Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10096
• Symbol:ACTR3
• Description:actin related protein 3

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTR3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
113913206	113913229	2	-	26472758	Jiyoye	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	1.0331096632833359	[80]	[124]	6	hSpCas9	negative selection	2200
113940072	113940095	2	+	26472758	Jiyoye	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-0.10739779132388483	[9]	[6]	-1	hSpCas9	negative selection	2201
113927339	113927362	2	+	26472758	Jiyoye	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.9823914302568522	[130]	[49]	-6	hSpCas9	negative selection	2202
113940060	113940083	2	+	26472758	Jiyoye	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.13154093889244578	[390]	[322]	1	hSpCas9	negative selection	2203
113890288	113890311	2	+	26472758	Jiyoye	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-0.4001795405517306	[202]	[115]	-3	hSpCas9	negative selection	2204
113951800	113951823	2	+	26472758	Jiyoye	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.2993249319332816	[655]	[401]	-2	hSpCas9	negative selection	2205
113951813	113951836	2	+	26472758	Jiyoye	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.02398178313624739	[119]	[88]	0	hSpCas9	negative selection	2206
113890269	113890292	2	+	26472758	Jiyoye	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.3948852408822177	[135]	[38]	-7	hSpCas9	negative selection	2207
113890302	113890325	2	+	26472758	Jiyoye	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-0.28248449788197605	[49]	[30]	-2	hSpCas9	negative selection	2208
113934336	113934359	2	+	26472758	Jiyoye	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	0.9217485543356316	[118]	[169]	6	hSpCas9	negative selection	2209
113913206	113913229	2	-	26472758	KBM7	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-0.9514257114507568	[485,371]	[76,126]	-6	hSpCas9	negative selection	193318
113940072	113940095	2	+	26472758	KBM7	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	0.2947075376319126	[80,48]	[22,48]	3	hSpCas9	negative selection	193319
113927339	113927362	2	+	26472758	KBM7	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.3823392792254531	[351,229]	[79,123]	-4	hSpCas9	negative selection	193320
113940060	113940083	2	+	26472758	KBM7	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.15054371519478305	[1330,1129]	[602,672]	1	hSpCas9	negative selection	193321
113890288	113890311	2	+	26472758	KBM7	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.4364757741234961	[765,551]	[119,106]	-7	hSpCas9	negative selection	193322
113951800	113951823	2	+	26472758	KBM7	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.2846702655604352	[2487,1458]	[968,544]	-3	hSpCas9	negative selection	193323
113951813	113951836	2	+	26472758	KBM7	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.3661328686379456	[982,813]	[274,371]	-3	hSpCas9	negative selection	193324
113890269	113890292	2	+	26472758	KBM7	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.860821840878308	[400,474]	[76,39]	-8	hSpCas9	negative selection	193325
113890302	113890325	2	+	26472758	KBM7	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-2.126864446574866	[475,438]	[24,70]	-8	hSpCas9	negative selection	193326
113934336	113934359	2	+	26472758	KBM7	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.6333121023919779	[931,818]	[237,288]	-5	hSpCas9	negative selection	193327
113913206	113913229	2	-	26472758	Raji	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	0.893258730020752	[173]	[74]	7	hSpCas9	negative selection	384436
113940072	113940095	2	+	26472758	Raji	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-1.2986088243022373	[52]	[4]	-7	hSpCas9	negative selection	384437
113927339	113927362	2	+	26472758	Raji	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.20073875998873247	[103]	[20]	-2	hSpCas9	negative selection	384438
113940060	113940083	2	+	26472758	Raji	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.07403976579052496	[568]	[138]	0	hSpCas9	negative selection	384439
113890288	113890311	2	+	26472758	Raji	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.090324622582251	[366]	[39]	-7	hSpCas9	negative selection	384440
113951800	113951823	2	+	26472758	Raji	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.13583258349972205	[1069]	[225]	-1	hSpCas9	negative selection	384441
113951813	113951836	2	+	26472758	Raji	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.8186158831826236	[379]	[49]	-6	hSpCas9	negative selection	384442
113890269	113890292	2	+	26472758	Raji	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.1046669417413897	[277]	[29]	-7	hSpCas9	negative selection	384443
113890302	113890325	2	+	26472758	Raji	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-3.1020698302553504	[221]	[5]	-9	hSpCas9	negative selection	384444
113934336	113934359	2	+	26472758	Raji	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.4570566414742115	[348]	[58]	-4	hSpCas9	negative selection	384445
113913206	113913229	2	-	26472758	K562	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-0.6442979387998082	[423]	[228]	-4	hSpCas9	negative selection	575554
113940072	113940095	2	+	26472758	K562	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	0.3617756783046058	[117]	[127]	3	hSpCas9	negative selection	575555
113927339	113927362	2	+	26472758	K562	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.7160529081469156	[143]	[73]	-4	hSpCas9	negative selection	575556
113940060	113940083	2	+	26472758	K562	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.25100638770120653	[873]	[877]	2	hSpCas9	negative selection	575557
113890288	113890311	2	+	26472758	K562	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.5286958699727247	[686]	[200]	-6	hSpCas9	negative selection	575558
113951800	113951823	2	+	26472758	K562	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	0.5863215223150755	[1577]	[1999]	5	hSpCas9	negative selection	575559
113951813	113951836	2	+	26472758	K562	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	0.33177769196524287	[816]	[867]	2	hSpCas9	negative selection	575560
113890269	113890292	2	+	26472758	K562	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.0223678130284544	[384]	[159]	-5	hSpCas9	negative selection	575561
113890302	113890325	2	+	26472758	K562	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	0.18603581753161041	[352]	[338]	1	hSpCas9	negative selection	575562
113934336	113934359	2	+	26472758	K562	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-1.0466719632983226	[809]	[330]	-5	hSpCas9	negative selection	575563
113927339	113927362	2	+	26627737	DLD1	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.5380366088536815	[232]	[125,5,20]	-5	hSpCas9	negative selection	808363
113927339	113927362	2	+	26627737	GBM cells	viability after 5 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.44212304294938154	[189]	[65,83]	-6	hSpCas9	negative selection	890678
113927339	113927362	2	+	26627737	GBM cells	viability after 13 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.2013314953463712	[189]	[51,38]	-8	hSpCas9	negative selection	972993
113927339	113927362	2	+	26627737	GBM cells	viability after 21 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-3.3064940573911894	[189]	[11,8]	-9	hSpCas9	negative selection	1055308
113927339	113927362	2	+	26627737	RPE1	viability after 9 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.329183881330052	[566]	[50,95]	-7	hSpCas9	negative selection	1137623
113927339	113927362	2	+	26627737	RPE1	viability after 12 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.9137901924948127	[566]	[75,85]	-6	hSpCas9	negative selection	1219938
113927339	113927362	2	+	26627737	RPE1	viability after 15 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.0681535446512722	[566]	[132,21]	-6	hSpCas9	negative selection	1302253
113927339	113927362	2	+	26627737	RPE1	viability after 18 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.2866742893318839	[566]	[39,86]	-7	hSpCas9	negative selection	1384568
113927339	113927362	2	+	26627737	HeLa	viability after 8 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.3942105264440583	[341]	[60,224,46]	-4	hSpCas9	negative selection	1466883
113927339	113927362	2	+	26627737	HeLa	viability after 12 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-2.6349146918879183	[341]	[35,9,23]	-9	hSpCas9	negative selection	1549198
113927339	113927362	2	+	26627737	HeLa	viability after 15 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-2.460528472459903	[341]	[31,3,40]	-9	hSpCas9	negative selection	1631513
113927339	113927362	2	+	26627737	HeLa	viability after 18 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-2.423495664681086	[341]	[22,2,40]	-9	hSpCas9	negative selection	1713828
113927339	113927362	2	+	26627737	HCT116	viability after 6 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	0.05135995612188113	[530]	[3,131]	0	hSpCas9	negative selection	1796143
113927339	113927362	2	+	26627737	HCT116	viability after 8 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.0809862313685021	[418]	[147,61,117]	-8	hSpCas9	negative selection	1878458
113927339	113927362	2	+	26627737	HCT116	viability after 9 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	0.8745896019867793	[530]	[493,74]	6	hSpCas9	negative selection	1960773
113927339	113927362	2	+	26627737	HCT116	viability after 12 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.7626902036158212	[418]	[127,108,151]	-7	hSpCas9	negative selection	2043088
113927339	113927362	2	+	26627737	HCT116	viability after 15 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.550710897348464	[418]	[55,85,100]	-8	hSpCas9	negative selection	2125403
113927339	113927362	2	+	26627737	HCT116	viability after 18 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.6385640946747726	[418]	[44,150,195]	-5	hSpCas9	negative selection	2207718
113916922	113916945	2	+	24336569	HL60	viability	GCTCAAAGGAGGGTGATGAAAGG	ACTR3	ENSG00000115091	0.16349760598294716	[896]	[2125]	1	hSpCas9	negative selection	2246483
113927339	113927362	2	+	24336569	HL60	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.216486431690053	[609]	[1110]	-2	hSpCas9	negative selection	2246484
113927353	113927376	2	-	24336569	HL60	viability	AATCTTCAACTATACCATGGCGG	ACTR3	ENSG00000115091	-0.07527669282792532	[697]	[1401]	0	hSpCas9	negative selection	2246485
113927365	113927388	2	+	24336569	HL60	viability	AGTTGAAGATTGGGACTTAATGG	ACTR3	ENSG00000115091	0.5167748285179339	[648]	[1964]	4	hSpCas9	negative selection	2246486
113927370	113927393	2	+	24336569	HL60	viability	AAGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	0.10394940808242392	[524]	[1193]	1	hSpCas9	negative selection	2246487
113927377	113927400	2	+	24336569	HL60	viability	GGACTTAATGGAAAGGTTTATGG	ACTR3	ENSG00000115091	1.2058178514515747	[58]	[287]	8	hSpCas9	negative selection	2246488
113931355	113931378	2	+	24336569	HL60	viability	TTTGAGTCCTTCAATGTTCCAGG	ACTR3	ENSG00000115091	-0.165997610840564	[491]	[927]	-1	hSpCas9	negative selection	2246489
113931362	113931385	2	-	24336569	HL60	viability	GTACAAGCCTGGAACATTGAAGG	ACTR3	ENSG00000115091	-0.36269255971554687	[781]	[1286]	-3	hSpCas9	negative selection	2246490
113934307	113934330	2	+	24336569	HL60	viability	CCTCAAGACAAGTAGGAGAACGG	ACTR3	ENSG00000115091	-0.23780612979828375	[369]	[663]	-2	hSpCas9	negative selection	2246491
113934318	113934341	2	+	24336569	HL60	viability	GTAGGAGAACGGACGTTGACCGG	ACTR3	ENSG00000115091	-0.4880666599673804	[1477]	[2229]	-4	hSpCas9	negative selection	2246492
113916922	113916945	2	+	24336569	KBM7	viability	GCTCAAAGGAGGGTGATGAAAGG	ACTR3	ENSG00000115091	0.030078656322801822	[664]	[1851]	0	hSpCas9	negative selection	2313660
113927339	113927362	2	+	24336569	KBM7	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.344325234751858	[464]	[998]	-3	hSpCas9	negative selection	2313661
113927353	113927376	2	-	24336569	KBM7	viability	AATCTTCAACTATACCATGGCGG	ACTR3	ENSG00000115091	-1.5937498446917777	[767]	[693]	-8	hSpCas9	negative selection	2313662
113927365	113927388	2	+	24336569	KBM7	viability	AGTTGAAGATTGGGACTTAATGG	ACTR3	ENSG00000115091	0.5990097823239013	[616]	[2548]	5	hSpCas9	negative selection	2313663
113927370	113927393	2	+	24336569	KBM7	viability	AAGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-0.39278672370850326	[309]	[643]	-3	hSpCas9	negative selection	2313664
113927377	113927400	2	+	24336569	KBM7	viability	GGACTTAATGGAAAGGTTTATGG	ACTR3	ENSG00000115091	0.1573379105479187	[358]	[1091]	1	hSpCas9	negative selection	2313665
113931355	113931378	2	+	24336569	KBM7	viability	TTTGAGTCCTTCAATGTTCCAGG	ACTR3	ENSG00000115091	0.3926403594143482	[433]	[1553]	3	hSpCas9	negative selection	2313666
113931362	113931385	2	-	24336569	KBM7	viability	GTACAAGCCTGGAACATTGAAGG	ACTR3	ENSG00000115091	-2.2990035153000035	[589]	[326]	-8	hSpCas9	negative selection	2313667
113934307	113934330	2	+	24336569	KBM7	viability	CCTCAAGACAAGTAGGAGAACGG	ACTR3	ENSG00000115091	-0.5481739880043723	[437]	[816]	-4	hSpCas9	negative selection	2313668
113934318	113934341	2	+	24336569	KBM7	viability	GTAGGAGAACGGACGTTGACCGG	ACTR3	ENSG00000115091	-0.7651051475346803	[1267]	[2034]	-5	hSpCas9	negative selection	2313669
113948364	113948387	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTCTTGAACTCCTGGGCTCGAG	ACTR3	ENSG00000115091	4.2770735618878515	[141,50]	[775,15]	9	dCas9-VP64	positive selection	2397412
113890446	113890469	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCGCCGGCCAGCGAGGGGTGGGG	ACTR3	ENSG00000115091	0.8987279177050302	[0,2]	[0,0]	3	dCas9-VP64	positive selection	2419335
113890421	113890444	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTAGGACTGACAGCCGGCGGCGG	ACTR3	ENSG00000115091	0.12154287833408262	[33,13]	[3,5]	0	dCas9-VP64	positive selection	2419336
113890468	113890491	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCCGCAGCCAGGGCCTCGCGGG	ACTR3	ENSG00000115091	-0.8354594925817873	[65,13]	[6,1]	-5	dCas9-VP64	positive selection	2419337
113936057	113936080	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAAGCAGTCTGCCCACCTTGG	ACTR3	ENSG00000115091	0.20576949065447114	[17,35]	[6,5]	1	dCas9-VP64	positive selection	2476391
113948364	113948387	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTCTTGAACTCCTGGGCTCGAG	ACTR3	ENSG00000115091	0.8672449668792414	[148,204]	[104,104]	6	dCas9-VP64	positive selection	2492667
113890446	113890469	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCGCCGGCCAGCGAGGGGTGGGG	ACTR3	ENSG00000115091	-0.061872751601341314	[43,4]	[10,3]	0	dCas9-VP64	positive selection	2514590
113890421	113890444	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTAGGACTGACAGCCGGCGGCGG	ACTR3	ENSG00000115091	0.1986396016839267	[20,15]	[8,3]	1	dCas9-VP64	positive selection	2514591
113890468	113890491	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCCGCAGCCAGGGCCTCGCGGG	ACTR3	ENSG00000115091	-0.7881883543797334	[64,152]	[14,24]	-7	dCas9-VP64	positive selection	2514592
113936057	113936080	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAAGCAGTCTGCCCACCTTGG	ACTR3	ENSG00000115091	0.6530020702020014	[53,174]	[34,79]	5	dCas9-VP64	positive selection	2571646
113934337	113934360	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	0.07661759659697043	[2,2]	[4,0]	1	hSpCas9	positive selection	2968754
113916950	113916973	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGACCTAGACTTCTTCATTGG	ACTR3	ENSG00000115091	0.12128218263373414	[5,5]	[5,4]	2	hSpCas9	positive selection	2968755
113934319	113934342	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGGAGAACGGACGTTGACCGG	ACTR3	ENSG00000115091	0.842326437909992	[3,3]	[4,7]	9	hSpCas9	positive selection	2968756
113939946	113939969	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCCCCTCTCTAGGCTGAAGGG	ACTR3	ENSG00000115091	0.16439786830827885	[5,5]	[5,4]	3	hSpCas9	positive selection	2968757
113934337	113934360	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	0.624290758606434	[2,2]	[3,2]	8	hSpCas9	positive selection	3036612
113916950	113916973	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGACCTAGACTTCTTCATTGG	ACTR3	ENSG00000115091	0.6388334533025234	[5,5]	[6,6]	9	hSpCas9	positive selection	3036613
113934319	113934342	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGGAGAACGGACGTTGACCGG	ACTR3	ENSG00000115091	0.4375957692942742	[3,3]	[4,2]	7	hSpCas9	positive selection	3036614
113939946	113939969	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCCCCTCTCTAGGCTGAAGGG	ACTR3	ENSG00000115091	0.43692018134992855	[5,5]	[5,4]	7	hSpCas9	positive selection	3036615
113951714	113951737		+	24336571	A375	resistance to PLX after 7 days	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.0650354242598375	[13,15]	[15,15]	2	hSpCas9	positive selection	3160069
113951560	113951583		-	24336571	A375	resistance to PLX after 7 days	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	0.49668260712788337	[1,1]	[2,2]	9	hSpCas9	positive selection	3160079
113951714	113951737		+	24336571	A375	resistance to PLX after 14 days	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.050904911554011875	[10,15]	[4,6]	0	hSpCas9	positive selection	3217862
113951560	113951583		-	24336571	A375	resistance to PLX after 14 days	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	0.9835124041552221	[1,1]	[1,1]	7	hSpCas9	positive selection	3217872
113951714	113951737		+	24336571	A375	viability after 7 days	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.14116873510907996	[17]	[13,15]	-2	hSpCas9	negative selection	3275655
113951560	113951583		-	24336571	A375	viability after 7 days	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.4189295693670192	[2]	[1,1]	-5	hSpCas9	negative selection	3275665
113951714	113951737		+	24336571	A375	viability after 14 days	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.25462288686242757	[17]	[10,15]	-3	hSpCas9	negative selection	3333448
113951560	113951583		-	24336571	A375	viability after 14 days	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.5348578505638604	[2]	[1,1]	-6	hSpCas9	negative selection	3333458
113951550	113951573	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	1.5694531267992848	[58,43]	[0,0]	6	hSpCas9	positive selection	3335443
113916908	113916931	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	0.6791570462250153	[102,87]	[0,0]	3	hSpCas9	positive selection	3335444
113951714	113951737	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.6404204007192676	[235,240]	[0,0]	-4	hSpCas9	positive selection	3335445
113916991	113917014	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	0.24609895602258094	[128,128]	[0,0]	1	hSpCas9	positive selection	3354693
113951745	113951768	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	0.07741712143090065	[144,144]	[0,0]	0	hSpCas9	positive selection	3354694
113951560	113951583	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	2.3504356158373163	[29,29]	[0,0]	8	hSpCas9	positive selection	3354695
113934336	113934359	2	+	26780180	HT29	viability (Avana library 4 designs)	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	3.10643329443617	[]	[]	8	hSpCas9	negative selection	3404702
113916949	113916972	2	+	26780180	HT29	viability (Avana library 4 designs)	GATGACCTAGACTTCTTCATTGG	ACTR3	ENSG00000115091	1.2966008541221	[]	[]	5	hSpCas9	negative selection	3404703
113934318	113934341	2	+	26780180	HT29	viability (Avana library 4 designs)	GTAGGAGAACGGACGTTGACCGG	ACTR3	ENSG00000115091	3.2383086723853	[]	[]	8	hSpCas9	negative selection	3404704
113939945	113939968	2	+	26780180	HT29	viability (Avana library 4 designs)	TTTCCCCTCTCTAGGCTGAAGGG	ACTR3	ENSG00000115091	-0.175913077513884	[]	[]	-3	hSpCas9	negative selection	3404705
113939945	113939968	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCCCCTCTCTAGGCTGAAGGG	ACTR3	ENSG00000115091	1.85881944338367	[]	[]	2	hSpCas9	negative selection	3476369
113934336	113934359	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-1.12029784058551	[]	[]	-1	hSpCas9	negative selection	3476370
113934318	113934341	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGGAGAACGGACGTTGACCGG	ACTR3	ENSG00000115091	-0.166667381024942	[]	[]	0	hSpCas9	negative selection	3476371
113916949	113916972	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGACCTAGACTTCTTCATTGG	ACTR3	ENSG00000115091	1.4670614986033	[]	[]	2	hSpCas9	negative selection	3476372
113934300	113934323	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGGACCTCAAGACAAGTAGG	ACTR3	ENSG00000115091	-2.89027746979653	[]	[]	-3	hSpCas9	negative selection	3476373
113927353	113927376	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATCTTCAACTATACCATGGCGG	ACTR3	ENSG00000115091	-17.5650381419427	[]	[]	-9	hSpCas9	negative selection	3476374
113939945	113939968	2	+	26780180	A375	viability (Avana lentiGuide)	TTTCCCCTCTCTAGGCTGAAGGG	ACTR3	ENSG00000115091	-1.49916105395556	[]	[]	-2	hSpCas9	negative selection	3585028
113934336	113934359	2	+	26780180	A375	viability (Avana lentiGuide)	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	13.0614330974754	[]	[]	7	hSpCas9	negative selection	3585029
113934318	113934341	2	+	26780180	A375	viability (Avana lentiGuide)	GTAGGAGAACGGACGTTGACCGG	ACTR3	ENSG00000115091	6.57106368291918	[]	[]	5	hSpCas9	negative selection	3585030
113916949	113916972	2	+	26780180	A375	viability (Avana lentiGuide)	GATGACCTAGACTTCTTCATTGG	ACTR3	ENSG00000115091	5.0786559814381	[]	[]	4	hSpCas9	negative selection	3585031
113934300	113934323	2	+	26780180	A375	viability (Avana lentiGuide)	TCTTGGACCTCAAGACAAGTAGG	ACTR3	ENSG00000115091	9.99685165989611	[]	[]	7	hSpCas9	negative selection	3585032
113927353	113927376	2	-	26780180	A375	viability (Avana lentiGuide)	AATCTTCAACTATACCATGGCGG	ACTR3	ENSG00000115091	8.65963781555233	[]	[]	6	hSpCas9	negative selection	3585033
113939945	113939968	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCCCCTCTCTAGGCTGAAGGG	ACTR3	ENSG00000115091	0.04598241706937417	[6]	[7,6]	1	hSpCas9	positive selection	3693687
113934336	113934359	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	0.0010683646679538403	[5]	[5,4]	0	hSpCas9	positive selection	3693688
113934318	113934341	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGGAGAACGGACGTTGACCGG	ACTR3	ENSG00000115091	0.18626728363337486	[5]	[6,5]	5	hSpCas9	positive selection	3693689
113916949	113916972	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGACCTAGACTTCTTCATTGG	ACTR3	ENSG00000115091	0.12896195848840625	[6]	[7,7]	3	hSpCas9	positive selection	3693690
113934300	113934323	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGGACCTCAAGACAAGTAGG	ACTR3	ENSG00000115091	-0.0233661447505112	[5]	[4,4]	0	hSpCas9	positive selection	3693691
113927353	113927376	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCTTCAACTATACCATGGCGG	ACTR3	ENSG00000115091	-0.8137033636345676	[7]	[2,4]	-8	hSpCas9	positive selection	3693692
113939945	113939968	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCCCCTCTCTAGGCTGAAGGG	ACTR3	ENSG00000115091	0.28452017397993845	[7]	[7,7]	7	hSpCas9	positive selection	3802294
113934336	113934359	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.7172810748142918	[5]	[2,1]	-7	hSpCas9	positive selection	3802295
113934318	113934341	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGGAGAACGGACGTTGACCGG	ACTR3	ENSG00000115091	0.1290549091380446	[6]	[5,5]	3	hSpCas9	positive selection	3802296
113916949	113916972	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGACCTAGACTTCTTCATTGG	ACTR3	ENSG00000115091	0.18576440230885055	[7]	[7,7]	4	hSpCas9	positive selection	3802297
113934300	113934323	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGGACCTCAAGACAAGTAGG	ACTR3	ENSG00000115091	-0.10662662092745794	[5]	[3,4]	-1	hSpCas9	positive selection	3802298
113927353	113927376	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCTTCAACTATACCATGGCGG	ACTR3	ENSG00000115091	-0.21390243286321592	[6]	[4,4]	-3	hSpCas9	positive selection	3802299
113916908	113916931	2	+	26780180	A375	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	1.48725521076756	[]	[]	8	hSpCas9	negative selection	3910899
113951745	113951768	2	-	26780180	A375	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	2.53145042352613	[]	[]	9	hSpCas9	negative selection	3910900
113951714	113951737	2	+	26780180	A375	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	1.53921335867822	[]	[]	8	hSpCas9	negative selection	3910901
113916991	113917014	2	-	26780180	A375	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	0.954042809110626	[]	[]	4	hSpCas9	negative selection	3910902
113951560	113951583	2	-	26780180	A375	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	1.3401404577318	[]	[]	7	hSpCas9	negative selection	3910903
113951550	113951573	2	+	26780180	A375	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	1.64251039785186	[]	[]	8	hSpCas9	negative selection	3910904
113916908	113916931	2	+	26780180	HT29	viability (GeCKOv2 library)	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	1.66039352618164	[]	[]	8	hSpCas9	negative selection	4018865
113951745	113951768	2	-	26780180	HT29	viability (GeCKOv2 library)	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	2.24775614392838	[]	[]	9	hSpCas9	negative selection	4018866
113951714	113951737	2	+	26780180	HT29	viability (GeCKOv2 library)	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.912463266770616	[]	[]	4	hSpCas9	negative selection	4018867
113916991	113917014	2	-	26780180	HT29	viability (GeCKOv2 library)	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	1.34672036463404	[]	[]	6	hSpCas9	negative selection	4018868
113951560	113951583	2	-	26780180	HT29	viability (GeCKOv2 library)	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	1.83536821625197	[]	[]	8	hSpCas9	negative selection	4018869
113951550	113951573	2	+	26780180	HT29	viability (GeCKOv2 library)	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	2.16236215284113	[]	[]	9	hSpCas9	negative selection	4018870
113951714	113951737	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.0873140340676254	[3]	[1,2]	2	hSpCas9	positive selection	4188129
113951560	113951583	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.5752174400556844	[1]	[0,0]	-9	hSpCas9	positive selection	4188139
113951714	113951737	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.06917774837177364	[3]	[2,2,1,0]	0	hSpCas9	positive selection	4252151
113951560	113951583	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	1.024943406920589	[0]	[1,0,0,0]	7	hSpCas9	positive selection	4252161
113951550	113951573	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.6669505503384917	[2]	[1,0]	-9	hSpCas9	positive selection	4254362
113916908	113916931	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	0.002959462808745761	[3]	[4,1]	0	hSpCas9	positive selection	4254363
113951714	113951737	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.1930463265556483	[3]	[3,2]	4	hSpCas9	positive selection	4254364
113916991	113917014	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	0.14217038311978775	[2]	[2,1]	3	hSpCas9	positive selection	4318645
113951745	113951768	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.08821626358701776	[4]	[3,2]	-2	hSpCas9	positive selection	4318646
113951560	113951583	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.46927190197916135	[2]	[1,0]	-8	hSpCas9	positive selection	4318647
113927371	113927393	2	+	27760321	OCIAML3	viability	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-0.7244598151860697	[97,92]	[13,85]	-6	hSpCas9	negative selection	4375941
113931313	113931335	2	+	27760321	OCIAML3	viability	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-0.7572092050132646	[20,21]	[9,9]	-6	hSpCas9	negative selection	4375942
113934324	113934346	2	+	27760321	OCIAML3	viability	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-0.9102664951884312	[391,342]	[116,198]	-7	hSpCas9	negative selection	4375943
113934381	113934403	2	-	27760321	OCIAML3	viability	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-1.8067464042191776	[35,28]	[11,0]	-9	hSpCas9	negative selection	4375944
113939998	113940020	2	-	27760321	OCIAML3	viability	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-0.5624086976868905	[338,307]	[142,207]	-5	hSpCas9	negative selection	4375945
113927371	113927393	2	+	27760321	OCIAML2	viability	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-0.5276656107991724	[97,92]	[41,68]	-5	hSpCas9	negative selection	4459404
113931313	113931335	2	+	27760321	OCIAML2	viability	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	1.4059236293141981	[20,21]	[60,26]	9	hSpCas9	negative selection	4459405
113934324	113934346	2	+	27760321	OCIAML2	viability	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-0.20223980238275435	[391,342]	[259,254]	-3	hSpCas9	negative selection	4459406
113934381	113934403	2	-	27760321	OCIAML2	viability	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-3.510228719227153	[35,28]	[0,3]	-9	hSpCas9	negative selection	4459407
113939998	113940020	2	-	27760321	OCIAML2	viability	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	0.03257569041527614	[338,307]	[235,308]	0	hSpCas9	negative selection	4459408
113927371	113927393	2	+	27760321	MV411	viability	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-1.5468485571184618	[97,92]	[13,32]	-7	hSpCas9	negative selection	4542867
113931313	113931335	2	+	27760321	MV411	viability	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	0.11154524550978984	[20,21]	[24,0]	0	hSpCas9	negative selection	4542868
113934324	113934346	2	+	27760321	MV411	viability	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-0.18482678565034188	[391,342]	[74,419]	-1	hSpCas9	negative selection	4542869
113934381	113934403	2	-	27760321	MV411	viability	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-4.414651119052167	[35,28]	[0,0]	-9	hSpCas9	negative selection	4542870
113939998	113940020	2	-	27760321	MV411	viability	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-0.47247457182095565	[338,307]	[104,226]	-3	hSpCas9	negative selection	4542871
113927371	113927393	2	+	27760321	HL60	viability	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-0.2107545913176505	[97,92]	[66,67]	-2	hSpCas9	negative selection	4626330
113931313	113931335	2	+	27760321	HL60	viability	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-0.33155893296704697	[20,21]	[14,12]	-4	hSpCas9	negative selection	4626331
113934324	113934346	2	+	27760321	HL60	viability	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-2.3004531986419265	[391,342]	[70,49]	-9	hSpCas9	negative selection	4626332
113934381	113934403	2	-	27760321	HL60	viability	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-1.5155171745474387	[35,28]	[16,0]	-8	hSpCas9	negative selection	4626333
113939998	113940020	2	-	27760321	HL60	viability	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-0.5490050596976978	[338,307]	[163,197]	-5	hSpCas9	negative selection	4626334
113927371	113927393	2	+	27760321	HT1080	viability	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-5.04773388179869	[92,72]	[0,0]	-8	hSpCas9	negative selection	4709793
113931313	113931335	2	+	27760321	HT1080	viability	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-2.95669589080409	[21,16]	[0,0]	-7	hSpCas9	negative selection	4709794
113934324	113934346	2	+	27760321	HT1080	viability	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-6.9273118688825015	[342,267]	[0,0]	-9	hSpCas9	negative selection	4709795
113934381	113934403	2	-	27760321	HT1080	viability	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-3.3740579379166626	[28,22]	[0,0]	-7	hSpCas9	negative selection	4709796
113939998	113940020	2	-	27760321	HT1080	viability	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-2.7130751297587885	[307,240]	[30,0]	-7	hSpCas9	negative selection	4709797
113927371	113927393	2	+	27760321	HT29	viability after 7 days	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-0.5986843692629966	[92,72]	[28,122,53]	-7	hSpCas9	negative selection	4793256
113931313	113931335	2	+	27760321	HT29	viability after 7 days	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-1.5903466244399311	[21,16]	[6,16,0]	-9	hSpCas9	negative selection	4793257
113934324	113934346	2	+	27760321	HT29	viability after 7 days	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-0.33035530890884596	[342,267]	[434,324,197]	-5	hSpCas9	negative selection	4793258
113934381	113934403	2	-	27760321	HT29	viability after 7 days	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-0.9194956802914498	[28,22]	[30,7,15]	-8	hSpCas9	negative selection	4793259
113939998	113940020	2	-	27760321	HT29	viability after 7 days	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-0.5610876662768602	[307,240]	[344,132,253]	-7	hSpCas9	negative selection	4793260
113927371	113927393	2	+	27760321	HT29	viability after 25 days	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-0.3601048437114942	[92,72]	[31,77,118]	-4	hSpCas9	negative selection	4876719
113931313	113931335	2	+	27760321	HT29	viability after 25 days	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-0.2877006732778442	[21,16]	[0,51,0]	-3	hSpCas9	negative selection	4876720
113934324	113934346	2	+	27760321	HT29	viability after 25 days	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-1.8308400800767834	[342,267]	[87,90,117]	-8	hSpCas9	negative selection	4876721
113934381	113934403	2	-	27760321	HT29	viability after 25 days	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-4.893740202763187	[28,22]	[0,0,0]	-9	hSpCas9	negative selection	4876722
113939998	113940020	2	-	27760321	HT29	viability after 25 days	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-3.005505469514015	[307,240]	[42,33,39]	-8	hSpCas9	negative selection	4876723
113927371	113927393	2	+	27760321	HT29	viability after 22 days	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-1.1042187912679684	[92,72]	[18,32,82]	-7	hSpCas9	negative selection	4960182
113931313	113931335	2	+	27760321	HT29	viability after 22 days	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	0.753939000020416	[21,16]	[40,23,48]	8	hSpCas9	negative selection	4960183
113934324	113934346	2	+	27760321	HT29	viability after 22 days	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-1.258078509455677	[342,267]	[137,185,118]	-7	hSpCas9	negative selection	4960184
113934381	113934403	2	-	27760321	HT29	viability after 22 days	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-1.979773451784879	[28,22]	[0,20,0]	-8	hSpCas9	negative selection	4960185
113939998	113940020	2	-	27760321	HT29	viability after 22 days	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-1.490221975659216	[307,240]	[22,137,180]	-7	hSpCas9	negative selection	4960186
113927371	113927393	2	+	27760321	HT29	viability after 19 days	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-3.059065142781551	[92,72]	[6,22,3]	-8	hSpCas9	negative selection	5043645
113931313	113931335	2	+	27760321	HT29	viability after 19 days	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-4.093645772824764	[21,16]	[1,0,0]	-9	hSpCas9	negative selection	5043646
113934324	113934346	2	+	27760321	HT29	viability after 19 days	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	0.4844982472085378	[342,267]	[131,300,976]	5	hSpCas9	negative selection	5043647
113934381	113934403	2	-	27760321	HT29	viability after 19 days	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-2.8641292124462	[28,22]	[9,1,0]	-8	hSpCas9	negative selection	5043648
113939998	113940020	2	-	27760321	HT29	viability after 19 days	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-1.0365292910631467	[307,240]	[222,78,163]	-6	hSpCas9	negative selection	5043649
113927371	113927393	2	+	27760321	HT29	viability after 16 days	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-0.2643075122280907	[92,72]	[62,140,24]	-3	hSpCas9	negative selection	5127108
113931313	113931335	2	+	27760321	HT29	viability after 16 days	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-2.2076230862533173	[21,16]	[1,0,10]	-8	hSpCas9	negative selection	5127109
113934324	113934346	2	+	27760321	HT29	viability after 16 days	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-0.8971681623978265	[342,267]	[289,92,179]	-6	hSpCas9	negative selection	5127110
113934381	113934403	2	-	27760321	HT29	viability after 16 days	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-1.0197981289847298	[28,22]	[30,0,12]	-7	hSpCas9	negative selection	5127111
113939998	113940020	2	-	27760321	HT29	viability after 16 days	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-1.0364820068508631	[307,240]	[188,184,77]	-7	hSpCas9	negative selection	5127112
113927371	113927393	2	+	27760321	HT29	viability after 13 days	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-0.48398159871097723	[92,72]	[81,45,77]	-5	hSpCas9	negative selection	5210571
113931313	113931335	2	+	27760321	HT29	viability after 13 days	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-0.9418146423184854	[21,16]	[1,32,0]	-7	hSpCas9	negative selection	5210572
113934324	113934346	2	+	27760321	HT29	viability after 13 days	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-0.4253250656795618	[342,267]	[90,314,378]	-5	hSpCas9	negative selection	5210573
113934381	113934403	2	-	27760321	HT29	viability after 13 days	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-0.19177360141297228	[28,22]	[5,40,31]	-2	hSpCas9	negative selection	5210574
113939998	113940020	2	-	27760321	HT29	viability after 13 days	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-1.2593515391258556	[307,240]	[131,114,150]	-8	hSpCas9	negative selection	5210575
113927371	113927393	2	+	27760321	HT29	viability after 10 days	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-1.411893265365474	[92,72]	[66,48,1]	-8	hSpCas9	negative selection	5294034
113931313	113931335	2	+	27760321	HT29	viability after 10 days	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-0.9018658547203025	[21,16]	[36,0,0]	-7	hSpCas9	negative selection	5294035
113934324	113934346	2	+	27760321	HT29	viability after 10 days	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-0.3692986778195419	[342,267]	[236,443,210]	-5	hSpCas9	negative selection	5294036
113934381	113934403	2	-	27760321	HT29	viability after 10 days	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-0.3060958974145769	[28,22]	[44,0,31]	-4	hSpCas9	negative selection	5294037
113939998	113940020	2	-	27760321	HT29	viability after 10 days	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-1.140280348091527	[307,240]	[135,113,213]	-8	hSpCas9	negative selection	5294038
113927371	113927393	2	+	27760321	MOLM13	viability	AGATTGGGACTTAATGGAAAGG	ACTR3	ENSG00000115091	-5.753330182259502	[97,92]	[0,0]	-9	hSpCas9	negative selection	5377497
113931313	113931335	2	+	27760321	MOLM13	viability	TTGAATACTCCAGAAAACAGGG	ACTR3	ENSG00000115091	-3.60800191815835	[20,21]	[0,0]	-9	hSpCas9	negative selection	5377498
113934324	113934346	2	+	27760321	MOLM13	viability	GAACGGACGTTGACCGGTACGG	ACTR3	ENSG00000115091	-0.7859586007178567	[391,342]	[25,199]	-5	hSpCas9	negative selection	5377499
113934381	113934403	2	-	27760321	MOLM13	viability	TGTAAAATAGCCTTACCACAGG	ACTR3	ENSG00000115091	-4.188594306224572	[35,28]	[0,0]	-9	hSpCas9	negative selection	5377500
113939998	113940020	2	-	27760321	MOLM13	viability	TTATATCTCGTCCTGCGATTGG	ACTR3	ENSG00000115091	-2.232024621240944	[338,307]	[20,53]	-8	hSpCas9	negative selection	5377501
113890386	113890409	2	+	27661255	K562	viability	GGAGGAGGCCGGGAAATGAATGG	ACTR3	ENSG00000115091	-0.019338359092144985	[1124,1058]	[839,879]	0	dCas9-KRAB	negative selection	5460772
113890424	113890447	2	-	27661255	K562	viability	GGTCTAGGACTGACAGCCGGCGG	ACTR3	ENSG00000115091	-0.05867835166713131	[1429,1523]	[1259,1021]	-2	dCas9-KRAB	negative selection	5460773
113890493	113890516	2	-	27661255	K562	viability	GTCCCAGGAGGGAGAAACGAGGG	ACTR3	ENSG00000115091	-0.37131269193273087	[547,607]	[399,318]	-7	dCas9-KRAB	negative selection	5460774
113890548	113890571	2	-	27661255	K562	viability	GAGAAAGCCGCTGGGAGGGTTGG	ACTR3	ENSG00000115091	-0.2351033553685253	[1073,1019]	[822,615]	-6	dCas9-KRAB	negative selection	5460775
113951550	113951573	2	+	27260156	BXPC3	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.7075954919685314	[365]	[226,210,252,248]	-8	hSpCas9	negative selection	5526822
113916908	113916931	2	+	27260156	BXPC3	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.5495576885880632	[745]	[456,517,505,672]	-8	hSpCas9	negative selection	5526823
113951714	113951737	2	+	27260156	BXPC3	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.04078338414307703	[799]	[649,780,897,956]	-1	hSpCas9	negative selection	5526824
113916991	113917014	2	-	27260156	BXPC3	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.20345844383555667	[341]	[231,311,329,383]	-5	hSpCas9	negative selection	5591105
113951745	113951768	2	-	27260156	BXPC3	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.7644205447131969	[997]	[481,675,535,789]	-9	hSpCas9	negative selection	5591106
113951560	113951583	2	-	27260156	BXPC3	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.8831309992162066	[203]	[67,136,122,140]	-9	hSpCas9	negative selection	5591107
113951550	113951573	2	+	27260156	A673	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.31878368722557915	[365]	[371,294,378,366]	-7	hSpCas9	negative selection	5648073
113916908	113916931	2	+	27260156	A673	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.49098440316673	[745]	[758,574,566,664]	-8	hSpCas9	negative selection	5648074
113951714	113951737	2	+	27260156	A673	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.0544262618763498	[799]	[1191,723,799,1024]	-1	hSpCas9	negative selection	5648075
113916991	113917014	2	-	27260156	A673	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.48021278385338007	[341]	[305,306,316,244]	-8	hSpCas9	negative selection	5712356
113951745	113951768	2	-	27260156	A673	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.5415268665427591	[997]	[862,655,800,989]	-8	hSpCas9	negative selection	5712357
113951560	113951583	2	-	27260156	A673	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.7005789770353508	[203]	[179,141,94,191]	-9	hSpCas9	negative selection	5712358
113951550	113951573	2	+	27260156	A375	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.8188839077212331	[365]	[275,252,206,234]	-8	hSpCas9	negative selection	5769324
113916908	113916931	2	+	27260156	A375	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.6274460693927463	[745]	[668,474,660,450]	-7	hSpCas9	negative selection	5769325
113951714	113951737	2	+	27260156	A375	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.25953730996542	[799]	[716,927,868,641]	-4	hSpCas9	negative selection	5769326
113916991	113917014	2	-	27260156	A375	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.36342047396212573	[341]	[313,380,340,224]	-5	hSpCas9	negative selection	5833607
113951745	113951768	2	-	27260156	A375	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-1.200085599275256	[997]	[645,545,557,307]	-8	hSpCas9	negative selection	5833608
113951560	113951583	2	-	27260156	A375	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.4956269336718528	[203]	[99,69,101,65]	-9	hSpCas9	negative selection	5833609
113951550	113951573	2	+	27260156	COLO741	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.3286332612275158	[365]	[503,303,322]	-6	hSpCas9	negative selection	5890575
113916908	113916931	2	+	27260156	COLO741	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.05696154828426658	[745]	[855,930,951]	-1	hSpCas9	negative selection	5890576
113951714	113951737	2	+	27260156	COLO741	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.219280284698406	[799]	[1282,1395,916]	4	hSpCas9	negative selection	5890577
113916991	113917014	2	-	27260156	COLO741	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.5925713542988391	[341]	[362,294,221]	-8	hSpCas9	negative selection	5954858
113951745	113951768	2	-	27260156	COLO741	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.6915188087013054	[997]	[938,729,715]	-8	hSpCas9	negative selection	5954859
113951560	113951583	2	-	27260156	COLO741	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.5743604106849021	[203]	[138,182,197]	-8	hSpCas9	negative selection	5954860
113951550	113951573	2	+	27260156	CAL120	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.8450602631909083	[365]	[239,293,224]	-8	hSpCas9	negative selection	6011826
113916908	113916931	2	+	27260156	CAL120	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.878485944387426	[745]	[788,354,414]	-8	hSpCas9	negative selection	6011827
113951714	113951737	2	+	27260156	CAL120	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.17139658815025116	[799]	[1100,1540,724]	2	hSpCas9	negative selection	6011828
113916991	113917014	2	-	27260156	CAL120	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.11575038338845334	[341]	[444,403,337]	-2	hSpCas9	negative selection	6076109
113951745	113951768	2	-	27260156	CAL120	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-1.6194227695577146	[997]	[466,413,341]	-9	hSpCas9	negative selection	6076110
113951560	113951583	2	-	27260156	CAL120	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.4908241662235548	[203]	[85,133,50]	-9	hSpCas9	negative selection	6076111
113951550	113951573	2	+	27260156	CADOES1	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.2948551221199649	[365]	[244,269,214,383]	-5	hSpCas9	negative selection	6133077
113916908	113916931	2	+	27260156	CADOES1	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.26901944492577134	[745]	[651,556,414,682]	-5	hSpCas9	negative selection	6133078
113951714	113951737	2	+	27260156	CADOES1	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.518156550645799	[799]	[927,1001,1328,1000]	8	hSpCas9	negative selection	6133079
113916991	113917014	2	-	27260156	CADOES1	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	0.04837285497919003	[341]	[288,431,215,380]	0	hSpCas9	negative selection	6197360
113951745	113951768	2	-	27260156	CADOES1	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.2946027642572856	[997]	[870,633,725,796]	-5	hSpCas9	negative selection	6197361
113951560	113951583	2	-	27260156	CADOES1	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.2738231157105393	[203]	[96,154,138,239]	-5	hSpCas9	negative selection	6197362
113951550	113951573	2	+	27260156	EWS502	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.7833304772631817	[365]	[161,237,186,326]	-8	hSpCas9	negative selection	6254328
113916908	113916931	2	+	27260156	EWS502	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.22468504132218775	[745]	[546,727,748,693]	-4	hSpCas9	negative selection	6254329
113951714	113951737	2	+	27260156	EWS502	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.30203688643643667	[799]	[811,976,978,1466]	5	hSpCas9	negative selection	6254330
113916991	113917014	2	-	27260156	EWS502	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.03494660666279642	[341]	[263,376,362,423]	0	hSpCas9	negative selection	6318611
113951745	113951768	2	-	27260156	EWS502	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.38863697245744144	[997]	[674,814,742,1023]	-6	hSpCas9	negative selection	6318612
113951560	113951583	2	-	27260156	EWS502	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.121330326834301	[203]	[91,161,63,74]	-9	hSpCas9	negative selection	6318613
113951550	113951573	2	+	27260156	EW8	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.21501969083993988	[365]	[261,310,240,210]	-4	hSpCas9	negative selection	6375579
113916908	113916931	2	+	27260156	EW8	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.05866366814307755	[745]	[449,743,548,568]	-1	hSpCas9	negative selection	6375580
113951714	113951737	2	+	27260156	EW8	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.23442498087397778	[799]	[1156,896,505,576]	4	hSpCas9	negative selection	6375581
113916991	113917014	2	-	27260156	EW8	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.22667167956065404	[341]	[359,239,120,258]	-4	hSpCas9	negative selection	6439862
113951745	113951768	2	-	27260156	EW8	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.7598934791627947	[997]	[527,490,368,544]	-8	hSpCas9	negative selection	6439863
113951560	113951583	2	-	27260156	EW8	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.3810745049667621	[203]	[88,153,152,102]	-6	hSpCas9	negative selection	6439864
113951550	113951573	2	+	27260156	CORL105	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.5629050528820012	[365]	[281,274,314,291]	-7	hSpCas9	negative selection	6496830
113916908	113916931	2	+	27260156	CORL105	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.09453169238023995	[745]	[612,811,1119,766]	-2	hSpCas9	negative selection	6496831
113951714	113951737	2	+	27260156	CORL105	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.003119867963972456	[799]	[1014,811,1151,813]	0	hSpCas9	negative selection	6496832
113916991	113917014	2	-	27260156	CORL105	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.26431002914314294	[341]	[279,227,452,390]	-5	hSpCas9	negative selection	6561113
113951745	113951768	2	-	27260156	CORL105	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.7683599993794413	[997]	[693,673,823,573]	-8	hSpCas9	negative selection	6561114
113951560	113951583	2	-	27260156	CORL105	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.854460321216159	[203]	[126,113,135,151]	-9	hSpCas9	negative selection	6561115
113951550	113951573	2	+	27260156	HS294T	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.7759621714064169	[365]	[38,85,83,133]	-8	hSpCas9	negative selection	6618081
113916908	113916931	2	+	27260156	HS294T	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.3669542582954917	[745]	[212,179,226,286]	-5	hSpCas9	negative selection	6618082
113951714	113951737	2	+	27260156	HS294T	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.46867552999812334	[799]	[317,446,476,488]	6	hSpCas9	negative selection	6618083
113916991	113917014	2	-	27260156	HS294T	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.19313559207449382	[341]	[84,95,93,205]	-3	hSpCas9	negative selection	6682364
113951745	113951768	2	-	27260156	HS294T	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-1.0340608800779987	[997]	[140,115,255,258]	-9	hSpCas9	negative selection	6682365
113951560	113951583	2	-	27260156	HS294T	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.4240441063053417	[203]	[23,17,38,38]	-9	hSpCas9	negative selection	6682366
113951550	113951573	2	+	27260156	HCC44	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-1.408799529521471	[365]	[190,106,136,192]	-9	hSpCas9	negative selection	6739332
113916908	113916931	2	+	27260156	HCC44	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.9470253902566228	[745]	[590,318,431,434]	-8	hSpCas9	negative selection	6739333
113951714	113951737	2	+	27260156	HCC44	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.03713800132013301	[799]	[627,1142,1002,887]	0	hSpCas9	negative selection	6739334
113916991	113917014	2	-	27260156	HCC44	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.7038076922346854	[341]	[358,151,278,189]	-7	hSpCas9	negative selection	6803615
113951745	113951768	2	-	27260156	HCC44	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-2.143451391736712	[997]	[387,201,292,165]	-9	hSpCas9	negative selection	6803616
113951560	113951583	2	-	27260156	HCC44	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-3.174508099228656	[203]	[32,17,26,25]	-9	hSpCas9	negative selection	6803617
113951550	113951573	2	+	27260156	G402	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.22263599075077434	[365]	[261,344,608,297]	-3	hSpCas9	negative selection	6860583
113916908	113916931	2	+	27260156	G402	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.7678425224658947	[745]	[774,568,526,312]	-7	hSpCas9	negative selection	6860584
113951714	113951737	2	+	27260156	G402	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.2551428291049396	[799]	[1343,1389,1252,728]	3	hSpCas9	negative selection	6860585
113916991	113917014	2	-	27260156	G402	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	0.2096330082741323	[341]	[606,386,594,357]	2	hSpCas9	negative selection	6924866
113951745	113951768	2	-	27260156	G402	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.9296121013076997	[997]	[857,741,620,383]	-8	hSpCas9	negative selection	6924867
113951560	113951583	2	-	27260156	G402	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.132075392953893	[203]	[114,159,136,47]	-8	hSpCas9	negative selection	6924868
113951550	113951573	2	+	27260156	L33	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.4249095561989469	[365]	[290,86,188,285]	-7	hSpCas9	negative selection	6981834
113916908	113916931	2	+	27260156	L33	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.03924346613273988	[745]	[656,295,476,766]	-1	hSpCas9	negative selection	6981835
113951714	113951737	2	+	27260156	L33	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.497189337596734	[799]	[1047,482,714,1153]	8	hSpCas9	negative selection	6981836
113916991	113917014	2	-	27260156	L33	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.02418163328139178	[341]	[353,164,198,271]	0	hSpCas9	negative selection	7046117
113951745	113951768	2	-	27260156	L33	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.18429728615844565	[997]	[1001,360,537,771]	-4	hSpCas9	negative selection	7046118
113951560	113951583	2	-	27260156	L33	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.5831604547107225	[203]	[164,41,79,148]	-8	hSpCas9	negative selection	7046119
113951550	113951573	2	+	27260156	K562	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.34682060730866904	[365]	[113,120,78,641]	-4	hSpCas9	negative selection	7103085
113916908	113916931	2	+	27260156	K562	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.07895580038335481	[745]	[536,768,302,866]	-1	hSpCas9	negative selection	7103086
113951714	113951737	2	+	27260156	K562	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.27759245698490176	[799]	[820,655,835,1084]	3	hSpCas9	negative selection	7103087
113916991	113917014	2	-	27260156	K562	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	0.22346335335194667	[341]	[420,471,231,307]	2	hSpCas9	negative selection	7167368
113951745	113951768	2	-	27260156	K562	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-1.0341345568086913	[997]	[512,546,326,361]	-8	hSpCas9	negative selection	7167369
113951560	113951583	2	-	27260156	K562	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-2.2373655277444096	[203]	[84,31,11,28]	-9	hSpCas9	negative selection	7167370
113951550	113951573	2	+	27260156	HT29	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-1.313587242211321	[365]	[189,156,154,207]	-9	hSpCas9	negative selection	7224336
113916908	113916931	2	+	27260156	HT29	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-1.157286018742181	[745]	[399,444,381,399]	-9	hSpCas9	negative selection	7224337
113951714	113951737	2	+	27260156	HT29	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.1329408249281384	[799]	[1263,1152,964,916]	2	hSpCas9	negative selection	7224338
113916991	113917014	2	-	27260156	HT29	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.21933895354866906	[341]	[318,388,363,353]	-4	hSpCas9	negative selection	7288619
113951745	113951768	2	-	27260156	HT29	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-1.5491925015162926	[997]	[424,611,320,325]	-9	hSpCas9	negative selection	7288620
113951560	113951583	2	-	27260156	HT29	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.2490358820406153	[203]	[128,58,125,100]	-9	hSpCas9	negative selection	7288621
113951550	113951573	2	+	27260156	MHHES1	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-1.0623648684674585	[365]	[319,204,189,106]	-9	hSpCas9	negative selection	7345587
113916908	113916931	2	+	27260156	MHHES1	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.6681741446761639	[745]	[549,654,615,341]	-8	hSpCas9	negative selection	7345588
113951714	113951737	2	+	27260156	MHHES1	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.18641458530490418	[799]	[1271,1065,1037,790]	3	hSpCas9	negative selection	7345589
113916991	113917014	2	-	27260156	MHHES1	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	0.09607118425924488	[341]	[729,295,352,308]	1	hSpCas9	negative selection	7409870
113951745	113951768	2	-	27260156	MHHES1	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.8821056123184816	[997]	[827,530,773,368]	-9	hSpCas9	negative selection	7409871
113951560	113951583	2	-	27260156	MHHES1	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.4803552949734202	[203]	[195,210,116,143]	-7	hSpCas9	negative selection	7409872
113951550	113951573	2	+	27260156	MEWO	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.6163092151044233	[365]	[248,228,196]	-8	hSpCas9	negative selection	7466838
113916908	113916931	2	+	27260156	MEWO	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.42169497463873384	[745]	[564,420,585]	-7	hSpCas9	negative selection	7466839
113951714	113951737	2	+	27260156	MEWO	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.0017336062888667625	[799]	[863,756,643]	0	hSpCas9	negative selection	7466840
113916991	113917014	2	-	27260156	MEWO	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.0668376696202172	[341]	[272,319,316]	-1	hSpCas9	negative selection	7531121
113951745	113951768	2	-	27260156	MEWO	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.9498558478696228	[997]	[530,522,404]	-9	hSpCas9	negative selection	7531122
113951560	113951583	2	-	27260156	MEWO	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.1890499385828606	[203]	[67,95,83]	-9	hSpCas9	negative selection	7531123
113951550	113951573	2	+	27260156	LNCAPCLONEFGC	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	0.2577971169941781	[365]	[430,345,530,299]	4	hSpCas9	negative selection	7588089
113916908	113916931	2	+	27260156	LNCAPCLONEFGC	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	0.11927729693580347	[745]	[635,821,877,616]	1	hSpCas9	negative selection	7588090
113951714	113951737	2	+	27260156	LNCAPCLONEFGC	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.3508499746317977	[799]	[818,793,1349,806]	5	hSpCas9	negative selection	7588091
113916991	113917014	2	-	27260156	LNCAPCLONEFGC	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.004455988366526831	[341]	[217,254,419,363]	0	hSpCas9	negative selection	7652372
113951745	113951768	2	-	27260156	LNCAPCLONEFGC	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.11266619007133749	[997]	[860,696,925,881]	-2	hSpCas9	negative selection	7652373
113951560	113951583	2	-	27260156	LNCAPCLONEFGC	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.32143200091612556	[203]	[96,119,145,230]	-5	hSpCas9	negative selection	7652374
113951550	113951573	2	+	27260156	PANC0327	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-1.4999773894457888	[365]	[144,107,56,152]	-9	hSpCas9	negative selection	7709340
113916908	113916931	2	+	27260156	PANC0327	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.9171490667518294	[745]	[350,257,552,253]	-8	hSpCas9	negative selection	7709341
113951714	113951737	2	+	27260156	PANC0327	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.18383860292951548	[799]	[860,576,630,458]	-3	hSpCas9	negative selection	7709342
113916991	113917014	2	-	27260156	PANC0327	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-1.2348941783161218	[341]	[148,74,189,110]	-9	hSpCas9	negative selection	7773623
113951745	113951768	2	-	27260156	PANC0327	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-2.1598860205775763	[997]	[248,80,317,164]	-9	hSpCas9	negative selection	7773624
113951560	113951583	2	-	27260156	PANC0327	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-2.362572767896672	[203]	[45,9,8,79]	-9	hSpCas9	negative selection	7773625
113951550	113951573	2	+	27260156	NCIH2009	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-1.7845238523098799	[365]	[173,153,121]	-9	hSpCas9	negative selection	7830591
113916908	113916931	2	+	27260156	NCIH2009	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.9116909084229785	[745]	[744,438,516]	-8	hSpCas9	negative selection	7830592
113951714	113951737	2	+	27260156	NCIH2009	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.18463067105664854	[799]	[1281,1221,1307]	2	hSpCas9	negative selection	7830593
113916991	113917014	2	-	27260156	NCIH2009	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.2338265047495368	[341]	[472,322,436]	-3	hSpCas9	negative selection	7894874
113951745	113951768	2	-	27260156	NCIH2009	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-1.9757238923699436	[997]	[472,317,295]	-9	hSpCas9	negative selection	7894875
113951560	113951583	2	-	27260156	NCIH2009	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.3341309429438977	[203]	[40,41,242]	-8	hSpCas9	negative selection	7894876
113951550	113951573	2	+	27260156	NCIH1373	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-1.628720484294551	[365]	[91,82,176,46]	-9	hSpCas9	negative selection	7951842
113916908	113916931	2	+	27260156	NCIH1373	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.7187321567755619	[745]	[602,447,311,184]	-6	hSpCas9	negative selection	7951843
113951714	113951737	2	+	27260156	NCIH1373	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.24167977178754962	[799]	[1136,1111,901,287]	2	hSpCas9	negative selection	7951844
113916991	113917014	2	-	27260156	NCIH1373	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.5062928063857958	[341]	[476,204,205,59]	-5	hSpCas9	negative selection	8016125
113951745	113951768	2	-	27260156	NCIH1373	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-2.1478875022510753	[997]	[281,207,170,95]	-9	hSpCas9	negative selection	8016126
113951560	113951583	2	-	27260156	NCIH1373	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.8739031313656991	[203]	[169,63,123,40]	-7	hSpCas9	negative selection	8016127
113951550	113951573	2	+	27260156	PATU8902	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-2.889931564083919	[365]	[101,32,89,39]	-9	hSpCas9	negative selection	8073093
113916908	113916931	2	+	27260156	PATU8902	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-1.2901721698855106	[745]	[650,538,139,438]	-8	hSpCas9	negative selection	8073094
113951714	113951737	2	+	27260156	PATU8902	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.0638401749409071	[799]	[1747,808,722,1516]	0	hSpCas9	negative selection	8073095
113916991	113917014	2	-	27260156	PATU8902	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-1.7140244249830892	[341]	[133,152,84,233]	-8	hSpCas9	negative selection	8137376
113951745	113951768	2	-	27260156	PATU8902	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-2.5232571873681895	[997]	[345,119,144,395]	-9	hSpCas9	negative selection	8137377
113951560	113951583	2	-	27260156	PATU8902	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.3211596087611008	[203]	[14,83,26,383]	-8	hSpCas9	negative selection	8137378
113951550	113951573	2	+	27260156	PANC1	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-1.0280680319895772	[365]	[129,165,139,176]	-8	hSpCas9	negative selection	8194344
113916908	113916931	2	+	27260156	PANC1	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.8125330750685819	[745]	[373,457,377,276]	-8	hSpCas9	negative selection	8194345
113951714	113951737	2	+	27260156	PANC1	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.16990200031706715	[799]	[435,782,745,522]	-3	hSpCas9	negative selection	8194346
113916991	113917014	2	-	27260156	PANC1	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.13253099700140214	[341]	[470,232,239,133]	-2	hSpCas9	negative selection	8258627
113951745	113951768	2	-	27260156	PANC1	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-1.8475990781341083	[997]	[290,304,176,194]	-9	hSpCas9	negative selection	8258628
113951560	113951583	2	-	27260156	PANC1	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-1.9827162757569758	[203]	[47,65,56,14]	-9	hSpCas9	negative selection	8258629
113951550	113951573	2	+	27260156	PANC0813	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-1.3209037279810385	[365]	[156,268,135,126]	-9	hSpCas9	negative selection	8315595
113916908	113916931	2	+	27260156	PANC0813	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.4450309512582672	[745]	[726,691,590,574]	-6	hSpCas9	negative selection	8315596
113951714	113951737	2	+	27260156	PANC0813	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.43145870236619843	[799]	[1477,1598,931,1085]	7	hSpCas9	negative selection	8315597
113916991	113917014	2	-	27260156	PANC0813	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.6613865782191286	[341]	[263,362,102,283]	-7	hSpCas9	negative selection	8379878
113951745	113951768	2	-	27260156	PANC0813	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.944100554257893	[997]	[706,578,618,543]	-8	hSpCas9	negative selection	8379879
113951560	113951583	2	-	27260156	PANC0813	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.469823388204774	[203]	[193,98,329,76]	-6	hSpCas9	negative selection	8379880
113951550	113951573	2	+	27260156	RDES	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.09755067908537585	[365]	[332,345,353,571]	-2	hSpCas9	negative selection	8436846
113916908	113916931	2	+	27260156	RDES	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.3072182259099748	[745]	[522,615,752,946]	-5	hSpCas9	negative selection	8436847
113951714	113951737	2	+	27260156	RDES	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.3063425050032891	[799]	[993,937,1171,1521]	5	hSpCas9	negative selection	8436848
113916991	113917014	2	-	27260156	RDES	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.03458245861782011	[341]	[236,437,330,572]	0	hSpCas9	negative selection	8501129
113951745	113951768	2	-	27260156	RDES	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.655851865912751	[997]	[676,628,813,805]	-8	hSpCas9	negative selection	8501130
113951560	113951583	2	-	27260156	RDES	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.8620791408575923	[203]	[125,90,164,136]	-8	hSpCas9	negative selection	8501131
113951550	113951573	2	+	27260156	PC3	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	0.021489826416279223	[365]	[179,334,819,378]	0	hSpCas9	negative selection	8558097
113916908	113916931	2	+	27260156	PC3	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.013993729351421402	[745]	[489,677,1252,762]	0	hSpCas9	negative selection	8558098
113951714	113951737	2	+	27260156	PC3	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.3019433641920932	[799]	[472,870,1539,1439]	6	hSpCas9	negative selection	8558099
113916991	113917014	2	-	27260156	PC3	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.06100882563224985	[341]	[160,365,560,355]	-1	hSpCas9	negative selection	8622380
113951745	113951768	2	-	27260156	PC3	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	0.0943657728397509	[997]	[624,1006,1719,1257]	2	hSpCas9	negative selection	8622381
113951560	113951583	2	-	27260156	PC3	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.4543633291563631	[203]	[119,161,238,98]	-8	hSpCas9	negative selection	8622382
113951550	113951573	2	+	27260156	PATU8988T	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.34273471357009977	[365]	[111,417,376,214]	-5	hSpCas9	negative selection	8679348
113916908	113916931	2	+	27260156	PATU8988T	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.6438186773829924	[745]	[542,615,387,300]	-7	hSpCas9	negative selection	8679349
113951714	113951737	2	+	27260156	PATU8988T	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.03041203360651701	[799]	[578,656,1123,643]	0	hSpCas9	negative selection	8679350
113916991	113917014	2	-	27260156	PATU8988T	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.41373441216338713	[341]	[138,195,345,309]	-6	hSpCas9	negative selection	8743631
113951745	113951768	2	-	27260156	PATU8988T	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-1.0895300823161118	[997]	[357,354,613,475]	-9	hSpCas9	negative selection	8743632
113951560	113951583	2	-	27260156	PATU8988T	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.9377957071837111	[203]	[205,36,79,80]	-8	hSpCas9	negative selection	8743633
113951550	113951573	2	+	27260156	T47D	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.17889723257230505	[365]	[280,396,350,478]	-4	hSpCas9	negative selection	8800599
113916908	113916931	2	+	27260156	T47D	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.34440365852440896	[745]	[752,574,670,750]	-6	hSpCas9	negative selection	8800600
113951714	113951737	2	+	27260156	T47D	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.20585376579489134	[799]	[1162,935,950,1269]	4	hSpCas9	negative selection	8800601
113916991	113917014	2	-	27260156	T47D	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.051971501228612604	[341]	[326,439,342,423]	-1	hSpCas9	negative selection	8864882
113951745	113951768	2	-	27260156	T47D	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.5258775945798385	[997]	[895,653,849,843]	-8	hSpCas9	negative selection	8864883
113951560	113951583	2	-	27260156	T47D	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.8865027739206113	[203]	[167,126,112,105]	-9	hSpCas9	negative selection	8864884
113951550	113951573	2	+	27260156	SU8686	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-1.908273229464142	[365]	[96,76,118,95]	-9	hSpCas9	negative selection	8921850
113916908	113916931	2	+	27260156	SU8686	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.7513580221916947	[745]	[509,396,326,528]	-8	hSpCas9	negative selection	8921851
113951714	113951737	2	+	27260156	SU8686	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.2890379171310826	[799]	[903,893,977,1137]	5	hSpCas9	negative selection	8921852
113916991	113917014	2	-	27260156	SU8686	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.6785700530023437	[341]	[125,256,174,305]	-7	hSpCas9	negative selection	8986133
113951745	113951768	2	-	27260156	SU8686	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-1.9383609197967493	[997]	[231,231,202,389]	-9	hSpCas9	negative selection	8986134
113951560	113951583	2	-	27260156	SU8686	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-2.2867316622334717	[203]	[48,56,31,20]	-9	hSpCas9	negative selection	8986135
113951550	113951573	2	+	27260156	SKES1	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.36174804102645475	[365]	[247,270,277,324]	-7	hSpCas9	negative selection	9043101
113916908	113916931	2	+	27260156	SKES1	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.3969966901635621	[745]	[593,494,629,533]	-7	hSpCas9	negative selection	9043102
113951714	113951737	2	+	27260156	SKES1	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.027673985420090363	[799]	[897,1041,677,683]	0	hSpCas9	negative selection	9043103
113916991	113917014	2	-	27260156	SKES1	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	0.02523793666484786	[341]	[383,362,197,437]	0	hSpCas9	negative selection	9107384
113951745	113951768	2	-	27260156	SKES1	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.35950751802124814	[997]	[851,841,616,801]	-7	hSpCas9	negative selection	9107385
113951560	113951583	2	-	27260156	SKES1	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.9220594804953741	[203]	[72,135,109,107]	-9	hSpCas9	negative selection	9107386
113951550	113951573	2	+	27260156	TOV112D	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.49912620351584114	[365]	[328,264,253,197]	-7	hSpCas9	negative selection	9164352
113916908	113916931	2	+	27260156	TOV112D	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.46449669094012613	[745]	[508,719,354,619]	-7	hSpCas9	negative selection	9164353
113951714	113951737	2	+	27260156	TOV112D	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	-0.11598591407440462	[799]	[796,844,858,492]	-2	hSpCas9	negative selection	9164354
113916991	113917014	2	-	27260156	TOV112D	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.05900005356397231	[341]	[347,304,167,484]	-1	hSpCas9	negative selection	9228635
113951745	113951768	2	-	27260156	TOV112D	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.6695928076670625	[997]	[470,797,460,805]	-8	hSpCas9	negative selection	9228636
113951560	113951583	2	-	27260156	TOV112D	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.5559308632848639	[203]	[165,66,122,182]	-8	hSpCas9	negative selection	9228637
113951550	113951573	2	+	27260156	TC71	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.3467631373968424	[365]	[344,236,272,383]	-7	hSpCas9	negative selection	9285603
113916908	113916931	2	+	27260156	TC71	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.24359894248511177	[745]	[697,500,695,813]	-6	hSpCas9	negative selection	9285604
113951714	113951737	2	+	27260156	TC71	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.11703321302161662	[799]	[929,946,878,967]	3	hSpCas9	negative selection	9285605
113916991	113917014	2	-	27260156	TC71	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.2530875413829605	[341]	[318,352,311,241]	-6	hSpCas9	negative selection	9349886
113951745	113951768	2	-	27260156	TC71	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.47330456455918757	[997]	[813,790,631,853]	-8	hSpCas9	negative selection	9349887
113951560	113951583	2	-	27260156	TC71	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.6829437015993651	[203]	[120,226,68,129]	-9	hSpCas9	negative selection	9349888
113951550	113951573	2	+	27260156	TC32	viability	TGTCAGACGTCCTCTCTACAAGG	ACTR3	ENSG00000115091	-0.29821728189586494	[365]	[227,183,403,355]	-5	hSpCas9	negative selection	9406854
113916908	113916931	2	+	27260156	TC32	viability	AAGTGGGTGATCAAGCTCAAAGG	ACTR3	ENSG00000115091	-0.4494276348417106	[745]	[520,339,688,571]	-7	hSpCas9	negative selection	9406855
113951714	113951737	2	+	27260156	TC32	viability	CACTAGAATATTGTCCTCTCTGG	ACTR3	ENSG00000115091	0.1738523212543126	[799]	[848,664,1079,855]	3	hSpCas9	negative selection	9406856
113916991	113917014	2	-	27260156	TC32	viability	CATACCTTTGTTGCATATGTAGG	ACTR3	ENSG00000115091	-0.47339538069101494	[341]	[316,116,219,291]	-7	hSpCas9	negative selection	9471137
113951745	113951768	2	-	27260156	TC32	viability	ACGTCCAAAGTCCCTGAACATGG	ACTR3	ENSG00000115091	-0.707223552395746	[997]	[596,374,738,658]	-8	hSpCas9	negative selection	9471138
113951560	113951583	2	-	27260156	TC32	viability	GCTATAAATACCTTGTAGAGAGG	ACTR3	ENSG00000115091	-0.8793929152459858	[203]	[72,59,203,112]	-9	hSpCas9	negative selection	9471139
113927339	113927362	2	+	27869803	HPAFII	viability after 27 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-2.979310141232815	[179]	[5,16,NaN]	-9	hSpCas9	negative selection	9571405
113927339	113927362	2	+	27869803	HPAFII	viability after 15 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-3.013948130190651	[179]	[10,31,NaN]	-9	hSpCas9	negative selection	9653854
113927339	113927362	2	+	27869803	ASPC1	viability after 36 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.015114541664947898	[610]	[298,243,120]	0	hSpCas9	negative selection	9736303
113927339	113927362	2	+	27869803	PATU8988S	viability after 35 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.2783615337165174	[431]	[124,161,NaN]	-3	hSpCas9	negative selection	9818752
113927339	113927362	2	+	27869803	PATU8988S	viability after 31 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	0.1285852763150516	[431]	[164,217,NaN]	1	hSpCas9	negative selection	9901201
113927339	113927362	2	+	27869803	HPAFII	viability after 35 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-2.9979025335361116	[179]	[1,21,NaN]	-8	hSpCas9	negative selection	9983650
113927339	113927362	2	+	27869803	HPAFII	viability after 31 days	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-4.537466495693051	[179]	[0,7,NaN]	-9	hSpCas9	negative selection	10066099
113913206	113913229	2	-	28162770	P31FUJ	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-1.1746992498508102	[145]	[75]	-7	hSpCas9	negative selection	10106522
113940072	113940095	2	+	28162770	P31FUJ	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-2.402727205856691	[35]	[7]	-8	hSpCas9	negative selection	10106523
113927339	113927362	2	+	28162770	P31FUJ	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.979515775132147	[98]	[58]	-6	hSpCas9	negative selection	10106524
113940060	113940083	2	+	28162770	P31FUJ	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	-0.5048817498511794	[511]	[423]	-4	hSpCas9	negative selection	10106525
113890288	113890311	2	+	28162770	P31FUJ	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.113220588661706	[242]	[131]	-7	hSpCas9	negative selection	10106526
113951800	113951823	2	+	28162770	P31FUJ	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.5855105704000622	[603]	[472]	-5	hSpCas9	negative selection	10106527
113951813	113951836	2	+	28162770	P31FUJ	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.33668334824125723	[474]	[441]	-3	hSpCas9	negative selection	10106528
113890269	113890292	2	+	28162770	P31FUJ	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.5053280592254703	[243]	[100]	-7	hSpCas9	negative selection	10106529
113890302	113890325	2	+	28162770	P31FUJ	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-1.8350426965673703	[251]	[82]	-8	hSpCas9	negative selection	10106530
113934336	113934359	2	+	28162770	P31FUJ	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-1.1569864227156383	[555]	[292]	-7	hSpCas9	negative selection	10106531
113913206	113913229	2	-	28162770	TF1	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10275888
113940072	113940095	2	+	28162770	TF1	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10275889
113927339	113927362	2	+	28162770	TF1	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10275890
113940060	113940083	2	+	28162770	TF1	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	NaN	[NaN]	[312]	1	hSpCas9	negative selection	10275891
113890288	113890311	2	+	28162770	TF1	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10275892
113951800	113951823	2	+	28162770	TF1	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	NaN	[NaN]	[401]	1	hSpCas9	negative selection	10275893
113951813	113951836	2	+	28162770	TF1	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10275894
113890269	113890292	2	+	28162770	TF1	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10275895
113890302	113890325	2	+	28162770	TF1	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10275896
113934336	113934359	2	+	28162770	TF1	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10275897
113913206	113913229	2	-	28162770	SKM1	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-1.9919266994643179	[53]	[23]	-8	hSpCas9	negative selection	10445254
113940072	113940095	2	+	28162770	SKM1	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-0.3074285251922473	[6]	[9]	-3	hSpCas9	negative selection	10445255
113927339	113927362	2	+	28162770	SKM1	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	0.26546114322833403	[23]	[50]	2	hSpCas9	negative selection	10445256
113940060	113940083	2	+	28162770	SKM1	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.0630057796880632	[123]	[228]	0	hSpCas9	negative selection	10445257
113890288	113890311	2	+	28162770	SKM1	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.121561979880913	[63]	[51]	-7	hSpCas9	negative selection	10445258
113951800	113951823	2	+	28162770	SKM1	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	0.21362221170871587	[159]	[327]	2	hSpCas9	negative selection	10445259
113951813	113951836	2	+	28162770	SKM1	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.520620980538729	[98]	[121]	-4	hSpCas9	negative selection	10445260
113890269	113890292	2	+	28162770	SKM1	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.576889200185474	[53]	[31]	-8	hSpCas9	negative selection	10445261
113890302	113890325	2	+	28162770	SKM1	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-2.1876511703386856	[66]	[25]	-8	hSpCas9	negative selection	10445262
113934336	113934359	2	+	28162770	SKM1	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-1.4367115421372136	[97]	[63]	-7	hSpCas9	negative selection	10445263
113913206	113913229	2	-	28162770	SKM1	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-1.9919266994643179	[53]	[23]	-8	hSpCas9	negative selection	10614620
113940072	113940095	2	+	28162770	SKM1	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-0.3074285251922473	[6]	[9]	-3	hSpCas9	negative selection	10614621
113927339	113927362	2	+	28162770	SKM1	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	0.26546114322833403	[23]	[50]	2	hSpCas9	negative selection	10614622
113940060	113940083	2	+	28162770	SKM1	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.0630057796880632	[123]	[228]	0	hSpCas9	negative selection	10614623
113890288	113890311	2	+	28162770	SKM1	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.121561979880913	[63]	[51]	-7	hSpCas9	negative selection	10614624
113951800	113951823	2	+	28162770	SKM1	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	0.21362221170871587	[159]	[327]	2	hSpCas9	negative selection	10614625
113951813	113951836	2	+	28162770	SKM1	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.520620980538729	[98]	[121]	-4	hSpCas9	negative selection	10614626
113890269	113890292	2	+	28162770	SKM1	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.576889200185474	[53]	[31]	-8	hSpCas9	negative selection	10614627
113890302	113890325	2	+	28162770	SKM1	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-2.1876511703386856	[66]	[25]	-8	hSpCas9	negative selection	10614628
113934336	113934359	2	+	28162770	SKM1	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-1.4367115421372136	[97]	[63]	-7	hSpCas9	negative selection	10614629
113913206	113913229	2	-	28162770	PL21	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-2.0311859316171352	[215]	[22]	-8	hSpCas9	negative selection	10783986
113940072	113940095	2	+	28162770	PL21	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	0.4938708175460307	[30]	[18]	4	hSpCas9	negative selection	10783987
113927339	113927362	2	+	28162770	PL21	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.6596827274624194	[97]	[26]	-4	hSpCas9	negative selection	10783988
113940060	113940083	2	+	28162770	PL21	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.14931535541163776	[519]	[250]	1	hSpCas9	negative selection	10783989
113890288	113890311	2	+	28162770	PL21	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-2.2167001274235094	[266]	[24]	-8	hSpCas9	negative selection	10783990
113951800	113951823	2	+	28162770	PL21	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.712166324604282	[733]	[194]	-5	hSpCas9	negative selection	10783991
113951813	113951836	2	+	28162770	PL21	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.47793229062331766	[255]	[79]	-3	hSpCas9	negative selection	10783992
113890269	113890292	2	+	28162770	PL21	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.374769221567913	[142]	[23]	-7	hSpCas9	negative selection	10783993
113890302	113890325	2	+	28162770	PL21	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-5.307655025709376	[181]	[1]	-9	hSpCas9	negative selection	10783994
113934336	113934359	2	+	28162770	PL21	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	0.06381814327653973	[243]	[110]	0	hSpCas9	negative selection	10783995
113913206	113913229	2	-	28162770	P31FUJ	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-1.1746992498508102	[145]	[75]	-7	hSpCas9	negative selection	10953352
113940072	113940095	2	+	28162770	P31FUJ	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-2.402727205856691	[35]	[7]	-8	hSpCas9	negative selection	10953353
113927339	113927362	2	+	28162770	P31FUJ	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.979515775132147	[98]	[58]	-6	hSpCas9	negative selection	10953354
113940060	113940083	2	+	28162770	P31FUJ	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	-0.5048817498511794	[511]	[423]	-4	hSpCas9	negative selection	10953355
113890288	113890311	2	+	28162770	P31FUJ	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.113220588661706	[242]	[131]	-7	hSpCas9	negative selection	10953356
113951800	113951823	2	+	28162770	P31FUJ	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.5855105704000622	[603]	[472]	-5	hSpCas9	negative selection	10953357
113951813	113951836	2	+	28162770	P31FUJ	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.33668334824125723	[474]	[441]	-3	hSpCas9	negative selection	10953358
113890269	113890292	2	+	28162770	P31FUJ	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.5053280592254703	[243]	[100]	-7	hSpCas9	negative selection	10953359
113890302	113890325	2	+	28162770	P31FUJ	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-1.8350426965673703	[251]	[82]	-8	hSpCas9	negative selection	10953360
113934336	113934359	2	+	28162770	P31FUJ	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-1.1569864227156383	[555]	[292]	-7	hSpCas9	negative selection	10953361
113913206	113913229	2	-	28162770	OCIAML5	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-0.5301384759766344	[99]	[124]	-4	hSpCas9	negative selection	11122718
113940072	113940095	2	+	28162770	OCIAML5	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	0.3889415286397977	[10]	[25]	3	hSpCas9	negative selection	11122719
113927339	113927362	2	+	28162770	OCIAML5	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.2526045004477255	[65]	[49]	-6	hSpCas9	negative selection	11122720
113940060	113940083	2	+	28162770	OCIAML5	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	-0.022582961960374348	[304]	[541]	0	hSpCas9	negative selection	11122721
113890288	113890311	2	+	28162770	OCIAML5	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-0.611058471360202	[120]	[142]	-4	hSpCas9	negative selection	11122722
113951800	113951823	2	+	28162770	OCIAML5	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.1524293159164256	[414]	[673]	-1	hSpCas9	negative selection	11122723
113951813	113951836	2	+	28162770	OCIAML5	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	0.377904042767219	[216]	[508]	3	hSpCas9	negative selection	11122724
113890269	113890292	2	+	28162770	OCIAML5	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-2.3374933980342387	[125]	[44]	-8	hSpCas9	negative selection	11122725
113890302	113890325	2	+	28162770	OCIAML5	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-0.9934224201095384	[149]	[135]	-6	hSpCas9	negative selection	11122726
113934336	113934359	2	+	28162770	OCIAML5	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.4939100935170433	[290]	[372]	-3	hSpCas9	negative selection	11122727
113913206	113913229	2	-	28162770	EOL1	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-1.4616694516718078	[412]	[78]	-7	hSpCas9	negative selection	11292084
113940072	113940095	2	+	28162770	EOL1	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-0.8948799827876446	[59]	[16]	-6	hSpCas9	negative selection	11292085
113927339	113927362	2	+	28162770	EOL1	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.0816573779561738	[232]	[57]	-6	hSpCas9	negative selection	11292086
113940060	113940083	2	+	28162770	EOL1	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	-0.11974150457426203	[859]	[416]	-1	hSpCas9	negative selection	11292087
113890288	113890311	2	+	28162770	EOL1	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.259876799566893	[499]	[109]	-7	hSpCas9	negative selection	11292088
113951800	113951823	2	+	28162770	EOL1	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.11329098417706529	[1042]	[507]	-1	hSpCas9	negative selection	11292089
113951813	113951836	2	+	28162770	EOL1	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.5348838470667627	[351]	[127]	-4	hSpCas9	negative selection	11292090
113890269	113890292	2	+	28162770	EOL1	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-2.3910940604693964	[228]	[22]	-8	hSpCas9	negative selection	11292091
113890302	113890325	2	+	28162770	EOL1	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-2.6965485152043347	[282]	[22]	-9	hSpCas9	negative selection	11292092
113934336	113934359	2	+	28162770	EOL1	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.5034056155935946	[373]	[138]	-4	hSpCas9	negative selection	11292093
113913206	113913229	2	-	28162770	MOLM13	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-2.32218754908119	[248]	[35]	-8	hSpCas9	negative selection	11461450
113940072	113940095	2	+	28162770	MOLM13	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-1.5093905419553377	[62]	[15]	-6	hSpCas9	negative selection	11461451
113927339	113927362	2	+	28162770	MOLM13	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.7775866529049106	[146]	[61]	-4	hSpCas9	negative selection	11461452
113940060	113940083	2	+	28162770	MOLM13	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	-0.8881814750238385	[790]	[308]	-5	hSpCas9	negative selection	11461453
113890288	113890311	2	+	28162770	MOLM13	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.5931400518529806	[337]	[80]	-7	hSpCas9	negative selection	11461454
113951800	113951823	2	+	28162770	MOLM13	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.15306555276969824	[831]	[540]	-1	hSpCas9	negative selection	11461455
113951813	113951836	2	+	28162770	MOLM13	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.8216172356504061	[395]	[161]	-4	hSpCas9	negative selection	11461456
113890269	113890292	2	+	28162770	MOLM13	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-2.532110618455421	[199]	[24]	-8	hSpCas9	negative selection	11461457
113890302	113890325	2	+	28162770	MOLM13	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-7.775284601928373	[302]	[0]	-9	hSpCas9	negative selection	11461458
113934336	113934359	2	+	28162770	MOLM13	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-1.7201003356597249	[441]	[96]	-7	hSpCas9	negative selection	11461459
113913206	113913229	2	-	28162770	HEL	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-1.3425646567929412	[292]	[73]	-6	hSpCas9	negative selection	11630816
113940072	113940095	2	+	28162770	HEL	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-0.9817520329074365	[36]	[11]	-6	hSpCas9	negative selection	11630817
113927339	113927362	2	+	28162770	HEL	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	1.4283392014174399	[104]	[180]	9	hSpCas9	negative selection	11630818
113940060	113940083	2	+	28162770	HEL	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.058764140315319624	[729]	[486]	0	hSpCas9	negative selection	11630819
113890288	113890311	2	+	28162770	HEL	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.0609934589830898	[328]	[100]	-6	hSpCas9	negative selection	11630820
113951800	113951823	2	+	28162770	HEL	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	0.35651963874576365	[827]	[678]	3	hSpCas9	negative selection	11630821
113951813	113951836	2	+	28162770	HEL	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.1967964958063969	[373]	[208]	-1	hSpCas9	negative selection	11630822
113890269	113890292	2	+	28162770	HEL	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.2755180185581068	[222]	[58]	-6	hSpCas9	negative selection	11630823
113890302	113890325	2	+	28162770	HEL	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-2.1337551263524865	[184]	[26]	-8	hSpCas9	negative selection	11630824
113934336	113934359	2	+	28162770	HEL	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.41234872810385176	[346]	[166]	-3	hSpCas9	negative selection	11630825
113913206	113913229	2	-	28162770	MV411	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-2.2761244052742375	[206]	[35]	-8	hSpCas9	negative selection	11800182
113940072	113940095	2	+	28162770	MV411	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-4.840025290467564	[33]	[0]	-9	hSpCas9	negative selection	11800183
113927339	113927362	2	+	28162770	MV411	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.3202469585065453	[82]	[27]	-7	hSpCas9	negative selection	11800184
113940060	113940083	2	+	28162770	MV411	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.24458355372762242	[505]	[504]	2	hSpCas9	negative selection	11800185
113890288	113890311	2	+	28162770	MV411	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-2.582637447774912	[255]	[35]	-9	hSpCas9	negative selection	11800186
113951800	113951823	2	+	28162770	MV411	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.14783669367463848	[579]	[440]	-1	hSpCas9	negative selection	11800187
113951813	113951836	2	+	28162770	MV411	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-1.442394067792336	[270]	[83]	-7	hSpCas9	negative selection	11800188
113890269	113890292	2	+	28162770	MV411	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.1376843705917812	[174]	[66]	-6	hSpCas9	negative selection	11800189
113890302	113890325	2	+	28162770	MV411	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-1.5901319843218369	[192]	[53]	-7	hSpCas9	negative selection	11800190
113934336	113934359	2	+	28162770	MV411	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.4797137535564753	[292]	[176]	-4	hSpCas9	negative selection	11800191
113913206	113913229	2	-	28162770	MONOMAC1	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-2.9097548949790824	[117]	[17]	-9	hSpCas9	negative selection	11969548
113940072	113940095	2	+	28162770	MONOMAC1	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-2.004391769117158	[27]	[7]	-8	hSpCas9	negative selection	11969549
113927339	113927362	2	+	28162770	MONOMAC1	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-1.2819257446460668	[69]	[32]	-7	hSpCas9	negative selection	11969550
113940060	113940083	2	+	28162770	MONOMAC1	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	-0.28033949375411527	[302]	[285]	-2	hSpCas9	negative selection	11969551
113890288	113890311	2	+	28162770	MONOMAC1	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.559606926444262	[161]	[62]	-8	hSpCas9	negative selection	11969552
113951800	113951823	2	+	28162770	MONOMAC1	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	-0.2450840214666623	[518]	[501]	-2	hSpCas9	negative selection	11969553
113951813	113951836	2	+	28162770	MONOMAC1	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.440442446144415	[218]	[184]	-4	hSpCas9	negative selection	11969554
113890269	113890292	2	+	28162770	MONOMAC1	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-2.664162857486852	[93]	[16]	-9	hSpCas9	negative selection	11969555
113890302	113890325	2	+	28162770	MONOMAC1	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-3.1648564413104037	[132]	[16]	-9	hSpCas9	negative selection	11969556
113934336	113934359	2	+	28162770	MONOMAC1	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.6979350829922354	[149]	[105]	-5	hSpCas9	negative selection	11969557
113913206	113913229	2	-	28162770	OCIAML2	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-1.4892455034095082	[38]	[76]	-7	hSpCas9	negative selection	12138914
113940072	113940095	2	+	28162770	OCIAML2	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-0.6341285575250408	[6]	[24]	-5	hSpCas9	negative selection	12138915
113927339	113927362	2	+	28162770	OCIAML2	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.6108074832904216	[26]	[97]	-4	hSpCas9	negative selection	12138916
113940060	113940083	2	+	28162770	OCIAML2	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.4504746295860582	[100]	[764]	4	hSpCas9	negative selection	12138917
113890288	113890311	2	+	28162770	OCIAML2	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	-1.4366824933188238	[41]	[85]	-7	hSpCas9	negative selection	12138918
113951800	113951823	2	+	28162770	OCIAML2	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	0.16632731311725646	[108]	[677]	1	hSpCas9	negative selection	12138919
113951813	113951836	2	+	28162770	OCIAML2	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.8076648125197319	[65]	[208]	-5	hSpCas9	negative selection	12138920
113890269	113890292	2	+	28162770	OCIAML2	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-2.965394516991739	[30]	[21]	-9	hSpCas9	negative selection	12138921
113890302	113890325	2	+	28162770	OCIAML2	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-1.7145554081282506	[44]	[75]	-8	hSpCas9	negative selection	12138922
113934336	113934359	2	+	28162770	OCIAML2	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.8672887952061505	[51]	[157]	-6	hSpCas9	negative selection	12138923
113913206	113913229	2	-	28162770	OCIAML3	viability	CAGGAAGGGATGATAAACTGTGG	ACTR3	ENSG00000115091	-1.0769492041048103	[57]	[82]	-6	hSpCas9	negative selection	12308280
113940072	113940095	2	+	28162770	OCIAML3	viability	ACAATCCTTGGAAACTGCTAAGG	ACTR3	ENSG00000115091	-1.1345760216868657	[7]	[10]	-7	hSpCas9	negative selection	12308281
113927339	113927362	2	+	28162770	OCIAML3	viability	TAATAGTGGCCAATCCGCCATGG	ACTR3	ENSG00000115091	-0.4171298782400841	[22]	[51]	-3	hSpCas9	negative selection	12308282
113940060	113940083	2	+	28162770	OCIAML3	viability	AATCCCTCCAGAACAATCCTTGG	ACTR3	ENSG00000115091	0.556552036251218	[124]	[554]	5	hSpCas9	negative selection	12308283
113890288	113890311	2	+	28162770	OCIAML3	viability	ACGGCTGCCGGCCTGTGTGGTGG	ACTR3	ENSG00000115091	0.28903621332998763	[60]	[224]	2	hSpCas9	negative selection	12308284
113951800	113951823	2	+	28162770	OCIAML3	viability	TGCCCGGCTGAAATTAAGTGAGG	ACTR3	ENSG00000115091	0.11349835336837888	[187]	[613]	1	hSpCas9	negative selection	12308285
113951813	113951836	2	+	28162770	OCIAML3	viability	TTAAGTGAGGAATTGAGTGGTGG	ACTR3	ENSG00000115091	-0.4627631070459106	[104]	[229]	-4	hSpCas9	negative selection	12308286
113890269	113890292	2	+	28162770	OCIAML3	viability	CGAGGAGGAAGATGGCGGGACGG	ACTR3	ENSG00000115091	-1.679737514350047	[51]	[48]	-8	hSpCas9	negative selection	12308287
113890302	113890325	2	+	28162770	OCIAML3	viability	GTGTGGTGGACTGTGGCACGGGG	ACTR3	ENSG00000115091	-1.2668428970706538	[54]	[68]	-7	hSpCas9	negative selection	12308288
113934336	113934359	2	+	28162770	OCIAML3	viability	ACCGGTACGGTAATAGACAGTGG	ACTR3	ENSG00000115091	-0.7732322025042377	[106]	[188]	-5	hSpCas9	negative selection	12308289