Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:148
• Symbol:ADRA1A
• Description:adrenoceptor alpha 1A

DataSource: http://genomecrispr.dkfz.de/#!/results/ADRA1A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
26864759	26864782	8	-	26472758	Jiyoye	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	-0.1239806755194891	[249]	[172]	-1	hSpCas9	negative selection	3419
26770318	26770341	8	+	26472758	Jiyoye	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.9754591410803992	[86]	[128]	6	hSpCas9	negative selection	3420
26864721	26864744	8	+	26472758	Jiyoye	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	2.051031571280598	[7]	[24]	8	hSpCas9	negative selection	3421
26864670	26864693	8	+	26472758	Jiyoye	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.4506146427707707	[228]	[235]	3	hSpCas9	negative selection	3422
26864600	26864623	8	+	26472758	Jiyoye	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	0.6649731389735203	[91]	[109]	5	hSpCas9	negative selection	3423
26864557	26864580	8	+	26472758	Jiyoye	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.847747972891855	[209]	[284]	6	hSpCas9	negative selection	3424
26864339	26864362	8	-	26472758	Jiyoye	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	1.1639042304935097	[28]	[48]	7	hSpCas9	negative selection	3425
26864320	26864343	8	-	26472758	Jiyoye	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-2.1018382659819843	[147]	[25]	-8	hSpCas9	negative selection	3426
26770481	26770504	8	-	26472758	Jiyoye	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	0.43632172716538986	[48]	[49]	3	hSpCas9	negative selection	3427
26770427	26770450	8	-	26472758	Jiyoye	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	-0.5157835827302986	[236]	[124]	-4	hSpCas9	negative selection	3428
26864759	26864782	8	-	26472758	KBM7	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.23247211511264515	[732,435]	[314,316]	2	hSpCas9	negative selection	194537
26770318	26770341	8	+	26472758	KBM7	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.1476980507204993	[634,563]	[228,385]	1	hSpCas9	negative selection	194538
26864721	26864744	8	+	26472758	KBM7	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-1.53855307850948	[118,52]	[23,3]	-8	hSpCas9	negative selection	194539
26864670	26864693	8	+	26472758	KBM7	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	-0.1828239027416938	[1063,535]	[400,250]	-2	hSpCas9	negative selection	194540
26864600	26864623	8	+	26472758	KBM7	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-0.6908442814434489	[325,235]	[110,53]	-5	hSpCas9	negative selection	194541
26864557	26864580	8	+	26472758	KBM7	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.5681073394178949	[1209,635]	[718,542]	6	hSpCas9	negative selection	194542
26864339	26864362	8	-	26472758	KBM7	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	0.03841215144140597	[506,489]	[345,147]	0	hSpCas9	negative selection	194543
26864320	26864343	8	-	26472758	KBM7	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-0.0208360242354918	[302,245]	[173,83]	0	hSpCas9	negative selection	194544
26770481	26770504	8	-	26472758	KBM7	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	-0.6164689392789384	[366,386]	[125,107]	-5	hSpCas9	negative selection	194545
26770427	26770450	8	-	26472758	KBM7	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.4961173353644539	[452,648]	[480,277]	5	hSpCas9	negative selection	194546
26864759	26864782	8	-	26472758	Raji	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.7992612400112676	[207]	[83]	7	hSpCas9	negative selection	385655
26770318	26770341	8	+	26472758	Raji	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.46470553679615584	[305]	[97]	4	hSpCas9	negative selection	385656
26864721	26864744	8	+	26472758	Raji	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-0.7406133711813507	[35]	[4]	-5	hSpCas9	negative selection	385657
26864670	26864693	8	+	26472758	Raji	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	-0.13153478305372723	[438]	[92]	-1	hSpCas9	negative selection	385658
26864600	26864623	8	+	26472758	Raji	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-0.19796167531815861	[172]	[34]	-2	hSpCas9	negative selection	385659
26864557	26864580	8	+	26472758	Raji	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.4444185226511701	[455]	[143]	4	hSpCas9	negative selection	385660
26864339	26864362	8	-	26472758	Raji	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-0.016445051479258843	[230]	[52]	0	hSpCas9	negative selection	385661
26864320	26864343	8	-	26472758	Raji	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	0.45968527930448055	[93]	[29]	4	hSpCas9	negative selection	385662
26770481	26770504	8	-	26472758	Raji	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	0.021807803667525494	[190]	[44]	0	hSpCas9	negative selection	385663
26770427	26770450	8	-	26472758	Raji	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	-0.9515101536799688	[324]	[38]	-6	hSpCas9	negative selection	385664
26864759	26864782	8	-	26472758	K562	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	-0.256934340403955	[418]	[295]	-2	hSpCas9	negative selection	576773
26770318	26770341	8	+	26472758	K562	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.2248785412708019	[445]	[439]	1	hSpCas9	negative selection	576774
26864721	26864744	8	+	26472758	K562	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-1.725207623290034	[93]	[23]	-7	hSpCas9	negative selection	576775
26864670	26864693	8	+	26472758	K562	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.8657616641141019	[495]	[762]	7	hSpCas9	negative selection	576776
26864600	26864623	8	+	26472758	K562	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	1.7826329691961238	[229]	[667]	9	hSpCas9	negative selection	576777
26864557	26864580	8	+	26472758	K562	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.07449372622413453	[737]	[655]	0	hSpCas9	negative selection	576778
26864339	26864362	8	-	26472758	K562	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	0.4757442737729025	[367]	[431]	4	hSpCas9	negative selection	576779
26864320	26864343	8	-	26472758	K562	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	0.040278010886221516	[143]	[124]	0	hSpCas9	negative selection	576780
26770481	26770504	8	-	26472758	K562	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	1.9639061065099874	[190]	[628]	9	hSpCas9	negative selection	576781
26770427	26770450	8	-	26472758	K562	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.4169815423775629	[424]	[478]	3	hSpCas9	negative selection	576782
26756734	26756757	8	+	26627737	DLD1	viability	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.5779727742198463	[371]	[160,178,179]	6	hSpCas9	negative selection	839199
26766058	26766081	8	+	26627737	DLD1	viability	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	-0.09433084787896664	[540]	[192,170,117]	-1	hSpCas9	negative selection	839200
26770397	26770420	8	+	26627737	DLD1	viability	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-1.1267412535619248	[329]	[36,50,52]	-7	hSpCas9	negative selection	839201
26859132	26859155	8	-	26627737	DLD1	viability	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.08217433856585799	[871]	[386,219,259]	0	hSpCas9	negative selection	839202
26864487	26864510	8	+	26627737	DLD1	viability	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.3217534607688459	[296]	[126,135,89]	3	hSpCas9	negative selection	839203
26864707	26864730	8	+	26627737	DLD1	viability	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.7313969548665991	[405]	[282,153,194]	7	hSpCas9	negative selection	839204
26756734	26756757	8	+	26627737	GBM cells	viability after 5 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.16740271081158759	[175]	[110,100]	2	hSpCas9	negative selection	921514
26766058	26766081	8	+	26627737	GBM cells	viability after 5 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.3998121108183672	[264]	[170,203]	6	hSpCas9	negative selection	921515
26770397	26770420	8	+	26627737	GBM cells	viability after 5 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.7860774441667426	[208]	[66,62]	-8	hSpCas9	negative selection	921516
26859132	26859155	8	-	26627737	GBM cells	viability after 5 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.6205110676286876	[301]	[259,237]	8	hSpCas9	negative selection	921517
26864487	26864510	8	+	26627737	GBM cells	viability after 5 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-0.358883882581961	[164]	[79,57]	-5	hSpCas9	negative selection	921518
26864707	26864730	8	+	26627737	GBM cells	viability after 5 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.6070246063797068	[302]	[215,278]	8	hSpCas9	negative selection	921519
26756734	26756757	8	+	26627737	GBM cells	viability after 13 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.4213448887181199	[175]	[171,91]	5	hSpCas9	negative selection	1003829
26766058	26766081	8	+	26627737	GBM cells	viability after 13 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.4540909855897016	[264]	[207,187]	6	hSpCas9	negative selection	1003830
26770397	26770420	8	+	26627737	GBM cells	viability after 13 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.005828254144256223	[208]	[134,94]	0	hSpCas9	negative selection	1003831
26859132	26859155	8	-	26627737	GBM cells	viability after 13 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.9161909526573607	[301]	[338,284]	9	hSpCas9	negative selection	1003832
26864487	26864510	8	+	26627737	GBM cells	viability after 13 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.03518590545644418	[164]	[115,71]	0	hSpCas9	negative selection	1003833
26864707	26864730	8	+	26627737	GBM cells	viability after 13 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.6439344094142536	[302]	[241,268]	7	hSpCas9	negative selection	1003834
26756734	26756757	8	+	26627737	GBM cells	viability after 21 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.28292240646685723	[175]	[131,101]	3	hSpCas9	negative selection	1086144
26766058	26766081	8	+	26627737	GBM cells	viability after 21 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.5763391275585577	[264]	[198,228]	6	hSpCas9	negative selection	1086145
26770397	26770420	8	+	26627737	GBM cells	viability after 21 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.04985224964548132	[208]	[116,102]	0	hSpCas9	negative selection	1086146
26859132	26859155	8	-	26627737	GBM cells	viability after 21 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.8240573625972286	[301]	[302,278]	7	hSpCas9	negative selection	1086147
26864487	26864510	8	+	26627737	GBM cells	viability after 21 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.5544139143290157	[164]	[139,123]	5	hSpCas9	negative selection	1086148
26864707	26864730	8	+	26627737	GBM cells	viability after 21 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.5784004216280071	[302]	[226,262]	6	hSpCas9	negative selection	1086149
26756734	26756757	8	+	26627737	RPE1	viability after 9 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	1.6616374879440663	[240]	[153,347]	8	hSpCas9	negative selection	1168459
26766058	26766081	8	+	26627737	RPE1	viability after 9 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	1.0654273885261585	[653]	[424,432]	6	hSpCas9	negative selection	1168460
26770397	26770420	8	+	26627737	RPE1	viability after 9 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.04612596359503107	[315]	[128,52]	0	hSpCas9	negative selection	1168461
26859132	26859155	8	-	26627737	RPE1	viability after 9 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.1816813748513113	[1634]	[425,779]	1	hSpCas9	negative selection	1168462
26864487	26864510	8	+	26627737	RPE1	viability after 9 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.23562476042748437	[343]	[121,132]	1	hSpCas9	negative selection	1168463
26864707	26864730	8	+	26627737	RPE1	viability after 9 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.5906019014357432	[1070]	[586,398]	4	hSpCas9	negative selection	1168464
26756734	26756757	8	+	26627737	RPE1	viability after 12 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	2.0493112659009487	[240]	[250,285]	9	hSpCas9	negative selection	1250774
26766058	26766081	8	+	26627737	RPE1	viability after 12 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	1.5949114884669977	[653]	[539,520]	8	hSpCas9	negative selection	1250775
26770397	26770420	8	+	26627737	RPE1	viability after 12 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.020267404139321377	[315]	[90,75]	0	hSpCas9	negative selection	1250776
26859132	26859155	8	-	26627737	RPE1	viability after 12 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	-0.4462555750717021	[1634]	[267,379]	-3	hSpCas9	negative selection	1250777
26864487	26864510	8	+	26627737	RPE1	viability after 12 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.4183807609219772	[343]	[106,140]	2	hSpCas9	negative selection	1250778
26864707	26864730	8	+	26627737	RPE1	viability after 12 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.8895150325296425	[1070]	[534,530]	5	hSpCas9	negative selection	1250779
26756734	26756757	8	+	26627737	RPE1	viability after 15 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	2.3357883287889005	[240]	[278,406]	9	hSpCas9	negative selection	1333089
26766058	26766081	8	+	26627737	RPE1	viability after 15 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	1.725872552388875	[653]	[445,771]	8	hSpCas9	negative selection	1333090
26770397	26770420	8	+	26627737	RPE1	viability after 15 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.41049671025618983	[315]	[52,80]	-3	hSpCas9	negative selection	1333091
26859132	26859155	8	-	26627737	RPE1	viability after 15 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	-0.15058922380805317	[1634]	[294,533]	-1	hSpCas9	negative selection	1333092
26864487	26864510	8	+	26627737	RPE1	viability after 15 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-0.09038647841037117	[343]	[96,85]	0	hSpCas9	negative selection	1333093
26864707	26864730	8	+	26627737	RPE1	viability after 15 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.49099532064253637	[1070]	[493,359]	3	hSpCas9	negative selection	1333094
26756734	26756757	8	+	26627737	RPE1	viability after 18 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	2.4576121871337877	[240]	[393,317]	9	hSpCas9	negative selection	1415404
26766058	26766081	8	+	26627737	RPE1	viability after 18 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	2.0458367862267917	[653]	[415,1062]	8	hSpCas9	negative selection	1415405
26770397	26770420	8	+	26627737	RPE1	viability after 18 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	0.24788506565612023	[315]	[108,92]	1	hSpCas9	negative selection	1415406
26859132	26859155	8	-	26627737	RPE1	viability after 18 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.18721250049977378	[1634]	[250,770]	1	hSpCas9	negative selection	1415407
26864487	26864510	8	+	26627737	RPE1	viability after 18 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.5876963551325946	[343]	[139,138]	3	hSpCas9	negative selection	1415408
26864707	26864730	8	+	26627737	RPE1	viability after 18 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.6781537386359563	[1070]	[417,509]	4	hSpCas9	negative selection	1415409
26756734	26756757	8	+	26627737	HeLa	viability after 8 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.16687416529132193	[265]	[157,122,115]	1	hSpCas9	negative selection	1497719
26766058	26766081	8	+	26627737	HeLa	viability after 8 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.9675437663954434	[217]	[132,256,156]	7	hSpCas9	negative selection	1497720
26770397	26770420	8	+	26627737	HeLa	viability after 8 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	1.5806408330914687	[133]	[260,265,25]	9	hSpCas9	negative selection	1497721
26859132	26859155	8	-	26627737	HeLa	viability after 8 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	-0.24002797415192767	[906]	[358,477,181]	-2	hSpCas9	negative selection	1497722
26864487	26864510	8	+	26627737	HeLa	viability after 8 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-0.32587209005449436	[332]	[144,132,77]	-3	hSpCas9	negative selection	1497723
26864707	26864730	8	+	26627737	HeLa	viability after 8 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	1.4867635292842911	[222]	[320,238,266]	9	hSpCas9	negative selection	1497724
26756734	26756757	8	+	26627737	HeLa	viability after 12 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.6542871917899503	[265]	[214,80,233]	5	hSpCas9	negative selection	1580034
26766058	26766081	8	+	26627737	HeLa	viability after 12 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	1.0773778573432464	[217]	[125,203,236]	7	hSpCas9	negative selection	1580035
26770397	26770420	8	+	26627737	HeLa	viability after 12 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	1.2755282347739771	[133]	[164,115,123]	8	hSpCas9	negative selection	1580036
26859132	26859155	8	-	26627737	HeLa	viability after 12 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	-0.480198122175865	[906]	[358,171,287]	-4	hSpCas9	negative selection	1580037
26864487	26864510	8	+	26627737	HeLa	viability after 12 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-0.8628012056642577	[332]	[15,134,67]	-7	hSpCas9	negative selection	1580038
26864707	26864730	8	+	26627737	HeLa	viability after 12 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	1.2047455431290877	[222]	[242,194,201]	8	hSpCas9	negative selection	1580039
26756734	26756757	8	+	26627737	HeLa	viability after 15 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.4472025068020452	[265]	[286,7,145]	4	hSpCas9	negative selection	1662349
26766058	26766081	8	+	26627737	HeLa	viability after 15 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.48544876570732376	[217]	[75,80,223]	4	hSpCas9	negative selection	1662350
26770397	26770420	8	+	26627737	HeLa	viability after 15 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	0.7692307775943548	[133]	[118,109,45]	6	hSpCas9	negative selection	1662351
26859132	26859155	8	-	26627737	HeLa	viability after 15 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	-0.24806379792044964	[906]	[341,210,384]	-2	hSpCas9	negative selection	1662352
26864487	26864510	8	+	26627737	HeLa	viability after 15 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-0.9647837393703332	[332]	[29,107,70]	-7	hSpCas9	negative selection	1662353
26864707	26864730	8	+	26627737	HeLa	viability after 15 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	1.1802385295260902	[222]	[236,255,116]	8	hSpCas9	negative selection	1662354
26756734	26756757	8	+	26627737	HeLa	viability after 18 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.5069006940903309	[265]	[205,4,145]	4	hSpCas9	negative selection	1744664
26766058	26766081	8	+	26627737	HeLa	viability after 18 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.49348730597057155	[217]	[53,64,223]	4	hSpCas9	negative selection	1744665
26770397	26770420	8	+	26627737	HeLa	viability after 18 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	0.7967949630920671	[133]	[80,93,45]	6	hSpCas9	negative selection	1744666
26859132	26859155	8	-	26627737	HeLa	viability after 18 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	-0.2809789461984147	[906]	[213,176,384]	-2	hSpCas9	negative selection	1744667
26864487	26864510	8	+	26627737	HeLa	viability after 18 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-0.8885658999247753	[332]	[22,94,70]	-7	hSpCas9	negative selection	1744668
26864707	26864730	8	+	26627737	HeLa	viability after 18 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	1.2031326163348224	[222]	[166,209,116]	8	hSpCas9	negative selection	1744669
26756734	26756757	8	+	26627737	HCT116	viability after 6 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.45664483935417755	[137]	[61,11]	2	hSpCas9	negative selection	1826979
26766058	26766081	8	+	26627737	HCT116	viability after 6 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.6286461802458293	[321]	[85,73]	3	hSpCas9	negative selection	1826980
26770397	26770420	8	+	26627737	HCT116	viability after 6 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.21578857646154836	[175]	[8,31]	-1	hSpCas9	negative selection	1826981
26859132	26859155	8	-	26627737	HCT116	viability after 6 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	-1.246021675766213	[1273]	[106,71]	-6	hSpCas9	negative selection	1826982
26864487	26864510	8	+	26627737	HCT116	viability after 6 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.6540671817897453	[384]	[247,10]	3	hSpCas9	negative selection	1826983
26864707	26864730	8	+	26627737	HCT116	viability after 6 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	1.1136710865217345	[399]	[215,91]	6	hSpCas9	negative selection	1826984
26756734	26756757	8	+	26627737	HCT116	viability after 8 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	-0.4432562809915741	[186]	[73,50,101]	-5	hSpCas9	negative selection	1909294
26766058	26766081	8	+	26627737	HCT116	viability after 8 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.006307890300112279	[315]	[241,202,81]	0	hSpCas9	negative selection	1909295
26770397	26770420	8	+	26627737	HCT116	viability after 8 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	0.12358274175290063	[240]	[122,195,114]	1	hSpCas9	negative selection	1909296
26859132	26859155	8	-	26627737	HCT116	viability after 8 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.9119477996266596	[387]	[438,407,360]	8	hSpCas9	negative selection	1909297
26864487	26864510	8	+	26627737	HCT116	viability after 8 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.7532876404028144	[98]	[96,90,87]	7	hSpCas9	negative selection	1909298
26864707	26864730	8	+	26627737	HCT116	viability after 8 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.9749338668653715	[214]	[240,164,291]	8	hSpCas9	negative selection	1909299
26756734	26756757	8	+	26627737	HCT116	viability after 9 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	-0.48471639796875365	[137]	[46,9]	-3	hSpCas9	negative selection	1991609
26766058	26766081	8	+	26627737	HCT116	viability after 9 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	1.821957691928455	[321]	[160,416]	9	hSpCas9	negative selection	1991610
26770397	26770420	8	+	26627737	HCT116	viability after 9 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	1.7038801759158853	[175]	[299,36]	9	hSpCas9	negative selection	1991611
26859132	26859155	8	-	26627737	HCT116	viability after 9 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	-0.09617367714427394	[1273]	[334,304]	0	hSpCas9	negative selection	1991612
26864487	26864510	8	+	26627737	HCT116	viability after 9 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-0.43221042728732306	[384]	[164,5]	-3	hSpCas9	negative selection	1991613
26864707	26864730	8	+	26627737	HCT116	viability after 9 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	1.592454084623648	[399]	[139,465]	8	hSpCas9	negative selection	1991614
26756734	26756757	8	+	26627737	HCT116	viability after 12 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	-0.40742800219808206	[186]	[81,90,48]	-4	hSpCas9	negative selection	2073924
26766058	26766081	8	+	26627737	HCT116	viability after 12 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.5965287305301568	[315]	[272,234,242]	5	hSpCas9	negative selection	2073925
26770397	26770420	8	+	26627737	HCT116	viability after 12 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	0.054378118293339495	[240]	[175,104,108]	0	hSpCas9	negative selection	2073926
26859132	26859155	8	-	26627737	HCT116	viability after 12 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.5925071748700332	[387]	[376,254,282]	5	hSpCas9	negative selection	2073927
26864487	26864510	8	+	26627737	HCT116	viability after 12 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	1.0505104220653945	[98]	[94,90,137]	8	hSpCas9	negative selection	2073928
26864707	26864730	8	+	26627737	HCT116	viability after 12 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.4984092085417939	[214]	[156,197,124]	5	hSpCas9	negative selection	2073929
26756734	26756757	8	+	26627737	HCT116	viability after 15 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.21560472851797363	[186]	[115,210,46]	2	hSpCas9	negative selection	2156239
26766058	26766081	8	+	26627737	HCT116	viability after 15 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	-0.26210695041818477	[315]	[140,182,128]	-3	hSpCas9	negative selection	2156240
26770397	26770420	8	+	26627737	HCT116	viability after 15 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	0.6623424540296012	[240]	[269,145,246]	6	hSpCas9	negative selection	2156241
26859132	26859155	8	-	26627737	HCT116	viability after 15 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.7261343954203969	[387]	[419,318,372]	6	hSpCas9	negative selection	2156242
26864487	26864510	8	+	26627737	HCT116	viability after 15 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.9957077382895714	[98]	[79,54,199]	8	hSpCas9	negative selection	2156243
26864707	26864730	8	+	26627737	HCT116	viability after 15 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.827061582218231	[214]	[213,178,262]	7	hSpCas9	negative selection	2156244
26756734	26756757	8	+	26627737	HCT116	viability after 18 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.11068253628805158	[186]	[37,154,95]	1	hSpCas9	negative selection	2238554
26766058	26766081	8	+	26627737	HCT116	viability after 18 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	-0.1322116639696736	[315]	[116,132,169]	-1	hSpCas9	negative selection	2238555
26770397	26770420	8	+	26627737	HCT116	viability after 18 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	0.102401496851598	[240]	[173,89,112]	0	hSpCas9	negative selection	2238556
26859132	26859155	8	-	26627737	HCT116	viability after 18 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.4457833778921792	[387]	[335,217,212]	4	hSpCas9	negative selection	2238557
26864487	26864510	8	+	26627737	HCT116	viability after 18 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.977863763582397	[98]	[55,73,156]	7	hSpCas9	negative selection	2238558
26864707	26864730	8	+	26627737	HCT116	viability after 18 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.5550305942316566	[214]	[133,152,171]	4	hSpCas9	negative selection	2238559
26864813	26864836	8	+	24336569	HL60	viability	AGGCTACGGAGAGGATCACTAGG	ADRA1A	ENSG00000120907	0.006157356974842321	[1069]	[2273]	0	hSpCas9	negative selection	2246802
26864880	26864903	8	-	24336569	HL60	viability	TTTCCAAGGCCATTCTGCTCGGG	ADRA1A	ENSG00000120907	1.3481217072191027	[110]	[597]	8	hSpCas9	negative selection	2246803
26864890	26864913	8	+	24336569	HL60	viability	ATGGCCTTGGAAATGTTCACCGG	ADRA1A	ENSG00000120907	1.0557517758185426	[227]	[1002]	7	hSpCas9	negative selection	2246804
26864896	26864919	8	+	24336569	HL60	viability	TTGGAAATGTTCACCGGTGCCGG	ADRA1A	ENSG00000120907	0.13193953748029696	[689]	[1599]	1	hSpCas9	negative selection	2246805
26864903	26864926	8	+	24336569	HL60	viability	TGTTCACCGGTGCCGGCGGTTGG	ADRA1A	ENSG00000120907	-0.044658659630348874	[386]	[793]	0	hSpCas9	negative selection	2246806
26864909	26864932	8	-	24336569	HL60	viability	CTGCACCCAACCGCCGGCACCGG	ADRA1A	ENSG00000120907	5.686720224148029	[0]	[108]	9	hSpCas9	negative selection	2246807
26864915	26864938	8	-	24336569	HL60	viability	CTCCAACTGCACCCAACCGCCGG	ADRA1A	ENSG00000120907	0.041885328811178346	[716]	[1561]	0	hSpCas9	negative selection	2246808
26864922	26864945	8	+	24336569	HL60	viability	TTGGGTGCAGTTGGAGCTGTCGG	ADRA1A	ENSG00000120907	-0.4513839183266484	[744]	[1152]	-4	hSpCas9	negative selection	2246809
26864949	26864972	8	+	24336569	HL60	viability	ATTTCCCGAGAGAAACACCATGG	ADRA1A	ENSG00000120907	0.9213880157020955	[378]	[1518]	7	hSpCas9	negative selection	2246810
26864954	26864977	8	-	24336569	HL60	viability	TGGGACCATGGTGTTTCTCTCGG	ADRA1A	ENSG00000120907	0.003387527164905091	[552]	[1172]	0	hSpCas9	negative selection	2246811
26864813	26864836	8	+	24336569	KBM7	viability	AGGCTACGGAGAGGATCACTAGG	ADRA1A	ENSG00000120907	0.11018414943889532	[820]	[2416]	1	hSpCas9	negative selection	2313979
26864880	26864903	8	-	24336569	KBM7	viability	TTTCCAAGGCCATTCTGCTCGGG	ADRA1A	ENSG00000120907	1.2638316394132127	[130]	[857]	8	hSpCas9	negative selection	2313980
26864890	26864913	8	+	24336569	KBM7	viability	ATGGCCTTGGAAATGTTCACCGG	ADRA1A	ENSG00000120907	0.4711704829279527	[314]	[1190]	4	hSpCas9	negative selection	2313981
26864896	26864919	8	+	24336569	KBM7	viability	TTGGAAATGTTCACCGGTGCCGG	ADRA1A	ENSG00000120907	-0.06806813089917974	[554]	[1443]	0	hSpCas9	negative selection	2313982
26864903	26864926	8	+	24336569	KBM7	viability	TGTTCACCGGTGCCGGCGGTTGG	ADRA1A	ENSG00000120907	-0.27263612033994555	[286]	[647]	-2	hSpCas9	negative selection	2313983
26864909	26864932	8	-	24336569	KBM7	viability	CTGCACCCAACCGCCGGCACCGG	ADRA1A	ENSG00000120907	6.887811158145043	[0]	[322]	9	hSpCas9	negative selection	2313984
26864915	26864938	8	-	24336569	KBM7	viability	CTCCAACTGCACCCAACCGCCGG	ADRA1A	ENSG00000120907	-0.07663681962405722	[734]	[1900]	0	hSpCas9	negative selection	2313985
26864922	26864945	8	+	24336569	KBM7	viability	TTGGGTGCAGTTGGAGCTGTCGG	ADRA1A	ENSG00000120907	0.024489247766340372	[526]	[1461]	0	hSpCas9	negative selection	2313986
26864949	26864972	8	+	24336569	KBM7	viability	ATTTCCCGAGAGAAACACCATGG	ADRA1A	ENSG00000120907	-0.9562966737053432	[280]	[394]	-6	hSpCas9	negative selection	2313987
26864954	26864977	8	-	24336569	KBM7	viability	TGGGACCATGGTGTTTCTCTCGG	ADRA1A	ENSG00000120907	0.2915839533215696	[327]	[1094]	2	hSpCas9	negative selection	2313988
26853992	26854015	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAGAGAGAGAGAGGCAGAGAG	ADRA1A	ENSG00000120907	0.3003365513885732	[4,16]	[1,3]	1	dCas9-VP64	positive selection	2384815
26865511	26865534	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATGTAGGTAACTGCGGGCCAGG	ADRA1A	ENSG00000120907	-0.5093231248080683	[87,147]	[11,24]	-2	dCas9-VP64	positive selection	2461241
26865542	26865565	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAGCAGGAGCCTTCGGTGGGG	ADRA1A	ENSG00000120907	0.1387346745315734	[12,313]	[1,80]	0	dCas9-VP64	positive selection	2461242
26865480	26865503	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGTAGCGCAGCGCTACAGGTTGG	ADRA1A	ENSG00000120907	1.1817165590889025	[0,3]	[0,0]	4	dCas9-VP64	positive selection	2461243
26853992	26854015	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAGAGAGAGAGAGGCAGAGAG	ADRA1A	ENSG00000120907	0.09665185979677093	[25,42]	[8,13]	0	dCas9-VP64	positive selection	2480070
26865511	26865534	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATGTAGGTAACTGCGGGCCAGG	ADRA1A	ENSG00000120907	0.5641735904264227	[21,72]	[8,34]	4	dCas9-VP64	positive selection	2556496
26865542	26865565	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAGCAGGAGCCTTCGGTGGGG	ADRA1A	ENSG00000120907	-0.9427579093625491	[132,9]	[17,6]	-8	dCas9-VP64	positive selection	2556497
26865480	26865503	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGTAGCGCAGCGCTACAGGTTGG	ADRA1A	ENSG00000120907	3.604014639732607	[8,1]	[45,0]	9	dCas9-VP64	positive selection	2556498
26864950	26864973	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTTCCCGAGAGAAACACCATGG	ADRA1A	ENSG00000120907	0.3167315129597237	[3,3]	[4,3]	6	hSpCas9	positive selection	2969193
26864762	26864785	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACTACATCGTCAACCTGGCGG	ADRA1A	ENSG00000120907	0.19675530546845904	[4,4]	[3,4]	4	hSpCas9	positive selection	2969194
26864660	26864683	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCTTCTGCAACATCTGGGCGG	ADRA1A	ENSG00000120907	0.1150681340671802	[3,3]	[4,2]	2	hSpCas9	positive selection	2969195
26864334	26864357	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTGGCCACCACGTAGACGCGG	ADRA1A	ENSG00000120907	0.10892629307525264	[2,1]	[2,0]	2	hSpCas9	positive selection	2969196
26864950	26864973	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTTCCCGAGAGAAACACCATGG	ADRA1A	ENSG00000120907	0.7320900501555474	[3,3]	[3,4]	9	hSpCas9	positive selection	3037051
26864762	26864785	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACTACATCGTCAACCTGGCGG	ADRA1A	ENSG00000120907	0.10391691877634335	[4,4]	[3,3]	1	hSpCas9	positive selection	3037052
26864660	26864683	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCTTCTGCAACATCTGGGCGG	ADRA1A	ENSG00000120907	-0.18109025878167145	[3,3]	[4,0]	-3	hSpCas9	positive selection	3037053
26864334	26864357	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTGGCCACCACGTAGACGCGG	ADRA1A	ENSG00000120907	-0.047562037296514204	[2,2]	[2,0]	0	hSpCas9	positive selection	3037054
26864256	26864279		-	24336571	A375	resistance to PLX after 7 days	AAGTGACGCTCCGCATCCATCGG	ADRA1A	ENSG00000120907	-0.04261773812646408	[24,27]	[24,26]	-1	hSpCas9	positive selection	3107141
26770359	26770382		-	24336571	A375	resistance to PLX after 7 days	AGACGGATGGCGTTTGTGAATGG	ADRA1A	ENSG00000120907	0.027423291872567424	[43,47]	[44,48]	1	hSpCas9	positive selection	3107152
26756748	26756771		+	24336571	A375	resistance to PLX after 7 days	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	-0.03154548936653223	[14,11]	[13,12]	-1	hSpCas9	positive selection	3107162
26766072	26766095		-	24336571	A375	resistance to PLX after 7 days	TGAATTTTATGATGCCACCGTGG	ADRA1A	ENSG00000120907	-0.24522765763300158	[9,12]	[8,9]	-7	hSpCas9	positive selection	3107174
26770362	26770385		+	24336571	A375	resistance to PLX after 7 days	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.01098613949381555	[109,100]	[110,99]	0	hSpCas9	positive selection	3107185
26864277	26864300		+	24336571	A375	resistance to PLX after 7 days	TTGCTCCGAGTCCGACTTGTCGG	ADRA1A	ENSG00000120907	-0.3326422899335181	[24,28]	[22,19]	-8	hSpCas9	positive selection	3107196
26864256	26864279		-	24336571	A375	resistance to PLX after 14 days	AAGTGACGCTCCGCATCCATCGG	ADRA1A	ENSG00000120907	-0.20603963604790232	[27,22]	[8,10]	-2	hSpCas9	positive selection	3164934
26770359	26770382		-	24336571	A375	resistance to PLX after 14 days	AGACGGATGGCGTTTGTGAATGG	ADRA1A	ENSG00000120907	0.49127353315378897	[44,56]	[31,33]	4	hSpCas9	positive selection	3164945
26756748	26756771		+	24336571	A375	resistance to PLX after 14 days	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	-0.4319553261855333	[17,8]	[3,4]	-5	hSpCas9	positive selection	3164955
26766072	26766095		-	24336571	A375	resistance to PLX after 14 days	TGAATTTTATGATGCCACCGTGG	ADRA1A	ENSG00000120907	-0.12306511426789107	[9,7]	[3,2]	-1	hSpCas9	positive selection	3164967
26770362	26770385		+	24336571	A375	resistance to PLX after 14 days	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	-0.3944522527445744	[118,92]	[34,39]	-5	hSpCas9	positive selection	3164978
26864277	26864300		+	24336571	A375	resistance to PLX after 14 days	TTGCTCCGAGTCCGACTTGTCGG	ADRA1A	ENSG00000120907	-0.3489775004859489	[23,31]	[8,10]	-4	hSpCas9	positive selection	3164989
26864256	26864279		-	24336571	A375	viability after 7 days	AAGTGACGCTCCGCATCCATCGG	ADRA1A	ENSG00000120907	0.48930980987498196	[19]	[24,27]	7	hSpCas9	negative selection	3222727
26770359	26770382		-	24336571	A375	viability after 7 days	AGACGGATGGCGTTTGTGAATGG	ADRA1A	ENSG00000120907	0.34435305582499187	[37]	[43,47]	5	hSpCas9	negative selection	3222738
26756748	26756771		+	24336571	A375	viability after 7 days	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.2704754640972163	[11]	[14,11]	4	hSpCas9	negative selection	3222748
26766072	26766095		-	24336571	A375	viability after 7 days	TGAATTTTATGATGCCACCGTGG	ADRA1A	ENSG00000120907	0.39713706627939654	[8]	[9,12]	6	hSpCas9	negative selection	3222760
26770362	26770385		+	24336571	A375	viability after 7 days	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.3729797730665112	[85]	[109,100]	5	hSpCas9	negative selection	3222771
26864277	26864300		+	24336571	A375	viability after 7 days	TTGCTCCGAGTCCGACTTGTCGG	ADRA1A	ENSG00000120907	0.3504506405222265	[22]	[24,28]	5	hSpCas9	negative selection	3222782
26864256	26864279		-	24336571	A375	viability after 14 days	AAGTGACGCTCCGCATCCATCGG	ADRA1A	ENSG00000120907	0.4409375803515322	[19]	[27,22]	5	hSpCas9	negative selection	3280520
26770359	26770382		-	24336571	A375	viability after 14 days	AGACGGATGGCGTTTGTGAATGG	ADRA1A	ENSG00000120907	0.5021920003358082	[37]	[44,56]	6	hSpCas9	negative selection	3280531
26756748	26756771		+	24336571	A375	viability after 14 days	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.28462010044206365	[11]	[17,8]	3	hSpCas9	negative selection	3280541
26766072	26766095		-	24336571	A375	viability after 14 days	TGAATTTTATGATGCCACCGTGG	ADRA1A	ENSG00000120907	0.08283563880940831	[8]	[9,7]	1	hSpCas9	negative selection	3280553
26770362	26770385		+	24336571	A375	viability after 14 days	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.40187328360762287	[85]	[118,92]	5	hSpCas9	negative selection	3280564
26864277	26864300		+	24336571	A375	viability after 14 days	TTGCTCCGAGTCCGACTTGTCGG	ADRA1A	ENSG00000120907	0.40395107772674765	[22]	[23,31]	5	hSpCas9	negative selection	3280575
26770389	26770412	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.38269637442510085	[93,140]	[0,0]	2	hSpCas9	positive selection	3335776
26770362	26770385	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	-1.7234480758563924	[538,470]	[0,0]	-9	hSpCas9	positive selection	3335777
26756748	26756771	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	1.885585150110315	[26,55]	[0,0]	7	hSpCas9	positive selection	3335778
26766102	26766125	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	-2.3720304086337745	[791,791]	[0,0]	-9	hSpCas9	positive selection	3355025
26766055	26766078	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.30312990105895976	[123,123]	[0,0]	1	hSpCas9	positive selection	3355026
26748725	26748748	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGAAGTCTCGCTCTGTCACCAGG	ADRA1A	ENSG00000120907	0.8143827155971068	[86,86]	[0,0]	4	hSpCas9	positive selection	3355027
26864949	26864972	8	+	26780180	HT29	viability (Avana library 4 designs)	ATTTCCCGAGAGAAACACCATGG	ADRA1A	ENSG00000120907	0.0240470186202291	[]	[]	0	hSpCas9	negative selection	3405257
26864762	26864785	8	-	26780180	HT29	viability (Avana library 4 designs)	CTACTACATCGTCAACCTGGCGG	ADRA1A	ENSG00000120907	0.366033267292943	[]	[]	1	hSpCas9	negative selection	3405258
26864660	26864683	8	-	26780180	HT29	viability (Avana library 4 designs)	GGTCTTCTGCAACATCTGGGCGG	ADRA1A	ENSG00000120907	-1.10735201744077	[]	[]	-9	hSpCas9	negative selection	3405259
26864333	26864356	8	+	26780180	HT29	viability (Avana library 4 designs)	TCTTGGCCACCACGTAGACGCGG	ADRA1A	ENSG00000120907	0.215858645825184	[]	[]	0	hSpCas9	negative selection	3405260
26864660	26864683	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCTTCTGCAACATCTGGGCGG	ADRA1A	ENSG00000120907	3.90830418642702	[]	[]	6	hSpCas9	negative selection	3477180
26864949	26864972	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTTCCCGAGAGAAACACCATGG	ADRA1A	ENSG00000120907	-5.61362315000609	[]	[]	-6	hSpCas9	negative selection	3477181
26864762	26864785	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACTACATCGTCAACCTGGCGG	ADRA1A	ENSG00000120907	-2.63444705547395	[]	[]	-3	hSpCas9	negative selection	3477182
26864333	26864356	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGGCCACCACGTAGACGCGG	ADRA1A	ENSG00000120907	6.44448325086374	[]	[]	9	hSpCas9	negative selection	3477183
26864429	26864452	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACCATCTGCCAGATCAACGAGG	ADRA1A	ENSG00000120907	-6.33249550756988	[]	[]	-6	hSpCas9	negative selection	3477184
26864759	26864782	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	5.26279541853035	[]	[]	8	hSpCas9	negative selection	3477185
26864660	26864683	8	-	26780180	A375	viability (Avana lentiGuide)	GGTCTTCTGCAACATCTGGGCGG	ADRA1A	ENSG00000120907	-0.639058870119187	[]	[]	-1	hSpCas9	negative selection	3585839
26864949	26864972	8	+	26780180	A375	viability (Avana lentiGuide)	ATTTCCCGAGAGAAACACCATGG	ADRA1A	ENSG00000120907	-2.02822773467564	[]	[]	-3	hSpCas9	negative selection	3585840
26864762	26864785	8	-	26780180	A375	viability (Avana lentiGuide)	CTACTACATCGTCAACCTGGCGG	ADRA1A	ENSG00000120907	1.3767013721619	[]	[]	1	hSpCas9	negative selection	3585841
26864333	26864356	8	+	26780180	A375	viability (Avana lentiGuide)	TCTTGGCCACCACGTAGACGCGG	ADRA1A	ENSG00000120907	15.1823647261532	[]	[]	8	hSpCas9	negative selection	3585842
26864429	26864452	8	-	26780180	A375	viability (Avana lentiGuide)	GACCATCTGCCAGATCAACGAGG	ADRA1A	ENSG00000120907	0.0882365282291244	[]	[]	0	hSpCas9	negative selection	3585843
26864759	26864782	8	-	26780180	A375	viability (Avana lentiGuide)	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	1.49364792671232	[]	[]	1	hSpCas9	negative selection	3585844
26864660	26864683	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCTTCTGCAACATCTGGGCGG	ADRA1A	ENSG00000120907	0.02693561251267872	[4]	[5,3]	0	hSpCas9	positive selection	3694498
26864949	26864972	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTTCCCGAGAGAAACACCATGG	ADRA1A	ENSG00000120907	-0.7840040067373149	[5]	[2,2]	-8	hSpCas9	positive selection	3694499
26864762	26864785	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACTACATCGTCAACCTGGCGG	ADRA1A	ENSG00000120907	-0.1568784991631616	[5]	[5,3]	-3	hSpCas9	positive selection	3694500
26864333	26864356	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGGCCACCACGTAGACGCGG	ADRA1A	ENSG00000120907	0.1342033514373651	[4]	[4,3]	3	hSpCas9	positive selection	3694501
26864429	26864452	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCATCTGCCAGATCAACGAGG	ADRA1A	ENSG00000120907	-0.06668860935686968	[4]	[4,3]	-1	hSpCas9	positive selection	3694502
26864759	26864782	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.2180638933581851	[5]	[6,6]	6	hSpCas9	positive selection	3694503
26864660	26864683	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCTTCTGCAACATCTGGGCGG	ADRA1A	ENSG00000120907	0.3401165006355418	[5]	[5,6]	8	hSpCas9	positive selection	3803105
26864949	26864972	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTTCCCGAGAGAAACACCATGG	ADRA1A	ENSG00000120907	-0.9499467939141083	[5]	[2,1]	-8	hSpCas9	positive selection	3803106
26864762	26864785	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACTACATCGTCAACCTGGCGG	ADRA1A	ENSG00000120907	0.10345124846559026	[6]	[7,4]	2	hSpCas9	positive selection	3803107
26864333	26864356	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGGCCACCACGTAGACGCGG	ADRA1A	ENSG00000120907	-0.09500578832825685	[3]	[3,2]	-1	hSpCas9	positive selection	3803108
26864429	26864452	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCATCTGCCAGATCAACGAGG	ADRA1A	ENSG00000120907	0.16329375575297514	[5]	[4,5]	4	hSpCas9	positive selection	3803109
26864759	26864782	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.35602581589815974	[6]	[6,6]	9	hSpCas9	positive selection	3803110
26766055	26766078	8	+	26780180	A375	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	1.42175816378147	[]	[]	7	hSpCas9	negative selection	3911569
26766102	26766125	8	+	26780180	A375	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.0748711328672492	[]	[]	0	hSpCas9	negative selection	3911570
26770389	26770412	8	-	26780180	A375	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.936419942397597	[]	[]	4	hSpCas9	negative selection	3911571
26756748	26756771	8	+	26780180	A375	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.752026582660436	[]	[]	2	hSpCas9	negative selection	3911572
26770362	26770385	8	+	26780180	A375	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	-0.0702396039473251	[]	[]	-2	hSpCas9	negative selection	3911573
26766055	26766078	8	+	26780180	HT29	viability (GeCKOv2 library)	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	1.35952155183728	[]	[]	7	hSpCas9	negative selection	4019535
26766102	26766125	8	+	26780180	HT29	viability (GeCKOv2 library)	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	-0.375776477820251	[]	[]	-8	hSpCas9	negative selection	4019536
26770389	26770412	8	-	26780180	HT29	viability (GeCKOv2 library)	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	1.19258490054576	[]	[]	6	hSpCas9	negative selection	4019537
26756748	26756771	8	+	26780180	HT29	viability (GeCKOv2 library)	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	-0.0626356893609885	[]	[]	-2	hSpCas9	negative selection	4019538
26770362	26770385	8	+	26780180	HT29	viability (GeCKOv2 library)	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.246536935487286	[]	[]	0	hSpCas9	negative selection	4019539
26864256	26864279	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGTGACGCTCCGCATCCATCGG	ADRA1A	ENSG00000120907	0.07447888585894358	[4]	[3,3]	2	hSpCas9	positive selection	4129380
26770359	26770382	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACGGATGGCGTTTGTGAATGG	ADRA1A	ENSG00000120907	0.5718784990661416	[5]	[6,5]	9	hSpCas9	positive selection	4129391
26756748	26756771	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	-0.19244233151561835	[3]	[1,1]	-4	hSpCas9	positive selection	4129401
26766072	26766095	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAATTTTATGATGCCACCGTGG	ADRA1A	ENSG00000120907	-0.07998275827649082	[4]	[3,1]	-2	hSpCas9	positive selection	4129413
26770362	26770385	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.40256029976971885	[6]	[6,5]	8	hSpCas9	positive selection	4129424
26864277	26864300	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGCTCCGAGTCCGACTTGTCGG	ADRA1A	ENSG00000120907	0.10511333225228989	[4]	[2,3]	2	hSpCas9	positive selection	4129435
26864256	26864279	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGTGACGCTCCGCATCCATCGG	ADRA1A	ENSG00000120907	0.8694318876025542	[5]	[4,4,2,4]	6	hSpCas9	positive selection	4193402
26770359	26770382	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACGGATGGCGTTTGTGAATGG	ADRA1A	ENSG00000120907	0.8770410845900485	[5]	[2,4,4,4]	6	hSpCas9	positive selection	4193413
26756748	26756771	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	-0.07023859709043989	[3]	[3,2,0,0]	-1	hSpCas9	positive selection	4193423
26766072	26766095	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAATTTTATGATGCCACCGTGG	ADRA1A	ENSG00000120907	1.0436684125633835	[2]	[1,0,1,2]	7	hSpCas9	positive selection	4193435
26770362	26770385	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.6873373684242088	[6]	[6,4,5,3]	4	hSpCas9	positive selection	4193446
26864277	26864300	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGCTCCGAGTCCGACTTGTCGG	ADRA1A	ENSG00000120907	1.0170587072576032	[4]	[4,0,4,4]	7	hSpCas9	positive selection	4193457
26770389	26770412	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.03064768186287431	[2]	[1,1]	0	hSpCas9	positive selection	4254740
26770362	26770385	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.43098295771556777	[4]	[4,4]	8	hSpCas9	positive selection	4254741
26756748	26756771	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.025818405458016724	[1]	[1,0]	0	hSpCas9	positive selection	4254742
26766102	26766125	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.5727777966641056	[4]	[5,5]	9	hSpCas9	positive selection	4319022
26766055	26766078	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.312589178810708	[2]	[2,2]	6	hSpCas9	positive selection	4319023
26864443	26864465	8	+	27760321	OCIAML3	viability	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	-0.11750378716810284	[843,689]	[455,672]	-1	hSpCas9	negative selection	4376506
26864475	26864497	8	-	27760321	OCIAML3	viability	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.5718529079512087	[1262,952]	[1158,1431]	6	hSpCas9	negative selection	4376507
26864544	26864566	8	-	27760321	OCIAML3	viability	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	0.6258579524580007	[564,404]	[508,670]	7	hSpCas9	negative selection	4376508
26864694	26864716	8	-	27760321	OCIAML3	viability	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	-0.020540039765021834	[356,308]	[249,263]	0	hSpCas9	negative selection	4376509
26864805	26864827	8	+	27760321	OCIAML3	viability	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.3628475804876492	[497,466]	[439,544]	4	hSpCas9	negative selection	4376510
26864443	26864465	8	+	27760321	OCIAML2	viability	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.2207126060796879	[843,689]	[589,889]	3	hSpCas9	negative selection	4459969
26864475	26864497	8	-	27760321	OCIAML2	viability	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.12810665844782032	[1262,952]	[914,1045]	1	hSpCas9	negative selection	4459970
26864544	26864566	8	-	27760321	OCIAML2	viability	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	-0.1142743007279855	[564,404]	[290,447]	-1	hSpCas9	negative selection	4459971
26864694	26864716	8	-	27760321	OCIAML2	viability	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	0.24161716972416744	[356,308]	[283,361]	3	hSpCas9	negative selection	4459972
26864805	26864827	8	+	27760321	OCIAML2	viability	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.0881095832034216	[497,466]	[368,475]	1	hSpCas9	negative selection	4459973
26864443	26864465	8	+	27760321	MV411	viability	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	-0.038669937490952044	[843,689]	[387,643]	0	hSpCas9	negative selection	4543432
26864475	26864497	8	-	27760321	MV411	viability	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	-0.24629211323249423	[1262,952]	[329,1033]	-2	hSpCas9	negative selection	4543433
26864544	26864566	8	-	27760321	MV411	viability	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	-1.4153698665343089	[564,404]	[71,188]	-7	hSpCas9	negative selection	4543434
26864694	26864716	8	-	27760321	MV411	viability	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	0.14419124934987942	[356,308]	[248,231]	1	hSpCas9	negative selection	4543435
26864805	26864827	8	+	27760321	MV411	viability	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.20166078362352516	[497,466]	[373,354]	1	hSpCas9	negative selection	4543436
26864443	26864465	8	+	27760321	HL60	viability	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.3594036006161111	[843,689]	[693,911]	4	hSpCas9	negative selection	4626895
26864475	26864497	8	-	27760321	HL60	viability	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.3761204472494748	[1262,952]	[1116,1215]	4	hSpCas9	negative selection	4626896
26864544	26864566	8	-	27760321	HL60	viability	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	-0.03632519659505368	[564,404]	[460,298]	0	hSpCas9	negative selection	4626897
26864694	26864716	8	-	27760321	HL60	viability	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	-0.1263133311409701	[356,308]	[233,263]	-1	hSpCas9	negative selection	4626898
26864805	26864827	8	+	27760321	HL60	viability	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	-0.021995490278942043	[497,466]	[468,302]	0	hSpCas9	negative selection	4626899
26864443	26864465	8	+	27760321	HT1080	viability	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.6925803429123939	[689,538]	[398,391]	3	hSpCas9	negative selection	4710358
26864475	26864497	8	-	27760321	HT1080	viability	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.49498840819697776	[952,743]	[378,582]	2	hSpCas9	negative selection	4710359
26864544	26864566	8	-	27760321	HT1080	viability	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	0.5934280660369249	[404,315]	[72,373]	3	hSpCas9	negative selection	4710360
26864694	26864716	8	-	27760321	HT1080	viability	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	1.3572618368596867	[308,240]	[283,276]	7	hSpCas9	negative selection	4710361
26864805	26864827	8	+	27760321	HT1080	viability	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.9064026850976223	[466,364]	[218,410]	5	hSpCas9	negative selection	4710362
26864443	26864465	8	+	27760321	HT29	viability after 7 days	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.4496081926199239	[689,538]	[1346,982,947]	7	hSpCas9	negative selection	4793821
26864475	26864497	8	-	27760321	HT29	viability after 7 days	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.461036766315819	[952,743]	[1945,1711,926]	7	hSpCas9	negative selection	4793822
26864544	26864566	8	-	27760321	HT29	viability after 7 days	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	0.12577630794150058	[404,315]	[624,325,579]	2	hSpCas9	negative selection	4793823
26864694	26864716	8	-	27760321	HT29	viability after 7 days	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	0.20236316859024606	[308,240]	[529,447,263]	3	hSpCas9	negative selection	4793824
26864805	26864827	8	+	27760321	HT29	viability after 7 days	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	-0.2906991453468439	[466,364]	[456,354,499]	-4	hSpCas9	negative selection	4793825
26864443	26864465	8	+	27760321	HT29	viability after 25 days	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.5914004012978157	[689,538]	[1081,1094,986]	6	hSpCas9	negative selection	4877284
26864475	26864497	8	-	27760321	HT29	viability after 25 days	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.2910567076351731	[952,743]	[1064,1203,1308]	3	hSpCas9	negative selection	4877285
26864544	26864566	8	-	27760321	HT29	viability after 25 days	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	0.1772169458769445	[404,315]	[387,501,516]	1	hSpCas9	negative selection	4877286
26864694	26864716	8	-	27760321	HT29	viability after 25 days	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	0.5702059672730916	[308,240]	[456,550,382]	6	hSpCas9	negative selection	4877287
26864805	26864827	8	+	27760321	HT29	viability after 25 days	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.4039058069300822	[466,364]	[576,532,796]	4	hSpCas9	negative selection	4877288
26864443	26864465	8	+	27760321	HT29	viability after 22 days	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.44880093672070676	[689,538]	[983,911,1012]	5	hSpCas9	negative selection	4960747
26864475	26864497	8	-	27760321	HT29	viability after 22 days	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.6626159664323974	[952,743]	[1448,1555,1656]	7	hSpCas9	negative selection	4960748
26864544	26864566	8	-	27760321	HT29	viability after 22 days	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	0.4763610651077418	[404,315]	[453,578,710]	5	hSpCas9	negative selection	4960749
26864694	26864716	8	-	27760321	HT29	viability after 22 days	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	0.4903787743123694	[308,240]	[508,493,333]	5	hSpCas9	negative selection	4960750
26864805	26864827	8	+	27760321	HT29	viability after 22 days	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.4817116249302011	[466,364]	[480,653,886]	5	hSpCas9	negative selection	4960751
26864443	26864465	8	+	27760321	HT29	viability after 19 days	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.548867460758934	[689,538]	[847,1375,847]	5	hSpCas9	negative selection	5044210
26864475	26864497	8	-	27760321	HT29	viability after 19 days	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.30999201360998696	[952,743]	[1325,1435,871]	3	hSpCas9	negative selection	5044211
26864544	26864566	8	-	27760321	HT29	viability after 19 days	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	0.4286169187204319	[404,315]	[388,300,941]	4	hSpCas9	negative selection	5044212
26864694	26864716	8	-	27760321	HT29	viability after 19 days	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	0.8251843760580926	[308,240]	[573,433,660]	8	hSpCas9	negative selection	5044213
26864805	26864827	8	+	27760321	HT29	viability after 19 days	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.44926154174297733	[466,364]	[612,717,614]	4	hSpCas9	negative selection	5044214
26864443	26864465	8	+	27760321	HT29	viability after 16 days	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.48741600825593034	[689,538]	[1166,1028,712]	5	hSpCas9	negative selection	5127673
26864475	26864497	8	-	27760321	HT29	viability after 16 days	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.3667829249488308	[952,743]	[1695,946,1080]	4	hSpCas9	negative selection	5127674
26864544	26864566	8	-	27760321	HT29	viability after 16 days	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	0.40796563436134986	[404,315]	[491,505,603]	4	hSpCas9	negative selection	5127675
26864694	26864716	8	-	27760321	HT29	viability after 16 days	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	0.30400730338995147	[308,240]	[386,459,290]	3	hSpCas9	negative selection	5127676
26864805	26864827	8	+	27760321	HT29	viability after 16 days	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.2203605056197243	[466,364]	[492,583,543]	2	hSpCas9	negative selection	5127677
26864443	26864465	8	+	27760321	HT29	viability after 13 days	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.3270937693826851	[689,538]	[1189,764,736]	4	hSpCas9	negative selection	5211136
26864475	26864497	8	-	27760321	HT29	viability after 13 days	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.6276024942984129	[952,743]	[1689,1489,1389]	7	hSpCas9	negative selection	5211137
26864544	26864566	8	-	27760321	HT29	viability after 13 days	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	0.35770487906332427	[404,315]	[440,429,724]	4	hSpCas9	negative selection	5211138
26864694	26864716	8	-	27760321	HT29	viability after 13 days	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	0.12288240081074525	[308,240]	[274,517,254]	1	hSpCas9	negative selection	5211139
26864805	26864827	8	+	27760321	HT29	viability after 13 days	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.0639343991628436	[466,364]	[562,269,669]	0	hSpCas9	negative selection	5211140
26864443	26864465	8	+	27760321	HT29	viability after 10 days	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.31539742933390913	[689,538]	[1259,674,921]	4	hSpCas9	negative selection	5294599
26864475	26864497	8	-	27760321	HT29	viability after 10 days	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	0.38098179416017186	[952,743]	[1499,1293,1342]	5	hSpCas9	negative selection	5294600
26864544	26864566	8	-	27760321	HT29	viability after 10 days	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	0.057275188128948926	[404,315]	[434,344,617]	0	hSpCas9	negative selection	5294601
26864694	26864716	8	-	27760321	HT29	viability after 10 days	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	0.07143812485030587	[308,240]	[248,445,388]	0	hSpCas9	negative selection	5294602
26864805	26864827	8	+	27760321	HT29	viability after 10 days	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	-0.30011710234664113	[466,364]	[506,371,385]	-4	hSpCas9	negative selection	5294603
26864443	26864465	8	+	27760321	MOLM13	viability	CAGATGGTCTCGTCCTCGGGGG	ADRA1A	ENSG00000120907	0.7146255755819549	[843,689]	[213,1125]	5	hSpCas9	negative selection	5378062
26864475	26864497	8	-	27760321	MOLM13	viability	CATTGGACCCCTGTTCGGCTGG	ADRA1A	ENSG00000120907	1.0771064217324018	[1262,952]	[1844,850]	7	hSpCas9	negative selection	5378063
26864544	26864566	8	-	27760321	MOLM13	viability	AACCATCGTCACCCAGAGGAGG	ADRA1A	ENSG00000120907	-0.3790113736561255	[564,404]	[150,256]	-2	hSpCas9	negative selection	5378064
26864694	26864716	8	-	27760321	MOLM13	viability	CTTCGAGGTCCTAGGCTACTGG	ADRA1A	ENSG00000120907	-1.0126143799523122	[356,308]	[107,79]	-6	hSpCas9	negative selection	5378065
26864805	26864827	8	+	27760321	MOLM13	viability	TCGGTGACAGGCTACGGAGAGG	ADRA1A	ENSG00000120907	0.3452713647909539	[497,466]	[230,443]	2	hSpCas9	negative selection	5378066
26866805	26866828	8	+	27661255	K562	viability	GGGGCCGGTATAAAACCTGGTGG	ADRA1A	ENSG00000120907	-0.09408843492386708	[752,801]	[679,496]	-3	dCas9-KRAB	negative selection	5461179
26866835	26866858	8	+	27661255	K562	viability	GGGAGGCGCTGGGAAAAGTGGGG	ADRA1A	ENSG00000120907	0.1787554769944517	[961,1154]	[1015,900]	6	dCas9-KRAB	negative selection	5461180
26867228	26867251	8	+	27661255	K562	viability	GACACCAGAAAAGAATAGCAAGG	ADRA1A	ENSG00000120907	-0.12821104401534256	[867,808]	[699,539]	-4	dCas9-KRAB	negative selection	5461181
26770389	26770412	8	-	27260156	BXPC3	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.13237535292444141	[359]	[450,315,436,449]	3	hSpCas9	negative selection	5527200
26770362	26770385	8	+	27260156	BXPC3	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.22586498269541266	[1420]	[1483,1841,1727,1928]	5	hSpCas9	negative selection	5527201
26756748	26756771	8	+	27260156	BXPC3	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.4359404021763593	[89]	[102,146,147,109]	8	hSpCas9	negative selection	5527202
26766102	26766125	8	+	27260156	BXPC3	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.30984956963161014	[1549]	[1867,1921,2116,2154]	6	hSpCas9	negative selection	5591482
26766055	26766078	8	+	27260156	BXPC3	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.039629148951077386	[300]	[238,284,286,435]	-1	hSpCas9	negative selection	5591483
26770389	26770412	8	-	27260156	A673	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.22049140844832302	[359]	[515,483,517,496]	5	hSpCas9	negative selection	5648451
26770362	26770385	8	+	27260156	A673	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.24398954067713774	[1420]	[2457,1742,1961,1970]	6	hSpCas9	negative selection	5648452
26756748	26756771	8	+	27260156	A673	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.009194739657650164	[89]	[145,97,109,83]	0	hSpCas9	negative selection	5648453
26766102	26766125	8	+	27260156	A673	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.1185301732887809	[1549]	[2270,1694,2191,1951]	3	hSpCas9	negative selection	5712733
26766055	26766078	8	+	27260156	A673	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.23023121371259098	[300]	[422,333,374,573]	5	hSpCas9	negative selection	5712734
26770389	26770412	8	-	27260156	A375	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.03872527259521663	[359]	[409,348,510,362]	0	hSpCas9	negative selection	5769702
26770362	26770385	8	+	27260156	A375	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.436983515989285	[1420]	[2750,2545,1849,1916]	6	hSpCas9	negative selection	5769703
26756748	26756771	8	+	27260156	A375	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.888488268457583	[89]	[153,142,276,195]	9	hSpCas9	negative selection	5769704
26766102	26766125	8	+	27260156	A375	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.5665997765712896	[1549]	[2865,3000,2449,2468]	8	hSpCas9	negative selection	5833984
26766055	26766078	8	+	27260156	A375	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.22224413935881682	[300]	[216,334,406,254]	-3	hSpCas9	negative selection	5833985
26770389	26770412	8	-	27260156	COLO741	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.044624954418642504	[359]	[334,494,493]	-1	hSpCas9	negative selection	5890953
26770362	26770385	8	+	27260156	COLO741	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.2423856656657486	[1420]	[2384,1797,2265]	5	hSpCas9	negative selection	5890954
26756748	26756771	8	+	27260156	COLO741	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.1333595606439144	[89]	[224,72,90]	3	hSpCas9	negative selection	5890955
26766102	26766125	8	+	27260156	COLO741	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.20667988869138898	[1549]	[2188,2530,2134]	4	hSpCas9	negative selection	5955235
26766055	26766078	8	+	27260156	COLO741	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.5070274368540895	[300]	[743,520,400]	8	hSpCas9	negative selection	5955236
26770389	26770412	8	-	27260156	CAL120	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.07639511479530992	[359]	[298,614,342]	-1	hSpCas9	negative selection	6012204
26770362	26770385	8	+	27260156	CAL120	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.3063743533597836	[1420]	[2415,1793,2379]	4	hSpCas9	negative selection	6012205
26756748	26756771	8	+	27260156	CAL120	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.8723257421163777	[89]	[152,240,212]	9	hSpCas9	negative selection	6012206
26766102	26766125	8	+	27260156	CAL120	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.20655196230699002	[1549]	[2848,2089,1837]	3	hSpCas9	negative selection	6076486
26766055	26766078	8	+	27260156	CAL120	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.2656014070615108	[300]	[457,454,438]	4	hSpCas9	negative selection	6076487
26770389	26770412	8	-	27260156	CADOES1	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.17552863062545976	[359]	[251,279,380,271]	-3	hSpCas9	negative selection	6133455
26770362	26770385	8	+	27260156	CADOES1	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.35026630692377436	[1420]	[1424,1834,1491,1999]	6	hSpCas9	negative selection	6133456
26756748	26756771	8	+	27260156	CADOES1	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	-0.47782203838322124	[89]	[51,50,87,48]	-7	hSpCas9	negative selection	6133457
26766102	26766125	8	+	27260156	CADOES1	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.4008649853624413	[1549]	[1802,1584,1781,2463]	6	hSpCas9	negative selection	6197737
26766055	26766078	8	+	27260156	CADOES1	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.03838091026281709	[300]	[230,287,320,310]	0	hSpCas9	negative selection	6197738
26770389	26770412	8	-	27260156	EWS502	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.05122392209105131	[359]	[330,500,400,226]	-1	hSpCas9	negative selection	6254706
26770362	26770385	8	+	27260156	EWS502	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.30994723070810526	[1420]	[1761,2052,1886,1750]	5	hSpCas9	negative selection	6254707
26756748	26756771	8	+	27260156	EWS502	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.4765242944631862	[89]	[86,120,178,150]	8	hSpCas9	negative selection	6254708
26766102	26766125	8	+	27260156	EWS502	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.2894234891262979	[1549]	[1788,1911,2359,1990]	5	hSpCas9	negative selection	6318988
26766055	26766078	8	+	27260156	EWS502	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.1556391566091999	[300]	[227,188,406,335]	-3	hSpCas9	negative selection	6318989
26770389	26770412	8	-	27260156	EW8	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.8754161507731448	[359]	[400,1131,359,264]	9	hSpCas9	negative selection	6375957
26770362	26770385	8	+	27260156	EW8	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.3481498041923816	[1420]	[1858,1354,1170,1566]	6	hSpCas9	negative selection	6375958
26756748	26756771	8	+	27260156	EW8	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.12389844630424562	[89]	[71,111,37,101]	2	hSpCas9	negative selection	6375959
26766102	26766125	8	+	27260156	EW8	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.3662842615134334	[1549]	[1689,1733,1504,1570]	6	hSpCas9	negative selection	6440239
26766055	26766078	8	+	27260156	EW8	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.18713087133654466	[300]	[244,321,251,291]	3	hSpCas9	negative selection	6440240
26770389	26770412	8	-	27260156	CORL105	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.10342529355112595	[359]	[500,413,637,289]	2	hSpCas9	negative selection	6497208
26770362	26770385	8	+	27260156	CORL105	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.2804015993641371	[1420]	[1969,1908,2196,2032]	5	hSpCas9	negative selection	6497209
26756748	26756771	8	+	27260156	CORL105	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.9987558111012771	[89]	[67,194,298,288]	9	hSpCas9	negative selection	6497210
26766102	26766125	8	+	27260156	CORL105	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.5177395440229446	[1549]	[2605,2459,2702,2640]	8	hSpCas9	negative selection	6561490
26766055	26766078	8	+	27260156	CORL105	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.011445087780412089	[300]	[355,366,341,331]	0	hSpCas9	negative selection	6561491
26770389	26770412	8	-	27260156	HS294T	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.5353366810220619	[359]	[134,224,214,243]	7	hSpCas9	negative selection	6618459
26770362	26770385	8	+	27260156	HS294T	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.29667394654187507	[1420]	[643,710,508,866]	4	hSpCas9	negative selection	6618460
26756748	26756771	8	+	27260156	HS294T	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.33571008432776583	[89]	[37,46,41,49]	4	hSpCas9	negative selection	6618461
26766102	26766125	8	+	27260156	HS294T	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.8770706233889487	[1549]	[925,1223,1080,1196]	9	hSpCas9	negative selection	6682741
26766055	26766078	8	+	27260156	HS294T	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.5787341882749435	[300]	[50,79,79,107]	-7	hSpCas9	negative selection	6682742
26770389	26770412	8	-	27260156	HCC44	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.10355538645334167	[359]	[353,287,376,499]	-2	hSpCas9	negative selection	6739710
26770362	26770385	8	+	27260156	HCC44	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.5300454639929912	[1420]	[2506,1875,3084,2017]	8	hSpCas9	negative selection	6739711
26756748	26756771	8	+	27260156	HCC44	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.8080651989825187	[89]	[273,189,73,162]	9	hSpCas9	negative selection	6739712
26766102	26766125	8	+	27260156	HCC44	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.29148382250593174	[1549]	[2509,1716,2489,2005]	5	hSpCas9	negative selection	6803992
26766055	26766078	8	+	27260156	HCC44	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.3545446886870518	[300]	[433,330,427,553]	6	hSpCas9	negative selection	6803993
26770389	26770412	8	-	27260156	G402	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.009701752754131487	[359]	[378,642,323,402]	0	hSpCas9	negative selection	6860961
26770362	26770385	8	+	27260156	G402	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.6280859947862025	[1420]	[2595,3354,2680,2130]	7	hSpCas9	negative selection	6860962
26756748	26756771	8	+	27260156	G402	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	1.0462969486676903	[89]	[453,217,153,117]	9	hSpCas9	negative selection	6860963
26766102	26766125	8	+	27260156	G402	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.6166612849462916	[1549]	[3775,2069,3366,2474]	7	hSpCas9	negative selection	6925243
26766055	26766078	8	+	27260156	G402	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.2994227909116045	[300]	[535,403,559,321]	4	hSpCas9	negative selection	6925244
26770389	26770412	8	-	27260156	L33	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.597756457508394	[359]	[553,220,370,495]	9	hSpCas9	negative selection	6982212
26770362	26770385	8	+	27260156	L33	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.15672858320241834	[1420]	[1699,606,1036,1502]	3	hSpCas9	negative selection	6982213
26756748	26756771	8	+	27260156	L33	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.3571649812508455	[89]	[138,51,84,59]	7	hSpCas9	negative selection	6982214
26766102	26766125	8	+	27260156	L33	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.4246749931257692	[1549]	[2041,918,1242,2059]	8	hSpCas9	negative selection	7046494
26766055	26766078	8	+	27260156	L33	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.09311707877308129	[300]	[318,158,186,279]	2	hSpCas9	negative selection	7046495
26770389	26770412	8	-	27260156	K562	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.8771970499620859	[359]	[585,300,594,819]	9	hSpCas9	negative selection	7103463
26770362	26770385	8	+	27260156	K562	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.6655552295404876	[1420]	[1976,2303,1994,1758]	8	hSpCas9	negative selection	7103464
26756748	26756771	8	+	27260156	K562	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.39266712623539934	[89]	[57,186,55,116]	5	hSpCas9	negative selection	7103465
26766102	26766125	8	+	27260156	K562	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.4190528054181395	[1549]	[2113,2213,1894,1238]	5	hSpCas9	negative selection	7167745
26766055	26766078	8	+	27260156	K562	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.034113107371014695	[300]	[259,284,477,90]	0	hSpCas9	negative selection	7167746
26770389	26770412	8	-	27260156	HT29	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.23175443813585098	[359]	[509,493,533,511]	4	hSpCas9	negative selection	7224714
26770362	26770385	8	+	27260156	HT29	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.3305560103870766	[1420]	[2384,2246,2154,1937]	6	hSpCas9	negative selection	7224715
26756748	26756771	8	+	27260156	HT29	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.09483361858339068	[89]	[133,214,88,46]	1	hSpCas9	negative selection	7224716
26766102	26766125	8	+	27260156	HT29	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.2572901436431685	[1549]	[2762,2425,2080,1828]	5	hSpCas9	negative selection	7288996
26766055	26766078	8	+	27260156	HT29	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.5114632441287955	[300]	[477,655,625,351]	8	hSpCas9	negative selection	7288997
26770389	26770412	8	-	27260156	MHHES1	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.49128335727979816	[359]	[605,500,642,524]	8	hSpCas9	negative selection	7345965
26770362	26770385	8	+	27260156	MHHES1	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.42159022408011215	[1420]	[2516,2178,2310,1677]	7	hSpCas9	negative selection	7345966
26756748	26756771	8	+	27260156	MHHES1	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	-0.04270930745981616	[89]	[164,117,85,44]	-1	hSpCas9	negative selection	7345967
26766102	26766125	8	+	27260156	MHHES1	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.42133149134664194	[1549]	[2836,2608,2053,1969]	7	hSpCas9	negative selection	7410247
26766055	26766078	8	+	27260156	MHHES1	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.28596350570611123	[300]	[448,470,581,202]	5	hSpCas9	negative selection	7410248
26770389	26770412	8	-	27260156	MEWO	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.07559179493454998	[359]	[455,408,218]	1	hSpCas9	negative selection	7467216
26770362	26770385	8	+	27260156	MEWO	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.23307146575443638	[1420]	[1739,1484,1496]	5	hSpCas9	negative selection	7467217
26756748	26756771	8	+	27260156	MEWO	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.2159680019814756	[89]	[100,95,96]	5	hSpCas9	negative selection	7467218
26766102	26766125	8	+	27260156	MEWO	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.20834001675984748	[1549]	[1988,1594,1502]	4	hSpCas9	negative selection	7531498
26766055	26766078	8	+	27260156	MEWO	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.12750424020373385	[300]	[317,269,336]	3	hSpCas9	negative selection	7531499
26770389	26770412	8	-	27260156	LNCAPCLONEFGC	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.1795927196250362	[359]	[425,282,404,372]	3	hSpCas9	negative selection	7588467
26770362	26770385	8	+	27260156	LNCAPCLONEFGC	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.3338979379581153	[1420]	[1506,1473,1846,1705]	5	hSpCas9	negative selection	7588468
26756748	26756771	8	+	27260156	LNCAPCLONEFGC	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.54389661568031	[89]	[145,97,103,125]	8	hSpCas9	negative selection	7588469
26766102	26766125	8	+	27260156	LNCAPCLONEFGC	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.282638829835296	[1549]	[1744,1617,1762,1717]	4	hSpCas9	negative selection	7652749
26766055	26766078	8	+	27260156	LNCAPCLONEFGC	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.09384772371969252	[300]	[211,248,458,272]	1	hSpCas9	negative selection	7652750
26770389	26770412	8	-	27260156	PANC0327	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.17132267229219164	[359]	[594,379,276,204]	2	hSpCas9	negative selection	7709718
26770362	26770385	8	+	27260156	PANC0327	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.4220294612731783	[1420]	[2108,1558,1323,1822]	6	hSpCas9	negative selection	7709719
26756748	26756771	8	+	27260156	PANC0327	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.40311241740582626	[89]	[64,209,63,66]	6	hSpCas9	negative selection	7709720
26766102	26766125	8	+	27260156	PANC0327	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.52984823711517	[1549]	[2526,1430,1976,2131]	7	hSpCas9	negative selection	7774000
26766055	26766078	8	+	27260156	PANC0327	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.15348244005474598	[300]	[347,240,336,274]	2	hSpCas9	negative selection	7774001
26770389	26770412	8	-	27260156	NCIH2009	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.4489105017895639	[359]	[1103,633,403]	6	hSpCas9	negative selection	7830969
26770362	26770385	8	+	27260156	NCIH2009	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.29904184981294124	[1420]	[2915,2185,2319]	4	hSpCas9	negative selection	7830970
26756748	26756771	8	+	27260156	NCIH2009	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.7375874452510434	[89]	[249,132,254]	8	hSpCas9	negative selection	7830971
26766102	26766125	8	+	27260156	NCIH2009	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.8478346496697236	[1549]	[3633,3024,4990]	9	hSpCas9	negative selection	7895251
26766055	26766078	8	+	27260156	NCIH2009	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.11702912161855017	[300]	[512,300,374]	-2	hSpCas9	negative selection	7895252
26770389	26770412	8	-	27260156	NCIH1373	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.5233554822168885	[359]	[523,979,350,105]	5	hSpCas9	negative selection	7952220
26770362	26770385	8	+	27260156	NCIH1373	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.675062372488002	[1420]	[3287,1766,2400,769]	6	hSpCas9	negative selection	7952221
26756748	26756771	8	+	27260156	NCIH1373	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	1.0700336870310672	[89]	[299,215,166,45]	9	hSpCas9	negative selection	7952222
26766102	26766125	8	+	27260156	NCIH1373	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	1.199665101117506	[1549]	[6152,3368,3569,844]	9	hSpCas9	negative selection	8016502
26766055	26766078	8	+	27260156	NCIH1373	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.10060804420631031	[300]	[251,279,374,141]	1	hSpCas9	negative selection	8016503
26770389	26770412	8	-	27260156	PATU8902	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.665930619856616	[359]	[859,841,919,482]	7	hSpCas9	negative selection	8073471
26770362	26770385	8	+	27260156	PATU8902	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.7749158888606702	[1420]	[2712,3715,3112,4147]	7	hSpCas9	negative selection	8073472
26756748	26756771	8	+	27260156	PATU8902	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.004959582309484123	[89]	[211,101,9,217]	0	hSpCas9	negative selection	8073473
26766102	26766125	8	+	27260156	PATU8902	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.7585004551014478	[1549]	[3238,4985,2976,3548]	7	hSpCas9	negative selection	8137753
26766055	26766078	8	+	27260156	PATU8902	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.1306602664428721	[300]	[459,196,396,480]	-1	hSpCas9	negative selection	8137754
26770389	26770412	8	-	27260156	PANC1	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.09710140670454925	[359]	[224,457,168,327]	-1	hSpCas9	negative selection	8194722
26770362	26770385	8	+	27260156	PANC1	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.3059420675478006	[1420]	[1470,2058,1509,1144]	5	hSpCas9	negative selection	8194723
26756748	26756771	8	+	27260156	PANC1	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	1.0425552721883173	[89]	[94,159,133,233]	9	hSpCas9	negative selection	8194724
26766102	26766125	8	+	27260156	PANC1	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.74577271598146	[1549]	[2101,2894,2019,2043]	9	hSpCas9	negative selection	8259004
26766055	26766078	8	+	27260156	PANC1	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.426801984518258	[300]	[290,502,315,312]	7	hSpCas9	negative selection	8259005
26770389	26770412	8	-	27260156	PANC0813	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.7847473717271591	[359]	[730,740,660,776]	9	hSpCas9	negative selection	8315973
26770362	26770385	8	+	27260156	PANC0813	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.3799302151850874	[1420]	[2412,1829,2452,2020]	6	hSpCas9	negative selection	8315974
26756748	26756771	8	+	27260156	PANC0813	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	-0.26347903441617104	[89]	[148,42,81,83]	-4	hSpCas9	negative selection	8315975
26766102	26766125	8	+	27260156	PANC0813	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.6281245622848659	[1549]	[2918,2689,2749,2896]	8	hSpCas9	negative selection	8380255
26766055	26766078	8	+	27260156	PANC0813	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.0764276535230205	[300]	[356,274,255,447]	-1	hSpCas9	negative selection	8380256
26770389	26770412	8	-	27260156	RDES	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.3844825406217568	[359]	[221,325,381,357]	-6	hSpCas9	negative selection	8437224
26770362	26770385	8	+	27260156	RDES	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.09793200148294012	[1420]	[1405,1630,1851,2214]	1	hSpCas9	negative selection	8437225
26756748	26756771	8	+	27260156	RDES	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.4534025167261564	[89]	[168,139,140,98]	7	hSpCas9	negative selection	8437226
26766102	26766125	8	+	27260156	RDES	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.3627634410652094	[1549]	[2001,2150,2407,2673]	6	hSpCas9	negative selection	8501506
26766055	26766078	8	+	27260156	RDES	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.1481121849198198	[300]	[228,348,356,322]	-2	hSpCas9	negative selection	8501507
26770389	26770412	8	-	27260156	PC3	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.12018551687851275	[359]	[254,393,563,435]	2	hSpCas9	negative selection	8558475
26770362	26770385	8	+	27260156	PC3	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.20623347626703814	[1420]	[919,1586,2651,1958]	4	hSpCas9	negative selection	8558476
26756748	26756771	8	+	27260156	PC3	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	-0.033849887580061466	[89]	[51,84,144,98]	0	hSpCas9	negative selection	8558477
26766102	26766125	8	+	27260156	PC3	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	-0.019023275028875464	[1549]	[957,1365,2905,1516]	0	hSpCas9	negative selection	8622757
26766055	26766078	8	+	27260156	PC3	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.07362294185224771	[300]	[133,318,425,361]	-2	hSpCas9	negative selection	8622758
26770389	26770412	8	-	27260156	PATU8988T	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.8533348726288985	[359]	[681,329,391,1124]	9	hSpCas9	negative selection	8679726
26770362	26770385	8	+	27260156	PATU8988T	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.44129865624752296	[1420]	[1874,2154,1509,1956]	7	hSpCas9	negative selection	8679727
26756748	26756771	8	+	27260156	PATU8988T	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.5561573898891494	[89]	[66,131,262,40]	8	hSpCas9	negative selection	8679728
26766102	26766125	8	+	27260156	PATU8988T	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.4113239360826362	[1549]	[2030,2391,1928,1623]	7	hSpCas9	negative selection	8744008
26766055	26766078	8	+	27260156	PATU8988T	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.3960547450198797	[300]	[323,412,259,551]	6	hSpCas9	negative selection	8744009
26770389	26770412	8	-	27260156	T47D	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.01174220656974273	[359]	[478,316,433,471]	0	hSpCas9	negative selection	8800977
26770362	26770385	8	+	27260156	T47D	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.2164748986332261	[1420]	[1936,1849,1897,2017]	4	hSpCas9	negative selection	8800978
26756748	26756771	8	+	27260156	T47D	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.046626956150542576	[89]	[97,115,117,99]	1	hSpCas9	negative selection	8800979
26766102	26766125	8	+	27260156	T47D	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.36386632383677897	[1549]	[2477,2092,2284,2463]	7	hSpCas9	negative selection	8865259
26766055	26766078	8	+	27260156	T47D	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.27975869423441263	[300]	[470,423,436,368]	6	hSpCas9	negative selection	8865260
26770389	26770412	8	-	27260156	SU8686	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.7365711066541551	[359]	[484,557,703,657]	9	hSpCas9	negative selection	8922228
26770362	26770385	8	+	27260156	SU8686	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.3287096623635164	[1420]	[1618,1547,2083,1886]	5	hSpCas9	negative selection	8922229
26756748	26756771	8	+	27260156	SU8686	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.7801093146786735	[89]	[124,142,124,235]	9	hSpCas9	negative selection	8922230
26766102	26766125	8	+	27260156	SU8686	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.6296963352108857	[1549]	[2265,2388,2372,2494]	9	hSpCas9	negative selection	8986510
26766055	26766078	8	+	27260156	SU8686	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.011248963800128853	[300]	[208,301,348,339]	0	hSpCas9	negative selection	8986511
26770389	26770412	8	-	27260156	SKES1	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.10041514641171728	[359]	[459,341,280,278]	-2	hSpCas9	negative selection	9043479
26770362	26770385	8	+	27260156	SKES1	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.1902882470657199	[1420]	[2159,1339,1678,1346]	4	hSpCas9	negative selection	9043480
26756748	26756771	8	+	27260156	SKES1	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.3263032015421228	[89]	[143,95,71,136]	6	hSpCas9	negative selection	9043481
26766102	26766125	8	+	27260156	SKES1	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.3042261237418562	[1549]	[2328,1757,1802,1782]	6	hSpCas9	negative selection	9107761
26766055	26766078	8	+	27260156	SKES1	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.17249562479025543	[300]	[391,381,242,345]	4	hSpCas9	negative selection	9107762
26770389	26770412	8	-	27260156	TOV112D	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.41874374106928697	[359]	[434,798,350,417]	7	hSpCas9	negative selection	9164730
26770362	26770385	8	+	27260156	TOV112D	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.2164297328746172	[1420]	[1753,2004,1785,1174]	4	hSpCas9	negative selection	9164731
26756748	26756771	8	+	27260156	TOV112D	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.7849841509656563	[89]	[94,69,276,152]	9	hSpCas9	negative selection	9164732
26766102	26766125	8	+	27260156	TOV112D	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.1745441872421689	[1549]	[1791,1794,1598,1830]	3	hSpCas9	negative selection	9229012
26766055	26766078	8	+	27260156	TOV112D	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.447254685662012	[300]	[391,464,454,344]	8	hSpCas9	negative selection	9229013
26770389	26770412	8	-	27260156	TC71	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	0.07933515327997376	[359]	[377,406,392,456]	2	hSpCas9	negative selection	9285981
26770362	26770385	8	+	27260156	TC71	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.23038967130140198	[1420]	[1876,1880,1642,1746]	5	hSpCas9	negative selection	9285982
26756748	26756771	8	+	27260156	TC71	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.6434095292633899	[89]	[126,172,134,169]	9	hSpCas9	negative selection	9285983
26766102	26766125	8	+	27260156	TC71	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.2715265322835465	[1549]	[1912,1995,1826,2312]	6	hSpCas9	negative selection	9350263
26766055	26766078	8	+	27260156	TC71	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	0.36081772258598344	[300]	[381,369,484,418]	8	hSpCas9	negative selection	9350264
26770389	26770412	8	-	27260156	TC32	viability	GATCAAGAGAGACCTTCTACAGG	ADRA1A	ENSG00000120907	-0.4279293072265985	[359]	[275,82,378,342]	-7	hSpCas9	negative selection	9407232
26770362	26770385	8	+	27260156	TC32	viability	TTCACAAACGCCATCCGTCTTGG	ADRA1A	ENSG00000120907	0.058368987353649926	[1420]	[1258,1095,1772,1553]	1	hSpCas9	negative selection	9407233
26756748	26756771	8	+	27260156	TC32	viability	GGAAGCTGGCTTCATGTCATGGG	ADRA1A	ENSG00000120907	0.3104055062190376	[89]	[89,63,199,92]	5	hSpCas9	negative selection	9407234
26766102	26766125	8	+	27260156	TC32	viability	GATATGCTCTCTGCAATTCTTGG	ADRA1A	ENSG00000120907	0.20799690705515217	[1549]	[1592,1348,1965,1918]	4	hSpCas9	negative selection	9471514
26766055	26766078	8	+	27260156	TC32	viability	CATTCTGAACCCTTTCTCCACGG	ADRA1A	ENSG00000120907	-0.07837246581514545	[300]	[207,285,265,295]	-1	hSpCas9	negative selection	9471515
26756734	26756757	8	+	27869803	HPAFII	viability after 27 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	2.0689827291024443	[112]	[329,181,NaN]	9	hSpCas9	negative selection	9602303
26766058	26766081	8	+	27869803	HPAFII	viability after 27 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.7968501592211947	[169]	[181,132,NaN]	6	hSpCas9	negative selection	9602304
26770397	26770420	8	+	27869803	HPAFII	viability after 27 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.508178335277226	[135]	[70,32,NaN]	-4	hSpCas9	negative selection	9602305
26859132	26859155	8	-	27869803	HPAFII	viability after 27 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.47286198936143486	[381]	[395,180,NaN]	4	hSpCas9	negative selection	9602306
26864487	26864510	8	+	27869803	HPAFII	viability after 27 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-0.7821745183458337	[112]	[27,39,NaN]	-5	hSpCas9	negative selection	9602307
26864707	26864730	8	+	27869803	HPAFII	viability after 27 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.41568141584427054	[237]	[227,115,NaN]	3	hSpCas9	negative selection	9602308
26756734	26756757	8	+	27869803	HPAFII	viability after 15 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	1.3251068097623828	[112]	[278,319,NaN]	9	hSpCas9	negative selection	9684752
26766058	26766081	8	+	27869803	HPAFII	viability after 15 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.7379540833697409	[169]	[292,311,NaN]	8	hSpCas9	negative selection	9684753
26770397	26770420	8	+	27869803	HPAFII	viability after 15 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.5217131788848173	[135]	[197,41,NaN]	-5	hSpCas9	negative selection	9684754
26859132	26859155	8	-	27869803	HPAFII	viability after 15 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.5320575276577802	[381]	[732,506,NaN]	6	hSpCas9	negative selection	9684755
26864487	26864510	8	+	27869803	HPAFII	viability after 15 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-0.14762139879669323	[112]	[100,114,NaN]	-2	hSpCas9	negative selection	9684756
26864707	26864730	8	+	27869803	HPAFII	viability after 15 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.3053435719326389	[237]	[431,243,NaN]	3	hSpCas9	negative selection	9684757
26756734	26756757	8	+	27869803	ASPC1	viability after 36 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	0.5529907161298113	[326]	[127,269,111]	5	hSpCas9	negative selection	9767201
26766058	26766081	8	+	27869803	ASPC1	viability after 36 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.15432569067814667	[555]	[155,245,231]	1	hSpCas9	negative selection	9767202
26770397	26770420	8	+	27869803	ASPC1	viability after 36 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.27751427605732526	[479]	[236,124,77]	-3	hSpCas9	negative selection	9767203
26859132	26859155	8	-	27869803	ASPC1	viability after 36 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.18716190107631486	[840]	[276,192,482]	1	hSpCas9	negative selection	9767204
26864487	26864510	8	+	27869803	ASPC1	viability after 36 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-1.4481248843252854	[443]	[40,99,32]	-8	hSpCas9	negative selection	9767205
26864707	26864730	8	+	27869803	ASPC1	viability after 36 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.364091700154623	[703]	[537,239,217]	3	hSpCas9	negative selection	9767206
26756734	26756757	8	+	27869803	PATU8988S	viability after 35 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	-0.6078580255965571	[381]	[79,121,NaN]	-6	hSpCas9	negative selection	9849650
26766058	26766081	8	+	27869803	PATU8988S	viability after 35 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	-0.18930005807427586	[472]	[199,133,NaN]	-2	hSpCas9	negative selection	9849651
26770397	26770420	8	+	27869803	PATU8988S	viability after 35 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.03117795467850598	[401]	[133,182,NaN]	0	hSpCas9	negative selection	9849652
26859132	26859155	8	-	27869803	PATU8988S	viability after 35 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.1001774619147614	[771]	[236,429,NaN]	1	hSpCas9	negative selection	9849653
26864487	26864510	8	+	27869803	PATU8988S	viability after 35 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.7359921400386944	[301]	[237,166,NaN]	7	hSpCas9	negative selection	9849654
26864707	26864730	8	+	27869803	PATU8988S	viability after 35 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	1.2068218121593353	[516]	[539,420,NaN]	9	hSpCas9	negative selection	9849655
26756734	26756757	8	+	27869803	PATU8988S	viability after 31 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	-0.711204948363368	[381]	[85,101,NaN]	-6	hSpCas9	negative selection	9932099
26766058	26766081	8	+	27869803	PATU8988S	viability after 31 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	-0.15629930850339807	[472]	[170,166,NaN]	-2	hSpCas9	negative selection	9932100
26770397	26770420	8	+	27869803	PATU8988S	viability after 31 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.030380552100077562	[401]	[130,189,NaN]	0	hSpCas9	negative selection	9932101
26859132	26859155	8	-	27869803	PATU8988S	viability after 31 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.2499155586901768	[771]	[230,537,NaN]	3	hSpCas9	negative selection	9932102
26864487	26864510	8	+	27869803	PATU8988S	viability after 31 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	0.7567625532957865	[301]	[173,240,NaN]	8	hSpCas9	negative selection	9932103
26864707	26864730	8	+	27869803	PATU8988S	viability after 31 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.7655913464077807	[516]	[298,415,NaN]	8	hSpCas9	negative selection	9932104
26756734	26756757	8	+	27869803	HPAFII	viability after 35 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	2.285417615953179	[112]	[395,146,NaN]	9	hSpCas9	negative selection	10014548
26766058	26766081	8	+	27869803	HPAFII	viability after 35 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	1.641465275900389	[169]	[323,205,NaN]	9	hSpCas9	negative selection	10014549
26770397	26770420	8	+	27869803	HPAFII	viability after 35 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.8660257596988619	[135]	[57,14,NaN]	-5	hSpCas9	negative selection	10014550
26859132	26859155	8	-	27869803	HPAFII	viability after 35 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.3670871242828375	[381]	[263,232,NaN]	2	hSpCas9	negative selection	10014551
26864487	26864510	8	+	27869803	HPAFII	viability after 35 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-1.0961438656504638	[112]	[14,39,NaN]	-6	hSpCas9	negative selection	10014552
26864707	26864730	8	+	27869803	HPAFII	viability after 35 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	0.1736850234872219	[237]	[173,92,NaN]	1	hSpCas9	negative selection	10014553
26756734	26756757	8	+	27869803	HPAFII	viability after 31 days	AACAGTCGTGGACGGGAAGCTGG	ADRA1A	ENSG00000120907	2.1313175786169234	[112]	[385,159,NaN]	9	hSpCas9	negative selection	10096997
26766058	26766081	8	+	27869803	HPAFII	viability after 31 days	TCTGAACCCTTTCTCCACGGTGG	ADRA1A	ENSG00000120907	0.7989576154489887	[169]	[176,153,NaN]	6	hSpCas9	negative selection	10096998
26770397	26770420	8	+	27869803	HPAFII	viability after 31 days	AGGTCTCTCTTGATCCCACGGGG	ADRA1A	ENSG00000120907	-0.002643045837053881	[135]	[124,22,NaN]	0	hSpCas9	negative selection	10096999
26859132	26859155	8	-	27869803	HPAFII	viability after 31 days	TCTGCACTAGGCTGCGGGAGAGG	ADRA1A	ENSG00000120907	0.3126574928607273	[381]	[327,198,NaN]	2	hSpCas9	negative selection	10097000
26864487	26864510	8	+	27869803	HPAFII	viability after 31 days	GGGTCCAATGGATATGACCAGGG	ADRA1A	ENSG00000120907	-1.2273475307866373	[112]	[28,24,NaN]	-6	hSpCas9	negative selection	10097001
26864707	26864730	8	+	27869803	HPAFII	viability after 31 days	ACCTCGAAGATGGCGGAGAAGGG	ADRA1A	ENSG00000120907	-0.14258332635809126	[237]	[120,120,NaN]	-1	hSpCas9	negative selection	10097002
26864759	26864782	8	-	28162770	P31FUJ	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.4096457909675378	[163]	[255]	4	hSpCas9	negative selection	10107674
26770318	26770341	8	+	28162770	P31FUJ	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.49238622197547377	[368]	[609]	5	hSpCas9	negative selection	10107675
26864721	26864744	8	+	28162770	P31FUJ	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-2.0587728046393297	[38]	[10]	-8	hSpCas9	negative selection	10107676
26864670	26864693	8	+	28162770	P31FUJ	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.5282311497136578	[320]	[543]	6	hSpCas9	negative selection	10107677
26864600	26864623	8	+	28162770	P31FUJ	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	0.46053645735156945	[93]	[151]	5	hSpCas9	negative selection	10107678
26864557	26864580	8	+	28162770	P31FUJ	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.41784196792797546	[457]	[718]	4	hSpCas9	negative selection	10107679
26864339	26864362	8	-	28162770	P31FUJ	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	0.015456848739016857	[228]	[271]	0	hSpCas9	negative selection	10107680
26864320	26864343	8	-	28162770	P31FUJ	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-0.19098202871975167	[169]	[174]	-2	hSpCas9	negative selection	10107681
26770481	26770504	8	-	28162770	P31FUJ	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	0.29891827502979823	[183]	[265]	3	hSpCas9	negative selection	10107682
26770427	26770450	8	-	28162770	P31FUJ	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.858192327806214	[191]	[408]	8	hSpCas9	negative selection	10107683
26864759	26864782	8	-	28162770	TF1	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[199]	1	hSpCas9	negative selection	10277040
26770318	26770341	8	+	28162770	TF1	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[355]	1	hSpCas9	negative selection	10277041
26864721	26864744	8	+	28162770	TF1	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10277042
26864670	26864693	8	+	28162770	TF1	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[266]	1	hSpCas9	negative selection	10277043
26864600	26864623	8	+	28162770	TF1	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10277044
26864557	26864580	8	+	28162770	TF1	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10277045
26864339	26864362	8	-	28162770	TF1	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10277046
26864320	26864343	8	-	28162770	TF1	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10277047
26770481	26770504	8	-	28162770	TF1	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10277048
26770427	26770450	8	-	28162770	TF1	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	NaN	[NaN]	[229]	1	hSpCas9	negative selection	10277049
26864759	26864782	8	-	28162770	SKM1	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.6925714748077527	[41]	[119]	6	hSpCas9	negative selection	10446406
26770318	26770341	8	+	28162770	SKM1	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.3120911975652773	[76]	[168]	3	hSpCas9	negative selection	10446407
26864721	26864744	8	+	28162770	SKM1	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-1.4069641987431618	[8]	[5]	-7	hSpCas9	negative selection	10446408
26864670	26864693	8	+	28162770	SKM1	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.4120536408400224	[87]	[206]	4	hSpCas9	negative selection	10446409
26864600	26864623	8	+	28162770	SKM1	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-1.1057946640225969	[27]	[22]	-7	hSpCas9	negative selection	10446410
26864557	26864580	8	+	28162770	SKM1	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.5710094949268394	[98]	[259]	5	hSpCas9	negative selection	10446411
26864339	26864362	8	-	28162770	SKM1	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-0.6062730069665684	[61]	[71]	-5	hSpCas9	negative selection	10446412
26864320	26864343	8	-	28162770	SKM1	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-0.27451390271951204	[38]	[56]	-2	hSpCas9	negative selection	10446413
26770481	26770504	8	-	28162770	SKM1	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	0.09737984176970996	[45]	[86]	0	hSpCas9	negative selection	10446414
26770427	26770450	8	-	28162770	SKM1	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	-0.4131961524546764	[57]	[76]	-3	hSpCas9	negative selection	10446415
26864759	26864782	8	-	28162770	SKM1	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.6925714748077527	[41]	[119]	6	hSpCas9	negative selection	10615772
26770318	26770341	8	+	28162770	SKM1	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.3120911975652773	[76]	[168]	3	hSpCas9	negative selection	10615773
26864721	26864744	8	+	28162770	SKM1	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-1.4069641987431618	[8]	[5]	-7	hSpCas9	negative selection	10615774
26864670	26864693	8	+	28162770	SKM1	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.4120536408400224	[87]	[206]	4	hSpCas9	negative selection	10615775
26864600	26864623	8	+	28162770	SKM1	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-1.1057946640225969	[27]	[22]	-7	hSpCas9	negative selection	10615776
26864557	26864580	8	+	28162770	SKM1	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.5710094949268394	[98]	[259]	5	hSpCas9	negative selection	10615777
26864339	26864362	8	-	28162770	SKM1	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-0.6062730069665684	[61]	[71]	-5	hSpCas9	negative selection	10615778
26864320	26864343	8	-	28162770	SKM1	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-0.27451390271951204	[38]	[56]	-2	hSpCas9	negative selection	10615779
26770481	26770504	8	-	28162770	SKM1	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	0.09737984176970996	[45]	[86]	0	hSpCas9	negative selection	10615780
26770427	26770450	8	-	28162770	SKM1	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	-0.4131961524546764	[57]	[76]	-3	hSpCas9	negative selection	10615781
26864759	26864782	8	-	28162770	PL21	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.3143106344086314	[169]	[91]	2	hSpCas9	negative selection	10785138
26770318	26770341	8	+	28162770	PL21	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.2932490188808017	[284]	[151]	2	hSpCas9	negative selection	10785139
26864721	26864744	8	+	28162770	PL21	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-0.9697853869529922	[26]	[5]	-6	hSpCas9	negative selection	10785140
26864670	26864693	8	+	28162770	PL21	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	-0.1026566202198459	[411]	[166]	0	hSpCas9	negative selection	10785141
26864600	26864623	8	+	28162770	PL21	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-0.6790059906362943	[102]	[27]	-5	hSpCas9	negative selection	10785142
26864557	26864580	8	+	28162770	PL21	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.434604868126343	[373]	[219]	4	hSpCas9	negative selection	10785143
26864339	26864362	8	-	28162770	PL21	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-0.6642052861531136	[141]	[38]	-4	hSpCas9	negative selection	10785144
26864320	26864343	8	-	28162770	PL21	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-2.887323226761019	[101]	[5]	-9	hSpCas9	negative selection	10785145
26770481	26770504	8	-	28162770	PL21	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	-0.02464732198751056	[200]	[85]	0	hSpCas9	negative selection	10785146
26770427	26770450	8	-	28162770	PL21	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.2698485863007246	[201]	[105]	2	hSpCas9	negative selection	10785147
26864759	26864782	8	-	28162770	P31FUJ	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.4096457909675378	[163]	[255]	4	hSpCas9	negative selection	10954504
26770318	26770341	8	+	28162770	P31FUJ	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.49238622197547377	[368]	[609]	5	hSpCas9	negative selection	10954505
26864721	26864744	8	+	28162770	P31FUJ	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-2.0587728046393297	[38]	[10]	-8	hSpCas9	negative selection	10954506
26864670	26864693	8	+	28162770	P31FUJ	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.5282311497136578	[320]	[543]	6	hSpCas9	negative selection	10954507
26864600	26864623	8	+	28162770	P31FUJ	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	0.46053645735156945	[93]	[151]	5	hSpCas9	negative selection	10954508
26864557	26864580	8	+	28162770	P31FUJ	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.41784196792797546	[457]	[718]	4	hSpCas9	negative selection	10954509
26864339	26864362	8	-	28162770	P31FUJ	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	0.015456848739016857	[228]	[271]	0	hSpCas9	negative selection	10954510
26864320	26864343	8	-	28162770	P31FUJ	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-0.19098202871975167	[169]	[174]	-2	hSpCas9	negative selection	10954511
26770481	26770504	8	-	28162770	P31FUJ	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	0.29891827502979823	[183]	[265]	3	hSpCas9	negative selection	10954512
26770427	26770450	8	-	28162770	P31FUJ	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.858192327806214	[191]	[408]	8	hSpCas9	negative selection	10954513
26864759	26864782	8	-	28162770	OCIAML5	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.03141942040957779	[57]	[106]	0	hSpCas9	negative selection	11123870
26770318	26770341	8	+	28162770	OCIAML5	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.35587469417491047	[128]	[297]	3	hSpCas9	negative selection	11123871
26864721	26864744	8	+	28162770	OCIAML5	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-2.437029071585153	[14]	[4]	-8	hSpCas9	negative selection	11123872
26864670	26864693	8	+	28162770	OCIAML5	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	-0.14904830862112822	[171]	[279]	-1	hSpCas9	negative selection	11123873
26864600	26864623	8	+	28162770	OCIAML5	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-2.5525062890050894	[64]	[19]	-8	hSpCas9	negative selection	11123874
26864557	26864580	8	+	28162770	OCIAML5	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.40732005795465254	[197]	[473]	3	hSpCas9	negative selection	11123875
26864339	26864362	8	-	28162770	OCIAML5	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-0.626646456829981	[135]	[158]	-4	hSpCas9	negative selection	11123876
26864320	26864343	8	-	28162770	OCIAML5	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-1.4476763157846617	[67]	[44]	-7	hSpCas9	negative selection	11123877
26770481	26770504	8	-	28162770	OCIAML5	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	-0.6363378798085599	[123]	[143]	-4	hSpCas9	negative selection	11123878
26770427	26770450	8	-	28162770	OCIAML5	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.220502055086648	[125]	[264]	1	hSpCas9	negative selection	11123879
26864759	26864782	8	-	28162770	EOL1	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	-0.4775506720008112	[295]	[111]	-4	hSpCas9	negative selection	11293236
26770318	26770341	8	+	28162770	EOL1	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	-0.878838248284124	[362]	[103]	-6	hSpCas9	negative selection	11293237
26864721	26864744	8	+	28162770	EOL1	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-1.9234491349844154	[35]	[4]	-8	hSpCas9	negative selection	11293238
26864670	26864693	8	+	28162770	EOL1	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.2811484441126766	[591]	[378]	2	hSpCas9	negative selection	11293239
26864600	26864623	8	+	28162770	EOL1	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-1.265783440533615	[177]	[38]	-7	hSpCas9	negative selection	11293240
26864557	26864580	8	+	28162770	EOL1	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	-0.10911994119486046	[736]	[359]	-1	hSpCas9	negative selection	11293241
26864339	26864362	8	-	28162770	EOL1	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	0.809582057450014	[234]	[216]	7	hSpCas9	negative selection	11293242
26864320	26864343	8	-	28162770	EOL1	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-1.1285635648890278	[165]	[39]	-6	hSpCas9	negative selection	11293243
26770481	26770504	8	-	28162770	EOL1	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	-0.9278950400156077	[194]	[53]	-6	hSpCas9	negative selection	11293244
26770427	26770450	8	-	28162770	EOL1	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.9638606955953606	[180]	[185]	8	hSpCas9	negative selection	11293245
26864759	26864782	8	-	28162770	MOLM13	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	-0.32531505216999174	[278]	[160]	-2	hSpCas9	negative selection	11462602
26770318	26770341	8	+	28162770	MOLM13	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	-1.1502399831117769	[395]	[128]	-6	hSpCas9	negative selection	11462603
26864721	26864744	8	+	28162770	MOLM13	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-2.0764311346792312	[34]	[5]	-7	hSpCas9	negative selection	11462604
26864670	26864693	8	+	28162770	MOLM13	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.8372392427762125	[400]	[517]	6	hSpCas9	negative selection	11462605
26864600	26864623	8	+	28162770	MOLM13	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	0.9472861266198009	[136]	[190]	7	hSpCas9	negative selection	11462606
26864557	26864580	8	+	28162770	MOLM13	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.16461134376488096	[537]	[435]	1	hSpCas9	negative selection	11462607
26864339	26864362	8	-	28162770	MOLM13	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-2.8911917117602495	[235]	[22]	-8	hSpCas9	negative selection	11462608
26864320	26864343	8	-	28162770	MOLM13	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-0.2579356550164271	[171]	[103]	-1	hSpCas9	negative selection	11462609
26770481	26770504	8	-	28162770	MOLM13	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	0.15366154533879856	[326]	[262]	1	hSpCas9	negative selection	11462610
26770427	26770450	8	-	28162770	MOLM13	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	-0.08272161438580028	[248]	[169]	0	hSpCas9	negative selection	11462611
26864759	26864782	8	-	28162770	HEL	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.40868349313832897	[206]	[175]	3	hSpCas9	negative selection	11631968
26770318	26770341	8	+	28162770	HEL	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.2494719553927322	[284]	[216]	2	hSpCas9	negative selection	11631969
26864721	26864744	8	+	28162770	HEL	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-4.783525922701741	[42]	[0]	-9	hSpCas9	negative selection	11631970
26864670	26864693	8	+	28162770	HEL	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	1.1213551270537054	[454]	[633]	8	hSpCas9	negative selection	11631971
26864600	26864623	8	+	28162770	HEL	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-0.15016493375970652	[148]	[85]	-1	hSpCas9	negative selection	11631972
26864557	26864580	8	+	28162770	HEL	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	1.0339702968498676	[442]	[580]	8	hSpCas9	negative selection	11631973
26864339	26864362	8	-	28162770	HEL	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-1.1937624357167635	[249]	[69]	-6	hSpCas9	negative selection	11631974
26864320	26864343	8	-	28162770	HEL	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	0.3262651672051028	[131]	[105]	2	hSpCas9	negative selection	11631975
26770481	26770504	8	-	28162770	HEL	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	-0.07346820199905195	[229]	[139]	0	hSpCas9	negative selection	11631976
26770427	26770450	8	-	28162770	HEL	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.2527923136843434	[189]	[144]	2	hSpCas9	negative selection	11631977
26864759	26864782	8	-	28162770	MV411	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	-0.2954608903718368	[168]	[115]	-2	hSpCas9	negative selection	11801334
26770318	26770341	8	+	28162770	MV411	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	-0.22356876064129533	[218]	[157]	-2	hSpCas9	negative selection	11801335
26864721	26864744	8	+	28162770	MV411	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	0.6803969580588816	[19]	[26]	6	hSpCas9	negative selection	11801336
26864670	26864693	8	+	28162770	MV411	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.5923966143254785	[347]	[441]	5	hSpCas9	negative selection	11801337
26864600	26864623	8	+	28162770	MV411	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-0.09873809035126424	[74]	[58]	-1	hSpCas9	negative selection	11801338
26864557	26864580	8	+	28162770	MV411	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.2581242295800227	[268]	[270]	2	hSpCas9	negative selection	11801339
26864339	26864362	8	-	28162770	MV411	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-0.8260246111582459	[140]	[66]	-5	hSpCas9	negative selection	11801340
26864320	26864343	8	-	28162770	MV411	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	1.8230318689697365	[102]	[306]	9	hSpCas9	negative selection	11801341
26770481	26770504	8	-	28162770	MV411	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	0.6135654495806726	[89]	[115]	5	hSpCas9	negative selection	11801342
26770427	26770450	8	-	28162770	MV411	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	1.2650316107975135	[162]	[329]	9	hSpCas9	negative selection	11801343
26864759	26864782	8	-	28162770	MONOMAC1	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	0.5096709260139718	[105]	[172]	5	hSpCas9	negative selection	11970700
26770318	26770341	8	+	28162770	MONOMAC1	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	-0.3430518706650059	[186]	[168]	-3	hSpCas9	negative selection	11970701
26864721	26864744	8	+	28162770	MONOMAC1	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-2.518964941946916	[19]	[3]	-9	hSpCas9	negative selection	11970702
26864670	26864693	8	+	28162770	MONOMAC1	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.1787206645574787	[241]	[313]	1	hSpCas9	negative selection	11970703
26864600	26864623	8	+	28162770	MONOMAC1	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	0.8991784681997494	[57]	[123]	8	hSpCas9	negative selection	11970704
26864557	26864580	8	+	28162770	MONOMAC1	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	-0.2798371521120665	[250]	[236]	-2	hSpCas9	negative selection	11970705
26864339	26864362	8	-	28162770	MONOMAC1	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	0.6311968046739664	[97]	[173]	6	hSpCas9	negative selection	11970706
26864320	26864343	8	-	28162770	MONOMAC1	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-0.052646937724379006	[56]	[62]	0	hSpCas9	negative selection	11970707
26770481	26770504	8	-	28162770	MONOMAC1	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	-0.3595898598455135	[121]	[108]	-3	hSpCas9	negative selection	11970708
26770427	26770450	8	-	28162770	MONOMAC1	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.5539356051005317	[81]	[137]	5	hSpCas9	negative selection	11970709
26864759	26864782	8	-	28162770	OCIAML2	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	1.225363987867739	[24]	[323]	9	hSpCas9	negative selection	12140066
26770318	26770341	8	+	28162770	OCIAML2	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	-0.5122089289935606	[43]	[170]	-4	hSpCas9	negative selection	12140067
26864721	26864744	8	+	28162770	OCIAML2	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-1.4117361361885927	[11]	[24]	-7	hSpCas9	negative selection	12140068
26864670	26864693	8	+	28162770	OCIAML2	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.540774938030088	[62]	[507]	5	hSpCas9	negative selection	12140069
26864600	26864623	8	+	28162770	OCIAML2	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	0.9888017933951361	[10]	[120]	8	hSpCas9	negative selection	12140070
26864557	26864580	8	+	28162770	OCIAML2	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.7365280823991263	[50]	[470]	7	hSpCas9	negative selection	12140071
26864339	26864362	8	-	28162770	OCIAML2	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-0.7336642310759551	[38]	[129]	-5	hSpCas9	negative selection	12140072
26864320	26864343	8	-	28162770	OCIAML2	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	-0.07470114891102209	[18]	[99]	0	hSpCas9	negative selection	12140073
26770481	26770504	8	-	28162770	OCIAML2	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	0.2054805635371903	[22]	[146]	2	hSpCas9	negative selection	12140074
26770427	26770450	8	-	28162770	OCIAML2	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	-0.30588506290552897	[30]	[138]	-2	hSpCas9	negative selection	12140075
26864759	26864782	8	-	28162770	OCIAML3	viability	CTACATCGTCAACCTGGCGGTGG	ADRA1A	ENSG00000120907	1.950312875899647	[26]	[314]	9	hSpCas9	negative selection	12309432
26770318	26770341	8	+	28162770	OCIAML3	viability	GTAATCCTGGCAGATCCACGGGG	ADRA1A	ENSG00000120907	0.18621115179592684	[68]	[236]	1	hSpCas9	negative selection	12309433
26864721	26864744	8	+	28162770	OCIAML3	viability	GGAGAAGGGCAGCACCGTGGAGG	ADRA1A	ENSG00000120907	-0.09150729979497996	[5]	[16]	0	hSpCas9	negative selection	12309434
26864670	26864693	8	+	28162770	OCIAML3	viability	GTTGCAGAAGACCCTGCCGAAGG	ADRA1A	ENSG00000120907	0.3559516771762412	[87]	[339]	3	hSpCas9	negative selection	12309435
26864600	26864623	8	+	28162770	OCIAML3	viability	GGTCGATGGAGATGATGCAGAGG	ADRA1A	ENSG00000120907	-1.1465486633529418	[32]	[44]	-7	hSpCas9	negative selection	12309436
26864557	26864580	8	+	28162770	OCIAML3	viability	ACGATGGTTGGGTAGCGCAGCGG	ADRA1A	ENSG00000120907	0.04158093346696079	[111]	[347]	0	hSpCas9	negative selection	12309437
26864339	26864362	8	-	28162770	OCIAML3	viability	GTACTGCCGCGTCTACGTGGTGG	ADRA1A	ENSG00000120907	-0.7143018740418751	[49]	[91]	-5	hSpCas9	negative selection	12309438
26864320	26864343	8	-	28162770	OCIAML3	viability	GTGGCCAAGAGGGAGAGCCGGGG	ADRA1A	ENSG00000120907	0.10901062191870531	[42]	[139]	1	hSpCas9	negative selection	12309439
26770481	26770504	8	-	28162770	OCIAML3	viability	GCAGTCTTCCAAACATGCCCTGG	ADRA1A	ENSG00000120907	-0.410785816268393	[47]	[108]	-3	hSpCas9	negative selection	12309440
26770427	26770450	8	-	28162770	OCIAML3	viability	GGAAGGGCAACACAAGGACATGG	ADRA1A	ENSG00000120907	0.11270013274936234	[52]	[172]	1	hSpCas9	negative selection	12309441