Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:146
• Symbol:ADRA1D
• Description:adrenoceptor alpha 1D

DataSource: http://genomecrispr.dkfz.de/#!/results/ADRA1D

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
4248418	4248441	20	+	26472758	Jiyoye	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	4.4221257229718445	[5]	[96]	9	hSpCas9	negative selection	3439
4248040	4248063	20	+	26472758	Jiyoye	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.8152170398305747	[181]	[38]	-8	hSpCas9	negative selection	3440
4248163	4248186	20	+	26472758	Jiyoye	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.7345373624438639	[211]	[265]	5	hSpCas9	negative selection	3441
4248748	4248771	20	-	26472758	Jiyoye	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	1.4775647093972715	[19]	[41]	8	hSpCas9	negative selection	3442
4248702	4248725	20	-	26472758	Jiyoye	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.7608123361205741	[17]	[22]	5	hSpCas9	negative selection	3443
4248475	4248498	20	+	26472758	Jiyoye	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	0.7670713265922563	[119]	[153]	5	hSpCas9	negative selection	3444
4248378	4248401	20	+	26472758	Jiyoye	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-1.3741843320187863	[219]	[63]	-7	hSpCas9	negative selection	3445
4248265	4248288	20	+	26472758	Jiyoye	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.7918392317411986	[71]	[93]	5	hSpCas9	negative selection	3446
4248087	4248110	20	-	26472758	Jiyoye	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	5.930737337562886	[0]	[45]	9	hSpCas9	negative selection	3447
4248051	4248074	20	-	26472758	Jiyoye	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	-1.3006438670008162	[48]	[14]	-7	hSpCas9	negative selection	3448
4248418	4248441	20	+	26472758	KBM7	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-0.4113127046508464	[539,388]	[118,200]	-4	hSpCas9	negative selection	194557
4248040	4248063	20	+	26472758	KBM7	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.1195336655946413	[969,598]	[128,199]	-7	hSpCas9	negative selection	194558
4248163	4248186	20	+	26472758	KBM7	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.6797266667299897	[822,579]	[529,513]	7	hSpCas9	negative selection	194559
4248748	4248771	20	-	26472758	KBM7	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	0.9871366741374556	[54,36]	[37,45]	9	hSpCas9	negative selection	194560
4248702	4248725	20	-	26472758	KBM7	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	1.3289141515398373	[135,70]	[110,125]	9	hSpCas9	negative selection	194561
4248475	4248498	20	+	26472758	KBM7	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-0.7665559073809638	[639,430]	[168,124]	-6	hSpCas9	negative selection	194562
4248378	4248401	20	+	26472758	KBM7	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	0.37979945782512814	[308,394]	[207,228]	4	hSpCas9	negative selection	194563
4248265	4248288	20	+	26472758	KBM7	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.0638922534225887	[733,432]	[372,197]	0	hSpCas9	negative selection	194564
4248087	4248110	20	-	26472758	KBM7	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	1.1207543096728967	[58,100]	[76,90]	9	hSpCas9	negative selection	194565
4248051	4248074	20	-	26472758	KBM7	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	1.0747979714609786	[138,103]	[172,70]	9	hSpCas9	negative selection	194566
4248418	4248441	20	+	26472758	Raji	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	0.30002861331599534	[188]	[53]	3	hSpCas9	negative selection	385675
4248040	4248063	20	+	26472758	Raji	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-0.7623084422806694	[401]	[54]	-5	hSpCas9	negative selection	385676
4248163	4248186	20	+	26472758	Raji	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.9580948266255855	[294]	[132]	8	hSpCas9	negative selection	385677
4248748	4248771	20	-	26472758	Raji	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	-1.2145445595137634	[29]	[2]	-7	hSpCas9	negative selection	385678
4248702	4248725	20	-	26472758	Raji	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.9553804419285497	[39]	[17]	8	hSpCas9	negative selection	385679
4248475	4248498	20	+	26472758	Raji	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-1.2682551462585305	[300]	[28]	-7	hSpCas9	negative selection	385680
4248378	4248401	20	+	26472758	Raji	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	0.8069886020358784	[132]	[53]	7	hSpCas9	negative selection	385681
4248265	4248288	20	+	26472758	Raji	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.11743720003752256	[285]	[71]	1	hSpCas9	negative selection	385682
4248087	4248110	20	-	26472758	Raji	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	0.9109863225700963	[54]	[23]	8	hSpCas9	negative selection	385683
4248051	4248074	20	-	26472758	Raji	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	1.3297759567100473	[47]	[27]	9	hSpCas9	negative selection	385684
4248418	4248441	20	+	26472758	K562	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-1.801517556500412	[350]	[84]	-7	hSpCas9	negative selection	576793
4248040	4248063	20	+	26472758	K562	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.139888152372602	[448]	[171]	-6	hSpCas9	negative selection	576794
4248163	4248186	20	+	26472758	K562	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	-0.012856408878662018	[599]	[501]	0	hSpCas9	negative selection	576795
4248748	4248771	20	-	26472758	K562	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	1.7125675634048532	[29]	[82]	9	hSpCas9	negative selection	576796
4248702	4248725	20	-	26472758	K562	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	1.1564710283907442	[92]	[174]	8	hSpCas9	negative selection	576797
4248475	4248498	20	+	26472758	K562	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-2.4560209904746455	[363]	[55]	-8	hSpCas9	negative selection	576798
4248378	4248401	20	+	26472758	K562	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	0.7893543345160268	[267]	[390]	6	hSpCas9	negative selection	576799
4248265	4248288	20	+	26472758	K562	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.6194445843475241	[383]	[210]	-4	hSpCas9	negative selection	576800
4248087	4248110	20	-	26472758	K562	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	0.09241563422139687	[179]	[161]	0	hSpCas9	negative selection	576801
4248051	4248074	20	-	26472758	K562	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	-0.4336531774461909	[119]	[74]	-3	hSpCas9	negative selection	576802
4221591	4221614	20	-	26627737	DLD1	viability	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.08489133852927502	[573]	[127,168,204]	-1	hSpCas9	negative selection	814594
4221668	4221691	20	-	26627737	DLD1	viability	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.4787464972472541	[353]	[23,91,116]	-5	hSpCas9	negative selection	814595
4221670	4221693	20	-	26627737	DLD1	viability	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.4602366315594344	[436]	[311,121,134]	5	hSpCas9	negative selection	814596
4248265	4248288	20	+	26627737	DLD1	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.26087972780986474	[329]	[135,39,80]	-3	hSpCas9	negative selection	814620
4248441	4248464	20	+	26627737	DLD1	viability	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.2927642710496851	[388]	[192,196,70]	3	hSpCas9	negative selection	814621
4248537	4248560	20	-	26627737	DLD1	viability	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.05935560256188077	[674]	[290,265,119]	0	hSpCas9	negative selection	814622
4221591	4221614	20	-	26627737	GBM cells	viability after 5 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.42901296062311994	[240]	[101,89]	-6	hSpCas9	negative selection	896909
4221668	4221691	20	-	26627737	GBM cells	viability after 5 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.6307055919916957	[178]	[52,70]	-7	hSpCas9	negative selection	896910
4221670	4221693	20	-	26627737	GBM cells	viability after 5 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.19264507794239588	[216]	[125,139]	3	hSpCas9	negative selection	896911
4248265	4248288	20	+	26627737	GBM cells	viability after 5 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.4077474633483663	[187]	[72,78]	-6	hSpCas9	negative selection	896935
4248441	4248464	20	+	26627737	GBM cells	viability after 5 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.03459071332740782	[211]	[127,93]	0	hSpCas9	negative selection	896936
4248537	4248560	20	-	26627737	GBM cells	viability after 5 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.7325554884635657	[201]	[202,156]	8	hSpCas9	negative selection	896937
4221591	4221614	20	-	26627737	GBM cells	viability after 13 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.4807185023765439	[240]	[128,64]	-5	hSpCas9	negative selection	979224
4221668	4221691	20	-	26627737	GBM cells	viability after 13 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.7015561830118229	[178]	[51,65]	-7	hSpCas9	negative selection	979225
4221670	4221693	20	-	26627737	GBM cells	viability after 13 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	-0.29658664755173436	[216]	[91,98]	-4	hSpCas9	negative selection	979226
4248265	4248288	20	+	26627737	GBM cells	viability after 13 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.2213958562384346	[187]	[108,69]	-3	hSpCas9	negative selection	979250
4248441	4248464	20	+	26627737	GBM cells	viability after 13 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.14061033611312473	[211]	[144,111]	1	hSpCas9	negative selection	979251
4248537	4248560	20	-	26627737	GBM cells	viability after 13 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.6921562977822825	[201]	[202,155]	8	hSpCas9	negative selection	979252
4221591	4221614	20	-	26627737	GBM cells	viability after 21 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-1.3275996904028409	[240]	[59,44]	-8	hSpCas9	negative selection	1061539
4221668	4221691	20	-	26627737	GBM cells	viability after 21 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.8510717388577627	[178]	[55,51]	-6	hSpCas9	negative selection	1061540
4221670	4221693	20	-	26627737	GBM cells	viability after 21 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.06717909004206624	[216]	[134,112]	0	hSpCas9	negative selection	1061541
4248265	4248288	20	+	26627737	GBM cells	viability after 21 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.505321378089088	[187]	[72,70]	-4	hSpCas9	negative selection	1061565
4248441	4248464	20	+	26627737	GBM cells	viability after 21 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.6552299401528665	[211]	[69,75]	-5	hSpCas9	negative selection	1061566
4248537	4248560	20	-	26627737	GBM cells	viability after 21 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.8682004782709449	[201]	[227,174]	8	hSpCas9	negative selection	1061567
4221591	4221614	20	-	26627737	RPE1	viability after 9 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-1.034947735658657	[1229]	[152,232]	-6	hSpCas9	negative selection	1143854
4221668	4221691	20	-	26627737	RPE1	viability after 9 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-1.3928596957693427	[578]	[51,90]	-7	hSpCas9	negative selection	1143855
4221670	4221693	20	-	26627737	RPE1	viability after 9 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.5546376604468558	[363]	[107,243]	4	hSpCas9	negative selection	1143856
4248265	4248288	20	+	26627737	RPE1	viability after 9 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-1.301354235772313	[635]	[37,135]	-7	hSpCas9	negative selection	1143880
4248441	4248464	20	+	26627737	RPE1	viability after 9 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.22866044614845132	[896]	[257,215]	-2	hSpCas9	negative selection	1143881
4248537	4248560	20	-	26627737	RPE1	viability after 9 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.15674100346288197	[872]	[236,391]	1	hSpCas9	negative selection	1143882
4221591	4221614	20	-	26627737	RPE1	viability after 12 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-1.370909732655241	[1229]	[102,153]	-7	hSpCas9	negative selection	1226169
4221668	4221691	20	-	26627737	RPE1	viability after 12 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-1.5904121808458775	[578]	[73,27]	-8	hSpCas9	negative selection	1226170
4221670	4221693	20	-	26627737	RPE1	viability after 12 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.6639092095446838	[363]	[118,192]	4	hSpCas9	negative selection	1226171
4248265	4248288	20	+	26627737	RPE1	viability after 12 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-1.266443979503699	[635]	[54,87]	-7	hSpCas9	negative selection	1226195
4248441	4248464	20	+	26627737	RPE1	viability after 12 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.18104887419569618	[896]	[214,209]	-1	hSpCas9	negative selection	1226196
4248537	4248560	20	-	26627737	RPE1	viability after 12 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	-0.012905485043768483	[872]	[247,215]	0	hSpCas9	negative selection	1226197
4221591	4221614	20	-	26627737	RPE1	viability after 15 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.5338732127392354	[1229]	[165,311]	-3	hSpCas9	negative selection	1308484
4221668	4221691	20	-	26627737	RPE1	viability after 15 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-2.0675092258710808	[578]	[62,15]	-8	hSpCas9	negative selection	1308485
4221670	4221693	20	-	26627737	RPE1	viability after 15 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.6510816559406336	[363]	[206,117]	4	hSpCas9	negative selection	1308486
4248265	4248288	20	+	26627737	RPE1	viability after 15 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-1.0774870087268575	[635]	[42,125]	-6	hSpCas9	negative selection	1308510
4248441	4248464	20	+	26627737	RPE1	viability after 15 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.5050233278665792	[896]	[161,194]	-3	hSpCas9	negative selection	1308511
4248537	4248560	20	-	26627737	RPE1	viability after 15 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	-0.07758476905670117	[872]	[288,180]	0	hSpCas9	negative selection	1308512
4221591	4221614	20	-	26627737	RPE1	viability after 18 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-1.1321194619038564	[1229]	[76,230]	-6	hSpCas9	negative selection	1390799
4221668	4221691	20	-	26627737	RPE1	viability after 18 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-1.184388881398204	[578]	[46,91]	-6	hSpCas9	negative selection	1390800
4221670	4221693	20	-	26627737	RPE1	viability after 18 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	1.8240113329872405	[363]	[414,275]	8	hSpCas9	negative selection	1390801
4248265	4248288	20	+	26627737	RPE1	viability after 18 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-2.543007357768957	[635]	[27,30]	-8	hSpCas9	negative selection	1390825
4248441	4248464	20	+	26627737	RPE1	viability after 18 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.4377355734966777	[896]	[155,202]	-3	hSpCas9	negative selection	1390826
4248537	4248560	20	-	26627737	RPE1	viability after 18 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	-0.21962443581313712	[872]	[240,160]	-1	hSpCas9	negative selection	1390827
4221591	4221614	20	-	26627737	HeLa	viability after 8 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	0.1231334713496901	[287]	[184,155,82]	1	hSpCas9	negative selection	1473114
4221668	4221691	20	-	26627737	HeLa	viability after 8 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.5042425796166887	[500]	[184,173,111]	-5	hSpCas9	negative selection	1473115
4221670	4221693	20	-	26627737	HeLa	viability after 8 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.5130471872706631	[394]	[314,202,233]	4	hSpCas9	negative selection	1473116
4248265	4248288	20	+	26627737	HeLa	viability after 8 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.43507256392977633	[211]	[112,39,61]	-4	hSpCas9	negative selection	1473140
4248441	4248464	20	+	26627737	HeLa	viability after 8 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.36419515483433007	[130]	[72,87,59]	3	hSpCas9	negative selection	1473141
4248537	4248560	20	-	26627737	HeLa	viability after 8 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.5173749277315374	[285]	[268,145,141]	4	hSpCas9	negative selection	1473142
4221591	4221614	20	-	26627737	HeLa	viability after 12 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.10561085043939733	[287]	[187,54,96]	-1	hSpCas9	negative selection	1555429
4221668	4221691	20	-	26627737	HeLa	viability after 12 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	0.04629718361861368	[500]	[274,205,162]	0	hSpCas9	negative selection	1555430
4221670	4221693	20	-	26627737	HeLa	viability after 12 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.7302368528174032	[394]	[346,219,252]	6	hSpCas9	negative selection	1555431
4248265	4248288	20	+	26627737	HeLa	viability after 12 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.3351711969391067	[211]	[12,94,95]	-3	hSpCas9	negative selection	1555455
4248441	4248464	20	+	26627737	HeLa	viability after 12 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	1.0355604832054484	[130]	[16,244,53]	7	hSpCas9	negative selection	1555456
4248537	4248560	20	-	26627737	HeLa	viability after 12 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	1.019935724120911	[285]	[280,222,217]	7	hSpCas9	negative selection	1555457
4221591	4221614	20	-	26627737	HeLa	viability after 15 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	0.8473069403087601	[287]	[307,34,294]	6	hSpCas9	negative selection	1637744
4221668	4221691	20	-	26627737	HeLa	viability after 15 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.17423142719694876	[500]	[125,247,167]	-1	hSpCas9	negative selection	1637745
4221670	4221693	20	-	26627737	HeLa	viability after 15 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.6945962649046906	[394]	[385,206,179]	5	hSpCas9	negative selection	1637746
4248265	4248288	20	+	26627737	HeLa	viability after 15 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.1276635697218258	[211]	[69,96,117]	1	hSpCas9	negative selection	1637770
4248441	4248464	20	+	26627737	HeLa	viability after 15 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	1.0485186847630676	[130]	[152,131,39]	7	hSpCas9	negative selection	1637771
4248537	4248560	20	-	26627737	HeLa	viability after 15 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.9086083498624213	[285]	[192,256,204]	7	hSpCas9	negative selection	1637772
4221591	4221614	20	-	26627737	HeLa	viability after 18 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	0.8736370072653918	[287]	[210,32,294]	6	hSpCas9	negative selection	1720059
4221668	4221691	20	-	26627737	HeLa	viability after 18 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.20249968235515384	[500]	[81,199,167]	-2	hSpCas9	negative selection	1720060
4221670	4221693	20	-	26627737	HeLa	viability after 18 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.6455682612732867	[394]	[247,163,179]	5	hSpCas9	negative selection	1720061
4248265	4248288	20	+	26627737	HeLa	viability after 18 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.18757908608543605	[211]	[50,84,117]	1	hSpCas9	negative selection	1720085
4248441	4248464	20	+	26627737	HeLa	viability after 18 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.9733204467457912	[130]	[95,103,39]	7	hSpCas9	negative selection	1720086
4248537	4248560	20	-	26627737	HeLa	viability after 18 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.9176106103558259	[285]	[131,212,204]	7	hSpCas9	negative selection	1720087
4221591	4221614	20	-	26627737	HCT116	viability after 6 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.5952005277740011	[845]	[127,65]	-3	hSpCas9	negative selection	1802374
4221668	4221691	20	-	26627737	HCT116	viability after 6 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-1.248572588520197	[630]	[82,18]	-6	hSpCas9	negative selection	1802375
4221670	4221693	20	-	26627737	HCT116	viability after 6 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.6950869279863854	[709]	[346,88]	4	hSpCas9	negative selection	1802376
4248265	4248288	20	+	26627737	HCT116	viability after 6 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.7798849603423819	[560]	[129,7]	-4	hSpCas9	negative selection	1802400
4248441	4248464	20	+	26627737	HCT116	viability after 6 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	1.3671618004062593	[212]	[213,15]	7	hSpCas9	negative selection	1802401
4248537	4248560	20	-	26627737	HCT116	viability after 6 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.32004074386682435	[781]	[137,161]	1	hSpCas9	negative selection	1802402
4221591	4221614	20	-	26627737	HCT116	viability after 8 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.7385090914863924	[297]	[98,75,119]	-7	hSpCas9	negative selection	1884689
4221668	4221691	20	-	26627737	HCT116	viability after 8 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.5611770950143493	[354]	[185,105,106]	-6	hSpCas9	negative selection	1884690
4221670	4221693	20	-	26627737	HCT116	viability after 8 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.9670027458101749	[248]	[273,202,326]	8	hSpCas9	negative selection	1884691
4248265	4248288	20	+	26627737	HCT116	viability after 8 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.45456790498703614	[174]	[103,82,207]	5	hSpCas9	negative selection	1884715
4248441	4248464	20	+	26627737	HCT116	viability after 8 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.5524089012829082	[251]	[52,109,119]	-6	hSpCas9	negative selection	1884716
4248537	4248560	20	-	26627737	HCT116	viability after 8 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	1.4370071999609757	[106]	[133,146,196]	9	hSpCas9	negative selection	1884717
4221591	4221614	20	-	26627737	HCT116	viability after 9 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-1.6932148883654063	[845]	[137,15]	-8	hSpCas9	negative selection	1967004
4221668	4221691	20	-	26627737	HCT116	viability after 9 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	0.10649560185393003	[630]	[334,59]	0	hSpCas9	negative selection	1967005
4221670	4221693	20	-	26627737	HCT116	viability after 9 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.6453124763219437	[709]	[95,454]	5	hSpCas9	negative selection	1967006
4248265	4248288	20	+	26627737	HCT116	viability after 9 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.1835173522293876	[560]	[106,219]	1	hSpCas9	negative selection	1967030
4248441	4248464	20	+	26627737	HCT116	viability after 9 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	2.61870348558834	[212]	[164,494]	9	hSpCas9	negative selection	1967031
4248537	4248560	20	-	26627737	HCT116	viability after 9 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.5532629523982843	[781]	[478,169]	4	hSpCas9	negative selection	1967032
4221591	4221614	20	-	26627737	HCT116	viability after 12 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.32303013775287115	[297]	[132,129,111]	-3	hSpCas9	negative selection	2049319
4221668	4221691	20	-	26627737	HCT116	viability after 12 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.4163126598179554	[354]	[173,164,77]	-4	hSpCas9	negative selection	2049320
4221670	4221693	20	-	26627737	HCT116	viability after 12 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	1.5263787455989082	[248]	[390,351,385]	9	hSpCas9	negative selection	2049321
4248265	4248288	20	+	26627737	HCT116	viability after 12 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.26146004466610706	[174]	[124,133,70]	2	hSpCas9	negative selection	2049345
4248441	4248464	20	+	26627737	HCT116	viability after 12 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.07129607525017279	[251]	[194,158,58]	0	hSpCas9	negative selection	2049346
4248537	4248560	20	-	26627737	HCT116	viability after 12 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	1.5642340530978707	[106]	[190,178,126]	9	hSpCas9	negative selection	2049347
4221591	4221614	20	-	26627737	HCT116	viability after 15 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.5204883553673982	[297]	[162,143,56]	-5	hSpCas9	negative selection	2131634
4221668	4221691	20	-	26627737	HCT116	viability after 15 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.8134993664542995	[354]	[120,142,84]	-7	hSpCas9	negative selection	2131635
4221670	4221693	20	-	26627737	HCT116	viability after 15 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	1.1821378584048454	[248]	[450,225,311]	8	hSpCas9	negative selection	2131636
4248265	4248288	20	+	26627737	HCT116	viability after 15 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.7494583263376248	[174]	[111,38,34]	-6	hSpCas9	negative selection	2131660
4248441	4248464	20	+	26627737	HCT116	viability after 15 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.43650391634439845	[251]	[185,256,143]	4	hSpCas9	negative selection	2131661
4248537	4248560	20	-	26627737	HCT116	viability after 15 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	1.6116782339339666	[106]	[197,209,156]	9	hSpCas9	negative selection	2131662
4221591	4221614	20	-	26627737	HCT116	viability after 18 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.6595508199310252	[297]	[98,118,51]	-6	hSpCas9	negative selection	2213949
4221668	4221691	20	-	26627737	HCT116	viability after 18 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-1.0902434452965766	[354]	[76,131,26]	-7	hSpCas9	negative selection	2213950
4221670	4221693	20	-	26627737	HCT116	viability after 18 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	1.1791002592763145	[248]	[258,412,129]	8	hSpCas9	negative selection	2213951
4248265	4248288	20	+	26627737	HCT116	viability after 18 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.12435910269701034	[174]	[108,90,75]	1	hSpCas9	negative selection	2213975
4248441	4248464	20	+	26627737	HCT116	viability after 18 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.26995113867236975	[251]	[146,125,24]	-2	hSpCas9	negative selection	2213976
4248537	4248560	20	-	26627737	HCT116	viability after 18 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	1.9758694062810167	[106]	[189,289,120]	9	hSpCas9	negative selection	2213977
4233053	4233076	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTACTTGGGAGGCTGAGGCGAG	ADRA1D	ENSG00000171873	-0.3390870473927914	[36,5]	[4,0]	-1	dCas9-VP64	positive selection	2411776
4233053	4233076	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTACTTGGGAGGCTGAGGCGAG	ADRA1D	ENSG00000171873	0.46536086309934765	[31,100]	[53,5]	3	dCas9-VP64	positive selection	2507031
4248748	4248771	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	0.5838961951455187	[3,2]	[2,5]	9	hSpCas9	positive selection	2969201
4248207	4248230	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGCTTCTGCGGTATCACCGAGG	ADRA1D	ENSG00000171873	-0.33123083358190736	[3,2]	[2,1]	-5	hSpCas9	positive selection	2969202
4248680	4248703	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCACCACCAGTCCCCCGACGG	ADRA1D	ENSG00000171873	0.010810460831697288	[3,2]	[4,0]	0	hSpCas9	positive selection	2969203
4248537	4248560	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.25939271901725924	[4,4]	[5,4]	5	hSpCas9	positive selection	2969204
4248748	4248771	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	-0.1271627268994519	[3,3]	[3,0]	-2	hSpCas9	positive selection	3037059
4248207	4248230	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGCTTCTGCGGTATCACCGAGG	ADRA1D	ENSG00000171873	-0.16290281505885512	[3,3]	[4,0]	-2	hSpCas9	positive selection	3037060
4248680	4248703	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCACCACCAGTCCCCCGACGG	ADRA1D	ENSG00000171873	0.4283109367592625	[3,3]	[3,2]	7	hSpCas9	positive selection	3037061
4248537	4248560	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.25407552802380645	[4,4]	[5,2]	4	hSpCas9	positive selection	3037062
4248215	4248238		+	24336571	A375	resistance to PLX after 7 days	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.029936903880566766	[12,11]	[12,11]	1	hSpCas9	positive selection	3107236
4221671	4221694		-	24336571	A375	resistance to PLX after 7 days	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.14995124869261112	[7,7]	[7,9]	5	hSpCas9	positive selection	3107247
4221676	4221699		+	24336571	A375	resistance to PLX after 7 days	GCGGATCTTGTGCGACAGGCTGG	ADRA1D	ENSG00000171873	-0.11427507177019258	[7,6]	[7,5]	-4	hSpCas9	positive selection	3107258
4248111	4248134		+	24336571	A375	resistance to PLX after 7 days	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.09347360918628	[20,18]	[21,15]	-3	hSpCas9	positive selection	3107269
4248215	4248238		+	24336571	A375	resistance to PLX after 14 days	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.44957599179408164	[16,12]	[5,12]	4	hSpCas9	positive selection	3165029
4221671	4221694		-	24336571	A375	resistance to PLX after 14 days	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.24069625715911525	[6,5]	[2,1]	-3	hSpCas9	positive selection	3165040
4221676	4221699		+	24336571	A375	resistance to PLX after 14 days	GCGGATCTTGTGCGACAGGCTGG	ADRA1D	ENSG00000171873	0.041484728366459	[5,4]	[2,1]	0	hSpCas9	positive selection	3165051
4248111	4248134		+	24336571	A375	resistance to PLX after 14 days	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.04693354177848208	[22,18]	[11,6]	0	hSpCas9	positive selection	3165062
4248215	4248238		+	24336571	A375	viability after 7 days	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.6416437279420741	[7]	[12,11]	8	hSpCas9	negative selection	3222822
4221671	4221694		-	24336571	A375	viability after 7 days	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.05765712063290174	[8]	[7,7]	-1	hSpCas9	negative selection	3222833
4221676	4221699		+	24336571	A375	viability after 7 days	GCGGATCTTGTGCGACAGGCTGG	ADRA1D	ENSG00000171873	0.41750308922293045	[5]	[7,6]	6	hSpCas9	negative selection	3222844
4248111	4248134		+	24336571	A375	viability after 7 days	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.6017506551478915	[13]	[20,18]	8	hSpCas9	negative selection	3222855
4248215	4248238		+	24336571	A375	viability after 14 days	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.8949084390325075	[7]	[16,12]	9	hSpCas9	negative selection	3280615
4221671	4221694		-	24336571	A375	viability after 14 days	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.3156309870622155	[8]	[6,5]	-4	hSpCas9	negative selection	3280626
4221676	4221699		+	24336571	A375	viability after 14 days	GCGGATCTTGTGCGACAGGCTGG	ADRA1D	ENSG00000171873	0.02151464712849238	[5]	[5,4]	0	hSpCas9	negative selection	3280637
4248111	4248134		+	24336571	A375	viability after 14 days	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.6875854297981706	[13]	[22,18]	8	hSpCas9	negative selection	3280648
4248215	4248238	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.9910295918154562	[72,80]	[0,0]	4	hSpCas9	positive selection	3335782
4248111	4248134	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.8463830364116612	[98,70]	[0,0]	4	hSpCas9	positive selection	3335783
4221671	4221694	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.1486651034678587	[139,135]	[0,0]	0	hSpCas9	positive selection	3335784
4222085	4222108	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.12637808102821713	[166,166]	[0,0]	0	hSpCas9	positive selection	3355031
4248218	4248241	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	1.672363710724679	[47,47]	[0,0]	6	hSpCas9	positive selection	3355032
4248442	4248465	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	-0.819489385604996	[269,269]	[0,0]	-5	hSpCas9	positive selection	3355033
4248748	4248771	20	-	26780180	HT29	viability (Avana library 4 designs)	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	1.83898888540999	[]	[]	7	hSpCas9	negative selection	3405265
4248207	4248230	20	-	26780180	HT29	viability (Avana library 4 designs)	GCGCTTCTGCGGTATCACCGAGG	ADRA1D	ENSG00000171873	0.606899369950382	[]	[]	2	hSpCas9	negative selection	3405266
4248679	4248702	20	+	26780180	HT29	viability (Avana library 4 designs)	GCTCACCACCAGTCCCCCGACGG	ADRA1D	ENSG00000171873	0.711857328753767	[]	[]	2	hSpCas9	negative selection	3405267
4248537	4248560	20	-	26780180	HT29	viability (Avana library 4 designs)	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.0388167993179258	[]	[]	0	hSpCas9	negative selection	3405268
4248537	4248560	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	5.43953307373198	[]	[]	8	hSpCas9	negative selection	3477192
4248207	4248230	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGCTTCTGCGGTATCACCGAGG	ADRA1D	ENSG00000171873	5.14729133307942	[]	[]	8	hSpCas9	negative selection	3477193
4248748	4248771	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	5.52014943231648	[]	[]	8	hSpCas9	negative selection	3477194
4248679	4248702	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCACCACCAGTCCCCCGACGG	ADRA1D	ENSG00000171873	0.753616770441	[]	[]	1	hSpCas9	negative selection	3477195
4248747	4248770	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGACAACCGGAGCTCCGCGGGGG	ADRA1D	ENSG00000171873	2.77368245749161	[]	[]	4	hSpCas9	negative selection	3477196
4248702	4248725	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	3.47016254372588	[]	[]	5	hSpCas9	negative selection	3477197
4248537	4248560	20	-	26780180	A375	viability (Avana lentiGuide)	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	-3.62295807278554	[]	[]	-6	hSpCas9	negative selection	3585851
4248207	4248230	20	-	26780180	A375	viability (Avana lentiGuide)	GCGCTTCTGCGGTATCACCGAGG	ADRA1D	ENSG00000171873	-4.32885798613433	[]	[]	-7	hSpCas9	negative selection	3585852
4248748	4248771	20	-	26780180	A375	viability (Avana lentiGuide)	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	-2.13094290756451	[]	[]	-4	hSpCas9	negative selection	3585853
4248679	4248702	20	+	26780180	A375	viability (Avana lentiGuide)	GCTCACCACCAGTCCCCCGACGG	ADRA1D	ENSG00000171873	2.51541369770308	[]	[]	2	hSpCas9	negative selection	3585854
4248747	4248770	20	-	26780180	A375	viability (Avana lentiGuide)	GGACAACCGGAGCTCCGCGGGGG	ADRA1D	ENSG00000171873	-1.20416996224289	[]	[]	-2	hSpCas9	negative selection	3585855
4248702	4248725	20	-	26780180	A375	viability (Avana lentiGuide)	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	1.84127875322381	[]	[]	2	hSpCas9	negative selection	3585856
4248537	4248560	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.3245793449944816	[5]	[7,6]	8	hSpCas9	positive selection	3694510
4248207	4248230	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGCTTCTGCGGTATCACCGAGG	ADRA1D	ENSG00000171873	0.1347728506257529	[4]	[4,4]	3	hSpCas9	positive selection	3694511
4248748	4248771	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	0.34107867495131267	[4]	[5,4]	8	hSpCas9	positive selection	3694512
4248679	4248702	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCACCACCAGTCCCCCGACGG	ADRA1D	ENSG00000171873	-0.13121226006756698	[4]	[4,2]	-2	hSpCas9	positive selection	3694513
4248747	4248770	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACAACCGGAGCTCCGCGGGGG	ADRA1D	ENSG00000171873	0.2770719920677088	[5]	[6,5]	7	hSpCas9	positive selection	3694514
4248702	4248725	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.17506976853460823	[3]	[4,3]	5	hSpCas9	positive selection	3694515
4248537	4248560	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.19876437014545417	[6]	[6,5]	5	hSpCas9	positive selection	3803117
4248207	4248230	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGCTTCTGCGGTATCACCGAGG	ADRA1D	ENSG00000171873	-0.030054480900213135	[5]	[4,4]	0	hSpCas9	positive selection	3803118
4248748	4248771	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	-0.4007207169675253	[4]	[2,2]	-5	hSpCas9	positive selection	3803119
4248679	4248702	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCACCACCAGTCCCCCGACGG	ADRA1D	ENSG00000171873	0.2505707533742306	[4]	[5,4]	6	hSpCas9	positive selection	3803120
4248747	4248770	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACAACCGGAGCTCCGCGGGGG	ADRA1D	ENSG00000171873	0.2376162357032715	[5]	[6,5]	6	hSpCas9	positive selection	3803121
4248702	4248725	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	-0.23016624534268365	[4]	[4,1]	-3	hSpCas9	positive selection	3803122
4222085	4222108	20	+	26780180	A375	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	1.01866559662148	[]	[]	5	hSpCas9	negative selection	3911580
4248215	4248238	20	+	26780180	A375	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	1.33144964715508	[]	[]	7	hSpCas9	negative selection	3911581
4248218	4248241	20	-	26780180	A375	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.501992126884627	[]	[]	1	hSpCas9	negative selection	3911582
4221671	4221694	20	-	26780180	A375	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	1.61262179149866	[]	[]	8	hSpCas9	negative selection	3911583
4248442	4248465	20	-	26780180	A375	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.582996510691713	[]	[]	1	hSpCas9	negative selection	3911584
4248111	4248134	20	+	26780180	A375	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	1.22201845518123	[]	[]	6	hSpCas9	negative selection	3911585
4222085	4222108	20	+	26780180	HT29	viability (GeCKOv2 library)	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.139696932655118	[]	[]	-4	hSpCas9	negative selection	4019546
4248215	4248238	20	+	26780180	HT29	viability (GeCKOv2 library)	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	1.14916880948764	[]	[]	5	hSpCas9	negative selection	4019547
4248218	4248241	20	-	26780180	HT29	viability (GeCKOv2 library)	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.437905547707963	[]	[]	1	hSpCas9	negative selection	4019548
4221671	4221694	20	-	26780180	HT29	viability (GeCKOv2 library)	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	1.46022382000202	[]	[]	7	hSpCas9	negative selection	4019549
4248442	4248465	20	-	26780180	HT29	viability (GeCKOv2 library)	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.546435684382156	[]	[]	1	hSpCas9	negative selection	4019550
4248111	4248134	20	+	26780180	HT29	viability (GeCKOv2 library)	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.813731112593635	[]	[]	3	hSpCas9	negative selection	4019551
4248215	4248238	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.16392660904646708	[3]	[1,2]	4	hSpCas9	positive selection	4129479
4221671	4221694	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.607117520644338	[3]	[1,0]	-9	hSpCas9	positive selection	4129490
4221676	4221699	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGGATCTTGTGCGACAGGCTGG	ADRA1D	ENSG00000171873	-0.3194875921092366	[2]	[1,0]	-7	hSpCas9	positive selection	4129501
4248111	4248134	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.34413548852603243	[3]	[2,3]	8	hSpCas9	positive selection	4129512
4248215	4248238	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	1.1655703698186608	[2]	[1,1,0,3]	8	hSpCas9	positive selection	4193501
4221671	4221694	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.30776013440665784	[3]	[4,1,1,0]	2	hSpCas9	positive selection	4193512
4221676	4221699	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGGATCTTGTGCGACAGGCTGG	ADRA1D	ENSG00000171873	0.5942167352097822	[2]	[0,3,0,0]	4	hSpCas9	positive selection	4193523
4248111	4248134	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	1.167688778374806	[3]	[1,0,1,5]	8	hSpCas9	positive selection	4193534
4248215	4248238	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.14402216692110315	[3]	[3,2]	3	hSpCas9	positive selection	4254746
4248111	4248134	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.012776606751554814	[2]	[3,0]	0	hSpCas9	positive selection	4254747
4221671	4221694	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.43538272006538425	[3]	[1,1]	-7	hSpCas9	positive selection	4254748
4222085	4222108	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.17196700169497495	[3]	[2,1]	-3	hSpCas9	positive selection	4319028
4248218	4248241	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	-0.16072442235872464	[2]	[2,0]	-3	hSpCas9	positive selection	4319029
4248442	4248465	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.6054279802169125	[3]	[4,3]	9	hSpCas9	positive selection	4319030
4248112	4248134	20	+	27760321	OCIAML3	viability	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.2699929484311384	[864,672]	[493,496]	-3	hSpCas9	negative selection	4376516
4248217	4248239	20	+	27760321	OCIAML3	viability	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	-0.31118444577512266	[518,471]	[266,370]	-3	hSpCas9	negative selection	4376517
4248321	4248343	20	-	27760321	OCIAML3	viability	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.0973975561259216	[779,741]	[719,529]	1	hSpCas9	negative selection	4376518
4248432	4248454	20	-	27760321	OCIAML3	viability	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	-0.011620452455871844	[997,837]	[629,812]	0	hSpCas9	negative selection	4376519
4248695	4248717	20	-	27760321	OCIAML3	viability	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.5025439763046831	[1030,869]	[1116,960]	6	hSpCas9	negative selection	4376520
4248112	4248134	20	+	27760321	OCIAML2	viability	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.31324782866260914	[864,672]	[663,903]	4	hSpCas9	negative selection	4459979
4248217	4248239	20	+	27760321	OCIAML2	viability	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	-0.31791930613915476	[518,471]	[225,446]	-4	hSpCas9	negative selection	4459980
4248321	4248343	20	-	27760321	OCIAML2	viability	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.12609964956477215	[779,741]	[531,857]	1	hSpCas9	negative selection	4459981
4248432	4248454	20	-	27760321	OCIAML2	viability	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	-0.005568353828564021	[997,837]	[625,882]	0	hSpCas9	negative selection	4459982
4248695	4248717	20	-	27760321	OCIAML2	viability	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.37978698150466483	[1030,869]	[878,1151]	5	hSpCas9	negative selection	4459983
4248112	4248134	20	+	27760321	MV411	viability	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-1.097075065660003	[864,672]	[197,291]	-6	hSpCas9	negative selection	4543442
4248217	4248239	20	+	27760321	MV411	viability	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	-0.5197134431468416	[518,471]	[147,347]	-4	hSpCas9	negative selection	4543443
4248321	4248343	20	-	27760321	MV411	viability	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.8835338584841086	[779,741]	[708,1255]	6	hSpCas9	negative selection	4543444
4248432	4248454	20	-	27760321	MV411	viability	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.2808063985672613	[997,837]	[623,896]	2	hSpCas9	negative selection	4543445
4248695	4248717	20	-	27760321	MV411	viability	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	1.039835544404776	[1030,869]	[1359,1171]	7	hSpCas9	negative selection	4543446
4248112	4248134	20	+	27760321	HL60	viability	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.6615046931436757	[864,672]	[406,380]	-6	hSpCas9	negative selection	4626905
4248217	4248239	20	+	27760321	HL60	viability	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	-0.017843478566930776	[518,471]	[400,397]	0	hSpCas9	negative selection	4626906
4248321	4248343	20	-	27760321	HL60	viability	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	-0.6944056634081945	[779,741]	[421,344]	-6	hSpCas9	negative selection	4626907
4248432	4248454	20	-	27760321	HL60	viability	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	-0.02585519095004729	[997,837]	[707,760]	0	hSpCas9	negative selection	4626908
4248695	4248717	20	-	27760321	HL60	viability	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.22800114893393753	[1030,869]	[807,1009]	2	hSpCas9	negative selection	4626909
4248112	4248134	20	+	27760321	HT1080	viability	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.09180340959923539	[672,524]	[242,202]	0	hSpCas9	negative selection	4710368
4248217	4248239	20	+	27760321	HT1080	viability	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	0.6234188675831402	[471,368]	[280,232]	3	hSpCas9	negative selection	4710369
4248321	4248343	20	-	27760321	HT1080	viability	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.6165005593513069	[741,578]	[432,370]	3	hSpCas9	negative selection	4710370
4248432	4248454	20	-	27760321	HT1080	viability	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.3455679709283004	[837,653]	[358,397]	1	hSpCas9	negative selection	4710371
4248695	4248717	20	-	27760321	HT1080	viability	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.6514068139472229	[869,678]	[307,677]	3	hSpCas9	negative selection	4710372
4248112	4248134	20	+	27760321	HT29	viability after 7 days	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.40353471471232116	[672,524]	[988,1032,1027]	6	hSpCas9	negative selection	4793831
4248217	4248239	20	+	27760321	HT29	viability after 7 days	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	-0.0014485140303922006	[471,368]	[607,596,427]	0	hSpCas9	negative selection	4793832
4248321	4248343	20	-	27760321	HT29	viability after 7 days	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	-0.025108267609015633	[741,578]	[1324,686,568]	0	hSpCas9	negative selection	4793833
4248432	4248454	20	-	27760321	HT29	viability after 7 days	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.22625396088226246	[837,653]	[1518,812,1089]	3	hSpCas9	negative selection	4793834
4248695	4248717	20	-	27760321	HT29	viability after 7 days	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.2676912629341599	[869,678]	[1401,1351,879]	4	hSpCas9	negative selection	4793835
4248112	4248134	20	+	27760321	HT29	viability after 25 days	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.6202887751203787	[672,524]	[863,1000,1330]	7	hSpCas9	negative selection	4877294
4248217	4248239	20	+	27760321	HT29	viability after 25 days	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	0.24968816511018088	[471,368]	[667,504,529]	2	hSpCas9	negative selection	4877295
4248321	4248343	20	-	27760321	HT29	viability after 25 days	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.30802439192804854	[741,578]	[777,839,1223]	3	hSpCas9	negative selection	4877296
4248432	4248454	20	-	27760321	HT29	viability after 25 days	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.5099735225553552	[837,653]	[938,1147,1611]	5	hSpCas9	negative selection	4877297
4248695	4248717	20	-	27760321	HT29	viability after 25 days	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.6333877507915033	[869,678]	[1541,1115,1456]	7	hSpCas9	negative selection	4877298
4248112	4248134	20	+	27760321	HT29	viability after 22 days	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.6002901539126668	[672,524]	[854,783,1519]	6	hSpCas9	negative selection	4960757
4248217	4248239	20	+	27760321	HT29	viability after 22 days	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	0.4513764176445185	[471,368]	[734,629,626]	5	hSpCas9	negative selection	4960758
4248321	4248343	20	-	27760321	HT29	viability after 22 days	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.6515695774979515	[741,578]	[1155,1192,1250]	7	hSpCas9	negative selection	4960759
4248432	4248454	20	-	27760321	HT29	viability after 22 days	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.35401534314440597	[837,653]	[980,1122,1206]	4	hSpCas9	negative selection	4960760
4248695	4248717	20	-	27760321	HT29	viability after 22 days	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.7928264657438509	[869,678]	[1565,1752,1331]	8	hSpCas9	negative selection	4960761
4248112	4248134	20	+	27760321	HT29	viability after 19 days	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.6461890086590509	[672,524]	[802,1541,850]	6	hSpCas9	negative selection	5044220
4248217	4248239	20	+	27760321	HT29	viability after 19 days	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	0.4736714181700338	[471,368]	[528,746,710]	5	hSpCas9	negative selection	5044221
4248321	4248343	20	-	27760321	HT29	viability after 19 days	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.6775686114020483	[741,578]	[958,1116,1509]	7	hSpCas9	negative selection	5044222
4248432	4248454	20	-	27760321	HT29	viability after 19 days	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.3201579446395024	[837,653]	[1120,1104,977]	3	hSpCas9	negative selection	5044223
4248695	4248717	20	-	27760321	HT29	viability after 19 days	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.36404236014704194	[869,678]	[1137,1299,986]	3	hSpCas9	negative selection	5044224
4248112	4248134	20	+	27760321	HT29	viability after 16 days	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.39718501734489187	[672,524]	[999,750,910]	4	hSpCas9	negative selection	5127683
4248217	4248239	20	+	27760321	HT29	viability after 16 days	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	0.07478118495138197	[471,368]	[452,476,552]	0	hSpCas9	negative selection	5127684
4248321	4248343	20	-	27760321	HT29	viability after 16 days	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.5613484816809193	[741,578]	[912,722,1627]	6	hSpCas9	negative selection	5127685
4248432	4248454	20	-	27760321	HT29	viability after 16 days	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.46238231797440044	[837,653]	[968,1172,1289]	5	hSpCas9	negative selection	5127686
4248695	4248717	20	-	27760321	HT29	viability after 16 days	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.19763388406218985	[869,678]	[1157,1014,822]	2	hSpCas9	negative selection	5127687
4248112	4248134	20	+	27760321	HT29	viability after 13 days	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.5092975630214003	[672,524]	[672,934,1337]	6	hSpCas9	negative selection	5211146
4248217	4248239	20	+	27760321	HT29	viability after 13 days	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	0.3676361963153769	[471,368]	[813,616,466]	4	hSpCas9	negative selection	5211147
4248321	4248343	20	-	27760321	HT29	viability after 13 days	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.45972595735499144	[741,578]	[1250,1030,888]	6	hSpCas9	negative selection	5211148
4248432	4248454	20	-	27760321	HT29	viability after 13 days	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.1610343017389908	[837,653]	[841,1041,1015]	2	hSpCas9	negative selection	5211149
4248695	4248717	20	-	27760321	HT29	viability after 13 days	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.3699137339623253	[869,678]	[1095,1391,1004]	5	hSpCas9	negative selection	5211150
4248112	4248134	20	+	27760321	HT29	viability after 10 days	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.06446286955364111	[672,524]	[635,947,766]	0	hSpCas9	negative selection	5294609
4248217	4248239	20	+	27760321	HT29	viability after 10 days	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	0.38483202913734516	[471,368]	[673,877,513]	5	hSpCas9	negative selection	5294610
4248321	4248343	20	-	27760321	HT29	viability after 10 days	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.5647664605956682	[741,578]	[1411,1109,1135]	7	hSpCas9	negative selection	5294611
4248432	4248454	20	-	27760321	HT29	viability after 10 days	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.016818353720233548	[837,653]	[990,822,1007]	0	hSpCas9	negative selection	5294612
4248695	4248717	20	-	27760321	HT29	viability after 10 days	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.4460920676541815	[869,678]	[1002,1598,1356]	6	hSpCas9	negative selection	5294613
4248112	4248134	20	+	27760321	MOLM13	viability	GCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.1445100683410524	[864,672]	[459,329]	-1	hSpCas9	negative selection	5378072
4248217	4248239	20	+	27760321	MOLM13	viability	ACCGCAGAAGCGCTCGTCAGGG	ADRA1D	ENSG00000171873	-0.3429116221396844	[518,471]	[276,171]	-2	hSpCas9	negative selection	5378073
4248321	4248343	20	-	27760321	MOLM13	viability	GCCATCATGACCGAGCGCAAGG	ADRA1D	ENSG00000171873	0.2779205039657895	[779,741]	[625,431]	2	hSpCas9	negative selection	5378074
4248432	4248454	20	-	27760321	MOLM13	viability	TGCGACGTATGGGCCGCCGTGG	ADRA1D	ENSG00000171873	0.4055343297453473	[997,837]	[462,870]	3	hSpCas9	negative selection	5378075
4248695	4248717	20	-	27760321	MOLM13	viability	TGAATGGCACGGCGGCCGTCGG	ADRA1D	ENSG00000171873	0.0780404742306966	[1030,869]	[637,500]	0	hSpCas9	negative selection	5378076
4248496	4248519	20	+	27661255	K562	viability	GGCCGAGAAGGGCAGTACGGTGG	ADRA1D	ENSG00000171873	0.1489317315958068	[584,720]	[627,531]	5	dCas9-KRAB	negative selection	5461183
4248582	4248605	20	+	27661255	K562	viability	GGCGGTTGCAGGCCACTGAGAGG	ADRA1D	ENSG00000171873	0.21003212254638326	[945,1126]	[985,927]	7	dCas9-KRAB	negative selection	5461184
4248839	4248862	20	-	27661255	K562	viability	GGCGGCGCGGCCCCCTCGGAGGG	ADRA1D	ENSG00000171873	-0.628602667386657	[1105,1380]	[728,563]	-8	dCas9-KRAB	negative selection	5461185
4248215	4248238	20	+	27260156	BXPC3	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.15116226113915238	[489]	[420,413,398,635]	-3	hSpCas9	negative selection	5527206
4248111	4248134	20	+	27260156	BXPC3	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.3946103961197416	[396]	[239,354,269,412]	-7	hSpCas9	negative selection	5527207
4221671	4221694	20	-	27260156	BXPC3	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.26482835019073975	[575]	[510,446,473,580]	-6	hSpCas9	negative selection	5527208
4222085	4222108	20	+	27260156	BXPC3	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.42790922426798095	[520]	[275,423,444,496]	-7	hSpCas9	negative selection	5591488
4248218	4248241	20	-	27260156	BXPC3	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.129905502394578	[221]	[266,290,192,258]	3	hSpCas9	negative selection	5591489
4248442	4248465	20	-	27260156	BXPC3	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.3457150351404463	[481]	[594,699,467,813]	7	hSpCas9	negative selection	5591490
4248215	4248238	20	+	27260156	A673	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.1922265615540981	[489]	[611,400,569,487]	-5	hSpCas9	negative selection	5648457
4248111	4248134	20	+	27260156	A673	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.6334207144483515	[396]	[323,301,307,295]	-9	hSpCas9	negative selection	5648458
4221671	4221694	20	-	27260156	A673	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.02296982156745403	[575]	[880,585,537,746]	0	hSpCas9	negative selection	5648459
4222085	4222108	20	+	27260156	A673	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.18536428528286386	[520]	[570,531,554,543]	-4	hSpCas9	negative selection	5712739
4248218	4248241	20	-	27260156	A673	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.5020755409719109	[221]	[367,428,292,419]	9	hSpCas9	negative selection	5712740
4248442	4248465	20	-	27260156	A673	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.2713779991430546	[481]	[646,689,670,783]	6	hSpCas9	negative selection	5712741
4248215	4248238	20	+	27260156	A375	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.11807845928142377	[489]	[857,680,570,407]	1	hSpCas9	negative selection	5769708
4248111	4248134	20	+	27260156	A375	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.4007784249879004	[396]	[338,453,349,282]	-5	hSpCas9	negative selection	5769709
4221671	4221694	20	-	27260156	A375	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.07653552328857915	[575]	[774,840,632,615]	1	hSpCas9	negative selection	5769710
4222085	4222108	20	+	27260156	A375	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.30971382873462716	[520]	[356,580,604,436]	-4	hSpCas9	negative selection	5833990
4248218	4248241	20	-	27260156	A375	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.641261386422435	[221]	[412,587,423,236]	8	hSpCas9	negative selection	5833991
4248442	4248465	20	-	27260156	A375	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.5653250327297514	[481]	[718,884,1107,645]	8	hSpCas9	negative selection	5833992
4248215	4248238	20	+	27260156	COLO741	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.024558144576170317	[489]	[510,702,621]	0	hSpCas9	negative selection	5890959
4248111	4248134	20	+	27260156	COLO741	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.3096700701485411	[396]	[425,486,321]	-6	hSpCas9	negative selection	5890960
4221671	4221694	20	-	27260156	COLO741	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.016780684952151348	[575]	[824,770,649]	0	hSpCas9	negative selection	5890961
4222085	4222108	20	+	27260156	COLO741	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.3045887363923107	[520]	[562,602,457]	-6	hSpCas9	negative selection	5955241
4248218	4248241	20	-	27260156	COLO741	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.26820506358194574	[221]	[552,264,231]	5	hSpCas9	negative selection	5955242
4248442	4248465	20	-	27260156	COLO741	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.3116439888790473	[481]	[726,890,676]	6	hSpCas9	negative selection	5955243
4248215	4248238	20	+	27260156	CAL120	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.35908778018554266	[489]	[636,264,546]	-5	hSpCas9	negative selection	6012210
4248111	4248134	20	+	27260156	CAL120	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.029528751463305802	[396]	[748,330,412]	0	hSpCas9	negative selection	6012211
4221671	4221694	20	-	27260156	CAL120	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.010979058950634446	[575]	[1026,670,517]	0	hSpCas9	negative selection	6012212
4222085	4222108	20	+	27260156	CAL120	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.12367572842961894	[520]	[676,565,554]	-2	hSpCas9	negative selection	6076492
4248218	4248241	20	-	27260156	CAL120	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.14496401875413978	[221]	[370,299,255]	2	hSpCas9	negative selection	6076493
4248442	4248465	20	-	27260156	CAL120	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.0781925219957084	[481]	[545,638,699]	1	hSpCas9	negative selection	6076494
4248215	4248238	20	+	27260156	CADOES1	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.15715059756041255	[489]	[365,556,410,296]	-3	hSpCas9	negative selection	6133461
4248111	4248134	20	+	27260156	CADOES1	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.5761699003580804	[396]	[231,201,297,258]	-7	hSpCas9	negative selection	6133462
4221671	4221694	20	-	27260156	CADOES1	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.04056530878172915	[575]	[523,641,414,501]	0	hSpCas9	negative selection	6133463
4222085	4222108	20	+	27260156	CADOES1	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.0718199472434035	[520]	[417,361,245,831]	-1	hSpCas9	negative selection	6197743
4248218	4248241	20	-	27260156	CADOES1	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.11770667645568	[221]	[244,210,241,196]	2	hSpCas9	negative selection	6197744
4248442	4248465	20	-	27260156	CADOES1	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.40749757551783716	[481]	[631,646,566,529]	6	hSpCas9	negative selection	6197745
4248215	4248238	20	+	27260156	EWS502	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.012185277840984436	[489]	[640,490,424,519]	0	hSpCas9	negative selection	6254712
4248111	4248134	20	+	27260156	EWS502	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.15945697594923736	[396]	[372,196,518,428]	-3	hSpCas9	negative selection	6254713
4221671	4221694	20	-	27260156	EWS502	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.13095687112063858	[575]	[574,768,692,637]	2	hSpCas9	negative selection	6254714
4222085	4222108	20	+	27260156	EWS502	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.18099754242290553	[520]	[477,405,496,574]	-3	hSpCas9	negative selection	6318994
4248218	4248241	20	-	27260156	EWS502	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.6295577394284069	[221]	[465,345,210,420]	9	hSpCas9	negative selection	6318995
4248442	4248465	20	-	27260156	EWS502	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.2659767848090202	[481]	[470,650,744,602]	4	hSpCas9	negative selection	6318996
4248215	4248238	20	+	27260156	EW8	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.047422273857769474	[489]	[314,256,558,366]	-1	hSpCas9	negative selection	6375963
4248111	4248134	20	+	27260156	EW8	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.016626559833167187	[396]	[499,298,195,316]	0	hSpCas9	negative selection	6375964
4221671	4221694	20	-	27260156	EW8	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.06273006226613312	[575]	[523,472,454,341]	-1	hSpCas9	negative selection	6375965
4222085	4222108	20	+	27260156	EW8	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.033668792486280144	[520]	[515,281,348,522]	0	hSpCas9	negative selection	6440245
4248218	4248241	20	-	27260156	EW8	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.29346886635419733	[221]	[183,266,247,173]	5	hSpCas9	negative selection	6440246
4248442	4248465	20	-	27260156	EW8	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.3099159857508045	[481]	[514,720,404,312]	5	hSpCas9	negative selection	6440247
4248215	4248238	20	+	27260156	CORL105	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.03837088672303231	[489]	[648,476,696,437]	0	hSpCas9	negative selection	6497214
4248111	4248134	20	+	27260156	CORL105	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.22552465276580097	[396]	[476,314,439,368]	-4	hSpCas9	negative selection	6497215
4221671	4221694	20	-	27260156	CORL105	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.07663272317734676	[575]	[570,666,567,736]	-1	hSpCas9	negative selection	6497216
4222085	4222108	20	+	27260156	CORL105	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.2251586627286433	[520]	[586,482,539,482]	-4	hSpCas9	negative selection	6561496
4248218	4248241	20	-	27260156	CORL105	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.13142420742741545	[221]	[269,290,284,291]	2	hSpCas9	negative selection	6561497
4248442	4248465	20	-	27260156	CORL105	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.1222074400672705	[481]	[516,609,840,520]	2	hSpCas9	negative selection	6561498
4248215	4248238	20	+	27260156	HS294T	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.5537507145542935	[489]	[303,319,277,190]	7	hSpCas9	negative selection	6618465
4248111	4248134	20	+	27260156	HS294T	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.4935885012396102	[396]	[62,95,70,230]	-6	hSpCas9	negative selection	6618466
4221671	4221694	20	-	27260156	HS294T	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.14381285512970904	[575]	[150,298,178,384]	2	hSpCas9	negative selection	6618467
4222085	4222108	20	+	27260156	HS294T	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.37332350005104553	[520]	[115,120,196,199]	-5	hSpCas9	negative selection	6682747
4248218	4248241	20	-	27260156	HS294T	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	-0.10968269910787853	[221]	[51,99,92,73]	-1	hSpCas9	negative selection	6682748
4248442	4248465	20	-	27260156	HS294T	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.26676939250327936	[481]	[203,191,154,372]	3	hSpCas9	negative selection	6682749
4248215	4248238	20	+	27260156	HCC44	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.26822829317946273	[489]	[799,566,817,535]	4	hSpCas9	negative selection	6739716
4248111	4248134	20	+	27260156	HCC44	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.13661720394850693	[396]	[820,335,424,430]	2	hSpCas9	negative selection	6739717
4221671	4221694	20	-	27260156	HCC44	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.12049126742409114	[575]	[754,482,717,490]	-2	hSpCas9	negative selection	6739718
4222085	4222108	20	+	27260156	HCC44	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.07074136479245142	[520]	[590,477,715,497]	-1	hSpCas9	negative selection	6803998
4248218	4248241	20	-	27260156	HCC44	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.5145411762925712	[221]	[313,387,366,355]	8	hSpCas9	negative selection	6803999
4248442	4248465	20	-	27260156	HCC44	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.11164254739513577	[481]	[801,443,506,622]	1	hSpCas9	negative selection	6804000
4248215	4248238	20	+	27260156	G402	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.46952789129708555	[489]	[1103,1099,882,302]	6	hSpCas9	negative selection	6860967
4248111	4248134	20	+	27260156	G402	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.53742547161783	[396]	[236,347,409,325]	-6	hSpCas9	negative selection	6860968
4221671	4221694	20	-	27260156	G402	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.7212301209238553	[575]	[556,331,294,527]	-7	hSpCas9	negative selection	6860969
4222085	4222108	20	+	27260156	G402	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.7289557680539983	[520]	[353,401,441,333]	-7	hSpCas9	negative selection	6925249
4248218	4248241	20	-	27260156	G402	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	-0.4642078366026676	[221]	[310,223,159,111]	-5	hSpCas9	negative selection	6925250
4248442	4248465	20	-	27260156	G402	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.7157721034261821	[481]	[965,719,733,1403]	8	hSpCas9	negative selection	6925251
4248215	4248238	20	+	27260156	L33	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.09475065045972852	[489]	[471,199,370,543]	2	hSpCas9	negative selection	6982218
4248111	4248134	20	+	27260156	L33	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.0386403895342598	[396]	[331,180,249,375]	-1	hSpCas9	negative selection	6982219
4221671	4221694	20	-	27260156	L33	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.24166545881883633	[575]	[417,186,365,493]	-5	hSpCas9	negative selection	6982220
4222085	4222108	20	+	27260156	L33	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	0.3739946731311088	[520]	[715,326,336,648]	7	hSpCas9	negative selection	7046500
4248218	4248241	20	-	27260156	L33	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.10059322934615045	[221]	[226,95,146,256]	2	hSpCas9	negative selection	7046501
4248442	4248465	20	-	27260156	L33	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	-0.021159372276933812	[481]	[476,223,351,317]	0	hSpCas9	negative selection	7046502
4248215	4248238	20	+	27260156	K562	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.21116055678855997	[489]	[985,495,418,186]	2	hSpCas9	negative selection	7103469
4248111	4248134	20	+	27260156	K562	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.11230215064865884	[396]	[679,249,143,260]	-1	hSpCas9	negative selection	7103470
4221671	4221694	20	-	27260156	K562	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.2703277244333443	[575]	[377,517,396,403]	-3	hSpCas9	negative selection	7103471
4222085	4222108	20	+	27260156	K562	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.5617793624851845	[520]	[179,275,509,276]	-6	hSpCas9	negative selection	7167751
4248218	4248241	20	-	27260156	K562	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.5165196991914599	[221]	[316,426,142,252]	6	hSpCas9	negative selection	7167752
4248442	4248465	20	-	27260156	K562	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.3147419513815798	[481]	[664,335,617,509]	4	hSpCas9	negative selection	7167753
4248215	4248238	20	+	27260156	HT29	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.23142574881747444	[489]	[739,569,782,691]	4	hSpCas9	negative selection	7224720
4248111	4248134	20	+	27260156	HT29	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.2508702622344832	[396]	[494,296,545,292]	-5	hSpCas9	negative selection	7224721
4221671	4221694	20	-	27260156	HT29	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.07361117619611973	[575]	[881,732,781,575]	1	hSpCas9	negative selection	7224722
4222085	4222108	20	+	27260156	HT29	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.0724508133089638	[520]	[624,532,777,479]	-1	hSpCas9	negative selection	7289002
4248218	4248241	20	-	27260156	HT29	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.4593717765797267	[221]	[318,421,388,353]	8	hSpCas9	negative selection	7289003
4248442	4248465	20	-	27260156	HT29	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.3343950320237753	[481]	[862,735,791,586]	6	hSpCas9	negative selection	7289004
4248215	4248238	20	+	27260156	MHHES1	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.026765967046907008	[489]	[665,657,472,413]	0	hSpCas9	negative selection	7345971
4248111	4248134	20	+	27260156	MHHES1	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.20654719263649107	[396]	[377,465,430,294]	-4	hSpCas9	negative selection	7345972
4221671	4221694	20	-	27260156	MHHES1	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.1919441795900066	[575]	[695,633,657,345]	-4	hSpCas9	negative selection	7345973
4222085	4222108	20	+	27260156	MHHES1	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.07454788007162329	[520]	[599,673,724,296]	-1	hSpCas9	negative selection	7410253
4248218	4248241	20	-	27260156	MHHES1	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.42442917201311925	[221]	[365,368,315,298]	7	hSpCas9	negative selection	7410254
4248442	4248465	20	-	27260156	MHHES1	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.32153886192648773	[481]	[857,722,758,440]	6	hSpCas9	negative selection	7410255
4248215	4248238	20	+	27260156	MEWO	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.12980777899803733	[489]	[453,342,466]	-3	hSpCas9	negative selection	7467222
4248111	4248134	20	+	27260156	MEWO	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.06502781342157707	[396]	[566,206,426]	1	hSpCas9	negative selection	7467223
4221671	4221694	20	-	27260156	MEWO	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.12993779187526805	[575]	[510,469,499]	-3	hSpCas9	negative selection	7467224
4222085	4222108	20	+	27260156	MEWO	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	0.3049812009647581	[520]	[813,481,551]	6	hSpCas9	negative selection	7531504
4248218	4248241	20	-	27260156	MEWO	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.3528890276105656	[221]	[236,309,242]	7	hSpCas9	negative selection	7531505
4248442	4248465	20	-	27260156	MEWO	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.054212846527054895	[481]	[526,449,438]	1	hSpCas9	negative selection	7531506
4248215	4248238	20	+	27260156	LNCAPCLONEFGC	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.09125271313039635	[489]	[463,516,537,378]	1	hSpCas9	negative selection	7588473
4248111	4248134	20	+	27260156	LNCAPCLONEFGC	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.3007558823087121	[396]	[216,285,335,336]	-5	hSpCas9	negative selection	7588474
4221671	4221694	20	-	27260156	LNCAPCLONEFGC	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.06070594252160694	[575]	[336,534,677,477]	-1	hSpCas9	negative selection	7588475
4222085	4222108	20	+	27260156	LNCAPCLONEFGC	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.05690946686981664	[520]	[378,360,641,467]	-1	hSpCas9	negative selection	7652755
4248218	4248241	20	-	27260156	LNCAPCLONEFGC	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.4346548470004522	[221]	[339,225,340,191]	6	hSpCas9	negative selection	7652756
4248442	4248465	20	-	27260156	LNCAPCLONEFGC	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.48993238002108674	[481]	[669,520,691,585]	7	hSpCas9	negative selection	7652757
4248215	4248238	20	+	27260156	PANC0327	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.3146739139679339	[489]	[391,398,365,239]	-5	hSpCas9	negative selection	7709724
4248111	4248134	20	+	27260156	PANC0327	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.4639590855837843	[396]	[122,190,270,434]	-6	hSpCas9	negative selection	7709725
4221671	4221694	20	-	27260156	PANC0327	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.3959151165050019	[575]	[400,375,382,397]	-5	hSpCas9	negative selection	7709726
4222085	4222108	20	+	27260156	PANC0327	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.1807656022492225	[520]	[399,411,433,385]	-3	hSpCas9	negative selection	7774006
4248218	4248241	20	-	27260156	PANC0327	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.14594151087173046	[221]	[115,180,194,376]	2	hSpCas9	negative selection	7774007
4248442	4248465	20	-	27260156	PANC0327	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.6085378488901065	[481]	[520,572,876,639]	8	hSpCas9	negative selection	7774008
4248215	4248238	20	+	27260156	NCIH2009	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.313939298443423	[489]	[1402,506,756]	4	hSpCas9	negative selection	7830975
4248111	4248134	20	+	27260156	NCIH2009	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.10078701163333409	[396]	[536,503,513]	-1	hSpCas9	negative selection	7830976
4221671	4221694	20	-	27260156	NCIH2009	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.06752650531647664	[575]	[1104,857,616]	0	hSpCas9	negative selection	7830977
4222085	4222108	20	+	27260156	NCIH2009	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.2963840657630684	[520]	[621,481,680]	-4	hSpCas9	negative selection	7895257
4248218	4248241	20	-	27260156	NCIH2009	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.2849286162520276	[221]	[401,256,480]	4	hSpCas9	negative selection	7895258
4248442	4248465	20	-	27260156	NCIH2009	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.4900836050897712	[481]	[1190,1077,612]	6	hSpCas9	negative selection	7895259
4248215	4248238	20	+	27260156	NCIH1373	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.4280629656284601	[489]	[1024,549,700,194]	4	hSpCas9	negative selection	7952226
4248111	4248134	20	+	27260156	NCIH1373	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.8871928940049489	[396]	[383,172,187,64]	-7	hSpCas9	negative selection	7952227
4221671	4221694	20	-	27260156	NCIH1373	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.1851999064979004	[575]	[490,409,747,163]	-2	hSpCas9	negative selection	7952228
4222085	4222108	20	+	27260156	NCIH1373	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.40163148953782835	[520]	[857,281,322,100]	-4	hSpCas9	negative selection	8016508
4248218	4248241	20	-	27260156	NCIH1373	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.8612621201188004	[221]	[622,708,164,79]	8	hSpCas9	negative selection	8016509
4248442	4248465	20	-	27260156	NCIH1373	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.37670429073191236	[481]	[860,654,403,244]	4	hSpCas9	negative selection	8016510
4248215	4248238	20	+	27260156	PATU8902	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.5894944276596711	[489]	[1242,745,779,1439]	6	hSpCas9	negative selection	8073477
4248111	4248134	20	+	27260156	PATU8902	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.20669828378894334	[396]	[404,626,243,728]	-2	hSpCas9	negative selection	8073478
4221671	4221694	20	-	27260156	PATU8902	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.49675882649342445	[575]	[945,1205,919,1554]	5	hSpCas9	negative selection	8073479
4222085	4222108	20	+	27260156	PATU8902	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	0.1839787132128409	[520]	[907,462,730,1262]	1	hSpCas9	negative selection	8137759
4248218	4248241	20	-	27260156	PATU8902	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.43082548301019297	[221]	[290,319,409,676]	4	hSpCas9	negative selection	8137760
4248442	4248465	20	-	27260156	PATU8902	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.8794111602901996	[481]	[1289,997,917,1881]	8	hSpCas9	negative selection	8137761
4248215	4248238	20	+	27260156	PANC1	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.14069084562953396	[489]	[372,677,613,263]	2	hSpCas9	negative selection	8194728
4248111	4248134	20	+	27260156	PANC1	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.6380248093884292	[396]	[174,358,241,139]	-7	hSpCas9	negative selection	8194729
4221671	4221694	20	-	27260156	PANC1	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.09692279558467312	[575]	[360,620,398,490]	-1	hSpCas9	negative selection	8194730
4222085	4222108	20	+	27260156	PANC1	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.3738874833912976	[520]	[319,577,294,246]	-5	hSpCas9	negative selection	8259010
4248218	4248241	20	-	27260156	PANC1	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.6717178630342269	[221]	[382,382,363,124]	9	hSpCas9	negative selection	8259011
4248442	4248465	20	-	27260156	PANC1	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.2705641385437353	[481]	[424,654,559,399]	4	hSpCas9	negative selection	8259012
4248215	4248238	20	+	27260156	PANC0813	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.44285526483790055	[489]	[875,688,721,845]	7	hSpCas9	negative selection	8315979
4248111	4248134	20	+	27260156	PANC0813	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.13949197412145597	[396]	[693,283,447,298]	-2	hSpCas9	negative selection	8315980
4221671	4221694	20	-	27260156	PANC0813	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.010569745150537213	[575]	[879,611,603,648]	0	hSpCas9	negative selection	8315981
4222085	4222108	20	+	27260156	PANC0813	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.15752086954744254	[520]	[464,537,522,653]	-3	hSpCas9	negative selection	8380261
4248218	4248241	20	-	27260156	PANC0813	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.28322226470794987	[221]	[470,242,272,296]	4	hSpCas9	negative selection	8380262
4248442	4248465	20	-	27260156	PANC0813	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.49852708653722844	[481]	[762,834,972,633]	7	hSpCas9	negative selection	8380263
4248215	4248238	20	+	27260156	RDES	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.10523573177662601	[489]	[443,435,592,654]	-2	hSpCas9	negative selection	8437230
4248111	4248134	20	+	27260156	RDES	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.41047029108084254	[396]	[253,326,381,437]	-6	hSpCas9	negative selection	8437231
4221671	4221694	20	-	27260156	RDES	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.2389943241869312	[575]	[442,509,628,700]	-4	hSpCas9	negative selection	8437232
4222085	4222108	20	+	27260156	RDES	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.43277506271135757	[520]	[319,462,492,525]	-6	hSpCas9	negative selection	8501512
4248218	4248241	20	-	27260156	RDES	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.3414449747431073	[221]	[280,263,434,322]	5	hSpCas9	negative selection	8501513
4248442	4248465	20	-	27260156	RDES	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.5466829451794244	[481]	[618,703,1033,937]	8	hSpCas9	negative selection	8501514
4248215	4248238	20	+	27260156	PC3	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.18021405335054227	[489]	[267,316,886,468]	-4	hSpCas9	negative selection	8558481
4248111	4248134	20	+	27260156	PC3	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.10893693780181621	[396]	[323,447,745,301]	2	hSpCas9	negative selection	8558482
4221671	4221694	20	-	27260156	PC3	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.0613858635207542	[575]	[375,560,859,748]	1	hSpCas9	negative selection	8558483
4222085	4222108	20	+	27260156	PC3	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.045925201013865394	[520]	[289,438,803,654]	-1	hSpCas9	negative selection	8622763
4248218	4248241	20	-	27260156	PC3	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.4267430232435907	[221]	[147,291,743,218]	8	hSpCas9	negative selection	8622764
4248442	4248465	20	-	27260156	PC3	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.008025286471062619	[481]	[310,611,616,461]	0	hSpCas9	negative selection	8622765
4248215	4248238	20	+	27260156	PATU8988T	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.09361926757380468	[489]	[851,303,374,469]	1	hSpCas9	negative selection	8679732
4248111	4248134	20	+	27260156	PATU8988T	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.1095961941584383	[396]	[479,569,247,370]	2	hSpCas9	negative selection	8679733
4221671	4221694	20	-	27260156	PATU8988T	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.2669481677542328	[575]	[446,424,481,494]	-4	hSpCas9	negative selection	8679734
4222085	4222108	20	+	27260156	PATU8988T	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.31575687597648183	[520]	[380,349,336,557]	-5	hSpCas9	negative selection	8744014
4248218	4248241	20	-	27260156	PATU8988T	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.5800667559615933	[221]	[222,409,393,257]	8	hSpCas9	negative selection	8744015
4248442	4248465	20	-	27260156	PATU8988T	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.5076872760527589	[481]	[619,638,671,719]	8	hSpCas9	negative selection	8744016
4248215	4248238	20	+	27260156	T47D	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.00864692504152547	[489]	[564,629,544,522]	0	hSpCas9	negative selection	8800983
4248111	4248134	20	+	27260156	T47D	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.446172181341693	[396]	[431,254,308,370]	-7	hSpCas9	negative selection	8800984
4221671	4221694	20	-	27260156	T47D	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.12612898616523094	[575]	[589,659,601,602]	-3	hSpCas9	negative selection	8800985
4222085	4222108	20	+	27260156	T47D	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.4777071996996316	[520]	[493,388,423,440]	-7	hSpCas9	negative selection	8865265
4248218	4248241	20	-	27260156	T47D	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.4053385616711651	[221]	[327,368,324,345]	8	hSpCas9	negative selection	8865266
4248442	4248465	20	-	27260156	T47D	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.35312562095617284	[481]	[753,715,652,747]	7	hSpCas9	negative selection	8865267
4248215	4248238	20	+	27260156	SU8686	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.3127391157084598	[489]	[775,431,472,750]	5	hSpCas9	negative selection	8922234
4248111	4248134	20	+	27260156	SU8686	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.2097906934005892	[396]	[213,375,517,250]	-4	hSpCas9	negative selection	8922235
4221671	4221694	20	-	27260156	SU8686	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.10125256050567416	[575]	[550,513,616,816]	1	hSpCas9	negative selection	8922236
4222085	4222108	20	+	27260156	SU8686	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.04327117208000293	[520]	[504,468,554,472]	-1	hSpCas9	negative selection	8986516
4248218	4248241	20	-	27260156	SU8686	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.28475187204234087	[221]	[271,229,268,310]	5	hSpCas9	negative selection	8986517
4248442	4248465	20	-	27260156	SU8686	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.2236627130208194	[481]	[530,495,561,667]	4	hSpCas9	negative selection	8986518
4248215	4248238	20	+	27260156	SKES1	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.0924436918195457	[489]	[528,502,474,349]	-2	hSpCas9	negative selection	9043485
4248111	4248134	20	+	27260156	SKES1	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.34745483640626373	[396]	[465,345,212,250]	-6	hSpCas9	negative selection	9043486
4221671	4221694	20	-	27260156	SKES1	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.20215987941285676	[575]	[513,519,500,465]	-4	hSpCas9	negative selection	9043487
4222085	4222108	20	+	27260156	SKES1	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.08254683646871731	[520]	[580,632,426,362]	-2	hSpCas9	negative selection	9107767
4248218	4248241	20	-	27260156	SKES1	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.4002206468369446	[221]	[327,378,341,148]	7	hSpCas9	negative selection	9107768
4248442	4248465	20	-	27260156	SKES1	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.4359152473809311	[481]	[813,711,590,523]	8	hSpCas9	negative selection	9107769
4248215	4248238	20	+	27260156	TOV112D	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	0.2927559428813203	[489]	[512,603,462,810]	5	hSpCas9	negative selection	9164736
4248111	4248134	20	+	27260156	TOV112D	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	0.3271290200040244	[396]	[359,798,448,449]	6	hSpCas9	negative selection	9164737
4221671	4221694	20	-	27260156	TOV112D	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	0.3482043165851369	[575]	[844,787,671,655]	6	hSpCas9	negative selection	9164738
4222085	4222108	20	+	27260156	TOV112D	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	0.16857257891549235	[520]	[355,1135,534,437]	3	hSpCas9	negative selection	9229018
4248218	4248241	20	-	27260156	TOV112D	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.2773826927043419	[221]	[242,396,246,220]	5	hSpCas9	negative selection	9229019
4248442	4248465	20	-	27260156	TOV112D	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.5076063860874326	[481]	[606,663,594,860]	8	hSpCas9	negative selection	9229020
4248215	4248238	20	+	27260156	TC71	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.17763862518096776	[489]	[404,494,462,497]	-5	hSpCas9	negative selection	9285987
4248111	4248134	20	+	27260156	TC71	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.21847312586860795	[396]	[387,455,306,309]	-5	hSpCas9	negative selection	9285988
4221671	4221694	20	-	27260156	TC71	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.08165546896654274	[575]	[700,562,529,535]	-2	hSpCas9	negative selection	9285989
4222085	4222108	20	+	27260156	TC71	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.033343816139133606	[520]	[561,534,466,625]	-1	hSpCas9	negative selection	9350269
4248218	4248241	20	-	27260156	TC71	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	-0.06545353020791866	[221]	[157,235,269,246]	-2	hSpCas9	negative selection	9350270
4248442	4248465	20	-	27260156	TC71	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.12339101019664214	[481]	[553,518,610,565]	3	hSpCas9	negative selection	9350271
4248215	4248238	20	+	27260156	TC32	viability	ATACCGCAGAAGCGCTCGTCAGG	ADRA1D	ENSG00000171873	-0.014583881838297716	[489]	[426,289,680,507]	0	hSpCas9	negative selection	9407238
4248111	4248134	20	+	27260156	TC32	viability	TGCGCGCGACCACGTACACGCGG	ADRA1D	ENSG00000171873	-0.5023924096661742	[396]	[294,160,358,274]	-7	hSpCas9	negative selection	9407239
4221671	4221694	20	-	27260156	TC32	viability	CTGTCGCACAAGATCCGCGCCGG	ADRA1D	ENSG00000171873	-0.10475068064820067	[575]	[545,272,685,598]	-2	hSpCas9	negative selection	9407240
4222085	4222108	20	+	27260156	TC32	viability	ACCTTGAAGACGCCCTCCGATGG	ADRA1D	ENSG00000171873	-0.474142033355735	[520]	[386,200,524,359]	-7	hSpCas9	negative selection	9471520
4248218	4248241	20	-	27260156	TC32	viability	CCCCCTGACGAGCGCTTCTGCGG	ADRA1D	ENSG00000171873	0.33689835671830703	[221]	[240,201,391,250]	6	hSpCas9	negative selection	9471521
4248442	4248465	20	-	27260156	TC32	viability	GCCGCGCCTTCTGCGACGTATGG	ADRA1D	ENSG00000171873	0.3058658550666231	[481]	[509,363,688,758]	5	hSpCas9	negative selection	9471522
4221591	4221614	20	-	27869803	HPAFII	viability after 27 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.23946734498824668	[295]	[163,104,NaN]	-2	hSpCas9	negative selection	9577654
4221668	4221691	20	-	27869803	HPAFII	viability after 27 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.5938069119500563	[225]	[105,55,NaN]	-4	hSpCas9	negative selection	9577655
4221670	4221693	20	-	27869803	HPAFII	viability after 27 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	-0.281755814135298	[279]	[185,66,NaN]	-2	hSpCas9	negative selection	9577656
4248265	4248288	20	+	27869803	HPAFII	viability after 27 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.4379646550622637	[144]	[118,3,NaN]	-3	hSpCas9	negative selection	9577680
4248441	4248464	20	+	27869803	HPAFII	viability after 27 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.1339104474288912	[216]	[122,126,NaN]	1	hSpCas9	negative selection	9577681
4248537	4248560	20	-	27869803	HPAFII	viability after 27 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	-0.037360254663115544	[254]	[104,151,NaN]	0	hSpCas9	negative selection	9577682
4221591	4221614	20	-	27869803	HPAFII	viability after 15 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.35971448345545215	[295]	[250,245,NaN]	-4	hSpCas9	negative selection	9660103
4221668	4221691	20	-	27869803	HPAFII	viability after 15 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	0.03130669829279567	[225]	[254,243,NaN]	0	hSpCas9	negative selection	9660104
4221670	4221693	20	-	27869803	HPAFII	viability after 15 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.15466867675958165	[279]	[461,255,NaN]	1	hSpCas9	negative selection	9660105
4248265	4248288	20	+	27869803	HPAFII	viability after 15 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.5629291552553964	[144]	[168,65,NaN]	-6	hSpCas9	negative selection	9660129
4248441	4248464	20	+	27869803	HPAFII	viability after 15 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.09732962393191454	[216]	[349,186,NaN]	1	hSpCas9	negative selection	9660130
4248537	4248560	20	-	27869803	HPAFII	viability after 15 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.2941262455879564	[254]	[319,345,NaN]	3	hSpCas9	negative selection	9660131
4221591	4221614	20	-	27869803	ASPC1	viability after 36 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	0.3455313181136286	[671]	[471,176,268]	3	hSpCas9	negative selection	9742552
4221668	4221691	20	-	27869803	ASPC1	viability after 36 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-1.1129220592764113	[491]	[29,85,107]	-8	hSpCas9	negative selection	9742553
4221670	4221693	20	-	27869803	ASPC1	viability after 36 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	-0.6070841801139211	[680]	[487,55,0]	-6	hSpCas9	negative selection	9742554
4248265	4248288	20	+	27869803	ASPC1	viability after 36 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.4155490232827651	[400]	[209,55,68]	-4	hSpCas9	negative selection	9742578
4248441	4248464	20	+	27869803	ASPC1	viability after 36 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.1838677475265113	[390]	[453,39,34]	1	hSpCas9	negative selection	9742579
4248537	4248560	20	-	27869803	ASPC1	viability after 36 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.7711313102229038	[477]	[461,181,238]	7	hSpCas9	negative selection	9742580
4221591	4221614	20	-	27869803	PATU8988S	viability after 35 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	0.05840875823478964	[595]	[230,268,NaN]	0	hSpCas9	negative selection	9825001
4221668	4221691	20	-	27869803	PATU8988S	viability after 35 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	0.10938021858902053	[363]	[222,92,NaN]	1	hSpCas9	negative selection	9825002
4221670	4221693	20	-	27869803	PATU8988S	viability after 35 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.3833496135873222	[554]	[317,264,NaN]	4	hSpCas9	negative selection	9825003
4248265	4248288	20	+	27869803	PATU8988S	viability after 35 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.11668722833828216	[385]	[91,194,NaN]	-1	hSpCas9	negative selection	9825027
4248441	4248464	20	+	27869803	PATU8988S	viability after 35 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.5225990079843823	[331]	[228,154,NaN]	6	hSpCas9	negative selection	9825028
4248537	4248560	20	-	27869803	PATU8988S	viability after 35 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.6384790491290129	[521]	[226,427,NaN]	7	hSpCas9	negative selection	9825029
4221591	4221614	20	-	27869803	PATU8988S	viability after 31 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.004551750536391716	[595]	[151,344,NaN]	0	hSpCas9	negative selection	9907450
4221668	4221691	20	-	27869803	PATU8988S	viability after 31 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.2224426980119234	[363]	[141,101,NaN]	-3	hSpCas9	negative selection	9907451
4221670	4221693	20	-	27869803	PATU8988S	viability after 31 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	0.35290757245364135	[554]	[246,327,NaN]	4	hSpCas9	negative selection	9907452
4248265	4248288	20	+	27869803	PATU8988S	viability after 31 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.04495776647363381	[385]	[94,239,NaN]	0	hSpCas9	negative selection	9907476
4248441	4248464	20	+	27869803	PATU8988S	viability after 31 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	0.3645663325836548	[331]	[180,156,NaN]	4	hSpCas9	negative selection	9907477
4248537	4248560	20	-	27869803	PATU8988S	viability after 31 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.24805377883122426	[521]	[211,291,NaN]	3	hSpCas9	negative selection	9907478
4221591	4221614	20	-	27869803	HPAFII	viability after 35 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.910005826998365	[295]	[43,119,NaN]	-5	hSpCas9	negative selection	9989899
4221668	4221691	20	-	27869803	HPAFII	viability after 35 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.39495029414312366	[225]	[110,59,NaN]	-2	hSpCas9	negative selection	9989900
4221670	4221693	20	-	27869803	HPAFII	viability after 35 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	-1.1497806588108819	[279]	[69,56,NaN]	-6	hSpCas9	negative selection	9989901
4248265	4248288	20	+	27869803	HPAFII	viability after 35 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-1.2846709509380583	[144]	[55,0,NaN]	-6	hSpCas9	negative selection	9989925
4248441	4248464	20	+	27869803	HPAFII	viability after 35 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.42309335437492157	[216]	[64,100,NaN]	-3	hSpCas9	negative selection	9989926
4248537	4248560	20	-	27869803	HPAFII	viability after 35 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	-0.18724956101716209	[254]	[47,186,NaN]	-1	hSpCas9	negative selection	9989927
4221591	4221614	20	-	27869803	HPAFII	viability after 31 days	CCTAGGCGTCCCACACGAGGTGG	ADRA1D	ENSG00000171873	-0.3764042320429608	[295]	[104,152,NaN]	-3	hSpCas9	negative selection	10072348
4221668	4221691	20	-	27869803	HPAFII	viability after 31 days	TCGCACAAGATCCGCGCCGGGGG	ADRA1D	ENSG00000171873	-0.2905356788140665	[225]	[96,110,NaN]	-2	hSpCas9	negative selection	10072349
4221670	4221693	20	-	27869803	HPAFII	viability after 31 days	TGTCGCACAAGATCCGCGCCGGG	ADRA1D	ENSG00000171873	-1.2249092289903776	[279]	[49,85,NaN]	-6	hSpCas9	negative selection	10072350
4248265	4248288	20	+	27869803	HPAFII	viability after 31 days	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-1.2915654118792945	[144]	[60,2,NaN]	-7	hSpCas9	negative selection	10072374
4248441	4248464	20	+	27869803	HPAFII	viability after 31 days	CCCATACGTCGCAGAAGGCGCGG	ADRA1D	ENSG00000171873	-0.6173725247636991	[216]	[87,69,NaN]	-4	hSpCas9	negative selection	10072375
4248537	4248560	20	-	27869803	HPAFII	viability after 31 days	TTTCATCGTGAACCTGGCCGTGG	ADRA1D	ENSG00000171873	0.28130964825557075	[254]	[93,260,NaN]	2	hSpCas9	negative selection	10072376
4248418	4248441	20	+	28162770	P31FUJ	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-0.3799558981980328	[164]	[148]	-3	hSpCas9	negative selection	10107694
4248040	4248063	20	+	28162770	P31FUJ	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.3101079305818275	[459]	[217]	-7	hSpCas9	negative selection	10107695
4248163	4248186	20	+	28162770	P31FUJ	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.5412440418041159	[337]	[577]	6	hSpCas9	negative selection	10107696
4248748	4248771	20	-	28162770	P31FUJ	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	1.8375871234770191	[19]	[83]	9	hSpCas9	negative selection	10107697
4248702	4248725	20	-	28162770	P31FUJ	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.12083475020032197	[53]	[68]	1	hSpCas9	negative selection	10107698
4248475	4248498	20	+	28162770	P31FUJ	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-1.5864391590290794	[137]	[53]	-7	hSpCas9	negative selection	10107699
4248378	4248401	20	+	28162770	P31FUJ	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-0.2260763412260652	[213]	[214]	-2	hSpCas9	negative selection	10107700
4248265	4248288	20	+	28162770	P31FUJ	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.34254761039772175	[313]	[290]	-3	hSpCas9	negative selection	10107701
4248087	4248110	20	-	28162770	P31FUJ	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	0.20920234246473468	[52]	[71]	2	hSpCas9	negative selection	10107702
4248051	4248074	20	-	28162770	P31FUJ	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	-0.14399293745652275	[62]	[66]	-1	hSpCas9	negative selection	10107703
4248418	4248441	20	+	28162770	TF1	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10277060
4248040	4248063	20	+	28162770	TF1	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10277061
4248163	4248186	20	+	28162770	TF1	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[226]	1	hSpCas9	negative selection	10277062
4248748	4248771	20	-	28162770	TF1	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10277063
4248702	4248725	20	-	28162770	TF1	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10277064
4248475	4248498	20	+	28162770	TF1	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[124]	1	hSpCas9	negative selection	10277065
4248378	4248401	20	+	28162770	TF1	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[208]	1	hSpCas9	negative selection	10277066
4248265	4248288	20	+	28162770	TF1	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[253]	1	hSpCas9	negative selection	10277067
4248087	4248110	20	-	28162770	TF1	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10277068
4248051	4248074	20	-	28162770	TF1	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10277069
4248418	4248441	20	+	28162770	SKM1	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-0.44543834655779724	[56]	[73]	-4	hSpCas9	negative selection	10446426
4248040	4248063	20	+	28162770	SKM1	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.4189368404092375	[120]	[79]	-7	hSpCas9	negative selection	10446427
4248163	4248186	20	+	28162770	SKM1	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.3409368731042002	[91]	[205]	3	hSpCas9	negative selection	10446428
4248748	4248771	20	-	28162770	SKM1	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	0.7629608026991506	[12]	[38]	7	hSpCas9	negative selection	10446429
4248702	4248725	20	-	28162770	SKM1	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.025995208532944458	[14]	[26]	0	hSpCas9	negative selection	10446430
4248475	4248498	20	+	28162770	SKM1	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-0.8821226904595765	[48]	[46]	-6	hSpCas9	negative selection	10446431
4248378	4248401	20	+	28162770	SKM1	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-0.14392979290936775	[39]	[63]	-1	hSpCas9	negative selection	10446432
4248265	4248288	20	+	28162770	SKM1	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.8571911264843055	[82]	[80]	-6	hSpCas9	negative selection	10446433
4248087	4248110	20	-	28162770	SKM1	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	0.9280200489696471	[10]	[36]	8	hSpCas9	negative selection	10446434
4248051	4248074	20	-	28162770	SKM1	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	1.7946696624264888	[14]	[91]	9	hSpCas9	negative selection	10446435
4248418	4248441	20	+	28162770	SKM1	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-0.44543834655779724	[56]	[73]	-4	hSpCas9	negative selection	10615792
4248040	4248063	20	+	28162770	SKM1	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.4189368404092375	[120]	[79]	-7	hSpCas9	negative selection	10615793
4248163	4248186	20	+	28162770	SKM1	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.3409368731042002	[91]	[205]	3	hSpCas9	negative selection	10615794
4248748	4248771	20	-	28162770	SKM1	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	0.7629608026991506	[12]	[38]	7	hSpCas9	negative selection	10615795
4248702	4248725	20	-	28162770	SKM1	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.025995208532944458	[14]	[26]	0	hSpCas9	negative selection	10615796
4248475	4248498	20	+	28162770	SKM1	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-0.8821226904595765	[48]	[46]	-6	hSpCas9	negative selection	10615797
4248378	4248401	20	+	28162770	SKM1	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-0.14392979290936775	[39]	[63]	-1	hSpCas9	negative selection	10615798
4248265	4248288	20	+	28162770	SKM1	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.8571911264843055	[82]	[80]	-6	hSpCas9	negative selection	10615799
4248087	4248110	20	-	28162770	SKM1	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	0.9280200489696471	[10]	[36]	8	hSpCas9	negative selection	10615800
4248051	4248074	20	-	28162770	SKM1	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	1.7946696624264888	[14]	[91]	9	hSpCas9	negative selection	10615801
4248418	4248441	20	+	28162770	PL21	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-1.9544374226195562	[186]	[20]	-8	hSpCas9	negative selection	10785158
4248040	4248063	20	+	28162770	PL21	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.058947606827811	[291]	[60]	-6	hSpCas9	negative selection	10785159
4248163	4248186	20	+	28162770	PL21	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.18296447068118804	[337]	[166]	1	hSpCas9	negative selection	10785160
4248748	4248771	20	-	28162770	PL21	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	-0.4843585597827502	[44]	[13]	-3	hSpCas9	negative selection	10785161
4248702	4248725	20	-	28162770	PL21	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	-0.092642134738526	[48]	[19]	0	hSpCas9	negative selection	10785162
4248475	4248498	20	+	28162770	PL21	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	0.1847095739197142	[187]	[92]	1	hSpCas9	negative selection	10785163
4248378	4248401	20	+	28162770	PL21	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	1.8770246046515155	[151]	[242]	9	hSpCas9	negative selection	10785164
4248265	4248288	20	+	28162770	PL21	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-1.461173772361951	[290]	[45]	-7	hSpCas9	negative selection	10785165
4248087	4248110	20	-	28162770	PL21	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	1.6015021768710875	[52]	[69]	9	hSpCas9	negative selection	10785166
4248051	4248074	20	-	28162770	PL21	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	1.8314950206949274	[50]	[78]	9	hSpCas9	negative selection	10785167
4248418	4248441	20	+	28162770	P31FUJ	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-0.3799558981980328	[164]	[148]	-3	hSpCas9	negative selection	10954524
4248040	4248063	20	+	28162770	P31FUJ	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.3101079305818275	[459]	[217]	-7	hSpCas9	negative selection	10954525
4248163	4248186	20	+	28162770	P31FUJ	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.5412440418041159	[337]	[577]	6	hSpCas9	negative selection	10954526
4248748	4248771	20	-	28162770	P31FUJ	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	1.8375871234770191	[19]	[83]	9	hSpCas9	negative selection	10954527
4248702	4248725	20	-	28162770	P31FUJ	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.12083475020032197	[53]	[68]	1	hSpCas9	negative selection	10954528
4248475	4248498	20	+	28162770	P31FUJ	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-1.5864391590290794	[137]	[53]	-7	hSpCas9	negative selection	10954529
4248378	4248401	20	+	28162770	P31FUJ	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-0.2260763412260652	[213]	[214]	-2	hSpCas9	negative selection	10954530
4248265	4248288	20	+	28162770	P31FUJ	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.34254761039772175	[313]	[290]	-3	hSpCas9	negative selection	10954531
4248087	4248110	20	-	28162770	P31FUJ	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	0.20920234246473468	[52]	[71]	2	hSpCas9	negative selection	10954532
4248051	4248074	20	-	28162770	P31FUJ	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	-0.14399293745652275	[62]	[66]	-1	hSpCas9	negative selection	10954533
4248418	4248441	20	+	28162770	OCIAML5	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-0.5011594090048688	[68]	[87]	-3	hSpCas9	negative selection	11123890
4248040	4248063	20	+	28162770	OCIAML5	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-0.5450412986256891	[252]	[312]	-4	hSpCas9	negative selection	11123891
4248163	4248186	20	+	28162770	OCIAML5	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.9361372508486954	[129]	[448]	7	hSpCas9	negative selection	11123892
4248748	4248771	20	-	28162770	OCIAML5	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	2.92052293303293	[2]	[40]	9	hSpCas9	negative selection	11123893
4248702	4248725	20	-	28162770	OCIAML5	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	2.0548240247445215	[7]	[59]	9	hSpCas9	negative selection	11123894
4248475	4248498	20	+	28162770	OCIAML5	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-0.4819549424666696	[105]	[136]	-3	hSpCas9	negative selection	11123895
4248378	4248401	20	+	28162770	OCIAML5	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	0.46986152402336534	[85]	[214]	4	hSpCas9	negative selection	11123896
4248265	4248288	20	+	28162770	OCIAML5	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.0941621726950223	[163]	[315]	0	hSpCas9	negative selection	11123897
4248087	4248110	20	-	28162770	OCIAML5	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	1.3939126707900666	[38]	[184]	9	hSpCas9	negative selection	11123898
4248051	4248074	20	-	28162770	OCIAML5	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	1.7724242940437966	[29]	[184]	9	hSpCas9	negative selection	11123899
4248418	4248441	20	+	28162770	EOL1	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	0.7512161686849728	[264]	[234]	6	hSpCas9	negative selection	11293256
4248040	4248063	20	+	28162770	EOL1	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-0.5141133322342083	[430]	[158]	-4	hSpCas9	negative selection	11293257
4248163	4248186	20	+	28162770	EOL1	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.8040250102044929	[548]	[504]	7	hSpCas9	negative selection	11293258
4248748	4248771	20	-	28162770	EOL1	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	1.7640830993772885	[37]	[67]	9	hSpCas9	negative selection	11293259
4248702	4248725	20	-	28162770	EOL1	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	-0.09383075774432026	[78]	[38]	0	hSpCas9	negative selection	11293260
4248475	4248498	20	+	28162770	EOL1	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-0.11498059261610283	[295]	[143]	-1	hSpCas9	negative selection	11293261
4248378	4248401	20	+	28162770	EOL1	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-0.03310593771987064	[234]	[120]	0	hSpCas9	negative selection	11293262
4248265	4248288	20	+	28162770	EOL1	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.2939507336614223	[369]	[158]	-2	hSpCas9	negative selection	11293263
4248087	4248110	20	-	28162770	EOL1	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	0.8360110969688773	[83]	[78]	7	hSpCas9	negative selection	11293264
4248051	4248074	20	-	28162770	EOL1	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	-0.008338032570928355	[83]	[43]	0	hSpCas9	negative selection	11293265
4248418	4248441	20	+	28162770	MOLM13	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-0.08054724315146325	[233]	[159]	0	hSpCas9	negative selection	11462622
4248040	4248063	20	+	28162770	MOLM13	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.8046364732665126	[487]	[100]	-7	hSpCas9	negative selection	11462623
4248163	4248186	20	+	28162770	MOLM13	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	1.1136059133448313	[433]	[678]	8	hSpCas9	negative selection	11462624
4248748	4248771	20	-	28162770	MOLM13	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	-0.058179430123008746	[35]	[24]	0	hSpCas9	negative selection	11462625
4248702	4248725	20	-	28162770	MOLM13	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	-1.7634361645618768	[107]	[22]	-7	hSpCas9	negative selection	11462626
4248475	4248498	20	+	28162770	MOLM13	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-1.3967587655605351	[243]	[66]	-6	hSpCas9	negative selection	11462627
4248378	4248401	20	+	28162770	MOLM13	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-0.7003821010452197	[217]	[96]	-4	hSpCas9	negative selection	11462628
4248265	4248288	20	+	28162770	MOLM13	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.7587030283211549	[343]	[146]	-4	hSpCas9	negative selection	11462629
4248087	4248110	20	-	28162770	MOLM13	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	-1.237367352894289	[74]	[22]	-6	hSpCas9	negative selection	11462630
4248051	4248074	20	-	28162770	MOLM13	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	0.07884709079867935	[54]	[41]	0	hSpCas9	negative selection	11462631
4248418	4248441	20	+	28162770	HEL	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-0.29313083057992734	[219]	[114]	-2	hSpCas9	negative selection	11631988
4248040	4248063	20	+	28162770	HEL	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.0417593422717137	[449]	[139]	-6	hSpCas9	negative selection	11631989
4248163	4248186	20	+	28162770	HEL	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.754921881834474	[370]	[400]	6	hSpCas9	negative selection	11631990
4248748	4248771	20	-	28162770	HEL	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	-0.009337864579336053	[32]	[20]	0	hSpCas9	negative selection	11631991
4248702	4248725	20	-	28162770	HEL	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.4783520140994746	[64]	[57]	4	hSpCas9	negative selection	11631992
4248475	4248498	20	+	28162770	HEL	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	0.29904011444177553	[216]	[170]	2	hSpCas9	negative selection	11631993
4248378	4248401	20	+	28162770	HEL	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-1.6074877975328166	[156]	[32]	-7	hSpCas9	negative selection	11631994
4248265	4248288	20	+	28162770	HEL	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-1.1985634219805847	[300]	[83]	-6	hSpCas9	negative selection	11631995
4248087	4248110	20	-	28162770	HEL	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	-1.4056241895610422	[90]	[21]	-7	hSpCas9	negative selection	11631996
4248051	4248074	20	-	28162770	HEL	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	-0.19376243571676355	[49]	[27]	-1	hSpCas9	negative selection	11631997
4248418	4248441	20	+	28162770	MV411	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-1.2838370790443927	[210]	[72]	-7	hSpCas9	negative selection	11801354
4248040	4248063	20	+	28162770	MV411	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-1.103059696301358	[305]	[119]	-6	hSpCas9	negative selection	11801355
4248163	4248186	20	+	28162770	MV411	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.6909190280757693	[338]	[460]	6	hSpCas9	negative selection	11801356
4248748	4248771	20	-	28162770	MV411	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	-0.38999236983251606	[27]	[17]	-3	hSpCas9	negative selection	11801357
4248702	4248725	20	-	28162770	MV411	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.5629393765107047	[44]	[55]	5	hSpCas9	negative selection	11801358
4248475	4248498	20	+	28162770	MV411	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-0.8510523126165882	[196]	[91]	-5	hSpCas9	negative selection	11801359
4248378	4248401	20	+	28162770	MV411	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-0.20673834240302674	[136]	[99]	-1	hSpCas9	negative selection	11801360
4248265	4248288	20	+	28162770	MV411	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-1.135643181724407	[252]	[96]	-6	hSpCas9	negative selection	11801361
4248087	4248110	20	-	28162770	MV411	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	0.3876152088310354	[48]	[53]	3	hSpCas9	negative selection	11801362
4248051	4248074	20	-	28162770	MV411	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	1.198527950301829	[29]	[57]	9	hSpCas9	negative selection	11801363
4248418	4248441	20	+	28162770	MONOMAC1	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	0.8613273154544349	[108]	[226]	7	hSpCas9	negative selection	11970720
4248040	4248063	20	+	28162770	MONOMAC1	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-0.6387422968004776	[181]	[133]	-5	hSpCas9	negative selection	11970721
4248163	4248186	20	+	28162770	MONOMAC1	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	-0.06792924443067527	[234]	[256]	0	hSpCas9	negative selection	11970722
4248748	4248771	20	-	28162770	MONOMAC1	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	3.0290312324202926	[13]	[130]	9	hSpCas9	negative selection	11970723
4248702	4248725	20	-	28162770	MONOMAC1	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.5156812008599754	[35]	[58]	5	hSpCas9	negative selection	11970724
4248475	4248498	20	+	28162770	MONOMAC1	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-1.589354269838314	[125]	[47]	-8	hSpCas9	negative selection	11970725
4248378	4248401	20	+	28162770	MONOMAC1	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	0.12164558832415445	[88]	[110]	1	hSpCas9	negative selection	11970726
4248265	4248288	20	+	28162770	MONOMAC1	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.48103505805308394	[164]	[263]	5	hSpCas9	negative selection	11970727
4248087	4248110	20	-	28162770	MONOMAC1	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	-0.08600553467080996	[24]	[26]	0	hSpCas9	negative selection	11970728
4248051	4248074	20	-	28162770	MONOMAC1	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	1.043971252444241	[21]	[51]	8	hSpCas9	negative selection	11970729
4248418	4248441	20	+	28162770	OCIAML2	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	0.12391872430819295	[24]	[150]	1	hSpCas9	negative selection	12140086
4248040	4248063	20	+	28162770	OCIAML2	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-0.9300614438794585	[54]	[159]	-6	hSpCas9	negative selection	12140087
4248163	4248186	20	+	28162770	OCIAML2	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	0.5226755221838305	[53]	[429]	5	hSpCas9	negative selection	12140088
4248748	4248771	20	-	28162770	OCIAML2	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	-0.07831240246340077	[7]	[41]	0	hSpCas9	negative selection	12140089
4248702	4248725	20	-	28162770	OCIAML2	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	0.47690275486370304	[6]	[53]	4	hSpCas9	negative selection	12140090
4248475	4248498	20	+	28162770	OCIAML2	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-0.620206181292671	[32]	[118]	-5	hSpCas9	negative selection	12140091
4248378	4248401	20	+	28162770	OCIAML2	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	-0.590924058959873	[24]	[91]	-4	hSpCas9	negative selection	12140092
4248265	4248288	20	+	28162770	OCIAML2	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	-0.7963999864239175	[46]	[149]	-5	hSpCas9	negative selection	12140093
4248087	4248110	20	-	28162770	OCIAML2	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	0.766409372058688	[6]	[65]	7	hSpCas9	negative selection	12140094
4248051	4248074	20	-	28162770	OCIAML2	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	0.30697775342139066	[13]	[95]	3	hSpCas9	negative selection	12140095
4248418	4248441	20	+	28162770	OCIAML3	viability	GCAGCACAGCACGTCCACGGCGG	ADRA1D	ENSG00000171873	-0.11019186305990677	[63]	[178]	-1	hSpCas9	negative selection	12309452
4248040	4248063	20	+	28162770	OCIAML3	viability	GATGCGCAGCACCACCTCGGAGG	ADRA1D	ENSG00000171873	-0.8946671184578743	[100]	[163]	-6	hSpCas9	negative selection	12309453
4248163	4248186	20	+	28162770	OCIAML3	viability	CAGGTAGAAGGAGCACACGGAGG	ADRA1D	ENSG00000171873	-0.2536675083229205	[108]	[275]	-2	hSpCas9	negative selection	12309454
4248748	4248771	20	-	28162770	OCIAML3	viability	AGGACAACCGGAGCTCCGCGGGG	ADRA1D	ENSG00000171873	1.4503864790342904	[11]	[98]	9	hSpCas9	negative selection	12309455
4248702	4248725	20	-	28162770	OCIAML3	viability	CGGCGACGTGAATGGCACGGCGG	ADRA1D	ENSG00000171873	1.323530199483864	[8]	[67]	9	hSpCas9	negative selection	12309456
4248475	4248498	20	+	28162770	OCIAML3	viability	GAAGCCCAGAACCTCCATGGTGG	ADRA1D	ENSG00000171873	-0.021117971903582056	[39]	[118]	0	hSpCas9	negative selection	12309457
4248378	4248401	20	+	28162770	OCIAML3	viability	GGTCCACGGAGATGGTGCAGAGG	ADRA1D	ENSG00000171873	0.4819412129091355	[36]	[155]	4	hSpCas9	negative selection	12309458
4248265	4248288	20	+	28162770	OCIAML3	viability	GGGCCCTACGGACACCACCAGGG	ADRA1D	ENSG00000171873	0.03339012671738967	[66]	[206]	0	hSpCas9	negative selection	12309459
4248087	4248110	20	-	28162770	OCIAML3	viability	CACCACGCGCAGCCTCGAGGCGG	ADRA1D	ENSG00000171873	1.4877864508394842	[14]	[126]	9	hSpCas9	negative selection	12309460
4248051	4248074	20	-	28162770	OCIAML3	viability	GCGAGGCAAGGCCTCCGAGGTGG	ADRA1D	ENSG00000171873	0.6174964648695488	[18]	[87]	5	hSpCas9	negative selection	12309461