Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10120
• Symbol:ACTR1B
• Description:actin related protein 1B

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTR1B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
97658982	97659005	2	-	26472758	Jiyoye	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.4007491123464406	[224]	[223]	3	hSpCas9	negative selection	2180
97659408	97659431	2	-	26472758	Jiyoye	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	0.20923600389396424	[38]	[33]	1	hSpCas9	negative selection	2181
97658442	97658465	2	+	26472758	Jiyoye	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	1.1149946300125628	[89]	[146]	7	hSpCas9	negative selection	2182
97659354	97659377	2	-	26472758	Jiyoye	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.0078621177729703	[159]	[59]	-6	hSpCas9	negative selection	2183
97658940	97658963	2	-	26472758	Jiyoye	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-0.03482916537323966	[71]	[52]	0	hSpCas9	negative selection	2184
97658596	97658619	2	-	26472758	Jiyoye	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	0.21013853444631972	[93]	[81]	1	hSpCas9	negative selection	2185
97658030	97658053	2	-	26472758	Jiyoye	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.9387416252489367	[210]	[304]	6	hSpCas9	negative selection	2186
97660621	97660644	2	-	26472758	Jiyoye	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	-1.1841848904134336	[225]	[74]	-7	hSpCas9	negative selection	2187
97660599	97660622	2	-	26472758	Jiyoye	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-0.7303281422440615	[43]	[19]	-5	hSpCas9	negative selection	2188
97659441	97659464	2	-	26472758	Jiyoye	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	-0.7854696964365224	[63]	[27]	-5	hSpCas9	negative selection	2189
97658982	97659005	2	-	26472758	KBM7	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.04048816963796209	[993,719]	[434,386]	0	hSpCas9	negative selection	193298
97659408	97659431	2	-	26472758	KBM7	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	0.3044022238609353	[191,206]	[81,147]	3	hSpCas9	negative selection	193299
97658442	97658465	2	+	26472758	KBM7	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.03332391479869547	[481,406]	[154,264]	0	hSpCas9	negative selection	193300
97659354	97659377	2	-	26472758	KBM7	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.2864498104479172	[1301,875]	[173,235]	-7	hSpCas9	negative selection	193301
97658940	97658963	2	-	26472758	KBM7	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	0.8052215028544841	[354,281]	[497,46]	8	hSpCas9	negative selection	193302
97658596	97658619	2	-	26472758	KBM7	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	-0.08131989304944565	[422,239]	[164,124]	-1	hSpCas9	negative selection	193303
97658030	97658053	2	-	26472758	KBM7	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.0797719596759432	[1227,1052]	[601,531]	0	hSpCas9	negative selection	193304
97660621	97660644	2	-	26472758	KBM7	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	0.32773343189700077	[489,451]	[265,288]	3	hSpCas9	negative selection	193305
97660599	97660622	2	-	26472758	KBM7	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-3.8215939644523464	[144,92]	[5,1]	-9	hSpCas9	negative selection	193306
97659441	97659464	2	-	26472758	KBM7	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.6090014586511718	[156,180]	[128,116]	6	hSpCas9	negative selection	193307
97658982	97659005	2	-	26472758	Raji	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	-0.33513470032735126	[423]	[77]	-3	hSpCas9	negative selection	384416
97659408	97659431	2	-	26472758	Raji	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	1.1275614173112296	[70]	[35]	8	hSpCas9	negative selection	384417
97658442	97658465	2	+	26472758	Raji	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.17540195880225062	[289]	[75]	1	hSpCas9	negative selection	384418
97659354	97659377	2	-	26472758	Raji	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-2.665205968523328	[491]	[17]	-9	hSpCas9	negative selection	384419
97658940	97658963	2	-	26472758	Raji	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	0.27730853681591183	[95]	[26]	2	hSpCas9	negative selection	384420
97658596	97658619	2	-	26472758	Raji	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	-2.005957937702345	[224]	[12]	-8	hSpCas9	negative selection	384421
97658030	97658053	2	-	26472758	Raji	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	-0.2915921904398462	[922]	[174]	-2	hSpCas9	negative selection	384422
97660621	97660644	2	-	26472758	Raji	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	0.032706849079103484	[336]	[79]	0	hSpCas9	negative selection	384423
97660599	97660622	2	-	26472758	Raji	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-1.384469560956075	[44]	[3]	-7	hSpCas9	negative selection	384424
97659441	97659464	2	-	26472758	Raji	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.16115479181458042	[157]	[40]	1	hSpCas9	negative selection	384425
97658982	97659005	2	-	26472758	K562	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	-0.4894821918669278	[626]	[376]	-3	hSpCas9	negative selection	575534
97659408	97659431	2	-	26472758	K562	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	-0.044086365683465356	[159]	[130]	0	hSpCas9	negative selection	575535
97658442	97658465	2	+	26472758	K562	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.01924386565867206	[345]	[295]	0	hSpCas9	negative selection	575536
97659354	97659377	2	-	26472758	K562	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-4.170618771612397	[831]	[38]	-9	hSpCas9	negative selection	575537
97658940	97658963	2	-	26472758	K562	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-1.3185174667247104	[194]	[65]	-6	hSpCas9	negative selection	575538
97658596	97658619	2	-	26472758	K562	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	-0.5645329793254867	[225]	[128]	-4	hSpCas9	negative selection	575539
97658030	97658053	2	-	26472758	K562	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.3151003653635027	[1174]	[1233]	2	hSpCas9	negative selection	575540
97660621	97660644	2	-	26472758	K562	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	-0.6629150241553209	[406]	[216]	-4	hSpCas9	negative selection	575541
97660599	97660622	2	-	26472758	K562	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-6.442081799516771	[102]	[0]	-9	hSpCas9	negative selection	575542
97659441	97659464	2	-	26472758	K562	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.6434082857134209	[112]	[148]	5	hSpCas9	negative selection	575543
97657157	97657180	2	-	26627737	DLD1	viability	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.9730079082201288	[395]	[78,37,69]	-7	hSpCas9	negative selection	813220
97657960	97657983	2	-	26627737	DLD1	viability	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-1.073157135670749	[410]	[117,73,0]	-7	hSpCas9	negative selection	813221
97658479	97658502	2	-	26627737	DLD1	viability	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.04602838642683017	[423]	[167,132,112]	0	hSpCas9	negative selection	813222
97658956	97658979	2	-	26627737	DLD1	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.03442642003829843	[1358]	[490,306,437]	0	hSpCas9	negative selection	813223
97659343	97659366	2	+	26627737	DLD1	viability	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	0.569436518361288	[1181]	[505,639,508]	6	hSpCas9	negative selection	813224
97660637	97660660	2	-	26627737	DLD1	viability	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.5378903693232221	[420]	[106,89,76]	-5	hSpCas9	negative selection	813225
97657157	97657180	2	-	26627737	GBM cells	viability after 5 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.5869698685709455	[107]	[88,84]	8	hSpCas9	negative selection	895535
97657960	97657983	2	-	26627737	GBM cells	viability after 5 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.3728907405758404	[98]	[47,33]	-5	hSpCas9	negative selection	895536
97658479	97658502	2	-	26627737	GBM cells	viability after 5 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	-0.49490713848346246	[179]	[69,66]	-7	hSpCas9	negative selection	895537
97658956	97658979	2	-	26627737	GBM cells	viability after 5 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.22375356519295098	[890]	[544,570]	3	hSpCas9	negative selection	895538
97659343	97659366	2	+	26627737	GBM cells	viability after 5 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.3264732440302396	[642]	[304,244]	-5	hSpCas9	negative selection	895539
97660637	97660660	2	-	26627737	GBM cells	viability after 5 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.18974374493471147	[150]	[69,71]	-3	hSpCas9	negative selection	895540
97657157	97657180	2	-	26627737	GBM cells	viability after 13 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.4203491253925733	[107]	[89,68]	5	hSpCas9	negative selection	977850
97657960	97657983	2	-	26627737	GBM cells	viability after 13 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.24787654978967488	[98]	[31,55]	-3	hSpCas9	negative selection	977851
97658479	97658502	2	-	26627737	GBM cells	viability after 13 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	-0.37824640898161666	[179]	[78,71]	-4	hSpCas9	negative selection	977852
97658956	97658979	2	-	26627737	GBM cells	viability after 13 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.5505019658143513	[890]	[787,642]	7	hSpCas9	negative selection	977853
97659343	97659366	2	+	26627737	GBM cells	viability after 13 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.2582011349863691	[642]	[401,201]	-3	hSpCas9	negative selection	977854
97660637	97660660	2	-	26627737	GBM cells	viability after 13 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.6096885035620864	[150]	[56,50]	-6	hSpCas9	negative selection	977855
97657157	97657180	2	-	26627737	GBM cells	viability after 21 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.8394386408982759	[107]	[116,93]	8	hSpCas9	negative selection	1060165
97657960	97657983	2	-	26627737	GBM cells	viability after 21 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.4069004633587414	[98]	[38,41]	-4	hSpCas9	negative selection	1060166
97658479	97658502	2	-	26627737	GBM cells	viability after 21 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.13731843911826597	[179]	[117,97]	1	hSpCas9	negative selection	1060167
97658956	97658979	2	-	26627737	GBM cells	viability after 21 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.6470057162648284	[890]	[757,757]	6	hSpCas9	negative selection	1060168
97659343	97659366	2	+	26627737	GBM cells	viability after 21 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.1741281910764958	[642]	[306,311]	-1	hSpCas9	negative selection	1060169
97660637	97660660	2	-	26627737	GBM cells	viability after 21 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.4419602161244237	[150]	[62,57]	-4	hSpCas9	negative selection	1060170
97657157	97657180	2	-	26627737	RPE1	viability after 9 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.1747922489510091	[439]	[151,159]	1	hSpCas9	negative selection	1142480
97657960	97657983	2	-	26627737	RPE1	viability after 9 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.5815109736784301	[328]	[15,136]	-4	hSpCas9	negative selection	1142481
97658479	97658502	2	-	26627737	RPE1	viability after 9 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	1.224835124047909	[297]	[152,301]	7	hSpCas9	negative selection	1142482
97658956	97658979	2	-	26627737	RPE1	viability after 9 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.5885601962156397	[2523]	[1337,994]	4	hSpCas9	negative selection	1142483
97659343	97659366	2	+	26627737	RPE1	viability after 9 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-1.1071157769865767	[2431]	[390,304]	-7	hSpCas9	negative selection	1142484
97660637	97660660	2	-	26627737	RPE1	viability after 9 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-1.558078947853244	[1273]	[141,126]	-8	hSpCas9	negative selection	1142485
97657157	97657180	2	-	26627737	RPE1	viability after 12 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.034636553575681406	[439]	[140,99]	0	hSpCas9	negative selection	1224795
97657960	97657983	2	-	26627737	RPE1	viability after 12 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	0.6361058017041151	[328]	[166,105]	4	hSpCas9	negative selection	1224796
97658479	97658502	2	-	26627737	RPE1	viability after 12 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	1.0502430878193643	[297]	[90,244]	6	hSpCas9	negative selection	1224797
97658956	97658979	2	-	26627737	RPE1	viability after 12 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.5828129725786064	[2523]	[1088,937]	4	hSpCas9	negative selection	1224798
97659343	97659366	2	+	26627737	RPE1	viability after 12 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-1.17204915620027	[2431]	[492,74]	-7	hSpCas9	negative selection	1224799
97660637	97660660	2	-	26627737	RPE1	viability after 12 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-1.0504693305770112	[1273]	[207,119]	-6	hSpCas9	negative selection	1224800
97657157	97657180	2	-	26627737	RPE1	viability after 15 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.10405175013830803	[439]	[182,50]	0	hSpCas9	negative selection	1307110
97657960	97657983	2	-	26627737	RPE1	viability after 15 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.034158878129906034	[328]	[68,111]	0	hSpCas9	negative selection	1307111
97658479	97658502	2	-	26627737	RPE1	viability after 15 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.858901129707909	[297]	[102,200]	5	hSpCas9	negative selection	1307112
97658956	97658979	2	-	26627737	RPE1	viability after 15 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.5990193211698671	[2523]	[1392,780]	4	hSpCas9	negative selection	1307113
97659343	97659366	2	+	26627737	RPE1	viability after 15 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.7838818598835143	[2431]	[451,348]	-5	hSpCas9	negative selection	1307114
97660637	97660660	2	-	26627737	RPE1	viability after 15 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-1.2808630393566864	[1273]	[242,56]	-7	hSpCas9	negative selection	1307115
97657157	97657180	2	-	26627737	RPE1	viability after 18 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.30075858338623984	[439]	[107,83]	-2	hSpCas9	negative selection	1389425
97657960	97657983	2	-	26627737	RPE1	viability after 18 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	1.0467085220374441	[328]	[180,185]	6	hSpCas9	negative selection	1389426
97658479	97658502	2	-	26627737	RPE1	viability after 18 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.9240840076501202	[297]	[169,133]	5	hSpCas9	negative selection	1389427
97658956	97658979	2	-	26627737	RPE1	viability after 18 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.4714089204532963	[2523]	[809,1087]	3	hSpCas9	negative selection	1389428
97659343	97659366	2	+	26627737	RPE1	viability after 18 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-1.3563641835921159	[2431]	[338,167]	-7	hSpCas9	negative selection	1389429
97660637	97660660	2	-	26627737	RPE1	viability after 18 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.862117832464109	[1273]	[207,168]	-5	hSpCas9	negative selection	1389430
97657157	97657180	2	-	26627737	HeLa	viability after 8 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.3054808622105525	[231]	[181,81,122]	3	hSpCas9	negative selection	1471740
97657960	97657983	2	-	26627737	HeLa	viability after 8 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-1.1759568436657084	[347]	[122,76,16]	-8	hSpCas9	negative selection	1471741
97658479	97658502	2	-	26627737	HeLa	viability after 8 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	1.6244284492183902	[63]	[60,147,45]	9	hSpCas9	negative selection	1471742
97658956	97658979	2	-	26627737	HeLa	viability after 8 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.11574767824602983	[1263]	[809,384,636]	1	hSpCas9	negative selection	1471743
97659343	97659366	2	+	26627737	HeLa	viability after 8 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.27670327722315613	[1484]	[640,391,586]	-3	hSpCas9	negative selection	1471744
97660637	97660660	2	-	26627737	HeLa	viability after 8 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.2845073256979199	[347]	[113,121,133]	-3	hSpCas9	negative selection	1471745
97657157	97657180	2	-	26627737	HeLa	viability after 12 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	1.0371994701926002	[231]	[267,152,175]	7	hSpCas9	negative selection	1554055
97657960	97657983	2	-	26627737	HeLa	viability after 12 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.8442786953201487	[347]	[101,22,121]	-6	hSpCas9	negative selection	1554056
97658479	97658502	2	-	26627737	HeLa	viability after 12 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	1.4650560694678605	[63]	[70,72,74]	8	hSpCas9	negative selection	1554057
97658956	97658979	2	-	26627737	HeLa	viability after 12 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.05904734980521509	[1263]	[587,504,544]	0	hSpCas9	negative selection	1554058
97659343	97659366	2	+	26627737	HeLa	viability after 12 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.6069761230715744	[1484]	[579,260,387]	-5	hSpCas9	negative selection	1554059
97660637	97660660	2	-	26627737	HeLa	viability after 12 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.016355399846669505	[347]	[288,36,115]	0	hSpCas9	negative selection	1554060
97657157	97657180	2	-	26627737	HeLa	viability after 15 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.5883642318348627	[231]	[142,128,154]	5	hSpCas9	negative selection	1636370
97657960	97657983	2	-	26627737	HeLa	viability after 15 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-2.322045563562537	[347]	[0,23,62]	-9	hSpCas9	negative selection	1636371
97658479	97658502	2	-	26627737	HeLa	viability after 15 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	1.9643894791172651	[63]	[70,149,82]	9	hSpCas9	negative selection	1636372
97658956	97658979	2	-	26627737	HeLa	viability after 15 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.06979531469821665	[1263]	[495,642,476]	0	hSpCas9	negative selection	1636373
97659343	97659366	2	+	26627737	HeLa	viability after 15 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.24325544532838328	[1484]	[544,388,604]	-2	hSpCas9	negative selection	1636374
97660637	97660660	2	-	26627737	HeLa	viability after 15 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.37755786545264336	[347]	[296,65,187]	3	hSpCas9	negative selection	1636375
97657157	97657180	2	-	26627737	HeLa	viability after 18 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.5329936058872198	[231]	[90,99,154]	4	hSpCas9	negative selection	1718685
97657960	97657983	2	-	26627737	HeLa	viability after 18 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-2.26983506036858	[347]	[0,21,62]	-9	hSpCas9	negative selection	1718686
97658479	97658502	2	-	26627737	HeLa	viability after 18 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	1.9511862416308055	[63]	[45,123,82]	9	hSpCas9	negative selection	1718687
97658956	97658979	2	-	26627737	HeLa	viability after 18 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.0654818516644371	[1263]	[333,526,476]	0	hSpCas9	negative selection	1718688
97659343	97659366	2	+	26627737	HeLa	viability after 18 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.25603131250970756	[1484]	[368,306,604]	-2	hSpCas9	negative selection	1718689
97660637	97660660	2	-	26627737	HeLa	viability after 18 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.3308829178433187	[347]	[189,51,187]	2	hSpCas9	negative selection	1718690
97657157	97657180	2	-	26627737	HCT116	viability after 6 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.1396274473182061	[423]	[84,46]	-1	hSpCas9	negative selection	1801000
97657960	97657983	2	-	26627737	HCT116	viability after 6 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-1.1432059503842278	[330]	[0,35]	-6	hSpCas9	negative selection	1801001
97658479	97658502	2	-	26627737	HCT116	viability after 6 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	-0.1828214512164696	[466]	[132,26]	-1	hSpCas9	negative selection	1801002
97658956	97658979	2	-	26627737	HCT116	viability after 6 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.8427639051524141	[1917]	[815,388]	4	hSpCas9	negative selection	1801003
97659343	97659366	2	+	26627737	HCT116	viability after 6 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	0.6313448125881422	[2003]	[458,503]	3	hSpCas9	negative selection	1801004
97660637	97660660	2	-	26627737	HCT116	viability after 6 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-2.1329756942450233	[255]	[23,0]	-8	hSpCas9	negative selection	1801005
97657157	97657180	2	-	26627737	HCT116	viability after 8 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.6777465574967596	[192]	[26,43,126]	-7	hSpCas9	negative selection	1883315
97657960	97657983	2	-	26627737	HCT116	viability after 8 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-2.527997573730101	[227]	[7,26,29]	-9	hSpCas9	negative selection	1883316
97658479	97658502	2	-	26627737	HCT116	viability after 8 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.7027979415094863	[130]	[149,80,121]	6	hSpCas9	negative selection	1883317
97658956	97658979	2	-	26627737	HCT116	viability after 8 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.048903816344403994	[1023]	[552,566,629]	0	hSpCas9	negative selection	1883318
97659343	97659366	2	+	26627737	HCT116	viability after 8 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	0.12693169315038788	[838]	[388,583,538]	1	hSpCas9	negative selection	1883319
97660637	97660660	2	-	26627737	HCT116	viability after 8 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.395026158523217	[322]	[124,73,205]	-5	hSpCas9	negative selection	1883320
97657157	97657180	2	-	26627737	HCT116	viability after 9 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.311079334829222	[423]	[54,207]	2	hSpCas9	negative selection	1965630
97657960	97657983	2	-	26627737	HCT116	viability after 9 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-2.6667223390121184	[330]	[28,1]	-9	hSpCas9	negative selection	1965631
97658479	97658502	2	-	26627737	HCT116	viability after 9 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.27740635139029324	[466]	[187,121]	2	hSpCas9	negative selection	1965632
97658956	97658979	2	-	26627737	HCT116	viability after 9 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.07670834689301076	[1917]	[617,380]	0	hSpCas9	negative selection	1965633
97659343	97659366	2	+	26627737	HCT116	viability after 9 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.14422308128729222	[2003]	[839,202]	-1	hSpCas9	negative selection	1965634
97660637	97660660	2	-	26627737	HCT116	viability after 9 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.19985889401640988	[255]	[168,6]	1	hSpCas9	negative selection	1965635
97657157	97657180	2	-	26627737	HCT116	viability after 12 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.5078835157453279	[192]	[49,104,284]	5	hSpCas9	negative selection	2047945
97657960	97657983	2	-	26627737	HCT116	viability after 12 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-1.231166046461763	[227]	[85,48,14]	-8	hSpCas9	negative selection	2047946
97658479	97658502	2	-	26627737	HCT116	viability after 12 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.5391664716989804	[130]	[186,38,64]	5	hSpCas9	negative selection	2047947
97658956	97658979	2	-	26627737	HCT116	viability after 12 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.16691709679841438	[1023]	[529,564,722]	1	hSpCas9	negative selection	2047948
97659343	97659366	2	+	26627737	HCT116	viability after 12 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.542398039458904	[838]	[216,435,265]	-5	hSpCas9	negative selection	2047949
97660637	97660660	2	-	26627737	HCT116	viability after 12 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.36326114987054375	[322]	[188,95,104]	-4	hSpCas9	negative selection	2047950
97657157	97657180	2	-	26627737	HCT116	viability after 15 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.0429276133211447	[192]	[75,71,188]	0	hSpCas9	negative selection	2130260
97657960	97657983	2	-	26627737	HCT116	viability after 15 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-2.0012812671658033	[227]	[44,53,0]	-9	hSpCas9	negative selection	2130261
97658479	97658502	2	-	26627737	HCT116	viability after 15 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.8363354905698763	[130]	[221,85,105]	7	hSpCas9	negative selection	2130262
97658956	97658979	2	-	26627737	HCT116	viability after 15 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.25356416197305265	[1023]	[844,678,597]	2	hSpCas9	negative selection	2130263
97659343	97659366	2	+	26627737	HCT116	viability after 15 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	0.08342293666901024	[838]	[479,633,414]	0	hSpCas9	negative selection	2130264
97660637	97660660	2	-	26627737	HCT116	viability after 15 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.22746411987069443	[322]	[261,156,69]	-2	hSpCas9	negative selection	2130265
97657157	97657180	2	-	26627737	HCT116	viability after 18 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.40522884739800835	[192]	[36,35,143]	-4	hSpCas9	negative selection	2212575
97657960	97657983	2	-	26627737	HCT116	viability after 18 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.7545492485875869	[227]	[98,42,54]	-6	hSpCas9	negative selection	2212576
97658479	97658502	2	-	26627737	HCT116	viability after 18 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.05449657515633022	[130]	[101,44,50]	0	hSpCas9	negative selection	2212577
97658956	97658979	2	-	26627737	HCT116	viability after 18 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.21197489841622574	[1023]	[355,715,641]	1	hSpCas9	negative selection	2212578
97659343	97659366	2	+	26627737	HCT116	viability after 18 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	0.04647613796563799	[838]	[246,580,417]	0	hSpCas9	negative selection	2212579
97660637	97660660	2	-	26627737	HCT116	viability after 18 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.33468677452469014	[322]	[128,159,77]	-3	hSpCas9	negative selection	2212580
97658955	97658978	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCAACCCGAGTAAGAACCGGG	ACTR1B	ENSG00000115073	0.2359314783489091	[2,2]	[3,1]	5	hSpCas9	positive selection	2968746
97658960	97658983	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCTTACTCGGGTTGAGCGGGG	ACTR1B	ENSG00000115073	0.07796450621018786	[4,4]	[3,5]	1	hSpCas9	positive selection	2968747
97659354	97659377	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	0.8005043578562163	[3,3]	[5,6]	9	hSpCas9	positive selection	2968748
97660637	97660660	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.4458922452154764	[3,3]	[2,0]	-6	hSpCas9	positive selection	2968749
97658955	97658978	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCAACCCGAGTAAGAACCGGG	ACTR1B	ENSG00000115073	-0.339977436152467	[2,2]	[2,0]	-5	hSpCas9	positive selection	3036604
97658960	97658983	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCTTACTCGGGTTGAGCGGGG	ACTR1B	ENSG00000115073	0.06666257056301883	[4,4]	[5,2]	1	hSpCas9	positive selection	3036605
97659354	97659377	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-0.6526803839603871	[3,3]	[3,0]	-8	hSpCas9	positive selection	3036606
97660637	97660660	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.29792437839240604	[3,3]	[2,0]	-4	hSpCas9	positive selection	3036607
97660585	97660608		+	24336571	A375	resistance to PLX after 7 days	CGATGAAGAGGTCCCCCTCCAGG	ACTR1B	ENSG00000115073	0.06686839755597052	[18,20]	[21,18]	2	hSpCas9	positive selection	3160028
97660570	97660593		-	24336571	A375	resistance to PLX after 7 days	CTTCATCGGACCAAAAGCAGAGG	ACTR1B	ENSG00000115073	-0.4284410420568615	[9,5]	[4,6]	-9	hSpCas9	positive selection	3160035
97661924	97661947		-	24336571	A375	resistance to PLX after 7 days	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.11418247708484719	[1,1]	[1,1]	-4	hSpCas9	positive selection	3160044
97660622	97660645		-	24336571	A375	resistance to PLX after 7 days	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.13219120417504776	[9,12]	[13,10]	4	hSpCas9	positive selection	3160052
97660585	97660608		+	24336571	A375	resistance to PLX after 14 days	CGATGAAGAGGTCCCCCTCCAGG	ACTR1B	ENSG00000115073	-0.10856683883206836	[22,14]	[6,8]	-1	hSpCas9	positive selection	3217821
97660570	97660593		-	24336571	A375	resistance to PLX after 14 days	CTTCATCGGACCAAAAGCAGAGG	ACTR1B	ENSG00000115073	0.7234746699903689	[7,4]	[3,5]	6	hSpCas9	positive selection	3217828
97661924	97661947		-	24336571	A375	resistance to PLX after 14 days	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	0.9824828929532969	[1,1]	[1,1]	7	hSpCas9	positive selection	3217837
97660622	97660645		-	24336571	A375	resistance to PLX after 14 days	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.09473010013212481	[11,11]	[5,4]	1	hSpCas9	positive selection	3217845
97660585	97660608		+	24336571	A375	viability after 7 days	CGATGAAGAGGTCCCCCTCCAGG	ACTR1B	ENSG00000115073	0.29964736164289535	[16]	[18,20]	4	hSpCas9	negative selection	3275614
97660570	97660593		-	24336571	A375	viability after 7 days	CTTCATCGGACCAAAAGCAGAGG	ACTR1B	ENSG00000115073	-0.7799217162957122	[14]	[9,5]	-8	hSpCas9	negative selection	3275621
97661924	97661947		-	24336571	A375	viability after 7 days	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	0.39899891113541264	[1]	[1,1]	6	hSpCas9	negative selection	3275630
97660622	97660645		-	24336571	A375	viability after 7 days	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.0827037386039357	[10]	[9,12]	1	hSpCas9	negative selection	3275638
97660585	97660608		+	24336571	A375	viability after 14 days	CGATGAAGAGGTCCCCCTCCAGG	ACTR1B	ENSG00000115073	0.27265477200611427	[16]	[22,14]	3	hSpCas9	negative selection	3333407
97660570	97660593		-	24336571	A375	viability after 14 days	CTTCATCGGACCAAAAGCAGAGG	ACTR1B	ENSG00000115073	-1.0449047474656683	[14]	[7,4]	-8	hSpCas9	negative selection	3333414
97661924	97661947		-	24336571	A375	viability after 14 days	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	0.2046632139204041	[1]	[1,1]	2	hSpCas9	negative selection	3333423
97660622	97660645		-	24336571	A375	viability after 14 days	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.1949066256196366	[10]	[11,11]	2	hSpCas9	negative selection	3333431
97660622	97660645	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	2.933042695560343	[24,14]	[0,0]	8	hSpCas9	positive selection	3335437
97658956	97658979	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.1479543213790547	[171,166]	[0,0]	-1	hSpCas9	positive selection	3335438
97659378	97659401	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	2.303434106656479	[29,31]	[0,0]	8	hSpCas9	positive selection	3335439
97659418	97659441	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	1.2349583984173806	[64,64]	[0,0]	5	hSpCas9	positive selection	3354687
97658905	97658928	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.7978945928085378	[87,87]	[0,0]	4	hSpCas9	positive selection	3354688
97661924	97661947	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	1.8650087886670745	[41,41]	[0,0]	7	hSpCas9	positive selection	3354689
97658955	97658978	2	-	26780180	HT29	viability (Avana library 4 designs)	GCTCAACCCGAGTAAGAACCGGG	ACTR1B	ENSG00000115073	1.97707161451312	[]	[]	7	hSpCas9	negative selection	3404694
97658959	97658982	2	+	26780180	HT29	viability (Avana library 4 designs)	GTTCTTACTCGGGTTGAGCGGGG	ACTR1B	ENSG00000115073	0.640505294845515	[]	[]	2	hSpCas9	negative selection	3404695
97659354	97659377	2	-	26780180	HT29	viability (Avana library 4 designs)	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	3.20228459511217	[]	[]	8	hSpCas9	negative selection	3404696
97660637	97660660	2	-	26780180	HT29	viability (Avana library 4 designs)	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	1.59965820528631	[]	[]	6	hSpCas9	negative selection	3404697
97660637	97660660	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	3.498122135205	[]	[]	5	hSpCas9	negative selection	3476357
97658959	97658982	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCTTACTCGGGTTGAGCGGGG	ACTR1B	ENSG00000115073	3.12586144445004	[]	[]	5	hSpCas9	negative selection	3476358
97659354	97659377	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-7.83510845008553	[]	[]	-7	hSpCas9	negative selection	3476359
97658955	97658978	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCAACCCGAGTAAGAACCGGG	ACTR1B	ENSG00000115073	1.47457860923108	[]	[]	2	hSpCas9	negative selection	3476360
97659426	97659449	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCACGCCGTGCTCCATGGGG	ACTR1B	ENSG00000115073	3.78639042956054	[]	[]	6	hSpCas9	negative selection	3476361
97659441	97659464	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	2.38629461754957	[]	[]	3	hSpCas9	negative selection	3476362
97660637	97660660	2	-	26780180	A375	viability (Avana lentiGuide)	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.220370399120507	[]	[]	0	hSpCas9	negative selection	3585016
97658959	97658982	2	+	26780180	A375	viability (Avana lentiGuide)	GTTCTTACTCGGGTTGAGCGGGG	ACTR1B	ENSG00000115073	-2.62133408462909	[]	[]	-4	hSpCas9	negative selection	3585017
97659354	97659377	2	-	26780180	A375	viability (Avana lentiGuide)	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	29.0889622801903	[]	[]	9	hSpCas9	negative selection	3585018
97658955	97658978	2	-	26780180	A375	viability (Avana lentiGuide)	GCTCAACCCGAGTAAGAACCGGG	ACTR1B	ENSG00000115073	-4.46199373302229	[]	[]	-7	hSpCas9	negative selection	3585019
97659426	97659449	2	+	26780180	A375	viability (Avana lentiGuide)	GCACCACGCCGTGCTCCATGGGG	ACTR1B	ENSG00000115073	1.40117920029118	[]	[]	1	hSpCas9	negative selection	3585020
97659441	97659464	2	-	26780180	A375	viability (Avana lentiGuide)	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	-0.980463779246359	[]	[]	-1	hSpCas9	negative selection	3585021
97660637	97660660	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.04809731847633725	[5]	[6,4]	1	hSpCas9	positive selection	3693675
97658959	97658982	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCTTACTCGGGTTGAGCGGGG	ACTR1B	ENSG00000115073	0.02725815913028773	[6]	[6,5]	0	hSpCas9	positive selection	3693676
97659354	97659377	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.0131784838970124	[5]	[2,1]	-8	hSpCas9	positive selection	3693677
97658955	97658978	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCAACCCGAGTAAGAACCGGG	ACTR1B	ENSG00000115073	0.11443875988206992	[3]	[3,4]	3	hSpCas9	positive selection	3693678
97659426	97659449	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCACGCCGTGCTCCATGGGG	ACTR1B	ENSG00000115073	0.38986842365294455	[3]	[5,4]	9	hSpCas9	positive selection	3693679
97659441	97659464	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.0381810360607594	[5]	[5,5]	0	hSpCas9	positive selection	3693680
97660637	97660660	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.19353313518839735	[5]	[5,5]	5	hSpCas9	positive selection	3802282
97658959	97658982	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCTTACTCGGGTTGAGCGGGG	ACTR1B	ENSG00000115073	0.11038728224007938	[6]	[6,5]	2	hSpCas9	positive selection	3802283
97659354	97659377	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-0.6278494977660036	[5]	[3,1]	-7	hSpCas9	positive selection	3802284
97658955	97658978	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCAACCCGAGTAAGAACCGGG	ACTR1B	ENSG00000115073	0.19867420728234886	[4]	[5,3]	5	hSpCas9	positive selection	3802285
97659426	97659449	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCACGCCGTGCTCCATGGGG	ACTR1B	ENSG00000115073	-0.08146973861086931	[4]	[2,5]	-1	hSpCas9	positive selection	3802286
97659441	97659464	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.20271165184161533	[7]	[6,6]	5	hSpCas9	positive selection	3802287
97659418	97659441	2	-	26780180	A375	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	1.20528304169428	[]	[]	6	hSpCas9	negative selection	3910889
97658956	97658979	2	-	26780180	A375	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	1.3709349994913	[]	[]	7	hSpCas9	negative selection	3910890
97659378	97659401	2	-	26780180	A375	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.556915174592908	[]	[]	1	hSpCas9	negative selection	3910891
97658905	97658928	2	+	26780180	A375	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	1.16173539868751	[]	[]	6	hSpCas9	negative selection	3910892
97661924	97661947	2	-	26780180	A375	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	1.20770928946205	[]	[]	6	hSpCas9	negative selection	3910893
97660622	97660645	2	-	26780180	A375	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.689130951273945	[]	[]	2	hSpCas9	negative selection	3910894
97659418	97659441	2	-	26780180	HT29	viability (GeCKOv2 library)	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	1.18045227085445	[]	[]	6	hSpCas9	negative selection	4018855
97658956	97658979	2	-	26780180	HT29	viability (GeCKOv2 library)	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	1.79432304796849	[]	[]	8	hSpCas9	negative selection	4018856
97659378	97659401	2	-	26780180	HT29	viability (GeCKOv2 library)	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.956811078567006	[]	[]	4	hSpCas9	negative selection	4018857
97658905	97658928	2	+	26780180	HT29	viability (GeCKOv2 library)	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.983755582616561	[]	[]	4	hSpCas9	negative selection	4018858
97661924	97661947	2	-	26780180	HT29	viability (GeCKOv2 library)	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	1.3411372725427	[]	[]	6	hSpCas9	negative selection	4018859
97660622	97660645	2	-	26780180	HT29	viability (GeCKOv2 library)	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.336202028101007	[]	[]	0	hSpCas9	negative selection	4018860
97660585	97660608	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGATGAAGAGGTCCCCCTCCAGG	ACTR1B	ENSG00000115073	0.16743045572071524	[4]	[3,2]	4	hSpCas9	positive selection	4188075
97660570	97660593	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCATCGGACCAAAAGCAGAGG	ACTR1B	ENSG00000115073	-0.2594875880488733	[2]	[0,2]	-6	hSpCas9	positive selection	4188086
97661924	97661947	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.17171111175148424	[0]	[0,0]	-4	hSpCas9	positive selection	4188097
97660622	97660645	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	-0.03891029532592025	[3]	[2,2]	-1	hSpCas9	positive selection	4188108
97660585	97660608	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGATGAAGAGGTCCCCCTCCAGG	ACTR1B	ENSG00000115073	0.119508400736372	[4]	[4,3,0,0]	0	hSpCas9	positive selection	4252097
97660570	97660593	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCATCGGACCAAAAGCAGAGG	ACTR1B	ENSG00000115073	0.22848323399285708	[2]	[2,0,1,0]	1	hSpCas9	positive selection	4252108
97661924	97661947	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	0.31243492669284223	[1]	[0,0,0,0]	2	hSpCas9	positive selection	4252119
97660622	97660645	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	-0.25266662378650273	[3]	[2,0,0,0]	-4	hSpCas9	positive selection	4252130
97660622	97660645	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.37635040095329964	[0]	[1,0]	7	hSpCas9	positive selection	4254356
97658956	97658979	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.3150430422681413	[3]	[2,1]	-6	hSpCas9	positive selection	4254357
97659378	97659401	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.3562094882527743	[1]	[2,0]	7	hSpCas9	positive selection	4254358
97659418	97659441	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.19842399687759454	[1]	[2,1]	4	hSpCas9	positive selection	4318639
97658905	97658928	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.28607150684786686	[1]	[2,1]	6	hSpCas9	positive selection	4318640
97661924	97661947	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.7168242690785404	[1]	[0,0]	-9	hSpCas9	positive selection	4318641
97658620	97658642	2	-	27760321	OCIAML3	viability	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.2987161920378958	[606,443]	[429,592]	3	hSpCas9	negative selection	4375931
97658956	97658978	2	-	27760321	OCIAML3	viability	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.5741195281566226	[331,267]	[98,231]	-5	hSpCas9	negative selection	4375932
97659378	97659400	2	-	27760321	OCIAML3	viability	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.3127720535894455	[412,304]	[299,404]	3	hSpCas9	negative selection	4375933
97660574	97660596	2	+	27760321	OCIAML3	viability	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	0.1252438461130183	[563,528]	[383,573]	1	hSpCas9	negative selection	4375934
97660637	97660659	2	-	27760321	OCIAML3	viability	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.1406786185974752	[731,614]	[422,544]	-1	hSpCas9	negative selection	4375935
97658620	97658642	2	-	27760321	OCIAML2	viability	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.35951524745841457	[606,443]	[522,562]	5	hSpCas9	negative selection	4459394
97658956	97658978	2	-	27760321	OCIAML2	viability	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.31041440215337246	[331,267]	[275,329]	4	hSpCas9	negative selection	4459395
97659378	97659400	2	-	27760321	OCIAML2	viability	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.40701070142011714	[412,304]	[337,438]	5	hSpCas9	negative selection	4459396
97660574	97660596	2	+	27760321	OCIAML2	viability	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	0.36588081148681745	[563,528]	[431,751]	5	hSpCas9	negative selection	4459397
97660637	97660659	2	-	27760321	OCIAML2	viability	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.0155168405707794	[731,614]	[438,692]	0	hSpCas9	negative selection	4459398
97658620	97658642	2	-	27760321	MV411	viability	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.5689914197883272	[606,443]	[485,544]	4	hSpCas9	negative selection	4542857
97658956	97658978	2	-	27760321	MV411	viability	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.9356530425312198	[331,267]	[22,222]	-6	hSpCas9	negative selection	4542858
97659378	97659400	2	-	27760321	MV411	viability	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.199847437608985	[412,304]	[191,222]	-1	hSpCas9	negative selection	4542859
97660574	97660596	2	+	27760321	MV411	viability	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	-0.6643129351131623	[563,528]	[114,396]	-4	hSpCas9	negative selection	4542860
97660637	97660659	2	-	27760321	MV411	viability	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-1.4125209530395602	[731,614]	[63,319]	-7	hSpCas9	negative selection	4542861
97658620	97658642	2	-	27760321	HL60	viability	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.4793955233444317	[606,443]	[536,651]	6	hSpCas9	negative selection	4626320
97658956	97658978	2	-	27760321	HL60	viability	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	1.3323121997561977	[331,267]	[255,992]	9	hSpCas9	negative selection	4626321
97659378	97659400	2	-	27760321	HL60	viability	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.17485463882089797	[412,304]	[221,294]	-2	hSpCas9	negative selection	4626322
97660574	97660596	2	+	27760321	HL60	viability	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	1.4077267437873908	[563,528]	[943,1440]	9	hSpCas9	negative selection	4626323
97660637	97660659	2	-	27760321	HL60	viability	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.37493744267264695	[731,614]	[376,470]	-4	hSpCas9	negative selection	4626324
97658620	97658642	2	-	27760321	HT1080	viability	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.9426712800593904	[443,346]	[183,432]	5	hSpCas9	negative selection	4709783
97658956	97658978	2	-	27760321	HT1080	viability	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-1.0355096350444013	[267,208]	[0,95]	-4	hSpCas9	negative selection	4709784
97659378	97659400	2	-	27760321	HT1080	viability	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-1.3078631220739165	[304,237]	[15,73]	-5	hSpCas9	negative selection	4709785
97660574	97660596	2	+	27760321	HT1080	viability	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	0.5229335491919616	[528,412]	[292,243]	2	hSpCas9	negative selection	4709786
97660637	97660659	2	-	27760321	HT1080	viability	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.034073260981624554	[614,479]	[244,177]	0	hSpCas9	negative selection	4709787
97658620	97658642	2	-	27760321	HT29	viability after 7 days	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.1166042048204474	[443,346]	[597,449,609]	1	hSpCas9	negative selection	4793246
97658956	97658978	2	-	27760321	HT29	viability after 7 days	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.055263969408043456	[267,208]	[356,449,158]	0	hSpCas9	negative selection	4793247
97659378	97659400	2	-	27760321	HT29	viability after 7 days	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.30750560140155514	[304,237]	[789,365,197]	5	hSpCas9	negative selection	4793248
97660574	97660596	2	+	27760321	HT29	viability after 7 days	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	-0.18800186920698636	[528,412]	[565,662,374]	-3	hSpCas9	negative selection	4793249
97660637	97660659	2	-	27760321	HT29	viability after 7 days	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.1726035931862384	[614,479]	[1062,556,324]	-3	hSpCas9	negative selection	4793250
97658620	97658642	2	-	27760321	HT29	viability after 25 days	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.20436739282781288	[443,346]	[609,347,606]	2	hSpCas9	negative selection	4876709
97658956	97658978	2	-	27760321	HT29	viability after 25 days	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.2708310298355177	[267,208]	[212,341,450]	3	hSpCas9	negative selection	4876710
97659378	97659400	2	-	27760321	HT29	viability after 25 days	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.4994095947583537	[304,237]	[719,383,164]	5	hSpCas9	negative selection	4876711
97660574	97660596	2	+	27760321	HT29	viability after 25 days	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	-0.3360440700902083	[528,412]	[408,467,399]	-3	hSpCas9	negative selection	4876712
97660637	97660659	2	-	27760321	HT29	viability after 25 days	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.08558910528508734	[614,479]	[723,607,653]	0	hSpCas9	negative selection	4876713
97658620	97658642	2	-	27760321	HT29	viability after 22 days	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.341837901700344	[443,346]	[633,527,574]	3	hSpCas9	negative selection	4960172
97658956	97658978	2	-	27760321	HT29	viability after 22 days	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.3042553155377904	[267,208]	[166,213,290]	-3	hSpCas9	negative selection	4960173
97659378	97659400	2	-	27760321	HT29	viability after 22 days	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.26633146918346995	[304,237]	[244,519,370]	2	hSpCas9	negative selection	4960174
97660574	97660596	2	+	27760321	HT29	viability after 22 days	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	0.046841733499998095	[528,412]	[357,661,673]	0	hSpCas9	negative selection	4960175
97660637	97660659	2	-	27760321	HT29	viability after 22 days	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.38465829667550633	[614,479]	[1027,672,771]	4	hSpCas9	negative selection	4960176
97658620	97658642	2	-	27760321	HT29	viability after 19 days	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.7218173384829208	[443,346]	[600,486,1119]	7	hSpCas9	negative selection	5043635
97658956	97658978	2	-	27760321	HT29	viability after 19 days	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.467503935250577	[267,208]	[372,494,266]	4	hSpCas9	negative selection	5043636
97659378	97659400	2	-	27760321	HT29	viability after 19 days	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.37641894606668785	[304,237]	[403,668,145]	3	hSpCas9	negative selection	5043637
97660574	97660596	2	+	27760321	HT29	viability after 19 days	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	0.20947978114829785	[528,412]	[504,678,669]	2	hSpCas9	negative selection	5043638
97660637	97660659	2	-	27760321	HT29	viability after 19 days	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.0813708055273118	[614,479]	[707,641,442]	0	hSpCas9	negative selection	5043639
97658620	97658642	2	-	27760321	HT29	viability after 16 days	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.24519900798545044	[443,346]	[369,364,827]	2	hSpCas9	negative selection	5127098
97658956	97658978	2	-	27760321	HT29	viability after 16 days	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.04386122917397006	[267,208]	[464,102,231]	0	hSpCas9	negative selection	5127099
97659378	97659400	2	-	27760321	HT29	viability after 16 days	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.5594537187431907	[304,237]	[729,467,170]	6	hSpCas9	negative selection	5127100
97660574	97660596	2	+	27760321	HT29	viability after 16 days	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	-0.2624424296817096	[528,412]	[453,334,532]	-3	hSpCas9	negative selection	5127101
97660637	97660659	2	-	27760321	HT29	viability after 16 days	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.3294034544971951	[614,479]	[751,776,777]	3	hSpCas9	negative selection	5127102
97658620	97658642	2	-	27760321	HT29	viability after 13 days	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.5906242149426045	[443,346]	[688,626,752]	7	hSpCas9	negative selection	5210561
97658956	97658978	2	-	27760321	HT29	viability after 13 days	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.05279853366305043	[267,208]	[404,140,312]	0	hSpCas9	negative selection	5210562
97659378	97659400	2	-	27760321	HT29	viability after 13 days	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.20628546327112712	[304,237]	[378,312,395]	2	hSpCas9	negative selection	5210563
97660574	97660596	2	+	27760321	HT29	viability after 13 days	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	-0.12300739032908214	[528,412]	[695,532,288]	-1	hSpCas9	negative selection	5210564
97660637	97660659	2	-	27760321	HT29	viability after 13 days	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.16097791433698144	[614,479]	[545,551,603]	-2	hSpCas9	negative selection	5210565
97658620	97658642	2	-	27760321	HT29	viability after 10 days	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.5968143716532663	[443,346]	[611,816,811]	7	hSpCas9	negative selection	5294024
97658956	97658978	2	-	27760321	HT29	viability after 10 days	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.37364906414448024	[267,208]	[311,652,203]	5	hSpCas9	negative selection	5294025
97659378	97659400	2	-	27760321	HT29	viability after 10 days	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.20833863362625174	[304,237]	[392,473,311]	2	hSpCas9	negative selection	5294026
97660574	97660596	2	+	27760321	HT29	viability after 10 days	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	-0.3731379132424554	[528,412]	[666,456,242]	-5	hSpCas9	negative selection	5294027
97660637	97660659	2	-	27760321	HT29	viability after 10 days	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.09525332764787042	[614,479]	[905,418,853]	1	hSpCas9	negative selection	5294028
97658620	97658642	2	-	27760321	MOLM13	viability	ACGCAACAGGACGCACGACAGG	ACTR1B	ENSG00000115073	0.7564347142861272	[606,443]	[823,216]	5	hSpCas9	negative selection	5377487
97658956	97658978	2	-	27760321	MOLM13	viability	GCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.20288440981361344	[331,267]	[115,171]	-1	hSpCas9	negative selection	5377488
97659378	97659400	2	-	27760321	MOLM13	viability	TGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.0009331757417814779	[412,304]	[333,86]	0	hSpCas9	negative selection	5377489
97660574	97660596	2	+	27760321	MOLM13	viability	TGCTTTTGGTCCGATGAAGAGG	ACTR1B	ENSG00000115073	0.8505650216001917	[563,528]	[786,359]	6	hSpCas9	negative selection	5377490
97660637	97660659	2	-	27760321	MOLM13	viability	CCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.15230805468215536	[731,614]	[451,393]	1	hSpCas9	negative selection	5377491
97663725	97663748	2	+	27661255	K562	viability	GGCGACGGCCACGCAGTGAGCGG	ACTR1B	ENSG00000115073	-0.18476838826083958	[761,861]	[570,567]	-5	dCas9-KRAB	negative selection	5460763
97663923	97663946	2	+	27661255	K562	viability	GGCTGCAGGAGGCACCGGATGGG	ACTR1B	ENSG00000115073	0.0770009182134972	[1499,1596]	[1346,1265]	2	dCas9-KRAB	negative selection	5460764
97663966	97663989	2	+	27661255	K562	viability	GACGGCGGCGGCTCCCGACGCGG	ACTR1B	ENSG00000115073	0.1282221928360665	[594,804]	[616,599]	4	dCas9-KRAB	negative selection	5460765
97663979	97664002	2	-	27661255	K562	viability	GAGGGCAGCGGCGCCGCGTCGGG	ACTR1B	ENSG00000115073	-0.00799788745716332	[699,831]	[611,601]	0	dCas9-KRAB	negative selection	5460766
97660622	97660645	2	-	27260156	BXPC3	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.25931830693963587	[55]	[42,75,100,61]	5	hSpCas9	negative selection	5526816
97658956	97658979	2	-	27260156	BXPC3	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.40221838556724954	[639]	[503,500,522,492]	-7	hSpCas9	negative selection	5526817
97659378	97659401	2	-	27260156	BXPC3	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.13942439687914732	[88]	[95,104,41,91]	-3	hSpCas9	negative selection	5526818
97659418	97659441	2	-	27260156	BXPC3	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.09842440253175844	[189]	[279,106,197,269]	2	hSpCas9	negative selection	5591099
97658905	97658928	2	+	27260156	BXPC3	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.29328193149433	[142]	[167,143,221,204]	6	hSpCas9	negative selection	5591100
97661924	97661947	2	-	27260156	BXPC3	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.412817876657098	[154]	[142,62,101,186]	-7	hSpCas9	negative selection	5591101
97660622	97660645	2	-	27260156	A673	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.8918923402068302	[55]	[107,140,129,116]	9	hSpCas9	negative selection	5648067
97658956	97658979	2	-	27260156	A673	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.47873193038313794	[639]	[671,552,509,479]	-8	hSpCas9	negative selection	5648068
97659378	97659401	2	-	27260156	A673	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.09202120223496824	[88]	[145,105,85,121]	2	hSpCas9	negative selection	5648069
97659418	97659441	2	-	27260156	A673	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.08601147608619386	[189]	[382,195,183,221]	2	hSpCas9	negative selection	5712350
97658905	97658928	2	+	27260156	A673	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.027933957231428996	[142]	[152,194,185,161]	0	hSpCas9	negative selection	5712351
97661924	97661947	2	-	27260156	A673	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.8519697056235565	[154]	[108,84,90,129]	-9	hSpCas9	negative selection	5712352
97660622	97660645	2	-	27260156	A375	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.5231650736791553	[55]	[113,118,49,95]	7	hSpCas9	negative selection	5769318
97658956	97658979	2	-	27260156	A375	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.13940059934180066	[639]	[856,724,599,552]	-2	hSpCas9	negative selection	5769319
97659378	97659401	2	-	27260156	A375	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.805927447674528	[88]	[238,191,243,66]	9	hSpCas9	negative selection	5769320
97659418	97659441	2	-	27260156	A375	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.4673137245996807	[189]	[338,354,370,182]	6	hSpCas9	negative selection	5833601
97658905	97658928	2	+	27260156	A375	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.13447307771219408	[142]	[102,193,168,147]	-2	hSpCas9	negative selection	5833602
97661924	97661947	2	-	27260156	A375	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.41449819141570554	[154]	[88,220,151,96]	-5	hSpCas9	negative selection	5833603
97660622	97660645	2	-	27260156	COLO741	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.2358050557406064	[55]	[77,74,97]	5	hSpCas9	negative selection	5890569
97658956	97658979	2	-	27260156	COLO741	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.2740046261440858	[639]	[809,699,538]	-5	hSpCas9	negative selection	5890570
97659378	97659401	2	-	27260156	COLO741	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.31968089604720973	[88]	[166,166,96]	6	hSpCas9	negative selection	5890571
97659418	97659441	2	-	27260156	COLO741	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.42216821131733195	[189]	[308,425,244]	8	hSpCas9	negative selection	5954852
97658905	97658928	2	+	27260156	COLO741	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.2545964284455866	[142]	[285,195,179]	5	hSpCas9	negative selection	5954853
97661924	97661947	2	-	27260156	COLO741	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-1.1199320292215855	[154]	[116,48,107]	-9	hSpCas9	negative selection	5954854
97660622	97660645	2	-	27260156	CAL120	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.25166560451333586	[55]	[10,141,84]	4	hSpCas9	negative selection	6011820
97658956	97658979	2	-	27260156	CAL120	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.5219303083205236	[639]	[709,584,394]	-6	hSpCas9	negative selection	6011821
97659378	97659401	2	-	27260156	CAL120	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.1164039967524646	[88]	[249,27,101]	1	hSpCas9	negative selection	6011822
97659418	97659441	2	-	27260156	CAL120	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.16860127385082446	[189]	[260,190,342]	2	hSpCas9	negative selection	6076103
97658905	97658928	2	+	27260156	CAL120	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.07268546644352303	[142]	[222,114,227]	1	hSpCas9	negative selection	6076104
97661924	97661947	2	-	27260156	CAL120	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	0.22910009316024804	[154]	[115,63,476]	3	hSpCas9	negative selection	6076105
97660622	97660645	2	-	27260156	CADOES1	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.5978485449743247	[55]	[175,41,17,78]	8	hSpCas9	negative selection	6133071
97658956	97658979	2	-	27260156	CADOES1	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.23905380476423294	[639]	[564,627,358,463]	-4	hSpCas9	negative selection	6133072
97659378	97659401	2	-	27260156	CADOES1	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.477556922580638	[88]	[94,52,47,40]	-7	hSpCas9	negative selection	6133073
97659418	97659441	2	-	27260156	CADOES1	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.251454661309078	[189]	[197,187,229,225]	4	hSpCas9	negative selection	6197354
97658905	97658928	2	+	27260156	CADOES1	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.29434226232369065	[142]	[100,148,124,281]	5	hSpCas9	negative selection	6197355
97661924	97661947	2	-	27260156	CADOES1	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.4832387842149699	[154]	[141,53,69,147]	-7	hSpCas9	negative selection	6197356
97660622	97660645	2	-	27260156	EWS502	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.5548246345368404	[55]	[65,102,16,168]	8	hSpCas9	negative selection	6254322
97658956	97658979	2	-	27260156	EWS502	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.6616010473957608	[639]	[339,500,363,520]	-8	hSpCas9	negative selection	6254323
97659378	97659401	2	-	27260156	EWS502	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.27140993015181447	[88]	[67,124,69,45]	-5	hSpCas9	negative selection	6254324
97659418	97659441	2	-	27260156	EWS502	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.17715623570339312	[189]	[138,266,288,223]	3	hSpCas9	negative selection	6318605
97658905	97658928	2	+	27260156	EWS502	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.15907748231407792	[142]	[217,133,214,99]	2	hSpCas9	negative selection	6318606
97661924	97661947	2	-	27260156	EWS502	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.37557451027700917	[154]	[81,91,111,233]	-6	hSpCas9	negative selection	6318607
97660622	97660645	2	-	27260156	EW8	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.437921203155867	[55]	[136,38,37,43]	7	hSpCas9	negative selection	6375573
97658956	97658979	2	-	27260156	EW8	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.4802012471145921	[639]	[347,439,287,421]	-7	hSpCas9	negative selection	6375574
97659378	97659401	2	-	27260156	EW8	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.5389567828174693	[88]	[22,67,58,43]	-7	hSpCas9	negative selection	6375575
97659418	97659441	2	-	27260156	EW8	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.0057313192541634805	[189]	[276,125,97,134]	0	hSpCas9	negative selection	6439856
97658905	97658928	2	+	27260156	EW8	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.1774662000711118	[142]	[111,146,135,125]	3	hSpCas9	negative selection	6439857
97661924	97661947	2	-	27260156	EW8	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-1.0265638088497315	[154]	[68,30,91,49]	-9	hSpCas9	negative selection	6439858
97660622	97660645	2	-	27260156	CORL105	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	1.340112465130778	[55]	[208,104,231,130]	9	hSpCas9	negative selection	6496824
97658956	97658979	2	-	27260156	CORL105	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.13865208103749777	[639]	[718,565,740,708]	-3	hSpCas9	negative selection	6496825
97659378	97659401	2	-	27260156	CORL105	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.0852215089443562	[88]	[121,125,89,100]	1	hSpCas9	negative selection	6496826
97659418	97659441	2	-	27260156	CORL105	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.11185268215401556	[189]	[210,302,194,242]	2	hSpCas9	negative selection	6561107
97658905	97658928	2	+	27260156	CORL105	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.12098804864266466	[142]	[241,139,126,105]	-2	hSpCas9	negative selection	6561108
97661924	97661947	2	-	27260156	CORL105	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.7796860214496015	[154]	[65,86,114,154]	-8	hSpCas9	negative selection	6561109
97660622	97660645	2	-	27260156	HS294T	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	-0.001099231292094771	[55]	[15,23,29,15]	0	hSpCas9	negative selection	6618075
97658956	97658979	2	-	27260156	HS294T	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.4152217223200719	[639]	[155,207,172,210]	-5	hSpCas9	negative selection	6618076
97659378	97659401	2	-	27260156	HS294T	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.7818233658072264	[88]	[64,30,100,35]	8	hSpCas9	negative selection	6618077
97659418	97659441	2	-	27260156	HS294T	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.46525752824804223	[189]	[66,51,40,50]	-6	hSpCas9	negative selection	6682358
97658905	97658928	2	+	27260156	HS294T	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.8948168786184667	[142]	[124,80,87,117]	9	hSpCas9	negative selection	6682359
97661924	97661947	2	-	27260156	HS294T	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.5292930569586298	[154]	[22,70,29,42]	-6	hSpCas9	negative selection	6682360
97660622	97660645	2	-	27260156	HCC44	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.4664406893637034	[55]	[78,90,152,37]	7	hSpCas9	negative selection	6739326
97658956	97658979	2	-	27260156	HCC44	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.29685581657554966	[639]	[379,374,716,902]	-5	hSpCas9	negative selection	6739327
97659378	97659401	2	-	27260156	HCC44	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.8002751591885642	[88]	[15,52,121,47]	-8	hSpCas9	negative selection	6739328
97659418	97659441	2	-	27260156	HCC44	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.1362775596516792	[189]	[315,199,314,140]	2	hSpCas9	negative selection	6803609
97658905	97658928	2	+	27260156	HCC44	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.23378459446277988	[142]	[195,78,125,158]	-4	hSpCas9	negative selection	6803610
97661924	97661947	2	-	27260156	HCC44	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.8652008878745705	[154]	[78,54,103,149]	-8	hSpCas9	negative selection	6803611
97660622	97660645	2	-	27260156	G402	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	-0.12000672742578544	[55]	[68,8,22,143]	-1	hSpCas9	negative selection	6860577
97658956	97658979	2	-	27260156	G402	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.17926321961550373	[639]	[894,587,526,765]	-2	hSpCas9	negative selection	6860578
97659378	97659401	2	-	27260156	G402	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.4313935989882651	[88]	[503,32,25,70]	5	hSpCas9	negative selection	6860579
97659418	97659441	2	-	27260156	G402	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.1133092878924069	[189]	[108,414,94,232]	-1	hSpCas9	negative selection	6924860
97658905	97658928	2	+	27260156	G402	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.4573774877231336	[142]	[195,58,92,163]	-5	hSpCas9	negative selection	6924861
97661924	97661947	2	-	27260156	G402	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.864670676330825	[154]	[141,198,63,24]	-7	hSpCas9	negative selection	6924862
97660622	97660645	2	-	27260156	L33	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.7618980719059185	[55]	[90,45,42,107]	9	hSpCas9	negative selection	6981828
97658956	97658979	2	-	27260156	L33	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.1369724937314239	[639]	[538,213,417,602]	-3	hSpCas9	negative selection	6981829
97659378	97659401	2	-	27260156	L33	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.18821647747231518	[88]	[118,41,56,92]	4	hSpCas9	negative selection	6981830
97659418	97659441	2	-	27260156	L33	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.4751514855966912	[189]	[123,56,85,146]	-8	hSpCas9	negative selection	7046111
97658905	97658928	2	+	27260156	L33	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.06509790270976445	[142]	[109,87,97,118]	1	hSpCas9	negative selection	7046112
97661924	97661947	2	-	27260156	L33	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.5772734881534642	[154]	[70,36,52,169]	-8	hSpCas9	negative selection	7046113
97660622	97660645	2	-	27260156	K562	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	-0.7057532576184498	[55]	[89,4,15,15]	-7	hSpCas9	negative selection	7103079
97658956	97658979	2	-	27260156	K562	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.16899694581895186	[639]	[396,551,1164,436]	2	hSpCas9	negative selection	7103080
97659378	97659401	2	-	27260156	K562	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.10659215159970614	[88]	[70,68,119,36]	-1	hSpCas9	negative selection	7103081
97659418	97659441	2	-	27260156	K562	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.5777870826633191	[189]	[87,110,134,114]	-6	hSpCas9	negative selection	7167362
97658905	97658928	2	+	27260156	K562	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.06661547650145394	[142]	[145,177,60,105]	-1	hSpCas9	negative selection	7167363
97661924	97661947	2	-	27260156	K562	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.7945698618978652	[154]	[107,10,101,92]	-7	hSpCas9	negative selection	7167364
97660622	97660645	2	-	27260156	HT29	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.009755250348053579	[55]	[72,51,55,88]	0	hSpCas9	negative selection	7224330
97658956	97658979	2	-	27260156	HT29	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.2543547561979128	[639]	[683,597,658,659]	-5	hSpCas9	negative selection	7224331
97659378	97659401	2	-	27260156	HT29	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.21880394998941943	[88]	[137,154,94,118]	4	hSpCas9	negative selection	7224332
97659418	97659441	2	-	27260156	HT29	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.09262238824283786	[189]	[265,229,212,166]	-2	hSpCas9	negative selection	7288613
97658905	97658928	2	+	27260156	HT29	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.15452187533311967	[142]	[319,126,193,141]	3	hSpCas9	negative selection	7288614
97661924	97661947	2	-	27260156	HT29	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.016896152996619396	[154]	[239,222,147,144]	0	hSpCas9	negative selection	7288615
97660622	97660645	2	-	27260156	MHHES1	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.1430137806463163	[55]	[118,75,62,33]	2	hSpCas9	negative selection	7345581
97658956	97658979	2	-	27260156	MHHES1	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.46767498474136	[639]	[384,675,515,499]	-7	hSpCas9	negative selection	7345582
97659378	97659401	2	-	27260156	MHHES1	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.23099489989548072	[88]	[80,147,81,147]	4	hSpCas9	negative selection	7345583
97659418	97659441	2	-	27260156	MHHES1	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.11461996440415567	[189]	[280,192,104,321]	2	hSpCas9	negative selection	7409864
97658905	97658928	2	+	27260156	MHHES1	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.078708135572362	[142]	[360,192,64,98]	1	hSpCas9	negative selection	7409865
97661924	97661947	2	-	27260156	MHHES1	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.42568552883358635	[154]	[150,114,132,120]	-7	hSpCas9	negative selection	7409866
97660622	97660645	2	-	27260156	MEWO	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.6582846596305973	[55]	[101,36,112]	9	hSpCas9	negative selection	7466832
97658956	97658979	2	-	27260156	MEWO	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.5809291434861585	[639]	[523,348,351]	-8	hSpCas9	negative selection	7466833
97659378	97659401	2	-	27260156	MEWO	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.8651349109855238	[88]	[122,236,88]	9	hSpCas9	negative selection	7466834
97659418	97659441	2	-	27260156	MEWO	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.40265392433155145	[189]	[115,91,191]	-7	hSpCas9	negative selection	7531115
97658905	97658928	2	+	27260156	MEWO	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.21207800217690176	[142]	[137,78,133]	-4	hSpCas9	negative selection	7531116
97661924	97661947	2	-	27260156	MEWO	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.6676916772835462	[154]	[45,104,113]	-8	hSpCas9	negative selection	7531117
97660622	97660645	2	-	27260156	LNCAPCLONEFGC	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	1.0709540334267653	[55]	[97,104,163,67]	9	hSpCas9	negative selection	7588083
97658956	97658979	2	-	27260156	LNCAPCLONEFGC	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.20026276572477494	[639]	[437,492,570,527]	-3	hSpCas9	negative selection	7588084
97659378	97659401	2	-	27260156	LNCAPCLONEFGC	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.5928163611078019	[88]	[123,125,94,136]	8	hSpCas9	negative selection	7588085
97659418	97659441	2	-	27260156	LNCAPCLONEFGC	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.1736370107669407	[189]	[183,119,163,308]	2	hSpCas9	negative selection	7652366
97658905	97658928	2	+	27260156	LNCAPCLONEFGC	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.10535601618184409	[142]	[140,96,185,142]	1	hSpCas9	negative selection	7652367
97661924	97661947	2	-	27260156	LNCAPCLONEFGC	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.688060459289102	[154]	[69,118,81,74]	-8	hSpCas9	negative selection	7652368
97660622	97660645	2	-	27260156	PANC0327	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	1.560756278266191	[55]	[98,94,288,106]	9	hSpCas9	negative selection	7709334
97658956	97658979	2	-	27260156	PANC0327	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.06030333616578276	[639]	[412,652,521,567]	-1	hSpCas9	negative selection	7709335
97659378	97659401	2	-	27260156	PANC0327	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.8419276015717065	[88]	[155,194,83,125]	9	hSpCas9	negative selection	7709336
97659418	97659441	2	-	27260156	PANC0327	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.14116994715437703	[189]	[83,115,73,336]	-2	hSpCas9	negative selection	7773617
97658905	97658928	2	+	27260156	PANC0327	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.8089055179193353	[142]	[128,111,414,240]	9	hSpCas9	negative selection	7773618
97661924	97661947	2	-	27260156	PANC0327	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.7453027746354657	[154]	[104,84,63,75]	-7	hSpCas9	negative selection	7773619
97660622	97660645	2	-	27260156	NCIH2009	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.6274977235084291	[55]	[213,110,55]	8	hSpCas9	negative selection	7830585
97658956	97658979	2	-	27260156	NCIH2009	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.2582525708738988	[639]	[886,755,625]	-4	hSpCas9	negative selection	7830586
97659378	97659401	2	-	27260156	NCIH2009	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.24996025226115215	[88]	[147,113,181]	3	hSpCas9	negative selection	7830587
97659418	97659441	2	-	27260156	NCIH2009	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.1907639733188331	[189]	[202,204,283]	-3	hSpCas9	negative selection	7894868
97658905	97658928	2	+	27260156	NCIH2009	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.25772214114846204	[142]	[204,211,292]	3	hSpCas9	negative selection	7894869
97661924	97661947	2	-	27260156	NCIH2009	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.370493643233206	[154]	[196,171,138]	-5	hSpCas9	negative selection	7894870
97660622	97660645	2	-	27260156	NCIH1373	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.3039521964848464	[55]	[35,72,43,40]	3	hSpCas9	negative selection	7951836
97658956	97658979	2	-	27260156	NCIH1373	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.12111036186267055	[639]	[1151,501,770,204]	1	hSpCas9	negative selection	7951837
97659378	97659401	2	-	27260156	NCIH1373	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.716609989017372	[88]	[78,40,13,30]	-6	hSpCas9	negative selection	7951838
97659418	97659441	2	-	27260156	NCIH1373	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.3461937958724628	[189]	[251,333,254,59]	3	hSpCas9	negative selection	8016119
97658905	97658928	2	+	27260156	NCIH1373	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.038776599720182325	[142]	[285,49,120,52]	0	hSpCas9	negative selection	8016120
97661924	97661947	2	-	27260156	NCIH1373	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.387166782371682	[154]	[124,116,158,33]	-4	hSpCas9	negative selection	8016121
97660622	97660645	2	-	27260156	PATU8902	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.019458725734915028	[55]	[26,21,43,252]	0	hSpCas9	negative selection	8073087
97658956	97658979	2	-	27260156	PATU8902	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.13048469353909886	[639]	[435,829,956,1019]	-1	hSpCas9	negative selection	8073088
97659378	97659401	2	-	27260156	PATU8902	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.5272578554490783	[88]	[114,99,34,108]	-5	hSpCas9	negative selection	8073089
97659418	97659441	2	-	27260156	PATU8902	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.31229884930165996	[189]	[32,395,346,562]	3	hSpCas9	negative selection	8137370
97658905	97658928	2	+	27260156	PATU8902	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.40113733673801066	[142]	[122,270,127,77]	-4	hSpCas9	negative selection	8137371
97661924	97661947	2	-	27260156	PATU8902	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.509555871486854	[154]	[120,92,131,279]	-5	hSpCas9	negative selection	8137372
97660622	97660645	2	-	27260156	PANC1	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	1.3897321437351309	[55]	[100,288,103,53]	9	hSpCas9	negative selection	8194338
97658956	97658979	2	-	27260156	PANC1	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.1552529491867362	[639]	[538,497,437,490]	-3	hSpCas9	negative selection	8194339
97659378	97659401	2	-	27260156	PANC1	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.11084567660608302	[88]	[93,79,17,87]	-2	hSpCas9	negative selection	8194340
97659418	97659441	2	-	27260156	PANC1	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.11952619410986909	[189]	[189,135,188,89]	-2	hSpCas9	negative selection	8258621
97658905	97658928	2	+	27260156	PANC1	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.29064209255071605	[142]	[88,172,106,53]	-5	hSpCas9	negative selection	8258622
97661924	97661947	2	-	27260156	PANC1	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.5468072317990691	[154]	[76,109,120,63]	-7	hSpCas9	negative selection	8258623
97660622	97660645	2	-	27260156	PANC0813	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.5440393706881164	[55]	[132,104,57,90]	8	hSpCas9	negative selection	8315589
97658956	97658979	2	-	27260156	PANC0813	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.16282233302307142	[639]	[696,625,786,582]	-3	hSpCas9	negative selection	8315590
97659378	97659401	2	-	27260156	PANC0813	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.10908065210228735	[88]	[105,159,105,79]	1	hSpCas9	negative selection	8315591
97659418	97659441	2	-	27260156	PANC0813	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.1440405750917575	[189]	[205,312,183,109]	-2	hSpCas9	negative selection	8379872
97658905	97658928	2	+	27260156	PANC0813	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.000367054292348179	[142]	[193,224,164,93]	0	hSpCas9	negative selection	8379873
97661924	97661947	2	-	27260156	PANC0813	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.01349800885800323	[154]	[170,215,166,166]	0	hSpCas9	negative selection	8379874
97660622	97660645	2	-	27260156	RDES	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.3578878630013542	[55]	[38,102,123,68]	6	hSpCas9	negative selection	8436840
97658956	97658979	2	-	27260156	RDES	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.6103875057258417	[639]	[357,504,481,613]	-8	hSpCas9	negative selection	8436841
97659378	97659401	2	-	27260156	RDES	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.056006174179869195	[88]	[80,80,113,124]	-1	hSpCas9	negative selection	8436842
97659418	97659441	2	-	27260156	RDES	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.32416835824040646	[189]	[203,332,273,285]	5	hSpCas9	negative selection	8501123
97658905	97658928	2	+	27260156	RDES	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	-0.35384960407045485	[142]	[85,139,177,114]	-6	hSpCas9	negative selection	8501124
97661924	97661947	2	-	27260156	RDES	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.6665432047971098	[154]	[124,56,122,148]	-8	hSpCas9	negative selection	8501125
97660622	97660645	2	-	27260156	PC3	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	1.3446552173836672	[55]	[76,192,196,133]	9	hSpCas9	negative selection	8558091
97658956	97658979	2	-	27260156	PC3	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.49846270815573307	[639]	[346,410,573,519]	-8	hSpCas9	negative selection	8558092
97659378	97659401	2	-	27260156	PC3	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.6595940824503004	[88]	[71,222,243,71]	9	hSpCas9	negative selection	8558093
97659418	97659441	2	-	27260156	PC3	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.11979021076030438	[189]	[186,85,308,271]	2	hSpCas9	negative selection	8622374
97658905	97658928	2	+	27260156	PC3	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.38390968934303005	[142]	[109,255,317,119]	7	hSpCas9	negative selection	8622375
97661924	97661947	2	-	27260156	PC3	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.6954919703992402	[154]	[24,120,129,145]	-9	hSpCas9	negative selection	8622376
97660622	97660645	2	-	27260156	PATU8988T	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.3771772104564661	[55]	[20,108,69,85]	6	hSpCas9	negative selection	8679342
97658956	97658979	2	-	27260156	PATU8988T	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.11911558255825788	[639]	[687,823,392,383]	-2	hSpCas9	negative selection	8679343
97659378	97659401	2	-	27260156	PATU8988T	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.09955080996373322	[88]	[97,142,50,80]	1	hSpCas9	negative selection	8679344
97659418	97659441	2	-	27260156	PATU8988T	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.3503003687884728	[189]	[363,142,287,122]	6	hSpCas9	negative selection	8743625
97658905	97658928	2	+	27260156	PATU8988T	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.5374921158264352	[142]	[96,228,245,234]	8	hSpCas9	negative selection	8743626
97661924	97661947	2	-	27260156	PATU8988T	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	0.04714880225326823	[154]	[75,190,216,135]	0	hSpCas9	negative selection	8743627
97660622	97660645	2	-	27260156	T47D	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.5181981314153954	[55]	[109,91,60,111]	9	hSpCas9	negative selection	8800593
97658956	97658979	2	-	27260156	T47D	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.3954400024106466	[639]	[591,565,516,593]	-7	hSpCas9	negative selection	8800594
97659378	97659401	2	-	27260156	T47D	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.15184865685381022	[88]	[115,96,113,135]	3	hSpCas9	negative selection	8800595
97659418	97659441	2	-	27260156	T47D	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.2535967651293036	[189]	[328,220,260,247]	5	hSpCas9	negative selection	8864876
97658905	97658928	2	+	27260156	T47D	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.2340068498407628	[142]	[235,185,169,192]	5	hSpCas9	negative selection	8864877
97661924	97661947	2	-	27260156	T47D	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.2082841812367351	[154]	[169,148,148,157]	-4	hSpCas9	negative selection	8864878
97660622	97660645	2	-	27260156	SU8686	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.5054628029967332	[55]	[68,74,60,116]	8	hSpCas9	negative selection	8921844
97658956	97658979	2	-	27260156	SU8686	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.08808184892793758	[639]	[453,532,503,975]	-1	hSpCas9	negative selection	8921845
97659378	97659401	2	-	27260156	SU8686	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.25063096016637365	[88]	[121,106,83,102]	4	hSpCas9	negative selection	8921846
97659418	97659441	2	-	27260156	SU8686	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.12272722991027818	[189]	[124,170,260,290]	2	hSpCas9	negative selection	8986127
97658905	97658928	2	+	27260156	SU8686	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.25765627036435657	[142]	[97,136,240,223]	4	hSpCas9	negative selection	8986128
97661924	97661947	2	-	27260156	SU8686	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.27223101189706056	[154]	[94,82,176,170]	-4	hSpCas9	negative selection	8986129
97660622	97660645	2	-	27260156	SKES1	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.8349593149767585	[55]	[155,97,43,106]	9	hSpCas9	negative selection	9043095
97658956	97658979	2	-	27260156	SKES1	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.5785212388685842	[639]	[418,508,462,333]	-8	hSpCas9	negative selection	9043096
97659378	97659401	2	-	27260156	SKES1	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.022280605342691384	[88]	[61,175,34,83]	0	hSpCas9	negative selection	9043097
97659418	97659441	2	-	27260156	SKES1	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.09315428269181902	[189]	[167,288,237,125]	2	hSpCas9	negative selection	9107378
97658905	97658928	2	+	27260156	SKES1	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.28118145352837876	[142]	[133,155,205,185]	6	hSpCas9	negative selection	9107379
97661924	97661947	2	-	27260156	SKES1	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.9651585471211455	[154]	[113,66,42,93]	-9	hSpCas9	negative selection	9107380
97660622	97660645	2	-	27260156	TOV112D	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	1.3354180763534158	[55]	[146,149,149,121]	9	hSpCas9	negative selection	9164346
97658956	97658979	2	-	27260156	TOV112D	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.49564208630369694	[639]	[423,407,564,407]	-7	hSpCas9	negative selection	9164347
97659378	97659401	2	-	27260156	TOV112D	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.44171864652675974	[88]	[184,112,159,31]	7	hSpCas9	negative selection	9164348
97659418	97659441	2	-	27260156	TOV112D	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.2887846292187608	[189]	[269,310,175,195]	5	hSpCas9	negative selection	9228629
97658905	97658928	2	+	27260156	TOV112D	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.025675638894197217	[142]	[185,162,111,129]	0	hSpCas9	negative selection	9228630
97661924	97661947	2	-	27260156	TOV112D	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-1.0568113281867908	[154]	[64,78,56,96]	-9	hSpCas9	negative selection	9228631
97660622	97660645	2	-	27260156	TC71	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.3382743025563304	[55]	[79,96,63,61]	7	hSpCas9	negative selection	9285597
97658956	97658979	2	-	27260156	TC71	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.4619171128089095	[639]	[504,523,437,528]	-8	hSpCas9	negative selection	9285598
97659378	97659401	2	-	27260156	TC71	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	-0.020708043093637496	[88]	[84,157,61,70]	0	hSpCas9	negative selection	9285599
97659418	97659441	2	-	27260156	TC71	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	-0.019331973450050777	[189]	[206,209,157,231]	0	hSpCas9	negative selection	9349880
97658905	97658928	2	+	27260156	TC71	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.333606877044347	[142]	[190,202,214,160]	7	hSpCas9	negative selection	9349881
97661924	97661947	2	-	27260156	TC71	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.6152777886620746	[154]	[76,98,150,105]	-9	hSpCas9	negative selection	9349882
97660622	97660645	2	-	27260156	TC32	viability	TCGGGCGGCCGAAGCACATGCGG	ACTR1B	ENSG00000115073	0.5050478625798798	[55]	[69,40,67,130]	8	hSpCas9	negative selection	9406848
97658956	97658979	2	-	27260156	TC32	viability	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.2050773683068799	[639]	[496,522,590,451]	-4	hSpCas9	negative selection	9406849
97659378	97659401	2	-	27260156	TC32	viability	CTGGCAGTACGTCTACTCCAAGG	ACTR1B	ENSG00000115073	0.09142697930179766	[88]	[49,104,100,95]	1	hSpCas9	negative selection	9406850
97659418	97659441	2	-	27260156	TC32	viability	AGCACGGCGTGGTGCGAGACTGG	ACTR1B	ENSG00000115073	0.46855018990597674	[189]	[282,160,325,244]	7	hSpCas9	negative selection	9471131
97658905	97658928	2	+	27260156	TC32	viability	GAACAGGGCCGGCACGTTGAAGG	ACTR1B	ENSG00000115073	0.12137097697110422	[142]	[106,109,248,146]	2	hSpCas9	negative selection	9471132
97661924	97661947	2	-	27260156	TC32	viability	GGTTCGGGGGTGATTAAAGCTGG	ACTR1B	ENSG00000115073	-0.47171994854936017	[154]	[161,62,86,106]	-7	hSpCas9	negative selection	9471133
97657157	97657180	2	-	27869803	HPAFII	viability after 27 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.3990387506417012	[154]	[101,111,NaN]	3	hSpCas9	negative selection	9576280
97657960	97657983	2	-	27869803	HPAFII	viability after 27 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-5.464736968403057	[83]	[0,0,NaN]	-9	hSpCas9	negative selection	9576281
97658479	97658502	2	-	27869803	HPAFII	viability after 27 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	-0.9353930247026081	[124]	[65,7,NaN]	-6	hSpCas9	negative selection	9576282
97658956	97658979	2	-	27869803	HPAFII	viability after 27 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.4395758342967966	[936]	[768,583,NaN]	3	hSpCas9	negative selection	9576283
97659343	97659366	2	+	27869803	HPAFII	viability after 27 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	0.3117328634818832	[572]	[626,162,NaN]	2	hSpCas9	negative selection	9576284
97660637	97660660	2	-	27869803	HPAFII	viability after 27 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.3520649143030058	[161]	[99,38,NaN]	-3	hSpCas9	negative selection	9576285
97657157	97657180	2	-	27869803	HPAFII	viability after 15 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.014549085008782159	[154]	[286,88,NaN]	0	hSpCas9	negative selection	9658729
97657960	97657983	2	-	27869803	HPAFII	viability after 15 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.8753012538208713	[83]	[18,67,NaN]	-7	hSpCas9	negative selection	9658730
97658479	97658502	2	-	27869803	HPAFII	viability after 15 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	-0.24464808031955387	[124]	[150,89,NaN]	-3	hSpCas9	negative selection	9658731
97658956	97658979	2	-	27869803	HPAFII	viability after 15 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	-0.02569203639074047	[936]	[1484,680,NaN]	0	hSpCas9	negative selection	9658732
97659343	97659366	2	+	27869803	HPAFII	viability after 15 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.007246202567824822	[572]	[978,384,NaN]	0	hSpCas9	negative selection	9658733
97660637	97660660	2	-	27869803	HPAFII	viability after 15 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-1.16832491599432	[161]	[74,78,NaN]	-8	hSpCas9	negative selection	9658734
97657157	97657180	2	-	27869803	ASPC1	viability after 36 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.0008491307401230497	[415]	[241,51,149]	0	hSpCas9	negative selection	9741178
97657960	97657983	2	-	27869803	ASPC1	viability after 36 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	0.1718511737432198	[249]	[61,131,95]	1	hSpCas9	negative selection	9741179
97658479	97658502	2	-	27869803	ASPC1	viability after 36 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	-0.22812231345886536	[343]	[69,25,184]	-2	hSpCas9	negative selection	9741180
97658956	97658979	2	-	27869803	ASPC1	viability after 36 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.826073556139602	[1760]	[860,1624,813]	7	hSpCas9	negative selection	9741181
97659343	97659366	2	+	27869803	ASPC1	viability after 36 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	0.30054148216209065	[1757]	[956,796,573]	3	hSpCas9	negative selection	9741182
97660637	97660660	2	-	27869803	ASPC1	viability after 36 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.03965044145418439	[312]	[23,255,58]	0	hSpCas9	negative selection	9741183
97657157	97657180	2	-	27869803	PATU8988S	viability after 35 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.955599831390144	[365]	[78,72,NaN]	-7	hSpCas9	negative selection	9823627
97657960	97657983	2	-	27869803	PATU8988S	viability after 35 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.8758362720126971	[254]	[40,70,NaN]	-7	hSpCas9	negative selection	9823628
97658479	97658502	2	-	27869803	PATU8988S	viability after 35 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.9695887016995779	[330]	[286,234,NaN]	8	hSpCas9	negative selection	9823629
97658956	97658979	2	-	27869803	PATU8988S	viability after 35 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.26966927232642823	[1627]	[763,816,NaN]	3	hSpCas9	negative selection	9823630
97659343	97659366	2	+	27869803	PATU8988S	viability after 35 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.3917332679038461	[1441]	[515,368,NaN]	-4	hSpCas9	negative selection	9823631
97660637	97660660	2	-	27869803	PATU8988S	viability after 35 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	0.20842833400777605	[443]	[256,155,NaN]	2	hSpCas9	negative selection	9823632
97657157	97657180	2	-	27869803	PATU8988S	viability after 31 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.7245317845551652	[365]	[97,75,NaN]	-6	hSpCas9	negative selection	9906076
97657960	97657983	2	-	27869803	PATU8988S	viability after 31 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-0.5924525750991076	[254]	[44,95,NaN]	-6	hSpCas9	negative selection	9906077
97658479	97658502	2	-	27869803	PATU8988S	viability after 31 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	0.5669300784351288	[330]	[180,213,NaN]	6	hSpCas9	negative selection	9906078
97658956	97658979	2	-	27869803	PATU8988S	viability after 31 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.390855067527591	[1627]	[617,1147,NaN]	5	hSpCas9	negative selection	9906079
97659343	97659366	2	+	27869803	PATU8988S	viability after 31 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	-0.22596463722256388	[1441]	[433,564,NaN]	-3	hSpCas9	negative selection	9906080
97660637	97660660	2	-	27869803	PATU8988S	viability after 31 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.047324814683689265	[443]	[213,116,NaN]	0	hSpCas9	negative selection	9906081
97657157	97657180	2	-	27869803	HPAFII	viability after 35 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	-0.43163738853073763	[154]	[60,54,NaN]	-3	hSpCas9	negative selection	9988525
97657960	97657983	2	-	27869803	HPAFII	viability after 35 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-5.4102288697820855	[83]	[0,0,NaN]	-9	hSpCas9	negative selection	9988526
97658479	97658502	2	-	27869803	HPAFII	viability after 35 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	-0.7579976995746431	[124]	[51,20,NaN]	-4	hSpCas9	negative selection	9988527
97658956	97658979	2	-	27869803	HPAFII	viability after 35 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.3407781450804177	[936]	[429,792,NaN]	2	hSpCas9	negative selection	9988528
97659343	97659366	2	+	27869803	HPAFII	viability after 35 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	0.008642728249692144	[572]	[407,160,NaN]	0	hSpCas9	negative selection	9988529
97660637	97660660	2	-	27869803	HPAFII	viability after 35 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-1.2305980056281933	[161]	[49,17,NaN]	-6	hSpCas9	negative selection	9988530
97657157	97657180	2	-	27869803	HPAFII	viability after 31 days	AGGAACGGCTGTACTCCACATGG	ACTR1B	ENSG00000115073	0.35277628106183473	[154]	[112,108,NaN]	2	hSpCas9	negative selection	10070974
97657960	97657983	2	-	27869803	HPAFII	viability after 31 days	GCCAACATCGTGCTCTCAGGTGG	ACTR1B	ENSG00000115073	-4.274601311024297	[83]	[0,3,NaN]	-9	hSpCas9	negative selection	10070975
97658479	97658502	2	-	27869803	HPAFII	viability after 31 days	CGACTCCTGCTGCGCAAGGAAGG	ACTR1B	ENSG00000115073	-0.9218460990471709	[124]	[59,11,NaN]	-5	hSpCas9	negative selection	10070976
97658956	97658979	2	-	27869803	HPAFII	viability after 31 days	CGCTCAACCCGAGTAAGAACCGG	ACTR1B	ENSG00000115073	0.3440282346726109	[936]	[677,655,NaN]	2	hSpCas9	negative selection	10070977
97659343	97659366	2	+	27869803	HPAFII	viability after 31 days	CCGCCACACCTCCTCCGAGAAGG	ACTR1B	ENSG00000115073	0.08188544765805283	[572]	[459,209,NaN]	0	hSpCas9	negative selection	10070978
97660637	97660660	2	-	27869803	HPAFII	viability after 31 days	TCCGTCCTAACAGTGTCGGGCGG	ACTR1B	ENSG00000115073	-0.9657695405379356	[161]	[69,20,NaN]	-6	hSpCas9	negative selection	10070979
97658982	97659005	2	-	28162770	P31FUJ	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.3873941789894544	[390]	[600]	4	hSpCas9	negative selection	10106502
97659408	97659431	2	-	28162770	P31FUJ	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	0.9830533002517312	[157]	[366]	9	hSpCas9	negative selection	10106503
97658442	97658465	2	+	28162770	P31FUJ	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.041191413409281785	[152]	[184]	0	hSpCas9	negative selection	10106504
97659354	97659377	2	-	28162770	P31FUJ	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.3683171750708596	[434]	[197]	-7	hSpCas9	negative selection	10106505
97658940	97658963	2	-	28162770	P31FUJ	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-1.5721123775299772	[166]	[65]	-7	hSpCas9	negative selection	10106506
97658596	97658619	2	-	28162770	P31FUJ	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	-0.36350589605897254	[126]	[115]	-3	hSpCas9	negative selection	10106507
97658030	97658053	2	-	28162770	P31FUJ	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.5238869102124057	[740]	[1251]	6	hSpCas9	negative selection	10106508
97660621	97660644	2	-	28162770	P31FUJ	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	-0.4551946257508265	[286]	[245]	-4	hSpCas9	negative selection	10106509
97660599	97660622	2	-	28162770	P31FUJ	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-3.83766426257324	[72]	[5]	-9	hSpCas9	negative selection	10106510
97659441	97659464	2	-	28162770	P31FUJ	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.2873520006786794	[128]	[184]	3	hSpCas9	negative selection	10106511
97658982	97659005	2	-	28162770	TF1	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10275868
97659408	97659431	2	-	28162770	TF1	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10275869
97658442	97658465	2	+	28162770	TF1	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10275870
97659354	97659377	2	-	28162770	TF1	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10275871
97658940	97658963	2	-	28162770	TF1	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10275872
97658596	97658619	2	-	28162770	TF1	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10275873
97658030	97658053	2	-	28162770	TF1	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[666]	1	hSpCas9	negative selection	10275874
97660621	97660644	2	-	28162770	TF1	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10275875
97660599	97660622	2	-	28162770	TF1	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10275876
97659441	97659464	2	-	28162770	TF1	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10275877
97658982	97659005	2	-	28162770	SKM1	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	-0.22275497129460176	[133]	[202]	-2	hSpCas9	negative selection	10445234
97659408	97659431	2	-	28162770	SKM1	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	0.15103125437772513	[26]	[52]	1	hSpCas9	negative selection	10445235
97658442	97658465	2	+	28162770	SKM1	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.35063768811734275	[58]	[132]	3	hSpCas9	negative selection	10445236
97659354	97659377	2	-	28162770	SKM1	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-2.652076696579693	[127]	[35]	-9	hSpCas9	negative selection	10445237
97658940	97658963	2	-	28162770	SKM1	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-0.5396019673212805	[36]	[44]	-4	hSpCas9	negative selection	10445238
97658596	97658619	2	-	28162770	SKM1	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	0.991229790372268	[34]	[122]	8	hSpCas9	negative selection	10445239
97658030	97658053	2	-	28162770	SKM1	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.2988977353302078	[142]	[310]	3	hSpCas9	negative selection	10445240
97660621	97660644	2	-	28162770	SKM1	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	0.7969081346224884	[55]	[171]	7	hSpCas9	negative selection	10445241
97660599	97660622	2	-	28162770	SKM1	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-0.6964708159381465	[10]	[11]	-5	hSpCas9	negative selection	10445242
97659441	97659464	2	-	28162770	SKM1	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.2154730073966571	[18]	[38]	2	hSpCas9	negative selection	10445243
97658982	97659005	2	-	28162770	SKM1	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	-0.22275497129460176	[133]	[202]	-2	hSpCas9	negative selection	10614600
97659408	97659431	2	-	28162770	SKM1	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	0.15103125437772513	[26]	[52]	1	hSpCas9	negative selection	10614601
97658442	97658465	2	+	28162770	SKM1	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.35063768811734275	[58]	[132]	3	hSpCas9	negative selection	10614602
97659354	97659377	2	-	28162770	SKM1	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-2.652076696579693	[127]	[35]	-9	hSpCas9	negative selection	10614603
97658940	97658963	2	-	28162770	SKM1	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-0.5396019673212805	[36]	[44]	-4	hSpCas9	negative selection	10614604
97658596	97658619	2	-	28162770	SKM1	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	0.991229790372268	[34]	[122]	8	hSpCas9	negative selection	10614605
97658030	97658053	2	-	28162770	SKM1	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.2988977353302078	[142]	[310]	3	hSpCas9	negative selection	10614606
97660621	97660644	2	-	28162770	SKM1	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	0.7969081346224884	[55]	[171]	7	hSpCas9	negative selection	10614607
97660599	97660622	2	-	28162770	SKM1	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-0.6964708159381465	[10]	[11]	-5	hSpCas9	negative selection	10614608
97659441	97659464	2	-	28162770	SKM1	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.2154730073966571	[18]	[38]	2	hSpCas9	negative selection	10614609
97658982	97659005	2	-	28162770	PL21	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	-0.21865001965063124	[384]	[143]	-1	hSpCas9	negative selection	10783966
97659408	97659431	2	-	28162770	PL21	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	0.8297711645442046	[105]	[81]	7	hSpCas9	negative selection	10783967
97658442	97658465	2	+	28162770	PL21	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.9344797392487028	[219]	[182]	7	hSpCas9	negative selection	10783968
97659354	97659377	2	-	28162770	PL21	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.096317792881924	[392]	[79]	-6	hSpCas9	negative selection	10783969
97658940	97658963	2	-	28162770	PL21	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	0.43460486812634314	[118]	[69]	4	hSpCas9	negative selection	10783970
97658596	97658619	2	-	28162770	PL21	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	-0.5117349987140556	[94]	[28]	-4	hSpCas9	negative selection	10783971
97658030	97658053	2	-	28162770	PL21	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.5819009588938655	[613]	[399]	5	hSpCas9	negative selection	10783972
97660621	97660644	2	-	28162770	PL21	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	-0.8442545048691334	[164]	[39]	-5	hSpCas9	negative selection	10783973
97660599	97660622	2	-	28162770	PL21	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-3.844254504869134	[32]	[0]	-9	hSpCas9	negative selection	10783974
97659441	97659464	2	-	28162770	PL21	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	-0.6929451815941681	[103]	[27]	-5	hSpCas9	negative selection	10783975
97658982	97659005	2	-	28162770	P31FUJ	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.3873941789894544	[390]	[600]	4	hSpCas9	negative selection	10953332
97659408	97659431	2	-	28162770	P31FUJ	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	0.9830533002517312	[157]	[366]	9	hSpCas9	negative selection	10953333
97658442	97658465	2	+	28162770	P31FUJ	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.041191413409281785	[152]	[184]	0	hSpCas9	negative selection	10953334
97659354	97659377	2	-	28162770	P31FUJ	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.3683171750708596	[434]	[197]	-7	hSpCas9	negative selection	10953335
97658940	97658963	2	-	28162770	P31FUJ	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-1.5721123775299772	[166]	[65]	-7	hSpCas9	negative selection	10953336
97658596	97658619	2	-	28162770	P31FUJ	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	-0.36350589605897254	[126]	[115]	-3	hSpCas9	negative selection	10953337
97658030	97658053	2	-	28162770	P31FUJ	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.5238869102124057	[740]	[1251]	6	hSpCas9	negative selection	10953338
97660621	97660644	2	-	28162770	P31FUJ	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	-0.4551946257508265	[286]	[245]	-4	hSpCas9	negative selection	10953339
97660599	97660622	2	-	28162770	P31FUJ	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-3.83766426257324	[72]	[5]	-9	hSpCas9	negative selection	10953340
97659441	97659464	2	-	28162770	P31FUJ	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.2873520006786794	[128]	[184]	3	hSpCas9	negative selection	10953341
97658982	97659005	2	-	28162770	OCIAML5	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	-0.5752263655051726	[207]	[251]	-4	hSpCas9	negative selection	11122698
97659408	97659431	2	-	28162770	OCIAML5	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	-1.125085065270413	[115]	[95]	-6	hSpCas9	negative selection	11122699
97658442	97658465	2	+	28162770	OCIAML5	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	-0.09617124816293979	[105]	[178]	0	hSpCas9	negative selection	11122700
97659354	97659377	2	-	28162770	OCIAML5	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-2.2671040701428407	[199]	[74]	-8	hSpCas9	negative selection	11122701
97658940	97658963	2	-	28162770	OCIAML5	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-1.6843391251259305	[72]	[40]	-7	hSpCas9	negative selection	11122702
97658596	97658619	2	-	28162770	OCIAML5	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	-0.7467135707177683	[65]	[70]	-5	hSpCas9	negative selection	11122703
97658030	97658053	2	-	28162770	OCIAML5	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.30321165461391386	[329]	[734]	2	hSpCas9	negative selection	11122704
97660621	97660644	2	-	28162770	OCIAML5	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	0.36013008336656266	[141]	[328]	3	hSpCas9	negative selection	11122705
97660599	97660622	2	-	28162770	OCIAML5	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-1.3066324343294782	[36]	[26]	-6	hSpCas9	negative selection	11122706
97659441	97659464	2	-	28162770	OCIAML5	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	-0.24540899904352192	[87]	[133]	-2	hSpCas9	negative selection	11122707
97658982	97659005	2	-	28162770	EOL1	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.12582720575378437	[707]	[406]	1	hSpCas9	negative selection	11292064
97659408	97659431	2	-	28162770	EOL1	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	2.000212041502607	[129]	[273]	9	hSpCas9	negative selection	11292065
97658442	97658465	2	+	28162770	EOL1	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	-0.3869637073714893	[344]	[138]	-3	hSpCas9	negative selection	11292066
97659354	97659377	2	-	28162770	EOL1	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.2971796601063459	[722]	[154]	-7	hSpCas9	negative selection	11292067
97658940	97658963	2	-	28162770	EOL1	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-0.08243865874557255	[206]	[102]	0	hSpCas9	negative selection	11292068
97658596	97658619	2	-	28162770	EOL1	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	-0.07545222842946542	[139]	[69]	0	hSpCas9	negative selection	11292069
97658030	97658053	2	-	28162770	EOL1	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	1.2187527272104002	[640]	[785]	8	hSpCas9	negative selection	11292070
97660621	97660644	2	-	28162770	EOL1	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	0.1063860945563476	[267]	[151]	1	hSpCas9	negative selection	11292071
97660599	97660622	2	-	28162770	EOL1	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-0.8012772649904716	[42]	[12]	-5	hSpCas9	negative selection	11292072
97659441	97659464	2	-	28162770	EOL1	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	-0.30325814595227785	[177]	[75]	-2	hSpCas9	negative selection	11292073
97658982	97659005	2	-	28162770	MOLM13	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.23491220956696446	[569]	[484]	1	hSpCas9	negative selection	11461430
97659408	97659431	2	-	28162770	MOLM13	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	-0.5040962422858246	[203]	[103]	-3	hSpCas9	negative selection	11461431
97658442	97658465	2	+	28162770	MOLM13	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.5335926285954086	[278]	[291]	4	hSpCas9	negative selection	11461432
97659354	97659377	2	-	28162770	MOLM13	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.6475878358753573	[558]	[128]	-7	hSpCas9	negative selection	11461433
97658940	97658963	2	-	28162770	MOLM13	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-1.1170731191765775	[200]	[66]	-5	hSpCas9	negative selection	11461434
97658596	97658619	2	-	28162770	MOLM13	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	1.4179641562128964	[146]	[283]	9	hSpCas9	negative selection	11461435
97658030	97658053	2	-	28162770	MOLM13	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.13926663408320805	[647]	[515]	1	hSpCas9	negative selection	11461436
97660621	97660644	2	-	28162770	MOLM13	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	-0.6009494947834192	[278]	[132]	-3	hSpCas9	negative selection	11461437
97660599	97660622	2	-	28162770	MOLM13	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-4.798897159150323	[76]	[1]	-9	hSpCas9	negative selection	11461438
97659441	97659464	2	-	28162770	MOLM13	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.9008487888206851	[159]	[215]	7	hSpCas9	negative selection	11461439
97658982	97659005	2	-	28162770	HEL	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.08331142338633812	[503]	[341]	0	hSpCas9	negative selection	11630796
97659408	97659431	2	-	28162770	HEL	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	-0.2983674789460745	[143]	[74]	-2	hSpCas9	negative selection	11630797
97658442	97658465	2	+	28162770	HEL	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	-0.15945438494146835	[278]	[159]	-1	hSpCas9	negative selection	11630798
97659354	97659377	2	-	28162770	HEL	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.8916909347018063	[532]	[91]	-7	hSpCas9	negative selection	11630799
97658940	97658963	2	-	28162770	HEL	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	0.08880322689982534	[137]	[93]	0	hSpCas9	negative selection	11630800
97658596	97658619	2	-	28162770	HEL	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	0.36773178450048705	[120]	[99]	3	hSpCas9	negative selection	11630801
97658030	97658053	2	-	28162770	HEL	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.46750003066157664	[611]	[541]	4	hSpCas9	negative selection	11630802
97660621	97660644	2	-	28162770	HEL	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	0.7306115880256913	[206]	[219]	6	hSpCas9	negative selection	11630803
97660599	97660622	2	-	28162770	HEL	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	0.73706621454851	[73]	[78]	6	hSpCas9	negative selection	11630804
97659441	97659464	2	-	28162770	HEL	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.7847578368727848	[144]	[159]	6	hSpCas9	negative selection	11630805
97658982	97659005	2	-	28162770	MV411	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.15557669258855267	[307]	[288]	1	hSpCas9	negative selection	11800162
97659408	97659431	2	-	28162770	MV411	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	-0.29313083057992717	[79]	[54]	-2	hSpCas9	negative selection	11800163
97658442	97658465	2	+	28162770	MV411	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.2701576272828589	[188]	[191]	2	hSpCas9	negative selection	11800164
97659354	97659377	2	-	28162770	MV411	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-2.030949117411326	[358]	[73]	-8	hSpCas9	negative selection	11800165
97658940	97658963	2	-	28162770	MV411	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-0.35119988683545755	[105]	[69]	-3	hSpCas9	negative selection	11800166
97658596	97658619	2	-	28162770	MV411	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	0.6880101421687566	[97]	[132]	6	hSpCas9	negative selection	11800167
97658030	97658053	2	-	28162770	MV411	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.19309771655586894	[513]	[494]	1	hSpCas9	negative selection	11800168
97660621	97660644	2	-	28162770	MV411	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	-0.2339023188642234	[140]	[100]	-2	hSpCas9	negative selection	11800169
97660599	97660622	2	-	28162770	MV411	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-5.559917371274829	[55]	[0]	-9	hSpCas9	negative selection	11800170
97659441	97659464	2	-	28162770	MV411	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.030626161709627064	[85]	[73]	0	hSpCas9	negative selection	11800171
97658982	97659005	2	-	28162770	MONOMAC1	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.3666949756104776	[250]	[370]	3	hSpCas9	negative selection	11969528
97659408	97659431	2	-	28162770	MONOMAC1	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	1.2025706116496842	[46]	[123]	9	hSpCas9	negative selection	11969529
97658442	97658465	2	+	28162770	MONOMAC1	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.4846016730732764	[100]	[161]	5	hSpCas9	negative selection	11969530
97659354	97659377	2	-	28162770	MONOMAC1	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-0.9156239119109051	[259]	[157]	-6	hSpCas9	negative selection	11969531
97658940	97658963	2	-	28162770	MONOMAC1	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	1.9184403703603823	[65]	[285]	9	hSpCas9	negative selection	11969532
97658596	97658619	2	-	28162770	MONOMAC1	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	0.8240247684682759	[67]	[137]	7	hSpCas9	negative selection	11969533
97658030	97658053	2	-	28162770	MONOMAC1	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.2601701064632298	[353]	[485]	2	hSpCas9	negative selection	11969534
97660621	97660644	2	-	28162770	MONOMAC1	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	0.7587633490299113	[115]	[224]	7	hSpCas9	negative selection	11969535
97660599	97660622	2	-	28162770	MONOMAC1	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	-2.4340760443604026	[32]	[6]	-9	hSpCas9	negative selection	11969536
97659441	97659464	2	-	28162770	MONOMAC1	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.9835353985822675	[44]	[101]	8	hSpCas9	negative selection	11969537
97658982	97659005	2	-	28162770	OCIAML2	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	-0.6553697050992111	[103]	[365]	-5	hSpCas9	negative selection	12138894
97659408	97659431	2	-	28162770	OCIAML2	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	0.17047575351652888	[20]	[130]	1	hSpCas9	negative selection	12138895
97658442	97658465	2	+	28162770	OCIAML2	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.11903967815652261	[50]	[306]	1	hSpCas9	negative selection	12138896
97659354	97659377	2	-	28162770	OCIAML2	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-2.121295573014147	[72]	[92]	-8	hSpCas9	negative selection	12138897
97658940	97658963	2	-	28162770	OCIAML2	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	-1.4957208062049916	[28]	[56]	-7	hSpCas9	negative selection	12138898
97658596	97658619	2	-	28162770	OCIAML2	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	-0.43820834754978355	[21]	[89]	-3	hSpCas9	negative selection	12138899
97658030	97658053	2	-	28162770	OCIAML2	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.9872579783297992	[84]	[933]	8	hSpCas9	negative selection	12138900
97660621	97660644	2	-	28162770	OCIAML2	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	-0.3747054052436257	[39]	[170]	-3	hSpCas9	negative selection	12138901
97660599	97660622	2	-	28162770	OCIAML2	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	0.9216875975365992	[1]	[20]	8	hSpCas9	negative selection	12138902
97659441	97659464	2	-	28162770	OCIAML2	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.4469080145658658	[17]	[135]	4	hSpCas9	negative selection	12138903
97658982	97659005	2	-	28162770	OCIAML3	viability	GCATCCTGTGCTCCTCACGGAGG	ACTR1B	ENSG00000115073	0.4255830880337177	[127]	[518]	4	hSpCas9	negative selection	12308260
97659408	97659431	2	-	28162770	OCIAML3	viability	GGTGCGAGACTGGAACGACATGG	ACTR1B	ENSG00000115073	-0.1910429733458944	[44]	[118]	-1	hSpCas9	negative selection	12308261
97658442	97658465	2	+	28162770	OCIAML3	viability	GACAACCTCAAACTCAGCCGAGG	ACTR1B	ENSG00000115073	0.31745568507417943	[41]	[157]	3	hSpCas9	negative selection	12308262
97659354	97659377	2	-	28162770	OCIAML3	viability	TCAGCTGCAGACCTTCTCGGAGG	ACTR1B	ENSG00000115073	-1.7885106644871418	[110]	[96]	-8	hSpCas9	negative selection	12308263
97658940	97658963	2	-	28162770	OCIAML3	viability	GAACCGGGAGAAGGCGGCAGAGG	ACTR1B	ENSG00000115073	0.03986446087793949	[28]	[89]	0	hSpCas9	negative selection	12308264
97658596	97658619	2	-	28162770	OCIAML3	viability	GTGGTTCTAGACTCAGGGGACGG	ACTR1B	ENSG00000115073	0.4188164000334206	[27]	[112]	4	hSpCas9	negative selection	12308265
97658030	97658053	2	-	28162770	OCIAML3	viability	TGAGGGGCTCCATGAGGTGGTGG	ACTR1B	ENSG00000115073	0.32462480882384726	[154]	[585]	3	hSpCas9	negative selection	12308266
97660621	97660644	2	-	28162770	OCIAML3	viability	CGGGCGGCCGAAGCACATGCGGG	ACTR1B	ENSG00000115073	0.873860815461774	[61]	[342]	7	hSpCas9	negative selection	12308267
97660599	97660622	2	-	28162770	OCIAML3	viability	GTGATGGCTGGAGCCCTGGAGGG	ACTR1B	ENSG00000115073	0.6454582943712263	[17]	[84]	6	hSpCas9	negative selection	12308268
97659441	97659464	2	-	28162770	OCIAML3	viability	GCTGACCATCCGCTACCCCATGG	ACTR1B	ENSG00000115073	0.3494088313094693	[25]	[99]	3	hSpCas9	negative selection	12308269