| 150293357 | 150293380 | 7 | - | 26472758 | Jiyoye | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.2643747811068493 | [381] | [345] | 2 | hSpCas9 | negative selection | 2220 | 150289494 | 150289517 | 7 | - | 26472758 | Jiyoye | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | 1.1330004180668791 | [77] | [128] | 7 | hSpCas9 | negative selection | 2221 | 150286469 | 150286492 | 7 | - | 26472758 | Jiyoye | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.12686298424024445 | [503] | [414] | 1 | hSpCas9 | negative selection | 2223 | 150284815 | 150284838 | 7 | + | 26472758 | Jiyoye | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | -0.5532962543074891 | [143] | [73] | -4 | hSpCas9 | negative selection | 2224 | 150286458 | 150286481 | 7 | + | 26472758 | Jiyoye | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.7018622378065382 | [555] | [681] | 5 | hSpCas9 | negative selection | 2225 | 150284824 | 150284847 | 7 | - | 26472758 | Jiyoye | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | -0.21889232254495583 | [266] | [172] | -1 | hSpCas9 | negative selection | 2226 | 150284761 | 150284784 | 7 | + | 26472758 | Jiyoye | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | 0.13587335968847922 | [139] | [115] | 1 | hSpCas9 | negative selection | 2227 | 150248987 | 150249010 | 7 | + | 26472758 | Jiyoye | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.1610147942364757 | [50] | [42] | 1 | hSpCas9 | negative selection | 2228 | 150284742 | 150284765 | 7 | + | 26472758 | Jiyoye | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -0.6434506915640945 | [28] | [13] | -4 | hSpCas9 | negative selection | 2229 | 150293387 | 150293410 | 7 | + | 26472758 | Jiyoye | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.003757719440233759 | [116] | [87] | 0 | hSpCas9 | negative selection | 2231 | 150293357 | 150293380 | 7 | - | 26472758 | KBM7 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.7881607320462705 | [1442,1389] | [1407,925] | 8 | hSpCas9 | negative selection | 193338 | 150289494 | 150289517 | 7 | - | 26472758 | KBM7 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -0.11899350837954134 | [594,597] | [257,260] | -1 | hSpCas9 | negative selection | 193339 | 150286469 | 150286492 | 7 | - | 26472758 | KBM7 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.009199576732326631 | [1026,814] | [445,420] | 0 | hSpCas9 | negative selection | 193341 | 150284815 | 150284838 | 7 | + | 26472758 | KBM7 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 0.3076155849880525 | [325,184] | [178,114] | 3 | hSpCas9 | negative selection | 193342 | 150286458 | 150286481 | 7 | + | 26472758 | KBM7 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.01901286068755148 | [2944,2278] | [1408,1077] | 0 | hSpCas9 | negative selection | 193343 | 150284824 | 150284847 | 7 | - | 26472758 | KBM7 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.7433994539103946 | [629,326] | [426,311] | 7 | hSpCas9 | negative selection | 193344 | 150284761 | 150284784 | 7 | + | 26472758 | KBM7 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -0.2988734351788606 | [534,604] | [195,241] | -3 | hSpCas9 | negative selection | 193345 | 150248987 | 150249010 | 7 | + | 26472758 | KBM7 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | -0.21525982746262629 | [294,340] | [94,161] | -2 | hSpCas9 | negative selection | 193346 | 150284742 | 150284765 | 7 | + | 26472758 | KBM7 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -0.47681487718666027 | [236,232] | [103,57] | -4 | hSpCas9 | negative selection | 193347 | 150293387 | 150293410 | 7 | + | 26472758 | KBM7 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.14196277141031066 | [551,448] | [257,170] | -1 | hSpCas9 | negative selection | 193349 | 150293357 | 150293380 | 7 | - | 26472758 | Raji | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.4093069546009882 | [609] | [187] | 4 | hSpCas9 | negative selection | 384456 | 150289494 | 150289517 | 7 | - | 26472758 | Raji | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -1.2823872052948144 | [282] | [26] | -7 | hSpCas9 | negative selection | 384457 | 150286469 | 150286492 | 7 | - | 26472758 | Raji | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.4699536147583079 | [475] | [152] | 4 | hSpCas9 | negative selection | 384459 | 150284815 | 150284838 | 7 | + | 26472758 | Raji | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | -0.5248846801259135 | [185] | [29] | -4 | hSpCas9 | negative selection | 384460 | 150286458 | 150286481 | 7 | + | 26472758 | Raji | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.5189404659174817 | [1244] | [413] | 5 | hSpCas9 | negative selection | 384461 | 150284824 | 150284847 | 7 | - | 26472758 | Raji | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.7854554404862372 | [249] | [99] | 7 | hSpCas9 | negative selection | 384462 | 150284761 | 150284784 | 7 | + | 26472758 | Raji | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -0.6230094048691205 | [291] | [43] | -5 | hSpCas9 | negative selection | 384463 | 150248987 | 150249010 | 7 | + | 26472758 | Raji | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.9796279881752268 | [117] | [53] | 8 | hSpCas9 | negative selection | 384464 | 150284742 | 150284765 | 7 | + | 26472758 | Raji | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | 0.996959545679949 | [94] | [43] | 8 | hSpCas9 | negative selection | 384465 | 150293387 | 150293410 | 7 | + | 26472758 | Raji | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.7893471940146974 | [282] | [37] | -6 | hSpCas9 | negative selection | 384467 | 150293357 | 150293380 | 7 | - | 26472758 | K562 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.3720190831923882 | [1102] | [1204] | 3 | hSpCas9 | negative selection | 575574 | 150289494 | 150289517 | 7 | - | 26472758 | K562 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -0.7874067181889508 | [549] | [268] | -5 | hSpCas9 | negative selection | 575575 | 150286469 | 150286492 | 7 | - | 26472758 | K562 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.5931830075261246 | [979] | [1247] | 5 | hSpCas9 | negative selection | 575577 | 150284815 | 150284838 | 7 | + | 26472758 | K562 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 0.03593014500024669 | [326] | [282] | 0 | hSpCas9 | negative selection | 575578 | 150286458 | 150286481 | 7 | + | 26472758 | K562 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.527312109369726 | [1947] | [2369] | 4 | hSpCas9 | negative selection | 575579 | 150284824 | 150284847 | 7 | - | 26472758 | K562 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.9188163119695476 | [343] | [548] | 7 | hSpCas9 | negative selection | 575580 | 150284761 | 150284784 | 7 | + | 26472758 | K562 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -0.8539191915268456 | [515] | [240] | -5 | hSpCas9 | negative selection | 575581 | 150248987 | 150249010 | 7 | + | 26472758 | K562 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.35989594508638284 | [215] | [233] | 3 | hSpCas9 | negative selection | 575582 | 150284742 | 150284765 | 7 | + | 26472758 | K562 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -1.2692850898848875 | [236] | [82] | -6 | hSpCas9 | negative selection | 575583 | 150293387 | 150293410 | 7 | + | 26472758 | K562 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.17061877161239708 | [315] | [236] | -1 | hSpCas9 | negative selection | 575585 | 150250478 | 150250501 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGGCTTGAGCCACTGCGCCCGG | ACTR3C | ENSG00000106526 | 1.5878752533514864 | [74,11] | [3,54] | 6 | dCas9-VP64 | positive selection | 2388866 | 150303071 | 150303094 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CACTGATCTATGATGGGAAATGG | ACTR3C | ENSG00000106526 | -1.5927751416608547 | [30,195] | [7,7] | -8 | dCas9-VP64 | positive selection | 2404613 | 150303127 | 150303150 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CTTAGTCATCCCTGTCCACAAGG | ACTR3C | ENSG00000106526 | 0.3751239650463316 | [477,1237] | [52,455] | 1 | dCas9-VP64 | positive selection | 2404615 | 150303101 | 150303124 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCTGGGAAATGCTTTTTTCTGGG | ACTR3C | ENSG00000106526 | -0.9213893799890789 | [40,160] | [10,11] | -5 | dCas9-VP64 | positive selection | 2404616 | 150292690 | 150292713 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TTTCTCCATGTTGGTCAGGCAGG | ACTR3C | ENSG00000106526 | -2.2958931667653815 | [393,165] | [8,14] | -9 | dCas9-VP64 | positive selection | 2417402 | 150284518 | 150284541 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGAGTCTTGCTCTGTCACCCGGG | ACTR3C | ENSG00000106526 | 0.18377208399179143 | [26,157] | [32,11] | 0 | dCas9-VP64 | positive selection | 2421952 | 150314906 | 150314929 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CACACCACTGCACTCCAGCCAGG | ACTR3C | ENSG00000106526 | -0.6897978744123147 | [436,52] | [50,12] | -4 | dCas9-VP64 | positive selection | 2457805 | 150320528 | 150320551 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TGAGGTGGGTGGATCACTTGAAG | ACTR3C | ENSG00000106526 | 0.9269503688862448 | [9,0] | [1,1] | 4 | dCas9-VP64 | positive selection | 2463082 | 150250478 | 150250501 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGGCTTGAGCCACTGCGCCCGG | ACTR3C | ENSG00000106526 | 0.16456713163057946 | [58,38] | [18,15] | 1 | dCas9-VP64 | positive selection | 2484121 | 150303071 | 150303094 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CACTGATCTATGATGGGAAATGG | ACTR3C | ENSG00000106526 | -0.4270622768778525 | [292,146] | [32,71] | -4 | dCas9-VP64 | positive selection | 2499868 | 150303127 | 150303150 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CTTAGTCATCCCTGTCCACAAGG | ACTR3C | ENSG00000106526 | -0.5510704931020898 | [177,149] | [21,49] | -5 | dCas9-VP64 | positive selection | 2499870 | 150303101 | 150303124 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCTGGGAAATGCTTTTTTCTGGG | ACTR3C | ENSG00000106526 | 1.2959701851260212 | [298,181] | [39,337] | 7 | dCas9-VP64 | positive selection | 2499871 | 150292690 | 150292713 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TTTCTCCATGTTGGTCAGGCAGG | ACTR3C | ENSG00000106526 | 0.6223741115754664 | [126,133] | [38,89] | 4 | dCas9-VP64 | positive selection | 2512657 | 150284518 | 150284541 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGAGTCTTGCTCTGTCACCCGGG | ACTR3C | ENSG00000106526 | 1.2364773942763427 | [105,126] | [117,63] | 7 | dCas9-VP64 | positive selection | 2517207 | 150314906 | 150314929 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CACACCACTGCACTCCAGCCAGG | ACTR3C | ENSG00000106526 | 0.2274396231328648 | [285,212] | [141,51] | 1 | dCas9-VP64 | positive selection | 2553060 | 150320528 | 150320551 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TGAGGTGGGTGGATCACTTGAAG | ACTR3C | ENSG00000106526 | -0.7008385215102662 | [31,39] | [9,2] | -6 | dCas9-VP64 | positive selection | 2558337 | 150293340 | 150293363 | 7 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | ACGGGGATAGTCATTGACAGCGG | ACTR3C | ENSG00000106526 | -0.9699055614197601 | [3,3] | [1,0] | -9 | hSpCas9 | positive selection | 2968760 | 150293311 | 150293334 | 7 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AGTCACCCATGTTATCCCAGTGG | ACTR3C | ENSG00000106526 | 0.04141793474683442 | [4,4] | [3,3] | 0 | hSpCas9 | positive selection | 2968761 | 150293359 | 150293382 | 7 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AGTGGGTGAACGTACATTAACGG | ACTR3C | ENSG00000106526 | 0.1825330339171456 | [3,3] | [2,3] | 4 | hSpCas9 | positive selection | 2968762 | 150293357 | 150293380 | 7 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.7693376068906427 | [2,3] | [2,0] | -8 | hSpCas9 | positive selection | 2968763 | 150293340 | 150293363 | 7 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | ACGGGGATAGTCATTGACAGCGG | ACTR3C | ENSG00000106526 | 0.14475357050286133 | [3,3] | [3,1] | 2 | hSpCas9 | positive selection | 3036618 | 150293311 | 150293334 | 7 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AGTCACCCATGTTATCCCAGTGG | ACTR3C | ENSG00000106526 | -0.598969740801514 | [4,4] | [3,0] | -8 | hSpCas9 | positive selection | 3036619 | 150293359 | 150293382 | 7 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AGTGGGTGAACGTACATTAACGG | ACTR3C | ENSG00000106526 | -0.7057672827367562 | [3,3] | [2,0] | -8 | hSpCas9 | positive selection | 3036620 | 150293357 | 150293380 | 7 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.007034588033786676 | [2,2] | [2,1] | 0 | hSpCas9 | positive selection | 3036621 | 150295271 | 150295294 | 7 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | -0.9946898389218665 | [283,325] | [0,0] | -6 | hSpCas9 | positive selection | 3335449 | 150293404 | 150293427 | 7 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TCTCCAGGCAGTGCTGGCCTTGG | ACTR3C | ENSG00000106526 | 0.23965655169614475 | [173,214] | [0,1] | 1 | hSpCas9 | positive selection | 3335450 | 150293305 | 150293328 | 7 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.02850752094995433 | [149,149] | [0,0] | 0 | hSpCas9 | positive selection | 3354698 | 150289574 | 150289597 | 7 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | TAGGCAGAAGGTTATGTAATTGG | ACTR3C | ENSG00000106526 | -0.10899600279998067 | [164,164] | [0,0] | 0 | hSpCas9 | positive selection | 3354699 | 150289544 | 150289567 | 7 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | ATCAAACACATCCCGATTGCAGG | ACTR3C | ENSG00000106526 | 0.21293209208738176 | [131,131] | [0,0] | 1 | hSpCas9 | positive selection | 3354700 | 150293340 | 150293363 | 7 | - | 26780180 | HT29 | viability (Avana library 4 designs) | ACGGGGATAGTCATTGACAGCGG | ACTR3C | ENSG00000106526 | 2.95809340943203 | [] | [] | 8 | hSpCas9 | negative selection | 3404710 | 150293311 | 150293334 | 7 | - | 26780180 | HT29 | viability (Avana library 4 designs) | AGTCACCCATGTTATCCCAGTGG | ACTR3C | ENSG00000106526 | 1.08640118047075 | [] | [] | 4 | hSpCas9 | negative selection | 3404711 | 150293359 | 150293382 | 7 | - | 26780180 | HT29 | viability (Avana library 4 designs) | AGTGGGTGAACGTACATTAACGG | ACTR3C | ENSG00000106526 | 1.96752478875598 | [] | [] | 7 | hSpCas9 | negative selection | 3404712 | 150293357 | 150293380 | 7 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 1.8614277496283 | [] | [] | 7 | hSpCas9 | negative selection | 3404713 | 150293357 | 150293380 | 7 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 2.27744598754424 | [] | [] | 3 | hSpCas9 | negative selection | 3476379 | 150293359 | 150293382 | 7 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGTGGGTGAACGTACATTAACGG | ACTR3C | ENSG00000106526 | 5.43370676129558 | [] | [] | 8 | hSpCas9 | negative selection | 3476380 | 150293340 | 150293363 | 7 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | ACGGGGATAGTCATTGACAGCGG | ACTR3C | ENSG00000106526 | -0.93570043792373 | [] | [] | -1 | hSpCas9 | negative selection | 3476381 | 150293311 | 150293334 | 7 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGTCACCCATGTTATCCCAGTGG | ACTR3C | ENSG00000106526 | -1.27547718867625 | [] | [] | -1 | hSpCas9 | negative selection | 3476382 | 150293306 | 150293329 | 7 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTTACCACTGGGATAACATGGG | ACTR3C | ENSG00000106526 | -4.77246687795585 | [] | [] | -5 | hSpCas9 | negative selection | 3476383 | 150289467 | 150289490 | 7 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TCTCCAGTGACTGCTCAGGAGGG | ACTR3C | ENSG00000106526 | 0 | [] | [] | 0 | hSpCas9 | negative selection | 3476384 | 150293357 | 150293380 | 7 | - | 26780180 | A375 | viability (Avana lentiGuide) | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.86076842573122 | [] | [] | 1 | hSpCas9 | negative selection | 3585038 | 150293359 | 150293382 | 7 | - | 26780180 | A375 | viability (Avana lentiGuide) | AGTGGGTGAACGTACATTAACGG | ACTR3C | ENSG00000106526 | -1.90583529753276 | [] | [] | -3 | hSpCas9 | negative selection | 3585039 | 150293340 | 150293363 | 7 | - | 26780180 | A375 | viability (Avana lentiGuide) | ACGGGGATAGTCATTGACAGCGG | ACTR3C | ENSG00000106526 | -1.35139028177871 | [] | [] | -2 | hSpCas9 | negative selection | 3585040 | 150293311 | 150293334 | 7 | - | 26780180 | A375 | viability (Avana lentiGuide) | AGTCACCCATGTTATCCCAGTGG | ACTR3C | ENSG00000106526 | 11.1443776772729 | [] | [] | 7 | hSpCas9 | negative selection | 3585041 | 150293306 | 150293329 | 7 | + | 26780180 | A375 | viability (Avana lentiGuide) | GCTTACCACTGGGATAACATGGG | ACTR3C | ENSG00000106526 | 3.40118357164619 | [] | [] | 3 | hSpCas9 | negative selection | 3585042 | 150289467 | 150289490 | 7 | + | 26780180 | A375 | viability (Avana lentiGuide) | TCTCCAGTGACTGCTCAGGAGGG | ACTR3C | ENSG00000106526 | 0 | [] | [] | 0 | hSpCas9 | negative selection | 3585043 | 150293357 | 150293380 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.0320459835208865 | [4] | [5,3] | 0 | hSpCas9 | positive selection | 3693697 | 150293359 | 150293382 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGTGGGTGAACGTACATTAACGG | ACTR3C | ENSG00000106526 | 0.17104281105940441 | [5] | [6,5] | 4 | hSpCas9 | positive selection | 3693698 | 150293340 | 150293363 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | ACGGGGATAGTCATTGACAGCGG | ACTR3C | ENSG00000106526 | -0.5309380189522054 | [4] | [3,1] | -6 | hSpCas9 | positive selection | 3693699 | 150293311 | 150293334 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGTCACCCATGTTATCCCAGTGG | ACTR3C | ENSG00000106526 | 0.038294488468310975 | [5] | [5,5] | 1 | hSpCas9 | positive selection | 3693700 | 150293306 | 150293329 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTTACCACTGGGATAACATGGG | ACTR3C | ENSG00000106526 | -0.5971572453006364 | [4] | [2,2] | -7 | hSpCas9 | positive selection | 3693701 | 150289467 | 150289490 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TCTCCAGTGACTGCTCAGGAGGG | ACTR3C | ENSG00000106526 | 0.05947611385637419 | [0] | [0,0] | 1 | hSpCas9 | positive selection | 3693702 | 150293357 | 150293380 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.15452164031040908 | [5] | [3,4] | -2 | hSpCas9 | positive selection | 3802304 | 150293359 | 150293382 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGTGGGTGAACGTACATTAACGG | ACTR3C | ENSG00000106526 | -0.6597156340737482 | [5] | [2,2] | -7 | hSpCas9 | positive selection | 3802305 | 150293340 | 150293363 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | ACGGGGATAGTCATTGACAGCGG | ACTR3C | ENSG00000106526 | -0.013937593761785605 | [5] | [1,6] | 0 | hSpCas9 | positive selection | 3802306 | 150293311 | 150293334 | 7 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGTCACCCATGTTATCCCAGTGG | ACTR3C | ENSG00000106526 | -0.027261704187396735 | [5] | [4,4] | 0 | hSpCas9 | positive selection | 3802307 | 150293306 | 150293329 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTTACCACTGGGATAACATGGG | ACTR3C | ENSG00000106526 | -0.6439916554432239 | [5] | [2,2] | -7 | hSpCas9 | positive selection | 3802308 | 150289467 | 150289490 | 7 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TCTCCAGTGACTGCTCAGGAGGG | ACTR3C | ENSG00000106526 | 0.24644513604583196 | [0] | [0,0] | 6 | hSpCas9 | positive selection | 3802309 | 150293305 | 150293328 | 7 | + | 26780180 | A375 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 1.02898996869436 | [] | [] | 5 | hSpCas9 | negative selection | 3910910 | 150295271 | 150295294 | 7 | - | 26780180 | A375 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 1.12972554730499 | [] | [] | 5 | hSpCas9 | negative selection | 3910911 | 150293305 | 150293328 | 7 | + | 26780180 | HT29 | viability (GeCKOv2 library) | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 1.28328870945955 | [] | [] | 6 | hSpCas9 | negative selection | 4018876 | 150295271 | 150295294 | 7 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 1.52724519792988 | [] | [] | 7 | hSpCas9 | negative selection | 4018877 | 150295271 | 150295294 | 7 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.25380072718238605 | [4] | [4,3] | 5 | hSpCas9 | positive selection | 4254368 | 150295253 | 150295276 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.3869790085671959 | [4] | [3,1] | -7 | hSpCas9 | positive selection | 4254369 | 150293305 | 150293328 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.3793472126002118 | [2] | [2,0] | -7 | hSpCas9 | positive selection | 4318651 | 150289464 | 150289486 | 7 | + | 27760321 | OCIAML3 | viability | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -0.20892978342842394 | [1040,879] | [601,706] | -2 | hSpCas9 | negative selection | 4375951 | 150289533 | 150289555 | 7 | + | 27760321 | OCIAML3 | viability | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -1.6671778987401353 | [62,50] | [16,9] | -8 | hSpCas9 | negative selection | 4375952 | 150293306 | 150293328 | 7 | + | 27760321 | OCIAML3 | viability | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.49214093106189816 | [337,270] | [163,173] | -5 | hSpCas9 | negative selection | 4375953 | 150293334 | 150293356 | 7 | - | 27760321 | OCIAML3 | viability | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -1.5433059605506438 | [287,277] | [69,83] | -8 | hSpCas9 | negative selection | 4375954 | 150293357 | 150293379 | 7 | - | 27760321 | OCIAML3 | viability | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -1.1221953847333812 | [188,184] | [39,102] | -7 | hSpCas9 | negative selection | 4375955 | 150289464 | 150289486 | 7 | + | 27760321 | OCIAML2 | viability | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -0.5249498965714743 | [1040,879] | [465,632] | -5 | hSpCas9 | negative selection | 4459414 | 150289533 | 150289555 | 7 | + | 27760321 | OCIAML2 | viability | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -1.2641305759466572 | [62,50] | [25,9] | -8 | hSpCas9 | negative selection | 4459415 | 150293306 | 150293328 | 7 | + | 27760321 | OCIAML2 | viability | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.4847809228974561 | [337,270] | [130,232] | -5 | hSpCas9 | negative selection | 4459416 | 150293334 | 150293356 | 7 | - | 27760321 | OCIAML2 | viability | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -1.1883414551056641 | [287,277] | [110,86] | -8 | hSpCas9 | negative selection | 4459417 | 150293357 | 150293379 | 7 | - | 27760321 | OCIAML2 | viability | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.12843942519756557 | [188,184] | [179,146] | 1 | hSpCas9 | negative selection | 4459418 | 150289464 | 150289486 | 7 | + | 27760321 | MV411 | viability | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -0.2391208522827205 | [1040,879] | [405,728] | -2 | hSpCas9 | negative selection | 4542877 | 150289533 | 150289555 | 7 | + | 27760321 | MV411 | viability | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | 2.5402063063243636 | [62,50] | [0,542] | 9 | hSpCas9 | negative selection | 4542878 | 150293306 | 150293328 | 7 | + | 27760321 | MV411 | viability | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -2.1896316921445447 | [337,270] | [36,53] | -8 | hSpCas9 | negative selection | 4542879 | 150293334 | 150293356 | 7 | - | 27760321 | MV411 | viability | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -2.592886286015875 | [287,277] | [44,9] | -9 | hSpCas9 | negative selection | 4542880 | 150293357 | 150293379 | 7 | - | 27760321 | MV411 | viability | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -4.271938313212388 | [188,184] | [9,0] | -9 | hSpCas9 | negative selection | 4542881 | 150289464 | 150289486 | 7 | + | 27760321 | HL60 | viability | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -0.7087345402813472 | [1040,879] | [439,518] | -6 | hSpCas9 | negative selection | 4626340 | 150289533 | 150289555 | 7 | + | 27760321 | HL60 | viability | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -1.5149637575075934 | [62,50] | [22,8] | -8 | hSpCas9 | negative selection | 4626341 | 150293306 | 150293328 | 7 | + | 27760321 | HL60 | viability | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.36572290777865346 | [337,270] | [406,224] | 4 | hSpCas9 | negative selection | 4626342 | 150293334 | 150293356 | 7 | - | 27760321 | HL60 | viability | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -0.567654974762855 | [287,277] | [164,146] | -6 | hSpCas9 | negative selection | 4626343 | 150293357 | 150293379 | 7 | - | 27760321 | HL60 | viability | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.2290521825900953 | [188,184] | [151,107] | -3 | hSpCas9 | negative selection | 4626344 | 150289464 | 150289486 | 7 | + | 27760321 | HT1080 | viability | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -2.0824660541094855 | [879,686] | [119,22] | -6 | hSpCas9 | negative selection | 4709803 | 150289533 | 150289555 | 7 | + | 27760321 | HT1080 | viability | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -2.327123831640484 | [50,39] | [5,0] | -6 | hSpCas9 | negative selection | 4709804 | 150293306 | 150293328 | 7 | + | 27760321 | HT1080 | viability | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.2269841952426166 | [270,211] | [33,134] | -1 | hSpCas9 | negative selection | 4709805 | 150293334 | 150293356 | 7 | - | 27760321 | HT1080 | viability | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -2.015454308366076 | [277,216] | [21,26] | -6 | hSpCas9 | negative selection | 4709806 | 150293357 | 150293379 | 7 | - | 27760321 | HT1080 | viability | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -1.7303391233807346 | [184,144] | [36,0] | -6 | hSpCas9 | negative selection | 4709807 | 150289464 | 150289486 | 7 | + | 27760321 | HT29 | viability after 7 days | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | 0.37834447656098313 | [879,686] | [1638,948,1382] | 6 | hSpCas9 | negative selection | 4793266 | 150289533 | 150289555 | 7 | + | 27760321 | HT29 | viability after 7 days | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -0.5733831843374935 | [50,39] | [21,7,83] | -7 | hSpCas9 | negative selection | 4793267 | 150293306 | 150293328 | 7 | + | 27760321 | HT29 | viability after 7 days | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.27961191141509356 | [270,211] | [408,188,192] | -4 | hSpCas9 | negative selection | 4793268 | 150293334 | 150293356 | 7 | - | 27760321 | HT29 | viability after 7 days | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -0.9572744941876596 | [277,216] | [162,249,80] | -8 | hSpCas9 | negative selection | 4793269 | 150293357 | 150293379 | 7 | - | 27760321 | HT29 | viability after 7 days | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.8215892798756916 | [184,144] | [155,147,62] | -8 | hSpCas9 | negative selection | 4793270 | 150289464 | 150289486 | 7 | + | 27760321 | HT29 | viability after 25 days | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -0.5539468352357345 | [879,686] | [418,758,668] | -5 | hSpCas9 | negative selection | 4876729 | 150289533 | 150289555 | 7 | + | 27760321 | HT29 | viability after 25 days | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -1.509892633493144 | [50,39] | [23,6,23] | -7 | hSpCas9 | negative selection | 4876730 | 150293306 | 150293328 | 7 | + | 27760321 | HT29 | viability after 25 days | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.28514744248230695 | [270,211] | [231,184,265] | -3 | hSpCas9 | negative selection | 4876731 | 150293334 | 150293356 | 7 | - | 27760321 | HT29 | viability after 25 days | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -1.0038667561612449 | [277,216] | [63,194,171] | -6 | hSpCas9 | negative selection | 4876732 | 150293357 | 150293379 | 7 | - | 27760321 | HT29 | viability after 25 days | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.148738965385119 | [184,144] | [139,98,284] | -1 | hSpCas9 | negative selection | 4876733 | 150289464 | 150289486 | 7 | + | 27760321 | HT29 | viability after 22 days | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -0.03260787156690381 | [879,686] | [969,933,748] | 0 | hSpCas9 | negative selection | 4960192 | 150289533 | 150289555 | 7 | + | 27760321 | HT29 | viability after 22 days | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -1.1138845219791689 | [50,39] | [50,18,1] | -7 | hSpCas9 | negative selection | 4960193 | 150293306 | 150293328 | 7 | + | 27760321 | HT29 | viability after 22 days | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.48448140088911373 | [270,211] | [190,203,203] | -4 | hSpCas9 | negative selection | 4960194 | 150293334 | 150293356 | 7 | - | 27760321 | HT29 | viability after 22 days | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -0.9017288793068834 | [277,216] | [74,185,200] | -6 | hSpCas9 | negative selection | 4960195 | 150293357 | 150293379 | 7 | - | 27760321 | HT29 | viability after 22 days | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.02072006068554244 | [184,144] | [169,144,266] | 0 | hSpCas9 | negative selection | 4960196 | 150289464 | 150289486 | 7 | + | 27760321 | HT29 | viability after 19 days | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | 0.005008824933462774 | [879,686] | [724,1060,892] | 0 | hSpCas9 | negative selection | 5043655 | 150289533 | 150289555 | 7 | + | 27760321 | HT29 | viability after 19 days | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -1.6820701475051987 | [50,39] | [32,16,0] | -7 | hSpCas9 | negative selection | 5043656 | 150293306 | 150293328 | 7 | + | 27760321 | HT29 | viability after 19 days | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.3815904973009251 | [270,211] | [184,151,292] | -4 | hSpCas9 | negative selection | 5043657 | 150293334 | 150293356 | 7 | - | 27760321 | HT29 | viability after 19 days | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -0.9021172266345168 | [277,216] | [173,193,90] | -6 | hSpCas9 | negative selection | 5043658 | 150293357 | 150293379 | 7 | - | 27760321 | HT29 | viability after 19 days | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.6113142151471382 | [184,144] | [112,92,161] | -5 | hSpCas9 | negative selection | 5043659 | 150289464 | 150289486 | 7 | + | 27760321 | HT29 | viability after 16 days | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -0.037613040347231674 | [879,686] | [972,1053,540] | 0 | hSpCas9 | negative selection | 5127118 | 150289533 | 150289555 | 7 | + | 27760321 | HT29 | viability after 16 days | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -1.3039690321949822 | [50,39] | [25,34,0] | -7 | hSpCas9 | negative selection | 5127119 | 150293306 | 150293328 | 7 | + | 27760321 | HT29 | viability after 16 days | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.8994428015370327 | [270,211] | [167,135,132] | -6 | hSpCas9 | negative selection | 5127120 | 150293334 | 150293356 | 7 | - | 27760321 | HT29 | viability after 16 days | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -0.5801275524296658 | [277,216] | [155,218,176] | -5 | hSpCas9 | negative selection | 5127121 | 150293357 | 150293379 | 7 | - | 27760321 | HT29 | viability after 16 days | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.689932484802529 | [184,144] | [119,71,152] | -6 | hSpCas9 | negative selection | 5127122 | 150289464 | 150289486 | 7 | + | 27760321 | HT29 | viability after 13 days | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | 0.05626162937893153 | [879,686] | [1224,996,631] | 0 | hSpCas9 | negative selection | 5210581 | 150289533 | 150289555 | 7 | + | 27760321 | HT29 | viability after 13 days | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -2.458500264598965 | [50,39] | [0,20,6] | -9 | hSpCas9 | negative selection | 5210582 | 150293306 | 150293328 | 7 | + | 27760321 | HT29 | viability after 13 days | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.17703765129219295 | [270,211] | [297,139,301] | -2 | hSpCas9 | negative selection | 5210583 | 150293334 | 150293356 | 7 | - | 27760321 | HT29 | viability after 13 days | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -0.893484121423304 | [277,216] | [108,169,182] | -7 | hSpCas9 | negative selection | 5210584 | 150293357 | 150293379 | 7 | - | 27760321 | HT29 | viability after 13 days | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.04534992345080924 | [184,144] | [240,104,208] | 0 | hSpCas9 | negative selection | 5210585 | 150289464 | 150289486 | 7 | + | 27760321 | HT29 | viability after 10 days | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -0.22354829598340453 | [879,686] | [861,1019,640] | -3 | hSpCas9 | negative selection | 5294044 | 150289533 | 150289555 | 7 | + | 27760321 | HT29 | viability after 10 days | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -2.2913924851536907 | [50,39] | [2,18,12] | -9 | hSpCas9 | negative selection | 5294045 | 150293306 | 150293328 | 7 | + | 27760321 | HT29 | viability after 10 days | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.11460618575296211 | [270,211] | [403,422,158] | 1 | hSpCas9 | negative selection | 5294046 | 150293334 | 150293356 | 7 | - | 27760321 | HT29 | viability after 10 days | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | -0.3972100114393281 | [277,216] | [398,122,179] | -5 | hSpCas9 | negative selection | 5294047 | 150293357 | 150293379 | 7 | - | 27760321 | HT29 | viability after 10 days | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.44589891798255166 | [184,144] | [139,99,210] | -5 | hSpCas9 | negative selection | 5294048 | 150289464 | 150289486 | 7 | + | 27760321 | MOLM13 | viability | CGGTCTCCAGTGACTGCTCAGG | ACTR3C | ENSG00000106526 | -0.775103155018855 | [1040,879] | [368,269] | -5 | hSpCas9 | negative selection | 5377507 | 150289533 | 150289555 | 7 | + | 27760321 | MOLM13 | viability | TAATATCTCTACCTGCAATCGG | ACTR3C | ENSG00000106526 | -4.999405760933459 | [62,50] | [0,0] | -9 | hSpCas9 | negative selection | 5377508 | 150293306 | 150293328 | 7 | + | 27760321 | MOLM13 | viability | GCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.17980159874540402 | [337,270] | [166,136] | -1 | hSpCas9 | negative selection | 5377509 | 150293334 | 150293356 | 7 | - | 27760321 | MOLM13 | viability | TAGTCATTGACAGCGGAGATGG | ACTR3C | ENSG00000106526 | 0.01533042474299895 | [287,277] | [266,71] | 0 | hSpCas9 | negative selection | 5377510 | 150293357 | 150293379 | 7 | - | 27760321 | MOLM13 | viability | GGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -4.312851435156722 | [188,184] | [0,8] | -9 | hSpCas9 | negative selection | 5377511 | 150295271 | 150295294 | 7 | - | 27260156 | BXPC3 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.24030631508571143 | [1119] | [1270,1095,1343,1905] | 5 | hSpCas9 | negative selection | 5526828 | 150295253 | 150295276 | 7 | + | 27260156 | BXPC3 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.37753739450768875 | [1755] | [1443,1266,1314,1649] | -7 | hSpCas9 | negative selection | 5526829 | 150293305 | 150293328 | 7 | + | 27260156 | BXPC3 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.17587292804870938 | [405] | [257,348,401,524] | -4 | hSpCas9 | negative selection | 5591111 | 150295271 | 150295294 | 7 | - | 27260156 | A673 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.183047125849368 | [1119] | [1780,1386,1408,1562] | 4 | hSpCas9 | negative selection | 5648079 | 150295253 | 150295276 | 7 | + | 27260156 | A673 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.2786621265602576 | [1755] | [2058,1513,1556,1870] | -6 | hSpCas9 | negative selection | 5648080 | 150293305 | 150293328 | 7 | + | 27260156 | A673 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.015831936598645374 | [405] | [512,414,528,518] | 0 | hSpCas9 | negative selection | 5712362 | 150295271 | 150295294 | 7 | - | 27260156 | A375 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.6856628208739344 | [1119] | [1998,2245,2446,1774] | 8 | hSpCas9 | negative selection | 5769330 | 150295253 | 150295276 | 7 | + | 27260156 | A375 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.5008496150973032 | [1755] | [1282,1515,1772,1251] | -6 | hSpCas9 | negative selection | 5769331 | 150293305 | 150293328 | 7 | + | 27260156 | A375 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.5143941170913399 | [405] | [442,461,269,187] | -6 | hSpCas9 | negative selection | 5833613 | 150295271 | 150295294 | 7 | - | 27260156 | COLO741 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.2846946078767896 | [1119] | [1983,1815,1466] | 6 | hSpCas9 | negative selection | 5890581 | 150295253 | 150295276 | 7 | + | 27260156 | COLO741 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.2203630833496173 | [1755] | [1995,1717,2054] | -5 | hSpCas9 | negative selection | 5890582 | 150293305 | 150293328 | 7 | + | 27260156 | COLO741 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.15432845723984653 | [405] | [511,504,389] | -3 | hSpCas9 | negative selection | 5954864 | 150295271 | 150295294 | 7 | - | 27260156 | CAL120 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.594101824472437 | [1119] | [1833,2382,2053] | 8 | hSpCas9 | negative selection | 6011832 | 150295253 | 150295276 | 7 | + | 27260156 | CAL120 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.12076352165410742 | [1755] | [2232,1997,1833] | -2 | hSpCas9 | negative selection | 6011833 | 150293305 | 150293328 | 7 | + | 27260156 | CAL120 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.5546483524297934 | [405] | [1165,733,395] | 8 | hSpCas9 | negative selection | 6076115 | 150295271 | 150295294 | 7 | - | 27260156 | CADOES1 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.42995619218845604 | [1119] | [1382,1390,1392,1447] | 7 | hSpCas9 | negative selection | 6133083 | 150295253 | 150295276 | 7 | + | 27260156 | CADOES1 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.3525984325363942 | [1755] | [1176,1222,1369,1348] | -6 | hSpCas9 | negative selection | 6133084 | 150293305 | 150293328 | 7 | + | 27260156 | CADOES1 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.12903912488733213 | [405] | [272,301,339,470] | -2 | hSpCas9 | negative selection | 6197366 | 150295271 | 150295294 | 7 | - | 27260156 | EWS502 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.28277930233580384 | [1119] | [1221,1169,1565,1879] | 5 | hSpCas9 | negative selection | 6254334 | 150295253 | 150295276 | 7 | + | 27260156 | EWS502 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.25273095646291033 | [1755] | [1414,1462,1574,1825] | -4 | hSpCas9 | negative selection | 6254335 | 150293305 | 150293328 | 7 | + | 27260156 | EWS502 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.11863409528823986 | [405] | [539,319,597,401] | 2 | hSpCas9 | negative selection | 6318617 | 150295271 | 150295294 | 7 | - | 27260156 | EW8 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.18412695229767628 | [1119] | [1250,1043,813,1073] | 3 | hSpCas9 | negative selection | 6375585 | 150295253 | 150295276 | 7 | + | 27260156 | EW8 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.36337483190576614 | [1755] | [1090,997,1214,1096] | -6 | hSpCas9 | negative selection | 6375586 | 150293305 | 150293328 | 7 | + | 27260156 | EW8 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.3631802523081702 | [405] | [343,183,230,276] | -6 | hSpCas9 | negative selection | 6439868 | 150295271 | 150295294 | 7 | - | 27260156 | CORL105 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.2763245817585944 | [1119] | [1561,1599,1924,1316] | 5 | hSpCas9 | negative selection | 6496836 | 150295253 | 150295276 | 7 | + | 27260156 | CORL105 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.4249053423546798 | [1755] | [1464,1355,1857,1497] | -7 | hSpCas9 | negative selection | 6496837 | 150293305 | 150293328 | 7 | + | 27260156 | CORL105 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.5878717593855554 | [405] | [353,370,244,283] | -8 | hSpCas9 | negative selection | 6561119 | 150295271 | 150295294 | 7 | - | 27260156 | HS294T | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.2974369036366047 | [1119] | [412,626,534,565] | 4 | hSpCas9 | negative selection | 6618087 | 150295253 | 150295276 | 7 | + | 27260156 | HS294T | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.3500793317037274 | [1755] | [448,472,604,627] | -5 | hSpCas9 | negative selection | 6618088 | 150293305 | 150293328 | 7 | + | 27260156 | HS294T | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.47362006739317697 | [405] | [96,94,133,130] | -6 | hSpCas9 | negative selection | 6682370 | 150295271 | 150295294 | 7 | - | 27260156 | HCC44 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.3336921551415175 | [1119] | [1559,1669,1874,1310] | 5 | hSpCas9 | negative selection | 6739338 | 150295253 | 150295276 | 7 | + | 27260156 | HCC44 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.3243409189179711 | [1755] | [2093,1266,1941,1194] | -5 | hSpCas9 | negative selection | 6739339 | 150293305 | 150293328 | 7 | + | 27260156 | HCC44 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.13642819536315032 | [405] | [683,530,500,316] | 2 | hSpCas9 | negative selection | 6803621 | 150295271 | 150295294 | 7 | - | 27260156 | G402 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.531798674949481 | [1119] | [2189,2166,1700,1883] | 6 | hSpCas9 | negative selection | 6860589 | 150295253 | 150295276 | 7 | + | 27260156 | G402 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.6494970492622134 | [1755] | [1565,1898,890,1171] | -7 | hSpCas9 | negative selection | 6860590 | 150293305 | 150293328 | 7 | + | 27260156 | G402 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.1578184904724058 | [405] | [454,563,423,344] | -2 | hSpCas9 | negative selection | 6924872 | 150295271 | 150295294 | 7 | - | 27260156 | L33 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.1848546147099952 | [1119] | [1181,555,758,1346] | 4 | hSpCas9 | negative selection | 6981840 | 150295253 | 150295276 | 7 | + | 27260156 | L33 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.13753986101116888 | [1755] | [1324,756,948,1707] | -3 | hSpCas9 | negative selection | 6981841 | 150293305 | 150293328 | 7 | + | 27260156 | L33 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.15645098909514663 | [405] | [349,177,216,327] | -4 | hSpCas9 | negative selection | 7046123 | 150295271 | 150295294 | 7 | - | 27260156 | K562 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.3143128135960547 | [1119] | [1371,1270,938,1354] | 4 | hSpCas9 | negative selection | 7103091 | 150295253 | 150295276 | 7 | + | 27260156 | K562 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.42748279762099095 | [1755] | [1453,946,1300,963] | -5 | hSpCas9 | negative selection | 7103092 | 150293305 | 150293328 | 7 | + | 27260156 | K562 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.23388740295111626 | [405] | [437,598,238,426] | 3 | hSpCas9 | negative selection | 7167374 | 150295271 | 150295294 | 7 | - | 27260156 | HT29 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.26837908542839295 | [1119] | [1791,1907,1671,1257] | 5 | hSpCas9 | negative selection | 7224342 | 150295253 | 150295276 | 7 | + | 27260156 | HT29 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.22525485439507564 | [1755] | [1762,1932,1977,1643] | -4 | hSpCas9 | negative selection | 7224343 | 150293305 | 150293328 | 7 | + | 27260156 | HT29 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.10682292840631877 | [405] | [418,511,365,525] | -2 | hSpCas9 | negative selection | 7288625 | 150295271 | 150295294 | 7 | - | 27260156 | MHHES1 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.4668726220917081 | [1119] | [2085,1992,1664,1348] | 8 | hSpCas9 | negative selection | 7345593 | 150295253 | 150295276 | 7 | + | 27260156 | MHHES1 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.005278319307922441 | [1755] | [2257,2161,2118,1470] | 0 | hSpCas9 | negative selection | 7345594 | 150293305 | 150293328 | 7 | + | 27260156 | MHHES1 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.35939969650466563 | [405] | [364,268,358,404] | -6 | hSpCas9 | negative selection | 7409876 | 150295271 | 150295294 | 7 | - | 27260156 | MEWO | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.18202966761228256 | [1119] | [1357,1136,1103] | 4 | hSpCas9 | negative selection | 7466844 | 150295253 | 150295276 | 7 | + | 27260156 | MEWO | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.1967189864028287 | [1755] | [1730,1359,1266] | -4 | hSpCas9 | negative selection | 7466845 | 150293305 | 150293328 | 7 | + | 27260156 | MEWO | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.3550012133435192 | [405] | [363,269,269] | -6 | hSpCas9 | negative selection | 7531127 | 150295271 | 150295294 | 7 | - | 27260156 | LNCAPCLONEFGC | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.32567025394246496 | [1119] | [1233,1255,1440,1180] | 5 | hSpCas9 | negative selection | 7588095 | 150295253 | 150295276 | 7 | + | 27260156 | LNCAPCLONEFGC | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.6093112188949406 | [1755] | [922,1122,1243,906] | -7 | hSpCas9 | negative selection | 7588096 | 150293305 | 150293328 | 7 | + | 27260156 | LNCAPCLONEFGC | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.5877258561656549 | [405] | [260,225,280,216] | -7 | hSpCas9 | negative selection | 7652378 | 150295271 | 150295294 | 7 | - | 27260156 | PANC0327 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.2867145584194726 | [1119] | [955,893,1657,1366] | 4 | hSpCas9 | negative selection | 7709346 | 150295253 | 150295276 | 7 | + | 27260156 | PANC0327 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.2945818848404309 | [1755] | [1482,935,1585,1142] | -4 | hSpCas9 | negative selection | 7709347 | 150293305 | 150293328 | 7 | + | 27260156 | PANC0327 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.05819172719841981 | [405] | [572,304,273,374] | 0 | hSpCas9 | negative selection | 7773629 | 150295271 | 150295294 | 7 | - | 27260156 | NCIH2009 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.6139547447475546 | [1119] | [3047,1713,2559] | 8 | hSpCas9 | negative selection | 7830597 | 150295253 | 150295276 | 7 | + | 27260156 | NCIH2009 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.7051330201727 | [1755] | [1462,1439,1601] | -7 | hSpCas9 | negative selection | 7830598 | 150293305 | 150293328 | 7 | + | 27260156 | NCIH2009 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.6308992175583309 | [405] | [429,360,319] | -7 | hSpCas9 | negative selection | 7894880 | 150295271 | 150295294 | 7 | - | 27260156 | NCIH1373 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.8028949067487887 | [1119] | [2661,2009,2258,496] | 7 | hSpCas9 | negative selection | 7951848 | 150295253 | 150295276 | 7 | + | 27260156 | NCIH1373 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.47906540844984 | [1755] | [1665,1169,1030,492] | -5 | hSpCas9 | negative selection | 7951849 | 150293305 | 150293328 | 7 | + | 27260156 | NCIH1373 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.29835114942526275 | [405] | [773,221,279,72] | -3 | hSpCas9 | negative selection | 8016131 | 150295271 | 150295294 | 7 | - | 27260156 | PATU8902 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.578344944868525 | [1119] | [3043,1943,1553,3029] | 6 | hSpCas9 | negative selection | 8073099 | 150295253 | 150295276 | 7 | + | 27260156 | PATU8902 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.8436722375228851 | [1755] | [1029,1750,1054,1733] | -7 | hSpCas9 | negative selection | 8073100 | 150293305 | 150293328 | 7 | + | 27260156 | PATU8902 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.08750858526046382 | [405] | [682,653,503,255] | -1 | hSpCas9 | negative selection | 8137382 | 150295271 | 150295294 | 7 | - | 27260156 | PANC1 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.3600363579979253 | [1119] | [1307,1353,1193,1105] | 6 | hSpCas9 | negative selection | 8194350 | 150295253 | 150295276 | 7 | + | 27260156 | PANC1 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.3748697740808751 | [1755] | [1035,1601,1108,1004] | -5 | hSpCas9 | negative selection | 8194351 | 150293305 | 150293328 | 7 | + | 27260156 | PANC1 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.06813965774568467 | [405] | [333,395,357,261] | -1 | hSpCas9 | negative selection | 8258633 | 150295271 | 150295294 | 7 | - | 27260156 | PANC0813 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.5488482262510197 | [1119] | [1889,2031,2057,1723] | 8 | hSpCas9 | negative selection | 8315601 | 150295253 | 150295276 | 7 | + | 27260156 | PANC0813 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.2619355592017536 | [1755] | [2038,1852,1442,1578] | -4 | hSpCas9 | negative selection | 8315602 | 150293305 | 150293328 | 7 | + | 27260156 | PANC0813 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.3904643709360913 | [405] | [274,438,257,467] | -6 | hSpCas9 | negative selection | 8379884 | 150295271 | 150295294 | 7 | - | 27260156 | RDES | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.38003110668748286 | [1119] | [1451,1680,1666,1938] | 6 | hSpCas9 | negative selection | 8436852 | 150295253 | 150295276 | 7 | + | 27260156 | RDES | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.41025970634141196 | [1755] | [1394,1401,1686,1601] | -6 | hSpCas9 | negative selection | 8436853 | 150293305 | 150293328 | 7 | + | 27260156 | RDES | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.49498402947435827 | [405] | [342,289,386,290] | -7 | hSpCas9 | negative selection | 8501135 | 150295271 | 150295294 | 7 | - | 27260156 | PC3 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.0008223081581146818 | [1119] | [663,967,2144,1199] | 0 | hSpCas9 | negative selection | 8558103 | 150295253 | 150295276 | 7 | + | 27260156 | PC3 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.1457515750055618 | [1755] | [910,1284,3124,1788] | -3 | hSpCas9 | negative selection | 8558104 | 150293305 | 150293328 | 7 | + | 27260156 | PC3 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.08261064135490367 | [405] | [294,280,705,568] | 1 | hSpCas9 | negative selection | 8622386 | 150295271 | 150295294 | 7 | - | 27260156 | PATU8988T | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.242515231850845 | [1119] | [1535,1103,1195,1268] | 4 | hSpCas9 | negative selection | 8679354 | 150295253 | 150295276 | 7 | + | 27260156 | PATU8988T | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.3594361444531389 | [1755] | [1417,1318,1330,1212] | -5 | hSpCas9 | negative selection | 8679355 | 150293305 | 150293328 | 7 | + | 27260156 | PATU8988T | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | 0.016986672163688488 | [405] | [317,431,339,510] | 0 | hSpCas9 | negative selection | 8743637 | 150295271 | 150295294 | 7 | - | 27260156 | T47D | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.17606531825890204 | [1119] | [1523,1280,1420,1694] | 4 | hSpCas9 | negative selection | 8800605 | 150295253 | 150295276 | 7 | + | 27260156 | T47D | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.14725925524479422 | [1755] | [1863,2023,1581,1908] | -3 | hSpCas9 | negative selection | 8800606 | 150293305 | 150293328 | 7 | + | 27260156 | T47D | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.06664113938752195 | [405] | [545,444,359,457] | -1 | hSpCas9 | negative selection | 8864888 | 150295271 | 150295294 | 7 | - | 27260156 | SU8686 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.4346553116326126 | [1119] | [1353,1273,1585,1889] | 7 | hSpCas9 | negative selection | 8921856 | 150295253 | 150295276 | 7 | + | 27260156 | SU8686 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.1720379830741856 | [1755] | [1361,1404,1767,1705] | -3 | hSpCas9 | negative selection | 8921857 | 150293305 | 150293328 | 7 | + | 27260156 | SU8686 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.2825041522729246 | [405] | [355,260,367,345] | -5 | hSpCas9 | negative selection | 8986139 | 150295271 | 150295294 | 7 | - | 27260156 | SKES1 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.24492640295977308 | [1119] | [1537,1449,1177,1179] | 5 | hSpCas9 | negative selection | 9043107 | 150295253 | 150295276 | 7 | + | 27260156 | SKES1 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.4054240378313878 | [1755] | [1777,1504,1098,1018] | -7 | hSpCas9 | negative selection | 9043108 | 150293305 | 150293328 | 7 | + | 27260156 | SKES1 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.24688426821185608 | [405] | [461,350,392,190] | -5 | hSpCas9 | negative selection | 9107390 | 150295271 | 150295294 | 7 | - | 27260156 | TOV112D | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | -0.026782953625987815 | [1119] | [1022,1511,819,1140] | 0 | hSpCas9 | negative selection | 9164358 | 150295253 | 150295276 | 7 | + | 27260156 | TOV112D | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | 0.03194234341132152 | [1755] | [1767,2140,2279,1101] | 0 | hSpCas9 | negative selection | 9164359 | 150293305 | 150293328 | 7 | + | 27260156 | TOV112D | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.31460242690806195 | [405] | [299,532,277,246] | -6 | hSpCas9 | negative selection | 9228641 | 150295271 | 150295294 | 7 | - | 27260156 | TC71 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.14605960338582857 | [1119] | [1229,1421,1223,1450] | 3 | hSpCas9 | negative selection | 9285609 | 150295253 | 150295276 | 7 | + | 27260156 | TC71 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.1382130279472522 | [1755] | [1534,1716,1675,1931] | -4 | hSpCas9 | negative selection | 9285610 | 150293305 | 150293328 | 7 | + | 27260156 | TC71 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.194835299966201 | [405] | [367,309,385,461] | -5 | hSpCas9 | negative selection | 9349892 | 150295271 | 150295294 | 7 | - | 27260156 | TC32 | viability | TTCGAATCATTTAACGTTCCAGG | ACTR3C | ENSG00000106526 | 0.5455491307425877 | [1119] | [1555,1172,1619,1869] | 8 | hSpCas9 | negative selection | 9406860 | 150295253 | 150295276 | 7 | + | 27260156 | TC32 | viability | TGAACTGCAATGTAGAGTCCTGG | ACTR3C | ENSG00000106526 | -0.46630251031792436 | [1755] | [1166,701,1556,1557] | -7 | hSpCas9 | negative selection | 9406861 | 150293305 | 150293328 | 7 | + | 27260156 | TC32 | viability | TGCTTACCACTGGGATAACATGG | ACTR3C | ENSG00000106526 | -0.6543565638994122 | [405] | [150,145,397,342] | -8 | hSpCas9 | negative selection | 9471143 | 150293357 | 150293380 | 7 | - | 28162770 | P31FUJ | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.45142192767985434 | [467] | [751] | 5 | hSpCas9 | negative selection | 10106542 | 150289494 | 150289517 | 7 | - | 28162770 | P31FUJ | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | 0.6702014691099801 | [222] | [416] | 7 | hSpCas9 | negative selection | 10106543 | 150286469 | 150286492 | 7 | - | 28162770 | P31FUJ | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.1834657384707259 | [292] | [390] | 2 | hSpCas9 | negative selection | 10106544 | 150284815 | 150284838 | 7 | + | 28162770 | P31FUJ | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 0.2800105105509423 | [81] | [116] | 3 | hSpCas9 | negative selection | 10106545 | 150286458 | 150286481 | 7 | + | 28162770 | P31FUJ | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.31754654122544057 | [927] | [1358] | 3 | hSpCas9 | negative selection | 10106546 | 150284824 | 150284847 | 7 | - | 28162770 | P31FUJ | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.2827865932661154 | [283] | [405] | 3 | hSpCas9 | negative selection | 10106547 | 150284761 | 150284784 | 7 | + | 28162770 | P31FUJ | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -1.4104451190175278 | [327] | [144] | -7 | hSpCas9 | negative selection | 10106548 | 150248987 | 150249010 | 7 | + | 28162770 | P31FUJ | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.17126417704346186 | [98] | [130] | 1 | hSpCas9 | negative selection | 10106549 | 150284742 | 150284765 | 7 | + | 28162770 | P31FUJ | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -0.7588710160819663 | [143] | [99] | -5 | hSpCas9 | negative selection | 10106550 | 150293387 | 150293410 | 7 | + | 28162770 | P31FUJ | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | 0.3767840832755999 | [212] | [324] | 4 | hSpCas9 | negative selection | 10106551 | 150293357 | 150293380 | 7 | - | 28162770 | TF1 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [505] | 1 | hSpCas9 | negative selection | 10275908 | 150289494 | 150289517 | 7 | - | 28162770 | TF1 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [199] | 1 | hSpCas9 | negative selection | 10275909 | 150286469 | 150286492 | 7 | - | 28162770 | TF1 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [137] | 1 | hSpCas9 | negative selection | 10275910 | 150284815 | 150284838 | 7 | + | 28162770 | TF1 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [39] | 1 | hSpCas9 | negative selection | 10275911 | 150286458 | 150286481 | 7 | + | 28162770 | TF1 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [1050] | 1 | hSpCas9 | negative selection | 10275912 | 150284824 | 150284847 | 7 | - | 28162770 | TF1 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [268] | 1 | hSpCas9 | negative selection | 10275913 | 150284761 | 150284784 | 7 | + | 28162770 | TF1 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [299] | 1 | hSpCas9 | negative selection | 10275914 | 150248987 | 150249010 | 7 | + | 28162770 | TF1 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [85] | 1 | hSpCas9 | negative selection | 10275915 | 150284742 | 150284765 | 7 | + | 28162770 | TF1 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [109] | 1 | hSpCas9 | negative selection | 10275916 | 150293387 | 150293410 | 7 | + | 28162770 | TF1 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | NaN | [NaN] | [392] | 1 | hSpCas9 | negative selection | 10275917 | 150293357 | 150293380 | 7 | - | 28162770 | SKM1 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.3350992630627232 | [112] | [251] | 3 | hSpCas9 | negative selection | 10445274 | 150289494 | 150289517 | 7 | - | 28162770 | SKM1 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -0.5794313947479272 | [70] | [83] | -4 | hSpCas9 | negative selection | 10445275 | 150286469 | 150286492 | 7 | - | 28162770 | SKM1 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.10760897408659664 | [104] | [199] | 1 | hSpCas9 | negative selection | 10445276 | 150284815 | 150284838 | 7 | + | 28162770 | SKM1 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 1.4003907233144426 | [20] | [97] | 9 | hSpCas9 | negative selection | 10445277 | 150286458 | 150286481 | 7 | + | 28162770 | SKM1 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.8070159827770862 | [257] | [797] | 7 | hSpCas9 | negative selection | 10445278 | 150284824 | 150284847 | 7 | - | 28162770 | SKM1 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.6079861427228097 | [71] | [193] | 6 | hSpCas9 | negative selection | 10445279 | 150284761 | 150284784 | 7 | + | 28162770 | SKM1 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -0.16303861585707244 | [56] | [89] | -1 | hSpCas9 | negative selection | 10445280 | 150248987 | 150249010 | 7 | + | 28162770 | SKM1 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | -0.1781455082472807 | [31] | [49] | -1 | hSpCas9 | negative selection | 10445281 | 150284742 | 150284765 | 7 | + | 28162770 | SKM1 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -1.167137184070693 | [46] | [36] | -7 | hSpCas9 | negative selection | 10445282 | 150293387 | 150293410 | 7 | + | 28162770 | SKM1 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.11418244951531571 | [59] | [97] | -1 | hSpCas9 | negative selection | 10445283 | 150293357 | 150293380 | 7 | - | 28162770 | SKM1 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.3350992630627232 | [112] | [251] | 3 | hSpCas9 | negative selection | 10614640 | 150289494 | 150289517 | 7 | - | 28162770 | SKM1 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -0.5794313947479272 | [70] | [83] | -4 | hSpCas9 | negative selection | 10614641 | 150286469 | 150286492 | 7 | - | 28162770 | SKM1 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.10760897408659664 | [104] | [199] | 1 | hSpCas9 | negative selection | 10614642 | 150284815 | 150284838 | 7 | + | 28162770 | SKM1 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 1.4003907233144426 | [20] | [97] | 9 | hSpCas9 | negative selection | 10614643 | 150286458 | 150286481 | 7 | + | 28162770 | SKM1 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.8070159827770862 | [257] | [797] | 7 | hSpCas9 | negative selection | 10614644 | 150284824 | 150284847 | 7 | - | 28162770 | SKM1 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.6079861427228097 | [71] | [193] | 6 | hSpCas9 | negative selection | 10614645 | 150284761 | 150284784 | 7 | + | 28162770 | SKM1 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -0.16303861585707244 | [56] | [89] | -1 | hSpCas9 | negative selection | 10614646 | 150248987 | 150249010 | 7 | + | 28162770 | SKM1 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | -0.1781455082472807 | [31] | [49] | -1 | hSpCas9 | negative selection | 10614647 | 150284742 | 150284765 | 7 | + | 28162770 | SKM1 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -1.167137184070693 | [46] | [36] | -7 | hSpCas9 | negative selection | 10614648 | 150293387 | 150293410 | 7 | + | 28162770 | SKM1 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.11418244951531571 | [59] | [97] | -1 | hSpCas9 | negative selection | 10614649 | 150293357 | 150293380 | 7 | - | 28162770 | PL21 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.01348497438930707 | [411] | [180] | 0 | hSpCas9 | negative selection | 10784006 | 150289494 | 150289517 | 7 | - | 28162770 | PL21 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | 1.2744869559494014 | [207] | [218] | 9 | hSpCas9 | negative selection | 10784007 | 150286469 | 150286492 | 7 | - | 28162770 | PL21 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.7269390896523378 | [328] | [236] | 6 | hSpCas9 | negative selection | 10784008 | 150284815 | 150284838 | 7 | + | 28162770 | PL21 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | -0.8731093675413184 | [100] | [23] | -5 | hSpCas9 | negative selection | 10784009 | 150286458 | 150286481 | 7 | + | 28162770 | PL21 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.4985321949158932 | [926] | [569] | 4 | hSpCas9 | negative selection | 10784010 | 150284824 | 150284847 | 7 | - | 28162770 | PL21 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 1.0281161471630098 | [257] | [228] | 8 | hSpCas9 | negative selection | 10784011 | 150284761 | 150284784 | 7 | + | 28162770 | PL21 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -1.356589205502892 | [252] | [42] | -7 | hSpCas9 | negative selection | 10784012 | 150248987 | 150249010 | 7 | + | 28162770 | PL21 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | -2.3441809017344903 | [69] | [5] | -8 | hSpCas9 | negative selection | 10784013 | 150284742 | 150284765 | 7 | + | 28162770 | PL21 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -2.4754254350127427 | [114] | [8] | -9 | hSpCas9 | negative selection | 10784014 | 150293387 | 150293410 | 7 | + | 28162770 | PL21 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | 0.9276801958662576 | [214] | [177] | 7 | hSpCas9 | negative selection | 10784015 | 150293357 | 150293380 | 7 | - | 28162770 | P31FUJ | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.45142192767985434 | [467] | [751] | 5 | hSpCas9 | negative selection | 10953372 | 150289494 | 150289517 | 7 | - | 28162770 | P31FUJ | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | 0.6702014691099801 | [222] | [416] | 7 | hSpCas9 | negative selection | 10953373 | 150286469 | 150286492 | 7 | - | 28162770 | P31FUJ | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.1834657384707259 | [292] | [390] | 2 | hSpCas9 | negative selection | 10953374 | 150284815 | 150284838 | 7 | + | 28162770 | P31FUJ | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 0.2800105105509423 | [81] | [116] | 3 | hSpCas9 | negative selection | 10953375 | 150286458 | 150286481 | 7 | + | 28162770 | P31FUJ | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.31754654122544057 | [927] | [1358] | 3 | hSpCas9 | negative selection | 10953376 | 150284824 | 150284847 | 7 | - | 28162770 | P31FUJ | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.2827865932661154 | [283] | [405] | 3 | hSpCas9 | negative selection | 10953377 | 150284761 | 150284784 | 7 | + | 28162770 | P31FUJ | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -1.4104451190175278 | [327] | [144] | -7 | hSpCas9 | negative selection | 10953378 | 150248987 | 150249010 | 7 | + | 28162770 | P31FUJ | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.17126417704346186 | [98] | [130] | 1 | hSpCas9 | negative selection | 10953379 | 150284742 | 150284765 | 7 | + | 28162770 | P31FUJ | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -0.7588710160819663 | [143] | [99] | -5 | hSpCas9 | negative selection | 10953380 | 150293387 | 150293410 | 7 | + | 28162770 | P31FUJ | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | 0.3767840832755999 | [212] | [324] | 4 | hSpCas9 | negative selection | 10953381 | 150293357 | 150293380 | 7 | - | 28162770 | OCIAML5 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.5101789792108535 | [246] | [634] | 4 | hSpCas9 | negative selection | 11122738 | 150289494 | 150289517 | 7 | - | 28162770 | OCIAML5 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -0.32850461480698395 | [159] | [229] | -2 | hSpCas9 | negative selection | 11122739 | 150286469 | 150286492 | 7 | - | 28162770 | OCIAML5 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.9258556975250671 | [190] | [654] | 7 | hSpCas9 | negative selection | 11122740 | 150284815 | 150284838 | 7 | + | 28162770 | OCIAML5 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | -0.9482818861233003 | [61] | [57] | -5 | hSpCas9 | negative selection | 11122741 | 150286458 | 150286481 | 7 | + | 28162770 | OCIAML5 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 1.1766058190186661 | [410] | [1676] | 8 | hSpCas9 | negative selection | 11122742 | 150284824 | 150284847 | 7 | - | 28162770 | OCIAML5 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.47832310277156154 | [135] | [341] | 4 | hSpCas9 | negative selection | 11122743 | 150284761 | 150284784 | 7 | + | 28162770 | OCIAML5 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -1.2271060022109217 | [165] | [127] | -6 | hSpCas9 | negative selection | 11122744 | 150248987 | 150249010 | 7 | + | 28162770 | OCIAML5 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.5238003311341689 | [83] | [217] | 4 | hSpCas9 | negative selection | 11122745 | 150284742 | 150284765 | 7 | + | 28162770 | OCIAML5 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -0.607332981773147 | [118] | [140] | -4 | hSpCas9 | negative selection | 11122746 | 150293387 | 150293410 | 7 | + | 28162770 | OCIAML5 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | 0.18640757695063875 | [147] | [303] | 1 | hSpCas9 | negative selection | 11122747 | 150293357 | 150293380 | 7 | - | 28162770 | EOL1 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.3544257621602793 | [676] | [455] | 3 | hSpCas9 | negative selection | 11292104 | 150289494 | 150289517 | 7 | - | 28162770 | EOL1 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -1.429089183044166 | [275] | [53] | -7 | hSpCas9 | negative selection | 11292105 | 150286469 | 150286492 | 7 | - | 28162770 | EOL1 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.02408344512144911 | [671] | [359] | 0 | hSpCas9 | negative selection | 11292106 | 150284815 | 150284838 | 7 | + | 28162770 | EOL1 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 0.37300827238682877 | [191] | [130] | 3 | hSpCas9 | negative selection | 11292107 | 150286458 | 150286481 | 7 | + | 28162770 | EOL1 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.3945190234959104 | [1648] | [1141] | 3 | hSpCas9 | negative selection | 11292108 | 150284824 | 150284847 | 7 | - | 28162770 | EOL1 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.10615457806048223 | [491] | [278] | 1 | hSpCas9 | negative selection | 11292109 | 150284761 | 150284784 | 7 | + | 28162770 | EOL1 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -1.6756814858039322 | [284] | [46] | -8 | hSpCas9 | negative selection | 11292110 | 150248987 | 150249010 | 7 | + | 28162770 | EOL1 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.7630843488764183 | [84] | [75] | 6 | hSpCas9 | negative selection | 11292111 | 150284742 | 150284765 | 7 | + | 28162770 | EOL1 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -2.343224553269922 | [182] | [18] | -8 | hSpCas9 | negative selection | 11292112 | 150293387 | 150293410 | 7 | + | 28162770 | EOL1 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | 0.4379889749103728 | [254] | [181] | 4 | hSpCas9 | negative selection | 11292113 | 150293357 | 150293380 | 7 | - | 28162770 | MOLM13 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 1.180087070561843 | [563] | [923] | 8 | hSpCas9 | negative selection | 11461470 | 150289494 | 150289517 | 7 | - | 28162770 | MOLM13 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -1.4698952220097237 | [294] | [76] | -6 | hSpCas9 | negative selection | 11461471 | 150286469 | 150286492 | 7 | - | 28162770 | MOLM13 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.7852509497677294 | [442] | [551] | 6 | hSpCas9 | negative selection | 11461472 | 150284815 | 150284838 | 7 | + | 28162770 | MOLM13 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 1.3546787710965877 | [158] | [293] | 9 | hSpCas9 | negative selection | 11461473 | 150286458 | 150286481 | 7 | + | 28162770 | MOLM13 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.48406067221572435 | [1241] | [1255] | 3 | hSpCas9 | negative selection | 11461474 | 150284824 | 150284847 | 7 | - | 28162770 | MOLM13 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 1.2418602175692435 | [330] | [565] | 8 | hSpCas9 | negative selection | 11461475 | 150284761 | 150284784 | 7 | + | 28162770 | MOLM13 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -0.6984690048775413 | [302] | [134] | -4 | hSpCas9 | negative selection | 11461476 | 150248987 | 150249010 | 7 | + | 28162770 | MOLM13 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 1.0414471189934857 | [126] | [188] | 7 | hSpCas9 | negative selection | 11461477 | 150284742 | 150284765 | 7 | + | 28162770 | MOLM13 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -4.169540539070713 | [223] | [8] | -9 | hSpCas9 | negative selection | 11461478 | 150293387 | 150293410 | 7 | + | 28162770 | MOLM13 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.1601418410684632 | [254] | [164] | -1 | hSpCas9 | negative selection | 11461479 | 150293357 | 150293380 | 7 | - | 28162770 | HEL | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.8213996805070516 | [621] | [703] | 7 | hSpCas9 | negative selection | 11630836 | 150289494 | 150289517 | 7 | - | 28162770 | HEL | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -1.074252062404583 | [262] | [79] | -6 | hSpCas9 | negative selection | 11630837 | 150286469 | 150286492 | 7 | - | 28162770 | HEL | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 0.5704246271844668 | [449] | [427] | 5 | hSpCas9 | negative selection | 11630838 | 150284815 | 150284838 | 7 | + | 28162770 | HEL | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 0.774528704555898 | [114] | [125] | 6 | hSpCas9 | negative selection | 11630839 | 150286458 | 150286481 | 7 | + | 28162770 | HEL | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.8089008996022482 | [1236] | [1387] | 7 | hSpCas9 | negative selection | 11630840 | 150284824 | 150284847 | 7 | - | 28162770 | HEL | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.8263120044462766 | [338] | [384] | 7 | hSpCas9 | negative selection | 11630841 | 150284761 | 150284784 | 7 | + | 28162770 | HEL | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -0.5612750600212366 | [363] | [157] | -4 | hSpCas9 | negative selection | 11630842 | 150248987 | 150249010 | 7 | + | 28162770 | HEL | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.046094526231565514 | [123] | [81] | 0 | hSpCas9 | negative selection | 11630843 | 150284742 | 150284765 | 7 | + | 28162770 | HEL | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -0.9825814063369401 | [144] | [46] | -6 | hSpCas9 | negative selection | 11630844 | 150293387 | 150293410 | 7 | + | 28162770 | HEL | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | 1.0482535571606943 | [227] | [301] | 8 | hSpCas9 | negative selection | 11630845 | 150293357 | 150293380 | 7 | - | 28162770 | MV411 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.21954354464711345 | [469] | [460] | 2 | hSpCas9 | negative selection | 11800202 | 150289494 | 150289517 | 7 | - | 28162770 | MV411 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -0.23383364689615516 | [207] | [148] | -2 | hSpCas9 | negative selection | 11800203 | 150286469 | 150286492 | 7 | - | 28162770 | MV411 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 1.0572734623441344 | [331] | [581] | 8 | hSpCas9 | negative selection | 11800204 | 150284815 | 150284838 | 7 | + | 28162770 | MV411 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 0.3121432401705907 | [108] | [113] | 2 | hSpCas9 | negative selection | 11800205 | 150286458 | 150286481 | 7 | + | 28162770 | MV411 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.5183207999482478 | [885] | [1068] | 4 | hSpCas9 | negative selection | 11800206 | 150284824 | 150284847 | 7 | - | 28162770 | MV411 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.7328643779530171 | [204] | [286] | 6 | hSpCas9 | negative selection | 11800207 | 150284761 | 150284784 | 7 | + | 28162770 | MV411 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -1.337524949938381 | [236] | [78] | -7 | hSpCas9 | negative selection | 11800208 | 150248987 | 150249010 | 7 | + | 28162770 | MV411 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | -0.3791040536897803 | [87] | [56] | -3 | hSpCas9 | negative selection | 11800209 | 150284742 | 150284765 | 7 | + | 28162770 | MV411 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -0.8080575618089283 | [105] | [50] | -5 | hSpCas9 | negative selection | 11800210 | 150293387 | 150293410 | 7 | + | 28162770 | MV411 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.18079944625092767 | [182] | [135] | -1 | hSpCas9 | negative selection | 11800211 | 150293357 | 150293380 | 7 | - | 28162770 | MONOMAC1 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | -0.27897846059572995 | [325] | [307] | -2 | hSpCas9 | negative selection | 11969568 | 150289494 | 150289517 | 7 | - | 28162770 | MONOMAC1 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -0.48243906592180197 | [116] | [95] | -4 | hSpCas9 | negative selection | 11969569 | 150286469 | 150286492 | 7 | - | 28162770 | MONOMAC1 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | -0.43275064689383547 | [271] | [230] | -4 | hSpCas9 | negative selection | 11969570 | 150284815 | 150284838 | 7 | + | 28162770 | MONOMAC1 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 0.018691843995883417 | [61] | [71] | 0 | hSpCas9 | negative selection | 11969571 | 150286458 | 150286481 | 7 | + | 28162770 | MONOMAC1 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.23158362449221492 | [554] | [746] | 2 | hSpCas9 | negative selection | 11969572 | 150284824 | 150284847 | 7 | - | 28162770 | MONOMAC1 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | -0.2563340307433259 | [148] | [142] | -2 | hSpCas9 | negative selection | 11969573 | 150284761 | 150284784 | 7 | + | 28162770 | MONOMAC1 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -1.3501161770639427 | [148] | [66] | -7 | hSpCas9 | negative selection | 11969574 | 150248987 | 150249010 | 7 | + | 28162770 | MONOMAC1 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | -0.5111454374876168 | [91] | [73] | -4 | hSpCas9 | negative selection | 11969575 | 150284742 | 150284765 | 7 | + | 28162770 | MONOMAC1 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | 0.6036543447170397 | [61] | [107] | 6 | hSpCas9 | negative selection | 11969576 | 150293387 | 150293410 | 7 | + | 28162770 | MONOMAC1 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | 0.22318089132497015 | [138] | [185] | 2 | hSpCas9 | negative selection | 11969577 | 150293357 | 150293380 | 7 | - | 28162770 | OCIAML2 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.19574380109399092 | [88] | [564] | 1 | hSpCas9 | negative selection | 12138934 | 150289494 | 150289517 | 7 | - | 28162770 | OCIAML2 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | 0.20030589858884795 | [37] | [241] | 2 | hSpCas9 | negative selection | 12138935 | 150286469 | 150286492 | 7 | - | 28162770 | OCIAML2 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | 1.0295112424130997 | [53] | [610] | 8 | hSpCas9 | negative selection | 12138936 | 150284815 | 150284838 | 7 | + | 28162770 | OCIAML2 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 0.9582134735617129 | [12] | [139] | 8 | hSpCas9 | negative selection | 12138937 | 150286458 | 150286481 | 7 | + | 28162770 | OCIAML2 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 1.0520227736836478 | [137] | [1585] | 8 | hSpCas9 | negative selection | 12138938 | 150284824 | 150284847 | 7 | - | 28162770 | OCIAML2 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 0.8209246206016823 | [47] | [469] | 7 | hSpCas9 | negative selection | 12138939 | 150284761 | 150284784 | 7 | + | 28162770 | OCIAML2 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -1.1890594679709399 | [57] | [140] | -7 | hSpCas9 | negative selection | 12138940 | 150248987 | 150249010 | 7 | + | 28162770 | OCIAML2 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.9888017933951362 | [14] | [164] | 8 | hSpCas9 | negative selection | 12138941 | 150284742 | 150284765 | 7 | + | 28162770 | OCIAML2 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -1.4957208062049916 | [28] | [56] | -7 | hSpCas9 | negative selection | 12138942 | 150293387 | 150293410 | 7 | + | 28162770 | OCIAML2 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.19932780342476697 | [28] | [139] | -2 | hSpCas9 | negative selection | 12138943 | 150293357 | 150293380 | 7 | - | 28162770 | OCIAML3 | viability | TGGGTGAACGTACATTAACGGGG | ACTR3C | ENSG00000106526 | 0.8796981092952518 | [127] | [710] | 7 | hSpCas9 | negative selection | 12308300 | 150289494 | 150289517 | 7 | - | 28162770 | OCIAML3 | viability | GCTGCTAAGGGAGAGGGAGGTGG | ACTR3C | ENSG00000106526 | -0.9590044571034115 | [84] | [131] | -6 | hSpCas9 | negative selection | 12308301 | 150286469 | 150286492 | 7 | - | 28162770 | OCIAML3 | viability | ATGATGTGGATCCCCAGAAGTGG | ACTR3C | ENSG00000106526 | -0.34066663069421343 | [111] | [266] | -3 | hSpCas9 | negative selection | 12308302 | 150284815 | 150284838 | 7 | + | 28162770 | OCIAML3 | viability | AGATGGACTCCATAGAGTCTGGG | ACTR3C | ENSG00000106526 | 1.506793000463329 | [18] | [162] | 9 | hSpCas9 | negative selection | 12308303 | 150286458 | 150286481 | 7 | + | 28162770 | OCIAML3 | viability | TACTGTTTGATCCACTTCTGGGG | ACTR3C | ENSG00000106526 | 0.319736626325418 | [223] | [843] | 3 | hSpCas9 | negative selection | 12308304 | 150284824 | 150284847 | 7 | - | 28162770 | OCIAML3 | viability | GTTTGCCAACCCAGACTCTATGG | ACTR3C | ENSG00000106526 | 1.5575388318032946 | [78] | [701] | 9 | hSpCas9 | negative selection | 12308305 | 150284761 | 150284784 | 7 | + | 28162770 | OCIAML3 | viability | GCGGACGCCGCACATCGATGGGG | ACTR3C | ENSG00000106526 | -1.0634929236253832 | [71] | [103] | -6 | hSpCas9 | negative selection | 12308306 | 150248987 | 150249010 | 7 | + | 28162770 | OCIAML3 | viability | CAATGAAATGGAGGTGACAGAGG | ACTR3C | ENSG00000106526 | 0.6447792192629533 | [24] | [117] | 6 | hSpCas9 | negative selection | 12308307 | 150284742 | 150284765 | 7 | + | 28162770 | OCIAML3 | viability | GCAGCTCATACCTTATACAGCGG | ACTR3C | ENSG00000106526 | -0.5065447990738239 | [31] | [67] | -4 | hSpCas9 | negative selection | 12308308 | 150293387 | 150293410 | 7 | + | 28162770 | OCIAML3 | viability | AGATGTCCAAGATGCCGCCAAGG | ACTR3C | ENSG00000106526 | -0.5224543792991292 | [58] | [123] | -4 | hSpCas9 | negative selection | 12308309 |