| 142463872 | 142463895 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | AGCTTAGCCTGCTACCAACGAGG | ADGRB1 | ENSG00000181790 | 2.6327665547022283 | [3,0] | [5,1] | 8 | dCas9-VP64 | positive selection | 2428312 | 142463843 | 142463866 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGACTTTGGGCCGCAGACACAGG | ADGRB1 | ENSG00000181790 | 1.3942413461662886 | [18,20] | [10,11] | 5 | dCas9-VP64 | positive selection | 2428313 | 142463896 | 142463919 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGGGTGGGCTCTCTCAGAGGAGG | ADGRB1 | ENSG00000181790 | 1.0986966131003122 | [1,1] | [0,0] | 4 | dCas9-VP64 | positive selection | 2428314 | 142463872 | 142463895 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | AGCTTAGCCTGCTACCAACGAGG | ADGRB1 | ENSG00000181790 | -0.7828983349400344 | [68,133] | [14,22] | -7 | dCas9-VP64 | positive selection | 2523567 | 142463843 | 142463866 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGACTTTGGGCCGCAGACACAGG | ADGRB1 | ENSG00000181790 | 1.9399185746900809 | [30,199] | [12,263] | 8 | dCas9-VP64 | positive selection | 2523568 | 142463896 | 142463919 | 8 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGGGTGGGCTCTCTCAGAGGAGG | ADGRB1 | ENSG00000181790 | 0.5838665781885473 | [29,41] | [21,12] | 4 | dCas9-VP64 | positive selection | 2523569 | 142477138 | 142477161 | 8 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCTGGAGCACACGCTCCACGGGG | ADGRB1 | ENSG00000181790 | 0.339031546672115 | [] | [] | 1 | hSpCas9 | negative selection | 3405074 | 142464543 | 142464566 | 8 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GGGCGTGGAGAGCTTCGACGAGG | ADGRB1 | ENSG00000181790 | 1.90584625696506 | [] | [] | 7 | hSpCas9 | negative selection | 3405075 | 142475604 | 142475627 | 8 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GGGTCGCCAGTGCAACCGCGAGG | ADGRB1 | ENSG00000181790 | 1.89925978863439 | [] | [] | 7 | hSpCas9 | negative selection | 3405076 | 142481321 | 142481344 | 8 | - | 26780180 | HT29 | viability (Avana library 4 designs) | TGTAGTCAATGGAAACACAGCGG | ADGRB1 | ENSG00000181790 | -0.367177730772539 | [] | [] | -6 | hSpCas9 | negative selection | 3405077 | 142477138 | 142477161 | 8 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTGGAGCACACGCTCCACGGGG | ADGRB1 | ENSG00000181790 | 2.62549967642384 | [] | [] | 4 | hSpCas9 | negative selection | 3476914 | 142481321 | 142481344 | 8 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TGTAGTCAATGGAAACACAGCGG | ADGRB1 | ENSG00000181790 | -7.42123521441618 | [] | [] | -6 | hSpCas9 | negative selection | 3476915 | 142464543 | 142464566 | 8 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGGCGTGGAGAGCTTCGACGAGG | ADGRB1 | ENSG00000181790 | 2.54543917201678 | [] | [] | 4 | hSpCas9 | negative selection | 3476916 | 142475604 | 142475627 | 8 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGGTCGCCAGTGCAACCGCGAGG | ADGRB1 | ENSG00000181790 | 6.23101343633816 | [] | [] | 9 | hSpCas9 | negative selection | 3476917 | 142477138 | 142477161 | 8 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCTGGAGCACACGCTCCACGGGG | ADGRB1 | ENSG00000181790 | 4.25903465542809 | [] | [] | 4 | hSpCas9 | negative selection | 3585573 | 142481321 | 142481344 | 8 | - | 26780180 | A375 | viability (Avana lentiGuide) | TGTAGTCAATGGAAACACAGCGG | ADGRB1 | ENSG00000181790 | 1.96714066748612 | [] | [] | 2 | hSpCas9 | negative selection | 3585574 | 142464543 | 142464566 | 8 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGGCGTGGAGAGCTTCGACGAGG | ADGRB1 | ENSG00000181790 | 4.82019898255186 | [] | [] | 4 | hSpCas9 | negative selection | 3585575 | 142475604 | 142475627 | 8 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGGTCGCCAGTGCAACCGCGAGG | ADGRB1 | ENSG00000181790 | 5.41126202700458 | [] | [] | 5 | hSpCas9 | negative selection | 3585576 | 142477138 | 142477161 | 8 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTGGAGCACACGCTCCACGGGG | ADGRB1 | ENSG00000181790 | 0.2599564146069126 | [4] | [5,4] | 7 | hSpCas9 | positive selection | 3694232 | 142481321 | 142481344 | 8 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TGTAGTCAATGGAAACACAGCGG | ADGRB1 | ENSG00000181790 | -0.5525002311429614 | [6] | [4,2] | -7 | hSpCas9 | positive selection | 3694233 | 142464543 | 142464566 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGGCGTGGAGAGCTTCGACGAGG | ADGRB1 | ENSG00000181790 | -0.06980170915610584 | [3] | [3,2] | -1 | hSpCas9 | positive selection | 3694234 | 142475604 | 142475627 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGGTCGCCAGTGCAACCGCGAGG | ADGRB1 | ENSG00000181790 | 0.48583742731864177 | [4] | [5,6] | 9 | hSpCas9 | positive selection | 3694235 | 142477138 | 142477161 | 8 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTGGAGCACACGCTCCACGGGG | ADGRB1 | ENSG00000181790 | -0.003355617350231953 | [5] | [3,4] | 0 | hSpCas9 | positive selection | 3802839 | 142481321 | 142481344 | 8 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TGTAGTCAATGGAAACACAGCGG | ADGRB1 | ENSG00000181790 | 0.02187273615498128 | [6] | [6,4] | 0 | hSpCas9 | positive selection | 3802840 | 142464543 | 142464566 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGGCGTGGAGAGCTTCGACGAGG | ADGRB1 | ENSG00000181790 | -0.40657532605779423 | [5] | [3,3] | -5 | hSpCas9 | positive selection | 3802841 | 142475604 | 142475627 | 8 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGGTCGCCAGTGCAACCGCGAGG | ADGRB1 | ENSG00000181790 | -0.49038344128959577 | [3] | [0,3] | -6 | hSpCas9 | positive selection | 3802842 | 142464690 | 142464713 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.042520926882090804 | [2] | [2,1] | 0 | hSpCas9 | positive selection | 4257814 | 142464427 | 142464450 | 8 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.37749926743508133 | [1] | [1,0] | -7 | hSpCas9 | positive selection | 4257815 | 142475493 | 142475516 | 8 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.11542266579005958 | [2] | [3,1] | 2 | hSpCas9 | positive selection | 4257816 | 142475492 | 142475515 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.4630816322522785 | [1] | [0,0] | -7 | hSpCas9 | positive selection | 4322098 | 142476685 | 142476708 | 8 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.6577821463870133 | [2] | [1,0] | -9 | hSpCas9 | positive selection | 4322099 | 142476653 | 142476676 | 8 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.3076915810304911 | [2] | [2,2] | 6 | hSpCas9 | positive selection | 4322100 | 142464690 | 142464713 | 8 | + | 27260156 | BXPC3 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.002538555189483871 | [286] | [308,257,264,378] | 0 | hSpCas9 | negative selection | 5530274 | 142464427 | 142464450 | 8 | - | 27260156 | BXPC3 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.48433125061793025 | [143] | [103,100,123,100] | -8 | hSpCas9 | negative selection | 5530275 | 142475493 | 142475516 | 8 | - | 27260156 | BXPC3 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.10489840673496781 | [374] | [435,325,441,492] | 2 | hSpCas9 | negative selection | 5530276 | 142475492 | 142475515 | 8 | + | 27260156 | BXPC3 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | 0.11712009946280033 | [124] | [94,186,164,118] | 2 | hSpCas9 | negative selection | 5594558 | 142476685 | 142476708 | 8 | - | 27260156 | BXPC3 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.11055351558131793 | [351] | [288,402,320,350] | -3 | hSpCas9 | negative selection | 5594559 | 142476653 | 142476676 | 8 | + | 27260156 | BXPC3 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.025492351144145275 | [370] | [354,375,424,430] | 0 | hSpCas9 | negative selection | 5594560 | 142464690 | 142464713 | 8 | + | 27260156 | A673 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.351340762670702 | [286] | [448,445,521,334] | 7 | hSpCas9 | negative selection | 5651525 | 142464427 | 142464450 | 8 | - | 27260156 | A673 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.09377149678388785 | [143] | [121,134,140,250] | -2 | hSpCas9 | negative selection | 5651526 | 142475493 | 142475516 | 8 | - | 27260156 | A673 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.2596323582487965 | [374] | [631,455,409,678] | 6 | hSpCas9 | negative selection | 5651527 | 142475492 | 142475515 | 8 | + | 27260156 | A673 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | 0.2510130868183025 | [124] | [178,136,115,289] | 6 | hSpCas9 | negative selection | 5715809 | 142476685 | 142476708 | 8 | - | 27260156 | A673 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | 0.13935509328934853 | [351] | [561,453,409,445] | 3 | hSpCas9 | negative selection | 5715810 | 142476653 | 142476676 | 8 | + | 27260156 | A673 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.07236635329386665 | [370] | [495,348,333,531] | -2 | hSpCas9 | negative selection | 5715811 | 142464690 | 142464713 | 8 | + | 27260156 | A375 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.08771216461215559 | [286] | [285,147,510,438] | 1 | hSpCas9 | negative selection | 5772776 | 142464427 | 142464450 | 8 | - | 27260156 | A375 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.33095184997226634 | [143] | [164,259,56,76] | -5 | hSpCas9 | negative selection | 5772777 | 142475493 | 142475516 | 8 | - | 27260156 | A375 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.1708676513660497 | [374] | [633,498,408,436] | 2 | hSpCas9 | negative selection | 5772778 | 142475492 | 142475515 | 8 | + | 27260156 | A375 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.4853813015054591 | [124] | [77,264,47,53] | -6 | hSpCas9 | negative selection | 5837060 | 142476685 | 142476708 | 8 | - | 27260156 | A375 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.6927192829131539 | [351] | [351,223,256,187] | -7 | hSpCas9 | negative selection | 5837061 | 142476653 | 142476676 | 8 | + | 27260156 | A375 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.11186749121255549 | [370] | [402,622,524,354] | 1 | hSpCas9 | negative selection | 5837062 | 142464690 | 142464713 | 8 | + | 27260156 | COLO741 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.191601186164168 | [286] | [477,400,383] | 4 | hSpCas9 | negative selection | 5894027 | 142464427 | 142464450 | 8 | - | 27260156 | COLO741 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.03190052960835654 | [143] | [164,133,234] | 0 | hSpCas9 | negative selection | 5894028 | 142475493 | 142475516 | 8 | - | 27260156 | COLO741 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.08671085636707021 | [374] | [659,468,415] | 1 | hSpCas9 | negative selection | 5894029 | 142475492 | 142475515 | 8 | + | 27260156 | COLO741 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | 0.09954468550612505 | [124] | [225,140,151] | 2 | hSpCas9 | negative selection | 5958311 | 142476685 | 142476708 | 8 | - | 27260156 | COLO741 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.04041842287724462 | [351] | [424,433,449] | -1 | hSpCas9 | negative selection | 5958312 | 142476653 | 142476676 | 8 | + | 27260156 | COLO741 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.15099485826748021 | [370] | [655,551,390] | 3 | hSpCas9 | negative selection | 5958313 | 142464690 | 142464713 | 8 | + | 27260156 | CAL120 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.09851237972593252 | [286] | [287,474,369] | 1 | hSpCas9 | negative selection | 6015278 | 142464427 | 142464450 | 8 | - | 27260156 | CAL120 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.467929720522396 | [143] | [107,182,94] | -6 | hSpCas9 | negative selection | 6015279 | 142475493 | 142475516 | 8 | - | 27260156 | CAL120 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.18390072574085217 | [374] | [618,486,497] | 2 | hSpCas9 | negative selection | 6015280 | 142475492 | 142475515 | 8 | + | 27260156 | CAL120 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | 1.0905602349425703 | [124] | [403,237,361] | 9 | hSpCas9 | negative selection | 6079562 | 142476685 | 142476708 | 8 | - | 27260156 | CAL120 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | 0.10263872848220662 | [351] | [509,394,510] | 1 | hSpCas9 | negative selection | 6079563 | 142476653 | 142476676 | 8 | + | 27260156 | CAL120 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.23329397592410178 | [370] | [242,434,475] | -3 | hSpCas9 | negative selection | 6079564 | 142464690 | 142464713 | 8 | + | 27260156 | CADOES1 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | -0.09487691196882486 | [286] | [307,226,177,287] | -2 | hSpCas9 | negative selection | 6136529 | 142464427 | 142464450 | 8 | - | 27260156 | CADOES1 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.831290484571457 | [143] | [110,70,68,48] | -9 | hSpCas9 | negative selection | 6136530 | 142475493 | 142475516 | 8 | - | 27260156 | CADOES1 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.3747951077155871 | [374] | [305,344,206,215] | -6 | hSpCas9 | negative selection | 6136531 | 142475492 | 142475515 | 8 | + | 27260156 | CADOES1 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.1847778601157688 | [124] | [98,81,127,99] | -3 | hSpCas9 | negative selection | 6200813 | 142476685 | 142476708 | 8 | - | 27260156 | CADOES1 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -1.2322259195468965 | [351] | [103,151,149,151] | -9 | hSpCas9 | negative selection | 6200814 | 142476653 | 142476676 | 8 | + | 27260156 | CADOES1 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.06815648223637877 | [370] | [334,407,396,304] | 1 | hSpCas9 | negative selection | 6200815 | 142464690 | 142464713 | 8 | + | 27260156 | EWS502 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.5418081627855076 | [286] | [322,382,560,525] | 8 | hSpCas9 | negative selection | 6257780 | 142464427 | 142464450 | 8 | - | 27260156 | EWS502 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.0970800105215821 | [143] | [132,187,114,131] | -2 | hSpCas9 | negative selection | 6257781 | 142475493 | 142475516 | 8 | - | 27260156 | EWS502 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.054217983056258745 | [374] | [334,389,535,397] | 0 | hSpCas9 | negative selection | 6257782 | 142475492 | 142475515 | 8 | + | 27260156 | EWS502 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | 0.013281325251591092 | [124] | [81,122,180,156] | 0 | hSpCas9 | negative selection | 6322064 | 142476685 | 142476708 | 8 | - | 27260156 | EWS502 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.3389283338529256 | [351] | [172,392,266,359] | -5 | hSpCas9 | negative selection | 6322065 | 142476653 | 142476676 | 8 | + | 27260156 | EWS502 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.058014682669613016 | [370] | [338,445,323,540] | 1 | hSpCas9 | negative selection | 6322066 | 142464690 | 142464713 | 8 | + | 27260156 | EW8 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.7371708989233753 | [286] | [360,350,335,506] | 9 | hSpCas9 | negative selection | 6379031 | 142464427 | 142464450 | 8 | - | 27260156 | EW8 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.40491787960341985 | [143] | [121,89,46,103] | -6 | hSpCas9 | negative selection | 6379032 | 142475493 | 142475516 | 8 | - | 27260156 | EW8 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.46772941557047376 | [374] | [468,470,316,445] | 8 | hSpCas9 | negative selection | 6379033 | 142475492 | 142475515 | 8 | + | 27260156 | EW8 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.1648629260366148 | [124] | [62,69,65,162] | -3 | hSpCas9 | negative selection | 6443315 | 142476685 | 142476708 | 8 | - | 27260156 | EW8 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.20414776450536504 | [351] | [268,273,195,261] | -4 | hSpCas9 | negative selection | 6443316 | 142476653 | 142476676 | 8 | + | 27260156 | EW8 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.03179537953648748 | [370] | [319,204,352,289] | 0 | hSpCas9 | negative selection | 6443317 | 142464690 | 142464713 | 8 | + | 27260156 | CORL105 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.40426471795652197 | [286] | [401,377,551,462] | 7 | hSpCas9 | negative selection | 6500282 | 142464427 | 142464450 | 8 | - | 27260156 | CORL105 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.18910919952824412 | [143] | [166,122,131,167] | -4 | hSpCas9 | negative selection | 6500283 | 142475493 | 142475516 | 8 | - | 27260156 | CORL105 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.04723427641335615 | [374] | [511,399,394,500] | 0 | hSpCas9 | negative selection | 6500284 | 142475492 | 142475515 | 8 | + | 27260156 | CORL105 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.02449696040596261 | [124] | [134,114,152,173] | 0 | hSpCas9 | negative selection | 6564566 | 142476685 | 142476708 | 8 | - | 27260156 | CORL105 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.45008641903435825 | [351] | [262,344,355,248] | -7 | hSpCas9 | negative selection | 6564567 | 142476653 | 142476676 | 8 | + | 27260156 | CORL105 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.2366142750988079 | [370] | [362,252,568,322] | -4 | hSpCas9 | negative selection | 6564568 | 142464690 | 142464713 | 8 | + | 27260156 | HS294T | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.05016307206894277 | [286] | [60,142,111,153] | 0 | hSpCas9 | negative selection | 6621533 | 142464427 | 142464450 | 8 | - | 27260156 | HS294T | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -1.0638093045195125 | [143] | [20,8,43,34] | -9 | hSpCas9 | negative selection | 6621534 | 142475493 | 142475516 | 8 | - | 27260156 | HS294T | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.394228853331841 | [374] | [72,134,98,141] | -5 | hSpCas9 | negative selection | 6621535 | 142475492 | 142475515 | 8 | + | 27260156 | HS294T | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | 0.21274876601774406 | [124] | [25,97,56,41] | 3 | hSpCas9 | negative selection | 6685817 | 142476685 | 142476708 | 8 | - | 27260156 | HS294T | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.9213517454756457 | [351] | [47,34,94,120] | -8 | hSpCas9 | negative selection | 6685818 | 142476653 | 142476676 | 8 | + | 27260156 | HS294T | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.4243064617405637 | [370] | [63,128,113,126] | -6 | hSpCas9 | negative selection | 6685819 | 142464690 | 142464713 | 8 | + | 27260156 | HCC44 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.26212370457427137 | [286] | [358,306,609,326] | 4 | hSpCas9 | negative selection | 6742784 | 142464427 | 142464450 | 8 | - | 27260156 | HCC44 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | 0.06152815997323313 | [143] | [255,107,217,122] | 0 | hSpCas9 | negative selection | 6742785 | 142475493 | 142475516 | 8 | - | 27260156 | HCC44 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.1359577957329801 | [374] | [325,411,431,369] | -2 | hSpCas9 | negative selection | 6742786 | 142475492 | 142475515 | 8 | + | 27260156 | HCC44 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.324637544389319 | [124] | [68,68,117,194] | -5 | hSpCas9 | negative selection | 6807068 | 142476685 | 142476708 | 8 | - | 27260156 | HCC44 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.18579754664097498 | [351] | [384,298,395,335] | -3 | hSpCas9 | negative selection | 6807069 | 142476653 | 142476676 | 8 | + | 27260156 | HCC44 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.13291702748072268 | [370] | [512,558,466,294] | 2 | hSpCas9 | negative selection | 6807070 | 142464690 | 142464713 | 8 | + | 27260156 | G402 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | -0.3771220989236612 | [286] | [357,222,351,159] | -5 | hSpCas9 | negative selection | 6864035 | 142464427 | 142464450 | 8 | - | 27260156 | G402 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.43525320989010896 | [143] | [151,157,81,131] | -5 | hSpCas9 | negative selection | 6864036 | 142475493 | 142475516 | 8 | - | 27260156 | G402 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.07079978800959313 | [374] | [695,421,419,248] | -1 | hSpCas9 | negative selection | 6864037 | 142475492 | 142475515 | 8 | + | 27260156 | G402 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.9705389516483374 | [124] | [19,43,79,152] | -8 | hSpCas9 | negative selection | 6928319 | 142476685 | 142476708 | 8 | - | 27260156 | G402 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -1.1729322293799576 | [351] | [389,206,87,109] | -8 | hSpCas9 | negative selection | 6928320 | 142476653 | 142476676 | 8 | + | 27260156 | G402 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.267703843306816 | [370] | [604,335,292,302] | -3 | hSpCas9 | negative selection | 6928321 | 142464690 | 142464713 | 8 | + | 27260156 | L33 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.48747700449153186 | [286] | [318,161,292,430] | 8 | hSpCas9 | negative selection | 6985286 | 142464427 | 142464450 | 8 | - | 27260156 | L33 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.39255105932915213 | [143] | [85,41,94,99] | -7 | hSpCas9 | negative selection | 6985287 | 142475493 | 142475516 | 8 | - | 27260156 | L33 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.12732428836483725 | [374] | [475,158,288,313] | 3 | hSpCas9 | negative selection | 6985288 | 142475492 | 142475515 | 8 | + | 27260156 | L33 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | 0.25591515982399726 | [124] | [176,54,103,119] | 5 | hSpCas9 | negative selection | 7049570 | 142476685 | 142476708 | 8 | - | 27260156 | L33 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | 0.3752321682953588 | [351] | [522,163,312,403] | 7 | hSpCas9 | negative selection | 7049571 | 142476653 | 142476676 | 8 | + | 27260156 | L33 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.26719797720476984 | [370] | [354,124,180,283] | -6 | hSpCas9 | negative selection | 7049572 | 142464690 | 142464713 | 8 | + | 27260156 | K562 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.044080251535899784 | [286] | [387,317,202,164] | 0 | hSpCas9 | negative selection | 7106537 | 142464427 | 142464450 | 8 | - | 27260156 | K562 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -1.0020401463704973 | [143] | [59,46,56,86] | -8 | hSpCas9 | negative selection | 7106538 | 142475493 | 142475516 | 8 | - | 27260156 | K562 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.20002947405263624 | [374] | [593,284,318,345] | 2 | hSpCas9 | negative selection | 7106539 | 142475492 | 142475515 | 8 | + | 27260156 | K562 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.5999401830715483 | [124] | [70,81,87,53] | -6 | hSpCas9 | negative selection | 7170821 | 142476685 | 142476708 | 8 | - | 27260156 | K562 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | 0.06025221084042487 | [351] | [360,337,129,459] | 0 | hSpCas9 | negative selection | 7170822 | 142476653 | 142476676 | 8 | + | 27260156 | K562 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.31371765473550717 | [370] | [388,253,560,419] | 4 | hSpCas9 | negative selection | 7170823 | 142464690 | 142464713 | 8 | + | 27260156 | HT29 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.5888902504553771 | [286] | [486,636,507,475] | 9 | hSpCas9 | negative selection | 7227788 | 142464427 | 142464450 | 8 | - | 27260156 | HT29 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.38440902156019807 | [143] | [106,190,121,119] | -6 | hSpCas9 | negative selection | 7227789 | 142475493 | 142475516 | 8 | - | 27260156 | HT29 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.13993694745273771 | [374] | [348,464,474,367] | -3 | hSpCas9 | negative selection | 7227790 | 142475492 | 142475515 | 8 | + | 27260156 | HT29 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.6564681229000207 | [124] | [124,95,86,80] | -8 | hSpCas9 | negative selection | 7292072 | 142476685 | 142476708 | 8 | - | 27260156 | HT29 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.39597024674586784 | [351] | [323,357,274,341] | -6 | hSpCas9 | negative selection | 7292073 | 142476653 | 142476676 | 8 | + | 27260156 | HT29 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.21581546214826802 | [370] | [419,313,517,304] | -4 | hSpCas9 | negative selection | 7292074 | 142464690 | 142464713 | 8 | + | 27260156 | MHHES1 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.4255157308241104 | [286] | [474,505,449,331] | 7 | hSpCas9 | negative selection | 7349039 | 142464427 | 142464450 | 8 | - | 27260156 | MHHES1 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.2963123523794502 | [143] | [108,88,160,153] | -5 | hSpCas9 | negative selection | 7349040 | 142475493 | 142475516 | 8 | - | 27260156 | MHHES1 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.2760015579355683 | [374] | [569,683,408,416] | 5 | hSpCas9 | negative selection | 7349041 | 142475492 | 142475515 | 8 | + | 27260156 | MHHES1 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.49086422932334006 | [124] | [108,89,81,113] | -7 | hSpCas9 | negative selection | 7413323 | 142476685 | 142476708 | 8 | - | 27260156 | MHHES1 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.45135061227913426 | [351] | [144,656,264,140] | -7 | hSpCas9 | negative selection | 7413324 | 142476653 | 142476676 | 8 | + | 27260156 | MHHES1 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.2859522078546746 | [370] | [421,624,678,341] | 5 | hSpCas9 | negative selection | 7413325 | 142464690 | 142464713 | 8 | + | 27260156 | MEWO | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.39300523463514275 | [286] | [413,263,391] | 8 | hSpCas9 | negative selection | 7470290 | 142464427 | 142464450 | 8 | - | 27260156 | MEWO | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.26411455773201653 | [143] | [113,86,135] | -5 | hSpCas9 | negative selection | 7470291 | 142475493 | 142475516 | 8 | - | 27260156 | MEWO | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.06491305636986633 | [374] | [485,350,286] | 1 | hSpCas9 | negative selection | 7470292 | 142475492 | 142475515 | 8 | + | 27260156 | MEWO | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | 0.13624510576048632 | [124] | [110,160,109] | 3 | hSpCas9 | negative selection | 7534574 | 142476685 | 142476708 | 8 | - | 27260156 | MEWO | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | 0.29243057318217436 | [351] | [535,313,385] | 6 | hSpCas9 | negative selection | 7534575 | 142476653 | 142476676 | 8 | + | 27260156 | MEWO | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.28707270716759165 | [370] | [276,260,313] | -6 | hSpCas9 | negative selection | 7534576 | 142464690 | 142464713 | 8 | + | 27260156 | LNCAPCLONEFGC | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.38379613170431165 | [286] | [374,242,316,423] | 6 | hSpCas9 | negative selection | 7591541 | 142464427 | 142464450 | 8 | - | 27260156 | LNCAPCLONEFGC | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.12828335754102582 | [143] | [125,89,185,86] | -2 | hSpCas9 | negative selection | 7591542 | 142475493 | 142475516 | 8 | - | 27260156 | LNCAPCLONEFGC | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.2121176150400328 | [374] | [318,198,410,266] | -3 | hSpCas9 | negative selection | 7591543 | 142475492 | 142475515 | 8 | + | 27260156 | LNCAPCLONEFGC | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.0816566245403414 | [124] | [140,81,120,86] | -1 | hSpCas9 | negative selection | 7655825 | 142476685 | 142476708 | 8 | - | 27260156 | LNCAPCLONEFGC | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.5289054902636576 | [351] | [359,126,157,232] | -7 | hSpCas9 | negative selection | 7655826 | 142476653 | 142476676 | 8 | + | 27260156 | LNCAPCLONEFGC | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.027228699028211234 | [370] | [272,218,475,430] | 0 | hSpCas9 | negative selection | 7655827 | 142464690 | 142464713 | 8 | + | 27260156 | PANC0327 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.14156371418410596 | [286] | [146,310,313,337] | 2 | hSpCas9 | negative selection | 7712792 | 142464427 | 142464450 | 8 | - | 27260156 | PANC0327 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.18713197079051058 | [143] | [163,33,234,30] | -3 | hSpCas9 | negative selection | 7712793 | 142475493 | 142475516 | 8 | - | 27260156 | PANC0327 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.32388555662298046 | [374] | [200,268,394,193] | -5 | hSpCas9 | negative selection | 7712794 | 142475492 | 142475515 | 8 | + | 27260156 | PANC0327 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.987174427239871 | [124] | [51,23,131,19] | -8 | hSpCas9 | negative selection | 7777076 | 142476685 | 142476708 | 8 | - | 27260156 | PANC0327 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.7563735185652964 | [351] | [206,68,155,324] | -8 | hSpCas9 | negative selection | 7777077 | 142476653 | 142476676 | 8 | + | 27260156 | PANC0327 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.39534662020198136 | [370] | [487,244,263,764] | 6 | hSpCas9 | negative selection | 7777078 | 142464690 | 142464713 | 8 | + | 27260156 | NCIH2009 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.7977767560966338 | [286] | [930,712,491] | 9 | hSpCas9 | negative selection | 7834043 | 142464427 | 142464450 | 8 | - | 27260156 | NCIH2009 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.7111386502255395 | [143] | [185,64,130] | -7 | hSpCas9 | negative selection | 7834044 | 142475493 | 142475516 | 8 | - | 27260156 | NCIH2009 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.4121064127536564 | [374] | [774,844,482] | 5 | hSpCas9 | negative selection | 7834045 | 142475492 | 142475515 | 8 | + | 27260156 | NCIH2009 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | 0.4706204337861484 | [124] | [118,147,435] | 6 | hSpCas9 | negative selection | 7898327 | 142476685 | 142476708 | 8 | - | 27260156 | NCIH2009 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.42881082290691136 | [351] | [599,298,243] | -5 | hSpCas9 | negative selection | 7898328 | 142476653 | 142476676 | 8 | + | 27260156 | NCIH2009 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.025941263317407537 | [370] | [681,543,333] | 0 | hSpCas9 | negative selection | 7898329 | 142464690 | 142464713 | 8 | + | 27260156 | NCIH1373 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | -0.04146013101619295 | [286] | [431,373,166,75] | 0 | hSpCas9 | negative selection | 7955294 | 142464427 | 142464450 | 8 | - | 27260156 | NCIH1373 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -1.79829847948349 | [143] | [74,41,48,5] | -9 | hSpCas9 | negative selection | 7955295 | 142475493 | 142475516 | 8 | - | 27260156 | NCIH1373 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.28177828615079736 | [374] | [620,185,306,85] | -3 | hSpCas9 | negative selection | 7955296 | 142475492 | 142475515 | 8 | + | 27260156 | NCIH1373 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.6014492642725275 | [124] | [109,28,160,19] | -5 | hSpCas9 | negative selection | 8019578 | 142476685 | 142476708 | 8 | - | 27260156 | NCIH1373 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.9032560419615743 | [351] | [143,194,178,84] | -7 | hSpCas9 | negative selection | 8019579 | 142476653 | 142476676 | 8 | + | 27260156 | NCIH1373 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.43561862153379044 | [370] | [414,222,342,70] | -4 | hSpCas9 | negative selection | 8019580 | 142464690 | 142464713 | 8 | + | 27260156 | PATU8902 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.17357401090830626 | [286] | [110,595,325,851] | 1 | hSpCas9 | negative selection | 8076545 | 142464427 | 142464450 | 8 | - | 27260156 | PATU8902 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -2.345733109546284 | [143] | [7,122,4,29] | -9 | hSpCas9 | negative selection | 8076546 | 142475493 | 142475516 | 8 | - | 27260156 | PATU8902 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.37926088244854284 | [374] | [503,240,517,294] | -4 | hSpCas9 | negative selection | 8076547 | 142475492 | 142475515 | 8 | + | 27260156 | PATU8902 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.6881266902061811 | [124] | [100,127,83,126] | -6 | hSpCas9 | negative selection | 8140829 | 142476685 | 142476708 | 8 | - | 27260156 | PATU8902 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -1.7423560987659994 | [351] | [105,179,121,188] | -8 | hSpCas9 | negative selection | 8140830 | 142476653 | 142476676 | 8 | + | 27260156 | PATU8902 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.35987987915456265 | [370] | [644,760,734,463] | 3 | hSpCas9 | negative selection | 8140831 | 142464690 | 142464713 | 8 | + | 27260156 | PANC1 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | -0.06459796028006914 | [286] | [237,257,196,247] | -1 | hSpCas9 | negative selection | 8197796 | 142464427 | 142464450 | 8 | - | 27260156 | PANC1 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.7424488908082256 | [143] | [110,70,64,49] | -8 | hSpCas9 | negative selection | 8197797 | 142475493 | 142475516 | 8 | - | 27260156 | PANC1 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.013221458119553664 | [374] | [355,409,340,221] | 0 | hSpCas9 | negative selection | 8197798 | 142475492 | 142475515 | 8 | + | 27260156 | PANC1 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.16041503099570598 | [124] | [156,122,81,34] | -3 | hSpCas9 | negative selection | 8262080 | 142476685 | 142476708 | 8 | - | 27260156 | PANC1 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.8267234972653641 | [351] | [212,245,124,117] | -8 | hSpCas9 | negative selection | 8262081 | 142476653 | 142476676 | 8 | + | 27260156 | PANC1 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.2627651325203761 | [370] | [304,240,254,252] | -4 | hSpCas9 | negative selection | 8262082 | 142464690 | 142464713 | 8 | + | 27260156 | PANC0813 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.4355985946259929 | [286] | [402,469,552,395] | 7 | hSpCas9 | negative selection | 8319047 | 142464427 | 142464450 | 8 | - | 27260156 | PANC0813 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -1.058569984853287 | [143] | [62,129,102,29] | -8 | hSpCas9 | negative selection | 8319048 | 142475493 | 142475516 | 8 | - | 27260156 | PANC0813 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.35653976670098364 | [374] | [402,336,402,243] | -5 | hSpCas9 | negative selection | 8319049 | 142475492 | 142475515 | 8 | + | 27260156 | PANC0813 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.2596551422903075 | [124] | [199,122,116,60] | -4 | hSpCas9 | negative selection | 8383331 | 142476685 | 142476708 | 8 | - | 27260156 | PANC0813 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -1.0947033204762622 | [351] | [162,149,116,332] | -8 | hSpCas9 | negative selection | 8383332 | 142476653 | 142476676 | 8 | + | 27260156 | PANC0813 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.2032118056437306 | [370] | [496,524,696,298] | 3 | hSpCas9 | negative selection | 8383333 | 142464690 | 142464713 | 8 | + | 27260156 | RDES | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.38842453194193033 | [286] | [367,333,487,571] | 6 | hSpCas9 | negative selection | 8440298 | 142464427 | 142464450 | 8 | - | 27260156 | RDES | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.2666041206677847 | [143] | [115,92,104,258] | -4 | hSpCas9 | negative selection | 8440299 | 142475493 | 142475516 | 8 | - | 27260156 | RDES | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.1999162126075018 | [374] | [412,599,416,547] | 3 | hSpCas9 | negative selection | 8440300 | 142475492 | 142475515 | 8 | + | 27260156 | RDES | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.17563996113757696 | [124] | [151,104,98,146] | -3 | hSpCas9 | negative selection | 8504582 | 142476685 | 142476708 | 8 | - | 27260156 | RDES | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.487964116036184 | [351] | [219,230,243,502] | -7 | hSpCas9 | negative selection | 8504583 | 142476653 | 142476676 | 8 | + | 27260156 | RDES | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.10137081937537329 | [370] | [297,442,344,527] | -2 | hSpCas9 | negative selection | 8504584 | 142464690 | 142464713 | 8 | + | 27260156 | PC3 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.3019111746573239 | [286] | [286,360,548,270] | 6 | hSpCas9 | negative selection | 8561549 | 142464427 | 142464450 | 8 | - | 27260156 | PC3 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.4491396242405361 | [143] | [88,77,177,98] | -8 | hSpCas9 | negative selection | 8561550 | 142475493 | 142475516 | 8 | - | 27260156 | PC3 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.20190936203662213 | [374] | [303,400,495,559] | 4 | hSpCas9 | negative selection | 8561551 | 142475492 | 142475515 | 8 | + | 27260156 | PC3 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.41660568518790075 | [124] | [54,66,143,138] | -7 | hSpCas9 | negative selection | 8625833 | 142476685 | 142476708 | 8 | - | 27260156 | PC3 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | 0.22375514012728714 | [351] | [284,352,470,574] | 5 | hSpCas9 | negative selection | 8625834 | 142476653 | 142476676 | 8 | + | 27260156 | PC3 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.025859891949929714 | [370] | [283,347,761,255] | 0 | hSpCas9 | negative selection | 8625835 | 142464690 | 142464713 | 8 | + | 27260156 | PATU8988T | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.11908590347751424 | [286] | [264,413,266,266] | 2 | hSpCas9 | negative selection | 8682800 | 142464427 | 142464450 | 8 | - | 27260156 | PATU8988T | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | 0.5789215907302641 | [143] | [165,406,157,111] | 8 | hSpCas9 | negative selection | 8682801 | 142475493 | 142475516 | 8 | - | 27260156 | PATU8988T | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.1986470215385161 | [374] | [461,314,297,176] | -3 | hSpCas9 | negative selection | 8682802 | 142475492 | 142475515 | 8 | + | 27260156 | PATU8988T | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.5560700787745247 | [124] | [29,65,178,47] | -7 | hSpCas9 | negative selection | 8747084 | 142476685 | 142476708 | 8 | - | 27260156 | PATU8988T | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.6566772143825397 | [351] | [231,227,105,306] | -7 | hSpCas9 | negative selection | 8747085 | 142476653 | 142476676 | 8 | + | 27260156 | PATU8988T | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.035871996872980316 | [370] | [343,267,441,408] | 0 | hSpCas9 | negative selection | 8747086 | 142464690 | 142464713 | 8 | + | 27260156 | T47D | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.21415774280242378 | [286] | [372,339,399,443] | 4 | hSpCas9 | negative selection | 8804051 | 142464427 | 142464450 | 8 | - | 27260156 | T47D | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.32549239390600904 | [143] | [144,135,110,143] | -6 | hSpCas9 | negative selection | 8804052 | 142475493 | 142475516 | 8 | - | 27260156 | T47D | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.15070264830737878 | [374] | [476,414,475,580] | 3 | hSpCas9 | negative selection | 8804053 | 142475492 | 142475515 | 8 | + | 27260156 | T47D | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.15440799118659854 | [124] | [107,134,119,160] | -3 | hSpCas9 | negative selection | 8868335 | 142476685 | 142476708 | 8 | - | 27260156 | T47D | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.3385600552593531 | [351] | [287,360,295,349] | -6 | hSpCas9 | negative selection | 8868336 | 142476653 | 142476676 | 8 | + | 27260156 | T47D | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.020752513203534773 | [370] | [438,329,434,510] | 0 | hSpCas9 | negative selection | 8868337 | 142464690 | 142464713 | 8 | + | 27260156 | SU8686 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.581751328935731 | [286] | [320,490,484,404] | 8 | hSpCas9 | negative selection | 8925302 | 142464427 | 142464450 | 8 | - | 27260156 | SU8686 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | 0.05759844489100341 | [143] | [135,159,105,197] | 1 | hSpCas9 | negative selection | 8925303 | 142475493 | 142475516 | 8 | - | 27260156 | SU8686 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | -0.11555867712084622 | [374] | [400,388,270,284] | -2 | hSpCas9 | negative selection | 8925304 | 142475492 | 142475515 | 8 | + | 27260156 | SU8686 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.1349853006539572 | [124] | [84,90,151,132] | -2 | hSpCas9 | negative selection | 8989586 | 142476685 | 142476708 | 8 | - | 27260156 | SU8686 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.45774743473525764 | [351] | [270,253,182,311] | -6 | hSpCas9 | negative selection | 8989587 | 142476653 | 142476676 | 8 | + | 27260156 | SU8686 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.11956666152375864 | [370] | [395,310,405,512] | 2 | hSpCas9 | negative selection | 8989588 | 142464690 | 142464713 | 8 | + | 27260156 | SKES1 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.20316595855637987 | [286] | [215,385,370,331] | 4 | hSpCas9 | negative selection | 9046553 | 142464427 | 142464450 | 8 | - | 27260156 | SKES1 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.4775634717802475 | [143] | [156,94,98,70] | -8 | hSpCas9 | negative selection | 9046554 | 142475493 | 142475516 | 8 | - | 27260156 | SKES1 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.05044064939325671 | [374] | [337,437,456,318] | 1 | hSpCas9 | negative selection | 9046555 | 142475492 | 142475515 | 8 | + | 27260156 | SKES1 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.12056457030488321 | [124] | [129,137,111,85] | -3 | hSpCas9 | negative selection | 9110837 | 142476685 | 142476708 | 8 | - | 27260156 | SKES1 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | 0.05941161578682175 | [351] | [370,405,293,391] | 1 | hSpCas9 | negative selection | 9110838 | 142476653 | 142476676 | 8 | + | 27260156 | SKES1 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.1412651544177267 | [370] | [511,291,318,245] | -3 | hSpCas9 | negative selection | 9110839 | 142464690 | 142464713 | 8 | + | 27260156 | TOV112D | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.3222177389949637 | [286] | [378,420,448,208] | 6 | hSpCas9 | negative selection | 9167804 | 142464427 | 142464450 | 8 | - | 27260156 | TOV112D | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.009627212596509782 | [143] | [117,213,72,181] | 0 | hSpCas9 | negative selection | 9167805 | 142475493 | 142475516 | 8 | - | 27260156 | TOV112D | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.32629178469795567 | [374] | [298,846,528,290] | 6 | hSpCas9 | negative selection | 9167806 | 142475492 | 142475515 | 8 | + | 27260156 | TOV112D | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.8247676344108759 | [124] | [87,110,60,34] | -9 | hSpCas9 | negative selection | 9232088 | 142476685 | 142476708 | 8 | - | 27260156 | TOV112D | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.05868065935770883 | [351] | [332,430,355,257] | -1 | hSpCas9 | negative selection | 9232089 | 142476653 | 142476676 | 8 | + | 27260156 | TOV112D | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | -0.32897644227452233 | [370] | [549,246,238,159] | -6 | hSpCas9 | negative selection | 9232090 | 142464690 | 142464713 | 8 | + | 27260156 | TC71 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.21866334549883465 | [286] | [294,435,292,414] | 5 | hSpCas9 | negative selection | 9289055 | 142464427 | 142464450 | 8 | - | 27260156 | TC71 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.36031050816082755 | [143] | [101,138,113,126] | -7 | hSpCas9 | negative selection | 9289056 | 142475493 | 142475516 | 8 | - | 27260156 | TC71 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.13012297647089582 | [374] | [496,420,377,465] | 3 | hSpCas9 | negative selection | 9289057 | 142475492 | 142475515 | 8 | + | 27260156 | TC71 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.12724195756494705 | [124] | [95,106,113,177] | -3 | hSpCas9 | negative selection | 9353339 | 142476685 | 142476708 | 8 | - | 27260156 | TC71 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | 0.08428921358098213 | [351] | [415,369,405,407] | 2 | hSpCas9 | negative selection | 9353340 | 142476653 | 142476676 | 8 | + | 27260156 | TC71 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.0029552890892330375 | [370] | [551,290,331,418] | 0 | hSpCas9 | negative selection | 9353341 | 142464690 | 142464713 | 8 | + | 27260156 | TC32 | viability | CCCCACCGACGACTTCTCCGTGG | ADGRB1 | ENSG00000181790 | 0.3549905508559247 | [286] | [276,289,454,387] | 6 | hSpCas9 | negative selection | 9410306 | 142464427 | 142464450 | 8 | - | 27260156 | TC32 | viability | ATGTAGAGAGTGTAGCGCCGCGG | ADGRB1 | ENSG00000181790 | -0.11840506218618674 | [143] | [102,131,118,135] | -2 | hSpCas9 | negative selection | 9410307 | 142475493 | 142475516 | 8 | - | 27260156 | TC32 | viability | CCCGCGTGCATTCGCCCCACAGG | ADGRB1 | ENSG00000181790 | 0.23038095412113485 | [374] | [436,365,505,344] | 4 | hSpCas9 | negative selection | 9410308 | 142475492 | 142475515 | 8 | + | 27260156 | TC32 | viability | CCCTGTGGGGCGAATGCACGCGG | ADGRB1 | ENSG00000181790 | -0.818997930102451 | [124] | [59,60,84,61] | -9 | hSpCas9 | negative selection | 9474590 | 142476685 | 142476708 | 8 | - | 27260156 | TC32 | viability | CCGCCAGCTCACCGGTCTGGGGG | ADGRB1 | ENSG00000181790 | -0.3241578337227002 | [351] | [283,200,345,243] | -5 | hSpCas9 | negative selection | 9474591 | 142476653 | 142476676 | 8 | + | 27260156 | TC32 | viability | GGGGACGAGCTGCAGCAGTTTGG | ADGRB1 | ENSG00000181790 | 0.015773045048357803 | [370] | [286,306,562,289] | 0 | hSpCas9 | negative selection | 9474592 |