Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:130399
• Symbol:ACVR1C
• Description:activin A receptor type 1C

DataSource: http://genomecrispr.dkfz.de/#!/results/ACVR1C

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
157587327	157587350	2	-	26472758	Jiyoye	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.304899037118622	[248]	[151]	-2	hSpCas9	negative selection	2313
157541131	157541154	2	-	26472758	Jiyoye	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.1280741108300043	[306]	[252]	1	hSpCas9	negative selection	2314
157538585	157538608	2	-	26472758	Jiyoye	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	0.7482122993409402	[74]	[94]	5	hSpCas9	negative selection	2315
157541103	157541126	2	-	26472758	Jiyoye	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	1.5647166584923533	[12]	[28]	8	hSpCas9	negative selection	2316
157587316	157587339	2	-	26472758	Jiyoye	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	-0.23025453910941818	[69]	[44]	-2	hSpCas9	negative selection	2317
157544483	157544506	2	-	26472758	Jiyoye	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.4170231674622205	[72]	[146]	8	hSpCas9	negative selection	2318
157542773	157542796	2	-	26472758	Jiyoye	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.7791441588928311	[101]	[131]	5	hSpCas9	negative selection	2319
157541088	157541111	2	+	26472758	Jiyoye	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	-0.23398725798574804	[300]	[192]	-2	hSpCas9	negative selection	2320
157544503	157544526	2	+	26472758	Jiyoye	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.03336054495354268	[91]	[70]	0	hSpCas9	negative selection	2321
157587175	157587198	2	+	26472758	Jiyoye	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.11528611299989455	[403]	[329]	0	hSpCas9	negative selection	2322
157587327	157587350	2	-	26472758	KBM7	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.4077686359467586	[902,706]	[614,393]	4	hSpCas9	negative selection	193431
157541131	157541154	2	-	26472758	KBM7	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	-0.10618215377131168	[964,1404]	[501,554]	-1	hSpCas9	negative selection	193432
157538585	157538608	2	-	26472758	KBM7	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-0.04644057068541252	[257,205]	[143,69]	0	hSpCas9	negative selection	193433
157541103	157541126	2	-	26472758	KBM7	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-0.2318503760320878	[78,44]	[28,19]	-2	hSpCas9	negative selection	193434
157587316	157587339	2	-	26472758	KBM7	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.3871628907171891	[168,283]	[94,186]	4	hSpCas9	negative selection	193435
157544483	157544506	2	-	26472758	KBM7	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.1464143095051407	[500,292]	[627,203]	9	hSpCas9	negative selection	193436
157542773	157542796	2	-	26472758	KBM7	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	-0.21973042327657688	[784,825]	[352,304]	-2	hSpCas9	negative selection	193437
157541088	157541111	2	+	26472758	KBM7	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.012197008373619145	[952,1165]	[509,509]	0	hSpCas9	negative selection	193438
157544503	157544526	2	+	26472758	KBM7	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.4861073691554844	[406,249]	[228,196]	5	hSpCas9	negative selection	193439
157587175	157587198	2	+	26472758	KBM7	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.18602001617830122	[1412,1438]	[810,727]	2	hSpCas9	negative selection	193440
157587327	157587350	2	-	26472758	Raji	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.01052199612101068	[384]	[89]	0	hSpCas9	negative selection	384549
157541131	157541154	2	-	26472758	Raji	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	-0.34237202391465726	[742]	[135]	-3	hSpCas9	negative selection	384550
157538585	157538608	2	-	26472758	Raji	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-0.10072465995660085	[133]	[28]	-1	hSpCas9	negative selection	384551
157541103	157541126	2	-	26472758	Raji	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	1.1073835353735997	[7]	[3]	8	hSpCas9	negative selection	384552
157587316	157587339	2	-	26472758	Raji	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.7954395290588592	[71]	[28]	7	hSpCas9	negative selection	384553
157544483	157544506	2	-	26472758	Raji	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.0100863340186848	[183]	[85]	8	hSpCas9	negative selection	384554
157542773	157542796	2	-	26472758	Raji	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.49440665848284676	[311]	[101]	5	hSpCas9	negative selection	384555
157541088	157541111	2	+	26472758	Raji	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.8012804076479195	[407]	[164]	7	hSpCas9	negative selection	384556
157544503	157544526	2	+	26472758	Raji	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.7970434147614487	[123]	[49]	7	hSpCas9	negative selection	384557
157587175	157587198	2	+	26472758	Raji	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.22080959670795375	[757]	[204]	2	hSpCas9	negative selection	384558
157587327	157587350	2	-	26472758	K562	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.020613871064190104	[577]	[480]	0	hSpCas9	negative selection	575667
157541131	157541154	2	-	26472758	K562	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	-0.20947785525017026	[877]	[640]	-1	hSpCas9	negative selection	575668
157538585	157538608	2	-	26472758	K562	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	0.01634416018645335	[211]	[180]	0	hSpCas9	negative selection	575669
157541103	157541126	2	-	26472758	K562	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-1.2062426813431184	[40]	[14]	-6	hSpCas9	negative selection	575670
157587316	157587339	2	-	26472758	K562	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.6062395496773219	[213]	[274]	5	hSpCas9	negative selection	575671
157544483	157544506	2	-	26472758	K562	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.1915910393122324	[444]	[857]	8	hSpCas9	negative selection	575672
157542773	157542796	2	-	26472758	K562	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	-0.10484807581142574	[585]	[459]	0	hSpCas9	negative selection	575673
157541088	157541111	2	+	26472758	K562	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	-0.0013914995645853967	[765]	[645]	0	hSpCas9	negative selection	575674
157544503	157544526	2	+	26472758	K562	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	-0.10576762726242872	[231]	[181]	0	hSpCas9	negative selection	575675
157587175	157587198	2	+	26472758	K562	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.14247593868429598	[1113]	[1037]	1	hSpCas9	negative selection	575676
157541106	157541129	2	-	26627737	DLD1	viability	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	-0.27758318950129257	[225]	[66,34,69]	-3	hSpCas9	negative selection	808932
157542705	157542728	2	-	26627737	DLD1	viability	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.6077131034193816	[235]	[47,58,39]	-5	hSpCas9	negative selection	808933
157544502	157544525	2	-	26627737	DLD1	viability	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.16651460435112142	[730]	[137,380,255]	1	hSpCas9	negative selection	808934
157556224	157556247	2	-	26627737	DLD1	viability	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	0.5053117104806641	[883]	[365,582,256]	5	hSpCas9	negative selection	808935
157587186	157587209	2	-	26627737	DLD1	viability	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.1766117249238527	[623]	[226,282,162]	1	hSpCas9	negative selection	808936
157587327	157587350	2	-	26627737	DLD1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.5523978740166093	[885]	[114,207,236]	-5	hSpCas9	negative selection	808937
157541106	157541129	2	-	26627737	GBM cells	viability after 5 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.2628771895702602	[114]	[79,67]	4	hSpCas9	negative selection	891247
157542705	157542728	2	-	26627737	GBM cells	viability after 5 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.25736784579816196	[233]	[141,157]	4	hSpCas9	negative selection	891248
157544502	157544525	2	-	26627737	GBM cells	viability after 5 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.20557521311973764	[265]	[157,170]	3	hSpCas9	negative selection	891249
157556224	157556247	2	-	26627737	GBM cells	viability after 5 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.33475847131676534	[320]	[159,112]	-5	hSpCas9	negative selection	891250
157587186	157587209	2	-	26627737	GBM cells	viability after 5 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.4405848126955465	[326]	[283,191]	6	hSpCas9	negative selection	891251
157587327	157587350	2	-	26627737	GBM cells	viability after 5 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.06706601618181118	[460]	[180,290]	-1	hSpCas9	negative selection	891252
157541106	157541129	2	-	26627737	GBM cells	viability after 13 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.35920401845930194	[114]	[84,75]	4	hSpCas9	negative selection	973562
157542705	157542728	2	-	26627737	GBM cells	viability after 13 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.38120745369374254	[233]	[198,137]	5	hSpCas9	negative selection	973563
157544502	157544525	2	-	26627737	GBM cells	viability after 13 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.2511105005942982	[265]	[184,160]	3	hSpCas9	negative selection	973564
157556224	157556247	2	-	26627737	GBM cells	viability after 13 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	0.07206891704861046	[320]	[224,148]	0	hSpCas9	negative selection	973565
157587186	157587209	2	-	26627737	GBM cells	viability after 13 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.5078349622750423	[326]	[259,245]	6	hSpCas9	negative selection	973566
157587327	157587350	2	-	26627737	GBM cells	viability after 13 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.07243950667519228	[460]	[278,249]	0	hSpCas9	negative selection	973567
157541106	157541129	2	-	26627737	GBM cells	viability after 21 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.5374203792308195	[114]	[109,72]	5	hSpCas9	negative selection	1055877
157542705	157542728	2	-	26627737	GBM cells	viability after 21 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.3379949446252426	[233]	[167,153]	3	hSpCas9	negative selection	1055878
157544502	157544525	2	-	26627737	GBM cells	viability after 21 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.6549554168584806	[265]	[249,206]	6	hSpCas9	negative selection	1055879
157556224	157556247	2	-	26627737	GBM cells	viability after 21 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.7254009160200672	[320]	[105,104]	-6	hSpCas9	negative selection	1055880
157587186	157587209	2	-	26627737	GBM cells	viability after 21 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.5730584370297258	[326]	[280,248]	6	hSpCas9	negative selection	1055881
157587327	157587350	2	-	26627737	GBM cells	viability after 21 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.6539876230476158	[460]	[438,352]	6	hSpCas9	negative selection	1055882
157541106	157541129	2	-	26627737	RPE1	viability after 9 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	-0.01833824008750727	[756]	[109,393]	0	hSpCas9	negative selection	1138192
157542705	157542728	2	-	26627737	RPE1	viability after 9 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-1.0542701544504234	[1288]	[137,266]	-6	hSpCas9	negative selection	1138193
157544502	157544525	2	-	26627737	RPE1	viability after 9 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.1939113167499673	[1130]	[240,397]	-1	hSpCas9	negative selection	1138194
157556224	157556247	2	-	26627737	RPE1	viability after 9 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	0.008923606591079603	[912]	[339,219]	0	hSpCas9	negative selection	1138195
157587186	157587209	2	-	26627737	RPE1	viability after 9 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.37030116524409773	[994]	[109,409]	-3	hSpCas9	negative selection	1138196
157587327	157587350	2	-	26627737	RPE1	viability after 9 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.4572120954295844	[1132]	[191,343]	-3	hSpCas9	negative selection	1138197
157541106	157541129	2	-	26627737	RPE1	viability after 12 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	-0.583913054399223	[756]	[107,164]	-4	hSpCas9	negative selection	1220507
157542705	157542728	2	-	26627737	RPE1	viability after 12 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-1.0399320557663547	[1288]	[216,116]	-6	hSpCas9	negative selection	1220508
157544502	157544525	2	-	26627737	RPE1	viability after 12 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.33736863231520453	[1130]	[482,278]	2	hSpCas9	negative selection	1220509
157556224	157556247	2	-	26627737	RPE1	viability after 12 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.22254469428307605	[912]	[183,237]	-1	hSpCas9	negative selection	1220510
157587186	157587209	2	-	26627737	RPE1	viability after 12 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.33841476529916514	[994]	[191,231]	-2	hSpCas9	negative selection	1220511
157587327	157587350	2	-	26627737	RPE1	viability after 12 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.4865609344437924	[1132]	[242,189]	-3	hSpCas9	negative selection	1220512
157541106	157541129	2	-	26627737	RPE1	viability after 15 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	-0.22360062057106567	[756]	[104,258]	-1	hSpCas9	negative selection	1302822
157542705	157542728	2	-	26627737	RPE1	viability after 15 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-1.1211211339425526	[1288]	[131,201]	-6	hSpCas9	negative selection	1302823
157544502	157544525	2	-	26627737	RPE1	viability after 15 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.08764139085787248	[1130]	[453,229]	0	hSpCas9	negative selection	1302824
157556224	157556247	2	-	26627737	RPE1	viability after 15 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.4878658380453524	[912]	[202,165]	-3	hSpCas9	negative selection	1302825
157587186	157587209	2	-	26627737	RPE1	viability after 15 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.0023191898547665346	[994]	[145,412]	0	hSpCas9	negative selection	1302826
157587327	157587350	2	-	26627737	RPE1	viability after 15 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.15992474499313875	[1132]	[265,306]	-1	hSpCas9	negative selection	1302827
157541106	157541129	2	-	26627737	RPE1	viability after 18 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	-0.6103834077235226	[756]	[142,123]	-4	hSpCas9	negative selection	1385137
157542705	157542728	2	-	26627737	RPE1	viability after 18 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.9766955060583371	[1288]	[198,152]	-6	hSpCas9	negative selection	1385138
157544502	157544525	2	-	26627737	RPE1	viability after 18 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.12420484842296775	[1130]	[351,311]	0	hSpCas9	negative selection	1385139
157556224	157556247	2	-	26627737	RPE1	viability after 18 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.14344304729689322	[912]	[195,251]	-1	hSpCas9	negative selection	1385140
157587186	157587209	2	-	26627737	RPE1	viability after 18 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.19423452545145037	[994]	[196,424]	1	hSpCas9	negative selection	1385141
157587327	157587350	2	-	26627737	RPE1	viability after 18 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.5881686964952568	[1132]	[170,237]	-4	hSpCas9	negative selection	1385142
157541106	157541129	2	-	26627737	HeLa	viability after 8 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.1805113406062068	[300]	[164,165,119]	1	hSpCas9	negative selection	1467452
157542705	157542728	2	-	26627737	HeLa	viability after 8 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-1.3866926733267868	[352]	[131,25,35]	-8	hSpCas9	negative selection	1467453
157544502	157544525	2	-	26627737	HeLa	viability after 8 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.548719088284341	[677]	[494,283,522]	5	hSpCas9	negative selection	1467454
157556224	157556247	2	-	26627737	HeLa	viability after 8 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.18874796099215052	[483]	[302,116,161]	-2	hSpCas9	negative selection	1467455
157587186	157587209	2	-	26627737	HeLa	viability after 8 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.45209600869357497	[388]	[258,154,282]	4	hSpCas9	negative selection	1467456
157587327	157587350	2	-	26627737	HeLa	viability after 8 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.7473409198469512	[769]	[277,137,199]	-6	hSpCas9	negative selection	1467457
157541106	157541129	2	-	26627737	HeLa	viability after 12 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.19566750548124268	[300]	[127,160,135]	1	hSpCas9	negative selection	1549767
157542705	157542728	2	-	26627737	HeLa	viability after 12 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.4264284020852111	[352]	[155,89,82]	-4	hSpCas9	negative selection	1549768
157544502	157544525	2	-	26627737	HeLa	viability after 12 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.06679479820278067	[677]	[484,113,305]	0	hSpCas9	negative selection	1549769
157556224	157556247	2	-	26627737	HeLa	viability after 12 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.3761486621691771	[483]	[199,84,185]	-3	hSpCas9	negative selection	1549770
157587186	157587209	2	-	26627737	HeLa	viability after 12 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.4420184882901754	[388]	[166,205,281]	4	hSpCas9	negative selection	1549771
157587327	157587350	2	-	26627737	HeLa	viability after 12 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.5799941173301324	[769]	[279,189,172]	-5	hSpCas9	negative selection	1549772
157541106	157541129	2	-	26627737	HeLa	viability after 15 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.12478941656800474	[300]	[81,215,100]	1	hSpCas9	negative selection	1632082
157542705	157542728	2	-	26627737	HeLa	viability after 15 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.21140848252766414	[352]	[105,209,50]	-2	hSpCas9	negative selection	1632083
157544502	157544525	2	-	26627737	HeLa	viability after 15 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.31524158129221747	[677]	[404,153,480]	2	hSpCas9	negative selection	1632084
157556224	157556247	2	-	26627737	HeLa	viability after 15 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	0.20080515966890988	[483]	[191,198,293]	1	hSpCas9	negative selection	1632085
157587186	157587209	2	-	26627737	HeLa	viability after 15 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.5659379562564064	[388]	[187,243,274]	4	hSpCas9	negative selection	1632086
157587327	157587350	2	-	26627737	HeLa	viability after 15 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.21085834895580957	[769]	[304,176,334]	-2	hSpCas9	negative selection	1632087
157541106	157541129	2	-	26627737	HeLa	viability after 18 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.16905578124972068	[300]	[58,183,100]	1	hSpCas9	negative selection	1714397
157542705	157542728	2	-	26627737	HeLa	viability after 18 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.2284245398691867	[352]	[68,172,50]	-2	hSpCas9	negative selection	1714398
157544502	157544525	2	-	26627737	HeLa	viability after 18 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.3384759079311278	[677]	[282,126,480]	3	hSpCas9	negative selection	1714399
157556224	157556247	2	-	26627737	HeLa	viability after 18 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	0.2259745344853747	[483]	[129,172,293]	2	hSpCas9	negative selection	1714400
157587186	157587209	2	-	26627737	HeLa	viability after 18 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.5210410109623972	[388]	[112,200,274]	4	hSpCas9	negative selection	1714401
157587327	157587350	2	-	26627737	HeLa	viability after 18 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.19857032591259083	[769]	[211,142,334]	-2	hSpCas9	negative selection	1714402
157541106	157541129	2	-	26627737	HCT116	viability after 6 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	2.2735732211595745	[136]	[78,117]	9	hSpCas9	negative selection	1796712
157542705	157542728	2	-	26627737	HCT116	viability after 6 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.7271589139268151	[418]	[91,10]	-4	hSpCas9	negative selection	1796713
157544502	157544525	2	-	26627737	HCT116	viability after 6 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.17039433885623015	[693]	[7,145]	-1	hSpCas9	negative selection	1796714
157556224	157556247	2	-	26627737	HCT116	viability after 6 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-1.8464180528652387	[396]	[17,16]	-8	hSpCas9	negative selection	1796715
157587186	157587209	2	-	26627737	HCT116	viability after 6 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	1.1579441364568532	[472]	[85,209]	6	hSpCas9	negative selection	1796716
157587327	157587350	2	-	26627737	HCT116	viability after 6 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.587571666861843	[1055]	[201,59]	-3	hSpCas9	negative selection	1796717
157541106	157541129	2	-	26627737	HCT116	viability after 8 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.7360947893468377	[176]	[160,135,189]	7	hSpCas9	negative selection	1879027
157542705	157542728	2	-	26627737	HCT116	viability after 8 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.6701713651000156	[302]	[112,103,97]	-7	hSpCas9	negative selection	1879028
157544502	157544525	2	-	26627737	HCT116	viability after 8 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.03329380262924719	[561]	[253,352,299]	0	hSpCas9	negative selection	1879029
157556224	157556247	2	-	26627737	HCT116	viability after 8 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.7474438852891162	[468]	[210,111,139]	-7	hSpCas9	negative selection	1879030
157587186	157587209	2	-	26627737	HCT116	viability after 8 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.49732576995291516	[433]	[141,133,230]	-5	hSpCas9	negative selection	1879031
157587327	157587350	2	-	26627737	HCT116	viability after 8 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.5327446424134046	[287]	[226,256,204]	5	hSpCas9	negative selection	1879032
157541106	157541129	2	-	26627737	HCT116	viability after 9 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.3962461545168878	[136]	[41,52]	3	hSpCas9	negative selection	1961342
157542705	157542728	2	-	26627737	HCT116	viability after 9 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.4909549337711159	[418]	[30,256]	3	hSpCas9	negative selection	1961343
157544502	157544525	2	-	26627737	HCT116	viability after 9 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.5980317511897365	[693]	[208,336]	4	hSpCas9	negative selection	1961344
157556224	157556247	2	-	26627737	HCT116	viability after 9 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	1.4725066731262706	[396]	[282,302]	8	hSpCas9	negative selection	1961345
157587186	157587209	2	-	26627737	HCT116	viability after 9 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	1.2571385844413379	[472]	[612,55]	8	hSpCas9	negative selection	1961346
157587327	157587350	2	-	26627737	HCT116	viability after 9 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-1.2293761239847305	[1055]	[112,125]	-7	hSpCas9	negative selection	1961347
157541106	157541129	2	-	26627737	HCT116	viability after 12 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.20590461084726697	[176]	[93,105,122]	2	hSpCas9	negative selection	2043657
157542705	157542728	2	-	26627737	HCT116	viability after 12 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.4735282679456385	[302]	[89,105,149]	-5	hSpCas9	negative selection	2043658
157544502	157544525	2	-	26627737	HCT116	viability after 12 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.3626720688052052	[561]	[168,335,191]	-4	hSpCas9	negative selection	2043659
157556224	157556247	2	-	26627737	HCT116	viability after 12 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.4316416182724081	[468]	[204,171,168]	-5	hSpCas9	negative selection	2043660
157587186	157587209	2	-	26627737	HCT116	viability after 12 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.47065873073851183	[433]	[100,149,247]	-5	hSpCas9	negative selection	2043661
157587327	157587350	2	-	26627737	HCT116	viability after 12 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.6326172264103607	[287]	[169,290,249]	6	hSpCas9	negative selection	2043662
157541106	157541129	2	-	26627737	HCT116	viability after 15 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.23032562448666993	[176]	[130,94,132]	2	hSpCas9	negative selection	2125972
157542705	157542728	2	-	26627737	HCT116	viability after 15 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.027765898185656654	[302]	[180,205,145]	0	hSpCas9	negative selection	2125973
157544502	157544525	2	-	26627737	HCT116	viability after 15 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.17985201825375907	[561]	[198,416,228]	-2	hSpCas9	negative selection	2125974
157556224	157556247	2	-	26627737	HCT116	viability after 15 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.5147433197312796	[468]	[90,216,244]	-5	hSpCas9	negative selection	2125975
157587186	157587209	2	-	26627737	HCT116	viability after 15 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.06898653709453562	[433]	[125,232,338]	0	hSpCas9	negative selection	2125976
157587327	157587350	2	-	26627737	HCT116	viability after 15 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.705868646862251	[287]	[251,269,284]	6	hSpCas9	negative selection	2125977
157541106	157541129	2	-	26627737	HCT116	viability after 18 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.18522517478277034	[176]	[88,73,131]	1	hSpCas9	negative selection	2208287
157542705	157542728	2	-	26627737	HCT116	viability after 18 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.7363268806890185	[302]	[57,106,97]	-6	hSpCas9	negative selection	2208288
157544502	157544525	2	-	26627737	HCT116	viability after 18 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.1412626139128269	[561]	[152,447,118]	-1	hSpCas9	negative selection	2208289
157556224	157556247	2	-	26627737	HCT116	viability after 18 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.4252515049287746	[468]	[89,128,295]	-4	hSpCas9	negative selection	2208290
157587186	157587209	2	-	26627737	HCT116	viability after 18 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.40928821437204854	[433]	[123,205,139]	-4	hSpCas9	negative selection	2208291
157587327	157587350	2	-	26627737	HCT116	viability after 18 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	1.0569433563847301	[287]	[307,213,354]	7	hSpCas9	negative selection	2208292
157544502	157544525	2	-	24336569	HL60	viability	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.16099394376165738	[305]	[723]	1	hSpCas9	negative selection	2246543
157544516	157544539	2	-	24336569	HL60	viability	AGAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	0.424318308873025	[748]	[2126]	4	hSpCas9	negative selection	2246544
157544561	157544584	2	-	24336569	HL60	viability	GTATCTGAATATCATGAACAGGG	ACVR1C	ENSG00000123612	0.20126610654581722	[193]	[471]	2	hSpCas9	negative selection	2246545
157544583	157544606	2	-	24336569	HL60	viability	AACTTGGACTCAACTTTGGCTGG	ACVR1C	ENSG00000123612	0.16866432100796014	[654]	[1557]	1	hSpCas9	negative selection	2246546
157544599	157544622	2	-	24336569	HL60	viability	TCTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.03253267023640882	[224]	[486]	0	hSpCas9	negative selection	2246547
157587186	157587209	2	-	24336569	HL60	viability	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.04043683236884138	[675]	[1390]	0	hSpCas9	negative selection	2246548
157587270	157587293	2	+	24336569	HL60	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.7023916256998333	[335]	[1156]	6	hSpCas9	negative selection	2246549
157587275	157587298	2	+	24336569	HL60	viability	TTGAGCATTCAGTTCTGGAAGGG	ACVR1C	ENSG00000123612	-0.015374910171123801	[959]	[2009]	0	hSpCas9	negative selection	2246550
157587284	157587307	2	+	24336569	HL60	viability	CAGTTCTGGAAGGGAGACACAGG	ACVR1C	ENSG00000123612	-0.01919996091794718	[1008]	[2106]	0	hSpCas9	negative selection	2246551
157587327	157587350	2	-	24336569	HL60	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	1.0503611108785231	[323]	[1419]	7	hSpCas9	negative selection	2246552
157544502	157544525	2	-	24336569	KBM7	viability	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.6584405105722309	[258]	[1114]	6	hSpCas9	negative selection	2313720
157544516	157544539	2	-	24336569	KBM7	viability	AGAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	0.5394335494627867	[808]	[3206]	5	hSpCas9	negative selection	2313721
157544561	157544584	2	-	24336569	KBM7	viability	GTATCTGAATATCATGAACAGGG	ACVR1C	ENSG00000123612	1.1400976888693095	[176]	[1063]	8	hSpCas9	negative selection	2313722
157544583	157544606	2	-	24336569	KBM7	viability	AACTTGGACTCAACTTTGGCTGG	ACVR1C	ENSG00000123612	0.45693196296290484	[444]	[1665]	4	hSpCas9	negative selection	2313723
157544599	157544622	2	-	24336569	KBM7	viability	TCTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.5011020261661372	[185]	[717]	4	hSpCas9	negative selection	2313724
157587186	157587209	2	-	24336569	KBM7	viability	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	1.3173660932008326	[359]	[2446]	9	hSpCas9	negative selection	2313725
157587270	157587293	2	+	24336569	KBM7	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	1.2748868279222085	[259]	[1715]	9	hSpCas9	negative selection	2313726
157587275	157587298	2	+	24336569	KBM7	viability	TTGAGCATTCAGTTCTGGAAGGG	ACVR1C	ENSG00000123612	0.5128924392644802	[517]	[2015]	5	hSpCas9	negative selection	2313727
157587284	157587307	2	+	24336569	KBM7	viability	CAGTTCTGGAAGGGAGACACAGG	ACVR1C	ENSG00000123612	0.6523646521471762	[588]	[2524]	6	hSpCas9	negative selection	2313728
157587327	157587350	2	-	24336569	KBM7	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.9383498982673303	[290]	[1520]	7	hSpCas9	negative selection	2313729
157597605	157597628	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATCTAGTGGCAGCAGAAGCAGG	ACVR1C	ENSG00000123612	3.1989435229524776	[7,89]	[4,204]	8	dCas9-VP64	positive selection	2396809
157597653	157597676	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAAATGCTAATCCGGAGTGGAGG	ACVR1C	ENSG00000123612	5.1349018616677515	[38,6]	[2,371]	9	dCas9-VP64	positive selection	2396810
157597642	157597665	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTACAGAATGACCTCCACTCCGG	ACVR1C	ENSG00000123612	-1.8317341254537822	[290,317]	[24,10]	-8	dCas9-VP64	positive selection	2396811
157629000	157629023	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCTGGGCGATCTCACTGCCGGG	ACVR1C	ENSG00000123612	-0.026896450948700412	[285,1107]	[261,32]	0	dCas9-VP64	positive selection	2396812
157628982	157629005	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAAAGGCGGCCCTGTGCCCGG	ACVR1C	ENSG00000123612	0.5764352295871881	[217,72]	[54,37]	2	dCas9-VP64	positive selection	2396813
157556712	157556735	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGTGCGATCTGGG	ACVR1C	ENSG00000123612	4.070372888524917	[22,16]	[45,107]	9	dCas9-VP64	positive selection	2443436
157626009	157626032	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACACCACTGCACTCCAGCCTGG	ACVR1C	ENSG00000123612	-0.6897978744123147	[436,52]	[50,12]	-4	dCas9-VP64	positive selection	2457828
157615448	157615471	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAGCCTTGACCTCCCGAG	ACVR1C	ENSG00000123612	-0.13547020725059378	[412,709]	[41,189]	0	dCas9-VP64	positive selection	2474426
157597605	157597628	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATCTAGTGGCAGCAGAAGCAGG	ACVR1C	ENSG00000123612	0.5160864684016593	[134,71]	[54,42]	4	dCas9-VP64	positive selection	2492064
157597653	157597676	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAAATGCTAATCCGGAGTGGAGG	ACVR1C	ENSG00000123612	3.9855729774068456	[102,70]	[905,29]	9	dCas9-VP64	positive selection	2492065
157597642	157597665	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTACAGAATGACCTCCACTCCGG	ACVR1C	ENSG00000123612	0.39573910583347016	[31,159]	[23,54]	3	dCas9-VP64	positive selection	2492066
157629000	157629023	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCTGGGCGATCTCACTGCCGGG	ACVR1C	ENSG00000123612	0.06545873753650389	[108,248]	[49,69]	0	dCas9-VP64	positive selection	2492067
157628982	157629005	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAAAGGCGGCCCTGTGCCCGG	ACVR1C	ENSG00000123612	-0.3908146280294065	[108,52]	[27,12]	-4	dCas9-VP64	positive selection	2492068
157556712	157556735	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGTGCGATCTGGG	ACVR1C	ENSG00000123612	1.6841538162097147	[121,126]	[189,75]	8	dCas9-VP64	positive selection	2538691
157626009	157626032	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACACCACTGCACTCCAGCCTGG	ACVR1C	ENSG00000123612	0.2274396231328648	[285,212]	[141,51]	1	dCas9-VP64	positive selection	2553083
157615448	157615471	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAGCCTTGACCTCCCGAG	ACVR1C	ENSG00000123612	0.2584978845854493	[172,83]	[35,62]	2	dCas9-VP64	positive selection	2569681
157587171	157587194	2	+	27013184	SW480	treatment with recombinant TRAIL	AAGATAAACCCCTTACCTGTTGG	ACVR1C	ENSG00000123612	-0.34284954799008577	[202,264]	[88,63]	-1	hSpCas9	positive selection	2959063
157628564	157628587	2	+	27013184	SW480	treatment with recombinant TRAIL	CACCGTACCTGGCGAGAGCTCGG	ACVR1C	ENSG00000123612	-0.9976806056219534	[78,341]	[56,22]	-4	hSpCas9	positive selection	2959064
157587175	157587198	2	+	27013184	SW480	treatment with recombinant TRAIL	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	-0.21437868005506422	[135,301]	[22,157]	-1	hSpCas9	positive selection	2959065
157587353	157587376	2	+	27013184	SW480	treatment with recombinant TRAIL	ACATGCTCCTTCTGTTTGGCAGG	ACVR1C	ENSG00000123612	0.5212939280996285	[236,292]	[214,87]	2	hSpCas9	positive selection	2959066
157587399	157587422	2	+	27013184	SW480	treatment with recombinant TRAIL	AGACATACACACTTCAGTCCTGG	ACVR1C	ENSG00000123612	-3.4932070179243064	[48,55]	[1,1]	-9	hSpCas9	positive selection	2959067
157587410	157587433	2	+	27013184	SW480	treatment with recombinant TRAIL	CTTCAGTCCTGGAAAGAGTAAGG	ACVR1C	ENSG00000123612	-0.542708330794432	[113,261]	[61,41]	-2	hSpCas9	positive selection	2959068
157587179	157587202	2	-	27013184	SW480	treatment with recombinant TRAIL	TGCACCTTCCAACAGGTAAGGGG	ACVR1C	ENSG00000123612	0.13022679120150304	[91,137]	[28,87]	0	hSpCas9	positive selection	2959069
157587180	157587203	2	-	27013184	SW480	treatment with recombinant TRAIL	CTGCACCTTCCAACAGGTAAGGG	ACVR1C	ENSG00000123612	0.4966001642386586	[353,323]	[141,299]	2	hSpCas9	positive selection	2959070
157587181	157587204	2	-	27013184	SW480	treatment with recombinant TRAIL	ACTGCACCTTCCAACAGGTAAGG	ACVR1C	ENSG00000123612	1.5760646484093346	[434,591]	[491,878]	7	hSpCas9	positive selection	2959071
157587186	157587209	2	-	27013184	SW480	treatment with recombinant TRAIL	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-1.6287108957584804	[178,240]	[37,15]	-6	hSpCas9	positive selection	2959072
157587327	157587350	2	-	27013184	SW480	treatment with recombinant TRAIL	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-1.4186357859410874	[36,94]	[8,11]	-6	hSpCas9	positive selection	2959073
157587349	157587372	2	-	27013184	SW480	treatment with recombinant TRAIL	CCAAACAGAAGGAGCATGTTGGG	ACVR1C	ENSG00000123612	0.3126773683552424	[25,106]	[3,75]	1	hSpCas9	positive selection	2959074
157587350	157587373	2	-	27013184	SW480	treatment with recombinant TRAIL	GCCAAACAGAAGGAGCATGTTGG	ACVR1C	ENSG00000123612	-0.8269123279817844	[253,182]	[62,40]	-4	hSpCas9	positive selection	2959075
157587218	157587241	2	+	27013184	SW480	treatment with recombinant TRAIL	AAAATCTGTGAAGCAGCATTCGG	ACVR1C	ENSG00000123612	-0.3569208055994286	[564,688]	[182,246]	-1	hSpCas9	positive selection	2959076
157587360	157587383	2	-	27013184	SW480	treatment with recombinant TRAIL	AACTTCACCTGCCAAACAGAAGG	ACVR1C	ENSG00000123612	-0.6689021985861789	[129,234]	[58,32]	-3	hSpCas9	positive selection	2959077
157533962	157533985	2	+	27013184	SW480	treatment with recombinant TRAIL	TCTTAATACGAAGAGCAGTTAGG	ACVR1C	ENSG00000123612	-0.18226573619860886	[86,80]	[10,61]	-1	hSpCas9	positive selection	2959078
157533965	157533988	2	+	27013184	SW480	treatment with recombinant TRAIL	TAATACGAAGAGCAGTTAGGCGG	ACVR1C	ENSG00000123612	2.2735430502301597	[1,45]	[45,45]	8	hSpCas9	positive selection	2959079
157533966	157533989	2	+	27013184	SW480	treatment with recombinant TRAIL	AATACGAAGAGCAGTTAGGCGGG	ACVR1C	ENSG00000123612	-1.2555337450684443	[264,187]	[3,94]	-5	hSpCas9	positive selection	2959080
157587224	157587247	2	+	27013184	SW480	treatment with recombinant TRAIL	TGTGAAGCAGCATTCGGTTTTGG	ACVR1C	ENSG00000123612	-3.3025984133050175	[129,328]	[7,11]	-9	hSpCas9	positive selection	2959081
157587270	157587293	2	+	27013184	SW480	treatment with recombinant TRAIL	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.9307719448834892	[156,111]	[141,69]	4	hSpCas9	positive selection	2959082
157587274	157587297	2	+	27013184	SW480	treatment with recombinant TRAIL	CTTGAGCATTCAGTTCTGGAAGG	ACVR1C	ENSG00000123612	-2.8779612671126245	[75,126]	[4,6]	-8	hSpCas9	positive selection	2959083
157544463	157544486	2	-	27013184	SW480	treatment with recombinant TRAIL	TGGTCTGGCACACCTTCATATGG	ACVR1C	ENSG00000123612	-3.568206450200784	[185,291]	[10,4]	-9	hSpCas9	positive selection	2959084
157544516	157544539	2	-	27013184	SW480	treatment with recombinant TRAIL	AGAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	2.706741000547242	[7,28]	[39,62]	9	hSpCas9	positive selection	2959085
157544562	157544585	2	-	27013184	SW480	treatment with recombinant TRAIL	GGTATCTGAATATCATGAACAGG	ACVR1C	ENSG00000123612	0.8777507818014666	[368,303]	[323,190]	4	hSpCas9	positive selection	2959086
157544583	157544606	2	-	27013184	SW480	treatment with recombinant TRAIL	AACTTGGACTCAACTTTGGCTGG	ACVR1C	ENSG00000123612	1.456592210602488	[74,315]	[118,360]	6	hSpCas9	positive selection	2959087
157544587	157544610	2	-	27013184	SW480	treatment with recombinant TRAIL	ATGGAACTTGGACTCAACTTTGG	ACVR1C	ENSG00000123612	0.9249651201667575	[69,117]	[111,22]	4	hSpCas9	positive selection	2959088
157587275	157587298	2	+	27013184	SW480	treatment with recombinant TRAIL	TTGAGCATTCAGTTCTGGAAGGG	ACVR1C	ENSG00000123612	1.1081734976472664	[84,69]	[42,114]	5	hSpCas9	positive selection	2959089
157587284	157587307	2	+	27013184	SW480	treatment with recombinant TRAIL	CAGTTCTGGAAGGGAGACACAGG	ACVR1C	ENSG00000123612	-2.890056330494565	[277,309]	[2,36]	-8	hSpCas9	positive selection	2959090
157587311	157587334	2	+	27013184	SW480	treatment with recombinant TRAIL	GATCACCTGCTCTTTTCCATTGG	ACVR1C	ENSG00000123612	-1.3034338039130797	[1018,1176]	[224,141]	-6	hSpCas9	positive selection	2959091
157587349	157587372	2	+	27013184	SW480	treatment with recombinant TRAIL	CCCAACATGCTCCTTCTGTTTGG	ACVR1C	ENSG00000123612	1.4403726204590006	[456,591]	[631,571]	6	hSpCas9	positive selection	2959092
157587186	157587209	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.07184488105362019	[5,5]	[4,5]	1	hSpCas9	positive selection	2968793
157628597	157628620	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAGCAGCAGGAGAGCCTGGCGG	ACVR1C	ENSG00000123612	-1.0123956444217295	[1,1]	[0,0]	-9	hSpCas9	positive selection	2968794
157587327	157587350	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.5809458208050347	[3,3]	[1,1]	-7	hSpCas9	positive selection	2968795
157628611	157628634	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCTGCTCAGCGCTCCGCCAGG	ACVR1C	ENSG00000123612	0.3248918263374964	[1,1]	[0,2]	7	hSpCas9	positive selection	2968796
157587186	157587209	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.40061627706709335	[5,5]	[6,4]	7	hSpCas9	positive selection	3036651
157628597	157628620	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAGCAGCAGGAGAGCCTGGCGG	ACVR1C	ENSG00000123612	-0.6164345043713335	[1,1]	[0,0]	-8	hSpCas9	positive selection	3036652
157587327	157587350	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.6836437717259384	[3,3]	[2,0]	-8	hSpCas9	positive selection	3036653
157628611	157628634	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCTGCTCAGCGCTCCGCCAGG	ACVR1C	ENSG00000123612	-0.21951163063810997	[1,1]	[1,0]	-3	hSpCas9	positive selection	3036654
157587270	157587293		+	24336571	A375	resistance to PLX after 7 days	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.004579217127121282	[56,57]	[58,54]	0	hSpCas9	positive selection	3160437
157556205	157556228		-	24336571	A375	resistance to PLX after 7 days	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.03912666614588689	[48,45]	[47,43]	-1	hSpCas9	positive selection	3160448
157587186	157587209		-	24336571	A375	resistance to PLX after 7 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.17617689756048094	[36,38]	[41,42]	5	hSpCas9	positive selection	3160459
157556104	157556127		-	24336571	A375	resistance to PLX after 7 days	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.2693365686312639	[58,52]	[71,62]	7	hSpCas9	positive selection	3160470
157544483	157544506		-	24336571	A375	resistance to PLX after 7 days	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.42853218140003646	[6,7]	[10,9]	9	hSpCas9	positive selection	3160481
157556238	157556261		+	24336571	A375	resistance to PLX after 7 days	TACTGTCAGCATCGCAGCTATGG	ACVR1C	ENSG00000123612	0.03204142940263821	[14,20]	[17,17]	1	hSpCas9	positive selection	3160492
157544599	157544622		-	24336571	A375	resistance to PLX after 7 days	TCTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	-0.38281114396650434	[16,15]	[12,11]	-9	hSpCas9	positive selection	3160504
157550342	157550365		-	24336571	A375	resistance to PLX after 7 days	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.2595753899986679	[17,19]	[21,22]	7	hSpCas9	positive selection	3160515
157550378	157550401		-	24336571	A375	resistance to PLX after 7 days	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.07478836725682725	[26,22]	[22,23]	-2	hSpCas9	positive selection	3160526
157587270	157587293		+	24336571	A375	resistance to PLX after 14 days	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	-0.042205249478385554	[53,54]	[22,26]	0	hSpCas9	positive selection	3218230
157556205	157556228		-	24336571	A375	resistance to PLX after 14 days	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.002144197998974473	[56,43]	[17,27]	0	hSpCas9	positive selection	3218241
157587186	157587209		-	24336571	A375	resistance to PLX after 14 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.41275682202139663	[46,49]	[16,16]	-5	hSpCas9	positive selection	3218252
157556104	157556127		-	24336571	A375	resistance to PLX after 14 days	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.2786398270531363	[63,49]	[31,31]	3	hSpCas9	positive selection	3218263
157544483	157544506		-	24336571	A375	resistance to PLX after 14 days	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.7369295549938749	[6,5]	[4,4]	6	hSpCas9	positive selection	3218274
157556238	157556261		+	24336571	A375	resistance to PLX after 14 days	TACTGTCAGCATCGCAGCTATGG	ACVR1C	ENSG00000123612	0.5896090938148333	[13,15]	[10,9]	5	hSpCas9	positive selection	3218285
157544599	157544622		-	24336571	A375	resistance to PLX after 14 days	TCTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	-0.7658534947323872	[14,16]	[3,3]	-8	hSpCas9	positive selection	3218297
157550342	157550365		-	24336571	A375	resistance to PLX after 14 days	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.5207633224509297	[19,18]	[13,11]	5	hSpCas9	positive selection	3218308
157550378	157550401		-	24336571	A375	resistance to PLX after 14 days	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-1.2931522712821768	[33,36]	[5,5]	-9	hSpCas9	positive selection	3218319
157587270	157587293		+	24336571	A375	viability after 7 days	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.1200429316171201	[55]	[56,57]	1	hSpCas9	negative selection	3276023
157556205	157556228		-	24336571	A375	viability after 7 days	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.039582156791890366	[48]	[48,45]	0	hSpCas9	negative selection	3276034
157587186	157587209		-	24336571	A375	viability after 7 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.7035007405685296	[64]	[36,38]	-7	hSpCas9	negative selection	3276045
157556104	157556127		-	24336571	A375	viability after 7 days	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.5474192217507985	[39]	[58,52]	8	hSpCas9	negative selection	3276056
157544483	157544506		-	24336571	A375	viability after 7 days	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.17406062739128603	[6]	[6,7]	2	hSpCas9	negative selection	3276067
157556238	157556261		+	24336571	A375	viability after 7 days	TACTGTCAGCATCGCAGCTATGG	ACVR1C	ENSG00000123612	0.073621888786992	[17]	[14,20]	1	hSpCas9	negative selection	3276078
157544599	157544622		-	24336571	A375	viability after 7 days	TCTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.4752061890717026	[11]	[16,15]	7	hSpCas9	negative selection	3276090
157550342	157550365		-	24336571	A375	viability after 7 days	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.7063834500008168	[11]	[17,19]	9	hSpCas9	negative selection	3276101
157550378	157550401		-	24336571	A375	viability after 7 days	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.3870650110847853	[19]	[26,22]	6	hSpCas9	negative selection	3276112
157587270	157587293		+	24336571	A375	viability after 14 days	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.0710489316279519	[55]	[53,54]	0	hSpCas9	negative selection	3333816
157556205	157556228		-	24336571	A375	viability after 14 days	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.13793855905029306	[48]	[56,43]	1	hSpCas9	negative selection	3333827
157587186	157587209		-	24336571	A375	viability after 14 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.32414508330185665	[64]	[46,49]	-4	hSpCas9	negative selection	3333838
157556104	157556127		-	24336571	A375	viability after 14 days	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.5817450081641049	[39]	[63,49]	7	hSpCas9	negative selection	3333849
157544483	157544506		-	24336571	A375	viability after 14 days	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	-0.020081088185749496	[6]	[6,5]	0	hSpCas9	negative selection	3333860
157556238	157556261		+	24336571	A375	viability after 14 days	TACTGTCAGCATCGCAGCTATGG	ACVR1C	ENSG00000123612	-0.12126392824976445	[17]	[13,15]	-1	hSpCas9	negative selection	3333871
157544599	157544622		-	24336571	A375	viability after 14 days	TCTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.43667749868636985	[11]	[14,16]	5	hSpCas9	negative selection	3333883
157550342	157550365		-	24336571	A375	viability after 14 days	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.7768823292842814	[11]	[19,18]	8	hSpCas9	negative selection	3333894
157550378	157550401		-	24336571	A375	viability after 14 days	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.9062165091988221	[19]	[33,36]	9	hSpCas9	negative selection	3333905
157556104	157556127	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.05253133656077814	[150,143]	[0,0]	0	hSpCas9	positive selection	3335474
157550378	157550401	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-2.193251645956152	[728,669]	[0,0]	-9	hSpCas9	positive selection	3335475
157556205	157556228	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.2645436139645839	[150,216]	[0,0]	-2	hSpCas9	positive selection	3335476
157550342	157550365	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	-1.2264895658184216	[357,357]	[0,0]	-7	hSpCas9	positive selection	3354720
157587270	157587293	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	-0.6910410201388426	[246,246]	[0,0]	-5	hSpCas9	positive selection	3354721
157587327	157587350	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.7027373597681978	[93,93]	[0,0]	3	hSpCas9	positive selection	3354722
157587186	157587209	2	-	26780180	HT29	viability (Avana library 4 designs)	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.0105328470711931	[]	[]	0	hSpCas9	negative selection	3404743
157628596	157628619	2	+	26780180	HT29	viability (Avana library 4 designs)	CGAGCAGCAGGAGAGCCTGGCGG	ACVR1C	ENSG00000123612	3.63052777905759	[]	[]	9	hSpCas9	negative selection	3404744
157587327	157587350	2	-	26780180	HT29	viability (Avana library 4 designs)	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	1.18693835442993	[]	[]	4	hSpCas9	negative selection	3404745
157628611	157628634	2	-	26780180	HT29	viability (Avana library 4 designs)	GCTCTGCTCAGCGCTCCGCCAGG	ACVR1C	ENSG00000123612	2.23486493576345	[]	[]	7	hSpCas9	negative selection	3404746
157587327	157587350	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-3.9991357287639	[]	[]	-4	hSpCas9	negative selection	3476429
157587186	157587209	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-3.23391430046769	[]	[]	-4	hSpCas9	negative selection	3476430
157628596	157628619	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGAGCAGCAGGAGAGCCTGGCGG	ACVR1C	ENSG00000123612	-5.71204984771593	[]	[]	-6	hSpCas9	negative selection	3476431
157628611	157628634	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCTGCTCAGCGCTCCGCCAGG	ACVR1C	ENSG00000123612	6.87483181153167	[]	[]	9	hSpCas9	negative selection	3476432
157628590	157628613	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCTCCTGCTGCTCGCAGCGG	ACVR1C	ENSG00000123612	2.685615705681	[]	[]	4	hSpCas9	negative selection	3476433
157544561	157544584	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTATCTGAATATCATGAACAGGG	ACVR1C	ENSG00000123612	-10.7405079674778	[]	[]	-8	hSpCas9	negative selection	3476434
157587327	157587350	2	-	26780180	A375	viability (Avana lentiGuide)	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-2.01210039371984	[]	[]	-3	hSpCas9	negative selection	3585088
157587186	157587209	2	-	26780180	A375	viability (Avana lentiGuide)	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-1.36948552847136	[]	[]	-2	hSpCas9	negative selection	3585089
157628596	157628619	2	+	26780180	A375	viability (Avana lentiGuide)	CGAGCAGCAGGAGAGCCTGGCGG	ACVR1C	ENSG00000123612	16.0340887347499	[]	[]	8	hSpCas9	negative selection	3585090
157628611	157628634	2	-	26780180	A375	viability (Avana lentiGuide)	GCTCTGCTCAGCGCTCCGCCAGG	ACVR1C	ENSG00000123612	-2.08216526808081	[]	[]	-4	hSpCas9	negative selection	3585091
157628590	157628613	2	-	26780180	A375	viability (Avana lentiGuide)	GGCTCTCCTGCTGCTCGCAGCGG	ACVR1C	ENSG00000123612	-0.0213564776719426	[]	[]	0	hSpCas9	negative selection	3585092
157544561	157544584	2	-	26780180	A375	viability (Avana lentiGuide)	GTATCTGAATATCATGAACAGGG	ACVR1C	ENSG00000123612	-1.55512709830112	[]	[]	-3	hSpCas9	negative selection	3585093
157587327	157587350	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.2636080292385116	[5]	[4,3]	-4	hSpCas9	positive selection	3693747
157587186	157587209	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.26181664086196077	[6]	[5,4]	-4	hSpCas9	positive selection	3693748
157628596	157628619	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAGCAGCAGGAGAGCCTGGCGG	ACVR1C	ENSG00000123612	-0.5617983651405185	[3]	[1,2]	-7	hSpCas9	positive selection	3693749
157628611	157628634	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCTGCTCAGCGCTCCGCCAGG	ACVR1C	ENSG00000123612	0.3952615713800591	[3]	[4,5]	9	hSpCas9	positive selection	3693750
157628590	157628613	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCTCCTGCTGCTCGCAGCGG	ACVR1C	ENSG00000123612	0.3347504272978536	[4]	[6,5]	8	hSpCas9	positive selection	3693751
157544561	157544584	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATCTGAATATCATGAACAGGG	ACVR1C	ENSG00000123612	-0.4637614353952302	[8]	[5,5]	-6	hSpCas9	positive selection	3693752
157587327	157587350	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.009800991834573405	[4]	[2,5]	0	hSpCas9	positive selection	3802354
157587186	157587209	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.11537181064447755	[7]	[7,5]	2	hSpCas9	positive selection	3802355
157628596	157628619	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAGCAGCAGGAGAGCCTGGCGG	ACVR1C	ENSG00000123612	-1.5091510867635258	[4]	[0,1]	-9	hSpCas9	positive selection	3802356
157628611	157628634	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCTGCTCAGCGCTCCGCCAGG	ACVR1C	ENSG00000123612	0.14564205212368952	[3]	[2,4]	3	hSpCas9	positive selection	3802357
157628590	157628613	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCTCCTGCTGCTCGCAGCGG	ACVR1C	ENSG00000123612	0.19861703223107652	[5]	[5,5]	5	hSpCas9	positive selection	3802358
157544561	157544584	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATCTGAATATCATGAACAGGG	ACVR1C	ENSG00000123612	0.2533118402093166	[5]	[5,5]	6	hSpCas9	positive selection	3802359
157587270	157587293	2	+	26780180	A375	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.822339398233099	[]	[]	3	hSpCas9	negative selection	3910956
157556205	157556228	2	-	26780180	A375	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	1.01888767482015	[]	[]	5	hSpCas9	negative selection	3910957
157556104	157556127	2	-	26780180	A375	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	1.10155678258425	[]	[]	5	hSpCas9	negative selection	3910958
157587327	157587350	2	-	26780180	A375	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	1.20990936900151	[]	[]	6	hSpCas9	negative selection	3910959
157550342	157550365	2	-	26780180	A375	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	-0.0360919954747509	[]	[]	-1	hSpCas9	negative selection	3910960
157550378	157550401	2	-	26780180	A375	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.110424076059381	[]	[]	0	hSpCas9	negative selection	3910961
157587270	157587293	2	+	26780180	HT29	viability (GeCKOv2 library)	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.651069343058029	[]	[]	2	hSpCas9	negative selection	4018922
157556205	157556228	2	-	26780180	HT29	viability (GeCKOv2 library)	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	1.07366619949155	[]	[]	5	hSpCas9	negative selection	4018923
157556104	157556127	2	-	26780180	HT29	viability (GeCKOv2 library)	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.286356997659027	[]	[]	0	hSpCas9	negative selection	4018924
157587327	157587350	2	-	26780180	HT29	viability (GeCKOv2 library)	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	1.5437438380995	[]	[]	7	hSpCas9	negative selection	4018925
157550342	157550365	2	-	26780180	HT29	viability (GeCKOv2 library)	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.00351302124857424	[]	[]	0	hSpCas9	negative selection	4018926
157550378	157550401	2	-	26780180	HT29	viability (GeCKOv2 library)	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.0636989757438926	[]	[]	0	hSpCas9	negative selection	4018927
157587270	157587293	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.2053128782140673	[5]	[4,4]	5	hSpCas9	positive selection	4188519
157556205	157556228	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.3012861871895421	[5]	[4,4]	7	hSpCas9	positive selection	4188530
157587186	157587209	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.11082040260091136	[5]	[3,4]	3	hSpCas9	positive selection	4188541
157556104	157556127	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.29844168192047416	[5]	[4,4]	7	hSpCas9	positive selection	4188552
157544483	157544506	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	-0.032073344552191824	[3]	[1,2]	0	hSpCas9	positive selection	4188563
157556238	157556261	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACTGTCAGCATCGCAGCTATGG	ACVR1C	ENSG00000123612	0.29172333482440677	[3]	[2,3]	7	hSpCas9	positive selection	4188574
157544599	157544622	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	-0.20642134110529575	[3]	[1,1]	-5	hSpCas9	positive selection	4188587
157550342	157550365	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.39450353630196017	[3]	[2,3]	8	hSpCas9	positive selection	4188598
157550378	157550401	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.20447837784864645	[4]	[3,2]	5	hSpCas9	positive selection	4188609
157587270	157587293	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	1.3729989523086028	[4]	[5,6,3,6]	9	hSpCas9	positive selection	4252541
157556205	157556228	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	1.0577042619699424	[5]	[2,4,5,5]	7	hSpCas9	positive selection	4252552
157587186	157587209	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	1.023977994824913	[6]	[5,3,5,5]	7	hSpCas9	positive selection	4252563
157556104	157556127	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.826498405123538	[4]	[2,2,2,4]	5	hSpCas9	positive selection	4252574
157544483	157544506	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.9694046086771617	[2]	[1,0,0,3]	6	hSpCas9	positive selection	4252585
157556238	157556261	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACTGTCAGCATCGCAGCTATGG	ACVR1C	ENSG00000123612	0.788217740089785	[4]	[0,4,1,3]	5	hSpCas9	positive selection	4252596
157544599	157544622	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	-0.12331990881621857	[3]	[2,0,1,0]	-2	hSpCas9	positive selection	4252609
157550342	157550365	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.45265076489680833	[4]	[1,2,1,3]	3	hSpCas9	positive selection	4252620
157550378	157550401	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.37894044301868884	[4]	[5,3,4,0]	3	hSpCas9	positive selection	4252631
157556104	157556127	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.2679052536451283	[3]	[2,2]	5	hSpCas9	positive selection	4254395
157550378	157550401	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.5582280821894503	[5]	[5,6]	9	hSpCas9	positive selection	4254396
157556205	157556228	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.3110099572182045	[3]	[3,3]	6	hSpCas9	positive selection	4254397
157550342	157550365	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.49801281312770296	[3]	[3,3]	8	hSpCas9	positive selection	4318678
157587270	157587293	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	-0.009786061476973695	[3]	[2,2]	0	hSpCas9	positive selection	4318679
157587327	157587350	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.4225095961713351	[2]	[2,2]	8	hSpCas9	positive selection	4318680
157542773	157542795	2	-	27760321	OCIAML3	viability	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.7794403435649415	[343,292]	[469,368]	8	hSpCas9	negative selection	4375991
157544483	157544505	2	-	27760321	OCIAML3	viability	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	-0.0015452770047559017	[545,487]	[418,382]	0	hSpCas9	negative selection	4375992
157544516	157544538	2	-	27760321	OCIAML3	viability	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.14784998918942255	[631,510]	[280,557]	-1	hSpCas9	negative selection	4375993
157544599	157544621	2	-	27760321	OCIAML3	viability	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.39805053150954217	[48,44]	[70,18]	5	hSpCas9	negative selection	4375994
157587186	157587208	2	-	27760321	OCIAML3	viability	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.9733344532525824	[312,248]	[371,502]	9	hSpCas9	negative selection	4375995
157542773	157542795	2	-	27760321	OCIAML2	viability	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	-0.14723343712543568	[343,292]	[205,265]	-2	hSpCas9	negative selection	4459454
157544483	157544505	2	-	27760321	OCIAML2	viability	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.3378511122089562	[545,487]	[438,644]	4	hSpCas9	negative selection	4459455
157544516	157544538	2	-	27760321	OCIAML2	viability	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.79972470703838	[631,510]	[283,237]	-7	hSpCas9	negative selection	4459456
157544599	157544621	2	-	27760321	OCIAML2	viability	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	1.299645828692768	[48,44]	[71,121]	9	hSpCas9	negative selection	4459457
157587186	157587208	2	-	27760321	OCIAML2	viability	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.18025015605834532	[312,248]	[233,284]	2	hSpCas9	negative selection	4459458
157542773	157542795	2	-	27760321	MV411	viability	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	1.447050605111634	[343,292]	[531,629]	9	hSpCas9	negative selection	4542917
157544483	157544505	2	-	27760321	MV411	viability	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.7090034122609015	[545,487]	[271,984]	5	hSpCas9	negative selection	4542918
157544516	157544538	2	-	27760321	MV411	viability	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.28578554699065795	[631,510]	[172,509]	-2	hSpCas9	negative selection	4542919
157544599	157544621	2	-	27760321	MV411	viability	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	2.417198677143035	[48,44]	[199,113]	9	hSpCas9	negative selection	4542920
157587186	157587208	2	-	27760321	MV411	viability	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.7350540973902269	[312,248]	[273,355]	5	hSpCas9	negative selection	4542921
157542773	157542795	2	-	27760321	HL60	viability	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.4571438040644995	[343,292]	[355,355]	5	hSpCas9	negative selection	4626380
157544483	157544505	2	-	27760321	HL60	viability	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.6209687906182884	[545,487]	[586,713]	7	hSpCas9	negative selection	4626381
157544516	157544538	2	-	27760321	HL60	viability	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	0.6892523280109379	[631,510]	[721,776]	7	hSpCas9	negative selection	4626382
157544599	157544621	2	-	27760321	HL60	viability	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.027250709232791603	[48,44]	[42,34]	0	hSpCas9	negative selection	4626383
157587186	157587208	2	-	27760321	HL60	viability	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	1.252254513104214	[312,248]	[426,666]	9	hSpCas9	negative selection	4626384
157542773	157542795	2	-	27760321	HT1080	viability	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.36801042920730037	[292,228]	[169,94]	2	hSpCas9	negative selection	4709843
157544483	157544505	2	-	27760321	HT1080	viability	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.8908462041973446	[487,380]	[393,240]	5	hSpCas9	negative selection	4709844
157544516	157544538	2	-	27760321	HT1080	viability	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-1.0663018212191435	[510,398]	[129,38]	-4	hSpCas9	negative selection	4709845
157544599	157544621	2	-	27760321	HT1080	viability	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	1.989845841858277	[44,34]	[26,102]	9	hSpCas9	negative selection	4709846
157587186	157587208	2	-	27760321	HT1080	viability	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	2.0825422375301152	[248,194]	[356,393]	9	hSpCas9	negative selection	4709847
157542773	157542795	2	-	27760321	HT29	viability after 7 days	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.5169286005259204	[292,228]	[357,408,649]	7	hSpCas9	negative selection	4793306
157544483	157544505	2	-	27760321	HT29	viability after 7 days	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.4507070574422153	[487,380]	[1023,583,719]	7	hSpCas9	negative selection	4793307
157544516	157544538	2	-	27760321	HT29	viability after 7 days	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.9005519421576729	[510,398]	[314,313,310]	-8	hSpCas9	negative selection	4793308
157544599	157544621	2	-	27760321	HT29	viability after 7 days	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.22692027886508592	[44,34]	[52,52,72]	3	hSpCas9	negative selection	4793309
157587186	157587208	2	-	27760321	HT29	viability after 7 days	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.8199684281193801	[248,194]	[340,324,811]	9	hSpCas9	negative selection	4793310
157542773	157542795	2	-	27760321	HT29	viability after 25 days	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	-0.07206705804320784	[292,228]	[310,272,262]	0	hSpCas9	negative selection	4876769
157544483	157544505	2	-	27760321	HT29	viability after 25 days	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.4249909243601375	[487,380]	[662,731,596]	4	hSpCas9	negative selection	4876770
157544516	157544538	2	-	27760321	HT29	viability after 25 days	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.2920827594844526	[510,398]	[572,430,240]	-3	hSpCas9	negative selection	4876771
157544599	157544621	2	-	27760321	HT29	viability after 25 days	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.5534346519426028	[44,34]	[25,64,117]	6	hSpCas9	negative selection	4876772
157587186	157587208	2	-	27760321	HT29	viability after 25 days	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.6626791998316299	[248,194]	[379,336,498]	7	hSpCas9	negative selection	4876773
157542773	157542795	2	-	27760321	HT29	viability after 22 days	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.3110030106622762	[292,228]	[478,287,352]	3	hSpCas9	negative selection	4960232
157544483	157544505	2	-	27760321	HT29	viability after 22 days	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.48305282711340225	[487,380]	[649,716,740]	5	hSpCas9	negative selection	4960233
157544516	157544538	2	-	27760321	HT29	viability after 22 days	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.30894313719755623	[510,398]	[513,376,379]	-3	hSpCas9	negative selection	4960234
157544599	157544621	2	-	27760321	HT29	viability after 22 days	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	1.2177435621504993	[44,34]	[139,42,138]	9	hSpCas9	negative selection	4960235
157587186	157587208	2	-	27760321	HT29	viability after 22 days	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.646461414832591	[248,194]	[319,447,439]	7	hSpCas9	negative selection	4960236
157542773	157542795	2	-	27760321	HT29	viability after 19 days	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.3781800465040255	[292,228]	[622,141,421]	3	hSpCas9	negative selection	5043695
157544483	157544505	2	-	27760321	HT29	viability after 19 days	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.0732746554602246	[487,380]	[1146,1037,964]	9	hSpCas9	negative selection	5043696
157544516	157544538	2	-	27760321	HT29	viability after 19 days	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.7483472324949986	[510,398]	[426,193,319]	-5	hSpCas9	negative selection	5043697
157544599	157544621	2	-	27760321	HT29	viability after 19 days	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.5304618590537897	[44,34]	[103,28,68]	5	hSpCas9	negative selection	5043698
157587186	157587208	2	-	27760321	HT29	viability after 19 days	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.8041878903123292	[248,194]	[389,452,479]	8	hSpCas9	negative selection	5043699
157542773	157542795	2	-	27760321	HT29	viability after 16 days	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.8387381900852535	[292,228]	[585,553,431]	8	hSpCas9	negative selection	5127158
157544483	157544505	2	-	27760321	HT29	viability after 16 days	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.6140189388047652	[487,380]	[758,758,714]	7	hSpCas9	negative selection	5127159
157544516	157544538	2	-	27760321	HT29	viability after 16 days	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-1.0995022016268725	[510,398]	[327,245,146]	-7	hSpCas9	negative selection	5127160
157544599	157544621	2	-	27760321	HT29	viability after 16 days	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.42037630860794506	[44,34]	[13,70,89]	5	hSpCas9	negative selection	5127161
157587186	157587208	2	-	27760321	HT29	viability after 16 days	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.5182707473342538	[248,194]	[437,398,236]	6	hSpCas9	negative selection	5127162
157542773	157542795	2	-	27760321	HT29	viability after 13 days	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.7777264566275734	[292,228]	[764,548,258]	8	hSpCas9	negative selection	5210621
157544483	157544505	2	-	27760321	HT29	viability after 13 days	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.21940961582024698	[487,380]	[538,589,628]	2	hSpCas9	negative selection	5210622
157544516	157544538	2	-	27760321	HT29	viability after 13 days	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.8424772891630294	[510,398]	[182,399,299]	-7	hSpCas9	negative selection	5210623
157544599	157544621	2	-	27760321	HT29	viability after 13 days	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	0.20534412701416427	[44,34]	[49,65,44]	2	hSpCas9	negative selection	5210624
157587186	157587208	2	-	27760321	HT29	viability after 13 days	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.702656200169669	[248,194]	[556,411,295]	8	hSpCas9	negative selection	5210625
157542773	157542795	2	-	27760321	HT29	viability after 10 days	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.728761177612915	[292,228]	[598,429,586]	8	hSpCas9	negative selection	5294084
157544483	157544505	2	-	27760321	HT29	viability after 10 days	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.5336013551313564	[487,380]	[1148,606,598]	7	hSpCas9	negative selection	5294085
157544516	157544538	2	-	27760321	HT29	viability after 10 days	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.43386487271969276	[510,398]	[405,414,439]	-5	hSpCas9	negative selection	5294086
157544599	157544621	2	-	27760321	HT29	viability after 10 days	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	-0.011500059778938088	[44,34]	[5,36,103]	0	hSpCas9	negative selection	5294087
157587186	157587208	2	-	27760321	HT29	viability after 10 days	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.5728485820652426	[248,194]	[360,453,422]	7	hSpCas9	negative selection	5294088
157542773	157542795	2	-	27760321	MOLM13	viability	GCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.6380146398372322	[343,292]	[342,223]	4	hSpCas9	negative selection	5377547
157544483	157544505	2	-	27760321	MOLM13	viability	TGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.1063955682583744	[545,487]	[1175,159]	7	hSpCas9	negative selection	5377548
157544516	157544538	2	-	27760321	MOLM13	viability	GAAATATAGTGACCGTGGCTGG	ACVR1C	ENSG00000123612	-0.8340704192731243	[631,510]	[140,212]	-5	hSpCas9	negative selection	5377549
157544599	157544621	2	-	27760321	MOLM13	viability	CTTGTTAGATAATGGAACTTGG	ACVR1C	ENSG00000123612	-0.25718676863295986	[48,44]	[12,29]	-2	hSpCas9	negative selection	5377550
157587186	157587208	2	-	27760321	MOLM13	viability	TAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.23434404170237616	[312,248]	[287,97]	1	hSpCas9	negative selection	5377551
157628456	157628479	2	-	27661255	K562	viability	GAGCAAACTGACCTTCGGGGCGG	ACVR1C	ENSG00000123612	-0.15367595390829303	[534,592]	[481,337]	-5	dCas9-KRAB	negative selection	5460817
157556104	157556127	2	-	27260156	BXPC3	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.4246778363647749	[504]	[557,639,674,1014]	8	hSpCas9	negative selection	5526855
157550378	157550401	2	-	27260156	BXPC3	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.056320198572720415	[2539]	[2616,2644,2871,2938]	1	hSpCas9	negative selection	5526856
157556205	157556228	2	-	27260156	BXPC3	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.04550447874844321	[803]	[736,735,902,901]	-1	hSpCas9	negative selection	5526857
157550342	157550365	2	-	27260156	BXPC3	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.245948465580064	[669]	[796,871,669,996]	5	hSpCas9	negative selection	5591138
157587270	157587293	2	+	27260156	BXPC3	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.2211086753568487	[623]	[829,673,812,711]	5	hSpCas9	negative selection	5591139
157587327	157587350	2	-	27260156	BXPC3	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.20510332646858453	[284]	[218,244,235,347]	-5	hSpCas9	negative selection	5591140
157556104	157556127	2	-	27260156	A673	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.2303635386086908	[504]	[732,709,745,653]	5	hSpCas9	negative selection	5648106
157550378	157550401	2	-	27260156	A673	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.08273621891282712	[2539]	[3425,3206,3054,3250]	2	hSpCas9	negative selection	5648107
157556205	157556228	2	-	27260156	A673	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.04029730118653807	[803]	[1074,940,897,1070]	0	hSpCas9	negative selection	5648108
157550342	157550365	2	-	27260156	A673	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.2623183698408136	[669]	[1048,905,1037,869]	6	hSpCas9	negative selection	5712389
157587270	157587293	2	+	27260156	A673	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.10528183213326608	[623]	[882,719,798,832]	2	hSpCas9	negative selection	5712390
157587327	157587350	2	-	27260156	A673	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.2799874345026755	[284]	[296,344,270,209]	-6	hSpCas9	negative selection	5712391
157556104	157556127	2	-	27260156	A375	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.5077263409273026	[504]	[1036,721,872,718]	7	hSpCas9	negative selection	5769357
157550378	157550401	2	-	27260156	A375	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.184675009295022	[2539]	[3680,4310,3462,2283]	2	hSpCas9	negative selection	5769358
157556205	157556228	2	-	27260156	A375	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.18687676744222004	[803]	[1057,1269,953,1022]	2	hSpCas9	negative selection	5769359
157550342	157550365	2	-	27260156	A375	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.4773663114738851	[669]	[836,1271,1361,925]	7	hSpCas9	negative selection	5833640
157587270	157587293	2	+	27260156	A375	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.20997828796222956	[623]	[727,777,1047,808]	3	hSpCas9	negative selection	5833641
157587327	157587350	2	-	27260156	A375	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.49699249153131364	[284]	[226,288,272,168]	-6	hSpCas9	negative selection	5833642
157556104	157556127	2	-	27260156	COLO741	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.26069522297720255	[504]	[954,709,674]	5	hSpCas9	negative selection	5890608
157550378	157550401	2	-	27260156	COLO741	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.010865817851484216	[2539]	[2955,3265,3533]	0	hSpCas9	negative selection	5890609
157556205	157556228	2	-	27260156	COLO741	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.10388708761885179	[803]	[1049,983,1258]	2	hSpCas9	negative selection	5890610
157550342	157550365	2	-	27260156	COLO741	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.2218877171000695	[669]	[1061,962,974]	5	hSpCas9	negative selection	5954891
157587270	157587293	2	+	27260156	COLO741	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.13254604792332897	[623]	[1139,668,835]	3	hSpCas9	negative selection	5954892
157587327	157587350	2	-	27260156	COLO741	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.2662343295502617	[284]	[276,373,257]	-5	hSpCas9	negative selection	5954893
157556104	157556127	2	-	27260156	CAL120	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.43166925073966816	[504]	[529,855,1103]	6	hSpCas9	negative selection	6011859
157550378	157550401	2	-	27260156	CAL120	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.013872931035460834	[2539]	[3828,2631,3035]	0	hSpCas9	negative selection	6011860
157556205	157556228	2	-	27260156	CAL120	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.08620224856678027	[803]	[1272,788,816]	-1	hSpCas9	negative selection	6011861
157550342	157550365	2	-	27260156	CAL120	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.38561726687664	[669]	[1684,815,859]	6	hSpCas9	negative selection	6076142
157587270	157587293	2	+	27260156	CAL120	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	-0.01951240172381774	[623]	[961,690,675]	0	hSpCas9	negative selection	6076143
157587327	157587350	2	-	27260156	CAL120	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.7389393037204169	[284]	[280,225,141]	-8	hSpCas9	negative selection	6076144
157556104	157556127	2	-	27260156	CADOES1	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.3643899305634425	[504]	[584,710,462,661]	6	hSpCas9	negative selection	6133110
157550378	157550401	2	-	27260156	CADOES1	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.14574038226488728	[2539]	[2367,2703,2733,2649]	2	hSpCas9	negative selection	6133111
157556205	157556228	2	-	27260156	CADOES1	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.3844907621352496	[803]	[575,521,573,620]	-6	hSpCas9	negative selection	6133112
157550342	157550365	2	-	27260156	CADOES1	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.34264442376642645	[669]	[747,1004,677,727]	6	hSpCas9	negative selection	6197393
157587270	157587293	2	+	27260156	CADOES1	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.3884642094337401	[623]	[865,777,724,665]	6	hSpCas9	negative selection	6197394
157587327	157587350	2	-	27260156	CADOES1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.4410080937294544	[284]	[114,144,276,245]	-6	hSpCas9	negative selection	6197395
157556104	157556127	2	-	27260156	EWS502	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.29855692876782564	[504]	[555,650,861,568]	5	hSpCas9	negative selection	6254361
157550378	157550401	2	-	27260156	EWS502	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.008422915199996606	[2539]	[2485,2383,2845,3172]	0	hSpCas9	negative selection	6254362
157556205	157556228	2	-	27260156	EWS502	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.025683323922494616	[803]	[586,896,953,1074]	0	hSpCas9	negative selection	6254363
157550342	157550365	2	-	27260156	EWS502	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	-0.016635758815418566	[669]	[628,674,948,552]	0	hSpCas9	negative selection	6318644
157587270	157587293	2	+	27260156	EWS502	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.041816917883434834	[623]	[598,542,650,960]	0	hSpCas9	negative selection	6318645
157587327	157587350	2	-	27260156	EWS502	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.28168745384029414	[284]	[381,149,205,240]	-5	hSpCas9	negative selection	6318646
157556104	157556127	2	-	27260156	EW8	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.45645645605673596	[504]	[655,659,501,447]	7	hSpCas9	negative selection	6375612
157550378	157550401	2	-	27260156	EW8	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.13756917420952375	[2539]	[2653,2042,2145,2269]	2	hSpCas9	negative selection	6375613
157556205	157556228	2	-	27260156	EW8	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.19728391722197092	[803]	[1090,590,702,645]	3	hSpCas9	negative selection	6375614
157550342	157550365	2	-	27260156	EW8	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.4215162018974872	[669]	[881,687,552,829]	7	hSpCas9	negative selection	6439895
157587270	157587293	2	+	27260156	EW8	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.1903253035356583	[623]	[744,619,460,518]	3	hSpCas9	negative selection	6439896
157587327	157587350	2	-	27260156	EW8	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.28728761270065706	[284]	[253,228,165,118]	-5	hSpCas9	negative selection	6439897
157556104	157556127	2	-	27260156	CORL105	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.4513762260293553	[504]	[796,802,1046,623]	8	hSpCas9	negative selection	6496863
157550378	157550401	2	-	27260156	CORL105	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.031149767573756648	[2539]	[3232,2330,3844,2400]	0	hSpCas9	negative selection	6496864
157556205	157556228	2	-	27260156	CORL105	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.18314888530722295	[803]	[889,731,993,729]	-3	hSpCas9	negative selection	6496865
157550342	157550365	2	-	27260156	CORL105	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.17358956103031564	[669]	[837,791,978,943]	3	hSpCas9	negative selection	6561146
157587270	157587293	2	+	27260156	CORL105	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.22296758074520345	[623]	[855,877,909,774]	4	hSpCas9	negative selection	6561147
157587327	157587350	2	-	27260156	CORL105	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.5059902622702722	[284]	[285,140,352,181]	-7	hSpCas9	negative selection	6561148
157556104	157556127	2	-	27260156	HS294T	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.6254745906013237	[504]	[273,325,192,434]	7	hSpCas9	negative selection	6618114
157550378	157550401	2	-	27260156	HS294T	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.12075326015552301	[2539]	[1115,943,1085,1131]	1	hSpCas9	negative selection	6618115
157556205	157556228	2	-	27260156	HS294T	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.12625921805613927	[803]	[350,315,347,340]	1	hSpCas9	negative selection	6618116
157550342	157550365	2	-	27260156	HS294T	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.6543010621020483	[669]	[636,286,365,303]	8	hSpCas9	negative selection	6682397
157587270	157587293	2	+	27260156	HS294T	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.31192452766802775	[623]	[170,249,361,453]	4	hSpCas9	negative selection	6682398
157587327	157587350	2	-	27260156	HS294T	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.06760435696175926	[284]	[42,185,101,89]	-1	hSpCas9	negative selection	6682399
157556104	157556127	2	-	27260156	HCC44	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.39173697509917316	[504]	[828,462,1013,777]	6	hSpCas9	negative selection	6739365
157550378	157550401	2	-	27260156	HCC44	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.011570066514017707	[2539]	[3232,2215,3528,2646]	0	hSpCas9	negative selection	6739366
157556205	157556228	2	-	27260156	HCC44	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.15221333497034173	[803]	[894,759,963,691]	-2	hSpCas9	negative selection	6739367
157550342	157550365	2	-	27260156	HCC44	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.008630755428220227	[669]	[956,545,879,729]	0	hSpCas9	negative selection	6803648
157587270	157587293	2	+	27260156	HCC44	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.22801819849670318	[623]	[764,689,1108,798]	3	hSpCas9	negative selection	6803649
157587327	157587350	2	-	27260156	HCC44	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.8188489427504132	[284]	[228,173,212,125]	-8	hSpCas9	negative selection	6803650
157556104	157556127	2	-	27260156	G402	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.6372203556868651	[504]	[1009,1100,1038,707]	7	hSpCas9	negative selection	6860616
157550378	157550401	2	-	27260156	G402	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.2710431626760559	[2539]	[2968,3012,2145,2235]	-3	hSpCas9	negative selection	6860617
157556205	157556228	2	-	27260156	G402	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.4319602073929586	[803]	[949,905,480,616]	-5	hSpCas9	negative selection	6860618
157550342	157550365	2	-	27260156	G402	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.487188224537495	[669]	[565,1074,1164,1659]	6	hSpCas9	negative selection	6924899
157587270	157587293	2	+	27260156	G402	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.4719760171053324	[623]	[1244,904,1144,948]	6	hSpCas9	negative selection	6924900
157587327	157587350	2	-	27260156	G402	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.06451958731489826	[284]	[153,553,190,412]	-1	hSpCas9	negative selection	6924901
157556104	157556127	2	-	27260156	L33	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	-0.25004585373818294	[504]	[343,190,254,483]	-5	hSpCas9	negative selection	6981867
157550378	157550401	2	-	27260156	L33	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.14047601058706904	[2539]	[3014,1146,1620,2798]	3	hSpCas9	negative selection	6981868
157556205	157556228	2	-	27260156	L33	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.19468118841887405	[803]	[800,281,337,778]	-4	hSpCas9	negative selection	6981869
157550342	157550365	2	-	27260156	L33	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.07508945957263691	[669]	[857,302,315,717]	1	hSpCas9	negative selection	7046150
157587270	157587293	2	+	27260156	L33	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.14931843267625672	[623]	[707,271,400,756]	3	hSpCas9	negative selection	7046151
157587327	157587350	2	-	27260156	L33	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.4850510740256514	[284]	[239,84,125,165]	-8	hSpCas9	negative selection	7046152
157556104	157556127	2	-	27260156	K562	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.4709873910111532	[504]	[669,675,720,442]	6	hSpCas9	negative selection	7103118
157550378	157550401	2	-	27260156	K562	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.3402617224443185	[2539]	[2067,1980,1437,1673]	-4	hSpCas9	negative selection	7103119
157556205	157556228	2	-	27260156	K562	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.40757826124322805	[803]	[571,490,344,719]	-5	hSpCas9	negative selection	7103120
157550342	157550365	2	-	27260156	K562	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.5577636181036384	[669]	[794,1082,696,920]	7	hSpCas9	negative selection	7167401
157587270	157587293	2	+	27260156	K562	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.5635486578175961	[623]	[768,965,646,883]	7	hSpCas9	negative selection	7167402
157587327	157587350	2	-	27260156	K562	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.44399949974644815	[284]	[147,208,367,33]	-5	hSpCas9	negative selection	7167403
157556104	157556127	2	-	27260156	HT29	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.26817446447338433	[504]	[983,731,604,658]	5	hSpCas9	negative selection	7224369
157550378	157550401	2	-	27260156	HT29	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.06517121594790476	[2539]	[3799,3489,2956,2773]	1	hSpCas9	negative selection	7224370
157556205	157556228	2	-	27260156	HT29	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.10607102551597336	[803]	[1070,995,753,833]	-2	hSpCas9	negative selection	7224371
157550342	157550365	2	-	27260156	HT29	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.3461894587097367	[669]	[1028,930,1071,1085]	6	hSpCas9	negative selection	7288652
157587270	157587293	2	+	27260156	HT29	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.18058818316151531	[623]	[1053,820,896,692]	3	hSpCas9	negative selection	7288653
157587327	157587350	2	-	27260156	HT29	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.41176161694075486	[284]	[320,300,183,243]	-6	hSpCas9	negative selection	7288654
157556104	157556127	2	-	27260156	MHHES1	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.33164882661645795	[504]	[826,1018,710,406]	6	hSpCas9	negative selection	7345620
157550378	157550401	2	-	27260156	MHHES1	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.025494366379219535	[2539]	[2570,3257,2711,2681]	0	hSpCas9	negative selection	7345621
157556205	157556228	2	-	27260156	MHHES1	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.4610585797965314	[803]	[609,862,600,575]	-7	hSpCas9	negative selection	7345622
157550342	157550365	2	-	27260156	MHHES1	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.28461485020496247	[669]	[1033,1160,686,830]	5	hSpCas9	negative selection	7409903
157587270	157587293	2	+	27260156	MHHES1	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.2863324051922839	[623]	[773,1139,853,696]	5	hSpCas9	negative selection	7409904
157587327	157587350	2	-	27260156	MHHES1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.6848143118722344	[284]	[336,117,212,146]	-8	hSpCas9	negative selection	7409905
157556104	157556127	2	-	27260156	MEWO	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.43054486213080595	[504]	[715,732,475]	8	hSpCas9	negative selection	7466871
157550378	157550401	2	-	27260156	MEWO	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.19038798474624574	[2539]	[3387,2530,2346]	4	hSpCas9	negative selection	7466872
157556205	157556228	2	-	27260156	MEWO	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.021938031355624665	[803]	[839,651,749]	0	hSpCas9	negative selection	7466873
157550342	157550365	2	-	27260156	MEWO	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.16848373848734632	[669]	[960,697,503]	4	hSpCas9	negative selection	7531154
157587270	157587293	2	+	27260156	MEWO	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	-0.13618023182710182	[623]	[517,518,553]	-3	hSpCas9	negative selection	7531155
157587327	157587350	2	-	27260156	MEWO	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.46621745121759817	[284]	[227,142,214]	-7	hSpCas9	negative selection	7531156
157556104	157556127	2	-	27260156	LNCAPCLONEFGC	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.3640462777512885	[504]	[598,539,590,627]	6	hSpCas9	negative selection	7588122
157550378	157550401	2	-	27260156	LNCAPCLONEFGC	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.03076291884487592	[2539]	[2184,2335,2623,2299]	0	hSpCas9	negative selection	7588123
157556205	157556228	2	-	27260156	LNCAPCLONEFGC	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.1841005168015336	[803]	[716,701,957,961]	3	hSpCas9	negative selection	7588124
157550342	157550365	2	-	27260156	LNCAPCLONEFGC	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.492453600690098	[669]	[690,797,1017,938]	7	hSpCas9	negative selection	7652405
157587270	157587293	2	+	27260156	LNCAPCLONEFGC	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.17058348741481494	[623]	[656,605,777,525]	2	hSpCas9	negative selection	7652406
157587327	157587350	2	-	27260156	LNCAPCLONEFGC	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.16785232694870522	[284]	[208,209,284,224]	-3	hSpCas9	negative selection	7652407
157556104	157556127	2	-	27260156	PANC0327	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.41435824034462715	[504]	[933,462,479,558]	6	hSpCas9	negative selection	7709373
157550378	157550401	2	-	27260156	PANC0327	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.04913824228056729	[2539]	[2121,2055,2593,2583]	0	hSpCas9	negative selection	7709374
157556205	157556228	2	-	27260156	PANC0327	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.028163244041139124	[803]	[876,475,806,684]	0	hSpCas9	negative selection	7709375
157550342	157550365	2	-	27260156	PANC0327	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.5719491636576702	[669]	[1023,782,788,966]	8	hSpCas9	negative selection	7773656
157587270	157587293	2	+	27260156	PANC0327	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.34136316862307364	[623]	[739,513,626,954]	5	hSpCas9	negative selection	7773657
157587327	157587350	2	-	27260156	PANC0327	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.607190002178371	[284]	[136,145,198,182]	-7	hSpCas9	negative selection	7773658
157556104	157556127	2	-	27260156	NCIH2009	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.2181510138116179	[504]	[898,671,907]	3	hSpCas9	negative selection	7830624
157550378	157550401	2	-	27260156	NCIH2009	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.3374797504232667	[2539]	[3188,2707,2600]	-4	hSpCas9	negative selection	7830625
157556205	157556228	2	-	27260156	NCIH2009	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.013277164393992735	[803]	[1254,850,1263]	0	hSpCas9	negative selection	7830626
157550342	157550365	2	-	27260156	NCIH2009	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.24587390774750528	[669]	[1429,1079,881]	3	hSpCas9	negative selection	7894907
157587270	157587293	2	+	27260156	NCIH2009	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.058118401739034486	[623]	[828,736,1142]	0	hSpCas9	negative selection	7894908
157587327	157587350	2	-	27260156	NCIH2009	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.5634205772068291	[284]	[394,308,127]	-6	hSpCas9	negative selection	7894909
157556104	157556127	2	-	27260156	NCIH1373	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.7316072571876365	[504]	[1002,1056,555,303]	7	hSpCas9	negative selection	7951875
157550378	157550401	2	-	27260156	NCIH1373	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.057695101734005494	[2539]	[3371,2974,2927,683]	0	hSpCas9	negative selection	7951876
157556205	157556228	2	-	27260156	NCIH1373	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.32470770841719226	[803]	[797,559,785,199]	-3	hSpCas9	negative selection	7951877
157550342	157550365	2	-	27260156	NCIH1373	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.994320940864284	[669]	[1683,797,1989,421]	8	hSpCas9	negative selection	8016158
157587270	157587293	2	+	27260156	NCIH1373	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.2073443473804693	[623]	[1121,831,653,172]	2	hSpCas9	negative selection	8016159
157587327	157587350	2	-	27260156	NCIH1373	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-1.1575476636321662	[284]	[113,107,248,24]	-8	hSpCas9	negative selection	8016160
157556104	157556127	2	-	27260156	PATU8902	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.31260232544104816	[504]	[894,1017,556,1129]	3	hSpCas9	negative selection	8073126
157550378	157550401	2	-	27260156	PATU8902	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.10210111544716627	[2539]	[4369,3940,2799,4365]	1	hSpCas9	negative selection	8073127
157556205	157556228	2	-	27260156	PATU8902	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.150777182713292	[803]	[1438,1182,1222,1102]	1	hSpCas9	negative selection	8073128
157550342	157550365	2	-	27260156	PATU8902	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.8431255600749675	[669]	[2263,1584,887,2204]	8	hSpCas9	negative selection	8137409
157587270	157587293	2	+	27260156	PATU8902	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.030212808739348063	[623]	[1257,706,679,953]	0	hSpCas9	negative selection	8137410
157587327	157587350	2	-	27260156	PATU8902	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.290172823992341	[284]	[622,443,349,562]	3	hSpCas9	negative selection	8137411
157556104	157556127	2	-	27260156	PANC1	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.8146179098861516	[504]	[706,823,801,725]	9	hSpCas9	negative selection	8194377
157550378	157550401	2	-	27260156	PANC1	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.09865050195334568	[2539]	[2160,3366,2227,1845]	1	hSpCas9	negative selection	8194378
157556205	157556228	2	-	27260156	PANC1	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.38146158254168105	[803]	[416,721,661,378]	-5	hSpCas9	negative selection	8194379
157550342	157550365	2	-	27260156	PANC1	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.4385636309499341	[669]	[679,874,764,803]	7	hSpCas9	negative selection	8258660
157587270	157587293	2	+	27260156	PANC1	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.350826980712091	[623]	[757,737,736,525]	5	hSpCas9	negative selection	8258661
157587327	157587350	2	-	27260156	PANC1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.2677928758330964	[284]	[111,194,181,303]	-4	hSpCas9	negative selection	8258662
157556104	157556127	2	-	27260156	PANC0813	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.16531432115912942	[504]	[788,561,599,716]	2	hSpCas9	negative selection	8315628
157550378	157550401	2	-	27260156	PANC0813	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.004165888966494613	[2539]	[3079,3227,2948,2664]	0	hSpCas9	negative selection	8315629
157556205	157556228	2	-	27260156	PANC0813	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.12700441266716245	[803]	[985,1014,1058,1057]	2	hSpCas9	negative selection	8315630
157550342	157550365	2	-	27260156	PANC0813	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.17288642897344053	[669]	[857,532,998,1140]	3	hSpCas9	negative selection	8379911
157587270	157587293	2	+	27260156	PANC0813	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.07148574335013824	[623]	[957,769,767,609]	1	hSpCas9	negative selection	8379912
157587327	157587350	2	-	27260156	PANC0813	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.25251607190998254	[284]	[822,312,313,194]	4	hSpCas9	negative selection	8379913
157556104	157556127	2	-	27260156	RDES	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.4522709117731732	[504]	[664,721,834,999]	7	hSpCas9	negative selection	8436879
157550378	157550401	2	-	27260156	RDES	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.0658754037696685	[2539]	[2270,2462,3026,3593]	-1	hSpCas9	negative selection	8436880
157556205	157556228	2	-	27260156	RDES	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.15189698031574428	[803]	[644,779,831,1139]	-3	hSpCas9	negative selection	8436881
157550342	157550365	2	-	27260156	RDES	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.4134650266071268	[669]	[976,1084,911,1108]	6	hSpCas9	negative selection	8501162
157587270	157587293	2	+	27260156	RDES	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.13381685764872137	[623]	[808,628,822,888]	2	hSpCas9	negative selection	8501163
157587327	157587350	2	-	27260156	RDES	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.8972954576810436	[284]	[140,184,168,215]	-9	hSpCas9	negative selection	8501164
157556104	157556127	2	-	27260156	PC3	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.2880019056329235	[504]	[477,624,859,574]	6	hSpCas9	negative selection	8558130
157550378	157550401	2	-	27260156	PC3	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.13963236890280362	[2539]	[1750,2191,5709,2867]	3	hSpCas9	negative selection	8558131
157556205	157556228	2	-	27260156	PC3	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.09495913682919932	[803]	[447,908,1645,831]	2	hSpCas9	negative selection	8558132
157550342	157550365	2	-	27260156	PC3	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	-0.03287062355611603	[669]	[403,672,1140,626]	0	hSpCas9	negative selection	8622413
157587270	157587293	2	+	27260156	PC3	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.007769345915082326	[623]	[393,782,817,609]	0	hSpCas9	negative selection	8622414
157587327	157587350	2	-	27260156	PC3	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.40307695934893084	[284]	[108,233,464,174]	-7	hSpCas9	negative selection	8622415
157556104	157556127	2	-	27260156	PATU8988T	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	-0.09783339345820104	[504]	[301,666,390,486]	-2	hSpCas9	negative selection	8679381
157550378	157550401	2	-	27260156	PATU8988T	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.25643723259505125	[2539]	[3263,2876,2345,3269]	4	hSpCas9	negative selection	8679382
157556205	157556228	2	-	27260156	PATU8988T	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.22342463733117013	[803]	[1322,848,768,663]	4	hSpCas9	negative selection	8679383
157550342	157550365	2	-	27260156	PATU8988T	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	-0.04294825409530295	[669]	[731,728,491,566]	0	hSpCas9	negative selection	8743664
157587270	157587293	2	+	27260156	PATU8988T	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.30342311952608075	[623]	[1051,658,667,576]	5	hSpCas9	negative selection	8743665
157587327	157587350	2	-	27260156	PATU8988T	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.1531289788804009	[284]	[140,273,181,409]	-3	hSpCas9	negative selection	8743666
157556104	157556127	2	-	27260156	T47D	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.380242779401363	[504]	[788,736,755,783]	7	hSpCas9	negative selection	8800632
157550378	157550401	2	-	27260156	T47D	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.020052501724170835	[2539]	[2979,2590,3219,3249]	0	hSpCas9	negative selection	8800633
157556205	157556228	2	-	27260156	T47D	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.008006170349230679	[803]	[1062,766,944,1009]	0	hSpCas9	negative selection	8800634
157550342	157550365	2	-	27260156	T47D	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.258525855757878	[669]	[955,944,822,1013]	5	hSpCas9	negative selection	8864915
157587270	157587293	2	+	27260156	T47D	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.20623910519842376	[623]	[753,852,757,993]	4	hSpCas9	negative selection	8864916
157587327	157587350	2	-	27260156	T47D	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.26091554719383336	[284]	[345,258,246,257]	-5	hSpCas9	negative selection	8864917
157556104	157556127	2	-	27260156	SU8686	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.10281867165633903	[504]	[529,469,574,590]	1	hSpCas9	negative selection	8921883
157550378	157550401	2	-	27260156	SU8686	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.01823085115578804	[2539]	[2274,2380,2287,3118]	0	hSpCas9	negative selection	8921884
157556205	157556228	2	-	27260156	SU8686	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.16991272662528434	[803]	[934,779,915,972]	3	hSpCas9	negative selection	8921885
157550342	157550365	2	-	27260156	SU8686	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.2155230586624831	[669]	[631,785,908,769]	3	hSpCas9	negative selection	8986166
157587270	157587293	2	+	27260156	SU8686	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	-0.0162933152825	[623]	[598,567,622,668]	0	hSpCas9	negative selection	8986167
157587327	157587350	2	-	27260156	SU8686	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.13913228497015606	[284]	[242,226,348,204]	-2	hSpCas9	negative selection	8986168
157556104	157556127	2	-	27260156	SKES1	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.2129556611649457	[504]	[686,654,404,604]	4	hSpCas9	negative selection	9043134
157550378	157550401	2	-	27260156	SKES1	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.07566860815100762	[2539]	[2632,3222,2765,2152]	1	hSpCas9	negative selection	9043135
157556205	157556228	2	-	27260156	SKES1	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.1477402571010611	[803]	[822,841,730,541]	-3	hSpCas9	negative selection	9043136
157550342	157550365	2	-	27260156	SKES1	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.2545977586823107	[669]	[1077,713,839,600]	5	hSpCas9	negative selection	9107417
157587270	157587293	2	+	27260156	SKES1	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.24340179805721668	[623]	[674,744,717,787]	5	hSpCas9	negative selection	9107418
157587327	157587350	2	-	27260156	SKES1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.14971385362254686	[284]	[350,222,209,248]	-3	hSpCas9	negative selection	9107419
157556104	157556127	2	-	27260156	TOV112D	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.5673321609410807	[504]	[555,943,1025,508]	8	hSpCas9	negative selection	9164385
157550378	157550401	2	-	27260156	TOV112D	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.10651548037259273	[2539]	[3178,3173,2616,2141]	2	hSpCas9	negative selection	9164386
157556205	157556228	2	-	27260156	TOV112D	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.048690453444670934	[803]	[931,984,772,689]	1	hSpCas9	negative selection	9164387
157550342	157550365	2	-	27260156	TOV112D	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.6167047163175691	[669]	[766,2222,660,742]	9	hSpCas9	negative selection	9228668
157587270	157587293	2	+	27260156	TOV112D	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.13713441032189738	[623]	[793,889,475,647]	2	hSpCas9	negative selection	9228669
157587327	157587350	2	-	27260156	TOV112D	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.42092202330714634	[284]	[339,157,189,162]	-7	hSpCas9	negative selection	9228670
157556104	157556127	2	-	27260156	TC71	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.04097935325481174	[504]	[433,604,531,666]	1	hSpCas9	negative selection	9285636
157550378	157550401	2	-	27260156	TC71	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	0.1544468309700031	[2539]	[3046,2910,2737,3460]	4	hSpCas9	negative selection	9285637
157556205	157556228	2	-	27260156	TC71	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	0.05303461458185954	[803]	[795,956,923,900]	1	hSpCas9	negative selection	9285638
157550342	157550365	2	-	27260156	TC71	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.05498211427913946	[669]	[682,776,665,869]	1	hSpCas9	negative selection	9349919
157587270	157587293	2	+	27260156	TC71	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.07607337542794756	[623]	[539,897,679,706]	2	hSpCas9	negative selection	9349920
157587327	157587350	2	-	27260156	TC71	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.3832358815601008	[284]	[299,164,229,240]	-8	hSpCas9	negative selection	9349921
157556104	157556127	2	-	27260156	TC32	viability	ATTTATGATGTGACCGCCTCTGG	ACVR1C	ENSG00000123612	0.4541335526697066	[504]	[547,573,787,719]	7	hSpCas9	negative selection	9406887
157550378	157550401	2	-	27260156	TC32	viability	TTGGTTAGGTCTACCTCTGTTGG	ACVR1C	ENSG00000123612	-0.0344268313194398	[2539]	[2471,1601,2853,2619]	0	hSpCas9	negative selection	9406888
157556205	157556228	2	-	27260156	TC32	viability	AGGGTCGACAGTGCTCCTACAGG	ACVR1C	ENSG00000123612	-0.337509827875372	[803]	[642,483,690,588]	-6	hSpCas9	negative selection	9406889
157550342	157550365	2	-	27260156	TC32	viability	TGCAAGGACGATTGTGCTTCAGG	ACVR1C	ENSG00000123612	0.6217830702877364	[669]	[878,759,1223,1095]	9	hSpCas9	negative selection	9471170
157587270	157587293	2	+	27260156	TC32	viability	AAGACTTGAGCATTCAGTTCTGG	ACVR1C	ENSG00000123612	0.22562905414149398	[623]	[605,425,1019,826]	4	hSpCas9	negative selection	9471171
157587327	157587350	2	-	27260156	TC32	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.46689442277313786	[284]	[229,108,208,248]	-7	hSpCas9	negative selection	9471172
157541106	157541129	2	-	27869803	HPAFII	viability after 27 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	-0.26785783845837285	[187]	[68,92,NaN]	-2	hSpCas9	negative selection	9571974
157542705	157542728	2	-	27869803	HPAFII	viability after 27 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.2874214532567253	[154]	[147,58,NaN]	2	hSpCas9	negative selection	9571975
157544502	157544525	2	-	27869803	HPAFII	viability after 27 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.2646432141753833	[488]	[93,313,NaN]	-2	hSpCas9	negative selection	9571976
157556224	157556247	2	-	27869803	HPAFII	viability after 27 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.916191866317521	[247]	[67,69,NaN]	-6	hSpCas9	negative selection	9571977
157587186	157587209	2	-	27869803	HPAFII	viability after 27 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	1.1583202184256711	[140]	[219,119,NaN]	8	hSpCas9	negative selection	9571978
157587327	157587350	2	-	27869803	HPAFII	viability after 27 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.5449107301317876	[397]	[571,82,NaN]	4	hSpCas9	negative selection	9571979
157541106	157541129	2	-	27869803	HPAFII	viability after 15 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	-0.12919466754852638	[187]	[275,127,NaN]	-1	hSpCas9	negative selection	9654423
157542705	157542728	2	-	27869803	HPAFII	viability after 15 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	-0.04820056870547473	[154]	[260,98,NaN]	0	hSpCas9	negative selection	9654424
157544502	157544525	2	-	27869803	HPAFII	viability after 15 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.5499811152500179	[488]	[300,394,NaN]	-5	hSpCas9	negative selection	9654425
157556224	157556247	2	-	27869803	HPAFII	viability after 15 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	0.09137008306978361	[247]	[381,222,NaN]	1	hSpCas9	negative selection	9654426
157587186	157587209	2	-	27869803	HPAFII	viability after 15 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.6978279132062585	[140]	[267,231,NaN]	7	hSpCas9	negative selection	9654427
157587327	157587350	2	-	27869803	HPAFII	viability after 15 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.16220954245669117	[397]	[602,244,NaN]	-2	hSpCas9	negative selection	9654428
157541106	157541129	2	-	27869803	ASPC1	viability after 36 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.7225620804767385	[369]	[287,171,190]	7	hSpCas9	negative selection	9736872
157542705	157542728	2	-	27869803	ASPC1	viability after 36 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.5591524160990549	[333]	[44,439,45]	5	hSpCas9	negative selection	9736873
157544502	157544525	2	-	27869803	ASPC1	viability after 36 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.8546192826386761	[1178]	[277,142,256]	-7	hSpCas9	negative selection	9736874
157556224	157556247	2	-	27869803	ASPC1	viability after 36 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.4776728787072856	[952]	[486,164,120]	-5	hSpCas9	negative selection	9736875
157587186	157587209	2	-	27869803	ASPC1	viability after 36 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.3995848045213713	[618]	[189,295,339]	4	hSpCas9	negative selection	9736876
157587327	157587350	2	-	27869803	ASPC1	viability after 36 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.08772644149008785	[787]	[189,605,111]	0	hSpCas9	negative selection	9736877
157541106	157541129	2	-	27869803	PATU8988S	viability after 35 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.006022214928371072	[308]	[111,137,NaN]	0	hSpCas9	negative selection	9819321
157542705	157542728	2	-	27869803	PATU8988S	viability after 35 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.5108649575604337	[345]	[225,170,NaN]	6	hSpCas9	negative selection	9819322
157544502	157544525	2	-	27869803	PATU8988S	viability after 35 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.12872438100331096	[957]	[308,396,NaN]	-1	hSpCas9	negative selection	9819323
157556224	157556247	2	-	27869803	PATU8988S	viability after 35 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	0.6539067678530086	[746]	[416,529,NaN]	7	hSpCas9	negative selection	9819324
157587186	157587209	2	-	27869803	PATU8988S	viability after 35 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.2955364396228458	[541]	[114,240,NaN]	-3	hSpCas9	negative selection	9819325
157587327	157587350	2	-	27869803	PATU8988S	viability after 35 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.03888139105757593	[666]	[263,287,NaN]	0	hSpCas9	negative selection	9819326
157541106	157541129	2	-	27869803	PATU8988S	viability after 31 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	0.30105800484848255	[308]	[164,134,NaN]	4	hSpCas9	negative selection	9901770
157542705	157542728	2	-	27869803	PATU8988S	viability after 31 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.26543904205924423	[345]	[138,199,NaN]	3	hSpCas9	negative selection	9901771
157544502	157544525	2	-	27869803	PATU8988S	viability after 31 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	-0.1914202293901377	[957]	[191,515,NaN]	-2	hSpCas9	negative selection	9901772
157556224	157556247	2	-	27869803	PATU8988S	viability after 31 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	0.351255055377156	[746]	[247,547,NaN]	4	hSpCas9	negative selection	9901773
157587186	157587209	2	-	27869803	PATU8988S	viability after 31 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	-0.10131372905787116	[541]	[116,308,NaN]	-1	hSpCas9	negative selection	9901774
157587327	157587350	2	-	27869803	PATU8988S	viability after 31 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.11005003523929141	[666]	[190,316,NaN]	-1	hSpCas9	negative selection	9901775
157541106	157541129	2	-	27869803	HPAFII	viability after 35 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	-0.42427996828900016	[187]	[37,107,NaN]	-3	hSpCas9	negative selection	9984219
157542705	157542728	2	-	27869803	HPAFII	viability after 35 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.35851866113981606	[154]	[133,62,NaN]	2	hSpCas9	negative selection	9984220
157544502	157544525	2	-	27869803	HPAFII	viability after 35 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.1780678084176065	[488]	[74,510,NaN]	1	hSpCas9	negative selection	9984221
157556224	157556247	2	-	27869803	HPAFII	viability after 35 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.11574989580067478	[247]	[89,144,NaN]	0	hSpCas9	negative selection	9984222
157587186	157587209	2	-	27869803	HPAFII	viability after 35 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	1.2084100686601216	[140]	[179,147,NaN]	7	hSpCas9	negative selection	9984223
157587327	157587350	2	-	27869803	HPAFII	viability after 35 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	1.2676575492165827	[397]	[724,214,NaN]	8	hSpCas9	negative selection	9984224
157541106	157541129	2	-	27869803	HPAFII	viability after 31 days	TGGTTTACTGGGAAATAGCCCGG	ACVR1C	ENSG00000123612	-0.4148304080107953	[187]	[59,99,NaN]	-3	hSpCas9	negative selection	10066668
157542705	157542728	2	-	27869803	HPAFII	viability after 31 days	ATCCTAAAGTGGGAACCAAGAGG	ACVR1C	ENSG00000123612	0.7413428573939792	[154]	[165,122,NaN]	5	hSpCas9	negative selection	10066669
157544502	157544525	2	-	27869803	HPAFII	viability after 31 days	CGTGGCTGGAATGATCAAGCTGG	ACVR1C	ENSG00000123612	0.03146402777745083	[488]	[67,511,NaN]	0	hSpCas9	negative selection	10066670
157556224	157556247	2	-	27869803	HPAFII	viability after 31 days	CTGACAGTATGGGCATGCCAGGG	ACVR1C	ENSG00000123612	-0.12356496694425867	[247]	[99,157,NaN]	-1	hSpCas9	negative selection	10066671
157587186	157587209	2	-	27869803	HPAFII	viability after 31 days	ATAACACTGCACCTTCCAACAGG	ACVR1C	ENSG00000123612	0.820376835449633	[140]	[144,133,NaN]	6	hSpCas9	negative selection	10066672
157587327	157587350	2	-	27869803	HPAFII	viability after 31 days	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.7485372231935304	[397]	[559,173,NaN]	5	hSpCas9	negative selection	10066673
157587327	157587350	2	-	28162770	P31FUJ	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.11102834437204523	[352]	[447]	1	hSpCas9	negative selection	10106624
157541131	157541154	2	-	28162770	P31FUJ	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.44643520099664546	[463]	[742]	5	hSpCas9	negative selection	10106625
157538585	157538608	2	-	28162770	P31FUJ	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-0.4630998238361727	[182]	[155]	-4	hSpCas9	negative selection	10106626
157541103	157541126	2	-	28162770	P31FUJ	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-0.7967030896077052	[33]	[22]	-6	hSpCas9	negative selection	10106627
157587316	157587339	2	-	28162770	P31FUJ	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.38017467247637415	[67]	[103]	4	hSpCas9	negative selection	10106628
157544483	157544506	2	-	28162770	P31FUJ	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.3268174481923143	[133]	[394]	9	hSpCas9	negative selection	10106629
157542773	157542796	2	-	28162770	P31FUJ	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.4178635433576071	[371]	[583]	4	hSpCas9	negative selection	10106630
157541088	157541111	2	+	28162770	P31FUJ	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.3099908420628381	[728]	[1061]	3	hSpCas9	negative selection	10106631
157544503	157544526	2	+	28162770	P31FUJ	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.6290668767221288	[114]	[208]	7	hSpCas9	negative selection	10106632
157587175	157587198	2	+	28162770	P31FUJ	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.6547230663272088	[859]	[1590]	7	hSpCas9	negative selection	10106633
157587327	157587350	2	-	28162770	TF1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[251]	1	hSpCas9	negative selection	10275990
157541131	157541154	2	-	28162770	TF1	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[410]	1	hSpCas9	negative selection	10275991
157538585	157538608	2	-	28162770	TF1	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10275992
157541103	157541126	2	-	28162770	TF1	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10275993
157587316	157587339	2	-	28162770	TF1	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10275994
157544483	157544506	2	-	28162770	TF1	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[149]	1	hSpCas9	negative selection	10275995
157542773	157542796	2	-	28162770	TF1	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[286]	1	hSpCas9	negative selection	10275996
157541088	157541111	2	+	28162770	TF1	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[568]	1	hSpCas9	negative selection	10275997
157544503	157544526	2	+	28162770	TF1	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[164]	1	hSpCas9	negative selection	10275998
157587175	157587198	2	+	28162770	TF1	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	NaN	[NaN]	[1145]	1	hSpCas9	negative selection	10275999
157587327	157587350	2	-	28162770	SKM1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.03350580321571728	[76]	[132]	0	hSpCas9	negative selection	10445356
157541131	157541154	2	-	28162770	SKM1	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.014499569695115122	[125]	[224]	0	hSpCas9	negative selection	10445357
157538585	157538608	2	-	28162770	SKM1	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	0.09226842795211056	[51]	[97]	0	hSpCas9	negative selection	10445358
157541103	157541126	2	-	28162770	SKM1	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	0.8784380201190867	[11]	[38]	8	hSpCas9	negative selection	10445359
157587316	157587339	2	-	28162770	SKM1	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	-0.03773038907744275	[17]	[30]	0	hSpCas9	negative selection	10445360
157544483	157544506	2	-	28162770	SKM1	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.5199178720528228	[42]	[108]	5	hSpCas9	negative selection	10445361
157542773	157542796	2	-	28162770	SKM1	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.3355395789644745	[77]	[173]	3	hSpCas9	negative selection	10445362
157541088	157541111	2	+	28162770	SKM1	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.15255328542053137	[142]	[280]	1	hSpCas9	negative selection	10445363
157544503	157544526	2	+	28162770	SKM1	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	-0.3408750082853892	[47]	[66]	-3	hSpCas9	negative selection	10445364
157587175	157587198	2	+	28162770	SKM1	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.3633533439899126	[185]	[422]	3	hSpCas9	negative selection	10445365
157587327	157587350	2	-	28162770	SKM1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.03350580321571728	[76]	[132]	0	hSpCas9	negative selection	10614722
157541131	157541154	2	-	28162770	SKM1	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.014499569695115122	[125]	[224]	0	hSpCas9	negative selection	10614723
157538585	157538608	2	-	28162770	SKM1	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	0.09226842795211056	[51]	[97]	0	hSpCas9	negative selection	10614724
157541103	157541126	2	-	28162770	SKM1	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	0.8784380201190867	[11]	[38]	8	hSpCas9	negative selection	10614725
157587316	157587339	2	-	28162770	SKM1	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	-0.03773038907744275	[17]	[30]	0	hSpCas9	negative selection	10614726
157544483	157544506	2	-	28162770	SKM1	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.5199178720528228	[42]	[108]	5	hSpCas9	negative selection	10614727
157542773	157542796	2	-	28162770	SKM1	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.3355395789644745	[77]	[173]	3	hSpCas9	negative selection	10614728
157541088	157541111	2	+	28162770	SKM1	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.15255328542053137	[142]	[280]	1	hSpCas9	negative selection	10614729
157544503	157544526	2	+	28162770	SKM1	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	-0.3408750082853892	[47]	[66]	-3	hSpCas9	negative selection	10614730
157587175	157587198	2	+	28162770	SKM1	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.3633533439899126	[185]	[422]	3	hSpCas9	negative selection	10614731
157587327	157587350	2	-	28162770	PL21	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.31503455607497377	[342]	[119]	-2	hSpCas9	negative selection	10784088
157541131	157541154	2	-	28162770	PL21	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.018809849774758414	[380]	[167]	0	hSpCas9	negative selection	10784089
157538585	157538608	2	-	28162770	PL21	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	1.3291260552093982	[138]	[151]	9	hSpCas9	negative selection	10784090
157541103	157541126	2	-	28162770	PL21	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-1.2019588290820256	[36]	[6]	-7	hSpCas9	negative selection	10784091
157587316	157587339	2	-	28162770	PL21	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.6075639296582888	[94]	[62]	5	hSpCas9	negative selection	10784092
157544483	157544506	2	-	28162770	PL21	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.286112837599173	[113]	[120]	9	hSpCas9	negative selection	10784093
157542773	157542796	2	-	28162770	PL21	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.8934782762552682	[234]	[189]	7	hSpCas9	negative selection	10784094
157541088	157541111	2	+	28162770	PL21	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.03348974507986879	[549]	[244]	0	hSpCas9	negative selection	10784095
157544503	157544526	2	+	28162770	PL21	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.505765897047582	[177]	[109]	4	hSpCas9	negative selection	10784096
157587175	157587198	2	+	28162770	PL21	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.9185237829138007	[546]	[449]	7	hSpCas9	negative selection	10784097
157587327	157587350	2	-	28162770	P31FUJ	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.11102834437204523	[352]	[447]	1	hSpCas9	negative selection	10953454
157541131	157541154	2	-	28162770	P31FUJ	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.44643520099664546	[463]	[742]	5	hSpCas9	negative selection	10953455
157538585	157538608	2	-	28162770	P31FUJ	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-0.4630998238361727	[182]	[155]	-4	hSpCas9	negative selection	10953456
157541103	157541126	2	-	28162770	P31FUJ	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-0.7967030896077052	[33]	[22]	-6	hSpCas9	negative selection	10953457
157587316	157587339	2	-	28162770	P31FUJ	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.38017467247637415	[67]	[103]	4	hSpCas9	negative selection	10953458
157544483	157544506	2	-	28162770	P31FUJ	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.3268174481923143	[133]	[394]	9	hSpCas9	negative selection	10953459
157542773	157542796	2	-	28162770	P31FUJ	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.4178635433576071	[371]	[583]	4	hSpCas9	negative selection	10953460
157541088	157541111	2	+	28162770	P31FUJ	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.3099908420628381	[728]	[1061]	3	hSpCas9	negative selection	10953461
157544503	157544526	2	+	28162770	P31FUJ	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.6290668767221288	[114]	[208]	7	hSpCas9	negative selection	10953462
157587175	157587198	2	+	28162770	P31FUJ	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.6547230663272088	[859]	[1590]	7	hSpCas9	negative selection	10953463
157587327	157587350	2	-	28162770	OCIAML5	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.4761891439953764	[181]	[456]	4	hSpCas9	negative selection	11122820
157541131	157541154	2	-	28162770	OCIAML5	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.336137164296624	[304]	[694]	3	hSpCas9	negative selection	11122821
157538585	157538608	2	-	28162770	OCIAML5	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-0.45351719437372195	[65]	[86]	-3	hSpCas9	negative selection	11122822
157541103	157541126	2	-	28162770	OCIAML5	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-0.6821415694216846	[15]	[17]	-4	hSpCas9	negative selection	11122823
157587316	157587339	2	-	28162770	OCIAML5	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	1.570166429819051	[24]	[133]	9	hSpCas9	negative selection	11122824
157544483	157544506	2	-	28162770	OCIAML5	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.9877762039425118	[68]	[246]	8	hSpCas9	negative selection	11122825
157542773	157542796	2	-	28162770	OCIAML5	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.09362230925817905	[202]	[390]	0	hSpCas9	negative selection	11122826
157541088	157541111	2	+	28162770	OCIAML5	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.14018947580899388	[466]	[928]	1	hSpCas9	negative selection	11122827
157544503	157544526	2	+	28162770	OCIAML5	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.6776664091367671	[70]	[204]	6	hSpCas9	negative selection	11122828
157587175	157587198	2	+	28162770	OCIAML5	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.8795852234057413	[407]	[1354]	7	hSpCas9	negative selection	11122829
157587327	157587350	2	-	28162770	EOL1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.4326100869824506	[532]	[378]	4	hSpCas9	negative selection	11292186
157541131	157541154	2	-	28162770	EOL1	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.6586537115975001	[504]	[419]	6	hSpCas9	negative selection	11292187
157538585	157538608	2	-	28162770	EOL1	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-1.9411511367178744	[327]	[44]	-8	hSpCas9	negative selection	11292188
157541103	157541126	2	-	28162770	EOL1	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-0.677488242509563	[84]	[27]	-5	hSpCas9	negative selection	11292189
157587316	157587339	2	-	28162770	EOL1	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	1.1803866760001245	[133]	[159]	8	hSpCas9	negative selection	11292190
157544483	157544506	2	-	28162770	EOL1	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.9919030393722992	[271]	[284]	8	hSpCas9	negative selection	11292191
157542773	157542796	2	-	28162770	EOL1	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.04755866167587791	[381]	[207]	0	hSpCas9	negative selection	11292192
157541088	157541111	2	+	28162770	EOL1	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.14511515149865573	[677]	[394]	1	hSpCas9	negative selection	11292193
157544503	157544526	2	+	28162770	EOL1	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	1.048419429732703	[144]	[157]	8	hSpCas9	negative selection	11292194
157587175	157587198	2	+	28162770	EOL1	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.1694094313570751	[718]	[425]	1	hSpCas9	negative selection	11292195
157587327	157587350	2	-	28162770	MOLM13	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.2204518307618033	[551]	[464]	1	hSpCas9	negative selection	11461552
157541131	157541154	2	-	28162770	MOLM13	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	-0.18389122574913097	[695]	[442]	-1	hSpCas9	negative selection	11461553
157538585	157538608	2	-	28162770	MOLM13	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	0.886493495843615	[201]	[269]	6	hSpCas9	negative selection	11461554
157541103	157541126	2	-	28162770	MOLM13	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-0.06816351869563109	[57]	[39]	0	hSpCas9	negative selection	11461555
157587316	157587339	2	-	28162770	MOLM13	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.7073553162399682	[143]	[169]	5	hSpCas9	negative selection	11461556
157544483	157544506	2	-	28162770	MOLM13	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.9555546809108204	[229]	[644]	9	hSpCas9	negative selection	11461557
157542773	157542796	2	-	28162770	MOLM13	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	1.1150672787114326	[294]	[461]	8	hSpCas9	negative selection	11461558
157541088	157541111	2	+	28162770	MOLM13	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.549966894857453	[1041]	[1102]	4	hSpCas9	negative selection	11461559
157544503	157544526	2	+	28162770	MOLM13	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.26995000393267005	[194]	[169]	2	hSpCas9	negative selection	11461560
157587175	157587198	2	+	28162770	MOLM13	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.38738580845886283	[865]	[818]	3	hSpCas9	negative selection	11461561
157587327	157587350	2	-	28162770	HEL	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.6286292325849213	[410]	[406]	5	hSpCas9	negative selection	11630918
157541131	157541154	2	-	28162770	HEL	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.31444433532898275	[510]	[406]	2	hSpCas9	negative selection	11630919
157538585	157538608	2	-	28162770	HEL	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-0.494764691749578	[219]	[99]	-3	hSpCas9	negative selection	11630920
157541103	157541126	2	-	28162770	HEL	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	2.7947419254454067	[17]	[79]	9	hSpCas9	negative selection	11630921
157587316	157587339	2	-	28162770	HEL	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	1.3233664420167512	[140]	[225]	9	hSpCas9	negative selection	11630922
157544483	157544506	2	-	28162770	HEL	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.410245820694939	[214]	[365]	9	hSpCas9	negative selection	11630923
157542773	157542796	2	-	28162770	HEL	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.02054342508022572	[313]	[203]	0	hSpCas9	negative selection	11630924
157541088	157541111	2	+	28162770	HEL	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.1377316358605989	[815]	[574]	1	hSpCas9	negative selection	11630925
157544503	157544526	2	+	28162770	HEL	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.044600942531467624	[164]	[108]	0	hSpCas9	negative selection	11630926
157587175	157587198	2	+	28162770	HEL	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.7267289241433361	[733]	[777]	6	hSpCas9	negative selection	11630927
157587327	157587350	2	-	28162770	MV411	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.3025791049752362	[384]	[399]	2	hSpCas9	negative selection	11800284
157541131	157541154	2	-	28162770	MV411	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.5397925302867905	[413]	[506]	5	hSpCas9	negative selection	11800285
157538585	157538608	2	-	28162770	MV411	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	0.08765710674600619	[123]	[110]	0	hSpCas9	negative selection	11800286
157541103	157541126	2	-	28162770	MV411	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-0.6005593557721745	[44]	[24]	-4	hSpCas9	negative selection	11800287
157587316	157587339	2	-	28162770	MV411	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.3040210791491428	[74]	[77]	2	hSpCas9	negative selection	11800288
157544483	157544506	2	-	28162770	MV411	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	2.2790831773992406	[123]	[506]	9	hSpCas9	negative selection	11800289
157542773	157542796	2	-	28162770	MV411	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.4633459385490245	[222]	[258]	4	hSpCas9	negative selection	11800290
157541088	157541111	2	+	28162770	MV411	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.768176096418248	[466]	[669]	7	hSpCas9	negative selection	11800291
157544503	157544526	2	+	28162770	MV411	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.4066361456320292	[119]	[133]	3	hSpCas9	negative selection	11800292
157587175	157587198	2	+	28162770	MV411	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.3283575461663426	[519]	[549]	3	hSpCas9	negative selection	11800293
157587327	157587350	2	-	28162770	MONOMAC1	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.09394335409545018	[215]	[231]	-1	hSpCas9	negative selection	11969650
157541131	157541154	2	-	28162770	MONOMAC1	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.12113911296670121	[307]	[383]	1	hSpCas9	negative selection	11969651
157538585	157538608	2	-	28162770	MONOMAC1	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-0.43804494656334864	[103]	[87]	-4	hSpCas9	negative selection	11969652
157541103	157541126	2	-	28162770	MONOMAC1	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	1.2623947715777437	[23]	[65]	9	hSpCas9	negative selection	11969653
157587316	157587339	2	-	28162770	MONOMAC1	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.689306371144879	[32]	[60]	6	hSpCas9	negative selection	11969654
157544483	157544506	2	-	28162770	MONOMAC1	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	1.9404666766903813	[74]	[329]	9	hSpCas9	negative selection	11969655
157542773	157542796	2	-	28162770	MONOMAC1	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.2593414476001895	[128]	[176]	2	hSpCas9	negative selection	11969656
157541088	157541111	2	+	28162770	MONOMAC1	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.17352602307868525	[279]	[361]	1	hSpCas9	negative selection	11969657
157544503	157544526	2	+	28162770	MONOMAC1	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	0.10603222057649286	[76]	[94]	1	hSpCas9	negative selection	11969658
157587175	157587198	2	+	28162770	MONOMAC1	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.43884958882427494	[333]	[518]	4	hSpCas9	negative selection	11969659
157587327	157587350	2	-	28162770	OCIAML2	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	0.5227975208343525	[54]	[437]	5	hSpCas9	negative selection	12139016
157541131	157541154	2	-	28162770	OCIAML2	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	0.39878606494769453	[64]	[474]	4	hSpCas9	negative selection	12139017
157538585	157538608	2	-	28162770	OCIAML2	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-0.31682448916312583	[39]	[177]	-3	hSpCas9	negative selection	12139018
157541103	157541126	2	-	28162770	OCIAML2	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	-0.24823740390571336	[5]	[27]	-2	hSpCas9	negative selection	12139019
157587316	157587339	2	-	28162770	OCIAML2	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	0.8717623722049165	[13]	[141]	8	hSpCas9	negative selection	12139020
157544483	157544506	2	-	28162770	OCIAML2	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	0.460107512320725	[23]	[182]	4	hSpCas9	negative selection	12139021
157542773	157542796	2	-	28162770	OCIAML2	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.10763802290498692	[35]	[214]	1	hSpCas9	negative selection	12139022
157541088	157541111	2	+	28162770	OCIAML2	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.12194585958887005	[125]	[759]	1	hSpCas9	negative selection	12139023
157544503	157544526	2	+	28162770	OCIAML2	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	-0.39262731324088795	[35]	[151]	-3	hSpCas9	negative selection	12139024
157587175	157587198	2	+	28162770	OCIAML2	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.6717093445282518	[87]	[776]	6	hSpCas9	negative selection	12139025
157587327	157587350	2	-	28162770	OCIAML3	viability	GCATCAGTCATGCTAACCAATGG	ACVR1C	ENSG00000123612	-0.09477501362889096	[103]	[293]	0	hSpCas9	negative selection	12308382
157541131	157541154	2	-	28162770	OCIAML3	viability	CGAGCTGACATCTATTCTGTTGG	ACVR1C	ENSG00000123612	-0.15059928381702636	[106]	[290]	-1	hSpCas9	negative selection	12308383
157538585	157538608	2	-	28162770	OCIAML3	viability	GACCAAGTATCCCAAACCAGTGG	ACVR1C	ENSG00000123612	-0.3198326768851689	[42]	[103]	-2	hSpCas9	negative selection	12308384
157541103	157541126	2	-	28162770	OCIAML3	viability	TTTACTGGGAAATAGCCCGGAGG	ACVR1C	ENSG00000123612	0.2905151422559007	[12]	[47]	2	hSpCas9	negative selection	12308385
157587316	157587339	2	-	28162770	OCIAML3	viability	GCTAACCAATGGAAAAGAGCAGG	ACVR1C	ENSG00000123612	1.0642038424276317	[31]	[201]	8	hSpCas9	negative selection	12308386
157544483	157544506	2	-	28162770	OCIAML3	viability	CTGGCGCTCTCAATTGCTAGTGG	ACVR1C	ENSG00000123612	-0.3716152189877153	[44]	[104]	-3	hSpCas9	negative selection	12308387
157542773	157542796	2	-	28162770	OCIAML3	viability	TGCCATAGCGGACTTAGGGTTGG	ACVR1C	ENSG00000123612	0.5997641030725168	[79]	[365]	5	hSpCas9	negative selection	12308388
157541088	157541111	2	+	28162770	OCIAML3	viability	ACCTCCGACTGAACACCTCCGGG	ACVR1C	ENSG00000123612	0.055607818739246584	[159]	[501]	0	hSpCas9	negative selection	12308389
157544503	157544526	2	+	28162770	OCIAML3	viability	CAGCTTGATCATTCCAGCCACGG	ACVR1C	ENSG00000123612	-0.30310644105742535	[46]	[114]	-2	hSpCas9	negative selection	12308390
157587175	157587198	2	+	28162770	OCIAML3	viability	TAAACCCCTTACCTGTTGGAAGG	ACVR1C	ENSG00000123612	0.6080499820589584	[147]	[680]	5	hSpCas9	negative selection	12308391