Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:79913
• Symbol:ACTR5
• Description:actin related protein 5

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTR5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
38748590	38748613	20	+	26472758	Jiyoye	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.2730676226483914	[132]	[82]	-2	hSpCas9	negative selection	2233
38765508	38765531	20	-	26472758	Jiyoye	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	-0.7556392307732491	[252]	[112]	-5	hSpCas9	negative selection	2234
38748732	38748755	20	+	26472758	Jiyoye	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-1.3033180012991419	[35]	[10]	-7	hSpCas9	negative selection	2235
38748743	38748766	20	-	26472758	Jiyoye	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	0.9690542691139883	[20]	[30]	6	hSpCas9	negative selection	2236
38752188	38752211	20	-	26472758	Jiyoye	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-1.3583593648571035	[33]	[9]	-7	hSpCas9	negative selection	2237
38752266	38752289	20	+	26472758	Jiyoye	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	1.1865762419924761	[66]	[114]	7	hSpCas9	negative selection	2238
38755071	38755094	20	+	26472758	Jiyoye	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.0681626280407847	[113]	[81]	0	hSpCas9	negative selection	2239
38755946	38755969	20	+	26472758	Jiyoye	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.23527261387604304	[255]	[163]	-2	hSpCas9	negative selection	2240
38755994	38756017	20	+	26472758	Jiyoye	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-0.0078621177729703	[15]	[11]	0	hSpCas9	negative selection	2241
38765465	38765488	20	-	26472758	Jiyoye	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	2.9921378822270293	[0]	[5]	9	hSpCas9	negative selection	2242
38748590	38748613	20	+	26472758	KBM7	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.7851305609486318	[612,375]	[145,119]	-6	hSpCas9	negative selection	193351
38765508	38765531	20	-	26472758	KBM7	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	-0.8092423882354038	[622,465]	[84,197]	-6	hSpCas9	negative selection	193352
38748732	38748755	20	+	26472758	KBM7	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-2.764906667444377	[174,195]	[22,3]	-9	hSpCas9	negative selection	193353
38748743	38748766	20	-	26472758	KBM7	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-1.5297130421831273	[145,76]	[4,28]	-8	hSpCas9	negative selection	193354
38752188	38752211	20	-	26472758	KBM7	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-3.2673203047143886	[222,146]	[10,6]	-9	hSpCas9	negative selection	193355
38752266	38752289	20	+	26472758	KBM7	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-1.8889026442094947	[660,528]	[92,58]	-8	hSpCas9	negative selection	193356
38755071	38755094	20	+	26472758	KBM7	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.08836088914476882	[457,411]	[120,255]	-1	hSpCas9	negative selection	193357
38755946	38755969	20	+	26472758	KBM7	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.04071413969062747	[464,463]	[291,142]	0	hSpCas9	negative selection	193358
38755994	38756017	20	+	26472758	KBM7	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-1.9901873986328869	[85,51]	[7,7]	-8	hSpCas9	negative selection	193359
38765465	38765488	20	-	26472758	KBM7	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	1.2524807812098349	[6,10]	[12,7]	9	hSpCas9	negative selection	193360
38748590	38748613	20	+	26472758	Raji	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	0.6273905942539859	[211]	[75]	6	hSpCas9	negative selection	384469
38765508	38765531	20	-	26472758	Raji	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.47775198531871504	[327]	[105]	4	hSpCas9	negative selection	384470
38748732	38748755	20	+	26472758	Raji	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-1.039457852955672	[61]	[6]	-6	hSpCas9	negative selection	384471
38748743	38748766	20	-	26472758	Raji	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-0.09425032579605097	[91]	[19]	-1	hSpCas9	negative selection	384472
38752188	38752211	20	-	26472758	Raji	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	0.785455440486237	[49]	[19]	7	hSpCas9	negative selection	384473
38752266	38752289	20	+	26472758	Raji	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.6443574114730051	[228]	[33]	-5	hSpCas9	negative selection	384474
38755071	38755094	20	+	26472758	Raji	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.4579501585986242	[218]	[36]	-4	hSpCas9	negative selection	384475
38755946	38755969	20	+	26472758	Raji	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.7786118359235692	[376]	[50]	-5	hSpCas9	negative selection	384476
38755994	38756017	20	+	26472758	Raji	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-2.021899481571367	[34]	[1]	-8	hSpCas9	negative selection	384477
38765465	38765488	20	-	26472758	Raji	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	-2.352048083263698	[21]	[0]	-9	hSpCas9	negative selection	384478
38748590	38748613	20	+	26472758	K562	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	0.7422486366616288	[363]	[513]	6	hSpCas9	negative selection	575587
38765508	38765531	20	-	26472758	K562	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.08949815083910262	[549]	[493]	0	hSpCas9	negative selection	575588
38748732	38748755	20	+	26472758	K562	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-2.916573149005858	[160]	[17]	-8	hSpCas9	negative selection	575589
38748743	38748766	20	-	26472758	K562	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	0.8341347583582377	[100]	[151]	7	hSpCas9	negative selection	575590
38752188	38752211	20	-	26472758	K562	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-5.4280066143050485	[101]	[1]	-9	hSpCas9	negative selection	575591
38752266	38752289	20	+	26472758	K562	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	0.5074531335002407	[374]	[449]	4	hSpCas9	negative selection	575592
38755071	38755094	20	+	26472758	K562	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	1.3710748691793895	[266]	[582]	9	hSpCas9	negative selection	575593
38755946	38755969	20	+	26472758	K562	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	0.40215819066064146	[501]	[559]	3	hSpCas9	negative selection	575594
38755994	38756017	20	+	26472758	K562	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-5.399437462108277	[49]	[0]	-9	hSpCas9	negative selection	575595
38765465	38765488	20	-	26472758	K562	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	3.492346241110032	[1]	[18]	9	hSpCas9	negative selection	575596
38748570	38748593	20	+	26627737	DLD1	viability	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	-0.5473549487676743	[1753]	[359,348,409]	-5	hSpCas9	negative selection	814473
38750093	38750116	20	+	26627737	DLD1	viability	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.0401611150231604	[213]	[42,20,32]	-7	hSpCas9	negative selection	814474
38752198	38752221	20	+	26627737	DLD1	viability	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.31504737139789496	[1482]	[419,353,346]	-3	hSpCas9	negative selection	814475
38755098	38755121	20	+	26627737	DLD1	viability	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.3339497684543081	[188]	[113,87,28]	3	hSpCas9	negative selection	814476
38755859	38755882	20	+	26627737	DLD1	viability	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-2.2997076272879133	[115]	[10,3,6]	-9	hSpCas9	negative selection	814477
38766322	38766345	20	+	26627737	DLD1	viability	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.5678413376745262	[307]	[10,95,85]	-5	hSpCas9	negative selection	814478
38748570	38748593	20	+	26627737	GBM cells	viability after 5 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.06606286038414533	[577]	[398,249]	1	hSpCas9	negative selection	896788
38750093	38750116	20	+	26627737	GBM cells	viability after 5 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.8437540786447038	[168]	[35,64]	-8	hSpCas9	negative selection	896789
38752198	38752221	20	+	26627737	GBM cells	viability after 5 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	0.011487823224697546	[726]	[379,405]	0	hSpCas9	negative selection	896790
38755098	38755121	20	+	26627737	GBM cells	viability after 5 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-0.7983515954602629	[226]	[74,64]	-8	hSpCas9	negative selection	896791
38755859	38755882	20	+	26627737	GBM cells	viability after 5 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	0.5439973680444123	[93]	[65,80]	7	hSpCas9	negative selection	896792
38766322	38766345	20	+	26627737	GBM cells	viability after 5 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	0.18213844044256386	[271]	[119,210]	3	hSpCas9	negative selection	896793
38748570	38748593	20	+	26627737	GBM cells	viability after 13 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.009413152162615734	[577]	[329,303]	0	hSpCas9	negative selection	979103
38750093	38750116	20	+	26627737	GBM cells	viability after 13 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.9001748866191059	[168]	[36,58]	-8	hSpCas9	negative selection	979104
38752198	38752221	20	+	26627737	GBM cells	viability after 13 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	0.333671058732391	[726]	[629,388]	4	hSpCas9	negative selection	979105
38755098	38755121	20	+	26627737	GBM cells	viability after 13 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-1.2027801095942643	[226]	[31,70]	-8	hSpCas9	negative selection	979106
38755859	38755882	20	+	26627737	GBM cells	viability after 13 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	0.42166959904628964	[93]	[80,57]	5	hSpCas9	negative selection	979107
38766322	38766345	20	+	26627737	GBM cells	viability after 13 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.33327335069157715	[271]	[120,113]	-4	hSpCas9	negative selection	979108
38748570	38748593	20	+	26627737	GBM cells	viability after 21 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.0953332283857502	[577]	[347,323]	1	hSpCas9	negative selection	1061418
38750093	38750116	20	+	26627737	GBM cells	viability after 21 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.0528594686320145	[168]	[49,38]	-7	hSpCas9	negative selection	1061419
38752198	38752221	20	+	26627737	GBM cells	viability after 21 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.30199801770775014	[726]	[299,338]	-3	hSpCas9	negative selection	1061420
38755098	38755121	20	+	26627737	GBM cells	viability after 21 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-0.3114638111617412	[226]	[113,85]	-3	hSpCas9	negative selection	1061421
38755859	38755882	20	+	26627737	GBM cells	viability after 21 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-0.7103677392652554	[93]	[37,24]	-6	hSpCas9	negative selection	1061422
38766322	38766345	20	+	26627737	GBM cells	viability after 21 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.018393468604152377	[271]	[159,132]	0	hSpCas9	negative selection	1061423
38748570	38748593	20	+	26627737	RPE1	viability after 9 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.15172663244749196	[1559]	[411,710]	1	hSpCas9	negative selection	1143733
38750093	38750116	20	+	26627737	RPE1	viability after 9 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.7456775347974054	[580]	[48,60]	-8	hSpCas9	negative selection	1143734
38752198	38752221	20	+	26627737	RPE1	viability after 9 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.5958756621624681	[2118]	[248,683]	-4	hSpCas9	negative selection	1143735
38755098	38755121	20	+	26627737	RPE1	viability after 9 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.9021092798726864	[392]	[132,354]	6	hSpCas9	negative selection	1143736
38755859	38755882	20	+	26627737	RPE1	viability after 9 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-0.243912472332096	[195]	[53,48]	-2	hSpCas9	negative selection	1143737
38766322	38766345	20	+	26627737	RPE1	viability after 9 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-3.580051958810081	[1810]	[32,65]	-9	hSpCas9	negative selection	1143738
38748570	38748593	20	+	26627737	RPE1	viability after 12 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.21215103365361654	[1559]	[485,484]	1	hSpCas9	negative selection	1226048
38750093	38750116	20	+	26627737	RPE1	viability after 12 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-2.6227756643752937	[580]	[36,12]	-9	hSpCas9	negative selection	1226049
38752198	38752221	20	+	26627737	RPE1	viability after 12 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.8448474675186461	[2118]	[332,299]	-5	hSpCas9	negative selection	1226050
38755098	38755121	20	+	26627737	RPE1	viability after 12 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-0.017876358875693277	[392]	[62,147]	0	hSpCas9	negative selection	1226051
38755859	38755882	20	+	26627737	RPE1	viability after 12 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-0.40908959680877555	[195]	[10,69]	-3	hSpCas9	negative selection	1226052
38766322	38766345	20	+	26627737	RPE1	viability after 12 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-3.2629521419209326	[1810]	[39,61]	-9	hSpCas9	negative selection	1226053
38748570	38748593	20	+	26627737	RPE1	viability after 15 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.5962746662520926	[1559]	[658,674]	4	hSpCas9	negative selection	1308363
38750093	38750116	20	+	26627737	RPE1	viability after 15 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-3.209887329154875	[580]	[2,31]	-9	hSpCas9	negative selection	1308364
38752198	38752221	20	+	26627737	RPE1	viability after 15 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-1.2193453422151328	[2118]	[260,253]	-6	hSpCas9	negative selection	1308365
38755098	38755121	20	+	26627737	RPE1	viability after 15 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-0.7791983593617594	[392]	[20,106]	-5	hSpCas9	negative selection	1308366
38755859	38755882	20	+	26627737	RPE1	viability after 15 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-0.5892531121717925	[195]	[16,55]	-4	hSpCas9	negative selection	1308367
38766322	38766345	20	+	26627737	RPE1	viability after 15 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-4.235335211748087	[1810]	[15,37]	-9	hSpCas9	negative selection	1308368
38748570	38748593	20	+	26627737	RPE1	viability after 18 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.39538879992418785	[1559]	[443,670]	2	hSpCas9	negative selection	1390678
38750093	38750116	20	+	26627737	RPE1	viability after 18 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-6.268991444511426	[580]	[2,0]	-9	hSpCas9	negative selection	1390679
38752198	38752221	20	+	26627737	RPE1	viability after 18 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.773238672851381	[2118]	[380,284]	-5	hSpCas9	negative selection	1390680
38755098	38755121	20	+	26627737	RPE1	viability after 18 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-0.24539812257561444	[392]	[73,105]	-1	hSpCas9	negative selection	1390681
38755859	38755882	20	+	26627737	RPE1	viability after 18 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-3.441920306403456	[195]	[0,8]	-9	hSpCas9	negative selection	1390682
38766322	38766345	20	+	26627737	RPE1	viability after 18 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-3.6248871140875707	[1810]	[42,35]	-9	hSpCas9	negative selection	1390683
38748570	38748593	20	+	26627737	HeLa	viability after 8 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.8014618898951703	[729]	[706,587,409]	6	hSpCas9	negative selection	1472993
38750093	38750116	20	+	26627737	HeLa	viability after 8 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	0.11839933943890468	[204]	[151,73,77]	1	hSpCas9	negative selection	1472994
38752198	38752221	20	+	26627737	HeLa	viability after 8 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.0586284254788505	[915]	[561,248,376]	0	hSpCas9	negative selection	1472995
38755098	38755121	20	+	26627737	HeLa	viability after 8 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-1.0513496459441933	[238]	[106,19,36]	-8	hSpCas9	negative selection	1472996
38755859	38755882	20	+	26627737	HeLa	viability after 8 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-0.7184700467443981	[136]	[45,30,33]	-6	hSpCas9	negative selection	1472997
38766322	38766345	20	+	26627737	HeLa	viability after 8 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.43849585434535354	[471]	[250,139,89]	-4	hSpCas9	negative selection	1472998
38748570	38748593	20	+	26627737	HeLa	viability after 12 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.3785161872074386	[729]	[305,439,422]	3	hSpCas9	negative selection	1555308
38750093	38750116	20	+	26627737	HeLa	viability after 12 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.3411156396055506	[204]	[0,36,60]	-8	hSpCas9	negative selection	1555309
38752198	38752221	20	+	26627737	HeLa	viability after 12 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.18653232983297796	[915]	[452,345,200]	-2	hSpCas9	negative selection	1555310
38755098	38755121	20	+	26627737	HeLa	viability after 12 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-0.4271735405999413	[238]	[81,50,89]	-4	hSpCas9	negative selection	1555311
38755859	38755882	20	+	26627737	HeLa	viability after 12 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-1.338001186974377	[136]	[3,37,22]	-8	hSpCas9	negative selection	1555312
38766322	38766345	20	+	26627737	HeLa	viability after 12 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.2929074890763493	[471]	[196,71,218]	-3	hSpCas9	negative selection	1555313
38748570	38748593	20	+	26627737	HeLa	viability after 15 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.6703701977928523	[729]	[573,413,425]	5	hSpCas9	negative selection	1637623
38750093	38750116	20	+	26627737	HeLa	viability after 15 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.425011391540158	[204]	[5,14,75]	-8	hSpCas9	negative selection	1637624
38752198	38752221	20	+	26627737	HeLa	viability after 15 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.3922507684438312	[915]	[294,239,319]	-3	hSpCas9	negative selection	1637625
38755098	38755121	20	+	26627737	HeLa	viability after 15 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.30325748958926	[238]	[135,175,41]	2	hSpCas9	negative selection	1637626
38755859	38755882	20	+	26627737	HeLa	viability after 15 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-0.6190377068315649	[136]	[29,42,35]	-5	hSpCas9	negative selection	1637627
38766322	38766345	20	+	26627737	HeLa	viability after 15 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	0.08620937762860947	[471]	[216,151,245]	0	hSpCas9	negative selection	1637628
38748570	38748593	20	+	26627737	HeLa	viability after 18 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.675414745306152	[729]	[384,346,425]	5	hSpCas9	negative selection	1719938
38750093	38750116	20	+	26627737	HeLa	viability after 18 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.4145995330565122	[204]	[3,12,75]	-8	hSpCas9	negative selection	1719939
38752198	38752221	20	+	26627737	HeLa	viability after 18 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.38266709521589637	[915]	[198,201,319]	-3	hSpCas9	negative selection	1719940
38755098	38755121	20	+	26627737	HeLa	viability after 18 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.314104236025127	[238]	[95,141,41]	2	hSpCas9	negative selection	1719941
38755859	38755882	20	+	26627737	HeLa	viability after 18 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-0.6691849955717086	[136]	[18,33,35]	-5	hSpCas9	negative selection	1719942
38766322	38766345	20	+	26627737	HeLa	viability after 18 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	0.1025227495953514	[471]	[153,120,245]	0	hSpCas9	negative selection	1719943
38748570	38748593	20	+	26627737	HCT116	viability after 6 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.6238005452880007	[1221]	[422,225]	3	hSpCas9	negative selection	1802253
38750093	38750116	20	+	26627737	HCT116	viability after 6 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.735290106208905	[308]	[14,36]	-4	hSpCas9	negative selection	1802254
38752198	38752221	20	+	26627737	HCT116	viability after 6 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	0.29662297085156974	[1894]	[236,436]	1	hSpCas9	negative selection	1802255
38755098	38755121	20	+	26627737	HCT116	viability after 6 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	1.3700915909185816	[375]	[204,123]	7	hSpCas9	negative selection	1802256
38755859	38755882	20	+	26627737	HCT116	viability after 6 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-1.1721648666661575	[370]	[70,0]	-6	hSpCas9	negative selection	1802257
38766322	38766345	20	+	26627737	HCT116	viability after 6 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	0.8797621013715496	[437]	[185,93]	5	hSpCas9	negative selection	1802258
38748570	38748593	20	+	26627737	HCT116	viability after 8 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	-0.15271194946551803	[642]	[334,264,355]	-2	hSpCas9	negative selection	1884568
38750093	38750116	20	+	26627737	HCT116	viability after 8 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	0.08010709852973674	[161]	[84,109,87]	1	hSpCas9	negative selection	1884569
38752198	38752221	20	+	26627737	HCT116	viability after 8 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.10469048530244307	[819]	[349,456,451]	-1	hSpCas9	negative selection	1884570
38755098	38755121	20	+	26627737	HCT116	viability after 8 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.13610490934427155	[194]	[132,143,77]	1	hSpCas9	negative selection	1884571
38755859	38755882	20	+	26627737	HCT116	viability after 8 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	1.1448781610992387	[57]	[65,80,64]	8	hSpCas9	negative selection	1884572
38766322	38766345	20	+	26627737	HCT116	viability after 8 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.6698211666427452	[494]	[118,105,286]	-7	hSpCas9	negative selection	1884573
38748570	38748593	20	+	26627737	HCT116	viability after 9 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	-0.04342279034371288	[1221]	[386,260]	0	hSpCas9	negative selection	1966883
38750093	38750116	20	+	26627737	HCT116	viability after 9 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.780969265254474	[308]	[42,8]	-8	hSpCas9	negative selection	1966884
38752198	38752221	20	+	26627737	HCT116	viability after 9 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.019523404972117575	[1894]	[482,511]	0	hSpCas9	negative selection	1966885
38755098	38755121	20	+	26627737	HCT116	viability after 9 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-0.16716351975659216	[375]	[32,133]	-1	hSpCas9	negative selection	1966886
38755859	38755882	20	+	26627737	HCT116	viability after 9 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-1.5211961211935605	[370]	[0,60]	-8	hSpCas9	negative selection	1966887
38766322	38766345	20	+	26627737	HCT116	viability after 9 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	0.7699589866926098	[437]	[242,164]	5	hSpCas9	negative selection	1966888
38748570	38748593	20	+	26627737	HCT116	viability after 12 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.3787326531958002	[642]	[538,343,423]	4	hSpCas9	negative selection	2049198
38750093	38750116	20	+	26627737	HCT116	viability after 12 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.510536612585838	[161]	[56,37,83]	-5	hSpCas9	negative selection	2049199
38752198	38752221	20	+	26627737	HCT116	viability after 12 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.05382513823052326	[819]	[345,640,269]	0	hSpCas9	negative selection	2049200
38755098	38755121	20	+	26627737	HCT116	viability after 12 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.33042884820064916	[194]	[169,130,81]	3	hSpCas9	negative selection	2049201
38755859	38755882	20	+	26627737	HCT116	viability after 12 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	1.1005958021330446	[57]	[33,112,52]	8	hSpCas9	negative selection	2049202
38766322	38766345	20	+	26627737	HCT116	viability after 12 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-1.086271932920568	[494]	[84,169,116]	-8	hSpCas9	negative selection	2049203
38748570	38748593	20	+	26627737	HCT116	viability after 15 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.3017426339726639	[642]	[488,454,425]	3	hSpCas9	negative selection	2131513
38750093	38750116	20	+	26627737	HCT116	viability after 15 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.2318042534146225	[161]	[54,49,15]	-8	hSpCas9	negative selection	2131514
38752198	38752221	20	+	26627737	HCT116	viability after 15 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.0038439548857618355	[819]	[632,501,295]	0	hSpCas9	negative selection	2131515
38755098	38755121	20	+	26627737	HCT116	viability after 15 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-0.3591992965986506	[194]	[101,98,62]	-4	hSpCas9	negative selection	2131516
38755859	38755882	20	+	26627737	HCT116	viability after 15 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	1.8247740469726017	[57]	[47,139,156]	9	hSpCas9	negative selection	2131517
38766322	38766345	20	+	26627737	HCT116	viability after 15 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.9784277695727905	[494]	[152,144,135]	-7	hSpCas9	negative selection	2131518
38748570	38748593	20	+	26627737	HCT116	viability after 18 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.6517641541138481	[642]	[467,403,603]	5	hSpCas9	negative selection	2213828
38750093	38750116	20	+	26627737	HCT116	viability after 18 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.9464251863839531	[161]	[32,25,64]	-7	hSpCas9	negative selection	2213829
38752198	38752221	20	+	26627737	HCT116	viability after 18 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.49332227534764694	[819]	[262,347,226]	-4	hSpCas9	negative selection	2213830
38755098	38755121	20	+	26627737	HCT116	viability after 18 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.3904586892349144	[194]	[247,52,71]	3	hSpCas9	negative selection	2213831
38755859	38755882	20	+	26627737	HCT116	viability after 18 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	0.9483546560252534	[57]	[39,36,87]	7	hSpCas9	negative selection	2213832
38766322	38766345	20	+	26627737	HCT116	viability after 18 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.7821219289345238	[494]	[215,145,50]	-6	hSpCas9	negative selection	2213833
38748496	38748519	20	-	24336569	HL60	viability	CGGCACGGGCGTCGCGGAACGGG	ACTR5	ENSG00000101442	1.0188864247035725	[589]	[2529]	7	hSpCas9	negative selection	2246493
38748510	38748533	20	-	24336569	HL60	viability	CACTGGGTCCGGTGCGGCACGGG	ACTR5	ENSG00000101442	2.240463994258466	[65]	[659]	9	hSpCas9	negative selection	2246494
38748516	38748539	20	-	24336569	HL60	viability	CTCCAGCACTGGGTCCGGTGCGG	ACTR5	ENSG00000101442	0.7675600007297814	[233]	[842]	6	hSpCas9	negative selection	2246495
38748521	38748544	20	+	24336569	HL60	viability	CCGGACCCAGTGCTGGAGGCCGG	ACTR5	ENSG00000101442	1.0330956636339597	[362]	[1571]	7	hSpCas9	negative selection	2246496
38748526	38748549	20	-	24336569	HL60	viability	CCGGGCCGGCCTCCAGCACTGGG	ACTR5	ENSG00000101442	0.27385016275301277	[298]	[764]	2	hSpCas9	negative selection	2246497
38748536	38748559	20	+	24336569	HL60	viability	GAGGCCGGCCCGGTGGCACACGG	ACTR5	ENSG00000101442	1.3227404674637757	[258]	[1370]	8	hSpCas9	negative selection	2246498
38748544	38748567	20	-	24336569	HL60	viability	GCAGTGGCCCGTGTGCCACCGGG	ACTR5	ENSG00000101442	1.3531100917991992	[462]	[2502]	8	hSpCas9	negative selection	2246499
38748556	38748579	20	+	24336569	HL60	viability	CGGGCCACTGCCGGTACCGCTGG	ACTR5	ENSG00000101442	0.32078724369410416	[254]	[673]	3	hSpCas9	negative selection	2246500
38748562	38748585	20	+	24336569	HL60	viability	ACTGCCGGTACCGCTGGTGCTGG	ACTR5	ENSG00000101442	0.43925821419029787	[198]	[570]	4	hSpCas9	negative selection	2246501
38748569	38748592	20	+	24336569	HL60	viability	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	-0.9621651722565518	[695]	[755]	-7	hSpCas9	negative selection	2246502
38748496	38748519	20	-	24336569	KBM7	viability	CGGCACGGGCGTCGCGGAACGGG	ACTR5	ENSG00000101442	1.0413564163984979	[527]	[2963]	8	hSpCas9	negative selection	2313670
38748510	38748533	20	-	24336569	KBM7	viability	CACTGGGTCCGGTGCGGCACGGG	ACTR5	ENSG00000101442	-0.6471436884310688	[208]	[363]	-5	hSpCas9	negative selection	2313671
38748516	38748539	20	-	24336569	KBM7	viability	CTCCAGCACTGGGTCCGGTGCGG	ACTR5	ENSG00000101442	-1.2479701708567223	[309]	[355]	-7	hSpCas9	negative selection	2313672
38748521	38748544	20	+	24336569	KBM7	viability	CCGGACCCAGTGCTGGAGGCCGG	ACTR5	ENSG00000101442	-0.6798513486119893	[463]	[789]	-5	hSpCas9	negative selection	2313673
38748526	38748549	20	-	24336569	KBM7	viability	CCGGGCCGGCCTCCAGCACTGGG	ACTR5	ENSG00000101442	0.002942015673157994	[250]	[685]	0	hSpCas9	negative selection	2313674
38748536	38748559	20	+	24336569	KBM7	viability	GAGGCCGGCCCGGTGGCACACGG	ACTR5	ENSG00000101442	-0.2022863731023557	[374]	[888]	-2	hSpCas9	negative selection	2313675
38748544	38748567	20	-	24336569	KBM7	viability	GCAGTGGCCCGTGTGCCACCGGG	ACTR5	ENSG00000101442	-0.002322807854175074	[436]	[1189]	0	hSpCas9	negative selection	2313676
38748556	38748579	20	+	24336569	KBM7	viability	CGGGCCACTGCCGGTACCGCTGG	ACTR5	ENSG00000101442	0.6263548383859276	[270]	[1140]	5	hSpCas9	negative selection	2313677
38748562	38748585	20	+	24336569	KBM7	viability	ACTGCCGGTACCGCTGGTGCTGG	ACTR5	ENSG00000101442	0.20525541706473205	[172]	[543]	2	hSpCas9	negative selection	2313678
38748569	38748592	20	+	24336569	KBM7	viability	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	-1.2060389336156345	[416]	[492]	-7	hSpCas9	negative selection	2313679
38764698	38764721	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGCTCTTTCACCCAGGCTGG	ACTR5	ENSG00000101442	-3.4752685797456295	[670,81]	[9,2]	-9	dCas9-VP64	positive selection	2390717
38764698	38764721	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGCTCTTTCACCCAGGCTGG	ACTR5	ENSG00000101442	0.8980088860596516	[158,118]	[140,31]	6	dCas9-VP64	positive selection	2485972
38748652	38748675	20	-	27260157	DLD1	viability	CGCACACCGCGCGGAACTGCAGG	ACTR5	ENSG00000101442	-1.70574793664972	[]	[]	-8	hSpCas9	negative selection	2575338
38748590	38748613	20	+	27260157	DLD1	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-2.00324605550277	[]	[]	-8	hSpCas9	negative selection	2577212
38748516	38748539	20	-	27260157	DLD1	viability	CTCCAGCACTGGGTCCGGTGCGG	ACTR5	ENSG00000101442	-0.313124737045189	[]	[]	-3	hSpCas9	negative selection	2577642
38748641	38748664	20	-	27260157	DLD1	viability	CGGAACTGCAGGCGCGGCTCGGG	ACTR5	ENSG00000101442	-0.912913041727499	[]	[]	-6	hSpCas9	negative selection	2580037
38748562	38748585	20	+	27260157	DLD1	viability	ACTGCCGGTACCGCTGGTGCTGG	ACTR5	ENSG00000101442	-0.99385010373083	[]	[]	-7	hSpCas9	negative selection	2580670
38748736	38748759	20	-	27260157	DLD1	viability	GCATCCAGCGCAGTGGCTCCAGG	ACTR5	ENSG00000101442	-0.505303835988032	[]	[]	-4	hSpCas9	negative selection	2582895
38748514	38748537	20	+	27260157	DLD1	viability	TGCCGCACCGGACCCAGTGCTGG	ACTR5	ENSG00000101442	0.198294075247339	[]	[]	3	hSpCas9	negative selection	2583572
38748496	38748519	20	-	27260157	DLD1	viability	CGGCACGGGCGTCGCGGAACGGG	ACTR5	ENSG00000101442	-0.897990075889752	[]	[]	-6	hSpCas9	negative selection	2585476
38748569	38748592	20	+	27260157	DLD1	viability	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	-1.49543988741282	[]	[]	-8	hSpCas9	negative selection	2587486
38748767	38748790	20	-	27260157	DLD1	viability	ACCGGCACGTTGCGGTCGAAGGG	ACTR5	ENSG00000101442	-0.619904807072776	[]	[]	-5	hSpCas9	negative selection	2604216
38748598	38748621	20	-	27260157	DLD1	viability	ACGCCCAGCCAGCGCGGACTTGG	ACTR5	ENSG00000101442	0.107126223061739	[]	[]	3	hSpCas9	negative selection	2604536
38748846	38748869	20	-	27260157	DLD1	viability	TACTCCGCCCTTCACCTGTGAGG	ACTR5	ENSG00000101442	-1.16189464887479	[]	[]	-7	hSpCas9	negative selection	2606157
38748510	38748533	20	-	27260157	DLD1	viability	CACTGGGTCCGGTGCGGCACGGG	ACTR5	ENSG00000101442	-1.21072364721683	[]	[]	-7	hSpCas9	negative selection	2607261
38748544	38748567	20	-	27260157	DLD1	viability	GCAGTGGCCCGTGTGCCACCGGG	ACTR5	ENSG00000101442	-0.67427287037907	[]	[]	-5	hSpCas9	negative selection	2608673
38750093	38750116	20	+	27260157	DLD1	viability	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.38436813371524	[]	[]	-8	hSpCas9	negative selection	2613849
38748556	38748579	20	+	27260157	DLD1	viability	CGGGCCACTGCCGGTACCGCTGG	ACTR5	ENSG00000101442	-0.244901196957184	[]	[]	-2	hSpCas9	negative selection	2614473
38748526	38748549	20	-	27260157	DLD1	viability	CCGGGCCGGCCTCCAGCACTGGG	ACTR5	ENSG00000101442	0.349297415691076	[]	[]	4	hSpCas9	negative selection	2620699
38748521	38748544	20	+	27260157	DLD1	viability	CCGGACCCAGTGCTGGAGGCCGG	ACTR5	ENSG00000101442	0.139489950862222	[]	[]	3	hSpCas9	negative selection	2621438
38748460	38748483	20	+	27260157	DLD1	viability	GCTGGACGCGCGCTCCAAGATGG	ACTR5	ENSG00000101442	-0.728800951499852	[]	[]	-5	hSpCas9	negative selection	2641687
38748536	38748559	20	+	27260157	DLD1	viability	GAGGCCGGCCCGGTGGCACACGG	ACTR5	ENSG00000101442	-1.24755415055666	[]	[]	-7	hSpCas9	negative selection	2643707
38748652	38748675	20	-	27260157	HT1080	viability	CGCACACCGCGCGGAACTGCAGG	ACTR5	ENSG00000101442	-0.896661221960022	[]	[]	-8	hSpCas9	negative selection	2651468
38748590	38748613	20	+	27260157	HT1080	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-2.11418046344905	[]	[]	-9	hSpCas9	negative selection	2653342
38748516	38748539	20	-	27260157	HT1080	viability	CTCCAGCACTGGGTCCGGTGCGG	ACTR5	ENSG00000101442	-1.04293634543278	[]	[]	-8	hSpCas9	negative selection	2653772
38748641	38748664	20	-	27260157	HT1080	viability	CGGAACTGCAGGCGCGGCTCGGG	ACTR5	ENSG00000101442	-0.777358406920318	[]	[]	-8	hSpCas9	negative selection	2656167
38748562	38748585	20	+	27260157	HT1080	viability	ACTGCCGGTACCGCTGGTGCTGG	ACTR5	ENSG00000101442	-0.111834391013146	[]	[]	0	hSpCas9	negative selection	2656800
38748736	38748759	20	-	27260157	HT1080	viability	GCATCCAGCGCAGTGGCTCCAGG	ACTR5	ENSG00000101442	-1.3948496434487	[]	[]	-9	hSpCas9	negative selection	2659025
38748514	38748537	20	+	27260157	HT1080	viability	TGCCGCACCGGACCCAGTGCTGG	ACTR5	ENSG00000101442	-0.504171020507965	[]	[]	-7	hSpCas9	negative selection	2659702
38748496	38748519	20	-	27260157	HT1080	viability	CGGCACGGGCGTCGCGGAACGGG	ACTR5	ENSG00000101442	-1.28672173731288	[]	[]	-9	hSpCas9	negative selection	2661606
38748569	38748592	20	+	27260157	HT1080	viability	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	-1.25006258986907	[]	[]	-9	hSpCas9	negative selection	2663616
38748767	38748790	20	-	27260157	HT1080	viability	ACCGGCACGTTGCGGTCGAAGGG	ACTR5	ENSG00000101442	-1.66781186763628	[]	[]	-9	hSpCas9	negative selection	2680346
38748598	38748621	20	-	27260157	HT1080	viability	ACGCCCAGCCAGCGCGGACTTGG	ACTR5	ENSG00000101442	0.464857376880052	[]	[]	4	hSpCas9	negative selection	2680666
38748846	38748869	20	-	27260157	HT1080	viability	TACTCCGCCCTTCACCTGTGAGG	ACTR5	ENSG00000101442	-1.24107962298612	[]	[]	-9	hSpCas9	negative selection	2682287
38748510	38748533	20	-	27260157	HT1080	viability	CACTGGGTCCGGTGCGGCACGGG	ACTR5	ENSG00000101442	-0.0656078897982951	[]	[]	0	hSpCas9	negative selection	2683391
38748544	38748567	20	-	27260157	HT1080	viability	GCAGTGGCCCGTGTGCCACCGGG	ACTR5	ENSG00000101442	-0.046498551888908	[]	[]	0	hSpCas9	negative selection	2684803
38750093	38750116	20	+	27260157	HT1080	viability	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.399742046930629	[]	[]	-7	hSpCas9	negative selection	2689979
38748556	38748579	20	+	27260157	HT1080	viability	CGGGCCACTGCCGGTACCGCTGG	ACTR5	ENSG00000101442	0.292465806515737	[]	[]	2	hSpCas9	negative selection	2690603
38748526	38748549	20	-	27260157	HT1080	viability	CCGGGCCGGCCTCCAGCACTGGG	ACTR5	ENSG00000101442	-0.274578659606189	[]	[]	-4	hSpCas9	negative selection	2696829
38748521	38748544	20	+	27260157	HT1080	viability	CCGGACCCAGTGCTGGAGGCCGG	ACTR5	ENSG00000101442	0.205121555580597	[]	[]	2	hSpCas9	negative selection	2697568
38748460	38748483	20	+	27260157	HT1080	viability	GCTGGACGCGCGCTCCAAGATGG	ACTR5	ENSG00000101442	-0.152719558387137	[]	[]	0	hSpCas9	negative selection	2717817
38748536	38748559	20	+	27260157	HT1080	viability	GAGGCCGGCCCGGTGGCACACGG	ACTR5	ENSG00000101442	-0.563559371953375	[]	[]	-7	hSpCas9	negative selection	2719837
38748652	38748675	20	-	27260157	MKN45	viability	CGCACACCGCGCGGAACTGCAGG	ACTR5	ENSG00000101442	-1.12560895906543	[]	[]	-8	hSpCas9	negative selection	2727598
38748590	38748613	20	+	27260157	MKN45	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.977203483987596	[]	[]	-7	hSpCas9	negative selection	2729472
38748516	38748539	20	-	27260157	MKN45	viability	CTCCAGCACTGGGTCCGGTGCGG	ACTR5	ENSG00000101442	-0.219046412718956	[]	[]	-1	hSpCas9	negative selection	2729902
38748641	38748664	20	-	27260157	MKN45	viability	CGGAACTGCAGGCGCGGCTCGGG	ACTR5	ENSG00000101442	-0.699213302828574	[]	[]	-7	hSpCas9	negative selection	2732297
38748562	38748585	20	+	27260157	MKN45	viability	ACTGCCGGTACCGCTGGTGCTGG	ACTR5	ENSG00000101442	-0.447925439597048	[]	[]	-6	hSpCas9	negative selection	2732930
38748736	38748759	20	-	27260157	MKN45	viability	GCATCCAGCGCAGTGGCTCCAGG	ACTR5	ENSG00000101442	0.232265494280438	[]	[]	5	hSpCas9	negative selection	2735155
38748514	38748537	20	+	27260157	MKN45	viability	TGCCGCACCGGACCCAGTGCTGG	ACTR5	ENSG00000101442	-0.541272569761051	[]	[]	-6	hSpCas9	negative selection	2735832
38748496	38748519	20	-	27260157	MKN45	viability	CGGCACGGGCGTCGCGGAACGGG	ACTR5	ENSG00000101442	-2.09107652738563	[]	[]	-9	hSpCas9	negative selection	2737736
38748569	38748592	20	+	27260157	MKN45	viability	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	-1.05900796474104	[]	[]	-8	hSpCas9	negative selection	2739746
38748767	38748790	20	-	27260157	MKN45	viability	ACCGGCACGTTGCGGTCGAAGGG	ACTR5	ENSG00000101442	-0.323252026834134	[]	[]	-1	hSpCas9	negative selection	2756476
38748598	38748621	20	-	27260157	MKN45	viability	ACGCCCAGCCAGCGCGGACTTGG	ACTR5	ENSG00000101442	1.45985014899065	[]	[]	9	hSpCas9	negative selection	2756796
38748846	38748869	20	-	27260157	MKN45	viability	TACTCCGCCCTTCACCTGTGAGG	ACTR5	ENSG00000101442	-2.08798354324478	[]	[]	-9	hSpCas9	negative selection	2758417
38748510	38748533	20	-	27260157	MKN45	viability	CACTGGGTCCGGTGCGGCACGGG	ACTR5	ENSG00000101442	-0.929722977296669	[]	[]	-7	hSpCas9	negative selection	2759521
38748544	38748567	20	-	27260157	MKN45	viability	GCAGTGGCCCGTGTGCCACCGGG	ACTR5	ENSG00000101442	-0.476232133513327	[]	[]	-6	hSpCas9	negative selection	2760933
38750093	38750116	20	+	27260157	MKN45	viability	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.883799466404759	[]	[]	-7	hSpCas9	negative selection	2766109
38748556	38748579	20	+	27260157	MKN45	viability	CGGGCCACTGCCGGTACCGCTGG	ACTR5	ENSG00000101442	0.213820568208646	[]	[]	5	hSpCas9	negative selection	2766733
38748526	38748549	20	-	27260157	MKN45	viability	CCGGGCCGGCCTCCAGCACTGGG	ACTR5	ENSG00000101442	-0.114295250699699	[]	[]	0	hSpCas9	negative selection	2772959
38748521	38748544	20	+	27260157	MKN45	viability	CCGGACCCAGTGCTGGAGGCCGG	ACTR5	ENSG00000101442	0.984055960708064	[]	[]	8	hSpCas9	negative selection	2773698
38748460	38748483	20	+	27260157	MKN45	viability	GCTGGACGCGCGCTCCAAGATGG	ACTR5	ENSG00000101442	0.45070490049372	[]	[]	6	hSpCas9	negative selection	2793947
38748536	38748559	20	+	27260157	MKN45	viability	GAGGCCGGCCCGGTGGCACACGG	ACTR5	ENSG00000101442	-0.431238406722028	[]	[]	-6	hSpCas9	negative selection	2795967
38748652	38748675	20	-	27260157	RKO	viability	CGCACACCGCGCGGAACTGCAGG	ACTR5	ENSG00000101442	-1.46526881382411	[]	[]	-8	hSpCas9	negative selection	2803728
38748590	38748613	20	+	27260157	RKO	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-2.71981722172139	[]	[]	-9	hSpCas9	negative selection	2805602
38748516	38748539	20	-	27260157	RKO	viability	CTCCAGCACTGGGTCCGGTGCGG	ACTR5	ENSG00000101442	-1.82362777081353	[]	[]	-9	hSpCas9	negative selection	2806032
38748641	38748664	20	-	27260157	RKO	viability	CGGAACTGCAGGCGCGGCTCGGG	ACTR5	ENSG00000101442	-0.593760004109827	[]	[]	-7	hSpCas9	negative selection	2808427
38748562	38748585	20	+	27260157	RKO	viability	ACTGCCGGTACCGCTGGTGCTGG	ACTR5	ENSG00000101442	-0.412504891624422	[]	[]	-6	hSpCas9	negative selection	2809060
38748736	38748759	20	-	27260157	RKO	viability	GCATCCAGCGCAGTGGCTCCAGG	ACTR5	ENSG00000101442	-0.700540599038156	[]	[]	-7	hSpCas9	negative selection	2811285
38748514	38748537	20	+	27260157	RKO	viability	TGCCGCACCGGACCCAGTGCTGG	ACTR5	ENSG00000101442	-0.0852224548265008	[]	[]	0	hSpCas9	negative selection	2811962
38748496	38748519	20	-	27260157	RKO	viability	CGGCACGGGCGTCGCGGAACGGG	ACTR5	ENSG00000101442	-0.649761334693455	[]	[]	-7	hSpCas9	negative selection	2813866
38748569	38748592	20	+	27260157	RKO	viability	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	-1.2867425636018	[]	[]	-8	hSpCas9	negative selection	2815876
38748767	38748790	20	-	27260157	RKO	viability	ACCGGCACGTTGCGGTCGAAGGG	ACTR5	ENSG00000101442	-0.248013366223534	[]	[]	-1	hSpCas9	negative selection	2832606
38748598	38748621	20	-	27260157	RKO	viability	ACGCCCAGCCAGCGCGGACTTGG	ACTR5	ENSG00000101442	0.851567225462179	[]	[]	8	hSpCas9	negative selection	2832926
38748846	38748869	20	-	27260157	RKO	viability	TACTCCGCCCTTCACCTGTGAGG	ACTR5	ENSG00000101442	-1.13641178896739	[]	[]	-8	hSpCas9	negative selection	2834547
38748510	38748533	20	-	27260157	RKO	viability	CACTGGGTCCGGTGCGGCACGGG	ACTR5	ENSG00000101442	-2.79578794603617	[]	[]	-9	hSpCas9	negative selection	2835651
38748544	38748567	20	-	27260157	RKO	viability	GCAGTGGCCCGTGTGCCACCGGG	ACTR5	ENSG00000101442	-0.286883567409128	[]	[]	-5	hSpCas9	negative selection	2837063
38750093	38750116	20	+	27260157	RKO	viability	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.06363660927072	[]	[]	-8	hSpCas9	negative selection	2842239
38748556	38748579	20	+	27260157	RKO	viability	CGGGCCACTGCCGGTACCGCTGG	ACTR5	ENSG00000101442	0.018368860135164	[]	[]	0	hSpCas9	negative selection	2842863
38748526	38748549	20	-	27260157	RKO	viability	CCGGGCCGGCCTCCAGCACTGGG	ACTR5	ENSG00000101442	-0.588617539422303	[]	[]	-7	hSpCas9	negative selection	2849089
38748521	38748544	20	+	27260157	RKO	viability	CCGGACCCAGTGCTGGAGGCCGG	ACTR5	ENSG00000101442	0.425017646319024	[]	[]	2	hSpCas9	negative selection	2849828
38748460	38748483	20	+	27260157	RKO	viability	GCTGGACGCGCGCTCCAAGATGG	ACTR5	ENSG00000101442	0.529589865466153	[]	[]	3	hSpCas9	negative selection	2870077
38748536	38748559	20	+	27260157	RKO	viability	GAGGCCGGCCCGGTGGCACACGG	ACTR5	ENSG00000101442	-0.911208652804786	[]	[]	-8	hSpCas9	negative selection	2872097
38748652	38748675	20	-	27260157	SF268	viability	CGCACACCGCGCGGAACTGCAGG	ACTR5	ENSG00000101442	-1.39617141814506	[]	[]	-8	hSpCas9	negative selection	2879858
38748590	38748613	20	+	27260157	SF268	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-1.87665284420068	[]	[]	-8	hSpCas9	negative selection	2881732
38748516	38748539	20	-	27260157	SF268	viability	CTCCAGCACTGGGTCCGGTGCGG	ACTR5	ENSG00000101442	-0.182586163327092	[]	[]	-1	hSpCas9	negative selection	2882162
38748641	38748664	20	-	27260157	SF268	viability	CGGAACTGCAGGCGCGGCTCGGG	ACTR5	ENSG00000101442	-0.395404001624035	[]	[]	-3	hSpCas9	negative selection	2884557
38748562	38748585	20	+	27260157	SF268	viability	ACTGCCGGTACCGCTGGTGCTGG	ACTR5	ENSG00000101442	0.0590040420493876	[]	[]	0	hSpCas9	negative selection	2885190
38748736	38748759	20	-	27260157	SF268	viability	GCATCCAGCGCAGTGGCTCCAGG	ACTR5	ENSG00000101442	0.133681573206549	[]	[]	0	hSpCas9	negative selection	2887415
38748514	38748537	20	+	27260157	SF268	viability	TGCCGCACCGGACCCAGTGCTGG	ACTR5	ENSG00000101442	-0.0156230415414403	[]	[]	0	hSpCas9	negative selection	2888092
38748496	38748519	20	-	27260157	SF268	viability	CGGCACGGGCGTCGCGGAACGGG	ACTR5	ENSG00000101442	-0.876105310540973	[]	[]	-6	hSpCas9	negative selection	2889996
38748569	38748592	20	+	27260157	SF268	viability	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	-0.141703092827652	[]	[]	-1	hSpCas9	negative selection	2892006
38748767	38748790	20	-	27260157	SF268	viability	ACCGGCACGTTGCGGTCGAAGGG	ACTR5	ENSG00000101442	0.415993935503372	[]	[]	4	hSpCas9	negative selection	2908736
38748598	38748621	20	-	27260157	SF268	viability	ACGCCCAGCCAGCGCGGACTTGG	ACTR5	ENSG00000101442	1.31018811572287	[]	[]	9	hSpCas9	negative selection	2909056
38748846	38748869	20	-	27260157	SF268	viability	TACTCCGCCCTTCACCTGTGAGG	ACTR5	ENSG00000101442	-0.122328656753946	[]	[]	-1	hSpCas9	negative selection	2910677
38748510	38748533	20	-	27260157	SF268	viability	CACTGGGTCCGGTGCGGCACGGG	ACTR5	ENSG00000101442	-1.87195239830713	[]	[]	-8	hSpCas9	negative selection	2911781
38748544	38748567	20	-	27260157	SF268	viability	GCAGTGGCCCGTGTGCCACCGGG	ACTR5	ENSG00000101442	-0.0443063904137675	[]	[]	0	hSpCas9	negative selection	2913193
38750093	38750116	20	+	27260157	SF268	viability	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.568116004093397	[]	[]	-4	hSpCas9	negative selection	2918369
38748556	38748579	20	+	27260157	SF268	viability	CGGGCCACTGCCGGTACCGCTGG	ACTR5	ENSG00000101442	0.429059970365858	[]	[]	7	hSpCas9	negative selection	2918993
38748526	38748549	20	-	27260157	SF268	viability	CCGGGCCGGCCTCCAGCACTGGG	ACTR5	ENSG00000101442	-0.118027185850042	[]	[]	-1	hSpCas9	negative selection	2925219
38748521	38748544	20	+	27260157	SF268	viability	CCGGACCCAGTGCTGGAGGCCGG	ACTR5	ENSG00000101442	0.735015262315527	[]	[]	8	hSpCas9	negative selection	2925958
38748460	38748483	20	+	27260157	SF268	viability	GCTGGACGCGCGCTCCAAGATGG	ACTR5	ENSG00000101442	-0.115360703912736	[]	[]	-1	hSpCas9	negative selection	2946207
38748536	38748559	20	+	27260157	SF268	viability	GAGGCCGGCCCGGTGGCACACGG	ACTR5	ENSG00000101442	0.381935985326549	[]	[]	4	hSpCas9	negative selection	2948227
38755054	38755077	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGAGGAGAAACAAGAAAGGCGG	ACTR5	ENSG00000101442	-0.20443117052687115	[4,4]	[3,2]	-3	hSpCas9	positive selection	2968764
38748647	38748670	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCGCGCCTGCAGTTCCGCGCGG	ACTR5	ENSG00000101442	-0.8902016607939947	[2,3]	[1,0]	-8	hSpCas9	positive selection	2968765
38750054	38750077	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCATTTGCCGTGAATACAGTGGG	ACTR5	ENSG00000101442	-0.30922070351199693	[4,3]	[3,1]	-4	hSpCas9	positive selection	2968766
38750094	38750117	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.36656320348531507	[3,3]	[0,3]	-5	hSpCas9	positive selection	2968767
38755054	38755077	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGAGGAGAAACAAGAAAGGCGG	ACTR5	ENSG00000101442	0.10483719381016979	[4,4]	[4,2]	1	hSpCas9	positive selection	3036622
38748647	38748670	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCGCGCCTGCAGTTCCGCGCGG	ACTR5	ENSG00000101442	-0.8997439549642882	[2,2]	[0,0]	-9	hSpCas9	positive selection	3036623
38750054	38750077	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCATTTGCCGTGAATACAGTGGG	ACTR5	ENSG00000101442	-0.6726076103123046	[4,4]	[1,1]	-8	hSpCas9	positive selection	3036624
38750094	38750117	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.29597731988428877	[3,3]	[2,1]	-4	hSpCas9	positive selection	3036625
38756000	38756023		+	24336571	A375	resistance to PLX after 7 days	AGTCAACCTCGAGGTGGATGTGG	ACTR5	ENSG00000101442	-0.08794618111821162	[3,6]	[4,5]	-3	hSpCas9	positive selection	3160119
38755923	38755946		-	24336571	A375	resistance to PLX after 7 days	ATGTAGGACTGCAGCTCTTCTGG	ACTR5	ENSG00000101442	0.08978912424367513	[17,19]	[16,22]	3	hSpCas9	positive selection	3160130
38750160	38750183		+	24336571	A375	resistance to PLX after 7 days	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.10803033018064229	[8,8]	[8,9]	3	hSpCas9	positive selection	3160141
38756000	38756023		+	24336571	A375	resistance to PLX after 14 days	AGTCAACCTCGAGGTGGATGTGG	ACTR5	ENSG00000101442	0.6198070264535316	[2,3]	[2,1]	5	hSpCas9	positive selection	3217912
38755923	38755946		-	24336571	A375	resistance to PLX after 14 days	ATGTAGGACTGCAGCTCTTCTGG	ACTR5	ENSG00000101442	-0.08716236464159866	[10,19]	[7,4]	-1	hSpCas9	positive selection	3217923
38750160	38750183		+	24336571	A375	resistance to PLX after 14 days	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.33834850694541874	[9,8]	[2,3]	-4	hSpCas9	positive selection	3217934
38756000	38756023		+	24336571	A375	viability after 7 days	AGTCAACCTCGAGGTGGATGTGG	ACTR5	ENSG00000101442	-0.24704066140394754	[6]	[3,6]	-4	hSpCas9	negative selection	3275705
38755923	38755946		-	24336571	A375	viability after 7 days	ATGTAGGACTGCAGCTCTTCTGG	ACTR5	ENSG00000101442	0.6655086218197849	[11]	[17,19]	8	hSpCas9	negative selection	3275716
38750160	38750183		+	24336571	A375	viability after 7 days	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.41300152454648814	[6]	[8,8]	6	hSpCas9	negative selection	3275727
38756000	38756023		+	24336571	A375	viability after 14 days	AGTCAACCTCGAGGTGGATGTGG	ACTR5	ENSG00000101442	-0.784676260548208	[6]	[2,3]	-7	hSpCas9	negative selection	3333498
38755923	38755946		-	24336571	A375	viability after 14 days	ATGTAGGACTGCAGCTCTTCTGG	ACTR5	ENSG00000101442	0.43040623921367915	[11]	[10,19]	5	hSpCas9	negative selection	3333509
38750160	38750183		+	24336571	A375	viability after 14 days	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.528079919450321	[6]	[9,8]	6	hSpCas9	negative selection	3333520
38752266	38752289	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.8812216665848334	[251,311]	[0,0]	-6	hSpCas9	positive selection	3335451
38752144	38752167	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	-0.6287488821756093	[245,226]	[0,0]	-4	hSpCas9	positive selection	3335452
38755156	38755179	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	0.20062652052256089	[152,112]	[0,0]	1	hSpCas9	positive selection	3335453
38750160	38750183	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.28004628794591846	[125,125]	[0,0]	1	hSpCas9	positive selection	3354701
38756006	38756029	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-1.3829187247765107	[398,398]	[0,0]	-8	hSpCas9	positive selection	3354702
38750160	38750183	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-1.181465641132426	[346,346]	[0,0]	-7	hSpCas9	positive selection	3354703
38755053	38755076	20	+	26780180	HT29	viability (Avana library 4 designs)	CTGAGGAGAAACAAGAAAGGCGG	ACTR5	ENSG00000101442	2.84313102049351	[]	[]	8	hSpCas9	negative selection	3404714
38748646	38748669	20	+	26780180	HT29	viability (Avana library 4 designs)	GCCGCGCCTGCAGTTCCGCGCGG	ACTR5	ENSG00000101442	0.973761377783401	[]	[]	4	hSpCas9	negative selection	3404715
38750054	38750077	20	-	26780180	HT29	viability (Avana library 4 designs)	TCATTTGCCGTGAATACAGTGGG	ACTR5	ENSG00000101442	1.81386738028376	[]	[]	7	hSpCas9	negative selection	3404716
38750093	38750116	20	+	26780180	HT29	viability (Avana library 4 designs)	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	3.05304179365347	[]	[]	8	hSpCas9	negative selection	3404717
38748646	38748669	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCGCGCCTGCAGTTCCGCGCGG	ACTR5	ENSG00000101442	3.20564670812533	[]	[]	5	hSpCas9	negative selection	3476385
38755053	38755076	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGAGGAGAAACAAGAAAGGCGG	ACTR5	ENSG00000101442	-0.913702150711	[]	[]	-1	hSpCas9	negative selection	3476386
38750093	38750116	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-6.49756590385593	[]	[]	-6	hSpCas9	negative selection	3476387
38750054	38750077	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCATTTGCCGTGAATACAGTGGG	ACTR5	ENSG00000101442	-9.93446784515923	[]	[]	-7	hSpCas9	negative selection	3476388
38748569	38748592	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	2.77707703054646	[]	[]	4	hSpCas9	negative selection	3476389
38752245	38752268	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGCAGAATCTCCTCCATGCGG	ACTR5	ENSG00000101442	2.13892981598125	[]	[]	3	hSpCas9	negative selection	3476390
38748646	38748669	20	+	26780180	A375	viability (Avana lentiGuide)	GCCGCGCCTGCAGTTCCGCGCGG	ACTR5	ENSG00000101442	1.93123314687447	[]	[]	2	hSpCas9	negative selection	3585044
38755053	38755076	20	+	26780180	A375	viability (Avana lentiGuide)	CTGAGGAGAAACAAGAAAGGCGG	ACTR5	ENSG00000101442	3.01086443886612	[]	[]	3	hSpCas9	negative selection	3585045
38750093	38750116	20	+	26780180	A375	viability (Avana lentiGuide)	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	6.41910804125236	[]	[]	5	hSpCas9	negative selection	3585046
38750054	38750077	20	-	26780180	A375	viability (Avana lentiGuide)	TCATTTGCCGTGAATACAGTGGG	ACTR5	ENSG00000101442	4.88051174215611	[]	[]	4	hSpCas9	negative selection	3585047
38748569	38748592	20	+	26780180	A375	viability (Avana lentiGuide)	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	2.33168172714725	[]	[]	2	hSpCas9	negative selection	3585048
38752245	38752268	20	-	26780180	A375	viability (Avana lentiGuide)	CATGCAGAATCTCCTCCATGCGG	ACTR5	ENSG00000101442	1.16980821858529	[]	[]	1	hSpCas9	negative selection	3585049
38748646	38748669	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCGCGCCTGCAGTTCCGCGCGG	ACTR5	ENSG00000101442	0.4603800649256817	[4]	[5,6]	9	hSpCas9	positive selection	3693703
38755053	38755076	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGAGGAGAAACAAGAAAGGCGG	ACTR5	ENSG00000101442	-0.04075817032297979	[5]	[5,5]	0	hSpCas9	positive selection	3693704
38750093	38750116	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.7529574050052548	[4]	[2,1]	-8	hSpCas9	positive selection	3693705
38750054	38750077	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATTTGCCGTGAATACAGTGGG	ACTR5	ENSG00000101442	-1.0139276409847944	[4]	[2,1]	-8	hSpCas9	positive selection	3693706
38748569	38748592	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	0.331394529068607	[4]	[5,5]	8	hSpCas9	positive selection	3693707
38752245	38752268	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGCAGAATCTCCTCCATGCGG	ACTR5	ENSG00000101442	0.2572206006805414	[4]	[5,5]	7	hSpCas9	positive selection	3693708
38748646	38748669	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCGCGCCTGCAGTTCCGCGCGG	ACTR5	ENSG00000101442	-0.06615416219943601	[5]	[5,2]	-1	hSpCas9	positive selection	3802310
38755053	38755076	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGAGGAGAAACAAGAAAGGCGG	ACTR5	ENSG00000101442	-0.5746037143714725	[6]	[4,2]	-6	hSpCas9	positive selection	3802311
38750093	38750116	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.2942767824715171	[5]	[1,1]	-9	hSpCas9	positive selection	3802312
38750054	38750077	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATTTGCCGTGAATACAGTGGG	ACTR5	ENSG00000101442	0.19396527617272943	[5]	[4,5]	5	hSpCas9	positive selection	3802313
38748569	38748592	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACCGCTGGTGCTGGACAACGG	ACTR5	ENSG00000101442	0.18777277298319145	[4]	[4,3]	4	hSpCas9	positive selection	3802314
38752245	38752268	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGCAGAATCTCCTCCATGCGG	ACTR5	ENSG00000101442	0.23221407520668066	[5]	[5,4]	6	hSpCas9	positive selection	3802315
38752144	38752167	20	+	26780180	A375	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	1.0195722012634	[]	[]	5	hSpCas9	negative selection	3910912
38750160	38750183	20	+	26780180	A375	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.809351577378884	[]	[]	3	hSpCas9	negative selection	3910913
38750160	38750183	20	-	26780180	A375	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.697657363881064	[]	[]	2	hSpCas9	negative selection	3910914
38752266	38752289	20	+	26780180	A375	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	0.942974697806424	[]	[]	4	hSpCas9	negative selection	3910915
38756006	38756029	20	-	26780180	A375	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.92529345565396	[]	[]	4	hSpCas9	negative selection	3910916
38755156	38755179	20	-	26780180	A375	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	1.09728401501755	[]	[]	5	hSpCas9	negative selection	3910917
38752144	38752167	20	+	26780180	HT29	viability (GeCKOv2 library)	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.0914428664055594	[]	[]	0	hSpCas9	negative selection	4018878
38750160	38750183	20	+	26780180	HT29	viability (GeCKOv2 library)	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	1.2021636107271	[]	[]	6	hSpCas9	negative selection	4018879
38750160	38750183	20	-	26780180	HT29	viability (GeCKOv2 library)	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	1.03734742500412	[]	[]	5	hSpCas9	negative selection	4018880
38752266	38752289	20	+	26780180	HT29	viability (GeCKOv2 library)	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	0.257324824145525	[]	[]	0	hSpCas9	negative selection	4018881
38756006	38756029	20	-	26780180	HT29	viability (GeCKOv2 library)	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.277867996672909	[]	[]	0	hSpCas9	negative selection	4018882
38755156	38755179	20	-	26780180	HT29	viability (GeCKOv2 library)	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	1.2695442410902	[]	[]	6	hSpCas9	negative selection	4018883
38756000	38756023	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTCAACCTCGAGGTGGATGTGG	ACTR5	ENSG00000101442	-0.23353258702669688	[2]	[1,0]	-5	hSpCas9	positive selection	4188183
38755923	38755946	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGTAGGACTGCAGCTCTTCTGG	ACTR5	ENSG00000101442	0.009480322762758009	[3]	[2,2]	0	hSpCas9	positive selection	4188194
38750160	38750183	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.27601360534896424	[3]	[1,1]	-6	hSpCas9	positive selection	4188205
38756000	38756023	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTCAACCTCGAGGTGGATGTGG	ACTR5	ENSG00000101442	0.7250786560615472	[3]	[0,0,0,4]	5	hSpCas9	positive selection	4252205
38755923	38755946	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGTAGGACTGCAGCTCTTCTGG	ACTR5	ENSG00000101442	1.1468351175843512	[3]	[4,0,1,5]	8	hSpCas9	positive selection	4252216
38750160	38750183	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.10871028069936388	[3]	[0,0,4,0]	-1	hSpCas9	positive selection	4252227
38752266	38752289	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	0.31476321865147844	[4]	[4,4]	6	hSpCas9	positive selection	4254371
38752144	38752167	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.3773654203620916	[3]	[4,3]	7	hSpCas9	positive selection	4254372
38755156	38755179	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.006184129965217718	[3]	[2,2]	0	hSpCas9	positive selection	4254373
38750160	38750183	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.1733791125332422	[2]	[3,1]	3	hSpCas9	positive selection	4318654
38756006	38756029	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.1550171111758073	[3]	[4,2]	3	hSpCas9	positive selection	4318655
38750160	38750183	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.6287056637670422	[3]	[4,5]	9	hSpCas9	positive selection	4318656
38748591	38748613	20	+	27760321	OCIAML3	viability	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.46357101313740956	[1132,1100]	[679,575]	-5	hSpCas9	negative selection	4375956
38748768	38748790	20	-	27760321	OCIAML3	viability	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.08502703546431219	[478,383]	[318,403]	1	hSpCas9	negative selection	4375957
38750104	38750126	20	+	27760321	OCIAML3	viability	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.3434508630384945	[467,403]	[277,254]	-4	hSpCas9	negative selection	4375958
38750162	38750184	20	+	27760321	OCIAML3	viability	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	0.12881259173501314	[569,491]	[342,595]	1	hSpCas9	negative selection	4375959
38752280	38752302	20	+	27760321	OCIAML3	viability	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	-0.44315694153410573	[511,354]	[219,280]	-4	hSpCas9	negative selection	4375960
38748591	38748613	20	+	27760321	OCIAML2	viability	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.2257732932883878	[1132,1100]	[599,1003]	-3	hSpCas9	negative selection	4459419
38748768	38748790	20	-	27760321	OCIAML2	viability	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.01167553657839902	[478,383]	[304,408]	0	hSpCas9	negative selection	4459420
38750104	38750126	20	+	27760321	OCIAML2	viability	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.17717607644250644	[467,403]	[276,355]	-2	hSpCas9	negative selection	4459421
38750162	38750184	20	+	27760321	OCIAML2	viability	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.02666483032529743	[569,491]	[300,577]	0	hSpCas9	negative selection	4459422
38752280	38752302	20	+	27760321	OCIAML2	viability	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	-0.35399772183411893	[511,354]	[303,227]	-4	hSpCas9	negative selection	4459423
38748591	38748613	20	+	27760321	MV411	viability	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-1.4460945265881449	[1132,1100]	[149,452]	-7	hSpCas9	negative selection	4542882
38748768	38748790	20	-	27760321	MV411	viability	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.3342966194384633	[478,383]	[276,476]	2	hSpCas9	negative selection	4542883
38750104	38750126	20	+	27760321	MV411	viability	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	0.04594936159006479	[467,403]	[312,270]	0	hSpCas9	negative selection	4542884
38750162	38750184	20	+	27760321	MV411	viability	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-1.3527966072970088	[569,491]	[159,101]	-7	hSpCas9	negative selection	4542885
38752280	38752302	20	+	27760321	MV411	viability	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	-1.2089266501778133	[511,354]	[21,272]	-7	hSpCas9	negative selection	4542886
38748591	38748613	20	+	27760321	HL60	viability	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	0.29152898283905104	[1132,1100]	[957,1289]	3	hSpCas9	negative selection	4626345
38748768	38748790	20	-	27760321	HL60	viability	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.49227241357915136	[478,383]	[375,616]	6	hSpCas9	negative selection	4626346
38750104	38750126	20	+	27760321	HL60	viability	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	0.3201356067255619	[467,403]	[440,445]	4	hSpCas9	negative selection	4626347
38750162	38750184	20	+	27760321	HL60	viability	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	0.24865432936147625	[569,491]	[544,480]	3	hSpCas9	negative selection	4626348
38752280	38752302	20	+	27760321	HL60	viability	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	1.206787083393001	[511,354]	[655,968]	9	hSpCas9	negative selection	4626349
38748591	38748613	20	+	27760321	HT1080	viability	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-1.3305922062128872	[1100,858]	[180,126]	-5	hSpCas9	negative selection	4709808
38748768	38748790	20	-	27760321	HT1080	viability	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	-0.13803864948522904	[383,299]	[119,127]	0	hSpCas9	negative selection	4709809
38750104	38750126	20	+	27760321	HT1080	viability	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.05706661370883152	[403,314]	[182,87]	0	hSpCas9	negative selection	4709810
38750162	38750184	20	+	27760321	HT1080	viability	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.0050986019052148834	[491,383]	[265,72]	0	hSpCas9	negative selection	4709811
38752280	38752302	20	+	27760321	HT1080	viability	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	-1.0669593040344472	[354,276]	[82,34]	-4	hSpCas9	negative selection	4709812
38748591	38748613	20	+	27760321	HT29	viability after 7 days	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.21485686554324812	[1100,858]	[1116,1031,1109]	-3	hSpCas9	negative selection	4793271
38748768	38748790	20	-	27760321	HT29	viability after 7 days	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	-0.25633544772666794	[383,299]	[547,353,231]	-4	hSpCas9	negative selection	4793272
38750104	38750126	20	+	27760321	HT29	viability after 7 days	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.20956863871036294	[403,314]	[550,234,432]	-3	hSpCas9	negative selection	4793273
38750162	38750184	20	+	27760321	HT29	viability after 7 days	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.3198607962622158	[491,383]	[486,389,479]	-4	hSpCas9	negative selection	4793274
38752280	38752302	20	+	27760321	HT29	viability after 7 days	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	0.42522424020134997	[354,276]	[512,756,366]	6	hSpCas9	negative selection	4793275
38748591	38748613	20	+	27760321	HT29	viability after 25 days	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.5292302963041039	[1100,858]	[612,880,850]	-5	hSpCas9	negative selection	4876734
38748768	38748790	20	-	27760321	HT29	viability after 25 days	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.654722974570297	[383,299]	[625,494,735]	7	hSpCas9	negative selection	4876735
38750104	38750126	20	+	27760321	HT29	viability after 25 days	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.6838714986555802	[403,314]	[218,260,292]	-5	hSpCas9	negative selection	4876736
38750162	38750184	20	+	27760321	HT29	viability after 25 days	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.1077322958838727	[491,383]	[400,478,522]	-1	hSpCas9	negative selection	4876737
38752280	38752302	20	+	27760321	HT29	viability after 25 days	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	-0.2789166213552873	[354,276]	[280,284,330]	-3	hSpCas9	negative selection	4876738
38748591	38748613	20	+	27760321	HT29	viability after 22 days	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.6444538021019903	[1100,858]	[851,573,744]	-5	hSpCas9	negative selection	4960197
38748768	38748790	20	-	27760321	HT29	viability after 22 days	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.14884467198152462	[383,299]	[380,353,582]	1	hSpCas9	negative selection	4960198
38750104	38750126	20	+	27760321	HT29	viability after 22 days	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.6197955176318711	[403,314]	[120,355,338]	-5	hSpCas9	negative selection	4960199
38750162	38750184	20	+	27760321	HT29	viability after 22 days	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.33354533931893027	[491,383]	[450,366,385]	-3	hSpCas9	negative selection	4960200
38752280	38752302	20	+	27760321	HT29	viability after 22 days	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	0.020829851893238244	[354,276]	[460,423,222]	0	hSpCas9	negative selection	4960201
38748591	38748613	20	+	27760321	HT29	viability after 19 days	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.03729210904093727	[1100,858]	[1387,1234,698]	0	hSpCas9	negative selection	5043660
38748768	38748790	20	-	27760321	HT29	viability after 19 days	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.20944191252105226	[383,299]	[260,582,490]	2	hSpCas9	negative selection	5043661
38750104	38750126	20	+	27760321	HT29	viability after 19 days	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.7984978397855431	[403,314]	[333,116,266]	-6	hSpCas9	negative selection	5043662
38750162	38750184	20	+	27760321	HT29	viability after 19 days	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.8365212686164029	[491,383]	[354,396,103]	-6	hSpCas9	negative selection	5043663
38752280	38752302	20	+	27760321	HT29	viability after 19 days	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	0.11692083928510663	[354,276]	[229,683,249]	1	hSpCas9	negative selection	5043664
38748591	38748613	20	+	27760321	HT29	viability after 16 days	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.05669037967718071	[1100,858]	[889,739,1524]	0	hSpCas9	negative selection	5127123
38748768	38748790	20	-	27760321	HT29	viability after 16 days	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.6785144323213231	[383,299]	[804,397,657]	7	hSpCas9	negative selection	5127124
38750104	38750126	20	+	27760321	HT29	viability after 16 days	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.013360686181734414	[403,314]	[359,464,364]	0	hSpCas9	negative selection	5127125
38750162	38750184	20	+	27760321	HT29	viability after 16 days	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.0880499130549075	[491,383]	[687,362,355]	-1	hSpCas9	negative selection	5127126
38752280	38752302	20	+	27760321	HT29	viability after 16 days	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	0.028285076183262536	[354,276]	[289,317,467]	0	hSpCas9	negative selection	5127127
38748591	38748613	20	+	27760321	HT29	viability after 13 days	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.4391317321528869	[1100,858]	[639,1157,724]	-5	hSpCas9	negative selection	5210586
38748768	38748790	20	-	27760321	HT29	viability after 13 days	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.4151351970687806	[383,299]	[452,616,517]	5	hSpCas9	negative selection	5210587
38750104	38750126	20	+	27760321	HT29	viability after 13 days	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.11964056479162165	[403,314]	[257,479,411]	-1	hSpCas9	negative selection	5210588
38750162	38750184	20	+	27760321	HT29	viability after 13 days	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.3462382123014302	[491,383]	[267,320,597]	-4	hSpCas9	negative selection	5210589
38752280	38752302	20	+	27760321	HT29	viability after 13 days	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	0.45898536784009164	[354,276]	[537,647,335]	6	hSpCas9	negative selection	5210590
38748591	38748613	20	+	27760321	HT29	viability after 10 days	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.677707886812463	[1100,858]	[903,609,775]	-7	hSpCas9	negative selection	5294049
38748768	38748790	20	-	27760321	HT29	viability after 10 days	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.4984797430624066	[383,299]	[610,564,631]	6	hSpCas9	negative selection	5294050
38750104	38750126	20	+	27760321	HT29	viability after 10 days	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	-0.3678922448592512	[403,314]	[288,346,405]	-5	hSpCas9	negative selection	5294051
38750162	38750184	20	+	27760321	HT29	viability after 10 days	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.06609651193536162	[491,383]	[450,412,695]	-1	hSpCas9	negative selection	5294052
38752280	38752302	20	+	27760321	HT29	viability after 10 days	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	0.016446775809622616	[354,276]	[418,487,294]	0	hSpCas9	negative selection	5294053
38748591	38748613	20	+	27760321	MOLM13	viability	GGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.9440166286752734	[1132,1100]	[122,502]	-5	hSpCas9	negative selection	5377512
38748768	38748790	20	-	27760321	MOLM13	viability	ACCGGCACGTTGCGGTCGAAGG	ACTR5	ENSG00000101442	0.9225729475250614	[478,383]	[447,467]	6	hSpCas9	negative selection	5377513
38750104	38750126	20	+	27760321	MOLM13	viability	GGATTCCCAAGGTTGCCTATGG	ACTR5	ENSG00000101442	0.05282743256736122	[467,403]	[106,379]	0	hSpCas9	negative selection	5377514
38750162	38750184	20	+	27760321	MOLM13	viability	AAAGAACTCGATGTGCAGTGGG	ACTR5	ENSG00000101442	-0.7237255980790777	[569,491]	[208,156]	-4	hSpCas9	negative selection	5377515
38752280	38752302	20	+	27760321	MOLM13	viability	TCGCTGAGGATTATGTGGAAGG	ACTR5	ENSG00000101442	0.4574907214977947	[511,354]	[419,256]	3	hSpCas9	negative selection	5377516
38748460	38748483	20	+	27661255	K562	viability	GCTGGACGCGCGCTCCAAGATGG	ACTR5	ENSG00000101442	-0.11400901866553337	[360,504]	[321,313]	-4	dCas9-KRAB	negative selection	5460785
38748463	38748486	20	+	27661255	K562	viability	GGACGCGCGCTCCAAGATGGCGG	ACTR5	ENSG00000101442	-0.6996353146219269	[644,655]	[348,294]	-8	dCas9-KRAB	negative selection	5460786
38748832	38748855	20	+	27661255	K562	viability	GCACCTGGGTGTCTCCTCACAGG	ACTR5	ENSG00000101442	-0.6535496416620826	[538,369]	[247,218]	-8	dCas9-KRAB	negative selection	5460787
38748839	38748862	20	+	27661255	K562	viability	GGTGTCTCCTCACAGGTGAAGGG	ACTR5	ENSG00000101442	-0.37294560617059486	[1323,1144]	[790,739]	-7	dCas9-KRAB	negative selection	5460788
38752266	38752289	20	+	27260156	BXPC3	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.19484719534979456	[1256]	[1084,993,1196,1350]	-4	hSpCas9	negative selection	5526831
38752144	38752167	20	+	27260156	BXPC3	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.33168560297548877	[894]	[1074,1026,1376,1256]	7	hSpCas9	negative selection	5526832
38755156	38755179	20	-	27260156	BXPC3	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.14316036627509776	[504]	[468,519,438,478]	-3	hSpCas9	negative selection	5526833
38750160	38750183	20	+	27260156	BXPC3	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.08856067313157978	[392]	[392,382,349,419]	-2	hSpCas9	negative selection	5591114
38756006	38756029	20	-	27260156	BXPC3	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.01274079346772683	[835]	[783,786,875,1119]	0	hSpCas9	negative selection	5591115
38750160	38750183	20	-	27260156	BXPC3	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.01043925307762028	[961]	[736,943,1166,1265]	0	hSpCas9	negative selection	5591116
38752266	38752289	20	+	27260156	A673	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.26392738431893115	[1256]	[1356,1173,1253,1253]	-6	hSpCas9	negative selection	5648082
38752144	38752167	20	+	27260156	A673	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.21294692728200826	[894]	[1366,1102,1255,1272]	5	hSpCas9	negative selection	5648083
38755156	38755179	20	-	27260156	A673	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.14692662171824938	[504]	[756,440,400,622]	-4	hSpCas9	negative selection	5648084
38750160	38750183	20	+	27260156	A673	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.1555757029423792	[392]	[519,438,371,370]	-4	hSpCas9	negative selection	5712365
38756006	38756029	20	-	27260156	A673	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.06827064695907925	[835]	[1114,963,1069,1068]	1	hSpCas9	negative selection	5712366
38750160	38750183	20	-	27260156	A673	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.236774200003269	[961]	[1105,973,928,921]	-5	hSpCas9	negative selection	5712367
38752266	38752289	20	+	27260156	A375	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.5201358890069365	[1256]	[1296,963,1051,798]	-6	hSpCas9	negative selection	5769333
38752144	38752167	20	+	27260156	A375	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.5194968209509215	[894]	[1297,1619,1776,1328]	7	hSpCas9	negative selection	5769334
38755156	38755179	20	-	27260156	A375	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.4783325553915438	[504]	[296,402,544,440]	-6	hSpCas9	negative selection	5769335
38750160	38750183	20	+	27260156	A375	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.0046341411438820534	[392]	[525,490,473,354]	0	hSpCas9	negative selection	5833616
38756006	38756029	20	-	27260156	A375	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.11785262499792593	[835]	[762,998,792,1036]	-2	hSpCas9	negative selection	5833617
38750160	38750183	20	-	27260156	A375	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.06701736426974292	[961]	[1365,1154,1226,977]	1	hSpCas9	negative selection	5833618
38752266	38752289	20	+	27260156	COLO741	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.31318766414000176	[1256]	[1295,1364,1219]	-6	hSpCas9	negative selection	5890584
38752144	38752167	20	+	27260156	COLO741	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.36191538793124944	[894]	[1645,1497,1289]	7	hSpCas9	negative selection	5890585
38755156	38755179	20	-	27260156	COLO741	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.08735251455167979	[504]	[772,518,546]	-2	hSpCas9	negative selection	5890586
38750160	38750183	20	+	27260156	COLO741	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.32386180490371125	[392]	[573,242,399]	-6	hSpCas9	negative selection	5954867
38756006	38756029	20	-	27260156	COLO741	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.03847563045256819	[835]	[1203,895,1031]	-1	hSpCas9	negative selection	5954868
38750160	38750183	20	-	27260156	COLO741	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.06858375076033829	[961]	[1374,893,1254]	-1	hSpCas9	negative selection	5954869
38752266	38752289	20	+	27260156	CAL120	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.7253401033702801	[1256]	[1091,883,884]	-7	hSpCas9	negative selection	6011835
38752144	38752167	20	+	27260156	CAL120	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.628270665516795	[894]	[2096,2056,1077]	8	hSpCas9	negative selection	6011836
38755156	38755179	20	-	27260156	CAL120	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.5933644425590623	[504]	[621,393,266]	-7	hSpCas9	negative selection	6011837
38750160	38750183	20	+	27260156	CAL120	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.4158129084409958	[392]	[455,398,259]	-6	hSpCas9	negative selection	6076118
38756006	38756029	20	-	27260156	CAL120	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.04185904950689845	[835]	[886,1133,991]	0	hSpCas9	negative selection	6076119
38750160	38750183	20	-	27260156	CAL120	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.048805660166494125	[961]	[1234,1415,1065]	0	hSpCas9	negative selection	6076120
38752266	38752289	20	+	27260156	CADOES1	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.34230411595195576	[1256]	[889,961,1035,795]	-5	hSpCas9	negative selection	6133086
38752144	38752167	20	+	27260156	CADOES1	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.49285527187172107	[894]	[1317,1172,899,1298]	7	hSpCas9	negative selection	6133087
38755156	38755179	20	-	27260156	CADOES1	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.4312896950711601	[504]	[363,340,344,342]	-6	hSpCas9	negative selection	6133088
38750160	38750183	20	+	27260156	CADOES1	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.08425254463337123	[392]	[307,323,428,492]	1	hSpCas9	negative selection	6197369
38756006	38756029	20	-	27260156	CADOES1	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.16827442668210446	[835]	[696,753,518,801]	-3	hSpCas9	negative selection	6197370
38750160	38750183	20	-	27260156	CADOES1	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.09576126414011354	[961]	[840,938,1131,910]	1	hSpCas9	negative selection	6197371
38752266	38752289	20	+	27260156	EWS502	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.1224742565577761	[1256]	[1215,1197,1310,1160]	-2	hSpCas9	negative selection	6254337
38752144	38752167	20	+	27260156	EWS502	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.39232938278416596	[894]	[1043,1186,1343,1438]	7	hSpCas9	negative selection	6254338
38755156	38755179	20	-	27260156	EWS502	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.12224837605587253	[504]	[766,437,359,355]	-2	hSpCas9	negative selection	6254339
38750160	38750183	20	+	27260156	EWS502	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.09921463950120546	[392]	[305,495,354,401]	-2	hSpCas9	negative selection	6318620
38756006	38756029	20	-	27260156	EWS502	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.08144591755496955	[835]	[938,1018,1053,713]	1	hSpCas9	negative selection	6318621
38750160	38750183	20	-	27260156	EWS502	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.08463789284773571	[961]	[757,879,1192,1045]	-1	hSpCas9	negative selection	6318622
38752266	38752289	20	+	27260156	EW8	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.5305363777515586	[1256]	[542,927,652,686]	-7	hSpCas9	negative selection	6375588
38752144	38752167	20	+	27260156	EW8	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.2519977327046873	[894]	[927,794,816,926]	4	hSpCas9	negative selection	6375589
38755156	38755179	20	-	27260156	EW8	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.1277076815801857	[504]	[570,326,380,238]	-2	hSpCas9	negative selection	6375590
38750160	38750183	20	+	27260156	EW8	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.004865803928109924	[392]	[385,262,363,263]	0	hSpCas9	negative selection	6439871
38756006	38756029	20	-	27260156	EW8	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.13051630551226623	[835]	[869,642,548,451]	-2	hSpCas9	negative selection	6439872
38750160	38750183	20	-	27260156	EW8	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.18087794446035677	[961]	[1163,813,730,879]	3	hSpCas9	negative selection	6439873
38752266	38752289	20	+	27260156	CORL105	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.2647113135017063	[1256]	[1420,1109,1228,1148]	-5	hSpCas9	negative selection	6496839
38752144	38752167	20	+	27260156	CORL105	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	-0.00551849124375392	[894]	[968,892,1242,1100]	0	hSpCas9	negative selection	6496840
38755156	38755179	20	-	27260156	CORL105	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.4959326268152854	[504]	[437,367,448,427]	-7	hSpCas9	negative selection	6496841
38750160	38750183	20	+	27260156	CORL105	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.14692690088902505	[392]	[267,410,531,463]	-3	hSpCas9	negative selection	6561122
38756006	38756029	20	-	27260156	CORL105	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.16787583902908743	[835]	[1076,740,918,764]	-3	hSpCas9	negative selection	6561123
38750160	38750183	20	-	27260156	CORL105	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.02464163367843253	[961]	[1511,998,1080,995]	0	hSpCas9	negative selection	6561124
38752266	38752289	20	+	27260156	HS294T	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.48396231550923197	[1256]	[255,372,374,401]	-6	hSpCas9	negative selection	6618090
38752144	38752167	20	+	27260156	HS294T	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.9213166482177081	[894]	[498,460,586,1181]	9	hSpCas9	negative selection	6618091
38755156	38755179	20	-	27260156	HS294T	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	0.02238223879813954	[504]	[163,97,315,225]	0	hSpCas9	negative selection	6618092
38750160	38750183	20	+	27260156	HS294T	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.36487923860904503	[392]	[193,116,257,219]	5	hSpCas9	negative selection	6682373
38756006	38756029	20	-	27260156	HS294T	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.516211151172838	[835]	[207,173,242,292]	-6	hSpCas9	negative selection	6682374
38750160	38750183	20	-	27260156	HS294T	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.38136304483216144	[961]	[371,559,536,473]	5	hSpCas9	negative selection	6682375
38752266	38752289	20	+	27260156	HCC44	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.5463970354914041	[1256]	[1019,688,1611,727]	-7	hSpCas9	negative selection	6739341
38752144	38752167	20	+	27260156	HCC44	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.2505358421112692	[894]	[1081,1068,1631,1108]	4	hSpCas9	negative selection	6739342
38755156	38755179	20	-	27260156	HCC44	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.7789392079610788	[504]	[296,357,373,300]	-8	hSpCas9	negative selection	6739343
38750160	38750183	20	+	27260156	HCC44	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.21484606854225483	[392]	[719,408,644,346]	3	hSpCas9	negative selection	6803624
38756006	38756029	20	-	27260156	HCC44	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.05312861569058969	[835]	[1430,779,806,938]	0	hSpCas9	negative selection	6803625
38750160	38750183	20	-	27260156	HCC44	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.3347212812768331	[961]	[1059,644,1038,781]	-5	hSpCas9	negative selection	6803626
38752266	38752289	20	+	27260156	G402	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-1.110395274284531	[1256]	[755,836,680,584]	-8	hSpCas9	negative selection	6860592
38752144	38752167	20	+	27260156	G402	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.5198795105384374	[894]	[1453,1069,2304,1391]	6	hSpCas9	negative selection	6860593
38755156	38755179	20	-	27260156	G402	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-1.097325981161193	[504]	[200,275,316,340]	-8	hSpCas9	negative selection	6860594
38750160	38750183	20	+	27260156	G402	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.1265591566790727	[392]	[489,749,318,231]	-1	hSpCas9	negative selection	6924875
38756006	38756029	20	-	27260156	G402	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.6453725566744825	[835]	[949,651,624,432]	-7	hSpCas9	negative selection	6924876
38750160	38750183	20	-	27260156	G402	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.015784289180712285	[961]	[936,1258,1402,1020]	0	hSpCas9	negative selection	6924877
38752266	38752289	20	+	27260156	L33	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.1185711629246411	[1256]	[1103,491,747,1137]	-3	hSpCas9	negative selection	6981843
38752144	38752167	20	+	27260156	L33	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.3093758825104146	[894]	[1077,499,702,1020]	6	hSpCas9	negative selection	6981844
38755156	38755179	20	-	27260156	L33	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	0.19706184856072284	[504]	[629,180,336,704]	4	hSpCas9	negative selection	6981845
38750160	38750183	20	+	27260156	L33	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.06857135776700146	[392]	[320,181,242,497]	1	hSpCas9	negative selection	7046126
38756006	38756029	20	-	27260156	L33	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.09318427068911994	[835]	[923,380,589,774]	2	hSpCas9	negative selection	7046127
38750160	38750183	20	-	27260156	L33	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.09465422536700019	[961]	[1175,414,613,939]	2	hSpCas9	negative selection	7046128
38752266	38752289	20	+	27260156	K562	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.35737267033055087	[1256]	[541,842,1667,447]	-4	hSpCas9	negative selection	7103094
38752144	38752167	20	+	27260156	K562	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.9544826783980261	[894]	[1122,1350,2638,1050]	9	hSpCas9	negative selection	7103095
38755156	38755179	20	-	27260156	K562	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	0.5642565547676959	[504]	[562,892,667,541]	7	hSpCas9	negative selection	7103096
38750160	38750183	20	+	27260156	K562	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.19797189025751008	[392]	[612,303,473,238]	2	hSpCas9	negative selection	7167377
38756006	38756029	20	-	27260156	K562	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.40674183044498147	[835]	[863,737,255,427]	-5	hSpCas9	negative selection	7167378
38750160	38750183	20	-	27260156	K562	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.3391071281745568	[961]	[1267,772,765,1461]	4	hSpCas9	negative selection	7167379
38752266	38752289	20	+	27260156	HT29	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.27468244243880435	[1256]	[1148,1386,1307,1207]	-5	hSpCas9	negative selection	7224345
38752144	38752167	20	+	27260156	HT29	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.35258272402108004	[894]	[1415,1413,1629,1123]	7	hSpCas9	negative selection	7224346
38755156	38755179	20	-	27260156	HT29	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.2457669745003968	[504]	[648,581,461,403]	-5	hSpCas9	negative selection	7224347
38750160	38750183	20	+	27260156	HT29	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.07046454935192842	[392]	[476,438,518,389]	-1	hSpCas9	negative selection	7288628
38756006	38756029	20	-	27260156	HT29	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.1904080886445998	[835]	[1127,1731,865,973]	3	hSpCas9	negative selection	7288629
38750160	38750183	20	-	27260156	HT29	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.048796208570263566	[961]	[1039,1309,1101,1076]	-1	hSpCas9	negative selection	7288630
38752266	38752289	20	+	27260156	MHHES1	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.21922666925166268	[1256]	[1514,931,976,1378]	-4	hSpCas9	negative selection	7345596
38752144	38752167	20	+	27260156	MHHES1	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.33865562911804103	[894]	[1687,1283,1263,958]	6	hSpCas9	negative selection	7345597
38755156	38755179	20	-	27260156	MHHES1	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.2706151151733191	[504]	[581,638,349,359]	-5	hSpCas9	negative selection	7345598
38750160	38750183	20	+	27260156	MHHES1	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.2552268235069573	[392]	[448,391,234,401]	-5	hSpCas9	negative selection	7409879
38756006	38756029	20	-	27260156	MHHES1	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.18180107787867406	[835]	[1088,1259,882,1041]	3	hSpCas9	negative selection	7409880
38750160	38750183	20	-	27260156	MHHES1	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.2336657941156448	[961]	[1304,1549,1306,1000]	4	hSpCas9	negative selection	7409881
38752266	38752289	20	+	27260156	MEWO	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.17651553922521113	[1256]	[1120,1052,962]	-4	hSpCas9	negative selection	7466847
38752144	38752167	20	+	27260156	MEWO	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.11737518120174861	[894]	[1041,825,882]	2	hSpCas9	negative selection	7466848
38755156	38755179	20	-	27260156	MEWO	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.32443854949487405	[504]	[423,354,361]	-6	hSpCas9	negative selection	7466849
38750160	38750183	20	+	27260156	MEWO	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.05301906631250447	[392]	[457,398,225]	-1	hSpCas9	negative selection	7531130
38756006	38756029	20	-	27260156	MEWO	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.10347753486762257	[835]	[924,858,752]	2	hSpCas9	negative selection	7531131
38750160	38750183	20	-	27260156	MEWO	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.2886251071731488	[961]	[979,616,660]	-6	hSpCas9	negative selection	7531132
38752266	38752289	20	+	27260156	LNCAPCLONEFGC	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.6405126453122532	[1256]	[823,664,684,742]	-7	hSpCas9	negative selection	7588098
38752144	38752167	20	+	27260156	LNCAPCLONEFGC	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.34916255165790655	[894]	[1103,947,1096,994]	5	hSpCas9	negative selection	7588099
38755156	38755179	20	-	27260156	LNCAPCLONEFGC	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.5309922431434001	[504]	[304,356,304,294]	-7	hSpCas9	negative selection	7588100
38750160	38750183	20	+	27260156	LNCAPCLONEFGC	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.24463032578119753	[392]	[242,258,417,302]	-4	hSpCas9	negative selection	7652381
38756006	38756029	20	-	27260156	LNCAPCLONEFGC	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.06543636329968416	[835]	[802,676,784,639]	-1	hSpCas9	negative selection	7652382
38750160	38750183	20	-	27260156	LNCAPCLONEFGC	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.16960941196604729	[961]	[713,676,934,803]	-3	hSpCas9	negative selection	7652383
38752266	38752289	20	+	27260156	PANC0327	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.5924122234311247	[1256]	[521,692,698,1035]	-7	hSpCas9	negative selection	7709349
38752144	38752167	20	+	27260156	PANC0327	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.6817468300464925	[894]	[1072,1337,1671,993]	8	hSpCas9	negative selection	7709350
38755156	38755179	20	-	27260156	PANC0327	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.44014226146871543	[504]	[367,332,222,400]	-6	hSpCas9	negative selection	7709351
38750160	38750183	20	+	27260156	PANC0327	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.174021295787525	[392]	[259,303,197,471]	-3	hSpCas9	negative selection	7773632
38756006	38756029	20	-	27260156	PANC0327	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.11600056768744249	[835]	[661,575,726,787]	-2	hSpCas9	negative selection	7773633
38750160	38750183	20	-	27260156	PANC0327	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.2881054108601704	[961]	[1090,1183,903,979]	4	hSpCas9	negative selection	7773634
38752266	38752289	20	+	27260156	NCIH2009	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.12255875587601706	[1256]	[2250,1442,1271]	-2	hSpCas9	negative selection	7830600
38752144	38752167	20	+	27260156	NCIH2009	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.7680575590434185	[894]	[2504,1858,2099]	9	hSpCas9	negative selection	7830601
38755156	38755179	20	-	27260156	NCIH2009	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.06279322566494414	[504]	[835,791,426]	-1	hSpCas9	negative selection	7830602
38750160	38750183	20	+	27260156	NCIH2009	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.1455525733206619	[392]	[572,466,463]	-2	hSpCas9	negative selection	7894883
38756006	38756029	20	-	27260156	NCIH2009	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.18253209565166184	[835]	[1257,1089,781]	-3	hSpCas9	negative selection	7894884
38750160	38750183	20	-	27260156	NCIH2009	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.16559352048778364	[961]	[1596,1272,1671]	2	hSpCas9	negative selection	7894885
38752266	38752289	20	+	27260156	NCIH1373	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.9088168552099146	[1256]	[678,982,759,137]	-7	hSpCas9	negative selection	7951851
38752144	38752167	20	+	27260156	NCIH1373	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.5998160391280148	[894]	[2241,1010,1288,450]	6	hSpCas9	negative selection	7951852
38755156	38755179	20	-	27260156	NCIH1373	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-1.1882394493192048	[504]	[271,409,185,26]	-8	hSpCas9	negative selection	7951853
38750160	38750183	20	+	27260156	NCIH1373	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.5962026560771181	[392]	[275,162,366,97]	-5	hSpCas9	negative selection	8016134
38756006	38756029	20	-	27260156	NCIH1373	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.7015150448717813	[835]	[572,714,401,157]	-6	hSpCas9	negative selection	8016135
38750160	38750183	20	-	27260156	NCIH1373	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.8039126731357109	[961]	[1816,1016,2364,637]	7	hSpCas9	negative selection	8016136
38752266	38752289	20	+	27260156	PATU8902	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.4923730217386275	[1256]	[1294,1187,1063,1496]	-5	hSpCas9	negative selection	8073102
38752144	38752167	20	+	27260156	PATU8902	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.8484322271115544	[894]	[2791,2730,1498,2108]	8	hSpCas9	negative selection	8073103
38755156	38755179	20	-	27260156	PATU8902	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	0.06811539140714969	[504]	[590,1007,432,1027]	0	hSpCas9	negative selection	8073104
38750160	38750183	20	+	27260156	PATU8902	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.4126009808543105	[392]	[629,745,570,1040]	4	hSpCas9	negative selection	8137385
38756006	38756029	20	-	27260156	PATU8902	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.30338653583815	[835]	[1547,1639,866,1880]	3	hSpCas9	negative selection	8137386
38750160	38750183	20	-	27260156	PATU8902	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.2840364374910127	[961]	[1288,1457,1804,1957]	3	hSpCas9	negative selection	8137387
38752266	38752289	20	+	27260156	PANC1	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.7846817191301778	[1256]	[611,774,590,559]	-8	hSpCas9	negative selection	8194353
38752144	38752167	20	+	27260156	PANC1	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.3983782770248657	[894]	[1305,1036,897,823]	6	hSpCas9	negative selection	8194354
38755156	38755179	20	-	27260156	PANC1	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.1260533086266225	[504]	[325,376,571,319]	-2	hSpCas9	negative selection	8194355
38750160	38750183	20	+	27260156	PANC1	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.1667803808477336	[392]	[333,388,452,342]	2	hSpCas9	negative selection	8258636
38756006	38756029	20	-	27260156	PANC1	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.0895167766662629	[835]	[914,620,631,527]	-1	hSpCas9	negative selection	8258637
38750160	38750183	20	-	27260156	PANC1	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.037792087074848935	[961]	[715,1122,793,663]	0	hSpCas9	negative selection	8258638
38752266	38752289	20	+	27260156	PANC0813	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.9507103813226521	[1256]	[652,761,785,838]	-8	hSpCas9	negative selection	8315604
38752144	38752167	20	+	27260156	PANC0813	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.08373744749651835	[894]	[1449,1099,1140,811]	1	hSpCas9	negative selection	8315605
38755156	38755179	20	-	27260156	PANC0813	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-1.3446947153735223	[504]	[347,192,286,122]	-9	hSpCas9	negative selection	8315606
38750160	38750183	20	+	27260156	PANC0813	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.5443369256450279	[392]	[374,206,365,322]	-7	hSpCas9	negative selection	8379887
38756006	38756029	20	-	27260156	PANC0813	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-1.249090695522089	[835]	[425,363,393,465]	-9	hSpCas9	negative selection	8379888
38750160	38750183	20	-	27260156	PANC0813	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.047297942985421226	[961]	[1240,1192,962,993]	-1	hSpCas9	negative selection	8379889
38752266	38752289	20	+	27260156	RDES	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.4169684659650652	[1256]	[825,964,1175,1460]	-6	hSpCas9	negative selection	8436855
38752144	38752167	20	+	27260156	RDES	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.41128873060124127	[894]	[1389,1188,1333,1554]	6	hSpCas9	negative selection	8436856
38755156	38755179	20	-	27260156	RDES	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.5238300655375139	[504]	[440,268,416,493]	-7	hSpCas9	negative selection	8436857
38750160	38750183	20	+	27260156	RDES	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.12744518093697896	[392]	[437,375,565,625]	2	hSpCas9	negative selection	8501138
38756006	38756029	20	-	27260156	RDES	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.28556011839735496	[835]	[653,665,869,1020]	-5	hSpCas9	negative selection	8501139
38750160	38750183	20	-	27260156	RDES	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.0754236274587462	[961]	[768,981,1138,1404]	-1	hSpCas9	negative selection	8501140
38752266	38752289	20	+	27260156	PC3	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.20627258159017403	[1256]	[822,1021,1526,1138]	-5	hSpCas9	negative selection	8558106
38752144	38752167	20	+	27260156	PC3	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.11308804110442894	[894]	[618,1054,1606,873]	2	hSpCas9	negative selection	8558107
38755156	38755179	20	-	27260156	PC3	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.28019557354291735	[504]	[297,489,651,305]	-6	hSpCas9	negative selection	8558108
38750160	38750183	20	+	27260156	PC3	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.1918375952065952	[392]	[269,371,988,408]	4	hSpCas9	negative selection	8622389
38756006	38756029	20	-	27260156	PC3	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.05081467850625088	[835]	[539,767,1321,824]	-1	hSpCas9	negative selection	8622390
38750160	38750183	20	-	27260156	PC3	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.24988727135829358	[961]	[557,706,1361,845]	-5	hSpCas9	negative selection	8622391
38752266	38752289	20	+	27260156	PATU8988T	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.6552067160692284	[1256]	[688,945,640,831]	-7	hSpCas9	negative selection	8679357
38752144	38752167	20	+	27260156	PATU8988T	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.1657111182928196	[894]	[1052,1013,907,904]	3	hSpCas9	negative selection	8679358
38755156	38755179	20	-	27260156	PATU8988T	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	0.22146746797693984	[504]	[448,981,325,559]	4	hSpCas9	negative selection	8679359
38750160	38750183	20	+	27260156	PATU8988T	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.16281380753934582	[392]	[298,373,288,403]	-3	hSpCas9	negative selection	8743640
38756006	38756029	20	-	27260156	PATU8988T	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.13009635390989882	[835]	[507,764,864,821]	-2	hSpCas9	negative selection	8743641
38750160	38750183	20	-	27260156	PATU8988T	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.06611770019298469	[961]	[776,837,853,1094]	-1	hSpCas9	negative selection	8743642
38752266	38752289	20	+	27260156	T47D	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.3251127738594919	[1256]	[1245,1092,1278,1058]	-6	hSpCas9	negative selection	8800608
38752144	38752167	20	+	27260156	T47D	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.2557293029937645	[894]	[1223,1099,1213,1460]	5	hSpCas9	negative selection	8800609
38755156	38755179	20	-	27260156	T47D	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.3772786812297656	[504]	[479,441,435,454]	-7	hSpCas9	negative selection	8800610
38750160	38750183	20	+	27260156	T47D	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.08001861951218928	[392]	[520,537,461,407]	1	hSpCas9	negative selection	8864891
38756006	38756029	20	-	27260156	T47D	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.245088989982447	[835]	[884,858,666,876]	-5	hSpCas9	negative selection	8864892
38750160	38750183	20	-	27260156	T47D	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.10857590440340426	[961]	[1157,1032,935,1032]	-2	hSpCas9	negative selection	8864893
38752266	38752289	20	+	27260156	SU8686	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.6236389850994268	[1256]	[668,767,756,1102]	-7	hSpCas9	negative selection	8921859
38752144	38752167	20	+	27260156	SU8686	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.4840295902204531	[894]	[1039,1133,1309,1561]	7	hSpCas9	negative selection	8921860
38755156	38755179	20	-	27260156	SU8686	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.1819833260577004	[504]	[402,425,499,440]	-3	hSpCas9	negative selection	8921861
38750160	38750183	20	+	27260156	SU8686	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.1291659939047797	[392]	[410,394,410,501]	2	hSpCas9	negative selection	8986142
38756006	38756029	20	-	27260156	SU8686	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.05573420558932707	[835]	[703,777,742,1003]	-1	hSpCas9	negative selection	8986143
38750160	38750183	20	-	27260156	SU8686	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.20796687405453884	[961]	[915,1063,1320,1134]	3	hSpCas9	negative selection	8986144
38752266	38752289	20	+	27260156	SKES1	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.08112293755303934	[1256]	[1374,1258,1050,1091]	-2	hSpCas9	negative selection	9043110
38752144	38752167	20	+	27260156	SKES1	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.23531603664602818	[894]	[1267,1197,885,907]	5	hSpCas9	negative selection	9043111
38755156	38755179	20	-	27260156	SKES1	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.1388164083524689	[504]	[454,506,489,386]	-3	hSpCas9	negative selection	9043112
38750160	38750183	20	+	27260156	SKES1	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.16921035820632457	[392]	[334,433,301,330]	-4	hSpCas9	negative selection	9107393
38756006	38756029	20	-	27260156	SKES1	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.086905842990328	[835]	[1046,829,528,772]	-2	hSpCas9	negative selection	9107394
38750160	38750183	20	-	27260156	SKES1	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.1325567306433919	[961]	[1017,807,825,854]	-3	hSpCas9	negative selection	9107395
38752266	38752289	20	+	27260156	TOV112D	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.4783288642986425	[1256]	[931,1354,655,786]	-7	hSpCas9	negative selection	9164361
38752144	38752167	20	+	27260156	TOV112D	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.04414786780184532	[894]	[1065,1119,842,731]	0	hSpCas9	negative selection	9164362
38755156	38755179	20	-	27260156	TOV112D	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.5053064807728455	[504]	[305,504,286,358]	-7	hSpCas9	negative selection	9164363
38750160	38750183	20	+	27260156	TOV112D	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.04449882609260114	[392]	[379,476,516,180]	-1	hSpCas9	negative selection	9228644
38756006	38756029	20	-	27260156	TOV112D	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	-0.4978405856697638	[835]	[603,765,439,603]	-7	hSpCas9	negative selection	9228645
38750160	38750183	20	-	27260156	TOV112D	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.24627698442553714	[961]	[849,865,800,748]	-5	hSpCas9	negative selection	9228646
38752266	38752289	20	+	27260156	TC71	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.332166652408421	[1256]	[1311,881,989,1095]	-7	hSpCas9	negative selection	9285612
38752144	38752167	20	+	27260156	TC71	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.23852926721194068	[894]	[1204,1110,974,1246]	6	hSpCas9	negative selection	9285613
38755156	38755179	20	-	27260156	TC71	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.01637236733725661	[504]	[516,588,464,574]	0	hSpCas9	negative selection	9285614
38750160	38750183	20	+	27260156	TC71	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	-0.03649750730513707	[392]	[361,409,473,394]	-1	hSpCas9	negative selection	9349895
38756006	38756029	20	-	27260156	TC71	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.09742189874352325	[835]	[856,965,943,1077]	2	hSpCas9	negative selection	9349896
38750160	38750183	20	-	27260156	TC71	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	-0.07916451047344863	[961]	[836,990,1094,980]	-2	hSpCas9	negative selection	9349897
38752266	38752289	20	+	27260156	TC32	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.24038829504638604	[1256]	[893,637,1516,1142]	-4	hSpCas9	negative selection	9406863
38752144	38752167	20	+	27260156	TC32	viability	AACTGCAAGCGCATCAATCTTGG	ACTR5	ENSG00000101442	0.4832016891819505	[894]	[901,864,1560,1547]	7	hSpCas9	negative selection	9406864
38755156	38755179	20	-	27260156	TC32	viability	TTACCTGCACATATAGCAGTCGG	ACTR5	ENSG00000101442	-0.22651457905311956	[504]	[377,285,511,494]	-4	hSpCas9	negative selection	9406865
38750160	38750183	20	+	27260156	TC32	viability	CCAAAGAACTCGATGTGCAGTGG	ACTR5	ENSG00000101442	0.0037626941729436147	[392]	[287,280,509,453]	0	hSpCas9	negative selection	9471146
38756006	38756029	20	-	27260156	TC32	viability	TGTCTACCACATCCACCTCGAGG	ACTR5	ENSG00000101442	0.032262199983528195	[835]	[1002,515,820,916]	0	hSpCas9	negative selection	9471147
38750160	38750183	20	-	27260156	TC32	viability	CCACTGCACATCGAGTTCTTTGG	ACTR5	ENSG00000101442	0.03527071147643146	[961]	[952,690,1230,911]	0	hSpCas9	negative selection	9471148
38748570	38748593	20	+	27869803	HPAFII	viability after 27 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.5962217332117348	[442]	[374,332,NaN]	5	hSpCas9	negative selection	9577533
38750093	38750116	20	+	27869803	HPAFII	viability after 27 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.5416321850541791	[147]	[23,77,NaN]	-4	hSpCas9	negative selection	9577534
38752198	38752221	20	+	27869803	HPAFII	viability after 27 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	0.24218729163567576	[800]	[526,473,NaN]	2	hSpCas9	negative selection	9577535
38755098	38755121	20	+	27869803	HPAFII	viability after 27 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.7822381138847032	[202]	[386,13,NaN]	6	hSpCas9	negative selection	9577536
38755859	38755882	20	+	27869803	HPAFII	viability after 27 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	0.1749524593943601	[86]	[61,42,NaN]	1	hSpCas9	negative selection	9577537
38766322	38766345	20	+	27869803	HPAFII	viability after 27 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-1.0167253405762406	[260]	[45,85,NaN]	-6	hSpCas9	negative selection	9577538
38748570	38748593	20	+	27869803	HPAFII	viability after 15 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.4866388706909357	[442]	[922,507,NaN]	5	hSpCas9	negative selection	9659982
38750093	38750116	20	+	27869803	HPAFII	viability after 15 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.9201092081487195	[147]	[170,29,NaN]	-7	hSpCas9	negative selection	9659983
38752198	38752221	20	+	27869803	HPAFII	viability after 15 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	0.0273408093192562	[800]	[1176,690,NaN]	0	hSpCas9	negative selection	9659984
38755098	38755121	20	+	27869803	HPAFII	viability after 15 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.519062710334874	[202]	[414,248,NaN]	6	hSpCas9	negative selection	9659985
38755859	38755882	20	+	27869803	HPAFII	viability after 15 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	0.6662165029409022	[86]	[267,73,NaN]	7	hSpCas9	negative selection	9659986
38766322	38766345	20	+	27869803	HPAFII	viability after 15 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.8588507991871968	[260]	[166,146,NaN]	-7	hSpCas9	negative selection	9659987
38748570	38748593	20	+	27869803	ASPC1	viability after 36 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	-0.4198737455632875	[1403]	[196,435,425]	-4	hSpCas9	negative selection	9742431
38750093	38750116	20	+	27869803	ASPC1	viability after 36 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.0017094459782027727	[314]	[262,31,62]	0	hSpCas9	negative selection	9742432
38752198	38752221	20	+	27869803	ASPC1	viability after 36 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.195439286812221	[2135]	[1077,490,471]	-2	hSpCas9	negative selection	9742433
38755098	38755121	20	+	27869803	ASPC1	viability after 36 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	-0.19528975562567907	[588]	[192,223,132]	-2	hSpCas9	negative selection	9742434
38755859	38755882	20	+	27869803	ASPC1	viability after 36 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	-1.488714492966462	[245]	[0,75,14]	-8	hSpCas9	negative selection	9742435
38766322	38766345	20	+	27869803	ASPC1	viability after 36 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	1.7956960776405118	[609]	[442,1720,159]	9	hSpCas9	negative selection	9742436
38748570	38748593	20	+	27869803	PATU8988S	viability after 35 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	-0.22057553486343762	[961]	[338,325,NaN]	-2	hSpCas9	negative selection	9824880
38750093	38750116	20	+	27869803	PATU8988S	viability after 35 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.1198074409883432	[339]	[67,57,NaN]	-8	hSpCas9	negative selection	9824881
38752198	38752221	20	+	27869803	PATU8988S	viability after 35 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.6807929362232045	[1649]	[437,390,NaN]	-6	hSpCas9	negative selection	9824882
38755098	38755121	20	+	27869803	PATU8988S	viability after 35 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.4864190586542003	[520]	[279,307,NaN]	5	hSpCas9	negative selection	9824883
38755859	38755882	20	+	27869803	PATU8988S	viability after 35 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	0.4303052250551699	[210]	[119,108,NaN]	5	hSpCas9	negative selection	9824884
38766322	38766345	20	+	27869803	PATU8988S	viability after 35 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	0.04954059102918007	[504]	[207,212,NaN]	0	hSpCas9	negative selection	9824885
38748570	38748593	20	+	27869803	PATU8988S	viability after 31 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	-0.06745792999171862	[961]	[307,439,NaN]	0	hSpCas9	negative selection	9907329
38750093	38750116	20	+	27869803	PATU8988S	viability after 31 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-0.6499416194145851	[339]	[92,77,NaN]	-6	hSpCas9	negative selection	9907330
38752198	38752221	20	+	27869803	PATU8988S	viability after 31 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	-0.4189561327432656	[1649]	[426,574,NaN]	-5	hSpCas9	negative selection	9907331
38755098	38755121	20	+	27869803	PATU8988S	viability after 31 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.17068540748848549	[520]	[217,253,NaN]	2	hSpCas9	negative selection	9907332
38755859	38755882	20	+	27869803	PATU8988S	viability after 31 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	0.3079451403951097	[210]	[75,139,NaN]	4	hSpCas9	negative selection	9907333
38766322	38766345	20	+	27869803	PATU8988S	viability after 31 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.2811182182318228	[504]	[137,200,NaN]	-3	hSpCas9	negative selection	9907334
38748570	38748593	20	+	27869803	HPAFII	viability after 35 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.9183349686209297	[442]	[476,363,NaN]	6	hSpCas9	negative selection	9989778
38750093	38750116	20	+	27869803	HPAFII	viability after 35 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.2508997409139124	[147]	[54,4,NaN]	-6	hSpCas9	negative selection	9989779
38752198	38752221	20	+	27869803	HPAFII	viability after 35 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	0.09524583681145238	[800]	[197,697,NaN]	0	hSpCas9	negative selection	9989780
38755098	38755121	20	+	27869803	HPAFII	viability after 35 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	1.8320785009119582	[202]	[649,45,NaN]	9	hSpCas9	negative selection	9989781
38755859	38755882	20	+	27869803	HPAFII	viability after 35 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	1.593998680661409	[86]	[171,88,NaN]	9	hSpCas9	negative selection	9989782
38766322	38766345	20	+	27869803	HPAFII	viability after 35 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-0.3116165735410615	[260]	[89,124,NaN]	-2	hSpCas9	negative selection	9989783
38748570	38748593	20	+	27869803	HPAFII	viability after 31 days	TACCGCTGGTGCTGGACAACGGG	ACTR5	ENSG00000101442	0.5322282495909598	[442]	[326,394,NaN]	4	hSpCas9	negative selection	10072227
38750093	38750116	20	+	27869803	HPAFII	viability after 31 days	TGAGTGCTACGGGATTCCCAAGG	ACTR5	ENSG00000101442	-1.0017878641959692	[147]	[40,41,NaN]	-6	hSpCas9	negative selection	10072228
38752198	38752221	20	+	27869803	HPAFII	viability after 31 days	CTCCTCCAGCTGAAGTACCCTGG	ACTR5	ENSG00000101442	0.1731684704693568	[800]	[447,570,NaN]	1	hSpCas9	negative selection	10072229
38755098	38755121	20	+	27869803	HPAFII	viability after 31 days	AGGAGCTCAATGCCCGGCGGCGG	ACTR5	ENSG00000101442	0.645909168026906	[202]	[239,110,NaN]	5	hSpCas9	negative selection	10072230
38755859	38755882	20	+	27869803	HPAFII	viability after 31 days	ACTTCTAGAGGATGGCCAGATGG	ACTR5	ENSG00000101442	1.2884459790752867	[86]	[180,51,NaN]	8	hSpCas9	negative selection	10072231
38766322	38766345	20	+	27869803	HPAFII	viability after 31 days	CTCATAGGAGAAGAACAGGCTGG	ACTR5	ENSG00000101442	-1.0624574260736737	[260]	[61,78,NaN]	-6	hSpCas9	negative selection	10072232
38748590	38748613	20	+	28162770	P31FUJ	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-1.4122860342815355	[264]	[116]	-7	hSpCas9	negative selection	10106552
38765508	38765531	20	-	28162770	P31FUJ	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.0818578900089445	[397]	[494]	0	hSpCas9	negative selection	10106553
38748732	38748755	20	+	28162770	P31FUJ	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-1.9639854459865789	[82]	[24]	-8	hSpCas9	negative selection	10106554
38748743	38748766	20	-	28162770	P31FUJ	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	0.222877279361811	[34]	[47]	2	hSpCas9	negative selection	10106555
38752188	38752211	20	-	28162770	P31FUJ	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-2.412125903858941	[76]	[16]	-8	hSpCas9	negative selection	10106556
38752266	38752289	20	+	28162770	P31FUJ	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-1.0124121359890783	[205]	[119]	-6	hSpCas9	negative selection	10106557
38755071	38755094	20	+	28162770	P31FUJ	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.4499003260813134	[271]	[233]	-4	hSpCas9	negative selection	10106558
38755946	38755969	20	+	28162770	P31FUJ	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.7779244406037438	[374]	[256]	-6	hSpCas9	negative selection	10106559
38755994	38756017	20	+	28162770	P31FUJ	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-1.3583330864982375	[23]	[10]	-7	hSpCas9	negative selection	10106560
38765465	38765488	20	-	28162770	P31FUJ	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	-3.554730299301741	[9]	[0]	-9	hSpCas9	negative selection	10106561
38748590	38748613	20	+	28162770	TF1	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10275918
38765508	38765531	20	-	28162770	TF1	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	NaN	[NaN]	[304]	1	hSpCas9	negative selection	10275919
38748732	38748755	20	+	28162770	TF1	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10275920
38748743	38748766	20	-	28162770	TF1	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10275921
38752188	38752211	20	-	28162770	TF1	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10275922
38752266	38752289	20	+	28162770	TF1	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10275923
38755071	38755094	20	+	28162770	TF1	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10275924
38755946	38755969	20	+	28162770	TF1	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10275925
38755994	38756017	20	+	28162770	TF1	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10275926
38765465	38765488	20	-	28162770	TF1	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10275927
38748590	38748613	20	+	28162770	SKM1	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.1439297929093679	[54]	[87]	-1	hSpCas9	negative selection	10445284
38765508	38765531	20	-	28162770	SKM1	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.052467419894135614	[77]	[142]	0	hSpCas9	negative selection	10445285
38748732	38748755	20	+	28162770	SKM1	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-3.880895387075574	[24]	[2]	-9	hSpCas9	negative selection	10445286
38748743	38748766	20	-	28162770	SKM1	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-0.8220016980220053	[11]	[11]	-6	hSpCas9	negative selection	10445287
38752188	38752211	20	-	28162770	SKM1	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-5.2143191208007655	[20]	[0]	-9	hSpCas9	negative selection	10445288
38752266	38752289	20	+	28162770	SKM1	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-1.2564045221677804	[49]	[36]	-7	hSpCas9	negative selection	10445289
38755071	38755094	20	+	28162770	SKM1	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.30065529659682094	[84]	[121]	-3	hSpCas9	negative selection	10445290
38755946	38755969	20	+	28162770	SKM1	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.2587342684001683	[66]	[98]	-2	hSpCas9	negative selection	10445291
38755994	38756017	20	+	28162770	SKM1	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	1.1779983019779943	[4]	[19]	9	hSpCas9	negative selection	10445292
38765465	38765488	20	-	28162770	SKM1	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	0.4999263968653569	[1]	[4]	5	hSpCas9	negative selection	10445293
38748590	38748613	20	+	28162770	SKM1	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.1439297929093679	[54]	[87]	-1	hSpCas9	negative selection	10614650
38765508	38765531	20	-	28162770	SKM1	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.052467419894135614	[77]	[142]	0	hSpCas9	negative selection	10614651
38748732	38748755	20	+	28162770	SKM1	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-3.880895387075574	[24]	[2]	-9	hSpCas9	negative selection	10614652
38748743	38748766	20	-	28162770	SKM1	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-0.8220016980220053	[11]	[11]	-6	hSpCas9	negative selection	10614653
38752188	38752211	20	-	28162770	SKM1	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-5.2143191208007655	[20]	[0]	-9	hSpCas9	negative selection	10614654
38752266	38752289	20	+	28162770	SKM1	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-1.2564045221677804	[49]	[36]	-7	hSpCas9	negative selection	10614655
38755071	38755094	20	+	28162770	SKM1	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.30065529659682094	[84]	[121]	-3	hSpCas9	negative selection	10614656
38755946	38755969	20	+	28162770	SKM1	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.2587342684001683	[66]	[98]	-2	hSpCas9	negative selection	10614657
38755994	38756017	20	+	28162770	SKM1	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	1.1779983019779943	[4]	[19]	9	hSpCas9	negative selection	10614658
38765465	38765488	20	-	28162770	SKM1	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	0.4999263968653569	[1]	[4]	5	hSpCas9	negative selection	10614659
38748590	38748613	20	+	28162770	PL21	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.5941117202941036	[273]	[78]	-4	hSpCas9	negative selection	10784016
38765508	38765531	20	-	28162770	PL21	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	-0.4510131659263027	[222]	[70]	-3	hSpCas9	negative selection	10784017
38748732	38748755	20	+	28162770	PL21	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-1.481684425484425	[76]	[11]	-7	hSpCas9	negative selection	10784018
38748743	38748766	20	-	28162770	PL21	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-3.443716575285405	[24]	[0]	-9	hSpCas9	negative selection	10784019
38752188	38752211	20	-	28162770	PL21	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-0.9842849566481071	[49]	[10]	-6	hSpCas9	negative selection	10784020
38752266	38752289	20	+	28162770	PL21	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.060387935733899	[229]	[95]	0	hSpCas9	negative selection	10784021
38755071	38755094	20	+	28162770	PL21	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-1.7504723585485162	[200]	[25]	-8	hSpCas9	negative selection	10784022
38755946	38755969	20	+	28162770	PL21	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	0.6795677010381188	[240]	[167]	6	hSpCas9	negative selection	10784023
38755994	38756017	20	+	28162770	PL21	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-1.7998603855106805	[15]	[1]	-8	hSpCas9	negative selection	10784024
38765465	38765488	20	-	28162770	PL21	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	-1.6072153075682847	[6]	[0]	-8	hSpCas9	negative selection	10784025
38748590	38748613	20	+	28162770	P31FUJ	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-1.4122860342815355	[264]	[116]	-7	hSpCas9	negative selection	10953382
38765508	38765531	20	-	28162770	P31FUJ	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.0818578900089445	[397]	[494]	0	hSpCas9	negative selection	10953383
38748732	38748755	20	+	28162770	P31FUJ	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-1.9639854459865789	[82]	[24]	-8	hSpCas9	negative selection	10953384
38748743	38748766	20	-	28162770	P31FUJ	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	0.222877279361811	[34]	[47]	2	hSpCas9	negative selection	10953385
38752188	38752211	20	-	28162770	P31FUJ	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-2.412125903858941	[76]	[16]	-8	hSpCas9	negative selection	10953386
38752266	38752289	20	+	28162770	P31FUJ	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-1.0124121359890783	[205]	[119]	-6	hSpCas9	negative selection	10953387
38755071	38755094	20	+	28162770	P31FUJ	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.4499003260813134	[271]	[233]	-4	hSpCas9	negative selection	10953388
38755946	38755969	20	+	28162770	P31FUJ	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.7779244406037438	[374]	[256]	-6	hSpCas9	negative selection	10953389
38755994	38756017	20	+	28162770	P31FUJ	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-1.3583330864982375	[23]	[10]	-7	hSpCas9	negative selection	10953390
38765465	38765488	20	-	28162770	P31FUJ	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	-3.554730299301741	[9]	[0]	-9	hSpCas9	negative selection	10953391
38748590	38748613	20	+	28162770	OCIAML5	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.2713660969970003	[112]	[168]	-2	hSpCas9	negative selection	11122748
38765508	38765531	20	-	28162770	OCIAML5	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.18143034112409018	[148]	[304]	1	hSpCas9	negative selection	11122749
38748732	38748755	20	+	28162770	OCIAML5	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-6.758957166472515	[59]	[0]	-9	hSpCas9	negative selection	11122750
38748743	38748766	20	-	28162770	OCIAML5	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-0.9775974529478559	[11]	[10]	-6	hSpCas9	negative selection	11122751
38752188	38752211	20	-	28162770	OCIAML5	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-3.3114981895012945	[21]	[3]	-9	hSpCas9	negative selection	11122752
38752266	38752289	20	+	28162770	OCIAML5	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-1.5852800301690955	[127]	[76]	-7	hSpCas9	negative selection	11122753
38755071	38755094	20	+	28162770	OCIAML5	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.4401687791157203	[114]	[152]	-3	hSpCas9	negative selection	11122754
38755946	38755969	20	+	28162770	OCIAML5	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	0.0800293646341994	[173]	[331]	0	hSpCas9	negative selection	11122755
38755994	38756017	20	+	28162770	OCIAML5	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	2.0354586998775908	[4]	[36]	9	hSpCas9	negative selection	11122756
38765465	38765488	20	-	28162770	OCIAML5	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	-2.4370290715851537	[2]	[0]	-8	hSpCas9	negative selection	11122757
38748590	38748613	20	+	28162770	EOL1	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	0.1039570223562365	[437]	[247]	0	hSpCas9	negative selection	11292114
38765508	38765531	20	-	28162770	EOL1	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	-0.6315598664784364	[296]	[100]	-4	hSpCas9	negative selection	11292115
38748732	38748755	20	+	28162770	EOL1	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-1.9558706126767929	[161]	[21]	-8	hSpCas9	negative selection	11292116
38748743	38748766	20	-	28162770	EOL1	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-0.6604147291506219	[71]	[23]	-5	hSpCas9	negative selection	11292117
38752188	38752211	20	-	28162770	EOL1	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-1.3042709189253465	[149]	[31]	-7	hSpCas9	negative selection	11292118
38752266	38752289	20	+	28162770	EOL1	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.8812085962615922	[450]	[128]	-6	hSpCas9	negative selection	11292119
38755071	38755094	20	+	28162770	EOL1	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.2286984887251475	[257]	[115]	-2	hSpCas9	negative selection	11292120
38755946	38755969	20	+	28162770	EOL1	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	0.26282807186534046	[385]	[243]	2	hSpCas9	negative selection	11292121
38755994	38756017	20	+	28162770	EOL1	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-2.7758919465705576	[12]	[0]	-9	hSpCas9	negative selection	11292122
38765465	38765488	20	-	28162770	EOL1	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	2.9640761357571717	[8]	[36]	9	hSpCas9	negative selection	11292123
38748590	38748613	20	+	28162770	MOLM13	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-1.0823077010159006	[368]	[125]	-5	hSpCas9	negative selection	11461480
38765508	38765531	20	-	28162770	MOLM13	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.34503263375904525	[342]	[314]	2	hSpCas9	negative selection	11461481
38748732	38748755	20	+	28162770	MOLM13	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-5.497894903117508	[124]	[1]	-9	hSpCas9	negative selection	11461482
38748743	38748766	20	-	28162770	MOLM13	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-1.7647713752456964	[93]	[19]	-7	hSpCas9	negative selection	11461483
38752188	38752211	20	-	28162770	MOLM13	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-6.1170731191765775	[95]	[0]	-9	hSpCas9	negative selection	11461484
38752266	38752289	20	+	28162770	MOLM13	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-1.786351905831209	[228]	[47]	-7	hSpCas9	negative selection	11461485
38755071	38755094	20	+	28162770	MOLM13	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	0.020430404573357507	[284]	[208]	0	hSpCas9	negative selection	11461486
38755946	38755969	20	+	28162770	MOLM13	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.6642665770219875	[376]	[171]	-4	hSpCas9	negative selection	11461487
38755994	38756017	20	+	28162770	MOLM13	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	0.2699500039326703	[38]	[33]	2	hSpCas9	negative selection	11461488
38765465	38765488	20	-	28162770	MOLM13	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	-3.232550336596514	[12]	[0]	-8	hSpCas9	negative selection	11461489
38748590	38748613	20	+	28162770	HEL	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-1.0555232328353652	[330]	[101]	-6	hSpCas9	negative selection	11630846
38765508	38765531	20	-	28162770	HEL	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	-0.05115804027396348	[274]	[169]	0	hSpCas9	negative selection	11630847
38748732	38748755	20	+	28162770	HEL	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-2.333013621752966	[117]	[14]	-8	hSpCas9	negative selection	11630848
38748743	38748766	20	-	28162770	HEL	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-0.8845081708645117	[48]	[16]	-5	hSpCas9	negative selection	11630849
38752188	38752211	20	-	28162770	HEL	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-4.783525922701741	[85]	[1]	-9	hSpCas9	negative selection	11630850
38752266	38752289	20	+	28162770	HEL	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-3.856493794694915	[293]	[12]	-9	hSpCas9	negative selection	11630851
38755071	38755094	20	+	28162770	HEL	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-1.5863951672151462	[285]	[60]	-7	hSpCas9	negative selection	11630852
38755946	38755969	20	+	28162770	HEL	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-1.194989739100766	[335]	[93]	-6	hSpCas9	negative selection	11630853
38755994	38756017	20	+	28162770	HEL	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-4.81669278663694	[43]	[0]	-9	hSpCas9	negative selection	11630854
38765465	38765488	20	-	28162770	HEL	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	-2.6791892628870055	[9]	[0]	-8	hSpCas9	negative selection	11630855
38748590	38748613	20	+	28162770	MV411	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.834200918241582	[308]	[145]	-5	hSpCas9	negative selection	11800212
38765508	38765531	20	-	28162770	MV411	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.09485979290435975	[278]	[250]	0	hSpCas9	negative selection	11800213
38748732	38748755	20	+	28162770	MV411	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-2.678561867773448	[151]	[19]	-9	hSpCas9	negative selection	11800214
38748743	38748766	20	-	28162770	MV411	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-0.015596855051018377	[29]	[24]	0	hSpCas9	negative selection	11800215
38752188	38752211	20	-	28162770	MV411	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-5.074490544104587	[39]	[0]	-9	hSpCas9	negative selection	11800216
38752266	38752289	20	+	28162770	MV411	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.8885401187361994	[188]	[85]	-6	hSpCas9	negative selection	11800217
38755071	38755094	20	+	28162770	MV411	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.09466842604221734	[179]	[141]	0	hSpCas9	negative selection	11800218
38755946	38755969	20	+	28162770	MV411	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.42558112660357683	[227]	[142]	-3	hSpCas9	negative selection	11800219
38755994	38756017	20	+	28162770	MV411	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-2.074490544104587	[4]	[0]	-8	hSpCas9	negative selection	11800220
38765465	38765488	20	-	28162770	MV411	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	-0.48952804338343103	[4]	[2]	-4	hSpCas9	negative selection	11800221
38748590	38748613	20	+	28162770	MONOMAC1	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-1.0494796586456958	[129]	[71]	-7	hSpCas9	negative selection	11969578
38765508	38765531	20	-	28162770	MONOMAC1	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	-0.1045247082700155	[150]	[160]	-1	hSpCas9	negative selection	11969579
38748732	38748755	20	+	28162770	MONOMAC1	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-1.5380737648946208	[37]	[14]	-8	hSpCas9	negative selection	11969580
38748743	38748766	20	-	28162770	MONOMAC1	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-0.405623468870971	[51]	[44]	-4	hSpCas9	negative selection	11969581
38752188	38752211	20	-	28162770	MONOMAC1	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-0.5531806572848292	[31]	[24]	-5	hSpCas9	negative selection	11969582
38752266	38752289	20	+	28162770	MONOMAC1	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-2.047460491009044	[118]	[32]	-9	hSpCas9	negative selection	11969583
38755071	38755094	20	+	28162770	MONOMAC1	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-1.5731853329448027	[121]	[46]	-8	hSpCas9	negative selection	11969584
38755946	38755969	20	+	28162770	MONOMAC1	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-2.324148764962893	[165]	[37]	-9	hSpCas9	negative selection	11969585
38755994	38756017	20	+	28162770	MONOMAC1	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-3.897476565200646	[12]	[0]	-9	hSpCas9	negative selection	11969586
38765465	38765488	20	-	28162770	MONOMAC1	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	2.610318074998051	[0]	[6]	9	hSpCas9	negative selection	11969587
38748590	38748613	20	+	28162770	OCIAML2	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.2347415614214901	[37]	[178]	-2	hSpCas9	negative selection	12138944
38765508	38765531	20	-	28162770	OCIAML2	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	0.4579558414656764	[43]	[334]	4	hSpCas9	negative selection	12138945
38748732	38748755	20	+	28162770	OCIAML2	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-3.011198206604864	[15]	[10]	-9	hSpCas9	negative selection	12138946
38748743	38748766	20	-	28162770	OCIAML2	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-2.2075954194083676	[9]	[11]	-8	hSpCas9	negative selection	12138947
38752188	38752211	20	-	28162770	OCIAML2	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-3.570165498793076	[14]	[6]	-9	hSpCas9	negative selection	12138948
38752266	38752289	20	+	28162770	OCIAML2	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-0.8994731240460355	[34]	[103]	-6	hSpCas9	negative selection	12138949
38755071	38755094	20	+	28162770	OCIAML2	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.7139009762545252	[28]	[97]	-5	hSpCas9	negative selection	12138950
38755946	38755969	20	+	28162770	OCIAML2	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.44025617619864227	[46]	[191]	-3	hSpCas9	negative selection	12138951
38755994	38756017	20	+	28162770	OCIAML2	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-3.0555923259633175	[2]	[1]	-9	hSpCas9	negative selection	12138952
38765465	38765488	20	-	28162770	OCIAML2	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	0.7388235403867882	[3]	[36]	7	hSpCas9	negative selection	12138953
38748590	38748613	20	+	28162770	OCIAML3	viability	GGGTCGTTCCAAGTCCGCGCTGG	ACTR5	ENSG00000101442	-0.38311085782554466	[53]	[124]	-3	hSpCas9	negative selection	12308310
38765508	38765531	20	-	28162770	OCIAML3	viability	TAGAAGTCAAACCTGAACAGTGG	ACTR5	ENSG00000101442	-0.14104068541299725	[60]	[166]	-1	hSpCas9	negative selection	12308311
38748732	38748755	20	+	28162770	OCIAML3	viability	GCAGCCTGGAGCCACTGCGCTGG	ACTR5	ENSG00000101442	-2.740849028653434	[30]	[13]	-9	hSpCas9	negative selection	12308312
38748743	38748766	20	-	28162770	OCIAML3	viability	GAGCGCAGCATCCAGCGCAGTGG	ACTR5	ENSG00000101442	-1.009045139603007	[7]	[11]	-6	hSpCas9	negative selection	12308313
38752188	38752211	20	-	28162770	OCIAML3	viability	TCAGCTGGAGGAGACGCTGGAGG	ACTR5	ENSG00000101442	-2.3782789492687257	[30]	[17]	-9	hSpCas9	negative selection	12308314
38752266	38752289	20	+	28162770	OCIAML3	viability	TGAGCACAGCTACATCGCTGAGG	ACTR5	ENSG00000101442	-1.4296208224232807	[57]	[64]	-7	hSpCas9	negative selection	12308315
38755071	38755094	20	+	28162770	OCIAML3	viability	GGCGGCAGCAGCAATTGCGGCGG	ACTR5	ENSG00000101442	-0.6311606387416292	[58]	[114]	-5	hSpCas9	negative selection	12308316
38755946	38755969	20	+	28162770	OCIAML3	viability	CCAGAAGCTCAGTATAGCAGTGG	ACTR5	ENSG00000101442	-0.1976547043102462	[67]	[178]	-1	hSpCas9	negative selection	12308317
38755994	38756017	20	+	28162770	OCIAML3	viability	AGCGGAAGTCAACCTCGAGGTGG	ACTR5	ENSG00000101442	-3.915935735211526	[4]	[0]	-9	hSpCas9	negative selection	12308318
38765465	38765488	20	-	28162770	OCIAML3	viability	GGTGTTTCCTCTGAAAACAAGGG	ACTR5	ENSG00000101442	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12308319