Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:151
• Symbol:ADRA2B
• Description:adrenoceptor alpha 2B

DataSource: http://genomecrispr.dkfz.de/#!/results/ADRA2B

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
96114829	96114852	2	+	26472758	Jiyoye	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.9161890289937312	[51]	[73]	6	hSpCas9	negative selection	3459
96116098	96116121	2	-	26472758	Jiyoye	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	-1.0496822934675973	[139]	[50]	-6	hSpCas9	negative selection	3460
96115964	96115987	2	+	26472758	Jiyoye	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-1.4715183222719932	[113]	[30]	-7	hSpCas9	negative selection	3461
96115709	96115732	2	+	26472758	Jiyoye	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	0.6702097873396673	[54]	[65]	5	hSpCas9	negative selection	3462
96115642	96115665	2	-	26472758	Jiyoye	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.3532839153272691	[226]	[133]	-3	hSpCas9	negative selection	3463
96115533	96115556	2	-	26472758	Jiyoye	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	1.3641066596139875	[33]	[65]	7	hSpCas9	negative selection	3464
96115246	96115269	2	-	26472758	Jiyoye	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-4.8022779841230765	[36]	[0]	-9	hSpCas9	negative selection	3465
96115030	96115053	2	-	26472758	Jiyoye	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	-1.3090316524935355	[68]	[20]	-7	hSpCas9	negative selection	3466
96114917	96114940	2	+	26472758	Jiyoye	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	2.682182429005743	[24]	[120]	9	hSpCas9	negative selection	3467
96116122	96116145	2	+	26472758	Jiyoye	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.30763970795495876	[179]	[167]	2	hSpCas9	negative selection	3468
96114829	96114852	2	+	26472758	KBM7	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.3975752991004661	[283,109]	[152,84]	4	hSpCas9	negative selection	194577
96116098	96116121	2	-	26472758	KBM7	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	0.4552271547530276	[293,267]	[111,242]	5	hSpCas9	negative selection	194578
96115964	96115987	2	+	26472758	KBM7	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-0.16607129441141766	[301,271]	[68,165]	-2	hSpCas9	negative selection	194579
96115709	96115732	2	+	26472758	KBM7	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	-0.5012526228281884	[228,164]	[51,75]	-4	hSpCas9	negative selection	194580
96115642	96115665	2	-	26472758	KBM7	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	1.0373543345890701	[382,426]	[405,384]	9	hSpCas9	negative selection	194581
96115533	96115556	2	-	26472758	KBM7	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	-0.6735252415773076	[416,260]	[58,132]	-5	hSpCas9	negative selection	194582
96115246	96115269	2	-	26472758	KBM7	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-3.0839717359462226	[250,313]	[7,22]	-9	hSpCas9	negative selection	194583
96115030	96115053	2	-	26472758	KBM7	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	0.4757643057480571	[232,247]	[176,141]	5	hSpCas9	negative selection	194584
96114917	96114940	2	+	26472758	KBM7	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	-0.07690450370382285	[537,397]	[197,213]	0	hSpCas9	negative selection	194585
96116122	96116145	2	+	26472758	KBM7	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.5676246652040383	[1030,726]	[723,497]	6	hSpCas9	negative selection	194586
96114829	96114852	2	+	26472758	Raji	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.5320267493699329	[80]	[12]	-4	hSpCas9	negative selection	385695
96116098	96116121	2	-	26472758	Raji	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	-0.1768248935646043	[150]	[30]	-1	hSpCas9	negative selection	385696
96115964	96115987	2	+	26472758	Raji	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	0.7895251047952843	[176]	[70]	7	hSpCas9	negative selection	385697
96115709	96115732	2	+	26472758	Raji	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	0.5444473409824424	[64]	[21]	5	hSpCas9	negative selection	385698
96115642	96115665	2	-	26472758	Raji	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.4531583722153296	[191]	[60]	4	hSpCas9	negative selection	385699
96115533	96115556	2	-	26472758	Raji	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	0.7568862882894664	[101]	[39]	7	hSpCas9	negative selection	385700
96115246	96115269	2	-	26472758	Raji	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-0.6125085454336652	[111]	[16]	-5	hSpCas9	negative selection	385701
96115030	96115053	2	-	26472758	Raji	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	1.0293810233723266	[94]	[44]	8	hSpCas9	negative selection	385702
96114917	96114940	2	+	26472758	Raji	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.2884095300491619	[186]	[52]	2	hSpCas9	negative selection	385703
96116122	96116145	2	+	26472758	Raji	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.24899814079253446	[445]	[122]	2	hSpCas9	negative selection	385704
96114829	96114852	2	+	26472758	K562	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.06200827368072748	[161]	[130]	0	hSpCas9	negative selection	576813
96116098	96116121	2	-	26472758	K562	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	0.05895287532835633	[314]	[276]	0	hSpCas9	negative selection	576814
96115964	96115987	2	+	26472758	K562	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-0.5881245264819904	[259]	[145]	-4	hSpCas9	negative selection	576815
96115709	96115732	2	+	26472758	K562	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	-0.9627391799748408	[156]	[67]	-5	hSpCas9	negative selection	576816
96115642	96115665	2	-	26472758	K562	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.29886651168882317	[467]	[485]	2	hSpCas9	negative selection	576817
96115533	96115556	2	-	26472758	K562	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	-0.5727172151837425	[184]	[104]	-4	hSpCas9	negative selection	576818
96115246	96115269	2	-	26472758	K562	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-6.523765597110479	[217]	[1]	-9	hSpCas9	negative selection	576819
96115030	96115053	2	-	26472758	K562	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	0.4154642690026742	[142]	[160]	3	hSpCas9	negative selection	576820
96114917	96114940	2	+	26472758	K562	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.6418406840283193	[308]	[406]	5	hSpCas9	negative selection	576821
96116122	96116145	2	+	26472758	K562	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.22590920026368977	[705]	[696]	1	hSpCas9	negative selection	576822
96114829	96114852	2	+	26627737	DLD1	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	1.3499471656820639	[95]	[52,120,59]	9	hSpCas9	negative selection	813116
96115642	96115665	2	+	26627737	DLD1	viability	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.033009296575935876	[297]	[126,76,82]	0	hSpCas9	negative selection	813117
96115642	96115665	2	-	26627737	DLD1	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.49558884368059775	[1432]	[364,256,326]	-5	hSpCas9	negative selection	813118
96115753	96115776	2	+	26627737	DLD1	viability	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.2174591172264138	[442]	[118,239,131]	2	hSpCas9	negative selection	813119
96115754	96115777	2	+	26627737	DLD1	viability	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-0.287795353147155	[288]	[124,16,76]	-3	hSpCas9	negative selection	813120
96116026	96116049	2	+	26627737	DLD1	viability	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	-1.1271784721082285	[128]	[16,28,10]	-7	hSpCas9	negative selection	813121
96114829	96114852	2	+	26627737	GBM cells	viability after 5 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.20425908557744366	[139]	[79,92]	3	hSpCas9	negative selection	895431
96115642	96115665	2	+	26627737	GBM cells	viability after 5 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.4471178255967241	[211]	[118,190]	6	hSpCas9	negative selection	895432
96115642	96115665	2	-	26627737	GBM cells	viability after 5 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.1208493799357443	[440]	[231,202]	-2	hSpCas9	negative selection	895433
96115753	96115776	2	+	26627737	GBM cells	viability after 5 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.06883887632799801	[167]	[96,91]	1	hSpCas9	negative selection	895434
96115754	96115777	2	+	26627737	GBM cells	viability after 5 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-1.3133897288271787	[94]	[28,11]	-9	hSpCas9	negative selection	895435
96116026	96116049	2	+	26627737	GBM cells	viability after 5 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	0.19847415674459334	[38]	[20,26]	3	hSpCas9	negative selection	895436
96114829	96114852	2	+	26627737	GBM cells	viability after 13 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.8945522096663697	[139]	[36,43]	-8	hSpCas9	negative selection	977746
96115642	96115665	2	+	26627737	GBM cells	viability after 13 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.6042415895429031	[211]	[170,177]	7	hSpCas9	negative selection	977747
96115642	96115665	2	-	26627737	GBM cells	viability after 13 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.22434586768547338	[440]	[179,224]	-3	hSpCas9	negative selection	977748
96115753	96115776	2	+	26627737	GBM cells	viability after 13 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.2909709909238614	[167]	[121,102]	4	hSpCas9	negative selection	977749
96115754	96115777	2	+	26627737	GBM cells	viability after 13 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-0.25533340350541267	[94]	[67,22]	-3	hSpCas9	negative selection	977750
96116026	96116049	2	+	26627737	GBM cells	viability after 13 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	-0.03749130252351751	[38]	[13,25]	0	hSpCas9	negative selection	977751
96114829	96114852	2	+	26627737	GBM cells	viability after 21 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.25507350495707815	[139]	[69,57]	-2	hSpCas9	negative selection	1060061
96115642	96115665	2	+	26627737	GBM cells	viability after 21 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	-0.003870764331111276	[211]	[117,111]	0	hSpCas9	negative selection	1060062
96115642	96115665	2	-	26627737	GBM cells	viability after 21 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.2434944734961375	[440]	[216,188]	-2	hSpCas9	negative selection	1060063
96115753	96115776	2	+	26627737	GBM cells	viability after 21 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	1.0586992362418672	[167]	[198,181]	9	hSpCas9	negative selection	1060064
96115754	96115777	2	+	26627737	GBM cells	viability after 21 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-0.9347348065518208	[94]	[26,26]	-7	hSpCas9	negative selection	1060065
96116026	96116049	2	+	26627737	GBM cells	viability after 21 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	0.47202999142512336	[38]	[31,26]	5	hSpCas9	negative selection	1060066
96114829	96114852	2	+	26627737	RPE1	viability after 9 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.24501629945625847	[536]	[133,151]	-2	hSpCas9	negative selection	1142376
96115642	96115665	2	+	26627737	RPE1	viability after 9 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.8745118567675041	[629]	[382,333]	5	hSpCas9	negative selection	1142377
96115642	96115665	2	-	26627737	RPE1	viability after 9 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.6505122412456298	[1776]	[339,372]	-5	hSpCas9	negative selection	1142378
96115753	96115776	2	+	26627737	RPE1	viability after 9 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	-0.1118366441704968	[943]	[362,157]	-1	hSpCas9	negative selection	1142379
96115754	96115777	2	+	26627737	RPE1	viability after 9 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-0.17571619922506054	[594]	[153,178]	-1	hSpCas9	negative selection	1142380
96116026	96116049	2	+	26627737	RPE1	viability after 9 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	1.6705615537258716	[99]	[55,155]	8	hSpCas9	negative selection	1142381
96114829	96114852	2	+	26627737	RPE1	viability after 12 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.8605618539105544	[536]	[77,80]	-5	hSpCas9	negative selection	1224691
96115642	96115665	2	+	26627737	RPE1	viability after 12 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.8186976346487714	[629]	[231,368]	5	hSpCas9	negative selection	1224692
96115642	96115665	2	-	26627737	RPE1	viability after 12 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.2549512487618518	[1776]	[266,540]	-2	hSpCas9	negative selection	1224693
96115753	96115776	2	+	26627737	RPE1	viability after 12 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	-0.855777233527069	[943]	[93,188]	-5	hSpCas9	negative selection	1224694
96115754	96115777	2	+	26627737	RPE1	viability after 12 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	0.05241711673086297	[594]	[225,101]	0	hSpCas9	negative selection	1224695
96116026	96116049	2	+	26627737	RPE1	viability after 12 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	1.4739113864998776	[99]	[44,105]	7	hSpCas9	negative selection	1224696
96114829	96114852	2	+	26627737	RPE1	viability after 15 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.1804044299446036	[536]	[74,190]	-1	hSpCas9	negative selection	1307006
96115642	96115665	2	+	26627737	RPE1	viability after 15 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.38071880364632515	[629]	[173,287]	2	hSpCas9	negative selection	1307007
96115642	96115665	2	-	26627737	RPE1	viability after 15 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.16225334863186913	[1776]	[493,405]	-1	hSpCas9	negative selection	1307008
96115753	96115776	2	+	26627737	RPE1	viability after 15 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.046991528092792	[943]	[338,214]	0	hSpCas9	negative selection	1307009
96115754	96115777	2	+	26627737	RPE1	viability after 15 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-0.2555613818136302	[594]	[225,58]	-2	hSpCas9	negative selection	1307010
96116026	96116049	2	+	26627737	RPE1	viability after 15 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	0.6887687056613929	[99]	[11,77]	4	hSpCas9	negative selection	1307011
96114829	96114852	2	+	26627737	RPE1	viability after 18 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.4734858190701534	[536]	[56,154]	-3	hSpCas9	negative selection	1389321
96115642	96115665	2	+	26627737	RPE1	viability after 18 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.5087017616585101	[629]	[267,213]	3	hSpCas9	negative selection	1389322
96115642	96115665	2	-	26627737	RPE1	viability after 18 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.5034670372138028	[1776]	[229,453]	-3	hSpCas9	negative selection	1389323
96115753	96115776	2	+	26627737	RPE1	viability after 18 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	-0.05059926251116456	[943]	[186,308]	0	hSpCas9	negative selection	1389324
96115754	96115777	2	+	26627737	RPE1	viability after 18 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	0.2824600379215418	[594]	[203,185]	1	hSpCas9	negative selection	1389325
96116026	96116049	2	+	26627737	RPE1	viability after 18 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	0.5139299609331949	[99]	[24,52]	3	hSpCas9	negative selection	1389326
96114829	96114852	2	+	26627737	HeLa	viability after 8 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	1.5959215868093128	[135]	[417,76,99]	9	hSpCas9	negative selection	1471636
96115642	96115665	2	+	26627737	HeLa	viability after 8 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.136657979798685	[338]	[368,44,120]	1	hSpCas9	negative selection	1471637
96115642	96115665	2	-	26627737	HeLa	viability after 8 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.23763348273813456	[858]	[251,504,188]	-2	hSpCas9	negative selection	1471638
96115753	96115776	2	+	26627737	HeLa	viability after 8 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	1.6729852191460093	[120]	[287,42,196]	9	hSpCas9	negative selection	1471639
96115754	96115777	2	+	26627737	HeLa	viability after 8 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	1.321075343302891	[80]	[98,129,40]	8	hSpCas9	negative selection	1471640
96116026	96116049	2	+	26627737	HeLa	viability after 8 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	1.3039730843769788	[36]	[27,38,48]	8	hSpCas9	negative selection	1471641
96114829	96114852	2	+	26627737	HeLa	viability after 12 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	1.8316414650101573	[135]	[268,144,193]	9	hSpCas9	negative selection	1553951
96115642	96115665	2	+	26627737	HeLa	viability after 12 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.0893495284461383	[338]	[137,203,98]	0	hSpCas9	negative selection	1553952
96115642	96115665	2	-	26627737	HeLa	viability after 12 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-1.01402723785312	[858]	[88,258,167]	-7	hSpCas9	negative selection	1553953
96115753	96115776	2	+	26627737	HeLa	viability after 12 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	1.8991718554532413	[120]	[149,143,268]	9	hSpCas9	negative selection	1553954
96115754	96115777	2	+	26627737	HeLa	viability after 12 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	1.1926037422316689	[80]	[20,37,172]	8	hSpCas9	negative selection	1553955
96116026	96116049	2	+	26627737	HeLa	viability after 12 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	1.1552688190387723	[36]	[63,24,14]	8	hSpCas9	negative selection	1553956
96114829	96114852	2	+	26627737	HeLa	viability after 15 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	1.699777768621428	[135]	[198,103,240]	9	hSpCas9	negative selection	1636266
96115642	96115665	2	+	26627737	HeLa	viability after 15 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	-1.071914711535399	[338]	[94,78,18]	-7	hSpCas9	negative selection	1636267
96115642	96115665	2	-	26627737	HeLa	viability after 15 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.68698503007113	[858]	[224,215,209]	-6	hSpCas9	negative selection	1636268
96115753	96115776	2	+	26627737	HeLa	viability after 15 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	1.5338549995142505	[120]	[167,135,121]	8	hSpCas9	negative selection	1636269
96115754	96115777	2	+	26627737	HeLa	viability after 15 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	0.6042449890829522	[80]	[19,89,39]	5	hSpCas9	negative selection	1636270
96116026	96116049	2	+	26627737	HeLa	viability after 15 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	2.239189756412698	[36]	[86,92,29]	9	hSpCas9	negative selection	1636271
96114829	96114852	2	+	26627737	HeLa	viability after 18 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	1.758705634336379	[135]	[144,89,240]	9	hSpCas9	negative selection	1718581
96115642	96115665	2	+	26627737	HeLa	viability after 18 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	-1.2556916602235852	[338]	[55,55,18]	-8	hSpCas9	negative selection	1718582
96115642	96115665	2	-	26627737	HeLa	viability after 18 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.6735622820050158	[858]	[149,184,209]	-5	hSpCas9	negative selection	1718583
96115753	96115776	2	+	26627737	HeLa	viability after 18 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	1.5389846501328133	[120]	[110,115,121]	8	hSpCas9	negative selection	1718584
96115754	96115777	2	+	26627737	HeLa	viability after 18 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	0.664558177161535	[80]	[13,78,39]	5	hSpCas9	negative selection	1718585
96116026	96116049	2	+	26627737	HeLa	viability after 18 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	2.2477238269478006	[36]	[59,75,29]	9	hSpCas9	negative selection	1718586
96114829	96114852	2	+	26627737	HCT116	viability after 6 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-2.7447687953593682	[487]	[4,14]	-9	hSpCas9	negative selection	1800896
96115642	96115665	2	+	26627737	HCT116	viability after 6 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.23646760654817067	[368]	[155,19]	1	hSpCas9	negative selection	1800897
96115642	96115665	2	-	26627737	HCT116	viability after 6 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.18560301697473758	[813]	[131,152]	1	hSpCas9	negative selection	1800898
96115753	96115776	2	+	26627737	HCT116	viability after 6 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.6736573099619825	[707]	[270,125]	4	hSpCas9	negative selection	1800899
96115754	96115777	2	+	26627737	HCT116	viability after 6 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	2.2838573186954343	[145]	[7,168]	9	hSpCas9	negative selection	1800900
96116026	96116049	2	+	26627737	HCT116	viability after 6 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	-2.864718314814784	[277]	[5,5]	-9	hSpCas9	negative selection	1800901
96114829	96114852	2	+	26627737	HCT116	viability after 8 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.6124841937118346	[157]	[131,108,157]	6	hSpCas9	negative selection	1883211
96115642	96115665	2	+	26627737	HCT116	viability after 8 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.6065770972302476	[211]	[157,175,198]	6	hSpCas9	negative selection	1883212
96115642	96115665	2	-	26627737	HCT116	viability after 8 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-1.571624838186139	[1152]	[195,237,206]	-9	hSpCas9	negative selection	1883213
96115753	96115776	2	+	26627737	HCT116	viability after 8 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	-0.000697058009328913	[278]	[176,179,104]	0	hSpCas9	negative selection	1883214
96115754	96115777	2	+	26627737	HCT116	viability after 8 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-1.5532176165061957	[215]	[35,78,6]	-9	hSpCas9	negative selection	1883215
96116026	96116049	2	+	26627737	HCT116	viability after 8 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	1.3994358327522298	[38]	[32,108,27]	9	hSpCas9	negative selection	1883216
96114829	96114852	2	+	26627737	HCT116	viability after 9 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-1.328560785863413	[487]	[52,50]	-7	hSpCas9	negative selection	1965526
96115642	96115665	2	+	26627737	HCT116	viability after 9 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.9771576379975627	[368]	[303,106]	6	hSpCas9	negative selection	1965527
96115642	96115665	2	-	26627737	HCT116	viability after 9 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	1.3689808200822908	[813]	[404,684]	8	hSpCas9	negative selection	1965528
96115753	96115776	2	+	26627737	HCT116	viability after 9 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	-0.9394427646970549	[707]	[135,68]	-6	hSpCas9	negative selection	1965529
96115754	96115777	2	+	26627737	HCT116	viability after 9 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	0.5213592385700516	[145]	[22,81]	4	hSpCas9	negative selection	1965530
96116026	96116049	2	+	26627737	HCT116	viability after 9 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	-0.7386560065773629	[277]	[15,66]	-5	hSpCas9	negative selection	1965531
96114829	96114852	2	+	26627737	HCT116	viability after 12 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.8738294247304992	[157]	[171,162,119]	7	hSpCas9	negative selection	2047841
96115642	96115665	2	+	26627737	HCT116	viability after 12 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.44972773838537466	[211]	[167,147,138]	4	hSpCas9	negative selection	2047842
96115642	96115665	2	-	26627737	HCT116	viability after 12 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-1.2385041823679661	[1152]	[263,224,279]	-8	hSpCas9	negative selection	2047843
96115753	96115776	2	+	26627737	HCT116	viability after 12 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.3499055088209673	[278]	[207,114,233]	3	hSpCas9	negative selection	2047844
96115754	96115777	2	+	26627737	HCT116	viability after 12 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-0.3717190953524229	[215]	[62,113,88]	-4	hSpCas9	negative selection	2047845
96116026	96116049	2	+	26627737	HCT116	viability after 12 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	0.6465147609879098	[38]	[13,79,4]	6	hSpCas9	negative selection	2047846
96114829	96114852	2	+	26627737	HCT116	viability after 15 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.6254805937560273	[157]	[203,104,118]	6	hSpCas9	negative selection	2130156
96115642	96115665	2	+	26627737	HCT116	viability after 15 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.6333391921886273	[211]	[247,239,86]	6	hSpCas9	negative selection	2130157
96115642	96115665	2	-	26627737	HCT116	viability after 15 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-1.1134369145009277	[1152]	[202,346,354]	-8	hSpCas9	negative selection	2130158
96115753	96115776	2	+	26627737	HCT116	viability after 15 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.07426545528326661	[278]	[218,107,184]	0	hSpCas9	negative selection	2130159
96115754	96115777	2	+	26627737	HCT116	viability after 15 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-1.632981197319052	[215]	[37,62,18]	-9	hSpCas9	negative selection	2130160
96116026	96116049	2	+	26627737	HCT116	viability after 15 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	0.464873602501902	[38]	[0,48,38]	4	hSpCas9	negative selection	2130161
96114829	96114852	2	+	26627737	HCT116	viability after 18 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.7178390146182952	[157]	[172,130,69]	6	hSpCas9	negative selection	2212471
96115642	96115665	2	+	26627737	HCT116	viability after 18 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.40462921551618103	[211]	[150,120,135]	3	hSpCas9	negative selection	2212472
96115642	96115665	2	-	26627737	HCT116	viability after 18 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.6483033816608588	[1152]	[318,395,348]	-5	hSpCas9	negative selection	2212473
96115753	96115776	2	+	26627737	HCT116	viability after 18 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.0021613885095564805	[278]	[92,145,166]	0	hSpCas9	negative selection	2212474
96115754	96115777	2	+	26627737	HCT116	viability after 18 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	-0.9587813093213775	[215]	[101,43,13]	-7	hSpCas9	negative selection	2212475
96116026	96116049	2	+	26627737	HCT116	viability after 18 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	0.5376134225416678	[38]	[3,54,20]	4	hSpCas9	negative selection	2212476
96116110	96116133	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACTCCGTGCAGGCCACAGCGG	ADRA2B	ENSG00000274286	0.048469443594449185	[2,3]	[2,2]	1	hSpCas9	positive selection	2969207
96115839	96115862	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACAGGTGCACGATGGACGAGG	ADRA2B	ENSG00000274286	-0.42297220632646126	[1,3]	[1,0]	-6	hSpCas9	positive selection	2969208
96115693	96115716	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	-0.08459431132993261	[2,2]	[3,0]	-1	hSpCas9	positive selection	2969209
96115784	96115807	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.0427238335973526	[4,4]	[4,2]	0	hSpCas9	positive selection	2969210
96116110	96116133	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACTCCGTGCAGGCCACAGCGG	ADRA2B	ENSG00000274286	0.539899546634399	[2,2]	[2,3]	8	hSpCas9	positive selection	3037065
96115839	96115862	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACAGGTGCACGATGGACGAGG	ADRA2B	ENSG00000274286	1.0547502785439744	[1,1]	[2,2]	9	hSpCas9	positive selection	3037066
96115693	96115716	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.41787823993504286	[2,2]	[4,1]	7	hSpCas9	positive selection	3037067
96115784	96115807	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.11309421282820217	[4,4]	[4,1]	2	hSpCas9	positive selection	3037068
96114817	96114840		+	24336571	A375	resistance to PLX after 7 days	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.1627572864321099	[9,7]	[7,7]	-5	hSpCas9	positive selection	3107296
96115400	96115423		+	24336571	A375	resistance to PLX after 7 days	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.20601476657191564	[27,29]	[34,31]	6	hSpCas9	positive selection	3107303
96115055	96115078		-	24336571	A375	resistance to PLX after 7 days	GTCGACGGGCGCAGCTGACCCGG	ADRA2B	ENSG00000274286	0.3338410844209212	[2,2]	[3,2]	8	hSpCas9	positive selection	3107313
96114817	96114840		+	24336571	A375	resistance to PLX after 14 days	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.5507015066829977	[12,7]	[2,2]	-6	hSpCas9	positive selection	3165089
96115400	96115423		+	24336571	A375	resistance to PLX after 14 days	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	3.6660654141481905	[22,31]	[145,183]	9	hSpCas9	positive selection	3165096
96115055	96115078		-	24336571	A375	resistance to PLX after 14 days	GTCGACGGGCGCAGCTGACCCGG	ADRA2B	ENSG00000274286	2.161020252861259	[1,1]	[3,5]	9	hSpCas9	positive selection	3165106
96114817	96114840		+	24336571	A375	viability after 7 days	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.4898696865687248	[6]	[9,7]	7	hSpCas9	negative selection	3222882
96115400	96115423		+	24336571	A375	viability after 7 days	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.9163897073403882	[15]	[27,29]	9	hSpCas9	negative selection	3222889
96115055	96115078		-	24336571	A375	viability after 7 days	GTCGACGGGCGCAGCTGACCCGG	ADRA2B	ENSG00000274286	0.4053837432752174	[1]	[2,2]	6	hSpCas9	negative selection	3222899
96114817	96114840		+	24336571	A375	viability after 14 days	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.7262005543120228	[6]	[12,7]	8	hSpCas9	negative selection	3280675
96115400	96115423		+	24336571	A375	viability after 14 days	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.847523588114292	[15]	[22,31]	9	hSpCas9	negative selection	3280682
96115055	96115078		-	24336571	A375	viability after 14 days	GTCGACGGGCGCAGCTGACCCGG	ADRA2B	ENSG00000274286	-0.05161935173889631	[1]	[1,1]	0	hSpCas9	negative selection	3280692
96114817	96114840	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	2.089760482877445	[26,44]	[0,0]	7	hSpCas9	positive selection	3335788
96115783	96115806	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.5413754333381264	[123,85]	[0,0]	2	hSpCas9	positive selection	3335789
96115389	96115412	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.2678992448461766	[136,116]	[0,0]	1	hSpCas9	positive selection	3335790
96115552	96115575	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	1.8310614567437373	[42,42]	[0,0]	7	hSpCas9	positive selection	3355037
96115400	96115423	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-2.1499415527988965	[678,678]	[0,0]	-9	hSpCas9	positive selection	3355038
96115891	96115914	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.48914188666890873	[108,108]	[0,0]	2	hSpCas9	positive selection	3355039
96116110	96116133	2	-	26780180	HT29	viability (Avana library 4 designs)	CTACTCCGTGCAGGCCACAGCGG	ADRA2B	ENSG00000274286	0.8159428789861	[]	[]	3	hSpCas9	negative selection	3405273
96115838	96115861	2	+	26780180	HT29	viability (Avana library 4 designs)	GCACAGGTGCACGATGGACGAGG	ADRA2B	ENSG00000274286	0.573267945489318	[]	[]	2	hSpCas9	negative selection	3405274
96115692	96115715	2	+	26780180	HT29	viability (Avana library 4 designs)	TCGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	1.56534675292986	[]	[]	6	hSpCas9	negative selection	3405275
96115783	96115806	2	+	26780180	HT29	viability (Avana library 4 designs)	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	1.06742293506559	[]	[]	4	hSpCas9	negative selection	3405276
96115692	96115715	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	4.49956448734203	[]	[]	7	hSpCas9	negative selection	3477202
96115783	96115806	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	6.40855601662952	[]	[]	9	hSpCas9	negative selection	3477203
96115838	96115861	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACAGGTGCACGATGGACGAGG	ADRA2B	ENSG00000274286	5.97851884564402	[]	[]	9	hSpCas9	negative selection	3477204
96116110	96116133	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACTCCGTGCAGGCCACAGCGG	ADRA2B	ENSG00000274286	4.09207580370579	[]	[]	6	hSpCas9	negative selection	3477205
96115671	96115694	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GACCAGGGCCCCCAGCCGCGCGG	ADRA2B	ENSG00000274286	2.84365357653112	[]	[]	4	hSpCas9	negative selection	3477206
96115517	96115540	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAGGTCCCAGGGCCAAGGGG	ADRA2B	ENSG00000274286	7.5752798279425	[]	[]	9	hSpCas9	negative selection	3477207
96115692	96115715	2	+	26780180	A375	viability (Avana lentiGuide)	TCGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	-1.54992968114645	[]	[]	-3	hSpCas9	negative selection	3585861
96115783	96115806	2	+	26780180	A375	viability (Avana lentiGuide)	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.598480949160443	[]	[]	-1	hSpCas9	negative selection	3585862
96115838	96115861	2	+	26780180	A375	viability (Avana lentiGuide)	GCACAGGTGCACGATGGACGAGG	ADRA2B	ENSG00000274286	4.23154161436514	[]	[]	4	hSpCas9	negative selection	3585863
96116110	96116133	2	-	26780180	A375	viability (Avana lentiGuide)	CTACTCCGTGCAGGCCACAGCGG	ADRA2B	ENSG00000274286	5.37067019756403	[]	[]	5	hSpCas9	negative selection	3585864
96115671	96115694	2	-	26780180	A375	viability (Avana lentiGuide)	GACCAGGGCCCCCAGCCGCGCGG	ADRA2B	ENSG00000274286	3.13019964921464	[]	[]	3	hSpCas9	negative selection	3585865
96115517	96115540	2	-	26780180	A375	viability (Avana lentiGuide)	GCAGAGGTCCCAGGGCCAAGGGG	ADRA2B	ENSG00000274286	-4.23999478104749	[]	[]	-7	hSpCas9	negative selection	3585866
96115692	96115715	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.2493388878708674	[4]	[5,4]	7	hSpCas9	positive selection	3694520
96115783	96115806	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.260332833721276	[5]	[7,6]	7	hSpCas9	positive selection	3694521
96115838	96115861	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACAGGTGCACGATGGACGAGG	ADRA2B	ENSG00000274286	0.30513651581423246	[4]	[6,4]	8	hSpCas9	positive selection	3694522
96116110	96116133	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACTCCGTGCAGGCCACAGCGG	ADRA2B	ENSG00000274286	0.30730885100425054	[4]	[5,5]	8	hSpCas9	positive selection	3694523
96115671	96115694	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACCAGGGCCCCCAGCCGCGCGG	ADRA2B	ENSG00000274286	0.37263946255975755	[3]	[4,4]	9	hSpCas9	positive selection	3694524
96115517	96115540	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAGGTCCCAGGGCCAAGGGG	ADRA2B	ENSG00000274286	0.37431954270256407	[3]	[5,4]	9	hSpCas9	positive selection	3694525
96115692	96115715	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	-0.20893173959814168	[4]	[1,4]	-3	hSpCas9	positive selection	3803127
96115783	96115806	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.1481301993226236	[6]	[6,5]	3	hSpCas9	positive selection	3803128
96115838	96115861	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACAGGTGCACGATGGACGAGG	ADRA2B	ENSG00000274286	-0.2958079790135978	[5]	[2,3]	-4	hSpCas9	positive selection	3803129
96116110	96116133	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACTCCGTGCAGGCCACAGCGG	ADRA2B	ENSG00000274286	-0.35202110784495255	[5]	[3,2]	-5	hSpCas9	positive selection	3803130
96115671	96115694	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACCAGGGCCCCCAGCCGCGCGG	ADRA2B	ENSG00000274286	0.15085721872229144	[4]	[2,4]	3	hSpCas9	positive selection	3803131
96115517	96115540	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAGGTCCCAGGGCCAAGGGG	ADRA2B	ENSG00000274286	0.07120770086652733	[4]	[3,4]	1	hSpCas9	positive selection	3803132
96115389	96115412	2	-	26780180	A375	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	1.72429551808133	[]	[]	9	hSpCas9	negative selection	3911592
96114817	96114840	2	+	26780180	A375	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.999446266378601	[]	[]	4	hSpCas9	negative selection	3911593
96115400	96115423	2	+	26780180	A375	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.782776408454708	[]	[]	3	hSpCas9	negative selection	3911594
96115891	96115914	2	-	26780180	A375	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.321132980625872	[]	[]	0	hSpCas9	negative selection	3911595
96115783	96115806	2	+	26780180	A375	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.513180769321755	[]	[]	1	hSpCas9	negative selection	3911596
96115552	96115575	2	+	26780180	A375	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	0.599897375049842	[]	[]	1	hSpCas9	negative selection	3911597
96115389	96115412	2	-	26780180	HT29	viability (GeCKOv2 library)	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	1.58346189419287	[]	[]	8	hSpCas9	negative selection	4019558
96114817	96114840	2	+	26780180	HT29	viability (GeCKOv2 library)	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	1.40787766198383	[]	[]	7	hSpCas9	negative selection	4019559
96115400	96115423	2	+	26780180	HT29	viability (GeCKOv2 library)	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.657626611999718	[]	[]	2	hSpCas9	negative selection	4019560
96115891	96115914	2	-	26780180	HT29	viability (GeCKOv2 library)	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.181717655424748	[]	[]	0	hSpCas9	negative selection	4019561
96115783	96115806	2	+	26780180	HT29	viability (GeCKOv2 library)	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.908738005098487	[]	[]	4	hSpCas9	negative selection	4019562
96115552	96115575	2	+	26780180	HT29	viability (GeCKOv2 library)	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	1.33064651581754	[]	[]	6	hSpCas9	negative selection	4019563
96114817	96114840	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.011428821537177669	[2]	[1,1]	0	hSpCas9	positive selection	4129546
96115400	96115423	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.7190894229969921	[4]	[2,7]	9	hSpCas9	positive selection	4129557
96115055	96115078	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCGACGGGCGCAGCTGACCCGG	ADRA2B	ENSG00000274286	1.4764761180529038	[0]	[1,2]	9	hSpCas9	positive selection	4129568
96114817	96114840	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.3394282634667972	[3]	[1,3,2,0]	2	hSpCas9	positive selection	4193568
96115400	96115423	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.2603247629771177	[4]	[4,1,3,0]	2	hSpCas9	positive selection	4193579
96115055	96115078	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCGACGGGCGCAGCTGACCCGG	ADRA2B	ENSG00000274286	2.109513552895172	[0]	[0,0,0,3]	9	hSpCas9	positive selection	4193590
96114817	96114840	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.22988079494720481	[2]	[2,1]	4	hSpCas9	positive selection	4254752
96115783	96115806	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.2974996794059397	[2]	[2,2]	6	hSpCas9	positive selection	4254753
96115389	96115412	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.2174221678581828	[2]	[2,1]	-4	hSpCas9	positive selection	4254754
96115552	96115575	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	0.11928495638660341	[1]	[2,0]	2	hSpCas9	positive selection	4319034
96115400	96115423	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.011368330130060833	[4]	[4,2]	0	hSpCas9	positive selection	4319035
96115891	96115914	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.10079948054735327	[2]	[2,1]	2	hSpCas9	positive selection	4319036
96115466	96115488	2	+	27760321	OCIAML3	viability	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	-0.21243520492460077	[813,634]	[341,672]	-2	hSpCas9	negative selection	4376526
96115541	96115563	2	+	27760321	OCIAML3	viability	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.03379204916502254	[1078,967]	[711,870]	0	hSpCas9	negative selection	4376527
96115693	96115715	2	+	27760321	OCIAML3	viability	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	-0.14627289732293927	[575,457]	[307,434]	-1	hSpCas9	negative selection	4376528
96115730	96115752	2	+	27760321	OCIAML3	viability	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	-0.5001558358590625	[340,302]	[172,183]	-5	hSpCas9	negative selection	4376529
96115891	96115913	2	-	27760321	OCIAML3	viability	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.5341607368222487	[848,710]	[822,953]	6	hSpCas9	negative selection	4376530
96115466	96115488	2	+	27760321	OCIAML2	viability	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	0.23792807156100582	[813,634]	[663,715]	3	hSpCas9	negative selection	4459989
96115541	96115563	2	+	27760321	OCIAML2	viability	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.21104524400899805	[1078,967]	[584,884]	-3	hSpCas9	negative selection	4459990
96115693	96115715	2	+	27760321	OCIAML2	viability	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.2585708407407704	[575,457]	[413,606]	3	hSpCas9	negative selection	4459991
96115730	96115752	2	+	27760321	OCIAML2	viability	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	-0.1736292222996344	[340,302]	[227,233]	-2	hSpCas9	negative selection	4459992
96115891	96115913	2	-	27760321	OCIAML2	viability	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.569808464018738	[848,710]	[805,1099]	7	hSpCas9	negative selection	4459993
96115466	96115488	2	+	27760321	MV411	viability	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	1.2733714130669336	[813,634]	[1584,490]	8	hSpCas9	negative selection	4543452
96115541	96115563	2	+	27760321	MV411	viability	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.008583283912142026	[1078,967]	[692,636]	0	hSpCas9	negative selection	4543453
96115693	96115715	2	+	27760321	MV411	viability	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	-1.237957708855647	[575,457]	[102,204]	-7	hSpCas9	negative selection	4543454
96115730	96115752	2	+	27760321	MV411	viability	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	1.0716451599191679	[340,302]	[586,233]	7	hSpCas9	negative selection	4543455
96115891	96115913	2	-	27760321	MV411	viability	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.9520652112658157	[848,710]	[801,1276]	7	hSpCas9	negative selection	4543456
96115466	96115488	2	+	27760321	HL60	viability	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	-0.24436375852872688	[813,634]	[402,594]	-3	hSpCas9	negative selection	4626915
96115541	96115563	2	+	27760321	HL60	viability	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	0.1705478963836511	[1078,967]	[869,1013]	2	hSpCas9	negative selection	4626916
96115693	96115715	2	+	27760321	HL60	viability	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.2957117196900386	[575,457]	[423,611]	3	hSpCas9	negative selection	4626917
96115730	96115752	2	+	27760321	HL60	viability	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	0.4478019448796787	[340,302]	[447,262]	5	hSpCas9	negative selection	4626918
96115891	96115913	2	-	27760321	HL60	viability	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.3545226668045338	[848,710]	[907,708]	4	hSpCas9	negative selection	4626919
96115466	96115488	2	+	27760321	HT1080	viability	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	1.4783570423961663	[634,495]	[895,333]	7	hSpCas9	negative selection	4710378
96115541	96115563	2	+	27760321	HT1080	viability	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	0.6849464732392834	[967,755]	[479,630]	3	hSpCas9	negative selection	4710379
96115693	96115715	2	+	27760321	HT1080	viability	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.549967142697685	[457,357]	[205,272]	3	hSpCas9	negative selection	4710380
96115730	96115752	2	+	27760321	HT1080	viability	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	1.5237643840228623	[302,236]	[431,174]	8	hSpCas9	negative selection	4710381
96115891	96115913	2	-	27760321	HT1080	viability	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.5526874585383194	[710,554]	[356,383]	3	hSpCas9	negative selection	4710382
96115466	96115488	2	+	27760321	HT29	viability after 7 days	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	0.5092120790148167	[634,495]	[884,1169,1026]	7	hSpCas9	negative selection	4793841
96115541	96115563	2	+	27760321	HT29	viability after 7 days	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.26515109198437947	[967,755]	[905,994,863]	-4	hSpCas9	negative selection	4793842
96115693	96115715	2	+	27760321	HT29	viability after 7 days	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.11147831908862618	[457,357]	[682,432,598]	1	hSpCas9	negative selection	4793843
96115730	96115752	2	+	27760321	HT29	viability after 7 days	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	-0.46289571140333724	[302,236]	[426,123,229]	-6	hSpCas9	negative selection	4793844
96115891	96115913	2	-	27760321	HT29	viability after 7 days	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.2908277562340017	[710,554]	[985,967,1028]	4	hSpCas9	negative selection	4793845
96115466	96115488	2	+	27760321	HT29	viability after 25 days	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	0.4031537939592513	[634,495]	[752,901,920]	4	hSpCas9	negative selection	4877304
96115541	96115563	2	+	27760321	HT29	viability after 25 days	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.591745517014633	[967,755]	[676,434,868]	-5	hSpCas9	negative selection	4877305
96115693	96115715	2	+	27760321	HT29	viability after 25 days	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.10810319778336283	[457,357]	[557,395,554]	1	hSpCas9	negative selection	4877306
96115730	96115752	2	+	27760321	HT29	viability after 25 days	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	-0.31273079488444394	[302,236]	[263,205,276]	-3	hSpCas9	negative selection	4877307
96115891	96115913	2	-	27760321	HT29	viability after 25 days	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.5787321415602343	[710,554]	[1049,1150,1035]	6	hSpCas9	negative selection	4877308
96115466	96115488	2	+	27760321	HT29	viability after 22 days	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	0.7097839510697821	[634,495]	[1077,1018,1110]	7	hSpCas9	negative selection	4960767
96115541	96115563	2	+	27760321	HT29	viability after 22 days	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.3997306775956396	[967,755]	[1075,579,599]	-4	hSpCas9	negative selection	4960768
96115693	96115715	2	+	27760321	HT29	viability after 22 days	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.17168512816257805	[457,357]	[492,673,426]	1	hSpCas9	negative selection	4960769
96115730	96115752	2	+	27760321	HT29	viability after 22 days	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	-0.0755281080190025	[302,236]	[313,305,267]	-1	hSpCas9	negative selection	4960770
96115891	96115913	2	-	27760321	HT29	viability after 22 days	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.6238551944436487	[710,554]	[1070,1029,1284]	7	hSpCas9	negative selection	4960771
96115466	96115488	2	+	27760321	HT29	viability after 19 days	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	0.8448942267605326	[634,495]	[971,808,1663]	8	hSpCas9	negative selection	5044230
96115541	96115563	2	+	27760321	HT29	viability after 19 days	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.2495218871034386	[967,755]	[1102,663,751]	-2	hSpCas9	negative selection	5044231
96115693	96115715	2	+	27760321	HT29	viability after 19 days	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	-0.5286301100850171	[457,357]	[360,337,276]	-4	hSpCas9	negative selection	5044232
96115730	96115752	2	+	27760321	HT29	viability after 19 days	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	-0.44645756732954983	[302,236]	[440,82,179]	-4	hSpCas9	negative selection	5044233
96115891	96115913	2	-	27760321	HT29	viability after 19 days	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.4310751806945793	[710,554]	[973,834,1112]	4	hSpCas9	negative selection	5044234
96115466	96115488	2	+	27760321	HT29	viability after 16 days	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	0.22563773016069277	[634,495]	[794,723,705]	2	hSpCas9	negative selection	5127693
96115541	96115563	2	+	27760321	HT29	viability after 16 days	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.44523118231726877	[967,755]	[720,445,965]	-4	hSpCas9	negative selection	5127694
96115693	96115715	2	+	27760321	HT29	viability after 16 days	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.33030945570364434	[457,357]	[522,573,619]	3	hSpCas9	negative selection	5127695
96115730	96115752	2	+	27760321	HT29	viability after 16 days	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	0.2185642618419489	[302,236]	[313,236,502]	2	hSpCas9	negative selection	5127696
96115891	96115913	2	-	27760321	HT29	viability after 16 days	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.21592972659853416	[710,554]	[777,872,810]	2	hSpCas9	negative selection	5127697
96115466	96115488	2	+	27760321	HT29	viability after 13 days	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	0.7018321560272958	[634,495]	[1533,783,892]	8	hSpCas9	negative selection	5211156
96115541	96115563	2	+	27760321	HT29	viability after 13 days	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.7464835310921408	[967,755]	[657,567,563]	-6	hSpCas9	negative selection	5211157
96115693	96115715	2	+	27760321	HT29	viability after 13 days	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.20926220610920118	[457,357]	[673,532,440]	2	hSpCas9	negative selection	5211158
96115730	96115752	2	+	27760321	HT29	viability after 13 days	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	-0.2437885003512415	[302,236]	[203,396,196]	-3	hSpCas9	negative selection	5211159
96115891	96115913	2	-	27760321	HT29	viability after 13 days	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.4685167741599737	[710,554]	[1051,1080,920]	6	hSpCas9	negative selection	5211160
96115466	96115488	2	+	27760321	HT29	viability after 10 days	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	0.6471774579346203	[634,495]	[1095,1104,1115]	8	hSpCas9	negative selection	5294619
96115541	96115563	2	+	27760321	HT29	viability after 10 days	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.6942572159796588	[967,755]	[761,572,657]	-7	hSpCas9	negative selection	5294620
96115693	96115715	2	+	27760321	HT29	viability after 10 days	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	-0.22678414985288964	[457,357]	[298,636,376]	-3	hSpCas9	negative selection	5294621
96115730	96115752	2	+	27760321	HT29	viability after 10 days	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	-0.27422261762417793	[302,236]	[189,371,276]	-3	hSpCas9	negative selection	5294622
96115891	96115913	2	-	27760321	HT29	viability after 10 days	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.21812429353382734	[710,554]	[758,1213,795]	3	hSpCas9	negative selection	5294623
96115466	96115488	2	+	27760321	MOLM13	viability	AGCCCCACCATGGTCGGGTCGG	ADRA2B	ENSG00000274286	0.9230824419340137	[813,634]	[503,995]	6	hSpCas9	negative selection	5378082
96115541	96115563	2	+	27760321	MOLM13	viability	GTTGCTGCGTTTGGCGATCAGG	ADRA2B	ENSG00000274286	-0.1845083437976449	[1078,967]	[385,610]	-1	hSpCas9	negative selection	5378083
96115693	96115715	2	+	27760321	MOLM13	viability	CGCCCTTGTAGATGAGGGGCGG	ADRA2B	ENSG00000274286	0.2903647944369775	[575,457]	[252,440]	2	hSpCas9	negative selection	5378084
96115730	96115752	2	+	27760321	MOLM13	viability	GGCGATGAGCCACACAGTGAGG	ADRA2B	ENSG00000274286	-0.1735610879601448	[340,302]	[337,9]	-1	hSpCas9	negative selection	5378085
96115891	96115913	2	-	27760321	MOLM13	viability	TTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	1.344382321035213	[848,710]	[1677,631]	8	hSpCas9	negative selection	5378086
96116134	96116157	2	+	27661255	K562	viability	GGTCCTGGTGGTCCATGACGGGG	ADRA2B	ENSG00000274286	0.14729797679590506	[991,1077]	[991,847]	5	dCas9-KRAB	negative selection	5461189
96116101	96116124	2	-	27661255	K562	viability	GCAGGCCACAGCGGCCATAGCGG	ADRA2B	ENSG00000274286	-0.09594013958368475	[308,540]	[320,308]	-4	dCas9-KRAB	negative selection	5461190
96114817	96114840	2	+	27260156	BXPC3	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.06735005610074873	[209]	[217,172,208,241]	-1	hSpCas9	negative selection	5527212
96115783	96115806	2	+	27260156	BXPC3	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.10410219593663762	[437]	[355,502,574,554]	2	hSpCas9	negative selection	5527213
96115389	96115412	2	-	27260156	BXPC3	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.33038717108689253	[398]	[260,402,326,337]	-6	hSpCas9	negative selection	5527214
96115552	96115575	2	+	27260156	BXPC3	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.6620058087089329	[116]	[95,108,43,51]	-8	hSpCas9	negative selection	5591494
96115400	96115423	2	+	27260156	BXPC3	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.25463761115967243	[1170]	[898,967,1008,1268]	-5	hSpCas9	negative selection	5591495
96115891	96115914	2	-	27260156	BXPC3	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	-0.0002721154034592832	[332]	[254,312,379,469]	0	hSpCas9	negative selection	5591496
96114817	96114840	2	+	27260156	A673	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.010234882440321558	[209]	[237,195,286,295]	0	hSpCas9	negative selection	5648463
96115783	96115806	2	+	27260156	A673	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.15337169243185808	[437]	[605,536,553,648]	3	hSpCas9	negative selection	5648464
96115389	96115412	2	-	27260156	A673	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.3306304619617838	[398]	[351,381,382,403]	-7	hSpCas9	negative selection	5648465
96115552	96115575	2	+	27260156	A673	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.2759680480147342	[116]	[188,57,137,86]	-6	hSpCas9	negative selection	5712745
96115400	96115423	2	+	27260156	A673	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.14544502311672058	[1170]	[1584,1234,1185,1104]	-4	hSpCas9	negative selection	5712746
96115891	96115914	2	-	27260156	A673	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.1389224066985157	[332]	[388,407,478,480]	3	hSpCas9	negative selection	5712747
96114817	96114840	2	+	27260156	A375	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.10766126912924201	[209]	[241,374,223,233]	1	hSpCas9	negative selection	5769714
96115783	96115806	2	+	27260156	A375	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.13703627449458355	[437]	[518,565,561,596]	2	hSpCas9	negative selection	5769715
96115389	96115412	2	-	27260156	A375	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.47845895268453315	[398]	[676,796,737,429]	7	hSpCas9	negative selection	5769716
96115552	96115575	2	+	27260156	A375	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.2703573566993329	[116]	[131,126,111,86]	-4	hSpCas9	negative selection	5833996
96115400	96115423	2	+	27260156	A375	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.05101663059175521	[1170]	[1416,1541,1574,1174]	0	hSpCas9	negative selection	5833997
96115891	96115914	2	-	27260156	A375	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	-0.10646582707910723	[332]	[255,383,397,402]	-1	hSpCas9	negative selection	5833998
96114817	96114840	2	+	27260156	COLO741	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.042118620979307186	[209]	[237,275,264]	-1	hSpCas9	negative selection	5890965
96115783	96115806	2	+	27260156	COLO741	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.25341209961604294	[437]	[595,926,484]	5	hSpCas9	negative selection	5890966
96115389	96115412	2	-	27260156	COLO741	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.07202978770143345	[398]	[630,497,488]	1	hSpCas9	negative selection	5890967
96115552	96115575	2	+	27260156	COLO741	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.8034789141476275	[116]	[98,74,83]	-9	hSpCas9	negative selection	5955247
96115400	96115423	2	+	27260156	COLO741	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.07306911579231667	[1170]	[1527,1482,1272]	-1	hSpCas9	negative selection	5955248
96115891	96115914	2	-	27260156	COLO741	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.22346800278466883	[332]	[382,686,415]	5	hSpCas9	negative selection	5955249
96114817	96114840	2	+	27260156	CAL120	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.7065061600965115	[209]	[97,156,214]	-7	hSpCas9	negative selection	6012216
96115783	96115806	2	+	27260156	CAL120	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.5389685600841838	[437]	[1019,445,940]	7	hSpCas9	negative selection	6012217
96115389	96115412	2	-	27260156	CAL120	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.1656450678947757	[398]	[307,471,525]	-2	hSpCas9	negative selection	6012218
96115552	96115575	2	+	27260156	CAL120	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-1.0228028401701796	[116]	[10,21,170]	-8	hSpCas9	negative selection	6076498
96115400	96115423	2	+	27260156	CAL120	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.13688802860039728	[1170]	[2532,921,1492]	2	hSpCas9	negative selection	6076499
96115891	96115914	2	-	27260156	CAL120	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	-0.17120799452138524	[332]	[366,327,407]	-3	hSpCas9	negative selection	6076500
96114817	96114840	2	+	27260156	CADOES1	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.21185015846802502	[209]	[158,157,151,206]	-4	hSpCas9	negative selection	6133467
96115783	96115806	2	+	27260156	CADOES1	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.08980120445278311	[437]	[478,290,470,494]	1	hSpCas9	negative selection	6133468
96115389	96115412	2	-	27260156	CADOES1	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.02379244538503547	[398]	[498,361,278,317]	0	hSpCas9	negative selection	6133469
96115552	96115575	2	+	27260156	CADOES1	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.5651371598519193	[116]	[24,55,120,92]	-7	hSpCas9	negative selection	6197749
96115400	96115423	2	+	27260156	CADOES1	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.15873032710407187	[1170]	[875,915,1073,1038]	-3	hSpCas9	negative selection	6197750
96115891	96115914	2	-	27260156	CADOES1	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	-0.02322566194933673	[332]	[267,264,356,329]	0	hSpCas9	negative selection	6197751
96114817	96114840	2	+	27260156	EWS502	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.30222618940792745	[209]	[238,150,150,172]	-5	hSpCas9	negative selection	6254718
96115783	96115806	2	+	27260156	EWS502	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.0987460080501539	[437]	[395,577,579,436]	1	hSpCas9	negative selection	6254719
96115389	96115412	2	-	27260156	EWS502	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.03180908764436488	[398]	[440,291,538,380]	0	hSpCas9	negative selection	6254720
96115552	96115575	2	+	27260156	EWS502	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.4731754373283752	[116]	[79,35,138,106]	-7	hSpCas9	negative selection	6319000
96115400	96115423	2	+	27260156	EWS502	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.06789005418467897	[1170]	[1200,1504,1292,1191]	1	hSpCas9	negative selection	6319001
96115891	96115914	2	-	27260156	EWS502	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.03720704800698521	[332]	[205,471,349,437]	0	hSpCas9	negative selection	6319002
96114817	96114840	2	+	27260156	EW8	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.13175053763464994	[209]	[116,95,238,275]	2	hSpCas9	negative selection	6375969
96115783	96115806	2	+	27260156	EW8	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.1494014383193007	[437]	[386,388,183,349]	-3	hSpCas9	negative selection	6375970
96115389	96115412	2	-	27260156	EW8	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.028366340106524585	[398]	[435,262,324,254]	0	hSpCas9	negative selection	6375971
96115552	96115575	2	+	27260156	EW8	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.6929352810706644	[116]	[37,72,71,46]	-8	hSpCas9	negative selection	6440251
96115400	96115423	2	+	27260156	EW8	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.08251396820557755	[1170]	[1023,898,762,932]	-1	hSpCas9	negative selection	6440252
96115891	96115914	2	-	27260156	EW8	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.07066678198144494	[332]	[386,291,190,289]	1	hSpCas9	negative selection	6440253
96114817	96114840	2	+	27260156	CORL105	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.455062293285025	[209]	[141,178,248,156]	-7	hSpCas9	negative selection	6497220
96115783	96115806	2	+	27260156	CORL105	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.1476407562170447	[437]	[434,334,629,478]	-3	hSpCas9	negative selection	6497221
96115389	96115412	2	-	27260156	CORL105	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.06462765684820407	[398]	[506,502,373,551]	1	hSpCas9	negative selection	6497222
96115552	96115575	2	+	27260156	CORL105	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.8068320531607522	[116]	[46,61,76,125]	-8	hSpCas9	negative selection	6561502
96115400	96115423	2	+	27260156	CORL105	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.15000387936194026	[1170]	[1126,1035,1313,1475]	-3	hSpCas9	negative selection	6561503
96115891	96115914	2	-	27260156	CORL105	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	-0.08847032421513756	[332]	[499,281,285,391]	-2	hSpCas9	negative selection	6561504
96114817	96114840	2	+	27260156	HS294T	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.2688289312243386	[209]	[47,52,71,104]	-4	hSpCas9	negative selection	6618471
96115783	96115806	2	+	27260156	HS294T	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.03571594676557446	[437]	[185,137,145,193]	0	hSpCas9	negative selection	6618472
96115389	96115412	2	-	27260156	HS294T	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.36155371375743245	[398]	[143,234,144,286]	5	hSpCas9	negative selection	6618473
96115552	96115575	2	+	27260156	HS294T	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.33145194944339895	[116]	[72,18,25,19]	-5	hSpCas9	negative selection	6682753
96115400	96115423	2	+	27260156	HS294T	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.21449960057723394	[1170]	[398,497,444,819]	3	hSpCas9	negative selection	6682754
96115891	96115914	2	-	27260156	HS294T	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.2572097748954144	[332]	[143,90,139,260]	3	hSpCas9	negative selection	6682755
96114817	96114840	2	+	27260156	HCC44	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.8995544504999773	[209]	[175,38,134,174]	-8	hSpCas9	negative selection	6739722
96115783	96115806	2	+	27260156	HCC44	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.06893115133177129	[437]	[494,507,581,499]	1	hSpCas9	negative selection	6739723
96115389	96115412	2	-	27260156	HCC44	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.0005619918826601233	[398]	[532,355,465,469]	0	hSpCas9	negative selection	6739724
96115552	96115575	2	+	27260156	HCC44	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.6470187114527479	[116]	[45,83,140,72]	-7	hSpCas9	negative selection	6804004
96115400	96115423	2	+	27260156	HCC44	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.11591939740612323	[1170]	[1308,1247,1746,1491]	1	hSpCas9	negative selection	6804005
96115891	96115914	2	-	27260156	HCC44	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	-0.10990765802895297	[332]	[540,318,280,264]	-2	hSpCas9	negative selection	6804006
96114817	96114840	2	+	27260156	G402	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.30743392603736286	[209]	[427,167,136,127]	-4	hSpCas9	negative selection	6860973
96115783	96115806	2	+	27260156	G402	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.1764988082013264	[437]	[692,282,513,422]	-2	hSpCas9	negative selection	6860974
96115389	96115412	2	-	27260156	G402	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.12059071905861564	[398]	[1118,275,396,399]	1	hSpCas9	negative selection	6860975
96115552	96115575	2	+	27260156	G402	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.9110025132157089	[116]	[24,27,179,60]	-8	hSpCas9	negative selection	6925255
96115400	96115423	2	+	27260156	G402	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.02714517599974564	[1170]	[1597,1275,1530,1227]	0	hSpCas9	negative selection	6925256
96115891	96115914	2	-	27260156	G402	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.4916704341186688	[332]	[892,419,441,565]	6	hSpCas9	negative selection	6925257
96114817	96114840	2	+	27260156	L33	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.046253492578884225	[209]	[199,94,124,182]	-1	hSpCas9	negative selection	6982224
96115783	96115806	2	+	27260156	L33	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.08429205046855423	[437]	[490,146,265,377]	-2	hSpCas9	negative selection	6982225
96115389	96115412	2	-	27260156	L33	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.19579280915852196	[398]	[316,175,177,363]	-4	hSpCas9	negative selection	6982226
96115552	96115575	2	+	27260156	L33	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-1.4354651604266837	[116]	[54,21,23,25]	-9	hSpCas9	negative selection	7046506
96115400	96115423	2	+	27260156	L33	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.14761840659767334	[1170]	[1198,373,657,1065]	-3	hSpCas9	negative selection	7046507
96115891	96115914	2	-	27260156	L33	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.1301265594410373	[332]	[314,143,243,403]	3	hSpCas9	negative selection	7046508
96114817	96114840	2	+	27260156	K562	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.33250575165290586	[209]	[122,381,297,143]	4	hSpCas9	negative selection	7103475
96115783	96115806	2	+	27260156	K562	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.09682876782083463	[437]	[485,313,279,377]	-1	hSpCas9	negative selection	7103476
96115389	96115412	2	-	27260156	K562	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.29520717151212283	[398]	[204,241,372,319]	-4	hSpCas9	negative selection	7103477
96115552	96115575	2	+	27260156	K562	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-1.3988893675172247	[116]	[23,63,35,33]	-9	hSpCas9	negative selection	7167757
96115400	96115423	2	+	27260156	K562	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.2277148970049856	[1170]	[1192,956,483,934]	-3	hSpCas9	negative selection	7167758
96115891	96115914	2	-	27260156	K562	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.1751404959201981	[332]	[320,311,382,316]	2	hSpCas9	negative selection	7167759
96114817	96114840	2	+	27260156	HT29	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.19291843821525823	[209]	[332,213,215,145]	-4	hSpCas9	negative selection	7224726
96115783	96115806	2	+	27260156	HT29	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.024463981961760334	[437]	[652,588,360,504]	0	hSpCas9	negative selection	7224727
96115389	96115412	2	-	27260156	HT29	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.20294356276709982	[398]	[424,356,471,422]	-4	hSpCas9	negative selection	7224728
96115552	96115575	2	+	27260156	HT29	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	0.5995730658512326	[116]	[185,262,275,145]	9	hSpCas9	negative selection	7289008
96115400	96115423	2	+	27260156	HT29	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.2515468720453877	[1170]	[988,1481,1350,986]	-5	hSpCas9	negative selection	7289009
96115891	96115914	2	-	27260156	HT29	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.1779058127031371	[332]	[399,498,376,540]	3	hSpCas9	negative selection	7289010
96114817	96114840	2	+	27260156	MHHES1	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.17922125982237747	[209]	[329,381,239,157]	3	hSpCas9	negative selection	7345977
96115783	96115806	2	+	27260156	MHHES1	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.09209582102543531	[437]	[428,678,452,328]	-2	hSpCas9	negative selection	7345978
96115389	96115412	2	-	27260156	MHHES1	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.07108613384799783	[398]	[510,570,376,439]	1	hSpCas9	negative selection	7345979
96115552	96115575	2	+	27260156	MHHES1	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.7003472276701275	[116]	[47,104,76,88]	-8	hSpCas9	negative selection	7410259
96115400	96115423	2	+	27260156	MHHES1	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.38017006538495557	[1170]	[1035,1234,878,924]	-6	hSpCas9	negative selection	7410260
96115891	96115914	2	-	27260156	MHHES1	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.1786356781617841	[332]	[441,473,542,272]	3	hSpCas9	negative selection	7410261
96114817	96114840	2	+	27260156	MEWO	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.22076386419994498	[209]	[199,131,179]	-5	hSpCas9	negative selection	7467228
96115783	96115806	2	+	27260156	MEWO	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.17718282496236798	[437]	[730,406,303]	4	hSpCas9	negative selection	7467229
96115389	96115412	2	-	27260156	MEWO	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.07767566475140333	[398]	[240,404,392]	-2	hSpCas9	negative selection	7467230
96115552	96115575	2	+	27260156	MEWO	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.8771136674346289	[116]	[111,44,31]	-9	hSpCas9	negative selection	7531510
96115400	96115423	2	+	27260156	MEWO	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.05268522421283328	[1170]	[1287,939,985]	-1	hSpCas9	negative selection	7531511
96115891	96115914	2	-	27260156	MEWO	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	-0.11969556224853084	[332]	[271,346,237]	-3	hSpCas9	negative selection	7531512
96114817	96114840	2	+	27260156	LNCAPCLONEFGC	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.2703614719240045	[209]	[226,259,231,196]	4	hSpCas9	negative selection	7588479
96115783	96115806	2	+	27260156	LNCAPCLONEFGC	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.2673744314170201	[437]	[411,445,576,492]	4	hSpCas9	negative selection	7588480
96115389	96115412	2	-	27260156	LNCAPCLONEFGC	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.14169279103079	[398]	[339,377,383,492]	2	hSpCas9	negative selection	7588481
96115552	96115575	2	+	27260156	LNCAPCLONEFGC	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.8142285956631561	[116]	[51,81,54,49]	-8	hSpCas9	negative selection	7652761
96115400	96115423	2	+	27260156	LNCAPCLONEFGC	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.02880330811515308	[1170]	[1085,1044,1302,928]	0	hSpCas9	negative selection	7652762
96115891	96115914	2	-	27260156	LNCAPCLONEFGC	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.31650772329074084	[332]	[336,418,481,277]	5	hSpCas9	negative selection	7652763
96114817	96114840	2	+	27260156	PANC0327	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.5879827304901495	[209]	[245,269,270,332]	8	hSpCas9	negative selection	7709730
96115783	96115806	2	+	27260156	PANC0327	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.5397050094419724	[437]	[774,216,884,447]	7	hSpCas9	negative selection	7709731
96115389	96115412	2	-	27260156	PANC0327	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.5804799003102826	[398]	[418,774,428,455]	8	hSpCas9	negative selection	7709732
96115552	96115575	2	+	27260156	PANC0327	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.9607014161648872	[116]	[71,45,21,75]	-8	hSpCas9	negative selection	7774012
96115400	96115423	2	+	27260156	PANC0327	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.19168236680685946	[1170]	[1003,718,825,1125]	-3	hSpCas9	negative selection	7774013
96115891	96115914	2	-	27260156	PANC0327	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.06992795012011488	[332]	[527,285,306,141]	1	hSpCas9	negative selection	7774014
96114817	96114840	2	+	27260156	NCIH2009	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.57581808572189	[209]	[391,341,569]	7	hSpCas9	negative selection	7830981
96115783	96115806	2	+	27260156	NCIH2009	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.3658873182336732	[437]	[620,512,317]	-5	hSpCas9	negative selection	7830982
96115389	96115412	2	-	27260156	NCIH2009	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.14160676967425495	[398]	[731,557,577]	2	hSpCas9	negative selection	7830983
96115552	96115575	2	+	27260156	NCIH2009	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-1.5309818747417876	[116]	[83,57,32]	-9	hSpCas9	negative selection	7895263
96115400	96115423	2	+	27260156	NCIH2009	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.20554909438444224	[1170]	[1779,1276,1270]	-3	hSpCas9	negative selection	7895264
96115891	96115914	2	-	27260156	NCIH2009	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.2670912590623944	[332]	[687,559,455]	3	hSpCas9	negative selection	7895265
96114817	96114840	2	+	27260156	NCIH1373	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-1.432439571664048	[209]	[91,77,67,29]	-8	hSpCas9	negative selection	7952232
96115783	96115806	2	+	27260156	NCIH1373	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.7841364031653371	[437]	[278,306,190,95]	-7	hSpCas9	negative selection	7952233
96115389	96115412	2	-	27260156	NCIH1373	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.09278106400908948	[398]	[381,411,557,143]	0	hSpCas9	negative selection	7952234
96115552	96115575	2	+	27260156	NCIH1373	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-2.777353724864612	[116]	[4,23,21,5]	-9	hSpCas9	negative selection	8016514
96115400	96115423	2	+	27260156	NCIH1373	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	0.24160801493162198	[1170]	[1572,1094,1793,472]	2	hSpCas9	negative selection	8016515
96115891	96115914	2	-	27260156	NCIH1373	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.5031732544676304	[332]	[887,234,471,160]	5	hSpCas9	negative selection	8016516
96114817	96114840	2	+	27260156	PATU8902	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.6987429930703448	[209]	[174,336,103,115]	-6	hSpCas9	negative selection	8073483
96115783	96115806	2	+	27260156	PATU8902	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.9953486248953491	[437]	[259,269,191,559]	-7	hSpCas9	negative selection	8073484
96115389	96115412	2	-	27260156	PATU8902	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.305353706758412	[398]	[160,395,570,664]	-3	hSpCas9	negative selection	8073485
96115552	96115575	2	+	27260156	PATU8902	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	0.0510377131629014	[116]	[8,296,142,242]	0	hSpCas9	negative selection	8137765
96115400	96115423	2	+	27260156	PATU8902	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.3964632847312458	[1170]	[2107,1044,888,947]	-4	hSpCas9	negative selection	8137766
96115891	96115914	2	-	27260156	PATU8902	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.332459826861722	[332]	[1097,377,305,617]	3	hSpCas9	negative selection	8137767
96114817	96114840	2	+	27260156	PANC1	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.18696526929507762	[209]	[100,190,232,120]	-3	hSpCas9	negative selection	8194734
96115783	96115806	2	+	27260156	PANC1	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.08873458162727421	[437]	[257,795,403,245]	1	hSpCas9	negative selection	8194735
96115389	96115412	2	-	27260156	PANC1	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.09327410450385484	[398]	[334,280,504,175]	-1	hSpCas9	negative selection	8194736
96115552	96115575	2	+	27260156	PANC1	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-1.248040490417294	[116]	[74,39,15,36]	-9	hSpCas9	negative selection	8259016
96115400	96115423	2	+	27260156	PANC1	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.17036464677632024	[1170]	[808,1001,892,881]	-3	hSpCas9	negative selection	8259017
96115891	96115914	2	-	27260156	PANC1	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.5318260318064886	[332]	[349,535,318,459]	8	hSpCas9	negative selection	8259018
96114817	96114840	2	+	27260156	PANC0813	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.40998884161977167	[209]	[318,319,381,290]	6	hSpCas9	negative selection	8315985
96115783	96115806	2	+	27260156	PANC0813	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.01210149832875769	[437]	[718,448,437,455]	0	hSpCas9	negative selection	8315986
96115389	96115412	2	-	27260156	PANC0813	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.35851960236135866	[398]	[812,617,471,522]	6	hSpCas9	negative selection	8315987
96115552	96115575	2	+	27260156	PANC0813	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-1.53914499369048	[116]	[51,23,89,24]	-9	hSpCas9	negative selection	8380267
96115400	96115423	2	+	27260156	PANC0813	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.187115274422347	[1170]	[1436,1338,1051,1032]	-3	hSpCas9	negative selection	8380268
96115891	96115914	2	-	27260156	PANC0813	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.09927305536122027	[332]	[625,331,229,500]	1	hSpCas9	negative selection	8380269
96114817	96114840	2	+	27260156	RDES	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.22098261904116567	[209]	[137,209,290,200]	-4	hSpCas9	negative selection	8437236
96115783	96115806	2	+	27260156	RDES	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.1074377146765865	[437]	[424,481,681,612]	1	hSpCas9	negative selection	8437237
96115389	96115412	2	-	27260156	RDES	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.10562547380690587	[398]	[421,449,609,502]	1	hSpCas9	negative selection	8437238
96115552	96115575	2	+	27260156	RDES	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.8093489307160722	[116]	[43,84,117,63]	-8	hSpCas9	negative selection	8501518
96115400	96115423	2	+	27260156	RDES	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.019138210579308534	[1170]	[1149,1090,1458,1697]	0	hSpCas9	negative selection	8501519
96115891	96115914	2	-	27260156	RDES	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.22669921791118608	[332]	[407,302,517,597]	3	hSpCas9	negative selection	8501520
96114817	96114840	2	+	27260156	PC3	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.05919488408740725	[209]	[100,168,303,303]	-1	hSpCas9	negative selection	8558487
96115783	96115806	2	+	27260156	PC3	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.4238287788345117	[437]	[385,687,738,610]	8	hSpCas9	negative selection	8558488
96115389	96115412	2	-	27260156	PC3	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.14862414945015676	[398]	[125,413,579,483]	-3	hSpCas9	negative selection	8558489
96115552	96115575	2	+	27260156	PC3	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-1.0107068761022622	[116]	[49,44,101,47]	-9	hSpCas9	negative selection	8622769
96115400	96115423	2	+	27260156	PC3	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.10227462547198152	[1170]	[790,1071,1700,1030]	-2	hSpCas9	negative selection	8622770
96115891	96115914	2	-	27260156	PC3	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.02873238911362952	[332]	[170,354,596,378]	0	hSpCas9	negative selection	8622771
96114817	96114840	2	+	27260156	PATU8988T	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.02329313377149722	[209]	[150,332,181,167]	0	hSpCas9	negative selection	8679738
96115783	96115806	2	+	27260156	PATU8988T	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.07612953522178692	[437]	[281,534,584,383]	1	hSpCas9	negative selection	8679739
96115389	96115412	2	-	27260156	PATU8988T	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.13444518651492013	[398]	[413,370,377,233]	-2	hSpCas9	negative selection	8679740
96115552	96115575	2	+	27260156	PATU8988T	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.37660257231238603	[116]	[59,218,43,33]	-6	hSpCas9	negative selection	8744020
96115400	96115423	2	+	27260156	PATU8988T	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.006359987971179315	[1170]	[1105,1167,1198,1027]	0	hSpCas9	negative selection	8744021
96115891	96115914	2	-	27260156	PATU8988T	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.21286519997131031	[332]	[288,455,325,433]	3	hSpCas9	negative selection	8744022
96114817	96114840	2	+	27260156	T47D	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.04240439025028708	[209]	[247,229,212,260]	-1	hSpCas9	negative selection	8800989
96115783	96115806	2	+	27260156	T47D	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.3045108411172789	[437]	[641,567,564,755]	6	hSpCas9	negative selection	8800990
96115389	96115412	2	-	27260156	T47D	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.08581069002899086	[398]	[413,393,516,428]	-2	hSpCas9	negative selection	8800991
96115552	96115575	2	+	27260156	T47D	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.4341979274746097	[116]	[143,76,63,121]	-7	hSpCas9	negative selection	8865271
96115400	96115423	2	+	27260156	T47D	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.26895902866693877	[1170]	[1205,903,1258,1178]	-5	hSpCas9	negative selection	8865272
96115891	96115914	2	-	27260156	T47D	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	-0.13831105859601112	[332]	[361,311,341,398]	-3	hSpCas9	negative selection	8865273
96114817	96114840	2	+	27260156	SU8686	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.41949334242112224	[209]	[118,159,154,197]	-6	hSpCas9	negative selection	8922240
96115783	96115806	2	+	27260156	SU8686	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.25394108202440974	[437]	[322,293,379,491]	-4	hSpCas9	negative selection	8922241
96115389	96115412	2	-	27260156	SU8686	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.21231957573727073	[398]	[358,482,428,586]	3	hSpCas9	negative selection	8922242
96115552	96115575	2	+	27260156	SU8686	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.45366742356754	[116]	[35,39,126,159]	-6	hSpCas9	negative selection	8986522
96115400	96115423	2	+	27260156	SU8686	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.33483283020200494	[1170]	[868,789,1028,1030]	-5	hSpCas9	negative selection	8986523
96115891	96115914	2	-	27260156	SU8686	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.30812829344648085	[332]	[377,386,421,459]	5	hSpCas9	negative selection	8986524
96114817	96114840	2	+	27260156	SKES1	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.3069140077294721	[209]	[190,177,89,215]	-6	hSpCas9	negative selection	9043491
96115783	96115806	2	+	27260156	SKES1	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.3656940755604686	[437]	[540,574,541,583]	7	hSpCas9	negative selection	9043492
96115389	96115412	2	-	27260156	SKES1	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.1098942684565864	[398]	[440,427,498,354]	2	hSpCas9	negative selection	9043493
96115552	96115575	2	+	27260156	SKES1	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.4302824857119729	[116]	[87,102,91,66]	-7	hSpCas9	negative selection	9107773
96115400	96115423	2	+	27260156	SKES1	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.07029351109358584	[1170]	[1193,1248,1133,912]	-1	hSpCas9	negative selection	9107774
96115891	96115914	2	-	27260156	SKES1	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.21933049235699503	[332]	[473,322,368,381]	5	hSpCas9	negative selection	9107775
96114817	96114840	2	+	27260156	TOV112D	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.1957362846622943	[209]	[179,204,307,49]	-4	hSpCas9	negative selection	9164742
96115783	96115806	2	+	27260156	TOV112D	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.09565500498314214	[437]	[524,682,374,351]	1	hSpCas9	negative selection	9164743
96115389	96115412	2	-	27260156	TOV112D	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.18132353523413478	[398]	[181,346,496,366]	-4	hSpCas9	negative selection	9164744
96115552	96115575	2	+	27260156	TOV112D	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-1.4203467693784306	[116]	[34,3,98,26]	-9	hSpCas9	negative selection	9229024
96115400	96115423	2	+	27260156	TOV112D	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.2521004051420599	[1170]	[1038,1223,936,805]	-5	hSpCas9	negative selection	9229025
96115891	96115914	2	-	27260156	TOV112D	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.47996098853634866	[332]	[513,400,533,400]	8	hSpCas9	negative selection	9229026
96114817	96114840	2	+	27260156	TC71	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	-0.07021856422188977	[209]	[104,274,188,296]	-2	hSpCas9	negative selection	9285993
96115783	96115806	2	+	27260156	TC71	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	-0.06516557677042217	[437]	[545,443,365,438]	-2	hSpCas9	negative selection	9285994
96115389	96115412	2	-	27260156	TC71	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	-0.2150621885402039	[398]	[394,411,314,351]	-5	hSpCas9	negative selection	9285995
96115552	96115575	2	+	27260156	TC71	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.5159456303979701	[116]	[63,70,107,108]	-8	hSpCas9	negative selection	9350275
96115400	96115423	2	+	27260156	TC71	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.17869517826652226	[1170]	[1223,1055,980,1180]	-5	hSpCas9	negative selection	9350276
96115891	96115914	2	-	27260156	TC71	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.22499765788312442	[332]	[354,352,352,623]	5	hSpCas9	negative selection	9350277
96114817	96114840	2	+	27260156	TC32	viability	ACGGGCGGCACAGGATCCTCCGG	ADRA2B	ENSG00000274286	0.36601363883173976	[209]	[258,170,422,206]	6	hSpCas9	negative selection	9407244
96115783	96115806	2	+	27260156	TC32	viability	TGGAGTTGTACTCCAGCGCGCGG	ADRA2B	ENSG00000274286	0.16106449193751196	[437]	[410,388,562,502]	3	hSpCas9	negative selection	9407245
96115389	96115412	2	-	27260156	TC32	viability	AACGGACACTCGAAGTCCACTGG	ADRA2B	ENSG00000274286	0.16076088537582994	[398]	[432,300,598,390]	3	hSpCas9	negative selection	9407246
96115552	96115575	2	+	27260156	TC32	viability	TGGCGATCAGGTAGATGCGCAGG	ADRA2B	ENSG00000274286	-0.008783033113191951	[116]	[125,102,133,68]	0	hSpCas9	negative selection	9471526
96115400	96115423	2	+	27260156	TC32	viability	CGAGTGTCCGTTGACCTCTCTGG	ADRA2B	ENSG00000274286	-0.142735351478386	[1170]	[949,701,1262,1187]	-3	hSpCas9	negative selection	9471527
96115891	96115914	2	-	27260156	TC32	viability	CTTCCGGCGCACGTGGTGCGAGG	ADRA2B	ENSG00000274286	0.20706733770099983	[332]	[313,201,578,438]	4	hSpCas9	negative selection	9471528
96114829	96114852	2	+	27869803	HPAFII	viability after 27 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.5885881789881132	[187]	[44,82,NaN]	-4	hSpCas9	negative selection	9576176
96115642	96115665	2	+	27869803	HPAFII	viability after 27 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.5148420711864479	[227]	[257,98,NaN]	4	hSpCas9	negative selection	9576177
96115642	96115665	2	-	27869803	HPAFII	viability after 27 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.26923426531564765	[575]	[259,243,NaN]	-2	hSpCas9	negative selection	9576178
96115753	96115776	2	+	27869803	HPAFII	viability after 27 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.024198644544323862	[251]	[53,201,NaN]	0	hSpCas9	negative selection	9576179
96115754	96115777	2	+	27869803	HPAFII	viability after 27 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	1.5459110387458883	[78]	[15,208,NaN]	9	hSpCas9	negative selection	9576180
96116026	96116049	2	+	27869803	HPAFII	viability after 27 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	2.197734899539015	[48]	[19,199,NaN]	9	hSpCas9	negative selection	9576181
96114829	96114852	2	+	27869803	HPAFII	viability after 15 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.09804800507746958	[187]	[263,141,NaN]	-1	hSpCas9	negative selection	9658625
96115642	96115665	2	+	27869803	HPAFII	viability after 15 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.2661853260301333	[227]	[528,148,NaN]	3	hSpCas9	negative selection	9658626
96115642	96115665	2	-	27869803	HPAFII	viability after 15 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.13319143479471474	[575]	[762,440,NaN]	-1	hSpCas9	negative selection	9658627
96115753	96115776	2	+	27869803	HPAFII	viability after 15 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	-0.5010788861523233	[251]	[162,208,NaN]	-5	hSpCas9	negative selection	9658628
96115754	96115777	2	+	27869803	HPAFII	viability after 15 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	0.9005035880440343	[78]	[65,215,NaN]	8	hSpCas9	negative selection	9658629
96116026	96116049	2	+	27869803	HPAFII	viability after 15 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	1.1796849128932885	[48]	[48,162,NaN]	9	hSpCas9	negative selection	9658630
96114829	96114852	2	+	27869803	ASPC1	viability after 36 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.6802403575108616	[340]	[76,69,74]	-6	hSpCas9	negative selection	9741074
96115642	96115665	2	+	27869803	ASPC1	viability after 36 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.25044572480465277	[570]	[221,448,76]	2	hSpCas9	negative selection	9741075
96115642	96115665	2	-	27869803	ASPC1	viability after 36 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.43013625895954066	[1098]	[541,784,280]	4	hSpCas9	negative selection	9741076
96115753	96115776	2	+	27869803	ASPC1	viability after 36 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	-0.4343047981077694	[655]	[236,58,207]	-4	hSpCas9	negative selection	9741077
96115754	96115777	2	+	27869803	ASPC1	viability after 36 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	0.41209624840165704	[173]	[38,118,78]	4	hSpCas9	negative selection	9741078
96116026	96116049	2	+	27869803	ASPC1	viability after 36 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	-1.1076012203351624	[158]	[5,0,58]	-8	hSpCas9	negative selection	9741079
96114829	96114852	2	+	27869803	PATU8988S	viability after 35 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.46835265895841827	[325]	[50,138,NaN]	-5	hSpCas9	negative selection	9823523
96115642	96115665	2	+	27869803	PATU8988S	viability after 35 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.47507013722291735	[515]	[229,347,NaN]	5	hSpCas9	negative selection	9823524
96115642	96115665	2	-	27869803	PATU8988S	viability after 35 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.2904519212156942	[880]	[414,452,NaN]	3	hSpCas9	negative selection	9823525
96115753	96115776	2	+	27869803	PATU8988S	viability after 35 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	-0.35374239168327987	[423]	[191,74,NaN]	-4	hSpCas9	negative selection	9823526
96115754	96115777	2	+	27869803	PATU8988S	viability after 35 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	0.6266955470092851	[193]	[181,58,NaN]	7	hSpCas9	negative selection	9823527
96116026	96116049	2	+	27869803	PATU8988S	viability after 35 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	-1.227549328372184	[118]	[5,34,NaN]	-8	hSpCas9	negative selection	9823528
96114829	96114852	2	+	27869803	PATU8988S	viability after 31 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.18842427005760554	[325]	[88,145,NaN]	-2	hSpCas9	negative selection	9905972
96115642	96115665	2	+	27869803	PATU8988S	viability after 31 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	-0.11976811673626858	[515]	[191,185,NaN]	-1	hSpCas9	negative selection	9905973
96115642	96115665	2	-	27869803	PATU8988S	viability after 31 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.3139924242484139	[880]	[375,513,NaN]	4	hSpCas9	negative selection	9905974
96115753	96115776	2	+	27869803	PATU8988S	viability after 31 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	-0.24158192633480574	[423]	[142,142,NaN]	-3	hSpCas9	negative selection	9905975
96115754	96115777	2	+	27869803	PATU8988S	viability after 31 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	0.8844340090445956	[193]	[155,125,NaN]	8	hSpCas9	negative selection	9905976
96116026	96116049	2	+	27869803	PATU8988S	viability after 31 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	-0.3699918427211504	[118]	[19,57,NaN]	-4	hSpCas9	negative selection	9905977
96114829	96114852	2	+	27869803	HPAFII	viability after 35 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.1495546800328751	[187]	[42,133,NaN]	-1	hSpCas9	negative selection	9988421
96115642	96115665	2	+	27869803	HPAFII	viability after 35 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	0.9251828557971624	[227]	[229,206,NaN]	6	hSpCas9	negative selection	9988422
96115642	96115665	2	-	27869803	HPAFII	viability after 35 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.21696855351612543	[575]	[297,384,NaN]	1	hSpCas9	negative selection	9988423
96115753	96115776	2	+	27869803	HPAFII	viability after 35 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.4006856273378679	[251]	[55,294,NaN]	2	hSpCas9	negative selection	9988424
96115754	96115777	2	+	27869803	HPAFII	viability after 35 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	2.1033785500399333	[78]	[2,361,NaN]	9	hSpCas9	negative selection	9988425
96116026	96116049	2	+	27869803	HPAFII	viability after 35 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	2.330011856416982	[48]	[48,209,NaN]	9	hSpCas9	negative selection	9988426
96114829	96114852	2	+	27869803	HPAFII	viability after 31 days	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.6741716623297505	[187]	[12,123,NaN]	-4	hSpCas9	negative selection	10070870
96115642	96115665	2	+	27869803	HPAFII	viability after 31 days	CCTCCTGGTTGAGCTTGCACTGG	ADRA2B	ENSG00000274286	1.0936534850433177	[227]	[352,185,NaN]	7	hSpCas9	negative selection	10070871
96115642	96115665	2	-	27869803	HPAFII	viability after 31 days	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.4091991035988205	[575]	[252,232,NaN]	-3	hSpCas9	negative selection	10070872
96115753	96115776	2	+	27869803	HPAFII	viability after 31 days	TGATGCACTTGATGCGGCGCGGG	ADRA2B	ENSG00000274286	0.27857659184563366	[251]	[60,291,NaN]	2	hSpCas9	negative selection	10070873
96115754	96115777	2	+	27869803	HPAFII	viability after 31 days	GATGCACTTGATGCGGCGCGGGG	ADRA2B	ENSG00000274286	1.7996521242259171	[78]	[16,303,NaN]	9	hSpCas9	negative selection	10070874
96116026	96116049	2	+	27869803	HPAFII	viability after 31 days	AGCGGCTGGTCAACACAGCCAGG	ADRA2B	ENSG00000274286	1.9156288817943365	[48]	[19,194,NaN]	9	hSpCas9	negative selection	10070875
96114829	96114852	2	+	28162770	P31FUJ	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.6530267756663102	[91]	[169]	7	hSpCas9	negative selection	10107714
96116098	96116121	2	-	28162770	P31FUJ	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	0.016717394944933517	[142]	[169]	0	hSpCas9	negative selection	10107715
96115964	96115987	2	+	28162770	P31FUJ	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-0.750650509276998	[125]	[87]	-5	hSpCas9	negative selection	10107716
96115709	96115732	2	+	28162770	P31FUJ	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	-0.7022874877155987	[71]	[51]	-5	hSpCas9	negative selection	10107717
96115642	96115665	2	-	28162770	P31FUJ	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.3925258930058764	[228]	[204]	-4	hSpCas9	negative selection	10107718
96115533	96115556	2	-	28162770	P31FUJ	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	0.7514304797273046	[137]	[272]	8	hSpCas9	negative selection	10107719
96115246	96115269	2	-	28162770	P31FUJ	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-5.040157126471982	[139]	[4]	-9	hSpCas9	negative selection	10107720
96115030	96115053	2	-	28162770	P31FUJ	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	0.08353042757946416	[154]	[192]	0	hSpCas9	negative selection	10107721
96114917	96114940	2	+	28162770	P31FUJ	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.4957756042591086	[206]	[342]	5	hSpCas9	negative selection	10107722
96116122	96116145	2	+	28162770	P31FUJ	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.40595037963610947	[622]	[969]	4	hSpCas9	negative selection	10107723
96114829	96114852	2	+	28162770	TF1	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10277080
96116098	96116121	2	-	28162770	TF1	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10277081
96115964	96115987	2	+	28162770	TF1	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10277082
96115709	96115732	2	+	28162770	TF1	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10277083
96115642	96115665	2	-	28162770	TF1	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10277084
96115533	96115556	2	-	28162770	TF1	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	NaN	[NaN]	[159]	1	hSpCas9	negative selection	10277085
96115246	96115269	2	-	28162770	TF1	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10277086
96115030	96115053	2	-	28162770	TF1	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10277087
96114917	96114940	2	+	28162770	TF1	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10277088
96116122	96116145	2	+	28162770	TF1	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	NaN	[NaN]	[599]	1	hSpCas9	negative selection	10277089
96114829	96114852	2	+	28162770	SKM1	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-1.036126503374853	[28]	[24]	-6	hSpCas9	negative selection	10446446
96116098	96116121	2	-	28162770	SKM1	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	-0.2508449968258796	[34]	[51]	-2	hSpCas9	negative selection	10446447
96115964	96115987	2	+	28162770	SKM1	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-1.6134150762105879	[44]	[25]	-8	hSpCas9	negative selection	10446448
96115709	96115732	2	+	28162770	SKM1	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	-0.9824663702152518	[18]	[16]	-6	hSpCas9	negative selection	10446449
96115642	96115665	2	-	28162770	SKM1	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.17799830197799435	[53]	[107]	1	hSpCas9	negative selection	10446450
96115533	96115556	2	-	28162770	SKM1	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	-0.20789285164133287	[48]	[74]	-2	hSpCas9	negative selection	10446451
96115246	96115269	2	-	28162770	SKM1	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-2.880895387075574	[24]	[5]	-9	hSpCas9	negative selection	10446452
96115030	96115053	2	-	28162770	SKM1	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	0.005161705115778847	[30]	[54]	0	hSpCas9	negative selection	10446453
96114917	96114940	2	+	28162770	SKM1	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.48056107199842585	[74]	[184]	4	hSpCas9	negative selection	10446454
96116122	96116145	2	+	28162770	SKM1	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.4185588460133671	[123]	[292]	4	hSpCas9	negative selection	10446455
96114829	96114852	2	+	28162770	SKM1	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-1.036126503374853	[28]	[24]	-6	hSpCas9	negative selection	10615812
96116098	96116121	2	-	28162770	SKM1	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	-0.2508449968258796	[34]	[51]	-2	hSpCas9	negative selection	10615813
96115964	96115987	2	+	28162770	SKM1	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-1.6134150762105879	[44]	[25]	-8	hSpCas9	negative selection	10615814
96115709	96115732	2	+	28162770	SKM1	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	-0.9824663702152518	[18]	[16]	-6	hSpCas9	negative selection	10615815
96115642	96115665	2	-	28162770	SKM1	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.17799830197799435	[53]	[107]	1	hSpCas9	negative selection	10615816
96115533	96115556	2	-	28162770	SKM1	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	-0.20789285164133287	[48]	[74]	-2	hSpCas9	negative selection	10615817
96115246	96115269	2	-	28162770	SKM1	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-2.880895387075574	[24]	[5]	-9	hSpCas9	negative selection	10615818
96115030	96115053	2	-	28162770	SKM1	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	0.005161705115778847	[30]	[54]	0	hSpCas9	negative selection	10615819
96114917	96114940	2	+	28162770	SKM1	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.48056107199842585	[74]	[184]	4	hSpCas9	negative selection	10615820
96116122	96116145	2	+	28162770	SKM1	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.4185588460133671	[123]	[292]	4	hSpCas9	negative selection	10615821
96114829	96114852	2	+	28162770	PL21	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-0.8263325968718709	[109]	[26]	-5	hSpCas9	negative selection	10785178
96116098	96116121	2	-	28162770	PL21	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	0.5570741592045958	[113]	[72]	5	hSpCas9	negative selection	10785179
96115964	96115987	2	+	28162770	PL21	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-2.4243512504184737	[110]	[8]	-9	hSpCas9	negative selection	10785180
96115709	96115732	2	+	28162770	PL21	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	0.7103343468085042	[65]	[46]	6	hSpCas9	negative selection	10785181
96115642	96115665	2	-	28162770	PL21	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.03291973189898392	[180]	[76]	0	hSpCas9	negative selection	10785182
96115533	96115556	2	-	28162770	PL21	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	0.8015902379990452	[144]	[109]	7	hSpCas9	negative selection	10785183
96115246	96115269	2	-	28162770	PL21	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-5.58122009903534	[109]	[0]	-9	hSpCas9	negative selection	10785184
96115030	96115053	2	-	28162770	PL21	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	0.5733569380735368	[104]	[67]	5	hSpCas9	negative selection	10785185
96114917	96114940	2	+	28162770	PL21	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	-0.315449183191174	[202]	[70]	-2	hSpCas9	negative selection	10785186
96116122	96116145	2	+	28162770	PL21	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.6407122058753014	[419]	[284]	5	hSpCas9	negative selection	10785187
96114829	96114852	2	+	28162770	P31FUJ	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.6530267756663102	[91]	[169]	7	hSpCas9	negative selection	10954544
96116098	96116121	2	-	28162770	P31FUJ	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	0.016717394944933517	[142]	[169]	0	hSpCas9	negative selection	10954545
96115964	96115987	2	+	28162770	P31FUJ	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-0.750650509276998	[125]	[87]	-5	hSpCas9	negative selection	10954546
96115709	96115732	2	+	28162770	P31FUJ	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	-0.7022874877155987	[71]	[51]	-5	hSpCas9	negative selection	10954547
96115642	96115665	2	-	28162770	P31FUJ	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	-0.3925258930058764	[228]	[204]	-4	hSpCas9	negative selection	10954548
96115533	96115556	2	-	28162770	P31FUJ	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	0.7514304797273046	[137]	[272]	8	hSpCas9	negative selection	10954549
96115246	96115269	2	-	28162770	P31FUJ	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-5.040157126471982	[139]	[4]	-9	hSpCas9	negative selection	10954550
96115030	96115053	2	-	28162770	P31FUJ	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	0.08353042757946416	[154]	[192]	0	hSpCas9	negative selection	10954551
96114917	96114940	2	+	28162770	P31FUJ	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.4957756042591086	[206]	[342]	5	hSpCas9	negative selection	10954552
96116122	96116145	2	+	28162770	P31FUJ	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.40595037963610947	[622]	[969]	4	hSpCas9	negative selection	10954553
96114829	96114852	2	+	28162770	OCIAML5	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	1.582336253281778	[36]	[199]	9	hSpCas9	negative selection	11123910
96116098	96116121	2	-	28162770	OCIAML5	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	-0.43375393955229213	[109]	[146]	-3	hSpCas9	negative selection	11123911
96115964	96115987	2	+	28162770	OCIAML5	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-0.156921152392418	[62]	[101]	-1	hSpCas9	negative selection	11123912
96115709	96115732	2	+	28162770	OCIAML5	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	0.7127180479195288	[23]	[70]	6	hSpCas9	negative selection	11123913
96115642	96115665	2	-	28162770	OCIAML5	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.24901955425031735	[123]	[265]	2	hSpCas9	negative selection	11123914
96115533	96115556	2	-	28162770	OCIAML5	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	0.21104347299064122	[122]	[256]	1	hSpCas9	negative selection	11123915
96115246	96115269	2	-	28162770	OCIAML5	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-4.772632103369592	[105]	[6]	-9	hSpCas9	negative selection	11123916
96115030	96115053	2	-	28162770	OCIAML5	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	-0.40984424225892274	[91]	[124]	-3	hSpCas9	negative selection	11123917
96114917	96114940	2	+	28162770	OCIAML5	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.13522237738644907	[113]	[225]	1	hSpCas9	negative selection	11123918
96116122	96116145	2	+	28162770	OCIAML5	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	-0.08677225363929653	[352]	[599]	0	hSpCas9	negative selection	11123919
96114829	96114852	2	+	28162770	EOL1	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.11096089580141566	[173]	[98]	1	hSpCas9	negative selection	11293276
96116098	96116121	2	-	28162770	EOL1	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	0.664903954937515	[169]	[141]	6	hSpCas9	negative selection	11293277
96115964	96115987	2	+	28162770	EOL1	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-0.6749142988457366	[199]	[65]	-5	hSpCas9	negative selection	11293278
96115709	96115732	2	+	28162770	EOL1	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	-0.5140252421690983	[102]	[37]	-4	hSpCas9	negative selection	11293279
96115642	96115665	2	-	28162770	EOL1	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.9660399004889979	[376]	[387]	8	hSpCas9	negative selection	11293280
96115533	96115556	2	-	28162770	EOL1	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	-0.09764797454366148	[261]	[128]	0	hSpCas9	negative selection	11293281
96115246	96115269	2	-	28162770	EOL1	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-4.060345336039257	[94]	[2]	-9	hSpCas9	negative selection	11293282
96115030	96115053	2	-	28162770	EOL1	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	2.0419047222086935	[176]	[383]	9	hSpCas9	negative selection	11293283
96114917	96114940	2	+	28162770	EOL1	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	-1.2222936167587364	[309]	[69]	-7	hSpCas9	negative selection	11293284
96116122	96116145	2	+	28162770	EOL1	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	1.1904912566807255	[577]	[694]	8	hSpCas9	negative selection	11293285
96114829	96114852	2	+	28162770	MOLM13	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	1.2531505327515662	[140]	[242]	8	hSpCas9	negative selection	11462642
96116098	96116121	2	-	28162770	MOLM13	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	0.5378519397121462	[160]	[168]	4	hSpCas9	negative selection	11462643
96115964	96115987	2	+	28162770	MOLM13	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-0.08604622355595293	[137]	[93]	0	hSpCas9	negative selection	11462644
96115709	96115732	2	+	28162770	MOLM13	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	1.5510306168448245	[58]	[124]	9	hSpCas9	negative selection	11462645
96115642	96115665	2	-	28162770	MOLM13	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.5960234001218342	[322]	[352]	4	hSpCas9	negative selection	11462646
96115533	96115556	2	-	28162770	MOLM13	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	-1.3113419395986372	[253]	[73]	-6	hSpCas9	negative selection	11462647
96115246	96115269	2	-	28162770	MOLM13	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-5.94996313334132	[170]	[1]	-9	hSpCas9	negative selection	11462648
96115030	96115053	2	-	28162770	MOLM13	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	-1.0968952372389473	[212]	[71]	-5	hSpCas9	negative selection	11462649
96114917	96114940	2	+	28162770	MOLM13	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	-1.2402721839742492	[280]	[85]	-6	hSpCas9	negative selection	11462650
96116122	96116145	2	+	28162770	MOLM13	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.4961784259760027	[504]	[514]	3	hSpCas9	negative selection	11462651
96114829	96114852	2	+	28162770	HEL	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.9646669268877192	[83]	[104]	8	hSpCas9	negative selection	11632008
96116098	96116121	2	-	28162770	HEL	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	-0.12056090997931168	[128]	[75]	-1	hSpCas9	negative selection	11632009
96115964	96115987	2	+	28162770	HEL	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-0.49015543849698817	[124]	[56]	-3	hSpCas9	negative selection	11632010
96115709	96115732	2	+	28162770	HEL	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	1.2836577386955286	[58]	[91]	9	hSpCas9	negative selection	11632011
96115642	96115665	2	-	28162770	HEL	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.5100362945142433	[329]	[300]	4	hSpCas9	negative selection	11632012
96115533	96115556	2	-	28162770	HEL	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	0.8984684372109175	[164]	[196]	7	hSpCas9	negative selection	11632013
96115246	96115269	2	-	28162770	HEL	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-6.345945854771809	[126]	[0]	-9	hSpCas9	negative selection	11632014
96115030	96115053	2	-	28162770	HEL	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	-0.9422236687207993	[173]	[57]	-5	hSpCas9	negative selection	11632015
96114917	96114940	2	+	28162770	HEL	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.02862998561968423	[224]	[146]	0	hSpCas9	negative selection	11632016
96116122	96116145	2	+	28162770	HEL	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	-0.47221233435052756	[456]	[210]	-3	hSpCas9	negative selection	11632017
96114829	96114852	2	+	28162770	MV411	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.6972404682222957	[81]	[111]	6	hSpCas9	negative selection	11801374
96116098	96116121	2	-	28162770	MV411	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	-0.2101456434621532	[194]	[141]	-2	hSpCas9	negative selection	11801375
96115964	96115987	2	+	28162770	MV411	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	-0.24011244828043615	[135]	[96]	-2	hSpCas9	negative selection	11801376
96115709	96115732	2	+	28162770	MV411	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	-0.1462262977035016	[66]	[50]	-1	hSpCas9	negative selection	11801377
96115642	96115665	2	-	28162770	MV411	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	1.1623560498930072	[226]	[427]	8	hSpCas9	negative selection	11801378
96115533	96115556	2	-	28162770	MV411	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	1.7178402872410756	[130]	[362]	9	hSpCas9	negative selection	11801379
96115246	96115269	2	-	28162770	MV411	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-6.5980525001616	[114]	[0]	-9	hSpCas9	negative selection	11801380
96115030	96115053	2	-	28162770	MV411	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	-0.4397750081863313	[94]	[58]	-3	hSpCas9	negative selection	11801381
96114917	96114940	2	+	28162770	MV411	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	-0.2907766907469017	[166]	[114]	-2	hSpCas9	negative selection	11801382
96116122	96116145	2	+	28162770	MV411	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.36535175364854444	[363]	[394]	3	hSpCas9	negative selection	11801383
96114829	96114852	2	+	28162770	MONOMAC1	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.5191701869398548	[41]	[68]	5	hSpCas9	negative selection	11970740
96116098	96116121	2	-	28162770	MONOMAC1	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	-0.2804528552471913	[88]	[83]	-2	hSpCas9	negative selection	11970741
96115964	96115987	2	+	28162770	MONOMAC1	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	0.1873038549963738	[94]	[123]	2	hSpCas9	negative selection	11970742
96115709	96115732	2	+	28162770	MONOMAC1	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	0.09246977013543134	[35]	[43]	0	hSpCas9	negative selection	11970743
96115642	96115665	2	-	28162770	MONOMAC1	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.46906241638700796	[120]	[191]	4	hSpCas9	negative selection	11970744
96115533	96115556	2	-	28162770	MONOMAC1	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	0.0009025305523552851	[101]	[116]	0	hSpCas9	negative selection	11970745
96115246	96115269	2	-	28162770	MONOMAC1	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-1.8850928407448133	[57]	[17]	-8	hSpCas9	negative selection	11970746
96115030	96115053	2	-	28162770	MONOMAC1	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	-0.3414267563947285	[62]	[56]	-3	hSpCas9	negative selection	11970747
96114917	96114940	2	+	28162770	MONOMAC1	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	-0.2884598748231485	[113]	[106]	-3	hSpCas9	negative selection	11970748
96116122	96116145	2	+	28162770	MONOMAC1	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	-0.22730428672835035	[288]	[282]	-2	hSpCas9	negative selection	11970749
96114829	96114852	2	+	28162770	OCIAML2	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	0.690833597451955	[18]	[169]	6	hSpCas9	negative selection	12140106
96116098	96116121	2	-	28162770	OCIAML2	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	0.7131673507817087	[22]	[208]	7	hSpCas9	negative selection	12140107
96115964	96115987	2	+	28162770	OCIAML2	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	0.3633602233189096	[22]	[163]	3	hSpCas9	negative selection	12140108
96115709	96115732	2	+	28162770	OCIAML2	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	0.7237482199246901	[12]	[118]	7	hSpCas9	negative selection	12140109
96115642	96115665	2	-	28162770	OCIAML2	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	1.0033013630902512	[26]	[299]	8	hSpCas9	negative selection	12140110
96115533	96115556	2	-	28162770	OCIAML2	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	0.4658050459803725	[28]	[221]	4	hSpCas9	negative selection	12140111
96115246	96115269	2	-	28162770	OCIAML2	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-3.750737744434897	[16]	[6]	-9	hSpCas9	negative selection	12140112
96115030	96115053	2	-	28162770	OCIAML2	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	-1.2277733013459977	[29]	[70]	-7	hSpCas9	negative selection	12140113
96114917	96114940	2	+	28162770	OCIAML2	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.5928731170639967	[24]	[208]	6	hSpCas9	negative selection	12140114
96116122	96116145	2	+	28162770	OCIAML2	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	1.0819111977866174	[44]	[527]	8	hSpCas9	negative selection	12140115
96114829	96114852	2	+	28162770	OCIAML3	viability	GGATCCTCCGGAAGGCACGGCGG	ADRA2B	ENSG00000274286	-1.0731754770227226	[22]	[32]	-6	hSpCas9	negative selection	12309472
96116098	96116121	2	-	28162770	OCIAML3	viability	GGCCACAGCGGCCATAGCGGCGG	ADRA2B	ENSG00000274286	-0.05967121267297493	[28]	[83]	0	hSpCas9	negative selection	12309473
96115964	96115987	2	+	28162770	OCIAML3	viability	GGCCACCAGGATGTCGGCGGCGG	ADRA2B	ENSG00000274286	0.8162763289840461	[37]	[201]	7	hSpCas9	negative selection	12309474
96115709	96115732	2	+	28162770	OCIAML3	viability	GGGCGGCAGCGAGATGACGGCGG	ADRA2B	ENSG00000274286	-1.3183731977107358	[18]	[22]	-7	hSpCas9	negative selection	12309475
96115642	96115665	2	-	28162770	OCIAML3	viability	CCAGTGCAAGCTCAACCAGGAGG	ADRA2B	ENSG00000274286	0.34709867062226823	[49]	[191]	3	hSpCas9	negative selection	12309476
96115533	96115556	2	-	28162770	OCIAML3	viability	GCCAAACGCAGCAACCGCAGAGG	ADRA2B	ENSG00000274286	0.6968935589425747	[46]	[229]	6	hSpCas9	negative selection	12309477
96115246	96115269	2	-	28162770	OCIAML3	viability	GGATGAAGCTGAAGAGGAGGAAG	ADRA2B	ENSG00000274286	-1.1300605405643729	[28]	[39]	-7	hSpCas9	negative selection	12309478
96115030	96115053	2	-	28162770	OCIAML3	viability	GAAGCGCTTCACCTTCGTGCTGG	ADRA2B	ENSG00000274286	1.1649842601720422	[25]	[175]	8	hSpCas9	negative selection	12309479
96114917	96114940	2	+	28162770	OCIAML3	viability	GAAGAACTGGAAGAGGCCATGGG	ADRA2B	ENSG00000274286	0.2776682627002973	[46]	[171]	2	hSpCas9	negative selection	12309480
96116122	96116145	2	+	28162770	OCIAML3	viability	GCACGGAGTAGGGGTCCTGGTGG	ADRA2B	ENSG00000274286	0.7698274062971225	[94]	[488]	7	hSpCas9	negative selection	12309481