Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:150
• Symbol:ADRA2A
• Description:adrenoceptor alpha 2A

DataSource: http://genomecrispr.dkfz.de/#!/results/ADRA2A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
111079340	111079363	10	-	26472758	Jiyoye	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	3.214530303563477	[0]	[6]	9	hSpCas9	negative selection	3449
111078480	111078503	10	-	26472758	Jiyoye	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	-0.7750279497148758	[235]	[103]	-5	hSpCas9	negative selection	3450
111078115	111078138	10	-	26472758	Jiyoye	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.20072450403844688	[179]	[155]	1	hSpCas9	negative selection	3451
111078329	111078352	10	+	26472758	Jiyoye	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.5155080032939469	[217]	[234]	4	hSpCas9	negative selection	3452
111078535	111078558	10	-	26472758	Jiyoye	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	2.6295678028423213	[11]	[55]	9	hSpCas9	negative selection	3453
111078558	111078581	10	+	26472758	Jiyoye	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	-0.2544084008181954	[86]	[54]	-2	hSpCas9	negative selection	3454
111079148	111079171	10	+	26472758	Jiyoye	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.1754450955900892	[154]	[131]	1	hSpCas9	negative selection	3455
111079234	111079257	10	-	26472758	Jiyoye	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	-0.5322830765590758	[139]	[72]	-4	hSpCas9	negative selection	3456
111077999	111078022	10	+	26472758	Jiyoye	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	-0.5152880180231062	[162]	[85]	-4	hSpCas9	negative selection	3457
111078160	111078183	10	-	26472758	Jiyoye	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	3458
111079340	111079363	10	-	26472758	KBM7	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	-0.47034121848502064	[26,20]	[15,0]	-4	hSpCas9	negative selection	194567
111078480	111078503	10	-	26472758	KBM7	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.6124120248907468	[779,647]	[597,432]	6	hSpCas9	negative selection	194568
111078115	111078138	10	-	26472758	KBM7	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.459120716860177	[575,264]	[246,276]	5	hSpCas9	negative selection	194569
111078329	111078352	10	+	26472758	KBM7	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.19313614948927205	[1133,686]	[497,462]	2	hSpCas9	negative selection	194570
111078535	111078558	10	-	26472758	KBM7	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	-0.17559434004979702	[227,275]	[116,96]	-2	hSpCas9	negative selection	194571
111078558	111078581	10	+	26472758	KBM7	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	0.762735811128143	[294,123]	[170,151]	8	hSpCas9	negative selection	194572
111079148	111079171	10	+	26472758	KBM7	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.11138409043993691	[739,630]	[298,389]	1	hSpCas9	negative selection	194573
111079234	111079257	10	-	26472758	KBM7	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.5535070274861503	[589,535]	[331,438]	6	hSpCas9	negative selection	194574
111077999	111078022	10	+	26472758	KBM7	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.257410247674922	[471,351]	[120,325]	2	hSpCas9	negative selection	194575
111078160	111078183	10	-	26472758	KBM7	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	-1.7169813575843147	[1,10]	[0,0]	-8	hSpCas9	negative selection	194576
111079340	111079363	10	-	26472758	Raji	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	0.859456021930014	[18]	[7]	7	hSpCas9	negative selection	385685
111078480	111078503	10	-	26472758	Raji	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.07214635531705793	[372]	[90]	0	hSpCas9	negative selection	385686
111078115	111078138	10	-	26472758	Raji	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.04848984632003088	[249]	[59]	0	hSpCas9	negative selection	385687
111078329	111078352	10	+	26472758	Raji	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	-0.06398488293838178	[499]	[110]	0	hSpCas9	negative selection	385688
111078535	111078558	10	-	26472758	Raji	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	0.4272638016121034	[140]	[43]	4	hSpCas9	negative selection	385689
111078558	111078581	10	+	26472758	Raji	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	-0.5930561827674925	[90]	[13]	-5	hSpCas9	negative selection	385690
111079148	111079171	10	+	26472758	Raji	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.2581149715826011	[226]	[62]	2	hSpCas9	negative selection	385691
111079234	111079257	10	-	26472758	Raji	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.38749145456633477	[223]	[67]	3	hSpCas9	negative selection	385692
111077999	111078022	10	+	26472758	Raji	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	-0.06949422671047997	[207]	[45]	0	hSpCas9	negative selection	385693
111078160	111078183	10	-	26472758	Raji	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	3.1073835353735992	[4]	[9]	9	hSpCas9	negative selection	385694
111079340	111079363	10	-	26472758	K562	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	1.8137843733365842	[30]	[91]	9	hSpCas9	negative selection	576803
111078480	111078503	10	-	26472758	K562	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.4978213711761835	[525]	[626]	4	hSpCas9	negative selection	576804
111078115	111078138	10	-	26472758	K562	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.8578478836896636	[367]	[562]	7	hSpCas9	negative selection	576805
111078329	111078352	10	+	26472758	K562	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.012073525903793403	[799]	[680]	0	hSpCas9	negative selection	576806
111078535	111078558	10	-	26472758	K562	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	-0.18150708775513313	[265]	[197]	-1	hSpCas9	negative selection	576807
111078558	111078581	10	+	26472758	K562	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	-1.2465676248456952	[207]	[73]	-6	hSpCas9	negative selection	576808
111079148	111079171	10	+	26472758	K562	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	-0.03187757757626955	[458]	[378]	0	hSpCas9	negative selection	576809
111079234	111079257	10	-	26472758	K562	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	-0.01861567816734705	[449]	[374]	0	hSpCas9	negative selection	576810
111077999	111078022	10	+	26472758	K562	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.3388110979414017	[280]	[299]	2	hSpCas9	negative selection	576811
111078160	111078183	10	-	26472758	K562	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	4.703850346303744	[0]	[21]	9	hSpCas9	negative selection	576812
111078181	111078204	10	-	26627737	DLD1	viability	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.4351519544146309	[882]	[261,179,173]	-4	hSpCas9	negative selection	773688
111078431	111078454	10	+	26627737	DLD1	viability	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.10996887342466755	[1666]	[532,479,655]	1	hSpCas9	negative selection	773689
111078597	111078620	10	-	26627737	DLD1	viability	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.09971239473000026	[1567]	[447,842,328]	1	hSpCas9	negative selection	773690
111078604	111078627	10	+	26627737	DLD1	viability	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.23719283684839332	[582]	[164,250,227]	2	hSpCas9	negative selection	773691
111079246	111079269	10	-	26627737	DLD1	viability	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	-0.07815061125501546	[575]	[153,225,138]	-1	hSpCas9	negative selection	773692
111079343	111079366	10	-	26627737	DLD1	viability	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.4241025013945307	[427]	[122,196,213]	4	hSpCas9	negative selection	773693
111078181	111078204	10	-	26627737	GBM cells	viability after 5 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.22116257710606538	[287]	[136,127]	-3	hSpCas9	negative selection	856003
111078431	111078454	10	+	26627737	GBM cells	viability after 5 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.3237799915326378	[767]	[512,517]	5	hSpCas9	negative selection	856004
111078597	111078620	10	-	26627737	GBM cells	viability after 5 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.489658728200848	[580]	[415,458]	7	hSpCas9	negative selection	856005
111078604	111078627	10	+	26627737	GBM cells	viability after 5 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.3508779431628867	[404]	[305,247]	5	hSpCas9	negative selection	856006
111079246	111079269	10	-	26627737	GBM cells	viability after 5 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.2114364635385951	[276]	[130,212]	3	hSpCas9	negative selection	856007
111079343	111079366	10	-	26627737	GBM cells	viability after 5 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.1717960666758267	[364]	[216,223]	2	hSpCas9	negative selection	856008
111078181	111078204	10	-	26627737	GBM cells	viability after 13 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	0.3014437201237542	[287]	[239,153]	4	hSpCas9	negative selection	938318
111078431	111078454	10	+	26627737	GBM cells	viability after 13 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.25131554588448624	[767]	[629,386]	3	hSpCas9	negative selection	938319
111078597	111078620	10	-	26627737	GBM cells	viability after 13 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.8018388721916863	[580]	[564,536]	8	hSpCas9	negative selection	938320
111078604	111078627	10	+	26627737	GBM cells	viability after 13 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.250627020377132	[404]	[304,225]	3	hSpCas9	negative selection	938321
111079246	111079269	10	-	26627737	GBM cells	viability after 13 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.14013760186718308	[276]	[174,157]	1	hSpCas9	negative selection	938322
111079343	111079366	10	-	26627737	GBM cells	viability after 13 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.02598641468952645	[364]	[242,167]	0	hSpCas9	negative selection	938323
111078181	111078204	10	-	26627737	GBM cells	viability after 21 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	0.5960724498144563	[287]	[247,225]	6	hSpCas9	negative selection	1020633
111078431	111078454	10	+	26627737	GBM cells	viability after 21 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.41881744629032425	[767]	[562,552]	4	hSpCas9	negative selection	1020634
111078597	111078620	10	-	26627737	GBM cells	viability after 21 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.5603729921553646	[580]	[524,410]	6	hSpCas9	negative selection	1020635
111078604	111078627	10	+	26627737	GBM cells	viability after 21 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.020935665185826013	[404]	[240,206]	0	hSpCas9	negative selection	1020636
111079246	111079269	10	-	26627737	GBM cells	viability after 21 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.14374987351011795	[276]	[171,160]	1	hSpCas9	negative selection	1020637
111079343	111079366	10	-	26627737	GBM cells	viability after 21 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.025739540225491964	[364]	[204,198]	0	hSpCas9	negative selection	1020638
111078181	111078204	10	-	26627737	RPE1	viability after 9 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.19741295312504825	[1206]	[260,417]	-1	hSpCas9	negative selection	1102948
111078431	111078454	10	+	26627737	RPE1	viability after 9 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.9347827429830917	[5140]	[572,1188]	-6	hSpCas9	negative selection	1102949
111078597	111078620	10	-	26627737	RPE1	viability after 9 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.9396289976323942	[1780]	[1168,940]	6	hSpCas9	negative selection	1102950
111078604	111078627	10	+	26627737	RPE1	viability after 9 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.5386786529022977	[2150]	[315,653]	-4	hSpCas9	negative selection	1102951
111079246	111079269	10	-	26627737	RPE1	viability after 9 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	1.6357005946003922	[466]	[390,535]	8	hSpCas9	negative selection	1102952
111079343	111079366	10	-	26627737	RPE1	viability after 9 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-0.2344342019998414	[783]	[181,242]	-2	hSpCas9	negative selection	1102953
111078181	111078204	10	-	26627737	RPE1	viability after 12 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	0.15601193814714576	[1206]	[405,313]	1	hSpCas9	negative selection	1185263
111078431	111078454	10	+	26627737	RPE1	viability after 12 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.9476182883524489	[5140]	[635,800]	-6	hSpCas9	negative selection	1185264
111078597	111078620	10	-	26627737	RPE1	viability after 12 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.8537193242241126	[1780]	[990,730]	5	hSpCas9	negative selection	1185265
111078604	111078627	10	+	26627737	RPE1	viability after 12 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.46063117847731205	[2150]	[366,475]	-3	hSpCas9	negative selection	1185266
111079246	111079269	10	-	26627737	RPE1	viability after 12 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	1.6452239790206433	[466]	[509,267]	8	hSpCas9	negative selection	1185267
111079343	111079366	10	-	26627737	RPE1	viability after 12 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.310412654216998	[783]	[284,235]	2	hSpCas9	negative selection	1185268
111078181	111078204	10	-	26627737	RPE1	viability after 15 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.062064740461935664	[1206]	[351,302]	0	hSpCas9	negative selection	1267578
111078431	111078454	10	+	26627737	RPE1	viability after 15 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-1.2612040346889535	[5140]	[256,943]	-7	hSpCas9	negative selection	1267579
111078597	111078620	10	-	26627737	RPE1	viability after 15 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	1.2432805234476245	[1780]	[1406,985]	7	hSpCas9	negative selection	1267580
111078604	111078627	10	+	26627737	RPE1	viability after 15 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.7320772859008708	[2150]	[291,437]	-4	hSpCas9	negative selection	1267581
111079246	111079269	10	-	26627737	RPE1	viability after 15 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	1.485939808628304	[466]	[424,316]	7	hSpCas9	negative selection	1267582
111079343	111079366	10	-	26627737	RPE1	viability after 15 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.3332295767235162	[783]	[284,273]	2	hSpCas9	negative selection	1267583
111078181	111078204	10	-	26627737	RPE1	viability after 18 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.38556403755094815	[1206]	[200,300]	-2	hSpCas9	negative selection	1349893
111078431	111078454	10	+	26627737	RPE1	viability after 18 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.9653442875164098	[5140]	[624,801]	-6	hSpCas9	negative selection	1349894
111078597	111078620	10	-	26627737	RPE1	viability after 18 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.8413279238860547	[1780]	[821,902]	5	hSpCas9	negative selection	1349895
111078604	111078627	10	+	26627737	RPE1	viability after 18 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.5860296094231675	[2150]	[348,426]	-4	hSpCas9	negative selection	1349896
111079246	111079269	10	-	26627737	RPE1	viability after 18 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	1.602018247072601	[466]	[486,270]	8	hSpCas9	negative selection	1349897
111079343	111079366	10	-	26627737	RPE1	viability after 18 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-0.05513219092254169	[783]	[236,167]	0	hSpCas9	negative selection	1349898
111078181	111078204	10	-	26627737	HeLa	viability after 8 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.42016854539493853	[520]	[190,92,224]	-4	hSpCas9	negative selection	1432208
111078431	111078454	10	+	26627737	HeLa	viability after 8 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.4616798924732046	[1046]	[746,703,468]	4	hSpCas9	negative selection	1432209
111078597	111078620	10	-	26627737	HeLa	viability after 8 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.25087246425928345	[1279]	[891,665,492]	2	hSpCas9	negative selection	1432210
111078604	111078627	10	+	26627737	HeLa	viability after 8 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.1873413476096818	[808]	[313,178,426]	-2	hSpCas9	negative selection	1432211
111079246	111079269	10	-	26627737	HeLa	viability after 8 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.4959164329264372	[282]	[273,138,132]	4	hSpCas9	negative selection	1432212
111079343	111079366	10	-	26627737	HeLa	viability after 8 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-1.963557569881825	[1029]	[186,108,67]	-9	hSpCas9	negative selection	1432213
111078181	111078204	10	-	26627737	HeLa	viability after 12 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-1.2183470633900528	[520]	[89,106,78]	-8	hSpCas9	negative selection	1514523
111078431	111078454	10	+	26627737	HeLa	viability after 12 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.7901200000023971	[1046]	[951,762,533]	6	hSpCas9	negative selection	1514524
111078597	111078620	10	-	26627737	HeLa	viability after 12 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.39793930935668453	[1279]	[825,703,563]	3	hSpCas9	negative selection	1514525
111078604	111078627	10	+	26627737	HeLa	viability after 12 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.12550032202938732	[808]	[349,246,329]	-1	hSpCas9	negative selection	1514526
111079246	111079269	10	-	26627737	HeLa	viability after 12 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.768392023954733	[282]	[266,138,199]	6	hSpCas9	negative selection	1514527
111079343	111079366	10	-	26627737	HeLa	viability after 12 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-0.98312685131361	[1029]	[96,248,292]	-7	hSpCas9	negative selection	1514528
111078181	111078204	10	-	26627737	HeLa	viability after 15 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.8639030456354502	[520]	[76,121,153]	-6	hSpCas9	negative selection	1596838
111078431	111078454	10	+	26627737	HeLa	viability after 15 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.8151091162325375	[1046]	[509,1027,711]	6	hSpCas9	negative selection	1596839
111078597	111078620	10	-	26627737	HeLa	viability after 15 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.5244530587518639	[1279]	[619,569,1085]	4	hSpCas9	negative selection	1596840
111078604	111078627	10	+	26627737	HeLa	viability after 15 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.4929700900221383	[808]	[466,380,548]	4	hSpCas9	negative selection	1596841
111079246	111079269	10	-	26627737	HeLa	viability after 15 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.2545743773961364	[282]	[165,95,150]	2	hSpCas9	negative selection	1596842
111079343	111079366	10	-	26627737	HeLa	viability after 15 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-0.7941406410845493	[1029]	[206,311,203]	-6	hSpCas9	negative selection	1596843
111078181	111078204	10	-	26627737	HeLa	viability after 18 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.8466943942977466	[520]	[51,103,153]	-6	hSpCas9	negative selection	1679153
111078431	111078454	10	+	26627737	HeLa	viability after 18 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.7918173349602284	[1046]	[346,815,711]	6	hSpCas9	negative selection	1679154
111078597	111078620	10	-	26627737	HeLa	viability after 18 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.5563761817384714	[1279]	[442,478,1085]	4	hSpCas9	negative selection	1679155
111078604	111078627	10	+	26627737	HeLa	viability after 18 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.4905291900933473	[808]	[308,318,548]	4	hSpCas9	negative selection	1679156
111079246	111079269	10	-	26627737	HeLa	viability after 18 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.20866857476270134	[282]	[104,76,150]	1	hSpCas9	negative selection	1679157
111079343	111079366	10	-	26627737	HeLa	viability after 18 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-0.7600874396041131	[1029]	[147,260,203]	-6	hSpCas9	negative selection	1679158
111078181	111078204	10	-	26627737	HCT116	viability after 6 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	0.49410651055226323	[430]	[175,50]	2	hSpCas9	negative selection	1761468
111078431	111078454	10	+	26627737	HCT116	viability after 6 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.36048319196026357	[1798]	[734,157]	2	hSpCas9	negative selection	1761469
111078597	111078620	10	-	26627737	HCT116	viability after 6 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.3669727451569207	[2039]	[731,237]	2	hSpCas9	negative selection	1761470
111078604	111078627	10	+	26627737	HCT116	viability after 6 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-1.4083656879309472	[1054]	[95,43]	-7	hSpCas9	negative selection	1761471
111079246	111079269	10	-	26627737	HCT116	viability after 6 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.43093907917442087	[1009]	[574,14]	2	hSpCas9	negative selection	1761472
111079343	111079366	10	-	26627737	HCT116	viability after 6 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-1.4012880891708854	[945]	[103,29]	-7	hSpCas9	negative selection	1761473
111078181	111078204	10	-	26627737	HCT116	viability after 8 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.26197424469956093	[392]	[188,177,174]	-3	hSpCas9	negative selection	1843783
111078431	111078454	10	+	26627737	HCT116	viability after 8 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.05943891719906391	[1135]	[607,656,537]	0	hSpCas9	negative selection	1843784
111078597	111078620	10	-	26627737	HCT116	viability after 8 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.09955005522266913	[832]	[394,449,626]	1	hSpCas9	negative selection	1843785
111078604	111078627	10	+	26627737	HCT116	viability after 8 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.448127581931936	[539]	[456,376,384]	5	hSpCas9	negative selection	1843786
111079246	111079269	10	-	26627737	HCT116	viability after 8 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.16942681341107657	[460]	[257,350,247]	2	hSpCas9	negative selection	1843787
111079343	111079366	10	-	26627737	HCT116	viability after 8 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.859624420395267	[266]	[294,288,217]	7	hSpCas9	negative selection	1843788
111078181	111078204	10	-	26627737	HCT116	viability after 9 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	1.0639061720876901	[430]	[191,278]	7	hSpCas9	negative selection	1926098
111078431	111078454	10	+	26627737	HCT116	viability after 9 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.7029686537668893	[1798]	[891,694]	5	hSpCas9	negative selection	1926099
111078597	111078620	10	-	26627737	HCT116	viability after 9 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.669384786733271	[2039]	[662,1026]	5	hSpCas9	negative selection	1926100
111078604	111078627	10	+	26627737	HCT116	viability after 9 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.17847850069885096	[1054]	[334,305]	1	hSpCas9	negative selection	1926101
111079246	111079269	10	-	26627737	HCT116	viability after 9 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	-0.260675554740259	[1009]	[80,338]	-2	hSpCas9	negative selection	1926102
111079343	111079366	10	-	26627737	HCT116	viability after 9 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-1.1265401449722972	[945]	[213,37]	-7	hSpCas9	negative selection	1926103
111078181	111078204	10	-	26627737	HCT116	viability after 12 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	0.29772917431413065	[392]	[313,198,241]	3	hSpCas9	negative selection	2008413
111078431	111078454	10	+	26627737	HCT116	viability after 12 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.12849751586232072	[1135]	[747,560,311]	-1	hSpCas9	negative selection	2008414
111078597	111078620	10	-	26627737	HCT116	viability after 12 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.3256667109473439	[832]	[473,695,485]	3	hSpCas9	negative selection	2008415
111078604	111078627	10	+	26627737	HCT116	viability after 12 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.28402956170372484	[539]	[422,353,252]	3	hSpCas9	negative selection	2008416
111079246	111079269	10	-	26627737	HCT116	viability after 12 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.34257671149164814	[460]	[363,281,269]	3	hSpCas9	negative selection	2008417
111079343	111079366	10	-	26627737	HCT116	viability after 12 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.3953391652680337	[266]	[86,257,218]	4	hSpCas9	negative selection	2008418
111078181	111078204	10	-	26627737	HCT116	viability after 15 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	0.3305436554309003	[392]	[305,169,376]	3	hSpCas9	negative selection	2090728
111078431	111078454	10	+	26627737	HCT116	viability after 15 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.2364243811207163	[1135]	[571,738,354]	-2	hSpCas9	negative selection	2090729
111078597	111078620	10	-	26627737	HCT116	viability after 15 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	-0.12997130373832233	[832]	[450,407,453]	-1	hSpCas9	negative selection	2090730
111078604	111078627	10	+	26627737	HCT116	viability after 15 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.4722202506094283	[539]	[566,452,288]	4	hSpCas9	negative selection	2090731
111079246	111079269	10	-	26627737	HCT116	viability after 15 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.2967961267333582	[460]	[309,353,309]	3	hSpCas9	negative selection	2090732
111079343	111079366	10	-	26627737	HCT116	viability after 15 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.41675896062297135	[266]	[168,174,264]	4	hSpCas9	negative selection	2090733
111078181	111078204	10	-	26627737	HCT116	viability after 18 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	0.6476686211949676	[392]	[360,219,317]	5	hSpCas9	negative selection	2173043
111078431	111078454	10	+	26627737	HCT116	viability after 18 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.3791976951545919	[1135]	[405,409,452]	-3	hSpCas9	negative selection	2173044
111078597	111078620	10	-	26627737	HCT116	viability after 18 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.28023854163381645	[832]	[389,573,497]	2	hSpCas9	negative selection	2173045
111078604	111078627	10	+	26627737	HCT116	viability after 18 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.3968623934461918	[539]	[442,432,139]	3	hSpCas9	negative selection	2173046
111079246	111079269	10	-	26627737	HCT116	viability after 18 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.6312296962589801	[460]	[372,338,322]	5	hSpCas9	negative selection	2173047
111079343	111079366	10	-	26627737	HCT116	viability after 18 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.15437713683739565	[266]	[97,127,208]	1	hSpCas9	negative selection	2173048
111078550	111078573	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATCTCCATCGAGAAGAAGGGCGG	ADRA2A	ENSG00000150594	0.19163262093857805	[3,3]	[4,3]	4	hSpCas9	positive selection	2969205
111078480	111078503	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.24768741043691075	[2,1]	[1,2]	5	hSpCas9	positive selection	2969206
111078550	111078573	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATCTCCATCGAGAAGAAGGGCGG	ADRA2A	ENSG00000150594	0.21480077191364563	[3,3]	[4,1]	4	hSpCas9	positive selection	3037063
111078480	111078503	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	-0.08130815956515991	[2,2]	[2,0]	-1	hSpCas9	positive selection	3037064
111079219	111079242		-	24336571	A375	resistance to PLX after 7 days	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	-0.09804099746855616	[8,8]	[8,7]	-3	hSpCas9	positive selection	3107280
111078893	111078916		+	24336571	A375	resistance to PLX after 7 days	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	-0.18773273015381367	[14,10]	[8,12]	-6	hSpCas9	positive selection	3107285
111079219	111079242		-	24336571	A375	resistance to PLX after 14 days	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.4296022566244506	[9,9]	[4,7]	4	hSpCas9	positive selection	3165073
111078893	111078916		+	24336571	A375	resistance to PLX after 14 days	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	-1.0962509968142369	[13,15]	[2,1]	-9	hSpCas9	positive selection	3165078
111079219	111079242		-	24336571	A375	viability after 7 days	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.4285706203534437	[6]	[8,8]	6	hSpCas9	negative selection	3222866
111078893	111078916		+	24336571	A375	viability after 7 days	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.477313679377835	[8]	[14,10]	7	hSpCas9	negative selection	3222871
111079219	111079242		-	24336571	A375	viability after 14 days	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.6320937762822469	[6]	[9,9]	7	hSpCas9	negative selection	3280659
111078893	111078916		+	24336571	A375	viability after 14 days	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.6889100465634987	[8]	[13,15]	8	hSpCas9	negative selection	3280664
111078893	111078916	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	-0.009399098213644026	[152,154]	[0,0]	0	hSpCas9	positive selection	3335785
111079219	111079242	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.6655044535692226	[89,102]	[0,0]	3	hSpCas9	positive selection	3335786
111078627	111078650	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.7048704520000199	[306,190]	[0,0]	-5	hSpCas9	positive selection	3335787
111078058	111078081	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	2.257326211445835	[31,31]	[0,0]	8	hSpCas9	positive selection	3355034
111078709	111078732	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.04787284581688529	[147,147]	[0,0]	0	hSpCas9	positive selection	3355035
111079331	111079354	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	0.9905396707509337	[76,76]	[0,0]	4	hSpCas9	positive selection	3355036
111078549	111078572	10	+	26780180	HT29	viability (Avana library 4 designs)	ATCTCCATCGAGAAGAAGGGCGG	ADRA2A	ENSG00000150594	-0.172167913161553	[]	[]	-3	hSpCas9	negative selection	3405269
111078480	111078503	10	-	26780180	HT29	viability (Avana library 4 designs)	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	1.59001519838581	[]	[]	6	hSpCas9	negative selection	3405270
111078508	111078531	10	-	26780180	HT29	viability (Avana library 4 designs)	GACGGCCGAGATGACCCACACGG	ADRA2A	ENSG00000150594	0.986008549522003	[]	[]	4	hSpCas9	negative selection	3405271
111078079	111078102	10	+	26780180	HT29	viability (Avana library 4 designs)	GGAACGGGACCGAGGCGCCGGGG	ADRA2A	ENSG00000150594	-0.213163724019162	[]	[]	-3	hSpCas9	negative selection	3405272
111078508	111078531	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACGGCCGAGATGACCCACACGG	ADRA2A	ENSG00000150594	6.27831655779552	[]	[]	9	hSpCas9	negative selection	3477198
111078079	111078102	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAACGGGACCGAGGCGCCGGGG	ADRA2A	ENSG00000150594	2.2606175251522	[]	[]	3	hSpCas9	negative selection	3477199
111078549	111078572	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATCTCCATCGAGAAGAAGGGCGG	ADRA2A	ENSG00000150594	-2.28762380722649	[]	[]	-3	hSpCas9	negative selection	3477200
111078480	111078503	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	5.05090096794666	[]	[]	8	hSpCas9	negative selection	3477201
111078508	111078531	10	-	26780180	A375	viability (Avana lentiGuide)	GACGGCCGAGATGACCCACACGG	ADRA2A	ENSG00000150594	7.70325112508465	[]	[]	6	hSpCas9	negative selection	3585857
111078079	111078102	10	+	26780180	A375	viability (Avana lentiGuide)	GGAACGGGACCGAGGCGCCGGGG	ADRA2A	ENSG00000150594	-0.456651106093656	[]	[]	0	hSpCas9	negative selection	3585858
111078549	111078572	10	+	26780180	A375	viability (Avana lentiGuide)	ATCTCCATCGAGAAGAAGGGCGG	ADRA2A	ENSG00000150594	5.63947929783384	[]	[]	5	hSpCas9	negative selection	3585859
111078480	111078503	10	-	26780180	A375	viability (Avana lentiGuide)	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	-2.94820071960073	[]	[]	-5	hSpCas9	negative selection	3585860
111078508	111078531	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACGGCCGAGATGACCCACACGG	ADRA2A	ENSG00000150594	0.3811694206548543	[4]	[6,5]	9	hSpCas9	positive selection	3694516
111078079	111078102	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAACGGGACCGAGGCGCCGGGG	ADRA2A	ENSG00000150594	0.1126919194912222	[3]	[4,3]	3	hSpCas9	positive selection	3694517
111078549	111078572	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCTCCATCGAGAAGAAGGGCGG	ADRA2A	ENSG00000150594	-0.12902012519199724	[5]	[4,4]	-2	hSpCas9	positive selection	3694518
111078480	111078503	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.22972385030774792	[4]	[5,4]	6	hSpCas9	positive selection	3694519
111078508	111078531	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACGGCCGAGATGACCCACACGG	ADRA2A	ENSG00000150594	0.11785424909413757	[5]	[5,4]	2	hSpCas9	positive selection	3803123
111078079	111078102	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAACGGGACCGAGGCGCCGGGG	ADRA2A	ENSG00000150594	-1.3558981116046698	[4]	[0,1]	-9	hSpCas9	positive selection	3803124
111078549	111078572	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCTCCATCGAGAAGAAGGGCGG	ADRA2A	ENSG00000150594	-0.5106885051233362	[5]	[4,1]	-6	hSpCas9	positive selection	3803125
111078480	111078503	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.1865890263626825	[4]	[4,3]	4	hSpCas9	positive selection	3803126
111079219	111079242	10	-	26780180	A375	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.325297957321204	[]	[]	0	hSpCas9	negative selection	3911586
111078058	111078081	10	+	26780180	A375	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.589347688472145	[]	[]	1	hSpCas9	negative selection	3911587
111078893	111078916	10	+	26780180	A375	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.849699447571789	[]	[]	3	hSpCas9	negative selection	3911588
111078627	111078650	10	+	26780180	A375	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	1.05340626251294	[]	[]	5	hSpCas9	negative selection	3911589
111079331	111079354	10	-	26780180	A375	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	1.13767842392625	[]	[]	6	hSpCas9	negative selection	3911590
111078709	111078732	10	-	26780180	A375	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.819690341297508	[]	[]	3	hSpCas9	negative selection	3911591
111079219	111079242	10	-	26780180	HT29	viability (GeCKOv2 library)	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.809592200508777	[]	[]	3	hSpCas9	negative selection	4019552
111078058	111078081	10	+	26780180	HT29	viability (GeCKOv2 library)	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	1.30234665561669	[]	[]	6	hSpCas9	negative selection	4019553
111078893	111078916	10	+	26780180	HT29	viability (GeCKOv2 library)	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.421460390379499	[]	[]	1	hSpCas9	negative selection	4019554
111078627	111078650	10	+	26780180	HT29	viability (GeCKOv2 library)	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	0.545306320993549	[]	[]	1	hSpCas9	negative selection	4019555
111079331	111079354	10	-	26780180	HT29	viability (GeCKOv2 library)	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	1.26652766190267	[]	[]	6	hSpCas9	negative selection	4019556
111078709	111078732	10	-	26780180	HT29	viability (GeCKOv2 library)	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.757029664208044	[]	[]	3	hSpCas9	negative selection	4019557
111079219	111079242	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.18407380695030562	[3]	[1,2]	5	hSpCas9	positive selection	4129524
111078893	111078916	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	-0.45617044429310577	[3]	[1,1]	-8	hSpCas9	positive selection	4129535
111079219	111079242	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	1.091524096945361	[2]	[0,0,1,3]	7	hSpCas9	positive selection	4193546
111078893	111078916	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.5302844586456457	[3]	[0,4,4,0]	3	hSpCas9	positive selection	4193557
111078893	111078916	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	-0.04899227273735976	[2]	[2,1]	-1	hSpCas9	positive selection	4254749
111079219	111079242	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.49989624378602004	[2]	[3,3]	9	hSpCas9	positive selection	4254750
111078627	111078650	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.1681757084753734	[3]	[4,1]	-3	hSpCas9	positive selection	4254751
111078058	111078081	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.22685485488490953	[1]	[1,0]	-4	hSpCas9	positive selection	4319031
111078709	111078732	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.017068503623178022	[2]	[2,1]	0	hSpCas9	positive selection	4319032
111079331	111079354	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.0510035976944192	[1]	[1,0]	-1	hSpCas9	positive selection	4319033
111078211	111078233	10	-	27760321	OCIAML3	viability	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	-0.4012937781381899	[326,280]	[162,200]	-4	hSpCas9	negative selection	4376521
111078335	111078357	10	+	27760321	OCIAML3	viability	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.49030281171555357	[587,509]	[519,707]	6	hSpCas9	negative selection	4376522
111078351	111078373	10	+	27760321	OCIAML3	viability	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.6799413177420857	[541,486]	[603,695]	7	hSpCas9	negative selection	4376523
111078432	111078454	10	+	27760321	OCIAML3	viability	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.2738771745142704	[664,499]	[484,625]	3	hSpCas9	negative selection	4376524
111078597	111078619	10	-	27760321	OCIAML3	viability	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	-0.31652780587459106	[1060,951]	[613,653]	-3	hSpCas9	negative selection	4376525
111078211	111078233	10	-	27760321	OCIAML2	viability	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	-0.3088811050305619	[326,280]	[184,214]	-4	hSpCas9	negative selection	4459984
111078335	111078357	10	+	27760321	OCIAML2	viability	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.41986152001237365	[587,509]	[479,740]	6	hSpCas9	negative selection	4459985
111078351	111078373	10	+	27760321	OCIAML2	viability	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.2715702773779479	[541,486]	[396,639]	3	hSpCas9	negative selection	4459986
111078432	111078454	10	+	27760321	OCIAML2	viability	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.2549463462060133	[664,499]	[366,423]	-3	hSpCas9	negative selection	4459987
111078597	111078619	10	-	27760321	OCIAML2	viability	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.21041161590040125	[1060,951]	[902,990]	2	hSpCas9	negative selection	4459988
111078211	111078233	10	-	27760321	MV411	viability	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	0.12966253523490773	[326,280]	[16,521]	0	hSpCas9	negative selection	4543447
111078335	111078357	10	+	27760321	MV411	viability	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	1.5387122678824874	[587,509]	[911,1256]	9	hSpCas9	negative selection	4543448
111078351	111078373	10	+	27760321	MV411	viability	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.7594804065760529	[541,486]	[249,1060]	5	hSpCas9	negative selection	4543449
111078432	111078454	10	+	27760321	MV411	viability	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.17758238990789477	[664,499]	[88,944]	1	hSpCas9	negative selection	4543450
111078597	111078619	10	-	27760321	MV411	viability	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.6451172756847732	[1060,951]	[1156,857]	5	hSpCas9	negative selection	4543451
111078211	111078233	10	-	27760321	HL60	viability	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	-1.0048683885265095	[326,280]	[102,144]	-7	hSpCas9	negative selection	4626910
111078335	111078357	10	+	27760321	HL60	viability	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.7410098480235345	[587,509]	[867,619]	8	hSpCas9	negative selection	4626911
111078351	111078373	10	+	27760321	HL60	viability	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.0835743158020367	[541,486]	[522,361]	1	hSpCas9	negative selection	4626912
111078432	111078454	10	+	27760321	HL60	viability	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.2753389716499634	[664,499]	[418,358]	-3	hSpCas9	negative selection	4626913
111078597	111078619	10	-	27760321	HL60	viability	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	-0.17239410676299705	[1060,951]	[719,737]	-2	hSpCas9	negative selection	4626914
111078211	111078233	10	-	27760321	HT1080	viability	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	-0.4309711034844528	[280,218]	[49,99]	-2	hSpCas9	negative selection	4710373
111078335	111078357	10	+	27760321	HT1080	viability	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.7307320138620634	[509,397]	[186,423]	4	hSpCas9	negative selection	4710374
111078351	111078373	10	+	27760321	HT1080	viability	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	1.2190507256549903	[486,379]	[317,493]	6	hSpCas9	negative selection	4710375
111078432	111078454	10	+	27760321	HT1080	viability	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	1.0300683516589377	[499,389]	[477,234]	5	hSpCas9	negative selection	4710376
111078597	111078619	10	-	27760321	HT1080	viability	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	1.7262826239561122	[951,742]	[1097,1137]	8	hSpCas9	negative selection	4710377
111078211	111078233	10	-	27760321	HT29	viability after 7 days	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	-0.7980968337836505	[280,218]	[214,172,170]	-8	hSpCas9	negative selection	4793836
111078335	111078357	10	+	27760321	HT29	viability after 7 days	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.06512803892881547	[509,397]	[614,582,632]	1	hSpCas9	negative selection	4793837
111078351	111078373	10	+	27760321	HT29	viability after 7 days	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	-0.11887824051973381	[486,379]	[543,694,310]	-2	hSpCas9	negative selection	4793838
111078432	111078454	10	+	27760321	HT29	viability after 7 days	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	-0.33772322912537234	[499,389]	[546,309,511]	-5	hSpCas9	negative selection	4793839
111078597	111078619	10	-	27760321	HT29	viability after 7 days	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.10110194132755068	[951,742]	[1349,1126,1056]	1	hSpCas9	negative selection	4793840
111078211	111078233	10	-	27760321	HT29	viability after 25 days	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	-0.09118361294601873	[280,218]	[242,274,289]	-1	hSpCas9	negative selection	4877299
111078335	111078357	10	+	27760321	HT29	viability after 25 days	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.4120392908107284	[509,397]	[560,672,861]	4	hSpCas9	negative selection	4877300
111078351	111078373	10	+	27760321	HT29	viability after 25 days	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.4681270509014427	[486,379]	[645,909,479]	5	hSpCas9	negative selection	4877301
111078432	111078454	10	+	27760321	HT29	viability after 25 days	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.4389918558978923	[499,389]	[822,345,912]	5	hSpCas9	negative selection	4877302
111078597	111078619	10	-	27760321	HT29	viability after 25 days	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.41271373859562055	[951,742]	[1191,1184,1518]	4	hSpCas9	negative selection	4877303
111078211	111078233	10	-	27760321	HT29	viability after 22 days	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	0.023432049539734212	[280,218]	[227,352,301]	0	hSpCas9	negative selection	4960762
111078335	111078357	10	+	27760321	HT29	viability after 22 days	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.5130570277557218	[509,397]	[541,807,903]	5	hSpCas9	negative selection	4960763
111078351	111078373	10	+	27760321	HT29	viability after 22 days	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.4395235219905629	[486,379]	[688,731,616]	5	hSpCas9	negative selection	4960764
111078432	111078454	10	+	27760321	HT29	viability after 22 days	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.22024512445610894	[499,389]	[459,589,752]	2	hSpCas9	negative selection	4960765
111078597	111078619	10	-	27760321	HT29	viability after 22 days	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.33137246823148314	[951,742]	[1233,1347,1114]	3	hSpCas9	negative selection	4960766
111078211	111078233	10	-	27760321	HT29	viability after 19 days	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	-0.30149508167009176	[280,218]	[342,228,138]	-3	hSpCas9	negative selection	5044225
111078335	111078357	10	+	27760321	HT29	viability after 19 days	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.5477120304344119	[509,397]	[807,859,618]	5	hSpCas9	negative selection	5044226
111078351	111078373	10	+	27760321	HT29	viability after 19 days	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.26851310548432383	[486,379]	[720,910,187]	2	hSpCas9	negative selection	5044227
111078432	111078454	10	+	27760321	HT29	viability after 19 days	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.31456837444223623	[499,389]	[882,234,799]	3	hSpCas9	negative selection	5044228
111078597	111078619	10	-	27760321	HT29	viability after 19 days	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.5625894084484568	[951,742]	[1855,1263,1225]	5	hSpCas9	negative selection	5044229
111078211	111078233	10	-	27760321	HT29	viability after 16 days	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	0.08935998461452083	[280,218]	[310,368,211]	0	hSpCas9	negative selection	5127688
111078335	111078357	10	+	27760321	HT29	viability after 16 days	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.5680300075688522	[509,397]	[538,817,879]	6	hSpCas9	negative selection	5127689
111078351	111078373	10	+	27760321	HT29	viability after 16 days	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.26596923444804854	[486,379]	[728,514,520]	3	hSpCas9	negative selection	5127690
111078432	111078454	10	+	27760321	HT29	viability after 16 days	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.5011251694748131	[499,389]	[711,452,955]	6	hSpCas9	negative selection	5127691
111078597	111078619	10	-	27760321	HT29	viability after 16 days	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.3151754887438756	[951,742]	[1203,995,1345]	3	hSpCas9	negative selection	5127692
111078211	111078233	10	-	27760321	HT29	viability after 13 days	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	-0.4586171525451942	[280,218]	[131,183,310]	-5	hSpCas9	negative selection	5211151
111078335	111078357	10	+	27760321	HT29	viability after 13 days	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	0.5050806656741509	[509,397]	[533,930,775]	6	hSpCas9	negative selection	5211152
111078351	111078373	10	+	27760321	HT29	viability after 13 days	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	-0.061773204829776135	[486,379]	[210,718,513]	0	hSpCas9	negative selection	5211153
111078432	111078454	10	+	27760321	HT29	viability after 13 days	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.21594248568364222	[499,389]	[484,664,645]	2	hSpCas9	negative selection	5211154
111078597	111078619	10	-	27760321	HT29	viability after 13 days	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.20690391915693818	[951,742]	[1671,937,812]	2	hSpCas9	negative selection	5211155
111078211	111078233	10	-	27760321	HT29	viability after 10 days	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	-0.5189251004933082	[280,218]	[195,178,275]	-6	hSpCas9	negative selection	5294614
111078335	111078357	10	+	27760321	HT29	viability after 10 days	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	-0.027879014219594045	[509,397]	[503,781,391]	0	hSpCas9	negative selection	5294615
111078351	111078373	10	+	27760321	HT29	viability after 10 days	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.35199769375647516	[486,379]	[490,573,996]	5	hSpCas9	negative selection	5294616
111078432	111078454	10	+	27760321	HT29	viability after 10 days	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.14320638612488967	[499,389]	[395,718,725]	1	hSpCas9	negative selection	5294617
111078597	111078619	10	-	27760321	HT29	viability after 10 days	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.3536234051689229	[951,742]	[1671,1068,1307]	5	hSpCas9	negative selection	5294618
111078211	111078233	10	-	27760321	MOLM13	viability	AGCGCGCGGCTCGTGAACACGG	ADRA2A	ENSG00000150594	0.21243117605629724	[326,280]	[54,319]	1	hSpCas9	negative selection	5378077
111078335	111078357	10	+	27760321	MOLM13	viability	CTGGTACTTCGGCAAGGCTTGG	ADRA2A	ENSG00000150594	1.253109531610338	[587,509]	[582,866]	8	hSpCas9	negative selection	5378078
111078351	111078373	10	+	27760321	MOLM13	viability	GCTTGGTGCGAGATCTACCTGG	ADRA2A	ENSG00000150594	0.6390115435336751	[541,486]	[450,451]	4	hSpCas9	negative selection	5378079
111078432	111078454	10	+	27760321	MOLM13	viability	CGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	1.2056596896459042	[664,499]	[1125,432]	8	hSpCas9	negative selection	5378080
111078597	111078619	10	-	27760321	MOLM13	viability	GGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	1.0703419073144391	[1060,951]	[1505,922]	7	hSpCas9	negative selection	5378081
111077422	111077445	10	+	27661255	K562	viability	GCCAGAACCGCAGCGTCTGGGGG	ADRA2A	ENSG00000150594	0.037867828335486964	[439,568]	[427,397]	1	dCas9-KRAB	negative selection	5461186
111077459	111077482	10	+	27661255	K562	viability	GTAATCGCTTCGGGGATGTAAGG	ADRA2A	ENSG00000150594	0.13034223854347937	[2167,2549]	[2319,1831]	4	dCas9-KRAB	negative selection	5461187
111077472	111077495	10	+	27661255	K562	viability	GGATGTAAGGCGACAGACATAGG	ADRA2A	ENSG00000150594	0.20254735005502222	[1309,1593]	[1316,1340]	7	dCas9-KRAB	negative selection	5461188
111078893	111078916	10	+	27260156	BXPC3	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.49759222596706043	[354]	[506,577,524,474]	9	hSpCas9	negative selection	5527209
111079219	111079242	10	-	27260156	BXPC3	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.04256035308908125	[453]	[421,553,478,501]	0	hSpCas9	negative selection	5527210
111078627	111078650	10	+	27260156	BXPC3	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.3702473411821622	[977]	[788,671,902,805]	-7	hSpCas9	negative selection	5527211
111078058	111078081	10	+	27260156	BXPC3	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.015954782669909573	[78]	[113,56,81,77]	0	hSpCas9	negative selection	5591491
111078709	111078732	10	-	27260156	BXPC3	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.016183493420924677	[351]	[366,358,371,353]	0	hSpCas9	negative selection	5591492
111079331	111079354	10	-	27260156	BXPC3	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.025282343331083146	[141]	[99,127,140,229]	0	hSpCas9	negative selection	5591493
111078893	111078916	10	+	27260156	A673	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.31423718391728084	[354]	[571,425,478,656]	7	hSpCas9	negative selection	5648460
111079219	111079242	10	-	27260156	A673	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.14444989446441545	[453]	[726,540,559,596]	3	hSpCas9	negative selection	5648461
111078627	111078650	10	+	27260156	A673	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.1650092389362242	[977]	[1110,1059,934,1091]	-4	hSpCas9	negative selection	5648462
111078058	111078081	10	+	27260156	A673	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.0555318472360149	[78]	[51,34,153,121]	-1	hSpCas9	negative selection	5712742
111078709	111078732	10	-	27260156	A673	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.06331622401033032	[351]	[513,465,324,470]	1	hSpCas9	negative selection	5712743
111079331	111079354	10	-	27260156	A673	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.08071131600690373	[141]	[205,153,146,141]	-2	hSpCas9	negative selection	5712744
111078893	111078916	10	+	27260156	A375	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.709194995095247	[354]	[482,882,682,685]	9	hSpCas9	negative selection	5769711
111079219	111079242	10	-	27260156	A375	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.28897664710436316	[453]	[621,707,645,623]	4	hSpCas9	negative selection	5769712
111078627	111078650	10	+	27260156	A375	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.23191693253062506	[977]	[742,1109,918,1114]	-3	hSpCas9	negative selection	5769713
111078058	111078081	10	+	27260156	A375	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.060474423592954185	[78]	[125,78,90,59]	-1	hSpCas9	negative selection	5833993
111078709	111078732	10	-	27260156	A375	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.003626479023756568	[351]	[400,409,410,415]	0	hSpCas9	negative selection	5833994
111079331	111079354	10	-	27260156	A375	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.28501684582594033	[141]	[119,237,146,61]	-4	hSpCas9	negative selection	5833995
111078893	111078916	10	+	27260156	COLO741	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.5499972710326856	[354]	[605,785,598]	9	hSpCas9	negative selection	5890962
111079219	111079242	10	-	27260156	COLO741	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.37104094173400765	[453]	[910,750,610]	7	hSpCas9	negative selection	5890963
111078627	111078650	10	+	27260156	COLO741	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.17011114977192188	[977]	[1280,1126,947]	-4	hSpCas9	negative selection	5890964
111078058	111078081	10	+	27260156	COLO741	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.30960326236517366	[78]	[94,78,71]	-6	hSpCas9	negative selection	5955244
111078709	111078732	10	-	27260156	COLO741	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.03110457390205662	[351]	[575,361,449]	0	hSpCas9	negative selection	5955245
111079331	111079354	10	-	27260156	COLO741	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.2763864544820305	[141]	[145,225,81]	-5	hSpCas9	negative selection	5955246
111078893	111078916	10	+	27260156	CAL120	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.4852413709448078	[354]	[711,651,506]	7	hSpCas9	negative selection	6012213
111079219	111079242	10	-	27260156	CAL120	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.5169997108411217	[453]	[528,1049,803]	7	hSpCas9	negative selection	6012214
111078627	111078650	10	+	27260156	CAL120	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.2046718566402368	[977]	[1053,923,1186]	-3	hSpCas9	negative selection	6012215
111078058	111078081	10	+	27260156	CAL120	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.5006197689317156	[78]	[66,12,126]	-6	hSpCas9	negative selection	6076495
111078709	111078732	10	-	27260156	CAL120	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.1317814362604358	[351]	[368,692,362]	2	hSpCas9	negative selection	6076496
111079331	111079354	10	-	27260156	CAL120	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.6100874438281985	[141]	[69,77,190]	-7	hSpCas9	negative selection	6076497
111078893	111078916	10	+	27260156	CADOES1	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.3262742376377015	[354]	[453,435,371,392]	5	hSpCas9	negative selection	6133464
111079219	111079242	10	-	27260156	CADOES1	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	-0.16789463068068186	[453]	[299,452,394,354]	-3	hSpCas9	negative selection	6133465
111078627	111078650	10	+	27260156	CADOES1	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.816216409563626	[977]	[565,431,475,594]	-8	hSpCas9	negative selection	6133466
111078058	111078081	10	+	27260156	CADOES1	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.08491274629158418	[78]	[113,34,81,44]	-1	hSpCas9	negative selection	6197746
111078709	111078732	10	-	27260156	CADOES1	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.01371086385055681	[351]	[345,291,334,323]	0	hSpCas9	negative selection	6197747
111079331	111079354	10	-	27260156	CADOES1	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	0.012367382904590718	[141]	[63,218,146,101]	0	hSpCas9	negative selection	6197748
111078893	111078916	10	+	27260156	EWS502	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.40872920263313267	[354]	[485,525,370,618]	7	hSpCas9	negative selection	6254715
111079219	111079242	10	-	27260156	EWS502	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.4019680068861095	[453]	[598,472,764,720]	7	hSpCas9	negative selection	6254716
111078627	111078650	10	+	27260156	EWS502	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.16640738037159997	[977]	[915,920,873,981]	-3	hSpCas9	negative selection	6254717
111078058	111078081	10	+	27260156	EWS502	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.1411409279228919	[78]	[28,128,99,46]	-3	hSpCas9	negative selection	6318997
111078709	111078732	10	-	27260156	EWS502	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.2289242981130094	[351]	[377,419,440,520]	4	hSpCas9	negative selection	6318998
111079331	111079354	10	-	27260156	EWS502	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.30337100837945763	[141]	[107,121,119,139]	-5	hSpCas9	negative selection	6318999
111078893	111078916	10	+	27260156	EW8	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.24335207731189232	[354]	[351,345,343,319]	4	hSpCas9	negative selection	6375966
111079219	111079242	10	-	27260156	EW8	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.22416413468897345	[453]	[501,562,315,364]	4	hSpCas9	negative selection	6375967
111078627	111078650	10	+	27260156	EW8	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.2853455318733803	[977]	[525,732,710,605]	-5	hSpCas9	negative selection	6375968
111078058	111078081	10	+	27260156	EW8	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.05641636946578776	[78]	[38,86,65,50]	-1	hSpCas9	negative selection	6440248
111078709	111078732	10	-	27260156	EW8	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.2534282308510005	[351]	[375,305,381,291]	4	hSpCas9	negative selection	6440249
111079331	111079354	10	-	27260156	EW8	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.092398543825019	[141]	[65,146,125,84]	-2	hSpCas9	negative selection	6440250
111078893	111078916	10	+	27260156	CORL105	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.5164218734803869	[354]	[799,394,652,549]	8	hSpCas9	negative selection	6497217
111079219	111079242	10	-	27260156	CORL105	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.216336374274145	[453]	[711,541,626,594]	4	hSpCas9	negative selection	6497218
111078627	111078650	10	+	27260156	CORL105	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.16073616675041402	[977]	[991,965,1191,972]	-3	hSpCas9	negative selection	6497219
111078058	111078081	10	+	27260156	CORL105	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.21820734653330875	[78]	[102,88,154,90]	4	hSpCas9	negative selection	6561499
111078709	111078732	10	-	27260156	CORL105	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.2192465027292903	[351]	[268,398,404,346]	-4	hSpCas9	negative selection	6561500
111079331	111079354	10	-	27260156	CORL105	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	0.01585220612131044	[141]	[153,149,161,204]	0	hSpCas9	negative selection	6561501
111078893	111078916	10	+	27260156	HS294T	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.7680684040165427	[354]	[220,180,202,351]	8	hSpCas9	negative selection	6618468
111079219	111079242	10	-	27260156	HS294T	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.546602386105336	[453]	[172,448,198,194]	7	hSpCas9	negative selection	6618469
111078627	111078650	10	+	27260156	HS294T	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	0.4315159713570813	[977]	[276,759,581,417]	6	hSpCas9	negative selection	6618470
111078058	111078081	10	+	27260156	HS294T	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.32635917949837134	[78]	[36,56,32,22]	4	hSpCas9	negative selection	6682750
111078709	111078732	10	-	27260156	HS294T	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.3775889438207526	[351]	[214,127,197,160]	5	hSpCas9	negative selection	6682751
111079331	111079354	10	-	27260156	HS294T	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.1354335504008468	[141]	[40,34,80,42]	-2	hSpCas9	negative selection	6682752
111078893	111078916	10	+	27260156	HCC44	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.7929009353018326	[354]	[602,487,947,798]	9	hSpCas9	negative selection	6739719
111079219	111079242	10	-	27260156	HCC44	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.2409936769070268	[453]	[496,453,845,675]	4	hSpCas9	negative selection	6739720
111078627	111078650	10	+	27260156	HCC44	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	0.054834406069574904	[977]	[1018,1069,1608,972]	0	hSpCas9	negative selection	6739721
111078058	111078081	10	+	27260156	HCC44	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.2917770229584824	[78]	[87,45,132,40]	-5	hSpCas9	negative selection	6804001
111078709	111078732	10	-	27260156	HCC44	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.3817860394925685	[351]	[592,228,802,541]	6	hSpCas9	negative selection	6804002
111079331	111079354	10	-	27260156	HCC44	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.753973965459706	[141]	[97,28,177,98]	-8	hSpCas9	negative selection	6804003
111078893	111078916	10	+	27260156	G402	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.3431977073385365	[354]	[626,583,467,530]	4	hSpCas9	negative selection	6860970
111079219	111079242	10	-	27260156	G402	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.5338345669415357	[453]	[710,810,881,788]	6	hSpCas9	negative selection	6860971
111078627	111078650	10	+	27260156	G402	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.2553152888388427	[977]	[1882,740,593,894]	-3	hSpCas9	negative selection	6860972
111078058	111078081	10	+	27260156	G402	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-1.023778280839613	[78]	[11,17,112,39]	-8	hSpCas9	negative selection	6925252
111078709	111078732	10	-	27260156	G402	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.23144100839383436	[351]	[429,334,540,172]	-3	hSpCas9	negative selection	6925253
111079331	111079354	10	-	27260156	G402	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.7164856936749129	[141]	[68,254,62,40]	-7	hSpCas9	negative selection	6925254
111078893	111078916	10	+	27260156	L33	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.5896636555851025	[354]	[341,269,276,697]	9	hSpCas9	negative selection	6982221
111079219	111079242	10	-	27260156	L33	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.10034013261990465	[453]	[563,165,317,469]	2	hSpCas9	negative selection	6982222
111078627	111078650	10	+	27260156	L33	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.07139741143071832	[977]	[868,374,589,1000]	-2	hSpCas9	negative selection	6982223
111078058	111078081	10	+	27260156	L33	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.39862502087569496	[78]	[147,42,79,35]	7	hSpCas9	negative selection	7046503
111078709	111078732	10	-	27260156	L33	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.03081856667686894	[351]	[522,165,161,248]	0	hSpCas9	negative selection	7046504
111079331	111079354	10	-	27260156	L33	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.3890865726284256	[141]	[109,45,71,96]	-7	hSpCas9	negative selection	7046505
111078893	111078916	10	+	27260156	K562	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.8714754804723126	[354]	[480,528,708,573]	9	hSpCas9	negative selection	7103472
111079219	111079242	10	-	27260156	K562	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.29398260299534124	[453]	[482,553,501,442]	3	hSpCas9	negative selection	7103473
111078627	111078650	10	+	27260156	K562	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	0.14551114310312085	[977]	[1234,851,807,957]	1	hSpCas9	negative selection	7103474
111078058	111078081	10	+	27260156	K562	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.00880973552371156	[78]	[92,98,86,12]	0	hSpCas9	negative selection	7167754
111078709	111078732	10	-	27260156	K562	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.0637120350328384	[351]	[265,205,284,513]	0	hSpCas9	negative selection	7167755
111079331	111079354	10	-	27260156	K562	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.3812899877585514	[141]	[145,57,138,50]	-5	hSpCas9	negative selection	7167756
111078893	111078916	10	+	27260156	HT29	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.4874860730977688	[354]	[880,680,550,360]	8	hSpCas9	negative selection	7224723
111079219	111079242	10	-	27260156	HT29	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.13265843146284653	[453]	[545,661,664,549]	2	hSpCas9	negative selection	7224724
111078627	111078650	10	+	27260156	HT29	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.05533525907178327	[977]	[1048,1338,1129,1068]	-1	hSpCas9	negative selection	7224725
111078058	111078081	10	+	27260156	HT29	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.6941036502478428	[78]	[41,56,63,70]	-8	hSpCas9	negative selection	7289005
111078709	111078732	10	-	27260156	HT29	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.24109122197475957	[351]	[388,443,235,382]	-5	hSpCas9	negative selection	7289006
111079331	111079354	10	-	27260156	HT29	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.5740710713218118	[141]	[98,65,208,86]	-7	hSpCas9	negative selection	7289007
111078893	111078916	10	+	27260156	MHHES1	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.4046029484601787	[354]	[680,654,379,439]	7	hSpCas9	negative selection	7345974
111079219	111079242	10	-	27260156	MHHES1	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.11703750817847003	[453]	[753,560,537,410]	2	hSpCas9	negative selection	7345975
111078627	111078650	10	+	27260156	MHHES1	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.19469519271431912	[977]	[1045,1311,766,787]	-4	hSpCas9	negative selection	7345976
111078058	111078081	10	+	27260156	MHHES1	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.47758861198895053	[78]	[218,173,19,100]	8	hSpCas9	negative selection	7410256
111078709	111078732	10	-	27260156	MHHES1	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.02213688381416945	[351]	[453,347,454,355]	0	hSpCas9	negative selection	7410257
111079331	111079354	10	-	27260156	MHHES1	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	0.044511282935634666	[141]	[216,202,72,170]	0	hSpCas9	negative selection	7410258
111078893	111078916	10	+	27260156	MEWO	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.3472804634941383	[354]	[445,422,402]	7	hSpCas9	negative selection	7467225
111079219	111079242	10	-	27260156	MEWO	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.1537015220781347	[453]	[660,451,340]	3	hSpCas9	negative selection	7467226
111078627	111078650	10	+	27260156	MEWO	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	0.024104271476708794	[977]	[1226,815,805]	0	hSpCas9	negative selection	7467227
111078058	111078081	10	+	27260156	MEWO	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.46827835805491436	[78]	[114,142,50]	8	hSpCas9	negative selection	7531507
111078709	111078732	10	-	27260156	MEWO	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.0735422035154818	[351]	[420,254,283]	-2	hSpCas9	negative selection	7531508
111079331	111079354	10	-	27260156	MEWO	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.006894357790323102	[141]	[70,82,230]	0	hSpCas9	negative selection	7531509
111078893	111078916	10	+	27260156	LNCAPCLONEFGC	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.6529256735347334	[354]	[444,464,639,495]	9	hSpCas9	negative selection	7588476
111079219	111079242	10	-	27260156	LNCAPCLONEFGC	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	-0.10092617557179301	[453]	[350,217,617,392]	-2	hSpCas9	negative selection	7588477
111078627	111078650	10	+	27260156	LNCAPCLONEFGC	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.538429705177834	[977]	[566,505,648,730]	-7	hSpCas9	negative selection	7588478
111078058	111078081	10	+	27260156	LNCAPCLONEFGC	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.0920052712774635	[78]	[63,102,58,38]	-1	hSpCas9	negative selection	7652758
111078709	111078732	10	-	27260156	LNCAPCLONEFGC	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.09200627558738356	[351]	[236,383,244,317]	-1	hSpCas9	negative selection	7652759
111079331	111079354	10	-	27260156	LNCAPCLONEFGC	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.3229074525829134	[141]	[77,98,122,114]	-5	hSpCas9	negative selection	7652760
111078893	111078916	10	+	27260156	PANC0327	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.3783090935741948	[354]	[590,179,439,472]	5	hSpCas9	negative selection	7709727
111079219	111079242	10	-	27260156	PANC0327	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.8243399563099834	[453]	[460,1251,579,472]	9	hSpCas9	negative selection	7709728
111078627	111078650	10	+	27260156	PANC0327	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.22568120127829006	[977]	[831,542,896,732]	-3	hSpCas9	negative selection	7709729
111078058	111078081	10	+	27260156	PANC0327	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.4853259190117507	[78]	[67,49,51,31]	-6	hSpCas9	negative selection	7774009
111078709	111078732	10	-	27260156	PANC0327	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.030300440613396595	[351]	[294,302,248,376]	0	hSpCas9	negative selection	7774010
111079331	111079354	10	-	27260156	PANC0327	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.48704757339842186	[141]	[107,55,166,34]	-6	hSpCas9	negative selection	7774011
111078893	111078916	10	+	27260156	NCIH2009	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.7967138832309684	[354]	[1234,704,719]	9	hSpCas9	negative selection	7830978
111079219	111079242	10	-	27260156	NCIH2009	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.38958534140944223	[453]	[1005,833,685]	5	hSpCas9	negative selection	7830979
111078627	111078650	10	+	27260156	NCIH2009	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.17460532499661163	[977]	[1104,1212,1290]	-2	hSpCas9	negative selection	7830980
111078058	111078081	10	+	27260156	NCIH2009	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.17626707932920604	[78]	[92,161,111]	2	hSpCas9	negative selection	7895260
111078709	111078732	10	-	27260156	NCIH2009	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.17418919648816733	[351]	[1068,356,342]	2	hSpCas9	negative selection	7895261
111079331	111079354	10	-	27260156	NCIH2009	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.08861350227532006	[141]	[200,90,271]	-1	hSpCas9	negative selection	7895262
111078893	111078916	10	+	27260156	NCIH1373	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.8253029409762127	[354]	[924,850,396,174]	8	hSpCas9	negative selection	7952229
111079219	111079242	10	-	27260156	NCIH1373	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.8839083041593807	[453]	[957,667,1197,250]	8	hSpCas9	negative selection	7952230
111078627	111078650	10	+	27260156	NCIH1373	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.2829626739309494	[977]	[944,435,1027,332]	-3	hSpCas9	negative selection	7952231
111078058	111078081	10	+	27260156	NCIH1373	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.14731285876924627	[78]	[104,69,82,36]	1	hSpCas9	negative selection	8016511
111078709	111078732	10	-	27260156	NCIH1373	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.18648816046308608	[351]	[293,357,281,117]	-2	hSpCas9	negative selection	8016512
111079331	111079354	10	-	27260156	NCIH1373	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-1.270916793580872	[141]	[133,36,48,14]	-8	hSpCas9	negative selection	8016513
111078893	111078916	10	+	27260156	PATU8902	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.2823664375321976	[354]	[484,955,267,804]	3	hSpCas9	negative selection	8073480
111079219	111079242	10	-	27260156	PATU8902	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.06570392132965952	[453]	[637,636,324,1192]	0	hSpCas9	negative selection	8073481
111078627	111078650	10	+	27260156	PATU8902	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.521890765184897	[977]	[1297,1247,610,681]	-5	hSpCas9	negative selection	8073482
111078058	111078081	10	+	27260156	PATU8902	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.24919813281907022	[78]	[91,115,187,108]	2	hSpCas9	negative selection	8137762
111078709	111078732	10	-	27260156	PATU8902	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.3398885487041355	[351]	[354,565,122,596]	-3	hSpCas9	negative selection	8137763
111079331	111079354	10	-	27260156	PATU8902	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.35103288107913433	[141]	[168,94,290,10]	-4	hSpCas9	negative selection	8137764
111078893	111078916	10	+	27260156	PANC1	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.12468283526812662	[354]	[266,570,311,239]	2	hSpCas9	negative selection	8194731
111079219	111079242	10	-	27260156	PANC1	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.19103744852403948	[453]	[417,451,451,451]	3	hSpCas9	negative selection	8194732
111078627	111078650	10	+	27260156	PANC1	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.5308019161909118	[977]	[652,817,554,371]	-7	hSpCas9	negative selection	8194733
111078058	111078081	10	+	27260156	PANC1	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.027585096729600966	[78]	[58,73,29,106]	0	hSpCas9	negative selection	8259013
111078709	111078732	10	-	27260156	PANC1	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.31784158921991085	[351]	[212,483,424,400]	5	hSpCas9	negative selection	8259014
111079331	111079354	10	-	27260156	PANC1	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	0.33620039358886133	[141]	[238,201,122,70]	5	hSpCas9	negative selection	8259015
111078893	111078916	10	+	27260156	PANC0813	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.40615455765198644	[354]	[627,595,390,597]	6	hSpCas9	negative selection	8315982
111079219	111079242	10	-	27260156	PANC0813	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.3759955354179602	[453]	[655,603,770,730]	6	hSpCas9	negative selection	8315983
111078627	111078650	10	+	27260156	PANC0813	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	0.09766686609609088	[977]	[957,1355,1442,1138]	1	hSpCas9	negative selection	8315984
111078058	111078081	10	+	27260156	PANC0813	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.1057171009694593	[78]	[56,92,50,137]	-2	hSpCas9	negative selection	8380264
111078709	111078732	10	-	27260156	PANC0813	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.11221688622764475	[351]	[386,643,412,342]	1	hSpCas9	negative selection	8380265
111079331	111079354	10	-	27260156	PANC0813	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.2096285474846986	[141]	[176,142,121,137]	-3	hSpCas9	negative selection	8380266
111078893	111078916	10	+	27260156	RDES	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.6270523692182224	[354]	[554,609,616,756]	8	hSpCas9	negative selection	8437233
111079219	111079242	10	-	27260156	RDES	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.07329854791419055	[453]	[455,471,711,578]	1	hSpCas9	negative selection	8437234
111078627	111078650	10	+	27260156	RDES	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.5639282380189115	[977]	[594,561,1001,956]	-7	hSpCas9	negative selection	8437235
111078058	111078081	10	+	27260156	RDES	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.1595341484529249	[78]	[90,126,99,80]	2	hSpCas9	negative selection	8501515
111078709	111078732	10	-	27260156	RDES	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.21941886207077071	[351]	[293,273,439,402]	-4	hSpCas9	negative selection	8501516
111079331	111079354	10	-	27260156	RDES	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.31511718597856775	[141]	[111,126,107,185]	-5	hSpCas9	negative selection	8501517
111078893	111078916	10	+	27260156	PC3	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.34368918334135623	[354]	[276,202,794,715]	7	hSpCas9	negative selection	8558484
111079219	111079242	10	-	27260156	PC3	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.10263666548821757	[453]	[369,394,720,551]	2	hSpCas9	negative selection	8558485
111078627	111078650	10	+	27260156	PC3	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.1978256898775691	[977]	[465,982,1281,925]	-4	hSpCas9	negative selection	8558486
111078058	111078081	10	+	27260156	PC3	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-1.177068534094583	[78]	[20,50,34,33]	-9	hSpCas9	negative selection	8622766
111078709	111078732	10	-	27260156	PC3	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.24767317810987338	[351]	[319,259,1089,255]	5	hSpCas9	negative selection	8622767
111079331	111079354	10	-	27260156	PC3	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.5925695581362247	[141]	[98,74,133,65]	-8	hSpCas9	negative selection	8622768
111078893	111078916	10	+	27260156	PATU8988T	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.1824474157537756	[354]	[447,283,441,370]	3	hSpCas9	negative selection	8679735
111079219	111079242	10	-	27260156	PATU8988T	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.1399561971057731	[453]	[689,522,258,466]	2	hSpCas9	negative selection	8679736
111078627	111078650	10	+	27260156	PATU8988T	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	0.054655758441956026	[977]	[998,1187,750,1012]	0	hSpCas9	negative selection	8679737
111078058	111078081	10	+	27260156	PATU8988T	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.8596887840499623	[78]	[44,192,255,56]	9	hSpCas9	negative selection	8744017
111078709	111078732	10	-	27260156	PATU8988T	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.2908301009766983	[351]	[151,258,412,284]	-5	hSpCas9	negative selection	8744018
111079331	111079354	10	-	27260156	PATU8988T	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.23655142232647508	[141]	[79,45,86,257]	-4	hSpCas9	negative selection	8744019
111078893	111078916	10	+	27260156	T47D	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.5841638051935187	[354]	[605,620,682,566]	9	hSpCas9	negative selection	8800986
111079219	111079242	10	-	27260156	T47D	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.1752801423534099	[453]	[614,496,749,530]	4	hSpCas9	negative selection	8800987
111078627	111078650	10	+	27260156	T47D	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.2587891920375741	[977]	[947,868,973,1026]	-5	hSpCas9	negative selection	8800988
111078058	111078081	10	+	27260156	T47D	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.0012946931999842093	[78]	[91,100,84,88]	0	hSpCas9	negative selection	8865268
111078709	111078732	10	-	27260156	T47D	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.06891918140906661	[351]	[409,342,329,488]	-1	hSpCas9	negative selection	8865269
111079331	111079354	10	-	27260156	T47D	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.0001437197127431844	[141]	[134,116,254,156]	0	hSpCas9	negative selection	8865270
111078893	111078916	10	+	27260156	SU8686	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.7517423682581995	[354]	[584,599,462,737]	9	hSpCas9	negative selection	8922237
111079219	111079242	10	-	27260156	SU8686	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.341362084271352	[453]	[492,680,493,606]	6	hSpCas9	negative selection	8922238
111078627	111078650	10	+	27260156	SU8686	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.11063906129900447	[977]	[863,831,875,1049]	-2	hSpCas9	negative selection	8922239
111078058	111078081	10	+	27260156	SU8686	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.08973211925001046	[78]	[55,103,41,91]	-1	hSpCas9	negative selection	8986519
111078709	111078732	10	-	27260156	SU8686	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.28578426329350726	[351]	[435,356,433,489]	5	hSpCas9	negative selection	8986520
111079331	111079354	10	-	27260156	SU8686	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	0.34860059430938795	[141]	[112,116,285,225]	6	hSpCas9	negative selection	8986521
111078893	111078916	10	+	27260156	SKES1	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.48008258742082105	[354]	[445,577,430,516]	8	hSpCas9	negative selection	9043488
111079219	111079242	10	-	27260156	SKES1	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.09739952079631023	[453]	[569,575,463,360]	2	hSpCas9	negative selection	9043489
111078627	111078650	10	+	27260156	SKES1	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.3012934945530813	[977]	[823,925,835,613]	-6	hSpCas9	negative selection	9043490
111078058	111078081	10	+	27260156	SKES1	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.24080154227053496	[78]	[57,86,71,51]	-5	hSpCas9	negative selection	9107770
111078709	111078732	10	-	27260156	SKES1	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.202675236693583	[351]	[428,437,376,378]	4	hSpCas9	negative selection	9107771
111079331	111079354	10	-	27260156	SKES1	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.21978753886480007	[141]	[123,63,157,130]	-5	hSpCas9	negative selection	9107772
111078893	111078916	10	+	27260156	TOV112D	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.5090694259900422	[354]	[595,597,448,412]	8	hSpCas9	negative selection	9164739
111079219	111079242	10	-	27260156	TOV112D	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.03750755091876273	[453]	[631,390,253,580]	0	hSpCas9	negative selection	9164740
111078627	111078650	10	+	27260156	TOV112D	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.07141848571383136	[977]	[892,1157,848,880]	-1	hSpCas9	negative selection	9164741
111078058	111078081	10	+	27260156	TOV112D	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.1973458251705016	[78]	[29,106,112,32]	-4	hSpCas9	negative selection	9229021
111078709	111078732	10	-	27260156	TOV112D	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	0.14140183701947745	[351]	[451,640,316,216]	2	hSpCas9	negative selection	9229022
111079331	111079354	10	-	27260156	TOV112D	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.6652447807309925	[141]	[81,112,90,77]	-8	hSpCas9	negative selection	9229023
111078893	111078916	10	+	27260156	TC71	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.30363297246393695	[354]	[505,457,401,516]	7	hSpCas9	negative selection	9285990
111079219	111079242	10	-	27260156	TC71	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.33162789746371946	[453]	[687,490,630,638]	7	hSpCas9	negative selection	9285991
111078627	111078650	10	+	27260156	TC71	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.26136563560293014	[977]	[882,890,920,796]	-6	hSpCas9	negative selection	9285992
111078058	111078081	10	+	27260156	TC71	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	-0.4169670043403433	[78]	[119,29,31,71]	-8	hSpCas9	negative selection	9350272
111078709	111078732	10	-	27260156	TC71	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.11120732687014628	[351]	[316,365,379,332]	-3	hSpCas9	negative selection	9350273
111079331	111079354	10	-	27260156	TC71	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	-0.2468958546602118	[141]	[151,110,158,86]	-6	hSpCas9	negative selection	9350274
111078893	111078916	10	+	27260156	TC32	viability	GCCGCGCGACACCGACGCGCTGG	ADRA2A	ENSG00000150594	0.363734371269281	[354]	[387,294,639,463]	6	hSpCas9	negative selection	9407241
111079219	111079242	10	-	27260156	TC32	viability	CCCGACGGCCGTGAGCGTGTAGG	ADRA2A	ENSG00000150594	0.2612239211362475	[453]	[666,297,707,431]	4	hSpCas9	negative selection	9407242
111078627	111078650	10	+	27260156	TC32	viability	TACGTCATCTCGTCGTGCATCGG	ADRA2A	ENSG00000150594	-0.39587217105553263	[977]	[661,488,1016,725]	-6	hSpCas9	negative selection	9407243
111078058	111078081	10	+	27260156	TC32	viability	CGGACGCGGGCAACGCGAGCTGG	ADRA2A	ENSG00000150594	0.14566524027130123	[78]	[76,79,115,55]	2	hSpCas9	negative selection	9471523
111078709	111078732	10	-	27260156	TC32	viability	TGGCACGCGGGTGCGACGCTTGG	ADRA2A	ENSG00000150594	-0.4534453122007041	[351]	[202,168,372,263]	-7	hSpCas9	negative selection	9471524
111079331	111079354	10	-	27260156	TC32	viability	TGAAGGCGCGGCGGAAATCGTGG	ADRA2A	ENSG00000150594	0.1648453423717655	[141]	[78,172,180,161]	3	hSpCas9	negative selection	9471525
111078181	111078204	10	-	27869803	HPAFII	viability after 27 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	1.5221994268150565	[184]	[418,162,NaN]	9	hSpCas9	negative selection	9536676
111078431	111078454	10	+	27869803	HPAFII	viability after 27 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.6739894892514948	[669]	[549,571,NaN]	5	hSpCas9	negative selection	9536677
111078597	111078620	10	-	27869803	HPAFII	viability after 27 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.20040413407570612	[858]	[537,502,NaN]	1	hSpCas9	negative selection	9536678
111078604	111078627	10	+	27869803	HPAFII	viability after 27 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-1.0791760076193844	[680]	[223,123,NaN]	-6	hSpCas9	negative selection	9536679
111079246	111079269	10	-	27869803	HPAFII	viability after 27 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.4720497710783099	[276]	[333,91,NaN]	4	hSpCas9	negative selection	9536680
111079343	111079366	10	-	27869803	HPAFII	viability after 27 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.5470428829952612	[297]	[265,197,NaN]	4	hSpCas9	negative selection	9536681
111078181	111078204	10	-	27869803	HPAFII	viability after 15 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	1.140024779960917	[184]	[579,349,NaN]	9	hSpCas9	negative selection	9619125
111078431	111078454	10	+	27869803	HPAFII	viability after 15 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.6213985806603921	[669]	[1243,1022,NaN]	7	hSpCas9	negative selection	9619126
111078597	111078620	10	-	27869803	HPAFII	viability after 15 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	-0.14173067817238816	[858]	[1125,656,NaN]	-2	hSpCas9	negative selection	9619127
111078604	111078627	10	+	27869803	HPAFII	viability after 15 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.5707240693048152	[680]	[842,274,NaN]	-6	hSpCas9	negative selection	9619128
111079246	111079269	10	-	27869803	HPAFII	viability after 15 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.06702387550170427	[276]	[383,266,NaN]	0	hSpCas9	negative selection	9619129
111079343	111079366	10	-	27869803	HPAFII	viability after 15 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-0.01857178121436215	[297]	[383,273,NaN]	0	hSpCas9	negative selection	9619130
111078181	111078204	10	-	27869803	ASPC1	viability after 36 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	-0.4083602616771206	[677]	[73,323,133]	-4	hSpCas9	negative selection	9701574
111078431	111078454	10	+	27869803	ASPC1	viability after 36 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.13842362624239724	[1823]	[1164,556,481]	1	hSpCas9	negative selection	9701575
111078597	111078620	10	-	27869803	ASPC1	viability after 36 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	-0.09098986796840092	[1576]	[1022,355,283]	-1	hSpCas9	negative selection	9701576
111078604	111078627	10	+	27869803	ASPC1	viability after 36 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	0.5026757561131678	[1232]	[543,733,550]	5	hSpCas9	negative selection	9701577
111079246	111079269	10	-	27869803	ASPC1	viability after 36 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	-0.18978546824849182	[814]	[396,148,222]	-2	hSpCas9	negative selection	9701578
111079343	111079366	10	-	27869803	ASPC1	viability after 36 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.39420459745274383	[977]	[821,420,203]	4	hSpCas9	negative selection	9701579
111078181	111078204	10	-	27869803	PATU8988S	viability after 35 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	1.462645436688653	[508]	[567,561,NaN]	9	hSpCas9	negative selection	9784023
111078431	111078454	10	+	27869803	PATU8988S	viability after 35 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.49168278886866834	[1707]	[853,1080,NaN]	5	hSpCas9	negative selection	9784024
111078597	111078620	10	-	27869803	PATU8988S	viability after 35 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.5150750671544326	[1489]	[892,821,NaN]	6	hSpCas9	negative selection	9784025
111078604	111078627	10	+	27869803	PATU8988S	viability after 35 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.19312648107735664	[1039]	[313,418,NaN]	-2	hSpCas9	negative selection	9784026
111079246	111079269	10	-	27869803	PATU8988S	viability after 35 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.08657349245645601	[689]	[331,257,NaN]	1	hSpCas9	negative selection	9784027
111079343	111079366	10	-	27869803	PATU8988S	viability after 35 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	-0.48404586057970644	[856]	[148,344,NaN]	-5	hSpCas9	negative selection	9784028
111078181	111078204	10	-	27869803	PATU8988S	viability after 31 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	1.409353837888511	[508]	[440,663,NaN]	9	hSpCas9	negative selection	9866472
111078431	111078454	10	+	27869803	PATU8988S	viability after 31 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.45354006338242736	[1707]	[702,1224,NaN]	5	hSpCas9	negative selection	9866473
111078597	111078620	10	-	27869803	PATU8988S	viability after 31 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.5522750290802256	[1489]	[806,952,NaN]	6	hSpCas9	negative selection	9866474
111078604	111078627	10	+	27869803	PATU8988S	viability after 31 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.1583256233870769	[1039]	[331,421,NaN]	-2	hSpCas9	negative selection	9866475
111079246	111079269	10	-	27869803	PATU8988S	viability after 31 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	-0.32289333294098904	[689]	[215,224,NaN]	-4	hSpCas9	negative selection	9866476
111079343	111079366	10	-	27869803	PATU8988S	viability after 31 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.21985821912429282	[856]	[287,537,NaN]	2	hSpCas9	negative selection	9866477
111078181	111078204	10	-	27869803	HPAFII	viability after 35 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	1.6139042877587748	[184]	[312,256,NaN]	9	hSpCas9	negative selection	9948921
111078431	111078454	10	+	27869803	HPAFII	viability after 35 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.6623928604513016	[669]	[430,655,NaN]	4	hSpCas9	negative selection	9948922
111078597	111078620	10	-	27869803	HPAFII	viability after 35 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.43000992832842866	[858]	[559,614,NaN]	2	hSpCas9	negative selection	9948923
111078604	111078627	10	+	27869803	HPAFII	viability after 35 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.9792218078947319	[680]	[283,51,NaN]	-5	hSpCas9	negative selection	9948924
111079246	111079269	10	-	27869803	HPAFII	viability after 35 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.3386234462637998	[276]	[245,99,NaN]	2	hSpCas9	negative selection	9948925
111079343	111079366	10	-	27869803	HPAFII	viability after 35 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.26986847130550634	[297]	[203,156,NaN]	1	hSpCas9	negative selection	9948926
111078181	111078204	10	-	27869803	HPAFII	viability after 31 days	GACGAGCACGTTGCCGAACACGG	ADRA2A	ENSG00000150594	1.3884672106002296	[184]	[356,178,NaN]	8	hSpCas9	negative selection	10031370
111078431	111078454	10	+	27869803	HPAFII	viability after 31 days	CCGCTACTGGTCCATCACACAGG	ADRA2A	ENSG00000150594	0.517582241885302	[669]	[365,725,NaN]	4	hSpCas9	negative selection	10031371
111078597	111078620	10	-	27869803	HPAFII	viability after 31 days	TGGTCGTTGATCTCGCAGCGCGG	ADRA2A	ENSG00000150594	0.21490645295686295	[858]	[425,704,NaN]	1	hSpCas9	negative selection	10031372
111078604	111078627	10	+	27869803	HPAFII	viability after 31 days	GCGAGATCAACGACCAGAAGTGG	ADRA2A	ENSG00000150594	-0.6259809775897615	[680]	[317,170,NaN]	-4	hSpCas9	negative selection	10031373
111079246	111079269	10	-	27869803	HPAFII	viability after 31 days	TTTGAAGAGCGTGCGTGGCACGG	ADRA2A	ENSG00000150594	0.6851659779370824	[276]	[382,104,NaN]	5	hSpCas9	negative selection	10031374
111079343	111079366	10	-	27869803	HPAFII	viability after 31 days	AGAGGATCTTCTTGAAGGCGCGG	ADRA2A	ENSG00000150594	0.3946252734837023	[297]	[238,198,NaN]	3	hSpCas9	negative selection	10031375
111079340	111079363	10	-	28162770	P31FUJ	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	-1.2328022044143783	[7]	[3]	-7	hSpCas9	negative selection	10107704
111078480	111078503	10	-	28162770	P31FUJ	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.425278225510793	[435]	[687]	5	hSpCas9	negative selection	10107705
111078115	111078138	10	-	28162770	P31FUJ	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.11586227294511131	[138]	[176]	1	hSpCas9	negative selection	10107706
111078329	111078352	10	+	28162770	P31FUJ	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	-0.17435593203082156	[386]	[402]	-2	hSpCas9	negative selection	10107707
111078535	111078558	10	-	28162770	P31FUJ	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	0.6660510721287214	[95]	[178]	7	hSpCas9	negative selection	10107708
111078558	111078581	10	+	28162770	P31FUJ	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	0.4452697006982591	[44]	[71]	5	hSpCas9	negative selection	10107709
111079148	111079171	10	+	28162770	P31FUJ	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.40694158203915964	[266]	[415]	4	hSpCas9	negative selection	10107710
111079234	111079257	10	-	28162770	P31FUJ	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.8470178763827493	[333]	[705]	8	hSpCas9	negative selection	10107711
111077999	111078022	10	+	28162770	P31FUJ	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.42572951430261374	[222]	[351]	5	hSpCas9	negative selection	10107712
111078160	111078183	10	-	28162770	P31FUJ	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	3.6000878097503635	[3]	[56]	9	hSpCas9	negative selection	10107713
111079340	111079363	10	-	28162770	TF1	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10277070
111078480	111078503	10	-	28162770	TF1	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[567]	1	hSpCas9	negative selection	10277071
111078115	111078138	10	-	28162770	TF1	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10277072
111078329	111078352	10	+	28162770	TF1	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10277073
111078535	111078558	10	-	28162770	TF1	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10277074
111078558	111078581	10	+	28162770	TF1	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10277075
111079148	111079171	10	+	28162770	TF1	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10277076
111079234	111079257	10	-	28162770	TF1	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[368]	1	hSpCas9	negative selection	10277077
111077999	111078022	10	+	28162770	TF1	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[123]	1	hSpCas9	negative selection	10277078
111078160	111078183	10	-	28162770	TF1	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10277079
111079340	111079363	10	-	28162770	SKM1	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	2.2368919910315626	[2]	[24]	9	hSpCas9	negative selection	10446436
111078480	111078503	10	-	28162770	SKM1	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.6030198898294605	[107]	[289]	6	hSpCas9	negative selection	10446437
111078115	111078138	10	-	28162770	SKM1	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.5732995831955763	[45]	[120]	5	hSpCas9	negative selection	10446438
111078329	111078352	10	+	28162770	SKM1	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	-0.7132954385795054	[114]	[123]	-5	hSpCas9	negative selection	10446439
111078535	111078558	10	-	28162770	SKM1	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	1.4581062211707296	[27]	[135]	9	hSpCas9	negative selection	10446440
111078558	111078581	10	+	28162770	SKM1	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	0.6727629937275725	[10]	[30]	6	hSpCas9	negative selection	10446441
111079148	111079171	10	+	28162770	SKM1	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	-0.004865755171816172	[62]	[110]	0	hSpCas9	negative selection	10446442
111079234	111079257	10	-	28162770	SKM1	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	-0.1608036114737642	[85]	[135]	-1	hSpCas9	negative selection	10446443
111077999	111078022	10	+	28162770	SKM1	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.2497889850460047	[48]	[102]	2	hSpCas9	negative selection	10446444
111078160	111078183	10	-	28162770	SKM1	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	1.1779983019779952	[0]	[3]	9	hSpCas9	negative selection	10446445
111079340	111079363	10	-	28162770	SKM1	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	2.2368919910315626	[2]	[24]	9	hSpCas9	negative selection	10615802
111078480	111078503	10	-	28162770	SKM1	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.6030198898294605	[107]	[289]	6	hSpCas9	negative selection	10615803
111078115	111078138	10	-	28162770	SKM1	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.5732995831955763	[45]	[120]	5	hSpCas9	negative selection	10615804
111078329	111078352	10	+	28162770	SKM1	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	-0.7132954385795054	[114]	[123]	-5	hSpCas9	negative selection	10615805
111078535	111078558	10	-	28162770	SKM1	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	1.4581062211707296	[27]	[135]	9	hSpCas9	negative selection	10615806
111078558	111078581	10	+	28162770	SKM1	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	0.6727629937275725	[10]	[30]	6	hSpCas9	negative selection	10615807
111079148	111079171	10	+	28162770	SKM1	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	-0.004865755171816172	[62]	[110]	0	hSpCas9	negative selection	10615808
111079234	111079257	10	-	28162770	SKM1	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	-0.1608036114737642	[85]	[135]	-1	hSpCas9	negative selection	10615809
111077999	111078022	10	+	28162770	SKM1	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.2497889850460047	[48]	[102]	2	hSpCas9	negative selection	10615810
111078160	111078183	10	-	28162770	SKM1	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	1.1779983019779952	[0]	[3]	9	hSpCas9	negative selection	10615811
111079340	111079363	10	-	28162770	PL21	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	-1.9697853869529922	[8]	[0]	-8	hSpCas9	negative selection	10785168
111078480	111078503	10	-	28162770	PL21	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.26068115642437095	[279]	[145]	2	hSpCas9	negative selection	10785169
111078115	111078138	10	-	28162770	PL21	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	-0.6317376267023528	[177]	[49]	-4	hSpCas9	negative selection	10785170
111078329	111078352	10	+	28162770	PL21	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	-0.41339203842860694	[458]	[149]	-3	hSpCas9	negative selection	10785171
111078535	111078558	10	-	28162770	PL21	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	-1.0683492214365815	[105]	[21]	-6	hSpCas9	negative selection	10785172
111078558	111078581	10	+	28162770	PL21	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	0.6045298695686555	[67]	[44]	5	hSpCas9	negative selection	10785173
111079148	111079171	10	+	28162770	PL21	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	-1.2148978847895238	[207]	[38]	-7	hSpCas9	negative selection	10785174
111079234	111079257	10	-	28162770	PL21	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.6981299031234739	[244]	[172]	6	hSpCas9	negative selection	10785175
111077999	111078022	10	+	28162770	PL21	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	-0.9353753561671609	[144]	[32]	-6	hSpCas9	negative selection	10785176
111078160	111078183	10	-	28162770	PL21	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	1.20013961448932	[0]	[0]	8	hSpCas9	negative selection	10785177
111079340	111079363	10	-	28162770	P31FUJ	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	-1.2328022044143783	[7]	[3]	-7	hSpCas9	negative selection	10954534
111078480	111078503	10	-	28162770	P31FUJ	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.425278225510793	[435]	[687]	5	hSpCas9	negative selection	10954535
111078115	111078138	10	-	28162770	P31FUJ	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.11586227294511131	[138]	[176]	1	hSpCas9	negative selection	10954536
111078329	111078352	10	+	28162770	P31FUJ	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	-0.17435593203082156	[386]	[402]	-2	hSpCas9	negative selection	10954537
111078535	111078558	10	-	28162770	P31FUJ	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	0.6660510721287214	[95]	[178]	7	hSpCas9	negative selection	10954538
111078558	111078581	10	+	28162770	P31FUJ	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	0.4452697006982591	[44]	[71]	5	hSpCas9	negative selection	10954539
111079148	111079171	10	+	28162770	P31FUJ	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.40694158203915964	[266]	[415]	4	hSpCas9	negative selection	10954540
111079234	111079257	10	-	28162770	P31FUJ	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.8470178763827493	[333]	[705]	8	hSpCas9	negative selection	10954541
111077999	111078022	10	+	28162770	P31FUJ	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.42572951430261374	[222]	[351]	5	hSpCas9	negative selection	10954542
111078160	111078183	10	-	28162770	P31FUJ	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	3.6000878097503635	[3]	[56]	9	hSpCas9	negative selection	10954543
111079340	111079363	10	-	28162770	OCIAML5	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	0.3889415286397977	[10]	[25]	3	hSpCas9	negative selection	11123900
111078480	111078503	10	-	28162770	OCIAML5	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.33444545955009863	[220]	[502]	3	hSpCas9	negative selection	11123901
111078115	111078138	10	-	28162770	OCIAML5	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.9580337279324247	[74]	[262]	8	hSpCas9	negative selection	11123902
111078329	111078352	10	+	28162770	OCIAML5	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.608944352847148	[165]	[456]	5	hSpCas9	negative selection	11123903
111078535	111078558	10	-	28162770	OCIAML5	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	0.3798801571857	[42]	[100]	3	hSpCas9	negative selection	11123904
111078558	111078581	10	+	28162770	OCIAML5	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	1.7508178378544217	[39]	[242]	9	hSpCas9	negative selection	11123905
111079148	111079171	10	+	28162770	OCIAML5	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	1.1996484656801583	[136]	[567]	8	hSpCas9	negative selection	11123906
111079234	111079257	10	-	28162770	OCIAML5	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.6541188164730422	[137]	[391]	6	hSpCas9	negative selection	11123907
111077999	111078022	10	+	28162770	OCIAML5	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.4368212622593577	[105]	[258]	4	hSpCas9	negative selection	11123908
111078160	111078183	10	-	28162770	OCIAML5	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	-2.4370290715851537	[2]	[0]	-8	hSpCas9	negative selection	11123909
111079340	111079363	10	-	28162770	EOL1	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	1.024083445121449	[13]	[14]	8	hSpCas9	negative selection	11293266
111078480	111078503	10	-	28162770	EOL1	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.12771072142692996	[409]	[235]	1	hSpCas9	negative selection	11293267
111078115	111078138	10	-	28162770	EOL1	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.5186935944570262	[260]	[196]	5	hSpCas9	negative selection	11293268
111078329	111078352	10	+	28162770	EOL1	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.5667497202151122	[732]	[571]	5	hSpCas9	negative selection	11293269
111078535	111078558	10	-	28162770	EOL1	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	-0.5429571476024448	[223]	[80]	-4	hSpCas9	negative selection	11293270
111078558	111078581	10	+	28162770	EOL1	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	0.08960701784103087	[131]	[73]	0	hSpCas9	negative selection	11293271
111079148	111079171	10	+	28162770	EOL1	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.9187885022818498	[250]	[249]	7	hSpCas9	negative selection	11293272
111079234	111079257	10	-	28162770	EOL1	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	1.2504230509745597	[291]	[365]	9	hSpCas9	negative selection	11293273
111077999	111078022	10	+	28162770	EOL1	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.2140543887655195	[233]	[142]	2	hSpCas9	negative selection	11293274
111078160	111078183	10	-	28162770	EOL1	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	-0.07545222842946586	[5]	[2]	0	hSpCas9	negative selection	11293275
111079340	111079363	10	-	28162770	MOLM13	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	1.991451337601592	[7]	[22]	9	hSpCas9	negative selection	11462632
111078480	111078503	10	-	28162770	MOLM13	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.6722478800507651	[413]	[476]	5	hSpCas9	negative selection	11462633
111078115	111078138	10	-	28162770	MOLM13	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.28051924564285735	[155]	[136]	2	hSpCas9	negative selection	11462634
111078329	111078352	10	+	28162770	MOLM13	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.2595933034942659	[661]	[572]	1	hSpCas9	negative selection	11462635
111078535	111078558	10	-	28162770	MOLM13	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	-0.30821460652858534	[136]	[79]	-2	hSpCas9	negative selection	11462636
111078558	111078581	10	+	28162770	MOLM13	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	1.9050452868081424	[88]	[240]	9	hSpCas9	negative selection	11462637
111079148	111079171	10	+	28162770	MOLM13	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.03470453555547573	[319]	[236]	0	hSpCas9	negative selection	11462638
111079234	111079257	10	-	28162770	MOLM13	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.6136605212781142	[347]	[384]	4	hSpCas9	negative selection	11462639
111077999	111078022	10	+	28162770	MOLM13	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	1.0655629340152888	[225]	[341]	7	hSpCas9	negative selection	11462640
111078160	111078183	10	-	28162770	MOLM13	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	-0.5321106184554214	[1]	[0]	-3	hSpCas9	negative selection	11462641
111079340	111079363	10	-	28162770	HEL	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	0.6427388320003566	[9]	[9]	5	hSpCas9	negative selection	11631998
111078480	111078503	10	-	28162770	HEL	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.3404152950525058	[401]	[325]	3	hSpCas9	negative selection	11631999
111078115	111078138	10	-	28162770	HEL	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.8184661195092029	[192]	[217]	7	hSpCas9	negative selection	11632000
111078329	111078352	10	+	28162770	HEL	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.9876978955430602	[521]	[662]	8	hSpCas9	negative selection	11632001
111078535	111078558	10	-	28162770	HEL	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	0.49359539269454766	[111]	[100]	4	hSpCas9	negative selection	11632002
111078558	111078581	10	+	28162770	HEL	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	0.8623052092580413	[72]	[84]	7	hSpCas9	negative selection	11632003
111079148	111079171	10	+	28162770	HEL	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	-0.014548506960121554	[316]	[200]	0	hSpCas9	negative selection	11632004
111079234	111079257	10	-	28162770	HEL	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	-0.046059479705339024	[323]	[200]	0	hSpCas9	negative selection	11632005
111077999	111078022	10	+	28162770	HEL	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	-0.009337864579336275	[153]	[97]	0	hSpCas9	negative selection	11632006
111078160	111078183	10	-	28162770	HEL	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	-1.942223668720799	[5]	[0]	-8	hSpCas9	negative selection	11632007
111079340	111079363	10	-	28162770	MV411	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	2.7368223915217005	[12]	[72]	9	hSpCas9	negative selection	11801364
111078480	111078503	10	-	28162770	MV411	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	0.046158116599525734	[406]	[353]	0	hSpCas9	negative selection	11801365
111078115	111078138	10	-	28162770	MV411	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.6032660522884283	[142]	[182]	5	hSpCas9	negative selection	11801366
111078329	111078352	10	+	28162770	MV411	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.5415502678020128	[397]	[487]	5	hSpCas9	negative selection	11801367
111078535	111078558	10	-	28162770	MV411	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	0.14555793676356166	[87]	[81]	1	hSpCas9	negative selection	11801368
111078558	111078581	10	+	28162770	MV411	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	-0.26713562204698293	[109]	[76]	-2	hSpCas9	negative selection	11801369
111079148	111079171	10	+	28162770	MV411	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	1.031179915618429	[175]	[302]	8	hSpCas9	negative selection	11801370
111079234	111079257	10	-	28162770	MV411	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.8719284156905689	[215]	[332]	7	hSpCas9	negative selection	11801371
111077999	111078022	10	+	28162770	MV411	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	-1.2886153494574346	[115]	[39]	-7	hSpCas9	negative selection	11801372
111078160	111078183	10	-	28162770	MV411	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	-2.074490544104587	[4]	[0]	-8	hSpCas9	negative selection	11801373
111079340	111079363	10	-	28162770	MONOMAC1	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	-0.518964941946916	[9]	[7]	-4	hSpCas9	negative selection	11970730
111078480	111078503	10	-	28162770	MONOMAC1	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	1.0508906663840318	[175]	[417]	8	hSpCas9	negative selection	11970731
111078115	111078138	10	-	28162770	MONOMAC1	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.3062012562271487	[114]	[162]	3	hSpCas9	negative selection	11970732
111078329	111078352	10	+	28162770	MONOMAC1	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.18808507431500265	[267]	[349]	2	hSpCas9	negative selection	11970733
111078535	111078558	10	-	28162770	MONOMAC1	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	0.24353574432642788	[55]	[75]	2	hSpCas9	negative selection	11970734
111078558	111078581	10	+	28162770	MONOMAC1	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	0.31541315387723456	[67]	[96]	3	hSpCas9	negative selection	11970735
111079148	111079171	10	+	28162770	MONOMAC1	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.6609441480680185	[111]	[202]	6	hSpCas9	negative selection	11970736
111079234	111079257	10	-	28162770	MONOMAC1	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	1.211499086277335	[138]	[368]	9	hSpCas9	negative selection	11970737
111077999	111078022	10	+	28162770	MONOMAC1	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.07652822626640965	[90]	[109]	0	hSpCas9	negative selection	11970738
111078160	111078183	10	-	28162770	MONOMAC1	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	-1.1970368470595538	[1]	[0]	-7	hSpCas9	negative selection	11970739
111079340	111079363	10	-	28162770	OCIAML2	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	0.2949049211208159	[4]	[33]	3	hSpCas9	negative selection	12140096
111078480	111078503	10	-	28162770	OCIAML2	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	-0.11183643660293652	[84]	[435]	-1	hSpCas9	negative selection	12140097
111078115	111078138	10	-	28162770	OCIAML2	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.6429327335810386	[28]	[250]	6	hSpCas9	negative selection	12140098
111078329	111078352	10	+	28162770	OCIAML2	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.5448332921456431	[57]	[468]	5	hSpCas9	negative selection	12140099
111078535	111078558	10	-	28162770	OCIAML2	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	1.6168330160081783	[9]	[169]	9	hSpCas9	negative selection	12140100
111078558	111078581	10	+	28162770	OCIAML2	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	-0.7394465836699613	[24]	[82]	-5	hSpCas9	negative selection	12140101
111079148	111079171	10	+	28162770	OCIAML2	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.0764360677204664	[44]	[262]	0	hSpCas9	negative selection	12140102
111079234	111079257	10	-	28162770	OCIAML2	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.03043141787004988	[58]	[333]	0	hSpCas9	negative selection	12140103
111077999	111078022	10	+	28162770	OCIAML2	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	0.45828707669635604	[25]	[197]	4	hSpCas9	negative selection	12140104
111078160	111078183	10	-	28162770	OCIAML2	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	-0.47062982524216146	[0]	[3]	-4	hSpCas9	negative selection	12140105
111079340	111079363	10	-	28162770	OCIAML3	viability	GGATCTTCTTGAAGGCGCGGCGG	ADRA2A	ENSG00000150594	2.1064320778169296	[0]	[12]	9	hSpCas9	negative selection	12309462
111078480	111078503	10	-	28162770	OCIAML3	viability	ATGATGGCCTTGATGCGGCGCGG	ADRA2A	ENSG00000150594	-0.5500642927365662	[96]	[199]	-4	hSpCas9	negative selection	12309463
111078115	111078138	10	-	28162770	OCIAML3	viability	CACCTGCAGGGAGTAAGGGGTGG	ADRA2A	ENSG00000150594	0.18128607250114248	[51]	[177]	1	hSpCas9	negative selection	12309464
111078329	111078352	10	+	28162770	OCIAML3	viability	GGGCTACTGGTACTTCGGCAAGG	ADRA2A	ENSG00000150594	0.42685096457350113	[102]	[417]	4	hSpCas9	negative selection	12309465
111078535	111078558	10	-	28162770	OCIAML3	viability	GATGGAGATGAGCGGCGGGAAGG	ADRA2A	ENSG00000150594	1.086112093437333	[21]	[140]	8	hSpCas9	negative selection	12309466
111078558	111078581	10	+	28162770	OCIAML3	viability	GAGAAGAAGGGCGGCGGCGGCGG	ADRA2A	ENSG00000150594	-0.8803118254808044	[24]	[40]	-6	hSpCas9	negative selection	12309467
111079148	111079171	10	+	28162770	OCIAML3	viability	GAAGCGCTTCACGTTCGTGCTGG	ADRA2A	ENSG00000150594	0.7564896067599702	[59]	[305]	6	hSpCas9	negative selection	12309468
111079234	111079257	10	-	28162770	OCIAML3	viability	GCGTGGCACGGAGCACCCGACGG	ADRA2A	ENSG00000150594	0.7944880715021889	[71]	[376]	7	hSpCas9	negative selection	12309469
111077999	111078022	10	+	28162770	OCIAML3	viability	GTTCCGCCAGGAGCAGCCGTTGG	ADRA2A	ENSG00000150594	-0.06002906832181193	[47]	[138]	0	hSpCas9	negative selection	12309470
111078160	111078183	10	-	28162770	OCIAML3	viability	GGTGAGCAGCATGAGCAGGCCGG	ADRA2A	ENSG00000150594	0.405992359675837	[1]	[7]	4	hSpCas9	negative selection	12309471