Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:147
• Symbol:ADRA1B
• Description:adrenoceptor alpha 1B

DataSource: http://genomecrispr.dkfz.de/#!/results/ADRA1B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
159917318	159917341	5	-	26472758	Jiyoye	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	-0.21057705433295237	[355]	[231]	-1	hSpCas9	negative selection	3429
159917199	159917222	5	-	26472758	Jiyoye	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	-1.0181304532267972	[93]	[34]	-6	hSpCas9	negative selection	3430
159917423	159917446	5	-	26472758	Jiyoye	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	1.158147833665959	[122]	[206]	7	hSpCas9	negative selection	3431
159917443	159917466	5	-	26472758	Jiyoye	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.8192290223458958	[120]	[160]	6	hSpCas9	negative selection	3432
159917598	159917621	5	+	26472758	Jiyoye	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	-0.9798477416033738	[169]	[64]	-6	hSpCas9	negative selection	3433
159916997	159917020	5	-	26472758	Jiyoye	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	0.547353039554134	[48]	[53]	4	hSpCas9	negative selection	3434
159917016	159917039	5	+	26472758	Jiyoye	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	1.0075679227966357	[61]	[93]	6	hSpCas9	negative selection	3435
159917516	159917539	5	-	26472758	Jiyoye	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-6.100619258692823	[90]	[0]	-9	hSpCas9	negative selection	3436
159917066	159917089	5	-	26472758	Jiyoye	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.08343371624657991	[198]	[158]	0	hSpCas9	negative selection	3437
159917174	159917197	5	-	26472758	Jiyoye	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	-0.9519057117989549	[58]	[22]	-6	hSpCas9	negative selection	3438
159917318	159917341	5	-	26472758	KBM7	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.6968181079017688	[820,1013]	[819,611]	7	hSpCas9	negative selection	194547
159917199	159917222	5	-	26472758	KBM7	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	-0.3701690502282172	[341,225]	[126,78]	-3	hSpCas9	negative selection	194548
159917423	159917446	5	-	26472758	KBM7	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.15846083896804858	[658,540]	[374,257]	1	hSpCas9	negative selection	194549
159917443	159917466	5	-	26472758	KBM7	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.3419678993082622	[737,523]	[392,351]	3	hSpCas9	negative selection	194550
159917598	159917621	5	+	26472758	KBM7	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.3065568731579576	[386,285]	[313,85]	3	hSpCas9	negative selection	194551
159916997	159917020	5	-	26472758	KBM7	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	0.3268663283496458	[217,102]	[69,110]	3	hSpCas9	negative selection	194552
159917016	159917039	5	+	26472758	KBM7	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.7484178414076278	[426,304]	[302,269]	7	hSpCas9	negative selection	194553
159917516	159917539	5	-	26472758	KBM7	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-2.3175219841049213	[225,383]	[16,40]	-9	hSpCas9	negative selection	194554
159917066	159917089	5	-	26472758	KBM7	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.36869792390429107	[551,719]	[275,497]	4	hSpCas9	negative selection	194555
159917174	159917197	5	-	26472758	KBM7	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	-0.5293971942961404	[232,229]	[127,28]	-5	hSpCas9	negative selection	194556
159917318	159917341	5	-	26472758	Raji	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.2888880557107949	[454]	[128]	2	hSpCas9	negative selection	385665
159917199	159917222	5	-	26472758	Raji	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	0.044373737847798966	[116]	[27]	0	hSpCas9	negative selection	385666
159917423	159917446	5	-	26472758	Raji	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.6016843131770966	[300]	[105]	5	hSpCas9	negative selection	385667
159917443	159917466	5	-	26472758	Raji	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.8114933013877603	[301]	[122]	7	hSpCas9	negative selection	385668
159917598	159917621	5	+	26472758	Raji	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.5224210346524434	[116]	[38]	5	hSpCas9	negative selection	385669
159916997	159917020	5	-	26472758	Raji	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-0.6792128265172073	[68]	[9]	-5	hSpCas9	negative selection	385670
159917016	159917039	5	+	26472758	Raji	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.31220332726209754	[235]	[67]	3	hSpCas9	negative selection	385671
159917516	159917539	5	-	26472758	Raji	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-2.1150088859628484	[223]	[11]	-8	hSpCas9	negative selection	385672
159917066	159917089	5	-	26472758	Raji	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.6048831948444164	[254]	[89]	6	hSpCas9	negative selection	385673
159917174	159917197	5	-	26472758	Raji	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	0.2759831393493444	[120]	[33]	2	hSpCas9	negative selection	385674
159917318	159917341	5	-	26472758	K562	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.8570015511908251	[844]	[1291]	7	hSpCas9	negative selection	576783
159917199	159917222	5	-	26472758	K562	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	1.0389496093664674	[112]	[195]	8	hSpCas9	negative selection	576784
159917423	159917446	5	-	26472758	K562	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.9819766827692807	[486]	[811]	8	hSpCas9	negative selection	576785
159917443	159917466	5	-	26472758	K562	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.6688113919969936	[537]	[721]	5	hSpCas9	negative selection	576786
159917598	159917621	5	+	26472758	K562	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.34938828726798954	[211]	[227]	2	hSpCas9	negative selection	576787
159916997	159917020	5	-	26472758	K562	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-0.551222773827367	[183]	[105]	-3	hSpCas9	negative selection	576788
159917016	159917039	5	+	26472758	K562	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.324145920137181	[263]	[278]	2	hSpCas9	negative selection	576789
159917516	159917539	5	-	26472758	K562	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-2.4274518382778743	[324]	[50]	-8	hSpCas9	negative selection	576790
159917066	159917089	5	-	26472758	K562	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.9836021470824717	[519]	[867]	8	hSpCas9	negative selection	576791
159917174	159917197	5	-	26472758	K562	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	-1.097973469780631	[212]	[83]	-6	hSpCas9	negative selection	576792
159917178	159917201	5	-	26627737	DLD1	viability	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.02792702245152473	[541]	[96,206,209]	0	hSpCas9	negative selection	827840
159917363	159917386	5	+	26627737	DLD1	viability	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	0.37076413975484823	[394]	[145,152,176]	4	hSpCas9	negative selection	827841
159917390	159917413	5	-	26627737	DLD1	viability	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	-0.7162611417933935	[682]	[192,110,90]	-6	hSpCas9	negative selection	827842
159917463	159917486	5	+	26627737	DLD1	viability	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.8120465987553829	[405]	[239,264,172]	7	hSpCas9	negative selection	827843
159971902	159971925	5	-	26627737	DLD1	viability	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-0.6334105959558304	[312]	[60,138,1]	-6	hSpCas9	negative selection	827846
159972241	159972264	5	-	26627737	DLD1	viability	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	-0.03127854674416475	[255]	[73,116,49]	0	hSpCas9	negative selection	827847
159917178	159917201	5	-	26627737	GBM cells	viability after 5 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.47708720994420284	[212]	[127,189]	7	hSpCas9	negative selection	910155
159917363	159917386	5	+	26627737	GBM cells	viability after 5 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.816205016982272	[283]	[83,88]	-8	hSpCas9	negative selection	910156
159917390	159917413	5	-	26627737	GBM cells	viability after 5 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.39404496537777606	[253]	[157,199]	6	hSpCas9	negative selection	910157
159917463	159917486	5	+	26627737	GBM cells	viability after 5 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.4691172183344272	[261]	[140,247]	7	hSpCas9	negative selection	910158
159971902	159971925	5	-	26627737	GBM cells	viability after 5 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	0.2146897427914527	[93]	[80,35]	3	hSpCas9	negative selection	910161
159972241	159972264	5	-	26627737	GBM cells	viability after 5 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	0.0833384460231128	[87]	[52,46]	1	hSpCas9	negative selection	910162
159917178	159917201	5	-	26627737	GBM cells	viability after 13 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.7458292112606413	[212]	[211,178]	8	hSpCas9	negative selection	992470
159917363	159917386	5	+	26627737	GBM cells	viability after 13 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.8000384458432374	[283]	[125,57]	-7	hSpCas9	negative selection	992471
159917390	159917413	5	-	26627737	GBM cells	viability after 13 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.25336173848939236	[253]	[230,109]	3	hSpCas9	negative selection	992472
159917463	159917486	5	+	26627737	GBM cells	viability after 13 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.6097424213324291	[261]	[206,224]	7	hSpCas9	negative selection	992473
159971902	159971925	5	-	26627737	GBM cells	viability after 13 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-0.1881959258459842	[93]	[57,33]	-2	hSpCas9	negative selection	992476
159972241	159972264	5	-	26627737	GBM cells	viability after 13 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	-0.39099573709492486	[87]	[31,39]	-5	hSpCas9	negative selection	992477
159917178	159917201	5	-	26627737	GBM cells	viability after 21 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.41864581195876704	[212]	[173,136]	4	hSpCas9	negative selection	1074785
159917363	159917386	5	+	26627737	GBM cells	viability after 21 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.8640886688074361	[283]	[101,68]	-6	hSpCas9	negative selection	1074786
159917390	159917413	5	-	26627737	GBM cells	viability after 21 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.12665867717467555	[253]	[146,153]	1	hSpCas9	negative selection	1074787
159917463	159917486	5	+	26627737	GBM cells	viability after 21 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	1.1173911499683638	[261]	[324,293]	9	hSpCas9	negative selection	1074788
159971902	159971925	5	-	26627737	GBM cells	viability after 21 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-2.9494627901963475	[93]	[3,8]	-9	hSpCas9	negative selection	1074791
159972241	159972264	5	-	26627737	GBM cells	viability after 21 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	-0.27907459445262517	[87]	[29,47]	-3	hSpCas9	negative selection	1074792
159917178	159917201	5	-	26627737	RPE1	viability after 9 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-1.3612087314798411	[1489]	[95,291]	-7	hSpCas9	negative selection	1157100
159917363	159917386	5	+	26627737	RPE1	viability after 9 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.865215294268532	[770]	[98,23]	-8	hSpCas9	negative selection	1157101
159917390	159917413	5	-	26627737	RPE1	viability after 9 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	1.2088220985454736	[547]	[334,475]	7	hSpCas9	negative selection	1157102
159917463	159917486	5	+	26627737	RPE1	viability after 9 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	-0.37492886757285804	[1979]	[422,548]	-3	hSpCas9	negative selection	1157103
159971902	159971925	5	-	26627737	RPE1	viability after 9 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	7.461232823760884	[0]	[45,66]	9	hSpCas9	negative selection	1157106
159972241	159972264	5	-	26627737	RPE1	viability after 9 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	0.9697782612786398	[218]	[25,273]	6	hSpCas9	negative selection	1157107
159917178	159917201	5	-	26627737	RPE1	viability after 12 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-1.4591186583650524	[1489]	[80,213]	-7	hSpCas9	negative selection	1239415
159917363	159917386	5	+	26627737	RPE1	viability after 12 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.0334101584349487	[770]	[124,75]	-6	hSpCas9	negative selection	1239416
159917390	159917413	5	-	26627737	RPE1	viability after 12 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	1.1770862979079932	[547]	[312,353]	7	hSpCas9	negative selection	1239417
159917463	159917486	5	+	26627737	RPE1	viability after 12 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	-0.31091608252494174	[1979]	[524,326]	-2	hSpCas9	negative selection	1239418
159971902	159971925	5	-	26627737	RPE1	viability after 12 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	9.020084974509325	[0]	[104,175]	9	hSpCas9	negative selection	1239421
159972241	159972264	5	-	26627737	RPE1	viability after 12 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	0.8441806633142414	[218]	[109,100]	5	hSpCas9	negative selection	1239422
159917178	159917201	5	-	26627737	RPE1	viability after 15 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-1.1358650066097906	[1489]	[230,153]	-6	hSpCas9	negative selection	1321730
159917363	159917386	5	+	26627737	RPE1	viability after 15 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.245595561232847	[770]	[64,117]	-6	hSpCas9	negative selection	1321731
159917390	159917413	5	-	26627737	RPE1	viability after 15 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	1.1722676099519573	[547]	[469,232]	6	hSpCas9	negative selection	1321732
159917463	159917486	5	+	26627737	RPE1	viability after 15 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	-1.1092031958700859	[1979]	[223,293]	-6	hSpCas9	negative selection	1321733
159971902	159971925	5	-	26627737	RPE1	viability after 15 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	8.155824939469833	[0]	[126,35]	9	hSpCas9	negative selection	1321736
159972241	159972264	5	-	26627737	RPE1	viability after 15 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	1.282532075014132	[218]	[82,215]	7	hSpCas9	negative selection	1321737
159917178	159917201	5	-	26627737	RPE1	viability after 18 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-1.1997875269066003	[1489]	[161,188]	-6	hSpCas9	negative selection	1404045
159917363	159917386	5	+	26627737	RPE1	viability after 18 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.142117262718715	[770]	[43,147]	-6	hSpCas9	negative selection	1404046
159917390	159917413	5	-	26627737	RPE1	viability after 18 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.7016003341829886	[547]	[269,208]	4	hSpCas9	negative selection	1404047
159917463	159917486	5	+	26627737	RPE1	viability after 18 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	-0.659160015285222	[1979]	[421,248]	-4	hSpCas9	negative selection	1404048
159971902	159971925	5	-	26627737	RPE1	viability after 18 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	7.22706821957829	[0]	[52,26]	9	hSpCas9	negative selection	1404051
159972241	159972264	5	-	26627737	RPE1	viability after 18 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	1.1980643143726726	[218]	[50,225]	6	hSpCas9	negative selection	1404052
159917178	159917201	5	-	26627737	HeLa	viability after 8 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-0.07804090061967303	[461]	[193,259,122]	0	hSpCas9	negative selection	1486360
159917363	159917386	5	+	26627737	HeLa	viability after 8 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.3849283277612408	[283]	[8,24,95]	-8	hSpCas9	negative selection	1486361
159917390	159917413	5	-	26627737	HeLa	viability after 8 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	1.4083615203748105	[218]	[259,300,202]	8	hSpCas9	negative selection	1486362
159917463	159917486	5	+	26627737	HeLa	viability after 8 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.3274805086810405	[329]	[254,165,138]	3	hSpCas9	negative selection	1486363
159971902	159971925	5	-	26627737	HeLa	viability after 8 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	0.44999255681682326	[24]	[0,2,35]	4	hSpCas9	negative selection	1486366
159972241	159972264	5	-	26627737	HeLa	viability after 8 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	7.759502727126844	[0]	[85,25,163]	9	hSpCas9	negative selection	1486367
159917178	159917201	5	-	26627737	HeLa	viability after 12 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-0.00028256404787627143	[461]	[204,219,144]	0	hSpCas9	negative selection	1568675
159917363	159917386	5	+	26627737	HeLa	viability after 12 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.1769076607410138	[283]	[0,25,129]	-8	hSpCas9	negative selection	1568676
159917390	159917413	5	-	26627737	HeLa	viability after 12 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.8133083467591022	[218]	[191,121,167]	6	hSpCas9	negative selection	1568677
159917463	159917486	5	+	26627737	HeLa	viability after 12 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.38281613130904846	[329]	[152,231,141]	3	hSpCas9	negative selection	1568678
159971902	159971925	5	-	26627737	HeLa	viability after 12 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	2.551688302902498	[24]	[121,55,5]	9	hSpCas9	negative selection	1568681
159972241	159972264	5	-	26627737	HeLa	viability after 12 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	5.87383989933809	[0]	[31,32,6]	9	hSpCas9	negative selection	1568682
159917178	159917201	5	-	26627737	HeLa	viability after 15 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.29382940539630487	[461]	[463,86,129]	2	hSpCas9	negative selection	1650990
159917363	159917386	5	+	26627737	HeLa	viability after 15 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.47733464997724917	[283]	[31,71,150]	-4	hSpCas9	negative selection	1650991
159917390	159917413	5	-	26627737	HeLa	viability after 15 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.4971854099160029	[218]	[62,120,199]	4	hSpCas9	negative selection	1650992
159917463	159917486	5	+	26627737	HeLa	viability after 15 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.6734668293383532	[329]	[128,238,280]	5	hSpCas9	negative selection	1650993
159971902	159971925	5	-	26627737	HeLa	viability after 15 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	1.226706022922937	[24]	[0,55,13]	8	hSpCas9	negative selection	1650996
159972241	159972264	5	-	26627737	HeLa	viability after 15 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	8.060976650467149	[0]	[93,163,64]	9	hSpCas9	negative selection	1650997
159917178	159917201	5	-	26627737	HeLa	viability after 18 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.3556641588949625	[461]	[326,76,129]	3	hSpCas9	negative selection	1733305
159917363	159917386	5	+	26627737	HeLa	viability after 18 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.4244217346851932	[283]	[23,63,150]	-4	hSpCas9	negative selection	1733306
159917390	159917413	5	-	26627737	HeLa	viability after 18 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.4946852005872629	[218]	[41,99,199]	4	hSpCas9	negative selection	1733307
159917463	159917486	5	+	26627737	HeLa	viability after 18 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.6759801003723203	[329]	[91,191,280]	5	hSpCas9	negative selection	1733308
159971902	159971925	5	-	26627737	HeLa	viability after 18 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	1.227748508819535	[24]	[0,45,13]	8	hSpCas9	negative selection	1733311
159972241	159972264	5	-	26627737	HeLa	viability after 18 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	7.9874479429198475	[0]	[57,128,64]	9	hSpCas9	negative selection	1733312
159917178	159917201	5	-	26627737	HCT116	viability after 6 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	1.5246328180160282	[599]	[505,141]	7	hSpCas9	negative selection	1815620
159917363	159917386	5	+	26627737	HCT116	viability after 6 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.4148538725000983	[361]	[52,36]	-2	hSpCas9	negative selection	1815621
159917390	159917413	5	-	26627737	HCT116	viability after 6 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	1.2648061131677577	[276]	[132,88]	6	hSpCas9	negative selection	1815622
159917463	159917486	5	+	26627737	HCT116	viability after 6 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	1.9604779398589458	[512]	[144,406]	8	hSpCas9	negative selection	1815623
159971902	159971925	5	-	26627737	HCT116	viability after 6 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-0.847159113770993	[359]	[73,7]	-5	hSpCas9	negative selection	1815626
159972241	159972264	5	-	26627737	HCT116	viability after 6 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	3.167370442866425	[236]	[899,22]	9	hSpCas9	negative selection	1815627
159917178	159917201	5	-	26627737	HCT116	viability after 8 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-0.06781368724389719	[403]	[174,206,253]	0	hSpCas9	negative selection	1897935
159917363	159917386	5	+	26627737	HCT116	viability after 8 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	0.32024015379189097	[178]	[102,135,129]	3	hSpCas9	negative selection	1897936
159917390	159917413	5	-	26627737	HCT116	viability after 8 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.14958526570995226	[238]	[151,110,174]	1	hSpCas9	negative selection	1897937
159917463	159917486	5	+	26627737	HCT116	viability after 8 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.7265208492239201	[210]	[206,144,224]	7	hSpCas9	negative selection	1897938
159971902	159971925	5	-	26627737	HCT116	viability after 8 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	0.47416336182405927	[89]	[68,95,41]	5	hSpCas9	negative selection	1897941
159972241	159972264	5	-	26627737	HCT116	viability after 8 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	0.15612880123813722	[119]	[74,66,78]	1	hSpCas9	negative selection	1897942
159917178	159917201	5	-	26627737	HCT116	viability after 9 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.2711849357538054	[599]	[294,112]	2	hSpCas9	negative selection	1980250
159917363	159917386	5	+	26627737	HCT116	viability after 9 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.2284550924062956	[361]	[14,61]	-7	hSpCas9	negative selection	1980251
159917390	159917413	5	-	26627737	HCT116	viability after 9 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	1.08537159837802	[276]	[228,99]	7	hSpCas9	negative selection	1980252
159917463	159917486	5	+	26627737	HCT116	viability after 9 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.06821344327971746	[512]	[70,200]	0	hSpCas9	negative selection	1980253
159971902	159971925	5	-	26627737	HCT116	viability after 9 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-4.719501053554325	[359]	[6,0]	-9	hSpCas9	negative selection	1980256
159972241	159972264	5	-	26627737	HCT116	viability after 9 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	0.8558475917892476	[236]	[56,159]	6	hSpCas9	negative selection	1980257
159917178	159917201	5	-	26627737	HCT116	viability after 12 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.02731368750677532	[403]	[246,198,199]	0	hSpCas9	negative selection	2062565
159917363	159917386	5	+	26627737	HCT116	viability after 12 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	0.3248343765466727	[178]	[214,37,89]	3	hSpCas9	negative selection	2062566
159917390	159917413	5	-	26627737	HCT116	viability after 12 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.6703857080020257	[238]	[252,157,182]	6	hSpCas9	negative selection	2062567
159917463	159917486	5	+	26627737	HCT116	viability after 12 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	1.354812756947498	[210]	[417,117,298]	9	hSpCas9	negative selection	2062568
159971902	159971925	5	-	26627737	HCT116	viability after 12 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	0.3184771179446495	[89]	[40,119,18]	3	hSpCas9	negative selection	2062571
159972241	159972264	5	-	26627737	HCT116	viability after 12 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	0.7616615377083059	[119]	[176,81,54]	6	hSpCas9	negative selection	2062572
159917178	159917201	5	-	26627737	HCT116	viability after 15 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.20108474389147413	[403]	[296,253,252]	2	hSpCas9	negative selection	2144880
159917363	159917386	5	+	26627737	HCT116	viability after 15 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.6321364293428409	[178]	[25,70,1]	-9	hSpCas9	negative selection	2144881
159917390	159917413	5	-	26627737	HCT116	viability after 15 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.4660447143121951	[238]	[233,134,204]	4	hSpCas9	negative selection	2144882
159917463	159917486	5	+	26627737	HCT116	viability after 15 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	1.1267511702150455	[210]	[364,172,267]	8	hSpCas9	negative selection	2144883
159971902	159971925	5	-	26627737	HCT116	viability after 15 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-0.07344328254607357	[89]	[82,61,6]	0	hSpCas9	negative selection	2144886
159972241	159972264	5	-	26627737	HCT116	viability after 15 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	0.9182203098493222	[119]	[210,97,91]	7	hSpCas9	negative selection	2144887
159917178	159917201	5	-	26627737	HCT116	viability after 18 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.4128357165089245	[403]	[236,329,205]	3	hSpCas9	negative selection	2227195
159917363	159917386	5	+	26627737	HCT116	viability after 18 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.3645984371062267	[178]	[9,75,10]	-8	hSpCas9	negative selection	2227196
159917390	159917413	5	-	26627737	HCT116	viability after 18 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.6749395255662972	[238]	[138,180,235]	5	hSpCas9	negative selection	2227197
159917463	159917486	5	+	26627737	HCT116	viability after 18 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	1.1035939604406466	[210]	[220,120,326]	8	hSpCas9	negative selection	2227198
159971902	159971925	5	-	26627737	HCT116	viability after 18 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	0.40010075532207057	[89]	[103,48,17]	3	hSpCas9	negative selection	2227201
159972241	159972264	5	-	26627737	HCT116	viability after 18 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	1.2183580146876727	[119]	[129,170,99]	8	hSpCas9	negative selection	2227202
159916899	159916922	5	+	24336569	HL60	viability	CTCTAAGATGAATCCCGACCTGG	ADRA1B	ENSG00000170214	-3.060999998069181	[279]	[70]	-9	hSpCas9	negative selection	2246812
159916906	159916929	5	+	24336569	HL60	viability	ATGAATCCCGACCTGGACACCGG	ADRA1B	ENSG00000170214	-0.12163237143264471	[782]	[1522]	-1	hSpCas9	negative selection	2246813
159916912	159916935	5	-	24336569	HL60	viability	TTGTGGCCGGTGTCCAGGTCGGG	ADRA1B	ENSG00000170214	1.6493492665557148	[46]	[311]	9	hSpCas9	negative selection	2246814
159916917	159916940	5	-	24336569	HL60	viability	ATGTGTTGTGGCCGGTGTCCAGG	ADRA1B	ENSG00000170214	1.2722602132786274	[358]	[1834]	8	hSpCas9	negative selection	2246815
159916925	159916948	5	-	24336569	HL60	viability	AGGTGCTGATGTGTTGTGGCCGG	ADRA1B	ENSG00000170214	0.5974915380739407	[509]	[1632]	5	hSpCas9	negative selection	2246816
159916934	159916957	5	+	24336569	HL60	viability	ACACATCAGCACCTGCCCACTGG	ADRA1B	ENSG00000170214	0.377967518008401	[731]	[2012]	3	hSpCas9	negative selection	2246817
159916987	159917010	5	-	24336569	HL60	viability	GAGTTGCTCGAGGTCTGGTTGGG	ADRA1B	ENSG00000170214	0.4349466304301367	[509]	[1458]	4	hSpCas9	negative selection	2246818
159916992	159917015	5	-	24336569	HL60	viability	GTGTGGAGTTGCTCGAGGTCTGG	ADRA1B	ENSG00000170214	1.5549349553188199	[224]	[1398]	9	hSpCas9	negative selection	2246819
159916997	159917020	5	-	24336569	HL60	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-1.0646883878780695	[341]	[345]	-7	hSpCas9	negative selection	2246820
159917019	159917042	5	-	24336569	HL60	viability	TGGCCCTGGTGATGTCCAGCTGG	ADRA1B	ENSG00000170214	-0.06968693285254268	[731]	[1475]	0	hSpCas9	negative selection	2246821
159916899	159916922	5	+	24336569	KBM7	viability	CTCTAAGATGAATCCCGACCTGG	ADRA1B	ENSG00000170214	0.3721382265264407	[165]	[585]	3	hSpCas9	negative selection	2313989
159916906	159916929	5	+	24336569	KBM7	viability	ATGAATCCCGACCTGGACACCGG	ADRA1B	ENSG00000170214	-0.24579346475001762	[825]	[1899]	-2	hSpCas9	negative selection	2313990
159916912	159916935	5	-	24336569	KBM7	viability	TTGTGGCCGGTGTCCAGGTCGGG	ADRA1B	ENSG00000170214	-0.9666074270852623	[138]	[193]	-6	hSpCas9	negative selection	2313991
159916917	159916940	5	-	24336569	KBM7	viability	ATGTGTTGTGGCCGGTGTCCAGG	ADRA1B	ENSG00000170214	-0.027487107668517363	[462]	[1238]	0	hSpCas9	negative selection	2313992
159916925	159916948	5	-	24336569	KBM7	viability	AGGTGCTGATGTGTTGTGGCCGG	ADRA1B	ENSG00000170214	-0.4908416598015495	[676]	[1313]	-4	hSpCas9	negative selection	2313993
159916934	159916957	5	+	24336569	KBM7	viability	ACACATCAGCACCTGCCCACTGG	ADRA1B	ENSG00000170214	0.13738330417227373	[705]	[2117]	1	hSpCas9	negative selection	2313994
159916987	159917010	5	-	24336569	KBM7	viability	GAGTTGCTCGAGGTCTGGTTGGG	ADRA1B	ENSG00000170214	0.751297178589559	[295]	[1358]	6	hSpCas9	negative selection	2313995
159916992	159917015	5	-	24336569	KBM7	viability	GTGTGGAGTTGCTCGAGGTCTGG	ADRA1B	ENSG00000170214	1.309444049958577	[174]	[1182]	9	hSpCas9	negative selection	2313996
159916997	159917020	5	-	24336569	KBM7	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	1.1468935234547464	[125]	[760]	8	hSpCas9	negative selection	2313997
159917019	159917042	5	-	24336569	KBM7	viability	TGGCCCTGGTGATGTCCAGCTGG	ADRA1B	ENSG00000170214	0.6830863744462028	[297]	[1304]	6	hSpCas9	negative selection	2313998
159945299	159945322	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAATGGCGCAATCTGGG	ADRA1B	ENSG00000170214	-1.2636642880956617	[40,137]	[5,8]	-7	dCas9-VP64	positive selection	2392498
159970845	159970868	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGCACTGCACTCCAGCCTGGG	ADRA1B	ENSG00000170214	0.14919512582895444	[137,141]	[31,35]	0	dCas9-VP64	positive selection	2409512
159947078	159947101	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATCTGTAATCCCAGCACTTTGG	ADRA1B	ENSG00000170214	0.936948372456865	[294,1308]	[29,678]	4	dCas9-VP64	positive selection	2456832
159945299	159945322	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAATGGCGCAATCTGGG	ADRA1B	ENSG00000170214	0.9509983420270334	[172,98]	[152,23]	6	dCas9-VP64	positive selection	2487753
159970845	159970868	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGCACTGCACTCCAGCCTGGG	ADRA1B	ENSG00000170214	0.26947116138715255	[117,96]	[23,58]	2	dCas9-VP64	positive selection	2504767
159947078	159947101	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATCTGTAATCCCAGCACTTTGG	ADRA1B	ENSG00000170214	-0.19682723409902197	[171,197]	[36,65]	-2	dCas9-VP64	positive selection	2552087
159917017	159917040	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	-0.2897734696217396	[3,3]	[3,1]	-4	hSpCas9	positive selection	2969197
159917577	159917600	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTGGCCACTATATAGACACGG	ADRA1B	ENSG00000170214	0.1969103666099054	[4,4]	[3,4]	4	hSpCas9	positive selection	2969198
159917547	159917570	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGACTAGAATGACCGCCAGAGGG	ADRA1B	ENSG00000170214	-0.12405228064366566	[4,4]	[4,2]	-2	hSpCas9	positive selection	2969199
159917273	159917296	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGCAGCACAGGACATCCACGG	ADRA1B	ENSG00000170214	0.1230988164853361	[5,4]	[4,4]	2	hSpCas9	positive selection	2969200
159917017	159917040	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.16463414866574344	[3,3]	[1,3]	3	hSpCas9	positive selection	3037055
159917577	159917600	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTGGCCACTATATAGACACGG	ADRA1B	ENSG00000170214	0.328110864344367	[4,4]	[3,4]	6	hSpCas9	positive selection	3037056
159917547	159917570	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGACTAGAATGACCGCCAGAGGG	ADRA1B	ENSG00000170214	0.17826070091563084	[4,4]	[3,3]	3	hSpCas9	positive selection	3037057
159917273	159917296	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGCAGCACAGGACATCCACGG	ADRA1B	ENSG00000170214	0.23293703944373845	[5,5]	[4,3]	4	hSpCas9	positive selection	3037058
159917471	159917494		-	24336571	A375	resistance to PLX after 7 days	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-0.22751516775314573	[30,34]	[29,26]	-7	hSpCas9	positive selection	3107207
159971998	159972021		+	24336571	A375	resistance to PLX after 7 days	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.020037558252732457	[27,22]	[24,26]	0	hSpCas9	positive selection	3107217
159917571	159917594		+	24336571	A375	resistance to PLX after 7 days	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.04238038839058156	[6,6]	[6,6]	-1	hSpCas9	positive selection	3107225
159917471	159917494		-	24336571	A375	resistance to PLX after 14 days	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.23600599791230192	[39,35]	[21,18]	2	hSpCas9	positive selection	3165000
159971998	159972021		+	24336571	A375	resistance to PLX after 14 days	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.07443041964786268	[30,27]	[14,12]	0	hSpCas9	positive selection	3165010
159917571	159917594		+	24336571	A375	resistance to PLX after 14 days	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.7336940229989901	[8,6]	[1,1]	-8	hSpCas9	positive selection	3165018
159917471	159917494		-	24336571	A375	viability after 7 days	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.16061390194492153	[30]	[30,34]	2	hSpCas9	negative selection	3222793
159971998	159972021		+	24336571	A375	viability after 7 days	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.7108536363064557	[15]	[27,22]	9	hSpCas9	negative selection	3222803
159917571	159917594		+	24336571	A375	viability after 7 days	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.06218485053571243	[6]	[6,6]	0	hSpCas9	negative selection	3222811
159917471	159917494		-	24336571	A375	viability after 14 days	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.349459335299666	[30]	[39,35]	4	hSpCas9	negative selection	3280586
159971998	159972021		+	24336571	A375	viability after 14 days	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.9240515473989788	[15]	[30,27]	9	hSpCas9	negative selection	3280596
159917571	159917594		+	24336571	A375	viability after 14 days	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.23543302485448248	[6]	[8,6]	3	hSpCas9	negative selection	3280604
159971998	159972021	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	-0.6932535090011166	[228,265]	[0,0]	-5	hSpCas9	positive selection	3335779
159972097	159972120	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	1.6437714474891185	[42,54]	[0,0]	6	hSpCas9	positive selection	3335780
159917571	159917594	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.7603484544662901	[62,117]	[0,0]	3	hSpCas9	positive selection	3335781
159917833	159917856	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	-1.9714924790500457	[599,599]	[0,0]	-9	hSpCas9	positive selection	3355028
159917471	159917494	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-1.181465641132426	[346,346]	[0,0]	-7	hSpCas9	positive selection	3355029
159917423	159917446	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	1.3265888738829488	[60,60]	[0,0]	6	hSpCas9	positive selection	3355030
159917016	159917039	5	+	26780180	HT29	viability (Avana library 4 designs)	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.233591874295676	[]	[]	0	hSpCas9	negative selection	3405261
159917577	159917600	5	-	26780180	HT29	viability (Avana library 4 designs)	TCTTGGCCACTATATAGACACGG	ADRA1B	ENSG00000170214	0.110244171554358	[]	[]	0	hSpCas9	negative selection	3405262
159917547	159917570	5	-	26780180	HT29	viability (Avana library 4 designs)	TGACTAGAATGACCGCCAGAGGG	ADRA1B	ENSG00000170214	0.199672095870671	[]	[]	0	hSpCas9	negative selection	3405263
159917273	159917296	5	-	26780180	HT29	viability (Avana library 4 designs)	TGTGCAGCACAGGACATCCACGG	ADRA1B	ENSG00000170214	0.40144965289614	[]	[]	1	hSpCas9	negative selection	3405264
159917016	159917039	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	-1.98681215909032	[]	[]	-2	hSpCas9	negative selection	3477186
159917547	159917570	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGACTAGAATGACCGCCAGAGGG	ADRA1B	ENSG00000170214	2.32515482567023	[]	[]	3	hSpCas9	negative selection	3477187
159917577	159917600	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGGCCACTATATAGACACGG	ADRA1B	ENSG00000170214	-0.473556152582208	[]	[]	0	hSpCas9	negative selection	3477188
159917273	159917296	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGCAGCACAGGACATCCACGG	ADRA1B	ENSG00000170214	0.752118269843323	[]	[]	1	hSpCas9	negative selection	3477189
159917598	159917621	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	-1.9766741672434	[]	[]	-2	hSpCas9	negative selection	3477190
159917660	159917683	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCTTGGAATGGATCCTCAGGG	ADRA1B	ENSG00000170214	-0.545155191633579	[]	[]	0	hSpCas9	negative selection	3477191
159917016	159917039	5	+	26780180	A375	viability (Avana lentiGuide)	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	-1.06673218815102	[]	[]	-2	hSpCas9	negative selection	3585845
159917547	159917570	5	-	26780180	A375	viability (Avana lentiGuide)	TGACTAGAATGACCGCCAGAGGG	ADRA1B	ENSG00000170214	-0.485763913551539	[]	[]	0	hSpCas9	negative selection	3585846
159917577	159917600	5	-	26780180	A375	viability (Avana lentiGuide)	TCTTGGCCACTATATAGACACGG	ADRA1B	ENSG00000170214	-2.23692225356871	[]	[]	-4	hSpCas9	negative selection	3585847
159917273	159917296	5	-	26780180	A375	viability (Avana lentiGuide)	TGTGCAGCACAGGACATCCACGG	ADRA1B	ENSG00000170214	-1.86711406835576	[]	[]	-3	hSpCas9	negative selection	3585848
159917598	159917621	5	+	26780180	A375	viability (Avana lentiGuide)	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	1.22913203844524	[]	[]	1	hSpCas9	negative selection	3585849
159917660	159917683	5	-	26780180	A375	viability (Avana lentiGuide)	GTTCTTGGAATGGATCCTCAGGG	ADRA1B	ENSG00000170214	-2.35086404100373	[]	[]	-4	hSpCas9	negative selection	3585850
159917016	159917039	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	-0.023098416792947787	[4]	[4,3]	0	hSpCas9	positive selection	3694504
159917547	159917570	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACTAGAATGACCGCCAGAGGG	ADRA1B	ENSG00000170214	-0.024152233960529734	[6]	[6,5]	0	hSpCas9	positive selection	3694505
159917577	159917600	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGGCCACTATATAGACACGG	ADRA1B	ENSG00000170214	-0.34531446668085986	[6]	[4,4]	-5	hSpCas9	positive selection	3694506
159917273	159917296	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGCAGCACAGGACATCCACGG	ADRA1B	ENSG00000170214	0.19611990019845266	[5]	[6,6]	5	hSpCas9	positive selection	3694507
159917598	159917621	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	-0.22118286674267226	[4]	[4,2]	-3	hSpCas9	positive selection	3694508
159917660	159917683	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCTTGGAATGGATCCTCAGGG	ADRA1B	ENSG00000170214	-0.10683873182902198	[6]	[6,6]	-2	hSpCas9	positive selection	3694509
159917016	159917039	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.3424170887438296	[5]	[6,5]	8	hSpCas9	positive selection	3803111
159917547	159917570	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACTAGAATGACCGCCAGAGGG	ADRA1B	ENSG00000170214	-0.01344829431246497	[6]	[5,5]	0	hSpCas9	positive selection	3803112
159917577	159917600	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGGCCACTATATAGACACGG	ADRA1B	ENSG00000170214	0.30081958109227935	[6]	[6,6]	8	hSpCas9	positive selection	3803113
159917273	159917296	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGCAGCACAGGACATCCACGG	ADRA1B	ENSG00000170214	0.3361253365843867	[6]	[7,7]	8	hSpCas9	positive selection	3803114
159917598	159917621	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.414112395550842	[5]	[6,5]	9	hSpCas9	positive selection	3803115
159917660	159917683	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCTTGGAATGGATCCTCAGGG	ADRA1B	ENSG00000170214	0.24582741160882365	[6]	[7,6]	6	hSpCas9	positive selection	3803116
159972097	159972120	5	-	26780180	A375	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	1.29272827588902	[]	[]	7	hSpCas9	negative selection	3911574
159917423	159917446	5	-	26780180	A375	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.778527229399707	[]	[]	3	hSpCas9	negative selection	3911575
159917471	159917494	5	-	26780180	A375	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.785395124119015	[]	[]	3	hSpCas9	negative selection	3911576
159971998	159972021	5	+	26780180	A375	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.256084540916442	[]	[]	0	hSpCas9	negative selection	3911577
159917571	159917594	5	+	26780180	A375	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	1.5793361938661	[]	[]	8	hSpCas9	negative selection	3911578
159917833	159917856	5	+	26780180	A375	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.278821826702418	[]	[]	0	hSpCas9	negative selection	3911579
159972097	159972120	5	-	26780180	HT29	viability (GeCKOv2 library)	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.927001109414306	[]	[]	4	hSpCas9	negative selection	4019540
159917423	159917446	5	-	26780180	HT29	viability (GeCKOv2 library)	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	1.15074868456473	[]	[]	5	hSpCas9	negative selection	4019541
159917471	159917494	5	-	26780180	HT29	viability (GeCKOv2 library)	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.468062236018893	[]	[]	1	hSpCas9	negative selection	4019542
159971998	159972021	5	+	26780180	HT29	viability (GeCKOv2 library)	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	-0.145185024240505	[]	[]	-4	hSpCas9	negative selection	4019543
159917571	159917594	5	+	26780180	HT29	viability (GeCKOv2 library)	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.885802006478888	[]	[]	4	hSpCas9	negative selection	4019544
159917833	159917856	5	+	26780180	HT29	viability (GeCKOv2 library)	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	-0.192209501627567	[]	[]	-5	hSpCas9	negative selection	4019545
159917471	159917494	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.22414010555294	[4]	[3,4]	5	hSpCas9	positive selection	4129446
159971998	159972021	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.2987298905262602	[4]	[3,3]	7	hSpCas9	positive selection	4129457
159917571	159917594	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.2609685686042357	[2]	[1,0]	-6	hSpCas9	positive selection	4129468
159917471	159917494	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.051658428898271325	[5]	[3,3,1,0]	0	hSpCas9	positive selection	4193468
159971998	159972021	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.38590222600175955	[5]	[4,3,5,0]	3	hSpCas9	positive selection	4193479
159917571	159917594	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.14709727125588284	[2]	[1,0,0,0]	-2	hSpCas9	positive selection	4193490
159971998	159972021	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.2646839871911599	[3]	[4,2]	5	hSpCas9	positive selection	4254743
159972097	159972120	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.33996481956307123	[2]	[2,1]	7	hSpCas9	positive selection	4254744
159917571	159917594	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.3057839545351819	[2]	[1,0]	-6	hSpCas9	positive selection	4254745
159917833	159917856	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.17595498396771275	[4]	[4,2]	3	hSpCas9	positive selection	4319025
159917471	159917494	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.31080986544088157	[3]	[3,4]	6	hSpCas9	positive selection	4319026
159917423	159917446	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.2697670303083858	[1]	[1,0]	-5	hSpCas9	positive selection	4319027
159917204	159917226	5	-	27760321	OCIAML3	viability	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	-0.3535829918231688	[478,371]	[232,291]	-4	hSpCas9	negative selection	4376511
159917310	159917332	5	-	27760321	OCIAML3	viability	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	-0.13278280437303414	[575,491]	[301,480]	-1	hSpCas9	negative selection	4376512
159917464	159917486	5	+	27760321	OCIAML3	viability	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.39066253344624824	[534,428]	[417,586]	5	hSpCas9	negative selection	4376513
159917548	159917570	5	-	27760321	OCIAML3	viability	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	0.09799967617381314	[395,335]	[224,409]	1	hSpCas9	negative selection	4376514
159917671	159917693	5	+	27760321	OCIAML3	viability	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.02643294952318931	[317,264]	[179,297]	0	hSpCas9	negative selection	4376515
159917204	159917226	5	-	27760321	OCIAML2	viability	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	-0.3746658807223419	[478,371]	[235,299]	-4	hSpCas9	negative selection	4459974
159917310	159917332	5	-	27760321	OCIAML2	viability	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.6837564742251393	[575,491]	[588,826]	8	hSpCas9	negative selection	4459975
159917464	159917486	5	+	27760321	OCIAML2	viability	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.4052664469160697	[534,428]	[389,675]	5	hSpCas9	negative selection	4459976
159917548	159917570	5	-	27760321	OCIAML2	viability	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	-0.4155569699922201	[395,335]	[168,289]	-5	hSpCas9	negative selection	4459977
159917671	159917693	5	+	27760321	OCIAML2	viability	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.8721096318888902	[317,264]	[352,530]	9	hSpCas9	negative selection	4459978
159917204	159917226	5	-	27760321	MV411	viability	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	-1.133070340312937	[478,371]	[33,266]	-6	hSpCas9	negative selection	4543437
159917310	159917332	5	-	27760321	MV411	viability	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.42739013544317206	[575,491]	[214,858]	3	hSpCas9	negative selection	4543438
159917464	159917486	5	+	27760321	MV411	viability	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.6598284476256839	[534,428]	[300,797]	5	hSpCas9	negative selection	4543439
159917548	159917570	5	-	27760321	MV411	viability	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	-0.4199215855598671	[395,335]	[69,344]	-3	hSpCas9	negative selection	4543440
159917671	159917693	5	+	27760321	MV411	viability	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	1.8209834838122099	[317,264]	[452,1012]	9	hSpCas9	negative selection	4543441
159917204	159917226	5	-	27760321	HL60	viability	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	0.5242969396040178	[478,371]	[591,394]	6	hSpCas9	negative selection	4626900
159917310	159917332	5	-	27760321	HL60	viability	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.4194614841376203	[575,491]	[632,526]	5	hSpCas9	negative selection	4626901
159917464	159917486	5	+	27760321	HL60	viability	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	-0.0710363289254026	[534,428]	[460,278]	-1	hSpCas9	negative selection	4626902
159917548	159917570	5	-	27760321	HL60	viability	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	-0.4043009771078459	[395,335]	[245,202]	-4	hSpCas9	negative selection	4626903
159917671	159917693	5	+	27760321	HL60	viability	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.9343973179594773	[317,264]	[292,622]	8	hSpCas9	negative selection	4626904
159917204	159917226	5	-	27760321	HT1080	viability	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	-0.1302333477773963	[371,289]	[161,74]	0	hSpCas9	negative selection	4710363
159917310	159917332	5	-	27760321	HT1080	viability	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.36058409626999566	[491,383]	[308,130]	1	hSpCas9	negative selection	4710364
159917464	159917486	5	+	27760321	HT1080	viability	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	1.1218775418411806	[428,334]	[387,268]	6	hSpCas9	negative selection	4710365
159917548	159917570	5	-	27760321	HT1080	viability	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	0.217184101907429	[335,261]	[126,150]	1	hSpCas9	negative selection	4710366
159917671	159917693	5	+	27760321	HT1080	viability	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.42699792098632094	[264,206]	[18,243]	2	hSpCas9	negative selection	4710367
159917204	159917226	5	-	27760321	HT29	viability after 7 days	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	0.29394059818773277	[371,289]	[270,620,632]	4	hSpCas9	negative selection	4793826
159917310	159917332	5	-	27760321	HT29	viability after 7 days	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.23312451457652517	[491,383]	[867,733,419]	3	hSpCas9	negative selection	4793827
159917464	159917486	5	+	27760321	HT29	viability after 7 days	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.6825802220900032	[428,334]	[736,1101,525]	9	hSpCas9	negative selection	4793828
159917548	159917570	5	-	27760321	HT29	viability after 7 days	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	-0.05013955862670011	[335,261]	[370,362,378]	0	hSpCas9	negative selection	4793829
159917671	159917693	5	+	27760321	HT29	viability after 7 days	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	-0.009306976265477163	[264,206]	[372,263,277]	0	hSpCas9	negative selection	4793830
159917204	159917226	5	-	27760321	HT29	viability after 25 days	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	-0.02133419513959739	[371,289]	[372,401,338]	0	hSpCas9	negative selection	4877289
159917310	159917332	5	-	27760321	HT29	viability after 25 days	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.46174453581160013	[491,383]	[845,626,571]	5	hSpCas9	negative selection	4877290
159917464	159917486	5	+	27760321	HT29	viability after 25 days	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	1.0458908869937695	[428,334]	[713,1189,799]	9	hSpCas9	negative selection	4877291
159917548	159917570	5	-	27760321	HT29	viability after 25 days	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	0.6140992745724785	[335,261]	[457,558,558]	7	hSpCas9	negative selection	4877292
159917671	159917693	5	+	27760321	HT29	viability after 25 days	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.4692644073223331	[264,206]	[274,544,297]	5	hSpCas9	negative selection	4877293
159917204	159917226	5	-	27760321	HT29	viability after 22 days	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	0.08836395515859978	[371,289]	[386,311,522]	0	hSpCas9	negative selection	4960752
159917310	159917332	5	-	27760321	HT29	viability after 22 days	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	-0.04671859595687072	[491,383]	[262,594,619]	0	hSpCas9	negative selection	4960753
159917464	159917486	5	+	27760321	HT29	viability after 22 days	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	1.2713919354271408	[428,334]	[1059,1416,717]	9	hSpCas9	negative selection	4960754
159917548	159917570	5	-	27760321	HT29	viability after 22 days	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	0.37163343034499224	[335,261]	[406,451,483]	4	hSpCas9	negative selection	4960755
159917671	159917693	5	+	27760321	HT29	viability after 22 days	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.2514785645605804	[264,206]	[193,345,438]	2	hSpCas9	negative selection	4960756
159917204	159917226	5	-	27760321	HT29	viability after 19 days	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	0.24656380005926457	[371,289]	[238,691,395]	2	hSpCas9	negative selection	5044215
159917310	159917332	5	-	27760321	HT29	viability after 19 days	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.5382691306110101	[491,383]	[641,616,906]	5	hSpCas9	negative selection	5044216
159917464	159917486	5	+	27760321	HT29	viability after 19 days	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.9971499168685727	[428,334]	[523,1043,1005]	9	hSpCas9	negative selection	5044217
159917548	159917570	5	-	27760321	HT29	viability after 19 days	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	0.4927711802280873	[335,261]	[307,795,326]	5	hSpCas9	negative selection	5044218
159917671	159917693	5	+	27760321	HT29	viability after 19 days	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.5197495058129602	[264,206]	[466,178,517]	5	hSpCas9	negative selection	5044219
159917204	159917226	5	-	27760321	HT29	viability after 16 days	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	0.10275701708061782	[371,289]	[251,553,368]	1	hSpCas9	negative selection	5127678
159917310	159917332	5	-	27760321	HT29	viability after 16 days	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.6539282900763635	[491,383]	[884,532,911]	7	hSpCas9	negative selection	5127679
159917464	159917486	5	+	27760321	HT29	viability after 16 days	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.6446712612959028	[428,334]	[732,536,743]	7	hSpCas9	negative selection	5127680
159917548	159917570	5	-	27760321	HT29	viability after 16 days	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	-0.08032437415109495	[335,261]	[429,233,297]	-1	hSpCas9	negative selection	5127681
159917671	159917693	5	+	27760321	HT29	viability after 16 days	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.16644313085355283	[264,206]	[349,144,402]	1	hSpCas9	negative selection	5127682
159917204	159917226	5	-	27760321	HT29	viability after 13 days	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	0.11225569750655845	[371,289]	[376,450,416]	1	hSpCas9	negative selection	5211141
159917310	159917332	5	-	27760321	HT29	viability after 13 days	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.3938985382857175	[491,383]	[739,600,661]	5	hSpCas9	negative selection	5211142
159917464	159917486	5	+	27760321	HT29	viability after 13 days	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.6112924530245214	[428,334]	[546,871,615]	7	hSpCas9	negative selection	5211143
159917548	159917570	5	-	27760321	HT29	viability after 13 days	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	0.15318965040766597	[335,261]	[254,288,599]	1	hSpCas9	negative selection	5211144
159917671	159917693	5	+	27760321	HT29	viability after 13 days	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.7271592484527843	[264,206]	[562,472,330]	8	hSpCas9	negative selection	5211145
159917204	159917226	5	-	27760321	HT29	viability after 10 days	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	0.14157460556206608	[371,289]	[643,321,398]	1	hSpCas9	negative selection	5294604
159917310	159917332	5	-	27760321	HT29	viability after 10 days	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.23844186453125993	[491,383]	[687,578,665]	3	hSpCas9	negative selection	5294605
159917464	159917486	5	+	27760321	HT29	viability after 10 days	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.5212982780697542	[428,334]	[670,578,797]	7	hSpCas9	negative selection	5294606
159917548	159917570	5	-	27760321	HT29	viability after 10 days	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	0.42652764223624906	[335,261]	[471,473,556]	6	hSpCas9	negative selection	5294607
159917671	159917693	5	+	27760321	HT29	viability after 10 days	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.07622322653054625	[264,206]	[361,288,280]	1	hSpCas9	negative selection	5294608
159917204	159917226	5	-	27760321	MOLM13	viability	ACCTCTAGGGCCGCTGAGAAGG	ADRA1B	ENSG00000170214	-1.0984278858553669	[478,371]	[153,74]	-6	hSpCas9	negative selection	5378067
159917310	159917332	5	-	27760321	MOLM13	viability	ATCGATGGAGATGGCGCACAGG	ADRA1B	ENSG00000170214	0.1580037671330496	[575,491]	[454,232]	1	hSpCas9	negative selection	5378068
159917464	159917486	5	+	27760321	MOLM13	viability	CCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	1.1376759456139882	[534,428]	[501,673]	7	hSpCas9	negative selection	5378069
159917548	159917570	5	-	27760321	MOLM13	viability	TGACTAGAATGACCGCCAGAGG	ADRA1B	ENSG00000170214	0.5420541490485731	[395,335]	[196,386]	4	hSpCas9	negative selection	5378070
159917671	159917693	5	+	27760321	MOLM13	viability	CATTCCAAGAACTTTCACGAGG	ADRA1B	ENSG00000170214	0.6463579313627384	[317,264]	[244,265]	4	hSpCas9	negative selection	5378071
159916763	159916786	5	-	27661255	K562	viability	GGCGAGGAGTCATCTCCCCCGGG	ADRA1B	ENSG00000170214	0.2986492982407637	[332,417]	[462,285]	8	dCas9-KRAB	negative selection	5461182
159971998	159972021	5	+	27260156	BXPC3	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.47451361838352424	[873]	[1178,1135,1284,1518]	8	hSpCas9	negative selection	5527203
159972097	159972120	5	-	27260156	BXPC3	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.5447394180512012	[221]	[324,295,323,420]	9	hSpCas9	negative selection	5527204
159917571	159917594	5	+	27260156	BXPC3	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.06959048571185211	[249]	[191,211,284,323]	-2	hSpCas9	negative selection	5527205
159917833	159917856	5	+	27260156	BXPC3	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.1674791525961392	[1122]	[1324,1343,1318,1268]	3	hSpCas9	negative selection	5591485
159917471	159917494	5	-	27260156	BXPC3	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.20596669546250912	[840]	[940,961,1049,1121]	4	hSpCas9	negative selection	5591486
159917423	159917446	5	-	27260156	BXPC3	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.19007413167457377	[117]	[115,158,112,179]	4	hSpCas9	negative selection	5591487
159971998	159972021	5	+	27260156	A673	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.4339332208668413	[873]	[1458,1320,1282,1624]	8	hSpCas9	negative selection	5648454
159972097	159972120	5	-	27260156	A673	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.05139541482613885	[221]	[303,238,309,253]	1	hSpCas9	negative selection	5648455
159917571	159917594	5	+	27260156	A673	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.22759709787717053	[249]	[327,210,203,293]	-5	hSpCas9	negative selection	5648456
159917833	159917856	5	+	27260156	A673	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.31861413686934315	[1122]	[2030,1527,1498,1712]	7	hSpCas9	negative selection	5712736
159917471	159917494	5	-	27260156	A673	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.0270882795591304	[840]	[1182,949,929,1073]	0	hSpCas9	negative selection	5712737
159917423	159917446	5	-	27260156	A673	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.05004441324305464	[117]	[186,173,111,115]	1	hSpCas9	negative selection	5712738
159971998	159972021	5	+	27260156	A375	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.6644319959812764	[873]	[1483,1825,1884,1332]	8	hSpCas9	negative selection	5769705
159972097	159972120	5	-	27260156	A375	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.0030932569733881365	[221]	[244,235,275,275]	0	hSpCas9	negative selection	5769706
159917571	159917594	5	+	27260156	A375	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.5530447948778899	[249]	[121,184,260,221]	-6	hSpCas9	negative selection	5769707
159917833	159917856	5	+	27260156	A375	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.488655810172377	[1122]	[1706,2205,1896,1620]	7	hSpCas9	negative selection	5833987
159917471	159917494	5	-	27260156	A375	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-0.09110814690357516	[840]	[735,1192,1023,784]	-1	hSpCas9	negative selection	5833988
159917423	159917446	5	-	27260156	A375	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.1986472719425907	[117]	[147,114,204,157]	3	hSpCas9	negative selection	5833989
159971998	159972021	5	+	27260156	COLO741	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.6550167713132525	[873]	[2659,1402,1316]	9	hSpCas9	negative selection	5890956
159972097	159972120	5	-	27260156	COLO741	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.18544111066538604	[221]	[353,354,264]	4	hSpCas9	negative selection	5890957
159917571	159917594	5	+	27260156	COLO741	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.15890438615663605	[249]	[386,275,208]	-3	hSpCas9	negative selection	5890958
159917833	159917856	5	+	27260156	COLO741	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.1459956772000226	[1122]	[1615,1588,1558]	3	hSpCas9	negative selection	5955238
159917471	159917494	5	-	27260156	COLO741	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.07223453832928894	[840]	[1139,1124,1122]	1	hSpCas9	negative selection	5955239
159917423	159917446	5	-	27260156	COLO741	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.39105383468587873	[117]	[233,223,141]	7	hSpCas9	negative selection	5955240
159971998	159972021	5	+	27260156	CAL120	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.4766007839280032	[873]	[1846,1362,1381]	7	hSpCas9	negative selection	6012207
159972097	159972120	5	-	27260156	CAL120	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.7543711363993176	[221]	[878,227,354]	9	hSpCas9	negative selection	6012208
159917571	159917594	5	+	27260156	CAL120	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.37626203844810846	[249]	[320,104,303]	-5	hSpCas9	negative selection	6012209
159917833	159917856	5	+	27260156	CAL120	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.34604338000445156	[1122]	[1873,1595,1870]	5	hSpCas9	negative selection	6076489
159917471	159917494	5	-	27260156	CAL120	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.18519068363010216	[840]	[1433,1325,851]	2	hSpCas9	negative selection	6076490
159917423	159917446	5	-	27260156	CAL120	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.33967687717792705	[117]	[232,91,41]	-5	hSpCas9	negative selection	6076491
159971998	159972021	5	+	27260156	CADOES1	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.8637716436753894	[873]	[1259,2012,1312,1326]	9	hSpCas9	negative selection	6133458
159972097	159972120	5	-	27260156	CADOES1	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.47076124274058295	[221]	[314,239,261,328]	7	hSpCas9	negative selection	6133459
159917571	159917594	5	+	27260156	CADOES1	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.4707689831507812	[249]	[193,175,185,112]	-7	hSpCas9	negative selection	6133460
159917833	159917856	5	+	27260156	CADOES1	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.025726246077965254	[1122]	[960,1018,1212,1059]	0	hSpCas9	negative selection	6197740
159917471	159917494	5	-	27260156	CADOES1	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-0.020680033166290857	[840]	[843,761,604,876]	0	hSpCas9	negative selection	6197741
159917423	159917446	5	-	27260156	CADOES1	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.08508985307838657	[117]	[85,102,92,132]	-1	hSpCas9	negative selection	6197742
159971998	159972021	5	+	27260156	EWS502	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.7015432864153829	[873]	[1098,1376,1835,1782]	9	hSpCas9	negative selection	6254709
159972097	159972120	5	-	27260156	EWS502	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.290817657313987	[221]	[258,303,357,227]	5	hSpCas9	negative selection	6254710
159917571	159917594	5	+	27260156	EWS502	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.6513397009546148	[249]	[129,221,155,167]	-8	hSpCas9	negative selection	6254711
159917833	159917856	5	+	27260156	EWS502	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.28190511426991516	[1122]	[1532,1281,1338,1632]	5	hSpCas9	negative selection	6318991
159917471	159917494	5	-	27260156	EWS502	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.03715938541062236	[840]	[878,828,990,965]	0	hSpCas9	negative selection	6318992
159917423	159917446	5	-	27260156	EWS502	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.13256527466807766	[117]	[153,115,81,96]	-2	hSpCas9	negative selection	6318993
159971998	159972021	5	+	27260156	EW8	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.5442979086347729	[873]	[1269,954,947,995]	8	hSpCas9	negative selection	6375960
159972097	159972120	5	-	27260156	EW8	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.12986936473226707	[221]	[309,160,90,254]	2	hSpCas9	negative selection	6375961
159917571	159917594	5	+	27260156	EW8	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.2721949938714353	[249]	[206,192,102,182]	-5	hSpCas9	negative selection	6375962
159917833	159917856	5	+	27260156	EW8	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.35680279304807905	[1122]	[1087,1219,781,1623]	6	hSpCas9	negative selection	6440242
159917471	159917494	5	-	27260156	EW8	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.005433075914277552	[840]	[840,607,591,725]	0	hSpCas9	negative selection	6440243
159917423	159917446	5	-	27260156	EW8	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.2756355826516903	[117]	[131,68,58,64]	-5	hSpCas9	negative selection	6440244
159971998	159972021	5	+	27260156	CORL105	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.7410733954406853	[873]	[1661,1459,2109,1673]	9	hSpCas9	negative selection	6497211
159972097	159972120	5	-	27260156	CORL105	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.2636083586142831	[221]	[296,283,369,305]	5	hSpCas9	negative selection	6497212
159917571	159917594	5	+	27260156	CORL105	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.16356684470061766	[249]	[186,338,235,274]	-3	hSpCas9	negative selection	6497213
159917833	159917856	5	+	27260156	CORL105	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.1774596663787127	[1122]	[1596,1367,1701,1319]	3	hSpCas9	negative selection	6561493
159917471	159917494	5	-	27260156	CORL105	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.09639296810799947	[840]	[1243,810,1164,1018]	1	hSpCas9	negative selection	6561494
159917423	159917446	5	-	27260156	CORL105	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.23337632781633122	[117]	[89,81,151,150]	-4	hSpCas9	negative selection	6561495
159971998	159972021	5	+	27260156	HS294T	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.6370372259933829	[873]	[522,636,414,520]	8	hSpCas9	negative selection	6618462
159972097	159972120	5	-	27260156	HS294T	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.9744810603329236	[221]	[97,188,245,142]	9	hSpCas9	negative selection	6618463
159917571	159917594	5	+	27260156	HS294T	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.6927791378057747	[249]	[60,42,67,68]	-7	hSpCas9	negative selection	6618464
159917833	159917856	5	+	27260156	HS294T	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	-0.18029995958227873	[1122]	[544,286,333,346]	-3	hSpCas9	negative selection	6682744
159917471	159917494	5	-	27260156	HS294T	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.3628741052689267	[840]	[495,315,412,446]	5	hSpCas9	negative selection	6682745
159917423	159917446	5	-	27260156	HS294T	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.017060789150989297	[117]	[19,48,70,41]	0	hSpCas9	negative selection	6682746
159971998	159972021	5	+	27260156	HCC44	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.4409709054930365	[873]	[1236,1042,1899,1306]	7	hSpCas9	negative selection	6739713
159972097	159972120	5	-	27260156	HCC44	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.3177376112014476	[221]	[261,309,345,331]	5	hSpCas9	negative selection	6739714
159917571	159917594	5	+	27260156	HCC44	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.6109341290164488	[249]	[90,123,374,181]	-7	hSpCas9	negative selection	6739715
159917833	159917856	5	+	27260156	HCC44	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.14810996651907304	[1122]	[1551,1175,1841,1176]	2	hSpCas9	negative selection	6803995
159917471	159917494	5	-	27260156	HCC44	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.1514803954382714	[840]	[1217,878,1047,1108]	2	hSpCas9	negative selection	6803996
159917423	159917446	5	-	27260156	HCC44	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.2948378248253274	[117]	[116,77,70,164]	-5	hSpCas9	negative selection	6803997
159971998	159972021	5	+	27260156	G402	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.9018110278595538	[873]	[1924,2307,2208,1550]	9	hSpCas9	negative selection	6860964
159972097	159972120	5	-	27260156	G402	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	-0.01850002188718447	[221]	[418,237,145,284]	0	hSpCas9	negative selection	6860965
159917571	159917594	5	+	27260156	G402	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.7670391892448113	[249]	[297,202,78,155]	-7	hSpCas9	negative selection	6860966
159917833	159917856	5	+	27260156	G402	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.40325148177903447	[1122]	[1700,1792,2076,1660]	5	hSpCas9	negative selection	6925246
159917471	159917494	5	-	27260156	G402	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-0.07054895022391783	[840]	[919,1291,511,1180]	-1	hSpCas9	negative selection	6925247
159917423	159917446	5	-	27260156	G402	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.3737766695804816	[117]	[176,187,229,150]	5	hSpCas9	negative selection	6925248
159971998	159972021	5	+	27260156	L33	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.20735756533893934	[873]	[960,382,784,894]	4	hSpCas9	negative selection	6982215
159972097	159972120	5	-	27260156	L33	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.25173229034809597	[221]	[298,112,135,264]	5	hSpCas9	negative selection	6982216
159917571	159917594	5	+	27260156	L33	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.3431121914039156	[249]	[223,74,115,195]	-7	hSpCas9	negative selection	6982217
159917833	159917856	5	+	27260156	L33	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	-0.06667706032804754	[1122]	[1150,436,664,1011]	-1	hSpCas9	negative selection	7046497
159917471	159917494	5	-	27260156	L33	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.1977765658599352	[840]	[1030,402,585,909]	4	hSpCas9	negative selection	7046498
159917423	159917446	5	-	27260156	L33	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.11615981652708385	[117]	[116,41,61,116]	-3	hSpCas9	negative selection	7046499
159971998	159972021	5	+	27260156	K562	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	1.0264849711370956	[873]	[1836,1511,1782,1238]	9	hSpCas9	negative selection	7103466
159972097	159972120	5	-	27260156	K562	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.15434970500271372	[221]	[236,192,215,228]	2	hSpCas9	negative selection	7103467
159917571	159917594	5	+	27260156	K562	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.4913447770400753	[249]	[204,67,238,121]	-5	hSpCas9	negative selection	7103468
159917833	159917856	5	+	27260156	K562	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.5971701073530244	[1122]	[1512,1388,1041,2013]	7	hSpCas9	negative selection	7167748
159917471	159917494	5	-	27260156	K562	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.6248557636129665	[840]	[1134,1207,1065,1186]	7	hSpCas9	negative selection	7167749
159917423	159917446	5	-	27260156	K562	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	1.174824145937912	[117]	[158,247,201,319]	9	hSpCas9	negative selection	7167750
159971998	159972021	5	+	27260156	HT29	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.573332957472125	[873]	[1746,1634,1497,1463]	9	hSpCas9	negative selection	7224717
159972097	159972120	5	-	27260156	HT29	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.03693745336187848	[221]	[267,366,276,208]	0	hSpCas9	negative selection	7224718
159917571	159917594	5	+	27260156	HT29	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.42317627710387107	[249]	[259,220,297,138]	-7	hSpCas9	negative selection	7224719
159917833	159917856	5	+	27260156	HT29	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.36053406571750224	[1122]	[2010,1654,1846,1524]	7	hSpCas9	negative selection	7288999
159917471	159917494	5	-	27260156	HT29	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.19454804284000093	[840]	[1268,1268,1048,1107]	4	hSpCas9	negative selection	7289000
159917423	159917446	5	-	27260156	HT29	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.24817852999964418	[117]	[200,236,166,92]	5	hSpCas9	negative selection	7289001
159971998	159972021	5	+	27260156	MHHES1	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.7290222118218869	[873]	[2089,1665,1520,1338]	9	hSpCas9	negative selection	7345968
159972097	159972120	5	-	27260156	MHHES1	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	-0.202497889232635	[221]	[170,160,271,242]	-4	hSpCas9	negative selection	7345969
159917571	159917594	5	+	27260156	MHHES1	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.31674612926741597	[249]	[254,206,194,239]	-5	hSpCas9	negative selection	7345970
159917833	159917856	5	+	27260156	MHHES1	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.09090835992752444	[1122]	[1723,1343,1092,1259]	1	hSpCas9	negative selection	7410250
159917471	159917494	5	-	27260156	MHHES1	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.09901451200076838	[840]	[1168,1051,1075,808]	1	hSpCas9	negative selection	7410251
159917423	159917446	5	-	27260156	MHHES1	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.2521352164340387	[117]	[157,230,127,126]	4	hSpCas9	negative selection	7410252
159971998	159972021	5	+	27260156	MEWO	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.2299743135284208	[873]	[1142,835,933]	5	hSpCas9	negative selection	7467219
159972097	159972120	5	-	27260156	MEWO	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.13940194929330385	[221]	[225,168,290]	3	hSpCas9	negative selection	7467220
159917571	159917594	5	+	27260156	MEWO	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.3065357099315982	[249]	[439,272,183]	6	hSpCas9	negative selection	7467221
159917833	159917856	5	+	27260156	MEWO	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.3368189505134944	[1122]	[1416,1309,1270]	7	hSpCas9	negative selection	7531501
159917471	159917494	5	-	27260156	MEWO	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.27654962959660223	[840]	[1123,967,799]	6	hSpCas9	negative selection	7531502
159917423	159917446	5	-	27260156	MEWO	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.06357845416634467	[117]	[80,128,101]	-1	hSpCas9	negative selection	7531503
159971998	159972021	5	+	27260156	LNCAPCLONEFGC	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.736784185171803	[873]	[1151,1294,1666,1218]	9	hSpCas9	negative selection	7588470
159972097	159972120	5	-	27260156	LNCAPCLONEFGC	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.6005149901610449	[221]	[198,284,433,323]	8	hSpCas9	negative selection	7588471
159917571	159917594	5	+	27260156	LNCAPCLONEFGC	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.3803282878358615	[249]	[183,135,226,158]	-5	hSpCas9	negative selection	7588472
159917833	159917856	5	+	27260156	LNCAPCLONEFGC	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.252688911718004	[1122]	[1043,1130,1630,1111]	4	hSpCas9	negative selection	7652752
159917471	159917494	5	-	27260156	LNCAPCLONEFGC	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.20833017583222502	[840]	[881,692,1011,964]	3	hSpCas9	negative selection	7652753
159917423	159917446	5	-	27260156	LNCAPCLONEFGC	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.008801552103754329	[117]	[85,89,150,105]	0	hSpCas9	negative selection	7652754
159971998	159972021	5	+	27260156	PANC0327	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.5946183448509498	[873]	[1483,976,1157,1120]	8	hSpCas9	negative selection	7709721
159972097	159972120	5	-	27260156	PANC0327	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.20941814256487834	[221]	[282,183,155,298]	3	hSpCas9	negative selection	7709722
159917571	159917594	5	+	27260156	PANC0327	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.1393817703243595	[249]	[331,115,217,335]	2	hSpCas9	negative selection	7709723
159917833	159917856	5	+	27260156	PANC0327	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.11216253990476477	[1122]	[1403,1095,998,837]	1	hSpCas9	negative selection	7774003
159917471	159917494	5	-	27260156	PANC0327	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.33478945213030287	[840]	[770,1303,974,657]	5	hSpCas9	negative selection	7774004
159917423	159917446	5	-	27260156	PANC0327	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.7942496348827164	[117]	[224,76,151,289]	9	hSpCas9	negative selection	7774005
159971998	159972021	5	+	27260156	NCIH2009	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.6645290759105124	[873]	[2136,1721,1987]	8	hSpCas9	negative selection	7830972
159972097	159972120	5	-	27260156	NCIH2009	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.6598177264851697	[221]	[433,389,635]	8	hSpCas9	negative selection	7830973
159917571	159917594	5	+	27260156	NCIH2009	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.012307792997604206	[249]	[411,299,356]	0	hSpCas9	negative selection	7830974
159917833	159917856	5	+	27260156	NCIH2009	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.30139907890924733	[1122]	[1913,1960,1917]	4	hSpCas9	negative selection	7895254
159917471	159917494	5	-	27260156	NCIH2009	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.22881855150332664	[840]	[1685,1411,1090]	3	hSpCas9	negative selection	7895255
159917423	159917446	5	-	27260156	NCIH2009	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.22628636222115617	[117]	[120,305,134]	3	hSpCas9	negative selection	7895256
159971998	159972021	5	+	27260156	NCIH1373	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	1.3027508463405395	[873]	[3610,2342,2067,471]	9	hSpCas9	negative selection	7952223
159972097	159972120	5	-	27260156	NCIH1373	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.7990922207247989	[221]	[835,349,375,59]	7	hSpCas9	negative selection	7952224
159917571	159917594	5	+	27260156	NCIH1373	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.372097536460844	[249]	[227,204,224,54]	-4	hSpCas9	negative selection	7952225
159917833	159917856	5	+	27260156	NCIH1373	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	-0.24207300175771196	[1122]	[891,1233,1291,200]	-2	hSpCas9	negative selection	8016505
159917471	159917494	5	-	27260156	NCIH1373	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.297809908621966	[840]	[2105,1268,615,199]	3	hSpCas9	negative selection	8016506
159917423	159917446	5	-	27260156	NCIH1373	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.03836058707779566	[117]	[201,45,198,21]	0	hSpCas9	negative selection	8016507
159971998	159972021	5	+	27260156	PATU8902	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	1.0175869926499406	[873]	[2818,2185,2201,2723]	9	hSpCas9	negative selection	8073474
159972097	159972120	5	-	27260156	PATU8902	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.39364678678138343	[221]	[343,383,487,381]	4	hSpCas9	negative selection	8073475
159917571	159917594	5	+	27260156	PATU8902	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.46902793315621916	[249]	[136,417,165,314]	-4	hSpCas9	negative selection	8073476
159917833	159917856	5	+	27260156	PATU8902	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	-0.24288648968256044	[1122]	[1348,1166,794,2206]	-2	hSpCas9	negative selection	8137756
159917471	159917494	5	-	27260156	PATU8902	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-1.1032596716185976	[840]	[259,1185,289,507]	-7	hSpCas9	negative selection	8137757
159917423	159917446	5	-	27260156	PATU8902	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.17196766490836413	[117]	[25,441,10,324]	1	hSpCas9	negative selection	8137758
159971998	159972021	5	+	27260156	PANC1	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.5017830126070825	[873]	[1131,1393,976,834]	7	hSpCas9	negative selection	8194725
159972097	159972120	5	-	27260156	PANC1	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.43347109917646454	[221]	[198,407,249,208]	7	hSpCas9	negative selection	8194726
159917571	159917594	5	+	27260156	PANC1	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.10495682967228526	[249]	[237,222,311,157]	1	hSpCas9	negative selection	8194727
159917833	159917856	5	+	27260156	PANC1	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.2696030769588287	[1122]	[902,1642,1186,1025]	4	hSpCas9	negative selection	8259007
159917471	159917494	5	-	27260156	PANC1	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-0.11796100354566619	[840]	[663,778,645,596]	-2	hSpCas9	negative selection	8259008
159917423	159917446	5	-	27260156	PANC1	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.40511897249739537	[117]	[67,97,103,44]	-6	hSpCas9	negative selection	8259009
159971998	159972021	5	+	27260156	PANC0813	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.6871094848992579	[873]	[2260,1352,1805,1267]	9	hSpCas9	negative selection	8315976
159972097	159972120	5	-	27260156	PANC0813	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.4388883155840412	[221]	[319,376,371,341]	7	hSpCas9	negative selection	8315977
159917571	159917594	5	+	27260156	PANC0813	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.042439528241499214	[249]	[497,230,313,125]	0	hSpCas9	negative selection	8315978
159917833	159917856	5	+	27260156	PANC0813	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.2237621339133551	[1122]	[1761,1505,1509,1408]	3	hSpCas9	negative selection	8380258
159917471	159917494	5	-	27260156	PANC0813	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.2653517343467712	[840]	[1400,958,1348,1065]	4	hSpCas9	negative selection	8380259
159917423	159917446	5	-	27260156	PANC0813	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.3333751059829648	[117]	[125,235,265,71]	5	hSpCas9	negative selection	8380260
159971998	159972021	5	+	27260156	RDES	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.8087016630671918	[873]	[1269,1853,1938,2080]	9	hSpCas9	negative selection	8437227
159972097	159972120	5	-	27260156	RDES	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.5938216619702548	[221]	[292,479,394,369]	8	hSpCas9	negative selection	8437228
159917571	159917594	5	+	27260156	RDES	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.3965110208853734	[249]	[170,218,235,257]	-6	hSpCas9	negative selection	8437229
159917833	159917856	5	+	27260156	RDES	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.28678733082495844	[1122]	[1293,1427,1742,1923]	4	hSpCas9	negative selection	8501509
159917471	159917494	5	-	27260156	RDES	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-0.027546086738029496	[840]	[868,929,962,1034]	0	hSpCas9	negative selection	8501510
159917423	159917446	5	-	27260156	RDES	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.3895855796030605	[117]	[112,242,147,213]	6	hSpCas9	negative selection	8501511
159971998	159972021	5	+	27260156	PC3	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.5660743070097648	[873]	[722,1231,2492,1319]	9	hSpCas9	negative selection	8558478
159972097	159972120	5	-	27260156	PC3	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.0276830370574237	[221]	[155,204,400,215]	0	hSpCas9	negative selection	8558479
159917571	159917594	5	+	27260156	PC3	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.09267231491103856	[249]	[122,234,528,325]	2	hSpCas9	negative selection	8558480
159917833	159917856	5	+	27260156	PC3	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.24824995950513506	[1122]	[701,1322,2643,1325]	5	hSpCas9	negative selection	8622760
159917471	159917494	5	-	27260156	PC3	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.013602981538772041	[840]	[461,795,1668,878]	0	hSpCas9	negative selection	8622761
159917423	159917446	5	-	27260156	PC3	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.301926306805711	[117]	[39,65,254,102]	-6	hSpCas9	negative selection	8622762
159971998	159972021	5	+	27260156	PATU8988T	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.23165805144524343	[873]	[1110,883,995,962]	4	hSpCas9	negative selection	8679729
159972097	159972120	5	-	27260156	PATU8988T	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.10949438922047439	[221]	[148,131,303,338]	2	hSpCas9	negative selection	8679730
159917571	159917594	5	+	27260156	PATU8988T	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.39692889673932863	[249]	[162,115,179,275]	-6	hSpCas9	negative selection	8679731
159917833	159917856	5	+	27260156	PATU8988T	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.17461846017686966	[1122]	[1315,1543,1112,933]	3	hSpCas9	negative selection	8744011
159917471	159917494	5	-	27260156	PATU8988T	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-0.10427856783510858	[840]	[510,861,889,769]	-2	hSpCas9	negative selection	8744012
159917423	159917446	5	-	27260156	PATU8988T	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.32865902565545935	[117]	[132,165,54,228]	5	hSpCas9	negative selection	8744013
159971998	159972021	5	+	27260156	T47D	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.4120813540900531	[873]	[1516,1213,1201,1505]	8	hSpCas9	negative selection	8800980
159972097	159972120	5	-	27260156	T47D	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.2530029191517291	[221]	[358,209,395,273]	5	hSpCas9	negative selection	8800981
159917571	159917594	5	+	27260156	T47D	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.40706326586736463	[249]	[219,186,229,244]	-7	hSpCas9	negative selection	8800982
159917833	159917856	5	+	27260156	T47D	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.1179129363246616	[1122]	[1606,1544,1165,1351]	2	hSpCas9	negative selection	8865262
159917471	159917494	5	-	27260156	T47D	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.069569816267255	[840]	[1105,959,995,1057]	1	hSpCas9	negative selection	8865263
159917423	159917446	5	-	27260156	T47D	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.2386249204996176	[117]	[114,84,114,154]	-5	hSpCas9	negative selection	8865264
159971998	159972021	5	+	27260156	SU8686	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.6835707040390192	[873]	[1196,1217,1587,1644]	9	hSpCas9	negative selection	8922231
159972097	159972120	5	-	27260156	SU8686	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.42165893599118387	[221]	[240,217,333,421]	7	hSpCas9	negative selection	8922232
159917571	159917594	5	+	27260156	SU8686	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	0.01574359663779723	[249]	[272,282,214,215]	0	hSpCas9	negative selection	8922233
159917833	159917856	5	+	27260156	SU8686	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.06370707540375964	[1122]	[1208,960,1368,1127]	1	hSpCas9	negative selection	8986513
159917471	159917494	5	-	27260156	SU8686	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.09927453134800535	[840]	[837,874,1000,857]	1	hSpCas9	negative selection	8986514
159917423	159917446	5	-	27260156	SU8686	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.009862062367249624	[117]	[75,133,89,174]	0	hSpCas9	negative selection	8986515
159971998	159972021	5	+	27260156	SKES1	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.5372663137710124	[873]	[1487,1743,903,1032]	9	hSpCas9	negative selection	9043482
159972097	159972120	5	-	27260156	SKES1	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.34502666186476283	[221]	[255,343,248,277]	7	hSpCas9	negative selection	9043483
159917571	159917594	5	+	27260156	SKES1	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.02169383878704989	[249]	[192,389,201,209]	0	hSpCas9	negative selection	9043484
159917833	159917856	5	+	27260156	SKES1	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.16758299640875784	[1122]	[1596,1167,1278,1037]	3	hSpCas9	negative selection	9107764
159917471	159917494	5	-	27260156	SKES1	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.10042239407304743	[840]	[1204,875,775,785]	2	hSpCas9	negative selection	9107765
159917423	159917446	5	-	27260156	SKES1	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.09450188845240426	[117]	[113,110,170,103]	2	hSpCas9	negative selection	9107766
159971998	159972021	5	+	27260156	TOV112D	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.568014584745948	[873]	[1575,1599,831,1278]	8	hSpCas9	negative selection	9164733
159972097	159972120	5	-	27260156	TOV112D	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.047126260213893545	[221]	[192,421,126,220]	0	hSpCas9	negative selection	9164734
159917571	159917594	5	+	27260156	TOV112D	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.17381431836832528	[249]	[335,240,182,143]	-3	hSpCas9	negative selection	9164735
159917833	159917856	5	+	27260156	TOV112D	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.18908374660378113	[1122]	[1512,1446,1203,1029]	3	hSpCas9	negative selection	9229015
159917471	159917494	5	-	27260156	TOV112D	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	-0.02651163424711911	[840]	[663,1188,887,645]	0	hSpCas9	negative selection	9229016
159917423	159917446	5	-	27260156	TOV112D	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.5878903242352638	[117]	[236,235,201,57]	9	hSpCas9	negative selection	9229017
159971998	159972021	5	+	27260156	TC71	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.46897483037528664	[873]	[1283,1144,1395,1362]	9	hSpCas9	negative selection	9285984
159972097	159972120	5	-	27260156	TC71	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	0.25931425735184976	[221]	[299,247,337,248]	6	hSpCas9	negative selection	9285985
159917571	159917594	5	+	27260156	TC71	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.1830350805195592	[249]	[194,182,318,245]	-5	hSpCas9	negative selection	9285986
159917833	159917856	5	+	27260156	TC71	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.13140281876263482	[1122]	[1344,1435,1130,1370]	3	hSpCas9	negative selection	9350266
159917471	159917494	5	-	27260156	TC71	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.04113024221474326	[840]	[860,949,993,902]	1	hSpCas9	negative selection	9350267
159917423	159917446	5	-	27260156	TC71	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.14007814451593492	[117]	[131,117,194,108]	3	hSpCas9	negative selection	9350268
159971998	159972021	5	+	27260156	TC32	viability	CGCGCTTTCGTGCGCATCCTCGG	ADRA1B	ENSG00000170214	0.6370117640723324	[873]	[1321,889,1455,1551]	9	hSpCas9	negative selection	9407235
159972097	159972120	5	-	27260156	TC32	viability	AGCGAGCCGCCGCGCGTCCACGG	ADRA1B	ENSG00000170214	-0.1433383010970899	[221]	[114,217,249,167]	-3	hSpCas9	negative selection	9407236
159917571	159917594	5	+	27260156	TC32	viability	GTACTGCCGTGTCTATATAGTGG	ADRA1B	ENSG00000170214	-0.12461092635419246	[249]	[198,151,286,251]	-2	hSpCas9	negative selection	9407237
159917833	159917856	5	+	27260156	TC32	viability	TTCTTCATCGCTCTACCGCTTGG	ADRA1B	ENSG00000170214	0.16621206822820223	[1122]	[1204,965,1387,1220]	3	hSpCas9	negative selection	9471517
159917471	159917494	5	-	27260156	TC32	viability	CCCGCACTCCTTGTCATCGTTGG	ADRA1B	ENSG00000170214	0.10930217501864514	[840]	[923,593,1191,792]	2	hSpCas9	negative selection	9471518
159917423	159917446	5	-	27260156	TC32	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.07788249924971002	[117]	[92,75,213,113]	1	hSpCas9	negative selection	9471519
159917178	159917201	5	-	27869803	HPAFII	viability after 27 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-0.24780145288748395	[300]	[147,120,NaN]	-2	hSpCas9	negative selection	9590939
159917363	159917386	5	+	27869803	HPAFII	viability after 27 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.4544328575895788	[194]	[100,52,NaN]	-3	hSpCas9	negative selection	9590940
159917390	159917413	5	-	27869803	HPAFII	viability after 27 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	-0.6150450997879924	[231]	[83,75,NaN]	-4	hSpCas9	negative selection	9590941
159917463	159917486	5	+	27869803	HPAFII	viability after 27 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.028787134702073724	[318]	[133,201,NaN]	0	hSpCas9	negative selection	9590942
159971902	159971925	5	-	27869803	HPAFII	viability after 27 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-0.8128996239667393	[136]	[82,5,NaN]	-5	hSpCas9	negative selection	9590945
159972241	159972264	5	-	27869803	HPAFII	viability after 27 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	-0.19022115493168312	[159]	[28,110,NaN]	-1	hSpCas9	negative selection	9590946
159917178	159917201	5	-	27869803	HPAFII	viability after 15 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.12678221189254302	[300]	[441,297,NaN]	1	hSpCas9	negative selection	9673388
159917363	159917386	5	+	27869803	HPAFII	viability after 15 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.9101761120012091	[194]	[121,104,NaN]	-7	hSpCas9	negative selection	9673389
159917390	159917413	5	-	27869803	HPAFII	viability after 15 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.11350024732512415	[231]	[397,189,NaN]	1	hSpCas9	negative selection	9673390
159917463	159917486	5	+	27869803	HPAFII	viability after 15 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.3046627275948228	[318]	[428,419,NaN]	3	hSpCas9	negative selection	9673391
159971902	159971925	5	-	27869803	HPAFII	viability after 15 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-1.2739039365382263	[136]	[116,25,NaN]	-8	hSpCas9	negative selection	9673394
159972241	159972264	5	-	27869803	HPAFII	viability after 15 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	-0.1524609554997831	[159]	[105,184,NaN]	-2	hSpCas9	negative selection	9673395
159917178	159917201	5	-	27869803	ASPC1	viability after 36 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-0.34431770402323314	[632]	[183,128,200]	-4	hSpCas9	negative selection	9755837
159917363	159917386	5	+	27869803	ASPC1	viability after 36 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-1.4066533611782954	[477]	[109,61,29]	-8	hSpCas9	negative selection	9755838
159917390	159917413	5	-	27869803	ASPC1	viability after 36 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	0.6618383510409916	[399]	[138,94,375]	6	hSpCas9	negative selection	9755839
159917463	159917486	5	+	27869803	ASPC1	viability after 36 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	-0.12890376495353176	[793]	[355,275,160]	-1	hSpCas9	negative selection	9755840
159971902	159971925	5	-	27869803	ASPC1	viability after 36 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	0.14902287646861434	[187]	[27,3,157]	1	hSpCas9	negative selection	9755843
159972241	159972264	5	-	27869803	ASPC1	viability after 36 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	1.2427847120593185	[210]	[132,92,265]	9	hSpCas9	negative selection	9755844
159917178	159917201	5	-	27869803	PATU8988S	viability after 35 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.43069377284927357	[611]	[213,450,NaN]	5	hSpCas9	negative selection	9838286
159917363	159917386	5	+	27869803	PATU8988S	viability after 35 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.24857096325587152	[499]	[170,167,NaN]	-3	hSpCas9	negative selection	9838287
159917390	159917413	5	-	27869803	PATU8988S	viability after 35 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	-0.9244546153058106	[524]	[69,152,NaN]	-7	hSpCas9	negative selection	9838288
159917463	159917486	5	+	27869803	PATU8988S	viability after 35 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.9634334916200431	[564]	[319,567,NaN]	8	hSpCas9	negative selection	9838289
159971902	159971925	5	-	27869803	PATU8988S	viability after 35 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	0.15077331612382427	[283]	[118,134,NaN]	1	hSpCas9	negative selection	9838292
159972241	159972264	5	-	27869803	PATU8988S	viability after 35 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	0.660270213991461	[212]	[167,102,NaN]	7	hSpCas9	negative selection	9838293
159917178	159917201	5	-	27869803	PATU8988S	viability after 31 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.582363825618538	[611]	[305,440,NaN]	7	hSpCas9	negative selection	9920735
159917363	159917386	5	+	27869803	PATU8988S	viability after 31 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	0.33315154508085415	[499]	[255,244,NaN]	4	hSpCas9	negative selection	9920736
159917390	159917413	5	-	27869803	PATU8988S	viability after 31 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	-0.6536125088110366	[524]	[107,164,NaN]	-6	hSpCas9	negative selection	9920737
159917463	159917486	5	+	27869803	PATU8988S	viability after 31 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.9207428893867995	[564]	[301,584,NaN]	8	hSpCas9	negative selection	9920738
159971902	159971925	5	-	27869803	PATU8988S	viability after 31 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-0.2282656558521643	[283]	[53,150,NaN]	-3	hSpCas9	negative selection	9920741
159972241	159972264	5	-	27869803	PATU8988S	viability after 31 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	-0.00039180511957792596	[212]	[32,150,NaN]	0	hSpCas9	negative selection	9920742
159917178	159917201	5	-	27869803	HPAFII	viability after 35 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	0.3991233339914425	[300]	[88,326,NaN]	2	hSpCas9	negative selection	10003184
159917363	159917386	5	+	27869803	HPAFII	viability after 35 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.31994599326627565	[194]	[127,23,NaN]	-2	hSpCas9	negative selection	10003185
159917390	159917413	5	-	27869803	HPAFII	viability after 35 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	-0.05647062773488393	[231]	[111,113,NaN]	0	hSpCas9	negative selection	10003186
159917463	159917486	5	+	27869803	HPAFII	viability after 35 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	0.036895792653516446	[318]	[104,233,NaN]	0	hSpCas9	negative selection	10003187
159971902	159971925	5	-	27869803	HPAFII	viability after 35 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-0.266145962784922	[136]	[107,0,NaN]	-2	hSpCas9	negative selection	10003190
159972241	159972264	5	-	27869803	HPAFII	viability after 35 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	-1.2455166707039709	[159]	[4,66,NaN]	-6	hSpCas9	negative selection	10003191
159917178	159917201	5	-	27869803	HPAFII	viability after 31 days	GGACGGTGAAGCTCAACAGCAGG	ADRA1B	ENSG00000170214	-0.16758772029416905	[300]	[136,164,NaN]	-1	hSpCas9	negative selection	10085633
159917363	159917386	5	+	27869803	HPAFII	viability after 31 days	ATCCCACGCTGGTCACCCGGAGG	ADRA1B	ENSG00000170214	-0.8775834580758202	[194]	[60,57,NaN]	-5	hSpCas9	negative selection	10085634
159917390	159917413	5	-	27869803	HPAFII	viability after 31 days	GACACTGAGCAGCGCCAAGATGG	ADRA1B	ENSG00000170214	-0.26638658072558963	[231]	[124,89,NaN]	-2	hSpCas9	negative selection	10085635
159917463	159917486	5	+	27869803	HPAFII	viability after 31 days	GCCGGCACCCAACGATGACAAGG	ADRA1B	ENSG00000170214	-0.04204581251998207	[318]	[148,200,NaN]	0	hSpCas9	negative selection	10085636
159971902	159971925	5	-	27869803	HPAFII	viability after 31 days	ACCTTGAACACGGCGTCGGGGGG	ADRA1B	ENSG00000170214	-0.21699163189395454	[136]	[102,25,NaN]	-1	hSpCas9	negative selection	10085639
159972241	159972264	5	-	27869803	HPAFII	viability after 31 days	GGGAAGGCGCACAGCTCGACTGG	ADRA1B	ENSG00000170214	-1.1674018797614185	[159]	[5,76,NaN]	-6	hSpCas9	negative selection	10085640
159917318	159917341	5	-	28162770	P31FUJ	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	-0.08374639501966552	[293]	[325]	-1	hSpCas9	negative selection	10107684
159917199	159917222	5	-	28162770	P31FUJ	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	0.13116111027019595	[114]	[147]	1	hSpCas9	negative selection	10107685
159917423	159917446	5	-	28162770	P31FUJ	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.7821481370515927	[191]	[387]	8	hSpCas9	negative selection	10107686
159917443	159917466	5	-	28162770	P31FUJ	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.7111637606712934	[209]	[403]	7	hSpCas9	negative selection	10107687
159917598	159917621	5	+	28162770	P31FUJ	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.9731724574881069	[100]	[232]	9	hSpCas9	negative selection	10107688
159916997	159917020	5	-	28162770	P31FUJ	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	0.7421068146227909	[57]	[113]	8	hSpCas9	negative selection	10107689
159917016	159917039	5	+	28162770	P31FUJ	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.5696502189222213	[378]	[660]	6	hSpCas9	negative selection	10107690
159917516	159917539	5	-	28162770	P31FUJ	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-3.72634167737194	[213]	[18]	-9	hSpCas9	negative selection	10107691
159917066	159917089	5	-	28162770	P31FUJ	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	1.0127505018413034	[255]	[606]	9	hSpCas9	negative selection	10107692
159917174	159917197	5	-	28162770	P31FUJ	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	0.3708968588883632	[101]	[154]	4	hSpCas9	negative selection	10107693
159917318	159917341	5	-	28162770	TF1	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[417]	1	hSpCas9	negative selection	10277050
159917199	159917222	5	-	28162770	TF1	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[108]	1	hSpCas9	negative selection	10277051
159917423	159917446	5	-	28162770	TF1	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10277052
159917443	159917466	5	-	28162770	TF1	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[241]	1	hSpCas9	negative selection	10277053
159917598	159917621	5	+	28162770	TF1	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10277054
159916997	159917020	5	-	28162770	TF1	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10277055
159917016	159917039	5	+	28162770	TF1	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[351]	1	hSpCas9	negative selection	10277056
159917516	159917539	5	-	28162770	TF1	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10277057
159917066	159917089	5	-	28162770	TF1	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[485]	1	hSpCas9	negative selection	10277058
159917174	159917197	5	-	28162770	TF1	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10277059
159917318	159917341	5	-	28162770	SKM1	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.8065877350994086	[75]	[234]	7	hSpCas9	negative selection	10446416
159917199	159917222	5	-	28162770	SKM1	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	0.4003907233144426	[20]	[48]	4	hSpCas9	negative selection	10446417
159917423	159917446	5	-	28162770	SKM1	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	1.007268000464039	[55]	[198]	8	hSpCas9	negative selection	10446418
159917443	159917466	5	-	28162770	SKM1	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	1.2430933301998794	[64]	[271]	9	hSpCas9	negative selection	10446419
159917598	159917621	5	+	28162770	SKM1	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	-0.014646775964401393	[39]	[69]	0	hSpCas9	negative selection	10446420
159916997	159917020	5	-	28162770	SKM1	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-0.5740741845784201	[15]	[18]	-4	hSpCas9	negative selection	10446421
159917016	159917039	5	+	28162770	SKM1	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.29347551939793043	[65]	[142]	3	hSpCas9	negative selection	10446422
159917516	159917539	5	-	28162770	SKM1	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-0.7996338849935509	[63]	[64]	-5	hSpCas9	negative selection	10446423
159917066	159917089	5	-	28162770	SKM1	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	1.056157179043197	[70]	[260]	8	hSpCas9	negative selection	10446424
159917174	159917197	5	-	28162770	SKM1	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	-1.4069641987431618	[26]	[17]	-7	hSpCas9	negative selection	10446425
159917318	159917341	5	-	28162770	SKM1	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.8065877350994086	[75]	[234]	7	hSpCas9	negative selection	10615782
159917199	159917222	5	-	28162770	SKM1	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	0.4003907233144426	[20]	[48]	4	hSpCas9	negative selection	10615783
159917423	159917446	5	-	28162770	SKM1	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	1.007268000464039	[55]	[198]	8	hSpCas9	negative selection	10615784
159917443	159917466	5	-	28162770	SKM1	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	1.2430933301998794	[64]	[271]	9	hSpCas9	negative selection	10615785
159917598	159917621	5	+	28162770	SKM1	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	-0.014646775964401393	[39]	[69]	0	hSpCas9	negative selection	10615786
159916997	159917020	5	-	28162770	SKM1	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-0.5740741845784201	[15]	[18]	-4	hSpCas9	negative selection	10615787
159917016	159917039	5	+	28162770	SKM1	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.29347551939793043	[65]	[142]	3	hSpCas9	negative selection	10615788
159917516	159917539	5	-	28162770	SKM1	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-0.7996338849935509	[63]	[64]	-5	hSpCas9	negative selection	10615789
159917066	159917089	5	-	28162770	SKM1	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	1.056157179043197	[70]	[260]	8	hSpCas9	negative selection	10615790
159917174	159917197	5	-	28162770	SKM1	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	-1.4069641987431618	[26]	[17]	-7	hSpCas9	negative selection	10615791
159917318	159917341	5	-	28162770	PL21	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	-0.2672995827493432	[270]	[97]	-2	hSpCas9	negative selection	10785148
159917199	159917222	5	-	28162770	PL21	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	0.7948831360030615	[48]	[36]	6	hSpCas9	negative selection	10785149
159917423	159917446	5	-	28162770	PL21	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-1.0359277437442043	[211]	[44]	-6	hSpCas9	negative selection	10785150
159917443	159917466	5	-	28162770	PL21	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.9618518709912119	[288]	[244]	7	hSpCas9	negative selection	10785151
159917598	159917621	5	+	28162770	PL21	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.8355671821934639	[102]	[79]	7	hSpCas9	negative selection	10785152
159916997	159917020	5	-	28162770	PL21	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-2.5003001036517727	[51]	[3]	-9	hSpCas9	negative selection	10785153
159917016	159917039	5	+	28162770	PL21	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	-0.3491989765011147	[239]	[81]	-3	hSpCas9	negative selection	10785154
159917516	159917539	5	-	28162770	PL21	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-1.866974581369217	[175]	[20]	-8	hSpCas9	negative selection	10785155
159917066	159917089	5	-	28162770	PL21	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.3606042866825663	[203]	[113]	3	hSpCas9	negative selection	10785156
159917174	159917197	5	-	28162770	PL21	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	0.07984538077160852	[99]	[45]	0	hSpCas9	negative selection	10785157
159917318	159917341	5	-	28162770	P31FUJ	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	-0.08374639501966552	[293]	[325]	-1	hSpCas9	negative selection	10954514
159917199	159917222	5	-	28162770	P31FUJ	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	0.13116111027019595	[114]	[147]	1	hSpCas9	negative selection	10954515
159917423	159917446	5	-	28162770	P31FUJ	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.7821481370515927	[191]	[387]	8	hSpCas9	negative selection	10954516
159917443	159917466	5	-	28162770	P31FUJ	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.7111637606712934	[209]	[403]	7	hSpCas9	negative selection	10954517
159917598	159917621	5	+	28162770	P31FUJ	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.9731724574881069	[100]	[232]	9	hSpCas9	negative selection	10954518
159916997	159917020	5	-	28162770	P31FUJ	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	0.7421068146227909	[57]	[113]	8	hSpCas9	negative selection	10954519
159917016	159917039	5	+	28162770	P31FUJ	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.5696502189222213	[378]	[660]	6	hSpCas9	negative selection	10954520
159917516	159917539	5	-	28162770	P31FUJ	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-3.72634167737194	[213]	[18]	-9	hSpCas9	negative selection	10954521
159917066	159917089	5	-	28162770	P31FUJ	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	1.0127505018413034	[255]	[606]	9	hSpCas9	negative selection	10954522
159917174	159917197	5	-	28162770	P31FUJ	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	0.3708968588883632	[101]	[154]	4	hSpCas9	negative selection	10954523
159917318	159917341	5	-	28162770	OCIAML5	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.7328959298571593	[141]	[425]	6	hSpCas9	negative selection	11123880
159917199	159917222	5	-	28162770	OCIAML5	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	-0.7767784435597598	[55]	[58]	-5	hSpCas9	negative selection	11123881
159917423	159917446	5	-	28162770	OCIAML5	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.6110375869840596	[106]	[294]	5	hSpCas9	negative selection	11123882
159917443	159917466	5	-	28162770	OCIAML5	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.7606409203400635	[102]	[314]	6	hSpCas9	negative selection	11123883
159917598	159917621	5	+	28162770	OCIAML5	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.10270417514300534	[80]	[156]	0	hSpCas9	negative selection	11123884
159916997	159917020	5	-	28162770	OCIAML5	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	0.4780820308283338	[34]	[87]	4	hSpCas9	negative selection	11123885
159917016	159917039	5	+	28162770	OCIAML5	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.4436564536759716	[199]	[490]	4	hSpCas9	negative selection	11123886
159917516	159917539	5	-	28162770	OCIAML5	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-2.4005031955600393	[116]	[39]	-8	hSpCas9	negative selection	11123887
159917066	159917089	5	-	28162770	OCIAML5	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.8635253725096422	[101]	[334]	7	hSpCas9	negative selection	11123888
159917174	159917197	5	-	28162770	OCIAML5	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	0.23539627038634228	[111]	[237]	2	hSpCas9	negative selection	11123889
159917318	159917341	5	-	28162770	EOL1	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.29772595052122386	[541]	[350]	2	hSpCas9	negative selection	11293246
159917199	159917222	5	-	28162770	EOL1	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	-0.041504896506127764	[83]	[42]	0	hSpCas9	negative selection	11293247
159917423	159917446	5	-	28162770	EOL1	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.5180074489682309	[394]	[297]	5	hSpCas9	negative selection	11293248
159917443	159917466	5	-	28162770	EOL1	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	1.5542219210980834	[412]	[638]	9	hSpCas9	negative selection	11293249
159917598	159917621	5	+	28162770	EOL1	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	1.321346152564336	[198]	[261]	9	hSpCas9	negative selection	11293250
159916997	159917020	5	-	28162770	EOL1	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-0.3555601476222008	[101]	[41]	-3	hSpCas9	negative selection	11293251
159917016	159917039	5	+	28162770	EOL1	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.4593696282440982	[282]	[204]	4	hSpCas9	negative selection	11293252
159917516	159917539	5	-	28162770	EOL1	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-1.3636971970605392	[253]	[51]	-7	hSpCas9	negative selection	11293253
159917066	159917089	5	-	28162770	EOL1	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.48001897558229123	[312]	[229]	4	hSpCas9	negative selection	11293254
159917174	159917197	5	-	28162770	EOL1	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	0.6323670200772243	[119]	[97]	5	hSpCas9	negative selection	11293255
159917318	159917341	5	-	28162770	MOLM13	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	1.5184046527988255	[448]	[929]	9	hSpCas9	negative selection	11462612
159917199	159917222	5	-	28162770	MOLM13	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	-0.0971735617388727	[107]	[72]	0	hSpCas9	negative selection	11462613
159917423	159917446	5	-	28162770	MOLM13	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.49039678095414824	[317]	[322]	3	hSpCas9	negative selection	11462614
159917443	159917466	5	-	28162770	MOLM13	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	1.1656843784301074	[335]	[544]	8	hSpCas9	negative selection	11462615
159917598	159917621	5	+	28162770	MOLM13	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	1.2260256755863956	[229]	[388]	8	hSpCas9	negative selection	11462616
159916997	159917020	5	-	28162770	MOLM13	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-0.35377337719690893	[75]	[42]	-2	hSpCas9	negative selection	11462617
159917016	159917039	5	+	28162770	MOLM13	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	-0.7914972472740707	[394]	[164]	-4	hSpCas9	negative selection	11462618
159917516	159917539	5	-	28162770	MOLM13	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-3.427641351899392	[252]	[16]	-8	hSpCas9	negative selection	11462619
159917066	159917089	5	-	28162770	MOLM13	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.22730982653848092	[305]	[258]	1	hSpCas9	negative selection	11462620
159917174	159917197	5	-	28162770	MOLM13	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	-0.1915230683364585	[168]	[106]	-1	hSpCas9	negative selection	11462621
159917318	159917341	5	-	28162770	HEL	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	1.3504737148428085	[348]	[569]	9	hSpCas9	negative selection	11631978
159917199	159917222	5	-	28162770	HEL	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	-1.0011173577743677	[99]	[31]	-6	hSpCas9	negative selection	11631979
159917423	159917446	5	-	28162770	HEL	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.19527985502913559	[314]	[230]	1	hSpCas9	negative selection	11631980
159917443	159917466	5	-	28162770	HEL	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	1.4946401930112232	[286]	[517]	9	hSpCas9	negative selection	11631981
159917598	159917621	5	+	28162770	HEL	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.4596727308699782	[192]	[169]	4	hSpCas9	negative selection	11631982
159916997	159917020	5	-	28162770	HEL	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	1.2072372301617973	[70]	[104]	9	hSpCas9	negative selection	11631983
159917016	159917039	5	+	28162770	HEL	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	-0.18886363630392455	[314]	[176]	-1	hSpCas9	negative selection	11631984
159917516	159917539	5	-	28162770	HEL	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-0.6382813193067994	[225]	[92]	-4	hSpCas9	negative selection	11631985
159917066	159917089	5	-	28162770	HEL	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.2956401613780885	[317]	[249]	2	hSpCas9	negative selection	11631986
159917174	159917197	5	-	28162770	HEL	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	-0.7320059613304537	[152]	[58]	-5	hSpCas9	negative selection	11631987
159917318	159917341	5	-	28162770	MV411	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.40394203646276594	[287]	[320]	3	hSpCas9	negative selection	11801344
159917199	159917222	5	-	28162770	MV411	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	0.9172889490904446	[43]	[69]	8	hSpCas9	negative selection	11801345
159917423	159917446	5	-	28162770	MV411	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	-0.4847509031215589	[200]	[120]	-4	hSpCas9	negative selection	11801346
159917443	159917466	5	-	28162770	MV411	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.29262632454903076	[219]	[226]	2	hSpCas9	negative selection	11801347
159917598	159917621	5	+	28162770	MV411	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	-1.062417711804012	[118]	[47]	-6	hSpCas9	negative selection	11801348
159916997	159917020	5	-	28162770	MV411	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	1.8165461003030945	[60]	[180]	9	hSpCas9	negative selection	11801349
159917016	159917039	5	+	28162770	MV411	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.1334813614856895	[236]	[218]	1	hSpCas9	negative selection	11801350
159917516	159917539	5	-	28162770	MV411	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-4.3867684689582305	[148]	[5]	-9	hSpCas9	negative selection	11801351
159917066	159917089	5	-	28162770	MV411	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	-0.27088775690809047	[274]	[191]	-2	hSpCas9	negative selection	11801352
159917174	159917197	5	-	28162770	MV411	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	-0.47635265463569754	[108]	[65]	-4	hSpCas9	negative selection	11801353
159917318	159917341	5	-	28162770	MONOMAC1	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.5761110834132985	[188]	[322]	5	hSpCas9	negative selection	11970710
159917199	159917222	5	-	28162770	MONOMAC1	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	1.1469175541578078	[38]	[98]	8	hSpCas9	negative selection	11970711
159917423	159917446	5	-	28162770	MONOMAC1	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.5511560025299066	[127]	[214]	5	hSpCas9	negative selection	11970712
159917443	159917466	5	-	28162770	MONOMAC1	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	0.45813465594300534	[126]	[199]	4	hSpCas9	negative selection	11970713
159917598	159917621	5	+	28162770	MONOMAC1	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	1.1880850743150027	[66]	[174]	9	hSpCas9	negative selection	11970714
159916997	159917020	5	-	28162770	MONOMAC1	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-0.06377031619608942	[30]	[33]	0	hSpCas9	negative selection	11970715
159917016	159917039	5	+	28162770	MONOMAC1	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.01401803034261348	[145]	[168]	0	hSpCas9	negative selection	11970716
159917516	159917539	5	-	28162770	MONOMAC1	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-1.0533013695981044	[104]	[57]	-7	hSpCas9	negative selection	11970717
159917066	159917089	5	-	28162770	MONOMAC1	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.0626069695734659	[141]	[169]	0	hSpCas9	negative selection	11970718
159917174	159917197	5	-	28162770	MONOMAC1	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	0.8276252071747154	[57]	[117]	7	hSpCas9	negative selection	11970719
159917318	159917341	5	-	28162770	OCIAML2	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	0.5902524169048611	[57]	[483]	6	hSpCas9	negative selection	12140076
159917199	159917222	5	-	28162770	OCIAML2	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	0.2039698879636711	[12]	[82]	2	hSpCas9	negative selection	12140077
159917423	159917446	5	-	28162770	OCIAML2	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	0.550188646265393	[42]	[348]	5	hSpCas9	negative selection	12140078
159917443	159917466	5	-	28162770	OCIAML2	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	1.262086295922687	[33]	[451]	9	hSpCas9	negative selection	12140079
159917598	159917621	5	+	28162770	OCIAML2	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	0.31364148370240164	[26]	[185]	3	hSpCas9	negative selection	12140080
159916997	159917020	5	-	28162770	OCIAML2	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	-1.108059745857453	[13]	[35]	-6	hSpCas9	negative selection	12140081
159917016	159917039	5	+	28162770	OCIAML2	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	0.20744207987047641	[44]	[287]	2	hSpCas9	negative selection	12140082
159917516	159917539	5	-	28162770	OCIAML2	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-3.236164571605138	[50]	[29]	-9	hSpCas9	negative selection	12140083
159917066	159917089	5	-	28162770	OCIAML2	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	0.83002965289155	[40]	[403]	7	hSpCas9	negative selection	12140084
159917174	159917197	5	-	28162770	OCIAML2	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	0.0819111977866176	[14]	[87]	0	hSpCas9	negative selection	12140085
159917318	159917341	5	-	28162770	OCIAML3	viability	GATGTAGCGATCGATGGAGATGG	ADRA1B	ENSG00000170214	-0.16337328599430068	[68]	[185]	-1	hSpCas9	negative selection	12309442
159917199	159917222	5	-	28162770	OCIAML3	viability	CTAGGGCCGCTGAGAAGGGCAGG	ADRA1B	ENSG00000170214	1.3082956857887034	[20]	[156]	9	hSpCas9	negative selection	12309443
159917423	159917446	5	-	28162770	OCIAML3	viability	AGGCCCGATGGAGATGACGGTGG	ADRA1B	ENSG00000170214	1.2835083531508418	[42]	[315]	9	hSpCas9	negative selection	12309444
159917443	159917466	5	-	28162770	OCIAML3	viability	GGCTCCTTCCACCCAAGGAGAGG	ADRA1B	ENSG00000170214	-0.1880152806483265	[79]	[211]	-1	hSpCas9	negative selection	12309445
159917598	159917621	5	+	28162770	OCIAML3	viability	GAGAACCACCAAGAACCTAGAGG	ADRA1B	ENSG00000170214	1.2804614775919778	[23]	[175]	9	hSpCas9	negative selection	12309446
159916997	159917020	5	-	28162770	OCIAML3	viability	GGGCAGTGTGGAGTTGCTCGAGG	ADRA1B	ENSG00000170214	1.0930530480157292	[24]	[160]	8	hSpCas9	negative selection	12309447
159917016	159917039	5	+	28162770	OCIAML3	viability	GCCCCAGCTGGACATCACCAGGG	ADRA1B	ENSG00000170214	1.355677895025142	[61]	[478]	9	hSpCas9	negative selection	12309448
159917516	159917539	5	-	28162770	OCIAML3	viability	GGAGCCCAGAGAGGAGAAGAGGG	ADRA1B	ENSG00000170214	-1.594007640324163	[35]	[35]	-8	hSpCas9	negative selection	12309449
159917066	159917089	5	-	28162770	OCIAML3	viability	CACGATGGCAAAGAGGATGAAGG	ADRA1B	ENSG00000170214	1.6969885950113084	[65]	[645]	9	hSpCas9	negative selection	12309450
159917174	159917197	5	-	28162770	OCIAML3	viability	GGTGAAGCTCAACAGCAGGTCGG	ADRA1B	ENSG00000170214	0.1353447697321679	[18]	[62]	1	hSpCas9	negative selection	12309451