Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:135
• Symbol:ADORA2A
• Description:adenosine A2a receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/ADORA2A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
24427454	24427477	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GACAAGGGAGTGTTTCTAGATGG	ADORA2A	ENSG00000128271	-0.04226150269995721	[54,74]	[9,17]	0	dCas9-VP64	positive selection	2384578
24427387	24427410	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGCTTGAAGGGGCAGTGCTGG	ADORA2A	ENSG00000128271	2.950322938808523	[72,6]	[48,87]	8	dCas9-VP64	positive selection	2384579
24427362	24427385	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGGCCTCACAATGCCCCAGG	ADORA2A	ENSG00000128271	0.6051237310130071	[58,70]	[22,19]	2	dCas9-VP64	positive selection	2384580
24423504	24423527	22	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGGTCTTTCGCCCAGGCTGG	ADORA2A	ENSG00000128271	-2.209136716937512	[53,42]	[1,0]	-9	dCas9-VP64	positive selection	2420421
24427454	24427477	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GACAAGGGAGTGTTTCTAGATGG	ADORA2A	ENSG00000128271	-1.0353878823879792	[129,43]	[17,8]	-8	dCas9-VP64	positive selection	2479833
24427387	24427410	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGCTTGAAGGGGCAGTGCTGG	ADORA2A	ENSG00000128271	-0.08706788930516546	[86,76]	[32,16]	0	dCas9-VP64	positive selection	2479834
24427362	24427385	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGGCCTCACAATGCCCCAGG	ADORA2A	ENSG00000128271	0.6456234235366072	[87,140]	[32,81]	5	dCas9-VP64	positive selection	2479835
24423504	24423527	22	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGGTCTTTCGCCCAGGCTGG	ADORA2A	ENSG00000128271	1.702624122254095	[35,28]	[62,7]	8	dCas9-VP64	positive selection	2515676
24423899	24423922	22	+	27661255	K562	viability	GGCCGGAGCCGGAGACCCAGCGG	ADORA2A	ENSG00000128271	-0.04998285780634132	[1055,1093]	[964,712]	-2	dCas9-KRAB	negative selection	5461148
24423958	24423981	22	+	27661255	K562	viability	GTCAGCCGGGGTGCTAGGTCTGG	ADORA2A	ENSG00000128271	0.010433990072466037	[804,1042]	[881,618]	0	dCas9-KRAB	negative selection	5461149
24424292	24424315	22	+	27661255	K562	viability	GCGGGGAGGGAAGGCAAGTGCGG	ADORA2A	ENSG00000128271	-0.03179697147774169	[662,600]	[518,473]	-1	dCas9-KRAB	negative selection	5461150
24423963	24423986	22	-	27661255	K562	viability	GCACGCCAGACCTAGCACCCCGG	ADORA2A	ENSG00000128271	0.1385814265659746	[626,481]	[504,476]	5	dCas9-KRAB	negative selection	5461151
24424103	24424126	22	-	27661255	K562	viability	GGCGGGAAAGGAACCCTGAGGGG	ADORA2A	ENSG00000128271	0.317094019113203	[276,255]	[304,231]	8	dCas9-KRAB	negative selection	5461152