Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:92
• Symbol:ACVR2A
• Description:activin A receptor type 2A

DataSource: http://genomecrispr.dkfz.de/#!/results/ACVR2A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
147896397	147896420	2	+	26472758	Jiyoye	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.17744098482825743	[196]	[167]	1	hSpCas9	negative selection	2323
147923010	147923033	2	+	26472758	Jiyoye	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	-0.20287810017811325	[57]	[37]	-1	hSpCas9	negative selection	2324
147923044	147923067	2	+	26472758	Jiyoye	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.32887038600608376	[264]	[250]	2	hSpCas9	negative selection	2325
147915206	147915229	2	-	26472758	Jiyoye	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	1.0968352608937226	[61]	[99]	7	hSpCas9	negative selection	2326
147917275	147917298	2	+	26472758	Jiyoye	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.5215080569848682	[96]	[104]	4	hSpCas9	negative selection	2327
147918497	147918520	2	+	26472758	Jiyoye	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	-0.11477732168948242	[111]	[77]	-1	hSpCas9	negative selection	2328
147918546	147918569	2	+	26472758	Jiyoye	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	-1.9385994553358568	[121]	[23]	-8	hSpCas9	negative selection	2329
147920318	147920341	2	+	26472758	Jiyoye	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	1.966602790119892	[18]	[55]	8	hSpCas9	negative selection	2330
147896397	147896420	2	+	26472758	KBM7	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	-0.24264121615248344	[740,556]	[303,211]	-2	hSpCas9	negative selection	193441
147923010	147923033	2	+	26472758	KBM7	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	0.40885997056608314	[140,142]	[95,82]	4	hSpCas9	negative selection	193442
147923044	147923067	2	+	26472758	KBM7	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	-0.03672519689316622	[1229,745]	[514,379]	0	hSpCas9	negative selection	193443
147915206	147915229	2	-	26472758	KBM7	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	1.7416352474489594	[200,179]	[302,295]	9	hSpCas9	negative selection	193444
147917275	147917298	2	+	26472758	KBM7	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.48815776668639094	[533,420]	[243,373]	5	hSpCas9	negative selection	193445
147918497	147918520	2	+	26472758	KBM7	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	-0.042941316176091204	[708,697]	[267,370]	0	hSpCas9	negative selection	193446
147918546	147918569	2	+	26472758	KBM7	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	0.04228786251348726	[190,222]	[91,109]	0	hSpCas9	negative selection	193447
147920318	147920341	2	+	26472758	KBM7	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	-0.19910042000294265	[387,362]	[96,204]	-2	hSpCas9	negative selection	193448
147896397	147896420	2	+	26472758	Raji	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.24065006623706364	[309]	[84]	2	hSpCas9	negative selection	384559
147923010	147923033	2	+	26472758	Raji	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	-0.16825090723982772	[91]	[18]	-1	hSpCas9	negative selection	384560
147923044	147923067	2	+	26472758	Raji	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.9626484423925888	[439]	[198]	8	hSpCas9	negative selection	384561
147915206	147915229	2	-	26472758	Raji	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	-0.4141535852059232	[177]	[30]	-3	hSpCas9	negative selection	384562
147917275	147917298	2	+	26472758	Raji	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.5096537385785653	[226]	[74]	5	hSpCas9	negative selection	384563
147918497	147918520	2	+	26472758	Raji	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.2933955209835484	[326]	[92]	2	hSpCas9	negative selection	384564
147918546	147918569	2	+	26472758	Raji	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	1.3553110488171851	[63]	[37]	9	hSpCas9	negative selection	384565
147920318	147920341	2	+	26472758	Raji	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	-0.14559720579627144	[142]	[29]	-1	hSpCas9	negative selection	384566
147896397	147896420	2	+	26472758	K562	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.8733661216704669	[462]	[715]	7	hSpCas9	negative selection	575677
147923010	147923033	2	+	26472758	K562	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	0.20289945822818	[140]	[136]	1	hSpCas9	negative selection	575678
147923044	147923067	2	+	26472758	K562	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.7515277551303559	[716]	[1018]	6	hSpCas9	negative selection	575679
147915206	147915229	2	-	26472758	K562	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	0.46045565396307153	[389]	[452]	3	hSpCas9	negative selection	575680
147917275	147917298	2	+	26472758	K562	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	1.265548894430463	[304]	[618]	9	hSpCas9	negative selection	575681
147918497	147918520	2	+	26472758	K562	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	-0.24282681394684608	[634]	[452]	-2	hSpCas9	negative selection	575682
147918546	147918569	2	+	26472758	K562	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	1.9606257616658558	[139]	[459]	9	hSpCas9	negative selection	575683
147920318	147920341	2	+	26472758	K562	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	1.066326405352736	[154]	[273]	8	hSpCas9	negative selection	575684
147845196	147845219	2	-	26627737	DLD1	viability	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.6457806961254848	[1023]	[395,596,511]	6	hSpCas9	negative selection	808790
147918514	147918537	2	-	26627737	DLD1	viability	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.46275272792696537	[601]	[189,73,141]	-5	hSpCas9	negative selection	808791
147920323	147920346	2	+	26627737	DLD1	viability	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.1692907303324226	[822]	[284,159,236]	-2	hSpCas9	negative selection	808792
147922981	147923004	2	+	26627737	DLD1	viability	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.673648026280973	[458]	[183,329,183]	6	hSpCas9	negative selection	808793
147927117	147927140	2	+	26627737	DLD1	viability	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	-0.5108146893760244	[264]	[69,63,42]	-5	hSpCas9	negative selection	808794
147845196	147845219	2	-	26627737	GBM cells	viability after 5 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.3788420366548739	[787]	[346,302]	-5	hSpCas9	negative selection	891105
147918514	147918537	2	-	26627737	GBM cells	viability after 5 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.005327142308883592	[305]	[170,155]	0	hSpCas9	negative selection	891106
147920323	147920346	2	+	26627737	GBM cells	viability after 5 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.41166924640766756	[474]	[229,152]	-6	hSpCas9	negative selection	891107
147922981	147923004	2	+	26627737	GBM cells	viability after 5 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.3123551679790518	[322]	[153,124]	-5	hSpCas9	negative selection	891108
147927117	147927140	2	+	26627737	GBM cells	viability after 5 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.4361796335755457	[163]	[102,134]	6	hSpCas9	negative selection	891109
147845196	147845219	2	-	26627737	GBM cells	viability after 13 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.09196392988395963	[787]	[533,391]	1	hSpCas9	negative selection	973420
147918514	147918537	2	-	26627737	GBM cells	viability after 13 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.41975220575937777	[305]	[204,235]	5	hSpCas9	negative selection	973421
147920323	147920346	2	+	26627737	GBM cells	viability after 13 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.8253156800276729	[474]	[145,144]	-7	hSpCas9	negative selection	973422
147922981	147923004	2	+	26627737	GBM cells	viability after 13 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.4856371363703017	[322]	[101,143]	-5	hSpCas9	negative selection	973423
147927117	147927140	2	+	26627737	GBM cells	viability after 13 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.005044353125490786	[163]	[128,56]	0	hSpCas9	negative selection	973424
147845196	147845219	2	-	26627737	GBM cells	viability after 21 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.000696773585971977	[787]	[420,434]	0	hSpCas9	negative selection	1055735
147918514	147918537	2	-	26627737	GBM cells	viability after 21 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.11694065630557796	[305]	[157,148]	-1	hSpCas9	negative selection	1055736
147920323	147920346	2	+	26627737	GBM cells	viability after 21 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.9425930312043858	[474]	[127,139]	-7	hSpCas9	negative selection	1055737
147922981	147923004	2	+	26627737	GBM cells	viability after 21 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.5343080018798283	[322]	[128,113]	-5	hSpCas9	negative selection	1055738
147927117	147927140	2	+	26627737	GBM cells	viability after 21 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.11330992653100325	[163]	[110,82]	1	hSpCas9	negative selection	1055739
147845196	147845219	2	-	26627737	RPE1	viability after 9 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.8630749374592621	[1411]	[831,767]	5	hSpCas9	negative selection	1138050
147918514	147918537	2	-	26627737	RPE1	viability after 9 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.5053748091489102	[553]	[157,359]	3	hSpCas9	negative selection	1138051
147920323	147920346	2	+	26627737	RPE1	viability after 9 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	1.1193784005043719	[745]	[454,574]	6	hSpCas9	negative selection	1138052
147922981	147923004	2	+	26627737	RPE1	viability after 9 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-1.3997046786318386	[1589]	[144,244]	-7	hSpCas9	negative selection	1138053
147927117	147927140	2	+	26627737	RPE1	viability after 9 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.6536026651114949	[537]	[274,251]	4	hSpCas9	negative selection	1138054
147845196	147845219	2	-	26627737	RPE1	viability after 12 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.9502001909809519	[1411]	[646,823]	6	hSpCas9	negative selection	1220365
147918514	147918537	2	-	26627737	RPE1	viability after 12 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.7918379939371578	[553]	[127,394]	5	hSpCas9	negative selection	1220366
147920323	147920346	2	+	26627737	RPE1	viability after 12 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	1.5087652260769557	[745]	[309,845]	8	hSpCas9	negative selection	1220367
147922981	147923004	2	+	26627737	RPE1	viability after 12 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-1.2699301552819464	[1589]	[147,207]	-7	hSpCas9	negative selection	1220368
147927117	147927140	2	+	26627737	RPE1	viability after 12 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.9208747524075482	[537]	[295,249]	6	hSpCas9	negative selection	1220369
147845196	147845219	2	-	26627737	RPE1	viability after 15 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	1.0234760011111184	[1411]	[898,727]	6	hSpCas9	negative selection	1302680
147918514	147918537	2	-	26627737	RPE1	viability after 15 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	1.1295670335009522	[553]	[208,471]	6	hSpCas9	negative selection	1302681
147920323	147920346	2	+	26627737	RPE1	viability after 15 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	1.823030284072227	[745]	[849,646]	8	hSpCas9	negative selection	1302682
147922981	147923004	2	+	26627737	RPE1	viability after 15 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-1.3220797468890841	[1589]	[185,173]	-7	hSpCas9	negative selection	1302683
147927117	147927140	2	+	26627737	RPE1	viability after 15 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.462883536619097	[537]	[166,250]	3	hSpCas9	negative selection	1302684
147845196	147845219	2	-	26627737	RPE1	viability after 18 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.76833443860248	[1411]	[635,662]	5	hSpCas9	negative selection	1384995
147918514	147918537	2	-	26627737	RPE1	viability after 18 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.49332639546217644	[553]	[150,273]	3	hSpCas9	negative selection	1384996
147920323	147920346	2	+	26627737	RPE1	viability after 18 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	1.9033604037093341	[745]	[566,951]	8	hSpCas9	negative selection	1384997
147922981	147923004	2	+	26627737	RPE1	viability after 18 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-1.0197078769316055	[1589]	[200,222]	-6	hSpCas9	negative selection	1384998
147927117	147927140	2	+	26627737	RPE1	viability after 18 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.5385595827817337	[537]	[265,151]	3	hSpCas9	negative selection	1384999
147845196	147845219	2	-	26627737	HeLa	viability after 8 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.11444528738503879	[1193]	[622,393,455]	-1	hSpCas9	negative selection	1467310
147918514	147918537	2	-	26627737	HeLa	viability after 8 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.9648393362998441	[306]	[397,176,238]	7	hSpCas9	negative selection	1467311
147920323	147920346	2	+	26627737	HeLa	viability after 8 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	0.03229955369833615	[920]	[465,382,393]	0	hSpCas9	negative selection	1467312
147922981	147923004	2	+	26627737	HeLa	viability after 8 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.004548794916993698	[453]	[339,209,83]	0	hSpCas9	negative selection	1467313
147927117	147927140	2	+	26627737	HeLa	viability after 8 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.012161673724275457	[209]	[17,147,93]	0	hSpCas9	negative selection	1467314
147845196	147845219	2	-	26627737	HeLa	viability after 12 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.2748537121445316	[1193]	[706,494,602]	2	hSpCas9	negative selection	1549625
147918514	147918537	2	-	26627737	HeLa	viability after 12 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.8402441166685901	[306]	[205,149,332]	6	hSpCas9	negative selection	1549626
147920323	147920346	2	+	26627737	HeLa	viability after 12 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.39262452758226096	[920]	[38,322,496]	-3	hSpCas9	negative selection	1549627
147922981	147923004	2	+	26627737	HeLa	viability after 12 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.3011119205535915	[453]	[159,133,164]	-3	hSpCas9	negative selection	1549628
147927117	147927140	2	+	26627737	HeLa	viability after 12 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.824123680629929	[209]	[128,136,195]	6	hSpCas9	negative selection	1549629
147845196	147845219	2	-	26627737	HeLa	viability after 15 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.24854227666896778	[1193]	[297,423,514]	-2	hSpCas9	negative selection	1631940
147918514	147918537	2	-	26627737	HeLa	viability after 15 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.8198683920235017	[306]	[267,66,334]	6	hSpCas9	negative selection	1631941
147920323	147920346	2	+	26627737	HeLa	viability after 15 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	0.20432895508518567	[920]	[389,371,542]	1	hSpCas9	negative selection	1631942
147922981	147923004	2	+	26627737	HeLa	viability after 15 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.6940131135549716	[453]	[395,209,288]	5	hSpCas9	negative selection	1631943
147927117	147927140	2	+	26627737	HeLa	viability after 15 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.6637639341800499	[209]	[155,90,160]	5	hSpCas9	negative selection	1631944
147845196	147845219	2	-	26627737	HeLa	viability after 18 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.2373732821183907	[1193]	[202,354,514]	-2	hSpCas9	negative selection	1714255
147918514	147918537	2	-	26627737	HeLa	viability after 18 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.7981855877593667	[306]	[168,60,334]	6	hSpCas9	negative selection	1714256
147920323	147920346	2	+	26627737	HeLa	viability after 18 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	0.22428195336710632	[920]	[266,315,542]	2	hSpCas9	negative selection	1714257
147922981	147923004	2	+	26627737	HeLa	viability after 18 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.7083005687407018	[453]	[268,176,288]	5	hSpCas9	negative selection	1714258
147927117	147927140	2	+	26627737	HeLa	viability after 18 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.6541417685950006	[209]	[103,73,160]	5	hSpCas9	negative selection	1714259
147845196	147845219	2	-	26627737	HCT116	viability after 6 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.4040411352433475	[2119]	[354,194]	-2	hSpCas9	negative selection	1796570
147918514	147918537	2	-	26627737	HCT116	viability after 6 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-2.1118305941959257	[800]	[32,26]	-8	hSpCas9	negative selection	1796571
147920323	147920346	2	+	26627737	HCT116	viability after 6 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.9407904491978085	[1555]	[207,82]	-5	hSpCas9	negative selection	1796572
147922981	147923004	2	+	26627737	HCT116	viability after 6 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.4995550369853907	[812]	[72,99]	-3	hSpCas9	negative selection	1796573
147927117	147927140	2	+	26627737	HCT116	viability after 6 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	1.1911990064026745	[244]	[134,61]	6	hSpCas9	negative selection	1796574
147845196	147845219	2	-	26627737	HCT116	viability after 8 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.014524739271944975	[731]	[439,304,452]	0	hSpCas9	negative selection	1878885
147918514	147918537	2	-	26627737	HCT116	viability after 8 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.7630029775780819	[264]	[229,257,254]	7	hSpCas9	negative selection	1878886
147920323	147920346	2	+	26627737	HCT116	viability after 8 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.43104184876442153	[759]	[338,334,258]	-5	hSpCas9	negative selection	1878887
147922981	147923004	2	+	26627737	HCT116	viability after 8 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.11381664688987739	[256]	[130,79,180]	-1	hSpCas9	negative selection	1878888
147927117	147927140	2	+	26627737	HCT116	viability after 8 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	2.936732798741598	[37]	[187,176,116]	9	hSpCas9	negative selection	1878889
147845196	147845219	2	-	26627737	HCT116	viability after 9 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.45526993918552394	[2119]	[351,460]	-3	hSpCas9	negative selection	1961200
147918514	147918537	2	-	26627737	HCT116	viability after 9 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.6152181405242634	[800]	[583,124]	4	hSpCas9	negative selection	1961201
147920323	147920346	2	+	26627737	HCT116	viability after 9 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.5245205957973932	[1555]	[70,460]	-4	hSpCas9	negative selection	1961202
147922981	147923004	2	+	26627737	HCT116	viability after 9 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.4180114324538612	[812]	[508,116]	3	hSpCas9	negative selection	1961203
147927117	147927140	2	+	26627737	HCT116	viability after 9 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.7570187735037256	[244]	[233,12]	5	hSpCas9	negative selection	1961204
147845196	147845219	2	-	26627737	HCT116	viability after 12 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.24091920197294736	[731]	[345,334,293]	-3	hSpCas9	negative selection	2043515
147918514	147918537	2	-	26627737	HCT116	viability after 12 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.6191560346520233	[264]	[219,164,254]	6	hSpCas9	negative selection	2043516
147920323	147920346	2	+	26627737	HCT116	viability after 12 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.7207822295471344	[759]	[163,410,162]	-7	hSpCas9	negative selection	2043517
147922981	147923004	2	+	26627737	HCT116	viability after 12 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.022178079985526594	[256]	[120,100,189]	0	hSpCas9	negative selection	2043518
147927117	147927140	2	+	26627737	HCT116	viability after 12 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	3.258849720840133	[37]	[231,195,141]	9	hSpCas9	negative selection	2043519
147845196	147845219	2	-	26627737	HCT116	viability after 15 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.24044552146947695	[731]	[673,385,451]	2	hSpCas9	negative selection	2125830
147918514	147918537	2	-	26627737	HCT116	viability after 15 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.6421859508141418	[264]	[234,218,257]	6	hSpCas9	negative selection	2125831
147920323	147920346	2	+	26627737	HCT116	viability after 15 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.45869672025780217	[759]	[404,289,268]	-5	hSpCas9	negative selection	2125832
147922981	147923004	2	+	26627737	HCT116	viability after 15 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.4709209807277501	[256]	[141,169,292]	4	hSpCas9	negative selection	2125833
147927117	147927140	2	+	26627737	HCT116	viability after 15 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	3.005054420358948	[37]	[316,145,80]	9	hSpCas9	negative selection	2125834
147845196	147845219	2	-	26627737	HCT116	viability after 18 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.04331186411514887	[731]	[315,296,423]	0	hSpCas9	negative selection	2208145
147918514	147918537	2	-	26627737	HCT116	viability after 18 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.4284634302050841	[264]	[264,127,124]	3	hSpCas9	negative selection	2208146
147920323	147920346	2	+	26627737	HCT116	viability after 18 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.1726521924899278	[759]	[368,461,128]	-1	hSpCas9	negative selection	2208147
147922981	147923004	2	+	26627737	HCT116	viability after 18 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.06257581871654536	[256]	[140,74,144]	0	hSpCas9	negative selection	2208148
147927117	147927140	2	+	26627737	HCT116	viability after 18 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	3.2003370335216252	[37]	[208,165,129]	9	hSpCas9	negative selection	2208149
147845152	147845175	2	+	24336569	HL60	viability	AATGGGAGCTGCTGCAAAGTTGG	ACVR2A	ENSG00000121989	0.21015416010120713	[961]	[2354]	2	hSpCas9	negative selection	2246553
147845181	147845204	2	-	24336569	HL60	viability	AGAACAGGAGATAAGAAAGACGG	ACVR2A	ENSG00000121989	-0.7740965502698564	[955]	[1182]	-6	hSpCas9	negative selection	2246554
147845186	147845209	2	+	24336569	HL60	viability	TTTCTTATCTCCTGTTCTTCAGG	ACVR2A	ENSG00000121989	-0.021091482649414517	[350]	[731]	0	hSpCas9	negative selection	2246555
147845196	147845219	2	-	24336569	HL60	viability	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.36485244033574304	[1084]	[1782]	-3	hSpCas9	negative selection	2246556
147896291	147896314	2	+	24336569	HL60	viability	TATCTTATAGGTGCTATACTTGG	ACVR2A	ENSG00000121989	1.4160355588419202	[169]	[959]	8	hSpCas9	negative selection	2246557
147896370	147896393	2	-	24336569	HL60	viability	CGGTTCAACACCAGTTTGATTGG	ACVR2A	ENSG00000121989	-0.169494864982617	[396]	[746]	-1	hSpCas9	negative selection	2246558
147896378	147896401	2	+	24336569	HL60	viability	ACTGGTGTTGAACCGTGTTATGG	ACVR2A	ENSG00000121989	0.08623623569890221	[648]	[1457]	0	hSpCas9	negative selection	2246559
147896390	147896413	2	-	24336569	HL60	viability	TTATCTTTGTCACCATAACACGG	ACVR2A	ENSG00000121989	-0.26851190660020136	[587]	[1032]	-2	hSpCas9	negative selection	2246560
147896397	147896420	2	+	24336569	HL60	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	-2.1150600699004998	[390]	[190]	-9	hSpCas9	negative selection	2246561
147896429	147896452	2	+	24336569	HL60	viability	GCTACCTGGAAGAATATTTCTGG	ACVR2A	ENSG00000121989	0.09607408492329128	[1091]	[2469]	0	hSpCas9	negative selection	2246562
147845152	147845175	2	+	24336569	KBM7	viability	AATGGGAGCTGCTGCAAAGTTGG	ACVR2A	ENSG00000121989	1.5217432051721145	[403]	[3163]	9	hSpCas9	negative selection	2313730
147845181	147845204	2	-	24336569	KBM7	viability	AGAACAGGAGATAAGAAAGACGG	ACVR2A	ENSG00000121989	-0.4437337165975876	[561]	[1126]	-4	hSpCas9	negative selection	2313731
147845186	147845209	2	+	24336569	KBM7	viability	TTTCTTATCTCCTGTTCTTCAGG	ACVR2A	ENSG00000121989	1.2751925160345694	[142]	[943]	9	hSpCas9	negative selection	2313732
147845196	147845219	2	-	24336569	KBM7	viability	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.5324461036898513	[799]	[3155]	5	hSpCas9	negative selection	2313733
147896291	147896314	2	+	24336569	KBM7	viability	TATCTTATAGGTGCTATACTTGG	ACVR2A	ENSG00000121989	0.5181064389257828	[350]	[1370]	5	hSpCas9	negative selection	2313734
147896370	147896393	2	-	24336569	KBM7	viability	CGGTTCAACACCAGTTTGATTGG	ACVR2A	ENSG00000121989	1.0923781581472434	[368]	[2145]	8	hSpCas9	negative selection	2313735
147896378	147896401	2	+	24336569	KBM7	viability	ACTGGTGTTGAACCGTGTTATGG	ACVR2A	ENSG00000121989	1.5310879338279986	[263]	[2080]	9	hSpCas9	negative selection	2313736
147896390	147896413	2	-	24336569	KBM7	viability	TTATCTTTGTCACCATAACACGG	ACVR2A	ENSG00000121989	0.5210403888113422	[243]	[954]	5	hSpCas9	negative selection	2313737
147896397	147896420	2	+	24336569	KBM7	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	1.1572828616099788	[95]	[583]	8	hSpCas9	negative selection	2313738
147896429	147896452	2	+	24336569	KBM7	viability	GCTACCTGGAAGAATATTTCTGG	ACVR2A	ENSG00000121989	0.03137359909979831	[1020]	[2845]	0	hSpCas9	negative selection	2313739
147844860	147844883	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAACCCGCTTTTGTTGTTGTTGG	ACVR2A	ENSG00000121989	-2.4369465769890226	[257,384]	[9,14]	-9	dCas9-VP64	positive selection	2428183
147844875	147844898	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTGTTGGCTTTTCGTTGTTTGG	ACVR2A	ENSG00000121989	-2.210918411519052	[356,1313]	[10,70]	-9	dCas9-VP64	positive selection	2428184
147844797	147844820	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCGTTTTGTTCCGAGAGACGG	ACVR2A	ENSG00000121989	4.02669245380883	[99,24]	[422,8]	9	dCas9-VP64	positive selection	2428185
147868662	147868685	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCAGCCTGGGCTACAGAAGG	ACVR2A	ENSG00000121989	-0.9551243910692007	[6,111]	[7,3]	-5	dCas9-VP64	positive selection	2459181
147844860	147844883	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAACCCGCTTTTGTTGTTGTTGG	ACVR2A	ENSG00000121989	1.7126591069326897	[137,241]	[155,245]	8	dCas9-VP64	positive selection	2523438
147844875	147844898	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTGTTGGCTTTTCGTTGTTTGG	ACVR2A	ENSG00000121989	3.043136802119564	[266,294]	[200,1279]	9	dCas9-VP64	positive selection	2523439
147844797	147844820	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCGTTTTGTTCCGAGAGACGG	ACVR2A	ENSG00000121989	0.6430828799702852	[287,265]	[57,218]	5	dCas9-VP64	positive selection	2523440
147868662	147868685	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCAGCCTGGGCTACAGAAGG	ACVR2A	ENSG00000121989	-0.22071864971822522	[77,140]	[18,40]	-2	dCas9-VP64	positive selection	2554436
147896429	147896452	2	+	27260157	DLD1	viability	GCTACCTGGAAGAATATTTCTGG	ACVR2A	ENSG00000121989	0.645801911902417	[]	[]	8	hSpCas9	negative selection	2579006
147917307	147917330	2	+	27260157	DLD1	viability	TACGAAGTCTACAGTTTGCCTGG	ACVR2A	ENSG00000121989	0.0142330927985991	[]	[]	0	hSpCas9	negative selection	2579248
147896378	147896401	2	+	27260157	DLD1	viability	ACTGGTGTTGAACCGTGTTATGG	ACVR2A	ENSG00000121989	-0.0859326639984653	[]	[]	0	hSpCas9	negative selection	2605632
147896291	147896314	2	+	27260157	DLD1	viability	TATCTTATAGGTGCTATACTTGG	ACVR2A	ENSG00000121989	0.0501539442196807	[]	[]	3	hSpCas9	negative selection	2606708
147896397	147896420	2	+	27260157	DLD1	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	-0.2035892209523	[]	[]	-1	hSpCas9	negative selection	2606994
147896390	147896413	2	-	27260157	DLD1	viability	TTATCTTTGTCACCATAACACGG	ACVR2A	ENSG00000121989	0.925368598059053	[]	[]	9	hSpCas9	negative selection	2608178
147845181	147845204	2	-	27260157	DLD1	viability	AGAACAGGAGATAAGAAAGACGG	ACVR2A	ENSG00000121989	-0.490007917007723	[]	[]	-4	hSpCas9	negative selection	2609411
147845152	147845175	2	+	27260157	DLD1	viability	AATGGGAGCTGCTGCAAAGTTGG	ACVR2A	ENSG00000121989	0.173347076171841	[]	[]	3	hSpCas9	negative selection	2612615
147845196	147845219	2	-	27260157	DLD1	viability	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.0202517464922811	[]	[]	0	hSpCas9	negative selection	2619577
147896464	147896487	2	+	27260157	DLD1	viability	AGTGAAACAAGGTTGTTGGCTGG	ACVR2A	ENSG00000121989	0.148504953911812	[]	[]	3	hSpCas9	negative selection	2620401
147896370	147896393	2	-	27260157	DLD1	viability	CGGTTCAACACCAGTTTGATTGG	ACVR2A	ENSG00000121989	-0.188781380706936	[]	[]	-1	hSpCas9	negative selection	2621028
147915203	147915226	2	-	27260157	DLD1	viability	CCTAGTAATGGAGAAGGTGGGGG	ACVR2A	ENSG00000121989	0.476912969395726	[]	[]	8	hSpCas9	negative selection	2622385
147845186	147845209	2	+	27260157	DLD1	viability	TTTCTTATCTCCTGTTCTTCAGG	ACVR2A	ENSG00000121989	0.0475303017805482	[]	[]	3	hSpCas9	negative selection	2643818
147896429	147896452	2	+	27260157	HT1080	viability	GCTACCTGGAAGAATATTTCTGG	ACVR2A	ENSG00000121989	-0.00370136342642565	[]	[]	0	hSpCas9	negative selection	2655136
147917307	147917330	2	+	27260157	HT1080	viability	TACGAAGTCTACAGTTTGCCTGG	ACVR2A	ENSG00000121989	1.12992738244299	[]	[]	8	hSpCas9	negative selection	2655378
147896378	147896401	2	+	27260157	HT1080	viability	ACTGGTGTTGAACCGTGTTATGG	ACVR2A	ENSG00000121989	0.195287787013018	[]	[]	1	hSpCas9	negative selection	2681762
147896291	147896314	2	+	27260157	HT1080	viability	TATCTTATAGGTGCTATACTTGG	ACVR2A	ENSG00000121989	0.971139771258557	[]	[]	7	hSpCas9	negative selection	2682838
147896397	147896420	2	+	27260157	HT1080	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	-0.870606678340941	[]	[]	-8	hSpCas9	negative selection	2683124
147896390	147896413	2	-	27260157	HT1080	viability	TTATCTTTGTCACCATAACACGG	ACVR2A	ENSG00000121989	0.506712860450412	[]	[]	4	hSpCas9	negative selection	2684308
147845181	147845204	2	-	27260157	HT1080	viability	AGAACAGGAGATAAGAAAGACGG	ACVR2A	ENSG00000121989	-0.0759765813138754	[]	[]	0	hSpCas9	negative selection	2685541
147845152	147845175	2	+	27260157	HT1080	viability	AATGGGAGCTGCTGCAAAGTTGG	ACVR2A	ENSG00000121989	0.54361726650311	[]	[]	5	hSpCas9	negative selection	2688745
147845196	147845219	2	-	27260157	HT1080	viability	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.738544578770016	[]	[]	6	hSpCas9	negative selection	2695707
147896464	147896487	2	+	27260157	HT1080	viability	AGTGAAACAAGGTTGTTGGCTGG	ACVR2A	ENSG00000121989	-0.094352640645459	[]	[]	0	hSpCas9	negative selection	2696531
147896370	147896393	2	-	27260157	HT1080	viability	CGGTTCAACACCAGTTTGATTGG	ACVR2A	ENSG00000121989	0.155270638465863	[]	[]	1	hSpCas9	negative selection	2697158
147915203	147915226	2	-	27260157	HT1080	viability	CCTAGTAATGGAGAAGGTGGGGG	ACVR2A	ENSG00000121989	0.194068289350344	[]	[]	1	hSpCas9	negative selection	2698515
147845186	147845209	2	+	27260157	HT1080	viability	TTTCTTATCTCCTGTTCTTCAGG	ACVR2A	ENSG00000121989	-0.0746983981473706	[]	[]	0	hSpCas9	negative selection	2719948
147896429	147896452	2	+	27260157	MKN45	viability	GCTACCTGGAAGAATATTTCTGG	ACVR2A	ENSG00000121989	0.497094507203367	[]	[]	6	hSpCas9	negative selection	2731266
147917307	147917330	2	+	27260157	MKN45	viability	TACGAAGTCTACAGTTTGCCTGG	ACVR2A	ENSG00000121989	0.928861615471058	[]	[]	8	hSpCas9	negative selection	2731508
147896378	147896401	2	+	27260157	MKN45	viability	ACTGGTGTTGAACCGTGTTATGG	ACVR2A	ENSG00000121989	0.35141742934881	[]	[]	6	hSpCas9	negative selection	2757892
147896291	147896314	2	+	27260157	MKN45	viability	TATCTTATAGGTGCTATACTTGG	ACVR2A	ENSG00000121989	0.341281352335048	[]	[]	6	hSpCas9	negative selection	2758968
147896397	147896420	2	+	27260157	MKN45	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	-1.34099671221782	[]	[]	-8	hSpCas9	negative selection	2759254
147896390	147896413	2	-	27260157	MKN45	viability	TTATCTTTGTCACCATAACACGG	ACVR2A	ENSG00000121989	1.27749324020119	[]	[]	9	hSpCas9	negative selection	2760438
147845181	147845204	2	-	27260157	MKN45	viability	AGAACAGGAGATAAGAAAGACGG	ACVR2A	ENSG00000121989	-0.256930401372907	[]	[]	-1	hSpCas9	negative selection	2761671
147845152	147845175	2	+	27260157	MKN45	viability	AATGGGAGCTGCTGCAAAGTTGG	ACVR2A	ENSG00000121989	1.06497077671325	[]	[]	8	hSpCas9	negative selection	2764875
147845196	147845219	2	-	27260157	MKN45	viability	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.571355314509995	[]	[]	7	hSpCas9	negative selection	2771837
147896464	147896487	2	+	27260157	MKN45	viability	AGTGAAACAAGGTTGTTGGCTGG	ACVR2A	ENSG00000121989	-0.744365309896697	[]	[]	-7	hSpCas9	negative selection	2772661
147896370	147896393	2	-	27260157	MKN45	viability	CGGTTCAACACCAGTTTGATTGG	ACVR2A	ENSG00000121989	-0.644485252081554	[]	[]	-7	hSpCas9	negative selection	2773288
147915203	147915226	2	-	27260157	MKN45	viability	CCTAGTAATGGAGAAGGTGGGGG	ACVR2A	ENSG00000121989	0.201575273536893	[]	[]	5	hSpCas9	negative selection	2774645
147845186	147845209	2	+	27260157	MKN45	viability	TTTCTTATCTCCTGTTCTTCAGG	ACVR2A	ENSG00000121989	-0.147760197959033	[]	[]	0	hSpCas9	negative selection	2796078
147896429	147896452	2	+	27260157	RKO	viability	GCTACCTGGAAGAATATTTCTGG	ACVR2A	ENSG00000121989	-0.0138513925275311	[]	[]	0	hSpCas9	negative selection	2807396
147917307	147917330	2	+	27260157	RKO	viability	TACGAAGTCTACAGTTTGCCTGG	ACVR2A	ENSG00000121989	1.46565764212287	[]	[]	9	hSpCas9	negative selection	2807638
147896378	147896401	2	+	27260157	RKO	viability	ACTGGTGTTGAACCGTGTTATGG	ACVR2A	ENSG00000121989	-0.0372608603126154	[]	[]	0	hSpCas9	negative selection	2834022
147896291	147896314	2	+	27260157	RKO	viability	TATCTTATAGGTGCTATACTTGG	ACVR2A	ENSG00000121989	0.435427453435933	[]	[]	2	hSpCas9	negative selection	2835098
147896397	147896420	2	+	27260157	RKO	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	-0.952068652213603	[]	[]	-8	hSpCas9	negative selection	2835384
147896390	147896413	2	-	27260157	RKO	viability	TTATCTTTGTCACCATAACACGG	ACVR2A	ENSG00000121989	0.293405429376065	[]	[]	1	hSpCas9	negative selection	2836568
147845181	147845204	2	-	27260157	RKO	viability	AGAACAGGAGATAAGAAAGACGG	ACVR2A	ENSG00000121989	0.180901750013158	[]	[]	1	hSpCas9	negative selection	2837801
147845152	147845175	2	+	27260157	RKO	viability	AATGGGAGCTGCTGCAAAGTTGG	ACVR2A	ENSG00000121989	0.480785506961683	[]	[]	2	hSpCas9	negative selection	2841005
147845196	147845219	2	-	27260157	RKO	viability	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.198382018580235	[]	[]	1	hSpCas9	negative selection	2847967
147896464	147896487	2	+	27260157	RKO	viability	AGTGAAACAAGGTTGTTGGCTGG	ACVR2A	ENSG00000121989	-0.433720158953739	[]	[]	-6	hSpCas9	negative selection	2848791
147896370	147896393	2	-	27260157	RKO	viability	CGGTTCAACACCAGTTTGATTGG	ACVR2A	ENSG00000121989	-0.539750592959971	[]	[]	-7	hSpCas9	negative selection	2849418
147915203	147915226	2	-	27260157	RKO	viability	CCTAGTAATGGAGAAGGTGGGGG	ACVR2A	ENSG00000121989	-0.0482352671298752	[]	[]	0	hSpCas9	negative selection	2850775
147845186	147845209	2	+	27260157	RKO	viability	TTTCTTATCTCCTGTTCTTCAGG	ACVR2A	ENSG00000121989	-0.307664025988324	[]	[]	-6	hSpCas9	negative selection	2872208
147896429	147896452	2	+	27260157	SF268	viability	GCTACCTGGAAGAATATTTCTGG	ACVR2A	ENSG00000121989	1.009007912832	[]	[]	9	hSpCas9	negative selection	2883526
147917307	147917330	2	+	27260157	SF268	viability	TACGAAGTCTACAGTTTGCCTGG	ACVR2A	ENSG00000121989	0.859129089893972	[]	[]	9	hSpCas9	negative selection	2883768
147896378	147896401	2	+	27260157	SF268	viability	ACTGGTGTTGAACCGTGTTATGG	ACVR2A	ENSG00000121989	-0.121478826433678	[]	[]	-1	hSpCas9	negative selection	2910152
147896291	147896314	2	+	27260157	SF268	viability	TATCTTATAGGTGCTATACTTGG	ACVR2A	ENSG00000121989	-0.106361937965139	[]	[]	-1	hSpCas9	negative selection	2911228
147896397	147896420	2	+	27260157	SF268	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	-0.959094246319573	[]	[]	-6	hSpCas9	negative selection	2911514
147896390	147896413	2	-	27260157	SF268	viability	TTATCTTTGTCACCATAACACGG	ACVR2A	ENSG00000121989	0.588117882374546	[]	[]	8	hSpCas9	negative selection	2912698
147845181	147845204	2	-	27260157	SF268	viability	AGAACAGGAGATAAGAAAGACGG	ACVR2A	ENSG00000121989	0.284953444203994	[]	[]	4	hSpCas9	negative selection	2913931
147845152	147845175	2	+	27260157	SF268	viability	AATGGGAGCTGCTGCAAAGTTGG	ACVR2A	ENSG00000121989	0.784053210679591	[]	[]	8	hSpCas9	negative selection	2917135
147845196	147845219	2	-	27260157	SF268	viability	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.256280752826265	[]	[]	4	hSpCas9	negative selection	2924097
147896464	147896487	2	+	27260157	SF268	viability	AGTGAAACAAGGTTGTTGGCTGG	ACVR2A	ENSG00000121989	-0.718216652482071	[]	[]	-5	hSpCas9	negative selection	2924921
147896370	147896393	2	-	27260157	SF268	viability	CGGTTCAACACCAGTTTGATTGG	ACVR2A	ENSG00000121989	-0.098434370943385	[]	[]	-1	hSpCas9	negative selection	2925548
147915203	147915226	2	-	27260157	SF268	viability	CCTAGTAATGGAGAAGGTGGGGG	ACVR2A	ENSG00000121989	-0.412507697870829	[]	[]	-3	hSpCas9	negative selection	2926905
147845186	147845209	2	+	27260157	SF268	viability	TTTCTTATCTCCTGTTCTTCAGG	ACVR2A	ENSG00000121989	-0.567768609108503	[]	[]	-4	hSpCas9	negative selection	2948338
147915242	147915265	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTATTAGAAGTGAAAGCAAGGG	ACVR2A	ENSG00000121989	-0.19974136290987415	[2,3]	[2,1]	-3	hSpCas9	positive selection	2968797
147915243	147915266	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATTAGAAGTGAAAGCAAGGGG	ACVR2A	ENSG00000121989	-0.13233184854156502	[2,2]	[2,1]	-2	hSpCas9	positive selection	2968798
147915242	147915265	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTATTAGAAGTGAAAGCAAGGG	ACVR2A	ENSG00000121989	0.167808374219595	[2,2]	[2,1]	3	hSpCas9	positive selection	3036655
147915243	147915266	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATTAGAAGTGAAAGCAAGGGG	ACVR2A	ENSG00000121989	-0.32987522782566386	[2,2]	[2,0]	-5	hSpCas9	positive selection	3036656
147915289	147915312	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-1.2453041238610008	[392,331]	[0,0]	-8	hSpCas9	positive selection	3335477
147915289	147915312	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.5024387092823666	[107,107]	[0,0]	2	hSpCas9	positive selection	3354723
147915241	147915264	2	+	26780180	HT29	viability (Avana library 4 designs)	GTTATTAGAAGTGAAAGCAAGGG	ACVR2A	ENSG00000121989	2.37993985940332	[]	[]	8	hSpCas9	negative selection	3404747
147915242	147915265	2	+	26780180	HT29	viability (Avana library 4 designs)	TTATTAGAAGTGAAAGCAAGGGG	ACVR2A	ENSG00000121989	2.02673480023063	[]	[]	7	hSpCas9	negative selection	3404748
147915242	147915265	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATTAGAAGTGAAAGCAAGGGG	ACVR2A	ENSG00000121989	-9.69352492048694	[]	[]	-7	hSpCas9	negative selection	3476435
147915241	147915264	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTATTAGAAGTGAAAGCAAGGG	ACVR2A	ENSG00000121989	-15.8927931916056	[]	[]	-9	hSpCas9	negative selection	3476436
147918514	147918537	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.516719521905919	[]	[]	0	hSpCas9	negative selection	3476437
147915200	147915223	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTAATGGAGAAGGTGGGGGTGG	ACVR2A	ENSG00000121989	4.09819867090036	[]	[]	6	hSpCas9	negative selection	3476438
147915242	147915265	2	+	26780180	A375	viability (Avana lentiGuide)	TTATTAGAAGTGAAAGCAAGGGG	ACVR2A	ENSG00000121989	3.20458959491916	[]	[]	3	hSpCas9	negative selection	3585094
147915241	147915264	2	+	26780180	A375	viability (Avana lentiGuide)	GTTATTAGAAGTGAAAGCAAGGG	ACVR2A	ENSG00000121989	-5.68877602117106	[]	[]	-8	hSpCas9	negative selection	3585095
147918514	147918537	2	-	26780180	A375	viability (Avana lentiGuide)	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.762557398456481	[]	[]	0	hSpCas9	negative selection	3585096
147915200	147915223	2	-	26780180	A375	viability (Avana lentiGuide)	AGTAATGGAGAAGGTGGGGGTGG	ACVR2A	ENSG00000121989	0.298618440253821	[]	[]	0	hSpCas9	negative selection	3585097
147915242	147915265	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATTAGAAGTGAAAGCAAGGGG	ACVR2A	ENSG00000121989	-0.8055117610803446	[7]	[5,2]	-8	hSpCas9	positive selection	3693753
147915241	147915264	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTATTAGAAGTGAAAGCAAGGG	ACVR2A	ENSG00000121989	-1.036111364774217	[6]	[1,2]	-9	hSpCas9	positive selection	3693754
147918514	147918537	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.0371114902723232	[5]	[5,3]	0	hSpCas9	positive selection	3693755
147915200	147915223	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTAATGGAGAAGGTGGGGGTGG	ACVR2A	ENSG00000121989	0.29975864308696415	[4]	[6,5]	8	hSpCas9	positive selection	3693756
147915242	147915265	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATTAGAAGTGAAAGCAAGGGG	ACVR2A	ENSG00000121989	0.09769448038144954	[4]	[2,5]	2	hSpCas9	positive selection	3802360
147915241	147915264	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTATTAGAAGTGAAAGCAAGGG	ACVR2A	ENSG00000121989	0.3113262792523666	[4]	[4,4]	8	hSpCas9	positive selection	3802361
147918514	147918537	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.11929597519783584	[5]	[3,6]	2	hSpCas9	positive selection	3802362
147915200	147915223	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTAATGGAGAAGGTGGGGGTGG	ACVR2A	ENSG00000121989	-0.35060979082003335	[5]	[3,2]	-4	hSpCas9	positive selection	3802363
147915289	147915312	2	-	26780180	A375	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	1.25589441774988	[]	[]	6	hSpCas9	negative selection	3910962
147915289	147915312	2	+	26780180	A375	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.4284424141019	[]	[]	1	hSpCas9	negative selection	3910963
147915289	147915312	2	-	26780180	HT29	viability (GeCKOv2 library)	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	1.63887361550217	[]	[]	8	hSpCas9	negative selection	4018928
147915289	147915312	2	+	26780180	HT29	viability (GeCKOv2 library)	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	1.09023321482017	[]	[]	5	hSpCas9	negative selection	4018929
147915289	147915312	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.1610675912107113	[4]	[4,3]	3	hSpCas9	positive selection	4254400
147915289	147915312	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.1531906269847167	[2]	[3,1]	3	hSpCas9	positive selection	4318681
147915215	147915237	2	-	27760321	OCIAML3	viability	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-1.7046781185012776	[25,22]	[4,6]	-8	hSpCas9	negative selection	4375996
147915288	147915310	2	-	27760321	OCIAML3	viability	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	0.06615468875558639	[73,55]	[57,45]	0	hSpCas9	negative selection	4375997
147918514	147918536	2	-	27760321	OCIAML3	viability	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4375998
147918535	147918557	2	+	27760321	OCIAML3	viability	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-2.3044406152045767	[8,3]	[0,0]	-9	hSpCas9	negative selection	4375999
147915215	147915237	2	-	27760321	OCIAML2	viability	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-0.6498486342643419	[25,22]	[6,19]	-6	hSpCas9	negative selection	4459459
147915288	147915310	2	-	27760321	OCIAML2	viability	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	-1.398224414928261	[73,55]	[8,33]	-8	hSpCas9	negative selection	4459460
147918514	147918536	2	-	27760321	OCIAML2	viability	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4459461
147918535	147918557	2	+	27760321	OCIAML2	viability	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-2.3531859804696253	[8,3]	[0,0]	-9	hSpCas9	negative selection	4459462
147915215	147915237	2	-	27760321	MV411	viability	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	0.10737112305138918	[25,22]	[0,41]	0	hSpCas9	negative selection	4542922
147915288	147915310	2	-	27760321	MV411	viability	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	0.26026984471805514	[73,55]	[0,125]	1	hSpCas9	negative selection	4542923
147918514	147918536	2	-	27760321	MV411	viability	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4542924
147918535	147918557	2	+	27760321	MV411	viability	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-2.0593620462898947	[8,3]	[0,0]	-8	hSpCas9	negative selection	4542925
147915215	147915237	2	-	27760321	HL60	viability	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	1.117761575098251	[25,22]	[21,65]	9	hSpCas9	negative selection	4626385
147915288	147915310	2	-	27760321	HL60	viability	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	-0.2255244716683804	[73,55]	[29,60]	-3	hSpCas9	negative selection	4626386
147918514	147918536	2	-	27760321	HL60	viability	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4626387
147918535	147918557	2	+	27760321	HL60	viability	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-2.3672322080840313	[8,3]	[0,0]	-9	hSpCas9	negative selection	4626388
147915215	147915237	2	-	27760321	HT1080	viability	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-3.029980070239602	[22,17]	[0,0]	-7	hSpCas9	negative selection	4709848
147915288	147915310	2	-	27760321	HT1080	viability	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	-4.316638003739513	[55,43]	[0,0]	-8	hSpCas9	negative selection	4709849
147918514	147918536	2	-	27760321	HT1080	viability	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4709850
147918535	147918557	2	+	27760321	HT1080	viability	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-0.4759873735460216	[3,2]	[0,0]	-2	hSpCas9	negative selection	4709851
147915215	147915237	2	-	27760321	HT29	viability after 7 days	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-0.9874699211399536	[22,17]	[3,3,29]	-8	hSpCas9	negative selection	4793311
147915288	147915310	2	-	27760321	HT29	viability after 7 days	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	0.6088740330422167	[55,43]	[121,92,82]	8	hSpCas9	negative selection	4793312
147918514	147918536	2	-	27760321	HT29	viability after 7 days	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4793313
147918535	147918557	2	+	27760321	HT29	viability after 7 days	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-2.165647627095286	[3,2]	[0,0,0]	-9	hSpCas9	negative selection	4793314
147915215	147915237	2	-	27760321	HT29	viability after 25 days	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-2.727814128526748	[22,17]	[2,0,6]	-8	hSpCas9	negative selection	4876774
147915288	147915310	2	-	27760321	HT29	viability after 25 days	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	-1.263313980037498	[55,43]	[2,8,64]	-7	hSpCas9	negative selection	4876775
147918514	147918536	2	-	27760321	HT29	viability after 25 days	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4876776
147918535	147918557	2	+	27760321	HT29	viability after 25 days	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-1.9956696383925454	[3,2]	[0,0,0]	-8	hSpCas9	negative selection	4876777
147915215	147915237	2	-	27760321	HT29	viability after 22 days	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-0.8149132647822546	[22,17]	[0,0,38]	-6	hSpCas9	negative selection	4960237
147915288	147915310	2	-	27760321	HT29	viability after 22 days	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	-0.33305415457527365	[55,43]	[16,22,98]	-3	hSpCas9	negative selection	4960238
147918514	147918536	2	-	27760321	HT29	viability after 22 days	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4960239
147918535	147918557	2	+	27760321	HT29	viability after 22 days	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-2.012988270251805	[3,2]	[0,0,0]	-8	hSpCas9	negative selection	4960240
147915215	147915237	2	-	27760321	HT29	viability after 19 days	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-0.7436398645590101	[22,17]	[2,0,35]	-5	hSpCas9	negative selection	5043700
147915288	147915310	2	-	27760321	HT29	viability after 19 days	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	0.17495059072880714	[55,43]	[57,69,64]	1	hSpCas9	negative selection	5043701
147918514	147918536	2	-	27760321	HT29	viability after 19 days	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5043702
147918535	147918557	2	+	27760321	HT29	viability after 19 days	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-1.9971482178285918	[3,2]	[0,0,0]	-8	hSpCas9	negative selection	5043703
147915215	147915237	2	-	27760321	HT29	viability after 16 days	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-0.8719985049822929	[22,17]	[2,0,32]	-6	hSpCas9	negative selection	5127163
147915288	147915310	2	-	27760321	HT29	viability after 16 days	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	-0.25897830301777525	[55,43]	[29,73,33]	-3	hSpCas9	negative selection	5127164
147918514	147918536	2	-	27760321	HT29	viability after 16 days	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5127165
147918535	147918557	2	+	27760321	HT29	viability after 16 days	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-1.96568376540767	[3,2]	[0,0,0]	-8	hSpCas9	negative selection	5127166
147915215	147915237	2	-	27760321	HT29	viability after 13 days	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	2.472692056269087	[22,17]	[318,1,77]	9	hSpCas9	negative selection	5210626
147915288	147915310	2	-	27760321	HT29	viability after 13 days	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	-0.4438655919028882	[55,43]	[22,61,42]	-5	hSpCas9	negative selection	5210627
147918514	147918536	2	-	27760321	HT29	viability after 13 days	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5210628
147918535	147918557	2	+	27760321	HT29	viability after 13 days	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-2.017971164851808	[3,2]	[0,0,0]	-8	hSpCas9	negative selection	5210629
147915215	147915237	2	-	27760321	HT29	viability after 10 days	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-0.13356289968282464	[22,17]	[43,13,11]	-2	hSpCas9	negative selection	5294089
147915288	147915310	2	-	27760321	HT29	viability after 10 days	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	0.4144364663751787	[55,43]	[29,52,163]	5	hSpCas9	negative selection	5294090
147918514	147918536	2	-	27760321	HT29	viability after 10 days	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5294091
147918535	147918557	2	+	27760321	HT29	viability after 10 days	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-2.123982472012152	[3,2]	[0,0,0]	-9	hSpCas9	negative selection	5294092
147915215	147915237	2	-	27760321	MOLM13	viability	GTGGTTTCAAACCTAGTAATGG	ACVR2A	ENSG00000121989	-3.7864595105493484	[25,22]	[0,0]	-9	hSpCas9	negative selection	5377552
147915288	147915310	2	-	27760321	MOLM13	viability	ACATATTCGTTAAGCAACTGGG	ACVR2A	ENSG00000121989	-1.7623033045784946	[73,55]	[0,18]	-7	hSpCas9	negative selection	5377553
147918514	147918536	2	-	27760321	MOLM13	viability	TATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5377554
147918535	147918557	2	+	27760321	MOLM13	viability	ATTTACATGAGGATATACCTGG	ACVR2A	ENSG00000121989	-1.8333052334622995	[8,3]	[0,0]	-7	hSpCas9	negative selection	5377555
147844778	147844801	2	-	27661255	K562	viability	GCCAGGCTGAGGCGACGAAGAGG	ACVR2A	ENSG00000121989	0.30948015720566147	[316,413]	[385,337]	8	dCas9-KRAB	negative selection	5460818
147915289	147915312	2	+	27260156	BXPC3	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.1367731060044246	[1222]	[1301,1328,1372,1655]	3	hSpCas9	negative selection	5526860
147915289	147915312	2	-	27260156	BXPC3	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.23764921518759796	[440]	[360,353,447,406]	-5	hSpCas9	negative selection	5591141
147915289	147915312	2	+	27260156	A673	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.012288536851537302	[1222]	[1870,1293,1246,1565]	0	hSpCas9	negative selection	5648111
147915289	147915312	2	-	27260156	A673	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.3454896002083636	[440]	[472,358,353,492]	-7	hSpCas9	negative selection	5712392
147915289	147915312	2	+	27260156	A375	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.09928979815375061	[1222]	[2077,1709,1149,1240]	1	hSpCas9	negative selection	5769362
147915289	147915312	2	-	27260156	A375	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.11563483741012569	[440]	[429,509,467,493]	-2	hSpCas9	negative selection	5833643
147915289	147915312	2	+	27260156	COLO741	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.11626014044976585	[1222]	[1495,1524,1314]	-2	hSpCas9	negative selection	5890613
147915289	147915312	2	-	27260156	COLO741	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.15373830545112419	[440]	[832,531,537]	3	hSpCas9	negative selection	5954894
147915289	147915312	2	+	27260156	CAL120	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.33329343153916247	[1222]	[1217,1205,1200]	-5	hSpCas9	negative selection	6011864
147915289	147915312	2	-	27260156	CAL120	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.4060961691980416	[440]	[447,421,377]	-5	hSpCas9	negative selection	6076145
147915289	147915312	2	+	27260156	CADOES1	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.11767460648300987	[1222]	[871,1188,936,1201]	-2	hSpCas9	negative selection	6133115
147915289	147915312	2	-	27260156	CADOES1	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.32713193100416904	[440]	[220,357,327,403]	-5	hSpCas9	negative selection	6197396
147915289	147915312	2	+	27260156	EWS502	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.2563679394786369	[1222]	[1066,947,1301,1022]	-4	hSpCas9	negative selection	6254366
147915289	147915312	2	-	27260156	EWS502	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.18603593305641702	[440]	[239,435,410,585]	-3	hSpCas9	negative selection	6318647
147915289	147915312	2	+	27260156	EW8	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.0017379115380020682	[1222]	[1343,987,862,822]	0	hSpCas9	negative selection	6375617
147915289	147915312	2	-	27260156	EW8	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.06957108378969055	[440]	[407,385,263,323]	-1	hSpCas9	negative selection	6439898
147915289	147915312	2	+	27260156	CORL105	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.19346871279381173	[1222]	[1619,1572,1920,1479]	3	hSpCas9	negative selection	6496868
147915289	147915312	2	-	27260156	CORL105	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.0575661209671946	[440]	[540,519,634,468]	1	hSpCas9	negative selection	6561149
147915289	147915312	2	+	27260156	HS294T	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.020041732309669102	[1222]	[457,397,506,573]	0	hSpCas9	negative selection	6618119
147915289	147915312	2	-	27260156	HS294T	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.3834194505899062	[440]	[217,380,91,186]	5	hSpCas9	negative selection	6682400
147915289	147915312	2	+	27260156	HCC44	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.16309876055080674	[1222]	[1156,914,1581,1370]	-3	hSpCas9	negative selection	6739370
147915289	147915312	2	-	27260156	HCC44	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.3424852140884063	[440]	[561,370,382,274]	-5	hSpCas9	negative selection	6803651
147915289	147915312	2	+	27260156	G402	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.1541838161637985	[1222]	[1219,1262,1640,1218]	-2	hSpCas9	negative selection	6860621
147915289	147915312	2	-	27260156	G402	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.3600450527087945	[440]	[658,430,657,977]	4	hSpCas9	negative selection	6924902
147915289	147915312	2	+	27260156	L33	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.16522978816306466	[1222]	[1378,495,910,1445]	3	hSpCas9	negative selection	6981872
147915289	147915312	2	-	27260156	L33	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.18789437568246303	[440]	[383,156,224,422]	-4	hSpCas9	negative selection	7046153
147915289	147915312	2	+	27260156	K562	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.04727238878361972	[1222]	[1456,899,1236,672]	0	hSpCas9	negative selection	7103123
147915289	147915312	2	-	27260156	K562	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.15077751701303949	[440]	[256,440,439,567]	1	hSpCas9	negative selection	7167404
147915289	147915312	2	+	27260156	HT29	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.07750169430956744	[1222]	[1492,1441,1346,1358]	-2	hSpCas9	negative selection	7224374
147915289	147915312	2	-	27260156	HT29	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.15880488776488216	[440]	[621,479,424,409]	-3	hSpCas9	negative selection	7288655
147915289	147915312	2	+	27260156	MHHES1	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.2345927527694358	[1222]	[1491,1236,1215,835]	-4	hSpCas9	negative selection	7345625
147915289	147915312	2	-	27260156	MHHES1	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.08507243057636092	[440]	[704,532,328,355]	-1	hSpCas9	negative selection	7409906
147915289	147915312	2	+	27260156	MEWO	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.12932293546895868	[1222]	[1041,890,1204]	-3	hSpCas9	negative selection	7466876
147915289	147915312	2	-	27260156	MEWO	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.5215238259170387	[440]	[296,297,268]	-8	hSpCas9	negative selection	7531157
147915289	147915312	2	+	27260156	LNCAPCLONEFGC	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.29487938632555055	[1222]	[895,847,1088,809]	-4	hSpCas9	negative selection	7588127
147915289	147915312	2	-	27260156	LNCAPCLONEFGC	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.07627946009765026	[440]	[300,333,426,464]	-1	hSpCas9	negative selection	7652408
147915289	147915312	2	+	27260156	PANC0327	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.012668435884217066	[1222]	[981,1135,1075,1174]	0	hSpCas9	negative selection	7709378
147915289	147915312	2	-	27260156	PANC0327	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.4815459435982973	[440]	[289,164,360,321]	-6	hSpCas9	negative selection	7773659
147915289	147915312	2	+	27260156	NCIH2009	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.2157918040578748	[1222]	[1639,1517,1285]	-3	hSpCas9	negative selection	7830629
147915289	147915312	2	-	27260156	NCIH2009	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.05217520894150674	[440]	[615,633,660]	0	hSpCas9	negative selection	7894910
147915289	147915312	2	+	27260156	NCIH1373	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.20385766959022456	[1222]	[1692,948,1228,255]	-2	hSpCas9	negative selection	7951880
147915289	147915312	2	-	27260156	NCIH1373	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.3004001058155401	[440]	[528,694,776,102]	3	hSpCas9	negative selection	8016161
147915289	147915312	2	+	27260156	PATU8902	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.15587998287680738	[1222]	[1645,1655,1528,2970]	1	hSpCas9	negative selection	8073131
147915289	147915312	2	-	27260156	PATU8902	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.46433425038760207	[440]	[735,710,806,1179]	5	hSpCas9	negative selection	8137412
147915289	147915312	2	+	27260156	PANC1	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.40380008166261927	[1222]	[981,1205,483,600]	-6	hSpCas9	negative selection	8194382
147915289	147915312	2	-	27260156	PANC1	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.13563825513365818	[440]	[320,549,305,253]	-2	hSpCas9	negative selection	8258663
147915289	147915312	2	+	27260156	PANC0813	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.08982104179457973	[1222]	[1313,1555,1748,1477]	1	hSpCas9	negative selection	8315633
147915289	147915312	2	-	27260156	PANC0813	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.2848401711899485	[440]	[471,363,467,401]	-4	hSpCas9	negative selection	8379914
147915289	147915312	2	+	27260156	RDES	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.19635101172142977	[1222]	[1118,1134,1128,1567]	-3	hSpCas9	negative selection	8436884
147915289	147915312	2	-	27260156	RDES	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.0753232167627605	[440]	[450,441,528,502]	-1	hSpCas9	negative selection	8501165
147915289	147915312	2	+	27260156	PC3	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.29121373213315005	[1222]	[599,800,1929,1115]	-6	hSpCas9	negative selection	8558135
147915289	147915312	2	-	27260156	PC3	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.1833830390719539	[440]	[324,265,583,437]	-4	hSpCas9	negative selection	8622416
147915289	147915312	2	+	27260156	PATU8988T	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.2790298786154226	[1222]	[1641,1286,1240,1564]	5	hSpCas9	negative selection	8679386
147915289	147915312	2	-	27260156	PATU8988T	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.6907771333869076	[440]	[130,332,327,269]	-8	hSpCas9	negative selection	8743667
147915289	147915312	2	+	27260156	T47D	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.1812920606626438	[1222]	[1319,1191,1231,1288]	-4	hSpCas9	negative selection	8800637
147915289	147915312	2	-	27260156	T47D	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.2512349350824777	[440]	[321,442,414,548]	-5	hSpCas9	negative selection	8864918
147915289	147915312	2	+	27260156	SU8686	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.24091598033671047	[1222]	[1313,1288,1459,1740]	4	hSpCas9	negative selection	8921888
147915289	147915312	2	-	27260156	SU8686	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.1722918846910801	[440]	[323,337,351,578]	-3	hSpCas9	negative selection	8986169
147915289	147915312	2	+	27260156	SKES1	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.08915958820188408	[1222]	[1284,998,1180,1114]	-2	hSpCas9	negative selection	9043139
147915289	147915312	2	-	27260156	SKES1	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.32118964302600134	[440]	[312,463,277,357]	-6	hSpCas9	negative selection	9107420
147915289	147915312	2	+	27260156	TOV112D	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.0953047300122234	[1222]	[1101,1261,1057,1185]	-2	hSpCas9	negative selection	9164390
147915289	147915312	2	-	27260156	TOV112D	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.19654310927724727	[440]	[414,422,335,378]	-4	hSpCas9	negative selection	9228671
147915289	147915312	2	+	27260156	TC71	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	0.01111704038074568	[1222]	[1334,1441,1173,1338]	0	hSpCas9	negative selection	9285641
147915289	147915312	2	-	27260156	TC71	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	-0.6706625826299453	[440]	[271,284,275,359]	-9	hSpCas9	negative selection	9349922
147915289	147915312	2	+	27260156	TC32	viability	CCAGTTGCTTAACGAATATGTGG	ACVR2A	ENSG00000121989	-0.26186941315866363	[1222]	[899,561,1385,1176]	-5	hSpCas9	negative selection	9406892
147915289	147915312	2	-	27260156	TC32	viability	CCACATATTCGTTAAGCAACTGG	ACVR2A	ENSG00000121989	0.030544442953578728	[440]	[288,362,466,606]	0	hSpCas9	negative selection	9471173
147845196	147845219	2	-	27869803	HPAFII	viability after 27 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	1.2261585729390774	[717]	[773,973,NaN]	8	hSpCas9	negative selection	9571832
147918514	147918537	2	-	27869803	HPAFII	viability after 27 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	1.83023823246264	[270]	[702,342,NaN]	9	hSpCas9	negative selection	9571833
147920323	147920346	2	+	27869803	HPAFII	viability after 27 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	0.32485869075652896	[508]	[554,151,NaN]	2	hSpCas9	negative selection	9571834
147922981	147923004	2	+	27869803	HPAFII	viability after 27 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.44093643903879726	[441]	[192,152,NaN]	-3	hSpCas9	negative selection	9571835
147927117	147927140	2	+	27869803	HPAFII	viability after 27 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.9138534712641913	[191]	[91,271,NaN]	7	hSpCas9	negative selection	9571836
147845196	147845219	2	-	27869803	HPAFII	viability after 15 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.7400818251060692	[717]	[1545,1128,NaN]	8	hSpCas9	negative selection	9654281
147918514	147918537	2	-	27869803	HPAFII	viability after 15 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.5624429242102064	[270]	[722,247,NaN]	6	hSpCas9	negative selection	9654282
147920323	147920346	2	+	27869803	HPAFII	viability after 15 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	0.028538387825501887	[508]	[1078,233,NaN]	0	hSpCas9	negative selection	9654283
147922981	147923004	2	+	27869803	HPAFII	viability after 15 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.08514791051255244	[441]	[506,410,NaN]	-1	hSpCas9	negative selection	9654284
147927117	147927140	2	+	27869803	HPAFII	viability after 15 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.6666088737278963	[191]	[440,256,NaN]	7	hSpCas9	negative selection	9654285
147845196	147845219	2	-	27869803	ASPC1	viability after 36 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	-0.12786328330265273	[2052]	[980,530,519]	-1	hSpCas9	negative selection	9736730
147918514	147918537	2	-	27869803	ASPC1	viability after 36 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.14156801136878405	[685]	[116,366,165]	-1	hSpCas9	negative selection	9736731
147920323	147920346	2	+	27869803	ASPC1	viability after 36 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	-0.11761702974786847	[1310]	[206,630,401]	-1	hSpCas9	negative selection	9736732
147922981	147923004	2	+	27869803	ASPC1	viability after 36 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.5605061300289819	[975]	[508,169,81]	-5	hSpCas9	negative selection	9736733
147927117	147927140	2	+	27869803	ASPC1	viability after 36 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	-0.20074694403476756	[463]	[172,92,154]	-2	hSpCas9	negative selection	9736734
147845196	147845219	2	-	27869803	PATU8988S	viability after 35 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.7447352718442102	[1535]	[1083,988,NaN]	7	hSpCas9	negative selection	9819179
147918514	147918537	2	-	27869803	PATU8988S	viability after 35 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	0.3692782237476664	[641]	[329,337,NaN]	4	hSpCas9	negative selection	9819180
147920323	147920346	2	+	27869803	PATU8988S	viability after 35 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	0.10413231118166277	[1195]	[404,630,NaN]	1	hSpCas9	negative selection	9819181
147922981	147923004	2	+	27869803	PATU8988S	viability after 35 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.5569688995413485	[776]	[409,510,NaN]	6	hSpCas9	negative selection	9819182
147927117	147927140	2	+	27869803	PATU8988S	viability after 35 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.9560857551759692	[455]	[485,225,NaN]	8	hSpCas9	negative selection	9819183
147845196	147845219	2	-	27869803	PATU8988S	viability after 31 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	0.5476103837792925	[1535]	[819,990,NaN]	6	hSpCas9	negative selection	9901628
147918514	147918537	2	-	27869803	PATU8988S	viability after 31 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	-0.0156504121518391	[641]	[210,306,NaN]	0	hSpCas9	negative selection	9901629
147920323	147920346	2	+	27869803	PATU8988S	viability after 31 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	0.06850494990199318	[1195]	[540,447,NaN]	0	hSpCas9	negative selection	9901630
147922981	147923004	2	+	27869803	PATU8988S	viability after 31 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.2963329731935094	[776]	[328,445,NaN]	3	hSpCas9	negative selection	9901631
147927117	147927140	2	+	27869803	PATU8988S	viability after 31 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.2420743126740871	[455]	[240,181,NaN]	3	hSpCas9	negative selection	9901632
147845196	147845219	2	-	27869803	HPAFII	viability after 35 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	1.6598556518795045	[717]	[847,1486,NaN]	9	hSpCas9	negative selection	9984077
147918514	147918537	2	-	27869803	HPAFII	viability after 35 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	2.3651348529108334	[270]	[933,450,NaN]	9	hSpCas9	negative selection	9984078
147920323	147920346	2	+	27869803	HPAFII	viability after 35 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	0.9416901342318886	[508]	[620,352,NaN]	6	hSpCas9	negative selection	9984079
147922981	147923004	2	+	27869803	HPAFII	viability after 35 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	0.05435287212166162	[441]	[110,368,NaN]	0	hSpCas9	negative selection	9984080
147927117	147927140	2	+	27869803	HPAFII	viability after 35 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.7021694270021166	[191]	[80,244,NaN]	4	hSpCas9	negative selection	9984081
147845196	147845219	2	-	27869803	HPAFII	viability after 31 days	CCTGCACCTACCTGAAGAACAGG	ACVR2A	ENSG00000121989	1.4715072865323413	[717]	[914,1337,NaN]	9	hSpCas9	negative selection	10066526
147918514	147918537	2	-	27869803	HPAFII	viability after 31 days	ATATGCCAATCCTCTAGCCATGG	ACVR2A	ENSG00000121989	2.169466329219871	[270]	[933,411,NaN]	9	hSpCas9	negative selection	10066527
147920323	147920346	2	+	27869803	HPAFII	viability after 31 days	TGCAGGCGATACCCATGGACAGG	ACVR2A	ENSG00000121989	0.628235680543614	[508]	[620,245,NaN]	4	hSpCas9	negative selection	10066528
147922981	147923004	2	+	27869803	HPAFII	viability after 31 days	CCGGAGGTACATGGCTCCAGAGG	ACVR2A	ENSG00000121989	-0.38229131008670647	[441]	[107,279,NaN]	-3	hSpCas9	negative selection	10066529
147927117	147927140	2	+	27869803	HPAFII	viability after 31 days	GGGATCACGACGCAGAAGCCAGG	ACVR2A	ENSG00000121989	0.10024695808398054	[191]	[70,163,NaN]	0	hSpCas9	negative selection	10066530
147896397	147896420	2	+	28162770	P31FUJ	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.12350147007399903	[281]	[360]	1	hSpCas9	negative selection	10106634
147923010	147923033	2	+	28162770	P31FUJ	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	0.7614614260364767	[125]	[250]	8	hSpCas9	negative selection	10106635
147923044	147923067	2	+	28162770	P31FUJ	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	-0.142347253468875	[339]	[361]	-1	hSpCas9	negative selection	10106636
147915206	147915229	2	-	28162770	P31FUJ	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	0.23432380601291936	[101]	[140]	2	hSpCas9	negative selection	10106637
147917275	147917298	2	+	28162770	P31FUJ	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.614019868980462	[272]	[490]	7	hSpCas9	negative selection	10106638
147918497	147918520	2	+	28162770	P31FUJ	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.16910786087885277	[413]	[546]	1	hSpCas9	negative selection	10106639
147918546	147918569	2	+	28162770	P31FUJ	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	0.9480939148489369	[130]	[296]	9	hSpCas9	negative selection	10106640
147920318	147920341	2	+	28162770	P31FUJ	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	-0.08470356542524471	[147]	[163]	-1	hSpCas9	negative selection	10106641
147896397	147896420	2	+	28162770	TF1	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10276000
147923010	147923033	2	+	28162770	TF1	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	NaN	[NaN]	[45]	1	hSpCas9	negative selection	10276001
147923044	147923067	2	+	28162770	TF1	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	NaN	[NaN]	[248]	1	hSpCas9	negative selection	10276002
147915206	147915229	2	-	28162770	TF1	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	NaN	[NaN]	[88]	1	hSpCas9	negative selection	10276003
147917275	147917298	2	+	28162770	TF1	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	NaN	[NaN]	[659]	1	hSpCas9	negative selection	10276004
147918497	147918520	2	+	28162770	TF1	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	NaN	[NaN]	[265]	1	hSpCas9	negative selection	10276005
147918546	147918569	2	+	28162770	TF1	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10276006
147920318	147920341	2	+	28162770	TF1	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10276007
147896397	147896420	2	+	28162770	SKM1	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	-0.08910576816484639	[70]	[117]	-1	hSpCas9	negative selection	10445366
147923010	147923033	2	+	28162770	SKM1	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	0.15290732101516402	[28]	[56]	1	hSpCas9	negative selection	10445367
147923044	147923067	2	+	28162770	SKM1	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.18581780643729384	[91]	[184]	1	hSpCas9	negative selection	10445368
147915206	147915229	2	-	28162770	SKM1	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	0.8978903827852593	[33]	[111]	8	hSpCas9	negative selection	10445369
147917275	147917298	2	+	28162770	SKM1	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.5626621522133195	[71]	[187]	5	hSpCas9	negative selection	10445370
147918497	147918520	2	+	28162770	SKM1	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.8747748060285017	[90]	[294]	8	hSpCas9	negative selection	10445371
147918546	147918569	2	+	28162770	SKM1	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	0.2849135058945065	[25]	[55]	2	hSpCas9	negative selection	10445372
147920318	147920341	2	+	28162770	SKM1	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	-0.19195130777231129	[41]	[64]	-2	hSpCas9	negative selection	10445373
147896397	147896420	2	+	28162770	SKM1	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	-0.08910576816484639	[70]	[117]	-1	hSpCas9	negative selection	10614732
147923010	147923033	2	+	28162770	SKM1	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	0.15290732101516402	[28]	[56]	1	hSpCas9	negative selection	10614733
147923044	147923067	2	+	28162770	SKM1	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.18581780643729384	[91]	[184]	1	hSpCas9	negative selection	10614734
147915206	147915229	2	-	28162770	SKM1	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	0.8978903827852593	[33]	[111]	8	hSpCas9	negative selection	10614735
147917275	147917298	2	+	28162770	SKM1	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.5626621522133195	[71]	[187]	5	hSpCas9	negative selection	10614736
147918497	147918520	2	+	28162770	SKM1	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.8747748060285017	[90]	[294]	8	hSpCas9	negative selection	10614737
147918546	147918569	2	+	28162770	SKM1	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	0.2849135058945065	[25]	[55]	2	hSpCas9	negative selection	10614738
147920318	147920341	2	+	28162770	SKM1	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	-0.19195130777231129	[41]	[64]	-2	hSpCas9	negative selection	10614739
147896397	147896420	2	+	28162770	PL21	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.9036465669782285	[252]	[205]	7	hSpCas9	negative selection	10784098
147923010	147923033	2	+	28162770	PL21	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	-0.896721924763269	[76]	[17]	-6	hSpCas9	negative selection	10784099
147923044	147923067	2	+	28162770	PL21	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.5567604275428418	[377]	[241]	5	hSpCas9	negative selection	10784100
147915206	147915229	2	-	28162770	PL21	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	-0.5676869433816466	[125]	[36]	-4	hSpCas9	negative selection	10784101
147917275	147917298	2	+	28162770	PL21	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	1.0051236320841772	[173]	[151]	8	hSpCas9	negative selection	10784102
147918497	147918520	2	+	28162770	PL21	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.484257621617993	[316]	[192]	4	hSpCas9	negative selection	10784103
147918546	147918569	2	+	28162770	PL21	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	-1.7384598408465366	[68]	[8]	-8	hSpCas9	negative selection	10784104
147920318	147920341	2	+	28162770	PL21	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	1.0232618524052408	[155]	[137]	8	hSpCas9	negative selection	10784105
147896397	147896420	2	+	28162770	P31FUJ	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.12350147007399903	[281]	[360]	1	hSpCas9	negative selection	10953464
147923010	147923033	2	+	28162770	P31FUJ	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	0.7614614260364767	[125]	[250]	8	hSpCas9	negative selection	10953465
147923044	147923067	2	+	28162770	P31FUJ	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	-0.142347253468875	[339]	[361]	-1	hSpCas9	negative selection	10953466
147915206	147915229	2	-	28162770	P31FUJ	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	0.23432380601291936	[101]	[140]	2	hSpCas9	negative selection	10953467
147917275	147917298	2	+	28162770	P31FUJ	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.614019868980462	[272]	[490]	7	hSpCas9	negative selection	10953468
147918497	147918520	2	+	28162770	P31FUJ	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.16910786087885277	[413]	[546]	1	hSpCas9	negative selection	10953469
147918546	147918569	2	+	28162770	P31FUJ	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	0.9480939148489369	[130]	[296]	9	hSpCas9	negative selection	10953470
147920318	147920341	2	+	28162770	P31FUJ	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	-0.08470356542524471	[147]	[163]	-1	hSpCas9	negative selection	10953471
147896397	147896420	2	+	28162770	OCIAML5	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.9945235144767074	[113]	[409]	8	hSpCas9	negative selection	11122830
147923010	147923033	2	+	28162770	OCIAML5	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	0.35796864395246797	[66]	[154]	3	hSpCas9	negative selection	11122831
147923044	147923067	2	+	28162770	OCIAML5	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.44134148401331563	[234]	[575]	4	hSpCas9	negative selection	11122832
147915206	147915229	2	-	28162770	OCIAML5	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	0.5193816598671641	[62]	[162]	4	hSpCas9	negative selection	11122833
147917275	147917298	2	+	28162770	OCIAML5	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.9755693822422733	[110]	[393]	8	hSpCas9	negative selection	11122834
147918497	147918520	2	+	28162770	OCIAML5	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.3515415568346041	[253]	[584]	3	hSpCas9	negative selection	11122835
147918546	147918569	2	+	28162770	OCIAML5	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	-0.8085649322274104	[97]	[100]	-5	hSpCas9	negative selection	11122836
147920318	147920341	2	+	28162770	OCIAML5	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	1.4237918753273806	[69]	[338]	9	hSpCas9	negative selection	11122837
147896397	147896420	2	+	28162770	EOL1	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.2560266592408357	[541]	[340]	2	hSpCas9	negative selection	11292196
147923010	147923033	2	+	28162770	EOL1	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	-0.047971492007358396	[103]	[52]	0	hSpCas9	negative selection	11292197
147923044	147923067	2	+	28162770	EOL1	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.6451056092151279	[618]	[509]	6	hSpCas9	negative selection	11292198
147915206	147915229	2	-	28162770	EOL1	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	-0.2009831105133244	[239]	[109]	-1	hSpCas9	negative selection	11292199
147917275	147917298	2	+	28162770	EOL1	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	1.0043268455495322	[298]	[315]	8	hSpCas9	negative selection	11292200
147918497	147918520	2	+	28162770	EOL1	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	-0.5510897387122808	[469]	[168]	-4	hSpCas9	negative selection	11292201
147918546	147918569	2	+	28162770	EOL1	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	-0.7223424782938233	[118]	[37]	-5	hSpCas9	negative selection	11292202
147920318	147920341	2	+	28162770	EOL1	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	-0.39738032331682804	[134]	[53]	-3	hSpCas9	negative selection	11292203
147896397	147896420	2	+	28162770	MOLM13	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.8509367665789856	[341]	[445]	6	hSpCas9	negative selection	11461562
147923010	147923033	2	+	28162770	MOLM13	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	0.5282619995240605	[116]	[121]	4	hSpCas9	negative selection	11461563
147923044	147923067	2	+	28162770	MOLM13	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	1.0931327867860017	[517]	[798]	8	hSpCas9	negative selection	11461564
147915206	147915229	2	-	28162770	MOLM13	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	1.7032063689705181	[126]	[298]	9	hSpCas9	negative selection	11461565
147917275	147917298	2	+	28162770	MOLM13	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	-0.3485562765838823	[397]	[225]	-2	hSpCas9	negative selection	11461566
147918497	147918520	2	+	28162770	MOLM13	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.0068656769915547144	[679]	[493]	0	hSpCas9	negative selection	11461567
147918546	147918569	2	+	28162770	MOLM13	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	1.1053193021598706	[188]	[293]	8	hSpCas9	negative selection	11461568
147920318	147920341	2	+	28162770	MOLM13	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	0.07646443948768533	[201]	[153]	0	hSpCas9	negative selection	11461569
147896397	147896420	2	+	28162770	HEL	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.6960136250427051	[318]	[330]	6	hSpCas9	negative selection	11630928
147923010	147923033	2	+	28162770	HEL	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	0.40976166002274317	[113]	[96]	3	hSpCas9	negative selection	11630929
147923044	147923067	2	+	28162770	HEL	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.721810402991556	[425]	[449]	6	hSpCas9	negative selection	11630930
147915206	147915229	2	-	28162770	HEL	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	1.1091617175461121	[130]	[180]	8	hSpCas9	negative selection	11630931
147917275	147917298	2	+	28162770	HEL	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.5487626837913432	[221]	[207]	4	hSpCas9	negative selection	11630932
147918497	147918520	2	+	28162770	HEL	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.359491205277054	[459]	[377]	3	hSpCas9	negative selection	11630933
147918546	147918569	2	+	28162770	HEL	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	-0.6633642957253227	[135]	[54]	-4	hSpCas9	negative selection	11630934
147920318	147920341	2	+	28162770	HEL	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	0.3363118306531826	[161]	[130]	2	hSpCas9	negative selection	11630935
147896397	147896420	2	+	28162770	MV411	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.26889066044909293	[266]	[270]	2	hSpCas9	negative selection	11800294
147923010	147923033	2	+	28162770	MV411	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	1.03226945621424	[82]	[142]	8	hSpCas9	negative selection	11800295
147923044	147923067	2	+	28162770	MV411	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.06377752393504199	[342]	[301]	0	hSpCas9	negative selection	11800296
147915206	147915229	2	-	28162770	MV411	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	1.6107855730501184	[102]	[264]	9	hSpCas9	negative selection	11800297
147917275	147917298	2	+	28162770	MV411	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.2398243666729001	[189]	[188]	2	hSpCas9	negative selection	11800298
147918497	147918520	2	+	28162770	MV411	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	-0.2666293244313678	[406]	[284]	-2	hSpCas9	negative selection	11800299
147918546	147918569	2	+	28162770	MV411	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	0.8119359489442158	[70]	[104]	7	hSpCas9	negative selection	11800300
147920318	147920341	2	+	28162770	MV411	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	0.48604848267735157	[138]	[163]	4	hSpCas9	negative selection	11800301
147896397	147896420	2	+	28162770	MONOMAC1	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.14259324956126757	[161]	[204]	1	hSpCas9	negative selection	11969660
147923010	147923033	2	+	28162770	MONOMAC1	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	-0.36368671646900497	[54]	[48]	-3	hSpCas9	negative selection	11969661
147923044	147923067	2	+	28162770	MONOMAC1	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	-0.21235764634330978	[283]	[280]	-2	hSpCas9	negative selection	11969662
147915206	147915229	2	-	28162770	MONOMAC1	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	0.7406788746861035	[70]	[135]	7	hSpCas9	negative selection	11969663
147917275	147917298	2	+	28162770	MONOMAC1	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.8542436578841394	[151]	[314]	7	hSpCas9	negative selection	11969664
147918497	147918520	2	+	28162770	MONOMAC1	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.017557203716487058	[211]	[245]	0	hSpCas9	negative selection	11969665
147918546	147918569	2	+	28162770	MONOMAC1	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	0.20432571532221355	[52]	[69]	2	hSpCas9	negative selection	11969666
147920318	147920341	2	+	28162770	MONOMAC1	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	2.3666779199575627	[113]	[673]	9	hSpCas9	negative selection	11969667
147896397	147896420	2	+	28162770	OCIAML2	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.45881689493253064	[54]	[418]	4	hSpCas9	negative selection	12139026
147923010	147923033	2	+	28162770	OCIAML2	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	-0.9204327426816818	[13]	[40]	-6	hSpCas9	negative selection	12139027
147923044	147923067	2	+	28162770	OCIAML2	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	0.37683968410681024	[75]	[546]	3	hSpCas9	negative selection	12139028
147915206	147915229	2	-	28162770	OCIAML2	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	1.2174261684430987	[17]	[231]	9	hSpCas9	negative selection	12139029
147917275	147917298	2	+	28162770	OCIAML2	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.06429199297939947	[43]	[254]	0	hSpCas9	negative selection	12139030
147918497	147918520	2	+	28162770	OCIAML2	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.03838382224569625	[51]	[295]	0	hSpCas9	negative selection	12139031
147918546	147918569	2	+	28162770	OCIAML2	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	1.1302742193480166	[14]	[181]	9	hSpCas9	negative selection	12139032
147920318	147920341	2	+	28162770	OCIAML2	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	0.7677749140829178	[15]	[150]	7	hSpCas9	negative selection	12139033
147896397	147896420	2	+	28162770	OCIAML3	viability	ATGGTGACAAAGATAAACGGCGG	ACVR2A	ENSG00000121989	0.9552507987153142	[74]	[438]	8	hSpCas9	negative selection	12308392
147923010	147923033	2	+	28162770	OCIAML3	viability	AGGGTGCTATAAACTTCCAAAGG	ACVR2A	ENSG00000121989	-0.7094848577440991	[12]	[23]	-5	hSpCas9	negative selection	12308393
147923044	147923067	2	+	28162770	OCIAML3	viability	GAGGATAGATATGTATGCCATGG	ACVR2A	ENSG00000121989	-0.30224151594705323	[86]	[212]	-2	hSpCas9	negative selection	12308394
147915206	147915229	2	-	28162770	OCIAML3	viability	AAACCTAGTAATGGAGAAGGTGG	ACVR2A	ENSG00000121989	0.21334728173344097	[29]	[104]	2	hSpCas9	negative selection	12308395
147917275	147917298	2	+	28162770	OCIAML3	viability	GACTCTAGGACAAACAGTCATGG	ACVR2A	ENSG00000121989	0.7952303895226253	[66]	[350]	7	hSpCas9	negative selection	12308396
147918497	147918520	2	+	28162770	OCIAML3	viability	GTGTCATATTGCAGAAACCATGG	ACVR2A	ENSG00000121989	0.38174481342915945	[104]	[412]	3	hSpCas9	negative selection	12308397
147918546	147918569	2	+	28162770	OCIAML3	viability	GATATACCTGGCCTAAAAGATGG	ACVR2A	ENSG00000121989	2.8183754055087027	[16]	[361]	9	hSpCas9	negative selection	12308398
147920318	147920341	2	+	28162770	OCIAML3	viability	AAGTCTGCAGGCGATACCCATGG	ACVR2A	ENSG00000121989	0.36819032696345255	[28]	[112]	3	hSpCas9	negative selection	12308399