| 130963041 | 130963064 | 12 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAGGCGTGAGCCACCGCGCCAGG | ADGRD1 | ENSG00000111452 | -0.8581528486253212 | [26,35] | [2,3] | -5 | dCas9-VP64 | positive selection | 2392150 | 131021921 | 131021944 | 12 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGTCTTGAACTCCTGGGCTCAGG | ADGRD1 | ENSG00000111452 | 4.2770735618878515 | [141,50] | [775,15] | 9 | dCas9-VP64 | positive selection | 2397436 | 131121409 | 131121432 | 12 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGAGTCTCACTTTGTCTCCCAGG | ADGRD1 | ENSG00000111452 | -2.7707140657316995 | [68,145] | [2,2] | -9 | dCas9-VP64 | positive selection | 2438753 | 130963041 | 130963064 | 12 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAGGCGTGAGCCACCGCGCCAGG | ADGRD1 | ENSG00000111452 | -0.2201981089703296 | [184,135] | [60,29] | -2 | dCas9-VP64 | positive selection | 2487405 | 131021921 | 131021944 | 12 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGTCTTGAACTCCTGGGCTCAGG | ADGRD1 | ENSG00000111452 | 0.8672449668792414 | [148,204] | [104,104] | 6 | dCas9-VP64 | positive selection | 2492691 | 131121409 | 131121432 | 12 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGAGTCTCACTTTGTCTCCCAGG | ADGRD1 | ENSG00000111452 | 2.5317512356360843 | [92,97] | [219,142] | 9 | dCas9-VP64 | positive selection | 2534008 | 130987225 | 130987248 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CCTGCTCAGACCCTATCACGAGG | ADGRD1 | ENSG00000111452 | 1.49791863876918 | [] | [] | 6 | hSpCas9 | negative selection | 3405086 | 131003175 | 131003198 | 12 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GTTGCTGCAGGACAGCGCCGTGG | ADGRD1 | ENSG00000111452 | 1.76813743523679 | [] | [] | 6 | hSpCas9 | negative selection | 3405087 | 131000379 | 131000402 | 12 | + | 26780180 | HT29 | viability (Avana library 4 designs) | TTAGACCTTCTTAAAAGCCGTGG | ADGRD1 | ENSG00000111452 | 1.79795326928558 | [] | [] | 7 | hSpCas9 | negative selection | 3405088 | 131000379 | 131000402 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | TTAGACCTTCTTAAAAGCCGTGG | ADGRD1 | ENSG00000111452 | 0.904743518295312 | [] | [] | 1 | hSpCas9 | negative selection | 3476930 | 131003175 | 131003198 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GTTGCTGCAGGACAGCGCCGTGG | ADGRD1 | ENSG00000111452 | 4.72999419165864 | [] | [] | 7 | hSpCas9 | negative selection | 3476931 | 130987225 | 130987248 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCTGCTCAGACCCTATCACGAGG | ADGRD1 | ENSG00000111452 | 2.31623400791461 | [] | [] | 3 | hSpCas9 | negative selection | 3476932 | 130982056 | 130982079 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GATGCTGTCACTCACCTGGGGGG | ADGRD1 | ENSG00000111452 | -0.030945797690991 | [] | [] | 0 | hSpCas9 | negative selection | 3476933 | 130987166 | 130987189 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CTGAGCACCTCTGATCCGAGTGG | ADGRD1 | ENSG00000111452 | 4.62624909397088 | [] | [] | 7 | hSpCas9 | negative selection | 3476934 | 131000379 | 131000402 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | TTAGACCTTCTTAAAAGCCGTGG | ADGRD1 | ENSG00000111452 | 8.68215613564547 | [] | [] | 6 | hSpCas9 | negative selection | 3585589 | 131003175 | 131003198 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | GTTGCTGCAGGACAGCGCCGTGG | ADGRD1 | ENSG00000111452 | -1.20633539678325 | [] | [] | -2 | hSpCas9 | negative selection | 3585590 | 130987225 | 130987248 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | CCTGCTCAGACCCTATCACGAGG | ADGRD1 | ENSG00000111452 | 3.02018896553594 | [] | [] | 3 | hSpCas9 | negative selection | 3585591 | 130982056 | 130982079 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | GATGCTGTCACTCACCTGGGGGG | ADGRD1 | ENSG00000111452 | 6.35261509238821 | [] | [] | 5 | hSpCas9 | negative selection | 3585592 | 130987166 | 130987189 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | CTGAGCACCTCTGATCCGAGTGG | ADGRD1 | ENSG00000111452 | -3.22115175927788 | [] | [] | -5 | hSpCas9 | negative selection | 3585593 | 131000379 | 131000402 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | TTAGACCTTCTTAAAAGCCGTGG | ADGRD1 | ENSG00000111452 | -0.0019673388793949864 | [5] | [6,4] | 0 | hSpCas9 | positive selection | 3694248 | 131003175 | 131003198 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GTTGCTGCAGGACAGCGCCGTGG | ADGRD1 | ENSG00000111452 | 0.4140911618918357 | [3] | [5,5] | 9 | hSpCas9 | positive selection | 3694249 | 130987225 | 130987248 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCTGCTCAGACCCTATCACGAGG | ADGRD1 | ENSG00000111452 | -0.28916666746090436 | [4] | [4,2] | -4 | hSpCas9 | positive selection | 3694250 | 130982056 | 130982079 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GATGCTGTCACTCACCTGGGGGG | ADGRD1 | ENSG00000111452 | 0.09640119523281995 | [5] | [6,6] | 2 | hSpCas9 | positive selection | 3694251 | 130987166 | 130987189 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CTGAGCACCTCTGATCCGAGTGG | ADGRD1 | ENSG00000111452 | 0.14761859926665344 | [4] | [5,4] | 4 | hSpCas9 | positive selection | 3694252 | 131000379 | 131000402 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | TTAGACCTTCTTAAAAGCCGTGG | ADGRD1 | ENSG00000111452 | -0.7198255495169857 | [5] | [2,2] | -7 | hSpCas9 | positive selection | 3802855 | 131003175 | 131003198 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GTTGCTGCAGGACAGCGCCGTGG | ADGRD1 | ENSG00000111452 | -1.1096265326092105 | [4] | [2,0] | -8 | hSpCas9 | positive selection | 3802856 | 130987225 | 130987248 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCTGCTCAGACCCTATCACGAGG | ADGRD1 | ENSG00000111452 | 0.24293989148576986 | [4] | [4,3] | 6 | hSpCas9 | positive selection | 3802857 | 130982056 | 130982079 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GATGCTGTCACTCACCTGGGGGG | ADGRD1 | ENSG00000111452 | -0.026137017142514873 | [7] | [5,6] | 0 | hSpCas9 | positive selection | 3802858 | 130987166 | 130987189 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CTGAGCACCTCTGATCCGAGTGG | ADGRD1 | ENSG00000111452 | 0.2441515104204856 | [4] | [4,4] | 6 | hSpCas9 | positive selection | 3802859 | 130954640 | 130954663 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.11943395146680222 | [4] | [2,3] | 3 | hSpCas9 | positive selection | 4140723 | 130971508 | 130971531 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.7299265590885652 | [3] | [1,6] | 9 | hSpCas9 | positive selection | 4140724 | 130954629 | 130954652 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.0554027910855481 | [4] | [2,2] | -1 | hSpCas9 | positive selection | 4140725 | 130954640 | 130954663 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.9074234281888199 | [3] | [3,1,2,3] | 6 | hSpCas9 | positive selection | 4204745 | 130971508 | 130971531 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | -0.006091122784403963 | [3] | [2,3,0,0] | 0 | hSpCas9 | positive selection | 4204746 | 130954629 | 130954652 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.17012320839385722 | [3] | [0,3,0,0] | -2 | hSpCas9 | positive selection | 4204747 | 130987139 | 130987162 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.5528447983741043 | [2] | [3,3] | 9 | hSpCas9 | positive selection | 4273576 | 130954629 | 130954652 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.16302345894509992 | [3] | [3,3] | 3 | hSpCas9 | positive selection | 4273577 | 130987254 | 130987277 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.28348284332264534 | [4] | [5,3] | 6 | hSpCas9 | positive selection | 4273578 | 130954640 | 130954663 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.13400327213897784 | [3] | [2,2] | 2 | hSpCas9 | positive selection | 4337834 | 130971508 | 130971531 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | -0.03146416735973778 | [2] | [2,1] | 0 | hSpCas9 | positive selection | 4337835 | 130971480 | 130971503 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.08361499359798913 | [2] | [2,1] | 1 | hSpCas9 | positive selection | 4337836 | 130987139 | 130987162 | 12 | + | 27260156 | BXPC3 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.42203958025779487 | [454] | [609,615,737,579] | 8 | hSpCas9 | negative selection | 5546036 | 130954629 | 130954652 | 12 | + | 27260156 | BXPC3 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.19324779771163336 | [812] | [670,734,759,820] | -4 | hSpCas9 | negative selection | 5546037 | 130987254 | 130987277 | 12 | - | 27260156 | BXPC3 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.15740595466288343 | [1248] | [1187,1318,1642,1741] | 3 | hSpCas9 | negative selection | 5546038 | 130954640 | 130954663 | 12 | - | 27260156 | BXPC3 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.25716638331357455 | [464] | [540,581,613,588] | 5 | hSpCas9 | negative selection | 5610294 | 130971508 | 130971531 | 12 | + | 27260156 | BXPC3 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.18560336437984587 | [324] | [378,372,332,468] | 4 | hSpCas9 | negative selection | 5610295 | 130971480 | 130971503 | 12 | + | 27260156 | BXPC3 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.19728165224146432 | [249] | [229,306,294,381] | 4 | hSpCas9 | negative selection | 5610296 | 130987139 | 130987162 | 12 | + | 27260156 | A673 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.2682973169365793 | [454] | [687,573,741,629] | 6 | hSpCas9 | negative selection | 5667287 | 130954629 | 130954652 | 12 | + | 27260156 | A673 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.09243434461893041 | [812] | [1053,684,918,1030] | -2 | hSpCas9 | negative selection | 5667288 | 130987254 | 130987277 | 12 | - | 27260156 | A673 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.18727184244405204 | [1248] | [1743,1696,1691,1697] | 4 | hSpCas9 | negative selection | 5667289 | 130954640 | 130954663 | 12 | - | 27260156 | A673 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.023964978595521567 | [464] | [692,464,514,616] | 0 | hSpCas9 | negative selection | 5731545 | 130971508 | 130971531 | 12 | + | 27260156 | A673 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.20219871536540662 | [324] | [428,428,467,467] | 5 | hSpCas9 | negative selection | 5731546 | 130971480 | 130971503 | 12 | + | 27260156 | A673 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.1310150355841917 | [249] | [407,329,256,328] | 3 | hSpCas9 | negative selection | 5731547 | 130987139 | 130987162 | 12 | + | 27260156 | A375 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.18079776099862818 | [454] | [667,773,566,441] | 2 | hSpCas9 | negative selection | 5788538 | 130954629 | 130954652 | 12 | + | 27260156 | A375 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.06419391366499261 | [812] | [1149,875,894,1026] | 0 | hSpCas9 | negative selection | 5788539 | 130987254 | 130987277 | 12 | - | 27260156 | A375 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.46042026385148493 | [1248] | [1780,2586,1843,1900] | 6 | hSpCas9 | negative selection | 5788540 | 130954640 | 130954663 | 12 | - | 27260156 | A375 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.337719697856366 | [464] | [654,901,551,665] | 5 | hSpCas9 | negative selection | 5852796 | 130971508 | 130971531 | 12 | + | 27260156 | A375 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.5444469234629261 | [324] | [600,684,594,371] | 7 | hSpCas9 | negative selection | 5852797 | 130971480 | 130971503 | 12 | + | 27260156 | A375 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.5250801240731158 | [249] | [406,283,658,321] | 7 | hSpCas9 | negative selection | 5852798 | 130987139 | 130987162 | 12 | + | 27260156 | COLO741 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.3491302479493303 | [454] | [939,772,538] | 7 | hSpCas9 | negative selection | 5909789 | 130954629 | 130954652 | 12 | + | 27260156 | COLO741 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.024600960440973263 | [812] | [1042,1046,1074] | 0 | hSpCas9 | negative selection | 5909790 | 130987254 | 130987277 | 12 | - | 27260156 | COLO741 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.31180599278558985 | [1248] | [2226,2021,1728] | 6 | hSpCas9 | negative selection | 5909791 | 130954640 | 130954663 | 12 | - | 27260156 | COLO741 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.2176979067769881 | [464] | [645,988,450] | 4 | hSpCas9 | negative selection | 5974047 | 130971508 | 130971531 | 12 | + | 27260156 | COLO741 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.18092793070938362 | [324] | [548,416,452] | 4 | hSpCas9 | negative selection | 5974048 | 130971480 | 130971503 | 12 | + | 27260156 | COLO741 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | -0.1033581162406495 | [249] | [442,240,224] | -2 | hSpCas9 | negative selection | 5974049 | 130987139 | 130987162 | 12 | + | 27260156 | CAL120 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.1531095091708094 | [454] | [659,542,688] | 2 | hSpCas9 | negative selection | 6031040 | 130954629 | 130954652 | 12 | + | 27260156 | CAL120 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.11004573754669977 | [812] | [1058,938,1268] | 1 | hSpCas9 | negative selection | 6031041 | 130987254 | 130987277 | 12 | - | 27260156 | CAL120 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.44696215186137844 | [1248] | [2358,1726,2301] | 6 | hSpCas9 | negative selection | 6031042 | 130954640 | 130954663 | 12 | - | 27260156 | CAL120 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.3624707577151055 | [464] | [1270,589,454] | 5 | hSpCas9 | negative selection | 6095298 | 130971508 | 130971531 | 12 | + | 27260156 | CAL120 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.2750182242359217 | [324] | [572,671,239] | 4 | hSpCas9 | negative selection | 6095299 | 130971480 | 130971503 | 12 | + | 27260156 | CAL120 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | -0.08909752619944045 | [249] | [371,378,140] | -1 | hSpCas9 | negative selection | 6095300 | 130987139 | 130987162 | 12 | + | 27260156 | CADOES1 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.8276339210581961 | [454] | [620,701,811,873] | 9 | hSpCas9 | negative selection | 6152291 | 130954629 | 130954652 | 12 | + | 27260156 | CADOES1 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.13656225757299922 | [812] | [681,667,696,704] | -2 | hSpCas9 | negative selection | 6152292 | 130987254 | 130987277 | 12 | - | 27260156 | CADOES1 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.39164393880920856 | [1248] | [1319,1608,1501,1670] | 6 | hSpCas9 | negative selection | 6152293 | 130954640 | 130954663 | 12 | - | 27260156 | CADOES1 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.24574764628640483 | [464] | [430,491,444,689] | 4 | hSpCas9 | negative selection | 6216549 | 130971508 | 130971531 | 12 | + | 27260156 | CADOES1 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.012915089903381527 | [324] | [333,291,335,255] | 0 | hSpCas9 | negative selection | 6216550 | 130971480 | 130971503 | 12 | + | 27260156 | CADOES1 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.4162706809337711 | [249] | [268,204,430,336] | 7 | hSpCas9 | negative selection | 6216551 | 130987139 | 130987162 | 12 | + | 27260156 | EWS502 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.3363175588930666 | [454] | [638,479,727,585] | 6 | hSpCas9 | negative selection | 6273542 | 130954629 | 130954652 | 12 | + | 27260156 | EWS502 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.03233040665224707 | [812] | [807,987,648,920] | 0 | hSpCas9 | negative selection | 6273543 | 130987254 | 130987277 | 12 | - | 27260156 | EWS502 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.35485924687024784 | [1248] | [1536,1799,1551,1898] | 6 | hSpCas9 | negative selection | 6273544 | 130954640 | 130954663 | 12 | - | 27260156 | EWS502 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.15464450633565507 | [464] | [492,605,534,561] | 2 | hSpCas9 | negative selection | 6337800 | 130971508 | 130971531 | 12 | + | 27260156 | EWS502 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.14683516391573614 | [324] | [328,387,410,402] | 2 | hSpCas9 | negative selection | 6337801 | 130971480 | 130971503 | 12 | + | 27260156 | EWS502 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.037680629933847465 | [249] | [261,367,262,183] | 0 | hSpCas9 | negative selection | 6337802 | 130987139 | 130987162 | 12 | + | 27260156 | EW8 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.5232177904255972 | [454] | [644,528,350,635] | 8 | hSpCas9 | negative selection | 6394793 | 130954629 | 130954652 | 12 | + | 27260156 | EW8 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.11658906036134364 | [812] | [568,606,557,698] | -2 | hSpCas9 | negative selection | 6394794 | 130987254 | 130987277 | 12 | - | 27260156 | EW8 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.5019543512546436 | [1248] | [1870,1459,1139,1356] | 8 | hSpCas9 | negative selection | 6394795 | 130954640 | 130954663 | 12 | - | 27260156 | EW8 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | -0.18732499282255424 | [464] | [364,262,367,323] | -4 | hSpCas9 | negative selection | 6459051 | 130971508 | 130971531 | 12 | + | 27260156 | EW8 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.10526371366322784 | [324] | [252,336,183,371] | 2 | hSpCas9 | negative selection | 6459052 | 130971480 | 130971503 | 12 | + | 27260156 | EW8 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.13051273140249553 | [249] | [263,148,225,250] | 2 | hSpCas9 | negative selection | 6459053 | 130987139 | 130987162 | 12 | + | 27260156 | CORL105 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.3520182525019568 | [454] | [700,608,997,463] | 6 | hSpCas9 | negative selection | 6516044 | 130954629 | 130954652 | 12 | + | 27260156 | CORL105 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.060051095549452094 | [812] | [902,795,1278,1035] | 1 | hSpCas9 | negative selection | 6516045 | 130987254 | 130987277 | 12 | - | 27260156 | CORL105 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.2811343357685392 | [1248] | [1637,1808,1947,1732] | 5 | hSpCas9 | negative selection | 6516046 | 130954640 | 130954663 | 12 | - | 27260156 | CORL105 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.11312861850700752 | [464] | [509,531,727,604] | 2 | hSpCas9 | negative selection | 6580302 | 130971508 | 130971531 | 12 | + | 27260156 | CORL105 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | -0.45229600653311053 | [324] | [263,206,391,267] | -7 | hSpCas9 | negative selection | 6580303 | 130971480 | 130971503 | 12 | + | 27260156 | CORL105 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.5621946538842892 | [249] | [517,432,402,372] | 8 | hSpCas9 | negative selection | 6580304 | 130987139 | 130987162 | 12 | + | 27260156 | HS294T | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.7896758066012766 | [454] | [410,231,317,234] | 8 | hSpCas9 | negative selection | 6637295 | 130954629 | 130954652 | 12 | + | 27260156 | HS294T | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.18124223542171491 | [812] | [401,442,250,313] | 2 | hSpCas9 | negative selection | 6637296 | 130987254 | 130987277 | 12 | - | 27260156 | HS294T | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.509207662616247 | [1248] | [798,616,477,875] | 6 | hSpCas9 | negative selection | 6637297 | 130954640 | 130954663 | 12 | - | 27260156 | HS294T | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | -0.3063393701856939 | [464] | [121,168,128,165] | -4 | hSpCas9 | negative selection | 6701553 | 130971508 | 130971531 | 12 | + | 27260156 | HS294T | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.6587097050198454 | [324] | [87,455,110,127] | 8 | hSpCas9 | negative selection | 6701554 | 130971480 | 130971503 | 12 | + | 27260156 | HS294T | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.03637509279625939 | [249] | [129,64,81,120] | 0 | hSpCas9 | negative selection | 6701555 | 130987139 | 130987162 | 12 | + | 27260156 | HCC44 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.5307224185479853 | [454] | [688,635,780,873] | 8 | hSpCas9 | negative selection | 6758546 | 130954629 | 130954652 | 12 | + | 27260156 | HCC44 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.1350829396332529 | [812] | [1576,764,992,786] | 2 | hSpCas9 | negative selection | 6758547 | 130987254 | 130987277 | 12 | - | 27260156 | HCC44 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.44101677420657315 | [1248] | [1989,1230,2625,2030] | 7 | hSpCas9 | negative selection | 6758548 | 130954640 | 130954663 | 12 | - | 27260156 | HCC44 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.28799352113971466 | [464] | [811,536,807,470] | 5 | hSpCas9 | negative selection | 6822804 | 130971508 | 130971531 | 12 | + | 27260156 | HCC44 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.616291506297588 | [324] | [519,369,951,499] | 8 | hSpCas9 | negative selection | 6822805 | 130971480 | 130971503 | 12 | + | 27260156 | HCC44 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.5311605101960806 | [249] | [729,340,377,221] | 8 | hSpCas9 | negative selection | 6822806 | 130987139 | 130987162 | 12 | + | 27260156 | G402 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.8457558319557389 | [454] | [961,791,896,1303] | 9 | hSpCas9 | negative selection | 6879797 | 130954629 | 130954652 | 12 | + | 27260156 | G402 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.06814183098429172 | [812] | [1084,879,635,1527] | 0 | hSpCas9 | negative selection | 6879798 | 130987254 | 130987277 | 12 | - | 27260156 | G402 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.06976151259912111 | [1248] | [1807,1599,1158,1842] | 0 | hSpCas9 | negative selection | 6879799 | 130954640 | 130954663 | 12 | - | 27260156 | G402 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.3854529730588325 | [464] | [1040,321,521,1078] | 5 | hSpCas9 | negative selection | 6944055 | 130971508 | 130971531 | 12 | + | 27260156 | G402 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | -0.17703688701104814 | [324] | [344,528,244,294] | -2 | hSpCas9 | negative selection | 6944056 | 130971480 | 130971503 | 12 | + | 27260156 | G402 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.7522850781563044 | [249] | [356,737,545,407] | 8 | hSpCas9 | negative selection | 6944057 | 130987139 | 130987162 | 12 | + | 27260156 | L33 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.5145607362081743 | [454] | [507,369,455,468] | 8 | hSpCas9 | negative selection | 7001048 | 130954629 | 130954652 | 12 | + | 27260156 | L33 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.007693054920531961 | [812] | [863,326,514,786] | 0 | hSpCas9 | negative selection | 7001049 | 130987254 | 130987277 | 12 | - | 27260156 | L33 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.3037881165787055 | [1248] | [1404,641,918,1733] | 6 | hSpCas9 | negative selection | 7001050 | 130954640 | 130954663 | 12 | - | 27260156 | L33 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | -0.16528412408844742 | [464] | [405,162,275,415] | -4 | hSpCas9 | negative selection | 7065306 | 130971508 | 130971531 | 12 | + | 27260156 | L33 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | -0.11767471874677682 | [324] | [250,127,216,290] | -3 | hSpCas9 | negative selection | 7065307 | 130971480 | 130971503 | 12 | + | 27260156 | L33 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.06844164456997459 | [249] | [304,114,148,224] | 1 | hSpCas9 | negative selection | 7065308 | 130987139 | 130987162 | 12 | + | 27260156 | K562 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.3964883387645038 | [454] | [775,476,385,504] | 5 | hSpCas9 | negative selection | 7122299 | 130954629 | 130954652 | 12 | + | 27260156 | K562 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.009072630308258778 | [812] | [337,416,1135,936] | 0 | hSpCas9 | negative selection | 7122300 | 130987254 | 130987277 | 12 | - | 27260156 | K562 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.36273556611015256 | [1248] | [1675,1184,1559,1296] | 4 | hSpCas9 | negative selection | 7122301 | 130954640 | 130954663 | 12 | - | 27260156 | K562 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.22988176188259557 | [464] | [362,772,526,297] | 3 | hSpCas9 | negative selection | 7186557 | 130971508 | 130971531 | 12 | + | 27260156 | K562 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.2974070228412069 | [324] | [414,508,194,314] | 4 | hSpCas9 | negative selection | 7186558 | 130971480 | 130971503 | 12 | + | 27260156 | K562 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | -0.04691209356652981 | [249] | [154,334,177,193] | 0 | hSpCas9 | negative selection | 7186559 | 130987139 | 130987162 | 12 | + | 27260156 | HT29 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.45818915872898675 | [454] | [991,738,747,591] | 8 | hSpCas9 | negative selection | 7243550 | 130954629 | 130954652 | 12 | + | 27260156 | HT29 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.07303450012804102 | [812] | [906,1030,1162,1038] | 1 | hSpCas9 | negative selection | 7243551 | 130987254 | 130987277 | 12 | - | 27260156 | HT29 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.25438666690388256 | [1248] | [1591,2053,1920,1683] | 5 | hSpCas9 | negative selection | 7243552 | 130954640 | 130954663 | 12 | - | 27260156 | HT29 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.30176437495414443 | [464] | [762,766,717,561] | 6 | hSpCas9 | negative selection | 7307808 | 130971508 | 130971531 | 12 | + | 27260156 | HT29 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.1118633473628789 | [324] | [402,452,484,370] | 2 | hSpCas9 | negative selection | 7307809 | 130971480 | 130971503 | 12 | + | 27260156 | HT29 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.01759897644359598 | [249] | [317,302,275,328] | 0 | hSpCas9 | negative selection | 7307810 | 130987139 | 130987162 | 12 | + | 27260156 | MHHES1 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.6001130289567569 | [454] | [1152,726,847,473] | 9 | hSpCas9 | negative selection | 7364801 | 130954629 | 130954652 | 12 | + | 27260156 | MHHES1 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.1919275606060783 | [812] | [1153,1416,1004,712] | 3 | hSpCas9 | negative selection | 7364802 | 130987254 | 130987277 | 12 | - | 27260156 | MHHES1 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.23355426325993434 | [1248] | [2002,1655,1551,1454] | 4 | hSpCas9 | negative selection | 7364803 | 130954640 | 130954663 | 12 | - | 27260156 | MHHES1 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.2939585156447305 | [464] | [920,501,820,389] | 5 | hSpCas9 | negative selection | 7429059 | 130971508 | 130971531 | 12 | + | 27260156 | MHHES1 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | -0.07978754242145525 | [324] | [499,327,470,143] | -1 | hSpCas9 | negative selection | 7429060 | 130971480 | 130971503 | 12 | + | 27260156 | MHHES1 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.2690202425579682 | [249] | [401,451,324,217] | 5 | hSpCas9 | negative selection | 7429061 | 130987139 | 130987162 | 12 | + | 27260156 | MEWO | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.4776459227662756 | [454] | [699,569,528] | 8 | hSpCas9 | negative selection | 7486052 | 130954629 | 130954652 | 12 | + | 27260156 | MEWO | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.07370416705360017 | [812] | [911,772,737] | 1 | hSpCas9 | negative selection | 7486053 | 130987254 | 130987277 | 12 | - | 27260156 | MEWO | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.2025339297183768 | [1248] | [1538,1191,1340] | 4 | hSpCas9 | negative selection | 7486054 | 130954640 | 130954663 | 12 | - | 27260156 | MEWO | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | -0.08679821386327805 | [464] | [489,282,471] | -2 | hSpCas9 | negative selection | 7550310 | 130971508 | 130971531 | 12 | + | 27260156 | MEWO | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.09979912567939525 | [324] | [379,310,296] | 2 | hSpCas9 | negative selection | 7550311 | 130971480 | 130971503 | 12 | + | 27260156 | MEWO | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | -0.14572512253223902 | [249] | [256,219,165] | -3 | hSpCas9 | negative selection | 7550312 | 130987139 | 130987162 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.4941724613988735 | [454] | [527,649,612,531] | 7 | hSpCas9 | negative selection | 7607303 | 130954629 | 130954652 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.02386845112147673 | [812] | [774,522,1045,708] | 0 | hSpCas9 | negative selection | 7607304 | 130987254 | 130987277 | 12 | - | 27260156 | LNCAPCLONEFGC | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.24460320263253155 | [1248] | [1244,1225,1701,1250] | 4 | hSpCas9 | negative selection | 7607305 | 130954640 | 130954663 | 12 | - | 27260156 | LNCAPCLONEFGC | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.020299266750845237 | [464] | [446,352,406,502] | 0 | hSpCas9 | negative selection | 7671561 | 130971508 | 130971531 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.044355708419913764 | [324] | [298,345,313,253] | 0 | hSpCas9 | negative selection | 7671562 | 130971480 | 130971503 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.21633423311542044 | [249] | [255,190,241,364] | 3 | hSpCas9 | negative selection | 7671563 | 130987139 | 130987162 | 12 | + | 27260156 | PANC0327 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.3180685437373683 | [454] | [818,509,251,458] | 5 | hSpCas9 | negative selection | 7728554 | 130954629 | 130954652 | 12 | + | 27260156 | PANC0327 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.28722965863162464 | [812] | [700,483,609,594] | -4 | hSpCas9 | negative selection | 7728555 | 130987254 | 130987277 | 12 | - | 27260156 | PANC0327 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.24148916326893932 | [1248] | [1764,932,1186,1446] | 3 | hSpCas9 | negative selection | 7728556 | 130954640 | 130954663 | 12 | - | 27260156 | PANC0327 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | -0.2758352864304623 | [464] | [348,418,226,359] | -4 | hSpCas9 | negative selection | 7792812 | 130971508 | 130971531 | 12 | + | 27260156 | PANC0327 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.007061505442425564 | [324] | [92,350,170,520] | 0 | hSpCas9 | negative selection | 7792813 | 130971480 | 130971503 | 12 | + | 27260156 | PANC0327 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.31201321530837756 | [249] | [255,283,273,285] | 4 | hSpCas9 | negative selection | 7792814 | 130987139 | 130987162 | 12 | + | 27260156 | NCIH2009 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.5273154532261549 | [454] | [1206,725,874] | 7 | hSpCas9 | negative selection | 7849805 | 130954629 | 130954652 | 12 | + | 27260156 | NCIH2009 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.14431835160506623 | [812] | [1266,1108,1392] | 2 | hSpCas9 | negative selection | 7849806 | 130987254 | 130987277 | 12 | - | 27260156 | NCIH2009 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.3303192178577232 | [1248] | [2831,1944,1931] | 4 | hSpCas9 | negative selection | 7849807 | 130954640 | 130954663 | 12 | - | 27260156 | NCIH2009 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.3997456333400443 | [464] | [759,507,1288] | 5 | hSpCas9 | negative selection | 7914063 | 130971508 | 130971531 | 12 | + | 27260156 | NCIH2009 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.05318833801054601 | [324] | [514,264,644] | 0 | hSpCas9 | negative selection | 7914064 | 130971480 | 130971503 | 12 | + | 27260156 | NCIH2009 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | -0.14324728544004295 | [249] | [369,310,277] | -2 | hSpCas9 | negative selection | 7914065 | 130987139 | 130987162 | 12 | + | 27260156 | NCIH1373 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.3238931137256869 | [454] | [772,860,357,145] | 3 | hSpCas9 | negative selection | 7971056 | 130954629 | 130954652 | 12 | + | 27260156 | NCIH1373 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.05508111031136986 | [812] | [1066,769,805,313] | 0 | hSpCas9 | negative selection | 7971057 | 130987254 | 130987277 | 12 | - | 27260156 | NCIH1373 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.22592075881829876 | [1248] | [1512,1780,1393,481] | 2 | hSpCas9 | negative selection | 7971058 | 130954640 | 130954663 | 12 | - | 27260156 | NCIH1373 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.3268033260581451 | [464] | [754,780,577,128] | 3 | hSpCas9 | negative selection | 8035314 | 130971508 | 130971531 | 12 | + | 27260156 | NCIH1373 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.5064093155557666 | [324] | [614,331,659,128] | 5 | hSpCas9 | negative selection | 8035315 | 130971480 | 130971503 | 12 | + | 27260156 | NCIH1373 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.3593634946618317 | [249] | [197,632,247,78] | 3 | hSpCas9 | negative selection | 8035316 | 130987139 | 130987162 | 12 | + | 27260156 | PATU8902 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.7171364188797413 | [454] | [928,660,1156,1427] | 7 | hSpCas9 | negative selection | 8092307 | 130954629 | 130954652 | 12 | + | 27260156 | PATU8902 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.29956732253831386 | [812] | [1052,1482,915,2354] | 3 | hSpCas9 | negative selection | 8092308 | 130987254 | 130987277 | 12 | - | 27260156 | PATU8902 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.13979321998314953 | [1248] | [2810,1276,1470,2230] | 1 | hSpCas9 | negative selection | 8092309 | 130954640 | 130954663 | 12 | - | 27260156 | PATU8902 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | -0.32807878535769175 | [464] | [422,396,595,637] | -3 | hSpCas9 | negative selection | 8156565 | 130971508 | 130971531 | 12 | + | 27260156 | PATU8902 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | -0.2867809814030867 | [324] | [411,255,395,414] | -3 | hSpCas9 | negative selection | 8156566 | 130971480 | 130971503 | 12 | + | 27260156 | PATU8902 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.5570846185636538 | [249] | [408,518,421,747] | 6 | hSpCas9 | negative selection | 8156567 | 130987139 | 130987162 | 12 | + | 27260156 | PANC1 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.5155378603347218 | [454] | [454,746,585,489] | 8 | hSpCas9 | negative selection | 8213558 | 130954629 | 130954652 | 12 | + | 27260156 | PANC1 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.21976760959534658 | [812] | [459,731,594,626] | -4 | hSpCas9 | negative selection | 8213559 | 130987254 | 130987277 | 12 | - | 27260156 | PANC1 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.25038253160865453 | [1248] | [1074,1719,1369,1051] | 4 | hSpCas9 | negative selection | 8213560 | 130954640 | 130954663 | 12 | - | 27260156 | PANC1 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | -0.41245888690347066 | [464] | [337,429,297,175] | -6 | hSpCas9 | negative selection | 8277816 | 130971508 | 130971531 | 12 | + | 27260156 | PANC1 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.015175500799569086 | [324] | [431,336,171,202] | 0 | hSpCas9 | negative selection | 8277817 | 130971480 | 130971503 | 12 | + | 27260156 | PANC1 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.7329838810836101 | [249] | [337,495,372,259] | 9 | hSpCas9 | negative selection | 8277818 | 130987139 | 130987162 | 12 | + | 27260156 | PANC0813 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.3070185102401876 | [454] | [869,622,759,423] | 5 | hSpCas9 | negative selection | 8334809 | 130954629 | 130954652 | 12 | + | 27260156 | PANC0813 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | 0.1694981666254719 | [812] | [1058,1206,1152,884] | 2 | hSpCas9 | negative selection | 8334810 | 130987254 | 130987277 | 12 | - | 27260156 | PANC0813 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.22291423853653236 | [1248] | [2062,1675,1832,1328] | 3 | hSpCas9 | negative selection | 8334811 | 130954640 | 130954663 | 12 | - | 27260156 | PANC0813 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.018660074859314386 | [464] | [864,422,441,512] | 0 | hSpCas9 | negative selection | 8399067 | 130971508 | 130971531 | 12 | + | 27260156 | PANC0813 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.2205208560631623 | [324] | [353,517,365,526] | 3 | hSpCas9 | negative selection | 8399068 | 130971480 | 130971503 | 12 | + | 27260156 | PANC0813 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.0686296844114822 | [249] | [390,281,243,320] | 1 | hSpCas9 | negative selection | 8399069 | 130987139 | 130987162 | 12 | + | 27260156 | RDES | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.4947204900646468 | [454] | [606,647,803,937] | 7 | hSpCas9 | negative selection | 8456060 | 130954629 | 130954652 | 12 | + | 27260156 | RDES | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.09872087438248456 | [812] | [735,821,875,1100] | -2 | hSpCas9 | negative selection | 8456061 | 130987254 | 130987277 | 12 | - | 27260156 | RDES | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.1921204225751394 | [1248] | [1385,1481,1730,2050] | 3 | hSpCas9 | negative selection | 8456062 | 130954640 | 130954663 | 12 | - | 27260156 | RDES | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.20868350327413104 | [464] | [422,554,674,894] | 3 | hSpCas9 | negative selection | 8520318 | 130971508 | 130971531 | 12 | + | 27260156 | RDES | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.12230398660726371 | [324] | [341,339,426,548] | 2 | hSpCas9 | negative selection | 8520319 | 130971480 | 130971503 | 12 | + | 27260156 | RDES | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.2677666237726323 | [249] | [231,375,360,442] | 4 | hSpCas9 | negative selection | 8520320 | 130987139 | 130987162 | 12 | + | 27260156 | PC3 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.41212273935646426 | [454] | [310,500,1085,797] | 8 | hSpCas9 | negative selection | 8577311 | 130954629 | 130954652 | 12 | + | 27260156 | PC3 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.08639069067998173 | [812] | [503,737,1197,821] | -2 | hSpCas9 | negative selection | 8577312 | 130987254 | 130987277 | 12 | - | 27260156 | PC3 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.35483992902096273 | [1248] | [866,1447,3453,1512] | 7 | hSpCas9 | negative selection | 8577313 | 130954640 | 130954663 | 12 | - | 27260156 | PC3 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.14755353613470376 | [464] | [370,460,614,660] | 3 | hSpCas9 | negative selection | 8641569 | 130971508 | 130971531 | 12 | + | 27260156 | PC3 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | -0.0707219541860693 | [324] | [151,299,572,358] | -1 | hSpCas9 | negative selection | 8641570 | 130971480 | 130971503 | 12 | + | 27260156 | PC3 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.18921501662247286 | [249] | [134,263,652,272] | 4 | hSpCas9 | negative selection | 8641571 | 130987139 | 130987162 | 12 | + | 27260156 | PATU8988T | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.5574729345034962 | [454] | [682,623,525,763] | 8 | hSpCas9 | negative selection | 8698562 | 130954629 | 130954652 | 12 | + | 27260156 | PATU8988T | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.07118482077146282 | [812] | [744,818,759,666] | -1 | hSpCas9 | negative selection | 8698563 | 130987254 | 130987277 | 12 | - | 27260156 | PATU8988T | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.32783401892432407 | [1248] | [1298,1626,1567,1579] | 5 | hSpCas9 | negative selection | 8698564 | 130954640 | 130954663 | 12 | - | 27260156 | PATU8988T | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.026818037576268026 | [464] | [387,310,573,549] | 0 | hSpCas9 | negative selection | 8762820 | 130971508 | 130971531 | 12 | + | 27260156 | PATU8988T | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.16041972366163443 | [324] | [351,378,342,330] | 2 | hSpCas9 | negative selection | 8762821 | 130971480 | 130971503 | 12 | + | 27260156 | PATU8988T | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.8277337366485988 | [249] | [268,748,238,495] | 9 | hSpCas9 | negative selection | 8762822 | 130987139 | 130987162 | 12 | + | 27260156 | T47D | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.3044249606933123 | [454] | [743,592,657,627] | 6 | hSpCas9 | negative selection | 8819813 | 130954629 | 130954652 | 12 | + | 27260156 | T47D | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.23476750404314872 | [812] | [775,712,914,821] | -5 | hSpCas9 | negative selection | 8819814 | 130987254 | 130987277 | 12 | - | 27260156 | T47D | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.29326777326871567 | [1248] | [1775,1763,1724,1871] | 6 | hSpCas9 | negative selection | 8819815 | 130954640 | 130954663 | 12 | - | 27260156 | T47D | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.0071496216573709685 | [464] | [535,442,567,641] | 0 | hSpCas9 | negative selection | 8884071 | 130971508 | 130971531 | 12 | + | 27260156 | T47D | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.054805636549582204 | [324] | [344,424,361,439] | 1 | hSpCas9 | negative selection | 8884072 | 130971480 | 130971503 | 12 | + | 27260156 | T47D | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.18780359858961782 | [249] | [328,344,377,270] | 4 | hSpCas9 | negative selection | 8884073 | 130987139 | 130987162 | 12 | + | 27260156 | SU8686 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.4756464264522178 | [454] | [527,616,607,789] | 7 | hSpCas9 | negative selection | 8941064 | 130954629 | 130954652 | 12 | + | 27260156 | SU8686 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.14735682376209436 | [812] | [686,718,690,829] | -3 | hSpCas9 | negative selection | 8941065 | 130987254 | 130987277 | 12 | - | 27260156 | SU8686 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.3527347534336216 | [1248] | [1177,1605,1740,1884] | 6 | hSpCas9 | negative selection | 8941066 | 130954640 | 130954663 | 12 | - | 27260156 | SU8686 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.04993119907603832 | [464] | [460,370,621,469] | 0 | hSpCas9 | negative selection | 9005322 | 130971508 | 130971531 | 12 | + | 27260156 | SU8686 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.2533292879693469 | [324] | [353,360,382,452] | 4 | hSpCas9 | negative selection | 9005323 | 130971480 | 130971503 | 12 | + | 27260156 | SU8686 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.37423738463038025 | [249] | [288,260,382,370] | 6 | hSpCas9 | negative selection | 9005324 | 130987139 | 130987162 | 12 | + | 27260156 | SKES1 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.3818566587189494 | [454] | [620,717,620,436] | 7 | hSpCas9 | negative selection | 9062315 | 130954629 | 130954652 | 12 | + | 27260156 | SKES1 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.08009708119147585 | [812] | [1011,753,658,679] | -2 | hSpCas9 | negative selection | 9062316 | 130987254 | 130987277 | 12 | - | 27260156 | SKES1 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.27281598026682463 | [1248] | [1695,1659,1428,1291] | 6 | hSpCas9 | negative selection | 9062317 | 130954640 | 130954663 | 12 | - | 27260156 | SKES1 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | -0.1900061284875221 | [464] | [449,504,324,365] | -4 | hSpCas9 | negative selection | 9126573 | 130971508 | 130971531 | 12 | + | 27260156 | SKES1 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.1304262086211901 | [324] | [435,363,303,327] | 3 | hSpCas9 | negative selection | 9126574 | 130971480 | 130971503 | 12 | + | 27260156 | SKES1 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | -0.20240533820453266 | [249] | [248,247,173,203] | -4 | hSpCas9 | negative selection | 9126575 | 130987139 | 130987162 | 12 | + | 27260156 | TOV112D | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.1151623655551593 | [454] | [452,393,439,653] | 2 | hSpCas9 | negative selection | 9183566 | 130954629 | 130954652 | 12 | + | 27260156 | TOV112D | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.020287095734852434 | [812] | [760,896,773,797] | 0 | hSpCas9 | negative selection | 9183567 | 130987254 | 130987277 | 12 | - | 27260156 | TOV112D | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.2958637124363661 | [1248] | [1576,1486,1580,1487] | 5 | hSpCas9 | negative selection | 9183568 | 130954640 | 130954663 | 12 | - | 27260156 | TOV112D | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | -0.03226441750388203 | [464] | [524,441,455,401] | 0 | hSpCas9 | negative selection | 9247824 | 130971508 | 130971531 | 12 | + | 27260156 | TOV112D | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.35611253929872433 | [324] | [507,433,506,233] | 6 | hSpCas9 | negative selection | 9247825 | 130971480 | 130971503 | 12 | + | 27260156 | TOV112D | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.19609664924314163 | [249] | [240,238,209,436] | 4 | hSpCas9 | negative selection | 9247826 | 130987139 | 130987162 | 12 | + | 27260156 | TC71 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.33202532351055686 | [454] | [666,455,686,643] | 7 | hSpCas9 | negative selection | 9304817 | 130954629 | 130954652 | 12 | + | 27260156 | TC71 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.07405059969440153 | [812] | [870,858,743,839] | -2 | hSpCas9 | negative selection | 9304818 | 130987254 | 130987277 | 12 | - | 27260156 | TC71 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.2127897324647101 | [1248] | [1588,1522,1361,1749] | 5 | hSpCas9 | negative selection | 9304819 | 130954640 | 130954663 | 12 | - | 27260156 | TC71 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.001235905752130964 | [464] | [441,598,458,497] | 0 | hSpCas9 | negative selection | 9369075 | 130971508 | 130971531 | 12 | + | 27260156 | TC71 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.3161021847004344 | [324] | [479,447,331,479] | 7 | hSpCas9 | negative selection | 9369076 | 130971480 | 130971503 | 12 | + | 27260156 | TC71 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.14713413236396877 | [249] | [278,330,329,242] | 3 | hSpCas9 | negative selection | 9369077 | 130987139 | 130987162 | 12 | + | 27260156 | TC32 | viability | GGCCTGAAAGTCTACGTCAACGG | ADGRD1 | ENSG00000111452 | 0.44082851171488596 | [454] | [466,384,865,716] | 7 | hSpCas9 | negative selection | 9426068 | 130954629 | 130954652 | 12 | + | 27260156 | TC32 | viability | TGGCGTCTACTCCAGATCGCAGG | ADGRD1 | ENSG00000111452 | -0.053702869926976815 | [812] | [643,518,1062,831] | -1 | hSpCas9 | negative selection | 9426069 | 130987254 | 130987277 | 12 | - | 27260156 | TC32 | viability | AGCACCGTTCTCATAACACTTGG | ADGRD1 | ENSG00000111452 | 0.36253920171155274 | [1248] | [1474,1218,1929,1505] | 6 | hSpCas9 | negative selection | 9426070 | 130954640 | 130954663 | 12 | - | 27260156 | TC32 | viability | ACCTGGATGGTCCTGCGATCTGG | ADGRD1 | ENSG00000111452 | 0.04104168557484922 | [464] | [476,256,684,464] | 0 | hSpCas9 | negative selection | 9490326 | 130971508 | 130971531 | 12 | + | 27260156 | TC32 | viability | GGAGTCACGCTTCTCTATTACGG | ADGRD1 | ENSG00000111452 | 0.21954281206698556 | [324] | [280,274,522,393] | 4 | hSpCas9 | negative selection | 9490327 | 130971480 | 130971503 | 12 | + | 27260156 | TC32 | viability | CAAAGGCATTTACCTGAAAGAGG | ADGRD1 | ENSG00000111452 | 0.34552278339694087 | [249] | [301,236,289,371] | 6 | hSpCas9 | negative selection | 9490328 |