Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:84517
• Symbol:ACTRT3
• Description:actin related protein T3

DataSource: http://genomecrispr.dkfz.de/#!/results/ACTRT3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
169769496	169769519	3	-	26472758	Jiyoye	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.24490395260699627	[281]	[251]	1	hSpCas9	negative selection	2283
169767788	169767811	3	+	26472758	Jiyoye	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	1.6702097873396673	[19]	[47]	8	hSpCas9	negative selection	2284
169769361	169769384	3	-	26472758	Jiyoye	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.2551722880608238	[29]	[26]	2	hSpCas9	negative selection	2285
169769338	169769361	3	-	26472758	Jiyoye	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.8428028715024742	[87]	[36]	-5	hSpCas9	negative selection	2286
169769478	169769501	3	-	26472758	Jiyoye	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	-0.5362410901277592	[49]	[25]	-4	hSpCas9	negative selection	2287
169769463	169769486	3	-	26472758	Jiyoye	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.8966053666712297	[157]	[63]	-6	hSpCas9	negative selection	2288
169769420	169769443	3	+	26472758	Jiyoye	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.21873029209276318	[48]	[42]	1	hSpCas9	negative selection	2289
169769403	169769426	3	-	26472758	Jiyoye	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	0.4506770201424599	[97]	[100]	3	hSpCas9	negative selection	2290
169767964	169767987	3	-	26472758	Jiyoye	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	-0.09142683441210173	[153]	[108]	0	hSpCas9	negative selection	2291
169767878	169767901	3	-	26472758	Jiyoye	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	-1.040283595465348	[89]	[32]	-6	hSpCas9	negative selection	2292
169769496	169769519	3	-	26472758	KBM7	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.08988592949903418	[1113,571]	[248,553]	0	hSpCas9	negative selection	193401
169767788	169767811	3	+	26472758	KBM7	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	0.3783317036049665	[204,154]	[80,133]	4	hSpCas9	negative selection	193402
169769361	169769384	3	-	26472758	KBM7	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.7024440961286514	[237,122]	[62,197]	7	hSpCas9	negative selection	193403
169769338	169769361	3	-	26472758	KBM7	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.4130851717179124	[281,306]	[212,161]	4	hSpCas9	negative selection	193404
169769478	169769501	3	-	26472758	KBM7	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	-0.47524903943795216	[286,200]	[91,71]	-4	hSpCas9	negative selection	193405
169769463	169769486	3	-	26472758	KBM7	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.06928840418113791	[392,288]	[167,164]	0	hSpCas9	negative selection	193406
169769420	169769443	3	+	26472758	KBM7	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.11838999338876177	[319,230]	[129,146]	1	hSpCas9	negative selection	193407
169769403	169769426	3	-	26472758	KBM7	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	0.8608884084608773	[400,562]	[407,431]	8	hSpCas9	negative selection	193408
169767964	169767987	3	-	26472758	KBM7	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.5987674778249407	[736,633]	[434,532]	6	hSpCas9	negative selection	193409
169767878	169767901	3	-	26472758	KBM7	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	-1.2439183537833867	[368,389]	[67,82]	-7	hSpCas9	negative selection	193410
169769496	169769519	3	-	26472758	Raji	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.9298453498214121	[379]	[167]	8	hSpCas9	negative selection	384519
169767788	169767811	3	+	26472758	Raji	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	0.3911765013741907	[91]	[27]	4	hSpCas9	negative selection	384520
169769361	169769384	3	-	26472758	Raji	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.7636300239063225	[138]	[18]	-5	hSpCas9	negative selection	384521
169769338	169769361	3	-	26472758	Raji	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.3626405906156739	[123]	[36]	3	hSpCas9	negative selection	384522
169769478	169769501	3	-	26472758	Raji	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	-0.23744496162384165	[126]	[24]	-2	hSpCas9	negative selection	384523
169769463	169769486	3	-	26472758	Raji	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.4300505952649709	[208]	[35]	-4	hSpCas9	negative selection	384524
169769420	169769443	3	+	26472758	Raji	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.6384791641160199	[190]	[68]	6	hSpCas9	negative selection	384525
169769403	169769426	3	-	26472758	Raji	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	-0.008093682046336426	[285]	[65]	0	hSpCas9	negative selection	384526
169767964	169767987	3	-	26472758	Raji	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.39651213735853774	[346]	[105]	4	hSpCas9	negative selection	384527
169767878	169767901	3	-	26472758	Raji	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	0.38155849881259374	[128]	[38]	3	hSpCas9	negative selection	384528
169769496	169769519	3	-	26472758	K562	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.012816829669310192	[680]	[579]	0	hSpCas9	negative selection	575637
169767788	169767811	3	+	26472758	K562	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	0.8384263679906099	[158]	[239]	7	hSpCas9	negative selection	575638
169769361	169769384	3	-	26472758	K562	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.969311489532078	[143]	[237]	7	hSpCas9	negative selection	575639
169769338	169769361	3	-	26472758	K562	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.6303717344891059	[237]	[310]	5	hSpCas9	negative selection	575640
169769478	169769501	3	-	26472758	K562	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	1.7907783891638558	[100]	[294]	9	hSpCas9	negative selection	575641
169769463	169769486	3	-	26472758	K562	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.6316730704317527	[366]	[479]	5	hSpCas9	negative selection	575642
169769420	169769443	3	+	26472758	K562	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	1.1275374273708278	[256]	[473]	8	hSpCas9	negative selection	575643
169769403	169769426	3	-	26472758	K562	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	0.19781831480430767	[408]	[395]	1	hSpCas9	negative selection	575644
169767964	169767987	3	-	26472758	K562	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.8618795862612296	[555]	[852]	7	hSpCas9	negative selection	575645
169767878	169767901	3	-	26472758	K562	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	0.3709511335953785	[239]	[261]	3	hSpCas9	negative selection	575646
169767619	169767642	3	+	26627737	DLD1	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.22655072737614396	[527]	[128,96,187]	-2	hSpCas9	negative selection	820370
169767620	169767643	3	+	26627737	DLD1	viability	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.38326866459976106	[740]	[247,376,286]	4	hSpCas9	negative selection	820371
169767748	169767771	3	+	26627737	DLD1	viability	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.27243827907732315	[547]	[105,131,180]	-3	hSpCas9	negative selection	820372
169769341	169769364	3	-	26627737	DLD1	viability	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	0.29190726540123446	[974]	[252,498,372]	3	hSpCas9	negative selection	820373
169769364	169769387	3	+	26627737	DLD1	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	0.007156191402267975	[1113]	[327,233,464]	0	hSpCas9	negative selection	820374
169769463	169769486	3	-	26627737	DLD1	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.47382136477930786	[598]	[196,284,293]	5	hSpCas9	negative selection	820375
169767619	169767642	3	+	26627737	GBM cells	viability after 5 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.31427858046079604	[494]	[194,231]	-5	hSpCas9	negative selection	902685
169767620	169767643	3	+	26627737	GBM cells	viability after 5 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.18173678510255298	[514]	[244,241]	-3	hSpCas9	negative selection	902686
169767748	169767771	3	+	26627737	GBM cells	viability after 5 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	0.0025365059598428663	[281]	[181,120]	0	hSpCas9	negative selection	902687
169769341	169769364	3	-	26627737	GBM cells	viability after 5 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.37779546784518464	[423]	[198,150]	-5	hSpCas9	negative selection	902688
169769364	169769387	3	+	26627737	GBM cells	viability after 5 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.5909864288638642	[322]	[120,108]	-7	hSpCas9	negative selection	902689
169769463	169769486	3	-	26627737	GBM cells	viability after 5 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.40773352048514655	[401]	[269,301]	6	hSpCas9	negative selection	902690
169767619	169767642	3	+	26627737	GBM cells	viability after 13 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.33352602321138136	[494]	[216,209]	-4	hSpCas9	negative selection	985000
169767620	169767643	3	+	26627737	GBM cells	viability after 13 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.0404283381330135	[514]	[261,307]	0	hSpCas9	negative selection	985001
169767748	169767771	3	+	26627737	GBM cells	viability after 13 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	0.07918959248038979	[281]	[202,127]	1	hSpCas9	negative selection	985002
169769341	169769364	3	-	26627737	GBM cells	viability after 13 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.3435120045870229	[423]	[177,183]	-4	hSpCas9	negative selection	985003
169769364	169769387	3	+	26627737	GBM cells	viability after 13 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-1.1714253699584776	[322]	[111,49]	-8	hSpCas9	negative selection	985004
169769463	169769486	3	-	26627737	GBM cells	viability after 13 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.09003801293356573	[401]	[283,189]	1	hSpCas9	negative selection	985005
169767619	169767642	3	+	26627737	GBM cells	viability after 21 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.6895565307692382	[494]	[160,171]	-6	hSpCas9	negative selection	1067315
169767620	169767643	3	+	26627737	GBM cells	viability after 21 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.30645676621188866	[514]	[243,209]	-3	hSpCas9	negative selection	1067316
169767748	169767771	3	+	26627737	GBM cells	viability after 21 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	0.5626330447779673	[281]	[254,199]	6	hSpCas9	negative selection	1067317
169769341	169769364	3	-	26627737	GBM cells	viability after 21 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.5793401002650225	[423]	[161,146]	-5	hSpCas9	negative selection	1067318
169769364	169769387	3	+	26627737	GBM cells	viability after 21 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-1.4097917508693452	[322]	[64,66]	-8	hSpCas9	negative selection	1067319
169769463	169769486	3	-	26627737	GBM cells	viability after 21 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.38658468962436954	[401]	[296,274]	4	hSpCas9	negative selection	1067320
169767619	169767642	3	+	26627737	RPE1	viability after 9 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.25780704431731327	[765]	[246,337]	1	hSpCas9	negative selection	1149630
169767620	169767643	3	+	26627737	RPE1	viability after 9 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.02099796507525964	[1157]	[286,447]	0	hSpCas9	negative selection	1149631
169767748	169767771	3	+	26627737	RPE1	viability after 9 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.02610457427867019	[1165]	[292,442]	0	hSpCas9	negative selection	1149632
169769341	169769364	3	-	26627737	RPE1	viability after 9 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.5104766785625443	[2061]	[288,664]	-4	hSpCas9	negative selection	1149633
169769364	169769387	3	+	26627737	RPE1	viability after 9 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.8860179652926906	[2350]	[282,546]	-6	hSpCas9	negative selection	1149634
169769463	169769486	3	-	26627737	RPE1	viability after 9 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.6983803732610341	[1597]	[558,1137]	4	hSpCas9	negative selection	1149635
169767619	169767642	3	+	26627737	RPE1	viability after 12 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.6996020865438715	[765]	[171,505]	4	hSpCas9	negative selection	1231945
169767620	169767643	3	+	26627737	RPE1	viability after 12 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.03460145403116399	[1157]	[311,294]	0	hSpCas9	negative selection	1231946
169767748	169767771	3	+	26627737	RPE1	viability after 12 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.14250988235416945	[1165]	[225,344]	-1	hSpCas9	negative selection	1231947
169769341	169769364	3	-	26627737	RPE1	viability after 12 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.21233308639299553	[2061]	[449,507]	-1	hSpCas9	negative selection	1231948
169769364	169769387	3	+	26627737	RPE1	viability after 12 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	0.05699035459682422	[2350]	[523,797]	0	hSpCas9	negative selection	1231949
169769463	169769486	3	-	26627737	RPE1	viability after 12 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.6018392515453115	[1597]	[398,918]	4	hSpCas9	negative selection	1231950
169767619	169767642	3	+	26627737	RPE1	viability after 15 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.10828825353683799	[765]	[144,318]	0	hSpCas9	negative selection	1314260
169767620	169767643	3	+	26627737	RPE1	viability after 15 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.24537337534227976	[1157]	[200,348]	-1	hSpCas9	negative selection	1314261
169767748	169767771	3	+	26627737	RPE1	viability after 15 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.47121064360753356	[1165]	[269,206]	-3	hSpCas9	negative selection	1314262
169769341	169769364	3	-	26627737	RPE1	viability after 15 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.39054291577476596	[2061]	[418,469]	-2	hSpCas9	negative selection	1314263
169769364	169769387	3	+	26627737	RPE1	viability after 15 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.00887262188599136	[2350]	[268,1038]	0	hSpCas9	negative selection	1314264
169769463	169769486	3	-	26627737	RPE1	viability after 15 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.3853024815340229	[1597]	[425,748]	2	hSpCas9	negative selection	1314265
169767619	169767642	3	+	26627737	RPE1	viability after 18 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.6692887643369625	[765]	[262,398]	4	hSpCas9	negative selection	1396575
169767620	169767643	3	+	26627737	RPE1	viability after 18 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.24287232385823387	[1157]	[436,297]	1	hSpCas9	negative selection	1396576
169767748	169767771	3	+	26627737	RPE1	viability after 18 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.2770526970307727	[1165]	[337,175]	-2	hSpCas9	negative selection	1396577
169769341	169769364	3	-	26627737	RPE1	viability after 18 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.5067418278198726	[2061]	[395,386]	-3	hSpCas9	negative selection	1396578
169769364	169769387	3	+	26627737	RPE1	viability after 18 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	0.6245867031200276	[2350]	[502,1485]	4	hSpCas9	negative selection	1396579
169769463	169769486	3	-	26627737	RPE1	viability after 18 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.4711951284313336	[1597]	[344,867]	3	hSpCas9	negative selection	1396580
169767619	169767642	3	+	26627737	HeLa	viability after 8 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.14757722359183537	[459]	[233,228,205]	1	hSpCas9	negative selection	1478890
169767620	169767643	3	+	26627737	HeLa	viability after 8 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.14666474953607478	[731]	[498,260,158]	-1	hSpCas9	negative selection	1478891
169767748	169767771	3	+	26627737	HeLa	viability after 8 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.10565891216319784	[365]	[193,94,163]	-1	hSpCas9	negative selection	1478892
169769341	169769364	3	-	26627737	HeLa	viability after 8 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.28587849643818064	[1057]	[335,310,469]	-3	hSpCas9	negative selection	1478893
169769364	169769387	3	+	26627737	HeLa	viability after 8 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.05685831325660651	[909]	[188,517,391]	0	hSpCas9	negative selection	1478894
169769463	169769486	3	-	26627737	HeLa	viability after 8 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.09617598728977172	[588]	[319,222,287]	0	hSpCas9	negative selection	1478895
169767619	169767642	3	+	26627737	HeLa	viability after 12 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.022879117193097376	[459]	[224,186,168]	0	hSpCas9	negative selection	1561205
169767620	169767643	3	+	26627737	HeLa	viability after 12 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.12755466478141397	[731]	[334,195,309]	-1	hSpCas9	negative selection	1561206
169767748	169767771	3	+	26627737	HeLa	viability after 12 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	0.05562240310464492	[365]	[181,197,87]	0	hSpCas9	negative selection	1561207
169769341	169769364	3	-	26627737	HeLa	viability after 12 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.885703608194408	[1057]	[165,376,149]	-7	hSpCas9	negative selection	1561208
169769364	169769387	3	+	26627737	HeLa	viability after 12 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.29287338171313393	[909]	[512,192,232]	-3	hSpCas9	negative selection	1561209
169769463	169769486	3	-	26627737	HeLa	viability after 12 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.22857272929737626	[588]	[177,336,331]	2	hSpCas9	negative selection	1561210
169767619	169767642	3	+	26627737	HeLa	viability after 15 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.2410629873220745	[459]	[60,347,259]	2	hSpCas9	negative selection	1643520
169767620	169767643	3	+	26627737	HeLa	viability after 15 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.2863042982562082	[731]	[282,332,105]	-2	hSpCas9	negative selection	1643521
169767748	169767771	3	+	26627737	HeLa	viability after 15 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.029943801246504392	[365]	[174,145,113]	0	hSpCas9	negative selection	1643522
169769341	169769364	3	-	26627737	HeLa	viability after 15 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.7746392391582965	[1057]	[216,283,254]	-6	hSpCas9	negative selection	1643523
169769364	169769387	3	+	26627737	HeLa	viability after 15 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.3777524199341431	[909]	[181,397,275]	-3	hSpCas9	negative selection	1643524
169769463	169769486	3	-	26627737	HeLa	viability after 15 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.11332427382488697	[588]	[144,442,185]	1	hSpCas9	negative selection	1643525
169767619	169767642	3	+	26627737	HeLa	viability after 18 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.21859955961477603	[459]	[39,280,259]	1	hSpCas9	negative selection	1725835
169767620	169767643	3	+	26627737	HeLa	viability after 18 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.2558800790212068	[731]	[194,281,105]	-2	hSpCas9	negative selection	1725836
169767748	169767771	3	+	26627737	HeLa	viability after 18 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.02554291137023526	[365]	[114,124,113]	0	hSpCas9	negative selection	1725837
169769341	169769364	3	-	26627737	HeLa	viability after 18 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.7999814792311838	[1057]	[133,238,254]	-6	hSpCas9	negative selection	1725838
169769364	169769387	3	+	26627737	HeLa	viability after 18 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.3880890354190104	[909]	[116,330,275]	-3	hSpCas9	negative selection	1725839
169769463	169769486	3	-	26627737	HeLa	viability after 18 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.10258263687162461	[588]	[94,364,185]	0	hSpCas9	negative selection	1725840
169767619	169767642	3	+	26627737	HCT116	viability after 6 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.7148659834690325	[733]	[229,166]	4	hSpCas9	negative selection	1808150
169767620	169767643	3	+	26627737	HCT116	viability after 6 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.9490604162120133	[876]	[144,332]	5	hSpCas9	negative selection	1808151
169767748	169767771	3	+	26627737	HCT116	viability after 6 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-1.4405066872125114	[383]	[38,12]	-7	hSpCas9	negative selection	1808152
169769341	169769364	3	-	26627737	HCT116	viability after 6 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	1.1015928782878008	[726]	[310,208]	6	hSpCas9	negative selection	1808153
169769364	169769387	3	+	26627737	HCT116	viability after 6 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	1.3988601511778391	[933]	[615,260]	7	hSpCas9	negative selection	1808154
169769463	169769486	3	-	26627737	HCT116	viability after 6 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	2.0023527959388843	[974]	[898,456]	8	hSpCas9	negative selection	1808155
169767619	169767642	3	+	26627737	HCT116	viability after 8 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.7154608278370038	[265]	[216,296,207]	6	hSpCas9	negative selection	1890465
169767620	169767643	3	+	26627737	HCT116	viability after 8 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.5798172743989118	[541]	[176,218,202]	-6	hSpCas9	negative selection	1890466
169767748	169767771	3	+	26627737	HCT116	viability after 8 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.8366619764337087	[408]	[116,100,159]	-8	hSpCas9	negative selection	1890467
169769341	169769364	3	-	26627737	HCT116	viability after 8 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	0.6646573497563497	[516]	[429,440,482]	6	hSpCas9	negative selection	1890468
169769364	169769387	3	+	26627737	HCT116	viability after 8 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	0.9745014534016411	[251]	[280,206,329]	8	hSpCas9	negative selection	1890469
169769463	169769486	3	-	26627737	HCT116	viability after 8 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.18483411803590655	[546]	[350,335,340]	2	hSpCas9	negative selection	1890470
169767619	169767642	3	+	26627737	HCT116	viability after 9 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.0008589334098282886	[733]	[175,211]	0	hSpCas9	negative selection	1972780
169767620	169767643	3	+	26627737	HCT116	viability after 9 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.38802438121792604	[876]	[182,403]	3	hSpCas9	negative selection	1972781
169767748	169767771	3	+	26627737	HCT116	viability after 9 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	1.2444653591928416	[383]	[171,298]	7	hSpCas9	negative selection	1972782
169769341	169769364	3	-	26627737	HCT116	viability after 9 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	0.9509990824740178	[726]	[281,448]	6	hSpCas9	negative selection	1972783
169769364	169769387	3	+	26627737	HCT116	viability after 9 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.1975069766297864	[933]	[126,288]	-1	hSpCas9	negative selection	1972784
169769463	169769486	3	-	26627737	HCT116	viability after 9 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.31113756019879074	[974]	[239,185]	-2	hSpCas9	negative selection	1972785
169767619	169767642	3	+	26627737	HCT116	viability after 12 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.3945277276843571	[265]	[109,152,293]	4	hSpCas9	negative selection	2055095
169767620	169767643	3	+	26627737	HCT116	viability after 12 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.5171117553699729	[541]	[233,238,121]	-5	hSpCas9	negative selection	2055096
169767748	169767771	3	+	26627737	HCT116	viability after 12 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-1.466505799572309	[408]	[52,97,84]	-9	hSpCas9	negative selection	2055097
169769341	169769364	3	-	26627737	HCT116	viability after 12 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	0.07073225945193318	[516]	[312,300,239]	0	hSpCas9	negative selection	2055098
169769364	169769387	3	+	26627737	HCT116	viability after 12 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	1.4132924426825482	[251]	[443,180,420]	9	hSpCas9	negative selection	2055099
169769463	169769486	3	-	26627737	HCT116	viability after 12 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.3329311485946117	[546]	[263,288,129]	-4	hSpCas9	negative selection	2055100
169767619	169767642	3	+	26627737	HCT116	viability after 15 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.9609769606903549	[265]	[204,305,368]	7	hSpCas9	negative selection	2137410
169767620	169767643	3	+	26627737	HCT116	viability after 15 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.14365180053175874	[541]	[321,312,215]	-1	hSpCas9	negative selection	2137411
169767748	169767771	3	+	26627737	HCT116	viability after 15 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.7416023726838663	[408]	[172,161,90]	-6	hSpCas9	negative selection	2137412
169769341	169769364	3	-	26627737	HCT116	viability after 15 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	0.3040995484879192	[516]	[526,286,305]	3	hSpCas9	negative selection	2137413
169769364	169769387	3	+	26627737	HCT116	viability after 15 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	0.8179817973584645	[251]	[364,176,236]	7	hSpCas9	negative selection	2137414
169769463	169769486	3	-	26627737	HCT116	viability after 15 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.08073094127959946	[546]	[497,154,262]	-1	hSpCas9	negative selection	2137415
169767619	169767642	3	+	26627737	HCT116	viability after 18 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.4814826448978149	[265]	[264,89,189]	4	hSpCas9	negative selection	2219725
169767620	169767643	3	+	26627737	HCT116	viability after 18 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.39677541433466995	[541]	[231,228,130]	-4	hSpCas9	negative selection	2219726
169767748	169767771	3	+	26627737	HCT116	viability after 18 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-1.5682978878310914	[408]	[55,96,43]	-8	hSpCas9	negative selection	2219727
169769341	169769364	3	-	26627737	HCT116	viability after 18 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	0.9514842812677804	[516]	[450,522,472]	7	hSpCas9	negative selection	2219728
169769364	169769387	3	+	26627737	HCT116	viability after 18 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	1.618726707142446	[251]	[591,159,384]	9	hSpCas9	negative selection	2219729
169769463	169769486	3	-	26627737	HCT116	viability after 18 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.04320240887923288	[546]	[416,199,201]	0	hSpCas9	negative selection	2219730
169769402	169769425	3	-	24336569	HL60	viability	AACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-1.0856157438993637	[347]	[346]	-7	hSpCas9	negative selection	2246513
169769414	169769437	3	-	24336569	HL60	viability	TTTATCTACCCGAACATTATCGG	ACTRT3	ENSG00000184378	0.800610174808413	[257]	[950]	6	hSpCas9	negative selection	2246514
169769419	169769442	3	+	24336569	HL60	viability	AATGTTCGGGTAGATAAACTGGG	ACTRT3	ENSG00000184378	3.7584954868606353	[24]	[715]	9	hSpCas9	negative selection	2246515
169769452	169769475	3	-	24336569	HL60	viability	TGATCAAGGCGGGCGTGGCTGGG	ACTRT3	ENSG00000184378	-0.9026729247366947	[1477]	[1672]	-7	hSpCas9	negative selection	2246516
169769457	169769480	3	-	24336569	HL60	viability	GGGAATGATCAAGGCGGGCGTGG	ACTRT3	ENSG00000184378	-0.4468314567811561	[294]	[457]	-4	hSpCas9	negative selection	2246517
169769462	169769485	3	-	24336569	HL60	viability	GGCTCGGGAATGATCAAGGCGGG	ACTRT3	ENSG00000184378	0.4323652232331642	[193]	[553]	4	hSpCas9	negative selection	2246518
169769477	169769500	3	-	24336569	HL60	viability	GTGGTGATCGACAACGGCTCGGG	ACTRT3	ENSG00000184378	0.552630107423139	[432]	[1343]	5	hSpCas9	negative selection	2246519
169769483	169769506	3	-	24336569	HL60	viability	CTACCGGTGGTGATCGACAACGG	ACTRT3	ENSG00000184378	-2.0400936662090356	[549]	[282]	-9	hSpCas9	negative selection	2246520
169769493	169769516	3	+	24336569	HL60	viability	TCACCACCGGTAGCTGGCAGTGG	ACTRT3	ENSG00000184378	-0.07858446885270931	[1000]	[2005]	0	hSpCas9	negative selection	2246521
169769499	169769522	3	-	24336569	HL60	viability	CATGAACCACTGCCAGCTACCGG	ACTRT3	ENSG00000184378	-1.0967106894605134	[760]	[752]	-7	hSpCas9	negative selection	2246522
169769402	169769425	3	-	24336569	KBM7	viability	AACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	0.2184817294665118	[97]	[310]	2	hSpCas9	negative selection	2313690
169769414	169769437	3	-	24336569	KBM7	viability	TTTATCTACCCGAACATTATCGG	ACTRT3	ENSG00000184378	1.5501216873615293	[156]	[1253]	9	hSpCas9	negative selection	2313691
169769419	169769442	3	+	24336569	KBM7	viability	AATGTTCGGGTAGATAAACTGGG	ACTRT3	ENSG00000184378	0.7348367490766269	[229]	[1043]	6	hSpCas9	negative selection	2313692
169769452	169769475	3	-	24336569	KBM7	viability	TGATCAAGGCGGGCGTGGCTGGG	ACTRT3	ENSG00000184378	0.04385013856732156	[907]	[2552]	0	hSpCas9	negative selection	2313693
169769457	169769480	3	-	24336569	KBM7	viability	GGGAATGATCAAGGCGGGCGTGG	ACTRT3	ENSG00000184378	-0.660050904086638	[470]	[812]	-5	hSpCas9	negative selection	2313694
169769462	169769485	3	-	24336569	KBM7	viability	GGCTCGGGAATGATCAAGGCGGG	ACTRT3	ENSG00000184378	-0.3298013965319029	[481]	[1045]	-3	hSpCas9	negative selection	2313695
169769477	169769500	3	-	24336569	KBM7	viability	GTGGTGATCGACAACGGCTCGGG	ACTRT3	ENSG00000184378	0.6385500796326418	[381]	[1621]	6	hSpCas9	negative selection	2313696
169769483	169769506	3	-	24336569	KBM7	viability	CTACCGGTGGTGATCGACAACGG	ACTRT3	ENSG00000184378	0.11115176259909394	[406]	[1198]	1	hSpCas9	negative selection	2313697
169769493	169769516	3	+	24336569	KBM7	viability	TCACCACCGGTAGCTGGCAGTGG	ACTRT3	ENSG00000184378	0.14586977006010216	[564]	[1704]	1	hSpCas9	negative selection	2313698
169769499	169769522	3	-	24336569	KBM7	viability	CATGAACCACTGCCAGCTACCGG	ACTRT3	ENSG00000184378	-0.2675709442844121	[300]	[681]	-2	hSpCas9	negative selection	2313699
169769483	169769506	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACCGGTGGTGATCGACAACGG	ACTRT3	ENSG00000184378	0.507691511323598	[1,2]	[3,2]	9	hSpCas9	positive selection	2968781
169769374	169769397	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAGCCCGCCCTGGGCCGCGCGG	ACTRT3	ENSG00000184378	-0.37103229449762365	[2,1]	[0,1]	-5	hSpCas9	positive selection	2968782
169768340	169768363	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTCCTTACAGTTACCCAGTGG	ACTRT3	ENSG00000184378	0.43841563035021675	[5,5]	[5,6]	8	hSpCas9	positive selection	2968783
169769361	169769384	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.16512232302079452	[3,3]	[3,2]	3	hSpCas9	positive selection	2968784
169769483	169769506	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACCGGTGGTGATCGACAACGG	ACTRT3	ENSG00000184378	-0.17628929386899073	[1,1]	[0,1]	-3	hSpCas9	positive selection	3036639
169769374	169769397	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAGCCCGCCCTGGGCCGCGCGG	ACTRT3	ENSG00000184378	0.8129004431063198	[2,2]	[3,3]	9	hSpCas9	positive selection	3036640
169768340	169768363	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTCCTTACAGTTACCCAGTGG	ACTRT3	ENSG00000184378	0.118066586152768	[5,5]	[4,3]	2	hSpCas9	positive selection	3036641
169769361	169769384	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.1597051610291718	[3,3]	[4,1]	3	hSpCas9	positive selection	3036642
169767619	169767642		+	24336571	A375	resistance to PLX after 7 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.31829173957245815	[17,14]	[19,20]	8	hSpCas9	positive selection	3160294
169769466	169769489		-	24336571	A375	resistance to PLX after 7 days	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.020178889638275632	[10,6]	[7,9]	0	hSpCas9	positive selection	3160305
169769480	169769503		+	24336571	A375	resistance to PLX after 7 days	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.15350370984737183	[19,15]	[20,17]	5	hSpCas9	positive selection	3160316
169769361	169769384		-	24336571	A375	resistance to PLX after 7 days	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.15907159008859273	[7,8]	[8,9]	5	hSpCas9	positive selection	3160327
169768324	169768347		+	24336571	A375	resistance to PLX after 7 days	GTAATGAGACCACGCTCCACTGG	ACTRT3	ENSG00000184378	-0.07405367930976248	[22,23]	[24,19]	-2	hSpCas9	positive selection	3160338
169767749	169767772		-	24336571	A375	resistance to PLX after 7 days	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.0312780552484247	[18,15]	[15,17]	-1	hSpCas9	positive selection	3160349
169767619	169767642		+	24336571	A375	resistance to PLX after 14 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	2.2075265895813594	[23,12]	[37,43]	9	hSpCas9	positive selection	3218087
169769466	169769489		-	24336571	A375	resistance to PLX after 14 days	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-0.2939413905169853	[7,4]	[1,1]	-3	hSpCas9	positive selection	3218098
169769480	169769503		+	24336571	A375	resistance to PLX after 14 days	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.3877080510130698	[20,14]	[10,10]	4	hSpCas9	positive selection	3218109
169769361	169769384		-	24336571	A375	resistance to PLX after 14 days	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.9157300568827877	[6,9]	[7,6]	7	hSpCas9	positive selection	3218120
169768324	169768347		+	24336571	A375	resistance to PLX after 14 days	GTAATGAGACCACGCTCCACTGG	ACTRT3	ENSG00000184378	-0.255392983675384	[20,29]	[7,11]	-3	hSpCas9	positive selection	3218131
169767749	169767772		-	24336571	A375	resistance to PLX after 14 days	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.4916374204735571	[28,19]	[5,8]	-6	hSpCas9	positive selection	3218142
169767619	169767642		+	24336571	A375	viability after 7 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.376888559556767	[12]	[17,14]	6	hSpCas9	negative selection	3275880
169769466	169769489		-	24336571	A375	viability after 7 days	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.4283272791672127	[6]	[10,6]	6	hSpCas9	negative selection	3275891
169769480	169769503		+	24336571	A375	viability after 7 days	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.1502513215786616	[20]	[19,15]	-2	hSpCas9	negative selection	3275902
169769361	169769384		-	24336571	A375	viability after 7 days	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.2803882464523759	[7]	[7,8]	4	hSpCas9	negative selection	3275913
169768324	169768347		+	24336571	A375	viability after 7 days	GTAATGAGACCACGCTCCACTGG	ACTRT3	ENSG00000184378	0.29444131149540786	[19]	[22,23]	4	hSpCas9	negative selection	3275924
169767749	169767772		-	24336571	A375	viability after 7 days	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	0.3524839580972437	[13]	[18,15]	5	hSpCas9	negative selection	3275935
169767619	169767642		+	24336571	A375	viability after 14 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.581770626580885	[12]	[23,12]	7	hSpCas9	negative selection	3333673
169769466	169769489		-	24336571	A375	viability after 14 days	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.04043790541209169	[6]	[7,4]	0	hSpCas9	negative selection	3333684
169769480	169769503		+	24336571	A375	viability after 14 days	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.08451042546463883	[20]	[20,14]	-1	hSpCas9	negative selection	3333695
169769361	169769384		-	24336571	A375	viability after 14 days	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.2712422125172729	[7]	[6,9]	3	hSpCas9	negative selection	3333706
169768324	169768347		+	24336571	A375	viability after 14 days	GTAATGAGACCACGCTCCACTGG	ACTRT3	ENSG00000184378	0.42680079231391743	[19]	[20,29]	5	hSpCas9	negative selection	3333717
169767749	169767772		-	24336571	A375	viability after 14 days	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	0.8636412746443697	[13]	[28,19]	9	hSpCas9	negative selection	3333728
169769480	169769503	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.9537842014855419	[76,80]	[0,0]	4	hSpCas9	positive selection	3335465
169769466	169769489	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	2.6751165711173126	[16,30]	[0,0]	8	hSpCas9	positive selection	3335466
169767619	169767642	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.7226453080603473	[247,256]	[0,0]	-5	hSpCas9	positive selection	3335467
169767749	169767772	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.9810785278792439	[301,301]	[0,0]	-6	hSpCas9	positive selection	3354713
169769483	169769506	3	-	26780180	HT29	viability (Avana library 4 designs)	CTACCGGTGGTGATCGACAACGG	ACTRT3	ENSG00000184378	3.7430613559107	[]	[]	9	hSpCas9	negative selection	3404731
169769373	169769396	3	+	26780180	HT29	viability (Avana library 4 designs)	CTAGCCCGCCCTGGGCCGCGCGG	ACTRT3	ENSG00000184378	0.65349140230452	[]	[]	2	hSpCas9	negative selection	3404732
169768340	169768363	3	-	26780180	HT29	viability (Avana library 4 designs)	CTTTCCTTACAGTTACCCAGTGG	ACTRT3	ENSG00000184378	-0.486366439259716	[]	[]	-7	hSpCas9	negative selection	3404733
169769361	169769384	3	-	26780180	HT29	viability (Avana library 4 designs)	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	2.02976595326957	[]	[]	7	hSpCas9	negative selection	3404734
169768340	169768363	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTCCTTACAGTTACCCAGTGG	ACTRT3	ENSG00000184378	-1.2431001275968	[]	[]	-1	hSpCas9	negative selection	3476411
169769483	169769506	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCGGTGGTGATCGACAACGG	ACTRT3	ENSG00000184378	4.05704203174656	[]	[]	6	hSpCas9	negative selection	3476412
169769361	169769384	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	4.65621373082777	[]	[]	7	hSpCas9	negative selection	3476413
169769373	169769396	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGCCCGCCCTGGGCCGCGCGG	ACTRT3	ENSG00000184378	8.35190279047193	[]	[]	9	hSpCas9	negative selection	3476414
169769360	169769383	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCGGGCTAGAACTCTGCGTGGG	ACTRT3	ENSG00000184378	0.214135228348547	[]	[]	0	hSpCas9	negative selection	3476415
169768018	169768041	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCAGTTGCTGCACACCATGAGG	ACTRT3	ENSG00000184378	4.23895716735709	[]	[]	7	hSpCas9	negative selection	3476416
169768340	169768363	3	-	26780180	A375	viability (Avana lentiGuide)	CTTTCCTTACAGTTACCCAGTGG	ACTRT3	ENSG00000184378	-5.81274242190819	[]	[]	-8	hSpCas9	negative selection	3585070
169769483	169769506	3	-	26780180	A375	viability (Avana lentiGuide)	CTACCGGTGGTGATCGACAACGG	ACTRT3	ENSG00000184378	-2.81643347186703	[]	[]	-5	hSpCas9	negative selection	3585071
169769361	169769384	3	-	26780180	A375	viability (Avana lentiGuide)	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	2.9794844029911	[]	[]	3	hSpCas9	negative selection	3585072
169769373	169769396	3	+	26780180	A375	viability (Avana lentiGuide)	CTAGCCCGCCCTGGGCCGCGCGG	ACTRT3	ENSG00000184378	-2.33273018583354	[]	[]	-4	hSpCas9	negative selection	3585073
169769360	169769383	3	-	26780180	A375	viability (Avana lentiGuide)	GGCGGGCTAGAACTCTGCGTGGG	ACTRT3	ENSG00000184378	7.74883097187514	[]	[]	6	hSpCas9	negative selection	3585074
169768018	169768041	3	+	26780180	A375	viability (Avana lentiGuide)	TCCAGTTGCTGCACACCATGAGG	ACTRT3	ENSG00000184378	-2.31427756501954	[]	[]	-4	hSpCas9	negative selection	3585075
169768340	169768363	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTCCTTACAGTTACCCAGTGG	ACTRT3	ENSG00000184378	-0.1546982852302339	[6]	[5,5]	-3	hSpCas9	positive selection	3693729
169769483	169769506	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCGGTGGTGATCGACAACGG	ACTRT3	ENSG00000184378	0.24461437556660004	[4]	[5,5]	7	hSpCas9	positive selection	3693730
169769361	169769384	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.2940859234889129	[4]	[6,5]	8	hSpCas9	positive selection	3693731
169769373	169769396	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGCCCGCCCTGGGCCGCGCGG	ACTRT3	ENSG00000184378	0.60621818912206	[3]	[5,5]	9	hSpCas9	positive selection	3693732
169769360	169769383	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCGGGCTAGAACTCTGCGTGGG	ACTRT3	ENSG00000184378	0.19102299202786927	[4]	[4,5]	5	hSpCas9	positive selection	3693733
169768018	169768041	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCAGTTGCTGCACACCATGAGG	ACTRT3	ENSG00000184378	0.27651242503621976	[4]	[5,5]	7	hSpCas9	positive selection	3693734
169768340	169768363	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTCCTTACAGTTACCCAGTGG	ACTRT3	ENSG00000184378	0.34295879844634825	[6]	[7,6]	8	hSpCas9	positive selection	3802336
169769483	169769506	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCGGTGGTGATCGACAACGG	ACTRT3	ENSG00000184378	-0.46537665381660903	[4]	[2,1]	-6	hSpCas9	positive selection	3802337
169769361	169769384	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.27345593151437775	[5]	[6,5]	7	hSpCas9	positive selection	3802338
169769373	169769396	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGCCCGCCCTGGGCCGCGCGG	ACTRT3	ENSG00000184378	0.0869888005153977	[3]	[3,3]	2	hSpCas9	positive selection	3802339
169769360	169769383	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCGGGCTAGAACTCTGCGTGGG	ACTRT3	ENSG00000184378	-0.06440740116248149	[5]	[3,5]	-1	hSpCas9	positive selection	3802340
169768018	169768041	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCAGTTGCTGCACACCATGAGG	ACTRT3	ENSG00000184378	0.18321659433367965	[5]	[4,5]	4	hSpCas9	positive selection	3802341
169767619	169767642	3	+	26780180	A375	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.472869235891043	[]	[]	1	hSpCas9	negative selection	3910938
169769466	169769489	3	-	26780180	A375	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.660628939090553	[]	[]	2	hSpCas9	negative selection	3910939
169769364	169769387	3	+	26780180	A375	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	1.06381467923829	[]	[]	5	hSpCas9	negative selection	3910940
169769480	169769503	3	+	26780180	A375	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	1.73748166588766	[]	[]	9	hSpCas9	negative selection	3910941
169769361	169769384	3	-	26780180	A375	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	1.0417899003079	[]	[]	5	hSpCas9	negative selection	3910942
169767749	169767772	3	-	26780180	A375	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	1.13629308851171	[]	[]	6	hSpCas9	negative selection	3910943
169767619	169767642	3	+	26780180	HT29	viability (GeCKOv2 library)	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	1.76979001872168	[]	[]	8	hSpCas9	negative selection	4018904
169769466	169769489	3	-	26780180	HT29	viability (GeCKOv2 library)	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.433578184801131	[]	[]	1	hSpCas9	negative selection	4018905
169769364	169769387	3	+	26780180	HT29	viability (GeCKOv2 library)	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	2.30163891494975	[]	[]	9	hSpCas9	negative selection	4018906
169769480	169769503	3	+	26780180	HT29	viability (GeCKOv2 library)	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	1.90553745278146	[]	[]	9	hSpCas9	negative selection	4018907
169769361	169769384	3	-	26780180	HT29	viability (GeCKOv2 library)	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	1.10906552112128	[]	[]	5	hSpCas9	negative selection	4018908
169767749	169767772	3	-	26780180	HT29	viability (GeCKOv2 library)	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	0.847470078335118	[]	[]	3	hSpCas9	negative selection	4018909
169767619	169767642	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.30382238228362	[3]	[1,5]	7	hSpCas9	positive selection	4188365
169769466	169769489	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-0.20908971993491596	[3]	[2,0]	-5	hSpCas9	positive selection	4188376
169769480	169769503	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.18058906837810837	[4]	[2,3]	4	hSpCas9	positive selection	4188387
169769361	169769384	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.28667528422285676	[3]	[2,2]	7	hSpCas9	positive selection	4188398
169768324	169768347	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTAATGAGACCACGCTCCACTGG	ACTRT3	ENSG00000184378	-0.17841671887549154	[4]	[2,3]	-4	hSpCas9	positive selection	4188409
169767749	169767772	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	0.10532424284498616	[3]	[2,2]	2	hSpCas9	positive selection	4188420
169767619	169767642	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	1.4018901599677414	[3]	[5,3,2,3]	9	hSpCas9	positive selection	4252387
169769466	169769489	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.9381206834494878	[2]	[3,3,1,0]	6	hSpCas9	positive selection	4252398
169769480	169769503	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.04058677786227674	[3]	[3,1,1,0]	0	hSpCas9	positive selection	4252409
169769361	169769384	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.7524201428791497	[2]	[0,0,0,0]	-9	hSpCas9	positive selection	4252420
169768324	169768347	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTAATGAGACCACGCTCCACTGG	ACTRT3	ENSG00000184378	1.1129719095797965	[4]	[3,2,4,4]	8	hSpCas9	positive selection	4252431
169767749	169767772	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.42357864321674765	[4]	[0,0,2,0]	-6	hSpCas9	positive selection	4252442
169769480	169769503	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.5541330173043355	[2]	[2,0]	-8	hSpCas9	positive selection	4254386
169769466	169769489	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-0.16381098459359777	[0]	[0,0]	-3	hSpCas9	positive selection	4254387
169767619	169767642	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.07060798027840176	[3]	[3,2]	1	hSpCas9	positive selection	4254388
169767749	169767772	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	0.012938155376691796	[4]	[4,2]	0	hSpCas9	positive selection	4318669
169769361	169769384	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.18744223551031336	[1]	[1,0]	-4	hSpCas9	positive selection	4318670
169769364	169769387	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.12228436125826292	[3]	[3,1]	-2	hSpCas9	positive selection	4318671
169768141	169768163	3	+	27760321	OCIAML3	viability	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	0.7797070238238268	[110,103]	[110,187]	8	hSpCas9	negative selection	4375976
169768192	169768214	3	+	27760321	OCIAML3	viability	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.6551056502080268	[1086,916]	[1021,1499]	7	hSpCas9	negative selection	4375977
169768313	169768335	3	-	27760321	OCIAML3	viability	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.47162699060274826	[469,291]	[390,426]	5	hSpCas9	negative selection	4375978
169769338	169769360	3	-	27760321	OCIAML3	viability	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.17801195084411858	[616,476]	[430,544]	2	hSpCas9	negative selection	4375979
169769402	169769424	3	-	27760321	OCIAML3	viability	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.17220972469963558	[834,759]	[524,589]	-2	hSpCas9	negative selection	4375980
169768141	169768163	3	+	27760321	OCIAML2	viability	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-1.2915349978940553	[110,103]	[38,30]	-8	hSpCas9	negative selection	4459439
169768192	169768214	3	+	27760321	OCIAML2	viability	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.12905350625334777	[1086,916]	[795,997]	1	hSpCas9	negative selection	4459440
169768313	169768335	3	-	27760321	OCIAML2	viability	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	-0.331917242958054	[469,291]	[243,236]	-4	hSpCas9	negative selection	4459441
169769338	169769360	3	-	27760321	OCIAML2	viability	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.3455148650034623	[616,476]	[236,488]	-4	hSpCas9	negative selection	4459442
169769402	169769424	3	-	27760321	OCIAML2	viability	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.33090229920927317	[834,759]	[525,494]	-4	hSpCas9	negative selection	4459443
169768141	169768163	3	+	27760321	MV411	viability	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-2.2056566737231704	[110,103]	[0,36]	-8	hSpCas9	negative selection	4542902
169768192	169768214	3	+	27760321	MV411	viability	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.590837282714441	[1086,916]	[767,1328]	4	hSpCas9	negative selection	4542903
169768313	169768335	3	-	27760321	MV411	viability	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	1.4031368590148596	[469,291]	[876,319]	8	hSpCas9	negative selection	4542904
169769338	169769360	3	-	27760321	MV411	viability	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.2219068493608377	[616,476]	[351,516]	1	hSpCas9	negative selection	4542905
169769402	169769424	3	-	27760321	MV411	viability	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	0.10920485750189035	[834,759]	[237,1061]	0	hSpCas9	negative selection	4542906
169768141	169768163	3	+	27760321	HL60	viability	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-0.954455259272136	[110,103]	[6,85]	-7	hSpCas9	negative selection	4626365
169768192	169768214	3	+	27760321	HL60	viability	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.67269990522245	[1086,916]	[1347,1248]	7	hSpCas9	negative selection	4626366
169768313	169768335	3	-	27760321	HL60	viability	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.5461854480631853	[469,291]	[504,385]	6	hSpCas9	negative selection	4626367
169769338	169769360	3	-	27760321	HL60	viability	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.2840625461097418	[616,476]	[490,229]	-3	hSpCas9	negative selection	4626368
169769402	169769424	3	-	27760321	HL60	viability	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	0.10141936979964139	[834,759]	[681,715]	1	hSpCas9	negative selection	4626369
169768141	169768163	3	+	27760321	HT1080	viability	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-5.203379174735446	[103,80]	[0,0]	-8	hSpCas9	negative selection	4709828
169768192	169768214	3	+	27760321	HT1080	viability	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.9114704373322147	[916,715]	[502,730]	5	hSpCas9	negative selection	4709829
169768313	169768335	3	-	27760321	HT1080	viability	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.6845299666047582	[291,227]	[207,120]	3	hSpCas9	negative selection	4709830
169769338	169769360	3	-	27760321	HT1080	viability	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.6029687174637745	[476,371]	[147,375]	3	hSpCas9	negative selection	4709831
169769402	169769424	3	-	27760321	HT1080	viability	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.09135101154529457	[759,592]	[93,426]	0	hSpCas9	negative selection	4709832
169768141	169768163	3	+	27760321	HT29	viability after 7 days	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	0.2901030382320271	[103,80]	[117,197,116]	4	hSpCas9	negative selection	4793291
169768192	169768214	3	+	27760321	HT29	viability after 7 days	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.22861604230223453	[916,715]	[1342,986,1369]	3	hSpCas9	negative selection	4793292
169768313	169768335	3	-	27760321	HT29	viability after 7 days	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.23403766832234477	[291,227]	[307,471,386]	3	hSpCas9	negative selection	4793293
169769338	169769360	3	-	27760321	HT29	viability after 7 days	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.1383217105244761	[476,371]	[760,588,477]	2	hSpCas9	negative selection	4793294
169769402	169769424	3	-	27760321	HT29	viability after 7 days	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.1443180981345107	[759,592]	[689,933,723]	-2	hSpCas9	negative selection	4793295
169768141	169768163	3	+	27760321	HT29	viability after 25 days	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-1.6814275107565346	[103,80]	[27,21,50]	-7	hSpCas9	negative selection	4876754
169768192	169768214	3	+	27760321	HT29	viability after 25 days	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.4656359693984229	[916,715]	[1229,1163,1494]	5	hSpCas9	negative selection	4876755
169768313	169768335	3	-	27760321	HT29	viability after 25 days	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.24742220727249656	[291,227]	[348,294,420]	2	hSpCas9	negative selection	4876756
169769338	169769360	3	-	27760321	HT29	viability after 25 days	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.27036481530648326	[476,371]	[503,510,762]	3	hSpCas9	negative selection	4876757
169769402	169769424	3	-	27760321	HT29	viability after 25 days	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.3411031040160255	[759,592]	[546,607,686]	-3	hSpCas9	negative selection	4876758
169768141	169768163	3	+	27760321	HT29	viability after 22 days	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-0.3804804479749553	[103,80]	[128,47,67]	-4	hSpCas9	negative selection	4960217
169768192	169768214	3	+	27760321	HT29	viability after 22 days	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.32688702360121624	[916,715]	[1095,1304,1152]	3	hSpCas9	negative selection	4960218
169768313	169768335	3	-	27760321	HT29	viability after 22 days	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.0922183063314908	[291,227]	[238,346,377]	0	hSpCas9	negative selection	4960219
169769338	169769360	3	-	27760321	HT29	viability after 22 days	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.4294766225487273	[476,371]	[927,425,620]	4	hSpCas9	negative selection	4960220
169769402	169769424	3	-	27760321	HT29	viability after 22 days	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.4983604221684567	[759,592]	[396,618,649]	-4	hSpCas9	negative selection	4960221
169768141	169768163	3	+	27760321	HT29	viability after 19 days	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-0.09003545574387362	[103,80]	[114,12,168]	-1	hSpCas9	negative selection	5043680
169768192	169768214	3	+	27760321	HT29	viability after 19 days	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.2713349701190553	[916,715]	[1377,828,1196]	2	hSpCas9	negative selection	5043681
169768313	169768335	3	-	27760321	HT29	viability after 19 days	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.2117798941996401	[291,227]	[354,199,473]	2	hSpCas9	negative selection	5043682
169769338	169769360	3	-	27760321	HT29	viability after 19 days	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.559564804633475	[476,371]	[626,720,785]	5	hSpCas9	negative selection	5043683
169769402	169769424	3	-	27760321	HT29	viability after 19 days	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.22097587011652553	[759,592]	[910,445,659]	-2	hSpCas9	negative selection	5043684
169768141	169768163	3	+	27760321	HT29	viability after 16 days	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-0.24401588932966867	[103,80]	[53,123,79]	-3	hSpCas9	negative selection	5127143
169768192	169768214	3	+	27760321	HT29	viability after 16 days	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.3986526584803316	[916,715]	[1542,922,1185]	4	hSpCas9	negative selection	5127144
169768313	169768335	3	-	27760321	HT29	viability after 16 days	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.20297053943916166	[291,227]	[360,370,273]	2	hSpCas9	negative selection	5127145
169769338	169769360	3	-	27760321	HT29	viability after 16 days	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.5963237958736699	[476,371]	[677,874,592]	7	hSpCas9	negative selection	5127146
169769402	169769424	3	-	27760321	HT29	viability after 16 days	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.6487891874630856	[759,592]	[468,552,422]	-6	hSpCas9	negative selection	5127147
169768141	169768163	3	+	27760321	HT29	viability after 13 days	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-0.7190626108523674	[103,80]	[81,73,40]	-6	hSpCas9	negative selection	5210606
169768192	169768214	3	+	27760321	HT29	viability after 13 days	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.5846699082462881	[916,715]	[1317,1714,1239]	7	hSpCas9	negative selection	5210607
169768313	169768335	3	-	27760321	HT29	viability after 13 days	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.36211241499753244	[291,227]	[328,477,357]	4	hSpCas9	negative selection	5210608
169769338	169769360	3	-	27760321	HT29	viability after 13 days	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.40840330714181683	[476,371]	[759,659,546]	5	hSpCas9	negative selection	5210609
169769402	169769424	3	-	27760321	HT29	viability after 13 days	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.1733899104576626	[759,592]	[701,695,689]	-2	hSpCas9	negative selection	5210610
169768141	169768163	3	+	27760321	HT29	viability after 10 days	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-0.6559657127521423	[103,80]	[82,91,45]	-6	hSpCas9	negative selection	5294069
169768192	169768214	3	+	27760321	HT29	viability after 10 days	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.18512431453550904	[916,715]	[1166,1115,1191]	2	hSpCas9	negative selection	5294070
169768313	169768335	3	-	27760321	HT29	viability after 10 days	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.2753439178507009	[291,227]	[365,251,552]	3	hSpCas9	negative selection	5294071
169769338	169769360	3	-	27760321	HT29	viability after 10 days	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.41592912478252075	[476,371]	[850,699,572]	5	hSpCas9	negative selection	5294072
169769402	169769424	3	-	27760321	HT29	viability after 10 days	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	-0.2513844483772476	[759,592]	[545,790,791]	-3	hSpCas9	negative selection	5294073
169768141	169768163	3	+	27760321	MOLM13	viability	GCCTGGATGGACATATAGAAGG	ACTRT3	ENSG00000184378	-0.9085681519846505	[110,103]	[0,58]	-5	hSpCas9	negative selection	5377532
169768192	169768214	3	+	27760321	MOLM13	viability	TCCGTGATCTGTTGCCGGTTGG	ACTRT3	ENSG00000184378	0.5067895842170826	[1086,916]	[1192,465]	3	hSpCas9	negative selection	5377533
169768313	169768335	3	-	27760321	MOLM13	viability	GGTCTCATTACTTCATGGGAGG	ACTRT3	ENSG00000184378	0.6231887614538908	[469,291]	[280,363]	4	hSpCas9	negative selection	5377534
169769338	169769360	3	-	27760321	MOLM13	viability	CGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.7541044955047901	[616,476]	[313,68]	-5	hSpCas9	negative selection	5377535
169769402	169769424	3	-	27760321	MOLM13	viability	ACATTATCGGCCGCGCCAAGGG	ACTRT3	ENSG00000184378	0.5313076794287511	[834,759]	[704,602]	3	hSpCas9	negative selection	5377536
169769480	169769503	3	+	27661255	K562	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.18690030313432504	[1780,1892]	[1985,1397]	6	dCas9-KRAB	negative selection	5460804
169769163	169769186	3	-	27661255	K562	viability	GCAGGAAAGGACCCCAAAGGAGG	ACTRT3	ENSG00000184378	-0.16459487937765638	[663,638]	[462,465]	-5	dCas9-KRAB	negative selection	5460805
169769496	169769519	3	-	27661255	K562	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	-0.14274760220035665	[208,151]	[146,117]	-5	dCas9-KRAB	negative selection	5460806
169769555	169769578	3	-	27661255	K562	viability	GGCCGAGCCCGTAGCTAGAGCGG	ACTRT3	ENSG00000184378	0.0018369919829710757	[721,722]	[660,506]	0	dCas9-KRAB	negative selection	5460807
169769480	169769503	3	+	27260156	BXPC3	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.08763096964127304	[328]	[358,278,423,409]	2	hSpCas9	negative selection	5526846
169769466	169769489	3	-	27260156	BXPC3	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.17460494817160876	[52]	[46,43,84,78]	4	hSpCas9	negative selection	5526847
169767619	169767642	3	+	27260156	BXPC3	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.00020373781046256756	[905]	[1016,796,913,1070]	0	hSpCas9	negative selection	5526848
169767749	169767772	3	-	27260156	BXPC3	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.26904270186201806	[1185]	[939,1144,973,1054]	-6	hSpCas9	negative selection	5591129
169769361	169769384	3	-	27260156	BXPC3	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.7392429924299222	[137]	[80,101,79,80]	-9	hSpCas9	negative selection	5591130
169769364	169769387	3	+	27260156	BXPC3	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.4156187721303358	[850]	[526,697,697,766]	-7	hSpCas9	negative selection	5591131
169769480	169769503	3	+	27260156	A673	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.06264014938537832	[328]	[344,358,447,354]	-1	hSpCas9	negative selection	5648097
169769466	169769489	3	-	27260156	A673	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.08235395052769423	[52]	[52,83,52,77]	2	hSpCas9	negative selection	5648098
169767619	169767642	3	+	27260156	A673	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.07435061635199458	[905]	[1261,946,1257,1128]	1	hSpCas9	negative selection	5648099
169767749	169767772	3	-	27260156	A673	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.28803010089242087	[1185]	[1377,1143,1110,1048]	-6	hSpCas9	negative selection	5712380
169769361	169769384	3	-	27260156	A673	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.38655060556000986	[137]	[128,126,153,94]	-7	hSpCas9	negative selection	5712381
169769364	169769387	3	+	27260156	A673	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.6333933824488795	[850]	[771,563,583,733]	-9	hSpCas9	negative selection	5712382
169769480	169769503	3	+	27260156	A375	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.3160666853771825	[328]	[478,603,467,388]	4	hSpCas9	negative selection	5769348
169769466	169769489	3	-	27260156	A375	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.19014738405443898	[52]	[112,111,26,39]	2	hSpCas9	negative selection	5769349
169767619	169767642	3	+	27260156	A375	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.5426587745677657	[905]	[1393,2146,1854,921]	7	hSpCas9	negative selection	5769350
169767749	169767772	3	-	27260156	A375	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.03765676505668658	[1185]	[1309,1513,1412,1196]	0	hSpCas9	negative selection	5833631
169769361	169769384	3	-	27260156	A375	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.1328659439015012	[137]	[189,170,146,89]	-2	hSpCas9	negative selection	5833632
169769364	169769387	3	+	27260156	A375	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.24818894818621873	[850]	[852,893,802,805]	-4	hSpCas9	negative selection	5833633
169769480	169769503	3	+	27260156	COLO741	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.15070634281335782	[328]	[521,287,339]	-3	hSpCas9	negative selection	5890599
169769466	169769489	3	-	27260156	COLO741	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-0.15626378832778487	[52]	[57,77,46]	-3	hSpCas9	negative selection	5890600
169767619	169767642	3	+	27260156	COLO741	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.22844200871659648	[905]	[1494,1419,1175]	5	hSpCas9	negative selection	5890601
169767749	169767772	3	-	27260156	COLO741	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.3943524064351275	[1185]	[1131,1343,990]	-7	hSpCas9	negative selection	5954882
169769361	169769384	3	-	27260156	COLO741	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.008228522500407509	[137]	[312,104,122]	0	hSpCas9	negative selection	5954883
169769364	169769387	3	+	27260156	COLO741	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.5643431207825478	[850]	[900,692,631]	-8	hSpCas9	negative selection	5954884
169769480	169769503	3	+	27260156	CAL120	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.5165773848683167	[328]	[363,211,293]	-6	hSpCas9	negative selection	6011850
169769466	169769489	3	-	27260156	CAL120	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-0.04172128152673649	[52]	[52,99,37]	0	hSpCas9	negative selection	6011851
169767619	169767642	3	+	27260156	CAL120	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.056402857654412886	[905]	[1141,1100,1018]	-1	hSpCas9	negative selection	6011852
169767749	169767772	3	-	27260156	CAL120	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.4050037656749066	[1185]	[1453,913,1027]	-5	hSpCas9	negative selection	6076133
169769361	169769384	3	-	27260156	CAL120	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.508194520435314	[137]	[72,105,174]	-6	hSpCas9	negative selection	6076134
169769364	169769387	3	+	27260156	CAL120	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	0.03891514468485591	[850]	[1909,555,923]	0	hSpCas9	negative selection	6076135
169769480	169769503	3	+	27260156	CADOES1	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.07639300049310455	[328]	[353,321,302,310]	1	hSpCas9	negative selection	6133101
169769466	169769489	3	-	27260156	CADOES1	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-0.7457658678100105	[52]	[29,28,43,13]	-8	hSpCas9	negative selection	6133102
169767619	169767642	3	+	27260156	CADOES1	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.1586508114597528	[905]	[985,976,942,852]	2	hSpCas9	negative selection	6133103
169767749	169767772	3	-	27260156	CADOES1	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.10550406162742165	[1185]	[981,839,1118,1164]	-2	hSpCas9	negative selection	6197384
169769361	169769384	3	-	27260156	CADOES1	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.3394374482071556	[137]	[77,98,96,132]	-5	hSpCas9	negative selection	6197385
169769364	169769387	3	+	27260156	CADOES1	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.3759170447607523	[850]	[428,719,741,546]	-6	hSpCas9	negative selection	6197386
169769480	169769503	3	+	27260156	EWS502	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.059038576212705474	[328]	[263,277,335,479]	-1	hSpCas9	negative selection	6254352
169769466	169769489	3	-	27260156	EWS502	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.1480604830381198	[52]	[39,88,60,59]	2	hSpCas9	negative selection	6254353
169767619	169767642	3	+	27260156	EWS502	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.1689550172677149	[905]	[1027,1026,1057,1215]	3	hSpCas9	negative selection	6254354
169767749	169767772	3	-	27260156	EWS502	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.3930664312179334	[1185]	[1031,792,980,1018]	-6	hSpCas9	negative selection	6318635
169769361	169769384	3	-	27260156	EWS502	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.11567973754687233	[137]	[82,208,147,202]	2	hSpCas9	negative selection	6318636
169769364	169769387	3	+	27260156	EWS502	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.6391407134790057	[850]	[431,572,559,779]	-7	hSpCas9	negative selection	6318637
169769480	169769503	3	+	27260156	EW8	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.3495362348766148	[328]	[265,443,227,430]	6	hSpCas9	negative selection	6375603
169769466	169769489	3	-	27260156	EW8	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.3280298672016464	[52]	[50,31,59,70]	6	hSpCas9	negative selection	6375604
169767619	169767642	3	+	27260156	EW8	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.05511740989483882	[905]	[779,682,693,677]	-1	hSpCas9	negative selection	6375605
169767749	169767772	3	-	27260156	EW8	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	0.038875931772607064	[1185]	[976,798,1203,927]	0	hSpCas9	negative selection	6439886
169769361	169769384	3	-	27260156	EW8	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.012035417065915821	[137]	[81,63,72,226]	0	hSpCas9	negative selection	6439887
169769364	169769387	3	+	27260156	EW8	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.5137024868332832	[850]	[421,470,349,702]	-7	hSpCas9	negative selection	6439888
169769480	169769503	3	+	27260156	CORL105	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.29063349630332697	[328]	[647,376,448,414]	5	hSpCas9	negative selection	6496854
169769466	169769489	3	-	27260156	CORL105	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.1649423713620095	[52]	[51,54,120,57]	3	hSpCas9	negative selection	6496855
169767619	169767642	3	+	27260156	CORL105	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.027126266395241183	[905]	[1080,936,1138,1024]	0	hSpCas9	negative selection	6496856
169767749	169767772	3	-	27260156	CORL105	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.18569209658420527	[1185]	[1109,1124,1715,1007]	-3	hSpCas9	negative selection	6561137
169769361	169769384	3	-	27260156	CORL105	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.46174481325182226	[137]	[179,79,84,121]	-7	hSpCas9	negative selection	6561138
169769364	169769387	3	+	27260156	CORL105	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.48578013646615126	[850]	[577,586,915,793]	-7	hSpCas9	negative selection	6561139
169769480	169769503	3	+	27260156	HS294T	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.6976878800605067	[328]	[104,256,352,99]	8	hSpCas9	negative selection	6618105
169769466	169769489	3	-	27260156	HS294T	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-0.6109966869572476	[52]	[8,12,8,24]	-7	hSpCas9	negative selection	6618106
169767619	169767642	3	+	27260156	HS294T	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.10277485197607172	[905]	[291,284,307,442]	-1	hSpCas9	negative selection	6618107
169767749	169767772	3	-	27260156	HS294T	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.22912836792016478	[1185]	[321,201,555,517]	-3	hSpCas9	negative selection	6682388
169769361	169769384	3	-	27260156	HS294T	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.3233810441412128	[137]	[50,97,62,52]	4	hSpCas9	negative selection	6682389
169769364	169769387	3	+	27260156	HS294T	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.20654116514143628	[850]	[345,270,252,259]	-3	hSpCas9	negative selection	6682390
169769480	169769503	3	+	27260156	HCC44	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.08317452610389664	[328]	[383,309,443,290]	-1	hSpCas9	negative selection	6739356
169769466	169769489	3	-	27260156	HCC44	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.8732256559660554	[52]	[157,33,108,150]	9	hSpCas9	negative selection	6739357
169767619	169767642	3	+	27260156	HCC44	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.18553452191564712	[905]	[1319,1023,1252,1105]	3	hSpCas9	negative selection	6739358
169767749	169767772	3	-	27260156	HCC44	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.13846007624160617	[1185]	[1160,1099,1728,981]	-2	hSpCas9	negative selection	6803639
169769361	169769384	3	-	27260156	HCC44	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.6399838647840386	[137]	[105,178,48,47]	-7	hSpCas9	negative selection	6803640
169769364	169769387	3	+	27260156	HCC44	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.41186031045771165	[850]	[690,585,905,751]	-6	hSpCas9	negative selection	6803641
169769480	169769503	3	+	27260156	G402	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.0920555170408005	[328]	[277,435,397,381]	-1	hSpCas9	negative selection	6860607
169769466	169769489	3	-	27260156	G402	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-0.5274841038604805	[52]	[2,58,86,25]	-6	hSpCas9	negative selection	6860608
169767619	169767642	3	+	27260156	G402	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.3089107463248183	[905]	[1932,1320,755,1532]	4	hSpCas9	negative selection	6860609
169767749	169767772	3	-	27260156	G402	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.021996893450702215	[1185]	[1748,1587,1482,954]	0	hSpCas9	negative selection	6924890
169769361	169769384	3	-	27260156	G402	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-1.084128287759154	[137]	[105,75,58,79]	-8	hSpCas9	negative selection	6924891
169769364	169769387	3	+	27260156	G402	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.6145345822078537	[850]	[815,568,516,814]	-6	hSpCas9	negative selection	6924892
169769480	169769503	3	+	27260156	L33	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.2614154472747052	[328]	[356,82,174,257]	-6	hSpCas9	negative selection	6981858
169769466	169769489	3	-	27260156	L33	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.1948618864094187	[52]	[35,28,28,89]	4	hSpCas9	negative selection	6981859
169767619	169767642	3	+	27260156	L33	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.12143066820649384	[905]	[803,323,530,891]	-3	hSpCas9	negative selection	6981860
169767749	169767772	3	-	27260156	L33	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.11951917370661547	[1185]	[1126,424,743,1018]	-3	hSpCas9	negative selection	7046141
169769361	169769384	3	-	27260156	L33	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.17359399428017253	[137]	[245,41,101,109]	4	hSpCas9	negative selection	7046142
169769364	169769387	3	+	27260156	L33	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.8212570432041052	[850]	[404,200,332,502]	-9	hSpCas9	negative selection	7046143
169769480	169769503	3	+	27260156	K562	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.31250336145460034	[328]	[305,385,137,134]	-4	hSpCas9	negative selection	7103109
169769466	169769489	3	-	27260156	K562	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	1.3894752431683106	[52]	[147,273,57,32]	9	hSpCas9	negative selection	7103110
169767619	169767642	3	+	27260156	K562	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.31052511883905665	[905]	[1249,1530,604,683]	4	hSpCas9	negative selection	7103111
169767749	169767772	3	-	27260156	K562	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.3574306563202567	[1185]	[806,1066,1095,376]	-4	hSpCas9	negative selection	7167392
169769361	169769384	3	-	27260156	K562	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.09402013323898828	[137]	[149,39,242,33]	-1	hSpCas9	negative selection	7167393
169769364	169769387	3	+	27260156	K562	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.4926752571916455	[850]	[842,409,523,401]	-5	hSpCas9	negative selection	7167394
169769480	169769503	3	+	27260156	HT29	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.11456863527530203	[328]	[432,435,385,245]	-2	hSpCas9	negative selection	7224360
169769466	169769489	3	-	27260156	HT29	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	1.2453832251590302	[52]	[128,114,155,198]	9	hSpCas9	negative selection	7224361
169767619	169767642	3	+	27260156	HT29	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.1925642429675457	[905]	[1294,1340,1318,1099]	4	hSpCas9	negative selection	7224362
169767749	169767772	3	-	27260156	HT29	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.29441970585016586	[1185]	[1168,1190,1503,868]	-5	hSpCas9	negative selection	7288643
169769361	169769384	3	-	27260156	HT29	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.9927793365930988	[137]	[116,47,59,107]	-8	hSpCas9	negative selection	7288644
169769364	169769387	3	+	27260156	HT29	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.7428697657033144	[850]	[678,743,517,550]	-8	hSpCas9	negative selection	7288645
169769480	169769503	3	+	27260156	MHHES1	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.4261857498883518	[328]	[538,589,384,482]	7	hSpCas9	negative selection	7345611
169769466	169769489	3	-	27260156	MHHES1	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-0.5408114169964358	[52]	[25,57,57,24]	-7	hSpCas9	negative selection	7345612
169767619	169767642	3	+	27260156	MHHES1	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.3074138517296193	[905]	[1356,1398,1086,1213]	5	hSpCas9	negative selection	7345613
169767749	169767772	3	-	27260156	MHHES1	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.1083016786761104	[1185]	[1341,1202,1258,1152]	-2	hSpCas9	negative selection	7409894
169769361	169769384	3	-	27260156	MHHES1	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.6345050005224624	[137]	[57,152,120,72]	-8	hSpCas9	negative selection	7409895
169769364	169769387	3	+	27260156	MHHES1	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.05803137137664849	[850]	[1145,1397,735,544]	-1	hSpCas9	negative selection	7409896
169769480	169769503	3	+	27260156	MEWO	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.04823792700459234	[328]	[389,240,337]	1	hSpCas9	negative selection	7466862
169769466	169769489	3	-	27260156	MEWO	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.46743102105210577	[52]	[90,69,48]	8	hSpCas9	negative selection	7466863
169767619	169767642	3	+	27260156	MEWO	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.21236458590662244	[905]	[1188,980,815]	4	hSpCas9	negative selection	7466864
169767749	169767772	3	-	27260156	MEWO	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.01762902323102633	[1185]	[1415,897,1036]	0	hSpCas9	negative selection	7531145
169769361	169769384	3	-	27260156	MEWO	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.24597243292380133	[137]	[104,74,145]	-5	hSpCas9	negative selection	7531146
169769364	169769387	3	+	27260156	MEWO	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.4077983509092406	[850]	[748,617,461]	-7	hSpCas9	negative selection	7531147
169769480	169769503	3	+	27260156	LNCAPCLONEFGC	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.25427939403567634	[328]	[277,142,304,287]	-4	hSpCas9	negative selection	7588113
169769466	169769489	3	-	27260156	LNCAPCLONEFGC	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.44261445483510364	[52]	[78,36,74,72]	7	hSpCas9	negative selection	7588114
169767619	169767642	3	+	27260156	LNCAPCLONEFGC	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.004967114453862775	[905]	[647,787,955,926]	0	hSpCas9	negative selection	7588115
169767749	169767772	3	-	27260156	LNCAPCLONEFGC	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.37750390548703994	[1185]	[940,694,1123,597]	-5	hSpCas9	negative selection	7652396
169769361	169769384	3	-	27260156	LNCAPCLONEFGC	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.21215581061104793	[137]	[63,56,115,199]	-3	hSpCas9	negative selection	7652397
169769364	169769387	3	+	27260156	LNCAPCLONEFGC	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.8685426399080115	[850]	[437,332,528,409]	-8	hSpCas9	negative selection	7652398
169769480	169769503	3	+	27260156	PANC0327	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.20774947001197175	[328]	[299,144,293,290]	-3	hSpCas9	negative selection	7709364
169769466	169769489	3	-	27260156	PANC0327	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.6909000625384278	[52]	[68,54,33,147]	8	hSpCas9	negative selection	7709365
169767619	169767642	3	+	27260156	PANC0327	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.2844428670029505	[905]	[543,596,865,634]	-4	hSpCas9	negative selection	7709366
169767749	169767772	3	-	27260156	PANC0327	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.9328381948416693	[1185]	[577,454,593,594]	-8	hSpCas9	negative selection	7773647
169769361	169769384	3	-	27260156	PANC0327	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.6786004869450091	[137]	[52,141,81,18]	-7	hSpCas9	negative selection	7773648
169769364	169769387	3	+	27260156	PANC0327	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.1273145738968795	[850]	[1097,495,741,490]	-2	hSpCas9	negative selection	7773649
169769480	169769503	3	+	27260156	NCIH2009	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.28397614107152913	[328]	[544,435,182]	-4	hSpCas9	negative selection	7830615
169769466	169769489	3	-	27260156	NCIH2009	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	-1.5449007897399287	[52]	[34,24,17]	-9	hSpCas9	negative selection	7830616
169767619	169767642	3	+	27260156	NCIH2009	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.03562320298365107	[905]	[1532,1173,1231]	0	hSpCas9	negative selection	7830617
169767749	169767772	3	-	27260156	NCIH2009	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.28847703309692396	[1185]	[1539,1360,1202]	-4	hSpCas9	negative selection	7894898
169769361	169769384	3	-	27260156	NCIH2009	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.6903414422876444	[137]	[117,61,178]	-7	hSpCas9	negative selection	7894899
169769364	169769387	3	+	27260156	NCIH2009	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.31112497399787065	[850]	[1045,996,846]	-4	hSpCas9	negative selection	7894900
169769480	169769503	3	+	27260156	NCIH1373	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.14870311601191877	[328]	[465,132,480,74]	-1	hSpCas9	negative selection	7951866
169769466	169769489	3	-	27260156	NCIH1373	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.23406730340449933	[52]	[176,18,12,24]	2	hSpCas9	negative selection	7951867
169767619	169767642	3	+	27260156	NCIH1373	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.2896076105239105	[905]	[798,709,795,271]	-3	hSpCas9	negative selection	7951868
169767749	169767772	3	-	27260156	NCIH1373	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.6934369241568127	[1185]	[1031,888,714,174]	-6	hSpCas9	negative selection	8016149
169769361	169769384	3	-	27260156	NCIH1373	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.37806505898049503	[137]	[95,111,159,26]	-4	hSpCas9	negative selection	8016150
169769364	169769387	3	+	27260156	NCIH1373	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.45094933186379244	[850]	[1219,624,482,142]	-4	hSpCas9	negative selection	8016151
169769480	169769503	3	+	27260156	PATU8902	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.3522677668218477	[328]	[887,288,523,652]	3	hSpCas9	negative selection	8073117
169769466	169769489	3	-	27260156	PATU8902	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.028725408488285975	[52]	[144,34,24,111]	0	hSpCas9	negative selection	8073118
169767619	169767642	3	+	27260156	PATU8902	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.26773513232508617	[905]	[1286,2373,1055,1466]	2	hSpCas9	negative selection	8073119
169767749	169767772	3	-	27260156	PATU8902	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.644145838532159	[1185]	[1622,925,798,912]	-6	hSpCas9	negative selection	8137400
169769361	169769384	3	-	27260156	PATU8902	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.4143119568847502	[137]	[113,259,43,189]	-4	hSpCas9	negative selection	8137401
169769364	169769387	3	+	27260156	PATU8902	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-1.0290113233690916	[850]	[968,377,260,815]	-7	hSpCas9	negative selection	8137402
169769480	169769503	3	+	27260156	PANC1	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.15004050169014427	[328]	[230,340,322,154]	-2	hSpCas9	negative selection	8194368
169769466	169769489	3	-	27260156	PANC1	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.014676289143323196	[52]	[75,33,37,33]	0	hSpCas9	negative selection	8194369
169767619	169767642	3	+	27260156	PANC1	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.17865804098953897	[905]	[726,637,764,610]	-3	hSpCas9	negative selection	8194370
169767749	169767772	3	-	27260156	PANC1	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.565520460699486	[1185]	[524,930,948,434]	-7	hSpCas9	negative selection	8258651
169769361	169769384	3	-	27260156	PANC1	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.808445710650473	[137]	[116,57,15,73]	-8	hSpCas9	negative selection	8258652
169769364	169769387	3	+	27260156	PANC1	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-1.0563736249935793	[850]	[354,423,242,385]	-8	hSpCas9	negative selection	8258653
169769480	169769503	3	+	27260156	PANC0813	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.28895017783611876	[328]	[292,314,360,294]	-4	hSpCas9	negative selection	8315619
169769466	169769489	3	-	27260156	PANC0813	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.16579950745849992	[52]	[44,61,132,38]	2	hSpCas9	negative selection	8315620
169767619	169767642	3	+	27260156	PANC0813	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.030277739728921227	[905]	[1329,1074,1037,765]	0	hSpCas9	negative selection	8315621
169767749	169767772	3	-	27260156	PANC0813	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.44003706506228213	[1185]	[1274,1006,907,942]	-6	hSpCas9	negative selection	8379902
169769361	169769384	3	-	27260156	PANC0813	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.1870928292374121	[137]	[191,127,149,105]	-3	hSpCas9	negative selection	8379903
169769364	169769387	3	+	27260156	PANC0813	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.5833443585662925	[850]	[726,834,564,551]	-7	hSpCas9	negative selection	8379904
169769480	169769503	3	+	27260156	RDES	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.06407417005905802	[328]	[337,272,447,399]	-1	hSpCas9	negative selection	8436870
169769466	169769489	3	-	27260156	RDES	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.37136634818279823	[52]	[59,72,97,88]	6	hSpCas9	negative selection	8436871
169767619	169767642	3	+	27260156	RDES	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.10612974281738519	[905]	[836,1195,1212,1289]	1	hSpCas9	negative selection	8436872
169767749	169767772	3	-	27260156	RDES	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.230200493416999	[1185]	[973,1181,1107,1427]	-4	hSpCas9	negative selection	8501153
169769361	169769384	3	-	27260156	RDES	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.6318543786866031	[137]	[73,83,154,103]	-8	hSpCas9	negative selection	8501154
169769364	169769387	3	+	27260156	RDES	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.48951878464677695	[850]	[634,560,736,890]	-7	hSpCas9	negative selection	8501155
169769480	169769503	3	+	27260156	PC3	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.2310756806734462	[328]	[223,203,336,373]	-5	hSpCas9	negative selection	8558121
169769466	169769489	3	-	27260156	PC3	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.3593079543218569	[52]	[38,65,143,57]	7	hSpCas9	negative selection	8558122
169767619	169767642	3	+	27260156	PC3	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.40056466537735924	[905]	[743,1117,1563,1588]	8	hSpCas9	negative selection	8558123
169767749	169767772	3	-	27260156	PC3	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.28294511270718026	[1185]	[744,799,1279,1186]	-6	hSpCas9	negative selection	8622404
169769361	169769384	3	-	27260156	PC3	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.6954123421464464	[137]	[47,31,113,172]	-9	hSpCas9	negative selection	8622405
169769364	169769387	3	+	27260156	PC3	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.646021907434592	[850]	[585,307,721,529]	-9	hSpCas9	negative selection	8622406
169769480	169769503	3	+	27260156	PATU8988T	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.30798683093484536	[328]	[421,533,273,355]	5	hSpCas9	negative selection	8679372
169769466	169769489	3	-	27260156	PATU8988T	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.845823270415377	[52]	[19,23,203,113]	9	hSpCas9	negative selection	8679373
169767619	169767642	3	+	27260156	PATU8988T	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.0662862228043376	[905]	[706,846,912,880]	-1	hSpCas9	negative selection	8679374
169767749	169767772	3	-	27260156	PATU8988T	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	0.020047583158256055	[1185]	[1137,1250,921,1364]	0	hSpCas9	negative selection	8743655
169769361	169769384	3	-	27260156	PATU8988T	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.14793826810865562	[137]	[101,219,65,101]	-3	hSpCas9	negative selection	8743656
169769364	169769387	3	+	27260156	PATU8988T	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.5848593253927542	[850]	[549,464,533,643]	-7	hSpCas9	negative selection	8743657
169769480	169769503	3	+	27260156	T47D	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.234947898131872	[328]	[309,294,382,315]	-5	hSpCas9	negative selection	8800623
169769466	169769489	3	-	27260156	T47D	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.256991885560216	[52]	[72,86,83,48]	5	hSpCas9	negative selection	8800624
169767619	169767642	3	+	27260156	T47D	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	-0.17732107384590534	[905]	[970,831,926,1014]	-4	hSpCas9	negative selection	8800625
169767749	169767772	3	-	27260156	T47D	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.27459932563008826	[1185]	[1165,1131,1100,1171]	-6	hSpCas9	negative selection	8864906
169769361	169769384	3	-	27260156	T47D	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.5013177334849446	[137]	[140,85,110,118]	-8	hSpCas9	negative selection	8864907
169769364	169769387	3	+	27260156	T47D	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.751203494583398	[850]	[601,557,613,583]	-9	hSpCas9	negative selection	8864908
169769480	169769503	3	+	27260156	SU8686	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.07091523832281837	[328]	[295,299,315,489]	1	hSpCas9	negative selection	8921874
169769466	169769489	3	-	27260156	SU8686	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.4055157097119402	[52]	[48,90,63,73]	6	hSpCas9	negative selection	8921875
169767619	169767642	3	+	27260156	SU8686	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.058587372792936576	[905]	[848,852,1021,1052]	1	hSpCas9	negative selection	8921876
169767749	169767772	3	-	27260156	SU8686	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.24645742564906703	[1185]	[849,864,1088,1226]	-4	hSpCas9	negative selection	8986157
169769361	169769384	3	-	27260156	SU8686	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.7539659879372604	[137]	[155,49,36,73]	-8	hSpCas9	negative selection	8986158
169769364	169769387	3	+	27260156	SU8686	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.5966072428170697	[850]	[500,432,752,570]	-7	hSpCas9	negative selection	8986159
169769480	169769503	3	+	27260156	SKES1	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.20171884163975584	[328]	[257,330,282,269]	-4	hSpCas9	negative selection	9043125
169769466	169769489	3	-	27260156	SKES1	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.12103285980822998	[52]	[63,41,71,50]	2	hSpCas9	negative selection	9043126
169767619	169767642	3	+	27260156	SKES1	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.37994795077098875	[905]	[1297,1387,1019,1045]	7	hSpCas9	negative selection	9043127
169767749	169767772	3	-	27260156	SKES1	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.1201722527001372	[1185]	[1270,1328,933,888]	-3	hSpCas9	negative selection	9107408
169769361	169769384	3	-	27260156	SKES1	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.21248903635560734	[137]	[144,133,82,117]	-5	hSpCas9	negative selection	9107409
169769364	169769387	3	+	27260156	SKES1	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.4707444773985573	[850]	[660,689,473,633]	-8	hSpCas9	negative selection	9107410
169769480	169769503	3	+	27260156	TOV112D	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.14553679505389783	[328]	[303,423,282,213]	-3	hSpCas9	negative selection	9164376
169769466	169769489	3	-	27260156	TOV112D	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.6934897720847566	[52]	[159,79,56,51]	9	hSpCas9	negative selection	9164377
169767619	169767642	3	+	27260156	TOV112D	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.17468255260331633	[905]	[1287,1564,611,791]	3	hSpCas9	negative selection	9164378
169767749	169767772	3	-	27260156	TOV112D	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.27658185558705584	[1185]	[1263,1021,873,799]	-5	hSpCas9	negative selection	9228659
169769361	169769384	3	-	27260156	TOV112D	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.6700271292411362	[137]	[112,99,97,42]	-8	hSpCas9	negative selection	9228660
169769364	169769387	3	+	27260156	TOV112D	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.3144892103599277	[850]	[673,1105,560,506]	-6	hSpCas9	negative selection	9228661
169769480	169769503	3	+	27260156	TC71	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	0.043180972466201395	[328]	[375,311,330,439]	1	hSpCas9	negative selection	9285627
169769466	169769489	3	-	27260156	TC71	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.5676554648816041	[52]	[75,78,82,99]	9	hSpCas9	negative selection	9285628
169767619	169767642	3	+	27260156	TC71	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.028920234498683528	[905]	[1082,930,1059,877]	0	hSpCas9	negative selection	9285629
169767749	169767772	3	-	27260156	TC71	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.029092246783246845	[1185]	[1371,1403,1076,1125]	0	hSpCas9	negative selection	9349910
169769361	169769384	3	-	27260156	TC71	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.6717277218800701	[137]	[104,140,64,58]	-9	hSpCas9	negative selection	9349911
169769364	169769387	3	+	27260156	TC71	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.4036481243022781	[850]	[733,768,630,620]	-8	hSpCas9	negative selection	9349912
169769480	169769503	3	+	27260156	TC32	viability	GAGCCGTTGTCGATCACCACCGG	ACTRT3	ENSG00000184378	-0.13382636240624013	[328]	[283,154,317,415]	-2	hSpCas9	negative selection	9406878
169769466	169769489	3	-	27260156	TC32	viability	CAACGGCTCGGGAATGATCAAGG	ACTRT3	ENSG00000184378	0.014299943853487651	[52]	[41,20,92,62]	0	hSpCas9	negative selection	9406879
169767619	169767642	3	+	27260156	TC32	viability	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.16178407520561067	[905]	[961,633,1445,914]	3	hSpCas9	negative selection	9406880
169767749	169767772	3	-	27260156	TC32	viability	TCCGTGTCATATGAACCTTGAGG	ACTRT3	ENSG00000184378	-0.09292507015023044	[1185]	[931,817,1476,1066]	-2	hSpCas9	negative selection	9471161
169769361	169769384	3	-	27260156	TC32	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.635320636820524	[137]	[105,21,64,157]	-8	hSpCas9	negative selection	9471162
169769364	169769387	3	+	27260156	TC32	viability	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.7416842005951949	[850]	[498,311,567,587]	-9	hSpCas9	negative selection	9471163
169767619	169767642	3	+	27869803	HPAFII	viability after 27 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.6442736535156486	[257]	[277,156,NaN]	5	hSpCas9	negative selection	9583441
169767620	169767643	3	+	27869803	HPAFII	viability after 27 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.16090307283437794	[332]	[366,52,NaN]	1	hSpCas9	negative selection	9583442
169767748	169767771	3	+	27869803	HPAFII	viability after 27 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-1.3925144826527043	[285]	[89,29,NaN]	-7	hSpCas9	negative selection	9583443
169769341	169769364	3	-	27869803	HPAFII	viability after 27 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.6409054057862354	[648]	[244,196,NaN]	-5	hSpCas9	negative selection	9583444
169769364	169769387	3	+	27869803	HPAFII	viability after 27 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-1.297496550989738	[325]	[72,66,NaN]	-7	hSpCas9	negative selection	9583445
169769463	169769486	3	-	27869803	HPAFII	viability after 27 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.7663164178986166	[559]	[123,213,NaN]	-5	hSpCas9	negative selection	9583446
169767619	169767642	3	+	27869803	HPAFII	viability after 15 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.4410540011741102	[257]	[389,367,NaN]	5	hSpCas9	negative selection	9665890
169767620	169767643	3	+	27869803	HPAFII	viability after 15 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.44843219998089096	[332]	[318,226,NaN]	-5	hSpCas9	negative selection	9665891
169767748	169767771	3	+	27869803	HPAFII	viability after 15 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.8922498173621197	[285]	[209,137,NaN]	-7	hSpCas9	negative selection	9665892
169769341	169769364	3	-	27869803	HPAFII	viability after 15 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.5773408989648364	[648]	[776,274,NaN]	-6	hSpCas9	negative selection	9665893
169769364	169769387	3	+	27869803	HPAFII	viability after 15 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.12280707708805672	[325]	[552,177,NaN]	-1	hSpCas9	negative selection	9665894
169769463	169769486	3	-	27869803	HPAFII	viability after 15 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.3347333580179708	[559]	[557,426,NaN]	-4	hSpCas9	negative selection	9665895
169767619	169767642	3	+	27869803	ASPC1	viability after 36 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.3342843647642692	[740]	[384,381,236]	3	hSpCas9	negative selection	9748339
169767620	169767643	3	+	27869803	ASPC1	viability after 36 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.7388656138050596	[1071]	[694,546,629]	7	hSpCas9	negative selection	9748340
169767748	169767771	3	+	27869803	ASPC1	viability after 36 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.14038745208568296	[795]	[241,282,231]	-1	hSpCas9	negative selection	9748341
169769341	169769364	3	-	27869803	ASPC1	viability after 36 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	0.3579231326732091	[1459]	[308,774,790]	3	hSpCas9	negative selection	9748342
169769364	169769387	3	+	27869803	ASPC1	viability after 36 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-0.2437541314844992	[1180]	[467,58,489]	-3	hSpCas9	negative selection	9748343
169769463	169769486	3	-	27869803	ASPC1	viability after 36 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.22690886910232966	[1297]	[333,500,329]	-2	hSpCas9	negative selection	9748344
169767619	169767642	3	+	27869803	PATU8988S	viability after 35 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.3044122039158867	[607]	[256,347,NaN]	3	hSpCas9	negative selection	9830788
169767620	169767643	3	+	27869803	PATU8988S	viability after 35 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.22801261106243575	[982]	[546,379,NaN]	2	hSpCas9	negative selection	9830789
169767748	169767771	3	+	27869803	PATU8988S	viability after 35 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	0.5625556749075666	[613]	[240,489,NaN]	6	hSpCas9	negative selection	9830790
169769341	169769364	3	-	27869803	PATU8988S	viability after 35 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.019274356795035308	[1342]	[627,438,NaN]	0	hSpCas9	negative selection	9830791
169769364	169769387	3	+	27869803	PATU8988S	viability after 35 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	0.25524589955183885	[943]	[575,330,NaN]	3	hSpCas9	negative selection	9830792
169769463	169769486	3	-	27869803	PATU8988S	viability after 35 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.139389851987208	[970]	[316,544,NaN]	1	hSpCas9	negative selection	9830793
169767619	169767642	3	+	27869803	PATU8988S	viability after 31 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.2531710161209487	[607]	[196,405,NaN]	3	hSpCas9	negative selection	9913237
169767620	169767643	3	+	27869803	PATU8988S	viability after 31 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.312592846436459	[982]	[466,511,NaN]	4	hSpCas9	negative selection	9913238
169767748	169767771	3	+	27869803	PATU8988S	viability after 31 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	0.5242128339393254	[613]	[253,476,NaN]	6	hSpCas9	negative selection	9913239
169769341	169769364	3	-	27869803	PATU8988S	viability after 31 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.13514559912528812	[1342]	[418,574,NaN]	-1	hSpCas9	negative selection	9913240
169769364	169769387	3	+	27869803	PATU8988S	viability after 31 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	0.36314016979047425	[943]	[444,533,NaN]	4	hSpCas9	negative selection	9913241
169769463	169769486	3	-	27869803	PATU8988S	viability after 31 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.15218811930251064	[970]	[237,488,NaN]	-2	hSpCas9	negative selection	9913242
169767619	169767642	3	+	27869803	HPAFII	viability after 35 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.4599556211007008	[257]	[197,158,NaN]	3	hSpCas9	negative selection	9995686
169767620	169767643	3	+	27869803	HPAFII	viability after 35 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	0.38142365629827585	[332]	[355,65,NaN]	2	hSpCas9	negative selection	9995687
169767748	169767771	3	+	27869803	HPAFII	viability after 35 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.4740569924541781	[285]	[107,99,NaN]	-3	hSpCas9	negative selection	9995688
169769341	169769364	3	-	27869803	HPAFII	viability after 35 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.7287299620073723	[648]	[249,139,NaN]	-4	hSpCas9	negative selection	9995689
169769364	169769387	3	+	27869803	HPAFII	viability after 35 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-1.7993673690599725	[325]	[53,39,NaN]	-7	hSpCas9	negative selection	9995690
169769463	169769486	3	-	27869803	HPAFII	viability after 35 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-1.3850389613207836	[559]	[21,205,NaN]	-6	hSpCas9	negative selection	9995691
169767619	169767642	3	+	27869803	HPAFII	viability after 31 days	ACTAACCGCTTGTCTAAACCAGG	ACTRT3	ENSG00000184378	0.6309242953834343	[257]	[217,230,NaN]	4	hSpCas9	negative selection	10078135
169767620	169767643	3	+	27869803	HPAFII	viability after 31 days	CTAACCGCTTGTCTAAACCAGGG	ACTRT3	ENSG00000184378	-0.055127646146251874	[332]	[299,48,NaN]	0	hSpCas9	negative selection	10078136
169767748	169767771	3	+	27869803	HPAFII	viability after 31 days	GCCTCAAGGTTCATATGACACGG	ACTRT3	ENSG00000184378	-0.7428263323505481	[285]	[93,97,NaN]	-5	hSpCas9	negative selection	10078137
169769341	169769364	3	-	27869803	HPAFII	viability after 31 days	TGGGCGACCAAGCTCAGGACTGG	ACTRT3	ENSG00000184378	-0.9794402575429945	[648]	[200,166,NaN]	-6	hSpCas9	negative selection	10078138
169769364	169769387	3	+	27869803	HPAFII	viability after 31 days	CGCAGAGTTCTAGCCCGCCCTGG	ACTRT3	ENSG00000184378	-1.6421765326082514	[325]	[49,67,NaN]	-7	hSpCas9	negative selection	10078139
169769463	169769486	3	-	27869803	HPAFII	viability after 31 days	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-1.0540307847937427	[559]	[58,251,NaN]	-6	hSpCas9	negative selection	10078140
169769496	169769519	3	-	28162770	P31FUJ	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.4331028848113905	[386]	[613]	5	hSpCas9	negative selection	10106594
169767788	169767811	3	+	28162770	P31FUJ	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	0.7178700832220533	[118]	[229]	7	hSpCas9	negative selection	10106595
169769361	169769384	3	-	28162770	P31FUJ	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.6364111880502672	[74]	[136]	7	hSpCas9	negative selection	10106596
169769338	169769361	3	-	28162770	P31FUJ	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.7495932024939553	[92]	[64]	-5	hSpCas9	negative selection	10106597
169769478	169769501	3	-	28162770	P31FUJ	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	0.05477438568220694	[67]	[82]	0	hSpCas9	negative selection	10106598
169769463	169769486	3	-	28162770	P31FUJ	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.12768549860016448	[171]	[184]	-1	hSpCas9	negative selection	10106599
169769420	169769443	3	+	28162770	P31FUJ	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.22726904847896895	[204]	[281]	2	hSpCas9	negative selection	10106600
169769403	169769426	3	-	28162770	P31FUJ	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	0.5921110890275302	[314]	[557]	6	hSpCas9	negative selection	10106601
169767964	169767987	3	-	28162770	P31FUJ	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.29272738278761956	[445]	[641]	3	hSpCas9	negative selection	10106602
169767878	169767901	3	-	28162770	P31FUJ	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	0.9536109198165028	[144]	[329]	9	hSpCas9	negative selection	10106603
169769496	169769519	3	-	28162770	TF1	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[192]	1	hSpCas9	negative selection	10275960
169767788	169767811	3	+	28162770	TF1	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10275961
169769361	169769384	3	-	28162770	TF1	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10275962
169769338	169769361	3	-	28162770	TF1	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10275963
169769478	169769501	3	-	28162770	TF1	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10275964
169769463	169769486	3	-	28162770	TF1	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10275965
169769420	169769443	3	+	28162770	TF1	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10275966
169769403	169769426	3	-	28162770	TF1	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10275967
169767964	169767987	3	-	28162770	TF1	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[228]	1	hSpCas9	negative selection	10275968
169767878	169767901	3	-	28162770	TF1	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	NaN	[NaN]	[87]	1	hSpCas9	negative selection	10275969
169769496	169769519	3	-	28162770	SKM1	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.4390441547183348	[120]	[289]	4	hSpCas9	negative selection	10445326
169767788	169767811	3	+	28162770	SKM1	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	-0.17563865263670597	[22]	[35]	-1	hSpCas9	negative selection	10445327
169769361	169769384	3	-	28162770	SKM1	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.2694606749932268	[29]	[43]	-2	hSpCas9	negative selection	10445328
169769338	169769361	3	-	28162770	SKM1	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.6751603096927343	[27]	[30]	-5	hSpCas9	negative selection	10445329
169769478	169769501	3	-	28162770	SKM1	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	-0.014646775964401337	[19]	[34]	0	hSpCas9	negative selection	10445330
169769463	169769486	3	-	28162770	SKM1	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	1.1779983019779945	[42]	[171]	9	hSpCas9	negative selection	10445331
169769420	169769443	3	+	28162770	SKM1	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.2119456339013322	[41]	[85]	2	hSpCas9	negative selection	10445332
169769403	169769426	3	-	28162770	SKM1	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	1.1523116583143451	[84]	[333]	9	hSpCas9	negative selection	10445333
169767964	169767987	3	-	28162770	SKM1	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.36242287311542193	[76]	[174]	3	hSpCas9	negative selection	10445334
169767878	169767901	3	-	28162770	SKM1	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	0.5086436139664657	[32]	[82]	5	hSpCas9	negative selection	10445335
169769496	169769519	3	-	28162770	SKM1	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.4390441547183348	[120]	[289]	4	hSpCas9	negative selection	10614692
169767788	169767811	3	+	28162770	SKM1	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	-0.17563865263670597	[22]	[35]	-1	hSpCas9	negative selection	10614693
169769361	169769384	3	-	28162770	SKM1	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.2694606749932268	[29]	[43]	-2	hSpCas9	negative selection	10614694
169769338	169769361	3	-	28162770	SKM1	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.6751603096927343	[27]	[30]	-5	hSpCas9	negative selection	10614695
169769478	169769501	3	-	28162770	SKM1	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	-0.014646775964401337	[19]	[34]	0	hSpCas9	negative selection	10614696
169769463	169769486	3	-	28162770	SKM1	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	1.1779983019779945	[42]	[171]	9	hSpCas9	negative selection	10614697
169769420	169769443	3	+	28162770	SKM1	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.2119456339013322	[41]	[85]	2	hSpCas9	negative selection	10614698
169769403	169769426	3	-	28162770	SKM1	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	1.1523116583143451	[84]	[333]	9	hSpCas9	negative selection	10614699
169767964	169767987	3	-	28162770	SKM1	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.36242287311542193	[76]	[174]	3	hSpCas9	negative selection	10614700
169767878	169767901	3	-	28162770	SKM1	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	0.5086436139664657	[32]	[82]	5	hSpCas9	negative selection	10614701
169769496	169769519	3	-	28162770	PL21	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	-0.2064007081129836	[394]	[148]	-1	hSpCas9	negative selection	10784058
169767788	169767811	3	+	28162770	PL21	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	0.5259097756710767	[74]	[46]	4	hSpCas9	negative selection	10784059
169769361	169769384	3	-	28162770	PL21	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.513556200354039	[81]	[24]	-4	hSpCas9	negative selection	10784060
169769338	169769361	3	-	28162770	PL21	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.3770173765733995	[91]	[51]	3	hSpCas9	negative selection	10784061
169769478	169769501	3	-	28162770	PL21	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	-2.0049748154152924	[82]	[8]	-8	hSpCas9	negative selection	10784062
169769463	169769486	3	-	28162770	PL21	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.9005793326304122	[175]	[142]	7	hSpCas9	negative selection	10784063
169769420	169769443	3	+	28162770	PL21	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	1.0914333550468203	[123]	[114]	8	hSpCas9	negative selection	10784064
169769403	169769426	3	-	28162770	PL21	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	0.19495937538363983	[278]	[138]	1	hSpCas9	negative selection	10784065
169767964	169767987	3	-	28162770	PL21	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.2346279908746109	[247]	[126]	2	hSpCas9	negative selection	10784066
169767878	169767901	3	-	28162770	PL21	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	-0.15831435642315617	[99]	[38]	-1	hSpCas9	negative selection	10784067
169769496	169769519	3	-	28162770	P31FUJ	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.4331028848113905	[386]	[613]	5	hSpCas9	negative selection	10953424
169767788	169767811	3	+	28162770	P31FUJ	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	0.7178700832220533	[118]	[229]	7	hSpCas9	negative selection	10953425
169769361	169769384	3	-	28162770	P31FUJ	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.6364111880502672	[74]	[136]	7	hSpCas9	negative selection	10953426
169769338	169769361	3	-	28162770	P31FUJ	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.7495932024939553	[92]	[64]	-5	hSpCas9	negative selection	10953427
169769478	169769501	3	-	28162770	P31FUJ	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	0.05477438568220694	[67]	[82]	0	hSpCas9	negative selection	10953428
169769463	169769486	3	-	28162770	P31FUJ	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.12768549860016448	[171]	[184]	-1	hSpCas9	negative selection	10953429
169769420	169769443	3	+	28162770	P31FUJ	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.22726904847896895	[204]	[281]	2	hSpCas9	negative selection	10953430
169769403	169769426	3	-	28162770	P31FUJ	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	0.5921110890275302	[314]	[557]	6	hSpCas9	negative selection	10953431
169767964	169767987	3	-	28162770	P31FUJ	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.29272738278761956	[445]	[641]	3	hSpCas9	negative selection	10953432
169767878	169767901	3	-	28162770	P31FUJ	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	0.9536109198165028	[144]	[329]	9	hSpCas9	negative selection	10953433
169769496	169769519	3	-	28162770	OCIAML5	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.547464342147338	[151]	[400]	5	hSpCas9	negative selection	11122790
169767788	169767811	3	+	28162770	OCIAML5	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	-0.15462934088442815	[73]	[119]	-1	hSpCas9	negative selection	11122791
169769361	169769384	3	-	28162770	OCIAML5	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.7402754602227567	[64]	[195]	6	hSpCas9	negative selection	11122792
169769338	169769361	3	-	28162770	OCIAML5	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.994085575736425	[63]	[57]	-6	hSpCas9	negative selection	11122793
169769478	169769501	3	-	28162770	OCIAML5	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	0.7656858649748286	[28]	[88]	6	hSpCas9	negative selection	11122794
169769463	169769486	3	-	28162770	OCIAML5	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.692818490481824	[72]	[212]	6	hSpCas9	negative selection	11122795
169769420	169769443	3	+	28162770	OCIAML5	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.27878090859562465	[78]	[172]	2	hSpCas9	negative selection	11122796
169769403	169769426	3	-	28162770	OCIAML5	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	-0.12336859268139144	[279]	[463]	-1	hSpCas9	negative selection	11122797
169767964	169767987	3	-	28162770	OCIAML5	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.9792672141280468	[178]	[636]	8	hSpCas9	negative selection	11122798
169767878	169767901	3	-	28162770	OCIAML5	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	-0.008792074551450035	[67]	[121]	0	hSpCas9	negative selection	11122799
169769496	169769519	3	-	28162770	EOL1	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	-0.2991008057363389	[765]	[327]	-2	hSpCas9	negative selection	11292156
169767788	169767811	3	+	28162770	EOL1	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	-0.8898965752733892	[101]	[28]	-6	hSpCas9	negative selection	11292157
169769361	169769384	3	-	28162770	EOL1	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.18758217740432814	[149]	[89]	1	hSpCas9	negative selection	11292158
169769338	169769361	3	-	28162770	EOL1	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.5429134305589044	[184]	[141]	5	hSpCas9	negative selection	11292159
169769478	169769501	3	-	28162770	EOL1	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	0.7860279074891068	[141]	[128]	7	hSpCas9	negative selection	11292160
169769463	169769486	3	-	28162770	EOL1	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.2424739359004004	[360]	[224]	2	hSpCas9	negative selection	11292161
169769420	169769443	3	+	28162770	EOL1	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	1.3086912629035945	[176]	[230]	9	hSpCas9	negative selection	11292162
169769403	169769426	3	-	28162770	EOL1	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	-0.3211045560350229	[395]	[166]	-2	hSpCas9	negative selection	11292163
169767964	169767987	3	-	28162770	EOL1	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.6454751556449696	[397]	[327]	6	hSpCas9	negative selection	11292164
169767878	169767901	3	-	28162770	EOL1	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	0.09650045435982935	[157]	[88]	0	hSpCas9	negative selection	11292165
169769496	169769519	3	-	28162770	MOLM13	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.6251701737346682	[572]	[638]	5	hSpCas9	negative selection	11461522
169767788	169767811	3	+	28162770	MOLM13	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	0.2074996969663485	[108]	[90]	1	hSpCas9	negative selection	11461523
169769361	169769384	3	-	28162770	MOLM13	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.4134415975222022	[107]	[103]	3	hSpCas9	negative selection	11461524
169769338	169769361	3	-	28162770	MOLM13	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	1.6028189616306872	[152]	[335]	9	hSpCas9	negative selection	11461525
169769478	169769501	3	-	28162770	MOLM13	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	-0.6864387648467152	[137]	[61]	-4	hSpCas9	negative selection	11461526
169769463	169769486	3	-	28162770	MOLM13	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.6034769753437541	[273]	[300]	4	hSpCas9	negative selection	11461527
169769420	169769443	3	+	28162770	MOLM13	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.7116554536735937	[200]	[237]	5	hSpCas9	negative selection	11461528
169769403	169769426	3	-	28162770	MOLM13	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	0.42256539103508844	[387]	[375]	3	hSpCas9	negative selection	11461529
169767964	169767987	3	-	28162770	MOLM13	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.9082824551003168	[422]	[573]	7	hSpCas9	negative selection	11461530
169767878	169767901	3	-	28162770	MOLM13	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	-0.19878776896794687	[226]	[142]	-1	hSpCas9	negative selection	11461531
169769496	169769519	3	-	28162770	HEL	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.9191227914931703	[501]	[607]	7	hSpCas9	negative selection	11630888
169767788	169767811	3	+	28162770	HEL	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	-0.8861896338064714	[100]	[34]	-5	hSpCas9	negative selection	11630889
169769361	169769384	3	-	28162770	HEL	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	1.6982339445920607	[101]	[211]	9	hSpCas9	negative selection	11630890
169769338	169769361	3	-	28162770	HEL	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.5396453390362533	[115]	[107]	4	hSpCas9	negative selection	11630891
169769478	169769501	3	-	28162770	HEL	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	0.2676994006534321	[82]	[63]	2	hSpCas9	negative selection	11630892
169769463	169769486	3	-	28162770	HEL	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.7399809470057588	[205]	[78]	-5	hSpCas9	negative selection	11630893
169769420	169769443	3	+	28162770	HEL	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	-0.40972858789377864	[167]	[80]	-3	hSpCas9	negative selection	11630894
169769403	169769426	3	-	28162770	HEL	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	-0.07866050477638137	[337]	[204]	0	hSpCas9	negative selection	11630895
169767964	169767987	3	-	28162770	HEL	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.08222937500373972	[350]	[237]	0	hSpCas9	negative selection	11630896
169767878	169767901	3	-	28162770	HEL	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	-1.0318608812054757	[165]	[51]	-6	hSpCas9	negative selection	11630897
169769496	169769519	3	-	28162770	MV411	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.04248557738876624	[369]	[320]	0	hSpCas9	negative selection	11800254
169767788	169767811	3	+	28162770	MV411	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	0.8324000515039315	[65]	[98]	7	hSpCas9	negative selection	11800255
169769361	169769384	3	-	28162770	MV411	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	-0.07449054410458711	[84]	[67]	0	hSpCas9	negative selection	11800256
169769338	169769361	3	-	28162770	MV411	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	0.3186962339525973	[78]	[82]	3	hSpCas9	negative selection	11800257
169769478	169769501	3	-	28162770	MV411	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	0.8216736449108729	[89]	[133]	7	hSpCas9	negative selection	11800258
169769463	169769486	3	-	28162770	MV411	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.8093164383908902	[146]	[216]	7	hSpCas9	negative selection	11800259
169769420	169769443	3	+	28162770	MV411	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.0320485171840898	[136]	[117]	0	hSpCas9	negative selection	11800260
169769403	169769426	3	-	28162770	MV411	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	0.28449964500432035	[268]	[275]	2	hSpCas9	negative selection	11800261
169767964	169767987	3	-	28162770	MV411	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.07616612363294628	[267]	[237]	0	hSpCas9	negative selection	11800262
169767878	169767901	3	-	28162770	MV411	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	0.6925770818510382	[82]	[112]	6	hSpCas9	negative selection	11800263
169769496	169769519	3	-	28162770	MONOMAC1	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	-0.17026993749676833	[266]	[271]	-1	hSpCas9	negative selection	11969620
169767788	169767811	3	+	28162770	MONOMAC1	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	0.0458196768366097	[59]	[70]	0	hSpCas9	negative selection	11969621
169769361	169769384	3	-	28162770	MONOMAC1	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.7769679444075019	[55]	[109]	7	hSpCas9	negative selection	11969622
169769338	169769361	3	-	28162770	MONOMAC1	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-0.5063649051672825	[56]	[45]	-4	hSpCas9	negative selection	11969623
169769478	169769501	3	-	28162770	MONOMAC1	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	1.3128241984208837	[45]	[130]	9	hSpCas9	negative selection	11969624
169769463	169769486	3	-	28162770	MONOMAC1	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-1.2086248213347657	[124]	[61]	-7	hSpCas9	negative selection	11969625
169769420	169769443	3	+	28162770	MONOMAC1	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.1345846440316526	[88]	[111]	1	hSpCas9	negative selection	11969626
169769403	169769426	3	-	28162770	MONOMAC1	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	-0.4332711935496323	[191]	[162]	-4	hSpCas9	negative selection	11969627
169767964	169767987	3	-	28162770	MONOMAC1	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.7857880091323142	[168]	[333]	7	hSpCas9	negative selection	11969628
169767878	169767901	3	-	28162770	MONOMAC1	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	2.6133019334368717	[68]	[483]	9	hSpCas9	negative selection	11969629
169769496	169769519	3	-	28162770	OCIAML2	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	0.20934579033921552	[70]	[454]	2	hSpCas9	negative selection	12138986
169767788	169767811	3	+	28162770	OCIAML2	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	-0.5530919854341341	[17]	[67]	-4	hSpCas9	negative selection	12138987
169769361	169769384	3	-	28162770	OCIAML2	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	0.29692408875746806	[20]	[142]	3	hSpCas9	negative selection	12138988
169769338	169769361	3	-	28162770	OCIAML2	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-1.577545029158673	[20]	[38]	-7	hSpCas9	negative selection	12138989
169769478	169769501	3	-	28162770	OCIAML2	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	0.6168330160081781	[7]	[67]	6	hSpCas9	negative selection	12138990
169769463	169769486	3	-	28162770	OCIAML2	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	0.9070408215721977	[32]	[342]	8	hSpCas9	negative selection	12138991
169769420	169769443	3	+	28162770	OCIAML2	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	-0.5091039730567969	[18]	[73]	-4	hSpCas9	negative selection	12138992
169769403	169769426	3	-	28162770	OCIAML2	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	-0.9003141004854064	[65]	[195]	-6	hSpCas9	negative selection	12138993
169767964	169767987	3	-	28162770	OCIAML2	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.5630009526391191	[52]	[433]	5	hSpCas9	negative selection	12138994
169767878	169767901	3	-	28162770	OCIAML2	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	0.28739738445187457	[16]	[114]	2	hSpCas9	negative selection	12138995
169769496	169769519	3	-	28162770	OCIAML3	viability	GAACCACTGCCAGCTACCGGTGG	ACTRT3	ENSG00000184378	-0.29702590256703165	[104]	[257]	-2	hSpCas9	negative selection	12308352
169767788	169767811	3	+	28162770	OCIAML3	viability	GACAAGAAAAGAGCTGGTCATGG	ACTRT3	ENSG00000184378	-0.28366751971201265	[24]	[61]	-2	hSpCas9	negative selection	12308353
169769361	169769384	3	-	28162770	OCIAML3	viability	GGGCGGGCTAGAACTCTGCGTGG	ACTRT3	ENSG00000184378	1.8424323356869046	[22]	[248]	9	hSpCas9	negative selection	12308354
169769338	169769361	3	-	28162770	OCIAML3	viability	GCGACCAAGCTCAGGACTGGAGG	ACTRT3	ENSG00000184378	-1.1345760216868659	[23]	[32]	-7	hSpCas9	negative selection	12308355
169769478	169769501	3	-	28162770	OCIAML3	viability	GGTGGTGATCGACAACGGCTCGG	ACTRT3	ENSG00000184378	0.42034765265290674	[24]	[100]	4	hSpCas9	negative selection	12308356
169769463	169769486	3	-	28162770	OCIAML3	viability	CGGCTCGGGAATGATCAAGGCGG	ACTRT3	ENSG00000184378	-0.9298749261693992	[64]	[102]	-6	hSpCas9	negative selection	12308357
169769420	169769443	3	+	28162770	OCIAML3	viability	ATGTTCGGGTAGATAAACTGGGG	ACTRT3	ENSG00000184378	0.2348804432830823	[37]	[134]	2	hSpCas9	negative selection	12308358
169769403	169769426	3	-	28162770	OCIAML3	viability	GAACATTATCGGCCGCGCCAAGG	ACTRT3	ENSG00000184378	-0.41294208127665044	[85]	[194]	-3	hSpCas9	negative selection	12308359
169767964	169767987	3	-	28162770	OCIAML3	viability	ATGGTGCTAATGAAGAACCATGG	ACTRT3	ENSG00000184378	0.364835034919077	[79]	[310]	3	hSpCas9	negative selection	12308360
169767878	169767901	3	-	28162770	OCIAML3	viability	TGTGGCAATGAACTACGAAGAGG	ACTRT3	ENSG00000184378	-0.48153291106575047	[36]	[79]	-4	hSpCas9	negative selection	12308361