Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10097
• Symbol:ACTR2
• Description:actin related protein 2

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTR2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
65227936	65227959	2	+	26472758	Jiyoye	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-0.007862117772970745	[27]	[20]	0	hSpCas9	negative selection	2190
65268614	65268637	2	-	26472758	Jiyoye	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-1.343797070654212	[137]	[40]	-7	hSpCas9	negative selection	2191
65227901	65227924	2	+	26472758	Jiyoye	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	0.19567127631216152	[43]	[37]	1	hSpCas9	negative selection	2192
65265101	65265124	2	-	26472758	Jiyoye	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	0.013060655590850123	[250]	[190]	0	hSpCas9	negative selection	2193
65261255	65261278	2	+	26472758	Jiyoye	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-0.4553210947441917	[339]	[186]	-3	hSpCas9	negative selection	2194
65239843	65239866	2	+	26472758	Jiyoye	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	0.2534659661104204	[187]	[168]	2	hSpCas9	negative selection	2195
65261235	65261258	2	+	26472758	Jiyoye	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-2.7493291041741172	[106]	[11]	-9	hSpCas9	negative selection	2196
65265091	65265114	2	+	26472758	Jiyoye	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-1.2481764471066805	[62]	[19]	-7	hSpCas9	negative selection	2197
65268588	65268611	2	-	26472758	Jiyoye	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.07624909275322042	[143]	[102]	0	hSpCas9	negative selection	2198
65268575	65268598	2	-	26472758	Jiyoye	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.13339299985682923	[159]	[109]	-1	hSpCas9	negative selection	2199
65227936	65227959	2	+	26472758	KBM7	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-2.133979819509581	[125,175]	[15,16]	-8	hSpCas9	negative selection	193308
65268614	65268637	2	-	26472758	KBM7	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-0.2691516926249716	[393,358]	[157,136]	-3	hSpCas9	negative selection	193309
65227901	65227924	2	+	26472758	KBM7	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.7736167508787442	[207,189]	[68,41]	-6	hSpCas9	negative selection	193310
65265101	65265124	2	-	26472758	KBM7	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-1.2165492386150487	[1798,1190]	[322,274]	-7	hSpCas9	negative selection	193311
65261255	65261278	2	+	26472758	KBM7	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-0.988971796600604	[2151,1657]	[607,303]	-6	hSpCas9	negative selection	193312
65239843	65239866	2	+	26472758	KBM7	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.3311422467131284	[1276,682]	[399,317]	-3	hSpCas9	negative selection	193313
65261235	65261258	2	+	26472758	KBM7	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-0.7067549694992671	[337,236]	[114,51]	-5	hSpCas9	negative selection	193314
65265091	65265114	2	+	26472758	KBM7	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-1.2339926563409171	[163,221]	[41,36]	-7	hSpCas9	negative selection	193315
65268588	65268611	2	-	26472758	KBM7	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	0.33689325876906046	[471,247]	[131,275]	3	hSpCas9	negative selection	193316
65268575	65268598	2	-	26472758	KBM7	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.7855396668130925	[602,637]	[140,196]	-6	hSpCas9	negative selection	193317
65227936	65227959	2	+	26472758	Raji	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-3.477578965347557	[47]	[0]	-9	hSpCas9	negative selection	384426
65268614	65268637	2	-	26472758	Raji	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-1.3255758719025068	[215]	[19]	-7	hSpCas9	negative selection	384427
65227901	65227924	2	+	26472758	Raji	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-1.3737431543630167	[66]	[5]	-7	hSpCas9	negative selection	384428
65265101	65265124	2	-	26472758	Raji	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-2.50029904184764	[511]	[20]	-9	hSpCas9	negative selection	384429
65261255	65261278	2	+	26472758	Raji	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-1.713160158440545	[988]	[69]	-8	hSpCas9	negative selection	384430
65239843	65239866	2	+	26472758	Raji	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.8727169071886954	[575]	[72]	-6	hSpCas9	negative selection	384431
65261235	65261258	2	+	26472758	Raji	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-0.6601703786260295	[142]	[20]	-5	hSpCas9	negative selection	384432
65265091	65265114	2	+	26472758	Raji	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-0.9250379423187778	[89]	[10]	-6	hSpCas9	negative selection	384433
65268588	65268611	2	-	26472758	Raji	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-1.9297057833616205	[196]	[11]	-8	hSpCas9	negative selection	384434
65268575	65268598	2	-	26472758	Raji	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-2.4735659028409334	[358]	[14]	-9	hSpCas9	negative selection	384435
65227936	65227959	2	+	26472758	K562	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-0.7903466904942298	[83]	[40]	-5	hSpCas9	negative selection	575544
65268614	65268637	2	-	26472758	K562	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-0.4094911267722008	[224]	[142]	-3	hSpCas9	negative selection	575545
65227901	65227924	2	+	26472758	K562	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	1.2783660595897848	[83]	[171]	9	hSpCas9	negative selection	575546
65265101	65265124	2	-	26472758	K562	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-0.5775829703555587	[1088]	[615]	-4	hSpCas9	negative selection	575547
65261255	65261278	2	+	26472758	K562	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-0.611351885395305	[1711]	[945]	-4	hSpCas9	negative selection	575548
65239843	65239866	2	+	26472758	K562	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	0.6300457965255842	[668]	[873]	5	hSpCas9	negative selection	575549
65261235	65261258	2	+	26472758	K562	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-1.333010100369302	[190]	[63]	-6	hSpCas9	negative selection	575550
65265091	65265114	2	+	26472758	K562	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-1.3505278616273313	[144]	[47]	-6	hSpCas9	negative selection	575551
65268588	65268611	2	-	26472758	K562	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.10921822694825378	[298]	[233]	0	hSpCas9	negative selection	575552
65268575	65268598	2	-	26472758	K562	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.12130792094366338	[718]	[557]	-1	hSpCas9	negative selection	575553
65248354	65248377	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACACCACTGCATTCCAGCCTGG	ACTR2	ENSG00000138071	0.5914306786217665	[214,131]	[58,55]	2	dCas9-VP64	positive selection	2387217
65228867	65228890	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTAGGAGTTCGAGACCAGCCCAG	ACTR2	ENSG00000138071	-0.8844378867613548	[237,84]	[20,15]	-5	dCas9-VP64	positive selection	2461527
65248170	65248193	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGGGCGGATCACGAGGTCAAG	ACTR2	ENSG00000138071	2.37985785728498	[230,76]	[300,38]	7	dCas9-VP64	positive selection	2475681
65248354	65248377	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACACCACTGCATTCCAGCCTGG	ACTR2	ENSG00000138071	-0.37747874830615435	[626,633]	[195,122]	-4	dCas9-VP64	positive selection	2482472
65228867	65228890	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTAGGAGTTCGAGACCAGCCCAG	ACTR2	ENSG00000138071	2.6650986342381273	[238,153]	[58,738]	9	dCas9-VP64	positive selection	2556782
65248170	65248193	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGGGCGGATCACGAGGTCAAG	ACTR2	ENSG00000138071	0.17249846111827716	[159,84]	[44,44]	1	dCas9-VP64	positive selection	2570936
65246611	65246634	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATGACATGAAACACCTGTGGG	ACTR2	ENSG00000138071	-0.03262220460334833	[2,2]	[1,2]	0	hSpCas9	positive selection	2968750
65227902	65227925	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	0.029416843551930555	[3,2]	[2,1]	0	hSpCas9	positive selection	2968751
65227937	65227960	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-0.497937389113674	[1,2]	[1,0]	-6	hSpCas9	positive selection	2968752
65253743	65253766	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGTGGTAGACTCTGGAGATGG	ACTR2	ENSG00000138071	-0.8747616932267197	[1,2]	[1,0]	-8	hSpCas9	positive selection	2968753
65246611	65246634	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATGACATGAAACACCTGTGGG	ACTR2	ENSG00000138071	0.04530599268635219	[2,2]	[0,2]	0	hSpCas9	positive selection	3036608
65227902	65227925	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.24138166820732396	[3,3]	[2,1]	-4	hSpCas9	positive selection	3036609
65227937	65227960	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	0.6167493676302346	[1,1]	[2,1]	8	hSpCas9	positive selection	3036610
65253743	65253766	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGTGGTAGACTCTGGAGATGG	ACTR2	ENSG00000138071	0.205776966767515	[1,1]	[3,0]	3	hSpCas9	positive selection	3036611
65253843	65253866	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	2.1039977205342177	[48,21]	[0,0]	7	hSpCas9	positive selection	3335440
65239843	65239866	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	0.8309518169640069	[173,169]	[0,2]	4	hSpCas9	positive selection	3335441
65253772	65253795	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	2.349807127462799	[31,27]	[0,0]	8	hSpCas9	positive selection	3335442
65239937	65239960	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATTTCAATGTTTCCCACTTTGG	ACTR2	ENSG00000138071	0.07741712143090065	[144,144]	[0,0]	0	hSpCas9	positive selection	3354690
65251071	65251094	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	1.2349583984173806	[64,64]	[0,0]	5	hSpCas9	positive selection	3354691
65251044	65251067	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	0.47596649792117546	[109,109]	[0,0]	2	hSpCas9	positive selection	3354692
65246610	65246633	2	+	26780180	HT29	viability (Avana library 4 designs)	GGATGACATGAAACACCTGTGGG	ACTR2	ENSG00000138071	4.55793473298219	[]	[]	9	hSpCas9	negative selection	3404698
65227901	65227924	2	+	26780180	HT29	viability (Avana library 4 designs)	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	2.9579981128304	[]	[]	8	hSpCas9	negative selection	3404699
65227936	65227959	2	+	26780180	HT29	viability (Avana library 4 designs)	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	3.98502229400816	[]	[]	9	hSpCas9	negative selection	3404700
65253742	65253765	2	+	26780180	HT29	viability (Avana library 4 designs)	GTAGTGGTAGACTCTGGAGATGG	ACTR2	ENSG00000138071	5.16976744989654	[]	[]	9	hSpCas9	negative selection	3404701
65227936	65227959	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-11.896540901282	[]	[]	-8	hSpCas9	negative selection	3476363
65246610	65246633	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGACATGAAACACCTGTGGG	ACTR2	ENSG00000138071	-16.0535882864314	[]	[]	-9	hSpCas9	negative selection	3476364
65253742	65253765	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGTGGTAGACTCTGGAGATGG	ACTR2	ENSG00000138071	-12.6635824897174	[]	[]	-8	hSpCas9	negative selection	3476365
65227901	65227924	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-1.69535894517889	[]	[]	-2	hSpCas9	negative selection	3476366
65253804	65253827	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGTCTCCTGGTAAGATGAGGG	ACTR2	ENSG00000138071	-10.8139008989217	[]	[]	-8	hSpCas9	negative selection	3476367
65246565	65246588	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-12.2867288964444	[]	[]	-8	hSpCas9	negative selection	3476368
65227936	65227959	2	+	26780180	A375	viability (Avana lentiGuide)	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	27.6303985469126	[]	[]	9	hSpCas9	negative selection	3585022
65246610	65246633	2	+	26780180	A375	viability (Avana lentiGuide)	GGATGACATGAAACACCTGTGGG	ACTR2	ENSG00000138071	24.8718150157186	[]	[]	9	hSpCas9	negative selection	3585023
65253742	65253765	2	+	26780180	A375	viability (Avana lentiGuide)	GTAGTGGTAGACTCTGGAGATGG	ACTR2	ENSG00000138071	16.500900122837	[]	[]	8	hSpCas9	negative selection	3585024
65227901	65227924	2	+	26780180	A375	viability (Avana lentiGuide)	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	12.9046056038593	[]	[]	7	hSpCas9	negative selection	3585025
65253804	65253827	2	-	26780180	A375	viability (Avana lentiGuide)	CCAGTCTCCTGGTAAGATGAGGG	ACTR2	ENSG00000138071	33.1893317550694	[]	[]	9	hSpCas9	negative selection	3585026
65246565	65246588	2	+	26780180	A375	viability (Avana lentiGuide)	GTTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	14.8166518606383	[]	[]	8	hSpCas9	negative selection	3585027
65227936	65227959	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-0.8670235664963714	[4]	[1,2]	-8	hSpCas9	positive selection	3693681
65246610	65246633	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGACATGAAACACCTGTGGG	ACTR2	ENSG00000138071	-1.2675157652264104	[4]	[1,1]	-9	hSpCas9	positive selection	3693682
65253742	65253765	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGTGGTAGACTCTGGAGATGG	ACTR2	ENSG00000138071	-0.6592448818165177	[5]	[2,2]	-7	hSpCas9	positive selection	3693683
65227901	65227924	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	0.08415704582716099	[4]	[4,4]	2	hSpCas9	positive selection	3693684
65253804	65253827	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGTCTCCTGGTAAGATGAGGG	ACTR2	ENSG00000138071	-0.41821802113880524	[4]	[3,3]	-6	hSpCas9	positive selection	3693685
65246565	65246588	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-0.9311463979199925	[7]	[3,2]	-8	hSpCas9	positive selection	3693686
65227936	65227959	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-1.0456000074093437	[5]	[0,2]	-8	hSpCas9	positive selection	3802288
65246610	65246633	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGACATGAAACACCTGTGGG	ACTR2	ENSG00000138071	-1.1232078399961467	[5]	[2,0]	-8	hSpCas9	positive selection	3802289
65253742	65253765	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGTGGTAGACTCTGGAGATGG	ACTR2	ENSG00000138071	-1.237350750532317	[4]	[0,1]	-9	hSpCas9	positive selection	3802290
65227901	65227924	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	0.0019048302655692295	[4]	[3,4]	0	hSpCas9	positive selection	3802291
65253804	65253827	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGTCTCCTGGTAAGATGAGGG	ACTR2	ENSG00000138071	-1.7771816942219287	[5]	[0,1]	-9	hSpCas9	positive selection	3802292
65246565	65246588	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-0.08914284193113936	[4]	[3,3]	-1	hSpCas9	positive selection	3802293
65253772	65253795	2	+	26780180	A375	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	1.65203780819344	[]	[]	8	hSpCas9	negative selection	3910895
65251071	65251094	2	-	26780180	A375	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	1.67747311162155	[]	[]	9	hSpCas9	negative selection	3910896
65253843	65253866	2	+	26780180	A375	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	1.16817097410918	[]	[]	6	hSpCas9	negative selection	3910897
65239843	65239866	2	+	26780180	A375	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	1.63697628195012	[]	[]	8	hSpCas9	negative selection	3910898
65253772	65253795	2	+	26780180	HT29	viability (GeCKOv2 library)	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	1.60719082329117	[]	[]	8	hSpCas9	negative selection	4018861
65251071	65251094	2	-	26780180	HT29	viability (GeCKOv2 library)	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	1.99328471511506	[]	[]	9	hSpCas9	negative selection	4018862
65253843	65253866	2	+	26780180	HT29	viability (GeCKOv2 library)	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	2.06569044756916	[]	[]	9	hSpCas9	negative selection	4018863
65239843	65239866	2	+	26780180	HT29	viability (GeCKOv2 library)	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	1.16840317958948	[]	[]	5	hSpCas9	negative selection	4018864
65253843	65253866	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.30759987934984273	[2]	[1,0]	-6	hSpCas9	positive selection	4254359
65239843	65239866	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	0.20292344747247262	[3]	[3,2]	4	hSpCas9	positive selection	4254360
65253772	65253795	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	0.11256754110690809	[2]	[1,1]	2	hSpCas9	positive selection	4254361
65251071	65251094	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.5108636120132091	[2]	[1,0]	-8	hSpCas9	positive selection	4318643
65246566	65246588	2	+	27760321	OCIAML3	viability	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-2.323069647887925	[7,4]	[0,0]	-9	hSpCas9	negative selection	4375936
65246589	65246611	2	+	27760321	OCIAML3	viability	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-4.791540563542689	[37,32]	[0,0]	-9	hSpCas9	negative selection	4375937
65251044	65251066	2	-	27760321	OCIAML3	viability	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-4.77472138941293	[42,27]	[0,0]	-9	hSpCas9	negative selection	4375938
65251083	65251105	2	+	27760321	OCIAML3	viability	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-1.765316425702215	[419,385]	[93,90]	-8	hSpCas9	negative selection	4375939
65253737	65253759	2	+	27760321	OCIAML3	viability	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-1.3652040289383254	[313,275]	[81,98]	-8	hSpCas9	negative selection	4375940
65246566	65246588	2	+	27760321	OCIAML2	viability	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	0.7914431786395699	[7,4]	[14,0]	9	hSpCas9	negative selection	4459399
65246589	65246611	2	+	27760321	OCIAML2	viability	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-0.9053349094069874	[37,32]	[13,16]	-7	hSpCas9	negative selection	4459400
65251044	65251066	2	-	27760321	OCIAML2	viability	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-1.2626503412885257	[42,27]	[19,0]	-8	hSpCas9	negative selection	4459401
65251083	65251105	2	+	27760321	OCIAML2	viability	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-1.6305201218608316	[419,385]	[106,102]	-8	hSpCas9	negative selection	4459402
65253737	65253759	2	+	27760321	OCIAML2	viability	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-2.215438924911036	[313,275]	[30,77]	-9	hSpCas9	negative selection	4459403
65246566	65246588	2	+	27760321	MV411	viability	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-2.077991078973243	[7,4]	[0,0]	-8	hSpCas9	negative selection	4542862
65246589	65246611	2	+	27760321	MV411	viability	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-4.546461994628007	[37,32]	[0,0]	-9	hSpCas9	negative selection	4542863
65251044	65251066	2	-	27760321	MV411	viability	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-2.6045251294140264	[42,27]	[0,7]	-9	hSpCas9	negative selection	4542864
65251083	65251105	2	+	27760321	MV411	viability	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-2.4403316017118066	[419,385]	[34,69]	-9	hSpCas9	negative selection	4542865
65253737	65253759	2	+	27760321	MV411	viability	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-2.40939235548025	[313,275]	[0,89]	-9	hSpCas9	negative selection	4542866
65246566	65246588	2	+	27760321	HL60	viability	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-2.3858612407673796	[7,4]	[0,0]	-9	hSpCas9	negative selection	4626325
65246589	65246611	2	+	27760321	HL60	viability	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	0.9029009194286455	[37,32]	[56,50]	8	hSpCas9	negative selection	4626326
65251044	65251066	2	-	27760321	HL60	viability	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-4.837512982292385	[42,27]	[0,0]	-9	hSpCas9	negative selection	4626327
65251083	65251105	2	+	27760321	HL60	viability	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-2.908911695789408	[419,385]	[37,49]	-9	hSpCas9	negative selection	4626328
65253737	65253759	2	+	27760321	HL60	viability	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-3.2234282911126177	[313,275]	[33,16]	-9	hSpCas9	negative selection	4626329
65246566	65246588	2	+	27760321	HT1080	viability	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-0.8443172389209588	[4,3]	[0,0]	-4	hSpCas9	negative selection	4709788
65246589	65246611	2	+	27760321	HT1080	viability	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-3.5556706373749467	[32,25]	[0,0]	-7	hSpCas9	negative selection	4709789
65251044	65251066	2	-	27760321	HT1080	viability	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-3.3166380037395125	[27,21]	[0,0]	-7	hSpCas9	negative selection	4709790
65251083	65251105	2	+	27760321	HT1080	viability	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-7.096272455615608	[385,300]	[0,0]	-9	hSpCas9	negative selection	4709791
65253737	65253759	2	+	27760321	HT1080	viability	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-6.614942570960758	[275,215]	[0,0]	-9	hSpCas9	negative selection	4709792
65246566	65246588	2	+	27760321	HT29	viability after 7 days	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-0.2393218745670227	[4,3]	[12,1,0]	-3	hSpCas9	negative selection	4793251
65246589	65246611	2	+	27760321	HT29	viability after 7 days	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-2.314538345860912	[32,25]	[13,8,0]	-9	hSpCas9	negative selection	4793252
65251044	65251066	2	-	27760321	HT29	viability after 7 days	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-2.0293270224059934	[27,21]	[22,1,0]	-9	hSpCas9	negative selection	4793253
65251083	65251105	2	+	27760321	HT29	viability after 7 days	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-0.8657269292243079	[385,300]	[392,170,185]	-8	hSpCas9	negative selection	4793254
65253737	65253759	2	+	27760321	HT29	viability after 7 days	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-1.4871915441284278	[275,215]	[202,123,26]	-9	hSpCas9	negative selection	4793255
65246566	65246588	2	+	27760321	HT29	viability after 25 days	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-2.3639995037674826	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	4876714
65246589	65246611	2	+	27760321	HT29	viability after 25 days	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-3.828584992011657	[32,25]	[1,3,0]	-9	hSpCas9	negative selection	4876715
65251044	65251066	2	-	27760321	HT29	viability after 25 days	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-4.836320268586036	[27,21]	[0,0,0]	-9	hSpCas9	negative selection	4876716
65251083	65251105	2	+	27760321	HT29	viability after 25 days	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-3.897316030023097	[385,300]	[9,17,54]	-9	hSpCas9	negative selection	4876717
65253737	65253759	2	+	27760321	HT29	viability after 25 days	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-4.623541181699845	[275,215]	[0,3,31]	-9	hSpCas9	negative selection	4876718
65246566	65246588	2	+	27760321	HT29	viability after 22 days	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-2.381318135626742	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	4960177
65246589	65246611	2	+	27760321	HT29	viability after 22 days	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-3.2151547654143844	[32,25]	[4,0,4]	-8	hSpCas9	negative selection	4960178
65251044	65251066	2	-	27760321	HT29	viability after 22 days	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-4.853638900445295	[27,21]	[0,0,0]	-9	hSpCas9	negative selection	4960179
65251083	65251105	2	+	27760321	HT29	viability after 22 days	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-5.71092717793108	[385,300]	[0,5,15]	-9	hSpCas9	negative selection	4960180
65253737	65253759	2	+	27760321	HT29	viability after 22 days	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-5.629132564347369	[275,215]	[12,2,0]	-9	hSpCas9	negative selection	4960181
65246566	65246588	2	+	27760321	HT29	viability after 19 days	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-2.365478083203529	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5043640
65246589	65246611	2	+	27760321	HT29	viability after 19 days	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-4.139157644674959	[32,25]	[3,0,0]	-9	hSpCas9	negative selection	5043641
65251044	65251066	2	-	27760321	HT29	viability after 19 days	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-2.659207940542997	[27,21]	[0,1,9]	-8	hSpCas9	negative selection	5043642
65251083	65251105	2	+	27760321	HT29	viability after 19 days	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-3.8688658296296032	[385,300]	[77,7,0]	-9	hSpCas9	negative selection	5043643
65253737	65253759	2	+	27760321	HT29	viability after 19 days	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-5.868539716842338	[275,215]	[0,6,5]	-9	hSpCas9	negative selection	5043644
65246566	65246588	2	+	27760321	HT29	viability after 16 days	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-2.334013630782607	[4,3]	[0,0,0]	-8	hSpCas9	negative selection	5127103
65246589	65246611	2	+	27760321	HT29	viability after 16 days	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-1.6972217529495746	[32,25]	[15,13,0]	-8	hSpCas9	negative selection	5127104
65251044	65251066	2	-	27760321	HT29	viability after 16 days	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-1.2825241591220409	[27,21]	[34,0,0]	-7	hSpCas9	negative selection	5127105
65251083	65251105	2	+	27760321	HT29	viability after 16 days	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-3.1451415331472545	[385,300]	[43,18,67]	-9	hSpCas9	negative selection	5127106
65253737	65253759	2	+	27760321	HT29	viability after 16 days	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-3.3329945154251477	[275,215]	[58,24,0]	-9	hSpCas9	negative selection	5127107
65246566	65246588	2	+	27760321	HT29	viability after 13 days	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-0.935712113705522	[4,3]	[0,0,5]	-7	hSpCas9	negative selection	5210566
65246589	65246611	2	+	27760321	HT29	viability after 13 days	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-4.337835238161343	[32,25]	[0,0,2]	-9	hSpCas9	negative selection	5210567
65251044	65251066	2	-	27760321	HT29	viability after 13 days	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-2.0564180738962405	[27,21]	[0,13,5]	-8	hSpCas9	negative selection	5210568
65251083	65251105	2	+	27760321	HT29	viability after 13 days	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-1.886754069918587	[385,300]	[73,84,160]	-8	hSpCas9	negative selection	5210569
65253737	65253759	2	+	27760321	HT29	viability after 13 days	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-3.0256633456964828	[275,215]	[15,84,5]	-9	hSpCas9	negative selection	5210570
65246566	65246588	2	+	27760321	HT29	viability after 10 days	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	1.280686090379894	[4,3]	[36,2,0]	9	hSpCas9	negative selection	5294029
65246589	65246611	2	+	27760321	HT29	viability after 10 days	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-3.327316869455796	[32,25]	[8,0,0]	-9	hSpCas9	negative selection	5294030
65251044	65251066	2	-	27760321	HT29	viability after 10 days	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-1.7580388379929555	[27,21]	[9,14,2]	-9	hSpCas9	negative selection	5294031
65251083	65251105	2	+	27760321	HT29	viability after 10 days	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-0.8038538391376427	[385,300]	[211,181,338]	-7	hSpCas9	negative selection	5294032
65253737	65253759	2	+	27760321	HT29	viability after 10 days	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-1.5653325014870139	[275,215]	[60,34,210]	-8	hSpCas9	negative selection	5294033
65246566	65246588	2	+	27760321	MOLM13	viability	TTAGAAGTTAACTACCCTATGG	ACTR2	ENSG00000138071	-1.8519342661456477	[7,4]	[0,0]	-7	hSpCas9	negative selection	5377492
65246589	65246611	2	+	27760321	MOLM13	viability	AAATGGCATAGTACGAAATTGG	ACTR2	ENSG00000138071	-4.320405181800412	[37,32]	[0,0]	-9	hSpCas9	negative selection	5377493
65251044	65251066	2	-	27760321	MOLM13	viability	TACATATACACCGGAAAACTGG	ACTR2	ENSG00000138071	-4.303586007670653	[42,27]	[0,0]	-9	hSpCas9	negative selection	5377494
65251083	65251105	2	+	27760321	MOLM13	viability	GACTTTGTACGCTCAAGGTAGG	ACTR2	ENSG00000138071	-2.5459171987178393	[419,385]	[12,60]	-8	hSpCas9	negative selection	5377495
65253737	65253759	2	+	27760321	MOLM13	viability	CTGGTGTAGTGGTAGACTCTGG	ACTR2	ENSG00000138071	-2.3025221673743124	[313,275]	[64,6]	-8	hSpCas9	negative selection	5377496
65228178	65228201	2	+	27661255	K562	viability	GTGGGGGCGGCGGGCGAGACCGG	ACTR2	ENSG00000138071	0.14755397413697052	[489,632]	[520,471]	5	dCas9-KRAB	negative selection	5460767
65228190	65228213	2	+	27661255	K562	viability	GGCGAGACCGGCACTGGACATGG	ACTR2	ENSG00000138071	-0.041985470899275956	[1394,1444]	[1194,1020]	-2	dCas9-KRAB	negative selection	5460768
65228258	65228281	2	+	27661255	K562	viability	GGCAATTGGGCTAAAGCGGACGG	ACTR2	ENSG00000138071	0.0408601059677777	[557,731]	[588,474]	1	dCas9-KRAB	negative selection	5460769
65228142	65228165	2	-	27661255	K562	viability	GGGGTGGCAGGCTAAATGGGTGG	ACTR2	ENSG00000138071	0.16738213007041003	[542,602]	[552,478]	6	dCas9-KRAB	negative selection	5460770
65228215	65228238	2	-	27661255	K562	viability	GTCCCTGCCGGGCGGTCAGTAGG	ACTR2	ENSG00000138071	-0.02402867915694118	[1242,1410]	[1139,954]	-1	dCas9-KRAB	negative selection	5460771
65253843	65253866	2	+	27260156	BXPC3	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.023882167267965	[218]	[62,135,127,128]	-9	hSpCas9	negative selection	5526819
65239843	65239866	2	+	27260156	BXPC3	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.46077233716875166	[705]	[446,565,508,639]	-7	hSpCas9	negative selection	5526820
65253772	65253795	2	+	27260156	BXPC3	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.6589571377118941	[235]	[131,207,126,155]	-8	hSpCas9	negative selection	5526821
65251071	65251094	2	-	27260156	BXPC3	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.3187422217299316	[243]	[97,84,151,71]	-9	hSpCas9	negative selection	5591103
65253843	65253866	2	+	27260156	A673	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.7288037830779499	[218]	[176,156,138,163]	-9	hSpCas9	negative selection	5648070
65239843	65239866	2	+	27260156	A673	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.284576318431005	[705]	[743,676,681,684]	-6	hSpCas9	negative selection	5648071
65253772	65253795	2	+	27260156	A673	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.34952533268303987	[235]	[185,228,269,197]	-7	hSpCas9	negative selection	5648072
65251071	65251094	2	-	27260156	A673	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.6280022735735553	[243]	[168,249,194,136]	-9	hSpCas9	negative selection	5712354
65253843	65253866	2	+	27260156	A375	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.4102599438993149	[218]	[48,88,229,23]	-9	hSpCas9	negative selection	5769321
65239843	65239866	2	+	27260156	A375	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-1.0327421602405256	[705]	[453,386,329,433]	-8	hSpCas9	negative selection	5769322
65253772	65253795	2	+	27260156	A375	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-1.3361736982291759	[235]	[86,134,138,81]	-9	hSpCas9	negative selection	5769323
65251071	65251094	2	-	27260156	A375	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-2.044696475835937	[243]	[152,47,70,8]	-9	hSpCas9	negative selection	5833605
65253843	65253866	2	+	27260156	COLO741	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.0615430444990046	[218]	[113,120,162]	-9	hSpCas9	negative selection	5890572
65239843	65239866	2	+	27260156	COLO741	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.22434342616742997	[705]	[928,811,599]	-5	hSpCas9	negative selection	5890573
65253772	65253795	2	+	27260156	COLO741	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.17022135745360778	[235]	[264,240,294]	-4	hSpCas9	negative selection	5890574
65251071	65251094	2	-	27260156	COLO741	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.43121316781953656	[243]	[247,249,198]	-7	hSpCas9	negative selection	5954856
65253843	65253866	2	+	27260156	CAL120	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.7802436419290917	[218]	[234,179,73]	-8	hSpCas9	negative selection	6011823
65239843	65239866	2	+	27260156	CAL120	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-1.1381088839079694	[705]	[415,391,391]	-9	hSpCas9	negative selection	6011824
65253772	65253795	2	+	27260156	CAL120	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-1.1323041054810417	[235]	[179,106,121]	-9	hSpCas9	negative selection	6011825
65251071	65251094	2	-	27260156	CAL120	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.6744941708607541	[243]	[95,68,119]	-9	hSpCas9	negative selection	6076107
65253843	65253866	2	+	27260156	CADOES1	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.8792229522841104	[218]	[137,194,51,55]	-9	hSpCas9	negative selection	6133074
65239843	65239866	2	+	27260156	CADOES1	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	0.03695036720959277	[705]	[685,663,659,684]	0	hSpCas9	negative selection	6133075
65253772	65253795	2	+	27260156	CADOES1	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.4633627058253065	[235]	[183,106,201,142]	-7	hSpCas9	negative selection	6133076
65251071	65251094	2	-	27260156	CADOES1	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.6976567085584326	[243]	[178,158,97,122]	-8	hSpCas9	negative selection	6197358
65253843	65253866	2	+	27260156	EWS502	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.7187175401934636	[218]	[93,104,129,248]	-8	hSpCas9	negative selection	6254325
65239843	65239866	2	+	27260156	EWS502	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.2949729526612239	[705]	[684,616,526,594]	-5	hSpCas9	negative selection	6254326
65253772	65253795	2	+	27260156	EWS502	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.6653648075596366	[235]	[147,199,167,109]	-8	hSpCas9	negative selection	6254327
65251071	65251094	2	-	27260156	EWS502	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.7557073813994664	[243]	[245,93,143,115]	-8	hSpCas9	negative selection	6318609
65253843	65253866	2	+	27260156	EW8	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.26851674654163804	[218]	[256,99,116,131]	-5	hSpCas9	negative selection	6375576
65239843	65239866	2	+	27260156	EW8	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.2961870502723992	[705]	[646,432,331,492]	-5	hSpCas9	negative selection	6375577
65253772	65253795	2	+	27260156	EW8	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.16466866442242822	[235]	[357,113,126,110]	-3	hSpCas9	negative selection	6375578
65251071	65251094	2	-	27260156	EW8	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.186563992892847	[243]	[45,92,54,153]	-9	hSpCas9	negative selection	6439860
65253843	65253866	2	+	27260156	CORL105	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.8032095743799197	[218]	[151,113,250,87]	-8	hSpCas9	negative selection	6496827
65239843	65239866	2	+	27260156	CORL105	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.4164820782076214	[705]	[443,622,912,536]	-6	hSpCas9	negative selection	6496828
65253772	65253795	2	+	27260156	CORL105	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.7697722117283441	[235]	[79,111,294,179]	-8	hSpCas9	negative selection	6496829
65251071	65251094	2	-	27260156	CORL105	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.7448724354401848	[243]	[212,104,317,71]	-8	hSpCas9	negative selection	6561111
65253843	65253866	2	+	27260156	HS294T	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.854208039987908	[218]	[27,43,55,63]	-8	hSpCas9	negative selection	6618078
65239843	65239866	2	+	27260156	HS294T	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.45876866963108787	[705]	[128,183,234,263]	-6	hSpCas9	negative selection	6618079
65253772	65253795	2	+	27260156	HS294T	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.18848404090671056	[235]	[72,27,58,178]	-3	hSpCas9	negative selection	6618080
65251071	65251094	2	-	27260156	HS294T	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.8310298710808413	[243]	[72,23,45,70]	-8	hSpCas9	negative selection	6682362
65253843	65253866	2	+	27260156	HCC44	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.442993322692206	[218]	[143,49,73,102]	-9	hSpCas9	negative selection	6739329
65239843	65239866	2	+	27260156	HCC44	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-1.188199593266977	[705]	[304,266,499,359]	-9	hSpCas9	negative selection	6739330
65253772	65253795	2	+	27260156	HCC44	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.966081638221334	[235]	[195,79,243,59]	-8	hSpCas9	negative selection	6739331
65251071	65251094	2	-	27260156	HCC44	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.4623385361512269	[243]	[51,117,184,53]	-9	hSpCas9	negative selection	6803613
65253843	65253866	2	+	27260156	G402	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.9135051403720109	[218]	[292,143,33,118]	-8	hSpCas9	negative selection	6860580
65239843	65239866	2	+	27260156	G402	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.8677213953181314	[705]	[377,442,699,355]	-8	hSpCas9	negative selection	6860581
65253772	65253795	2	+	27260156	G402	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.5669014828303895	[235]	[205,54,369,141]	-6	hSpCas9	negative selection	6860582
65251071	65251094	2	-	27260156	G402	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.3320272740343193	[243]	[191,57,95,132]	-9	hSpCas9	negative selection	6924864
65253843	65253866	2	+	27260156	L33	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.14876485306226672	[218]	[206,75,81,265]	-3	hSpCas9	negative selection	6981831
65239843	65239866	2	+	27260156	L33	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.07304615593200403	[705]	[658,251,366,824]	-2	hSpCas9	negative selection	6981832
65253772	65253795	2	+	27260156	L33	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	0.076739171141606	[235]	[264,104,139,250]	1	hSpCas9	negative selection	6981833
65251071	65251094	2	-	27260156	L33	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.30339989151709124	[243]	[177,110,140,118]	-6	hSpCas9	negative selection	7046115
65253843	65253866	2	+	27260156	K562	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.690329653973501	[218]	[69,31,49,84]	-9	hSpCas9	negative selection	7103082
65239843	65239866	2	+	27260156	K562	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.7449112660981576	[705]	[385,312,497,302]	-7	hSpCas9	negative selection	7103083
65253772	65253795	2	+	27260156	K562	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.28697480726324476	[235]	[210,119,113,233]	-4	hSpCas9	negative selection	7103084
65251071	65251094	2	-	27260156	K562	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-2.1493256196280814	[243]	[9,82,73,28]	-9	hSpCas9	negative selection	7167366
65253843	65253866	2	+	27260156	HT29	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.333938042636851	[218]	[160,112,77,77]	-9	hSpCas9	negative selection	7224333
65239843	65239866	2	+	27260156	HT29	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-1.2087865023923472	[705]	[421,511,278,294]	-9	hSpCas9	negative selection	7224334
65253772	65253795	2	+	27260156	HT29	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-1.3159588077040012	[235]	[189,129,57,91]	-9	hSpCas9	negative selection	7224335
65251071	65251094	2	-	27260156	HT29	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-2.2940610066547484	[243]	[43,81,81,36]	-9	hSpCas9	negative selection	7288617
65253843	65253866	2	+	27260156	MHHES1	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.8364362821297036	[218]	[103,174,182,96]	-9	hSpCas9	negative selection	7345584
65239843	65239866	2	+	27260156	MHHES1	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.33820682873087	[705]	[899,686,509,477]	-6	hSpCas9	negative selection	7345585
65253772	65253795	2	+	27260156	MHHES1	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.5825140489466234	[235]	[146,195,253,120]	-8	hSpCas9	negative selection	7345586
65251071	65251094	2	-	27260156	MHHES1	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.0913924936134771	[243]	[219,71,137,95]	-9	hSpCas9	negative selection	7409868
65253843	65253866	2	+	27260156	MEWO	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.432837258892828	[218]	[212,186,66]	-7	hSpCas9	negative selection	7466835
65239843	65239866	2	+	27260156	MEWO	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.2311797175944556	[705]	[698,441,573]	-5	hSpCas9	negative selection	7466836
65253772	65253795	2	+	27260156	MEWO	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.7144365784707476	[235]	[196,82,135]	-9	hSpCas9	negative selection	7466837
65251071	65251094	2	-	27260156	MEWO	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.5617575364731064	[243]	[149,158,153]	-8	hSpCas9	negative selection	7531119
65253843	65253866	2	+	27260156	LNCAPCLONEFGC	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.2895900274923056	[218]	[73,112,56,74]	-9	hSpCas9	negative selection	7588086
65239843	65239866	2	+	27260156	LNCAPCLONEFGC	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.7812401112394015	[705]	[283,446,452,312]	-8	hSpCas9	negative selection	7588087
65253772	65253795	2	+	27260156	LNCAPCLONEFGC	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.46136277633221234	[235]	[142,187,127,155]	-6	hSpCas9	negative selection	7588088
65251071	65251094	2	-	27260156	LNCAPCLONEFGC	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.9550349621284735	[243]	[104,144,173,38]	-8	hSpCas9	negative selection	7652370
65253843	65253866	2	+	27260156	PANC0327	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.8792475706836906	[218]	[57,21,97,37]	-9	hSpCas9	negative selection	7709337
65239843	65239866	2	+	27260156	PANC0327	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.6956146918776851	[705]	[394,445,430,269]	-7	hSpCas9	negative selection	7709338
65253772	65253795	2	+	27260156	PANC0327	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.9266540779159929	[235]	[112,67,208,56]	-8	hSpCas9	negative selection	7709339
65251071	65251094	2	-	27260156	PANC0327	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.9526910715128167	[243]	[46,26,83,68]	-9	hSpCas9	negative selection	7773621
65253843	65253866	2	+	27260156	NCIH2009	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.3254028334802543	[218]	[95,172,90]	-8	hSpCas9	negative selection	7830588
65239843	65239866	2	+	27260156	NCIH2009	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-1.1720992953149096	[705]	[516,389,421]	-8	hSpCas9	negative selection	7830589
65253772	65253795	2	+	27260156	NCIH2009	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-1.5910156102653397	[235]	[143,108,81]	-9	hSpCas9	negative selection	7830590
65251071	65251094	2	-	27260156	NCIH2009	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.2844623353817108	[243]	[179,113,133]	-8	hSpCas9	negative selection	7894872
65253843	65253866	2	+	27260156	NCIH1373	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.772833814352238	[218]	[185,180,160,10]	-7	hSpCas9	negative selection	7951839
65239843	65239866	2	+	27260156	NCIH1373	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-1.2381611193201878	[705]	[630,160,282,86]	-8	hSpCas9	negative selection	7951840
65253772	65253795	2	+	27260156	NCIH1373	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.23023643383386538	[235]	[185,449,76,40]	-2	hSpCas9	negative selection	7951841
65251071	65251094	2	-	27260156	NCIH1373	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.7339591664635916	[243]	[65,373,80,24]	-6	hSpCas9	negative selection	8016123
65253843	65253866	2	+	27260156	PATU8902	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.6147018993366518	[218]	[66,111,149,49]	-8	hSpCas9	negative selection	8073090
65239843	65239866	2	+	27260156	PATU8902	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-1.579558706068259	[705]	[259,620,144,337]	-8	hSpCas9	negative selection	8073091
65253772	65253795	2	+	27260156	PATU8902	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-4.72016932459842	[235]	[8,14,16,6]	-9	hSpCas9	negative selection	8073092
65251071	65251094	2	-	27260156	PATU8902	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-3.0931377143522205	[243]	[103,45,5,6]	-9	hSpCas9	negative selection	8137374
65253843	65253866	2	+	27260156	PANC1	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.4660834166055527	[218]	[58,57,120,36]	-9	hSpCas9	negative selection	8194341
65239843	65239866	2	+	27260156	PANC1	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-1.0389415988457964	[705]	[262,371,203,343]	-8	hSpCas9	negative selection	8194342
65253772	65253795	2	+	27260156	PANC1	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-1.0866269362582393	[235]	[106,124,66,87]	-8	hSpCas9	negative selection	8194343
65251071	65251094	2	-	27260156	PANC1	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.3123994712826912	[243]	[18,95,58,153]	-9	hSpCas9	negative selection	8258625
65253843	65253866	2	+	27260156	PANC0813	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.6975931222470051	[218]	[100,164,116,240]	-7	hSpCas9	negative selection	8315592
65239843	65239866	2	+	27260156	PANC0813	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.38427656228236534	[705]	[570,583,554,813]	-5	hSpCas9	negative selection	8315593
65253772	65253795	2	+	27260156	PANC0813	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.8907687291707154	[235]	[131,122,167,171]	-8	hSpCas9	negative selection	8315594
65251071	65251094	2	-	27260156	PANC0813	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.1996185622685522	[243]	[147,204,81,68]	-9	hSpCas9	negative selection	8379876
65253843	65253866	2	+	27260156	RDES	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.8412109472408988	[218]	[123,156,119,160]	-8	hSpCas9	negative selection	8436843
65239843	65239866	2	+	27260156	RDES	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.05357051239564514	[705]	[642,592,978,976]	-1	hSpCas9	negative selection	8436844
65253772	65253795	2	+	27260156	RDES	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.6188207736947722	[235]	[131,158,130,309]	-8	hSpCas9	negative selection	8436845
65251071	65251094	2	-	27260156	RDES	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.3301207788406644	[243]	[86,116,144,97]	-9	hSpCas9	negative selection	8501127
65253843	65253866	2	+	27260156	PC3	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.6538459478103205	[218]	[54,109,394,123]	-9	hSpCas9	negative selection	8558094
65239843	65239866	2	+	27260156	PC3	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.02108804421540944	[705]	[425,575,1386,714]	0	hSpCas9	negative selection	8558095
65253772	65253795	2	+	27260156	PC3	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.19511898536300132	[235]	[110,245,245,257]	-4	hSpCas9	negative selection	8558096
65251071	65251094	2	-	27260156	PC3	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.3662110951632118	[243]	[186,186,190,161]	-7	hSpCas9	negative selection	8622378
65253843	65253866	2	+	27260156	PATU8988T	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.9131137635302158	[218]	[21,83,76,42]	-9	hSpCas9	negative selection	8679345
65239843	65239866	2	+	27260156	PATU8988T	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.44486427043570437	[705]	[391,644,532,442]	-6	hSpCas9	negative selection	8679346
65253772	65253795	2	+	27260156	PATU8988T	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.6496493577702473	[235]	[166,173,144,93]	-7	hSpCas9	negative selection	8679347
65251071	65251094	2	-	27260156	PATU8988T	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-1.9186534586166974	[243]	[41,20,126,53]	-9	hSpCas9	negative selection	8743629
65253843	65253866	2	+	27260156	T47D	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.6871457274806283	[218]	[100,114,173,249]	-8	hSpCas9	negative selection	8800596
65239843	65239866	2	+	27260156	T47D	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.09253110242562979	[705]	[785,750,676,877]	-2	hSpCas9	negative selection	8800597
65253772	65253795	2	+	27260156	T47D	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.025959267218015336	[235]	[271,200,299,313]	0	hSpCas9	negative selection	8800598
65251071	65251094	2	-	27260156	T47D	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.7828280780527019	[243]	[146,167,164,180]	-9	hSpCas9	negative selection	8864880
65253843	65253866	2	+	27260156	SU8686	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.5385040757396518	[218]	[157,104,188,150]	-7	hSpCas9	negative selection	8921847
65239843	65239866	2	+	27260156	SU8686	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-1.0832652795764734	[705]	[364,295,267,399]	-8	hSpCas9	negative selection	8921848
65253772	65253795	2	+	27260156	SU8686	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-1.5171278655808567	[235]	[98,68,87,67]	-9	hSpCas9	negative selection	8921849
65251071	65251094	2	-	27260156	SU8686	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-2.027819875964795	[243]	[44,106,26,50]	-9	hSpCas9	negative selection	8986131
65253843	65253866	2	+	27260156	SKES1	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.8286582050607614	[218]	[121,113,167,88]	-9	hSpCas9	negative selection	9043098
65239843	65239866	2	+	27260156	SKES1	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.1701249598492353	[705]	[612,801,462,638]	-4	hSpCas9	negative selection	9043099
65253772	65253795	2	+	27260156	SKES1	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.2004063525322628	[235]	[250,235,152,189]	-4	hSpCas9	negative selection	9043100
65251071	65251094	2	-	27260156	SKES1	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.5956751418438977	[243]	[120,139,130,233]	-8	hSpCas9	negative selection	9107382
65253843	65253866	2	+	27260156	TOV112D	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-1.1913716403140098	[218]	[121,112,117,38]	-9	hSpCas9	negative selection	9164349
65239843	65239866	2	+	27260156	TOV112D	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.43460017345519336	[705]	[683,706,249,509]	-7	hSpCas9	negative selection	9164350
65253772	65253795	2	+	27260156	TOV112D	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.40816320300130293	[235]	[100,341,123,178]	-7	hSpCas9	negative selection	9164351
65251071	65251094	2	-	27260156	TOV112D	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.6357998027889664	[243]	[38,166,138,272]	-8	hSpCas9	negative selection	9228633
65253843	65253866	2	+	27260156	TC71	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.4162774072286137	[218]	[141,312,132,113]	-8	hSpCas9	negative selection	9285600
65239843	65239866	2	+	27260156	TC71	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.12274213018489416	[705]	[758,731,635,650]	-3	hSpCas9	negative selection	9285601
65253772	65253795	2	+	27260156	TC71	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	0.050834031781923805	[235]	[313,226,319,178]	1	hSpCas9	negative selection	9285602
65251071	65251094	2	-	27260156	TC71	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.8371935056221778	[243]	[117,148,135,185]	-9	hSpCas9	negative selection	9349884
65253843	65253866	2	+	27260156	TC32	viability	TATAACTAGATATCTTATCAAGG	ACTR2	ENSG00000138071	-0.5828772208238258	[218]	[71,145,230,111]	-8	hSpCas9	negative selection	9406851
65239843	65239866	2	+	27260156	TC32	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.30520145097583384	[705]	[385,379,826,660]	-5	hSpCas9	negative selection	9406852
65253772	65253795	2	+	27260156	TC32	viability	CACATTTGCCCAGTATATGAAGG	ACTR2	ENSG00000138071	-0.14716647680751094	[235]	[126,189,302,199]	-3	hSpCas9	negative selection	9406853
65251071	65251094	2	-	27260156	TC32	viability	CGTACAAAGTCAGAACTGCCTGG	ACTR2	ENSG00000138071	-0.7171488921719269	[243]	[113,97,190,176]	-8	hSpCas9	negative selection	9471135
65227936	65227959	2	+	28162770	P31FUJ	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-2.817764705135535	[53]	[8]	-9	hSpCas9	negative selection	10106512
65268614	65268637	2	-	28162770	P31FUJ	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-1.9478986186199942	[370]	[112]	-8	hSpCas9	negative selection	10106513
65227901	65227924	2	+	28162770	P31FUJ	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-1.1624128765229806	[39]	[20]	-7	hSpCas9	negative selection	10106514
65265101	65265124	2	-	28162770	P31FUJ	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-2.3080903317186157	[471]	[111]	-8	hSpCas9	negative selection	10106515
65261255	65261278	2	+	28162770	P31FUJ	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-1.5487687410630242	[482]	[193]	-7	hSpCas9	negative selection	10106516
65239843	65239866	2	+	28162770	P31FUJ	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.24785655013666788	[288]	[285]	-2	hSpCas9	negative selection	10106517
65261235	65261258	2	+	28162770	P31FUJ	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-1.554730299301741	[174]	[69]	-7	hSpCas9	negative selection	10106518
65265091	65265114	2	+	28162770	P31FUJ	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-4.332337877965293	[119]	[6]	-9	hSpCas9	negative selection	10106519
65268588	65268611	2	-	28162770	P31FUJ	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	0.3338980899140493	[211]	[313]	3	hSpCas9	negative selection	10106520
65268575	65268598	2	-	28162770	P31FUJ	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.606347574774759	[376]	[290]	-5	hSpCas9	negative selection	10106521
65227936	65227959	2	+	28162770	TF1	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10275878
65268614	65268637	2	-	28162770	TF1	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10275879
65227901	65227924	2	+	28162770	TF1	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10275880
65265101	65265124	2	-	28162770	TF1	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10275881
65261255	65261278	2	+	28162770	TF1	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10275882
65239843	65239866	2	+	28162770	TF1	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10275883
65261235	65261258	2	+	28162770	TF1	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10275884
65265091	65265114	2	+	28162770	TF1	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10275885
65268588	65268611	2	-	28162770	TF1	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10275886
65268575	65268598	2	-	28162770	TF1	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10275887
65227936	65227959	2	+	28162770	SKM1	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-3.6293566200796095	[13]	[1]	-9	hSpCas9	negative selection	10445244
65268614	65268637	2	-	28162770	SKM1	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-2.448186861469675	[70]	[22]	-9	hSpCas9	negative selection	10445245
65227901	65227924	2	+	28162770	SKM1	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.9740047914670558	[9]	[8]	-6	hSpCas9	negative selection	10445246
65265101	65265124	2	-	28162770	SKM1	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-2.082961775617941	[138]	[57]	-8	hSpCas9	negative selection	10445247
65261255	65261278	2	+	28162770	SKM1	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-1.8764494820443818	[161]	[77]	-8	hSpCas9	negative selection	10445248
65239843	65239866	2	+	28162770	SKM1	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	0.07685157852109492	[95]	[178]	0	hSpCas9	negative selection	10445249
65261235	65261258	2	+	28162770	SKM1	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-1.0443941193584534	[41]	[35]	-6	hSpCas9	negative selection	10445250
65265091	65265114	2	+	28162770	SKM1	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-3.484966710744435	[18]	[2]	-9	hSpCas9	negative selection	10445251
65268588	65268611	2	-	28162770	SKM1	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.027320605999512027	[48]	[84]	0	hSpCas9	negative selection	10445252
65268575	65268598	2	-	28162770	SKM1	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.953246231300258	[91]	[83]	-6	hSpCas9	negative selection	10445253
65227936	65227959	2	+	28162770	SKM1	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-3.6293566200796095	[13]	[1]	-9	hSpCas9	negative selection	10614610
65268614	65268637	2	-	28162770	SKM1	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-2.448186861469675	[70]	[22]	-9	hSpCas9	negative selection	10614611
65227901	65227924	2	+	28162770	SKM1	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.9740047914670558	[9]	[8]	-6	hSpCas9	negative selection	10614612
65265101	65265124	2	-	28162770	SKM1	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-2.082961775617941	[138]	[57]	-8	hSpCas9	negative selection	10614613
65261255	65261278	2	+	28162770	SKM1	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-1.8764494820443818	[161]	[77]	-8	hSpCas9	negative selection	10614614
65239843	65239866	2	+	28162770	SKM1	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	0.07685157852109492	[95]	[178]	0	hSpCas9	negative selection	10614615
65261235	65261258	2	+	28162770	SKM1	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-1.0443941193584534	[41]	[35]	-6	hSpCas9	negative selection	10614616
65265091	65265114	2	+	28162770	SKM1	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-3.484966710744435	[18]	[2]	-9	hSpCas9	negative selection	10614617
65268588	65268611	2	-	28162770	SKM1	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.027320605999512027	[48]	[84]	0	hSpCas9	negative selection	10614618
65268575	65268598	2	-	28162770	SKM1	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.953246231300258	[91]	[83]	-6	hSpCas9	negative selection	10614619
65227936	65227959	2	+	28162770	PL21	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-3.929143402455647	[34]	[0]	-9	hSpCas9	negative selection	10783976
65268614	65268637	2	-	28162770	PL21	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-1.5971264899447002	[284]	[40]	-7	hSpCas9	negative selection	10783977
65227901	65227924	2	+	28162770	PL21	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	1.1070302100978386	[63]	[59]	8	hSpCas9	negative selection	10783978
65265101	65265124	2	-	28162770	PL21	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-3.756962427072966	[496]	[15]	-9	hSpCas9	negative selection	10783979
65261255	65261278	2	+	28162770	PL21	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-1.2950262158811903	[653]	[115]	-7	hSpCas9	negative selection	10783980
65239843	65239866	2	+	28162770	PL21	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	1.2143069464159137	[303]	[306]	8	hSpCas9	negative selection	10783981
65261235	65261258	2	+	28162770	PL21	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-0.6967668925465763	[107]	[28]	-5	hSpCas9	negative selection	10783982
65265091	65265114	2	+	28162770	PL21	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-1.2058527451865166	[52]	[9]	-7	hSpCas9	negative selection	10783983
65268588	65268611	2	-	28162770	PL21	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	2.0573994423732382	[137]	[249]	9	hSpCas9	negative selection	10783984
65268575	65268598	2	-	28162770	PL21	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.5088116035072895	[254]	[77]	-4	hSpCas9	negative selection	10783985
65227936	65227959	2	+	28162770	P31FUJ	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-2.817764705135535	[53]	[8]	-9	hSpCas9	negative selection	10953342
65268614	65268637	2	-	28162770	P31FUJ	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-1.9478986186199942	[370]	[112]	-8	hSpCas9	negative selection	10953343
65227901	65227924	2	+	28162770	P31FUJ	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-1.1624128765229806	[39]	[20]	-7	hSpCas9	negative selection	10953344
65265101	65265124	2	-	28162770	P31FUJ	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-2.3080903317186157	[471]	[111]	-8	hSpCas9	negative selection	10953345
65261255	65261278	2	+	28162770	P31FUJ	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-1.5487687410630242	[482]	[193]	-7	hSpCas9	negative selection	10953346
65239843	65239866	2	+	28162770	P31FUJ	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.24785655013666788	[288]	[285]	-2	hSpCas9	negative selection	10953347
65261235	65261258	2	+	28162770	P31FUJ	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-1.554730299301741	[174]	[69]	-7	hSpCas9	negative selection	10953348
65265091	65265114	2	+	28162770	P31FUJ	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-4.332337877965293	[119]	[6]	-9	hSpCas9	negative selection	10953349
65268588	65268611	2	-	28162770	P31FUJ	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	0.3338980899140493	[211]	[313]	3	hSpCas9	negative selection	10953350
65268575	65268598	2	-	28162770	P31FUJ	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.606347574774759	[376]	[290]	-5	hSpCas9	negative selection	10953351
65227936	65227959	2	+	28162770	OCIAML5	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-3.6594214929216013	[20]	[2]	-9	hSpCas9	negative selection	11122708
65268614	65268637	2	-	28162770	OCIAML5	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-0.7121363097195221	[107]	[118]	-5	hSpCas9	negative selection	11122709
65227901	65227924	2	+	28162770	OCIAML5	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-1.1321744900567323	[33]	[27]	-6	hSpCas9	negative selection	11122710
65265101	65265124	2	-	28162770	OCIAML5	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-2.182845583333625	[326]	[129]	-8	hSpCas9	negative selection	11122711
65261255	65261278	2	+	28162770	OCIAML5	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-1.6618441551884569	[297]	[169]	-7	hSpCas9	negative selection	11122712
65239843	65239866	2	+	28162770	OCIAML5	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	0.2719221464114563	[155]	[339]	2	hSpCas9	negative selection	11122713
65261235	65261258	2	+	28162770	OCIAML5	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-2.5968095156219224	[123]	[36]	-8	hSpCas9	negative selection	11122714
65265091	65265114	2	+	28162770	OCIAML5	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	0.6664005180702524	[36]	[105]	6	hSpCas9	negative selection	11122715
65268588	65268611	2	-	28162770	OCIAML5	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	0.5081896426824649	[103]	[266]	4	hSpCas9	negative selection	11122716
65268575	65268598	2	-	28162770	OCIAML5	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-1.0390295026628469	[180]	[158]	-6	hSpCas9	negative selection	11122717
65227936	65227959	2	+	28162770	EOL1	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-2.342238769124367	[76]	[7]	-8	hSpCas9	negative selection	11292074
65268614	65268637	2	-	28162770	EOL1	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-1.342238769124367	[307]	[63]	-7	hSpCas9	negative selection	11292075
65227901	65227924	2	+	28162770	EOL1	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.17498790198037995	[89]	[41]	-1	hSpCas9	negative selection	11292076
65265101	65265124	2	-	28162770	EOL1	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-1.4478920283942756	[900]	[173]	-7	hSpCas9	negative selection	11292077
65261255	65261278	2	+	28162770	EOL1	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-1.3610132032798674	[1135]	[232]	-7	hSpCas9	negative selection	11292078
65239843	65239866	2	+	28162770	EOL1	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.4887292698438718	[545]	[204]	-4	hSpCas9	negative selection	11292079
65261235	65261258	2	+	28162770	EOL1	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-2.5804464244472065	[192]	[16]	-9	hSpCas9	negative selection	11292080
65265091	65265114	2	+	28162770	EOL1	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-4.119846347787918	[65]	[1]	-9	hSpCas9	negative selection	11292081
65268588	65268611	2	-	28162770	EOL1	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.8759207649018296	[208]	[59]	-6	hSpCas9	negative selection	11292082
65268575	65268598	2	-	28162770	EOL1	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.7737142932651875	[330]	[101]	-5	hSpCas9	negative selection	11292083
65227936	65227959	2	+	28162770	MOLM13	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-4.889662623073505	[81]	[1]	-9	hSpCas9	negative selection	11461440
65268614	65268637	2	-	28162770	MOLM13	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-1.2375859264938116	[286]	[87]	-6	hSpCas9	negative selection	11461441
65227901	65227924	2	+	28162770	MOLM13	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.9106222417091512	[77]	[29]	-5	hSpCas9	negative selection	11461442
65265101	65265124	2	-	28162770	MOLM13	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-5.456923122061202	[728]	[11]	-9	hSpCas9	negative selection	11461443
65261255	65261278	2	+	28162770	MOLM13	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-2.5801005613902546	[702]	[84]	-8	hSpCas9	negative selection	11461444
65239843	65239866	2	+	28162770	MOLM13	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.39420850510745725	[328]	[180]	-2	hSpCas9	negative selection	11461445
65261235	65261258	2	+	28162770	MOLM13	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-1.8618160639345027	[185]	[36]	-7	hSpCas9	negative selection	11461446
65265091	65265114	2	+	28162770	MOLM13	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-4.2139346584291655	[76]	[2]	-9	hSpCas9	negative selection	11461447
65268588	65268611	2	-	28162770	MOLM13	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.7471235094262714	[129]	[55]	-4	hSpCas9	negative selection	11461448
65268575	65268598	2	-	28162770	MOLM13	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-2.184684025331255	[414]	[65]	-7	hSpCas9	negative selection	11461449
65227936	65227959	2	+	28162770	HEL	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-1.3381523450519388	[74]	[18]	-6	hSpCas9	negative selection	11630806
65268614	65268637	2	-	28162770	HEL	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-0.8366134807602005	[236]	[84]	-5	hSpCas9	negative selection	11630807
65227901	65227924	2	+	28162770	HEL	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.4567968415505572	[89]	[41]	-3	hSpCas9	negative selection	11630808
65265101	65265124	2	-	28162770	HEL	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-1.3661942927696507	[647]	[160]	-7	hSpCas9	negative selection	11630809
65261255	65261278	2	+	28162770	HEL	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-0.8358257452117254	[796]	[285]	-5	hSpCas9	negative selection	11630810
65239843	65239866	2	+	28162770	HEL	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.32572559456653616	[361]	[184]	-2	hSpCas9	negative selection	11630811
65261235	65261258	2	+	28162770	HEL	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-1.299158213436075	[145]	[37]	-6	hSpCas9	negative selection	11630812
65265091	65265114	2	+	28162770	HEL	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-1.6448377580962283	[82]	[16]	-7	hSpCas9	negative selection	11630813
65268588	65268611	2	-	28162770	HEL	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	0.29157351588789804	[161]	[126]	2	hSpCas9	negative selection	11630814
65268575	65268598	2	-	28162770	HEL	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-1.5067220668822399	[314]	[70]	-7	hSpCas9	negative selection	11630815
65227936	65227959	2	+	28162770	MV411	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-2.7780975413243625	[56]	[6]	-9	hSpCas9	negative selection	11800172
65268614	65268637	2	-	28162770	MV411	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-0.4655899887266757	[258]	[157]	-3	hSpCas9	negative selection	11800173
65227901	65227924	2	+	28162770	MV411	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.4895280433834308	[54]	[32]	-4	hSpCas9	negative selection	11800174
65265101	65265124	2	-	28162770	MV411	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-2.6138561783856327	[544]	[74]	-9	hSpCas9	negative selection	11800175
65261255	65261278	2	+	28162770	MV411	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-0.9224874506595371	[575]	[255]	-6	hSpCas9	negative selection	11800176
65239843	65239866	2	+	28162770	MV411	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.9870277028542477	[359]	[152]	-6	hSpCas9	negative selection	11800177
65261235	65261258	2	+	28162770	MV411	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-0.6426848314448512	[138]	[74]	-4	hSpCas9	negative selection	11800178
65265091	65265114	2	+	28162770	MV411	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-0.39789756791786246	[60]	[38]	-3	hSpCas9	negative selection	11800179
65268588	65268611	2	-	28162770	MV411	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.2742600564803643	[144]	[100]	-2	hSpCas9	negative selection	11800180
65268575	65268598	2	-	28162770	MV411	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	0.22277549654850615	[294]	[289]	2	hSpCas9	negative selection	11800181
65227936	65227959	2	+	28162770	MONOMAC1	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-2.389681925001949	[31]	[6]	-9	hSpCas9	negative selection	11969538
65268614	65268637	2	-	28162770	MONOMAC1	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-2.1869831823956307	[142]	[35]	-9	hSpCas9	negative selection	11969539
65227901	65227924	2	+	28162770	MONOMAC1	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-1.0715059649756948	[32]	[17]	-7	hSpCas9	negative selection	11969540
65265101	65265124	2	-	28162770	MONOMAC1	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-2.2199736583367127	[316]	[77]	-9	hSpCas9	negative selection	11969541
65261255	65261278	2	+	28162770	MONOMAC1	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-1.2989992580050078	[424]	[197]	-7	hSpCas9	negative selection	11969542
65239843	65239866	2	+	28162770	MONOMAC1	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.11099701599286232	[178]	[189]	-1	hSpCas9	negative selection	11969543
65261235	65261258	2	+	28162770	MONOMAC1	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-1.1774080403106213	[72]	[36]	-7	hSpCas9	negative selection	11969544
65265091	65265114	2	+	28162770	MONOMAC1	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-1.6564684656968511	[43]	[15]	-8	hSpCas9	negative selection	11969545
65268588	65268611	2	-	28162770	MONOMAC1	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.10082153180025061	[86]	[92]	-1	hSpCas9	negative selection	11969546
65268575	65268598	2	-	28162770	MONOMAC1	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	0.12623266590761018	[214]	[268]	1	hSpCas9	negative selection	11969547
65227936	65227959	2	+	28162770	OCIAML2	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-0.06463746556632444	[9]	[52]	0	hSpCas9	negative selection	12138904
65268614	65268637	2	-	28162770	OCIAML2	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-0.9455387804984039	[40]	[117]	-6	hSpCas9	negative selection	12138905
65227901	65227924	2	+	28162770	OCIAML2	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.11073388015577823	[14]	[76]	-1	hSpCas9	negative selection	12138906
65265101	65265124	2	-	28162770	OCIAML2	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-1.4517707979908452	[75]	[153]	-7	hSpCas9	negative selection	12138907
65261255	65261278	2	+	28162770	OCIAML2	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-2.749165324616143	[130]	[107]	-9	hSpCas9	negative selection	12138908
65239843	65239866	2	+	28162770	OCIAML2	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	0.29730474708181076	[52]	[360]	3	hSpCas9	negative selection	12138909
65261235	65261258	2	+	28162770	OCIAML2	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-0.2227023117985758	[19]	[94]	-2	hSpCas9	negative selection	12138910
65265091	65265114	2	+	28162770	OCIAML2	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-0.3831669839918219	[7]	[33]	-3	hSpCas9	negative selection	12138911
65268588	65268611	2	-	28162770	OCIAML2	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.04320860150748501	[28]	[155]	0	hSpCas9	negative selection	12138912
65268575	65268598	2	-	28162770	OCIAML2	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.1219016710110836	[31]	[162]	-1	hSpCas9	negative selection	12138913
65227936	65227959	2	+	28162770	OCIAML3	viability	GGTGTGCGACAACGGCACCGGGG	ACTR2	ENSG00000138071	-1.9419309437444698	[13]	[10]	-8	hSpCas9	negative selection	12308270
65268614	65268637	2	-	28162770	OCIAML3	viability	CCGCTAGAACTGCACCACCCAGG	ACTR2	ENSG00000138071	-1.7375984939530134	[94]	[85]	-8	hSpCas9	negative selection	12308271
65227901	65227924	2	+	28162770	OCIAML3	viability	GGGCGGACGATGGACAGCCAGGG	ACTR2	ENSG00000138071	-0.9265829794110336	[16]	[26]	-6	hSpCas9	negative selection	12308272
65265101	65265124	2	-	28162770	OCIAML3	viability	AGTTCTCGTTCCAACCGTGATGG	ACTR2	ENSG00000138071	-1.7704342077084305	[138]	[122]	-8	hSpCas9	negative selection	12308273
65261255	65261278	2	+	28162770	OCIAML3	viability	TGGACGTATCATCAAAGTTGGGG	ACTR2	ENSG00000138071	-0.9289466007316808	[180]	[286]	-6	hSpCas9	negative selection	12308274
65239843	65239866	2	+	28162770	OCIAML3	viability	TCATTCCAGTTTGTGAAGTGTGG	ACTR2	ENSG00000138071	-0.7562790692230402	[93]	[167]	-5	hSpCas9	negative selection	12308275
65261235	65261258	2	+	28162770	OCIAML3	viability	CTTGGTTTCTAGCTCCCAGATGG	ACTR2	ENSG00000138071	-0.33766788706437756	[35]	[85]	-3	hSpCas9	negative selection	12308276
65265091	65265114	2	+	28162770	OCIAML3	viability	TCCTGGCCTGCCATCACGGTTGG	ACTR2	ENSG00000138071	-2.237863830098888	[24]	[15]	-8	hSpCas9	negative selection	12308277
65268588	65268611	2	-	28162770	OCIAML3	viability	ACCATGTGCTTTCTGCGGGGTGG	ACTR2	ENSG00000138071	-0.6121549870344225	[39]	[78]	-5	hSpCas9	negative selection	12308278
65268575	65268598	2	-	28162770	OCIAML3	viability	TGCGGGGTGGGTCTTCAATGCGG	ACTR2	ENSG00000138071	-0.18372367101595388	[75]	[201]	-1	hSpCas9	negative selection	12308279