Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:134
• Symbol:ADORA1
• Description:adenosine A1 receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/ADORA1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
203129032	203129055	1	-	26472758	Jiyoye	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	-0.1561571032437401	[330]	[223]	-1	hSpCas9	negative selection	3343
203129092	203129115	1	-	26472758	Jiyoye	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-1.5277295902722419	[64]	[16]	-7	hSpCas9	negative selection	3344
203129159	203129182	1	-	26472758	Jiyoye	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.48809537688944066	[155]	[164]	3	hSpCas9	negative selection	3345
203128849	203128872	1	-	26472758	Jiyoye	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.13691483779975466	[260]	[178]	-1	hSpCas9	negative selection	3346
203128942	203128965	1	+	26472758	Jiyoye	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	1.8666070001431707	[15]	[43]	8	hSpCas9	negative selection	3347
203128969	203128992	1	-	26472758	Jiyoye	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	1.4255539108207282	[116]	[236]	8	hSpCas9	negative selection	3348
203129011	203129034	1	-	26472758	Jiyoye	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-0.6802874597444659	[16]	[7]	-5	hSpCas9	negative selection	3349
203129081	203129104	1	-	26472758	Jiyoye	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.10232079997745264	[146]	[118]	0	hSpCas9	negative selection	3350
203128919	203128942	1	+	26472758	Jiyoye	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	-1.0522562371314237	[153]	[55]	-6	hSpCas9	negative selection	3351
203128995	203129018	1	+	26472758	Jiyoye	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	-1.0038932155700249	[241]	[90]	-6	hSpCas9	negative selection	3352
203129032	203129055	1	-	26472758	KBM7	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.1856070592537834	[1033,814]	[475,503]	2	hSpCas9	negative selection	194461
203129092	203129115	1	-	26472758	KBM7	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	0.08778106631076255	[167,107]	[43,88]	0	hSpCas9	negative selection	194462
203129159	203129182	1	-	26472758	KBM7	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.45672151847315834	[350,251]	[234,153]	5	hSpCas9	negative selection	194463
203128849	203128872	1	-	26472758	KBM7	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.29495241446137677	[1276,1014]	[488,388]	-3	hSpCas9	negative selection	194464
203128942	203128965	1	+	26472758	KBM7	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	0.9189768486419814	[139,88]	[109,90]	8	hSpCas9	negative selection	194465
203128969	203128992	1	-	26472758	KBM7	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.16126627169506896	[618,636]	[458,218]	1	hSpCas9	negative selection	194466
203129011	203129034	1	-	26472758	KBM7	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	0.5206839550238325	[43,37]	[25,28]	5	hSpCas9	negative selection	194467
203129081	203129104	1	-	26472758	KBM7	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.1960853992594761	[580,448]	[272,276]	2	hSpCas9	negative selection	194468
203128919	203128942	1	+	26472758	KBM7	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.5140650011836315	[493,546]	[314,386]	5	hSpCas9	negative selection	194469
203128995	203129018	1	+	26472758	KBM7	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.8314242021585899	[549,408]	[347,440]	8	hSpCas9	negative selection	194470
203129032	203129055	1	-	26472758	Raji	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.43289893846871674	[481]	[150]	4	hSpCas9	negative selection	385579
203129092	203129115	1	-	26472758	Raji	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-3.165634959032817	[115]	[2]	-9	hSpCas9	negative selection	385580
203129159	203129182	1	-	26472758	Raji	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.001588871351002663	[197]	[45]	0	hSpCas9	negative selection	385581
203128849	203128872	1	-	26472758	Raji	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.6652059685233279	[491]	[71]	-5	hSpCas9	negative selection	385582
203128942	203128965	1	+	26472758	Raji	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	0.8916548443181623	[71]	[30]	7	hSpCas9	negative selection	385583
203128969	203128992	1	-	26472758	Raji	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	1.085244558104351	[196]	[96]	8	hSpCas9	negative selection	385584
203129011	203129034	1	-	26472758	Raji	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-1.7995070602349195	[14]	[0]	-8	hSpCas9	negative selection	385585
203129081	203129104	1	-	26472758	Raji	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.06473919796510569	[205]	[49]	0	hSpCas9	negative selection	385586
203128919	203128942	1	+	26472758	Raji	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.7161927780491235	[159]	[60]	6	hSpCas9	negative selection	385587
203128995	203129018	1	+	26472758	Raji	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.2628380540075786	[333]	[92]	2	hSpCas9	negative selection	385588
203129032	203129055	1	-	26472758	K562	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.846394338763811	[561]	[852]	7	hSpCas9	negative selection	576697
203129092	203129115	1	-	26472758	K562	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-1.0285997667399691	[86]	[35]	-5	hSpCas9	negative selection	576698
203129159	203129182	1	-	26472758	K562	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.1692613680977073	[196]	[186]	1	hSpCas9	negative selection	576699
203128849	203128872	1	-	26472758	K562	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-1.201767470183061	[1029]	[377]	-6	hSpCas9	negative selection	576700
203128942	203128965	1	+	26472758	K562	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	-0.9117004742508348	[77]	[34]	-5	hSpCas9	negative selection	576701
203128969	203128992	1	-	26472758	K562	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.14089495194664425	[620]	[577]	1	hSpCas9	negative selection	576702
203129011	203129034	1	-	26472758	K562	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	0.16195656747447407	[35]	[33]	1	hSpCas9	negative selection	576703
203129081	203129104	1	-	26472758	K562	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.8526886018796718	[306]	[467]	7	hSpCas9	negative selection	576704
203128919	203128942	1	+	26472758	K562	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	-0.47156184137042345	[454]	[276]	-3	hSpCas9	negative selection	576705
203128995	203129018	1	+	26472758	K562	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.24441872766644698	[381]	[381]	1	hSpCas9	negative selection	576706
203128897	203128920	1	+	26627737	DLD1	viability	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.08812556235768343	[303]	[23,138,104]	-1	hSpCas9	negative selection	768484
203128972	203128995	1	-	26627737	DLD1	viability	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	-0.3197294334120513	[215]	[74,41,45]	-3	hSpCas9	negative selection	768485
203129033	203129056	1	-	26627737	DLD1	viability	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.3240889345262101	[413]	[164,176,146]	3	hSpCas9	negative selection	768486
203129174	203129197	1	-	26627737	DLD1	viability	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.027949440264298353	[1560]	[502,460,471]	0	hSpCas9	negative selection	768487
203165417	203165440	1	+	26627737	DLD1	viability	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	1.7374642746756308	[133]	[200,155,72]	9	hSpCas9	negative selection	768488
203165785	203165808	1	-	26627737	DLD1	viability	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	-0.5163654201597747	[338]	[30,105,84]	-5	hSpCas9	negative selection	768489
203128897	203128920	1	+	26627737	GBM cells	viability after 5 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.028677629586264408	[135]	[48,93]	0	hSpCas9	negative selection	850799
203128972	203128995	1	-	26627737	GBM cells	viability after 5 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.1704597805749971	[168]	[116,86]	2	hSpCas9	negative selection	850800
203129033	203129056	1	-	26627737	GBM cells	viability after 5 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.23303137878096192	[164]	[120,86]	3	hSpCas9	negative selection	850801
203129174	203129197	1	-	26627737	GBM cells	viability after 5 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.6087597389263881	[744]	[232,290]	-7	hSpCas9	negative selection	850802
203165417	203165440	1	+	26627737	GBM cells	viability after 5 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	-0.2572053270315964	[155]	[92,46]	-4	hSpCas9	negative selection	850803
203165785	203165808	1	-	26627737	GBM cells	viability after 5 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	1.19568849254471	[80]	[113,84]	9	hSpCas9	negative selection	850804
203128897	203128920	1	+	26627737	GBM cells	viability after 13 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.30236399384852086	[135]	[82,40]	-4	hSpCas9	negative selection	933114
203128972	203128995	1	-	26627737	GBM cells	viability after 13 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	-0.020807102361113827	[168]	[96,84]	0	hSpCas9	negative selection	933115
203129033	203129056	1	-	26627737	GBM cells	viability after 13 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	-0.4039501908144628	[164]	[81,55]	-5	hSpCas9	negative selection	933116
203129174	203129197	1	-	26627737	GBM cells	viability after 13 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.5431465699208122	[744]	[331,232]	-6	hSpCas9	negative selection	933117
203165417	203165440	1	+	26627737	GBM cells	viability after 13 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.05565025858521189	[155]	[98,78]	0	hSpCas9	negative selection	933118
203165785	203165808	1	-	26627737	GBM cells	viability after 13 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.6163945834463282	[80]	[57,74]	7	hSpCas9	negative selection	933119
203128897	203128920	1	+	26627737	GBM cells	viability after 21 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.2501920083350936	[135]	[70,53]	-2	hSpCas9	negative selection	1015429
203128972	203128995	1	-	26627737	GBM cells	viability after 21 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	1.1670211475886876	[168]	[213,198]	9	hSpCas9	negative selection	1015430
203129033	203129056	1	-	26627737	GBM cells	viability after 21 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	-0.6778755010025083	[164]	[66,45]	-5	hSpCas9	negative selection	1015431
203129174	203129197	1	-	26627737	GBM cells	viability after 21 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.40153851259230366	[744]	[331,282]	-4	hSpCas9	negative selection	1015432
203165417	203165440	1	+	26627737	GBM cells	viability after 21 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	-0.56163166088234	[155]	[70,44]	-5	hSpCas9	negative selection	1015433
203165785	203165808	1	-	26627737	GBM cells	viability after 21 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	1.860205925741478	[80]	[176,143]	9	hSpCas9	negative selection	1015434
203128897	203128920	1	+	26627737	RPE1	viability after 9 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.030652980566779675	[258]	[50,115]	0	hSpCas9	negative selection	1097744
203128972	203128995	1	-	26627737	RPE1	viability after 9 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.7509045164964081	[516]	[243,308]	5	hSpCas9	negative selection	1097745
203129033	203129056	1	-	26627737	RPE1	viability after 9 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	-0.0802649766540417	[998]	[242,363]	0	hSpCas9	negative selection	1097746
203129174	203129197	1	-	26627737	RPE1	viability after 9 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.37742906838065227	[1610]	[490,866]	2	hSpCas9	negative selection	1097747
203165417	203165440	1	+	26627737	RPE1	viability after 9 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.15848412971147108	[517]	[149,220]	1	hSpCas9	negative selection	1097748
203165785	203165808	1	-	26627737	RPE1	viability after 9 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	-0.18670885817276073	[286]	[19,154]	-1	hSpCas9	negative selection	1097749
203128897	203128920	1	+	26627737	RPE1	viability after 12 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.12134108010578526	[258]	[96,28]	-1	hSpCas9	negative selection	1180059
203128972	203128995	1	-	26627737	RPE1	viability after 12 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.9719764448753985	[516]	[253,291]	6	hSpCas9	negative selection	1180060
203129033	203129056	1	-	26627737	RPE1	viability after 12 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.05795875440282022	[998]	[241,318]	0	hSpCas9	negative selection	1180061
203129174	203129197	1	-	26627737	RPE1	viability after 12 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.5037268227573095	[1610]	[534,696]	3	hSpCas9	negative selection	1180062
203165417	203165440	1	+	26627737	RPE1	viability after 12 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.18933156886046337	[517]	[164,151]	1	hSpCas9	negative selection	1180063
203165785	203165808	1	-	26627737	RPE1	viability after 12 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	1.3010600933283978	[286]	[138,243]	7	hSpCas9	negative selection	1180064
203128897	203128920	1	+	26627737	RPE1	viability after 15 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.3896875780361573	[258]	[3,105]	-2	hSpCas9	negative selection	1262374
203128972	203128995	1	-	26627737	RPE1	viability after 15 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.9777214037286177	[516]	[230,342]	6	hSpCas9	negative selection	1262375
203129033	203129056	1	-	26627737	RPE1	viability after 15 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	-0.5058525633146143	[998]	[169,226]	-3	hSpCas9	negative selection	1262376
203129174	203129197	1	-	26627737	RPE1	viability after 15 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.5826742010820214	[1610]	[682,681]	3	hSpCas9	negative selection	1262377
203165417	203165440	1	+	26627737	RPE1	viability after 15 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.24621358988909942	[517]	[156,189]	1	hSpCas9	negative selection	1262378
203165785	203165808	1	-	26627737	RPE1	viability after 15 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	1.0853821269652675	[286]	[156,186]	6	hSpCas9	negative selection	1262379
203128897	203128920	1	+	26627737	RPE1	viability after 18 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	0.38253180214685045	[258]	[79,102]	2	hSpCas9	negative selection	1344689
203128972	203128995	1	-	26627737	RPE1	viability after 18 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.7039121408032205	[516]	[205,249]	4	hSpCas9	negative selection	1344690
203129033	203129056	1	-	26627737	RPE1	viability after 18 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	-0.4545657299653833	[998]	[188,204]	-3	hSpCas9	negative selection	1344691
203129174	203129197	1	-	26627737	RPE1	viability after 18 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.22773139372988482	[1610]	[511,505]	1	hSpCas9	negative selection	1344692
203165417	203165440	1	+	26627737	RPE1	viability after 18 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.06642620502711816	[517]	[171,118]	0	hSpCas9	negative selection	1344693
203165785	203165808	1	-	26627737	RPE1	viability after 18 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.9656091720610174	[286]	[114,189]	6	hSpCas9	negative selection	1344694
203128897	203128920	1	+	26627737	HeLa	viability after 8 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.9754671462474259	[390]	[132,141,0]	-7	hSpCas9	negative selection	1427004
203128972	203128995	1	-	26627737	HeLa	viability after 8 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	1.0533602601326695	[146]	[237,88,96]	7	hSpCas9	negative selection	1427005
203129033	203129056	1	-	26627737	HeLa	viability after 8 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	1.0248926531745415	[229]	[245,151,220]	7	hSpCas9	negative selection	1427006
203129174	203129197	1	-	26627737	HeLa	viability after 8 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.601410032128068	[620]	[463,340,434]	5	hSpCas9	negative selection	1427007
203165417	203165440	1	+	26627737	HeLa	viability after 8 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.765970657460993	[146]	[237,55,63]	6	hSpCas9	negative selection	1427008
203165785	203165808	1	-	26627737	HeLa	viability after 8 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	-0.5301353673594996	[219]	[128,36,47]	-5	hSpCas9	negative selection	1427009
203128897	203128920	1	+	26627737	HeLa	viability after 12 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-1.5386968467449018	[390]	[49,80,32]	-8	hSpCas9	negative selection	1509319
203128972	203128995	1	-	26627737	HeLa	viability after 12 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	1.0178494033646333	[146]	[94,143,126]	7	hSpCas9	negative selection	1509320
203129033	203129056	1	-	26627737	HeLa	viability after 12 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.2546407352563028	[229]	[159,61,124]	2	hSpCas9	negative selection	1509321
203129174	203129197	1	-	26627737	HeLa	viability after 12 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.9661468765705707	[620]	[436,531,529]	7	hSpCas9	negative selection	1509322
203165417	203165440	1	+	26627737	HeLa	viability after 12 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	1.152150746198523	[146]	[143,118,143]	8	hSpCas9	negative selection	1509323
203165785	203165808	1	-	26627737	HeLa	viability after 12 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.5641216904146615	[219]	[92,134,173]	5	hSpCas9	negative selection	1509324
203128897	203128920	1	+	26627737	HeLa	viability after 15 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.22977893148569004	[390]	[211,0,197]	-2	hSpCas9	negative selection	1591634
203128972	203128995	1	-	26627737	HeLa	viability after 15 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	1.0052399036685178	[146]	[144,167,40]	7	hSpCas9	negative selection	1591635
203129033	203129056	1	-	26627737	HeLa	viability after 15 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.3787136260018208	[229]	[47,113,210]	3	hSpCas9	negative selection	1591636
203129174	203129197	1	-	26627737	HeLa	viability after 15 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.5030002932305568	[620]	[478,214,380]	4	hSpCas9	negative selection	1591637
203165417	203165440	1	+	26627737	HeLa	viability after 15 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.33764362438449513	[146]	[16,45,171]	3	hSpCas9	negative selection	1591638
203165785	203165808	1	-	26627737	HeLa	viability after 15 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	-0.6870777165394318	[219]	[42,68,54]	-6	hSpCas9	negative selection	1591639
203128897	203128920	1	+	26627737	HeLa	viability after 18 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.24134093951931876	[390]	[139,0,197]	-2	hSpCas9	negative selection	1673949
203128972	203128995	1	-	26627737	HeLa	viability after 18 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	1.0527512091091178	[146]	[109,132,40]	7	hSpCas9	negative selection	1673950
203129033	203129056	1	-	26627737	HeLa	viability after 18 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.35956452923397736	[229]	[30,91,210]	3	hSpCas9	negative selection	1673951
203129174	203129197	1	-	26627737	HeLa	viability after 18 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.5409725160979104	[620]	[335,182,380]	4	hSpCas9	negative selection	1673952
203165417	203165440	1	+	26627737	HeLa	viability after 18 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.3131357350561548	[146]	[8,37,171]	2	hSpCas9	negative selection	1673953
203165785	203165808	1	-	26627737	HeLa	viability after 18 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	-0.7380820557431401	[219]	[25,55,54]	-6	hSpCas9	negative selection	1673954
203128897	203128920	1	+	26627737	HCT116	viability after 6 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.509351573154762	[269]	[43,21]	-3	hSpCas9	negative selection	1756264
203128972	203128995	1	-	26627737	HCT116	viability after 6 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.5479529857237323	[245]	[149,4]	3	hSpCas9	negative selection	1756265
203129033	203129056	1	-	26627737	HCT116	viability after 6 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.5485917879216653	[200]	[71,31]	3	hSpCas9	negative selection	1756266
203129174	203129197	1	-	26627737	HCT116	viability after 6 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.015372505771638068	[2786]	[408,446]	0	hSpCas9	negative selection	1756267
203165417	203165440	1	+	26627737	HCT116	viability after 6 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.886276873262813	[453]	[51,175]	5	hSpCas9	negative selection	1756268
203165785	203165808	1	-	26627737	HCT116	viability after 6 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	1.4265230550105379	[190]	[81,79]	7	hSpCas9	negative selection	1756269
203128897	203128920	1	+	26627737	HCT116	viability after 8 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	2.37310645461447	[32]	[80,158,42]	9	hSpCas9	negative selection	1838579
203128972	203128995	1	-	26627737	HCT116	viability after 8 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	-0.1544568580954261	[222]	[173,101,56]	-2	hSpCas9	negative selection	1838580
203129033	203129056	1	-	26627737	HCT116	viability after 8 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.9127453002757048	[129]	[247,56,101]	8	hSpCas9	negative selection	1838581
203129174	203129197	1	-	26627737	HCT116	viability after 8 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.468925746103547	[1201]	[358,473,598]	-5	hSpCas9	negative selection	1838582
203165417	203165440	1	+	26627737	HCT116	viability after 8 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	2.6007692421764865	[34]	[119,111,118]	9	hSpCas9	negative selection	1838583
203165785	203165808	1	-	26627737	HCT116	viability after 8 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.2138922186872308	[204]	[111,91,187]	2	hSpCas9	negative selection	1838584
203128897	203128920	1	+	26627737	HCT116	viability after 9 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	0.5789641753781373	[269]	[143,78]	4	hSpCas9	negative selection	1920894
203128972	203128995	1	-	26627737	HCT116	viability after 9 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	1.5356106998802426	[245]	[109,253]	8	hSpCas9	negative selection	1920895
203129033	203129056	1	-	26627737	HCT116	viability after 9 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	1.4385007805121677	[200]	[202,99]	8	hSpCas9	negative selection	1920896
203129174	203129197	1	-	26627737	HCT116	viability after 9 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.9420420677275416	[2786]	[550,257]	-6	hSpCas9	negative selection	1920897
203165417	203165440	1	+	26627737	HCT116	viability after 9 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	-1.7614146952877194	[453]	[18,48]	-8	hSpCas9	negative selection	1920898
203165785	203165808	1	-	26627737	HCT116	viability after 9 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	1.261065571530813	[190]	[57,172]	8	hSpCas9	negative selection	1920899
203128897	203128920	1	+	26627737	HCT116	viability after 12 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	2.0553216144108157	[32]	[140,22,44]	9	hSpCas9	negative selection	2003209
203128972	203128995	1	-	26627737	HCT116	viability after 12 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.16999496279014226	[222]	[121,114,158]	1	hSpCas9	negative selection	2003210
203129033	203129056	1	-	26627737	HCT116	viability after 12 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	1.1875271599226445	[129]	[225,170,63]	8	hSpCas9	negative selection	2003211
203129174	203129197	1	-	26627737	HCT116	viability after 12 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.25096720016223717	[1201]	[550,501,536]	-3	hSpCas9	negative selection	2003212
203165417	203165440	1	+	26627737	HCT116	viability after 12 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	2.452341493809159	[34]	[84,84,132]	9	hSpCas9	negative selection	2003213
203165785	203165808	1	-	26627737	HCT116	viability after 12 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	-0.19063931271652146	[204]	[34,159,94]	-2	hSpCas9	negative selection	2003214
203128897	203128920	1	+	26627737	HCT116	viability after 15 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	1.8957473758103491	[32]	[105,48,60]	9	hSpCas9	negative selection	2085524
203128972	203128995	1	-	26627737	HCT116	viability after 15 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	-0.13125217846109039	[222]	[144,74,133]	-1	hSpCas9	negative selection	2085525
203129033	203129056	1	-	26627737	HCT116	viability after 15 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.5985939323269883	[129]	[159,165,19]	5	hSpCas9	negative selection	2085526
203129174	203129197	1	-	26627737	HCT116	viability after 15 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.38983371955240975	[1201]	[556,481,544]	-4	hSpCas9	negative selection	2085527
203165417	203165440	1	+	26627737	HCT116	viability after 15 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	2.812412365334831	[34]	[165,151,108]	9	hSpCas9	negative selection	2085528
203165785	203165808	1	-	26627737	HCT116	viability after 15 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	-0.031615436262868224	[204]	[176,55,119]	0	hSpCas9	negative selection	2085529
203128897	203128920	1	+	26627737	HCT116	viability after 18 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	1.6390085523765971	[32]	[65,34,48]	9	hSpCas9	negative selection	2167839
203128972	203128995	1	-	26627737	HCT116	viability after 18 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.14926756996253626	[222]	[135,92,131]	1	hSpCas9	negative selection	2167840
203129033	203129056	1	-	26627737	HCT116	viability after 18 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.972770688027791	[129]	[169,95,104]	7	hSpCas9	negative selection	2167841
203129174	203129197	1	-	26627737	HCT116	viability after 18 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.06445120100046053	[1201]	[506,559,601]	0	hSpCas9	negative selection	2167842
203165417	203165440	1	+	26627737	HCT116	viability after 18 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	3.1879328660250352	[34]	[130,185,142]	9	hSpCas9	negative selection	2167843
203165785	203165808	1	-	26627737	HCT116	viability after 18 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	-0.5401161444374954	[204]	[38,126,32]	-5	hSpCas9	negative selection	2167844
203160765	203160788	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCACTGCACTCCAGCCTAG	ADORA1	ENSG00000163485	-0.41902599900673143	[34,218]	[4,37]	-2	dCas9-VP64	positive selection	2439512
203160583	203160606	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGGATCACTTGAGCCCTGG	ADORA1	ENSG00000163485	1.3448043646809227	[134,24]	[56,28]	5	dCas9-VP64	positive selection	2469846
203160765	203160788	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCACTGCACTCCAGCCTAG	ADORA1	ENSG00000163485	0.0771162345407751	[282,156]	[110,43]	0	dCas9-VP64	positive selection	2534767
203160583	203160606	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGGATCACTTGAGCCCTGG	ADORA1	ENSG00000163485	0.9689409693551694	[107,845]	[92,495]	6	dCas9-VP64	positive selection	2565101
203128865	203128888	1	-	27260157	DLD1	viability	CGATGCCGATGTAGGCGGCCTGG	ADORA1	ENSG00000163485	0.31988251001293	[]	[]	4	hSpCas9	negative selection	2575383
203165286	203165309	1	+	27260157	DLD1	viability	AGGGCGGCGGTGGCCATAGCCGG	ADORA1	ENSG00000163485	0.00626070184073905	[]	[]	0	hSpCas9	negative selection	2579046
203165412	203165435	1	-	27260157	DLD1	viability	TCGAACTCGCACTTGATCACGGG	ADORA1	ENSG00000163485	-0.689688762262825	[]	[]	-5	hSpCas9	negative selection	2587674
203129174	203129197	1	-	27260157	DLD1	viability	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.893301143354644	[]	[]	9	hSpCas9	negative selection	2608332
203165281	203165304	1	-	27260157	DLD1	viability	TATGGCCACCGCCGCCCTCCGGG	ADORA1	ENSG00000163485	0.00187319904494527	[]	[]	0	hSpCas9	negative selection	2608955
203165606	203165629	1	+	27260157	DLD1	viability	GCTGAAGATCGCCAAGTCGCTGG	ADORA1	ENSG00000163485	-0.11625999004054	[]	[]	-1	hSpCas9	negative selection	2609422
203128952	203128975	1	-	27260157	DLD1	viability	AGGTGGCATCCCGCAGCGCCTGG	ADORA1	ENSG00000163485	0.265875839823424	[]	[]	4	hSpCas9	negative selection	2609469
203165417	203165440	1	+	27260157	DLD1	viability	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	-0.214044770561876	[]	[]	-2	hSpCas9	negative selection	2610274
203129143	203129166	1	+	27260157	DLD1	viability	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	1.47275708815657	[]	[]	9	hSpCas9	negative selection	2611181
203128883	203128906	1	+	27260157	DLD1	viability	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	0.955900093291324	[]	[]	9	hSpCas9	negative selection	2611285
203165299	203165322	1	-	27260157	DLD1	viability	GAGGATCCAGCAGCCGGCTATGG	ADORA1	ENSG00000163485	0.679057208447696	[]	[]	8	hSpCas9	negative selection	2614148
203165534	203165557	1	-	27260157	DLD1	viability	TGTTGAGCTGCTTGCGGATTAGG	ADORA1	ENSG00000163485	-0.345227450557434	[]	[]	-3	hSpCas9	negative selection	2614884
203165577	203165600	1	+	27260157	DLD1	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.216117843991798	[]	[]	-2	hSpCas9	negative selection	2616125
203165715	203165738	1	-	27260157	DLD1	viability	GCAATGTAGGTAAGGATGCTGGG	ADORA1	ENSG00000163485	0.103100410428261	[]	[]	3	hSpCas9	negative selection	2616386
203128896	203128919	1	+	27260157	DLD1	viability	ATCGCCCTGGTCTCTGTGCCCGG	ADORA1	ENSG00000163485	-0.0214541117062819	[]	[]	0	hSpCas9	negative selection	2619004
203129153	203129176	1	-	27260157	DLD1	viability	GGATCTTGACCCGGAGGTAGCGG	ADORA1	ENSG00000163485	0.910333347877823	[]	[]	9	hSpCas9	negative selection	2619103
203165569	203165592	1	-	27260157	DLD1	viability	CTTCTGCGGGTCGCCGGAGGAGG	ADORA1	ENSG00000163485	-0.0998521413283766	[]	[]	0	hSpCas9	negative selection	2621105
203165309	203165332	1	+	27260157	DLD1	viability	CTGCTGGATCCTCTCCTTCGTGG	ADORA1	ENSG00000163485	0.540203717140576	[]	[]	8	hSpCas9	negative selection	2642551
203165386	203165409	1	+	27260157	DLD1	viability	GGGCAGCCAACGGCAGCATGGGG	ADORA1	ENSG00000163485	-0.586460980765294	[]	[]	-5	hSpCas9	negative selection	2643897
203128988	203129011	1	+	27260157	DLD1	viability	GTCGCTGGCGGTGGCTGATGTGG	ADORA1	ENSG00000163485	-0.171042231125999	[]	[]	-1	hSpCas9	negative selection	2644860
203128865	203128888	1	-	27260157	HT1080	viability	CGATGCCGATGTAGGCGGCCTGG	ADORA1	ENSG00000163485	-0.887881009452286	[]	[]	-8	hSpCas9	negative selection	2651513
203165286	203165309	1	+	27260157	HT1080	viability	AGGGCGGCGGTGGCCATAGCCGG	ADORA1	ENSG00000163485	0.166800884481623	[]	[]	1	hSpCas9	negative selection	2655176
203165412	203165435	1	-	27260157	HT1080	viability	TCGAACTCGCACTTGATCACGGG	ADORA1	ENSG00000163485	0.239985141983643	[]	[]	2	hSpCas9	negative selection	2663804
203129174	203129197	1	-	27260157	HT1080	viability	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.362243576910409	[]	[]	3	hSpCas9	negative selection	2684462
203165281	203165304	1	-	27260157	HT1080	viability	TATGGCCACCGCCGCCCTCCGGG	ADORA1	ENSG00000163485	-0.00561129081052327	[]	[]	0	hSpCas9	negative selection	2685085
203165606	203165629	1	+	27260157	HT1080	viability	GCTGAAGATCGCCAAGTCGCTGG	ADORA1	ENSG00000163485	1.51686507697491	[]	[]	9	hSpCas9	negative selection	2685552
203128952	203128975	1	-	27260157	HT1080	viability	AGGTGGCATCCCGCAGCGCCTGG	ADORA1	ENSG00000163485	0.461696049590894	[]	[]	4	hSpCas9	negative selection	2685599
203165417	203165440	1	+	27260157	HT1080	viability	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	1.15980476451296	[]	[]	8	hSpCas9	negative selection	2686404
203129143	203129166	1	+	27260157	HT1080	viability	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	-0.359442676171504	[]	[]	-7	hSpCas9	negative selection	2687311
203128883	203128906	1	+	27260157	HT1080	viability	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	0.781211374160607	[]	[]	6	hSpCas9	negative selection	2687415
203165299	203165322	1	-	27260157	HT1080	viability	GAGGATCCAGCAGCCGGCTATGG	ADORA1	ENSG00000163485	0.702713585065065	[]	[]	6	hSpCas9	negative selection	2690278
203165534	203165557	1	-	27260157	HT1080	viability	TGTTGAGCTGCTTGCGGATTAGG	ADORA1	ENSG00000163485	0.134211829309626	[]	[]	1	hSpCas9	negative selection	2691014
203165577	203165600	1	+	27260157	HT1080	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.472683225397565	[]	[]	4	hSpCas9	negative selection	2692255
203165715	203165738	1	-	27260157	HT1080	viability	GCAATGTAGGTAAGGATGCTGGG	ADORA1	ENSG00000163485	0.857449140048353	[]	[]	7	hSpCas9	negative selection	2692516
203128896	203128919	1	+	27260157	HT1080	viability	ATCGCCCTGGTCTCTGTGCCCGG	ADORA1	ENSG00000163485	0.266429150280307	[]	[]	2	hSpCas9	negative selection	2695134
203129153	203129176	1	-	27260157	HT1080	viability	GGATCTTGACCCGGAGGTAGCGG	ADORA1	ENSG00000163485	0.106915843996484	[]	[]	1	hSpCas9	negative selection	2695233
203165569	203165592	1	-	27260157	HT1080	viability	CTTCTGCGGGTCGCCGGAGGAGG	ADORA1	ENSG00000163485	-0.635055289587715	[]	[]	-8	hSpCas9	negative selection	2697235
203165309	203165332	1	+	27260157	HT1080	viability	CTGCTGGATCCTCTCCTTCGTGG	ADORA1	ENSG00000163485	0.0126777019865769	[]	[]	0	hSpCas9	negative selection	2718681
203165386	203165409	1	+	27260157	HT1080	viability	GGGCAGCCAACGGCAGCATGGGG	ADORA1	ENSG00000163485	0.235119558740008	[]	[]	2	hSpCas9	negative selection	2720027
203128988	203129011	1	+	27260157	HT1080	viability	GTCGCTGGCGGTGGCTGATGTGG	ADORA1	ENSG00000163485	-0.620339740993112	[]	[]	-8	hSpCas9	negative selection	2720990
203128865	203128888	1	-	27260157	MKN45	viability	CGATGCCGATGTAGGCGGCCTGG	ADORA1	ENSG00000163485	0.557707746415682	[]	[]	7	hSpCas9	negative selection	2727643
203165286	203165309	1	+	27260157	MKN45	viability	AGGGCGGCGGTGGCCATAGCCGG	ADORA1	ENSG00000163485	-0.328856517172134	[]	[]	-1	hSpCas9	negative selection	2731306
203165412	203165435	1	-	27260157	MKN45	viability	TCGAACTCGCACTTGATCACGGG	ADORA1	ENSG00000163485	-2.15349461658804	[]	[]	-9	hSpCas9	negative selection	2739934
203129174	203129197	1	-	27260157	MKN45	viability	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.342333506073667	[]	[]	6	hSpCas9	negative selection	2760592
203165281	203165304	1	-	27260157	MKN45	viability	TATGGCCACCGCCGCCCTCCGGG	ADORA1	ENSG00000163485	0.142880643050519	[]	[]	5	hSpCas9	negative selection	2761215
203165606	203165629	1	+	27260157	MKN45	viability	GCTGAAGATCGCCAAGTCGCTGG	ADORA1	ENSG00000163485	2.08573270999054	[]	[]	9	hSpCas9	negative selection	2761682
203128952	203128975	1	-	27260157	MKN45	viability	AGGTGGCATCCCGCAGCGCCTGG	ADORA1	ENSG00000163485	0.438252554603371	[]	[]	6	hSpCas9	negative selection	2761729
203165417	203165440	1	+	27260157	MKN45	viability	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.880790478606445	[]	[]	8	hSpCas9	negative selection	2762534
203129143	203129166	1	+	27260157	MKN45	viability	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	0.449264254533274	[]	[]	6	hSpCas9	negative selection	2763441
203128883	203128906	1	+	27260157	MKN45	viability	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	0.918534671160438	[]	[]	8	hSpCas9	negative selection	2763545
203165299	203165322	1	-	27260157	MKN45	viability	GAGGATCCAGCAGCCGGCTATGG	ADORA1	ENSG00000163485	0.96591440864433	[]	[]	8	hSpCas9	negative selection	2766408
203165534	203165557	1	-	27260157	MKN45	viability	TGTTGAGCTGCTTGCGGATTAGG	ADORA1	ENSG00000163485	0.378083774069378	[]	[]	6	hSpCas9	negative selection	2767144
203165577	203165600	1	+	27260157	MKN45	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.848316643080306	[]	[]	8	hSpCas9	negative selection	2768385
203165715	203165738	1	-	27260157	MKN45	viability	GCAATGTAGGTAAGGATGCTGGG	ADORA1	ENSG00000163485	0.47702793238238	[]	[]	6	hSpCas9	negative selection	2768646
203128896	203128919	1	+	27260157	MKN45	viability	ATCGCCCTGGTCTCTGTGCCCGG	ADORA1	ENSG00000163485	0.942826452158743	[]	[]	8	hSpCas9	negative selection	2771264
203129153	203129176	1	-	27260157	MKN45	viability	GGATCTTGACCCGGAGGTAGCGG	ADORA1	ENSG00000163485	-0.00925900651267769	[]	[]	0	hSpCas9	negative selection	2771363
203165569	203165592	1	-	27260157	MKN45	viability	CTTCTGCGGGTCGCCGGAGGAGG	ADORA1	ENSG00000163485	-1.32007800239516	[]	[]	-8	hSpCas9	negative selection	2773365
203165309	203165332	1	+	27260157	MKN45	viability	CTGCTGGATCCTCTCCTTCGTGG	ADORA1	ENSG00000163485	0.994924539148915	[]	[]	8	hSpCas9	negative selection	2794811
203165386	203165409	1	+	27260157	MKN45	viability	GGGCAGCCAACGGCAGCATGGGG	ADORA1	ENSG00000163485	-0.641637705702935	[]	[]	-7	hSpCas9	negative selection	2796157
203128988	203129011	1	+	27260157	MKN45	viability	GTCGCTGGCGGTGGCTGATGTGG	ADORA1	ENSG00000163485	0.151541012239937	[]	[]	5	hSpCas9	negative selection	2797120
203128865	203128888	1	-	27260157	RKO	viability	CGATGCCGATGTAGGCGGCCTGG	ADORA1	ENSG00000163485	0.399735038133891	[]	[]	2	hSpCas9	negative selection	2803773
203165286	203165309	1	+	27260157	RKO	viability	AGGGCGGCGGTGGCCATAGCCGG	ADORA1	ENSG00000163485	-0.0633799687421909	[]	[]	0	hSpCas9	negative selection	2807436
203165412	203165435	1	-	27260157	RKO	viability	TCGAACTCGCACTTGATCACGGG	ADORA1	ENSG00000163485	-0.112878781767201	[]	[]	0	hSpCas9	negative selection	2816064
203129174	203129197	1	-	27260157	RKO	viability	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.96438471126471	[]	[]	8	hSpCas9	negative selection	2836722
203165281	203165304	1	-	27260157	RKO	viability	TATGGCCACCGCCGCCCTCCGGG	ADORA1	ENSG00000163485	0.22198544042493	[]	[]	1	hSpCas9	negative selection	2837345
203165606	203165629	1	+	27260157	RKO	viability	GCTGAAGATCGCCAAGTCGCTGG	ADORA1	ENSG00000163485	1.1583288402844	[]	[]	9	hSpCas9	negative selection	2837812
203128952	203128975	1	-	27260157	RKO	viability	AGGTGGCATCCCGCAGCGCCTGG	ADORA1	ENSG00000163485	0.593425616009085	[]	[]	3	hSpCas9	negative selection	2837859
203165417	203165440	1	+	27260157	RKO	viability	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.944138813677873	[]	[]	8	hSpCas9	negative selection	2838664
203129143	203129166	1	+	27260157	RKO	viability	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	0.678351419674011	[]	[]	7	hSpCas9	negative selection	2839571
203128883	203128906	1	+	27260157	RKO	viability	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	0.930652800948107	[]	[]	8	hSpCas9	negative selection	2839675
203165299	203165322	1	-	27260157	RKO	viability	GAGGATCCAGCAGCCGGCTATGG	ADORA1	ENSG00000163485	0.653169597081193	[]	[]	3	hSpCas9	negative selection	2842538
203165534	203165557	1	-	27260157	RKO	viability	TGTTGAGCTGCTTGCGGATTAGG	ADORA1	ENSG00000163485	-0.306143655396897	[]	[]	-6	hSpCas9	negative selection	2843274
203165577	203165600	1	+	27260157	RKO	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.162437210080376	[]	[]	0	hSpCas9	negative selection	2844515
203165715	203165738	1	-	27260157	RKO	viability	GCAATGTAGGTAAGGATGCTGGG	ADORA1	ENSG00000163485	0.100627480706641	[]	[]	0	hSpCas9	negative selection	2844776
203128896	203128919	1	+	27260157	RKO	viability	ATCGCCCTGGTCTCTGTGCCCGG	ADORA1	ENSG00000163485	0.649656931269002	[]	[]	3	hSpCas9	negative selection	2847394
203129153	203129176	1	-	27260157	RKO	viability	GGATCTTGACCCGGAGGTAGCGG	ADORA1	ENSG00000163485	-1.16660545879788	[]	[]	-8	hSpCas9	negative selection	2847493
203165569	203165592	1	-	27260157	RKO	viability	CTTCTGCGGGTCGCCGGAGGAGG	ADORA1	ENSG00000163485	-0.603776699228672	[]	[]	-7	hSpCas9	negative selection	2849495
203165309	203165332	1	+	27260157	RKO	viability	CTGCTGGATCCTCTCCTTCGTGG	ADORA1	ENSG00000163485	1.25899514295152	[]	[]	9	hSpCas9	negative selection	2870941
203165386	203165409	1	+	27260157	RKO	viability	GGGCAGCCAACGGCAGCATGGGG	ADORA1	ENSG00000163485	0.340257785764722	[]	[]	1	hSpCas9	negative selection	2872287
203128988	203129011	1	+	27260157	RKO	viability	GTCGCTGGCGGTGGCTGATGTGG	ADORA1	ENSG00000163485	-0.363295476434274	[]	[]	-6	hSpCas9	negative selection	2873250
203128865	203128888	1	-	27260157	SF268	viability	CGATGCCGATGTAGGCGGCCTGG	ADORA1	ENSG00000163485	-0.138632760630485	[]	[]	-1	hSpCas9	negative selection	2879903
203165286	203165309	1	+	27260157	SF268	viability	AGGGCGGCGGTGGCCATAGCCGG	ADORA1	ENSG00000163485	-0.537897793826033	[]	[]	-4	hSpCas9	negative selection	2883566
203165412	203165435	1	-	27260157	SF268	viability	TCGAACTCGCACTTGATCACGGG	ADORA1	ENSG00000163485	0.0486145304162265	[]	[]	0	hSpCas9	negative selection	2892194
203129174	203129197	1	-	27260157	SF268	viability	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.259326825785314	[]	[]	4	hSpCas9	negative selection	2912852
203165281	203165304	1	-	27260157	SF268	viability	TATGGCCACCGCCGCCCTCCGGG	ADORA1	ENSG00000163485	-0.0927205171644481	[]	[]	0	hSpCas9	negative selection	2913475
203165606	203165629	1	+	27260157	SF268	viability	GCTGAAGATCGCCAAGTCGCTGG	ADORA1	ENSG00000163485	0.553954762378329	[]	[]	8	hSpCas9	negative selection	2913942
203128952	203128975	1	-	27260157	SF268	viability	AGGTGGCATCCCGCAGCGCCTGG	ADORA1	ENSG00000163485	0.187111093343559	[]	[]	0	hSpCas9	negative selection	2913989
203165417	203165440	1	+	27260157	SF268	viability	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.0686165150939578	[]	[]	0	hSpCas9	negative selection	2914794
203129143	203129166	1	+	27260157	SF268	viability	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	0.960302247660524	[]	[]	9	hSpCas9	negative selection	2915701
203128883	203128906	1	+	27260157	SF268	viability	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	0.95590389858707	[]	[]	9	hSpCas9	negative selection	2915805
203165299	203165322	1	-	27260157	SF268	viability	GAGGATCCAGCAGCCGGCTATGG	ADORA1	ENSG00000163485	1.4704624274413	[]	[]	9	hSpCas9	negative selection	2918668
203165534	203165557	1	-	27260157	SF268	viability	TGTTGAGCTGCTTGCGGATTAGG	ADORA1	ENSG00000163485	0.5786788915493	[]	[]	8	hSpCas9	negative selection	2919404
203165577	203165600	1	+	27260157	SF268	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.739710341337384	[]	[]	8	hSpCas9	negative selection	2920645
203165715	203165738	1	-	27260157	SF268	viability	GCAATGTAGGTAAGGATGCTGGG	ADORA1	ENSG00000163485	0.905962047063618	[]	[]	9	hSpCas9	negative selection	2920906
203128896	203128919	1	+	27260157	SF268	viability	ATCGCCCTGGTCTCTGTGCCCGG	ADORA1	ENSG00000163485	1.40691474692848	[]	[]	9	hSpCas9	negative selection	2923524
203129153	203129176	1	-	27260157	SF268	viability	GGATCTTGACCCGGAGGTAGCGG	ADORA1	ENSG00000163485	-0.285980830588794	[]	[]	-2	hSpCas9	negative selection	2923623
203165569	203165592	1	-	27260157	SF268	viability	CTTCTGCGGGTCGCCGGAGGAGG	ADORA1	ENSG00000163485	-0.456848046434166	[]	[]	-4	hSpCas9	negative selection	2925625
203165309	203165332	1	+	27260157	SF268	viability	CTGCTGGATCCTCTCCTTCGTGG	ADORA1	ENSG00000163485	0.662643034159055	[]	[]	8	hSpCas9	negative selection	2947071
203165386	203165409	1	+	27260157	SF268	viability	GGGCAGCCAACGGCAGCATGGGG	ADORA1	ENSG00000163485	0.0236460164377656	[]	[]	0	hSpCas9	negative selection	2948417
203128988	203129011	1	+	27260157	SF268	viability	GTCGCTGGCGGTGGCTGATGTGG	ADORA1	ENSG00000163485	-0.158398925820063	[]	[]	-1	hSpCas9	negative selection	2949380
203129032	203129055	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	-0.10418181367825861	[3,3]	[3,2]	-1	hSpCas9	positive selection	2969167
203165268	203165291	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGGTGGTGACCCCCCGGAGGG	ADORA1	ENSG00000163485	0.20374585325183656	[3,3]	[3,2]	4	hSpCas9	positive selection	2969168
203129159	203129182	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.2661418934900097	[3,2]	[3,2]	5	hSpCas9	positive selection	2969169
203128845	203128868	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGAAAGCTGAGATGGAGGGCGG	ADORA1	ENSG00000163485	0.05200379814318773	[5,5]	[4,4]	1	hSpCas9	positive selection	2969170
203129032	203129055	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.19075573160172762	[3,3]	[2,3]	3	hSpCas9	positive selection	3037025
203165268	203165291	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGGTGGTGACCCCCCGGAGGG	ADORA1	ENSG00000163485	0.06487281726391793	[3,3]	[2,1]	1	hSpCas9	positive selection	3037026
203129159	203129182	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	-0.3684384629164212	[3,3]	[2,0]	-5	hSpCas9	positive selection	3037027
203128845	203128868	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGAAAGCTGAGATGGAGGGCGG	ADORA1	ENSG00000163485	0.1856327614054778	[5,5]	[4,3]	3	hSpCas9	positive selection	3037028
203128883	203128906		+	24336571	A375	resistance to PLX after 7 days	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	0.2680233831569507	[12,11]	[14,14]	7	hSpCas9	positive selection	3106726
203129081	203129104		-	24336571	A375	resistance to PLX after 7 days	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.2565853150843679	[6,9]	[6,6]	-7	hSpCas9	positive selection	3106737
203165577	203165600		+	24336571	A375	resistance to PLX after 7 days	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.21557166114841286	[2,2]	[2,3]	6	hSpCas9	positive selection	3106748
203129143	203129166		+	24336571	A375	resistance to PLX after 7 days	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	-0.09678631728786968	[24,21]	[20,22]	-3	hSpCas9	positive selection	3106759
203128883	203128906		+	24336571	A375	resistance to PLX after 14 days	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	-0.1619025315440723	[9,18]	[4,6]	-2	hSpCas9	positive selection	3164519
203129081	203129104		-	24336571	A375	resistance to PLX after 14 days	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.8395120691676716	[7,11]	[1,1]	-8	hSpCas9	positive selection	3164530
203165577	203165600		+	24336571	A375	resistance to PLX after 14 days	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.569211628916855	[2,1]	[1,1]	5	hSpCas9	positive selection	3164541
203129143	203129166		+	24336571	A375	resistance to PLX after 14 days	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	-0.011449454530806147	[32,18]	[11,11]	0	hSpCas9	positive selection	3164552
203128883	203128906		+	24336571	A375	viability after 7 days	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	-0.92831956549614	[25]	[12,11]	-8	hSpCas9	negative selection	3222312
203129081	203129104		-	24336571	A375	viability after 7 days	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.5294428919931125	[5]	[6,9]	7	hSpCas9	negative selection	3222323
203165577	203165600		+	24336571	A375	viability after 7 days	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.6202524419267461	[4]	[2,2]	-7	hSpCas9	negative selection	3222334
203129143	203129166		+	24336571	A375	viability after 7 days	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	0.166486044634798	[21]	[24,21]	2	hSpCas9	negative selection	3222345
203128883	203128906		+	24336571	A375	viability after 14 days	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	-0.7326398069889104	[25]	[9,18]	-7	hSpCas9	negative selection	3280105
203129081	203129104		-	24336571	A375	viability after 14 days	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.7851565153069207	[5]	[7,11]	8	hSpCas9	negative selection	3280116
203165577	203165600		+	24336571	A375	viability after 14 days	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.7000129690071168	[4]	[2,1]	-7	hSpCas9	negative selection	3280127
203129143	203129166		+	24336571	A375	viability after 14 days	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	0.33001251756462024	[21]	[32,18]	4	hSpCas9	negative selection	3280138
203165577	203165600	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	1.096202563750843	[80,61]	[0,0]	5	hSpCas9	positive selection	3335755
203165413	203165436	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.5302955953373486	[143,173]	[0,1]	2	hSpCas9	positive selection	3335756
203128973	203128996	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	-1.5810744147122207	[494,419]	[0,0]	-9	hSpCas9	positive selection	3335757
203129081	203129104	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	5.210020496667479	[619,619]	[149,149]	9	hSpCas9	positive selection	3355004
203165889	203165912	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	2.556886493304743	[25,25]	[0,0]	8	hSpCas9	positive selection	3355005
203165744	203165767	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.7256673632484749	[252,252]	[0,0]	-5	hSpCas9	positive selection	3355006
203129032	203129055	1	-	26780180	HT29	viability (Avana library 4 designs)	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	1.98542947603303	[]	[]	7	hSpCas9	negative selection	3405231
203165267	203165290	1	+	26780180	HT29	viability (Avana library 4 designs)	GATGGTGGTGACCCCCCGGAGGG	ADORA1	ENSG00000163485	1.903263152738	[]	[]	7	hSpCas9	negative selection	3405232
203129159	203129182	1	-	26780180	HT29	viability (Avana library 4 designs)	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	2.63128979319994	[]	[]	8	hSpCas9	negative selection	3405233
203128845	203128868	1	-	26780180	HT29	viability (Avana library 4 designs)	TGGAAAGCTGAGATGGAGGGCGG	ADORA1	ENSG00000163485	0.405467894372986	[]	[]	1	hSpCas9	negative selection	3405234
203165267	203165290	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGTGGTGACCCCCCGGAGGG	ADORA1	ENSG00000163485	2.75851224152088	[]	[]	4	hSpCas9	negative selection	3477143
203128845	203128868	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGAAAGCTGAGATGGAGGGCGG	ADORA1	ENSG00000163485	5.10454776305583	[]	[]	8	hSpCas9	negative selection	3477144
203129159	203129182	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	4.31721674988577	[]	[]	7	hSpCas9	negative selection	3477145
203129032	203129055	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.0202689424170894	[]	[]	0	hSpCas9	negative selection	3477146
203128919	203128942	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	2.12441282012405	[]	[]	3	hSpCas9	negative selection	3477147
203129081	203129104	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	6.58609556038232	[]	[]	9	hSpCas9	negative selection	3477148
203165267	203165290	1	+	26780180	A375	viability (Avana lentiGuide)	GATGGTGGTGACCCCCCGGAGGG	ADORA1	ENSG00000163485	9.42688857238064	[]	[]	6	hSpCas9	negative selection	3585802
203128845	203128868	1	-	26780180	A375	viability (Avana lentiGuide)	TGGAAAGCTGAGATGGAGGGCGG	ADORA1	ENSG00000163485	-1.69161357328968	[]	[]	-3	hSpCas9	negative selection	3585803
203129159	203129182	1	-	26780180	A375	viability (Avana lentiGuide)	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	5.76221197606285	[]	[]	5	hSpCas9	negative selection	3585804
203129032	203129055	1	-	26780180	A375	viability (Avana lentiGuide)	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	1.48375183640784	[]	[]	1	hSpCas9	negative selection	3585805
203128919	203128942	1	+	26780180	A375	viability (Avana lentiGuide)	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	12.4203769332956	[]	[]	7	hSpCas9	negative selection	3585806
203129081	203129104	1	-	26780180	A375	viability (Avana lentiGuide)	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	4.17314658765638	[]	[]	4	hSpCas9	negative selection	3585807
203165267	203165290	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGTGGTGACCCCCCGGAGGG	ADORA1	ENSG00000163485	0.2205361782148893	[4]	[5,4]	6	hSpCas9	positive selection	3694461
203128845	203128868	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGAAAGCTGAGATGGAGGGCGG	ADORA1	ENSG00000163485	0.1572800243492584	[5]	[6,6]	4	hSpCas9	positive selection	3694462
203129159	203129182	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.22028359177961557	[4]	[5,4]	6	hSpCas9	positive selection	3694463
203129032	203129055	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.1454701529064481	[5]	[5,5]	4	hSpCas9	positive selection	3694464
203128919	203128942	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.016244779143356702	[3]	[3,3]	0	hSpCas9	positive selection	3694465
203129081	203129104	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.2772695351902462	[4]	[5,5]	7	hSpCas9	positive selection	3694466
203165267	203165290	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGTGGTGACCCCCCGGAGGG	ADORA1	ENSG00000163485	-0.1129782574161231	[4]	[4,3]	-1	hSpCas9	positive selection	3803068
203128845	203128868	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGAAAGCTGAGATGGAGGGCGG	ADORA1	ENSG00000163485	0.03824525126957262	[6]	[6,4]	0	hSpCas9	positive selection	3803069
203129159	203129182	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.017464825921160665	[4]	[5,1]	0	hSpCas9	positive selection	3803070
203129032	203129055	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.36912913738861064	[5]	[6,5]	9	hSpCas9	positive selection	3803071
203128919	203128942	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	-0.0549408054317148	[4]	[4,3]	-1	hSpCas9	positive selection	3803072
203129081	203129104	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.0021518826447810557	[5]	[4,3]	0	hSpCas9	positive selection	3803073
203165413	203165436	1	-	26780180	A375	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	1.00107123582192	[]	[]	4	hSpCas9	negative selection	3911527
203128973	203128996	1	+	26780180	A375	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.128477622593221	[]	[]	0	hSpCas9	negative selection	3911528
203165889	203165912	1	-	26780180	A375	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.261663434531107	[]	[]	0	hSpCas9	negative selection	3911529
203129081	203129104	1	-	26780180	A375	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.764666653388834	[]	[]	3	hSpCas9	negative selection	3911530
203165577	203165600	1	+	26780180	A375	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	1.08012305843757	[]	[]	5	hSpCas9	negative selection	3911531
203165744	203165767	1	-	26780180	A375	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.713945467816025	[]	[]	2	hSpCas9	negative selection	3911532
203165413	203165436	1	-	26780180	HT29	viability (GeCKOv2 library)	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.110409969624353	[]	[]	0	hSpCas9	negative selection	4019493
203128973	203128996	1	+	26780180	HT29	viability (GeCKOv2 library)	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.339727737300509	[]	[]	0	hSpCas9	negative selection	4019494
203165889	203165912	1	-	26780180	HT29	viability (GeCKOv2 library)	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.495793626368085	[]	[]	1	hSpCas9	negative selection	4019495
203129081	203129104	1	-	26780180	HT29	viability (GeCKOv2 library)	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.199234733994191	[]	[]	0	hSpCas9	negative selection	4019496
203165577	203165600	1	+	26780180	HT29	viability (GeCKOv2 library)	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	1.16517859215052	[]	[]	5	hSpCas9	negative selection	4019497
203165744	203165767	1	-	26780180	HT29	viability (GeCKOv2 library)	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	1.25233801401164	[]	[]	6	hSpCas9	negative selection	4019498
203128883	203128906	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	-0.03267997070846377	[3]	[2,2]	-1	hSpCas9	positive selection	4128927
203129081	203129104	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.6530333460240905	[3]	[1,0]	-9	hSpCas9	positive selection	4128938
203165577	203165600	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.6954748790443116	[2]	[0,0]	-9	hSpCas9	positive selection	4128949
203129143	203129166	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	0.1582636796977825	[4]	[2,3]	4	hSpCas9	positive selection	4128960
203128883	203128906	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCGAGGTGCTCATCGCCCTGG	ADORA1	ENSG00000163485	0.2058542294926169	[3]	[1,3,0,0]	1	hSpCas9	positive selection	4192949
203129081	203129104	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.775440853138385	[3]	[0,3,2,3]	5	hSpCas9	positive selection	4192960
203165577	203165600	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	1.4072544801094828	[0]	[1,2,2,0]	9	hSpCas9	positive selection	4192971
203129143	203129166	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGCTGTGGACCGCTACCTCCGG	ADORA1	ENSG00000163485	0.6977257072641488	[4]	[0,1,3,3]	4	hSpCas9	positive selection	4192982
203165577	203165600	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.6055345295596652	[1]	[1,0]	-8	hSpCas9	positive selection	4254713
203165413	203165436	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.37517020489598624	[3]	[3,3]	7	hSpCas9	positive selection	4254714
203128973	203128996	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.4435757075194015	[4]	[4,4]	8	hSpCas9	positive selection	4254715
203129081	203129104	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.11401980658030236	[4]	[4,2]	2	hSpCas9	positive selection	4318995
203165889	203165912	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.19015943467456198	[1]	[1,0]	-4	hSpCas9	positive selection	4318996
203165744	203165767	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.20236565978088722	[3]	[3,2]	4	hSpCas9	positive selection	4318997
203129035	203129057	1	+	27760321	OCIAML3	viability	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	1.0012490473969688	[347,289]	[449,558]	9	hSpCas9	negative selection	4376466
203129162	203129184	1	-	27760321	OCIAML3	viability	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	-0.5649278540813005	[371,221]	[165,138]	-5	hSpCas9	negative selection	4376467
203129175	203129197	1	-	27760321	OCIAML3	viability	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	0.09599957585364005	[587,479]	[388,515]	1	hSpCas9	negative selection	4376468
203165271	203165293	1	+	27760321	OCIAML3	viability	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.864122789073019	[264,214]	[305,383]	8	hSpCas9	negative selection	4376469
203165360	203165382	1	+	27760321	OCIAML3	viability	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	-0.17517559100658775	[350,368]	[218,291]	-2	hSpCas9	negative selection	4376470
203129035	203129057	1	+	27760321	OCIAML2	viability	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.21413340658903723	[347,289]	[241,371]	3	hSpCas9	negative selection	4459929
203129162	203129184	1	-	27760321	OCIAML2	viability	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	-0.3893934846368038	[371,221]	[146,223]	-4	hSpCas9	negative selection	4459930
203129175	203129197	1	-	27760321	OCIAML2	viability	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	-1.3384407937067684	[587,479]	[194,136]	-8	hSpCas9	negative selection	4459931
203165271	203165293	1	+	27760321	OCIAML2	viability	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.4872727531833721	[264,214]	[268,272]	6	hSpCas9	negative selection	4459932
203165360	203165382	1	+	27760321	OCIAML2	viability	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.2044019130286555	[350,368]	[307,375]	2	hSpCas9	negative selection	4459933
203129035	203129057	1	+	27760321	MV411	viability	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.785718434158786	[347,289]	[348,379]	6	hSpCas9	negative selection	4543392
203129162	203129184	1	-	27760321	MV411	viability	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	-0.8285927392400025	[371,221]	[147,48]	-5	hSpCas9	negative selection	4543393
203129175	203129197	1	-	27760321	MV411	viability	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	-0.4471688730093132	[587,479]	[223,306]	-3	hSpCas9	negative selection	4543394
203165271	203165293	1	+	27760321	MV411	viability	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	1.4217435860084127	[264,214]	[505,295]	8	hSpCas9	negative selection	4543395
203165360	203165382	1	+	27760321	MV411	viability	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.4897422291884222	[350,368]	[294,395]	3	hSpCas9	negative selection	4543396
203129035	203129057	1	+	27760321	HL60	viability	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.18584647706592072	[347,289]	[333,253]	2	hSpCas9	negative selection	4626855
203129162	203129184	1	-	27760321	HL60	viability	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	0.49778133334318786	[371,221]	[455,209]	6	hSpCas9	negative selection	4626856
203129175	203129197	1	-	27760321	HL60	viability	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	0.038009201026043216	[587,479]	[498,388]	0	hSpCas9	negative selection	4626857
203165271	203165293	1	+	27760321	HL60	viability	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	-0.3948733620096371	[264,214]	[158,136]	-4	hSpCas9	negative selection	4626858
203165360	203165382	1	+	27760321	HL60	viability	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	-0.20902017216946928	[350,368]	[214,298]	-2	hSpCas9	negative selection	4626859
203129035	203129057	1	+	27760321	HT1080	viability	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	2.116675419393679	[289,226]	[650,222]	9	hSpCas9	negative selection	4710318
203129162	203129184	1	-	27760321	HT1080	viability	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	-0.1351104790786184	[221,172]	[63,79]	0	hSpCas9	negative selection	4710319
203129175	203129197	1	-	27760321	HT1080	viability	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	-0.9667429848512398	[479,374]	[47,129]	-4	hSpCas9	negative selection	4710320
203165271	203165293	1	+	27760321	HT1080	viability	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.5823072621678027	[214,167]	[97,131]	3	hSpCas9	negative selection	4710321
203165360	203165382	1	+	27760321	HT1080	viability	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.6540283007793273	[368,287]	[256,149]	3	hSpCas9	negative selection	4710322
203129035	203129057	1	+	27760321	HT29	viability after 7 days	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.6691170249845813	[289,226]	[549,349,682]	8	hSpCas9	negative selection	4793781
203129162	203129184	1	-	27760321	HT29	viability after 7 days	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	0.891574456757378	[221,172]	[262,750,371]	9	hSpCas9	negative selection	4793782
203129175	203129197	1	-	27760321	HT29	viability after 7 days	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	0.6637250406039502	[479,374]	[882,991,741]	8	hSpCas9	negative selection	4793783
203165271	203165293	1	+	27760321	HT29	viability after 7 days	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.16965149682740177	[214,167]	[439,240,175]	2	hSpCas9	negative selection	4793784
203165360	203165382	1	+	27760321	HT29	viability after 7 days	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	-0.35759314328139447	[368,287]	[310,415,260]	-5	hSpCas9	negative selection	4793785
203129035	203129057	1	+	27760321	HT29	viability after 25 days	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.734025709972197	[289,226]	[413,516,553]	8	hSpCas9	negative selection	4877244
203129162	203129184	1	-	27760321	HT29	viability after 25 days	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	0.23375402886468033	[221,172]	[89,328,401]	2	hSpCas9	negative selection	4877245
203129175	203129197	1	-	27760321	HT29	viability after 25 days	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	0.559484597949186	[479,374]	[583,825,761]	6	hSpCas9	negative selection	4877246
203165271	203165293	1	+	27760321	HT29	viability after 25 days	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.31711185102199246	[214,167]	[248,280,290]	3	hSpCas9	negative selection	4877247
203165360	203165382	1	+	27760321	HT29	viability after 25 days	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.23974502976174825	[368,287]	[387,601,330]	2	hSpCas9	negative selection	4877248
203129035	203129057	1	+	27760321	HT29	viability after 22 days	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.4373642168433227	[289,226]	[378,315,520]	5	hSpCas9	negative selection	4960707
203129162	203129184	1	-	27760321	HT29	viability after 22 days	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	0.5058102237556246	[221,172]	[321,382,266]	5	hSpCas9	negative selection	4960708
203129175	203129197	1	-	27760321	HT29	viability after 22 days	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	0.7736967537120257	[479,374]	[982,720,826]	8	hSpCas9	negative selection	4960709
203165271	203165293	1	+	27760321	HT29	viability after 22 days	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.6336220044106311	[214,167]	[442,321,261]	7	hSpCas9	negative selection	4960710
203165360	203165382	1	+	27760321	HT29	viability after 22 days	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.23845195977617772	[368,287]	[435,392,515]	2	hSpCas9	negative selection	4960711
203129035	203129057	1	+	27760321	HT29	viability after 19 days	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.42517171228652145	[289,226]	[401,328,457]	4	hSpCas9	negative selection	5044170
203129162	203129184	1	-	27760321	HT29	viability after 19 days	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	-0.0012728614722478104	[221,172]	[273,131,273]	0	hSpCas9	negative selection	5044171
203129175	203129197	1	-	27760321	HT29	viability after 19 days	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	0.5505775113086443	[479,374]	[863,463,830]	5	hSpCas9	negative selection	5044172
203165271	203165293	1	+	27760321	HT29	viability after 19 days	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	-0.1306140960659602	[214,167]	[355,129,132]	-1	hSpCas9	negative selection	5044173
203165360	203165382	1	+	27760321	HT29	viability after 19 days	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.08407410885095457	[368,287]	[552,482,182]	0	hSpCas9	negative selection	5044174
203129035	203129057	1	+	27760321	HT29	viability after 16 days	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.5084913002046367	[289,226]	[482,264,496]	6	hSpCas9	negative selection	5127633
203129162	203129184	1	-	27760321	HT29	viability after 16 days	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	0.7887186736846513	[221,172]	[319,464,351]	8	hSpCas9	negative selection	5127634
203129175	203129197	1	-	27760321	HT29	viability after 16 days	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	0.3991712795319695	[479,374]	[500,591,787]	4	hSpCas9	negative selection	5127635
203165271	203165293	1	+	27760321	HT29	viability after 16 days	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.6363153268943191	[214,167]	[376,188,440]	7	hSpCas9	negative selection	5127636
203165360	203165382	1	+	27760321	HT29	viability after 16 days	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.12184480184882282	[368,287]	[455,360,388]	1	hSpCas9	negative selection	5127637
203129035	203129057	1	+	27760321	HT29	viability after 13 days	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.6609491142331003	[289,226]	[550,252,609]	8	hSpCas9	negative selection	5211096
203129162	203129184	1	-	27760321	HT29	viability after 13 days	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	0.5474218367109466	[221,172]	[264,360,375]	7	hSpCas9	negative selection	5211097
203129175	203129197	1	-	27760321	HT29	viability after 13 days	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	0.6047517841458975	[479,374]	[742,703,811]	7	hSpCas9	negative selection	5211098
203165271	203165293	1	+	27760321	HT29	viability after 13 days	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.4548459952068598	[214,167]	[143,364,398]	6	hSpCas9	negative selection	5211099
203165360	203165382	1	+	27760321	HT29	viability after 13 days	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.021180147035163355	[368,287]	[428,377,354]	0	hSpCas9	negative selection	5211100
203129035	203129057	1	+	27760321	HT29	viability after 10 days	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.37752493644893687	[289,226]	[382,414,458]	5	hSpCas9	negative selection	5294559
203129162	203129184	1	-	27760321	HT29	viability after 10 days	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	0.5789355862942211	[221,172]	[524,320,259]	7	hSpCas9	negative selection	5294560
203129175	203129197	1	-	27760321	HT29	viability after 10 days	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	0.46961148782429374	[479,374]	[677,578,950]	6	hSpCas9	negative selection	5294561
203165271	203165293	1	+	27760321	HT29	viability after 10 days	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.46843126150256154	[214,167]	[322,364,305]	6	hSpCas9	negative selection	5294562
203165360	203165382	1	+	27760321	HT29	viability after 10 days	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.29617865002866844	[368,287]	[506,686,325]	4	hSpCas9	negative selection	5294563
203129035	203129057	1	+	27760321	MOLM13	viability	TCGCCATCCTCATCAACATTGG	ADORA1	ENSG00000163485	0.5529961642414979	[347,289]	[303,227]	4	hSpCas9	negative selection	5378022
203129162	203129184	1	-	27760321	MOLM13	viability	CCGGAGAGGGATCTTGACCCGG	ADORA1	ENSG00000163485	-0.8548580860677741	[371,221]	[177,16]	-5	hSpCas9	negative selection	5378023
203129175	203129197	1	-	27760321	MOLM13	viability	CGCTGTGGACTCACCGGAGAGG	ADORA1	ENSG00000163485	-0.027982855299763326	[587,479]	[461,150]	0	hSpCas9	negative selection	5378024
203165271	203165293	1	+	27760321	MOLM13	viability	GTGGTGACCCCCCGGAGGGCGG	ADORA1	ENSG00000163485	0.6518259463590677	[264,214]	[330,109]	4	hSpCas9	negative selection	5378025
203165360	203165382	1	+	27760321	MOLM13	viability	CAATCTGAGTGCGGTGGAGCGG	ADORA1	ENSG00000163485	0.8270261508877704	[350,368]	[479,261]	6	hSpCas9	negative selection	5378026
203128649	203128672	1	+	27661255	K562	viability	GGTGCCCCTCCAGCCTGGGTAGG	ADORA1	ENSG00000163485	-0.004173651229026298	[628,715]	[616,463]	0	dCas9-KRAB	negative selection	5461144
203128682	203128705	1	+	27661255	K562	viability	GACAAGTGGGACACATCACAGGG	ADORA1	ENSG00000163485	0.07337153827879073	[1597,1327]	[1291,1183]	2	dCas9-KRAB	negative selection	5461145
203128323	203128346	1	-	27661255	K562	viability	GCTGGGCTCTGGACAACGCGCGG	ADORA1	ENSG00000163485	0.2023309919849543	[569,611]	[596,495]	7	dCas9-KRAB	negative selection	5461146
203128345	203128368	1	-	27661255	K562	viability	GGGCCGCGCGCGGTAGGGCTGGG	ADORA1	ENSG00000163485	0.046303773150348726	[1124,1418]	[1215,898]	1	dCas9-KRAB	negative selection	5461147
203165577	203165600	1	+	27260156	BXPC3	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.39742978986892097	[195]	[350,263,220,226]	8	hSpCas9	negative selection	5527173
203165413	203165436	1	-	27260156	BXPC3	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.44645712272275384	[693]	[1015,977,898,1059]	8	hSpCas9	negative selection	5527174
203128973	203128996	1	+	27260156	BXPC3	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.5091538354568654	[1191]	[1490,1741,1640,2304]	9	hSpCas9	negative selection	5527175
203129081	203129104	1	-	27260156	BXPC3	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.27838884488825233	[1187]	[1403,1463,1638,1526]	6	hSpCas9	negative selection	5591455
203165889	203165912	1	-	27260156	BXPC3	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.3920898960949799	[83]	[130,105,88,134]	8	hSpCas9	negative selection	5591456
203165744	203165767	1	-	27260156	BXPC3	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.005380343460162251	[581]	[539,700,512,695]	0	hSpCas9	negative selection	5591457
203165577	203165600	1	+	27260156	A673	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.31036458730716077	[195]	[339,226,267,341]	7	hSpCas9	negative selection	5648424
203165413	203165436	1	-	27260156	A673	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.36782071547067285	[693]	[1210,952,1105,1045]	8	hSpCas9	negative selection	5648425
203128973	203128996	1	+	27260156	A673	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.5657372844105806	[1191]	[2364,1789,2227,2122]	9	hSpCas9	negative selection	5648426
203129081	203129104	1	-	27260156	A673	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.02549797803101095	[1187]	[1651,1319,1314,1550]	0	hSpCas9	negative selection	5712706
203165889	203165912	1	-	27260156	A673	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.45166819535646674	[83]	[104,128,183,128]	8	hSpCas9	negative selection	5712707
203165744	203165767	1	-	27260156	A673	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.12085238557217498	[581]	[797,597,496,699]	-3	hSpCas9	negative selection	5712708
203165577	203165600	1	+	27260156	A375	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.5276021238573948	[195]	[253,398,309,360]	7	hSpCas9	negative selection	5769675
203165413	203165436	1	-	27260156	A375	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.16151505461446636	[693]	[874,1291,775,751]	2	hSpCas9	negative selection	5769676
203128973	203128996	1	+	27260156	A375	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.7325703489289075	[1191]	[2095,2782,2299,2148]	9	hSpCas9	negative selection	5769677
203129081	203129104	1	-	27260156	A375	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.05531721915177057	[1187]	[1605,1527,1431,1233]	0	hSpCas9	negative selection	5833957
203165889	203165912	1	-	27260156	A375	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.7204574036680773	[83]	[120,145,209,165]	9	hSpCas9	negative selection	5833958
203165744	203165767	1	-	27260156	A375	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.2499104405267473	[581]	[477,645,708,472]	-4	hSpCas9	negative selection	5833959
203165577	203165600	1	+	27260156	COLO741	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.503673700628217	[195]	[354,320,385]	8	hSpCas9	negative selection	5890926
203165413	203165436	1	-	27260156	COLO741	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.46300784311366305	[693]	[1331,1046,1288]	8	hSpCas9	negative selection	5890927
203128973	203128996	1	+	27260156	COLO741	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.5626799447887667	[1191]	[2620,2568,1631]	9	hSpCas9	negative selection	5890928
203129081	203129104	1	-	27260156	COLO741	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.06468158301585225	[1187]	[1486,1515,1357]	-1	hSpCas9	negative selection	5955208
203165889	203165912	1	-	27260156	COLO741	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.1721437429811803	[83]	[162,109,94]	3	hSpCas9	negative selection	5955209
203165744	203165767	1	-	27260156	COLO741	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.08626250063108137	[581]	[848,781,743]	1	hSpCas9	negative selection	5955210
203165577	203165600	1	+	27260156	CAL120	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.3349996958356637	[195]	[558,225,177]	5	hSpCas9	negative selection	6012177
203165413	203165436	1	-	27260156	CAL120	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.3490172993674139	[693]	[1054,987,1246]	5	hSpCas9	negative selection	6012178
203128973	203128996	1	+	27260156	CAL120	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.3094615458912604	[1191]	[2080,1724,1745]	4	hSpCas9	negative selection	6012179
203129081	203129104	1	-	27260156	CAL120	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.10376164392948195	[1187]	[1583,1570,1608]	1	hSpCas9	negative selection	6076459
203165889	203165912	1	-	27260156	CAL120	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.3576197178505849	[83]	[89,75,79]	-5	hSpCas9	negative selection	6076460
203165744	203165767	1	-	27260156	CAL120	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.3208044345573421	[581]	[741,571,451]	-5	hSpCas9	negative selection	6076461
203165577	203165600	1	+	27260156	CADOES1	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.06616831924416999	[195]	[138,185,135,237]	-1	hSpCas9	negative selection	6133428
203165413	203165436	1	-	27260156	CADOES1	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.18103208255572323	[693]	[631,731,735,830]	3	hSpCas9	negative selection	6133429
203128973	203128996	1	+	27260156	CADOES1	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.5619231666054911	[1191]	[1411,1674,1746,1715]	8	hSpCas9	negative selection	6133430
203129081	203129104	1	-	27260156	CADOES1	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.11317019360459812	[1187]	[910,1048,1117,1007]	-2	hSpCas9	negative selection	6197710
203165889	203165912	1	-	27260156	CADOES1	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.5936022823792224	[83]	[170,95,70,133]	8	hSpCas9	negative selection	6197711
203165744	203165767	1	-	27260156	CADOES1	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.08882936729799884	[581]	[475,427,616,514]	-1	hSpCas9	negative selection	6197712
203165577	203165600	1	+	27260156	EWS502	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.04563801847029736	[195]	[275,195,142,234]	0	hSpCas9	negative selection	6254679
203165413	203165436	1	-	27260156	EWS502	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.49755701919897466	[693]	[1100,978,985,1077]	8	hSpCas9	negative selection	6254680
203128973	203128996	1	+	27260156	EWS502	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.6817010530818295	[1191]	[2087,1885,2071,2046]	9	hSpCas9	negative selection	6254681
203129081	203129104	1	-	27260156	EWS502	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.19845385899162782	[1187]	[1385,1519,1366,1503]	3	hSpCas9	negative selection	6318961
203165889	203165912	1	-	27260156	EWS502	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.01955246299197011	[83]	[79,68,106,107]	0	hSpCas9	negative selection	6318962
203165744	203165767	1	-	27260156	EWS502	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.15566837542934028	[581]	[484,579,492,667]	-3	hSpCas9	negative selection	6318963
203165577	203165600	1	+	27260156	EW8	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.21747343610334546	[195]	[153,182,170,228]	4	hSpCas9	negative selection	6375930
203165413	203165436	1	-	27260156	EW8	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.44781060076546275	[693]	[916,757,593,842]	7	hSpCas9	negative selection	6375931
203128973	203128996	1	+	27260156	EW8	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.5197728337694991	[1191]	[1374,1987,1033,1200]	8	hSpCas9	negative selection	6375932
203129081	203129104	1	-	27260156	EW8	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.05471499916405209	[1187]	[1159,1181,744,971]	1	hSpCas9	negative selection	6440212
203165889	203165912	1	-	27260156	EW8	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.7121014498950162	[83]	[141,139,41,136]	9	hSpCas9	negative selection	6440213
203165744	203165767	1	-	27260156	EW8	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.09337874358237339	[581]	[595,441,396,356]	-2	hSpCas9	negative selection	6440214
203165577	203165600	1	+	27260156	CORL105	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.029529765510339256	[195]	[308,139,207,243]	0	hSpCas9	negative selection	6497181
203165413	203165436	1	-	27260156	CORL105	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.46880852401194595	[693]	[933,1087,1208,1272]	8	hSpCas9	negative selection	6497182
203128973	203128996	1	+	27260156	CORL105	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.46134945731976096	[1191]	[2286,1644,1990,1790]	8	hSpCas9	negative selection	6497183
203129081	203129104	1	-	27260156	CORL105	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.22614359677667628	[1187]	[1602,1735,1801,1390]	4	hSpCas9	negative selection	6561463
203165889	203165912	1	-	27260156	CORL105	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.40412080211978285	[83]	[37,134,74,46]	-6	hSpCas9	negative selection	6561464
203165744	203165767	1	-	27260156	CORL105	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.04235788510916255	[581]	[717,604,765,576]	-1	hSpCas9	negative selection	6561465
203165577	203165600	1	+	27260156	HS294T	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.582707512807251	[195]	[153,76,115,101]	7	hSpCas9	negative selection	6618432
203165413	203165436	1	-	27260156	HS294T	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.6521074314249276	[693]	[307,361,418,646]	8	hSpCas9	negative selection	6618433
203128973	203128996	1	+	27260156	HS294T	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	1.1153746924811343	[1191]	[896,926,840,1405]	9	hSpCas9	negative selection	6618434
203129081	203129104	1	-	27260156	HS294T	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.01851763125870831	[1187]	[412,433,431,610]	0	hSpCas9	negative selection	6682714
203165889	203165912	1	-	27260156	HS294T	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.22294810938873333	[83]	[22,9,52,25]	-3	hSpCas9	negative selection	6682715
203165744	203165767	1	-	27260156	HS294T	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.29625233488963904	[581]	[135,172,191,246]	-4	hSpCas9	negative selection	6682716
203165577	203165600	1	+	27260156	HCC44	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.16432128038006577	[195]	[210,123,291,381]	2	hSpCas9	negative selection	6739683
203165413	203165436	1	-	27260156	HCC44	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.4885069598659515	[693]	[896,764,1552,1281]	7	hSpCas9	negative selection	6739684
203128973	203128996	1	+	27260156	HCC44	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.5738035910083212	[1191]	[2164,1744,2215,1972]	8	hSpCas9	negative selection	6739685
203129081	203129104	1	-	27260156	HCC44	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.06708979886860389	[1187]	[1465,849,1923,1547]	1	hSpCas9	negative selection	6803965
203165889	203165912	1	-	27260156	HCC44	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.6105592225507619	[83]	[115,172,121,156]	8	hSpCas9	negative selection	6803966
203165744	203165767	1	-	27260156	HCC44	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.15398005010350835	[581]	[885,684,956,463]	2	hSpCas9	negative selection	6803967
203165577	203165600	1	+	27260156	G402	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.6001651532043867	[195]	[429,190,347,473]	7	hSpCas9	negative selection	6860934
203165413	203165436	1	-	27260156	G402	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.047637625475052126	[693]	[1258,1066,613,635]	0	hSpCas9	negative selection	6860935
203128973	203128996	1	+	27260156	G402	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.8075065579423	[1191]	[2496,2076,2037,3479]	8	hSpCas9	negative selection	6860936
203129081	203129104	1	-	27260156	G402	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.10384162493177795	[1187]	[2140,1424,1779,983]	1	hSpCas9	negative selection	6925216
203165889	203165912	1	-	27260156	G402	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.2729904440702762	[83]	[79,110,46,100]	-3	hSpCas9	negative selection	6925217
203165744	203165767	1	-	27260156	G402	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.25199183041222745	[581]	[895,1051,525,920]	3	hSpCas9	negative selection	6925218
203165577	203165600	1	+	27260156	L33	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.435305377411659	[195]	[175,125,241,194]	8	hSpCas9	negative selection	6982185
203165413	203165436	1	-	27260156	L33	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.2345515989908633	[693]	[770,308,596,792]	5	hSpCas9	negative selection	6982186
203128973	203128996	1	+	27260156	L33	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.3363060743800317	[1191]	[1784,590,817,1482]	7	hSpCas9	negative selection	6982187
203129081	203129104	1	-	27260156	L33	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.08268304751460254	[1187]	[1065,525,908,1241]	1	hSpCas9	negative selection	7046467
203165889	203165912	1	-	27260156	L33	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.7443526174890369	[83]	[48,18,35,47]	-9	hSpCas9	negative selection	7046468
203165744	203165767	1	-	27260156	L33	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.08475554876267757	[581]	[521,188,359,638]	-2	hSpCas9	negative selection	7046469
203165577	203165600	1	+	27260156	K562	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.31722294815663565	[195]	[270,258,308,52]	4	hSpCas9	negative selection	7103436
203165413	203165436	1	-	27260156	K562	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.3781147852811354	[693]	[665,1070,772,702]	5	hSpCas9	negative selection	7103437
203128973	203128996	1	+	27260156	K562	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.7404191803445799	[1191]	[1793,1812,1634,1817]	8	hSpCas9	negative selection	7103438
203129081	203129104	1	-	27260156	K562	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.11505529591787877	[1187]	[1387,975,1032,1172]	1	hSpCas9	negative selection	7167718
203165889	203165912	1	-	27260156	K562	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.21940009915621328	[83]	[59,79,152,54]	2	hSpCas9	negative selection	7167719
203165744	203165767	1	-	27260156	K562	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.18678306786300142	[581]	[789,534,838,239]	2	hSpCas9	negative selection	7167720
203165577	203165600	1	+	27260156	HT29	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.3171210663397963	[195]	[348,323,261,260]	6	hSpCas9	negative selection	7224687
203165413	203165436	1	-	27260156	HT29	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.4030644134154585	[693]	[1024,788,1425,1171]	7	hSpCas9	negative selection	7224688
203128973	203128996	1	+	27260156	HT29	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.44966211379555143	[1191]	[1959,2324,1911,1759]	8	hSpCas9	negative selection	7224689
203129081	203129104	1	-	27260156	HT29	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.18024816128988363	[1187]	[1672,2052,1586,1300]	3	hSpCas9	negative selection	7288969
203165889	203165912	1	-	27260156	HT29	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.170576480395217	[83]	[136,122,92,108]	3	hSpCas9	negative selection	7288970
203165744	203165767	1	-	27260156	HT29	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.047005116938533265	[581]	[834,527,609,750]	-1	hSpCas9	negative selection	7288971
203165577	203165600	1	+	27260156	MHHES1	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.042936759242677036	[195]	[289,165,309,156]	0	hSpCas9	negative selection	7345938
203165413	203165436	1	-	27260156	MHHES1	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.26386790024080076	[693]	[715,1294,935,821]	5	hSpCas9	negative selection	7345939
203128973	203128996	1	+	27260156	MHHES1	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.6698531088122057	[1191]	[2513,2338,2533,1359]	9	hSpCas9	negative selection	7345940
203129081	203129104	1	-	27260156	MHHES1	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.07213623216479581	[1187]	[1533,1387,1336,927]	-1	hSpCas9	negative selection	7410220
203165889	203165912	1	-	27260156	MHHES1	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.6382582693276251	[83]	[22,73,102,42]	-8	hSpCas9	negative selection	7410221
203165744	203165767	1	-	27260156	MHHES1	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.5064807809617436	[581]	[454,445,542,402]	-7	hSpCas9	negative selection	7410222
203165577	203165600	1	+	27260156	MEWO	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.4774472669941159	[195]	[298,319,154]	8	hSpCas9	negative selection	7467189
203165413	203165436	1	-	27260156	MEWO	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.3305302007848757	[693]	[840,802,809]	7	hSpCas9	negative selection	7467190
203128973	203128996	1	+	27260156	MEWO	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.44161024594860576	[1191]	[1594,1499,1463]	8	hSpCas9	negative selection	7467191
203129081	203129104	1	-	27260156	MEWO	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.13510481767256977	[1187]	[1073,1018,954]	-3	hSpCas9	negative selection	7531471
203165889	203165912	1	-	27260156	MEWO	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.34270028354427984	[83]	[98,63,135]	7	hSpCas9	negative selection	7531472
203165744	203165767	1	-	27260156	MEWO	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.19377814505898033	[581]	[529,378,529]	-4	hSpCas9	negative selection	7531473
203165577	203165600	1	+	27260156	LNCAPCLONEFGC	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.5217360182169696	[195]	[109,330,367,224]	7	hSpCas9	negative selection	7588440
203165413	203165436	1	-	27260156	LNCAPCLONEFGC	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.3933218542007113	[693]	[843,572,1178,774]	6	hSpCas9	negative selection	7588441
203128973	203128996	1	+	27260156	LNCAPCLONEFGC	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.7025394637940909	[1191]	[1684,1647,1748,1952]	9	hSpCas9	negative selection	7588442
203129081	203129104	1	-	27260156	LNCAPCLONEFGC	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.15805328294773968	[1187]	[1238,1155,1352,1078]	2	hSpCas9	negative selection	7652722
203165889	203165912	1	-	27260156	LNCAPCLONEFGC	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.6360468655793892	[83]	[72,100,185,124]	8	hSpCas9	negative selection	7652723
203165744	203165767	1	-	27260156	LNCAPCLONEFGC	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.04007325386554278	[581]	[543,410,868,400]	0	hSpCas9	negative selection	7652724
203165577	203165600	1	+	27260156	PANC0327	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.023744247749007075	[195]	[135,172,222,149]	0	hSpCas9	negative selection	7709691
203165413	203165436	1	-	27260156	PANC0327	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.5623369382764025	[693]	[1089,930,794,836]	7	hSpCas9	negative selection	7709692
203128973	203128996	1	+	27260156	PANC0327	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.42944789608024414	[1191]	[1792,1125,1277,1574]	6	hSpCas9	negative selection	7709693
203129081	203129104	1	-	27260156	PANC0327	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.3053680996991295	[1187]	[1535,981,1121,1635]	4	hSpCas9	negative selection	7773973
203165889	203165912	1	-	27260156	PANC0327	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.28230820689413383	[83]	[53,36,92,63]	-4	hSpCas9	negative selection	7773974
203165744	203165767	1	-	27260156	PANC0327	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.4484718990512703	[581]	[504,352,344,325]	-6	hSpCas9	negative selection	7773975
203165577	203165600	1	+	27260156	NCIH2009	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.3525991458467288	[195]	[553,281,253]	5	hSpCas9	negative selection	7830942
203165413	203165436	1	-	27260156	NCIH2009	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.36900836321748043	[693]	[1502,1370,927]	5	hSpCas9	negative selection	7830943
203128973	203128996	1	+	27260156	NCIH2009	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.8630379579864718	[1191]	[3511,2905,2761]	9	hSpCas9	negative selection	7830944
203129081	203129104	1	-	27260156	NCIH2009	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.3239936378038266	[1187]	[2743,1769,1852]	4	hSpCas9	negative selection	7895224
203165889	203165912	1	-	27260156	NCIH2009	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.24247985229707236	[83]	[163,57,88]	-3	hSpCas9	negative selection	7895225
203165744	203165767	1	-	27260156	NCIH2009	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.08919662696023939	[581]	[1174,744,736]	1	hSpCas9	negative selection	7895226
203165577	203165600	1	+	27260156	NCIH1373	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.8198269007437882	[195]	[222,530,393,93]	7	hSpCas9	negative selection	7952193
203165413	203165436	1	-	27260156	NCIH1373	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.7998373805507759	[693]	[2444,686,1505,259]	7	hSpCas9	negative selection	7952194
203128973	203128996	1	+	27260156	NCIH1373	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	1.020216649613202	[1191]	[3846,2077,2872,588]	9	hSpCas9	negative selection	7952195
203129081	203129104	1	-	27260156	NCIH1373	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.1534712813097212	[1187]	[1233,1184,1393,561]	1	hSpCas9	negative selection	8016475
203165889	203165912	1	-	27260156	NCIH1373	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.7763461294949736	[83]	[113,59,29,5]	-7	hSpCas9	negative selection	8016476
203165744	203165767	1	-	27260156	NCIH1373	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.4007060951045687	[581]	[496,444,359,181]	-4	hSpCas9	negative selection	8016477
203165577	203165600	1	+	27260156	PATU8902	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.05561216270715108	[195]	[292,283,173,327]	0	hSpCas9	negative selection	8073444
203165413	203165436	1	-	27260156	PATU8902	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.691987097101634	[693]	[1566,1357,1353,2067]	7	hSpCas9	negative selection	8073445
203128973	203128996	1	+	27260156	PATU8902	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.9830060274688757	[1191]	[3359,4455,1819,3921]	9	hSpCas9	negative selection	8073446
203129081	203129104	1	-	27260156	PATU8902	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.3792417564519759	[1187]	[1751,1947,1765,3375]	4	hSpCas9	negative selection	8137726
203165889	203165912	1	-	27260156	PATU8902	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.8255658671513562	[83]	[60,117,24,70]	-6	hSpCas9	negative selection	8137727
203165744	203165767	1	-	27260156	PATU8902	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.26602628249167654	[581]	[1113,1162,644,1063]	2	hSpCas9	negative selection	8137728
203165577	203165600	1	+	27260156	PANC1	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.5463632095760275	[195]	[381,297,188,135]	8	hSpCas9	negative selection	8194695
203165413	203165436	1	-	27260156	PANC1	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.4521384521530041	[693]	[856,966,961,539]	7	hSpCas9	negative selection	8194696
203128973	203128996	1	+	27260156	PANC1	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.5858436791304003	[1191]	[1407,2133,1354,1374]	8	hSpCas9	negative selection	8194697
203129081	203129104	1	-	27260156	PANC1	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.38230969115732893	[1187]	[1137,1544,1372,1295]	6	hSpCas9	negative selection	8258977
203165889	203165912	1	-	27260156	PANC1	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.08536481848753441	[83]	[44,77,144,14]	-1	hSpCas9	negative selection	8258978
203165744	203165767	1	-	27260156	PANC1	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.23905123132703104	[581]	[534,489,870,458]	4	hSpCas9	negative selection	8258979
203165577	203165600	1	+	27260156	PANC0813	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.22780937252313027	[195]	[235,206,218,404]	3	hSpCas9	negative selection	8315946
203165413	203165436	1	-	27260156	PANC0813	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.5621557393101244	[693]	[1445,1225,1031,1133]	8	hSpCas9	negative selection	8315947
203128973	203128996	1	+	27260156	PANC0813	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.6728643692592651	[1191]	[2346,2200,2028,2350]	9	hSpCas9	negative selection	8315948
203129081	203129104	1	-	27260156	PANC0813	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.3413817338277416	[1187]	[1912,1781,1844,1554]	5	hSpCas9	negative selection	8380228
203165889	203165912	1	-	27260156	PANC0813	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-0.15335007880339768	[83]	[75,117,62,95]	-3	hSpCas9	negative selection	8380229
203165744	203165767	1	-	27260156	PANC0813	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.1967339033770394	[581]	[914,696,717,812]	3	hSpCas9	negative selection	8380230
203165577	203165600	1	+	27260156	RDES	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.06266181113487956	[195]	[219,253,186,278]	1	hSpCas9	negative selection	8437197
203165413	203165436	1	-	27260156	RDES	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.5508798295635176	[693]	[1016,1084,1077,1556]	8	hSpCas9	negative selection	8437198
203128973	203128996	1	+	27260156	RDES	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.6139407366660654	[1191]	[1815,1850,2386,2416]	8	hSpCas9	negative selection	8437199
203129081	203129104	1	-	27260156	RDES	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.10383767083861684	[1187]	[1123,1160,1347,1490]	-2	hSpCas9	negative selection	8501479
203165889	203165912	1	-	27260156	RDES	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.5780137536144205	[83]	[118,154,167,133]	8	hSpCas9	negative selection	8501480
203165744	203165767	1	-	27260156	RDES	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.3393509361432547	[581]	[623,1022,779,983]	5	hSpCas9	negative selection	8501481
203165577	203165600	1	+	27260156	PC3	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.6370108378195936	[195]	[264,191,591,260]	9	hSpCas9	negative selection	8558448
203165413	203165436	1	-	27260156	PC3	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.3019182347876225	[693]	[538,992,1299,794]	6	hSpCas9	negative selection	8558449
203128973	203128996	1	+	27260156	PC3	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.38726464672524363	[1191]	[1064,1293,2554,1767]	7	hSpCas9	negative selection	8558450
203129081	203129104	1	-	27260156	PC3	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.04980533302411083	[1187]	[750,852,1982,1401]	-1	hSpCas9	negative selection	8622730
203165889	203165912	1	-	27260156	PC3	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.6853664597184412	[83]	[27,121,213,252]	9	hSpCas9	negative selection	8622731
203165744	203165767	1	-	27260156	PC3	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.21721899619657767	[581]	[395,486,590,544]	-5	hSpCas9	negative selection	8622732
203165577	203165600	1	+	27260156	PATU8988T	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.06874543223095864	[195]	[187,175,195,159]	-1	hSpCas9	negative selection	8679699
203165413	203165436	1	-	27260156	PATU8988T	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.4623857447085338	[693]	[603,1398,899,829]	7	hSpCas9	negative selection	8679700
203128973	203128996	1	+	27260156	PATU8988T	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.6597155228725073	[1191]	[2216,1774,1358,1938]	9	hSpCas9	negative selection	8679701
203129081	203129104	1	-	27260156	PATU8988T	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.24291486425588427	[1187]	[1206,1177,1604,1428]	4	hSpCas9	negative selection	8743981
203165889	203165912	1	-	27260156	PATU8988T	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.3819665806126875	[83]	[217,105,49,44]	6	hSpCas9	negative selection	8743982
203165744	203165767	1	-	27260156	PATU8988T	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.5250317108594821	[581]	[319,354,418,471]	-7	hSpCas9	negative selection	8743983
203165577	203165600	1	+	27260156	T47D	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	-0.018347662697358436	[195]	[225,226,235,211]	0	hSpCas9	negative selection	8800950
203165413	203165436	1	-	27260156	T47D	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.3534665937881316	[693]	[1077,924,1143,990]	7	hSpCas9	negative selection	8800951
203128973	203128996	1	+	27260156	T47D	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.45082456946307015	[1191]	[2193,1529,2026,1870]	8	hSpCas9	negative selection	8800952
203129081	203129104	1	-	27260156	T47D	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.01584466664502182	[1187]	[1367,1237,1534,1341]	0	hSpCas9	negative selection	8865232
203165889	203165912	1	-	27260156	T47D	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.13333887589845084	[83]	[104,62,123,141]	3	hSpCas9	negative selection	8865233
203165744	203165767	1	-	27260156	T47D	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.2148644388579697	[581]	[633,487,624,597]	-5	hSpCas9	negative selection	8865234
203165577	203165600	1	+	27260156	SU8686	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.25274733728719845	[195]	[168,148,253,397]	4	hSpCas9	negative selection	8922201
203165413	203165436	1	-	27260156	SU8686	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.47781877990743116	[693]	[834,825,1220,986]	7	hSpCas9	negative selection	8922202
203128973	203128996	1	+	27260156	SU8686	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.8276431903824877	[1191]	[1796,1822,2154,2781]	9	hSpCas9	negative selection	8922203
203129081	203129104	1	-	27260156	SU8686	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.36602956716332136	[1187]	[1362,1240,1719,1849]	6	hSpCas9	negative selection	8986483
203165889	203165912	1	-	27260156	SU8686	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	-1.1392665402875148	[83]	[40,46,22,37]	-8	hSpCas9	negative selection	8986484
203165744	203165767	1	-	27260156	SU8686	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.10792370478528551	[581]	[456,554,737,790]	1	hSpCas9	negative selection	8986485
203165577	203165600	1	+	27260156	SKES1	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.11695881720856138	[195]	[136,205,207,275]	2	hSpCas9	negative selection	9043452
203165413	203165436	1	-	27260156	SKES1	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.5514688447648097	[693]	[1170,1145,875,906]	9	hSpCas9	negative selection	9043453
203128973	203128996	1	+	27260156	SKES1	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.5408735663647932	[1191]	[1828,1995,1568,1573]	9	hSpCas9	negative selection	9043454
203129081	203129104	1	-	27260156	SKES1	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.1058985848022771	[1187]	[1360,1030,1075,968]	-2	hSpCas9	negative selection	9107734
203165889	203165912	1	-	27260156	SKES1	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.6095623534489656	[83]	[231,112,115,68]	9	hSpCas9	negative selection	9107735
203165744	203165767	1	-	27260156	SKES1	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.3095283911003507	[581]	[559,504,504,331]	-6	hSpCas9	negative selection	9107736
203165577	203165600	1	+	27260156	TOV112D	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.12107464165410953	[195]	[186,300,210,174]	2	hSpCas9	negative selection	9164703
203165413	203165436	1	-	27260156	TOV112D	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.4749018964340266	[693]	[776,1108,1000,993]	8	hSpCas9	negative selection	9164704
203128973	203128996	1	+	27260156	TOV112D	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.4362268724515663	[1191]	[1555,1875,1547,1539]	7	hSpCas9	negative selection	9164705
203129081	203129104	1	-	27260156	TOV112D	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.03676286445094212	[1187]	[1007,1383,1234,1055]	0	hSpCas9	negative selection	9228985
203165889	203165912	1	-	27260156	TOV112D	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.7436887439709827	[83]	[162,185,186,42]	9	hSpCas9	negative selection	9228986
203165744	203165767	1	-	27260156	TOV112D	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.07871237931745198	[581]	[704,685,426,437]	-1	hSpCas9	negative selection	9228987
203165577	203165600	1	+	27260156	TC71	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.13349975586093832	[195]	[222,275,205,216]	3	hSpCas9	negative selection	9285954
203165413	203165436	1	-	27260156	TC71	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.35846261641849353	[693]	[1075,866,910,959]	8	hSpCas9	negative selection	9285955
203128973	203128996	1	+	27260156	TC71	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.39324858055337875	[1191]	[1398,1732,1754,1838]	8	hSpCas9	negative selection	9285956
203129081	203129104	1	-	27260156	TC71	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.0644547155217261	[1187]	[1334,1424,1182,1391]	1	hSpCas9	negative selection	9350236
203165889	203165912	1	-	27260156	TC71	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.06482873427098346	[83]	[79,87,107,100]	1	hSpCas9	negative selection	9350237
203165744	203165767	1	-	27260156	TC71	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	-0.2648526584635991	[581]	[593,567,409,505]	-6	hSpCas9	negative selection	9350238
203165577	203165600	1	+	27260156	TC32	viability	GGCGACCCGCAGAAGTACTATGG	ADORA1	ENSG00000163485	0.030315148246577106	[195]	[260,80,315,133]	0	hSpCas9	negative selection	9407205
203165413	203165436	1	-	27260156	TC32	viability	CTCGAACTCGCACTTGATCACGG	ADORA1	ENSG00000163485	0.28485978365950115	[693]	[832,472,950,1032]	5	hSpCas9	negative selection	9407206
203128973	203128996	1	+	27260156	TC32	viability	CTTCTGCTTCATCGTGTCGCTGG	ADORA1	ENSG00000163485	0.689356944703984	[1191]	[1719,1377,2327,1962]	9	hSpCas9	negative selection	9407207
203129081	203129104	1	-	27260156	TC32	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.44487002666129283	[1187]	[747,607,1172,855]	-7	hSpCas9	negative selection	9471487
203165889	203165912	1	-	27260156	TC32	viability	GAAGGCGGGGTCTAGTCATCAGG	ADORA1	ENSG00000163485	0.7511886522177071	[83]	[134,121,141,128]	9	hSpCas9	negative selection	9471488
203165744	203165767	1	-	27260156	TC32	viability	TGGCCGAGTTGCCGTGCGTGAGG	ADORA1	ENSG00000163485	0.01457837755317376	[581]	[477,440,619,709]	0	hSpCas9	negative selection	9471489
203128897	203128920	1	+	27869803	HPAFII	viability after 27 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	0.9323295135835266	[192]	[119,254,NaN]	7	hSpCas9	negative selection	9531461
203128972	203128995	1	-	27869803	HPAFII	viability after 27 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.8315535666019276	[191]	[129,220,NaN]	6	hSpCas9	negative selection	9531462
203129033	203129056	1	-	27869803	HPAFII	viability after 27 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	1.1736625158770952	[130]	[270,58,NaN]	8	hSpCas9	negative selection	9531463
203129174	203129197	1	-	27869803	HPAFII	viability after 27 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.14538560621649954	[809]	[530,420,NaN]	1	hSpCas9	negative selection	9531464
203165417	203165440	1	+	27869803	HPAFII	viability after 27 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.7258858724399972	[107]	[136,57,NaN]	6	hSpCas9	negative selection	9531465
203165785	203165808	1	-	27869803	HPAFII	viability after 27 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.7012215557070627	[148]	[176,85,NaN]	5	hSpCas9	negative selection	9531466
203128897	203128920	1	+	27869803	HPAFII	viability after 15 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.13660498587560205	[192]	[192,185,NaN]	-2	hSpCas9	negative selection	9613910
203128972	203128995	1	-	27869803	HPAFII	viability after 15 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.603230359378568	[191]	[310,314,NaN]	7	hSpCas9	negative selection	9613911
203129033	203129056	1	-	27869803	HPAFII	viability after 15 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.36235002097512725	[130]	[225,152,NaN]	4	hSpCas9	negative selection	9613912
203129174	203129197	1	-	27869803	HPAFII	viability after 15 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.5412393067741244	[809]	[723,519,NaN]	-5	hSpCas9	negative selection	9613913
203165417	203165440	1	+	27869803	HPAFII	viability after 15 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.9639764398654859	[107]	[403,115,NaN]	9	hSpCas9	negative selection	9613914
203165785	203165808	1	-	27869803	HPAFII	viability after 15 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.4590856015294793	[148]	[385,116,NaN]	5	hSpCas9	negative selection	9613915
203128897	203128920	1	+	27869803	ASPC1	viability after 36 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	-0.4540875066408715	[422]	[192,123,33]	-4	hSpCas9	negative selection	9696359
203128972	203128995	1	-	27869803	ASPC1	viability after 36 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.9840217769083621	[438]	[31,626,232]	8	hSpCas9	negative selection	9696360
203129033	203129056	1	-	27869803	ASPC1	viability after 36 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	1.0590482177163967	[453]	[720,146,197]	8	hSpCas9	negative selection	9696361
203129174	203129197	1	-	27869803	ASPC1	viability after 36 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.6351544676647063	[1657]	[1507,636,669]	6	hSpCas9	negative selection	9696362
203165417	203165440	1	+	27869803	ASPC1	viability after 36 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	0.0289057362875329	[311]	[128,30,160]	0	hSpCas9	negative selection	9696363
203165785	203165808	1	-	27869803	ASPC1	viability after 36 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.013836649469301188	[383]	[95,203,106]	0	hSpCas9	negative selection	9696364
203128897	203128920	1	+	27869803	PATU8988S	viability after 35 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	0.9513530652687967	[380]	[392,199,NaN]	8	hSpCas9	negative selection	9778808
203128972	203128995	1	-	27869803	PATU8988S	viability after 35 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.2520451696468397	[339]	[195,129,NaN]	3	hSpCas9	negative selection	9778809
203129033	203129056	1	-	27869803	PATU8988S	viability after 35 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.04829774198125236	[345]	[185,101,NaN]	0	hSpCas9	negative selection	9778810
203129174	203129197	1	-	27869803	PATU8988S	viability after 35 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.5013327106546268	[1391]	[828,757,NaN]	5	hSpCas9	negative selection	9778811
203165417	203165440	1	+	27869803	PATU8988S	viability after 35 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	-0.19334141361837132	[276]	[127,66,NaN]	-2	hSpCas9	negative selection	9778812
203165785	203165808	1	-	27869803	PATU8988S	viability after 35 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.17023657866628825	[409]	[320,49,NaN]	2	hSpCas9	negative selection	9778813
203128897	203128920	1	+	27869803	PATU8988S	viability after 31 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	0.5106276208308539	[380]	[204,230,NaN]	6	hSpCas9	negative selection	9861257
203128972	203128995	1	-	27869803	PATU8988S	viability after 31 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.6232609559116397	[339]	[159,270,NaN]	7	hSpCas9	negative selection	9861258
203129033	203129056	1	-	27869803	PATU8988S	viability after 31 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	0.15232384274467226	[345]	[195,98,NaN]	2	hSpCas9	negative selection	9861259
203129174	203129197	1	-	27869803	PATU8988S	viability after 31 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.675952502794237	[1391]	[778,1023,NaN]	7	hSpCas9	negative selection	9861260
203165417	203165440	1	+	27869803	PATU8988S	viability after 31 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	-1.185441032799113	[276]	[70,19,NaN]	-8	hSpCas9	negative selection	9861261
203165785	203165808	1	-	27869803	PATU8988S	viability after 31 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	-0.1710296518823909	[409]	[186,91,NaN]	-2	hSpCas9	negative selection	9861262
203128897	203128920	1	+	27869803	HPAFII	viability after 35 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	1.4306304717999265	[192]	[78,470,NaN]	8	hSpCas9	negative selection	9943706
203128972	203128995	1	-	27869803	HPAFII	viability after 35 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	1.1437266695235888	[191]	[91,352,NaN]	7	hSpCas9	negative selection	9943707
203129033	203129056	1	-	27869803	HPAFII	viability after 35 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	1.1145854323673996	[130]	[168,114,NaN]	7	hSpCas9	negative selection	9943708
203129174	203129197	1	-	27869803	HPAFII	viability after 35 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	0.11865097779351319	[809]	[511,369,NaN]	0	hSpCas9	negative selection	9943709
203165417	203165440	1	+	27869803	HPAFII	viability after 35 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	1.086950656870554	[107]	[165,59,NaN]	7	hSpCas9	negative selection	9943710
203165785	203165808	1	-	27869803	HPAFII	viability after 35 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.9369575322185575	[148]	[142,145,NaN]	6	hSpCas9	negative selection	9943711
203128897	203128920	1	+	27869803	HPAFII	viability after 31 days	TCGCCCTGGTCTCTGTGCCCGGG	ADORA1	ENSG00000163485	0.9253121460447489	[192]	[131,285,NaN]	7	hSpCas9	negative selection	10026155
203128972	203128995	1	-	27869803	HPAFII	viability after 31 days	CAGCGACACGATGAAGCAGAAGG	ADORA1	ENSG00000163485	0.8502855834819423	[191]	[121,272,NaN]	6	hSpCas9	negative selection	10026156
203129033	203129056	1	-	27869803	HPAFII	viability after 31 days	CAATGTTGATGAGGATGGCGAGG	ADORA1	ENSG00000163485	1.3050792087651462	[130]	[229,128,NaN]	8	hSpCas9	negative selection	10026157
203129174	203129197	1	-	27869803	HPAFII	viability after 31 days	CGCTGTGGACTCACCGGAGAGGG	ADORA1	ENSG00000163485	-0.2570334621235282	[809]	[433,321,NaN]	-2	hSpCas9	negative selection	10026158
203165417	203165440	1	+	27869803	HPAFII	viability after 31 days	GATCAAGTGCGAGTTCGAGAAGG	ADORA1	ENSG00000163485	1.4676079572381877	[107]	[203,127,NaN]	9	hSpCas9	negative selection	10026159
203165785	203165808	1	-	27869803	HPAFII	viability after 31 days	GCGGAACTTCTGGATGCGGAAGG	ADORA1	ENSG00000163485	0.8971586991751002	[148]	[160,149,NaN]	6	hSpCas9	negative selection	10026160
203129032	203129055	1	-	28162770	P31FUJ	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.9114402730019219	[232]	[514]	9	hSpCas9	negative selection	10107608
203129092	203129115	1	-	28162770	P31FUJ	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	0.44902183555936626	[47]	[76]	5	hSpCas9	negative selection	10107609
203129159	203129182	1	-	28162770	P31FUJ	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.006868208353904892	[165]	[195]	0	hSpCas9	negative selection	10107610
203128849	203128872	1	-	28162770	P31FUJ	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.8632793643879033	[482]	[311]	-6	hSpCas9	negative selection	10107611
203128942	203128965	1	+	28162770	P31FUJ	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	-0.40025895026594127	[72]	[64]	-4	hSpCas9	negative selection	10107612
203128969	203128992	1	-	28162770	P31FUJ	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.023345815834175387	[174]	[208]	0	hSpCas9	negative selection	10107613
203129011	203129034	1	-	28162770	P31FUJ	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-1.5864391590290792	[45]	[17]	-7	hSpCas9	negative selection	10107614
203129081	203129104	1	-	28162770	P31FUJ	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.2811771445581015	[242]	[346]	3	hSpCas9	negative selection	10107615
203128919	203128942	1	+	28162770	P31FUJ	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.6232492798720292	[257]	[466]	7	hSpCas9	negative selection	10107616
203128995	203129018	1	+	28162770	P31FUJ	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.7645036864163582	[267]	[534]	8	hSpCas9	negative selection	10107617
203129032	203129055	1	-	28162770	TF1	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	NaN	[NaN]	[480]	1	hSpCas9	negative selection	10276974
203129092	203129115	1	-	28162770	TF1	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10276975
203129159	203129182	1	-	28162770	TF1	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	NaN	[NaN]	[255]	1	hSpCas9	negative selection	10276976
203128849	203128872	1	-	28162770	TF1	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	NaN	[NaN]	[148]	1	hSpCas9	negative selection	10276977
203128942	203128965	1	+	28162770	TF1	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10276978
203128969	203128992	1	-	28162770	TF1	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10276979
203129011	203129034	1	-	28162770	TF1	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10276980
203129081	203129104	1	-	28162770	TF1	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	NaN	[NaN]	[212]	1	hSpCas9	negative selection	10276981
203128919	203128942	1	+	28162770	TF1	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	NaN	[NaN]	[209]	1	hSpCas9	negative selection	10276982
203128995	203129018	1	+	28162770	TF1	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	NaN	[NaN]	[292]	1	hSpCas9	negative selection	10276983
203129032	203129055	1	-	28162770	SKM1	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.4590184532851508	[92]	[225]	4	hSpCas9	negative selection	10446340
203129092	203129115	1	-	28162770	SKM1	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-4.281433316659303	[21]	[1]	-9	hSpCas9	negative selection	10446341
203129159	203129182	1	-	28162770	SKM1	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.3051102198813336	[37]	[82]	3	hSpCas9	negative selection	10446342
203128849	203128872	1	-	28162770	SKM1	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.5532985421015196	[126]	[152]	-4	hSpCas9	negative selection	10446343
203128942	203128965	1	+	28162770	SKM1	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	0.8517700696570067	[20]	[66]	7	hSpCas9	negative selection	10446344
203128969	203128992	1	-	28162770	SKM1	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	-0.23703919730084932	[41]	[62]	-2	hSpCas9	negative selection	10446345
203129011	203129034	1	-	28162770	SKM1	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-3.8220016980220053	[7]	[0]	-9	hSpCas9	negative selection	10446346
203129081	203129104	1	-	28162770	SKM1	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.044394119358453416	[48]	[83]	0	hSpCas9	negative selection	10446347
203128919	203128942	1	+	28162770	SKM1	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.7725468515283487	[49]	[150]	7	hSpCas9	negative selection	10446348
203128995	203129018	1	+	28162770	SKM1	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.8952680948032808	[58]	[193]	8	hSpCas9	negative selection	10446349
203129032	203129055	1	-	28162770	SKM1	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.4590184532851508	[92]	[225]	4	hSpCas9	negative selection	10615706
203129092	203129115	1	-	28162770	SKM1	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-4.281433316659303	[21]	[1]	-9	hSpCas9	negative selection	10615707
203129159	203129182	1	-	28162770	SKM1	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.3051102198813336	[37]	[82]	3	hSpCas9	negative selection	10615708
203128849	203128872	1	-	28162770	SKM1	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.5532985421015196	[126]	[152]	-4	hSpCas9	negative selection	10615709
203128942	203128965	1	+	28162770	SKM1	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	0.8517700696570067	[20]	[66]	7	hSpCas9	negative selection	10615710
203128969	203128992	1	-	28162770	SKM1	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	-0.23703919730084932	[41]	[62]	-2	hSpCas9	negative selection	10615711
203129011	203129034	1	-	28162770	SKM1	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-3.8220016980220053	[7]	[0]	-9	hSpCas9	negative selection	10615712
203129081	203129104	1	-	28162770	SKM1	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.044394119358453416	[48]	[83]	0	hSpCas9	negative selection	10615713
203128919	203128942	1	+	28162770	SKM1	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.7725468515283487	[49]	[150]	7	hSpCas9	negative selection	10615714
203128995	203129018	1	+	28162770	SKM1	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.8952680948032808	[58]	[193]	8	hSpCas9	negative selection	10615715
203129032	203129055	1	-	28162770	PL21	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	-0.04404873044847235	[288]	[121]	0	hSpCas9	negative selection	10785072
203129092	203129115	1	-	28162770	PL21	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	1.3221301388679305	[33]	[36]	9	hSpCas9	negative selection	10785073
203129159	203129182	1	-	28162770	PL21	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	-1.0082595347676282	[170]	[36]	-6	hSpCas9	negative selection	10785074
203128849	203128872	1	-	28162770	PL21	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	0.06462464383283928	[434]	[197]	0	hSpCas9	negative selection	10785075
203128942	203128965	1	+	28162770	PL21	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	-0.7592184010133343	[69]	[17]	-5	hSpCas9	negative selection	10785076
203128969	203128992	1	-	28162770	PL21	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.22109923312496632	[204]	[103]	2	hSpCas9	negative selection	10785077
203129011	203129034	1	-	28162770	PL21	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	2.0481365210442704	[24]	[44]	9	hSpCas9	negative selection	10785078
203129081	203129104	1	-	28162770	PL21	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.7003247119597654	[167]	[44]	-5	hSpCas9	negative selection	10785079
203128919	203128942	1	+	28162770	PL21	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.1093741505661377	[163]	[76]	1	hSpCas9	negative selection	10785080
203128995	203129018	1	+	28162770	PL21	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.667104905812025	[190]	[131]	6	hSpCas9	negative selection	10785081
203129032	203129055	1	-	28162770	P31FUJ	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.9114402730019219	[232]	[514]	9	hSpCas9	negative selection	10954438
203129092	203129115	1	-	28162770	P31FUJ	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	0.44902183555936626	[47]	[76]	5	hSpCas9	negative selection	10954439
203129159	203129182	1	-	28162770	P31FUJ	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.006868208353904892	[165]	[195]	0	hSpCas9	negative selection	10954440
203128849	203128872	1	-	28162770	P31FUJ	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.8632793643879033	[482]	[311]	-6	hSpCas9	negative selection	10954441
203128942	203128965	1	+	28162770	P31FUJ	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	-0.40025895026594127	[72]	[64]	-4	hSpCas9	negative selection	10954442
203128969	203128992	1	-	28162770	P31FUJ	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.023345815834175387	[174]	[208]	0	hSpCas9	negative selection	10954443
203129011	203129034	1	-	28162770	P31FUJ	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-1.5864391590290792	[45]	[17]	-7	hSpCas9	negative selection	10954444
203129081	203129104	1	-	28162770	P31FUJ	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.2811771445581015	[242]	[346]	3	hSpCas9	negative selection	10954445
203128919	203128942	1	+	28162770	P31FUJ	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.6232492798720292	[257]	[466]	7	hSpCas9	negative selection	10954446
203128995	203129018	1	+	28162770	P31FUJ	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.7645036864163582	[267]	[534]	8	hSpCas9	negative selection	10954447
203129032	203129055	1	-	28162770	OCIAML5	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.609513514351877	[182]	[503]	5	hSpCas9	negative selection	11123804
203129092	203129115	1	-	28162770	OCIAML5	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-1.5234438234026262	[42]	[26]	-7	hSpCas9	negative selection	11123805
203129159	203129182	1	-	28162770	OCIAML5	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	1.228306845600023	[47]	[202]	9	hSpCas9	negative selection	11123806
203128849	203128872	1	-	28162770	OCIAML5	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.8259537305448656	[218]	[222]	-5	hSpCas9	negative selection	11123807
203128942	203128965	1	+	28162770	OCIAML5	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	0.037750511385580054	[33]	[62]	0	hSpCas9	negative selection	11123808
203128969	203128992	1	-	28162770	OCIAML5	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.29119048011623516	[90]	[200]	2	hSpCas9	negative selection	11123809
203129011	203129034	1	-	28162770	OCIAML5	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-0.8520665708639972	[10]	[10]	-5	hSpCas9	negative selection	11123810
203129081	203129104	1	-	28162770	OCIAML5	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.022402547052144145	[137]	[252]	0	hSpCas9	negative selection	11123811
203128919	203128942	1	+	28162770	OCIAML5	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.2746905714219417	[146]	[320]	2	hSpCas9	negative selection	11123812
203128995	203129018	1	+	28162770	OCIAML5	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.23379416578984072	[105]	[224]	2	hSpCas9	negative selection	11123813
203129032	203129055	1	-	28162770	EOL1	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.5787247670229791	[623]	[490]	5	hSpCas9	negative selection	11293170
203129092	203129115	1	-	28162770	EOL1	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	1.4002812025369322	[63]	[88]	9	hSpCas9	negative selection	11293171
203129159	203129182	1	-	28162770	EOL1	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.7692695460926237	[293]	[263]	6	hSpCas9	negative selection	11293172
203128849	203128872	1	-	28162770	EOL1	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.6565469117109084	[744]	[248]	-5	hSpCas9	negative selection	11293173
203128942	203128965	1	+	28162770	EOL1	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	-0.8597235373740282	[123]	[35]	-5	hSpCas9	negative selection	11293174
203128969	203128992	1	-	28162770	EOL1	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.7721216624236154	[378]	[340]	6	hSpCas9	negative selection	11293175
203129011	203129034	1	-	28162770	EOL1	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-1.453963851683195	[25]	[4]	-7	hSpCas9	negative selection	11293176
203129081	203129104	1	-	28162770	EOL1	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.5585528952282095	[240]	[186]	5	hSpCas9	negative selection	11293177
203128919	203128942	1	+	28162770	EOL1	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.7044219572060317	[211]	[181]	6	hSpCas9	negative selection	11293178
203128995	203129018	1	+	28162770	EOL1	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.07537267381830348	[244]	[135]	0	hSpCas9	negative selection	11293179
203129032	203129055	1	-	28162770	MOLM13	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	1.125885509892557	[397]	[627]	8	hSpCas9	negative selection	11462536
203129092	203129115	1	-	28162770	MOLM13	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-2.74934133467609	[92]	[9]	-8	hSpCas9	negative selection	11462537
203129159	203129182	1	-	28162770	MOLM13	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.9650759221772942	[191]	[270]	7	hSpCas9	negative selection	11462538
203128849	203128872	1	-	28162770	MOLM13	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.48495952508452056	[601]	[310]	-3	hSpCas9	negative selection	11462539
203128942	203128965	1	+	28162770	MOLM13	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	0.4678893815445788	[93]	[93]	3	hSpCas9	negative selection	11462540
203128969	203128992	1	-	28162770	MOLM13	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	1.1036761413434175	[250]	[389]	8	hSpCas9	negative selection	11462541
203129011	203129034	1	-	28162770	MOLM13	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-0.676500527790596	[41]	[18]	-4	hSpCas9	negative selection	11462542
203129081	203129104	1	-	28162770	MOLM13	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.7096488040076088	[284]	[125]	-4	hSpCas9	negative selection	11462543
203128919	203128942	1	+	28162770	MOLM13	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.5447829810847309	[273]	[288]	4	hSpCas9	negative selection	11462544
203128995	203129018	1	+	28162770	MOLM13	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	-0.012103559575034756	[264]	[189]	0	hSpCas9	negative selection	11462545
203129032	203129055	1	-	28162770	HEL	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.9336742138982912	[366]	[448]	7	hSpCas9	negative selection	11631902
203129092	203129115	1	-	28162770	HEL	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	0.15293356431954108	[65]	[46]	1	hSpCas9	negative selection	11631903
203129159	203129182	1	-	28162770	HEL	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.6499704012314327	[198]	[199]	5	hSpCas9	negative selection	11631904
203128849	203128872	1	-	28162770	HEL	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-1.2069868884713442	[500]	[138]	-6	hSpCas9	negative selection	11631905
203128942	203128965	1	+	28162770	HEL	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	1.485637870915628	[62]	[112]	9	hSpCas9	negative selection	11631906
203128969	203128992	1	-	28162770	HEL	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.21592416494515962	[245]	[182]	1	hSpCas9	negative selection	11631907
203129011	203129034	1	-	28162770	HEL	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-1.472738385419579	[25]	[5]	-7	hSpCas9	negative selection	11631908
203129081	203129104	1	-	28162770	HEL	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	1.372850755125501	[210]	[349]	9	hSpCas9	negative selection	11631909
203128919	203128942	1	+	28162770	HEL	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.457325323289037	[198]	[174]	4	hSpCas9	negative selection	11631910
203128995	203129018	1	+	28162770	HEL	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	-0.021774967817558943	[232]	[146]	0	hSpCas9	negative selection	11631911
203129032	203129055	1	-	28162770	MV411	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.22775518492107527	[368]	[363]	2	hSpCas9	negative selection	11801268
203129092	203129115	1	-	28162770	MV411	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	0.9460568332994989	[60]	[98]	8	hSpCas9	negative selection	11801269
203129159	203129182	1	-	28162770	MV411	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	-0.7205012399849262	[177]	[90]	-5	hSpCas9	negative selection	11801270
203128849	203128872	1	-	28162770	MV411	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.8437103372754203	[391]	[183]	-5	hSpCas9	negative selection	11801271
203128942	203128965	1	+	28162770	MV411	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	-1.2182260215660365	[57]	[20]	-7	hSpCas9	negative selection	11801272
203128969	203128992	1	-	28162770	MV411	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.7505482975156441	[138]	[196]	6	hSpCas9	negative selection	11801273
203129011	203129034	1	-	28162770	MV411	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-0.28307716591600407	[25]	[17]	-2	hSpCas9	negative selection	11801274
203129081	203129104	1	-	28162770	MV411	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.930375211067229	[184]	[296]	8	hSpCas9	negative selection	11801275
203128919	203128942	1	+	28162770	MV411	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.8518175053311723	[122]	[186]	7	hSpCas9	negative selection	11801276
203128995	203129018	1	+	28162770	MV411	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.42183325627031365	[178]	[201]	4	hSpCas9	negative selection	11801277
203129032	203129055	1	-	28162770	MONOMAC1	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.6917732939236083	[181]	[336]	6	hSpCas9	negative selection	11970634
203129092	203129115	1	-	28162770	MONOMAC1	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-1.670968035391966	[24]	[8]	-8	hSpCas9	negative selection	11970635
203129159	203129182	1	-	28162770	MONOMAC1	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	-0.17237479282528462	[115]	[117]	-1	hSpCas9	negative selection	11970636
203128849	203128872	1	-	28162770	MONOMAC1	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.675610003188733	[293]	[210]	-5	hSpCas9	negative selection	11970637
203128942	203128965	1	+	28162770	MONOMAC1	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	0.3879256536616025	[43]	[65]	4	hSpCas9	negative selection	11970638
203128969	203128992	1	-	28162770	MONOMAC1	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	0.16429963238604411	[129]	[166]	1	hSpCas9	negative selection	11970639
203129011	203129034	1	-	28162770	MONOMAC1	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	3.376954535840599	[21]	[261]	9	hSpCas9	negative selection	11970640
203129081	203129104	1	-	28162770	MONOMAC1	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	-0.46007125289334755	[155]	[129]	-4	hSpCas9	negative selection	11970641
203128919	203128942	1	+	28162770	MONOMAC1	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.6729026123760733	[115]	[211]	6	hSpCas9	negative selection	11970642
203128995	203129018	1	+	28162770	MONOMAC1	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	0.4749089552562424	[117]	[187]	5	hSpCas9	negative selection	11970643
203129032	203129055	1	-	28162770	OCIAML2	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.5833650643985682	[58]	[489]	5	hSpCas9	negative selection	12140000
203129092	203129115	1	-	28162770	OCIAML2	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-0.1778480760143153	[9]	[48]	-1	hSpCas9	negative selection	12140001
203129159	203129182	1	-	28162770	OCIAML2	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	-0.49977617090167775	[24]	[97]	-4	hSpCas9	negative selection	12140002
203128849	203128872	1	-	28162770	OCIAML2	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.9351360007853049	[88]	[257]	-6	hSpCas9	negative selection	12140003
203128942	203128965	1	+	28162770	OCIAML2	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	0.44993570726343357	[13]	[105]	4	hSpCas9	negative selection	12140004
203128969	203128992	1	-	28162770	OCIAML2	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	-1.1710695433832534	[38]	[95]	-6	hSpCas9	negative selection	12140005
203129011	203129034	1	-	28162770	OCIAML2	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-3.4706298252421615	[7]	[3]	-9	hSpCas9	negative selection	12140006
203129081	203129104	1	-	28162770	OCIAML2	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.5479061261952662	[28]	[234]	5	hSpCas9	negative selection	12140007
203128919	203128942	1	+	28162770	OCIAML2	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	-0.458246100786329	[28]	[116]	-4	hSpCas9	negative selection	12140008
203128995	203129018	1	+	28162770	OCIAML2	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	-0.861214280796466	[38]	[118]	-6	hSpCas9	negative selection	12140009
203129032	203129055	1	-	28162770	OCIAML3	viability	AATGTTGATGAGGATGGCGAGGG	ADORA1	ENSG00000163485	0.40043283433393617	[64]	[258]	4	hSpCas9	negative selection	12309366
203129092	203129115	1	-	28162770	OCIAML3	viability	GGTGAGGATGAGGACCGGACAGG	ADORA1	ENSG00000163485	-0.05343925896146029	[10]	[31]	0	hSpCas9	negative selection	12309367
203129159	203129182	1	-	28162770	OCIAML3	viability	GGAGAGGGATCTTGACCCGGAGG	ADORA1	ENSG00000163485	0.02337633808937037	[43]	[134]	0	hSpCas9	negative selection	12309368
203128849	203128872	1	-	28162770	OCIAML3	viability	GGCCTGGAAAGCTGAGATGGAGG	ADORA1	ENSG00000163485	-0.936113617149156	[134]	[212]	-6	hSpCas9	negative selection	12309369
203128942	203128965	1	+	28162770	OCIAML3	viability	TGAAGGTGAACCAGGCGCTGCGG	ADORA1	ENSG00000163485	0.7716418319925171	[12]	[66]	7	hSpCas9	negative selection	12309370
203128969	203128992	1	-	28162770	OCIAML3	viability	CGACACGATGAAGCAGAAGGTGG	ADORA1	ENSG00000163485	-0.4409283103197739	[66]	[148]	-3	hSpCas9	negative selection	12309371
203129011	203129034	1	-	28162770	OCIAML3	viability	GGGGATGACCAGGGCACCCACGG	ADORA1	ENSG00000163485	-2.7639326417664756	[8]	[3]	-9	hSpCas9	negative selection	12309372
203129081	203129104	1	-	28162770	OCIAML3	viability	GGACCGGACAGGCAACCATGAGG	ADORA1	ENSG00000163485	0.03326566525495743	[55]	[172]	0	hSpCas9	negative selection	12309373
203128919	203128942	1	+	28162770	OCIAML3	viability	GAACGTGCTGGTGATCTGGGCGG	ADORA1	ENSG00000163485	0.932538174171671	[41]	[241]	7	hSpCas9	negative selection	12309374
203128995	203129018	1	+	28162770	OCIAML3	viability	GCGGTGGCTGATGTGGCCGTGGG	ADORA1	ENSG00000163485	-0.2238960119268357	[52]	[136]	-2	hSpCas9	negative selection	12309375