Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:84658
• Symbol:ADGRE3
• Description:adhesion G protein-coupled receptor E3

DataSource: http://genomecrispr.dkfz.de/#!/results/ADGRE3

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
14675087	14675110	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGATTTATTTTGGCCCCAAAGG	ADGRE3	ENSG00000131355	-1.5547334812397209	[371,90]	[15,16]	-8	dCas9-VP64	positive selection	2459879
14675059	14675082	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATCACATTGTCTGAGGATTAGG	ADGRE3	ENSG00000131355	-0.27950208055657466	[614,451]	[45,150]	-1	dCas9-VP64	positive selection	2459880
14675031	14675054	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAGGGCATTTCCTCGTTAGGG	ADGRE3	ENSG00000131355	-0.15662705013750522	[281,59]	[10,56]	0	dCas9-VP64	positive selection	2459881
14675087	14675110	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGATTTATTTTGGCCCCAAAGG	ADGRE3	ENSG00000131355	-0.03004472557389337	[115,172]	[37,52]	0	dCas9-VP64	positive selection	2555134
14675059	14675082	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATCACATTGTCTGAGGATTAGG	ADGRE3	ENSG00000131355	0.8932197573749125	[423,319]	[80,361]	6	dCas9-VP64	positive selection	2555135
14675031	14675054	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAGGGCATTTCCTCGTTAGGG	ADGRE3	ENSG00000131355	0.08180432414197836	[216,228]	[42,107]	0	dCas9-VP64	positive selection	2555136
14658523	14658546	19	-	26780180	HT29	viability (Avana library 4 designs)	ACCTCCTCAAAGACAACCGAGGG	ADGRE3	ENSG00000131355	-0.156848335206225	[]	[]	-3	hSpCas9	negative selection	3405097
14651096	14651119	19	-	26780180	HT29	viability (Avana library 4 designs)	CGTTGCAGTGACATCATCCAGGG	ADGRE3	ENSG00000131355	0.737488376637216	[]	[]	3	hSpCas9	negative selection	3405098
14644225	14644248	19	-	26780180	HT29	viability (Avana library 4 designs)	GTGTCTACTGGAAGAGCACAGGG	ADGRE3	ENSG00000131355	1.97639931553522	[]	[]	7	hSpCas9	negative selection	3405099
14663414	14663437	19	+	26780180	HT29	viability (Avana library 4 designs)	TTACCGTTACATGTCTCCAAGGG	ADGRE3	ENSG00000131355	0.803655204607172	[]	[]	3	hSpCas9	negative selection	3405100
14658523	14658546	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTCCTCAAAGACAACCGAGGG	ADGRE3	ENSG00000131355	-4.91788428173497	[]	[]	-5	hSpCas9	negative selection	3476947
14663414	14663437	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCGTTACATGTCTCCAAGGG	ADGRE3	ENSG00000131355	-8.50528689584771	[]	[]	-7	hSpCas9	negative selection	3476948
14651096	14651119	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTTGCAGTGACATCATCCAGGG	ADGRE3	ENSG00000131355	-0.202769896737684	[]	[]	0	hSpCas9	negative selection	3476949
14644225	14644248	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTCTACTGGAAGAGCACAGGG	ADGRE3	ENSG00000131355	-1.56593117170359	[]	[]	-2	hSpCas9	negative selection	3476950
14663417	14663440	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCCCCTTGGAGACATGTAACGG	ADGRE3	ENSG00000131355	-0.391325183991115	[]	[]	0	hSpCas9	negative selection	3476951
14651097	14651120	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGATGATGTCACTGCAACGG	ADGRE3	ENSG00000131355	1.67301981105617	[]	[]	2	hSpCas9	negative selection	3476952
14658523	14658546	19	-	26780180	A375	viability (Avana lentiGuide)	ACCTCCTCAAAGACAACCGAGGG	ADGRE3	ENSG00000131355	-0.34232273785618	[]	[]	0	hSpCas9	negative selection	3585606
14663414	14663437	19	+	26780180	A375	viability (Avana lentiGuide)	TTACCGTTACATGTCTCCAAGGG	ADGRE3	ENSG00000131355	6.61500704048526	[]	[]	5	hSpCas9	negative selection	3585607
14651096	14651119	19	-	26780180	A375	viability (Avana lentiGuide)	CGTTGCAGTGACATCATCCAGGG	ADGRE3	ENSG00000131355	-5.30637535518111	[]	[]	-8	hSpCas9	negative selection	3585608
14644225	14644248	19	-	26780180	A375	viability (Avana lentiGuide)	GTGTCTACTGGAAGAGCACAGGG	ADGRE3	ENSG00000131355	10.9910403480327	[]	[]	7	hSpCas9	negative selection	3585609
14663417	14663440	19	-	26780180	A375	viability (Avana lentiGuide)	TTCCCCTTGGAGACATGTAACGG	ADGRE3	ENSG00000131355	-2.36723187741335	[]	[]	-4	hSpCas9	negative selection	3585610
14651097	14651120	19	+	26780180	A375	viability (Avana lentiGuide)	CCTGGATGATGTCACTGCAACGG	ADGRE3	ENSG00000131355	6.45709168749362	[]	[]	5	hSpCas9	negative selection	3585611
14658523	14658546	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTCCTCAAAGACAACCGAGGG	ADGRE3	ENSG00000131355	-0.4940692382706283	[4]	[3,2]	-6	hSpCas9	positive selection	3694265
14663414	14663437	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCGTTACATGTCTCCAAGGG	ADGRE3	ENSG00000131355	-0.40480493778701754	[6]	[4,3]	-5	hSpCas9	positive selection	3694266
14651096	14651119	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTTGCAGTGACATCATCCAGGG	ADGRE3	ENSG00000131355	-0.8487973821511718	[3]	[0,2]	-8	hSpCas9	positive selection	3694267
14644225	14644248	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTCTACTGGAAGAGCACAGGG	ADGRE3	ENSG00000131355	-0.04081342091980439	[3]	[3,3]	0	hSpCas9	positive selection	3694268
14663417	14663440	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCCCCTTGGAGACATGTAACGG	ADGRE3	ENSG00000131355	-0.1485232378933038	[5]	[5,4]	-2	hSpCas9	positive selection	3694269
14651097	14651120	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGATGATGTCACTGCAACGG	ADGRE3	ENSG00000131355	-0.03227426892050328	[6]	[5,6]	0	hSpCas9	positive selection	3694270
14658523	14658546	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTCCTCAAAGACAACCGAGGG	ADGRE3	ENSG00000131355	0.193580468974609	[5]	[5,5]	5	hSpCas9	positive selection	3802872
14663414	14663437	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCGTTACATGTCTCCAAGGG	ADGRE3	ENSG00000131355	0.012646664515733458	[6]	[6,3]	0	hSpCas9	positive selection	3802873
14651096	14651119	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTTGCAGTGACATCATCCAGGG	ADGRE3	ENSG00000131355	0.05265010790361034	[4]	[3,4]	1	hSpCas9	positive selection	3802874
14644225	14644248	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTCTACTGGAAGAGCACAGGG	ADGRE3	ENSG00000131355	-0.2657329266049262	[3]	[0,3]	-4	hSpCas9	positive selection	3802875
14663417	14663440	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCCCCTTGGAGACATGTAACGG	ADGRE3	ENSG00000131355	0.3885874330450545	[4]	[5,5]	9	hSpCas9	positive selection	3802876
14651097	14651120	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGATGATGTCACTGCAACGG	ADGRE3	ENSG00000131355	0.17324426853434066	[6]	[6,6]	4	hSpCas9	positive selection	3802877
14663430	14663453	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAACTATTCACATTCCCCTTGG	ADGRE3	ENSG00000131355	0.08074716289613687	[3]	[2,2]	2	hSpCas9	positive selection	4134671
14668811	14668834	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTGAGTCACAGCTCCAAAGAGG	ADGRE3	ENSG00000131355	-0.20808960422206463	[3]	[1,2]	-5	hSpCas9	positive selection	4134672
14668825	14668848	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.018179175426214278	[4]	[3,2]	0	hSpCas9	positive selection	4134673
14663413	14663436	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.011042930521288907	[5]	[4,3]	0	hSpCas9	positive selection	4134674
14663430	14663453	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAACTATTCACATTCCCCTTGG	ADGRE3	ENSG00000131355	-0.2269921528380951	[4]	[0,0,5,0]	-3	hSpCas9	positive selection	4198693
14668811	14668834	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTGAGTCACAGCTCCAAAGAGG	ADGRE3	ENSG00000131355	0.2836667215654824	[3]	[5,0,0,0]	2	hSpCas9	positive selection	4198694
14668825	14668848	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.12141853296723693	[4]	[4,3,0,0]	1	hSpCas9	positive selection	4198695
14663413	14663436	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.8230784397088607	[5]	[3,4,4,3]	5	hSpCas9	positive selection	4198696
14662079	14662102	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.17822265043060698	[3]	[4,2]	3	hSpCas9	positive selection	4268778
14662049	14662072	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.16966990272705	[2]	[2,1]	-3	hSpCas9	positive selection	4268779
14663413	14663436	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.3675036689410049	[4]	[4,4]	7	hSpCas9	positive selection	4268780
14658524	14658547	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.6552997892204149	[2]	[3,3]	9	hSpCas9	positive selection	4333043
14663457	14663480	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	0.24187287171900207	[3]	[3,3]	5	hSpCas9	positive selection	4333044
14668825	14668848	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.5216443960409152	[3]	[4,3]	9	hSpCas9	positive selection	4333045
14662079	14662102	19	-	27260156	BXPC3	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.20925250752029723	[845]	[784,1033,1032,1289]	4	hSpCas9	negative selection	5541238
14662049	14662072	19	-	27260156	BXPC3	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.8442283716093026	[364]	[198,142,243,276]	-9	hSpCas9	negative selection	5541239
14663413	14663436	19	+	27260156	BXPC3	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.0527727694382083	[1193]	[1225,1209,1264,1507]	1	hSpCas9	negative selection	5541240
14658524	14658547	19	-	27260156	BXPC3	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.25366509301892615	[436]	[419,601,526,648]	5	hSpCas9	negative selection	5605503
14663457	14663480	19	+	27260156	BXPC3	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.41056533693843933	[830]	[654,586,694,680]	-7	hSpCas9	negative selection	5605504
14668825	14668848	19	-	27260156	BXPC3	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.35382345412849225	[679]	[865,900,866,1010]	7	hSpCas9	negative selection	5605505
14662079	14662102	19	-	27260156	A673	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.07830004733591944	[845]	[1252,1023,1075,949]	1	hSpCas9	negative selection	5662489
14662049	14662072	19	-	27260156	A673	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.5617223788636452	[364]	[334,310,212,334]	-8	hSpCas9	negative selection	5662490
14663413	14663436	19	+	27260156	A673	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.1263813303167629	[1193]	[1794,1489,1512,1482]	3	hSpCas9	negative selection	5662491
14658524	14658547	19	-	27260156	A673	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.15777932440922382	[436]	[738,589,519,504]	4	hSpCas9	negative selection	5726754
14663457	14663480	19	+	27260156	A673	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.263246200115541	[830]	[777,897,781,859]	-6	hSpCas9	negative selection	5726755
14668825	14668848	19	-	27260156	A673	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.3294862193452752	[679]	[1086,1020,938,1064]	7	hSpCas9	negative selection	5726756
14662079	14662102	19	-	27260156	A375	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.009821142205415856	[845]	[1157,1084,1034,741]	0	hSpCas9	negative selection	5783740
14662049	14662072	19	-	27260156	A375	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-1.26249369982421	[364]	[138,235,128,209]	-8	hSpCas9	negative selection	5783741
14663413	14663436	19	+	27260156	A375	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.05429139342093747	[1193]	[1494,1660,1493,1196]	0	hSpCas9	negative selection	5783742
14658524	14658547	19	-	27260156	A375	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.46561430066808795	[436]	[315,467,305,396]	-6	hSpCas9	negative selection	5848005
14663457	14663480	19	+	27260156	A375	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.6452336262543572	[830]	[757,773,337,630]	-7	hSpCas9	negative selection	5848006
14668825	14668848	19	-	27260156	A375	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.23053811258114598	[679]	[832,1326,944,700]	3	hSpCas9	negative selection	5848007
14662079	14662102	19	-	27260156	COLO741	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.06882103599535527	[845]	[1111,1221,1067]	1	hSpCas9	negative selection	5904991
14662049	14662072	19	-	27260156	COLO741	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.46277994597619954	[364]	[395,379,249]	-7	hSpCas9	negative selection	5904992
14663413	14663436	19	+	27260156	COLO741	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.2603028523660833	[1193]	[1960,1732,1796]	5	hSpCas9	negative selection	5904993
14658524	14658547	19	-	27260156	COLO741	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.117867453950579	[436]	[634,479,442]	-3	hSpCas9	negative selection	5969256
14663457	14663480	19	+	27260156	COLO741	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.40191086995471226	[830]	[875,790,751]	-7	hSpCas9	negative selection	5969257
14668825	14668848	19	-	27260156	COLO741	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.3657550417907063	[679]	[1227,1043,1094]	7	hSpCas9	negative selection	5969258
14662079	14662102	19	-	27260156	CAL120	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.4431038651317699	[845]	[2046,1422,924]	6	hSpCas9	negative selection	6026242
14662049	14662072	19	-	27260156	CAL120	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.06053697525514007	[364]	[251,377,644]	-1	hSpCas9	negative selection	6026243
14663413	14663436	19	+	27260156	CAL120	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.35121952416282687	[1193]	[2074,1726,1909]	5	hSpCas9	negative selection	6026244
14658524	14658547	19	-	27260156	CAL120	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.2402900452768103	[436]	[593,542,779]	3	hSpCas9	negative selection	6090507
14663457	14663480	19	+	27260156	CAL120	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.20094957560472249	[830]	[833,862,989]	-3	hSpCas9	negative selection	6090508
14668825	14668848	19	-	27260156	CAL120	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.21968786169827625	[679]	[1263,881,853]	3	hSpCas9	negative selection	6090509
14662079	14662102	19	-	27260156	CADOES1	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	-0.10362402676839588	[845]	[832,570,806,716]	-2	hSpCas9	negative selection	6147493
14662049	14662072	19	-	27260156	CADOES1	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.45693568181952005	[364]	[241,247,258,239]	-7	hSpCas9	negative selection	6147494
14663413	14663436	19	+	27260156	CADOES1	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.15705855862044538	[1193]	[1031,1321,1042,1568]	2	hSpCas9	negative selection	6147495
14658524	14658547	19	-	27260156	CADOES1	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.0929630796109129	[436]	[306,378,417,421]	-1	hSpCas9	negative selection	6211758
14663457	14663480	19	+	27260156	CADOES1	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.41336543146740007	[830]	[659,509,620,527]	-6	hSpCas9	negative selection	6211759
14668825	14668848	19	-	27260156	CADOES1	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.5086835093649056	[679]	[790,1085,794,928]	8	hSpCas9	negative selection	6211760
14662079	14662102	19	-	27260156	EWS502	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.06651295685094094	[845]	[928,1044,736,1039]	1	hSpCas9	negative selection	6268744
14662049	14662072	19	-	27260156	EWS502	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.779186830005473	[364]	[149,244,311,200]	-8	hSpCas9	negative selection	6268745
14663413	14663436	19	+	27260156	EWS502	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.20190176397138293	[1193]	[1278,1459,1635,1461]	3	hSpCas9	negative selection	6268746
14658524	14658547	19	-	27260156	EWS502	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.17442062122253355	[436]	[398,326,494,424]	-3	hSpCas9	negative selection	6333009
14663457	14663480	19	+	27260156	EWS502	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.6357970519565553	[830]	[375,634,707,566]	-7	hSpCas9	negative selection	6333010
14668825	14668848	19	-	27260156	EWS502	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.32228855652462673	[679]	[769,1031,812,999]	5	hSpCas9	negative selection	6333011
14662079	14662102	19	-	27260156	EW8	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	-0.18603375950003298	[845]	[603,624,549,638]	-4	hSpCas9	negative selection	6389995
14662049	14662072	19	-	27260156	EW8	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-1.1726455397212092	[364]	[173,105,77,179]	-9	hSpCas9	negative selection	6389996
14663413	14663436	19	+	27260156	EW8	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	-0.0009574718215765721	[1193]	[1325,835,886,868]	0	hSpCas9	negative selection	6389997
14658524	14658547	19	-	27260156	EW8	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.0974462675044757	[436]	[317,311,297,398]	-2	hSpCas9	negative selection	6454260
14663457	14663480	19	+	27260156	EW8	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.9520917777983757	[830]	[472,327,307,302]	-9	hSpCas9	negative selection	6454261
14668825	14668848	19	-	27260156	EW8	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.3454990056760484	[679]	[908,782,543,612]	6	hSpCas9	negative selection	6454262
14662079	14662102	19	-	27260156	CORL105	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.13845249695904682	[845]	[900,1022,1283,1176]	2	hSpCas9	negative selection	6511246
14662049	14662072	19	-	27260156	CORL105	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.3073650082656183	[364]	[352,367,369,293]	-5	hSpCas9	negative selection	6511247
14663413	14663436	19	+	27260156	CORL105	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.1733680404422513	[1193]	[1530,1572,1870,1374]	3	hSpCas9	negative selection	6511248
14658524	14658547	19	-	27260156	CORL105	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.024788467460770555	[436]	[530,345,403,717]	0	hSpCas9	negative selection	6575511
14663457	14663480	19	+	27260156	CORL105	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.30788875632685353	[830]	[1075,747,860,481]	-5	hSpCas9	negative selection	6575512
14668825	14668848	19	-	27260156	CORL105	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.24336252658085022	[679]	[967,951,1011,848]	4	hSpCas9	negative selection	6575513
14662079	14662102	19	-	27260156	HS294T	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.672084681348032	[845]	[567,693,366,427]	8	hSpCas9	negative selection	6632497
14662049	14662072	19	-	27260156	HS294T	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.8288145463451415	[364]	[59,65,78,121]	-8	hSpCas9	negative selection	6632498
14663413	14663436	19	+	27260156	HS294T	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.5144081579635713	[1193]	[631,769,619,602]	6	hSpCas9	negative selection	6632499
14658524	14658547	19	-	27260156	HS294T	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.2059514896191782	[436]	[89,223,164,331]	3	hSpCas9	negative selection	6696762
14663457	14663480	19	+	27260156	HS294T	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.7760251555189909	[830]	[144,171,207,237]	-8	hSpCas9	negative selection	6696763
14668825	14668848	19	-	27260156	HS294T	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.3698616576957233	[679]	[349,322,311,378]	5	hSpCas9	negative selection	6696764
14662079	14662102	19	-	27260156	HCC44	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.047391660273528036	[845]	[1194,580,1378,937]	0	hSpCas9	negative selection	6753748
14662049	14662072	19	-	27260156	HCC44	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.647194783488644	[364]	[247,252,205,332]	-7	hSpCas9	negative selection	6753749
14663413	14663436	19	+	27260156	HCC44	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.2176749406116325	[1193]	[1433,1486,1584,1757]	3	hSpCas9	negative selection	6753750
14658524	14658547	19	-	27260156	HCC44	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.14791964983926115	[436]	[534,353,464,450]	-2	hSpCas9	negative selection	6818013
14663457	14663480	19	+	27260156	HCC44	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	0.1467895833333851	[830]	[1145,897,1418,793]	2	hSpCas9	negative selection	6818014
14668825	14668848	19	-	27260156	HCC44	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.2562138940467916	[679]	[934,600,1302,939]	4	hSpCas9	negative selection	6818015
14662079	14662102	19	-	27260156	G402	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.33668036105238797	[845]	[1980,1338,1208,804]	4	hSpCas9	negative selection	6874999
14662049	14662072	19	-	27260156	G402	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-1.1850717499640173	[364]	[130,272,180,192]	-8	hSpCas9	negative selection	6875000
14663413	14663436	19	+	27260156	G402	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.10911390430280421	[1193]	[2142,1364,1482,1368]	1	hSpCas9	negative selection	6875001
14658524	14658547	19	-	27260156	G402	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.17057120195438846	[436]	[307,701,386,484]	-2	hSpCas9	negative selection	6939264
14663457	14663480	19	+	27260156	G402	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.5021465326735182	[830]	[479,559,959,812]	-6	hSpCas9	negative selection	6939265
14668825	14668848	19	-	27260156	G402	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.7221138868424373	[679]	[1473,1091,1221,1665]	8	hSpCas9	negative selection	6939266
14662079	14662102	19	-	27260156	L33	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.4940689982867753	[845]	[1391,411,762,1149]	8	hSpCas9	negative selection	6996250
14662049	14662072	19	-	27260156	L33	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.4826419958109508	[364]	[191,129,137,316]	-8	hSpCas9	negative selection	6996251
14663413	14663436	19	+	27260156	L33	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.5114945251004308	[1193]	[1702,736,988,1731]	8	hSpCas9	negative selection	6996252
14658524	14658547	19	-	27260156	L33	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.26391737416730715	[436]	[562,202,402,399]	5	hSpCas9	negative selection	7060515
14663457	14663480	19	+	27260156	L33	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.12208912015350193	[830]	[840,293,448,778]	-3	hSpCas9	negative selection	7060516
14668825	14668848	19	-	27260156	L33	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	-0.17808781679747238	[679]	[669,205,347,674]	-4	hSpCas9	negative selection	7060517
14662079	14662102	19	-	27260156	K562	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.49314420334293085	[845]	[1165,1458,1000,671]	6	hSpCas9	negative selection	7117501
14662049	14662072	19	-	27260156	K562	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.4260932674014165	[364]	[165,282,67,420]	-5	hSpCas9	negative selection	7117502
14663413	14663436	19	+	27260156	K562	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	-0.019934655153915903	[1193]	[889,799,1290,1155]	0	hSpCas9	negative selection	7117503
14658524	14658547	19	-	27260156	K562	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.021007315097862106	[436]	[442,324,224,559]	0	hSpCas9	negative selection	7181766
14663457	14663480	19	+	27260156	K562	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.27274775575770627	[830]	[769,484,574,614]	-3	hSpCas9	negative selection	7181767
14668825	14668848	19	-	27260156	K562	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.29004251966193517	[679]	[966,868,533,617]	3	hSpCas9	negative selection	7181768
14662079	14662102	19	-	27260156	HT29	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.0547037641992818	[845]	[1082,1387,1010,839]	1	hSpCas9	negative selection	7238752
14662049	14662072	19	-	27260156	HT29	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.5423004331550421	[364]	[298,454,125,343]	-7	hSpCas9	negative selection	7238753
14663413	14663436	19	+	27260156	HT29	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.26766517283287006	[1193]	[1763,1896,1701,1640]	5	hSpCas9	negative selection	7238754
14658524	14658547	19	-	27260156	HT29	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.20484593530352158	[436]	[677,600,649,529]	4	hSpCas9	negative selection	7303017
14663457	14663480	19	+	27260156	HT29	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.23595641525931133	[830]	[753,1182,840,687]	-5	hSpCas9	negative selection	7303018
14668825	14668848	19	-	27260156	HT29	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.4326013809948459	[679]	[1306,1123,1022,1026]	8	hSpCas9	negative selection	7303019
14662079	14662102	19	-	27260156	MHHES1	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.4301090098699093	[845]	[1337,1624,1267,985]	7	hSpCas9	negative selection	7360003
14662049	14662072	19	-	27260156	MHHES1	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.47924389497556785	[364]	[453,261,268,220]	-7	hSpCas9	negative selection	7360004
14663413	14663436	19	+	27260156	MHHES1	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.19707006196420984	[1193]	[1260,1585,1940,1358]	3	hSpCas9	negative selection	7360005
14658524	14658547	19	-	27260156	MHHES1	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.08137246633712154	[436]	[531,534,391,416]	-1	hSpCas9	negative selection	7424268
14663457	14663480	19	+	27260156	MHHES1	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.2980065215417357	[830]	[800,1067,693,549]	-5	hSpCas9	negative selection	7424269
14668825	14668848	19	-	27260156	MHHES1	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.3097996149259402	[679]	[1263,831,911,822]	5	hSpCas9	negative selection	7424270
14662079	14662102	19	-	27260156	MEWO	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.23687041396285868	[845]	[1034,880,901]	5	hSpCas9	negative selection	7481254
14662049	14662072	19	-	27260156	MEWO	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.4223714808621789	[364]	[267,240,257]	-7	hSpCas9	negative selection	7481255
14663413	14663436	19	+	27260156	MEWO	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.3093519702061782	[1193]	[1690,1127,1393]	6	hSpCas9	negative selection	7481256
14658524	14658547	19	-	27260156	MEWO	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.15396042527911308	[436]	[628,307,461]	3	hSpCas9	negative selection	7545519
14663457	14663480	19	+	27260156	MEWO	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	0.09460986681120376	[830]	[796,794,891]	2	hSpCas9	negative selection	7545520
14668825	14668848	19	-	27260156	MEWO	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.09428855925254809	[679]	[734,702,609]	2	hSpCas9	negative selection	7545521
14662079	14662102	19	-	27260156	LNCAPCLONEFGC	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.21413912185781092	[845]	[891,741,996,949]	3	hSpCas9	negative selection	7602505
14662049	14662072	19	-	27260156	LNCAPCLONEFGC	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.46391001725558534	[364]	[250,237,174,284]	-6	hSpCas9	negative selection	7602506
14663413	14663436	19	+	27260156	LNCAPCLONEFGC	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.13958734835356879	[1193]	[1116,1201,1158,1282]	2	hSpCas9	negative selection	7602507
14658524	14658547	19	-	27260156	LNCAPCLONEFGC	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.2914908191289927	[436]	[351,339,303,292]	-4	hSpCas9	negative selection	7666770
14663457	14663480	19	+	27260156	LNCAPCLONEFGC	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.43487034069055824	[830]	[501,525,595,611]	-6	hSpCas9	negative selection	7666771
14668825	14668848	19	-	27260156	LNCAPCLONEFGC	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.4213935435233661	[679]	[772,707,1121,748]	6	hSpCas9	negative selection	7666772
14662079	14662102	19	-	27260156	PANC0327	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	-0.21475646634925338	[845]	[532,609,885,556]	-3	hSpCas9	negative selection	7723756
14662049	14662072	19	-	27260156	PANC0327	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-1.5696868178433496	[364]	[111,100,39,184]	-9	hSpCas9	negative selection	7723757
14663413	14663436	19	+	27260156	PANC0327	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.0026768133353383128	[1193]	[876,733,1079,1585]	0	hSpCas9	negative selection	7723758
14658524	14658547	19	-	27260156	PANC0327	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.11327665268574534	[436]	[297,264,604,274]	-2	hSpCas9	negative selection	7788021
14663457	14663480	19	+	27260156	PANC0327	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.585755608860191	[830]	[464,501,601,394]	-7	hSpCas9	negative selection	7788022
14668825	14668848	19	-	27260156	PANC0327	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.22966479330403433	[679]	[747,745,551,784]	3	hSpCas9	negative selection	7788023
14662079	14662102	19	-	27260156	NCIH2009	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.5463944784424678	[845]	[1849,1571,1780]	7	hSpCas9	negative selection	7845007
14662049	14662072	19	-	27260156	NCIH2009	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.5561273018196341	[364]	[404,314,331]	-6	hSpCas9	negative selection	7845008
14663413	14663436	19	+	27260156	NCIH2009	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.35155289240964804	[1193]	[2466,2119,1861]	5	hSpCas9	negative selection	7845009
14658524	14658547	19	-	27260156	NCIH2009	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.1560013896783215	[436]	[678,542,446]	-2	hSpCas9	negative selection	7909272
14663457	14663480	19	+	27260156	NCIH2009	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.34755707564403593	[830]	[1077,834,856]	-5	hSpCas9	negative selection	7909273
14668825	14668848	19	-	27260156	NCIH2009	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.4671895485826494	[679]	[1234,1226,1461]	6	hSpCas9	negative selection	7909274
14662079	14662102	19	-	27260156	NCIH1373	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.22777495535905146	[845]	[995,985,1147,344]	2	hSpCas9	negative selection	7966258
14662049	14662072	19	-	27260156	NCIH1373	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-1.5863699050499143	[364]	[214,48,181,30]	-9	hSpCas9	negative selection	7966259
14663413	14663436	19	+	27260156	NCIH1373	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.048636930918374066	[1193]	[1463,1130,1101,501]	0	hSpCas9	negative selection	7966260
14658524	14658547	19	-	27260156	NCIH1373	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.4970518193055936	[436]	[309,382,424,65]	-5	hSpCas9	negative selection	8030523
14663457	14663480	19	+	27260156	NCIH1373	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.6787601180627011	[830]	[850,296,598,171]	-6	hSpCas9	negative selection	8030524
14668825	14668848	19	-	27260156	NCIH1373	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.8124045127613106	[679]	[1260,1778,1174,277]	7	hSpCas9	negative selection	8030525
14662079	14662102	19	-	27260156	PATU8902	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	-0.8592428023133951	[845]	[592,749,271,1134]	-7	hSpCas9	negative selection	8087509
14662049	14662072	19	-	27260156	PATU8902	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-2.6493067722577717	[364]	[46,24,161,66]	-9	hSpCas9	negative selection	8087510
14663413	14663436	19	+	27260156	PATU8902	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	-0.13449834261068894	[1193]	[1316,1794,986,2166]	-1	hSpCas9	negative selection	8087511
14658524	14658547	19	-	27260156	PATU8902	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.7506620954712117	[436]	[202,334,493,381]	-6	hSpCas9	negative selection	8151774
14663457	14663480	19	+	27260156	PATU8902	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.8345318386180773	[830]	[854,363,726,616]	-7	hSpCas9	negative selection	8151775
14668825	14668848	19	-	27260156	PATU8902	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.5721695455256455	[679]	[1844,1442,1130,1248]	6	hSpCas9	negative selection	8151776
14662079	14662102	19	-	27260156	PANC1	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.1935604882483496	[845]	[824,1079,818,664]	3	hSpCas9	negative selection	8208760
14662049	14662072	19	-	27260156	PANC1	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-1.0369656298490433	[364]	[185,190,110,130]	-8	hSpCas9	negative selection	8208761
14663413	14663436	19	+	27260156	PANC1	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.34430528666173266	[1193]	[1336,1516,1577,871]	5	hSpCas9	negative selection	8208762
14658524	14658547	19	-	27260156	PANC1	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.09877678256178347	[436]	[286,467,372,301]	-2	hSpCas9	negative selection	8273025
14663457	14663480	19	+	27260156	PANC1	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.6832227636031072	[830]	[434,526,240,562]	-7	hSpCas9	negative selection	8273026
14668825	14668848	19	-	27260156	PANC1	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.31941744507000003	[679]	[802,897,509,723]	5	hSpCas9	negative selection	8273027
14662079	14662102	19	-	27260156	PANC0813	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.3450085239657855	[845]	[1198,1171,1413,1256]	5	hSpCas9	negative selection	8330011
14662049	14662072	19	-	27260156	PANC0813	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.5688842336320034	[364]	[361,373,211,217]	-7	hSpCas9	negative selection	8330012
14663413	14663436	19	+	27260156	PANC0813	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.295855149803512	[1193]	[1690,1739,1602,1839]	5	hSpCas9	negative selection	8330013
14658524	14658547	19	-	27260156	PANC0813	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.14269080299841752	[436]	[463,285,695,416]	-2	hSpCas9	negative selection	8394276
14663457	14663480	19	+	27260156	PANC0813	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.5690269458925112	[830]	[773,545,583,732]	-7	hSpCas9	negative selection	8394277
14668825	14668848	19	-	27260156	PANC0813	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.12284573730205217	[679]	[996,865,1085,558]	2	hSpCas9	negative selection	8394278
14662079	14662102	19	-	27260156	RDES	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	-0.10674468562612804	[845]	[727,700,811,1490]	-2	hSpCas9	negative selection	8451262
14662049	14662072	19	-	27260156	RDES	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.7643514833071756	[364]	[196,179,340,290]	-8	hSpCas9	negative selection	8451263
14663413	14663436	19	+	27260156	RDES	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.27236369725686904	[1193]	[1352,1687,1669,1984]	4	hSpCas9	negative selection	8451264
14658524	14658547	19	-	27260156	RDES	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.009653436643485891	[436]	[391,428,475,785]	0	hSpCas9	negative selection	8515527
14663457	14663480	19	+	27260156	RDES	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.3283501955699316	[830]	[668,661,766,986]	-5	hSpCas9	negative selection	8515528
14668825	14668848	19	-	27260156	RDES	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.5614492695650866	[679]	[1012,909,1313,1448]	8	hSpCas9	negative selection	8515529
14662079	14662102	19	-	27260156	PC3	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.014436412812216637	[845]	[498,767,1430,1023]	0	hSpCas9	negative selection	8572513
14662049	14662072	19	-	27260156	PC3	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.8781596679157762	[364]	[122,164,417,186]	-9	hSpCas9	negative selection	8572514
14663413	14663436	19	+	27260156	PC3	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.2777397899138925	[1193]	[961,1237,2225,1737]	6	hSpCas9	negative selection	8572515
14658524	14658547	19	-	27260156	PC3	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.10933376395731224	[436]	[238,536,915,417]	2	hSpCas9	negative selection	8636778
14663457	14663480	19	+	27260156	PC3	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.3394928505201767	[830]	[401,743,953,677]	-6	hSpCas9	negative selection	8636779
14668825	14668848	19	-	27260156	PC3	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.18673979377851546	[679]	[616,699,948,870]	4	hSpCas9	negative selection	8636780
14662079	14662102	19	-	27260156	PATU8988T	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.31781745148586393	[845]	[1031,936,1011,1092]	5	hSpCas9	negative selection	8693764
14662049	14662072	19	-	27260156	PATU8988T	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.4679521440017912	[364]	[289,124,254,344]	-6	hSpCas9	negative selection	8693765
14663413	14663436	19	+	27260156	PATU8988T	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.21570147918221805	[1193]	[1277,1431,1493,1145]	4	hSpCas9	negative selection	8693766
14658524	14658547	19	-	27260156	PATU8988T	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.11223387129986497	[436]	[289,430,399,449]	-2	hSpCas9	negative selection	8758029
14663457	14663480	19	+	27260156	PATU8988T	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.45937885978243154	[830]	[366,664,691,620]	-6	hSpCas9	negative selection	8758030
14668825	14668848	19	-	27260156	PATU8988T	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.3414426793923524	[679]	[892,1019,621,813]	6	hSpCas9	negative selection	8758031
14662079	14662102	19	-	27260156	T47D	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.08059024269411874	[845]	[953,1092,1096,1017]	1	hSpCas9	negative selection	8815015
14662049	14662072	19	-	27260156	T47D	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.5351427891988495	[364]	[329,290,250,302]	-8	hSpCas9	negative selection	8815016
14663413	14663436	19	+	27260156	T47D	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.15846082577467313	[1193]	[1567,1533,1657,1445]	3	hSpCas9	negative selection	8815017
14658524	14658547	19	-	27260156	T47D	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.1594436209061736	[436]	[478,373,507,468]	-4	hSpCas9	negative selection	8879280
14663457	14663480	19	+	27260156	T47D	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.43594857037495643	[830]	[646,736,747,727]	-7	hSpCas9	negative selection	8879281
14668825	14668848	19	-	27260156	T47D	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.2595363374789663	[679]	[1052,944,955,835]	5	hSpCas9	negative selection	8879282
14662079	14662102	19	-	27260156	SU8686	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.5611383511142994	[845]	[1173,1283,1191,1300]	8	hSpCas9	negative selection	8936266
14662049	14662072	19	-	27260156	SU8686	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-1.1149319938739395	[364]	[88,146,245,204]	-8	hSpCas9	negative selection	8936267
14663413	14663436	19	+	27260156	SU8686	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.16301290977078575	[1193]	[1136,1144,1704,1366]	2	hSpCas9	negative selection	8936268
14658524	14658547	19	-	27260156	SU8686	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.3239956752226104	[436]	[228,316,297,593]	-5	hSpCas9	negative selection	9000531
14663457	14663480	19	+	27260156	SU8686	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.2839139686051986	[830]	[596,529,579,1086]	-5	hSpCas9	negative selection	9000532
14668825	14668848	19	-	27260156	SU8686	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.2824477717899422	[679]	[696,824,834,951]	5	hSpCas9	negative selection	9000533
14662079	14662102	19	-	27260156	SKES1	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	-0.015499988394478081	[845]	[916,972,819,668]	0	hSpCas9	negative selection	9057517
14662049	14662072	19	-	27260156	SKES1	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.8644467164878669	[364]	[264,185,146,206]	-9	hSpCas9	negative selection	9057518
14663413	14663436	19	+	27260156	SKES1	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.13301940053397066	[1193]	[1676,1197,1371,1033]	3	hSpCas9	negative selection	9057519
14658524	14658547	19	-	27260156	SKES1	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.2885784164227017	[436]	[709,499,366,565]	6	hSpCas9	negative selection	9121782
14663457	14663480	19	+	27260156	SKES1	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.28778398889284607	[830]	[953,632,558,605]	-6	hSpCas9	negative selection	9121783
14668825	14668848	19	-	27260156	SKES1	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.29026010095649946	[679]	[935,1025,744,661]	6	hSpCas9	negative selection	9121784
14662079	14662102	19	-	27260156	TOV112D	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	-0.00044289070622038906	[845]	[826,1223,837,595]	0	hSpCas9	negative selection	9178768
14662049	14662072	19	-	27260156	TOV112D	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.474152225538109	[364]	[406,153,340,138]	-7	hSpCas9	negative selection	9178769
14663413	14663436	19	+	27260156	TOV112D	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.26851333160410995	[1193]	[1611,1946,1274,1074]	5	hSpCas9	negative selection	9178770
14658524	14658547	19	-	27260156	TOV112D	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.04121019441336472	[436]	[571,479,230,442]	-1	hSpCas9	negative selection	9243033
14663457	14663480	19	+	27260156	TOV112D	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.14839570942469815	[830]	[683,542,797,915]	-3	hSpCas9	negative selection	9243034
14668825	14668848	19	-	27260156	TOV112D	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.0366152249354843	[679]	[744,686,766,597]	0	hSpCas9	negative selection	9243035
14662079	14662102	19	-	27260156	TC71	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.09398006205072573	[845]	[1098,796,798,1192]	2	hSpCas9	negative selection	9300019
14662049	14662072	19	-	27260156	TC71	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.5512944010252123	[364]	[317,243,285,214]	-9	hSpCas9	negative selection	9300020
14663413	14663436	19	+	27260156	TC71	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.26127415906397	[1193]	[1504,1669,1429,1534]	6	hSpCas9	negative selection	9300021
14658524	14658547	19	-	27260156	TC71	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	0.006023648607126647	[436]	[314,469,484,623]	0	hSpCas9	negative selection	9364284
14663457	14663480	19	+	27260156	TC71	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.18934872828149463	[830]	[847,683,653,951]	-5	hSpCas9	negative selection	9364285
14668825	14668848	19	-	27260156	TC71	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.2602977237452714	[679]	[945,794,869,879]	6	hSpCas9	negative selection	9364286
14662079	14662102	19	-	27260156	TC32	viability	CCACCCTATAGTGTATATTGTGG	ADGRE3	ENSG00000131355	0.015134775955547797	[845]	[876,531,991,895]	0	hSpCas9	negative selection	9421270
14662049	14662072	19	-	27260156	TC32	viability	GCTGTGTGTTACAATGTCGAAGG	ADGRE3	ENSG00000131355	-0.596208628185711	[364]	[186,218,229,267]	-8	hSpCas9	negative selection	9421271
14663413	14663436	19	+	27260156	TC32	viability	TTTACCGTTACATGTCTCCAAGG	ADGRE3	ENSG00000131355	0.44792990802448096	[1193]	[1383,1459,1679,1572]	7	hSpCas9	negative selection	9421272
14658524	14658547	19	-	27260156	TC32	viability	CACCTCCTCAAAGACAACCGAGG	ADGRE3	ENSG00000131355	-0.2128093688146887	[436]	[266,329,391,437]	-4	hSpCas9	negative selection	9485535
14663457	14663480	19	+	27260156	TC32	viability	CAGATCCAGAAGTATATCCATGG	ADGRE3	ENSG00000131355	-0.3802802938385926	[830]	[469,623,738,556]	-6	hSpCas9	negative selection	9485536
14668825	14668848	19	-	27260156	TC32	viability	TGCTTTCTGCTGAGCCTCTTTGG	ADGRE3	ENSG00000131355	0.6312285961883486	[679]	[888,743,1376,1067]	9	hSpCas9	negative selection	9485537