Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:136
• Symbol:ADORA2B
• Description:adenosine A2b receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/ADORA2B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
15945301	15945324	17	-	26472758	Jiyoye	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.31737871115522764	[231]	[217]	2	hSpCas9	negative selection	3353
15945293	15945316	17	+	26472758	Jiyoye	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	1.4851778935071465	[35]	[75]	8	hSpCas9	negative selection	3354
15945439	15945462	17	-	26472758	Jiyoye	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.17386167379207929	[220]	[187]	1	hSpCas9	negative selection	3355
15945337	15945360	17	-	26472758	Jiyoye	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.2854968249176212	[135]	[124]	2	hSpCas9	negative selection	3356
15945403	15945426	17	-	26472758	Jiyoye	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	-0.31661482391259954	[108]	[65]	-2	hSpCas9	negative selection	3357
15945560	15945583	17	-	26472758	Jiyoye	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.6763620143212624	[116]	[140]	5	hSpCas9	negative selection	3358
15945266	15945289	17	+	26472758	Jiyoye	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	3.6872833006986085	[6]	[67]	9	hSpCas9	negative selection	3359
15945320	15945343	17	+	26472758	Jiyoye	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.38164028939873584	[56]	[55]	3	hSpCas9	negative selection	3360
15945370	15945393	17	-	26472758	Jiyoye	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	-0.0995200624180197	[286]	[201]	0	hSpCas9	negative selection	3361
15945488	15945511	17	-	26472758	Jiyoye	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.6060794499199514	[114]	[131]	4	hSpCas9	negative selection	3362
15945301	15945324	17	-	26472758	KBM7	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.12679428026052308	[730,635]	[517,199]	1	hSpCas9	negative selection	194471
15945293	15945316	17	+	26472758	KBM7	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	-0.4024497075117983	[254,168]	[88,60]	-4	hSpCas9	negative selection	194472
15945439	15945462	17	-	26472758	KBM7	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.7926113426450591	[1058,809]	[915,609]	8	hSpCas9	negative selection	194473
15945337	15945360	17	-	26472758	KBM7	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.580446392021578	[610,481]	[334,422]	6	hSpCas9	negative selection	194474
15945403	15945426	17	-	26472758	KBM7	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	1.3889052027572373	[361,263]	[548,230]	9	hSpCas9	negative selection	194475
15945560	15945583	17	-	26472758	KBM7	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.5199941741698663	[557,368]	[448,180]	5	hSpCas9	negative selection	194476
15945266	15945289	17	+	26472758	KBM7	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	0.04759547748739923	[148,186]	[54,107]	0	hSpCas9	negative selection	194477
15945320	15945343	17	+	26472758	KBM7	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.9975724746126409	[366,247]	[182,374]	9	hSpCas9	negative selection	194478
15945370	15945393	17	-	26472758	KBM7	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	-0.20218878756917857	[1169,1126]	[474,466]	-2	hSpCas9	negative selection	194479
15945488	15945511	17	-	26472758	KBM7	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.8616147924164679	[549,492]	[355,524]	8	hSpCas9	negative selection	194480
15945301	15945324	17	-	26472758	Raji	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.3310555089366197	[321]	[93]	3	hSpCas9	negative selection	385589
15945293	15945316	17	+	26472758	Raji	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	-0.5206476872394424	[135]	[21]	-4	hSpCas9	negative selection	385590
15945439	15945462	17	-	26472758	Raji	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.31643152432706523	[480]	[138]	3	hSpCas9	negative selection	385591
15945337	15945360	17	-	26472758	Raji	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	-0.010900482622110075	[342]	[78]	0	hSpCas9	negative selection	385592
15945403	15945426	17	-	26472758	Raji	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	-0.004124779843390991	[120]	[27]	0	hSpCas9	negative selection	385593
15945560	15945583	17	-	26472758	Raji	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.4669259220607398	[211]	[67]	4	hSpCas9	negative selection	385594
15945266	15945289	17	+	26472758	Raji	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	0.23291441745745844	[65]	[17]	2	hSpCas9	negative selection	385595
15945320	15945343	17	+	26472758	Raji	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	-0.2645852420133585	[175]	[33]	-2	hSpCas9	negative selection	385596
15945370	15945393	17	-	26472758	Raji	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.5555878985876428	[515]	[175]	5	hSpCas9	negative selection	385597
15945488	15945511	17	-	26472758	Raji	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	-0.29546455489733037	[274]	[51]	-2	hSpCas9	negative selection	385598
15945301	15945324	17	-	26472758	K562	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	1.4136247183583228	[445]	[1002]	9	hSpCas9	negative selection	576707
15945293	15945316	17	+	26472758	K562	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	1.2245191702287421	[218]	[431]	9	hSpCas9	negative selection	576708
15945439	15945462	17	-	26472758	K562	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.9925170641672765	[851]	[1430]	8	hSpCas9	negative selection	576709
15945337	15945360	17	-	26472758	K562	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.288688994593963	[352]	[363]	2	hSpCas9	negative selection	576710
15945403	15945426	17	-	26472758	K562	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	0.9159968706935843	[166]	[265]	7	hSpCas9	negative selection	576711
15945560	15945583	17	-	26472758	K562	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	1.0428954983775982	[325]	[566]	8	hSpCas9	negative selection	576712
15945266	15945289	17	+	26472758	K562	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	-1.1451480840962787	[130]	[49]	-6	hSpCas9	negative selection	576713
15945320	15945343	17	+	26472758	K562	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.8758796904874947	[172]	[267]	7	hSpCas9	negative selection	576714
15945370	15945393	17	-	26472758	K562	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.3459567541285089	[959]	[1029]	2	hSpCas9	negative selection	576715
15945488	15945511	17	-	26472758	K562	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.045485279153987784	[426]	[371]	0	hSpCas9	negative selection	576716
15945482	15945505	17	-	26627737	DLD1	viability	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.05442141616869667	[1049]	[405,343,214]	0	hSpCas9	negative selection	796227
15945524	15945547	17	+	26627737	DLD1	viability	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.7667060276880594	[454]	[307,161,250]	7	hSpCas9	negative selection	796228
15974736	15974759	17	-	26627737	DLD1	viability	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	0.9498723696982652	[363]	[202,311,157]	8	hSpCas9	negative selection	796234
15974741	15974764	17	-	26627737	DLD1	viability	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.2563534427470149	[685]	[174,231,139]	-3	hSpCas9	negative selection	796235
15975021	15975044	17	-	26627737	DLD1	viability	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-0.4187710050874274	[757]	[249,69,202]	-4	hSpCas9	negative selection	796236
15975074	15975097	17	-	26627737	DLD1	viability	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.007361807998726322	[725]	[253,182,242]	0	hSpCas9	negative selection	796237
15945482	15945505	17	-	26627737	GBM cells	viability after 5 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	0.035664884470481883	[522]	[294,279]	0	hSpCas9	negative selection	878542
15945524	15945547	17	+	26627737	GBM cells	viability after 5 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.2557945686074725	[366]	[225,243]	4	hSpCas9	negative selection	878543
15974736	15974759	17	-	26627737	GBM cells	viability after 5 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	0.4972259292658613	[250]	[213,165]	7	hSpCas9	negative selection	878549
15974741	15974764	17	-	26627737	GBM cells	viability after 5 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.33025318649363006	[263]	[151,203]	5	hSpCas9	negative selection	878550
15975021	15975044	17	-	26627737	GBM cells	viability after 5 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	0.1382521882761231	[265]	[124,188]	2	hSpCas9	negative selection	878551
15975074	15975097	17	-	26627737	GBM cells	viability after 5 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.33501298969235904	[390]	[255,272]	5	hSpCas9	negative selection	878552
15945482	15945505	17	-	26627737	GBM cells	viability after 13 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	0.005360510080103298	[522]	[275,291]	0	hSpCas9	negative selection	960857
15945524	15945547	17	+	26627737	GBM cells	viability after 13 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.5512738603971663	[366]	[293,289]	7	hSpCas9	negative selection	960858
15974736	15974759	17	-	26627737	GBM cells	viability after 13 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	0.896485196919689	[250]	[322,196]	9	hSpCas9	negative selection	960864
15974741	15974764	17	-	26627737	GBM cells	viability after 13 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.304475255273609	[263]	[177,175]	4	hSpCas9	negative selection	960865
15975021	15975044	17	-	26627737	GBM cells	viability after 13 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-0.13369574594755476	[265]	[130,131]	-2	hSpCas9	negative selection	960866
15975074	15975097	17	-	26627737	GBM cells	viability after 13 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.5800195806426184	[390]	[379,265]	7	hSpCas9	negative selection	960867
15945482	15945505	17	-	26627737	GBM cells	viability after 21 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	0.2743389892502781	[522]	[351,335]	3	hSpCas9	negative selection	1043172
15945524	15945547	17	+	26627737	GBM cells	viability after 21 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	-0.005116248100722642	[366]	[217,180]	0	hSpCas9	negative selection	1043173
15974736	15974759	17	-	26627737	GBM cells	viability after 21 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	0.8217121043504203	[250]	[263,219]	7	hSpCas9	negative selection	1043179
15974741	15974764	17	-	26627737	GBM cells	viability after 21 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.2463611984135558	[263]	[166,172]	2	hSpCas9	negative selection	1043180
15975021	15975044	17	-	26627737	GBM cells	viability after 21 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	0.37458581166626176	[265]	[178,194]	4	hSpCas9	negative selection	1043181
15975074	15975097	17	-	26627737	GBM cells	viability after 21 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.3788940819184786	[390]	[270,280]	4	hSpCas9	negative selection	1043182
15945482	15945505	17	-	26627737	RPE1	viability after 9 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.38369258599567135	[1724]	[378,458]	-3	hSpCas9	negative selection	1125487
15945524	15945547	17	+	26627737	RPE1	viability after 9 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	-0.6885756831038008	[1295]	[280,213]	-5	hSpCas9	negative selection	1125488
15974736	15974759	17	-	26627737	RPE1	viability after 9 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.0772560849870347	[768]	[170,301]	0	hSpCas9	negative selection	1125494
15974741	15974764	17	-	26627737	RPE1	viability after 9 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.13928758569876248	[708]	[195,306]	1	hSpCas9	negative selection	1125495
15975021	15975044	17	-	26627737	RPE1	viability after 9 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-1.3085871157139062	[1295]	[189,129]	-7	hSpCas9	negative selection	1125496
15975074	15975097	17	-	26627737	RPE1	viability after 9 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.10141563219301819	[1202]	[192,554]	0	hSpCas9	negative selection	1125497
15945482	15945505	17	-	26627737	RPE1	viability after 12 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.2670193757555017	[1724]	[406,361]	-2	hSpCas9	negative selection	1207802
15945524	15945547	17	+	26627737	RPE1	viability after 12 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	-0.26624786351357377	[1295]	[391,180]	-2	hSpCas9	negative selection	1207803
15974736	15974759	17	-	26627737	RPE1	viability after 12 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.35036957599413904	[768]	[146,177]	-2	hSpCas9	negative selection	1207809
15974741	15974764	17	-	26627737	RPE1	viability after 12 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.5685036943900343	[708]	[213,354]	4	hSpCas9	negative selection	1207810
15975021	15975044	17	-	26627737	RPE1	viability after 12 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-0.5228328405600187	[1295]	[236,247]	-4	hSpCas9	negative selection	1207811
15975074	15975097	17	-	26627737	RPE1	viability after 12 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.040507789205058264	[1202]	[203,430]	0	hSpCas9	negative selection	1207812
15945482	15945505	17	-	26627737	RPE1	viability after 15 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.22589873583699205	[1724]	[459,375]	-1	hSpCas9	negative selection	1290117
15945524	15945547	17	+	26627737	RPE1	viability after 15 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	-0.06688069145074371	[1295]	[377,322]	0	hSpCas9	negative selection	1290118
15974736	15974759	17	-	26627737	RPE1	viability after 15 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	0.033215935732816976	[768]	[216,227]	0	hSpCas9	negative selection	1290124
15974741	15974764	17	-	26627737	RPE1	viability after 15 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.6614753775326689	[708]	[191,437]	4	hSpCas9	negative selection	1290125
15975021	15975044	17	-	26627737	RPE1	viability after 15 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-0.430350315099492	[1295]	[268,274]	-3	hSpCas9	negative selection	1290126
15975074	15975097	17	-	26627737	RPE1	viability after 15 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.09445690391647854	[1202]	[147,570]	0	hSpCas9	negative selection	1290127
15945482	15945505	17	-	26627737	RPE1	viability after 18 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.2279443395455869	[1724]	[367,428]	-1	hSpCas9	negative selection	1372432
15945524	15945547	17	+	26627737	RPE1	viability after 18 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.018910276077438337	[1295]	[568,124]	0	hSpCas9	negative selection	1372433
15974736	15974759	17	-	26627737	RPE1	viability after 18 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.0535888607037089	[768]	[227,169]	0	hSpCas9	negative selection	1372439
15974741	15974764	17	-	26627737	RPE1	viability after 18 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.7936029139533463	[708]	[248,419]	5	hSpCas9	negative selection	1372440
15975021	15975044	17	-	26627737	RPE1	viability after 18 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-0.1696528308344556	[1295]	[323,296]	-1	hSpCas9	negative selection	1372441
15975074	15975097	17	-	26627737	RPE1	viability after 18 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.00178463111603	[1202]	[214,440]	0	hSpCas9	negative selection	1372442
15945482	15945505	17	-	26627737	HeLa	viability after 8 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.015059223334769056	[1136]	[328,592,509]	0	hSpCas9	negative selection	1454747
15945524	15945547	17	+	26627737	HeLa	viability after 8 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.46452044297445394	[492]	[402,292,220]	4	hSpCas9	negative selection	1454748
15974736	15974759	17	-	26627737	HeLa	viability after 8 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	1.2263450090673174	[237]	[162,237,303]	8	hSpCas9	negative selection	1454754
15974741	15974764	17	-	26627737	HeLa	viability after 8 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	1.086386944560905	[401]	[382,334,396]	8	hSpCas9	negative selection	1454755
15975021	15975044	17	-	26627737	HeLa	viability after 8 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	0.03422647363613185	[418]	[129,206,208]	0	hSpCas9	negative selection	1454756
15975074	15975097	17	-	26627737	HeLa	viability after 8 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.6088028244938805	[690]	[62,242,251]	-6	hSpCas9	negative selection	1454757
15945482	15945505	17	-	26627737	HeLa	viability after 12 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.25415493378977017	[1136]	[514,473,187]	-2	hSpCas9	negative selection	1537062
15945524	15945547	17	+	26627737	HeLa	viability after 12 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.20943424204794103	[492]	[256,200,252]	1	hSpCas9	negative selection	1537063
15974736	15974759	17	-	26627737	HeLa	viability after 12 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	1.5113221102033898	[237]	[332,201,315]	8	hSpCas9	negative selection	1537069
15974741	15974764	17	-	26627737	HeLa	viability after 12 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.3422375134836649	[401]	[159,213,255]	3	hSpCas9	negative selection	1537070
15975021	15975044	17	-	26627737	HeLa	viability after 12 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-0.5680213005664372	[418]	[195,47,115]	-5	hSpCas9	negative selection	1537071
15975074	15975097	17	-	26627737	HeLa	viability after 12 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.2683300398806253	[690]	[332,152,236]	-2	hSpCas9	negative selection	1537072
15945482	15945505	17	-	26627737	HeLa	viability after 15 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-1.0096448989858304	[1136]	[235,218,234]	-7	hSpCas9	negative selection	1619377
15945524	15945547	17	+	26627737	HeLa	viability after 15 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.5580781988924176	[492]	[232,313,343]	4	hSpCas9	negative selection	1619378
15974736	15974759	17	-	26627737	HeLa	viability after 15 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	1.4409380931516433	[237]	[255,224,311]	8	hSpCas9	negative selection	1619384
15974741	15974764	17	-	26627737	HeLa	viability after 15 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.4268085046715342	[401]	[356,107,190]	3	hSpCas9	negative selection	1619385
15975021	15975044	17	-	26627737	HeLa	viability after 15 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-1.2266738887967923	[418]	[4,123,91]	-8	hSpCas9	negative selection	1619386
15975074	15975097	17	-	26627737	HeLa	viability after 15 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.23693515465492354	[690]	[385,346,254]	2	hSpCas9	negative selection	1619387
15945482	15945505	17	-	26627737	HeLa	viability after 18 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.9879306109803795	[1136]	[166,178,234]	-7	hSpCas9	negative selection	1701692
15945524	15945547	17	+	26627737	HeLa	viability after 18 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.5278049092411167	[492]	[149,252,343]	4	hSpCas9	negative selection	1701693
15974736	15974759	17	-	26627737	HeLa	viability after 18 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	1.4549327869320607	[237]	[176,185,311]	8	hSpCas9	negative selection	1701699
15974741	15974764	17	-	26627737	HeLa	viability after 18 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.4359600773615542	[401]	[240,90,190]	3	hSpCas9	negative selection	1701700
15975021	15975044	17	-	26627737	HeLa	viability after 18 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-1.2358097337320204	[418]	[2,101,91]	-8	hSpCas9	negative selection	1701701
15975074	15975097	17	-	26627737	HeLa	viability after 18 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.227838037727217	[690]	[251,290,254]	2	hSpCas9	negative selection	1701702
15945482	15945505	17	-	26627737	HCT116	viability after 6 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	1.2595737350408371	[1061]	[964,87]	6	hSpCas9	negative selection	1784007
15945524	15945547	17	+	26627737	HCT116	viability after 6 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.8499485482573592	[1264]	[351,361]	5	hSpCas9	negative selection	1784008
15974736	15974759	17	-	26627737	HCT116	viability after 6 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	1.477921671398524	[206]	[89,90]	7	hSpCas9	negative selection	1784014
15974741	15974764	17	-	26627737	HCT116	viability after 6 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.29040161879000104	[1205]	[227,233]	1	hSpCas9	negative selection	1784015
15975021	15975044	17	-	26627737	HCT116	viability after 6 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-2.1475930571666635	[1455]	[99,24]	-8	hSpCas9	negative selection	1784016
15975074	15975097	17	-	26627737	HCT116	viability after 6 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-1.4654484439047921	[1682]	[167,55]	-7	hSpCas9	negative selection	1784017
15945482	15945505	17	-	26627737	HCT116	viability after 8 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.3205067108763576	[667]	[274,237,369]	-4	hSpCas9	negative selection	1866322
15945524	15945547	17	+	26627737	HCT116	viability after 8 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.5646050517712158	[324]	[324,233,236]	5	hSpCas9	negative selection	1866323
15974736	15974759	17	-	26627737	HCT116	viability after 8 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.11641548248059977	[376]	[153,209,209]	-1	hSpCas9	negative selection	1866329
15974741	15974764	17	-	26627737	HCT116	viability after 8 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.024786469119489896	[562]	[288,313,342]	0	hSpCas9	negative selection	1866330
15975021	15975044	17	-	26627737	HCT116	viability after 8 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-1.2625772575585317	[447]	[110,109,87]	-9	hSpCas9	negative selection	1866331
15975074	15975097	17	-	26627737	HCT116	viability after 8 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.33498293778039984	[350]	[143,175,139]	-4	hSpCas9	negative selection	1866332
15945482	15945505	17	-	26627737	HCT116	viability after 9 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	0.8481507211490079	[1061]	[357,630]	6	hSpCas9	negative selection	1948637
15945524	15945547	17	+	26627737	HCT116	viability after 9 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.276724124097389	[1264]	[516,323]	2	hSpCas9	negative selection	1948638
15974736	15974759	17	-	26627737	HCT116	viability after 9 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	1.1550736596073077	[206]	[188,70]	7	hSpCas9	negative selection	1948644
15974741	15974764	17	-	26627737	HCT116	viability after 9 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.2864333465572846	[1205]	[339,203]	-2	hSpCas9	negative selection	1948645
15975021	15975044	17	-	26627737	HCT116	viability after 9 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-1.2086318494879855	[1455]	[65,248]	-7	hSpCas9	negative selection	1948646
15975074	15975097	17	-	26627737	HCT116	viability after 9 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.9029367014568143	[1682]	[198,272]	-6	hSpCas9	negative selection	1948647
15945482	15945505	17	-	26627737	HCT116	viability after 12 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.12374217034937773	[667]	[346,428,190]	-1	hSpCas9	negative selection	2030952
15945524	15945547	17	+	26627737	HCT116	viability after 12 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.5440911264521273	[324]	[293,200,246]	5	hSpCas9	negative selection	2030953
15974736	15974759	17	-	26627737	HCT116	viability after 12 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.139236367564604	[376]	[190,232,115]	-1	hSpCas9	negative selection	2030959
15974741	15974764	17	-	26627737	HCT116	viability after 12 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.48545438428436893	[562]	[190,178,264]	-5	hSpCas9	negative selection	2030960
15975021	15975044	17	-	26627737	HCT116	viability after 12 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-1.3257935891723227	[447]	[58,141,84]	-8	hSpCas9	negative selection	2030961
15975074	15975097	17	-	26627737	HCT116	viability after 12 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.22408485820642066	[350]	[241,213,187]	2	hSpCas9	negative selection	2030962
15945482	15945505	17	-	26627737	HCT116	viability after 15 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	0.15067041766203948	[667]	[519,505,264]	1	hSpCas9	negative selection	2113267
15945524	15945547	17	+	26627737	HCT116	viability after 15 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.2183597651703515	[324]	[240,250,162]	2	hSpCas9	negative selection	2113268
15974736	15974759	17	-	26627737	HCT116	viability after 15 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.5034412307662817	[376]	[203,154,105]	-5	hSpCas9	negative selection	2113274
15974741	15974764	17	-	26627737	HCT116	viability after 15 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.20925266522113684	[562]	[312,160,367]	-2	hSpCas9	negative selection	2113275
15975021	15975044	17	-	26627737	HCT116	viability after 15 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-1.1014833206855896	[447]	[224,68,78]	-8	hSpCas9	negative selection	2113276
15975074	15975097	17	-	26627737	HCT116	viability after 15 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.6415520816568226	[350]	[291,362,285]	6	hSpCas9	negative selection	2113277
15945482	15945505	17	-	26627737	HCT116	viability after 18 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	0.6640658093750136	[667]	[528,565,432]	5	hSpCas9	negative selection	2195582
15945524	15945547	17	+	26627737	HCT116	viability after 18 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.6293836970937172	[324]	[198,193,343]	5	hSpCas9	negative selection	2195583
15974736	15974759	17	-	26627737	HCT116	viability after 18 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	0.020533022125684086	[376]	[199,183,169]	0	hSpCas9	negative selection	2195589
15974741	15974764	17	-	26627737	HCT116	viability after 18 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	0.4537019420953692	[562]	[374,305,444]	4	hSpCas9	negative selection	2195590
15975021	15975044	17	-	26627737	HCT116	viability after 18 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-0.6907021743489217	[447]	[214,62,128]	-6	hSpCas9	negative selection	2195591
15975074	15975097	17	-	26627737	HCT116	viability after 18 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	1.221390913136683	[350]	[524,376,280]	8	hSpCas9	negative selection	2195592
15949743	15949766	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAGTTACTAGG	ADORA2B	ENSG00000170425	-1.4499740674906352	[80,484]	[11,33]	-8	dCas9-VP64	positive selection	2386037
15949743	15949766	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAGTTACTAGG	ADORA2B	ENSG00000170425	0.5129370309291919	[140,116]	[29,88]	4	dCas9-VP64	positive selection	2481292
15945488	15945511	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.4574170201182038	[1,1]	[0,3]	8	hSpCas9	positive selection	2969171
15945412	15945435	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGGATGGCGAAGAGCCCCACGG	ADORA2B	ENSG00000170425	-0.6608679872485816	[4,3]	[2,1]	-7	hSpCas9	positive selection	2969172
15945301	15945324	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.6903470337282114	[2,3]	[2,0]	-8	hSpCas9	positive selection	2969173
15974812	15974835	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCATTCGTGGTTCCATCCCAGGG	ADORA2B	ENSG00000170425	-0.07442259073269775	[4,4]	[3,2]	-1	hSpCas9	positive selection	2969174
15945488	15945511	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	1.6334601346056754	[1,1]	[3,4]	9	hSpCas9	positive selection	3037029
15945412	15945435	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGGATGGCGAAGAGCCCCACGG	ADORA2B	ENSG00000170425	-0.045080317313006185	[4,4]	[2,2]	0	hSpCas9	positive selection	3037030
15945301	15945324	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.20865901802677586	[2,2]	[2,2]	3	hSpCas9	positive selection	3037031
15974812	15974835	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCATTCGTGGTTCCATCCCAGGG	ADORA2B	ENSG00000170425	-0.1715444965589186	[4,4]	[3,1]	-3	hSpCas9	positive selection	3037032
15945296	15945319		+	24336571	A375	resistance to PLX after 7 days	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.4268743665826472	[7,7]	[10,10]	9	hSpCas9	positive selection	3106810
15974748	15974771		+	24336571	A375	resistance to PLX after 7 days	CATCGGATTGACTCCATTCCTGG	ADORA2B	ENSG00000170425	-0.014634290295777563	[20,21]	[21,20]	0	hSpCas9	positive selection	3106818
15975203	15975226		-	24336571	A375	resistance to PLX after 7 days	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.3377326760841689	[10,11]	[9,7]	-8	hSpCas9	positive selection	3106829
15945301	15945324		-	24336571	A375	resistance to PLX after 7 days	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.0950128577194791	[8,6]	[6,7]	-3	hSpCas9	positive selection	3106840
15945296	15945319		+	24336571	A375	resistance to PLX after 14 days	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.35288692564328256	[12,5]	[4,5]	3	hSpCas9	positive selection	3164603
15974748	15974771		+	24336571	A375	resistance to PLX after 14 days	CATCGGATTGACTCCATTCCTGG	ADORA2B	ENSG00000170425	-1.3601274481861982	[28,20]	[4,2]	-9	hSpCas9	positive selection	3164611
15975203	15975226		-	24336571	A375	resistance to PLX after 14 days	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.6221942093365322	[8,7]	[1,1]	-7	hSpCas9	positive selection	3164622
15945301	15945324		-	24336571	A375	resistance to PLX after 14 days	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.7133425474370745	[6,3]	[3,3]	6	hSpCas9	positive selection	3164633
15945296	15945319		+	24336571	A375	viability after 7 days	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.01956779482570359	[7]	[7,7]	0	hSpCas9	negative selection	3222396
15974748	15974771		+	24336571	A375	viability after 7 days	CATCGGATTGACTCCATTCCTGG	ADORA2B	ENSG00000170425	0.270788034745101	[18]	[20,21]	4	hSpCas9	negative selection	3222404
15975203	15975226		-	24336571	A375	viability after 7 days	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.39053910532372915	[8]	[10,11]	6	hSpCas9	negative selection	3222415
15945301	15945324		-	24336571	A375	viability after 7 days	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.655369258309855	[4]	[8,6]	8	hSpCas9	negative selection	3222426
15945296	15945319		+	24336571	A375	viability after 14 days	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.24025160322585548	[7]	[12,5]	3	hSpCas9	negative selection	3280189
15974748	15974771		+	24336571	A375	viability after 14 days	CATCGGATTGACTCCATTCCTGG	ADORA2B	ENSG00000170425	0.4907908360701669	[18]	[28,20]	6	hSpCas9	negative selection	3280197
15975203	15975226		-	24336571	A375	viability after 14 days	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.010962139113815383	[8]	[8,7]	0	hSpCas9	negative selection	3280208
15945301	15945324		-	24336571	A375	viability after 14 days	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.1547218703407378	[4]	[6,3]	2	hSpCas9	negative selection	3280219
15945296	15945319	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	-0.2660307435393034	[179,187]	[0,0]	-2	hSpCas9	positive selection	3335758
15945301	15945324	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	2.04991307248307	[28,44]	[0,0]	7	hSpCas9	positive selection	3335759
15975203	15975226	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	1.0280047083489288	[78,70]	[0,0]	4	hSpCas9	positive selection	3335760
15975319	15975342	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	0.28004628794591846	[125,125]	[0,0]	1	hSpCas9	positive selection	3355007
15945541	15945564	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.4150991305256606	[203,203]	[0,0]	-3	hSpCas9	positive selection	3355008
15945365	15945388	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	-0.7256673632484749	[252,252]	[0,0]	-5	hSpCas9	positive selection	3355009
15945488	15945511	17	-	26780180	HT29	viability (Avana library 4 designs)	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.729917984572663	[]	[]	3	hSpCas9	negative selection	3405235
15945412	15945435	17	-	26780180	HT29	viability (Avana library 4 designs)	GGGGATGGCGAAGAGCCCCACGG	ADORA2B	ENSG00000170425	0.742389968265547	[]	[]	3	hSpCas9	negative selection	3405236
15945301	15945324	17	-	26780180	HT29	viability (Avana library 4 designs)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.707980154727424	[]	[]	2	hSpCas9	negative selection	3405237
15974812	15974835	17	-	26780180	HT29	viability (Avana library 4 designs)	TCATTCGTGGTTCCATCCCAGGG	ADORA2B	ENSG00000170425	0.0617602479976444	[]	[]	0	hSpCas9	negative selection	3405238
15945412	15945435	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGGATGGCGAAGAGCCCCACGG	ADORA2B	ENSG00000170425	4.071497746107	[]	[]	6	hSpCas9	negative selection	3477149
15945301	15945324	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	4.82649938822072	[]	[]	8	hSpCas9	negative selection	3477150
15974812	15974835	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCATTCGTGGTTCCATCCCAGGG	ADORA2B	ENSG00000170425	-4.57220195888485	[]	[]	-5	hSpCas9	negative selection	3477151
15945488	15945511	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	-2.11885401154442	[]	[]	-3	hSpCas9	negative selection	3477152
15945337	15945360	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	4.27768306933875	[]	[]	7	hSpCas9	negative selection	3477153
15945320	15945343	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	6.34701347364565	[]	[]	9	hSpCas9	negative selection	3477154
15945412	15945435	17	-	26780180	A375	viability (Avana lentiGuide)	GGGGATGGCGAAGAGCCCCACGG	ADORA2B	ENSG00000170425	-2.17331756769938	[]	[]	-4	hSpCas9	negative selection	3585808
15945301	15945324	17	-	26780180	A375	viability (Avana lentiGuide)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	7.03843805399302	[]	[]	5	hSpCas9	negative selection	3585809
15974812	15974835	17	-	26780180	A375	viability (Avana lentiGuide)	TCATTCGTGGTTCCATCCCAGGG	ADORA2B	ENSG00000170425	3.04643253648471	[]	[]	3	hSpCas9	negative selection	3585810
15945488	15945511	17	-	26780180	A375	viability (Avana lentiGuide)	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	-9.51746509751675	[]	[]	-9	hSpCas9	negative selection	3585811
15945337	15945360	17	-	26780180	A375	viability (Avana lentiGuide)	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	-1.0482473649355	[]	[]	-2	hSpCas9	negative selection	3585812
15945320	15945343	17	+	26780180	A375	viability (Avana lentiGuide)	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	-3.11698710866952	[]	[]	-5	hSpCas9	negative selection	3585813
15945412	15945435	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGGATGGCGAAGAGCCCCACGG	ADORA2B	ENSG00000170425	0.20760464708174192	[5]	[6,6]	6	hSpCas9	positive selection	3694467
15945301	15945324	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.2490512791388262	[4]	[6,4]	7	hSpCas9	positive selection	3694468
15974812	15974835	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATTCGTGGTTCCATCCCAGGG	ADORA2B	ENSG00000170425	-0.5480784843759212	[5]	[3,2]	-7	hSpCas9	positive selection	3694469
15945488	15945511	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.19008136644091955	[3]	[4,3]	5	hSpCas9	positive selection	3694470
15945337	15945360	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.37954235787157337	[4]	[5,5]	9	hSpCas9	positive selection	3694471
15945320	15945343	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.2827037970639997	[4]	[5,5]	7	hSpCas9	positive selection	3694472
15945412	15945435	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGGATGGCGAAGAGCCCCACGG	ADORA2B	ENSG00000170425	0.24654389302717622	[5]	[5,6]	6	hSpCas9	positive selection	3803074
15945301	15945324	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.09519628171755445	[5]	[4,4]	-1	hSpCas9	positive selection	3803075
15974812	15974835	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATTCGTGGTTCCATCCCAGGG	ADORA2B	ENSG00000170425	0.14227307378211668	[6]	[5,5]	3	hSpCas9	positive selection	3803076
15945488	15945511	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.2894144410348163	[2]	[2,2]	7	hSpCas9	positive selection	3803077
15945337	15945360	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.22132558593249924	[4]	[5,4]	5	hSpCas9	positive selection	3803078
15945320	15945343	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	-0.13444157392521627	[4]	[4,1]	-2	hSpCas9	positive selection	3803079
15945541	15945564	17	-	26780180	A375	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	1.50470982820071	[]	[]	8	hSpCas9	negative selection	3911533
15975319	15975342	17	-	26780180	A375	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	1.73708349513978	[]	[]	9	hSpCas9	negative selection	3911534
15945296	15945319	17	+	26780180	A375	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.782009703023299	[]	[]	3	hSpCas9	negative selection	3911535
15945365	15945388	17	+	26780180	A375	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.787896844677814	[]	[]	3	hSpCas9	negative selection	3911536
15975203	15975226	17	-	26780180	A375	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	1.21737228151474	[]	[]	6	hSpCas9	negative selection	3911537
15945301	15945324	17	-	26780180	A375	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.725099459173571	[]	[]	2	hSpCas9	negative selection	3911538
15945541	15945564	17	-	26780180	HT29	viability (GeCKOv2 library)	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.792417817021059	[]	[]	3	hSpCas9	negative selection	4019499
15975319	15975342	17	-	26780180	HT29	viability (GeCKOv2 library)	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	2.07635112956972	[]	[]	9	hSpCas9	negative selection	4019500
15945296	15945319	17	+	26780180	HT29	viability (GeCKOv2 library)	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	-0.0722057362512005	[]	[]	-2	hSpCas9	negative selection	4019501
15945365	15945388	17	+	26780180	HT29	viability (GeCKOv2 library)	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	1.2084029726365	[]	[]	6	hSpCas9	negative selection	4019502
15975203	15975226	17	-	26780180	HT29	viability (GeCKOv2 library)	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.900947515199955	[]	[]	4	hSpCas9	negative selection	4019503
15945301	15945324	17	-	26780180	HT29	viability (GeCKOv2 library)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.730008996845954	[]	[]	3	hSpCas9	negative selection	4019504
15945296	15945319	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.0998499281398051	[3]	[2,2]	2	hSpCas9	positive selection	4129017
15974748	15974771	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATCGGATTGACTCCATTCCTGG	ADORA2B	ENSG00000170425	-0.10215014785271845	[4]	[2,1]	-2	hSpCas9	positive selection	4129028
15975203	15975226	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.5031825545418469	[3]	[2,0]	-8	hSpCas9	positive selection	4129039
15945301	15945324	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.15698234444608897	[3]	[1,1]	-4	hSpCas9	positive selection	4129050
15945296	15945319	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.4222628642885427	[2]	[2,2,0,0]	3	hSpCas9	positive selection	4193039
15974748	15974771	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATCGGATTGACTCCATTCCTGG	ADORA2B	ENSG00000170425	1.2383399706933598	[4]	[4,4,3,4]	8	hSpCas9	positive selection	4193050
15975203	15975226	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.7020836408125831	[3]	[2,0,0,3]	4	hSpCas9	positive selection	4193061
15945301	15945324	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.48959072027912987	[3]	[0,0,1,0]	-7	hSpCas9	positive selection	4193072
15945296	15945319	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.6172371551569548	[3]	[3,4]	9	hSpCas9	positive selection	4254719
15945301	15945324	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.4406951014468278	[1]	[2,1]	8	hSpCas9	positive selection	4254720
15975203	15975226	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.28919143298995087	[2]	[2,1]	6	hSpCas9	positive selection	4254721
15975319	15975342	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.14577638173460133	[2]	[2,1]	-3	hSpCas9	positive selection	4319001
15945541	15945564	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.02785147572786323	[3]	[3,1]	0	hSpCas9	positive selection	4319002
15945365	15945388	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.040324030039872324	[3]	[2,2]	0	hSpCas9	positive selection	4319003
15945525	15945547	17	+	27760321	OCIAML3	viability	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.5281498483887763	[942,935]	[1070,1051]	6	hSpCas9	negative selection	4376471
15945541	15945563	17	-	27760321	OCIAML3	viability	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.49537045410620933	[619,606]	[575,810]	6	hSpCas9	negative selection	4376472
15974751	15974773	17	+	27760321	OCIAML3	viability	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	0.29118702280952247	[503,472]	[347,623]	3	hSpCas9	negative selection	4376473
15974922	15974944	17	-	27760321	OCIAML3	viability	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.0014660102035414235	[318,241]	[229,201]	0	hSpCas9	negative selection	4376474
15974991	15975013	17	+	27760321	OCIAML3	viability	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	1.1788895471294403	[697,531]	[964,1230]	9	hSpCas9	negative selection	4376475
15945525	15945547	17	+	27760321	OCIAML2	viability	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.6311824271589779	[942,935]	[1064,1332]	8	hSpCas9	negative selection	4459934
15945541	15945563	17	-	27760321	OCIAML2	viability	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.20454731544840882	[619,606]	[511,653]	2	hSpCas9	negative selection	4459935
15974751	15974773	17	+	27760321	OCIAML2	viability	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	-0.034123218499459165	[503,472]	[314,479]	0	hSpCas9	negative selection	4459936
15974922	15974944	17	-	27760321	OCIAML2	viability	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.017951722394949132	[318,241]	[176,294]	0	hSpCas9	negative selection	4459937
15974991	15975013	17	+	27760321	OCIAML2	viability	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.6744869032494167	[697,531]	[704,896]	8	hSpCas9	negative selection	4459938
15945525	15945547	17	+	27760321	MV411	viability	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.6742428074005102	[942,935]	[847,1208]	5	hSpCas9	negative selection	4543397
15945541	15945563	17	-	27760321	MV411	viability	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	1.608329555392668	[619,606]	[1670,585]	9	hSpCas9	negative selection	4543398
15974751	15974773	17	+	27760321	MV411	viability	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	-0.15893810131139996	[503,472]	[204,414]	-1	hSpCas9	negative selection	4543399
15974922	15974944	17	-	27760321	MV411	viability	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.06612792276513813	[318,241]	[236,124]	0	hSpCas9	negative selection	4543400
15974991	15975013	17	+	27760321	MV411	viability	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	1.5702645232785046	[697,531]	[1174,1226]	9	hSpCas9	negative selection	4543401
15945525	15945547	17	+	27760321	HL60	viability	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	1.3847395710997814	[942,935]	[1760,2273]	9	hSpCas9	negative selection	4626860
15945541	15945563	17	-	27760321	HL60	viability	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.03198892211292165	[619,606]	[434,596]	0	hSpCas9	negative selection	4626861
15974751	15974773	17	+	27760321	HL60	viability	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	-0.22032491360352735	[503,472]	[367,315]	-2	hSpCas9	negative selection	4626862
15974922	15974944	17	-	27760321	HL60	viability	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.47233124670395876	[318,241]	[326,302]	6	hSpCas9	negative selection	4626863
15974991	15975013	17	+	27760321	HL60	viability	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.12219529340779306	[697,531]	[592,488]	1	hSpCas9	negative selection	4626864
15945525	15945547	17	+	27760321	HT1080	viability	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	1.174762120856995	[935,730]	[1036,434]	6	hSpCas9	negative selection	4710323
15945541	15945563	17	-	27760321	HT1080	viability	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.5780159673583145	[606,473]	[180,103]	-3	hSpCas9	negative selection	4710324
15974751	15974773	17	+	27760321	HT1080	viability	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	0.825530355237174	[472,368]	[248,349]	4	hSpCas9	negative selection	4710325
15974922	15974944	17	-	27760321	HT1080	viability	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	-0.12548930092115296	[241,188]	[103,50]	0	hSpCas9	negative selection	4710326
15974991	15975013	17	+	27760321	HT1080	viability	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.03369684490689506	[531,414]	[257,121]	0	hSpCas9	negative selection	4710327
15945525	15945547	17	+	27760321	HT29	viability after 7 days	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	-0.06455478471877374	[935,730]	[1245,1010,852]	-1	hSpCas9	negative selection	4793786
15945541	15945563	17	-	27760321	HT29	viability after 7 days	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.08387151339690369	[606,473]	[775,567,865]	1	hSpCas9	negative selection	4793787
15974751	15974773	17	+	27760321	HT29	viability after 7 days	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	-0.1380543985261123	[472,368]	[345,548,556]	-2	hSpCas9	negative selection	4793788
15974922	15974944	17	-	27760321	HT29	viability after 7 days	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.9373798315890725	[241,188]	[584,582,433]	9	hSpCas9	negative selection	4793789
15974991	15975013	17	+	27760321	HT29	viability after 7 days	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.21137653517341837	[531,414]	[815,725,590]	3	hSpCas9	negative selection	4793790
15945525	15945547	17	+	27760321	HT29	viability after 25 days	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.3891551948760743	[935,730]	[972,1252,1564]	4	hSpCas9	negative selection	4877249
15945541	15945563	17	-	27760321	HT29	viability after 25 days	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.038004239366201786	[606,473]	[731,343,840]	0	hSpCas9	negative selection	4877250
15974751	15974773	17	+	27760321	HT29	viability after 25 days	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	-0.06485079091139614	[472,368]	[283,622,485]	0	hSpCas9	negative selection	4877251
15974922	15974944	17	-	27760321	HT29	viability after 25 days	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.9568171229644021	[241,188]	[494,427,512]	9	hSpCas9	negative selection	4877252
15974991	15975013	17	+	27760321	HT29	viability after 25 days	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.6195462712863038	[531,414]	[690,803,1026]	7	hSpCas9	negative selection	4877253
15945525	15945547	17	+	27760321	HT29	viability after 22 days	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.2729825610569079	[935,730]	[972,1267,1257]	3	hSpCas9	negative selection	4960712
15945541	15945563	17	-	27760321	HT29	viability after 22 days	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.017123962638907253	[606,473]	[567,541,744]	0	hSpCas9	negative selection	4960713
15974751	15974773	17	+	27760321	HT29	viability after 22 days	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	0.11633498786890661	[472,368]	[521,406,654]	1	hSpCas9	negative selection	4960714
15974922	15974944	17	-	27760321	HT29	viability after 22 days	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.9382293420477403	[241,188]	[389,621,421]	9	hSpCas9	negative selection	4960715
15974991	15975013	17	+	27760321	HT29	viability after 22 days	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.8018349939300153	[531,414]	[949,833,1079]	8	hSpCas9	negative selection	4960716
15945525	15945547	17	+	27760321	HT29	viability after 19 days	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.3583027373228307	[935,730]	[1257,972,1429]	3	hSpCas9	negative selection	5044175
15945541	15945563	17	-	27760321	HT29	viability after 19 days	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.15998391249988164	[606,473]	[855,410,428]	-1	hSpCas9	negative selection	5044176
15974751	15974773	17	+	27760321	HT29	viability after 19 days	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	0.7144865516550095	[472,368]	[449,610,1254]	7	hSpCas9	negative selection	5044177
15974922	15974944	17	-	27760321	HT29	viability after 19 days	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.8516251872479921	[241,188]	[289,373,645]	8	hSpCas9	negative selection	5044178
15974991	15975013	17	+	27760321	HT29	viability after 19 days	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.8005147486342079	[531,414]	[1273,659,929]	7	hSpCas9	negative selection	5044179
15945525	15945547	17	+	27760321	HT29	viability after 16 days	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.29618385577621664	[935,730]	[1018,1112,1291]	3	hSpCas9	negative selection	5127638
15945541	15945563	17	-	27760321	HT29	viability after 16 days	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.04322184544334495	[606,473]	[659,489,619]	0	hSpCas9	negative selection	5127639
15974751	15974773	17	+	27760321	HT29	viability after 16 days	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	0.4426726516964009	[472,368]	[428,578,893]	5	hSpCas9	negative selection	5127640
15974922	15974944	17	-	27760321	HT29	viability after 16 days	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	1.1282462805395221	[241,188]	[498,351,731]	9	hSpCas9	negative selection	5127641
15974991	15975013	17	+	27760321	HT29	viability after 16 days	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.7594942740017223	[531,414]	[793,1337,536]	8	hSpCas9	negative selection	5127642
15945525	15945547	17	+	27760321	HT29	viability after 13 days	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.40034579370815804	[935,730]	[1489,1282,1067]	5	hSpCas9	negative selection	5211101
15945541	15945563	17	-	27760321	HT29	viability after 13 days	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.12712896985288813	[606,473]	[687,525,511]	-1	hSpCas9	negative selection	5211102
15974751	15974773	17	+	27760321	HT29	viability after 13 days	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	0.0032109963232066496	[472,368]	[485,554,430]	0	hSpCas9	negative selection	5211103
15974922	15974944	17	-	27760321	HT29	viability after 13 days	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.5014162287982667	[241,188]	[301,374,382]	6	hSpCas9	negative selection	5211104
15974991	15975013	17	+	27760321	HT29	viability after 13 days	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.7610220780832315	[531,414]	[1036,990,773]	8	hSpCas9	negative selection	5211105
15945525	15945547	17	+	27760321	HT29	viability after 10 days	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.11500685688680212	[935,730]	[1145,1117,1116]	1	hSpCas9	negative selection	5294564
15945541	15945563	17	-	27760321	HT29	viability after 10 days	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.16353331785599212	[606,473]	[791,709,763]	2	hSpCas9	negative selection	5294565
15974751	15974773	17	+	27760321	HT29	viability after 10 days	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	0.13315058148601205	[472,368]	[346,633,745]	1	hSpCas9	negative selection	5294566
15974922	15974944	17	-	27760321	HT29	viability after 10 days	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.8978060137677042	[241,188]	[303,409,780]	9	hSpCas9	negative selection	5294567
15974991	15975013	17	+	27760321	HT29	viability after 10 days	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	0.8784530693493617	[531,414]	[1160,1328,783]	9	hSpCas9	negative selection	5294568
15945525	15945547	17	+	27760321	MOLM13	viability	ATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.431125021301102	[942,935]	[1048,433]	3	hSpCas9	negative selection	5378027
15945541	15945563	17	-	27760321	MOLM13	viability	AGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.8613586380188005	[619,606]	[443,788]	6	hSpCas9	negative selection	5378028
15974751	15974773	17	+	27760321	MOLM13	viability	CGGATTGACTCCATTCCTGGGG	ADORA2B	ENSG00000170425	-0.5059196176952846	[503,472]	[197,190]	-3	hSpCas9	negative selection	5378029
15974922	15974944	17	-	27760321	MOLM13	viability	CACCAGCATTATAAGCAGTGGG	ADORA2B	ENSG00000170425	0.01586255650271895	[318,241]	[195,126]	0	hSpCas9	negative selection	5378030
15974991	15975013	17	+	27760321	MOLM13	viability	TGAGCTGATGGACCACTCGAGG	ADORA2B	ENSG00000170425	1.0825315892910015	[697,531]	[1238,294]	7	hSpCas9	negative selection	5378031
15945260	15945283	17	+	27661255	K562	viability	GACACAGGACGCGCTGTACGTGG	ADORA2B	ENSG00000170425	0.09709974281208825	[733,895]	[749,645]	3	dCas9-KRAB	negative selection	5461153
15945324	15945347	17	+	27661255	K562	viability	GTGCTGGTGTGCGCCGCGGTGGG	ADORA2B	ENSG00000170425	-0.016506710033288824	[767,886]	[728,585]	0	dCas9-KRAB	negative selection	5461154
15945456	15945479	17	+	27661255	K562	viability	GGCTTCTGCACTGACTTCTACGG	ADORA2B	ENSG00000170425	0.1716886241796643	[693,853]	[736,656]	6	dCas9-KRAB	negative selection	5461155
15945614	15945637	17	+	27661255	K562	viability	GCCCCGTCGGAGCTCCGAAATGG	ADORA2B	ENSG00000170425	-0.3836681991005585	[671,699]	[443,398]	-7	dCas9-KRAB	negative selection	5461156
15945369	15945392	17	-	27661255	K562	viability	GACACCAGGAAGTAGTTGGTGGG	ADORA2B	ENSG00000170425	0.1828176896132505	[162,246]	[224,149]	6	dCas9-KRAB	negative selection	5461157
15945652	15945675	17	-	27661255	K562	viability	GGCCCCCGAGGGAGGAACCCCGG	ADORA2B	ENSG00000170425	-1.177664542240318	[734,536]	[254,200]	-8	dCas9-KRAB	negative selection	5461158
15945674	15945697	17	-	27661255	K562	viability	GCCCCCAGCCTGGCCCGTCTGGG	ADORA2B	ENSG00000170425	0.02219516775743169	[317,205]	[265,169]	0	dCas9-KRAB	negative selection	5461159
15945296	15945319	17	+	27260156	BXPC3	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.4861264890592549	[577]	[801,661,909,1047]	8	hSpCas9	negative selection	5527179
15945301	15945324	17	-	27260156	BXPC3	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.09164243899362212	[163]	[166,147,222,197]	2	hSpCas9	negative selection	5527180
15975203	15975226	17	-	27260156	BXPC3	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.15056603731568763	[202]	[130,197,190,257]	-3	hSpCas9	negative selection	5527181
15975319	15975342	17	-	27260156	BXPC3	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.3448320256516122	[432]	[339,260,409,429]	-6	hSpCas9	negative selection	5591461
15945541	15945564	17	-	27260156	BXPC3	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.05866795052481133	[667]	[733,649,737,794]	1	hSpCas9	negative selection	5591462
15945365	15945388	17	+	27260156	BXPC3	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.2755384636993015	[617]	[724,838,744,820]	6	hSpCas9	negative selection	5591463
15945296	15945319	17	+	27260156	A673	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.4495374659809906	[577]	[958,921,917,994]	8	hSpCas9	negative selection	5648430
15945301	15945324	17	-	27260156	A673	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.162075573098452	[163]	[215,240,158,266]	4	hSpCas9	negative selection	5648431
15975203	15975226	17	-	27260156	A673	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.1604804365868362	[202]	[369,229,242,257]	4	hSpCas9	negative selection	5648432
15975319	15975342	17	-	27260156	A673	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.24022065733879744	[432]	[493,485,398,382]	-5	hSpCas9	negative selection	5712712
15945541	15945564	17	-	27260156	A673	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.04272846275123243	[667]	[793,760,966,774]	1	hSpCas9	negative selection	5712713
15945365	15945388	17	+	27260156	A673	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.06132529131414244	[617]	[838,656,769,843]	1	hSpCas9	negative selection	5712714
15945296	15945319	17	+	27260156	A375	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.4469612072738977	[577]	[969,1025,955,759]	6	hSpCas9	negative selection	5769681
15945301	15945324	17	-	27260156	A375	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.2102198318168138	[163]	[276,224,232,158]	3	hSpCas9	negative selection	5769682
15975203	15975226	17	-	27260156	A375	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.5343590252171079	[202]	[256,359,284,457]	7	hSpCas9	negative selection	5769683
15975319	15975342	17	-	27260156	A375	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.33131422239997854	[432]	[437,296,482,376]	-5	hSpCas9	negative selection	5833963
15945541	15945564	17	-	27260156	A375	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.22012456627379867	[667]	[704,769,593,626]	-3	hSpCas9	negative selection	5833964
15945365	15945388	17	+	27260156	A375	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.5418304550377162	[617]	[796,1313,1210,926]	7	hSpCas9	negative selection	5833965
15945296	15945319	17	+	27260156	COLO741	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.3719782036864609	[577]	[901,1091,872]	7	hSpCas9	negative selection	5890932
15945301	15945324	17	-	27260156	COLO741	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.3050548352566209	[163]	[346,269,172]	6	hSpCas9	negative selection	5890933
15975203	15975226	17	-	27260156	COLO741	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.23560028256594578	[202]	[311,367,240]	5	hSpCas9	negative selection	5890934
15975319	15975342	17	-	27260156	COLO741	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.13917316831365256	[432]	[481,473,544]	-3	hSpCas9	negative selection	5955214
15945541	15945564	17	-	27260156	COLO741	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.16743186185578124	[667]	[773,683,816]	-4	hSpCas9	negative selection	5955215
15945365	15945388	17	+	27260156	COLO741	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.1685155999915477	[617]	[893,991,782]	3	hSpCas9	negative selection	5955216
15945296	15945319	17	+	27260156	CAL120	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.5338715985993907	[577]	[1022,1232,867]	7	hSpCas9	negative selection	6012183
15945301	15945324	17	-	27260156	CAL120	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.6436003157630765	[163]	[481,298,201]	8	hSpCas9	negative selection	6012184
15975203	15975226	17	-	27260156	CAL120	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.1349963436011925	[202]	[179,187,312]	-2	hSpCas9	negative selection	6012185
15975319	15975342	17	-	27260156	CAL120	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.5523870920977966	[432]	[227,478,373]	-7	hSpCas9	negative selection	6076465
15945541	15945564	17	-	27260156	CAL120	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.10432429611321636	[667]	[791,740,788]	-1	hSpCas9	negative selection	6076466
15945365	15945388	17	+	27260156	CAL120	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.3402828782779949	[617]	[1245,720,993]	5	hSpCas9	negative selection	6076467
15945296	15945319	17	+	27260156	CADOES1	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.45779753010105545	[577]	[699,809,744,696]	7	hSpCas9	negative selection	6133434
15945301	15945324	17	-	27260156	CADOES1	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.04963958335450935	[163]	[85,145,180,220]	0	hSpCas9	negative selection	6133435
15975203	15975226	17	-	27260156	CADOES1	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.19800944598018577	[202]	[220,268,195,178]	3	hSpCas9	negative selection	6133436
15975319	15975342	17	-	27260156	CADOES1	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.5145617800173077	[432]	[354,236,312,219]	-7	hSpCas9	negative selection	6197716
15945541	15945564	17	-	27260156	CADOES1	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.3556815112986847	[667]	[465,429,484,563]	-6	hSpCas9	negative selection	6197717
15945365	15945388	17	+	27260156	CADOES1	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.5691922597117849	[617]	[848,636,1139,781]	8	hSpCas9	negative selection	6197718
15945296	15945319	17	+	27260156	EWS502	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.42942114202559906	[577]	[630,832,1009,847]	7	hSpCas9	negative selection	6254685
15945301	15945324	17	-	27260156	EWS502	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.18431056289747771	[163]	[175,226,205,179]	3	hSpCas9	negative selection	6254686
15975203	15975226	17	-	27260156	EWS502	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.2654208777497433	[202]	[236,280,232,284]	4	hSpCas9	negative selection	6254687
15975319	15975342	17	-	27260156	EWS502	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.4394545982858986	[432]	[337,342,238,436]	-6	hSpCas9	negative selection	6318967
15945541	15945564	17	-	27260156	EWS502	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.0675438596773808	[667]	[599,659,856,586]	-1	hSpCas9	negative selection	6318968
15945365	15945388	17	+	27260156	EWS502	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.20081172933043873	[617]	[639,837,834,700]	3	hSpCas9	negative selection	6318969
15945296	15945319	17	+	27260156	EW8	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.6833456525412351	[577]	[1008,726,646,669]	9	hSpCas9	negative selection	6375936
15945301	15945324	17	-	27260156	EW8	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.35636337881606805	[163]	[133,121,167,251]	6	hSpCas9	negative selection	6375937
15975203	15975226	17	-	27260156	EW8	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.5311792892393582	[202]	[301,196,160,309]	8	hSpCas9	negative selection	6375938
15975319	15975342	17	-	27260156	EW8	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.4947362063695183	[432]	[270,303,196,234]	-7	hSpCas9	negative selection	6440218
15945541	15945564	17	-	27260156	EW8	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.13509562452668283	[667]	[597,543,412,440]	-3	hSpCas9	negative selection	6440219
15945365	15945388	17	+	27260156	EW8	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.260490784935746	[617]	[463,534,726,634]	5	hSpCas9	negative selection	6440220
15945296	15945319	17	+	27260156	CORL105	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.5598611239353437	[577]	[948,911,1134,1014]	8	hSpCas9	negative selection	6497187
15945301	15945324	17	-	27260156	CORL105	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.5074621099222958	[163]	[289,274,258,265]	8	hSpCas9	negative selection	6497188
15975203	15975226	17	-	27260156	CORL105	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.0019545133280276517	[202]	[194,217,312,233]	0	hSpCas9	negative selection	6497189
15975319	15975342	17	-	27260156	CORL105	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.32791762551690956	[432]	[393,413,411,395]	-6	hSpCas9	negative selection	6561469
15945541	15945564	17	-	27260156	CORL105	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.019486788852931536	[667]	[712,721,1002,763]	0	hSpCas9	negative selection	6561470
15945365	15945388	17	+	27260156	CORL105	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.25525794598782076	[617]	[1035,749,1043,660]	5	hSpCas9	negative selection	6561471
15945296	15945319	17	+	27260156	HS294T	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.13409891632107435	[577]	[243,223,227,292]	1	hSpCas9	negative selection	6618438
15945301	15945324	17	-	27260156	HS294T	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.45792484576456993	[163]	[122,74,54,92]	6	hSpCas9	negative selection	6618439
15975203	15975226	17	-	27260156	HS294T	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.8862808901304489	[202]	[38,60,28,39]	-8	hSpCas9	negative selection	6618440
15975319	15975342	17	-	27260156	HS294T	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	0.914451796311266	[432]	[161,713,222,132]	9	hSpCas9	negative selection	6682720
15945541	15945564	17	-	27260156	HS294T	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.3669902193794843	[667]	[182,225,167,228]	-5	hSpCas9	negative selection	6682721
15945365	15945388	17	+	27260156	HS294T	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.2578113657044298	[617]	[266,272,218,404]	3	hSpCas9	negative selection	6682722
15945296	15945319	17	+	27260156	HCC44	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.43627951129942194	[577]	[892,791,1195,722]	7	hSpCas9	negative selection	6739689
15945301	15945324	17	-	27260156	HCC44	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.3921901893681743	[163]	[309,152,351,195]	6	hSpCas9	negative selection	6739690
15975203	15975226	17	-	27260156	HCC44	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.2054431350181105	[202]	[182,138,297,198]	-3	hSpCas9	negative selection	6739691
15975319	15975342	17	-	27260156	HCC44	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	0.022249152162848257	[432]	[840,273,519,419]	0	hSpCas9	negative selection	6803971
15945541	15945564	17	-	27260156	HCC44	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.3234633862587868	[667]	[540,640,805,450]	-5	hSpCas9	negative selection	6803972
15945365	15945388	17	+	27260156	HCC44	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.28774459731446483	[617]	[767,722,1045,910]	5	hSpCas9	negative selection	6803973
15945296	15945319	17	+	27260156	G402	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.34716791630499594	[577]	[473,739,1172,1116]	4	hSpCas9	negative selection	6860940
15945301	15945324	17	-	27260156	G402	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.5081191581848712	[163]	[124,44,212,169]	-6	hSpCas9	negative selection	6860941
15975203	15975226	17	-	27260156	G402	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.12939496703952802	[202]	[110,237,231,466]	1	hSpCas9	negative selection	6860942
15975319	15975342	17	-	27260156	G402	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.3574454011001997	[432]	[465,310,590,287]	-4	hSpCas9	negative selection	6925222
15945541	15945564	17	-	27260156	G402	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.02515982847755527	[667]	[890,952,665,820]	0	hSpCas9	negative selection	6925223
15945365	15945388	17	+	27260156	G402	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.09923582765924444	[617]	[939,943,732,645]	1	hSpCas9	negative selection	6925224
15945296	15945319	17	+	27260156	L33	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.2500913017150554	[577]	[681,301,427,649]	5	hSpCas9	negative selection	6982191
15945301	15945324	17	-	27260156	L33	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.009062753654976552	[163]	[138,66,100,188]	0	hSpCas9	negative selection	6982192
15975203	15975226	17	-	27260156	L33	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.13561780483670782	[202]	[101,57,164,234]	-3	hSpCas9	negative selection	6982193
15975319	15975342	17	-	27260156	L33	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.254237114348977	[432]	[411,162,178,355]	-5	hSpCas9	negative selection	7046473
15945541	15945564	17	-	27260156	L33	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.2280282835207491	[667]	[552,181,351,722]	-5	hSpCas9	negative selection	7046474
15945365	15945388	17	+	27260156	L33	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.09056371346020686	[617]	[742,326,331,560]	2	hSpCas9	negative selection	7046475
15945296	15945319	17	+	27260156	K562	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.7908629734125734	[577]	[1131,855,770,813]	8	hSpCas9	negative selection	7103442
15945301	15945324	17	-	27260156	K562	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.22629461525712635	[163]	[117,160,126,258]	3	hSpCas9	negative selection	7103443
15975203	15975226	17	-	27260156	K562	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.19556850265238368	[202]	[258,98,286,180]	2	hSpCas9	negative selection	7103444
15975319	15975342	17	-	27260156	K562	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.4646978516437912	[432]	[356,301,255,212]	-5	hSpCas9	negative selection	7167724
15945541	15945564	17	-	27260156	K562	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.35840097933865656	[667]	[618,440,314,481]	-4	hSpCas9	negative selection	7167725
15945365	15945388	17	+	27260156	K562	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.5436550671101732	[617]	[890,1062,578,694]	7	hSpCas9	negative selection	7167726
15945296	15945319	17	+	27260156	HT29	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.5182838726548429	[577]	[958,971,1213,881]	8	hSpCas9	negative selection	7224693
15945301	15945324	17	-	27260156	HT29	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.08482530562859991	[163]	[178,311,144,213]	1	hSpCas9	negative selection	7224694
15975203	15975226	17	-	27260156	HT29	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.17060951154170323	[202]	[259,302,315,235]	3	hSpCas9	negative selection	7224695
15975319	15975342	17	-	27260156	HT29	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.24225868434018988	[432]	[324,658,375,427]	-5	hSpCas9	negative selection	7288975
15945541	15945564	17	-	27260156	HT29	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.018816586506842314	[667]	[692,981,727,803]	0	hSpCas9	negative selection	7288976
15945365	15945388	17	+	27260156	HT29	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.17593028478250056	[617]	[931,698,820,920]	3	hSpCas9	negative selection	7288977
15945296	15945319	17	+	27260156	MHHES1	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.6673663222647417	[577]	[1123,1039,933,1025]	9	hSpCas9	negative selection	7345944
15945301	15945324	17	-	27260156	MHHES1	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.25385210551911475	[163]	[194,107,187,130]	-5	hSpCas9	negative selection	7345945
15975203	15975226	17	-	27260156	MHHES1	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.06819411330679492	[202]	[428,169,284,114]	1	hSpCas9	negative selection	7345946
15975319	15975342	17	-	27260156	MHHES1	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.5058808750000429	[432]	[523,406,322,178]	-7	hSpCas9	negative selection	7410226
15945541	15945564	17	-	27260156	MHHES1	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.05345888940903232	[667]	[703,897,946,601]	1	hSpCas9	negative selection	7410227
15945365	15945388	17	+	27260156	MHHES1	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.30659544110843534	[617]	[917,1090,871,627]	5	hSpCas9	negative selection	7410228
15945296	15945319	17	+	27260156	MEWO	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.4741129169024611	[577]	[729,784,733]	8	hSpCas9	negative selection	7467195
15945301	15945324	17	-	27260156	MEWO	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.3769640061985171	[163]	[236,201,165]	7	hSpCas9	negative selection	7467196
15975203	15975226	17	-	27260156	MEWO	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.2714352777339949	[202]	[229,187,269]	6	hSpCas9	negative selection	7467197
15975319	15975342	17	-	27260156	MEWO	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.4905819835835985	[432]	[426,241,222]	-8	hSpCas9	negative selection	7531477
15945541	15945564	17	-	27260156	MEWO	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.06124918976381927	[667]	[655,567,583]	-1	hSpCas9	negative selection	7531478
15945365	15945388	17	+	27260156	MEWO	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.2613411528604653	[617]	[705,766,607]	5	hSpCas9	negative selection	7531479
15945296	15945319	17	+	27260156	LNCAPCLONEFGC	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.4135484732748674	[577]	[566,789,693,733]	6	hSpCas9	negative selection	7588446
15945301	15945324	17	-	27260156	LNCAPCLONEFGC	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.4567639241383894	[163]	[210,234,235,135]	7	hSpCas9	negative selection	7588447
15975203	15975226	17	-	27260156	LNCAPCLONEFGC	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.1344898182420371	[202]	[165,204,290,158]	2	hSpCas9	negative selection	7588448
15975319	15975342	17	-	27260156	LNCAPCLONEFGC	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.2352315846171969	[432]	[308,324,422,289]	-4	hSpCas9	negative selection	7652728
15945541	15945564	17	-	27260156	LNCAPCLONEFGC	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.2593961195691702	[667]	[404,492,622,520]	-4	hSpCas9	negative selection	7652729
15945365	15945388	17	+	27260156	LNCAPCLONEFGC	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.1954074033279149	[617]	[577,700,789,513]	3	hSpCas9	negative selection	7652730
15945296	15945319	17	+	27260156	PANC0327	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.578060940436568	[577]	[810,1099,515,598]	8	hSpCas9	negative selection	7709697
15945301	15945324	17	-	27260156	PANC0327	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.17909063477068798	[163]	[152,87,173,106]	-3	hSpCas9	negative selection	7709698
15975203	15975226	17	-	27260156	PANC0327	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.08385526306515922	[202]	[157,242,181,171]	1	hSpCas9	negative selection	7709699
15975319	15975342	17	-	27260156	PANC0327	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.5545701988235139	[432]	[79,350,263,325]	-7	hSpCas9	negative selection	7773979
15945541	15945564	17	-	27260156	PANC0327	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.3906273941568318	[667]	[779,261,486,332]	-5	hSpCas9	negative selection	7773980
15945365	15945388	17	+	27260156	PANC0327	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.18043030797591159	[617]	[668,481,576,781]	2	hSpCas9	negative selection	7773981
15945296	15945319	17	+	27260156	NCIH2009	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.7133443906177055	[577]	[1555,1092,1370]	8	hSpCas9	negative selection	7830948
15945301	15945324	17	-	27260156	NCIH2009	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.6644030492038563	[163]	[373,362,353]	8	hSpCas9	negative selection	7830949
15975203	15975226	17	-	27260156	NCIH2009	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.3814159055852413	[202]	[249,173,235]	-5	hSpCas9	negative selection	7830950
15975319	15975342	17	-	27260156	NCIH2009	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.3847919360407599	[432]	[513,586,295]	-5	hSpCas9	negative selection	7895230
15945541	15945564	17	-	27260156	NCIH2009	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.3019249043894441	[667]	[1052,1009,1369]	4	hSpCas9	negative selection	7895231
15945365	15945388	17	+	27260156	NCIH2009	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.40999254635864607	[617]	[1361,1048,1072]	5	hSpCas9	negative selection	7895232
15945296	15945319	17	+	27260156	NCIH1373	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	-0.10595038829574557	[577]	[689,615,346,204]	-1	hSpCas9	negative selection	7952199
15945301	15945324	17	-	27260156	NCIH1373	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.17589952199654357	[163]	[165,92,391,46]	1	hSpCas9	negative selection	7952200
15975203	15975226	17	-	27260156	NCIH1373	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.723839739260294	[202]	[117,193,50,47]	-6	hSpCas9	negative selection	7952201
15975319	15975342	17	-	27260156	NCIH1373	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.272359478639202	[432]	[446,561,256,85]	-3	hSpCas9	negative selection	8016481
15945541	15945564	17	-	27260156	NCIH1373	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.7487999437575563	[667]	[601,402,454,89]	-6	hSpCas9	negative selection	8016482
15945365	15945388	17	+	27260156	NCIH1373	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.2601080301140409	[617]	[792,786,561,314]	2	hSpCas9	negative selection	8016483
15945296	15945319	17	+	27260156	PATU8902	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.5645070562614314	[577]	[956,1231,1270,1285]	6	hSpCas9	negative selection	8073450
15945301	15945324	17	-	27260156	PATU8902	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.23481417021931184	[163]	[142,472,239,220]	2	hSpCas9	negative selection	8073451
15975203	15975226	17	-	27260156	PATU8902	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	1.2640865384301778	[202]	[693,471,838,660]	9	hSpCas9	negative selection	8073452
15975319	15975342	17	-	27260156	PATU8902	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-1.3365206938684313	[432]	[194,320,142,330]	-8	hSpCas9	negative selection	8137732
15945541	15945564	17	-	27260156	PATU8902	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.02655043337065177	[667]	[582,1110,942,1018]	0	hSpCas9	negative selection	8137733
15945365	15945388	17	+	27260156	PATU8902	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.3369101394038973	[617]	[1019,1061,884,1471]	3	hSpCas9	negative selection	8137734
15945296	15945319	17	+	27260156	PANC1	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.4481448548547297	[577]	[567,757,838,570]	7	hSpCas9	negative selection	8194701
15945301	15945324	17	-	27260156	PANC1	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.19910441963674264	[163]	[108,223,261,77]	3	hSpCas9	negative selection	8194702
15975203	15975226	17	-	27260156	PANC1	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.7230781030195317	[202]	[78,70,167,97]	-8	hSpCas9	negative selection	8194703
15975319	15975342	17	-	27260156	PANC1	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.7791373065698356	[432]	[190,285,198,203]	-8	hSpCas9	negative selection	8258983
15945541	15945564	17	-	27260156	PANC1	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.18822185758001153	[667]	[525,543,524,430]	-3	hSpCas9	negative selection	8258984
15945365	15945388	17	+	27260156	PANC1	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	-0.009989412786409024	[617]	[532,709,538,379]	0	hSpCas9	negative selection	8258985
15945296	15945319	17	+	27260156	PANC0813	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.3941837409165683	[577]	[967,835,765,997]	6	hSpCas9	negative selection	8315952
15945301	15945324	17	-	27260156	PANC0813	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.8516935817707092	[163]	[362,362,295,367]	9	hSpCas9	negative selection	8315953
15975203	15975226	17	-	27260156	PANC0813	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.4658070278264983	[202]	[193,174,129,191]	-6	hSpCas9	negative selection	8315954
15975319	15975342	17	-	27260156	PANC0813	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.1612265098947776	[432]	[629,390,334,476]	-3	hSpCas9	negative selection	8380234
15945541	15945564	17	-	27260156	PANC0813	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.37344118492489553	[667]	[676,767,492,495]	-5	hSpCas9	negative selection	8380235
15945365	15945388	17	+	27260156	PANC0813	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.18347205500840907	[617]	[932,1001,721,657]	3	hSpCas9	negative selection	8380236
15945296	15945319	17	+	27260156	RDES	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.5127468838105174	[577]	[858,901,909,1143]	7	hSpCas9	negative selection	8437203
15945301	15945324	17	-	27260156	RDES	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.15835040087427932	[163]	[221,177,171,270]	2	hSpCas9	negative selection	8437204
15975203	15975226	17	-	27260156	RDES	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.0235517126606255	[202]	[281,201,217,229]	0	hSpCas9	negative selection	8437205
15975319	15975342	17	-	27260156	RDES	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.3225791631293321	[432]	[307,377,274,679]	-5	hSpCas9	negative selection	8501485
15945541	15945564	17	-	27260156	RDES	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.11591569124715156	[667]	[476,640,893,896]	-2	hSpCas9	negative selection	8501486
15945365	15945388	17	+	27260156	RDES	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.0828834471737302	[617]	[688,626,843,874]	1	hSpCas9	negative selection	8501487
15945296	15945319	17	+	27260156	PC3	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.2732840489458987	[577]	[386,754,1318,634]	6	hSpCas9	negative selection	8558454
15945301	15945324	17	-	27260156	PC3	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.16405892853454684	[163]	[55,186,111,246]	-4	hSpCas9	negative selection	8558455
15975203	15975226	17	-	27260156	PC3	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.057953914559580655	[202]	[109,330,273,168]	1	hSpCas9	negative selection	8558456
15975319	15975342	17	-	27260156	PC3	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.31410158667395355	[432]	[210,350,550,382]	-6	hSpCas9	negative selection	8622736
15945541	15945564	17	-	27260156	PC3	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.178416495773354	[667]	[354,562,1002,644]	-4	hSpCas9	negative selection	8622737
15945365	15945388	17	+	27260156	PC3	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	-0.015531236202552978	[617]	[389,568,1154,572]	0	hSpCas9	negative selection	8622738
15945296	15945319	17	+	27260156	PATU8988T	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.340312532138443	[577]	[590,728,762,749]	6	hSpCas9	negative selection	8679705
15945301	15945324	17	-	27260156	PATU8988T	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.1877709012598825	[163]	[230,127,246,103]	3	hSpCas9	negative selection	8679706
15975203	15975226	17	-	27260156	PATU8988T	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.023813424188299237	[202]	[153,198,263,177]	0	hSpCas9	negative selection	8679707
15975319	15975342	17	-	27260156	PATU8988T	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.32279305645294704	[432]	[344,259,373,352]	-5	hSpCas9	negative selection	8743987
15945541	15945564	17	-	27260156	PATU8988T	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.05239790231719199	[667]	[461,665,537,846]	-1	hSpCas9	negative selection	8743988
15945365	15945388	17	+	27260156	PATU8988T	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.0897677573121175	[617]	[677,819,614,429]	1	hSpCas9	negative selection	8743989
15945296	15945319	17	+	27260156	T47D	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.6168615890908082	[577]	[1160,900,923,1161]	9	hSpCas9	negative selection	8800956
15945301	15945324	17	-	27260156	T47D	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.09539592819081322	[163]	[212,223,197,178]	2	hSpCas9	negative selection	8800957
15975203	15975226	17	-	27260156	T47D	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.16366254812715253	[202]	[305,207,291,257]	3	hSpCas9	negative selection	8800958
15975319	15975342	17	-	27260156	T47D	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.2813179040961978	[432]	[455,414,373,415]	-6	hSpCas9	negative selection	8865238
15945541	15945564	17	-	27260156	T47D	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.014128071998432024	[667]	[749,616,967,756]	0	hSpCas9	negative selection	8865239
15945365	15945388	17	+	27260156	T47D	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.3125895371906127	[617]	[808,833,956,982]	6	hSpCas9	negative selection	8865240
15945296	15945319	17	+	27260156	SU8686	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.6591621748354446	[577]	[838,762,973,1095]	9	hSpCas9	negative selection	8922207
15945301	15945324	17	-	27260156	SU8686	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.7805817318145266	[163]	[199,190,346,422]	9	hSpCas9	negative selection	8922208
15975203	15975226	17	-	27260156	SU8686	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	-0.08355670629735745	[202]	[101,223,184,264]	-1	hSpCas9	negative selection	8922209
15975319	15975342	17	-	27260156	SU8686	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.04810903278411878	[432]	[410,324,452,494]	-1	hSpCas9	negative selection	8986489
15945541	15945564	17	-	27260156	SU8686	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.11621801211900873	[667]	[662,474,972,815]	2	hSpCas9	negative selection	8986490
15945365	15945388	17	+	27260156	SU8686	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.23038305214795712	[617]	[670,594,835,806]	4	hSpCas9	negative selection	8986491
15945296	15945319	17	+	27260156	SKES1	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.48679077255085573	[577]	[754,967,907,624]	8	hSpCas9	negative selection	9043458
15945301	15945324	17	-	27260156	SKES1	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.16112741094937744	[163]	[214,102,120,148]	-4	hSpCas9	negative selection	9043459
15975203	15975226	17	-	27260156	SKES1	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.28462880444680483	[202]	[221,334,208,227]	6	hSpCas9	negative selection	9043460
15975319	15975342	17	-	27260156	SKES1	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.5412148288632705	[432]	[407,212,346,228]	-8	hSpCas9	negative selection	9107740
15945541	15945564	17	-	27260156	SKES1	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.3179010621009065	[667]	[573,622,623,348]	-6	hSpCas9	negative selection	9107741
15945365	15945388	17	+	27260156	SKES1	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.3335168387775124	[617]	[719,861,786,736]	7	hSpCas9	negative selection	9107742
15945296	15945319	17	+	27260156	TOV112D	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.4322641619902902	[577]	[726,998,581,861]	7	hSpCas9	negative selection	9164709
15945301	15945324	17	-	27260156	TOV112D	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.1844033920850332	[163]	[197,117,214,198]	3	hSpCas9	negative selection	9164710
15975203	15975226	17	-	27260156	TOV112D	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.5512065824104155	[202]	[324,236,228,384]	8	hSpCas9	negative selection	9164711
15975319	15975342	17	-	27260156	TOV112D	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.25469061139106974	[432]	[411,224,409,375]	-5	hSpCas9	negative selection	9228991
15945541	15945564	17	-	27260156	TOV112D	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.22446099018684396	[667]	[465,660,661,514]	-4	hSpCas9	negative selection	9228992
15945365	15945388	17	+	27260156	TOV112D	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.017649631906821006	[617]	[495,810,545,684]	0	hSpCas9	negative selection	9228993
15945296	15945319	17	+	27260156	TC71	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.43886717133606873	[577]	[791,928,688,962]	8	hSpCas9	negative selection	9285960
15945301	15945324	17	-	27260156	TC71	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.19107621062846447	[163]	[99,163,184,167]	-5	hSpCas9	negative selection	9285961
15975203	15975226	17	-	27260156	TC71	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.09023445268041974	[202]	[202,250,279,188]	2	hSpCas9	negative selection	9285962
15975319	15975342	17	-	27260156	TC71	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.45495015636282876	[432]	[370,374,339,262]	-8	hSpCas9	negative selection	9350242
15945541	15945564	17	-	27260156	TC71	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	0.09789249991401872	[667]	[685,660,719,1016]	2	hSpCas9	negative selection	9350243
15945365	15945388	17	+	27260156	TC71	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.022229329463517578	[617]	[648,634,657,754]	0	hSpCas9	negative selection	9350244
15945296	15945319	17	+	27260156	TC32	viability	CATCGCCGCGCTTTCGGTGGCGG	ADORA2B	ENSG00000170425	0.661177725912653	[577]	[908,597,1102,911]	9	hSpCas9	negative selection	9407211
15945301	15945324	17	-	27260156	TC32	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.2596604210185942	[163]	[164,170,171,225]	4	hSpCas9	negative selection	9407212
15975203	15975226	17	-	27260156	TC32	viability	GTTCCGGTAAGCATAGACAATGG	ADORA2B	ENSG00000170425	0.3768838377520488	[202]	[173,306,281,200]	6	hSpCas9	negative selection	9407213
15975319	15975342	17	-	27260156	TC32	viability	CATAGGCCCACACCGAGAGCAGG	ADORA2B	ENSG00000170425	-0.7304058894315102	[432]	[233,129,339,329]	-9	hSpCas9	negative selection	9471493
15945541	15945564	17	-	27260156	TC32	viability	CAGGTATCTGTCGACTGCCACGG	ADORA2B	ENSG00000170425	-0.104567459107611	[667]	[520,610,689,484]	-2	hSpCas9	negative selection	9471494
15945365	15945388	17	+	27260156	TC32	viability	GACGCCCACCAACTACTTCCTGG	ADORA2B	ENSG00000170425	0.14490664131313163	[617]	[530,534,799,751]	2	hSpCas9	negative selection	9471495
15945482	15945505	17	-	27869803	HPAFII	viability after 27 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.7001463807882409	[469]	[192,117,NaN]	-5	hSpCas9	negative selection	9559245
15945524	15945547	17	+	27869803	HPAFII	viability after 27 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	-0.33523354124592997	[237]	[84,110,NaN]	-3	hSpCas9	negative selection	9559246
15974736	15974759	17	-	27869803	HPAFII	viability after 27 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.15506113433971308	[257]	[135,109,NaN]	-1	hSpCas9	negative selection	9559252
15974741	15974764	17	-	27869803	HPAFII	viability after 27 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.24389200515864773	[317]	[168,117,NaN]	-2	hSpCas9	negative selection	9559253
15975021	15975044	17	-	27869803	HPAFII	viability after 27 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	0.2190344073443785	[360]	[149,279,NaN]	1	hSpCas9	negative selection	9559254
15975074	15975097	17	-	27869803	HPAFII	viability after 27 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.7345818180340651	[317]	[323,239,NaN]	6	hSpCas9	negative selection	9559255
15945482	15945505	17	-	27869803	HPAFII	viability after 15 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-1.029845176825598	[469]	[321,200,NaN]	-8	hSpCas9	negative selection	9641694
15945524	15945547	17	+	27869803	HPAFII	viability after 15 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.23696849754998722	[237]	[269,320,NaN]	2	hSpCas9	negative selection	9641695
15974736	15974759	17	-	27869803	HPAFII	viability after 15 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	0.375263137860295	[257]	[572,226,NaN]	4	hSpCas9	negative selection	9641701
15974741	15974764	17	-	27869803	HPAFII	viability after 15 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.17291793801171831	[317]	[415,232,NaN]	-2	hSpCas9	negative selection	9641702
15975021	15975044	17	-	27869803	HPAFII	viability after 15 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-0.5124882984509119	[360]	[205,312,NaN]	-5	hSpCas9	negative selection	9641703
15975074	15975097	17	-	27869803	HPAFII	viability after 15 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.41121755353330564	[317]	[599,363,NaN]	5	hSpCas9	negative selection	9641704
15945482	15945505	17	-	27869803	ASPC1	viability after 36 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	0.42591713607606474	[1161]	[987,72,602]	4	hSpCas9	negative selection	9724143
15945524	15945547	17	+	27869803	ASPC1	viability after 36 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.23957743069278903	[894]	[572,229,331]	2	hSpCas9	negative selection	9724144
15974736	15974759	17	-	27869803	ASPC1	viability after 36 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	0.19895835830196817	[513]	[166,224,215]	2	hSpCas9	negative selection	9724150
15974741	15974764	17	-	27869803	ASPC1	viability after 36 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.18721388797236588	[864]	[349,283,187]	-2	hSpCas9	negative selection	9724151
15975021	15975044	17	-	27869803	ASPC1	viability after 36 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-0.45134506536645597	[935]	[297,369,90]	-4	hSpCas9	negative selection	9724152
15975074	15975097	17	-	27869803	ASPC1	viability after 36 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.3655611955298232	[896]	[198,308,218]	-4	hSpCas9	negative selection	9724153
15945482	15945505	17	-	27869803	PATU8988S	viability after 35 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.2312747516731274	[1117]	[418,347,NaN]	-2	hSpCas9	negative selection	9806592
15945524	15945547	17	+	27869803	PATU8988S	viability after 35 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.7552971770328902	[746]	[435,579,NaN]	7	hSpCas9	negative selection	9806593
15974736	15974759	17	-	27869803	PATU8988S	viability after 35 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.3002212371515073	[548]	[209,148,NaN]	-3	hSpCas9	negative selection	9806599
15974741	15974764	17	-	27869803	PATU8988S	viability after 35 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.0038417742705210145	[699]	[357,203,NaN]	0	hSpCas9	negative selection	9806600
15975021	15975044	17	-	27869803	PATU8988S	viability after 35 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-1.2682598756485646	[651]	[116,100,NaN]	-8	hSpCas9	negative selection	9806601
15975074	15975097	17	-	27869803	PATU8988S	viability after 35 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.43998310409470376	[667]	[118,277,NaN]	-4	hSpCas9	negative selection	9806602
15945482	15945505	17	-	27869803	PATU8988S	viability after 31 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	0.13289130282401818	[1117]	[340,676,NaN]	1	hSpCas9	negative selection	9889041
15945524	15945547	17	+	27869803	PATU8988S	viability after 31 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.7726132087400688	[746]	[386,663,NaN]	8	hSpCas9	negative selection	9889042
15974736	15974759	17	-	27869803	PATU8988S	viability after 31 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.6321170411389325	[548]	[175,96,NaN]	-6	hSpCas9	negative selection	9889048
15974741	15974764	17	-	27869803	PATU8988S	viability after 31 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.0889006030035433	[699]	[261,262,NaN]	-1	hSpCas9	negative selection	9889049
15975021	15975044	17	-	27869803	PATU8988S	viability after 31 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	-1.377096799171618	[651]	[151,33,NaN]	-8	hSpCas9	negative selection	9889050
15975074	15975097	17	-	27869803	PATU8988S	viability after 31 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	-0.5915735286752366	[667]	[185,164,NaN]	-6	hSpCas9	negative selection	9889051
15945482	15945505	17	-	27869803	HPAFII	viability after 35 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-0.6458257595941296	[469]	[176,123,NaN]	-4	hSpCas9	negative selection	9971490
15945524	15945547	17	+	27869803	HPAFII	viability after 35 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	-0.13854115218886348	[237]	[76,145,NaN]	-1	hSpCas9	negative selection	9971491
15974736	15974759	17	-	27869803	HPAFII	viability after 35 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	0.005676568024028945	[257]	[148,110,NaN]	0	hSpCas9	negative selection	9971497
15974741	15974764	17	-	27869803	HPAFII	viability after 35 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.7869831144906345	[317]	[105,78,NaN]	-4	hSpCas9	negative selection	9971498
15975021	15975044	17	-	27869803	HPAFII	viability after 35 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	0.8865898707964264	[360]	[208,482,NaN]	6	hSpCas9	negative selection	9971499
15975074	15975097	17	-	27869803	HPAFII	viability after 35 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.22297526205963308	[317]	[209,162,NaN]	1	hSpCas9	negative selection	9971500
15945482	15945505	17	-	27869803	HPAFII	viability after 31 days	GCACGAAGCAGGCGAGGAAGAGG	ADORA2B	ENSG00000170425	-1.7875101383108936	[469]	[118,29,NaN]	-7	hSpCas9	negative selection	10053939
15945524	15945547	17	+	27869803	HPAFII	viability after 31 days	CATCTTCAGCCTTCTGGCCGTGG	ADORA2B	ENSG00000170425	0.3322809685136078	[237]	[48,297,NaN]	2	hSpCas9	negative selection	10053940
15974736	15974759	17	-	27869803	HPAFII	viability after 31 days	TCAATCCGATGCCAAAGGCAAGG	ADORA2B	ENSG00000170425	-0.056544565500647244	[257]	[121,157,NaN]	0	hSpCas9	negative selection	10053946
15974741	15974764	17	-	27869803	HPAFII	viability after 31 days	TGGAGTCAATCCGATGCCAAAGG	ADORA2B	ENSG00000170425	-0.7834384310747295	[317]	[118,86,NaN]	-5	hSpCas9	negative selection	10053947
15975021	15975044	17	-	27869803	HPAFII	viability after 31 days	TGGCTGCATGGATCTCCCGCTGG	ADORA2B	ENSG00000170425	0.7626721186840508	[360]	[281,410,NaN]	5	hSpCas9	negative selection	10053948
15975074	15975097	17	-	27869803	HPAFII	viability after 31 days	ATGCACAGGTAACCAGCACAGGG	ADORA2B	ENSG00000170425	0.280946831906375	[317]	[268,159,NaN]	2	hSpCas9	negative selection	10053949
15945301	15945324	17	-	28162770	P31FUJ	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.026348766932187018	[309]	[370]	0	hSpCas9	negative selection	10107618
15945293	15945316	17	+	28162770	P31FUJ	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	-0.7101239819475651	[141]	[101]	-5	hSpCas9	negative selection	10107619
15945439	15945462	17	-	28162770	P31FUJ	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.2266294142229186	[255]	[351]	2	hSpCas9	negative selection	10107620
15945337	15945360	17	-	28162770	P31FUJ	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.15422091869486854	[272]	[356]	1	hSpCas9	negative selection	10107621
15945403	15945426	17	-	28162770	P31FUJ	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	-0.14399293745652275	[62]	[66]	-1	hSpCas9	negative selection	10107622
15945560	15945583	17	-	28162770	P31FUJ	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.7487408908780604	[117]	[232]	8	hSpCas9	negative selection	10107623
15945266	15945289	17	+	28162770	P31FUJ	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	0.3741866026367766	[64]	[98]	4	hSpCas9	negative selection	10107624
15945320	15945343	17	+	28162770	P31FUJ	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.5925192641726744	[170]	[302]	6	hSpCas9	negative selection	10107625
15945370	15945393	17	-	28162770	P31FUJ	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.5142876070255348	[425]	[714]	6	hSpCas9	negative selection	10107626
15945488	15945511	17	-	28162770	P31FUJ	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.49272849468954427	[227]	[376]	5	hSpCas9	negative selection	10107627
15945301	15945324	17	-	28162770	TF1	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[313]	1	hSpCas9	negative selection	10276984
15945293	15945316	17	+	28162770	TF1	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[106]	1	hSpCas9	negative selection	10276985
15945439	15945462	17	-	28162770	TF1	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[334]	1	hSpCas9	negative selection	10276986
15945337	15945360	17	-	28162770	TF1	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[314]	1	hSpCas9	negative selection	10276987
15945403	15945426	17	-	28162770	TF1	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[69]	1	hSpCas9	negative selection	10276988
15945560	15945583	17	-	28162770	TF1	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10276989
15945266	15945289	17	+	28162770	TF1	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10276990
15945320	15945343	17	+	28162770	TF1	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10276991
15945370	15945393	17	-	28162770	TF1	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[480]	1	hSpCas9	negative selection	10276992
15945488	15945511	17	-	28162770	TF1	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10276993
15945301	15945324	17	-	28162770	SKM1	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	1.6760251659278698	[56]	[321]	9	hSpCas9	negative selection	10446350
15945293	15945316	17	+	28162770	SKM1	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	0.2711077063694761	[29]	[63]	2	hSpCas9	negative selection	10446351
15945439	15945462	17	-	28162770	SKM1	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	1.0950368529625958	[84]	[320]	8	hSpCas9	negative selection	10446352
15945337	15945360	17	-	28162770	SKM1	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.7236478786743246	[61]	[180]	7	hSpCas9	negative selection	10446353
15945403	15945426	17	-	28162770	SKM1	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	-0.6844981742720707	[29]	[32]	-5	hSpCas9	negative selection	10446354
15945560	15945583	17	-	28162770	SKM1	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	-0.09662407813101098	[74]	[123]	-1	hSpCas9	negative selection	10446355
15945266	15945289	17	+	28162770	SKM1	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	0.9731785100894964	[16]	[58]	8	hSpCas9	negative selection	10446356
15945320	15945343	17	+	28162770	SKM1	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.7832807870787466	[46]	[142]	7	hSpCas9	negative selection	10446357
15945370	15945393	17	-	28162770	SKM1	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.2522920843253085	[122]	[258]	2	hSpCas9	negative selection	10446358
15945488	15945511	17	-	28162770	SKM1	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	1.4082959213997885	[38]	[182]	9	hSpCas9	negative selection	10446359
15945301	15945324	17	-	28162770	SKM1	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	1.6760251659278698	[56]	[321]	9	hSpCas9	negative selection	10615716
15945293	15945316	17	+	28162770	SKM1	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	0.2711077063694761	[29]	[63]	2	hSpCas9	negative selection	10615717
15945439	15945462	17	-	28162770	SKM1	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	1.0950368529625958	[84]	[320]	8	hSpCas9	negative selection	10615718
15945337	15945360	17	-	28162770	SKM1	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.7236478786743246	[61]	[180]	7	hSpCas9	negative selection	10615719
15945403	15945426	17	-	28162770	SKM1	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	-0.6844981742720707	[29]	[32]	-5	hSpCas9	negative selection	10615720
15945560	15945583	17	-	28162770	SKM1	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	-0.09662407813101098	[74]	[123]	-1	hSpCas9	negative selection	10615721
15945266	15945289	17	+	28162770	SKM1	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	0.9731785100894964	[16]	[58]	8	hSpCas9	negative selection	10615722
15945320	15945343	17	+	28162770	SKM1	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.7832807870787466	[46]	[142]	7	hSpCas9	negative selection	10615723
15945370	15945393	17	-	28162770	SKM1	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.2522920843253085	[122]	[258]	2	hSpCas9	negative selection	10615724
15945488	15945511	17	-	28162770	SKM1	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	1.4082959213997885	[38]	[182]	9	hSpCas9	negative selection	10615725
15945301	15945324	17	-	28162770	PL21	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.12970814369428013	[273]	[108]	-1	hSpCas9	negative selection	10785082
15945293	15945316	17	+	28162770	PL21	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	0.5552345733118819	[85]	[54]	5	hSpCas9	negative selection	10785083
15945439	15945462	17	-	28162770	PL21	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	1.431165784159572	[356]	[418]	9	hSpCas9	negative selection	10785084
15945337	15945360	17	-	28162770	PL21	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.9945554808394261	[255]	[221]	8	hSpCas9	negative selection	10785085
15945403	15945426	17	-	28162770	PL21	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	1.2540784216001237	[104]	[108]	8	hSpCas9	negative selection	10785086
15945560	15945583	17	-	28162770	PL21	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	1.086610668858906	[184]	[170]	8	hSpCas9	negative selection	10785087
15945266	15945289	17	+	28162770	PL21	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	-0.2737915738430923	[49]	[17]	-2	hSpCas9	negative selection	10785088
15945320	15945343	17	+	28162770	PL21	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	1.0025396546041596	[124]	[108]	8	hSpCas9	negative selection	10785089
15945370	15945393	17	-	28162770	PL21	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.7485049615469057	[345]	[252]	6	hSpCas9	negative selection	10785090
15945488	15945511	17	-	28162770	PL21	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.7306543311880997	[197]	[142]	6	hSpCas9	negative selection	10785091
15945301	15945324	17	-	28162770	P31FUJ	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.026348766932187018	[309]	[370]	0	hSpCas9	negative selection	10954448
15945293	15945316	17	+	28162770	P31FUJ	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	-0.7101239819475651	[141]	[101]	-5	hSpCas9	negative selection	10954449
15945439	15945462	17	-	28162770	P31FUJ	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.2266294142229186	[255]	[351]	2	hSpCas9	negative selection	10954450
15945337	15945360	17	-	28162770	P31FUJ	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.15422091869486854	[272]	[356]	1	hSpCas9	negative selection	10954451
15945403	15945426	17	-	28162770	P31FUJ	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	-0.14399293745652275	[62]	[66]	-1	hSpCas9	negative selection	10954452
15945560	15945583	17	-	28162770	P31FUJ	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.7487408908780604	[117]	[232]	8	hSpCas9	negative selection	10954453
15945266	15945289	17	+	28162770	P31FUJ	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	0.3741866026367766	[64]	[98]	4	hSpCas9	negative selection	10954454
15945320	15945343	17	+	28162770	P31FUJ	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.5925192641726744	[170]	[302]	6	hSpCas9	negative selection	10954455
15945370	15945393	17	-	28162770	P31FUJ	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.5142876070255348	[425]	[714]	6	hSpCas9	negative selection	10954456
15945488	15945511	17	-	28162770	P31FUJ	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.49272849468954427	[227]	[376]	5	hSpCas9	negative selection	10954457
15945301	15945324	17	-	28162770	OCIAML5	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.6870922402440343	[127]	[371]	6	hSpCas9	negative selection	11123814
15945293	15945316	17	+	28162770	OCIAML5	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	0.2963252690286742	[59]	[132]	2	hSpCas9	negative selection	11123815
15945439	15945462	17	-	28162770	OCIAML5	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	-0.017288953341020985	[133]	[238]	0	hSpCas9	negative selection	11123816
15945337	15945360	17	-	28162770	OCIAML5	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	-0.20436831479487813	[149]	[234]	-1	hSpCas9	negative selection	11123817
15945403	15945426	17	-	28162770	OCIAML5	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	0.01787288857162994	[57]	[105]	0	hSpCas9	negative selection	11123818
15945560	15945583	17	-	28162770	OCIAML5	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.02082151123266368	[82]	[151]	0	hSpCas9	negative selection	11123819
15945266	15945289	17	+	28162770	OCIAML5	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	-0.9009761713449435	[59]	[57]	-5	hSpCas9	negative selection	11123820
15945320	15945343	17	+	28162770	OCIAML5	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	1.8181811178021285	[51]	[330]	9	hSpCas9	negative selection	11123821
15945370	15945393	17	-	28162770	OCIAML5	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.6627998028692983	[245]	[702]	6	hSpCas9	negative selection	11123822
15945488	15945511	17	-	28162770	OCIAML5	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	1.7981873901088783	[71]	[451]	9	hSpCas9	negative selection	11123823
15945301	15945324	17	-	28162770	EOL1	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.3748137591603601	[444]	[303]	3	hSpCas9	negative selection	11293180
15945293	15945316	17	+	28162770	EOL1	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	-0.4037780945149785	[112]	[44]	-3	hSpCas9	negative selection	11293181
15945439	15945462	17	-	28162770	EOL1	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.5972364799862689	[536]	[427]	5	hSpCas9	negative selection	11293182
15945337	15945360	17	-	28162770	EOL1	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.15267656245612704	[501]	[293]	1	hSpCas9	negative selection	11293183
15945403	15945426	17	-	28162770	EOL1	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	0.9056887443192186	[153]	[151]	7	hSpCas9	negative selection	11293184
15945560	15945583	17	-	28162770	EOL1	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.032923932615326564	[281]	[151]	0	hSpCas9	negative selection	11293185
15945266	15945289	17	+	28162770	EOL1	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	-0.7055026186791595	[64]	[20]	-5	hSpCas9	negative selection	11293186
15945320	15945343	17	+	28162770	EOL1	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	-0.9334332235570378	[173]	[47]	-6	hSpCas9	negative selection	11293187
15945370	15945393	17	-	28162770	EOL1	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.13471567676052354	[490]	[283]	1	hSpCas9	negative selection	11293188
15945488	15945511	17	-	28162770	EOL1	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	-0.09499241482511067	[222]	[109]	0	hSpCas9	negative selection	11293189
15945301	15945324	17	-	28162770	MOLM13	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.6473903852282229	[316]	[358]	5	hSpCas9	negative selection	11462546
15945293	15945316	17	+	28162770	MOLM13	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	-0.9634499300633655	[177]	[65]	-5	hSpCas9	negative selection	11462547
15945439	15945462	17	-	28162770	MOLM13	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	1.096795229853332	[387]	[599]	8	hSpCas9	negative selection	11462548
15945337	15945360	17	-	28162770	MOLM13	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	1.1009933767570803	[333]	[517]	8	hSpCas9	negative selection	11462549
15945403	15945426	17	-	28162770	MOLM13	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	0.9567759107106875	[118]	[166]	7	hSpCas9	negative selection	11462550
15945560	15945583	17	-	28162770	MOLM13	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.8052475170015472	[185]	[234]	6	hSpCas9	negative selection	11462551
15945266	15945289	17	+	28162770	MOLM13	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	1.2253190782705004	[41]	[70]	8	hSpCas9	negative selection	11462552
15945320	15945343	17	+	28162770	MOLM13	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	-0.7934971714077328	[174]	[72]	-4	hSpCas9	negative selection	11462553
15945370	15945393	17	-	28162770	MOLM13	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.6942550773309757	[517]	[605]	5	hSpCas9	negative selection	11462554
15945488	15945511	17	-	28162770	MOLM13	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.19571432185431595	[284]	[235]	1	hSpCas9	negative selection	11462555
15945301	15945324	17	-	28162770	HEL	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	1.260813819970846	[401]	[616]	9	hSpCas9	negative selection	11631912
15945293	15945316	17	+	28162770	HEL	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	-0.009337864579335942	[131]	[83]	0	hSpCas9	negative selection	11631913
15945439	15945462	17	-	28162770	HEL	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.42861402664750947	[376]	[324]	3	hSpCas9	negative selection	11631914
15945337	15945360	17	-	28162770	HEL	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.9008069849408011	[290]	[347]	7	hSpCas9	negative selection	11631915
15945403	15945426	17	-	28162770	HEL	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	-0.08202630856032211	[156]	[94]	0	hSpCas9	negative selection	11631916
15945560	15945583	17	-	28162770	HEL	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	1.2876438731777955	[164]	[257]	9	hSpCas9	negative selection	11631917
15945266	15945289	17	+	28162770	HEL	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	1.104642936317175	[52]	[72]	8	hSpCas9	negative selection	11631918
15945320	15945343	17	+	28162770	HEL	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.9471795001588781	[165]	[204]	8	hSpCas9	negative selection	11631919
15945370	15945393	17	-	28162770	HEL	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.5881698894609336	[457]	[440]	5	hSpCas9	negative selection	11631920
15945488	15945511	17	-	28162770	HEL	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	-0.7089366062810575	[244]	[95]	-4	hSpCas9	negative selection	11631921
15945301	15945324	17	-	28162770	MV411	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	-0.19032002499615214	[255]	[188]	-1	hSpCas9	negative selection	11801278
15945293	15945316	17	+	28162770	MV411	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	0.5162543092105751	[82]	[99]	4	hSpCas9	negative selection	11801279
15945439	15945462	17	-	28162770	MV411	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.27491828720488254	[311]	[317]	2	hSpCas9	negative selection	11801280
15945337	15945360	17	-	28162770	MV411	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.10644745006014322	[289]	[262]	0	hSpCas9	negative selection	11801281
15945403	15945426	17	-	28162770	MV411	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	-0.3941084783047484	[116]	[74]	-3	hSpCas9	negative selection	11801282
15945560	15945583	17	-	28162770	MV411	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	1.0282690303206137	[148]	[255]	8	hSpCas9	negative selection	11801283
15945266	15945289	17	+	28162770	MV411	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	1.1219066686989163	[47]	[87]	8	hSpCas9	negative selection	11801284
15945320	15945343	17	+	28162770	MV411	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	1.4408664891307024	[114]	[262]	9	hSpCas9	negative selection	11801285
15945370	15945393	17	-	28162770	MV411	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.882153086701031	[303]	[471]	7	hSpCas9	negative selection	11801286
15945488	15945511	17	-	28162770	MV411	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.6529522759431127	[113]	[150]	6	hSpCas9	negative selection	11801287
15945301	15945324	17	-	28162770	MONOMAC1	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.39519365412564156	[131]	[198]	4	hSpCas9	negative selection	11970644
15945293	15945316	17	+	28162770	MONOMAC1	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	-0.35231507253746464	[48]	[43]	-3	hSpCas9	negative selection	11970645
15945439	15945462	17	-	28162770	MONOMAC1	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	-0.435196584254318	[229]	[194]	-4	hSpCas9	negative selection	11970646
15945337	15945360	17	-	28162770	MONOMAC1	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	0.6900690965345129	[185]	[343]	6	hSpCas9	negative selection	11970647
15945403	15945426	17	-	28162770	MONOMAC1	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	-0.1563948625622078	[69]	[71]	-1	hSpCas9	negative selection	11970648
15945560	15945583	17	-	28162770	MONOMAC1	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	1.5726655335186521	[121]	[415]	9	hSpCas9	negative selection	11970649
15945266	15945289	17	+	28162770	MONOMAC1	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	2.2742688718660355	[21]	[121]	9	hSpCas9	negative selection	11970650
15945320	15945343	17	+	28162770	MONOMAC1	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	-0.11550696156295537	[85]	[90]	-1	hSpCas9	negative selection	11970651
15945370	15945393	17	-	28162770	MONOMAC1	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	1.6259261793524933	[196]	[696]	9	hSpCas9	negative selection	11970652
15945488	15945511	17	-	28162770	MONOMAC1	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.9416694237720384	[108]	[239]	8	hSpCas9	negative selection	11970653
15945301	15945324	17	-	28162770	OCIAML2	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.8358682290755952	[46]	[464]	7	hSpCas9	negative selection	12140010
15945293	15945316	17	+	28162770	OCIAML2	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	0.8704070925929059	[14]	[151]	8	hSpCas9	negative selection	12140011
15945439	15945462	17	-	28162770	OCIAML2	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.8317454722238006	[51]	[512]	7	hSpCas9	negative selection	12140012
15945337	15945360	17	-	28162770	OCIAML2	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	1.2420882226773677	[35]	[471]	9	hSpCas9	negative selection	12140013
15945403	15945426	17	-	28162770	OCIAML2	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	0.22451559322941783	[20]	[135]	2	hSpCas9	negative selection	12140014
15945560	15945583	17	-	28162770	OCIAML2	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.6723281285998817	[23]	[211]	6	hSpCas9	negative selection	12140015
15945266	15945289	17	+	28162770	OCIAML2	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	0.19233518748026812	[11]	[75]	1	hSpCas9	negative selection	12140016
15945320	15945343	17	+	28162770	OCIAML2	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.1956327775808432	[22]	[145]	1	hSpCas9	negative selection	12140017
15945370	15945393	17	-	28162770	OCIAML2	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.7062479368419179	[45]	[415]	7	hSpCas9	negative selection	12140018
15945488	15945511	17	-	28162770	OCIAML2	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	-0.20592659904774874	[35]	[172]	-2	hSpCas9	negative selection	12140019
15945301	15945324	17	-	28162770	OCIAML3	viability	GTTGCCCGCCACCGAAAGCGCGG	ADORA2B	ENSG00000170425	0.6092759580645801	[75]	[349]	5	hSpCas9	negative selection	12309376
15945293	15945316	17	+	28162770	OCIAML3	viability	GGTCATCGCCGCGCTTTCGGTGG	ADORA2B	ENSG00000170425	0.8028825122444214	[29]	[157]	7	hSpCas9	negative selection	12309377
15945439	15945462	17	-	28162770	OCIAML3	viability	GAAGCCCAGGCTGATGGTGATGG	ADORA2B	ENSG00000170425	0.479454521616858	[66]	[281]	4	hSpCas9	negative selection	12309378
15945337	15945360	17	-	28162770	OCIAML3	viability	AGTGTTCGCCGTGCCCACCGCGG	ADORA2B	ENSG00000170425	-0.7481785704519233	[73]	[132]	-5	hSpCas9	negative selection	12309379
15945403	15945426	17	-	28162770	OCIAML3	viability	GAAGAGCCCCACGGCCACGTCGG	ADORA2B	ENSG00000170425	0.3914927899807217	[24]	[98]	3	hSpCas9	negative selection	12309380
15945560	15945583	17	-	28162770	OCIAML3	viability	TGAGCGGGACACAGATGGCCAGG	ADORA2B	ENSG00000170425	0.18177720273257125	[32]	[112]	1	hSpCas9	negative selection	12309381
15945266	15945289	17	+	28162770	OCIAML3	viability	GGACGCGCTGTACGTGGCGCTGG	ADORA2B	ENSG00000170425	-0.5065447990738239	[7]	[16]	-4	hSpCas9	negative selection	12309382
15945320	15945343	17	+	28162770	OCIAML3	viability	CAACGTGCTGGTGTGCGCCGCGG	ADORA2B	ENSG00000170425	0.6307792961526675	[42]	[200]	6	hSpCas9	negative selection	12309383
15945370	15945393	17	-	28162770	OCIAML3	viability	GGACACCAGGAAGTAGTTGGTGG	ADORA2B	ENSG00000170425	0.3014617762045302	[92]	[345]	3	hSpCas9	negative selection	12309384
15945488	15945511	17	-	28162770	OCIAML3	viability	GCACCAGCACGAAGCAGGCGAGG	ADORA2B	ENSG00000170425	0.5651909545250907	[44]	[200]	5	hSpCas9	negative selection	12309385