Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:93973
• Symbol:ACTR8
• Description:actin related protein 8

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTR8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
53870098	53870121	3	-	26472758	Jiyoye	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-1.1571768395399968	[416]	[140]	-7	hSpCas9	negative selection	2253
53871401	53871424	3	+	26472758	Jiyoye	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	1.0306120300416652	[73]	[113]	6	hSpCas9	negative selection	2254
53882052	53882075	3	-	26472758	Jiyoye	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-5.116386574551139	[45]	[0]	-9	hSpCas9	negative selection	2255
53882038	53882061	3	-	26472758	Jiyoye	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	0.9096757220350566	[35]	[50]	6	hSpCas9	negative selection	2256
53879947	53879970	3	-	26472758	Jiyoye	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-1.6401303332724833	[123]	[29]	-8	hSpCas9	negative selection	2257
53871331	53871354	3	-	26472758	Jiyoye	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.37285893455221886	[169]	[98]	-3	hSpCas9	negative selection	2258
53871271	53871294	3	-	26472758	Jiyoye	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-1.4889888075095867	[66]	[17]	-7	hSpCas9	negative selection	2259
53882062	53882085	3	-	26472758	Jiyoye	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-1.0333972098801083	[18]	[6]	-6	hSpCas9	negative selection	2260
53882028	53882051	3	-	26472758	Jiyoye	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-1.155419306186828	[191]	[64]	-7	hSpCas9	negative selection	2261
53875973	53875996	3	-	26472758	Jiyoye	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-3.052256237131424	[142]	[12]	-9	hSpCas9	negative selection	2262
53870098	53870121	3	-	26472758	KBM7	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-3.772925555389673	[2123,2240]	[72,77]	-9	hSpCas9	negative selection	193371
53871401	53871424	3	+	26472758	KBM7	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-1.495161502472871	[729,636]	[70,151]	-8	hSpCas9	negative selection	193372
53882052	53882075	3	-	26472758	KBM7	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-2.682667358564987	[395,369]	[16,37]	-9	hSpCas9	negative selection	193373
53882038	53882061	3	-	26472758	KBM7	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.299044165649876	[516,362]	[69,15]	-9	hSpCas9	negative selection	193374
53879947	53879970	3	-	26472758	KBM7	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.9774243510877322	[369,321]	[92,72]	-6	hSpCas9	negative selection	193375
53871331	53871354	3	-	26472758	KBM7	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.9921743936831567	[738,515]	[101,185]	-6	hSpCas9	negative selection	193376
53871271	53871294	3	-	26472758	KBM7	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-0.08562168914667301	[271,246]	[105,122]	-1	hSpCas9	negative selection	193377
53882062	53882085	3	-	26472758	KBM7	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-0.6005790507674695	[25,122]	[19,28]	-5	hSpCas9	negative selection	193378
53882028	53882051	3	-	26472758	KBM7	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-1.8095862960836566	[566,583]	[26,122]	-8	hSpCas9	negative selection	193379
53875973	53875996	3	-	26472758	KBM7	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-1.1523273095385727	[349,274]	[53,75]	-7	hSpCas9	negative selection	193380
53870098	53870121	3	-	26472758	Raji	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-1.5394289977325375	[976]	[77]	-8	hSpCas9	negative selection	384489
53871401	53871424	3	+	26472758	Raji	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-1.2693370323541424	[321]	[30]	-7	hSpCas9	negative selection	384490
53882052	53882075	3	-	26472758	Raji	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-5.159403005321302	[153]	[0]	-9	hSpCas9	negative selection	384491
53882038	53882061	3	-	26472758	Raji	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-3.699971386684005	[167]	[2]	-9	hSpCas9	negative selection	384492
53879947	53879970	3	-	26472758	Raji	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.668720452699565	[136]	[19]	-5	hSpCas9	negative selection	384493
53871331	53871354	3	-	26472758	Raji	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.27656964049200644	[216]	[60]	2	hSpCas9	negative selection	384494
53871271	53871294	3	-	26472758	Raji	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-0.47757896534755695	[179]	[29]	-4	hSpCas9	negative selection	384495
53882062	53882085	3	-	26472758	Raji	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	0.23291441745745844	[21]	[5]	2	hSpCas9	negative selection	384496
53882028	53882051	3	-	26472758	Raji	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-0.9096899779853419	[169]	[20]	-6	hSpCas9	negative selection	384497
53875973	53875996	3	-	26472758	Raji	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-1.433184845989103	[127]	[10]	-7	hSpCas9	negative selection	384498
53870098	53870121	3	-	26472758	K562	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-1.0105658439097076	[1536]	[643]	-5	hSpCas9	negative selection	575607
53871401	53871424	3	+	26472758	K562	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-0.2916341725737629	[521]	[359]	-2	hSpCas9	negative selection	575608
53882052	53882075	3	-	26472758	K562	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-6.558636056957532	[334]	[2]	-9	hSpCas9	negative selection	575609
53882038	53882061	3	-	26472758	K562	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.9164040666686133	[473]	[52]	-8	hSpCas9	negative selection	575610
53879947	53879970	3	-	26472758	K562	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.17218606675935727	[306]	[229]	-1	hSpCas9	negative selection	575611
53871331	53871354	3	-	26472758	K562	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.28446784864862057	[491]	[340]	-2	hSpCas9	negative selection	575612
53871271	53871294	3	-	26472758	K562	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-0.322949713039971	[162]	[109]	-2	hSpCas9	negative selection	575613
53882062	53882085	3	-	26472758	K562	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-0.5145731728297585	[43]	[25]	-3	hSpCas9	negative selection	575614
53882028	53882051	3	-	26472758	K562	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-2.5056030193252057	[443]	[65]	-8	hSpCas9	negative selection	575615
53875973	53875996	3	-	26472758	K562	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-1.839817809501585	[334]	[78]	-7	hSpCas9	negative selection	575616
53871331	53871354	3	-	26627737	DLD1	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-2.357893888354469	[303]	[23,33,0]	-9	hSpCas9	negative selection	822742
53873054	53873077	3	+	26627737	DLD1	viability	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	0.8600406785402418	[438]	[269,277,206]	8	hSpCas9	negative selection	822743
53874299	53874322	3	-	26627737	DLD1	viability	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	-0.9018857735663915	[474]	[26,175,44]	-7	hSpCas9	negative selection	822744
53877366	53877389	3	-	26627737	DLD1	viability	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-0.8195763490339916	[130]	[30,1,33]	-7	hSpCas9	negative selection	822745
53879984	53880007	3	-	26627737	DLD1	viability	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.4632967684009242	[712]	[122,278,97]	-5	hSpCas9	negative selection	822746
53882074	53882097	3	+	26627737	DLD1	viability	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-1.3637446834937028	[1205]	[74,175,183]	-8	hSpCas9	negative selection	822747
53871331	53871354	3	-	26627737	GBM cells	viability after 5 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.8338940938068646	[230]	[63,74]	-8	hSpCas9	negative selection	905057
53873054	53873077	3	+	26627737	GBM cells	viability after 5 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	0.39119437309698973	[299]	[229,191]	6	hSpCas9	negative selection	905058
53874299	53874322	3	-	26627737	GBM cells	viability after 5 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	1.8010665514875412	[60]	[116,110]	9	hSpCas9	negative selection	905059
53877366	53877389	3	-	26627737	GBM cells	viability after 5 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-0.4694735310943371	[141]	[35,73]	-6	hSpCas9	negative selection	905060
53879984	53880007	3	-	26627737	GBM cells	viability after 5 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.3986412710828453	[718]	[271,312]	-6	hSpCas9	negative selection	905061
53882074	53882097	3	+	26627737	GBM cells	viability after 5 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	0.07815355260453805	[445]	[281,222]	1	hSpCas9	negative selection	905062
53871331	53871354	3	-	26627737	GBM cells	viability after 13 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.8922018324122616	[230]	[46,22]	-9	hSpCas9	negative selection	987372
53873054	53873077	3	+	26627737	GBM cells	viability after 13 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	0.6409664358985445	[299]	[319,199]	7	hSpCas9	negative selection	987373
53874299	53874322	3	-	26627737	GBM cells	viability after 13 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	1.3349430303594723	[60]	[104,65]	9	hSpCas9	negative selection	987374
53877366	53877389	3	-	26627737	GBM cells	viability after 13 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.5844429442598145	[141]	[28,22]	-9	hSpCas9	negative selection	987375
53879984	53880007	3	-	26627737	GBM cells	viability after 13 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.7486668742180864	[718]	[240,224]	-7	hSpCas9	negative selection	987376
53882074	53882097	3	+	26627737	GBM cells	viability after 13 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.06962167858962598	[445]	[309,165]	-1	hSpCas9	negative selection	987377
53871331	53871354	3	-	26627737	GBM cells	viability after 21 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-2.3398940398859334	[230]	[17,30]	-9	hSpCas9	negative selection	1069687
53873054	53873077	3	+	26627737	GBM cells	viability after 21 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	0.5665636607143036	[299]	[255,227]	6	hSpCas9	negative selection	1069688
53874299	53874322	3	-	26627737	GBM cells	viability after 21 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	1.6831515859590986	[60]	[119,93]	9	hSpCas9	negative selection	1069689
53877366	53877389	3	-	26627737	GBM cells	viability after 21 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-2.3009110199090617	[141]	[11,18]	-9	hSpCas9	negative selection	1069690
53879984	53880007	3	-	26627737	GBM cells	viability after 21 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.5921257252528824	[718]	[314,207]	-5	hSpCas9	negative selection	1069691
53882074	53882097	3	+	26627737	GBM cells	viability after 21 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.0064475911318142565	[445]	[235,245]	0	hSpCas9	negative selection	1069692
53871331	53871354	3	-	26627737	RPE1	viability after 9 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.6137155528655658	[877]	[122,46]	-8	hSpCas9	negative selection	1152002
53873054	53873077	3	+	26627737	RPE1	viability after 9 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	2.0268875614175164	[367]	[534,384]	8	hSpCas9	negative selection	1152003
53874299	53874322	3	-	26627737	RPE1	viability after 9 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.9607246922654932	[377]	[297,142]	6	hSpCas9	negative selection	1152004
53877366	53877389	3	-	26627737	RPE1	viability after 9 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.6658726324670317	[383]	[43,29]	-8	hSpCas9	negative selection	1152005
53879984	53880007	3	-	26627737	RPE1	viability after 9 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	0.4109775203399491	[1093]	[581,291]	3	hSpCas9	negative selection	1152006
53882074	53882097	3	+	26627737	RPE1	viability after 9 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.8952557216958991	[1648]	[246,316]	-6	hSpCas9	negative selection	1152007
53871331	53871354	3	-	26627737	RPE1	viability after 12 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.2854564633130297	[877]	[139,50]	-7	hSpCas9	negative selection	1234317
53873054	53873077	3	+	26627737	RPE1	viability after 12 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	2.146112575735036	[367]	[492,378]	9	hSpCas9	negative selection	1234318
53874299	53874322	3	-	26627737	RPE1	viability after 12 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	1.5409530518968944	[377]	[329,258]	8	hSpCas9	negative selection	1234319
53877366	53877389	3	-	26627737	RPE1	viability after 12 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-2.0188524844710622	[383]	[6,44]	-8	hSpCas9	negative selection	1234320
53879984	53880007	3	-	26627737	RPE1	viability after 12 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	0.43111153914658	[1093]	[558,223]	3	hSpCas9	negative selection	1234321
53882074	53882097	3	+	26627737	RPE1	viability after 12 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-1.3614092330669119	[1648]	[237,102]	-7	hSpCas9	negative selection	1234322
53871331	53871354	3	-	26627737	RPE1	viability after 15 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.894825714107137	[877]	[134,0]	-8	hSpCas9	negative selection	1316632
53873054	53873077	3	+	26627737	RPE1	viability after 15 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	1.8247702444027978	[367]	[465,274]	8	hSpCas9	negative selection	1316633
53874299	53874322	3	-	26627737	RPE1	viability after 15 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.7812401083635984	[377]	[224,143]	5	hSpCas9	negative selection	1316634
53877366	53877389	3	-	26627737	RPE1	viability after 15 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-3.417973973840092	[383]	[0,18]	-9	hSpCas9	negative selection	1316635
53879984	53880007	3	-	26627737	RPE1	viability after 15 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	0.7470176060226033	[1093]	[806,241]	4	hSpCas9	negative selection	1316636
53882074	53882097	3	+	26627737	RPE1	viability after 15 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.8107739137825913	[1648]	[410,125]	-5	hSpCas9	negative selection	1316637
53871331	53871354	3	-	26627737	RPE1	viability after 18 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-4.201178317374409	[877]	[23,0]	-9	hSpCas9	negative selection	1398947
53873054	53873077	3	+	26627737	RPE1	viability after 18 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	1.7438411125123445	[367]	[408,250]	8	hSpCas9	negative selection	1398948
53874299	53874322	3	-	26627737	RPE1	viability after 18 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	1.0438511676364384	[377]	[204,215]	6	hSpCas9	negative selection	1398949
53877366	53877389	3	-	26627737	RPE1	viability after 18 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-3.008063688560207	[383]	[23,0]	-9	hSpCas9	negative selection	1398950
53879984	53880007	3	-	26627737	RPE1	viability after 18 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	0.8336061311934524	[1093]	[617,427]	5	hSpCas9	negative selection	1398951
53882074	53882097	3	+	26627737	RPE1	viability after 18 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-1.6512865423056011	[1648]	[204,73]	-7	hSpCas9	negative selection	1398952
53871331	53871354	3	-	26627737	HeLa	viability after 8 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.047100612136149245	[214]	[202,96,18]	0	hSpCas9	negative selection	1481262
53873054	53873077	3	+	26627737	HeLa	viability after 8 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.18937828581697913	[599]	[310,150,241]	-2	hSpCas9	negative selection	1481263
53874299	53874322	3	-	26627737	HeLa	viability after 8 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	-0.2503291237489255	[605]	[490,65,170]	-2	hSpCas9	negative selection	1481264
53877366	53877389	3	-	26627737	HeLa	viability after 8 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.0876823311365857	[137]	[49,17,21]	-8	hSpCas9	negative selection	1481265
53879984	53880007	3	-	26627737	HeLa	viability after 8 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.1170778250914506	[854]	[364,296,369]	-1	hSpCas9	negative selection	1481266
53882074	53882097	3	+	26627737	HeLa	viability after 8 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.5617531570202692	[1183]	[460,383,234]	-5	hSpCas9	negative selection	1481267
53871331	53871354	3	-	26627737	HeLa	viability after 12 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.9129428514372329	[214]	[28,56,53]	-7	hSpCas9	negative selection	1563577
53873054	53873077	3	+	26627737	HeLa	viability after 12 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.8502927661100971	[599]	[15,175,212]	-7	hSpCas9	negative selection	1563578
53874299	53874322	3	-	26627737	HeLa	viability after 12 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	-0.22969101629798028	[605]	[320,249,68]	-2	hSpCas9	negative selection	1563579
53877366	53877389	3	-	26627737	HeLa	viability after 12 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-0.07526438553564097	[137]	[14,65,78]	0	hSpCas9	negative selection	1563580
53879984	53880007	3	-	26627737	HeLa	viability after 12 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.9308051729230368	[854]	[294,130,138]	-7	hSpCas9	negative selection	1563581
53882074	53882097	3	+	26627737	HeLa	viability after 12 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.23262670223598048	[1183]	[274,559,394]	-2	hSpCas9	negative selection	1563582
53871331	53871354	3	-	26627737	HeLa	viability after 15 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.041627313299027136	[214]	[108,34,128]	0	hSpCas9	negative selection	1645892
53873054	53873077	3	+	26627737	HeLa	viability after 15 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.40753546133693913	[599]	[109,227,217]	-4	hSpCas9	negative selection	1645893
53874299	53874322	3	-	26627737	HeLa	viability after 15 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.0966931026114407	[605]	[326,351,98]	0	hSpCas9	negative selection	1645894
53877366	53877389	3	-	26627737	HeLa	viability after 15 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-3.0096661448588753	[137]	[0,0,19]	-9	hSpCas9	negative selection	1645895
53879984	53880007	3	-	26627737	HeLa	viability after 15 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.5998862238925531	[854]	[274,260,145]	-5	hSpCas9	negative selection	1645896
53882074	53882097	3	+	26627737	HeLa	viability after 15 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.2602261893152187	[1183]	[559,246,397]	-2	hSpCas9	negative selection	1645897
53871331	53871354	3	-	26627737	HeLa	viability after 18 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.04228416244940669	[214]	[73,27,128]	0	hSpCas9	negative selection	1728207
53873054	53873077	3	+	26627737	HeLa	viability after 18 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.4263386332875591	[599]	[68,188,217]	-4	hSpCas9	negative selection	1728208
53874299	53874322	3	-	26627737	HeLa	viability after 18 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.13065109004954256	[605]	[231,290,98]	1	hSpCas9	negative selection	1728209
53877366	53877389	3	-	26627737	HeLa	viability after 18 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-2.9608874646265146	[137]	[0,0,19]	-9	hSpCas9	negative selection	1728210
53879984	53880007	3	-	26627737	HeLa	viability after 18 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.5908970655678965	[854]	[180,223,145]	-5	hSpCas9	negative selection	1728211
53882074	53882097	3	+	26627737	HeLa	viability after 18 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.25133362099274525	[1183]	[376,208,397]	-2	hSpCas9	negative selection	1728212
53871331	53871354	3	-	26627737	HCT116	viability after 6 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.8771531088289001	[799]	[366,155]	5	hSpCas9	negative selection	1810522
53873054	53873077	3	+	26627737	HCT116	viability after 6 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.6820072036625029	[855]	[157,42]	-4	hSpCas9	negative selection	1810523
53874299	53874322	3	-	26627737	HCT116	viability after 6 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	2.519080405168401	[420]	[1050,8]	9	hSpCas9	negative selection	1810524
53877366	53877389	3	-	26627737	HCT116	viability after 6 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-3.316222280921431	[320]	[6,3]	-9	hSpCas9	negative selection	1810525
53879984	53880007	3	-	26627737	HCT116	viability after 6 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	2.5048804875833297	[852]	[298,1015]	9	hSpCas9	negative selection	1810526
53882074	53882097	3	+	26627737	HCT116	viability after 6 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	1.6102479217436232	[1118]	[616,492]	8	hSpCas9	negative selection	1810527
53871331	53871354	3	-	26627737	HCT116	viability after 8 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.2742711556139135	[202]	[139,136,128]	3	hSpCas9	negative selection	1892837
53873054	53873077	3	+	26627737	HCT116	viability after 8 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-1.2255454407149189	[654]	[103,192,164]	-9	hSpCas9	negative selection	1892838
53874299	53874322	3	-	26627737	HCT116	viability after 8 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.5282021954899415	[138]	[130,111,88]	5	hSpCas9	negative selection	1892839
53877366	53877389	3	-	26627737	HCT116	viability after 8 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.9035815921449624	[246]	[16,72,18]	-9	hSpCas9	negative selection	1892840
53879984	53880007	3	-	26627737	HCT116	viability after 8 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	0.012468562630731372	[581]	[263,267,435]	0	hSpCas9	negative selection	1892841
53882074	53882097	3	+	26627737	HCT116	viability after 8 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	0.2332740079841631	[621]	[365,355,484]	2	hSpCas9	negative selection	1892842
53871331	53871354	3	-	26627737	HCT116	viability after 9 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.5893023304276235	[799]	[51,85]	-8	hSpCas9	negative selection	1975152
53873054	53873077	3	+	26627737	HCT116	viability after 9 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	0.21601744308189208	[855]	[422,140]	1	hSpCas9	negative selection	1975153
53874299	53874322	3	-	26627737	HCT116	viability after 9 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.6541844433736079	[420]	[358,32]	5	hSpCas9	negative selection	1975154
53877366	53877389	3	-	26627737	HCT116	viability after 9 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-0.2253969770452302	[320]	[117,37]	-1	hSpCas9	negative selection	1975155
53879984	53880007	3	-	26627737	HCT116	viability after 9 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	0.7818049205395736	[852]	[838,37]	5	hSpCas9	negative selection	1975156
53882074	53882097	3	+	26627737	HCT116	viability after 9 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	1.526034424548947	[1118]	[621,1048]	8	hSpCas9	negative selection	1975157
53871331	53871354	3	-	26627737	HCT116	viability after 12 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.5212662835834124	[202]	[52,120,51]	-5	hSpCas9	negative selection	2057467
53873054	53873077	3	+	26627737	HCT116	viability after 12 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-1.1489769453509708	[654]	[110,255,104]	-8	hSpCas9	negative selection	2057468
53874299	53874322	3	-	26627737	HCT116	viability after 12 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	1.199122948683998	[138]	[203,168,126]	8	hSpCas9	negative selection	2057469
53877366	53877389	3	-	26627737	HCT116	viability after 12 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-2.6909464360144195	[246]	[22,17,18]	-9	hSpCas9	negative selection	2057470
53879984	53880007	3	-	26627737	HCT116	viability after 12 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.14575428198081153	[581]	[373,200,243]	-1	hSpCas9	negative selection	2057471
53882074	53882097	3	+	26627737	HCT116	viability after 12 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	0.481178443140573	[621]	[396,453,522]	4	hSpCas9	negative selection	2057472
53871331	53871354	3	-	26627737	HCT116	viability after 15 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.1380876354042102	[202]	[50,81,25]	-8	hSpCas9	negative selection	2139782
53873054	53873077	3	+	26627737	HCT116	viability after 15 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-1.1873409882503154	[654]	[120,273,95]	-8	hSpCas9	negative selection	2139783
53874299	53874322	3	-	26627737	HCT116	viability after 15 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	1.3087436873272493	[138]	[301,193,110]	8	hSpCas9	negative selection	2139784
53877366	53877389	3	-	26627737	HCT116	viability after 15 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.6312005582949438	[246]	[33,60,40]	-9	hSpCas9	negative selection	2139785
53879984	53880007	3	-	26627737	HCT116	viability after 15 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.15079371910870654	[581]	[540,139,251]	-1	hSpCas9	negative selection	2139786
53882074	53882097	3	+	26627737	HCT116	viability after 15 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	0.015980517645743264	[621]	[268,495,307]	0	hSpCas9	negative selection	2139787
53871331	53871354	3	-	26627737	HCT116	viability after 18 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.9162443352038537	[202]	[8,103,38]	-7	hSpCas9	negative selection	2222097
53873054	53873077	3	+	26627737	HCT116	viability after 18 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.6566325230612906	[654]	[69,259,271]	-6	hSpCas9	negative selection	2222098
53874299	53874322	3	-	26627737	HCT116	viability after 18 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	1.6474109871865696	[138]	[254,196,178]	9	hSpCas9	negative selection	2222099
53877366	53877389	3	-	26627737	HCT116	viability after 18 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-3.6770423628261506	[246]	[2,11,12]	-9	hSpCas9	negative selection	2222100
53879984	53880007	3	-	26627737	HCT116	viability after 18 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.01680264315277047	[581]	[188,308,336]	0	hSpCas9	negative selection	2222101
53882074	53882097	3	+	26627737	HCT116	viability after 18 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.08592431294724001	[621]	[212,328,305]	0	hSpCas9	negative selection	2222102
53882018	53882041	3	-	24336569	HL60	viability	AGGAGCAGCGCGGCGTGAAGCGG	ACTR8	ENSG00000113812	-0.054836777447225815	[1690]	[3444]	0	hSpCas9	negative selection	2246503
53882028	53882051	3	-	24336569	HL60	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-0.2777723926618768	[675]	[1179]	-2	hSpCas9	negative selection	2246504
53882038	53882061	3	-	24336569	HL60	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.1944359135855054	[862]	[398]	-9	hSpCas9	negative selection	2246505
53882044	53882067	3	-	24336569	HL60	viability	AAAGGAGAAGGGCGGCGAGAAGG	ACTR8	ENSG00000113812	-0.7680307999069895	[1021]	[1269]	-6	hSpCas9	negative selection	2246506
53882052	53882075	3	-	24336569	HL60	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-3.1617916655764136	[1310]	[309]	-9	hSpCas9	negative selection	2246507
53882062	53882085	3	-	24336569	HL60	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-0.4885088091542096	[239]	[361]	-4	hSpCas9	negative selection	2246508
53882067	53882090	3	-	24336569	HL60	viability	GAGAAGGGTGATACGGAGAACGG	ACTR8	ENSG00000113812	-2.130331218298229	[1170]	[565]	-9	hSpCas9	negative selection	2246509
53882074	53882097	3	-	24336569	HL60	viability	CCAGGCTGAGAAGGGTGATACGG	ACTR8	ENSG00000113812	0.8508081823292237	[615]	[2350]	7	hSpCas9	negative selection	2246510
53882082	53882105	3	-	24336569	HL60	viability	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	-0.03982961192093243	[443]	[913]	0	hSpCas9	negative selection	2246511
53882092	53882115	3	-	24336569	HL60	viability	GTCTCCGGCCATAATGACCCAGG	ACTR8	ENSG00000113812	-1.3850136662014043	[194]	[157]	-8	hSpCas9	negative selection	2246512
53882018	53882041	3	-	24336569	KBM7	viability	AGGAGCAGCGCGGCGTGAAGCGG	ACTR8	ENSG00000113812	-1.1807360518307903	[1323]	[1592]	-7	hSpCas9	negative selection	2313680
53882028	53882051	3	-	24336569	KBM7	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-2.1394569011865503	[566]	[350]	-8	hSpCas9	negative selection	2313681
53882038	53882061	3	-	24336569	KBM7	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-4.567488660284079	[651]	[74]	-9	hSpCas9	negative selection	2313682
53882044	53882067	3	-	24336569	KBM7	viability	AAAGGAGAAGGGCGGCGAGAAGG	ACTR8	ENSG00000113812	0.3508598529242841	[741]	[2580]	3	hSpCas9	negative selection	2313683
53882052	53882075	3	-	24336569	KBM7	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-2.938498207354901	[1157]	[411]	-9	hSpCas9	negative selection	2313684
53882062	53882085	3	-	24336569	KBM7	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-0.13945690118655063	[440]	[1091]	-1	hSpCas9	negative selection	2313685
53882067	53882090	3	-	24336569	KBM7	viability	GAGAAGGGTGATACGGAGAACGG	ACTR8	ENSG00000113812	-1.9936999710673726	[567]	[388]	-8	hSpCas9	negative selection	2313686
53882074	53882097	3	-	24336569	KBM7	viability	CCAGGCTGAGAAGGGTGATACGG	ACTR8	ENSG00000113812	-0.268830344719564	[814]	[1844]	-2	hSpCas9	negative selection	2313687
53882082	53882105	3	-	24336569	KBM7	viability	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	0.1724302512714745	[609]	[1874]	1	hSpCas9	negative selection	2313688
53882092	53882115	3	-	24336569	KBM7	viability	GTCTCCGGCCATAATGACCCAGG	ACTR8	ENSG00000113812	-2.995547489787837	[230]	[78]	-9	hSpCas9	negative selection	2313689
53873897	53873920	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCCACCTTCCAG	ACTR8	ENSG00000113812	-0.9430062856730932	[147,123]	[18,10]	-5	dCas9-VP64	positive selection	2422288
53873897	53873920	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCCACCTTCCAG	ACTR8	ENSG00000113812	1.0287528959230179	[63,82]	[22,72]	6	dCas9-VP64	positive selection	2517543
53881974	53881997	3	+	27260157	DLD1	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.356571502486441	[]	[]	-3	hSpCas9	negative selection	2578875
53882062	53882085	3	-	27260157	DLD1	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-1.85152550268747	[]	[]	-8	hSpCas9	negative selection	2580793
53882092	53882115	3	-	27260157	DLD1	viability	GTCTCCGGCCATAATGACCCAGG	ACTR8	ENSG00000113812	-2.03495531380647	[]	[]	-8	hSpCas9	negative selection	2580872
53878372	53878395	3	+	27260157	DLD1	viability	AGGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-1.59764326545613	[]	[]	-8	hSpCas9	negative selection	2585184
53880009	53880032	3	+	27260157	DLD1	viability	ATGACGTGAGGAATGCTGGCAGG	ACTR8	ENSG00000113812	0.0877140424857473	[]	[]	3	hSpCas9	negative selection	2604192
53877722	53877745	3	+	27260157	DLD1	viability	AGGTCGCATCTGCTTATTGTAGG	ACTR8	ENSG00000113812	-1.6180441507832	[]	[]	-8	hSpCas9	negative selection	2604194
53882038	53882061	3	-	27260157	DLD1	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-1.81770664600254	[]	[]	-8	hSpCas9	negative selection	2606871
53877366	53877389	3	-	27260157	DLD1	viability	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.0700741055481	[]	[]	-7	hSpCas9	negative selection	2607805
53882044	53882067	3	-	27260157	DLD1	viability	AAAGGAGAAGGGCGGCGAGAAGG	ACTR8	ENSG00000113812	0.515596376004722	[]	[]	8	hSpCas9	negative selection	2609247
53882074	53882097	3	-	27260157	DLD1	viability	CCAGGCTGAGAAGGGTGATACGG	ACTR8	ENSG00000113812	-0.898241890638554	[]	[]	-6	hSpCas9	negative selection	2609366
53882018	53882041	3	-	27260157	DLD1	viability	AGGAGCAGCGCGGCGTGAAGCGG	ACTR8	ENSG00000113812	0.26531763149512	[]	[]	4	hSpCas9	negative selection	2611957
53881993	53882016	3	-	27260157	DLD1	viability	CATCGTGCCCGCGCTGGTGCCGG	ACTR8	ENSG00000113812	0.267761331283836	[]	[]	4	hSpCas9	negative selection	2612234
53881985	53882008	3	+	27260157	DLD1	viability	CAGCGACTCCGGCACCAGCGCGG	ACTR8	ENSG00000113812	-0.0731759904291626	[]	[]	0	hSpCas9	negative selection	2612274
53882067	53882090	3	-	27260157	DLD1	viability	GAGAAGGGTGATACGGAGAACGG	ACTR8	ENSG00000113812	-1.50661888248996	[]	[]	-8	hSpCas9	negative selection	2612931
53882028	53882051	3	-	27260157	DLD1	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-1.35767699684505	[]	[]	-8	hSpCas9	negative selection	2620957
53882074	53882097	3	+	27260157	DLD1	viability	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.791630836261339	[]	[]	-6	hSpCas9	negative selection	2641153
53882082	53882105	3	-	27260157	DLD1	viability	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	-0.404812454410915	[]	[]	-3	hSpCas9	negative selection	2641679
53882052	53882075	3	-	27260157	DLD1	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-4.34197827342197	[]	[]	-9	hSpCas9	negative selection	2641754
53881995	53882018	3	+	27260157	DLD1	viability	GGCACCAGCGCGGGCACGATGGG	ACTR8	ENSG00000113812	-0.851270943563692	[]	[]	-6	hSpCas9	negative selection	2645793
53881974	53881997	3	+	27260157	HT1080	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.656141848830975	[]	[]	-8	hSpCas9	negative selection	2655005
53882062	53882085	3	-	27260157	HT1080	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-1.87889459089112	[]	[]	-9	hSpCas9	negative selection	2656923
53882092	53882115	3	-	27260157	HT1080	viability	GTCTCCGGCCATAATGACCCAGG	ACTR8	ENSG00000113812	-3.0110696711466	[]	[]	-9	hSpCas9	negative selection	2657002
53878372	53878395	3	+	27260157	HT1080	viability	AGGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-1.45477173930858	[]	[]	-9	hSpCas9	negative selection	2661314
53880009	53880032	3	+	27260157	HT1080	viability	ATGACGTGAGGAATGCTGGCAGG	ACTR8	ENSG00000113812	0.189100097070725	[]	[]	1	hSpCas9	negative selection	2680322
53877722	53877745	3	+	27260157	HT1080	viability	AGGTCGCATCTGCTTATTGTAGG	ACTR8	ENSG00000113812	-2.26220849061387	[]	[]	-9	hSpCas9	negative selection	2680324
53882038	53882061	3	-	27260157	HT1080	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-0.161446149921572	[]	[]	0	hSpCas9	negative selection	2683001
53877366	53877389	3	-	27260157	HT1080	viability	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-3.03125281523056	[]	[]	-9	hSpCas9	negative selection	2683935
53882044	53882067	3	-	27260157	HT1080	viability	AAAGGAGAAGGGCGGCGAGAAGG	ACTR8	ENSG00000113812	0.755432316995579	[]	[]	6	hSpCas9	negative selection	2685377
53882074	53882097	3	-	27260157	HT1080	viability	CCAGGCTGAGAAGGGTGATACGG	ACTR8	ENSG00000113812	-1.5521857125652	[]	[]	-9	hSpCas9	negative selection	2685496
53882018	53882041	3	-	27260157	HT1080	viability	AGGAGCAGCGCGGCGTGAAGCGG	ACTR8	ENSG00000113812	-0.457848438389773	[]	[]	-7	hSpCas9	negative selection	2688087
53881993	53882016	3	-	27260157	HT1080	viability	CATCGTGCCCGCGCTGGTGCCGG	ACTR8	ENSG00000113812	-0.0145400583314145	[]	[]	0	hSpCas9	negative selection	2688364
53881985	53882008	3	+	27260157	HT1080	viability	CAGCGACTCCGGCACCAGCGCGG	ACTR8	ENSG00000113812	-0.657238017982953	[]	[]	-8	hSpCas9	negative selection	2688404
53882067	53882090	3	-	27260157	HT1080	viability	GAGAAGGGTGATACGGAGAACGG	ACTR8	ENSG00000113812	-2.99860872898891	[]	[]	-9	hSpCas9	negative selection	2689061
53882028	53882051	3	-	27260157	HT1080	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-1.75316682122783	[]	[]	-9	hSpCas9	negative selection	2697087
53882074	53882097	3	+	27260157	HT1080	viability	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.516662975176355	[]	[]	-7	hSpCas9	negative selection	2717283
53882082	53882105	3	-	27260157	HT1080	viability	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	-1.00434812435693	[]	[]	-8	hSpCas9	negative selection	2717809
53882052	53882075	3	-	27260157	HT1080	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-3.34437948708982	[]	[]	-9	hSpCas9	negative selection	2717884
53881995	53882018	3	+	27260157	HT1080	viability	GGCACCAGCGCGGGCACGATGGG	ACTR8	ENSG00000113812	-1.69407813238497	[]	[]	-9	hSpCas9	negative selection	2721923
53881974	53881997	3	+	27260157	MKN45	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-1.28374104417913	[]	[]	-8	hSpCas9	negative selection	2731135
53882062	53882085	3	-	27260157	MKN45	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-1.64746614901694	[]	[]	-9	hSpCas9	negative selection	2733053
53882092	53882115	3	-	27260157	MKN45	viability	GTCTCCGGCCATAATGACCCAGG	ACTR8	ENSG00000113812	-1.59798554945643	[]	[]	-9	hSpCas9	negative selection	2733132
53878372	53878395	3	+	27260157	MKN45	viability	AGGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.503226422173503	[]	[]	-6	hSpCas9	negative selection	2737444
53880009	53880032	3	+	27260157	MKN45	viability	ATGACGTGAGGAATGCTGGCAGG	ACTR8	ENSG00000113812	0.0707590442156619	[]	[]	0	hSpCas9	negative selection	2756452
53877722	53877745	3	+	27260157	MKN45	viability	AGGTCGCATCTGCTTATTGTAGG	ACTR8	ENSG00000113812	-1.10210962411119	[]	[]	-8	hSpCas9	negative selection	2756454
53882038	53882061	3	-	27260157	MKN45	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-1.10242671475592	[]	[]	-8	hSpCas9	negative selection	2759131
53877366	53877389	3	-	27260157	MKN45	viability	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.41575245563621	[]	[]	-8	hSpCas9	negative selection	2760065
53882044	53882067	3	-	27260157	MKN45	viability	AAAGGAGAAGGGCGGCGAGAAGG	ACTR8	ENSG00000113812	-0.398665347367376	[]	[]	-1	hSpCas9	negative selection	2761507
53882074	53882097	3	-	27260157	MKN45	viability	CCAGGCTGAGAAGGGTGATACGG	ACTR8	ENSG00000113812	-1.26512965977004	[]	[]	-8	hSpCas9	negative selection	2761626
53882018	53882041	3	-	27260157	MKN45	viability	AGGAGCAGCGCGGCGTGAAGCGG	ACTR8	ENSG00000113812	0.118353039798056	[]	[]	4	hSpCas9	negative selection	2764217
53881993	53882016	3	-	27260157	MKN45	viability	CATCGTGCCCGCGCTGGTGCCGG	ACTR8	ENSG00000113812	-0.367500862757362	[]	[]	-1	hSpCas9	negative selection	2764494
53881985	53882008	3	+	27260157	MKN45	viability	CAGCGACTCCGGCACCAGCGCGG	ACTR8	ENSG00000113812	0.448761845952229	[]	[]	6	hSpCas9	negative selection	2764534
53882067	53882090	3	-	27260157	MKN45	viability	GAGAAGGGTGATACGGAGAACGG	ACTR8	ENSG00000113812	-0.968369826567574	[]	[]	-7	hSpCas9	negative selection	2765191
53882028	53882051	3	-	27260157	MKN45	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-0.958420892853423	[]	[]	-7	hSpCas9	negative selection	2773217
53882074	53882097	3	+	27260157	MKN45	viability	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.376661276163394	[]	[]	-1	hSpCas9	negative selection	2793413
53882082	53882105	3	-	27260157	MKN45	viability	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	0.439207022516393	[]	[]	6	hSpCas9	negative selection	2793939
53882052	53882075	3	-	27260157	MKN45	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-2.48500210559778	[]	[]	-9	hSpCas9	negative selection	2794014
53881995	53882018	3	+	27260157	MKN45	viability	GGCACCAGCGCGGGCACGATGGG	ACTR8	ENSG00000113812	-1.7290798646972	[]	[]	-9	hSpCas9	negative selection	2798053
53881974	53881997	3	+	27260157	RKO	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-1.83773528724246	[]	[]	-9	hSpCas9	negative selection	2807265
53882062	53882085	3	-	27260157	RKO	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-2.01165771896609	[]	[]	-9	hSpCas9	negative selection	2809183
53882092	53882115	3	-	27260157	RKO	viability	GTCTCCGGCCATAATGACCCAGG	ACTR8	ENSG00000113812	-3.30782016647545	[]	[]	-9	hSpCas9	negative selection	2809262
53878372	53878395	3	+	27260157	RKO	viability	AGGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-1.26605238448388	[]	[]	-8	hSpCas9	negative selection	2813574
53880009	53880032	3	+	27260157	RKO	viability	ATGACGTGAGGAATGCTGGCAGG	ACTR8	ENSG00000113812	-0.320065001684104	[]	[]	-6	hSpCas9	negative selection	2832582
53877722	53877745	3	+	27260157	RKO	viability	AGGTCGCATCTGCTTATTGTAGG	ACTR8	ENSG00000113812	-1.77637721436538	[]	[]	-9	hSpCas9	negative selection	2832584
53882038	53882061	3	-	27260157	RKO	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.23286426352647	[]	[]	-9	hSpCas9	negative selection	2835261
53877366	53877389	3	-	27260157	RKO	viability	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-3.74461450785281	[]	[]	-9	hSpCas9	negative selection	2836195
53882044	53882067	3	-	27260157	RKO	viability	AAAGGAGAAGGGCGGCGAGAAGG	ACTR8	ENSG00000113812	0.0583596021218096	[]	[]	0	hSpCas9	negative selection	2837637
53882074	53882097	3	-	27260157	RKO	viability	CCAGGCTGAGAAGGGTGATACGG	ACTR8	ENSG00000113812	-2.52517403670882	[]	[]	-9	hSpCas9	negative selection	2837756
53882018	53882041	3	-	27260157	RKO	viability	AGGAGCAGCGCGGCGTGAAGCGG	ACTR8	ENSG00000113812	-0.410162416347792	[]	[]	-6	hSpCas9	negative selection	2840347
53881993	53882016	3	-	27260157	RKO	viability	CATCGTGCCCGCGCTGGTGCCGG	ACTR8	ENSG00000113812	-0.972344528703864	[]	[]	-8	hSpCas9	negative selection	2840624
53881985	53882008	3	+	27260157	RKO	viability	CAGCGACTCCGGCACCAGCGCGG	ACTR8	ENSG00000113812	-1.18872612274745	[]	[]	-8	hSpCas9	negative selection	2840664
53882067	53882090	3	-	27260157	RKO	viability	GAGAAGGGTGATACGGAGAACGG	ACTR8	ENSG00000113812	-3.09517004189863	[]	[]	-9	hSpCas9	negative selection	2841321
53882028	53882051	3	-	27260157	RKO	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-2.4240376201762	[]	[]	-9	hSpCas9	negative selection	2849347
53882074	53882097	3	+	27260157	RKO	viability	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-2.00407312598273	[]	[]	-9	hSpCas9	negative selection	2869543
53882082	53882105	3	-	27260157	RKO	viability	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	-2.36273115614646	[]	[]	-9	hSpCas9	negative selection	2870069
53882052	53882075	3	-	27260157	RKO	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-4.19414752441844	[]	[]	-9	hSpCas9	negative selection	2870144
53881995	53882018	3	+	27260157	RKO	viability	GGCACCAGCGCGGGCACGATGGG	ACTR8	ENSG00000113812	-3.63672351290514	[]	[]	-9	hSpCas9	negative selection	2874183
53881974	53881997	3	+	27260157	SF268	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.47309453817785	[]	[]	-4	hSpCas9	negative selection	2883395
53882062	53882085	3	-	27260157	SF268	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-1.66980913055315	[]	[]	-8	hSpCas9	negative selection	2885313
53882092	53882115	3	-	27260157	SF268	viability	GTCTCCGGCCATAATGACCCAGG	ACTR8	ENSG00000113812	-1.59675672831759	[]	[]	-8	hSpCas9	negative selection	2885392
53878372	53878395	3	+	27260157	SF268	viability	AGGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.562919011052709	[]	[]	-4	hSpCas9	negative selection	2889704
53880009	53880032	3	+	27260157	SF268	viability	ATGACGTGAGGAATGCTGGCAGG	ACTR8	ENSG00000113812	1.13863727692269	[]	[]	9	hSpCas9	negative selection	2908712
53877722	53877745	3	+	27260157	SF268	viability	AGGTCGCATCTGCTTATTGTAGG	ACTR8	ENSG00000113812	-1.42786340614304	[]	[]	-8	hSpCas9	negative selection	2908714
53882038	53882061	3	-	27260157	SF268	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.4116974498981	[]	[]	-9	hSpCas9	negative selection	2911391
53877366	53877389	3	-	27260157	SF268	viability	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.26617171993918	[]	[]	-7	hSpCas9	negative selection	2912325
53882044	53882067	3	-	27260157	SF268	viability	AAAGGAGAAGGGCGGCGAGAAGG	ACTR8	ENSG00000113812	-0.248542842845294	[]	[]	-2	hSpCas9	negative selection	2913767
53882074	53882097	3	-	27260157	SF268	viability	CCAGGCTGAGAAGGGTGATACGG	ACTR8	ENSG00000113812	-1.77092831086042	[]	[]	-8	hSpCas9	negative selection	2913886
53882018	53882041	3	-	27260157	SF268	viability	AGGAGCAGCGCGGCGTGAAGCGG	ACTR8	ENSG00000113812	-0.291632007171386	[]	[]	-2	hSpCas9	negative selection	2916477
53881993	53882016	3	-	27260157	SF268	viability	CATCGTGCCCGCGCTGGTGCCGG	ACTR8	ENSG00000113812	0.0311483522719821	[]	[]	0	hSpCas9	negative selection	2916754
53881985	53882008	3	+	27260157	SF268	viability	CAGCGACTCCGGCACCAGCGCGG	ACTR8	ENSG00000113812	-0.484690780888896	[]	[]	-4	hSpCas9	negative selection	2916794
53882067	53882090	3	-	27260157	SF268	viability	GAGAAGGGTGATACGGAGAACGG	ACTR8	ENSG00000113812	-0.701251279280736	[]	[]	-5	hSpCas9	negative selection	2917451
53882028	53882051	3	-	27260157	SF268	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-0.771737475337025	[]	[]	-6	hSpCas9	negative selection	2925477
53882074	53882097	3	+	27260157	SF268	viability	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.8868152688449	[]	[]	-6	hSpCas9	negative selection	2945673
53882082	53882105	3	-	27260157	SF268	viability	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	-0.192189435382204	[]	[]	-1	hSpCas9	negative selection	2946199
53882052	53882075	3	-	27260157	SF268	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-5.22239431622284	[]	[]	-9	hSpCas9	negative selection	2946274
53881995	53882018	3	+	27260157	SF268	viability	GGCACCAGCGCGGGCACGATGGG	ACTR8	ENSG00000113812	-1.37741086943061	[]	[]	-7	hSpCas9	negative selection	2950313
53882082	53882105	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	-0.12533850165200958	[3,3]	[2,2]	-2	hSpCas9	positive selection	2968769
53879984	53880007	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.004488291800052613	[4,4]	[3,4]	0	hSpCas9	positive selection	2968770
53882052	53882075	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-0.6627202821304198	[1,1]	[0,0]	-7	hSpCas9	positive selection	2968771
53882028	53882051	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-0.38900788641367073	[3,3]	[2,2]	-5	hSpCas9	positive selection	2968772
53882082	53882105	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	-0.9425534118731024	[3,3]	[1,0]	-9	hSpCas9	positive selection	3036627
53879984	53880007	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.15410899006377016	[4,4]	[3,2]	-2	hSpCas9	positive selection	3036628
53882052	53882075	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-0.4844587268756464	[1,1]	[0,0]	-7	hSpCas9	positive selection	3036629
53882028	53882051	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-0.451200887553313	[3,3]	[3,0]	-6	hSpCas9	positive selection	3036630
53878408	53878431		-	24336571	A375	resistance to PLX after 7 days	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.3331662566170637	[12,12]	[10,8]	-8	hSpCas9	positive selection	3160177
53882074	53882097		+	24336571	A375	resistance to PLX after 7 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.2595471259492789	[10,9]	[8,7]	-7	hSpCas9	positive selection	3160188
53878352	53878375		+	24336571	A375	resistance to PLX after 7 days	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.2807742543227101	[4,6]	[3,5]	-8	hSpCas9	positive selection	3160199
53881974	53881997		+	24336571	A375	resistance to PLX after 7 days	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.21557779560104956	[9,11]	[11,12]	6	hSpCas9	positive selection	3160210
53881999	53882022		-	24336571	A375	resistance to PLX after 7 days	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.32067704894985327	[11,10]	[9,7]	-8	hSpCas9	positive selection	3160221
53878413	53878436		+	24336571	A375	resistance to PLX after 7 days	TTGCTTGATCCACCATTTTAAGG	ACTR8	ENSG00000113812	-0.2768240776909536	[10,12]	[8,8]	-7	hSpCas9	positive selection	3160231
53878408	53878431		-	24336571	A375	resistance to PLX after 14 days	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.9406584997125568	[11,14]	[3,1]	-9	hSpCas9	positive selection	3217970
53882074	53882097		+	24336571	A375	resistance to PLX after 14 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.16740835125148334	[9,9]	[2,4]	-2	hSpCas9	positive selection	3217981
53878352	53878375		+	24336571	A375	resistance to PLX after 14 days	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.3299138053995664	[4,5]	[2,2]	3	hSpCas9	positive selection	3217992
53881974	53881997		+	24336571	A375	resistance to PLX after 14 days	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.46466570024957665	[7,12]	[5,6]	4	hSpCas9	positive selection	3218003
53881999	53882022		-	24336571	A375	resistance to PLX after 14 days	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.15923723490761804	[8,11]	[4,2]	-2	hSpCas9	positive selection	3218014
53878413	53878436		+	24336571	A375	resistance to PLX after 14 days	TTGCTTGATCCACCATTTTAAGG	ACTR8	ENSG00000113812	-0.14002014304512947	[17,11]	[5,5]	-1	hSpCas9	positive selection	3218024
53878408	53878431		-	24336571	A375	viability after 7 days	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.3532239763101788	[10]	[12,12]	5	hSpCas9	negative selection	3275763
53882074	53882097		+	24336571	A375	viability after 7 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.6255724688073986	[16]	[10,9]	-7	hSpCas9	negative selection	3275774
53878352	53878375		+	24336571	A375	viability after 7 days	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.45762081265438415	[8]	[4,6]	-6	hSpCas9	negative selection	3275785
53881974	53881997		+	24336571	A375	viability after 7 days	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.4654614277968021	[15]	[9,11]	-6	hSpCas9	negative selection	3275796
53881999	53882022		-	24336571	A375	viability after 7 days	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.419451907816374	[16]	[11,10]	-5	hSpCas9	negative selection	3275807
53878413	53878436		+	24336571	A375	viability after 7 days	TTGCTTGATCCACCATTTTAAGG	ACTR8	ENSG00000113812	0.24292340955585356	[9]	[10,12]	3	hSpCas9	negative selection	3275817
53878408	53878431		-	24336571	A375	viability after 14 days	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.3981170824570346	[10]	[11,14]	5	hSpCas9	negative selection	3333556
53882074	53882097		+	24336571	A375	viability after 14 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.6071593753997601	[16]	[9,9]	-6	hSpCas9	negative selection	3333567
53878352	53878375		+	24336571	A375	viability after 14 days	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.6703233535368653	[8]	[4,5]	-7	hSpCas9	negative selection	3333578
53881974	53881997		+	24336571	A375	viability after 14 days	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.5279669778259248	[15]	[7,12]	-6	hSpCas9	negative selection	3333589
53881999	53882022		-	24336571	A375	viability after 14 days	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.551667669359824	[16]	[8,11]	-6	hSpCas9	negative selection	3333600
53878413	53878436		+	24336571	A375	viability after 14 days	TTGCTTGATCCACCATTTTAAGG	ACTR8	ENSG00000113812	0.6019965794145222	[9]	[17,11]	7	hSpCas9	negative selection	3333610
53881999	53882022	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.07435184428872642	[173,147]	[0,0]	0	hSpCas9	positive selection	3335456
53881974	53881997	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.5559939142244961	[213,235]	[0,0]	-4	hSpCas9	positive selection	3335457
53877654	53877677	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	3.9483881427844763	[112,94]	[0,19]	9	hSpCas9	positive selection	3335458
53877648	53877671	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.8301366298045043	[271,271]	[0,0]	-5	hSpCas9	positive selection	3354704
53878408	53878431	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.15206472469186658	[169,169]	[0,0]	-1	hSpCas9	positive selection	3354705
53878352	53878375	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	1.797894592808538	[43,43]	[0,0]	7	hSpCas9	positive selection	3354706
53882082	53882105	3	-	26780180	HT29	viability (Avana library 4 designs)	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	2.9326359807045	[]	[]	8	hSpCas9	negative selection	3404719
53879984	53880007	3	-	26780180	HT29	viability (Avana library 4 designs)	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	1.59246542980363	[]	[]	6	hSpCas9	negative selection	3404720
53882052	53882075	3	-	26780180	HT29	viability (Avana library 4 designs)	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	4.74686765796081	[]	[]	9	hSpCas9	negative selection	3404721
53882028	53882051	3	-	26780180	HT29	viability (Avana library 4 designs)	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	5.57821994247096	[]	[]	9	hSpCas9	negative selection	3404722
53882052	53882075	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-17.1888860473779	[]	[]	-9	hSpCas9	negative selection	3476393
53882082	53882105	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	-11.9298118182683	[]	[]	-8	hSpCas9	negative selection	3476394
53882028	53882051	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-6.1206483958976	[]	[]	-6	hSpCas9	negative selection	3476395
53879984	53880007	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.705144101090012	[]	[]	-1	hSpCas9	negative selection	3476396
53877311	53877334	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCAGTTAAATATTCACCCAGG	ACTR8	ENSG00000113812	-6.34882537144254	[]	[]	-6	hSpCas9	negative selection	3476397
53874344	53874367	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCTTTGTCTGGCATACGGAGG	ACTR8	ENSG00000113812	-13.3584393461914	[]	[]	-8	hSpCas9	negative selection	3476398
53882052	53882075	3	-	26780180	A375	viability (Avana lentiGuide)	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	25.0931365928845	[]	[]	9	hSpCas9	negative selection	3585052
53882082	53882105	3	-	26780180	A375	viability (Avana lentiGuide)	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	4.07163081176569	[]	[]	4	hSpCas9	negative selection	3585053
53882028	53882051	3	-	26780180	A375	viability (Avana lentiGuide)	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	38.6423788601167	[]	[]	9	hSpCas9	negative selection	3585054
53879984	53880007	3	-	26780180	A375	viability (Avana lentiGuide)	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-2.6980229488055	[]	[]	-5	hSpCas9	negative selection	3585055
53877311	53877334	3	-	26780180	A375	viability (Avana lentiGuide)	GGTCAGTTAAATATTCACCCAGG	ACTR8	ENSG00000113812	10.929590814169	[]	[]	7	hSpCas9	negative selection	3585056
53874344	53874367	3	-	26780180	A375	viability (Avana lentiGuide)	AGGCTTTGTCTGGCATACGGAGG	ACTR8	ENSG00000113812	25.5889624046266	[]	[]	9	hSpCas9	negative selection	3585057
53882052	53882075	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-2.418086764532054	[4]	[0,0]	-9	hSpCas9	positive selection	3693711
53882082	53882105	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	-0.24870560954599413	[5]	[4,3]	-4	hSpCas9	positive selection	3693712
53882028	53882051	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-0.9606195262965123	[5]	[3,1]	-8	hSpCas9	positive selection	3693713
53879984	53880007	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.4323628554480571	[5]	[3,4]	-6	hSpCas9	positive selection	3693714
53877311	53877334	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCAGTTAAATATTCACCCAGG	ACTR8	ENSG00000113812	-0.4711656970635263	[5]	[3,3]	-6	hSpCas9	positive selection	3693715
53874344	53874367	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCTTTGTCTGGCATACGGAGG	ACTR8	ENSG00000113812	-0.930927428833623	[5]	[2,2]	-8	hSpCas9	positive selection	3693716
53882052	53882075	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-1.2031311454640634	[5]	[0,2]	-9	hSpCas9	positive selection	3802318
53882082	53882105	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAATGACCCAGGCTGAGAAGGG	ACTR8	ENSG00000113812	0.11193437964897292	[5]	[4,4]	2	hSpCas9	positive selection	3802319
53882028	53882051	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-0.8734966537715454	[6]	[1,3]	-8	hSpCas9	positive selection	3802320
53879984	53880007	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	0.1735957588198427	[6]	[6,6]	4	hSpCas9	positive selection	3802321
53877311	53877334	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCAGTTAAATATTCACCCAGG	ACTR8	ENSG00000113812	-0.5927488691645053	[5]	[2,3]	-6	hSpCas9	positive selection	3802322
53874344	53874367	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCTTTGTCTGGCATACGGAGG	ACTR8	ENSG00000113812	-0.7580206929173863	[6]	[2,3]	-7	hSpCas9	positive selection	3802323
53878408	53878431	3	-	26780180	A375	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	1.2494018103676	[]	[]	6	hSpCas9	negative selection	3910920
53877654	53877677	3	-	26780180	A375	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	1.44800919386543	[]	[]	8	hSpCas9	negative selection	3910921
53878352	53878375	3	+	26780180	A375	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	1.15916411136747	[]	[]	6	hSpCas9	negative selection	3910922
53881974	53881997	3	+	26780180	A375	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	1.49170091244176	[]	[]	8	hSpCas9	negative selection	3910923
53881999	53882022	3	-	26780180	A375	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	1.37587803000051	[]	[]	7	hSpCas9	negative selection	3910924
53877648	53877671	3	+	26780180	A375	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	1.78841868396316	[]	[]	9	hSpCas9	negative selection	3910925
53878408	53878431	3	-	26780180	HT29	viability (GeCKOv2 library)	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	1.0033916947251	[]	[]	4	hSpCas9	negative selection	4018886
53877654	53877677	3	-	26780180	HT29	viability (GeCKOv2 library)	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	1.145313672884	[]	[]	5	hSpCas9	negative selection	4018887
53878352	53878375	3	+	26780180	HT29	viability (GeCKOv2 library)	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	1.73591905277362	[]	[]	8	hSpCas9	negative selection	4018888
53881974	53881997	3	+	26780180	HT29	viability (GeCKOv2 library)	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	2.53210689797875	[]	[]	9	hSpCas9	negative selection	4018889
53881999	53882022	3	-	26780180	HT29	viability (GeCKOv2 library)	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	1.4265491168244	[]	[]	7	hSpCas9	negative selection	4018890
53877648	53877671	3	+	26780180	HT29	viability (GeCKOv2 library)	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	1.27251244312069	[]	[]	6	hSpCas9	negative selection	4018891
53878408	53878431	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.3632327591964011	[3]	[2,1]	-7	hSpCas9	positive selection	4188245
53882074	53882097	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.13493488387572544	[3]	[1,1]	-3	hSpCas9	positive selection	4188256
53878352	53878375	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.4016283566590324	[3]	[1,1]	-7	hSpCas9	positive selection	4188267
53881974	53881997	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.2470012866194454	[3]	[3,2]	6	hSpCas9	positive selection	4188278
53881999	53882022	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.10887828970614008	[3]	[2,1]	-3	hSpCas9	positive selection	4188289
53878413	53878436	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGCTTGATCCACCATTTTAAGG	ACTR8	ENSG00000113812	0.04089324443744258	[3]	[2,2]	1	hSpCas9	positive selection	4188300
53878408	53878431	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.8893191629713334	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4252267
53882074	53882097	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.027927545628970207	[3]	[3,0,1,0]	0	hSpCas9	positive selection	4252278
53878352	53878375	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.7072111027597876	[1]	[3,0,1,0]	4	hSpCas9	positive selection	4252289
53881974	53881997	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.19964449070533094	[3]	[2,3,0,0]	1	hSpCas9	positive selection	4252300
53881999	53882022	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.2907551401561036	[4]	[0,3,1,0]	-4	hSpCas9	positive selection	4252311
53878413	53878436	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGCTTGATCCACCATTTTAAGG	ACTR8	ENSG00000113812	0.10744636860915523	[3]	[1,0,4,0]	0	hSpCas9	positive selection	4252322
53881999	53882022	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.3386757212084721	[3]	[2,1]	-6	hSpCas9	positive selection	4254377
53881974	53881997	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.310074324961762	[3]	[2,1]	-6	hSpCas9	positive selection	4254378
53877654	53877677	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.28312810917738884	[3]	[2,1]	-5	hSpCas9	positive selection	4254379
53877648	53877671	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	0.26816849261695436	[4]	[4,4]	5	hSpCas9	positive selection	4318660
53878408	53878431	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.03136714313066766	[2]	[2,1]	0	hSpCas9	positive selection	4318661
53878352	53878375	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.46194660674645954	[1]	[0,0]	-7	hSpCas9	positive selection	4318662
53878373	53878395	3	+	27760321	OCIAML3	viability	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	0.0026432813027373186	[529,430]	[354,399]	0	hSpCas9	negative selection	4375961
53879960	53879982	3	-	27760321	OCIAML3	viability	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	-0.2782071930837906	[410,273]	[207,230]	-3	hSpCas9	negative selection	4375962
53876005	53876027	3	-	27760321	OCIAML3	viability	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-1.3698133154077627	[530,409]	[113,176]	-8	hSpCas9	negative selection	4375963
53877366	53877388	3	-	27760321	OCIAML3	viability	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-2.527994895633221	[233,183]	[15,43]	-9	hSpCas9	negative selection	4375964
53877689	53877711	3	-	27760321	OCIAML3	viability	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	0.21588849870621574	[160,124]	[85,184]	2	hSpCas9	negative selection	4375965
53878373	53878395	3	+	27760321	OCIAML2	viability	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.5829013809956469	[529,430]	[233,289]	-6	hSpCas9	negative selection	4459424
53879960	53879982	3	-	27760321	OCIAML2	viability	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	-0.5921801542602884	[410,273]	[167,198]	-6	hSpCas9	negative selection	4459425
53876005	53876027	3	-	27760321	OCIAML2	viability	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-1.7824320040210049	[530,409]	[70,160]	-9	hSpCas9	negative selection	4459426
53877366	53877388	3	-	27760321	OCIAML2	viability	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-0.8220009218673046	[233,183]	[113,69]	-7	hSpCas9	negative selection	4459427
53877689	53877711	3	-	27760321	OCIAML2	viability	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	-0.40783460778759806	[160,124]	[105,60]	-5	hSpCas9	negative selection	4459428
53878373	53878395	3	+	27760321	MV411	viability	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.3308046302368003	[529,430]	[257,239]	-2	hSpCas9	negative selection	4542887
53879960	53879982	3	-	27760321	MV411	viability	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	-0.17463391288014518	[410,273]	[219,163]	-1	hSpCas9	negative selection	4542888
53876005	53876027	3	-	27760321	MV411	viability	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-1.0654072446081029	[530,409]	[4,360]	-6	hSpCas9	negative selection	4542889
53877366	53877388	3	-	27760321	MV411	viability	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	0.7750133180978431	[233,183]	[313,114]	6	hSpCas9	negative selection	4542890
53877689	53877711	3	-	27760321	MV411	viability	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	0.7851136644119071	[160,124]	[1,400]	6	hSpCas9	negative selection	4542891
53878373	53878395	3	+	27760321	HL60	viability	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.3270708302235785	[529,430]	[369,248]	-4	hSpCas9	negative selection	4626350
53879960	53879982	3	-	27760321	HL60	viability	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	0.36629849443155776	[410,273]	[352,358]	4	hSpCas9	negative selection	4626351
53876005	53876027	3	-	27760321	HL60	viability	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-1.0800094442361974	[530,409]	[212,145]	-8	hSpCas9	negative selection	4626352
53877366	53877388	3	-	27760321	HL60	viability	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-0.7236407258972808	[233,183]	[59,147]	-6	hSpCas9	negative selection	4626353
53877689	53877711	3	-	27760321	HL60	viability	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	-1.8439659109674833	[160,124]	[25,38]	-9	hSpCas9	negative selection	4626354
53878373	53878395	3	+	27760321	HT1080	viability	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-3.0676919847145103	[430,336]	[33,0]	-7	hSpCas9	negative selection	4709813
53879960	53879982	3	-	27760321	HT1080	viability	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	-6.602984146042197	[273,213]	[0,0]	-9	hSpCas9	negative selection	4709814
53876005	53876027	3	-	27760321	HT1080	viability	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-2.446093357767819	[409,319]	[19,33]	-7	hSpCas9	negative selection	4709815
53877366	53877388	3	-	27760321	HT1080	viability	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-2.1854082510272246	[183,143]	[0,28]	-6	hSpCas9	negative selection	4709816
53877689	53877711	3	-	27760321	HT1080	viability	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	-3.932761147127288	[124,97]	[0,4]	-8	hSpCas9	negative selection	4709817
53878373	53878395	3	+	27760321	HT29	viability after 7 days	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.5063526209862556	[430,336]	[310,342,381]	-6	hSpCas9	negative selection	4793276
53879960	53879982	3	-	27760321	HT29	viability after 7 days	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	0.7404920950639038	[273,213]	[595,621,368]	9	hSpCas9	negative selection	4793277
53876005	53876027	3	-	27760321	HT29	viability after 7 days	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	0.1654680258504501	[409,319]	[664,375,555]	2	hSpCas9	negative selection	4793278
53877366	53877388	3	-	27760321	HT29	viability after 7 days	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	0.16418652751023088	[183,143]	[146,316,231]	2	hSpCas9	negative selection	4793279
53877689	53877711	3	-	27760321	HT29	viability after 7 days	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	0.4521694150661686	[124,97]	[145,330,106]	7	hSpCas9	negative selection	4793280
53878373	53878395	3	+	27760321	HT29	viability after 25 days	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.6270274786173669	[430,336]	[254,236,370]	-5	hSpCas9	negative selection	4876739
53879960	53879982	3	-	27760321	HT29	viability after 25 days	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	-0.730342769678245	[273,213]	[150,134,224]	-6	hSpCas9	negative selection	4876740
53876005	53876027	3	-	27760321	HT29	viability after 25 days	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-4.728584876941343	[409,319]	[19,18,6]	-9	hSpCas9	negative selection	4876741
53877366	53877388	3	-	27760321	HT29	viability after 25 days	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.3783871474740337	[183,143]	[65,5,152]	-7	hSpCas9	negative selection	4876742
53877689	53877711	3	-	27760321	HT29	viability after 25 days	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	-1.4242577808728485	[124,97]	[4,32,113]	-7	hSpCas9	negative selection	4876743
53878373	53878395	3	+	27760321	HT29	viability after 22 days	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.39746711907885235	[430,336]	[314,334,361]	-4	hSpCas9	negative selection	4960202
53879960	53879982	3	-	27760321	HT29	viability after 22 days	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	-0.5704334108857481	[273,213]	[194,157,216]	-5	hSpCas9	negative selection	4960203
53876005	53876027	3	-	27760321	HT29	viability after 22 days	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-2.8802039573207248	[409,319]	[53,62,54]	-8	hSpCas9	negative selection	4960204
53877366	53877388	3	-	27760321	HT29	viability after 22 days	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-0.5704605372002722	[183,143]	[229,54,94]	-5	hSpCas9	negative selection	4960205
53877689	53877711	3	-	27760321	HT29	viability after 22 days	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	-0.9218012800608286	[124,97]	[4,119,80]	-6	hSpCas9	negative selection	4960206
53878373	53878395	3	+	27760321	HT29	viability after 19 days	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.6158875134663869	[430,336]	[232,226,389]	-5	hSpCas9	negative selection	5043665
53879960	53879982	3	-	27760321	HT29	viability after 19 days	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	-0.6531489990912147	[273,213]	[288,132,123]	-5	hSpCas9	negative selection	5043666
53876005	53876027	3	-	27760321	HT29	viability after 19 days	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-1.5055993259338571	[409,319]	[191,222,34]	-7	hSpCas9	negative selection	5043667
53877366	53877388	3	-	27760321	HT29	viability after 19 days	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.1083535501177828	[183,143]	[105,70,85]	-7	hSpCas9	negative selection	5043668
53877689	53877711	3	-	27760321	HT29	viability after 19 days	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	-0.884484159873788	[124,97]	[13,78,106]	-6	hSpCas9	negative selection	5043669
53878373	53878395	3	+	27760321	HT29	viability after 16 days	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.49905004827626476	[430,336]	[348,275,291]	-5	hSpCas9	negative selection	5127128
53879960	53879982	3	-	27760321	HT29	viability after 16 days	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	0.1937968309444248	[273,213]	[376,151,417]	2	hSpCas9	negative selection	5127129
53876005	53876027	3	-	27760321	HT29	viability after 16 days	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-1.3248448424943764	[409,319]	[75,231,170]	-7	hSpCas9	negative selection	5127130
53877366	53877388	3	-	27760321	HT29	viability after 16 days	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.1055837636023191	[183,143]	[81,66,106]	-7	hSpCas9	negative selection	5127131
53877689	53877711	3	-	27760321	HT29	viability after 16 days	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	-0.8738079396790672	[124,97]	[93,18,94]	-6	hSpCas9	negative selection	5127132
53878373	53878395	3	+	27760321	HT29	viability after 13 days	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.7287698199779574	[430,336]	[356,226,224]	-6	hSpCas9	negative selection	5210591
53879960	53879982	3	-	27760321	HT29	viability after 13 days	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	0.4018837005604944	[273,213]	[225,533,362]	5	hSpCas9	negative selection	5210592
53876005	53876027	3	-	27760321	HT29	viability after 13 days	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-1.2970492442515373	[409,319]	[127,181,204]	-8	hSpCas9	negative selection	5210593
53877366	53877388	3	-	27760321	HT29	viability after 13 days	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.142129220181067	[183,143]	[70,106,80]	-7	hSpCas9	negative selection	5210594
53877689	53877711	3	-	27760321	HT29	viability after 13 days	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	-0.3520311761830195	[124,97]	[125,92,85]	-4	hSpCas9	negative selection	5210595
53878373	53878395	3	+	27760321	HT29	viability after 10 days	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-0.40524583900446653	[430,336]	[305,423,357]	-5	hSpCas9	negative selection	5294054
53879960	53879982	3	-	27760321	HT29	viability after 10 days	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	0.28316056556862323	[273,213]	[239,566,311]	4	hSpCas9	negative selection	5294055
53876005	53876027	3	-	27760321	HT29	viability after 10 days	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-0.41861635035952827	[409,319]	[468,267,284]	-5	hSpCas9	negative selection	5294056
53877366	53877388	3	-	27760321	HT29	viability after 10 days	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	0.22385481061505164	[183,143]	[333,126,252]	3	hSpCas9	negative selection	5294057
53877689	53877711	3	-	27760321	HT29	viability after 10 days	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	0.24395921209346771	[124,97]	[164,210,120]	3	hSpCas9	negative selection	5294058
53878373	53878395	3	+	27760321	MOLM13	viability	GGAATGCGTCTTGTACCATTGG	ACTR8	ENSG00000113812	-1.131978326401543	[529,430]	[128,117]	-6	hSpCas9	negative selection	5377517
53879960	53879982	3	-	27760321	MOLM13	viability	GCCCCTATACAAGGACAGTTGG	ACTR8	ENSG00000113812	-1.0803725459338076	[410,273]	[80,97]	-6	hSpCas9	negative selection	5377518
53876005	53876027	3	-	27760321	MOLM13	viability	GCACGTGTATTGTAGACGTTGG	ACTR8	ENSG00000113812	-1.6097398898647095	[530,409]	[0,158]	-7	hSpCas9	negative selection	5377519
53877366	53877388	3	-	27760321	MOLM13	viability	GCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.0680208284370019	[233,183]	[70,42]	-6	hSpCas9	negative selection	5377520
53877689	53877711	3	-	27760321	MOLM13	viability	TCACTGTTCGGGAAATAAGTGG	ACTR8	ENSG00000113812	-2.647988100586221	[160,124]	[8,15]	-8	hSpCas9	negative selection	5377521
53881926	53881949	3	+	27661255	K562	viability	GCAGCGGAGGACCCAAGCAAGGG	ACTR8	ENSG00000113812	-0.15874520835492967	[218,229]	[173,148]	-5	dCas9-KRAB	negative selection	5460791
53882092	53882115	3	-	27661255	K562	viability	GTCTCCGGCCATAATGACCCAGG	ACTR8	ENSG00000113812	-0.7759186501974976	[701,655]	[375,266]	-8	dCas9-KRAB	negative selection	5460792
53882154	53882177	3	-	27661255	K562	viability	GCGCGGTGGCCCTTCCATCCCGG	ACTR8	ENSG00000113812	-0.4042070311732413	[262,351]	[202,168]	-7	dCas9-KRAB	negative selection	5460793
53881999	53882022	3	-	27260156	BXPC3	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.3466498321408835	[683]	[757,836,949,1135]	7	hSpCas9	negative selection	5526837
53881974	53881997	3	+	27260156	BXPC3	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.04167778575910874	[834]	[741,915,893,1073]	0	hSpCas9	negative selection	5526838
53877654	53877677	3	-	27260156	BXPC3	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.13117087102283725	[610]	[589,524,508,723]	-3	hSpCas9	negative selection	5526839
53877648	53877671	3	+	27260156	BXPC3	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.9223283193200362	[1353]	[634,860,745,745]	-9	hSpCas9	negative selection	5591120
53878408	53878431	3	-	27260156	BXPC3	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.039438715945281366	[375]	[326,319,431,469]	-1	hSpCas9	negative selection	5591121
53878352	53878375	3	+	27260156	BXPC3	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.20139434616119534	[173]	[118,149,230,134]	-4	hSpCas9	negative selection	5591122
53881999	53882022	3	-	27260156	A673	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.04711371137977771	[683]	[892,880,752,871]	1	hSpCas9	negative selection	5648088
53881974	53881997	3	+	27260156	A673	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.06974677213096958	[834]	[923,844,1096,950]	-2	hSpCas9	negative selection	5648089
53877654	53877677	3	-	27260156	A673	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.22762167284744492	[610]	[729,687,584,505]	-5	hSpCas9	negative selection	5648090
53877648	53877671	3	+	27260156	A673	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.464169635716277	[1353]	[1244,1065,1112,1305]	-8	hSpCas9	negative selection	5712371
53878408	53878431	3	-	27260156	A673	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.14725432568392416	[375]	[417,427,373,410]	-4	hSpCas9	negative selection	5712372
53878352	53878375	3	+	27260156	A673	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.1566169781101543	[173]	[173,203,158,211]	-4	hSpCas9	negative selection	5712373
53881999	53882022	3	-	27260156	A375	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.22110986590769	[683]	[904,1079,836,920]	3	hSpCas9	negative selection	5769339
53881974	53881997	3	+	27260156	A375	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.28839807671292783	[834]	[1430,1273,1135,959]	4	hSpCas9	negative selection	5769340
53877654	53877677	3	-	27260156	A375	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.875705099107468	[610]	[339,566,304,368]	-8	hSpCas9	negative selection	5769341
53877648	53877671	3	+	27260156	A375	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.043396081136736	[1353]	[635,1262,641,611]	-8	hSpCas9	negative selection	5833622
53878408	53878431	3	-	27260156	A375	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.12286433855804768	[375]	[420,419,340,428]	-2	hSpCas9	negative selection	5833623
53878352	53878375	3	+	27260156	A375	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.2920737998184282	[173]	[165,254,137,121]	-4	hSpCas9	negative selection	5833624
53881999	53882022	3	-	27260156	COLO741	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.14557222015202387	[683]	[934,959,997]	3	hSpCas9	negative selection	5890590
53881974	53881997	3	+	27260156	COLO741	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.1484164973734894	[834]	[1294,1116,1144]	3	hSpCas9	negative selection	5890591
53877654	53877677	3	-	27260156	COLO741	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.38310113213097213	[610]	[587,667,541]	-7	hSpCas9	negative selection	5890592
53877648	53877671	3	+	27260156	COLO741	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.5318093264355584	[1353]	[1250,1217,1127]	-8	hSpCas9	negative selection	5954873
53878408	53878431	3	-	27260156	COLO741	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.15781898526885357	[375]	[596,454,557]	3	hSpCas9	negative selection	5954874
53878352	53878375	3	+	27260156	COLO741	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.08698717970127245	[173]	[181,230,211]	-2	hSpCas9	negative selection	5954875
53881999	53882022	3	-	27260156	CAL120	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.05335888852590093	[683]	[918,887,670]	-1	hSpCas9	negative selection	6011841
53881974	53881997	3	+	27260156	CAL120	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.16190026837630334	[834]	[1180,833,810]	-2	hSpCas9	negative selection	6011842
53877654	53877677	3	-	27260156	CAL120	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.40503502702826294	[610]	[603,611,511]	-5	hSpCas9	negative selection	6011843
53877648	53877671	3	+	27260156	CAL120	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.1101116724470974	[1353]	[849,622,876]	-9	hSpCas9	negative selection	6076124
53878408	53878431	3	-	27260156	CAL120	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.07274673686368044	[375]	[472,329,666]	1	hSpCas9	negative selection	6076125
53878352	53878375	3	+	27260156	CAL120	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-1.4436139955547258	[173]	[44,76,110]	-9	hSpCas9	negative selection	6076126
53881999	53882022	3	-	27260156	CADOES1	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.2748452254068373	[683]	[766,738,639,938]	4	hSpCas9	negative selection	6133092
53881974	53881997	3	+	27260156	CADOES1	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.11038991165634593	[834]	[686,828,537,827]	-2	hSpCas9	negative selection	6133093
53877654	53877677	3	-	27260156	CADOES1	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.23355413661471075	[610]	[346,579,519,486]	-4	hSpCas9	negative selection	6133094
53877648	53877671	3	+	27260156	CADOES1	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.3987122357200903	[1353]	[1041,809,1123,839]	-6	hSpCas9	negative selection	6197375
53878408	53878431	3	-	27260156	CADOES1	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.00849053586970544	[375]	[374,362,293,358]	0	hSpCas9	negative selection	6197376
53878352	53878375	3	+	27260156	CADOES1	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.10730586313450008	[173]	[240,172,137,143]	1	hSpCas9	negative selection	6197377
53881999	53882022	3	-	27260156	EWS502	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.11746621169077809	[683]	[773,650,709,1028]	2	hSpCas9	negative selection	6254343
53881974	53881997	3	+	27260156	EWS502	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.0981821891991943	[834]	[680,776,1060,803]	-2	hSpCas9	negative selection	6254344
53877654	53877677	3	-	27260156	EWS502	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.330375150803389	[610]	[489,683,438,432]	-5	hSpCas9	negative selection	6254345
53877648	53877671	3	+	27260156	EWS502	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.8380988746213721	[1353]	[650,823,887,865]	-8	hSpCas9	negative selection	6318626
53878408	53878431	3	-	27260156	EWS502	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.019601202034431997	[375]	[423,430,340,365]	0	hSpCas9	negative selection	6318627
53878352	53878375	3	+	27260156	EWS502	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.1876422407718683	[173]	[249,171,160,254]	3	hSpCas9	negative selection	6318628
53881999	53882022	3	-	27260156	EW8	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.055992471222820694	[683]	[704,520,446,491]	-1	hSpCas9	negative selection	6375594
53881974	53881997	3	+	27260156	EW8	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.04808062380109568	[834]	[684,652,603,685]	-1	hSpCas9	negative selection	6375595
53877654	53877677	3	-	27260156	EW8	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.5046423536023898	[610]	[488,328,280,322]	-7	hSpCas9	negative selection	6375596
53877648	53877671	3	+	27260156	EW8	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.4657157813209467	[1353]	[733,831,778,826]	-7	hSpCas9	negative selection	6439877
53878408	53878431	3	-	27260156	EW8	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.3924109326146267	[375]	[371,395,468,346]	7	hSpCas9	negative selection	6439878
53878352	53878375	3	+	27260156	EW8	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.08599936553509302	[173]	[191,108,117,188]	1	hSpCas9	negative selection	6439879
53881999	53882022	3	-	27260156	CORL105	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.15581465962013707	[683]	[1146,692,1042,721]	3	hSpCas9	negative selection	6496845
53881974	53881997	3	+	27260156	CORL105	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.06159144308379949	[834]	[1075,823,1033,834]	-1	hSpCas9	negative selection	6496846
53877654	53877677	3	-	27260156	CORL105	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.6589750005847002	[610]	[325,356,574,569]	-8	hSpCas9	negative selection	6496847
53877648	53877671	3	+	27260156	CORL105	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.8488412752923016	[1353]	[813,915,948,848]	-9	hSpCas9	negative selection	6561128
53878408	53878431	3	-	27260156	CORL105	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.43833883727734646	[375]	[281,419,448,164]	-7	hSpCas9	negative selection	6561129
53878352	53878375	3	+	27260156	CORL105	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.7677713010172069	[173]	[68,130,185,100]	-8	hSpCas9	negative selection	6561130
53881999	53882022	3	-	27260156	HS294T	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.9441627792059297	[683]	[352,632,477,594]	9	hSpCas9	negative selection	6618096
53881974	53881997	3	+	27260156	HS294T	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.1645762986119732	[834]	[335,437,300,372]	2	hSpCas9	negative selection	6618097
53877654	53877677	3	-	27260156	HS294T	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.2514408148145457	[610]	[79,192,307,228]	-4	hSpCas9	negative selection	6618098
53877648	53877671	3	+	27260156	HS294T	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.9031832643735922	[1353]	[236,206,308,390]	-8	hSpCas9	negative selection	6682379
53878408	53878431	3	-	27260156	HS294T	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.10106673845869138	[375]	[86,182,157,209]	1	hSpCas9	negative selection	6682380
53878352	53878375	3	+	27260156	HS294T	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.7173899295506855	[173]	[55,235,70,73]	8	hSpCas9	negative selection	6682381
53881999	53882022	3	-	27260156	HCC44	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.17900766531515155	[683]	[982,797,853,877]	3	hSpCas9	negative selection	6739347
53881974	53881997	3	+	27260156	HCC44	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.2062061912084029	[834]	[1367,654,1561,937]	3	hSpCas9	negative selection	6739348
53877654	53877677	3	-	27260156	HCC44	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.6891153552823784	[610]	[619,338,530,273]	-7	hSpCas9	negative selection	6739349
53877648	53877671	3	+	27260156	HCC44	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.9073293029422292	[1353]	[761,733,843,926]	-8	hSpCas9	negative selection	6803630
53878408	53878431	3	-	27260156	HCC44	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.001834419782558716	[375]	[387,298,497,537]	0	hSpCas9	negative selection	6803631
53878352	53878375	3	+	27260156	HCC44	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.2712614300433984	[173]	[533,112,231,116]	4	hSpCas9	negative selection	6803632
53881999	53882022	3	-	27260156	G402	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.41475446546097217	[683]	[932,1595,1097,834]	5	hSpCas9	negative selection	6860598
53881974	53881997	3	+	27260156	G402	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.1836842643970028	[834]	[1430,920,1497,816]	2	hSpCas9	negative selection	6860599
53877654	53877677	3	-	27260156	G402	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.7337830382881163	[610]	[328,398,331,698]	-7	hSpCas9	negative selection	6860600
53877648	53877671	3	+	27260156	G402	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.3094258398560987	[1353]	[918,593,662,526]	-9	hSpCas9	negative selection	6924881
53878408	53878431	3	-	27260156	G402	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.22316290016173235	[375]	[263,460,353,472]	-3	hSpCas9	negative selection	6924882
53878352	53878375	3	+	27260156	G402	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.09893983171777232	[173]	[268,385,170,103]	1	hSpCas9	negative selection	6924883
53881999	53882022	3	-	27260156	L33	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.09803223624258506	[683]	[676,279,604,608]	2	hSpCas9	negative selection	6981849
53881974	53881997	3	+	27260156	L33	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.07549392329162363	[834]	[897,307,528,676]	-2	hSpCas9	negative selection	6981850
53877654	53877677	3	-	27260156	L33	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	0.18680719807585028	[610]	[673,281,451,700]	4	hSpCas9	negative selection	6981851
53877648	53877671	3	+	27260156	L33	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.1664012217269546	[1353]	[1239,538,734,1100]	-4	hSpCas9	negative selection	7046132
53878408	53878431	3	-	27260156	L33	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.14750442866619423	[375]	[345,136,225,317]	-3	hSpCas9	negative selection	7046133
53878352	53878375	3	+	27260156	L33	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.049438100761162396	[173]	[128,60,104,227]	-1	hSpCas9	negative selection	7046134
53881999	53882022	3	-	27260156	K562	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.29535925259823104	[683]	[905,453,1101,536]	3	hSpCas9	negative selection	7103100
53881974	53881997	3	+	27260156	K562	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.11787925794367915	[834]	[608,898,685,554]	-1	hSpCas9	negative selection	7103101
53877654	53877677	3	-	27260156	K562	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.19799109730779269	[610]	[437,764,411,305]	-2	hSpCas9	negative selection	7103102
53877648	53877671	3	+	27260156	K562	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.7806130590218099	[1353]	[845,673,684,610]	-7	hSpCas9	negative selection	7167383
53878408	53878431	3	-	27260156	K562	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.03335813425554368	[375]	[294,421,334,260]	0	hSpCas9	negative selection	7167384
53878352	53878375	3	+	27260156	K562	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.01463805212072078	[173]	[361,142,58,83]	0	hSpCas9	negative selection	7167385
53881999	53882022	3	-	27260156	HT29	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.10093604045526777	[683]	[1012,762,572,764]	-2	hSpCas9	negative selection	7224351
53881974	53881997	3	+	27260156	HT29	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.09167286432919419	[834]	[1384,1161,1008,824]	1	hSpCas9	negative selection	7224352
53877654	53877677	3	-	27260156	HT29	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.9389528995701288	[610]	[369,436,482,273]	-8	hSpCas9	negative selection	7224353
53877648	53877671	3	+	27260156	HT29	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.0614583029876168	[1353]	[927,654,730,828]	-9	hSpCas9	negative selection	7288634
53878408	53878431	3	-	27260156	HT29	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.09541264088585116	[375]	[564,507,416,256]	-2	hSpCas9	negative selection	7288635
53878352	53878375	3	+	27260156	HT29	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.1368285415558801	[173]	[279,172,197,129]	-3	hSpCas9	negative selection	7288636
53881999	53882022	3	-	27260156	MHHES1	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.036084427366348204	[683]	[948,904,752,607]	0	hSpCas9	negative selection	7345602
53881974	53881997	3	+	27260156	MHHES1	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.28215669579132496	[834]	[1062,685,783,607]	-5	hSpCas9	negative selection	7345603
53877654	53877677	3	-	27260156	MHHES1	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.11568058549591492	[610]	[696,616,561,650]	-2	hSpCas9	negative selection	7345604
53877648	53877671	3	+	27260156	MHHES1	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.3904557236456443	[1353]	[1462,1337,994,936]	-6	hSpCas9	negative selection	7409885
53878408	53878431	3	-	27260156	MHHES1	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.09244061517445418	[375]	[762,433,491,201]	1	hSpCas9	negative selection	7409886
53878352	53878375	3	+	27260156	MHHES1	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.03029253802678822	[173]	[197,217,194,188]	0	hSpCas9	negative selection	7409887
53881999	53882022	3	-	27260156	MEWO	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.09233915412246341	[683]	[764,589,707]	2	hSpCas9	negative selection	7466853
53881974	53881997	3	+	27260156	MEWO	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.02467293947187099	[834]	[882,782,734]	0	hSpCas9	negative selection	7466854
53877654	53877677	3	-	27260156	MEWO	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	0.19178447402982862	[610]	[763,668,546]	4	hSpCas9	negative selection	7466855
53877648	53877671	3	+	27260156	MEWO	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.20794900449683995	[1353]	[1133,914,1248]	-4	hSpCas9	negative selection	7531136
53878408	53878431	3	-	27260156	MEWO	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.023646057820244037	[375]	[361,380,297]	0	hSpCas9	negative selection	7531137
53878352	53878375	3	+	27260156	MEWO	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.34667027469682643	[173]	[263,208,158]	7	hSpCas9	negative selection	7531138
53881999	53882022	3	-	27260156	LNCAPCLONEFGC	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.012540895001826424	[683]	[546,648,596,659]	0	hSpCas9	negative selection	7588104
53881974	53881997	3	+	27260156	LNCAPCLONEFGC	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.06644916800477085	[834]	[629,702,955,911]	1	hSpCas9	negative selection	7588105
53877654	53877677	3	-	27260156	LNCAPCLONEFGC	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.2637178455817901	[610]	[555,378,559,366]	-4	hSpCas9	negative selection	7588106
53877648	53877671	3	+	27260156	LNCAPCLONEFGC	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.7378720320575837	[1353]	[589,686,786,890]	-8	hSpCas9	negative selection	7652387
53878408	53878431	3	-	27260156	LNCAPCLONEFGC	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.3706447146998204	[375]	[359,473,611,339]	6	hSpCas9	negative selection	7652388
53878352	53878375	3	+	27260156	LNCAPCLONEFGC	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.31596536217339977	[173]	[222,193,166,195]	5	hSpCas9	negative selection	7652389
53881999	53882022	3	-	27260156	PANC0327	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.47153310060899467	[683]	[543,1063,1001,706]	7	hSpCas9	negative selection	7709355
53881974	53881997	3	+	27260156	PANC0327	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.4505290366406617	[834]	[1209,1010,1135,713]	6	hSpCas9	negative selection	7709356
53877654	53877677	3	-	27260156	PANC0327	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.2805634720257642	[610]	[201,352,437,785]	-4	hSpCas9	negative selection	7709357
53877648	53877671	3	+	27260156	PANC0327	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.2642820486800903	[1353]	[799,293,506,452]	-9	hSpCas9	negative selection	7773638
53878408	53878431	3	-	27260156	PANC0327	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.7150260523042395	[375]	[659,537,772,232]	8	hSpCas9	negative selection	7773639
53878352	53878375	3	+	27260156	PANC0327	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.5578345273854912	[173]	[37,86,213,77]	-7	hSpCas9	negative selection	7773640
53881999	53882022	3	-	27260156	NCIH2009	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.34019091303648963	[683]	[1365,1274,1015]	5	hSpCas9	negative selection	7830606
53881974	53881997	3	+	27260156	NCIH2009	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.10553567309648637	[834]	[1604,1007,1223]	1	hSpCas9	negative selection	7830607
53877654	53877677	3	-	27260156	NCIH2009	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.5865510287809397	[610]	[875,527,361]	-6	hSpCas9	negative selection	7830608
53877648	53877671	3	+	27260156	NCIH2009	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.1735921131004667	[1353]	[951,943,638]	-8	hSpCas9	negative selection	7894889
53878408	53878431	3	-	27260156	NCIH2009	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.0464489323121452	[375]	[445,352,811]	0	hSpCas9	negative selection	7894890
53878352	53878375	3	+	27260156	NCIH2009	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.9696535229402494	[173]	[135,98,139]	-8	hSpCas9	negative selection	7894891
53881999	53882022	3	-	27260156	NCIH1373	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	-0.017204842554488176	[683]	[669,632,754,257]	0	hSpCas9	negative selection	7951857
53881974	53881997	3	+	27260156	NCIH1373	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.15379070818220275	[834]	[1200,1144,813,266]	1	hSpCas9	negative selection	7951858
53877654	53877677	3	-	27260156	NCIH1373	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.38518926061853515	[610]	[456,412,693,138]	-4	hSpCas9	negative selection	7951859
53877648	53877671	3	+	27260156	NCIH1373	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.2325016515383396	[1353]	[480,901,719,106]	-8	hSpCas9	negative selection	8016140
53878408	53878431	3	-	27260156	NCIH1373	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.138113681828955	[375]	[340,377,448,180]	1	hSpCas9	negative selection	8016141
53878352	53878375	3	+	27260156	NCIH1373	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.17190545469612584	[173]	[67,142,86,103]	-2	hSpCas9	negative selection	8016142
53881999	53882022	3	-	27260156	PATU8902	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.0530499657407435	[683]	[861,1241,875,997]	0	hSpCas9	negative selection	8073108
53881974	53881997	3	+	27260156	PATU8902	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.20084164004511817	[834]	[1943,1195,1250,906]	2	hSpCas9	negative selection	8073109
53877654	53877677	3	-	27260156	PATU8902	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-1.0698714310209418	[610]	[598,298,452,230]	-7	hSpCas9	negative selection	8073110
53877648	53877671	3	+	27260156	PATU8902	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.9674374620294636	[1353]	[772,998,808,1358]	-7	hSpCas9	negative selection	8137391
53878408	53878431	3	-	27260156	PATU8902	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.32913848103777893	[375]	[516,719,354,1176]	3	hSpCas9	negative selection	8137392
53878352	53878375	3	+	27260156	PATU8902	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.4018854602358637	[173]	[265,539,182,326]	4	hSpCas9	negative selection	8137393
53881999	53882022	3	-	27260156	PANC1	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.08170787983216277	[683]	[605,759,593,555]	1	hSpCas9	negative selection	8194359
53881974	53881997	3	+	27260156	PANC1	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.0762178145717537	[834]	[774,909,748,629]	1	hSpCas9	negative selection	8194360
53877654	53877677	3	-	27260156	PANC1	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.705013888923854	[610]	[254,569,228,285]	-7	hSpCas9	negative selection	8194361
53877648	53877671	3	+	27260156	PANC1	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.1826185184582898	[1353]	[507,778,645,213]	-9	hSpCas9	negative selection	8258642
53878408	53878431	3	-	27260156	PANC1	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.1399557904135306	[375]	[300,316,494,306]	2	hSpCas9	negative selection	8258643
53878352	53878375	3	+	27260156	PANC1	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.04810362936361989	[173]	[129,160,148,173]	0	hSpCas9	negative selection	8258644
53881999	53882022	3	-	27260156	PANC0813	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.13766155659446855	[683]	[764,829,1028,898]	2	hSpCas9	negative selection	8315610
53881974	53881997	3	+	27260156	PANC0813	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.011566846503096584	[834]	[1151,895,927,932]	0	hSpCas9	negative selection	8315611
53877654	53877677	3	-	27260156	PANC0813	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-1.017165029358988	[610]	[460,283,231,444]	-8	hSpCas9	negative selection	8315612
53877648	53877671	3	+	27260156	PANC0813	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.4344633026172526	[1353]	[790,481,505,591]	-9	hSpCas9	negative selection	8379893
53878408	53878431	3	-	27260156	PANC0813	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.6939293904925244	[375]	[228,194,284,372]	-7	hSpCas9	negative selection	8379894
53878352	53878375	3	+	27260156	PANC0813	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.30183885155947254	[173]	[285,148,130,110]	-5	hSpCas9	negative selection	8379895
53881999	53882022	3	-	27260156	RDES	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.22514387835710248	[683]	[748,855,904,1229]	3	hSpCas9	negative selection	8436861
53881974	53881997	3	+	27260156	RDES	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.3180992343782888	[834]	[998,1098,1325,1418]	5	hSpCas9	negative selection	8436862
53877654	53877677	3	-	27260156	RDES	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.07330372971641491	[610]	[596,680,693,696]	-1	hSpCas9	negative selection	8436863
53877648	53877671	3	+	27260156	RDES	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.5393845526497454	[1353]	[947,901,1135,1354]	-7	hSpCas9	negative selection	8501144
53878408	53878431	3	-	27260156	RDES	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.22444510593887498	[375]	[450,532,486,547]	3	hSpCas9	negative selection	8501145
53878352	53878375	3	+	27260156	RDES	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.05372831355796648	[173]	[142,174,178,368]	0	hSpCas9	negative selection	8501146
53881999	53882022	3	-	27260156	PC3	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.007692549368904067	[683]	[429,740,1135,649]	0	hSpCas9	negative selection	8558112
53881974	53881997	3	+	27260156	PC3	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.2668220338737305	[834]	[718,888,1312,1235]	6	hSpCas9	negative selection	8558113
53877654	53877677	3	-	27260156	PC3	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	0.19362080711468183	[610]	[492,582,1014,845]	4	hSpCas9	negative selection	8558114
53877648	53877671	3	+	27260156	PC3	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.1806262043324347	[1353]	[679,1062,2194,1348]	-4	hSpCas9	negative selection	8622395
53878408	53878431	3	-	27260156	PC3	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.08253804653559282	[375]	[235,418,490,514]	1	hSpCas9	negative selection	8622396
53878352	53878375	3	+	27260156	PC3	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.29291395862697955	[173]	[91,62,253,216]	-6	hSpCas9	negative selection	8622397
53881999	53882022	3	-	27260156	PATU8988T	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.10668155201685403	[683]	[684,827,775,554]	1	hSpCas9	negative selection	8679363
53881974	53881997	3	+	27260156	PATU8988T	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.09364558977022153	[834]	[777,908,964,788]	1	hSpCas9	negative selection	8679364
53877654	53877677	3	-	27260156	PATU8988T	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.09064831501327919	[610]	[657,569,533,448]	-1	hSpCas9	negative selection	8679365
53877648	53877671	3	+	27260156	PATU8988T	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.8464504438354634	[1353]	[781,628,622,880]	-8	hSpCas9	negative selection	8743646
53878408	53878431	3	-	27260156	PATU8988T	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.37309028700340136	[375]	[317,444,646,466]	6	hSpCas9	negative selection	8743647
53878352	53878375	3	+	27260156	PATU8988T	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.6895475137228544	[173]	[252,386,54,414]	9	hSpCas9	negative selection	8743648
53881999	53882022	3	-	27260156	T47D	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.12285613664541806	[683]	[894,871,889,810]	2	hSpCas9	negative selection	8800614
53881974	53881997	3	+	27260156	T47D	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.138029198765795	[834]	[1010,975,1103,1201]	3	hSpCas9	negative selection	8800615
53877654	53877677	3	-	27260156	T47D	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	0.32375661179413723	[610]	[909,809,923,926]	7	hSpCas9	negative selection	8800616
53877648	53877671	3	+	27260156	T47D	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.02132897460950267	[1353]	[1728,1401,1617,1477]	0	hSpCas9	negative selection	8864897
53878408	53878431	3	-	27260156	T47D	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.24650246224293076	[375]	[563,505,495,513]	5	hSpCas9	negative selection	8864898
53878352	53878375	3	+	27260156	T47D	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.004426807819630341	[173]	[202,191,211,201]	0	hSpCas9	negative selection	8864899
53881999	53882022	3	-	27260156	SU8686	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.19984260863120673	[683]	[747,657,878,859]	3	hSpCas9	negative selection	8921865
53881974	53881997	3	+	27260156	SU8686	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.11030048941795101	[834]	[570,588,877,1131]	-2	hSpCas9	negative selection	8921866
53877654	53877677	3	-	27260156	SU8686	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.98545997807187	[610]	[282,301,274,374]	-8	hSpCas9	negative selection	8921867
53877648	53877671	3	+	27260156	SU8686	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-1.6541936209607888	[1353]	[505,430,365,380]	-9	hSpCas9	negative selection	8986148
53878408	53878431	3	-	27260156	SU8686	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	-0.4218887857425455	[375]	[250,256,271,347]	-6	hSpCas9	negative selection	8986149
53878352	53878375	3	+	27260156	SU8686	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.383334082458451	[173]	[156,115,152,95]	-6	hSpCas9	negative selection	8986150
53881999	53882022	3	-	27260156	SKES1	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.2643124495757977	[683]	[884,813,858,729]	5	hSpCas9	negative selection	9043116
53881974	53881997	3	+	27260156	SKES1	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.017561096519166264	[834]	[780,943,749,817]	0	hSpCas9	negative selection	9043117
53877654	53877677	3	-	27260156	SKES1	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	0.0787954378292241	[610]	[693,825,532,555]	1	hSpCas9	negative selection	9043118
53877648	53877671	3	+	27260156	SKES1	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.3590331816210859	[1353]	[1197,1287,911,874]	-7	hSpCas9	negative selection	9107399
53878408	53878431	3	-	27260156	SKES1	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.06355060181000677	[375]	[467,485,214,415]	1	hSpCas9	negative selection	9107400
53878352	53878375	3	+	27260156	SKES1	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	0.04588149322946444	[173]	[181,233,142,164]	1	hSpCas9	negative selection	9107401
53881999	53882022	3	-	27260156	TOV112D	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.20285258088696123	[683]	[768,1330,558,629]	4	hSpCas9	negative selection	9164367
53881974	53881997	3	+	27260156	TOV112D	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.16378110643200217	[834]	[786,878,1009,1039]	3	hSpCas9	negative selection	9164368
53877654	53877677	3	-	27260156	TOV112D	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	0.14867719557787556	[610]	[759,716,690,563]	3	hSpCas9	negative selection	9164369
53877648	53877671	3	+	27260156	TOV112D	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.26984388747441024	[1353]	[1235,1688,870,856]	-5	hSpCas9	negative selection	9228650
53878408	53878431	3	-	27260156	TOV112D	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.18364695527577596	[375]	[541,485,347,359]	3	hSpCas9	negative selection	9228651
53878352	53878375	3	+	27260156	TOV112D	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.5555389882585897	[173]	[244,118,43,77]	-8	hSpCas9	negative selection	9228652
53881999	53882022	3	-	27260156	TC71	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.12586383815233704	[683]	[765,873,812,743]	3	hSpCas9	negative selection	9285618
53881974	53881997	3	+	27260156	TC71	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	-0.17447878716356413	[834]	[643,853,819,860]	-4	hSpCas9	negative selection	9285619
53877654	53877677	3	-	27260156	TC71	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	0.14778507173794414	[610]	[827,762,553,762]	4	hSpCas9	negative selection	9285620
53877648	53877671	3	+	27260156	TC71	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.10311985652657607	[1353]	[1354,1241,1150,1683]	-3	hSpCas9	negative selection	9349901
53878408	53878431	3	-	27260156	TC71	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.22150533017419832	[375]	[456,446,552,416]	5	hSpCas9	negative selection	9349902
53878352	53878375	3	+	27260156	TC71	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.23830967646167855	[173]	[85,197,160,190]	-6	hSpCas9	negative selection	9349903
53881999	53882022	3	-	27260156	TC32	viability	GCGGCCCATCGTGCCCGCGCTGG	ACTR8	ENSG00000113812	0.14460283625432901	[683]	[780,467,820,838]	2	hSpCas9	negative selection	9406869
53881974	53881997	3	+	27260156	TC32	viability	CGCACCTCTTGCAGCGACTCCGG	ACTR8	ENSG00000113812	0.11075872876267279	[834]	[691,769,1030,928]	2	hSpCas9	negative selection	9406870
53877654	53877677	3	-	27260156	TC32	viability	CATCACCCTGAGTATTTAGTAGG	ACTR8	ENSG00000113812	-0.15030603823900993	[610]	[354,434,726,615]	-3	hSpCas9	negative selection	9406871
53877648	53877671	3	+	27260156	TC32	viability	TCTTCTCCTACTAAATACTCAGG	ACTR8	ENSG00000113812	-0.4116905312533601	[1353]	[980,725,1305,895]	-6	hSpCas9	negative selection	9471152
53878408	53878431	3	-	27260156	TC32	viability	AAATGGTGGATCAAGCAATATGG	ACTR8	ENSG00000113812	0.14885977966119798	[375]	[367,405,326,427]	2	hSpCas9	negative selection	9471153
53878352	53878375	3	+	27260156	TC32	viability	CGAACCTGTTCAGGGGACACAGG	ACTR8	ENSG00000113812	-0.43405161651709134	[173]	[92,47,200,184]	-7	hSpCas9	negative selection	9471154
53871331	53871354	3	-	27869803	HPAFII	viability after 27 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.9622366278738734	[314]	[84,84,NaN]	-6	hSpCas9	negative selection	9585813
53873054	53873077	3	+	27869803	HPAFII	viability after 27 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.0740948255194027	[234]	[214,35,NaN]	0	hSpCas9	negative selection	9585814
53874299	53874322	3	-	27869803	HPAFII	viability after 27 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.11466600697619858	[259]	[189,112,NaN]	0	hSpCas9	negative selection	9585815
53877366	53877389	3	-	27869803	HPAFII	viability after 27 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	1.4736032658305143	[98]	[227,74,NaN]	9	hSpCas9	negative selection	9585816
53879984	53880007	3	-	27869803	HPAFII	viability after 27 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.2742349463740139	[577]	[301,208,NaN]	-2	hSpCas9	negative selection	9585817
53882074	53882097	3	+	27869803	HPAFII	viability after 27 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	0.6891879422227277	[418]	[466,261,NaN]	5	hSpCas9	negative selection	9585818
53871331	53871354	3	-	27869803	HPAFII	viability after 15 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.9088673407178758	[314]	[257,131,NaN]	-7	hSpCas9	negative selection	9668262
53873054	53873077	3	+	27869803	HPAFII	viability after 15 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.30386128693448383	[234]	[330,125,NaN]	-3	hSpCas9	negative selection	9668263
53874299	53874322	3	-	27869803	HPAFII	viability after 15 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.4015147812516307	[259]	[513,278,NaN]	4	hSpCas9	negative selection	9668264
53877366	53877389	3	-	27869803	HPAFII	viability after 15 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	0.9922069789110546	[98]	[387,101,NaN]	9	hSpCas9	negative selection	9668265
53879984	53880007	3	-	27869803	HPAFII	viability after 15 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.5865401504028676	[577]	[692,239,NaN]	-6	hSpCas9	negative selection	9668266
53882074	53882097	3	+	27869803	HPAFII	viability after 15 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	0.43271072871017735	[418]	[777,501,NaN]	5	hSpCas9	negative selection	9668267
53871331	53871354	3	-	27869803	ASPC1	viability after 36 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.7043205869328379	[606]	[734,250,142]	7	hSpCas9	negative selection	9750711
53873054	53873077	3	+	27869803	ASPC1	viability after 36 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.14505675722963063	[590]	[374,142,86]	-1	hSpCas9	negative selection	9750712
53874299	53874322	3	-	27869803	ASPC1	viability after 36 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	-0.2997061088964046	[562]	[359,66,90]	-3	hSpCas9	negative selection	9750713
53877366	53877389	3	-	27869803	ASPC1	viability after 36 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-0.7648072166428774	[333]	[180,11,33]	-6	hSpCas9	negative selection	9750714
53879984	53880007	3	-	27869803	ASPC1	viability after 36 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	0.257949229558351	[1144]	[562,413,463]	2	hSpCas9	negative selection	9750715
53882074	53882097	3	+	27869803	ASPC1	viability after 36 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.354828022944055	[1145]	[483,233,251]	-4	hSpCas9	negative selection	9750716
53871331	53871354	3	-	27869803	PATU8988S	viability after 35 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.9385231118821564	[570]	[57,61,NaN]	-9	hSpCas9	negative selection	9833160
53873054	53873077	3	+	27869803	PATU8988S	viability after 35 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-1.3935654618287532	[521]	[88,70,NaN]	-8	hSpCas9	negative selection	9833161
53874299	53874322	3	-	27869803	PATU8988S	viability after 35 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.2827049255329838	[441]	[238,193,NaN]	3	hSpCas9	negative selection	9833162
53877366	53877389	3	-	27869803	PATU8988S	viability after 35 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-1.9303153717602375	[297]	[26,35,NaN]	-9	hSpCas9	negative selection	9833163
53879984	53880007	3	-	27869803	PATU8988S	viability after 35 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.9038943405039934	[968]	[240,175,NaN]	-7	hSpCas9	negative selection	9833164
53882074	53882097	3	+	27869803	PATU8988S	viability after 35 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	-0.21246949349896227	[1061]	[433,303,NaN]	-2	hSpCas9	negative selection	9833165
53871331	53871354	3	-	27869803	PATU8988S	viability after 31 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.4878829217383791	[570]	[131,200,NaN]	-5	hSpCas9	negative selection	9915609
53873054	53873077	3	+	27869803	PATU8988S	viability after 31 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	-0.7679421736483463	[521]	[90,161,NaN]	-7	hSpCas9	negative selection	9915610
53874299	53874322	3	-	27869803	PATU8988S	viability after 31 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	0.5317758280649612	[441]	[245,265,NaN]	6	hSpCas9	negative selection	9915611
53877366	53877389	3	-	27869803	PATU8988S	viability after 31 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	-0.7907822168869438	[297]	[91,38,NaN]	-7	hSpCas9	negative selection	9915612
53879984	53880007	3	-	27869803	PATU8988S	viability after 31 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.333614160426511	[968]	[365,230,NaN]	-4	hSpCas9	negative selection	9915613
53882074	53882097	3	+	27869803	PATU8988S	viability after 31 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	0.28586164358624	[1061]	[433,620,NaN]	3	hSpCas9	negative selection	9915614
53871331	53871354	3	-	27869803	HPAFII	viability after 35 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-2.4711832124334276	[314]	[16,41,NaN]	-8	hSpCas9	negative selection	9998058
53873054	53873077	3	+	27869803	HPAFII	viability after 35 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	0.645680496626324	[234]	[314,40,NaN]	4	hSpCas9	negative selection	9998059
53874299	53874322	3	-	27869803	HPAFII	viability after 35 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	-0.35627220520471176	[259]	[99,105,NaN]	-2	hSpCas9	negative selection	9998060
53877366	53877389	3	-	27869803	HPAFII	viability after 35 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	1.848571163729007	[98]	[235,117,NaN]	9	hSpCas9	negative selection	9998061
53879984	53880007	3	-	27869803	HPAFII	viability after 35 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.2699501607612451	[577]	[300,176,NaN]	-2	hSpCas9	negative selection	9998062
53882074	53882097	3	+	27869803	HPAFII	viability after 35 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	0.6028009834961782	[418]	[236,417,NaN]	4	hSpCas9	negative selection	9998063
53871331	53871354	3	-	27869803	HPAFII	viability after 31 days	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.3026544007077188	[314]	[52,91,NaN]	-7	hSpCas9	negative selection	10080507
53873054	53873077	3	+	27869803	HPAFII	viability after 31 days	CGAAACTGGTAAAGCAGGGCAGG	ACTR8	ENSG00000113812	0.7356354225331413	[234]	[355,70,NaN]	5	hSpCas9	negative selection	10080508
53874299	53874322	3	-	27869803	HPAFII	viability after 31 days	TACTGGCTAATGCAGCGAGCTGG	ACTR8	ENSG00000113812	-0.27833247012906925	[259]	[104,136,NaN]	-2	hSpCas9	negative selection	10080509
53877366	53877389	3	-	27869803	HPAFII	viability after 31 days	GGCCTTGTATGTTAATCCACTGG	ACTR8	ENSG00000113812	1.4264300029018016	[98]	[167,128,NaN]	9	hSpCas9	negative selection	10080510
53879984	53880007	3	-	27869803	HPAFII	viability after 31 days	CCCGAAGACACAAACAACAAGGG	ACTR8	ENSG00000113812	-0.4441411655204264	[577]	[247,227,NaN]	-3	hSpCas9	negative selection	10080511
53882074	53882097	3	+	27869803	HPAFII	viability after 31 days	CCGTATCACCCTTCTCAGCCTGG	ACTR8	ENSG00000113812	0.41600356993154997	[418]	[307,319,NaN]	3	hSpCas9	negative selection	10080512
53870098	53870121	3	-	28162770	P31FUJ	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-3.651470954140091	[662]	[61]	-9	hSpCas9	negative selection	10106564
53871401	53871424	3	+	28162770	P31FUJ	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-0.6741738515066849	[257]	[189]	-5	hSpCas9	negative selection	10106565
53882052	53882075	3	-	28162770	P31FUJ	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-2.510786951714144	[96]	[19]	-8	hSpCas9	negative selection	10106566
53882038	53882061	3	-	28162770	P31FUJ	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.9876897065778474	[134]	[19]	-9	hSpCas9	negative selection	10106567
53879947	53879970	3	-	28162770	P31FUJ	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.6478397036932222	[135]	[101]	-5	hSpCas9	negative selection	10106568
53871331	53871354	3	-	28162770	P31FUJ	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.1063136754046239	[250]	[136]	-6	hSpCas9	negative selection	10106569
53871271	53871294	3	-	28162770	P31FUJ	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-1.178125111794064	[232]	[120]	-7	hSpCas9	negative selection	10106570
53882062	53882085	3	-	28162770	P31FUJ	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	0.7165717225156532	[28]	[55]	7	hSpCas9	negative selection	10106571
53882028	53882051	3	-	28162770	P31FUJ	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-2.2778119393319445	[292]	[70]	-8	hSpCas9	negative selection	10106572
53875973	53875996	3	-	28162770	P31FUJ	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-2.222748539750456	[142]	[35]	-8	hSpCas9	negative selection	10106573
53870098	53870121	3	-	28162770	TF1	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10275930
53871401	53871424	3	+	28162770	TF1	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10275931
53882052	53882075	3	-	28162770	TF1	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10275932
53882038	53882061	3	-	28162770	TF1	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10275933
53879947	53879970	3	-	28162770	TF1	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10275934
53871331	53871354	3	-	28162770	TF1	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10275935
53871271	53871294	3	-	28162770	TF1	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10275936
53882062	53882085	3	-	28162770	TF1	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10275937
53882028	53882051	3	-	28162770	TF1	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10275938
53875973	53875996	3	-	28162770	TF1	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	NaN	[NaN]	[27]	1	hSpCas9	negative selection	10275939
53870098	53870121	3	-	28162770	SKM1	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-1.3905697604924931	[174]	[117]	-7	hSpCas9	negative selection	10445296
53871401	53871424	3	+	28162770	SKM1	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-0.384937892413163	[64]	[87]	-3	hSpCas9	negative selection	10445297
53882052	53882075	3	-	28162770	SKM1	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-1.7480011165782288	[18]	[9]	-8	hSpCas9	negative selection	10445298
53882038	53882061	3	-	28162770	SKM1	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-4.484966710744435	[37]	[2]	-9	hSpCas9	negative selection	10445299
53879947	53879970	3	-	28162770	SKM1	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.75787136060229	[43]	[45]	-5	hSpCas9	negative selection	10445300
53871331	53871354	3	-	28162770	SKM1	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.24556158579062898	[72]	[152]	2	hSpCas9	negative selection	10445301
53871271	53871294	3	-	28162770	SKM1	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	0.2654611432283339	[47]	[101]	2	hSpCas9	negative selection	10445302
53882062	53882085	3	-	28162770	SKM1	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-1.5589672921882118	[4]	[2]	-8	hSpCas9	negative selection	10445303
53882028	53882051	3	-	28162770	SKM1	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-1.8220016980220057	[77]	[38]	-8	hSpCas9	negative selection	10445304
53875973	53875996	3	-	28162770	SKM1	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-0.9988794601060849	[25]	[22]	-6	hSpCas9	negative selection	10445305
53870098	53870121	3	-	28162770	SKM1	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-1.3905697604924931	[174]	[117]	-7	hSpCas9	negative selection	10614662
53871401	53871424	3	+	28162770	SKM1	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-0.384937892413163	[64]	[87]	-3	hSpCas9	negative selection	10614663
53882052	53882075	3	-	28162770	SKM1	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-1.7480011165782288	[18]	[9]	-8	hSpCas9	negative selection	10614664
53882038	53882061	3	-	28162770	SKM1	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-4.484966710744435	[37]	[2]	-9	hSpCas9	negative selection	10614665
53879947	53879970	3	-	28162770	SKM1	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.75787136060229	[43]	[45]	-5	hSpCas9	negative selection	10614666
53871331	53871354	3	-	28162770	SKM1	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.24556158579062898	[72]	[152]	2	hSpCas9	negative selection	10614667
53871271	53871294	3	-	28162770	SKM1	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	0.2654611432283339	[47]	[101]	2	hSpCas9	negative selection	10614668
53882062	53882085	3	-	28162770	SKM1	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-1.5589672921882118	[4]	[2]	-8	hSpCas9	negative selection	10614669
53882028	53882051	3	-	28162770	SKM1	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-1.8220016980220057	[77]	[38]	-8	hSpCas9	negative selection	10614670
53875973	53875996	3	-	28162770	SKM1	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-0.9988794601060849	[25]	[22]	-6	hSpCas9	negative selection	10614671
53870098	53870121	3	-	28162770	PL21	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-1.1673168202554138	[675]	[130]	-7	hSpCas9	negative selection	10784028
53871401	53871424	3	+	28162770	PL21	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-1.2428038813594082	[260]	[47]	-7	hSpCas9	negative selection	10784029
53882052	53882075	3	-	28162770	PL21	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-3.565395131873657	[135]	[4]	-9	hSpCas9	negative selection	10784030
53882038	53882061	3	-	28162770	PL21	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-0.42604554895834884	[141]	[45]	-3	hSpCas9	negative selection	10784031
53879947	53879970	3	-	28162770	PL21	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.851699317030298	[169]	[40]	-5	hSpCas9	negative selection	10784032
53871331	53871354	3	-	28162770	PL21	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.756791663618794	[263]	[33]	-8	hSpCas9	negative selection	10784033
53871271	53871294	3	-	28162770	PL21	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-0.5028786477535485	[139]	[42]	-4	hSpCas9	negative selection	10784034
53882062	53882085	3	-	28162770	PL21	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-1.3848228862318366	[23]	[3]	-7	hSpCas9	negative selection	10784035
53882028	53882051	3	-	28162770	PL21	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-2.3556765405723197	[293]	[24]	-8	hSpCas9	negative selection	10784036
53875973	53875996	3	-	28162770	PL21	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-0.2523725902081866	[103]	[37]	-2	hSpCas9	negative selection	10784037
53870098	53870121	3	-	28162770	P31FUJ	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-3.651470954140091	[662]	[61]	-9	hSpCas9	negative selection	10953394
53871401	53871424	3	+	28162770	P31FUJ	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-0.6741738515066849	[257]	[189]	-5	hSpCas9	negative selection	10953395
53882052	53882075	3	-	28162770	P31FUJ	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-2.510786951714144	[96]	[19]	-8	hSpCas9	negative selection	10953396
53882038	53882061	3	-	28162770	P31FUJ	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.9876897065778474	[134]	[19]	-9	hSpCas9	negative selection	10953397
53879947	53879970	3	-	28162770	P31FUJ	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.6478397036932222	[135]	[101]	-5	hSpCas9	negative selection	10953398
53871331	53871354	3	-	28162770	P31FUJ	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.1063136754046239	[250]	[136]	-6	hSpCas9	negative selection	10953399
53871271	53871294	3	-	28162770	P31FUJ	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-1.178125111794064	[232]	[120]	-7	hSpCas9	negative selection	10953400
53882062	53882085	3	-	28162770	P31FUJ	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	0.7165717225156532	[28]	[55]	7	hSpCas9	negative selection	10953401
53882028	53882051	3	-	28162770	P31FUJ	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-2.2778119393319445	[292]	[70]	-8	hSpCas9	negative selection	10953402
53875973	53875996	3	-	28162770	P31FUJ	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-2.222748539750456	[142]	[35]	-8	hSpCas9	negative selection	10953403
53870098	53870121	3	-	28162770	OCIAML5	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-1.2121778596392474	[334]	[260]	-6	hSpCas9	negative selection	11122760
53871401	53871424	3	+	28162770	OCIAML5	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-0.832701245997066	[221]	[224]	-5	hSpCas9	negative selection	11122761
53882052	53882075	3	-	28162770	OCIAML5	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-6.495922760638722	[49]	[0]	-9	hSpCas9	negative selection	11122762
53882038	53882061	3	-	28162770	OCIAML5	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-1.2057035254786976	[91]	[71]	-6	hSpCas9	negative selection	11122763
53879947	53879970	3	-	28162770	OCIAML5	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-1.2105205417764733	[99]	[77]	-6	hSpCas9	negative selection	11122764
53871331	53871354	3	-	28162770	OCIAML5	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.9413339089610843	[149]	[140]	-5	hSpCas9	negative selection	11122765
53871271	53871294	3	-	28162770	OCIAML5	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-0.029709485467146246	[81]	[144]	0	hSpCas9	negative selection	11122766
53882062	53882085	3	-	28162770	OCIAML5	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-3.7780659894202198	[37]	[4]	-9	hSpCas9	negative selection	11122767
53882028	53882051	3	-	28162770	OCIAML5	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-2.93006908286527	[151]	[35]	-8	hSpCas9	negative selection	11122768
53875973	53875996	3	-	28162770	OCIAML5	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-1.3215518541652174	[71]	[51]	-6	hSpCas9	negative selection	11122769
53870098	53870121	3	-	28162770	EOL1	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-1.8887515142363265	[1215]	[172]	-8	hSpCas9	negative selection	11292126
53871401	53871424	3	+	28162770	EOL1	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-0.39984436326830886	[292]	[116]	-3	hSpCas9	negative selection	11292127
53882052	53882075	3	-	28162770	EOL1	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-6.518395724278194	[173]	[0]	-9	hSpCas9	negative selection	11292128
53882038	53882061	3	-	28162770	EOL1	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.216464537956539	[246]	[27]	-8	hSpCas9	negative selection	11292129
53879947	53879970	3	-	28162770	EOL1	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.6252253006883216	[242]	[82]	-4	hSpCas9	negative selection	11292130
53871331	53871354	3	-	28162770	EOL1	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.1695744057940155	[379]	[177]	-1	hSpCas9	negative selection	11292131
53871271	53871294	3	-	28162770	EOL1	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-0.7325645149064568	[204]	[64]	-5	hSpCas9	negative selection	11292132
53882062	53882085	3	-	28162770	EOL1	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	2.8278717521588606	[26]	[100]	9	hSpCas9	negative selection	11292133
53882028	53882051	3	-	28162770	EOL1	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-0.5320906321750822	[386]	[140]	-4	hSpCas9	negative selection	11292134
53875973	53875996	3	-	28162770	EOL1	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-1.2517750010699285	[112]	[24]	-7	hSpCas9	negative selection	11292135
53870098	53870121	3	-	28162770	MOLM13	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-3.0634920789717333	[924]	[79]	-8	hSpCas9	negative selection	11461492
53871401	53871424	3	+	28162770	MOLM13	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-1.1764516662555091	[371]	[118]	-6	hSpCas9	negative selection	11461493
53882052	53882075	3	-	28162770	MOLM13	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-6.7415639840843715	[147]	[0]	-9	hSpCas9	negative selection	11461494
53882038	53882061	3	-	28162770	MOLM13	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.8094485623187126	[222]	[22]	-8	hSpCas9	negative selection	11461495
53879947	53879970	3	-	28162770	MOLM13	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-2.012103559575035	[211]	[37]	-7	hSpCas9	negative selection	11461496
53871331	53871354	3	-	28162770	MOLM13	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.2730781431791236	[360]	[107]	-6	hSpCas9	negative selection	11461497
53871271	53871294	3	-	28162770	MOLM13	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-1.8391654368612533	[192]	[38]	-7	hSpCas9	negative selection	11461498
53882062	53882085	3	-	28162770	MOLM13	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-4.7020356198977336	[71]	[1]	-9	hSpCas9	negative selection	11461499
53882028	53882051	3	-	28162770	MOLM13	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-5.07299205071246	[418]	[8]	-9	hSpCas9	negative selection	11461500
53875973	53875996	3	-	28162770	MOLM13	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-6.915814910929474	[166]	[0]	-9	hSpCas9	negative selection	11461501
53870098	53870121	3	-	28162770	HEL	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-2.7041356200172366	[874]	[85]	-8	hSpCas9	negative selection	11630858
53871401	53871424	3	+	28162770	HEL	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-1.1419931810965767	[347]	[100]	-6	hSpCas9	negative selection	11630859
53882052	53882075	3	-	28162770	HEL	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-6.732300599346567	[165]	[0]	-9	hSpCas9	negative selection	11630860
53882038	53882061	3	-	28162770	HEL	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-4.419037365586332	[166]	[4]	-9	hSpCas9	negative selection	11630861
53879947	53879970	3	-	28162770	HEL	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-0.4205871033684724	[162]	[77]	-3	hSpCas9	negative selection	11630862
53871331	53871354	3	-	28162770	HEL	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.5611335013652932	[257]	[111]	-4	hSpCas9	negative selection	11630863
53871271	53871294	3	-	28162770	HEL	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-1.3191931271661232	[186]	[47]	-6	hSpCas9	negative selection	11630864
53882062	53882085	3	-	28162770	HEL	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-3.4865441849446093	[34]	[1]	-9	hSpCas9	negative selection	11630865
53882028	53882051	3	-	28162770	HEL	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-2.2683274395793545	[345]	[45]	-8	hSpCas9	negative selection	11630866
53875973	53875996	3	-	28162770	HEL	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-1.9852923906126851	[135]	[21]	-8	hSpCas9	negative selection	11630867
53870098	53870121	3	-	28162770	MV411	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-3.0184565091902593	[605]	[62]	-9	hSpCas9	negative selection	11800224
53871401	53871424	3	+	28162770	MV411	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-1.300999073913267	[233]	[79]	-7	hSpCas9	negative selection	11800225
53882052	53882075	3	-	28162770	MV411	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-6.546978315567331	[110]	[0]	-9	hSpCas9	negative selection	11800226
53882038	53882061	3	-	28162770	MV411	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-1.8680396666371606	[194]	[44]	-8	hSpCas9	negative selection	11800227
53879947	53879970	3	-	28162770	MV411	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-1.45927022229075	[172]	[52]	-7	hSpCas9	negative selection	11800228
53871331	53871354	3	-	28162770	MV411	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-1.105443472433499	[211]	[82]	-6	hSpCas9	negative selection	11800229
53871271	53871294	3	-	28162770	MV411	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	0.02504512944632742	[97]	[83]	0	hSpCas9	negative selection	11800230
53882062	53882085	3	-	28162770	MV411	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-2.296882965441035	[34]	[5]	-8	hSpCas9	negative selection	11800231
53882028	53882051	3	-	28162770	MV411	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-3.222448425491688	[276]	[24]	-9	hSpCas9	negative selection	11800232
53875973	53875996	3	-	28162770	MV411	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-2.074490544104587	[114]	[22]	-8	hSpCas9	negative selection	11800233
53870098	53870121	3	-	28162770	MONOMAC1	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-2.2330161441651204	[405]	[98]	-9	hSpCas9	negative selection	11969590
53871401	53871424	3	+	28162770	MONOMAC1	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-0.38146141819698104	[149]	[131]	-3	hSpCas9	negative selection	11969591
53882052	53882075	3	-	28162770	MONOMAC1	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-1.4683388688769479	[69]	[28]	-8	hSpCas9	negative selection	11969592
53882038	53882061	3	-	28162770	MONOMAC1	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-3.646344248423144	[141]	[12]	-9	hSpCas9	negative selection	11969593
53879947	53879970	3	-	28162770	MONOMAC1	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-1.131448505431977	[85]	[44]	-7	hSpCas9	negative selection	11969594
53871331	53871354	3	-	28162770	MONOMAC1	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.8447351031286724	[140]	[89]	-6	hSpCas9	negative selection	11969595
53871271	53871294	3	-	28162770	MONOMAC1	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-0.7055012103066666	[100]	[70]	-5	hSpCas9	negative selection	11969596
53882062	53882085	3	-	28162770	MONOMAC1	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	0.09246977013543134	[8]	[10]	0	hSpCas9	negative selection	11969597
53882028	53882051	3	-	28162770	MONOMAC1	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-1.8719414730935084	[181]	[56]	-8	hSpCas9	negative selection	11969598
53875973	53875996	3	-	28162770	MONOMAC1	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-1.1750105407295548	[64]	[32]	-7	hSpCas9	negative selection	11969599
53870098	53870121	3	-	28162770	OCIAML2	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-3.042881274213763	[112]	[75]	-9	hSpCas9	negative selection	12138956
53871401	53871424	3	+	28162770	OCIAML2	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	0.12840786069071777	[33]	[205]	1	hSpCas9	negative selection	12138957
53882052	53882075	3	-	28162770	OCIAML2	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-6.930061443879459	[21]	[0]	-9	hSpCas9	negative selection	12138958
53882038	53882061	3	-	28162770	OCIAML2	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-4.663274903184558	[31]	[6]	-9	hSpCas9	negative selection	12138959
53879947	53879970	3	-	28162770	OCIAML2	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-1.0213224238785716	[25]	[70]	-6	hSpCas9	negative selection	12138960
53871331	53871354	3	-	28162770	OCIAML2	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	-0.6055594053282698	[41]	[152]	-4	hSpCas9	negative selection	12138961
53871271	53871294	3	-	28162770	OCIAML2	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-1.0662395701628258	[33]	[89]	-6	hSpCas9	negative selection	12138962
53882062	53882085	3	-	28162770	OCIAML2	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-5.277984747299765	[6]	[0]	-9	hSpCas9	negative selection	12138963
53882028	53882051	3	-	28162770	OCIAML2	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-4.816404662083892	[60]	[11]	-9	hSpCas9	negative selection	12138964
53875973	53875996	3	-	28162770	OCIAML2	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-1.994191781299174	[22]	[31]	-8	hSpCas9	negative selection	12138965
53870098	53870121	3	-	28162770	OCIAML3	viability	GTACAGCTCCATCCTAGTGGTGG	ACTR8	ENSG00000113812	-2.6777759980167612	[194]	[91]	-9	hSpCas9	negative selection	12308322
53871401	53871424	3	+	28162770	OCIAML3	viability	GAGTCTTTCTGGAAGATCAGAGG	ACTR8	ENSG00000113812	-1.2552057268724046	[67]	[85]	-7	hSpCas9	negative selection	12308323
53882052	53882075	3	-	28162770	OCIAML3	viability	GAGAACGGAAAGGAGAAGGGCGG	ACTR8	ENSG00000113812	-3.972519263577893	[25]	[4]	-9	hSpCas9	negative selection	12308324
53882038	53882061	3	-	28162770	OCIAML3	viability	GAAGGGCGGCGAGAAGGAGAAGG	ACTR8	ENSG00000113812	-2.996106083895509	[36]	[13]	-9	hSpCas9	negative selection	12308325
53879947	53879970	3	-	28162770	OCIAML3	viability	GGACAGTTGGCTCCTAAGGGAGG	ACTR8	ENSG00000113812	-1.2595886012536042	[45]	[57]	-7	hSpCas9	negative selection	12308326
53871331	53871354	3	-	28162770	OCIAML3	viability	GGCCGGCAACGATTCCGAGGAGG	ACTR8	ENSG00000113812	0.5214695770957729	[50]	[220]	5	hSpCas9	negative selection	12308327
53871271	53871294	3	-	28162770	OCIAML3	viability	GCTGTTTGAAGGAAAAGCCCTGG	ACTR8	ENSG00000113812	-0.5115454801321901	[33]	[71]	-4	hSpCas9	negative selection	12308328
53882062	53882085	3	-	28162770	OCIAML3	viability	GGGTGATACGGAGAACGGAAAGG	ACTR8	ENSG00000113812	-1.5940076403241634	[4]	[4]	-8	hSpCas9	negative selection	12308329
53882028	53882051	3	-	28162770	OCIAML3	viability	GAGAAGGAGAAGGAGCAGCGCGG	ACTR8	ENSG00000113812	-3.4519886354517353	[57]	[15]	-9	hSpCas9	negative selection	12308330
53875973	53875996	3	-	28162770	OCIAML3	viability	GACAAGTGTATGCTGTGTGGAGG	ACTR8	ENSG00000113812	-1.5615861626317857	[43]	[44]	-8	hSpCas9	negative selection	12308331