	8	hSpCas9	negative selection	1179460
17823216	17823239	1	+	26627737	RPE1	viability after 12 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-1.3389662692944255	[395]	[60,21]	-7	hSpCas9	negative selection	1179461
17823330	17823353	1	-	26627737	RPE1	viability after 12 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	1.6311462743084337	[140]	[162,68]	8	hSpCas9	negative selection	1179462
17825841	17825864	1	-	26627737	RPE1	viability after 12 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-1.0099957491939517	[788]	[113,95]	-6	hSpCas9	negative selection	1179463
17825884	17825907	1	+	26627737	RPE1	viability after 12 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.027910934395006803	[2711]	[754,729]	0	hSpCas9	negative selection	1179464
17826186	17826209	1	+	26627737	RPE1	viability after 12 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.7682317188450881	[577]	[178,354]	5	hSpCas9	negative selection	1179465
17823164	17823187	1	-	26627737	RPE1	viability after 15 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	1.5740712400066834	[39]	[22,43]	8	hSpCas9	negative selection	1261775
17823216	17823239	1	+	26627737	RPE1	viability after 15 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-1.2714704342319325	[395]	[79,13]	-7	hSpCas9	negative selection	1261776
17823330	17823353	1	-	26627737	RPE1	viability after 15 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	1.4056770130193648	[140]	[123,87]	7	hSpCas9	negative selection	1261777
17825841	17825864	1	-	26627737	RPE1	viability after 15 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-1.0228515003390788	[788]	[174,46]	-6	hSpCas9	negative selection	1261778
17825884	17825907	1	+	26627737	RPE1	viability after 15 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.12256420871245233	[2711]	[908,763]	0	hSpCas9	negative selection	1261779
17826186	17826209	1	+	26627737	RPE1	viability after 15 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	1.1431844587691877	[577]	[353,367]	6	hSpCas9	negative selection	1261780
17823164	17823187	1	-	26627737	RPE1	viability after 18 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	2.400390250050962	[39]	[12,103]	9	hSpCas9	negative selection	1344090
17823216	17823239	1	+	26627737	RPE1	viability after 18 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-1.0305963784943564	[395]	[75,26]	-6	hSpCas9	negative selection	1344091
17823330	17823353	1	-	26627737	RPE1	viability after 18 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	1.8501937752646174	[140]	[171,99]	8	hSpCas9	negative selection	1344092
17825841	17825864	1	-	26627737	RPE1	viability after 18 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-1.1483251259256801	[788]	[126,62]	-6	hSpCas9	negative selection	1344093
17825884	17825907	1	+	26627737	RPE1	viability after 18 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.2220424846628728	[2711]	[799,910]	1	hSpCas9	negative selection	1344094
17826186	17826209	1	+	26627737	RPE1	viability after 18 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	1.399084052550337	[577]	[407,414]	7	hSpCas9	negative selection	1344095
17823164	17823187	1	-	26627737	HeLa	viability after 8 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	6.33099157833256	[0]	[1,18,73]	9	hSpCas9	negative selection	1426405
17823216	17823239	1	+	26627737	HeLa	viability after 8 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-1.0520505613526843	[366]	[110,12,111]	-8	hSpCas9	negative selection	1426406
17823330	17823353	1	-	26627737	HeLa	viability after 8 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	0.48820675323228546	[167]	[153,77,87]	4	hSpCas9	negative selection	1426407
17825841	17825864	1	-	26627737	HeLa	viability after 8 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-0.43948926445316144	[449]	[71,226,119]	-4	hSpCas9	negative selection	1426408
17825884	17825907	1	+	26627737	HeLa	viability after 8 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	-0.22092122617677434	[1414]	[695,533,400]	-2	hSpCas9	negative selection	1426409
17826186	17826209	1	+	26627737	HeLa	viability after 8 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	-0.14242588019874555	[333]	[215,86,111]	-1	hSpCas9	negative selection	1426410
17823164	17823187	1	-	26627737	HeLa	viability after 12 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	6.398778120749644	[0]	[40,13,51]	9	hSpCas9	negative selection	1508720
17823216	17823239	1	+	26627737	HeLa	viability after 12 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.011485784926936027	[366]	[153,107,193]	0	hSpCas9	negative selection	1508721
17823330	17823353	1	-	26627737	HeLa	viability after 12 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	-0.13939755993613834	[167]	[11,49,126]	-1	hSpCas9	negative selection	1508722
17825841	17825864	1	-	26627737	HeLa	viability after 12 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-0.6425408201612888	[449]	[136,155,60]	-5	hSpCas9	negative selection	1508723
17825884	17825907	1	+	26627737	HeLa	viability after 12 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.3937066551109316	[1414]	[1173,612,545]	3	hSpCas9	negative selection	1508724
17826186	17826209	1	+	26627737	HeLa	viability after 12 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	-0.1919420731539496	[333]	[226,116,21]	-2	hSpCas9	negative selection	1508725
17823164	17823187	1	-	26627737	HeLa	viability after 15 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	5.697649183519875	[0]	[0,0,64]	9	hSpCas9	negative selection	1591035
17823216	17823239	1	+	26627737	HeLa	viability after 15 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.07165398283780497	[366]	[253,89,75]	0	hSpCas9	negative selection	1591036
17823330	17823353	1	-	26627737	HeLa	viability after 15 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	0.6050264769749694	[167]	[17,120,179]	5	hSpCas9	negative selection	1591037
17825841	17825864	1	-	26627737	HeLa	viability after 15 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-0.26128555323647296	[449]	[186,191,72]	-2	hSpCas9	negative selection	1591038
17825884	17825907	1	+	26627737	HeLa	viability after 15 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.370564409074837	[1414]	[566,544,1155]	3	hSpCas9	negative selection	1591039
17826186	17826209	1	+	26627737	HeLa	viability after 15 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	-0.03717593683993517	[333]	[143,185,61]	0	hSpCas9	negative selection	1591040
17823164	17823187	1	-	26627737	HeLa	viability after 18 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	5.713936698347078	[0]	[0,0,64]	9	hSpCas9	negative selection	1673350
17823216	17823239	1	+	26627737	HeLa	viability after 18 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.08340677915952968	[366]	[166,75,75]	0	hSpCas9	negative selection	1673351
17823330	17823353	1	-	26627737	HeLa	viability after 18 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	0.6400312927236732	[167]	[13,103,179]	5	hSpCas9	negative selection	1673352
17825841	17825864	1	-	26627737	HeLa	viability after 18 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-0.3019122895110836	[449]	[121,152,72]	-3	hSpCas9	negative selection	1673353
17825884	17825907	1	+	26627737	HeLa	viability after 18 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.37448503270761346	[1414]	[374,462,1155]	3	hSpCas9	negative selection	1673354
17826186	17826209	1	+	26627737	HeLa	viability after 18 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.027244210174411226	[333]	[105,156,61]	0	hSpCas9	negative selection	1673355
17823164	17823187	1	-	26627737	HCT116	viability after 6 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	2.436268987373535	[29]	[69,0]	9	hSpCas9	negative selection	1755665
17823216	17823239	1	+	26627737	HCT116	viability after 6 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.9960321656325409	[392]	[39,25]	-5	hSpCas9	negative selection	1755666
17823330	17823353	1	-	26627737	HCT116	viability after 6 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	-0.9178750018591795	[421]	[18,43]	-5	hSpCas9	negative selection	1755667
17825841	17825864	1	-	26627737	HCT116	viability after 6 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.4474090298628729	[639]	[171,117]	2	hSpCas9	negative selection	1755668
17825884	17825907	1	+	26627737	HCT116	viability after 6 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.9962383202777538	[2038]	[777,562]	5	hSpCas9	negative selection	1755669
17826186	17826209	1	+	26627737	HCT116	viability after 6 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.7462598226246652	[214]	[144,7]	4	hSpCas9	negative selection	1755670
17823164	17823187	1	-	26627737	HCT116	viability after 8 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	2.0562442011963027	[27]	[99,16,75]	9	hSpCas9	negative selection	1837980
17823216	17823239	1	+	26627737	HCT116	viability after 8 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	0.011144978622313395	[212]	[129,102,121]	0	hSpCas9	negative selection	1837981
17823330	17823353	1	-	26627737	HCT116	viability after 8 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	-1.5483520550494563	[385]	[47,119,49]	-9	hSpCas9	negative selection	1837982
17825841	17825864	1	-	26627737	HCT116	viability after 8 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.31385522307701097	[131]	[202,41,28]	3	hSpCas9	negative selection	1837983
17825884	17825907	1	+	26627737	HCT116	viability after 8 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.6142052959644615	[855]	[928,459,779]	6	hSpCas9	negative selection	1837984
17826186	17826209	1	+	26627737	HCT116	viability after 8 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.7680448011522772	[194]	[113,273,159]	7	hSpCas9	negative selection	1837985
17823164	17823187	1	-	26627737	HCT116	viability after 9 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	-0.0718027974852058	[29]	[15,0]	0	hSpCas9	negative selection	1920295
17823216	17823239	1	+	26627737	HCT116	viability after 9 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-1.2637450930604262	[392]	[36,48]	-7	hSpCas9	negative selection	1920296
17823330	17823353	1	-	26627737	HCT116	viability after 9 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	-1.3073152947590474	[421]	[49,41]	-7	hSpCas9	negative selection	1920297
17825841	17825864	1	-	26627737	HCT116	viability after 9 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	1.0307779077983736	[639]	[361,338]	7	hSpCas9	negative selection	1920298
17825884	17825907	1	+	26627737	HCT116	viability after 9 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.2850907083171246	[2038]	[897,477]	2	hSpCas9	negative selection	1920299
17826186	17826209	1	+	26627737	HCT116	viability after 9 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	1.678521179536019	[214]	[309,83]	8	hSpCas9	negative selection	1920300
17823164	17823187	1	-	26627737	HCT116	viability after 12 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	1.1119557994979141	[27]	[27,0,65]	8	hSpCas9	negative selection	2002610
17823216	17823239	1	+	26627737	HCT116	viability after 12 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	0.04868737674540774	[212]	[134,88,120]	0	hSpCas9	negative selection	2002611
17823330	17823353	1	-	26627737	HCT116	viability after 12 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	-1.6777159156602086	[385]	[82,83,21]	-9	hSpCas9	negative selection	2002612
17825841	17825864	1	-	26627737	HCT116	viability after 12 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.6566912099549357	[131]	[157,34,128]	6	hSpCas9	negative selection	2002613
17825884	17825907	1	+	26627737	HCT116	viability after 12 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.44408670795803307	[855]	[587,524,722]	4	hSpCas9	negative selection	2002614
17826186	17826209	1	+	26627737	HCT116	viability after 12 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.8743351119904637	[194]	[139,196,230]	7	hSpCas9	negative selection	2002615
17823164	17823187	1	-	26627737	HCT116	viability after 15 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	1.0274937687783101	[27]	[17,0,76]	8	hSpCas9	negative selection	2084925
17823216	17823239	1	+	26627737	HCT116	viability after 15 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.34615438983425106	[212]	[122,76,91]	-4	hSpCas9	negative selection	2084926
17823330	17823353	1	-	26627737	HCT116	viability after 15 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	-1.7020133296079643	[385]	[105,33,68]	-9	hSpCas9	negative selection	2084927
17825841	17825864	1	-	26627737	HCT116	viability after 15 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.5185259687580044	[131]	[177,111,44]	5	hSpCas9	negative selection	2084928
17825884	17825907	1	+	26627737	HCT116	viability after 15 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.7618350955909317	[855]	[921,715,872]	6	hSpCas9	negative selection	2084929
17826186	17826209	1	+	26627737	HCT116	viability after 15 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.6724888976417466	[194]	[160,165,205]	6	hSpCas9	negative selection	2084930
17823164	17823187	1	-	26627737	HCT116	viability after 18 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	1.8288131430507162	[27]	[88,24,30]	9	hSpCas9	negative selection	2167240
17823216	17823239	1	+	26627737	HCT116	viability after 18 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.29934348735239724	[212]	[117,9,129]	-3	hSpCas9	negative selection	2167241
17823330	17823353	1	-	26627737	HCT116	viability after 18 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	-1.9086434513161228	[385]	[67,25,56]	-9	hSpCas9	negative selection	2167242
17825841	17825864	1	-	26627737	HCT116	viability after 18 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.5567221349227532	[131]	[149,75,54]	5	hSpCas9	negative selection	2167243
17825884	17825907	1	+	26627737	HCT116	viability after 18 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.6184633517882103	[855]	[759,412,752]	5	hSpCas9	negative selection	2167244
17826186	17826209	1	+	26627737	HCT116	viability after 18 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.7715118380618379	[194]	[177,134,171]	6	hSpCas9	negative selection	2167245
17825960	17825983	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGACTCTTGAGGAGATAGGCGG	ACTL8	ENSG00000117148	-0.33061311743673777	[4,4]	[3,1]	-5	hSpCas9	positive selection	2968718
17823248	17823271	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	-0.5338467008284853	[1,1]	[0,1]	-7	hSpCas9	positive selection	2968719
17823295	17823318	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-0.2585018339474786	[2,2]	[3,0]	-4	hSpCas9	positive selection	2968720
17823261	17823284	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGTTGGAGAACCACAGACGGG	ACTL8	ENSG00000117148	0.48817042171066266	[3,3]	[2,5]	8	hSpCas9	positive selection	2968721
17825960	17825983	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGACTCTTGAGGAGATAGGCGG	ACTL8	ENSG00000117148	0.7489477698124067	[4,4]	[4,6]	9	hSpCas9	positive selection	3036576
17823248	17823271	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	1.6709305314085243	[1,1]	[1,7]	9	hSpCas9	positive selection	3036577
17823295	17823318	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.7295806523996878	[2,2]	[2,4]	9	hSpCas9	positive selection	3036578
17823261	17823284	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGTTGGAGAACCACAGACGGG	ACTL8	ENSG00000117148	-0.24403351177852572	[3,3]	[2,1]	-4	hSpCas9	positive selection	3036579
17826235	17826258		-	24336571	A375	resistance to PLX after 7 days	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.4093643152913106	[12,12]	[9,8]	-9	hSpCas9	positive selection	3159834
17823193	17823216		-	24336571	A375	resistance to PLX after 7 days	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	-0.09285509042427453	[7,6]	[6,7]	-3	hSpCas9	positive selection	3159845
17825921	17825944		-	24336571	A375	resistance to PLX after 7 days	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.10414780860734474	[18,23]	[23,20]	3	hSpCas9	positive selection	3159855
17823007	17823030		-	24336571	A375	resistance to PLX after 7 days	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.15021921409512004	[13,14]	[15,14]	5	hSpCas9	positive selection	3159866
17826051	17826074		+	24336571	A375	resistance to PLX after 7 days	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.07222888086321821	[20,23]	[22,22]	2	hSpCas9	positive selection	3159877
17823332	17823355		+	24336571	A375	resistance to PLX after 7 days	TGCGGACCGAAAGAAGATGCTGG	ACTL8	ENSG00000117148	-0.27726340017718776	[13,15]	[11,11]	-7	hSpCas9	positive selection	3159884
17826235	17826258		-	24336571	A375	resistance to PLX after 14 days	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.04606972109117141	[13,9]	[5,4]	0	hSpCas9	positive selection	3217627
17823193	17823216		-	24336571	A375	resistance to PLX after 14 days	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.05759837838092563	[5,10]	[3,3]	0	hSpCas9	positive selection	3217638
17825921	17825944		-	24336571	A375	resistance to PLX after 14 days	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	-0.8733703860148642	[21,25]	[5,5]	-8	hSpCas9	positive selection	3217648
17823007	17823030		-	24336571	A375	resistance to PLX after 14 days	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.8466324901669803	[18,14]	[14,12]	7	hSpCas9	positive selection	3217659
17826051	17826074		+	24336571	A375	resistance to PLX after 14 days	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.603378113725168	[18,20]	[13,13]	5	hSpCas9	positive selection	3217670
17823332	17823355		+	24336571	A375	resistance to PLX after 14 days	TGCGGACCGAAAGAAGATGCTGG	ACTL8	ENSG00000117148	0.10871598633894392	[18,15]	[6,10]	1	hSpCas9	positive selection	3217677
17826235	17826258		-	24336571	A375	viability after 7 days	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.2827938508418152	[10]	[12,12]	4	hSpCas9	negative selection	3275420
17823193	17823216		-	24336571	A375	viability after 7 days	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.22579058708524902	[6]	[7,6]	3	hSpCas9	negative selection	3275431
17825921	17825944		-	24336571	A375	viability after 7 days	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	-0.04827659763566361	[22]	[18,23]	0	hSpCas9	negative selection	3275441
17823007	17823030		-	24336571	A375	viability after 7 days	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.23035440423143755	[12]	[13,14]	3	hSpCas9	negative selection	3275452
17826051	17826074		+	24336571	A375	viability after 7 days	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.38977965525232655	[17]	[20,23]	6	hSpCas9	negative selection	3275463
17823332	17823355		+	24336571	A375	viability after 7 days	TGCGGACCGAAAGAAGATGCTGG	ACTL8	ENSG00000117148	0.24062916040747556	[12]	[13,15]	3	hSpCas9	negative selection	3275470
17826235	17826258		-	24336571	A375	viability after 14 days	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.1978206941827786	[10]	[13,9]	2	hSpCas9	negative selection	3333213
17823193	17823216		-	24336571	A375	viability after 14 days	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.28839194280300073	[6]	[5,10]	4	hSpCas9	negative selection	3333224
17825921	17825944		-	24336571	A375	viability after 14 days	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.13855523715164253	[22]	[21,25]	1	hSpCas9	negative selection	3333234
17823007	17823030		-	24336571	A375	viability after 14 days	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.4848409791483146	[12]	[18,14]	6	hSpCas9	negative selection	3333245
17826051	17826074		+	24336571	A375	viability after 14 days	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.27366567256939395	[17]	[18,20]	3	hSpCas9	negative selection	3333256
17823332	17823355		+	24336571	A375	viability after 14 days	TGCGGACCGAAAGAAGATGCTGG	ACTL8	ENSG00000117148	0.48548695250383067	[12]	[18,15]	6	hSpCas9	negative selection	3333263
17825921	17825944	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	2.328290256599543	[24,35]	[0,0]	8	hSpCas9	positive selection	3335416
17823007	17823030	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.5632471922056914	[109,96]	[0,0]	3	hSpCas9	positive selection	3335417
17826051	17826074	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	4.560517743751612	[3,8]	[0,0]	9	hSpCas9	positive selection	3335418
17823139	17823162	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	1.2349583984173806	[64,64]	[0,0]	5	hSpCas9	positive selection	3354666
17826235	17826258	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	5.3012695590334316	[96,96]	[24,24]	9	hSpCas9	positive selection	3354667
17823193	17823216	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	1.0478728458168853	[73,73]	[0,0]	5	hSpCas9	positive selection	3354668
17825960	17825983	1	-	26780180	HT29	viability (Avana library 4 designs)	GAGACTCTTGAGGAGATAGGCGG	ACTL8	ENSG00000117148	0.887413559955796	[]	[]	3	hSpCas9	negative selection	3404666
17823248	17823271	1	-	26780180	HT29	viability (Avana library 4 designs)	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	1.03150293580984	[]	[]	4	hSpCas9	negative selection	3404667
17823295	17823318	1	-	26780180	HT29	viability (Avana library 4 designs)	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.849652059205494	[]	[]	3	hSpCas9	negative selection	3404668
17823260	17823283	1	+	26780180	HT29	viability (Avana library 4 designs)	TGTGTTGGAGAACCACAGACGGG	ACTL8	ENSG00000117148	1.62803573467094	[]	[]	6	hSpCas9	negative selection	3404669
17823248	17823271	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	-4.82193259087849	[]	[]	-5	hSpCas9	negative selection	3476315
17823295	17823318	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-4.04116702117246	[]	[]	-4	hSpCas9	negative selection	3476316
17825960	17825983	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGACTCTTGAGGAGATAGGCGG	ACTL8	ENSG00000117148	3.40606763203251	[]	[]	5	hSpCas9	negative selection	3476317
17823260	17823283	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGTTGGAGAACCACAGACGGG	ACTL8	ENSG00000117148	4.65000980128955	[]	[]	7	hSpCas9	negative selection	3476318
17823193	17823216	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTTAGCTACCCCATCGAGCGG	ACTL8	ENSG00000117148	-0.552280556369835	[]	[]	0	hSpCas9	negative selection	3476319
17823195	17823218	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	1.43030674219824	[]	[]	2	hSpCas9	negative selection	3476320
17823248	17823271	1	-	26780180	A375	viability (Avana lentiGuide)	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	14.6621582399768	[]	[]	8	hSpCas9	negative selection	3584974
17823295	17823318	1	-	26780180	A375	viability (Avana lentiGuide)	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-2.24224053683909	[]	[]	-4	hSpCas9	negative selection	3584975
17825960	17825983	1	-	26780180	A375	viability (Avana lentiGuide)	GAGACTCTTGAGGAGATAGGCGG	ACTL8	ENSG00000117148	-0.134766387059596	[]	[]	0	hSpCas9	negative selection	3584976
17823260	17823283	1	+	26780180	A375	viability (Avana lentiGuide)	TGTGTTGGAGAACCACAGACGGG	ACTL8	ENSG00000117148	4.57476668301066	[]	[]	4	hSpCas9	negative selection	3584977
17823193	17823216	1	+	26780180	A375	viability (Avana lentiGuide)	CCTTTAGCTACCCCATCGAGCGG	ACTL8	ENSG00000117148	8.11802389838166	[]	[]	6	hSpCas9	negative selection	3584978
17823195	17823218	1	+	26780180	A375	viability (Avana lentiGuide)	TTTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	2.64785925644119	[]	[]	3	hSpCas9	negative selection	3584979
17823248	17823271	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	-0.7380087890501228	[1]	[0,0]	-8	hSpCas9	positive selection	3693633
17823295	17823318	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-0.045031422129003365	[5]	[5,4]	-1	hSpCas9	positive selection	3693634
17825960	17825983	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGACTCTTGAGGAGATAGGCGG	ACTL8	ENSG00000117148	0.24257092079998369	[5]	[6,6]	7	hSpCas9	positive selection	3693635
17823260	17823283	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGTTGGAGAACCACAGACGGG	ACTL8	ENSG00000117148	0.15025385330690286	[4]	[5,5]	4	hSpCas9	positive selection	3693636
17823193	17823216	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTTAGCTACCCCATCGAGCGG	ACTL8	ENSG00000117148	0.10521432797108596	[4]	[4,4]	2	hSpCas9	positive selection	3693637
17823195	17823218	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.05654592000656364	[4]	[4,4]	1	hSpCas9	positive selection	3693638
17823248	17823271	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	-0.2998637661583803	[2]	[0,1]	-4	hSpCas9	positive selection	3802240
17823295	17823318	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-1.0762477694225947	[4]	[1,1]	-8	hSpCas9	positive selection	3802241
17825960	17825983	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGACTCTTGAGGAGATAGGCGG	ACTL8	ENSG00000117148	-0.11247203286211413	[6]	[3,5]	-1	hSpCas9	positive selection	3802242
17823260	17823283	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGTTGGAGAACCACAGACGGG	ACTL8	ENSG00000117148	0.2267546013682748	[5]	[5,5]	6	hSpCas9	positive selection	3802243
17823193	17823216	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTTAGCTACCCCATCGAGCGG	ACTL8	ENSG00000117148	-0.3067959763267125	[5]	[4,2]	-4	hSpCas9	positive selection	3802244
17823195	17823218	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.27993553723465825	[4]	[3,4]	7	hSpCas9	positive selection	3802245
17826235	17826258	1	-	26780180	A375	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	1.33231100668695	[]	[]	7	hSpCas9	negative selection	3910847
17823139	17823162	1	-	26780180	A375	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.354896846055065	[]	[]	0	hSpCas9	negative selection	3910848
17823193	17823216	1	-	26780180	A375	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.589933067020216	[]	[]	1	hSpCas9	negative selection	3910849
17825921	17825944	1	-	26780180	A375	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.654772526130674	[]	[]	2	hSpCas9	negative selection	3910850
17823007	17823030	1	-	26780180	A375	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.662708426751244	[]	[]	2	hSpCas9	negative selection	3910851
17826051	17826074	1	+	26780180	A375	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.233100948412086	[]	[]	0	hSpCas9	negative selection	3910852
17826235	17826258	1	-	26780180	HT29	viability (GeCKOv2 library)	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.934382193484204	[]	[]	4	hSpCas9	negative selection	4018813
17823139	17823162	1	-	26780180	HT29	viability (GeCKOv2 library)	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	1.08690952755612	[]	[]	5	hSpCas9	negative selection	4018814
17823193	17823216	1	-	26780180	HT29	viability (GeCKOv2 library)	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.905624363869304	[]	[]	4	hSpCas9	negative selection	4018815
17825921	17825944	1	-	26780180	HT29	viability (GeCKOv2 library)	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	1.3057088521733	[]	[]	6	hSpCas9	negative selection	4018816
17823007	17823030	1	-	26780180	HT29	viability (GeCKOv2 library)	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	1.01482305112711	[]	[]	4	hSpCas9	negative selection	4018817
17826051	17826074	1	+	26780180	HT29	viability (GeCKOv2 library)	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.316365482476463	[]	[]	0	hSpCas9	negative selection	4018818
17826235	17826258	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.12243324590049104	[3]	[2,2]	3	hSpCas9	positive selection	4187823
17823193	17823216	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	-0.08452813162634176	[2]	[1,1]	-2	hSpCas9	positive selection	4187834
17825921	17825944	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.011060815425330162	[4]	[3,2]	0	hSpCas9	positive selection	4187845
17823007	17823030	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.11681925506706708	[4]	[1,3]	3	hSpCas9	positive selection	4187856
17826051	17826074	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.6896968937378621	[4]	[6,3]	9	hSpCas9	positive selection	4187867
17823332	17823355	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCGGACCGAAAGAAGATGCTGG	ACTL8	ENSG00000117148	0.13754097461753528	[4]	[2,2]	3	hSpCas9	positive selection	4187878
17826235	17826258	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.5339201190935963	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4251845
17823193	17823216	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	-0.6817574185277487	[3]	[0,0,0,0]	-8	hSpCas9	positive selection	4251856
17825921	17825944	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.22521828819889084	[2]	[1,3,0,0]	1	hSpCas9	positive selection	4251867
17823007	17823030	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.6769275171016013	[1]	[0,3,1,0]	4	hSpCas9	positive selection	4251878
17826051	17826074	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	1.0933638190817383	[4]	[3,0,4,5]	8	hSpCas9	positive selection	4251889
17823332	17823355	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCGGACCGAAAGAAGATGCTGG	ACTL8	ENSG00000117148	0.01530094111801818	[3]	[2,1,1,0]	0	hSpCas9	positive selection	4251900
17825921	17825944	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	-0.32485576910440384	[1]	[1,0]	-6	hSpCas9	positive selection	4254335
17823007	17823030	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.1495732961417218	[2]	[2,1]	3	hSpCas9	positive selection	4254336
17826051	17826074	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.6262034407755255	[0]	[0,0]	9	hSpCas9	positive selection	4254337
17823139	17823162	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	-0.031669217350089984	[1]	[1,0]	0	hSpCas9	positive selection	4318618
17826235	17826258	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.23287712645891373	[2]	[1,0]	-5	hSpCas9	positive selection	4318619
17823193	17823216	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.28685726880905554	[1]	[2,0]	6	hSpCas9	positive selection	4318620
17823105	17823127	1	+	27760321	OCIAML3	viability	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	-0.47896158080134466	[706,589]	[285,461]	-5	hSpCas9	negative selection	4375896
17823137	17823159	1	-	27760321	OCIAML3	viability	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.708875029948772	[500,395]	[468,700]	8	hSpCas9	negative selection	4375897
17823196	17823218	1	+	27760321	OCIAML3	viability	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.39009454620073913	[782,570]	[635,753]	5	hSpCas9	negative selection	4375898
17823297	17823319	1	-	27760321	OCIAML3	viability	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-0.1715304545723209	[410,372]	[202,361]	-2	hSpCas9	negative selection	4375899
17825921	17825943	1	-	27760321	OCIAML3	viability	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.5417040161708733	[1213,996]	[1150,1384]	6	hSpCas9	negative selection	4375900
17823105	17823127	1	+	27760321	OCIAML2	viability	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.34939154800953043	[706,589]	[596,755]	5	hSpCas9	negative selection	4459359
17823137	17823159	1	-	27760321	OCIAML2	viability	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.7132611089652904	[500,395]	[578,606]	8	hSpCas9	negative selection	4459360
17823196	17823218	1	+	27760321	OCIAML2	viability	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	-0.0165272293421741	[782,570]	[499,583]	0	hSpCas9	negative selection	4459361
17823297	17823319	1	-	27760321	OCIAML2	viability	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-0.09494511878137984	[410,372]	[234,377]	-1	hSpCas9	negative selection	4459362
17825921	17825943	1	-	27760321	OCIAML2	viability	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.5380941954574694	[1213,996]	[1048,1612]	7	hSpCas9	negative selection	4459363
17823105	17823127	1	+	27760321	MV411	viability	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.8401811698971451	[706,589]	[742,792]	6	hSpCas9	negative selection	4542822
17823137	17823159	1	-	27760321	MV411	viability	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.2491434385705666	[500,395]	[265,474]	1	hSpCas9	negative selection	4542823
17823196	17823218	1	+	27760321	MV411	viability	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	-0.176572550455672	[782,570]	[36,923]	-1	hSpCas9	negative selection	4542824
17823297	17823319	1	-	27760321	MV411	viability	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	0.6184119448174019	[410,372]	[453,310]	4	hSpCas9	negative selection	4542825
17825921	17825943	1	-	27760321	MV411	viability	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	1.0297140033390766	[1213,996]	[1596,1309]	7	hSpCas9	negative selection	4542826
17823105	17823127	1	+	27760321	HL60	viability	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.5468655107195921	[706,589]	[777,762]	6	hSpCas9	negative selection	4626285
17823137	17823159	1	-	27760321	HL60	viability	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.29319562168603436	[500,395]	[415,477]	3	hSpCas9	negative selection	4626286
17823196	17823218	1	+	27760321	HL60	viability	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.17501900787951052	[782,570]	[514,727]	2	hSpCas9	negative selection	4626287
17823297	17823319	1	-	27760321	HL60	viability	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	0.3335008680383428	[410,372]	[343,465]	4	hSpCas9	negative selection	4626288
17825921	17825943	1	-	27760321	HL60	viability	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.37693975793736256	[1213,996]	[1186,1145]	4	hSpCas9	negative selection	4626289
17823105	17823127	1	+	27760321	HT1080	viability	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.6865789081868969	[589,460]	[198,487]	3	hSpCas9	negative selection	4709748
17823137	17823159	1	-	27760321	HT1080	viability	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	1.007742192316396	[395,308]	[173,400]	5	hSpCas9	negative selection	4709749
17823196	17823218	1	+	27760321	HT1080	viability	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	-1.0205140176219567	[570,445]	[117,79]	-4	hSpCas9	negative selection	4709750
17823297	17823319	1	-	27760321	HT1080	viability	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-1.3554746129486333	[372,290]	[23,81]	-5	hSpCas9	negative selection	4709751
17825921	17825943	1	-	27760321	HT1080	viability	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.8416785028989962	[996,777]	[793,457]	4	hSpCas9	negative selection	4709752
17823105	17823127	1	+	27760321	HT29	viability after 7 days	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.20056793552754604	[589,460]	[959,857,543]	3	hSpCas9	negative selection	4793211
17823137	17823159	1	-	27760321	HT29	viability after 7 days	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.6866557366124656	[395,308]	[674,820,684]	9	hSpCas9	negative selection	4793212
17823196	17823218	1	+	27760321	HT29	viability after 7 days	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.06973572282181284	[570,445]	[685,571,795]	1	hSpCas9	negative selection	4793213
17823297	17823319	1	-	27760321	HT29	viability after 7 days	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-0.021526128878437883	[372,290]	[460,488,319]	0	hSpCas9	negative selection	4793214
17825921	17825943	1	-	27760321	HT29	viability after 7 days	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.0724799264172673	[996,777]	[1260,1128,1215]	1	hSpCas9	negative selection	4793215
17823105	17823127	1	+	27760321	HT29	viability after 25 days	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.6054826775944064	[589,460]	[743,1167,829]	6	hSpCas9	negative selection	4876674
17823137	17823159	1	-	27760321	HT29	viability after 25 days	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.8156959549596201	[395,308]	[786,531,812]	8	hSpCas9	negative selection	4876675
17823196	17823218	1	+	27760321	HT29	viability after 25 days	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.152150312366789	[570,445]	[706,549,678]	1	hSpCas9	negative selection	4876676
17823297	17823319	1	-	27760321	HT29	viability after 25 days	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-0.033187933277703335	[372,290]	[468,313,316]	0	hSpCas9	negative selection	4876677
17825921	17825943	1	-	27760321	HT29	viability after 25 days	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.4227144291375451	[996,777]	[1579,1197,1275]	4	hSpCas9	negative selection	4876678
17823105	17823127	1	+	27760321	HT29	viability after 22 days	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.7023056954249063	[589,460]	[1063,967,930]	7	hSpCas9	negative selection	4960137
17823137	17823159	1	-	27760321	HT29	viability after 22 days	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.5900760525585601	[395,308]	[610,543,685]	6	hSpCas9	negative selection	4960138
17823196	17823218	1	+	27760321	HT29	viability after 22 days	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.34971498350776775	[570,445]	[1016,489,732]	4	hSpCas9	negative selection	4960139
17823297	17823319	1	-	27760321	HT29	viability after 22 days	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-0.2796081125223706	[372,290]	[192,322,436]	-3	hSpCas9	negative selection	4960140
17825921	17825943	1	-	27760321	HT29	viability after 22 days	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.4648186204128195	[996,777]	[1592,1147,1502]	5	hSpCas9	negative selection	4960141
17823105	17823127	1	+	27760321	HT29	viability after 19 days	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.555963306663162	[589,460]	[1162,752,767]	5	hSpCas9	negative selection	5043600
17823137	17823159	1	-	27760321	HT29	viability after 19 days	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.5350146581036442	[395,308]	[664,605,492]	5	hSpCas9	negative selection	5043601
17823196	17823218	1	+	27760321	HT29	viability after 19 days	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.0316565498677589	[570,445]	[745,647,411]	0	hSpCas9	negative selection	5043602
17823297	17823319	1	-	27760321	HT29	viability after 19 days	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	0.21650894575965446	[372,290]	[510,417,402]	2	hSpCas9	negative selection	5043603
17825921	17825943	1	-	27760321	HT29	viability after 19 days	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.528452547883282	[996,777]	[1514,1486,1396]	5	hSpCas9	negative selection	5043604
17823105	17823127	1	+	27760321	HT29	viability after 16 days	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.6732254069476533	[589,460]	[1156,913,762]	7	hSpCas9	negative selection	5127063
17823137	17823159	1	-	27760321	HT29	viability after 16 days	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.7750525103234811	[395,308]	[549,548,916]	8	hSpCas9	negative selection	5127064
17823196	17823218	1	+	27760321	HT29	viability after 16 days	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	-0.1856314671289403	[570,445]	[644,474,394]	-2	hSpCas9	negative selection	5127065
17823297	17823319	1	-	27760321	HT29	viability after 16 days	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-0.3535508085474637	[372,290]	[521,210,162]	-4	hSpCas9	negative selection	5127066
17825921	17825943	1	-	27760321	HT29	viability after 16 days	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.5107864409219756	[996,777]	[1193,1612,1410]	6	hSpCas9	negative selection	5127067
17823105	17823127	1	+	27760321	HT29	viability after 13 days	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.6987405561974156	[589,460]	[956,1335,693]	8	hSpCas9	negative selection	5210526
17823137	17823159	1	-	27760321	HT29	viability after 13 days	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.4653314076026683	[395,308]	[621,429,636]	6	hSpCas9	negative selection	5210527
17823196	17823218	1	+	27760321	HT29	viability after 13 days	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.3309708724869391	[570,445]	[854,921,465]	4	hSpCas9	negative selection	5210528
17823297	17823319	1	-	27760321	HT29	viability after 13 days	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-0.4568704481987493	[372,290]	[162,465,216]	-5	hSpCas9	negative selection	5210529
17825921	17825943	1	-	27760321	HT29	viability after 13 days	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.7112213629294608	[996,777]	[1965,1354,1731]	8	hSpCas9	negative selection	5210530
17823105	17823127	1	+	27760321	HT29	viability after 10 days	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	0.4538281607038426	[589,460]	[1098,1008,597]	6	hSpCas9	negative selection	5293989
17823137	17823159	1	-	27760321	HT29	viability after 10 days	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.40434389274384275	[395,308]	[759,415,566]	5	hSpCas9	negative selection	5293990
17823196	17823218	1	+	27760321	HT29	viability after 10 days	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	0.07633441495302351	[570,445]	[721,702,585]	1	hSpCas9	negative selection	5293991
17823297	17823319	1	-	27760321	HT29	viability after 10 days	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-0.056442199317790875	[372,290]	[323,476,396]	0	hSpCas9	negative selection	5293992
17825921	17825943	1	-	27760321	HT29	viability after 10 days	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.45676498474141236	[996,777]	[1400,1811,1360]	6	hSpCas9	negative selection	5293993
17823105	17823127	1	+	27760321	MOLM13	viability	GTGAACTACCTACCGTGCAAGG	ACTL8	ENSG00000117148	-0.510458610109788	[706,589]	[224,281]	-3	hSpCas9	negative selection	5377452
17823137	17823159	1	-	27760321	MOLM13	viability	ACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.62657679867473	[500,395]	[324,441]	4	hSpCas9	negative selection	5377453
17823196	17823218	1	+	27760321	MOLM13	viability	TTAGCTACCCCATCGAGCGGGG	ACTL8	ENSG00000117148	-0.3003108656298966	[782,570]	[263,343]	-2	hSpCas9	negative selection	5377454
17823297	17823319	1	-	27760321	MOLM13	viability	GTGTCTCCGTGATGATCACAGG	ACTL8	ENSG00000117148	-0.7083693070564913	[410,372]	[198,80]	-4	hSpCas9	negative selection	5377455
17825921	17825943	1	-	27760321	MOLM13	viability	AACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	1.4329325280022849	[1213,996]	[2859,667]	8	hSpCas9	negative selection	5377456
17825921	17825944	1	-	27260156	BXPC3	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.35051592391481234	[132]	[131,219,192,163]	7	hSpCas9	negative selection	5526795
17823007	17823030	1	-	27260156	BXPC3	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.3711964806411361	[343]	[382,408,463,634]	7	hSpCas9	negative selection	5526796
17826051	17826074	1	+	27260156	BXPC3	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.025369289119143268	[15]	[17,24,8,14]	0	hSpCas9	negative selection	5526797
17823139	17823162	1	-	27260156	BXPC3	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.1982218264384159	[144]	[177,139,209,167]	4	hSpCas9	negative selection	5591078
17826235	17826258	1	-	27260156	BXPC3	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.028262882073559425	[240]	[241,219,233,298]	0	hSpCas9	negative selection	5591079
17823193	17823216	1	-	27260156	BXPC3	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.2934561136250373	[131]	[173,208,156,126]	6	hSpCas9	negative selection	5591080
17825921	17825944	1	-	27260156	A673	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.14700504485227328	[132]	[177,175,177,174]	3	hSpCas9	negative selection	5648046
17823007	17823030	1	-	27260156	A673	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.045847184760466175	[343]	[480,385,405,439]	1	hSpCas9	negative selection	5648047
17826051	17826074	1	+	27260156	A673	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.41680376519320017	[15]	[25,4,0,27]	-8	hSpCas9	negative selection	5648048
17823139	17823162	1	-	27260156	A673	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.20959904955428188	[144]	[176,245,149,229]	5	hSpCas9	negative selection	5712329
17826235	17826258	1	-	27260156	A673	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.15035035558545817	[240]	[313,263,223,245]	-4	hSpCas9	negative selection	5712330
17823193	17823216	1	-	27260156	A673	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.12242495516571816	[131]	[238,144,133,180]	3	hSpCas9	negative selection	5712331
17825921	17825944	1	-	27260156	A375	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.5568634574637876	[132]	[278,169,260,198]	7	hSpCas9	negative selection	5769297
17823007	17823030	1	-	27260156	A375	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.339459654463235	[343]	[520,605,518,410]	5	hSpCas9	negative selection	5769298
17826051	17826074	1	+	27260156	A375	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.1363063274362446	[15]	[8,13,45,12]	2	hSpCas9	negative selection	5769299
17823139	17823162	1	-	27260156	A375	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.6931222479989774	[144]	[380,143,324,231]	8	hSpCas9	negative selection	5833580
17826235	17826258	1	-	27260156	A375	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.2786028565809888	[240]	[198,248,226,251]	-4	hSpCas9	negative selection	5833581
17823193	17823216	1	-	27260156	A375	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.08305045801346944	[131]	[144,158,194,153]	1	hSpCas9	negative selection	5833582
17825921	17825944	1	-	27260156	COLO741	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	1.0356387472376956	[132]	[410,296,341]	9	hSpCas9	negative selection	5890548
17823007	17823030	1	-	27260156	COLO741	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.1271099072048132	[343]	[567,575,314]	2	hSpCas9	negative selection	5890549
17826051	17826074	1	+	27260156	COLO741	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.5784638879496242	[15]	[32,0,8]	-8	hSpCas9	negative selection	5890550
17823139	17823162	1	-	27260156	COLO741	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.26471569968754305	[144]	[220,221,223]	5	hSpCas9	negative selection	5954831
17826235	17826258	1	-	27260156	COLO741	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.056344822466469546	[240]	[305,322,328]	1	hSpCas9	negative selection	5954832
17823193	17823216	1	-	27260156	COLO741	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.3030682697225391	[131]	[167,209,239]	6	hSpCas9	negative selection	5954833
17825921	17825944	1	-	27260156	CAL120	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.2930862622714441	[132]	[371,129,132]	4	hSpCas9	negative selection	6011799
17823007	17823030	1	-	27260156	CAL120	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	-0.061842853587692814	[343]	[447,385,401]	-1	hSpCas9	negative selection	6011800
17826051	17826074	1	+	27260156	CAL120	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-1.2862650843833778	[15]	[23,1,0]	-9	hSpCas9	negative selection	6011801
17823139	17823162	1	-	27260156	CAL120	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.08970866097137331	[144]	[294,190,106]	1	hSpCas9	negative selection	6076082
17826235	17826258	1	-	27260156	CAL120	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.42413897743476137	[240]	[691,346,214]	6	hSpCas9	negative selection	6076083
17823193	17823216	1	-	27260156	CAL120	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.3625008896417454	[131]	[131,359,130]	5	hSpCas9	negative selection	6076084
17825921	17825944	1	-	27260156	CADOES1	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.3576839086737129	[132]	[205,119,118,189]	6	hSpCas9	negative selection	6133050
17823007	17823030	1	-	27260156	CADOES1	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.4384873427036908	[343]	[440,497,423,368]	7	hSpCas9	negative selection	6133051
17826051	17826074	1	+	27260156	CADOES1	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.31008641172007945	[15]	[29,10,7,24]	5	hSpCas9	negative selection	6133052
17823139	17823162	1	-	27260156	CADOES1	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.6947156403636785	[144]	[208,338,142,180]	9	hSpCas9	negative selection	6197333
17826235	17826258	1	-	27260156	CADOES1	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.16776167517258844	[240]	[134,224,276,374]	3	hSpCas9	negative selection	6197334
17823193	17823216	1	-	27260156	CADOES1	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.1465350102829499	[131]	[177,175,118,67]	2	hSpCas9	negative selection	6197335
17825921	17825944	1	-	27260156	EWS502	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.08697046916681583	[132]	[112,202,165,115]	1	hSpCas9	negative selection	6254301
17823007	17823030	1	-	27260156	EWS502	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.47916523831209795	[343]	[499,514,414,605]	8	hSpCas9	negative selection	6254302
17826051	17826074	1	+	27260156	EWS502	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	1.0852080750104696	[15]	[37,39,15,49]	9	hSpCas9	negative selection	6254303
17823139	17823162	1	-	27260156	EWS502	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.29346400016500107	[144]	[148,219,194,191]	5	hSpCas9	negative selection	6318584
17826235	17826258	1	-	27260156	EWS502	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.11394714564761155	[240]	[299,228,203,198]	-2	hSpCas9	negative selection	6318585
17823193	17823216	1	-	27260156	EWS502	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.3674740964564558	[131]	[158,264,178,111]	6	hSpCas9	negative selection	6318586
17825921	17825944	1	-	27260156	EW8	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.38339490713036706	[132]	[149,187,106,123]	7	hSpCas9	negative selection	6375552
17823007	17823030	1	-	27260156	EW8	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.4391893009893616	[343]	[431,321,356,408]	7	hSpCas9	negative selection	6375553
17826051	17826074	1	+	27260156	EW8	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.7122139316222871	[15]	[0,6,0,22]	-8	hSpCas9	negative selection	6375554
17823139	17823162	1	-	27260156	EW8	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.7029801180759022	[144]	[198,209,212,139]	9	hSpCas9	negative selection	6439835
17826235	17826258	1	-	27260156	EW8	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.013356262991740975	[240]	[219,278,107,198]	0	hSpCas9	negative selection	6439836
17823193	17823216	1	-	27260156	EW8	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.1623855040391846	[131]	[136,106,103,134]	3	hSpCas9	negative selection	6439837
17825921	17825944	1	-	27260156	CORL105	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.3391936507859763	[132]	[149,266,234,138]	6	hSpCas9	negative selection	6496803
17823007	17823030	1	-	27260156	CORL105	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.06909512519947447	[343]	[527,385,413,364]	1	hSpCas9	negative selection	6496804
17826051	17826074	1	+	27260156	CORL105	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.7958654287128333	[15]	[38,18,72,5]	9	hSpCas9	negative selection	6496805
17823139	17823162	1	-	27260156	CORL105	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	-0.36740421407127677	[144]	[173,99,128,124]	-6	hSpCas9	negative selection	6561086
17826235	17826258	1	-	27260156	CORL105	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.003285451088062552	[240]	[327,230,309,263]	0	hSpCas9	negative selection	6561087
17823193	17823216	1	-	27260156	CORL105	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.4032597194796317	[131]	[150,172,317,191]	7	hSpCas9	negative selection	6561088
17825921	17825944	1	-	27260156	HS294T	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	-0.13030992445764755	[132]	[48,29,42,69]	-2	hSpCas9	negative selection	6618054
17823007	17823030	1	-	27260156	HS294T	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.7204788665037742	[343]	[149,217,113,436]	8	hSpCas9	negative selection	6618055
17826051	17826074	1	+	27260156	HS294T	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.045192086694741285	[15]	[17,0,1,2]	0	hSpCas9	negative selection	6618056
17823139	17823162	1	-	27260156	HS294T	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	1.0285745987166204	[144]	[92,117,48,215]	9	hSpCas9	negative selection	6682337
17826235	17826258	1	-	27260156	HS294T	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.22842631238631905	[240]	[103,42,83,86]	-3	hSpCas9	negative selection	6682338
17823193	17823216	1	-	27260156	HS294T	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.09753893575034622	[131]	[36,40,64,81]	1	hSpCas9	negative selection	6682339
17825921	17825944	1	-	27260156	HCC44	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.2574899118798293	[132]	[108,162,294,166]	4	hSpCas9	negative selection	6739305
17823007	17823030	1	-	27260156	HCC44	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.09805011107914585	[343]	[408,381,435,441]	1	hSpCas9	negative selection	6739306
17826051	17826074	1	+	27260156	HCC44	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.16609466503374737	[15]	[50,9,5,15]	2	hSpCas9	negative selection	6739307
17823139	17823162	1	-	27260156	HCC44	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.7675001437473827	[144]	[374,104,597,129]	9	hSpCas9	negative selection	6803588
17826235	17826258	1	-	27260156	HCC44	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.04047316045171867	[240]	[318,280,261,257]	0	hSpCas9	negative selection	6803589
17823193	17823216	1	-	27260156	HCC44	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.5481101997758548	[131]	[175,168,295,245]	8	hSpCas9	negative selection	6803590
17825921	17825944	1	-	27260156	G402	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.6656961002238015	[132]	[345,220,226,245]	7	hSpCas9	negative selection	6860556
17823007	17823030	1	-	27260156	G402	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.46369554486196224	[343]	[574,720,553,475]	6	hSpCas9	negative selection	6860557
17826051	17826074	1	+	27260156	G402	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.5398730130497142	[15]	[17,35,0,55]	6	hSpCas9	negative selection	6860558
17823139	17823162	1	-	27260156	G402	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.10668133657582568	[144]	[345,137,260,42]	1	hSpCas9	negative selection	6924839
17826235	17826258	1	-	27260156	G402	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.0777276803307454	[240]	[77,528,105,380]	-1	hSpCas9	negative selection	6924840
17823193	17823216	1	-	27260156	G402	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	1.3988726633002053	[131]	[116,290,535,687]	9	hSpCas9	negative selection	6924841
17825921	17825944	1	-	27260156	L33	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.18710069854891853	[132]	[145,43,120,159]	4	hSpCas9	negative selection	6981807
17823007	17823030	1	-	27260156	L33	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	-0.08479946488562218	[343]	[274,150,181,364]	-2	hSpCas9	negative selection	6981808
17826051	17826074	1	+	27260156	L33	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.6739050466692182	[15]	[6,3,10,5]	-9	hSpCas9	negative selection	6981809
17823139	17823162	1	-	27260156	L33	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.49434505525490935	[144]	[93,75,249,143]	8	hSpCas9	negative selection	7046090
17826235	17826258	1	-	27260156	L33	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.044681191636170015	[240]	[218,110,166,179]	-1	hSpCas9	negative selection	7046091
17823193	17823216	1	-	27260156	L33	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.2654561891325762	[131]	[91,92,117,129]	5	hSpCas9	negative selection	7046092
17825921	17825944	1	-	27260156	K562	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	-0.037774463659934865	[132]	[178,220,37,40]	0	hSpCas9	negative selection	7103058
17823007	17823030	1	-	27260156	K562	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.07871783362107165	[343]	[316,287,292,380]	1	hSpCas9	negative selection	7103059
17826051	17826074	1	+	27260156	K562	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-1.608970479227919	[15]	[0,0,0,13]	-9	hSpCas9	negative selection	7103060
17823139	17823162	1	-	27260156	K562	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.8255983578806171	[144]	[338,295,61,226]	9	hSpCas9	negative selection	7167341
17826235	17826258	1	-	27260156	K562	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.12376827055769712	[240]	[196,276,284,177]	1	hSpCas9	negative selection	7167342
17823193	17823216	1	-	27260156	K562	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.8299161477979853	[131]	[426,225,56,147]	9	hSpCas9	negative selection	7167343
17825921	17825944	1	-	27260156	HT29	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.38102349895095666	[132]	[178,430,160,99]	7	hSpCas9	negative selection	7224309
17823007	17823030	1	-	27260156	HT29	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.34651463509459735	[343]	[540,741,347,512]	6	hSpCas9	negative selection	7224310
17826051	17826074	1	+	27260156	HT29	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.02603590278067891	[15]	[45,5,8,18]	0	hSpCas9	negative selection	7224311
17823139	17823162	1	-	27260156	HT29	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.202220279019256	[144]	[290,239,142,151]	4	hSpCas9	negative selection	7288592
17826235	17826258	1	-	27260156	HT29	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.03513868751491489	[240]	[318,376,258,256]	0	hSpCas9	negative selection	7288593
17823193	17823216	1	-	27260156	HT29	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.1781241007188228	[131]	[224,167,196,141]	3	hSpCas9	negative selection	7288594
17825921	17825944	1	-	27260156	MHHES1	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.3765179840549153	[132]	[123,171,231,226]	6	hSpCas9	negative selection	7345560
17823007	17823030	1	-	27260156	MHHES1	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.23649077420914408	[343]	[355,610,423,432]	4	hSpCas9	negative selection	7345561
17826051	17826074	1	+	27260156	MHHES1	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	1.405165532957633	[15]	[15,168,11,9]	9	hSpCas9	negative selection	7345562
17823139	17823162	1	-	27260156	MHHES1	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.2571684946917536	[144]	[240,232,211,117]	5	hSpCas9	negative selection	7409843
17826235	17826258	1	-	27260156	MHHES1	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.03643827900184515	[240]	[307,259,324,227]	0	hSpCas9	negative selection	7409844
17823193	17823216	1	-	27260156	MHHES1	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.28955482217148565	[131]	[100,373,91,167]	5	hSpCas9	negative selection	7409845
17825921	17825944	1	-	27260156	MEWO	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.7445199708966712	[132]	[282,168,187]	9	hSpCas9	negative selection	7466811
17823007	17823030	1	-	27260156	MEWO	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.04729159633586566	[343]	[487,273,265]	1	hSpCas9	negative selection	7466812
17826051	17826074	1	+	27260156	MEWO	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.6455059266983829	[15]	[31,3,35]	9	hSpCas9	negative selection	7466813
17823139	17823162	1	-	27260156	MEWO	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	-0.23334777447596933	[144]	[113,93,137]	-5	hSpCas9	negative selection	7531094
17826235	17826258	1	-	27260156	MEWO	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.0008722100922261555	[240]	[306,178,205]	0	hSpCas9	negative selection	7531095
17823193	17823216	1	-	27260156	MEWO	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	-0.07157351701962966	[131]	[118,78,154]	-1	hSpCas9	negative selection	7531096
17825921	17825944	1	-	27260156	LNCAPCLONEFGC	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.7668493955240512	[132]	[203,289,209,110]	9	hSpCas9	negative selection	7588062
17823007	17823030	1	-	27260156	LNCAPCLONEFGC	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.4067026438661668	[343]	[359,503,499,295]	6	hSpCas9	negative selection	7588063
17826051	17826074	1	+	27260156	LNCAPCLONEFGC	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.35266811529533015	[15]	[59,1,2,6]	5	hSpCas9	negative selection	7588064
17823139	17823162	1	-	27260156	LNCAPCLONEFGC	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.4847243623590254	[144]	[205,118,217,200]	7	hSpCas9	negative selection	7652345
17826235	17826258	1	-	27260156	LNCAPCLONEFGC	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.22329098313652485	[240]	[352,159,243,264]	3	hSpCas9	negative selection	7652346
17823193	17823216	1	-	27260156	LNCAPCLONEFGC	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.0677320563029109	[131]	[107,83,136,176]	1	hSpCas9	negative selection	7652347
17825921	17825944	1	-	27260156	PANC0327	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	1.2589381757531781	[132]	[219,239,200,469]	9	hSpCas9	negative selection	7709313
17823007	17823030	1	-	27260156	PANC0327	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.3335466726780285	[343]	[451,434,279,371]	5	hSpCas9	negative selection	7709314
17826051	17826074	1	+	27260156	PANC0327	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-3.019460332105594	[15]	[1,1,1,0]	-9	hSpCas9	negative selection	7709315
17823139	17823162	1	-	27260156	PANC0327	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.7931168985526478	[144]	[120,312,331,106]	9	hSpCas9	negative selection	7773596
17826235	17826258	1	-	27260156	PANC0327	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.4659968027446567	[240]	[290,188,278,436]	7	hSpCas9	negative selection	7773597
17823193	17823216	1	-	27260156	PANC0327	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.11271315313325014	[131]	[233,39,85,166]	1	hSpCas9	negative selection	7773598
17825921	17825944	1	-	27260156	NCIH2009	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.6224317153777132	[132]	[499,230,169]	8	hSpCas9	negative selection	7830564
17823007	17823030	1	-	27260156	NCIH2009	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	-0.24072989490228158	[343]	[510,306,423]	-3	hSpCas9	negative selection	7830565
17826051	17826074	1	+	27260156	NCIH2009	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.10121619926489522	[15]	[6,6,45]	-1	hSpCas9	negative selection	7830566
17823139	17823162	1	-	27260156	NCIH2009	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.8892578863728839	[144]	[457,288,395]	9	hSpCas9	negative selection	7894847
17826235	17826258	1	-	27260156	NCIH2009	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.16389685532782905	[240]	[330,254,321]	-2	hSpCas9	negative selection	7894848
17823193	17823216	1	-	27260156	NCIH2009	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.6692757738159234	[131]	[392,241,264]	8	hSpCas9	negative selection	7894849
17825921	17825944	1	-	27260156	NCIH1373	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.4156101342799132	[132]	[113,350,78,58]	4	hSpCas9	negative selection	7951815
17823007	17823030	1	-	27260156	NCIH1373	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.39337717786080206	[343]	[621,372,556,131]	4	hSpCas9	negative selection	7951816
17826051	17826074	1	+	27260156	NCIH1373	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-2.400473828380501	[15]	[0,1,2,1]	-9	hSpCas9	negative selection	7951817
17823139	17823162	1	-	27260156	NCIH1373	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.39404826077799715	[144]	[325,68,234,67]	4	hSpCas9	negative selection	8016098
17826235	17826258	1	-	27260156	NCIH1373	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-1.0711336638137927	[240]	[214,96,110,27]	-8	hSpCas9	negative selection	8016099
17823193	17823216	1	-	27260156	NCIH1373	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.39405696019803016	[131]	[283,160,204,36]	4	hSpCas9	negative selection	8016100
17825921	17825944	1	-	27260156	PATU8902	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	1.7217579151066094	[132]	[509,409,304,1386]	9	hSpCas9	negative selection	8073066
17823007	17823030	1	-	27260156	PATU8902	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.7881071508485886	[343]	[800,770,664,1145]	8	hSpCas9	negative selection	8073067
17826051	17826074	1	+	27260156	PATU8902	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-4.159937960141519	[15]	[1,0,0,0]	-9	hSpCas9	negative selection	8073068
17823139	17823162	1	-	27260156	PATU8902	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.566045022016316	[144]	[119,473,284,323]	6	hSpCas9	negative selection	8137349
17826235	17826258	1	-	27260156	PATU8902	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.011697819430247947	[240]	[424,249,240,474]	0	hSpCas9	negative selection	8137350
17823193	17823216	1	-	27260156	PATU8902	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.07564269542173063	[131]	[273,150,141,221]	0	hSpCas9	negative selection	8137351
17825921	17825944	1	-	27260156	PANC1	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.7827352207127793	[132]	[173,375,150,129]	9	hSpCas9	negative selection	8194317
17823007	17823030	1	-	27260156	PANC1	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.19254067552756127	[343]	[419,476,273,219]	3	hSpCas9	negative selection	8194318
17826051	17826074	1	+	27260156	PANC1	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.36036962338305667	[15]	[3,32,0,32]	6	hSpCas9	negative selection	8194319
17823139	17823162	1	-	27260156	PANC1	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.3619044659109818	[144]	[100,295,126,144]	6	hSpCas9	negative selection	8258600
17826235	17826258	1	-	27260156	PANC1	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.13162470569149098	[240]	[223,256,160,132]	-2	hSpCas9	negative selection	8258601
17823193	17823216	1	-	27260156	PANC1	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	-0.038324919024343984	[131]	[110,156,149,42]	0	hSpCas9	negative selection	8258602
17825921	17825944	1	-	27260156	PANC0813	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.4961747579756375	[132]	[252,220,190,218]	7	hSpCas9	negative selection	8315568
17823007	17823030	1	-	27260156	PANC0813	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.22634254275469085	[343]	[724,392,343,451]	3	hSpCas9	negative selection	8315569
17826051	17826074	1	+	27260156	PANC0813	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.5643102085170932	[15]	[2,15,1,27]	-7	hSpCas9	negative selection	8315570
17823139	17823162	1	-	27260156	PANC0813	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.10860902274608719	[144]	[105,174,271,174]	1	hSpCas9	negative selection	8379851
17826235	17826258	1	-	27260156	PANC0813	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.014344815680580658	[240]	[215,329,206,356]	0	hSpCas9	negative selection	8379852
17823193	17823216	1	-	27260156	PANC0813	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.46682217054632447	[131]	[336,167,167,195]	7	hSpCas9	negative selection	8379853
17825921	17825944	1	-	27260156	RDES	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.7661764200521284	[132]	[220,237,249,346]	9	hSpCas9	negative selection	8436819
17823007	17823030	1	-	27260156	RDES	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.397948515458851	[343]	[373,509,543,703]	6	hSpCas9	negative selection	8436820
17826051	17826074	1	+	27260156	RDES	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.6806990940396487	[15]	[15,3,15,8]	-8	hSpCas9	negative selection	8436821
17823139	17823162	1	-	27260156	RDES	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.5944984460499922	[144]	[209,202,250,366]	8	hSpCas9	negative selection	8501102
17826235	17826258	1	-	27260156	RDES	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.163938042958361	[240]	[175,178,357,304]	-3	hSpCas9	negative selection	8501103
17823193	17823216	1	-	27260156	RDES	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	-0.08234614021903441	[131]	[101,188,149,130]	-1	hSpCas9	negative selection	8501104
17825921	17825944	1	-	27260156	PC3	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.2614989747170253	[132]	[112,129,343,123]	5	hSpCas9	negative selection	8558070
17823007	17823030	1	-	27260156	PC3	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	-0.15399812048521722	[343]	[162,416,376,333]	-3	hSpCas9	negative selection	8558071
17826051	17826074	1	+	27260156	PC3	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.19040053626721853	[15]	[9,2,50,6]	-4	hSpCas9	negative selection	8558072
17823139	17823162	1	-	27260156	PC3	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.3939869360173869	[144]	[180,137,243,197]	8	hSpCas9	negative selection	8622353
17826235	17826258	1	-	27260156	PC3	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.2306773379764946	[240]	[128,190,277,265]	-5	hSpCas9	negative selection	8622354
17823193	17823216	1	-	27260156	PC3	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.4168251556832343	[131]	[104,181,180,253]	8	hSpCas9	negative selection	8622355
17825921	17825944	1	-	27260156	PATU8988T	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.015195995655943095	[132]	[36,142,156,187]	0	hSpCas9	negative selection	8679321
17823007	17823030	1	-	27260156	PATU8988T	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	-0.11715159230187944	[343]	[211,308,385,318]	-2	hSpCas9	negative selection	8679322
17826051	17826074	1	+	27260156	PATU8988T	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-1.3491139534023562	[15]	[0,3,2,16]	-9	hSpCas9	negative selection	8679323
17823139	17823162	1	-	27260156	PATU8988T	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.23602421103982096	[144]	[135,232,189,101]	4	hSpCas9	negative selection	8743604
17826235	17826258	1	-	27260156	PATU8988T	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.14554344537589414	[240]	[183,202,183,275]	-2	hSpCas9	negative selection	8743605
17823193	17823216	1	-	27260156	PATU8988T	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.6114513775663655	[131]	[118,96,464,75]	8	hSpCas9	negative selection	8743606
17825921	17825944	1	-	27260156	T47D	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.38229034527385375	[132]	[268,148,147,248]	7	hSpCas9	negative selection	8800572
17823007	17823030	1	-	27260156	T47D	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.240808261540653	[343]	[518,444,559,367]	5	hSpCas9	negative selection	8800573
17826051	17826074	1	+	27260156	T47D	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-1.064394022920455	[15]	[6,16,2,7]	-9	hSpCas9	negative selection	8800574
17823139	17823162	1	-	27260156	T47D	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.09487213612617218	[144]	[131,133,152,310]	2	hSpCas9	negative selection	8864855
17826235	17826258	1	-	27260156	T47D	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.004964930152238645	[240]	[271,243,316,296]	0	hSpCas9	negative selection	8864856
17823193	17823216	1	-	27260156	T47D	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.35042770554064484	[131]	[171,136,238,241]	7	hSpCas9	negative selection	8864857
17825921	17825944	1	-	27260156	SU8686	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.37737841863699506	[132]	[146,121,182,254]	6	hSpCas9	negative selection	8921823
17823007	17823030	1	-	27260156	SU8686	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	-0.024065728433627864	[343]	[327,322,337,355]	0	hSpCas9	negative selection	8921824
17826051	17826074	1	+	27260156	SU8686	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.1519009342144768	[15]	[9,15,12,18]	-3	hSpCas9	negative selection	8921825
17823139	17823162	1	-	27260156	SU8686	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.5224031927763637	[144]	[165,135,250,301]	8	hSpCas9	negative selection	8986106
17826235	17826258	1	-	27260156	SU8686	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.20548767720181704	[240]	[201,234,362,323]	3	hSpCas9	negative selection	8986107
17823193	17823216	1	-	27260156	SU8686	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.18641846770373216	[131]	[164,113,137,185]	3	hSpCas9	negative selection	8986108
17825921	17825944	1	-	27260156	SKES1	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.504276564331466	[132]	[123,174,133,294]	8	hSpCas9	negative selection	9043074
17823007	17823030	1	-	27260156	SKES1	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.00701984301089581	[343]	[306,439,284,349]	0	hSpCas9	negative selection	9043075
17826051	17826074	1	+	27260156	SKES1	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.14437774562885597	[15]	[46,20,7,0]	3	hSpCas9	negative selection	9043076
17823139	17823162	1	-	27260156	SKES1	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.4514616132638585	[144]	[111,296,137,237]	8	hSpCas9	negative selection	9107357
17826235	17826258	1	-	27260156	SKES1	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.06321213572663975	[240]	[257,245,280,147]	-1	hSpCas9	negative selection	9107358
17823193	17823216	1	-	27260156	SKES1	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	-0.05450712435454452	[131]	[68,144,100,178]	-1	hSpCas9	negative selection	9107359
17825921	17825944	1	-	27260156	TOV112D	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.3202713345287751	[132]	[179,223,133,142]	6	hSpCas9	negative selection	9164325
17823007	17823030	1	-	27260156	TOV112D	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.012821811946699513	[343]	[462,451,297,215]	0	hSpCas9	negative selection	9164326
17826051	17826074	1	+	27260156	TOV112D	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	1.425164122688508	[15]	[6,9,31,109]	9	hSpCas9	negative selection	9164327
17823139	17823162	1	-	27260156	TOV112D	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	1.2238023500903545	[144]	[308,278,489,262]	9	hSpCas9	negative selection	9228608
17826235	17826258	1	-	27260156	TOV112D	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.28857554551811804	[240]	[125,334,89,264]	-5	hSpCas9	negative selection	9228609
17823193	17823216	1	-	27260156	TOV112D	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	-0.04012137574507135	[131]	[147,94,154,109]	-1	hSpCas9	negative selection	9228610
17825921	17825944	1	-	27260156	TC71	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.5920888202031744	[132]	[252,265,143,196]	9	hSpCas9	negative selection	9285576
17823007	17823030	1	-	27260156	TC71	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	-0.3824984245622317	[343]	[309,273,268,277]	-8	hSpCas9	negative selection	9285577
17826051	17826074	1	+	27260156	TC71	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	0.3389713169551367	[15]	[4,35,14,31]	7	hSpCas9	negative selection	9285578
17823139	17823162	1	-	27260156	TC71	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	-0.3033468316889796	[144]	[145,110,125,119]	-7	hSpCas9	negative selection	9349859
17826235	17826258	1	-	27260156	TC71	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	0.2795780386012985	[240]	[370,289,250,344]	6	hSpCas9	negative selection	9349860
17823193	17823216	1	-	27260156	TC71	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	0.23627322010831175	[131]	[188,188,148,137]	6	hSpCas9	negative selection	9349861
17825921	17825944	1	-	27260156	TC32	viability	GAACTCCAGCGTCTTGCCGCTGG	ACTL8	ENSG00000117148	0.6788246109810079	[132]	[199,179,176,235]	9	hSpCas9	negative selection	9406827
17823007	17823030	1	-	27260156	TC32	viability	GATAACGGTTCTTGCAGCCATGG	ACTL8	ENSG00000117148	0.3617951704033461	[343]	[402,202,644,515]	6	hSpCas9	negative selection	9406828
17826051	17826074	1	+	27260156	TC32	viability	GTGCTACGTGCCGCAGAATCTGG	ACTL8	ENSG00000117148	-0.28389918997269437	[15]	[4,6,38,4]	-5	hSpCas9	negative selection	9406829
17823139	17823162	1	-	27260156	TC32	viability	CACACGCCTACGGGCATAGCTGG	ACTL8	ENSG00000117148	0.3348905643395921	[144]	[222,59,162,271]	6	hSpCas9	negative selection	9471110
17826235	17826258	1	-	27260156	TC32	viability	ACGGATTCCACAATGGCCCGTGG	ACTL8	ENSG00000117148	-0.18425621169581574	[240]	[191,157,216,239]	-3	hSpCas9	negative selection	9471111
17823193	17823216	1	-	27260156	TC32	viability	CCGCTCGATGGGGTAGCTAAAGG	ACTL8	ENSG00000117148	-0.1493150456264798	[131]	[110,65,159,130]	-3	hSpCas9	negative selection	9471112
17823164	17823187	1	-	27869803	HPAFII	viability after 27 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	0.4909201433970647	[54]	[56,26,NaN]	4	hSpCas9	negative selection	9530862
17823216	17823239	1	+	27869803	HPAFII	viability after 27 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-1.2161282189009395	[232]	[79,29,NaN]	-7	hSpCas9	negative selection	9530863
17823330	17823353	1	-	27869803	HPAFII	viability after 27 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	1.1763104012572343	[42]	[37,61,NaN]	8	hSpCas9	negative selection	9530864
17825841	17825864	1	-	27869803	HPAFII	viability after 27 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.22644293934512416	[93]	[41,70,NaN]	1	hSpCas9	negative selection	9530865
17825884	17825907	1	+	27869803	HPAFII	viability after 27 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	-0.12806757517421086	[924]	[618,299,NaN]	-1	hSpCas9	negative selection	9530866
17826186	17826209	1	+	27869803	HPAFII	viability after 27 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	1.2191450475025944	[219]	[217,311,NaN]	8	hSpCas9	negative selection	9530867
17823164	17823187	1	-	27869803	HPAFII	viability after 15 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	0.05294680647298611	[54]	[93,40,NaN]	0	hSpCas9	negative selection	9613311
17823216	17823239	1	+	27869803	HPAFII	viability after 15 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.8568680512062209	[232]	[120,148,NaN]	-7	hSpCas9	negative selection	9613312
17823330	17823353	1	-	27869803	HPAFII	viability after 15 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	1.9071564702363084	[42]	[160,180,NaN]	9	hSpCas9	negative selection	9613313
17825841	17825864	1	-	27869803	HPAFII	viability after 15 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	1.0085922990091647	[93]	[267,162,NaN]	9	hSpCas9	negative selection	9613314
17825884	17825907	1	+	27869803	HPAFII	viability after 15 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.020082057633233674	[924]	[1287,833,NaN]	0	hSpCas9	negative selection	9613315
17826186	17826209	1	+	27869803	HPAFII	viability after 15 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.7728964130554956	[219]	[633,260,NaN]	8	hSpCas9	negative selection	9613316
17823164	17823187	1	-	27869803	ASPC1	viability after 36 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	-3.812295840823383	[88]	[0,0,3]	-9	hSpCas9	negative selection	9695760
17823216	17823239	1	+	27869803	ASPC1	viability after 36 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	0.30954349201318976	[350]	[23,50,319]	3	hSpCas9	negative selection	9695761
17823330	17823353	1	-	27869803	ASPC1	viability after 36 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	-2.0555714363608026	[187]	[0,11,28]	-9	hSpCas9	negative selection	9695762
17825841	17825864	1	-	27869803	ASPC1	viability after 36 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	1.4192316674733534	[401]	[716,103,346]	9	hSpCas9	negative selection	9695763
17825884	17825907	1	+	27869803	ASPC1	viability after 36 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	-0.22718601571158414	[2461]	[1123,834,372]	-2	hSpCas9	negative selection	9695764
17826186	17826209	1	+	27869803	ASPC1	viability after 36 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	-0.39936204378784057	[565]	[160,245,63]	-4	hSpCas9	negative selection	9695765
17823164	17823187	1	-	27869803	PATU8988S	viability after 35 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	0.25250993854700754	[74]	[28,42,NaN]	3	hSpCas9	negative selection	9778209
17823216	17823239	1	+	27869803	PATU8988S	viability after 35 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-1.1776252932281004	[423]	[71,78,NaN]	-8	hSpCas9	negative selection	9778210
17823330	17823353	1	-	27869803	PATU8988S	viability after 35 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	0.1816308250310028	[173]	[70,87,NaN]	2	hSpCas9	negative selection	9778211
17825841	17825864	1	-	27869803	PATU8988S	viability after 35 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-0.71126763652967	[552]	[150,120,NaN]	-6	hSpCas9	negative selection	9778212
17825884	17825907	1	+	27869803	PATU8988S	viability after 35 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.8218745997118417	[2183]	[1502,1606,NaN]	8	hSpCas9	negative selection	9778213
17826186	17826209	1	+	27869803	PATU8988S	viability after 35 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.35819993461134175	[458]	[219,253,NaN]	4	hSpCas9	negative selection	9778214
17823164	17823187	1	-	27869803	PATU8988S	viability after 31 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	0.3741316622285873	[74]	[36,40,NaN]	4	hSpCas9	negative selection	9860658
17823216	17823239	1	+	27869803	PATU8988S	viability after 31 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.5228079857334968	[423]	[85,157,NaN]	-5	hSpCas9	negative selection	9860659
17823330	17823353	1	-	27869803	PATU8988S	viability after 31 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	0.33889751653961664	[173]	[52,131,NaN]	4	hSpCas9	negative selection	9860660
17825841	17825864	1	-	27869803	PATU8988S	viability after 31 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-1.0070907180351287	[552]	[70,158,NaN]	-7	hSpCas9	negative selection	9860661
17825884	17825907	1	+	27869803	PATU8988S	viability after 31 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.6241349443990312	[2183]	[1138,1600,NaN]	7	hSpCas9	negative selection	9860662
17826186	17826209	1	+	27869803	PATU8988S	viability after 31 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	0.7018685225427275	[458]	[236,374,NaN]	7	hSpCas9	negative selection	9860663
17823164	17823187	1	-	27869803	HPAFII	viability after 35 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	-0.047343467517035	[54]	[33,18,NaN]	0	hSpCas9	negative selection	9943107
17823216	17823239	1	+	27869803	HPAFII	viability after 35 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	0.02384229878248069	[232]	[197,31,NaN]	0	hSpCas9	negative selection	9943108
17823330	17823353	1	-	27869803	HPAFII	viability after 35 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	1.0623019106079454	[42]	[20,72,NaN]	7	hSpCas9	negative selection	9943109
17825841	17825864	1	-	27869803	HPAFII	viability after 35 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	-0.011012351064481951	[93]	[26,69,NaN]	0	hSpCas9	negative selection	9943110
17825884	17825907	1	+	27869803	HPAFII	viability after 35 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.21333532572459202	[924]	[588,490,NaN]	1	hSpCas9	negative selection	9943111
17826186	17826209	1	+	27869803	HPAFII	viability after 35 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	1.7582720009855877	[219]	[269,496,NaN]	9	hSpCas9	negative selection	9943112
17823164	17823187	1	-	27869803	HPAFII	viability after 31 days	GATGGCAAATGTCGATGCCCAGG	ACTL8	ENSG00000117148	0.13157245994024658	[54]	[51,13,NaN]	0	hSpCas9	negative selection	10025556
17823216	17823239	1	+	27869803	HPAFII	viability after 31 days	GGCCGCATCCTCAACTGGGAGGG	ACTL8	ENSG00000117148	-0.2167589808745937	[232]	[179,38,NaN]	-1	hSpCas9	negative selection	10025557
17823330	17823353	1	-	27869803	HPAFII	viability after 31 days	AGCATCTTCTTTCGGTCCGCAGG	ACTL8	ENSG00000117148	1.4502509366736753	[42]	[19,115,NaN]	9	hSpCas9	negative selection	10025558
17825841	17825864	1	-	27869803	HPAFII	viability after 31 days	CAACCACCACTCCGGTCAGGAGG	ACTL8	ENSG00000117148	0.08060616408199572	[93]	[50,60,NaN]	0	hSpCas9	negative selection	10025559
17825884	17825907	1	+	27869803	HPAFII	viability after 31 days	CGCGTGCAGCCTTTCCACCAGGG	ACTL8	ENSG00000117148	0.06221068562545495	[924]	[608,468,NaN]	0	hSpCas9	negative selection	10025560
17826186	17826209	1	+	27869803	HPAFII	viability after 31 days	TGAGATGTTCTTTAGCCCGCAGG	ACTL8	ENSG00000117148	1.474316581332943	[219]	[187,511,NaN]	9	hSpCas9	negative selection	10025561
17823335	17823358	1	+	28162770	P31FUJ	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.37272161878909393	[208]	[317]	4	hSpCas9	negative selection	10106426
17823137	17823160	1	-	28162770	P31FUJ	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.41171714098723255	[86]	[135]	4	hSpCas9	negative selection	10106427
17823018	17823041	1	+	28162770	P31FUJ	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.7479187330907385	[112]	[222]	8	hSpCas9	negative selection	10106428
17823215	17823238	1	+	28162770	P31FUJ	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.00989919932240868	[392]	[464]	0	hSpCas9	negative selection	10106429
17823248	17823271	1	-	28162770	P31FUJ	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.44106971216897345	[214]	[342]	5	hSpCas9	negative selection	10106430
17823182	17823205	1	-	28162770	P31FUJ	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.6036990633027421	[55]	[99]	7	hSpCas9	negative selection	10106431
17823269	17823292	1	+	28162770	P31FUJ	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.5074385217846885	[263]	[440]	6	hSpCas9	negative selection	10106432
17823314	17823337	1	+	28162770	P31FUJ	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	-0.5115182324804421	[73]	[60]	-4	hSpCas9	negative selection	10106433
17823295	17823318	1	-	28162770	P31FUJ	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.07313385770508252	[380]	[470]	0	hSpCas9	negative selection	10106434
17823114	17823137	1	+	28162770	P31FUJ	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	-0.47158906400149514	[235]	[199]	-4	hSpCas9	negative selection	10106435
17823335	17823358	1	+	28162770	TF1	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	NaN	[NaN]	[260]	1	hSpCas9	negative selection	10275792
17823137	17823160	1	-	28162770	TF1	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10275793
17823018	17823041	1	+	28162770	TF1	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10275794
17823215	17823238	1	+	28162770	TF1	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	NaN	[NaN]	[366]	1	hSpCas9	negative selection	10275795
17823248	17823271	1	-	28162770	TF1	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	NaN	[NaN]	[285]	1	hSpCas9	negative selection	10275796
17823182	17823205	1	-	28162770	TF1	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10275797
17823269	17823292	1	+	28162770	TF1	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	NaN	[NaN]	[488]	1	hSpCas9	negative selection	10275798
17823314	17823337	1	+	28162770	TF1	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10275799
17823295	17823318	1	-	28162770	TF1	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10275800
17823114	17823137	1	+	28162770	TF1	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10275801
17823335	17823358	1	+	28162770	SKM1	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	-0.09821149260353265	[65]	[108]	-1	hSpCas9	negative selection	10445158
17823137	17823160	1	-	28162770	SKM1	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	-0.030588319833422917	[25]	[44]	0	hSpCas9	negative selection	10445159
17823018	17823041	1	+	28162770	SKM1	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.4285417636285914	[28]	[68]	4	hSpCas9	negative selection	10445160
17823215	17823238	1	+	28162770	SKM1	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	-0.6576148801211232	[115]	[129]	-5	hSpCas9	negative selection	10445161
17823248	17823271	1	-	28162770	SKM1	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.1428088735156945	[82]	[161]	1	hSpCas9	negative selection	10445162
17823182	17823205	1	-	28162770	SKM1	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	-1.4069641987431614	[23]	[15]	-7	hSpCas9	negative selection	10445163
17823269	17823292	1	+	28162770	SKM1	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.07490480901389068	[57]	[107]	0	hSpCas9	negative selection	10445164
17823314	17823337	1	+	28162770	SKM1	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	-0.27451390271951226	[12]	[18]	-2	hSpCas9	negative selection	10445165
17823295	17823318	1	-	28162770	SKM1	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-0.874469117916141	[83]	[80]	-6	hSpCas9	negative selection	10445166
17823114	17823137	1	+	28162770	SKM1	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	0.2823349617927301	[39]	[85]	2	hSpCas9	negative selection	10445167
17823335	17823358	1	+	28162770	SKM1	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	-0.09821149260353265	[65]	[108]	-1	hSpCas9	negative selection	10614524
17823137	17823160	1	-	28162770	SKM1	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	-0.030588319833422917	[25]	[44]	0	hSpCas9	negative selection	10614525
17823018	17823041	1	+	28162770	SKM1	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.4285417636285914	[28]	[68]	4	hSpCas9	negative selection	10614526
17823215	17823238	1	+	28162770	SKM1	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	-0.6576148801211232	[115]	[129]	-5	hSpCas9	negative selection	10614527
17823248	17823271	1	-	28162770	SKM1	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.1428088735156945	[82]	[161]	1	hSpCas9	negative selection	10614528
17823182	17823205	1	-	28162770	SKM1	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	-1.4069641987431614	[23]	[15]	-7	hSpCas9	negative selection	10614529
17823269	17823292	1	+	28162770	SKM1	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.07490480901389068	[57]	[107]	0	hSpCas9	negative selection	10614530
17823314	17823337	1	+	28162770	SKM1	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	-0.27451390271951226	[12]	[18]	-2	hSpCas9	negative selection	10614531
17823295	17823318	1	-	28162770	SKM1	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-0.874469117916141	[83]	[80]	-6	hSpCas9	negative selection	10614532
17823114	17823137	1	+	28162770	SKM1	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	0.2823349617927301	[39]	[85]	2	hSpCas9	negative selection	10614533
17823335	17823358	1	+	28162770	PL21	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.5857933069870698	[247]	[161]	5	hSpCas9	negative selection	10783890
17823137	17823160	1	-	28162770	PL21	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.6011019285564412	[102]	[67]	5	hSpCas9	negative selection	10783891
17823018	17823041	1	+	28162770	PL21	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.25185465103347554	[136]	[70]	2	hSpCas9	negative selection	10783892
17823215	17823238	1	+	28162770	PL21	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	-1.2009586938316499	[411]	[77]	-7	hSpCas9	negative selection	10783893
17823248	17823271	1	-	28162770	PL21	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	-0.41969334607888814	[334]	[108]	-3	hSpCas9	negative selection	10783894
17823182	17823205	1	-	28162770	PL21	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.6151771137681639	[59]	[39]	5	hSpCas9	negative selection	10783895
17823269	17823292	1	+	28162770	PL21	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.25747278955527175	[147]	[76]	2	hSpCas9	negative selection	10783896
17823314	17823337	1	+	28162770	PL21	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	1.8246304793971135	[23]	[36]	9	hSpCas9	negative selection	10783897
17823295	17823318	1	-	28162770	PL21	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.832834725994578	[217]	[168]	7	hSpCas9	negative selection	10783898
17823114	17823137	1	+	28162770	PL21	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	-1.1503576325948133	[203]	[39]	-6	hSpCas9	negative selection	10783899
17823335	17823358	1	+	28162770	P31FUJ	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.37272161878909393	[208]	[317]	4	hSpCas9	negative selection	10953256
17823137	17823160	1	-	28162770	P31FUJ	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	0.41171714098723255	[86]	[135]	4	hSpCas9	negative selection	10953257
17823018	17823041	1	+	28162770	P31FUJ	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.7479187330907385	[112]	[222]	8	hSpCas9	negative selection	10953258
17823215	17823238	1	+	28162770	P31FUJ	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.00989919932240868	[392]	[464]	0	hSpCas9	negative selection	10953259
17823248	17823271	1	-	28162770	P31FUJ	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.44106971216897345	[214]	[342]	5	hSpCas9	negative selection	10953260
17823182	17823205	1	-	28162770	P31FUJ	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.6036990633027421	[55]	[99]	7	hSpCas9	negative selection	10953261
17823269	17823292	1	+	28162770	P31FUJ	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.5074385217846885	[263]	[440]	6	hSpCas9	negative selection	10953262
17823314	17823337	1	+	28162770	P31FUJ	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	-0.5115182324804421	[73]	[60]	-4	hSpCas9	negative selection	10953263
17823295	17823318	1	-	28162770	P31FUJ	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.07313385770508252	[380]	[470]	0	hSpCas9	negative selection	10953264
17823114	17823137	1	+	28162770	P31FUJ	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	-0.47158906400149514	[235]	[199]	-4	hSpCas9	negative selection	10953265
17823335	17823358	1	+	28162770	OCIAML5	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	-0.08712540403660554	[142]	[242]	0	hSpCas9	negative selection	11122622
17823137	17823160	1	-	28162770	OCIAML5	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	1.6073650477733001	[35]	[197]	9	hSpCas9	negative selection	11122623
17823018	17823041	1	+	28162770	OCIAML5	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.7021336760864721	[78]	[231]	6	hSpCas9	negative selection	11122624
17823215	17823238	1	+	28162770	OCIAML5	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.5859727537764625	[209]	[568]	5	hSpCas9	negative selection	11122625
17823248	17823271	1	-	28162770	OCIAML5	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.23199769392447744	[174]	[370]	2	hSpCas9	negative selection	11122626
17823182	17823205	1	-	28162770	OCIAML5	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	-0.4735549476102672	[49]	[64]	-3	hSpCas9	negative selection	11122627
17823269	17823292	1	+	28162770	OCIAML5	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.40919874211674123	[135]	[325]	3	hSpCas9	negative selection	11122628
17823314	17823337	1	+	28162770	OCIAML5	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	1.022402547052144	[17]	[65]	8	hSpCas9	negative selection	11122629
17823295	17823318	1	-	28162770	OCIAML5	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-0.543944275501665	[209]	[259]	-4	hSpCas9	negative selection	11122630
17823114	17823137	1	+	28162770	OCIAML5	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	0.458456760751116	[126]	[314]	4	hSpCas9	negative selection	11122631
17823335	17823358	1	+	28162770	EOL1	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.21212436166711995	[407]	[248]	2	hSpCas9	negative selection	11291988
17823137	17823160	1	-	28162770	EOL1	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	-0.029648538816340775	[92]	[47]	0	hSpCas9	negative selection	11291989
17823018	17823041	1	+	28162770	EOL1	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.3845727256226885	[220]	[151]	3	hSpCas9	negative selection	11291990
17823215	17823238	1	+	28162770	EOL1	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	-0.1336152539876041	[657]	[315]	-1	hSpCas9	negative selection	11291991
17823248	17823271	1	-	28162770	EOL1	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.44974512743337725	[459]	[330]	4	hSpCas9	negative selection	11291992
17823182	17823205	1	-	28162770	EOL1	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.7266083939586255	[116]	[101]	6	hSpCas9	negative selection	11291993
17823269	17823292	1	+	28162770	EOL1	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	-1.9405226483433569	[305]	[41]	-8	hSpCas9	negative selection	11291994
17823314	17823337	1	+	28162770	EOL1	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	-0.6842614711049895	[60]	[19]	-5	hSpCas9	negative selection	11291995
17823295	17823318	1	-	28162770	EOL1	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-0.015509687973183417	[329]	[171]	0	hSpCas9	negative selection	11291996
17823114	17823137	1	+	28162770	EOL1	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	-0.08422243805719765	[164]	[81]	0	hSpCas9	negative selection	11291997
17823335	17823358	1	+	28162770	MOLM13	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	-0.05517858545063492	[364]	[253]	0	hSpCas9	negative selection	11461354
17823137	17823160	1	-	28162770	MOLM13	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	-0.20748841439879584	[106]	[66]	-1	hSpCas9	negative selection	11461355
17823018	17823041	1	+	28162770	MOLM13	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	1.1861184131291993	[185]	[305]	8	hSpCas9	negative selection	11461356
17823215	17823238	1	+	28162770	MOLM13	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.2837224575264877	[508]	[447]	2	hSpCas9	negative selection	11461357
17823248	17823271	1	-	28162770	MOLM13	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.7809644698779681	[424]	[527]	6	hSpCas9	negative selection	11461358
17823182	17823205	1	-	28162770	MOLM13	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	1.4390345188723934	[100]	[197]	9	hSpCas9	negative selection	11461359
17823269	17823292	1	+	28162770	MOLM13	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.3463274016636653	[296]	[272]	2	hSpCas9	negative selection	11461360
17823314	17823337	1	+	28162770	MOLM13	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	0.6764760033559962	[44]	[51]	5	hSpCas9	negative selection	11461361
17823295	17823318	1	-	28162770	MOLM13	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-1.216364039984367	[420]	[130]	-6	hSpCas9	negative selection	11461362
17823114	17823137	1	+	28162770	MOLM13	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	0.38277276790662795	[191]	[180]	3	hSpCas9	negative selection	11461363
17823335	17823358	1	+	28162770	HEL	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	1.3448848720918523	[259]	[422]	9	hSpCas9	negative selection	11630720
17823137	17823160	1	-	28162770	HEL	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	1.2634513576707151	[92]	[142]	9	hSpCas9	negative selection	11630721
17823018	17823041	1	+	28162770	HEL	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.13884794192651873	[172]	[121]	1	hSpCas9	negative selection	11630722
17823215	17823238	1	+	28162770	HEL	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.3542818292866564	[457]	[374]	3	hSpCas9	negative selection	11630723
17823248	17823271	1	-	28162770	HEL	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.2935892683779704	[320]	[251]	2	hSpCas9	negative selection	11630724
17823182	17823205	1	-	28162770	HEL	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.6427388320003571	[89]	[89]	5	hSpCas9	negative selection	11630725
17823269	17823292	1	+	28162770	HEL	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.4351434125919894	[290]	[251]	3	hSpCas9	negative selection	11630726
17823314	17823337	1	+	28162770	HEL	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	0.679264708025471	[38]	[39]	6	hSpCas9	negative selection	11630727
17823295	17823318	1	-	28162770	HEL	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.13046660868687254	[357]	[250]	1	hSpCas9	negative selection	11630728
17823114	17823137	1	+	28162770	HEL	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	0.6165865441443885	[166]	[163]	5	hSpCas9	negative selection	11630729
17823335	17823358	1	+	28162770	MV411	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	-0.04474320071053517	[239]	[195]	0	hSpCas9	negative selection	11800086
17823137	17823160	1	-	28162770	MV411	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	-0.4734083780201539	[88]	[53]	-3	hSpCas9	negative selection	11800087
17823018	17823041	1	+	28162770	MV411	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	-0.6539986147336351	[197]	[105]	-5	hSpCas9	negative selection	11800088
17823215	17823238	1	+	28162770	MV411	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.14607683582353426	[338]	[315]	1	hSpCas9	negative selection	11800089
17823248	17823271	1	-	28162770	MV411	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	-0.2809414215720135	[224]	[155]	-2	hSpCas9	negative selection	11800090
17823182	17823205	1	-	28162770	MV411	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.02787117352509072	[84]	[72]	0	hSpCas9	negative selection	11800091
17823269	17823292	1	+	28162770	MV411	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.6265905143630879	[172]	[224]	5	hSpCas9	negative selection	11800092
17823314	17823337	1	+	28162770	MV411	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	0.14310089096803935	[42]	[39]	1	hSpCas9	negative selection	11800093
17823295	17823318	1	-	28162770	MV411	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-0.31815962507144985	[295]	[199]	-2	hSpCas9	negative selection	11800094
17823114	17823137	1	+	28162770	MV411	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	-0.17918792277128048	[124]	[92]	-1	hSpCas9	negative selection	11800095
17823335	17823358	1	+	28162770	MONOMAC1	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.3272297219740484	[177]	[255]	3	hSpCas9	negative selection	11969452
17823137	17823160	1	-	28162770	MONOMAC1	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	-0.7689431949552634	[54]	[36]	-6	hSpCas9	negative selection	11969453
17823018	17823041	1	+	28162770	MONOMAC1	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.34776852718961987	[84]	[123]	3	hSpCas9	negative selection	11969454
17823215	17823238	1	+	28162770	MONOMAC1	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.09724849275867986	[273]	[335]	1	hSpCas9	negative selection	11969455
17823248	17823271	1	-	28162770	MONOMAC1	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.3464063842233355	[187]	[273]	3	hSpCas9	negative selection	11969456
17823182	17823205	1	-	28162770	MONOMAC1	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	0.4309943755534885	[54]	[84]	4	hSpCas9	negative selection	11969457
17823269	17823292	1	+	28162770	MONOMAC1	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.26862672528925824	[146]	[202]	2	hSpCas9	negative selection	11969458
17823314	17823337	1	+	28162770	MONOMAC1	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	1.519170186939855	[20]	[68]	9	hSpCas9	negative selection	11969459
17823295	17823318	1	-	28162770	MONOMAC1	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.2525738007667164	[133]	[182]	2	hSpCas9	negative selection	11969460
17823114	17823137	1	+	28162770	MONOMAC1	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	0.1341690614158194	[92]	[116]	1	hSpCas9	negative selection	11969461
17823335	17823358	1	+	28162770	OCIAML2	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	-0.15963129051305786	[52]	[262]	-1	hSpCas9	negative selection	12138818
17823137	17823160	1	-	28162770	OCIAML2	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	-0.622632918687211	[14]	[53]	-5	hSpCas9	negative selection	12138819
17823018	17823041	1	+	28162770	OCIAML2	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	0.7940734009522512	[17]	[172]	7	hSpCas9	negative selection	12138820
17823215	17823238	1	+	28162770	OCIAML2	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	0.29816525028440244	[64]	[442]	3	hSpCas9	negative selection	12138821
17823248	17823271	1	-	28162770	OCIAML2	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.1271567158365785	[55]	[338]	1	hSpCas9	negative selection	12138822
17823182	17823205	1	-	28162770	OCIAML2	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	-0.6038963561056256	[16]	[61]	-4	hSpCas9	negative selection	12138823
17823269	17823292	1	+	28162770	OCIAML2	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	0.40588712132283844	[31]	[234]	4	hSpCas9	negative selection	12138824
17823314	17823337	1	+	28162770	OCIAML2	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	-0.8267736354674367	[7]	[24]	-5	hSpCas9	negative selection	12138825
17823295	17823318	1	-	28162770	OCIAML2	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	0.14267730117295657	[41]	[256]	1	hSpCas9	negative selection	12138826
17823114	17823137	1	+	28162770	OCIAML2	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	-0.5084318579545456	[28]	[112]	-4	hSpCas9	negative selection	12138827
17823335	17823358	1	+	28162770	OCIAML3	viability	GGACCGAAAGAAGATGCTGGAGG	ACTL8	ENSG00000117148	0.5820695880997444	[51]	[234]	5	hSpCas9	negative selection	12308184
17823137	17823160	1	-	28162770	OCIAML3	viability	CACGCCTACGGGCATAGCTGGGG	ACTL8	ENSG00000117148	1.393919527375262	[14]	[118]	9	hSpCas9	negative selection	12308185
17823018	17823041	1	+	28162770	OCIAML3	viability	AGAACCGTTATCATTGACCACGG	ACTL8	ENSG00000117148	-0.4378884384068813	[34]	[77]	-3	hSpCas9	negative selection	12308186
17823215	17823238	1	+	28162770	OCIAML3	viability	GGGCCGCATCCTCAACTGGGAGG	ACTL8	ENSG00000117148	-0.2009964473753183	[98]	[259]	-1	hSpCas9	negative selection	12308187
17823248	17823271	1	-	28162770	OCIAML3	viability	TCTCCAACACAAATGACCAGAGG	ACTL8	ENSG00000117148	0.7530114355260296	[56]	[289]	6	hSpCas9	negative selection	12308188
17823182	17823205	1	-	28162770	OCIAML3	viability	GGTAGCTAAAGGTGTCAGGATGG	ACTL8	ENSG00000117148	1.38461870888327	[16]	[133]	9	hSpCas9	negative selection	12308189
17823269	17823292	1	+	28162770	OCIAML3	viability	GAACCACAGACGGGAGCAAGAGG	ACTL8	ENSG00000117148	-0.6603501351528592	[88]	[169]	-5	hSpCas9	negative selection	12308190
17823314	17823337	1	+	28162770	OCIAML3	viability	GACACCCTTGAGGGAGCCTGCGG	ACTL8	ENSG00000117148	1.3319917782320596	[4]	[37]	9	hSpCas9	negative selection	12308191
17823295	17823318	1	-	28162770	OCIAML3	viability	TGTCTCCGTGATGATCACAGGGG	ACTL8	ENSG00000117148	-0.22316994495585438	[57]	[149]	-2	hSpCas9	negative selection	12308192
17823114	17823137	1	+	28162770	OCIAML3	viability	CTACCGTGCAAGGAGAACCCTGG	ACTL8	ENSG00000117148	0.8178059580803944	[27]	[148]	7	hSpCas9	negative selection	12308193