Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:153
• Symbol:ADRB1
• Description:adrenoceptor beta 1

DataSource: http://genomecrispr.dkfz.de/#!/results/ADRB1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
114044244	114044267	10	-	26472758	Jiyoye	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-0.998081096980385	[97]	[36]	-6	hSpCas9	negative selection	3479
114045235	114045258	10	-	26472758	Jiyoye	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	3.86660700014317	[0]	[10]	9	hSpCas9	negative selection	3480
114044377	114044400	10	-	26472758	Jiyoye	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	-0.4082393103456823	[358]	[203]	-3	hSpCas9	negative selection	3481
114044482	114044505	10	-	26472758	Jiyoye	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	-0.49399459183470196	[408]	[218]	-4	hSpCas9	negative selection	3482
114044608	114044631	10	-	26472758	Jiyoye	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	-0.02140864961091815	[213]	[158]	0	hSpCas9	negative selection	3483
114044692	114044715	10	-	26472758	Jiyoye	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-0.17778711921528284	[95]	[63]	-1	hSpCas9	negative selection	3484
114044806	114044829	10	-	26472758	Jiyoye	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.23725038006356108	[125]	[111]	1	hSpCas9	negative selection	3485
114044854	114044877	10	-	26472758	Jiyoye	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	1.7791441588928316	[16]	[43]	8	hSpCas9	negative selection	3486
114045040	114045063	10	+	26472758	Jiyoye	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	3487
114045200	114045223	10	-	26472758	Jiyoye	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.34208035328398867	[67]	[64]	2	hSpCas9	negative selection	3488
114044244	114044267	10	-	26472758	KBM7	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	0.78262640320452	[427,282]	[519,70]	8	hSpCas9	negative selection	194597
114045235	114045258	10	-	26472758	KBM7	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-3.2620473271472985	[72,48]	[3,1]	-9	hSpCas9	negative selection	194598
114044377	114044400	10	-	26472758	KBM7	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.11322796058170548	[1203,790]	[573,431]	1	hSpCas9	negative selection	194599
114044482	114044505	10	-	26472758	KBM7	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.5255451989168057	[1114,705]	[593,614]	6	hSpCas9	negative selection	194600
114044608	114044631	10	-	26472758	KBM7	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.7201846617236847	[987,1097]	[1029,624]	7	hSpCas9	negative selection	194601
114044692	114044715	10	-	26472758	KBM7	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-0.4902340773502135	[518,342]	[104,174]	-4	hSpCas9	negative selection	194602
114044806	114044829	10	-	26472758	KBM7	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	1.0007900115953727	[683,481]	[739,363]	9	hSpCas9	negative selection	194603
114044854	114044877	10	-	26472758	KBM7	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	0.4689851256055759	[184,269]	[243,68]	5	hSpCas9	negative selection	194604
114045040	114045063	10	+	26472758	KBM7	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	0.7953867376318757	[11,30]	[0,33]	8	hSpCas9	negative selection	194605
114045200	114045223	10	-	26472758	KBM7	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.31074842389446655	[229,213]	[98,156]	3	hSpCas9	negative selection	194606
114044244	114044267	10	-	26472758	Raji	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-0.1150088859628483	[125]	[26]	-1	hSpCas9	negative selection	385715
114045235	114045258	10	-	26472758	Raji	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-0.5115262972708945	[42]	[6]	-4	hSpCas9	negative selection	385716
114044377	114044400	10	-	26472758	Raji	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.10738353537359946	[507]	[126]	1	hSpCas9	negative selection	385717
114044482	114044505	10	-	26472758	Raji	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.7552232390668218	[433]	[169]	7	hSpCas9	negative selection	385718
114044608	114044631	10	-	26472758	Raji	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.19363926872401838	[421]	[111]	1	hSpCas9	negative selection	385719
114044692	114044715	10	-	26472758	Raji	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-1.9630057925177984	[167]	[9]	-8	hSpCas9	negative selection	385720
114044806	114044829	10	-	26472758	Raji	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.8432259725808684	[256]	[106]	7	hSpCas9	negative selection	385721
114044854	114044877	10	-	26472758	Raji	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	0.21208091404029283	[92]	[24]	2	hSpCas9	negative selection	385722
114045040	114045063	10	+	26472758	Raji	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-1.699971386684005	[27]	[1]	-8	hSpCas9	negative selection	385723
114045200	114045223	10	-	26472758	Raji	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	-0.2582659369430807	[200]	[38]	-2	hSpCas9	negative selection	385724
114044244	114044267	10	-	26472758	K562	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-1.3354187408768419	[280]	[93]	-6	hSpCas9	negative selection	576833
114045235	114045258	10	-	26472758	K562	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-2.7555812723335524	[7]	[0]	-8	hSpCas9	negative selection	576834
114044377	114044400	10	-	26472758	K562	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	-0.19698347561179697	[993]	[731]	-1	hSpCas9	negative selection	576835
114044482	114044505	10	-	26472758	K562	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.7179236506564497	[676]	[939]	6	hSpCas9	negative selection	576836
114044608	114044631	10	-	26472758	K562	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	-0.03492444460093935	[942]	[776]	0	hSpCas9	negative selection	576837
114044692	114044715	10	-	26472758	K562	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-1.0514358556110222	[328]	[133]	-5	hSpCas9	negative selection	576838
114044806	114044829	10	-	26472758	K562	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.6218238482140972	[601]	[781]	5	hSpCas9	negative selection	576839
114044854	114044877	10	-	26472758	K562	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-1.1223636030051756	[195]	[75]	-6	hSpCas9	negative selection	576840
114045040	114045063	10	+	26472758	K562	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-0.943208275509325	[40]	[17]	-5	hSpCas9	negative selection	576841
114045200	114045223	10	-	26472758	K562	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.3288932958299834	[198]	[210]	2	hSpCas9	negative selection	576842
114044498	114044521	10	-	26627737	DLD1	viability	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	0.9336657905811494	[262]	[187,114,164]	8	hSpCas9	negative selection	773768
114044515	114044538	10	-	26627737	DLD1	viability	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.8858018823596835	[287]	[234,170,102]	8	hSpCas9	negative selection	773769
114044620	114044643	10	-	26627737	DLD1	viability	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.21167107435115626	[581]	[135,287,66]	-2	hSpCas9	negative selection	773770
114044838	114044861	10	-	26627737	DLD1	viability	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.3896216703009585	[1562]	[650,583,676]	4	hSpCas9	negative selection	773771
114044840	114044863	10	-	26627737	DLD1	viability	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.43796489525238436	[989]	[219,174,279]	-4	hSpCas9	negative selection	773772
114045299	114045322	10	+	26627737	DLD1	viability	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	0.00805243916384546	[161]	[71,64,20]	0	hSpCas9	negative selection	773773
114044498	114044521	10	-	26627737	GBM cells	viability after 5 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.29256726992307447	[176]	[77,76]	-4	hSpCas9	negative selection	856083
114044515	114044538	10	-	26627737	GBM cells	viability after 5 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.1020558173225366	[290]	[154,179]	1	hSpCas9	negative selection	856084
114044620	114044643	10	-	26627737	GBM cells	viability after 5 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.6936618099453458	[284]	[80,107]	-8	hSpCas9	negative selection	856085
114044838	114044861	10	-	26627737	GBM cells	viability after 5 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.29792440974448553	[885]	[391,380]	-5	hSpCas9	negative selection	856086
114044840	114044863	10	-	26627737	GBM cells	viability after 5 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.0746139137531232	[377]	[253,130]	-1	hSpCas9	negative selection	856087
114045299	114045322	10	+	26627737	GBM cells	viability after 5 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	0.8423303465193182	[51]	[59,39]	9	hSpCas9	negative selection	856088
114044498	114044521	10	-	26627737	GBM cells	viability after 13 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.08237821783985522	[176]	[125,61]	-1	hSpCas9	negative selection	938398
114044515	114044538	10	-	26627737	GBM cells	viability after 13 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.3883041338821051	[290]	[204,207]	5	hSpCas9	negative selection	938399
114044620	114044643	10	-	26627737	GBM cells	viability after 13 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	0.28699949865626917	[284]	[218,163]	3	hSpCas9	negative selection	938400
114044838	114044861	10	-	26627737	GBM cells	viability after 13 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.1200776043600591	[885]	[561,344]	-1	hSpCas9	negative selection	938401
114044840	114044863	10	-	26627737	GBM cells	viability after 13 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	0.05506826424038058	[377]	[222,204]	0	hSpCas9	negative selection	938402
114045299	114045322	10	+	26627737	GBM cells	viability after 13 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	0.6737522169935801	[51]	[60,31]	7	hSpCas9	negative selection	938403
114044498	114044521	10	-	26627737	GBM cells	viability after 21 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	0.13098937567101554	[176]	[109,100]	1	hSpCas9	negative selection	1020713
114044515	114044538	10	-	26627737	GBM cells	viability after 21 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.31789791524500705	[290]	[218,176]	3	hSpCas9	negative selection	1020714
114044620	114044643	10	-	26627737	GBM cells	viability after 21 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-1.0979960777131226	[284]	[87,57]	-7	hSpCas9	negative selection	1020715
114044838	114044861	10	-	26627737	GBM cells	viability after 21 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.15030203604553738	[885]	[451,416]	-1	hSpCas9	negative selection	1020716
114044840	114044863	10	-	26627737	GBM cells	viability after 21 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.744193955801995	[377]	[131,113]	-6	hSpCas9	negative selection	1020717
114045299	114045322	10	+	26627737	GBM cells	viability after 21 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	1.0504322911909547	[51]	[69,47]	9	hSpCas9	negative selection	1020718
114044498	114044521	10	-	26627737	RPE1	viability after 9 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	1.8763764441791182	[294]	[349,324]	8	hSpCas9	negative selection	1103028
114044515	114044538	10	-	26627737	RPE1	viability after 9 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.3325440958895182	[1009]	[326,489]	2	hSpCas9	negative selection	1103029
114044620	114044643	10	-	26627737	RPE1	viability after 9 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	4.341756745082886	[37]	[197,296]	9	hSpCas9	negative selection	1103030
114044838	114044861	10	-	26627737	RPE1	viability after 9 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.06726195440872784	[3178]	[1071,1004]	0	hSpCas9	negative selection	1103031
114044840	114044863	10	-	26627737	RPE1	viability after 9 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.7342268222596875	[822]	[191,106]	-5	hSpCas9	negative selection	1103032
114045299	114045322	10	+	26627737	RPE1	viability after 9 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	2.917385263714569	[67]	[107,228]	9	hSpCas9	negative selection	1103033
114044498	114044521	10	-	26627737	RPE1	viability after 12 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	1.4544205603409337	[294]	[223,209]	7	hSpCas9	negative selection	1185343
114044515	114044538	10	-	26627737	RPE1	viability after 12 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.4871285352301064	[1009]	[391,367]	3	hSpCas9	negative selection	1185344
114044620	114044643	10	-	26627737	RPE1	viability after 12 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	4.369869032267024	[37]	[230,189]	9	hSpCas9	negative selection	1185345
114044838	114044861	10	-	26627737	RPE1	viability after 12 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.04083147013406618	[3178]	[1008,640]	0	hSpCas9	negative selection	1185346
114044840	114044863	10	-	26627737	RPE1	viability after 12 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	0.13939465208924903	[822]	[244,241]	1	hSpCas9	negative selection	1185347
114045299	114045322	10	+	26627737	RPE1	viability after 12 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	2.7086527804460774	[67]	[48,193]	9	hSpCas9	negative selection	1185348
114044498	114044521	10	-	26627737	RPE1	viability after 15 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	1.387561342087314	[294]	[283,154]	7	hSpCas9	negative selection	1267658
114044515	114044538	10	-	26627737	RPE1	viability after 15 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.34690893290837405	[1009]	[454,274]	2	hSpCas9	negative selection	1267659
114044620	114044643	10	-	26627737	RPE1	viability after 15 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	5.2173347878160845	[37]	[348,448]	9	hSpCas9	negative selection	1267660
114044838	114044861	10	-	26627737	RPE1	viability after 15 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.08206528862966578	[3178]	[1043,661]	0	hSpCas9	negative selection	1267661
114044840	114044863	10	-	26627737	RPE1	viability after 15 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.35081791617394187	[822]	[291,76]	-2	hSpCas9	negative selection	1267662
114045299	114045322	10	+	26627737	RPE1	viability after 15 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	2.784774926086575	[67]	[72,189]	9	hSpCas9	negative selection	1267663
114044498	114044521	10	-	26627737	RPE1	viability after 18 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	1.8823720481374753	[294]	[322,261]	8	hSpCas9	negative selection	1349973
114044515	114044538	10	-	26627737	RPE1	viability after 18 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.3925803001481947	[1009]	[395,316]	2	hSpCas9	negative selection	1349974
114044620	114044643	10	-	26627737	RPE1	viability after 18 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	5.104063713683988	[37]	[314,392]	9	hSpCas9	negative selection	1349975
114044838	114044861	10	-	26627737	RPE1	viability after 18 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.40417444235353606	[3178]	[758,529]	-3	hSpCas9	negative selection	1349976
114044840	114044863	10	-	26627737	RPE1	viability after 18 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	0.539568907457389	[822]	[521,109]	3	hSpCas9	negative selection	1349977
114045299	114045322	10	+	26627737	RPE1	viability after 18 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	3.055341547498575	[67]	[51,259]	9	hSpCas9	negative selection	1349978
114044498	114044521	10	-	26627737	HeLa	viability after 8 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-1.2067730635126228	[471]	[176,74,37]	-8	hSpCas9	negative selection	1432288
114044515	114044538	10	-	26627737	HeLa	viability after 8 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.5305693592189671	[309]	[271,111,215]	5	hSpCas9	negative selection	1432289
114044620	114044643	10	-	26627737	HeLa	viability after 8 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	0.013626516840070282	[387]	[356,63,133]	0	hSpCas9	negative selection	1432290
114044838	114044861	10	-	26627737	HeLa	viability after 8 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.2465648511363252	[1121]	[877,443,487]	2	hSpCas9	negative selection	1432291
114044840	114044863	10	-	26627737	HeLa	viability after 8 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-1.1800754559309201	[867]	[156,115,220]	-8	hSpCas9	negative selection	1432292
114045299	114045322	10	+	26627737	HeLa	viability after 8 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	2.1634739813658412	[17]	[75,13,24]	9	hSpCas9	negative selection	1432293
114044498	114044521	10	-	26627737	HeLa	viability after 12 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.32352433306954653	[471]	[238,127,105]	-3	hSpCas9	negative selection	1514603
114044515	114044538	10	-	26627737	HeLa	viability after 12 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.7430517482328944	[309]	[106,111,431]	6	hSpCas9	negative selection	1514604
114044620	114044643	10	-	26627737	HeLa	viability after 12 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	0.4060748924082115	[387]	[282,197,159]	3	hSpCas9	negative selection	1514605
114044838	114044861	10	-	26627737	HeLa	viability after 12 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.0969235937516233	[1121]	[443,478,564]	0	hSpCas9	negative selection	1514606
114044840	114044863	10	-	26627737	HeLa	viability after 12 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-1.3290834879392872	[867]	[1,144,276]	-8	hSpCas9	negative selection	1514607
114045299	114045322	10	+	26627737	HeLa	viability after 12 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	3.226634493566767	[17]	[101,86,18]	9	hSpCas9	negative selection	1514608
114044498	114044521	10	-	26627737	HeLa	viability after 15 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.5168898944920111	[471]	[176,106,116]	-4	hSpCas9	negative selection	1596918
114044515	114044538	10	-	26627737	HeLa	viability after 15 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.6746303574666599	[309]	[214,104,290]	5	hSpCas9	negative selection	1596919
114044620	114044643	10	-	26627737	HeLa	viability after 15 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	0.6273702162614035	[387]	[326,134,270]	5	hSpCas9	negative selection	1596920
114044838	114044861	10	-	26627737	HeLa	viability after 15 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.02157518205082587	[1121]	[501,369,522]	0	hSpCas9	negative selection	1596921
114044840	114044863	10	-	26627737	HeLa	viability after 15 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.5997348693905851	[867]	[405,97,189]	-5	hSpCas9	negative selection	1596922
114045299	114045322	10	+	26627737	HeLa	viability after 15 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	2.6183410423456817	[17]	[55,31,46]	9	hSpCas9	negative selection	1596923
114044498	114044521	10	-	26627737	HeLa	viability after 18 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.5540381757095325	[471]	[110,89,116]	-5	hSpCas9	negative selection	1679233
114044515	114044538	10	-	26627737	HeLa	viability after 18 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.6943324680824141	[309]	[151,83,290]	5	hSpCas9	negative selection	1679234
114044620	114044643	10	-	26627737	HeLa	viability after 18 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	0.6278771352821924	[387]	[216,114,270]	5	hSpCas9	negative selection	1679235
114044838	114044861	10	-	26627737	HeLa	viability after 18 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.0031443849228309784	[1121]	[324,301,522]	0	hSpCas9	negative selection	1679236
114044840	114044863	10	-	26627737	HeLa	viability after 18 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.6058872087130068	[867]	[272,77,189]	-5	hSpCas9	negative selection	1679237
114045299	114045322	10	+	26627737	HeLa	viability after 18 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	2.6122020462743505	[17]	[39,22,46]	9	hSpCas9	negative selection	1679238
114044498	114044521	10	-	26627737	HCT116	viability after 6 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.09392276864959159	[1186]	[43,246]	0	hSpCas9	negative selection	1761548
114044515	114044538	10	-	26627737	HCT116	viability after 6 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	-0.39610789537671964	[633]	[174,20]	-2	hSpCas9	negative selection	1761549
114044620	114044643	10	-	26627737	HCT116	viability after 6 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.569289290080035	[241]	[53,9]	-3	hSpCas9	negative selection	1761550
114044838	114044861	10	-	26627737	HCT116	viability after 6 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	1.748805829668595	[988]	[401,588]	8	hSpCas9	negative selection	1761551
114044840	114044863	10	-	26627737	HCT116	viability after 6 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-1.8461135225854153	[2502]	[238,37]	-8	hSpCas9	negative selection	1761552
114045299	114045322	10	+	26627737	HCT116	viability after 6 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	0.5766146737957467	[112]	[1,39]	3	hSpCas9	negative selection	1761553
114044498	114044521	10	-	26627737	HCT116	viability after 8 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.5732398856477827	[280]	[59,112,137]	-6	hSpCas9	negative selection	1843863
114044515	114044538	10	-	26627737	HCT116	viability after 8 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.5953423533905462	[266]	[237,196,231]	6	hSpCas9	negative selection	1843864
114044620	114044643	10	-	26627737	HCT116	viability after 8 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.20604690895631614	[265]	[36,166,174]	-2	hSpCas9	negative selection	1843865
114044838	114044861	10	-	26627737	HCT116	viability after 8 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.4582963281001863	[570]	[506,425,365]	5	hSpCas9	negative selection	1843866
114044840	114044863	10	-	26627737	HCT116	viability after 8 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.7110313386217358	[498]	[136,168,196]	-7	hSpCas9	negative selection	1843867
114045299	114045322	10	+	26627737	HCT116	viability after 8 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	1.1253484597393681	[30]	[83,21,6]	8	hSpCas9	negative selection	1843868
114044498	114044521	10	-	26627737	HCT116	viability after 9 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-3.4823104491310577	[1186]	[43,15]	-9	hSpCas9	negative selection	1926178
114044515	114044538	10	-	26627737	HCT116	viability after 9 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.8118448725003837	[633]	[242,339]	6	hSpCas9	negative selection	1926179
114044620	114044643	10	-	26627737	HCT116	viability after 9 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	1.4318312096046593	[241]	[256,108]	8	hSpCas9	negative selection	1926180
114044838	114044861	10	-	26627737	HCT116	viability after 9 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	1.2300711212059432	[988]	[819,460]	7	hSpCas9	negative selection	1926181
114044840	114044863	10	-	26627737	HCT116	viability after 9 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-2.3128454582867937	[2502]	[162,111]	-9	hSpCas9	negative selection	1926182
114045299	114045322	10	+	26627737	HCT116	viability after 9 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	0.7909879284820092	[112]	[116,0]	5	hSpCas9	negative selection	1926183
114044498	114044521	10	-	26627737	HCT116	viability after 12 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.15893030687915147	[280]	[62,177,162]	-2	hSpCas9	negative selection	2008493
114044515	114044538	10	-	26627737	HCT116	viability after 12 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.042987724558916834	[266]	[177,113,137]	0	hSpCas9	negative selection	2008494
114044620	114044643	10	-	26627737	HCT116	viability after 12 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.718036115773665	[265]	[43,144,70]	-7	hSpCas9	negative selection	2008495
114044838	114044861	10	-	26627737	HCT116	viability after 12 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.33819969118230475	[570]	[472,427,229]	3	hSpCas9	negative selection	2008496
114044840	114044863	10	-	26627737	HCT116	viability after 12 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.4357968149170546	[498]	[194,172,212]	-5	hSpCas9	negative selection	2008497
114045299	114045322	10	+	26627737	HCT116	viability after 12 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	1.308633030285168	[30]	[70,24,21]	8	hSpCas9	negative selection	2008498
114044498	114044521	10	-	26627737	HCT116	viability after 15 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.3322913871559945	[280]	[82,164,130]	-3	hSpCas9	negative selection	2090808
114044515	114044538	10	-	26627737	HCT116	viability after 15 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.8326208904582202	[266]	[365,145,317]	7	hSpCas9	negative selection	2090809
114044620	114044643	10	-	26627737	HCT116	viability after 15 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-1.1505620925598552	[265]	[39,99,62]	-8	hSpCas9	negative selection	2090810
114044838	114044861	10	-	26627737	HCT116	viability after 15 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.7071188634828319	[570]	[681,581,361]	6	hSpCas9	negative selection	2090811
114044840	114044863	10	-	26627737	HCT116	viability after 15 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.7524177429248751	[498]	[148,207,150]	-6	hSpCas9	negative selection	2090812
114045299	114045322	10	+	26627737	HCT116	viability after 15 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	1.4056668725245525	[30]	[81,37,25]	9	hSpCas9	negative selection	2090813
114044498	114044521	10	-	26627737	HCT116	viability after 18 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.1946633936688605	[280]	[113,112,129]	-2	hSpCas9	negative selection	2173123
114044515	114044538	10	-	26627737	HCT116	viability after 18 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	1.1133759082342773	[266]	[180,317,338]	8	hSpCas9	negative selection	2173124
114044620	114044643	10	-	26627737	HCT116	viability after 18 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-1.1925948913794366	[265]	[24,92,47]	-8	hSpCas9	negative selection	2173125
114044838	114044861	10	-	26627737	HCT116	viability after 18 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.2924590594687714	[570]	[381,347,280]	2	hSpCas9	negative selection	2173126
114044840	114044863	10	-	26627737	HCT116	viability after 18 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-1.2613609827735364	[498]	[196,25,82]	-8	hSpCas9	negative selection	2173127
114045299	114045322	10	+	26627737	HCT116	viability after 18 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	1.866684699454581	[30]	[86,23,54]	9	hSpCas9	negative selection	2173128
114044120	114044143	10	+	24336569	HL60	viability	TCCGCAGCTCGGCATGGGCGCGG	ADRB1	ENSG00000043591	1.6803761621763393	[298]	[2027]	9	hSpCas9	negative selection	2246822
114044151	114044174	10	+	24336569	HL60	viability	GTCCTGGGCGCCTCCGAGCCCGG	ADRB1	ENSG00000043591	0.4270546427201543	[393]	[1120]	4	hSpCas9	negative selection	2246823
114044161	114044184	10	-	24336569	HL60	viability	CGACAGGTTACCGGGCTCGGAGG	ADRB1	ENSG00000043591	0.8838818303434185	[157]	[616]	7	hSpCas9	negative selection	2246824
114044169	114044192	10	-	24336569	HL60	viability	GCGGCCGACGACAGGTTACCGGG	ADRB1	ENSG00000043591	0.17074553131330616	[300]	[716]	1	hSpCas9	negative selection	2246825
114044177	114044200	10	-	24336569	HL60	viability	GGAGCGGTGCGGCCGACGACAGG	ADRB1	ENSG00000043591	0.29667064304043067	[588]	[1530]	3	hSpCas9	negative selection	2246826
114044235	114044258	10	-	24336569	HL60	viability	AACGAGGCGGGCGGCGACGCGGG	ADRB1	ENSG00000043591	0.26645920279141067	[439]	[1119]	2	hSpCas9	negative selection	2246827
114044244	114044267	10	-	24336569	HL60	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-0.6276212753323236	[916]	[1255]	-5	hSpCas9	negative selection	2246828
114044251	114044274	10	-	24336569	HL60	viability	GCTGGCGGGAGGCAGCAACGAGG	ADRB1	ENSG00000043591	-0.8480751565436272	[1474]	[1733]	-6	hSpCas9	negative selection	2246829
114044280	114044303	10	-	24336569	HL60	viability	CACTGCTGAGACAGCGGCTCGGG	ADRB1	ENSG00000043591	0.6792646615573521	[282]	[958]	6	hSpCas9	negative selection	2246830
114044286	114044309	10	-	24336569	HL60	viability	GCTGTCCACTGCTGAGACAGCGG	ADRB1	ENSG00000043591	-0.5889478486723353	[434]	[611]	-5	hSpCas9	negative selection	2246831
114044120	114044143	10	+	24336569	KBM7	viability	TCCGCAGCTCGGCATGGGCGCGG	ADRB1	ENSG00000043591	-0.2043464319305739	[647]	[1533]	-2	hSpCas9	negative selection	2313999
114044151	114044174	10	+	24336569	KBM7	viability	GTCCTGGGCGCCTCCGAGCCCGG	ADRB1	ENSG00000043591	0.7956745842105672	[357]	[1694]	7	hSpCas9	negative selection	2314000
114044161	114044184	10	-	24336569	KBM7	viability	CGACAGGTTACCGGGCTCGGAGG	ADRB1	ENSG00000043591	0.8421855748994332	[126]	[620]	7	hSpCas9	negative selection	2314001
114044169	114044192	10	-	24336569	KBM7	viability	GCGGCCGACGACAGGTTACCGGG	ADRB1	ENSG00000043591	0.8926982082173717	[124]	[632]	7	hSpCas9	negative selection	2314002
114044177	114044200	10	-	24336569	KBM7	viability	GGAGCGGTGCGGCCGACGACAGG	ADRB1	ENSG00000043591	0.3932675414442024	[662]	[2374]	3	hSpCas9	negative selection	2314003
114044235	114044258	10	-	24336569	KBM7	viability	AACGAGGCGGGCGGCGACGCGGG	ADRB1	ENSG00000043591	-0.17918390544654333	[290]	[700]	-1	hSpCas9	negative selection	2314004
114044244	114044267	10	-	24336569	KBM7	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-1.1350519115083955	[892]	[1108]	-7	hSpCas9	negative selection	2314005
114044251	114044274	10	-	24336569	KBM7	viability	GCTGGCGGGAGGCAGCAACGAGG	ADRB1	ENSG00000043591	-1.2751676718880005	[1094]	[1233]	-7	hSpCas9	negative selection	2314006
114044280	114044303	10	-	24336569	KBM7	viability	CACTGCTGAGACAGCGGCTCGGG	ADRB1	ENSG00000043591	-0.009590817781852001	[646]	[1752]	0	hSpCas9	negative selection	2314007
114044286	114044309	10	-	24336569	KBM7	viability	GCTGTCCACTGCTGAGACAGCGG	ADRB1	ENSG00000043591	-0.5748143848449903	[307]	[563]	-4	hSpCas9	negative selection	2314008
114044498	114044521	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.23748072339210255	[3,3]	[1,2]	-3	hSpCas9	positive selection	2969215
114044818	114044841	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGCACGTAGAAGGAGACTACGG	ADRB1	ENSG00000043591	-0.6784981780226624	[4,4]	[3,0]	-8	hSpCas9	positive selection	2969216
114044812	114044835	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGAAGGAGACTACGGACGAGG	ADRB1	ENSG00000043591	-0.7754894273026465	[3,3]	[2,0]	-8	hSpCas9	positive selection	2969217
114044375	114044398	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGGCCATCGCCAAGACGCCGCGG	ADRB1	ENSG00000043591	0.048814523439377734	[3,3]	[1,3]	1	hSpCas9	positive selection	2969218
114044498	114044521	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	0.09740655296672546	[3,3]	[2,2]	1	hSpCas9	positive selection	3037073
114044818	114044841	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGCACGTAGAAGGAGACTACGG	ADRB1	ENSG00000043591	-0.06862087840793946	[4,4]	[3,1]	-1	hSpCas9	positive selection	3037074
114044812	114044835	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGAAGGAGACTACGGACGAGG	ADRB1	ENSG00000043591	0.5388090064177192	[3,3]	[2,3]	8	hSpCas9	positive selection	3037075
114044375	114044398	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGGCCATCGCCAAGACGCCGCGG	ADRB1	ENSG00000043591	0.18975615453770134	[3,3]	[2,2]	3	hSpCas9	positive selection	3037076
114045037	114045060		-	24336571	A375	resistance to PLX after 7 days	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	-0.368668421351319	[18,14]	[11,13]	-9	hSpCas9	positive selection	3107333
114044800	114044823		-	24336571	A375	resistance to PLX after 7 days	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.24020042859451785	[8,5]	[6,5]	-7	hSpCas9	positive selection	3107344
114045037	114045060		-	24336571	A375	resistance to PLX after 14 days	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	-0.5579088886665188	[17,17]	[3,5]	-6	hSpCas9	positive selection	3165126
114044800	114044823		-	24336571	A375	resistance to PLX after 14 days	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.7047657940332969	[10,11]	[2,2]	-7	hSpCas9	positive selection	3165137
114045037	114045060		-	24336571	A375	viability after 7 days	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.18336874620894858	[15]	[18,14]	2	hSpCas9	negative selection	3222919
114044800	114044823		-	24336571	A375	viability after 7 days	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	0.2784615133530458	[6]	[8,5]	4	hSpCas9	negative selection	3222930
114045037	114045060		-	24336571	A375	viability after 14 days	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.24111622377773026	[15]	[17,17]	3	hSpCas9	negative selection	3280712
114044800	114044823		-	24336571	A375	viability after 14 days	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	0.8443462193298525	[6]	[10,11]	9	hSpCas9	negative selection	3280723
114045037	114045060	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	2.302906857714481	[237,226]	[1,12]	8	hSpCas9	positive selection	3335794
114044800	114044823	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	2.234233243820113	[34,29]	[0,0]	7	hSpCas9	positive selection	3335795
114045037	114045060	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	1.988214815001921	[47,28]	[0,0]	7	hSpCas9	positive selection	3335796
114044164	114044187	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.9275491314624489	[290,290]	[0,0]	-6	hSpCas9	positive selection	3355043
114044468	114044491	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.10022579317224871	[163,163]	[0,0]	0	hSpCas9	positive selection	3355044
114044632	114044655	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	1.5024387092823666	[53,53]	[0,0]	6	hSpCas9	positive selection	3355045
114044498	114044521	10	-	26780180	HT29	viability (Avana library 4 designs)	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.537783993670902	[]	[]	-7	hSpCas9	negative selection	3405281
114044818	114044841	10	-	26780180	HT29	viability (Avana library 4 designs)	GGGCACGTAGAAGGAGACTACGG	ADRB1	ENSG00000043591	1.1977943830882	[]	[]	5	hSpCas9	negative selection	3405282
114044812	114044835	10	-	26780180	HT29	viability (Avana library 4 designs)	GTAGAAGGAGACTACGGACGAGG	ADRB1	ENSG00000043591	1.22149255039635	[]	[]	5	hSpCas9	negative selection	3405283
114044374	114044397	10	+	26780180	HT29	viability (Avana library 4 designs)	TGGCCATCGCCAAGACGCCGCGG	ADRB1	ENSG00000043591	0.130062715549353	[]	[]	0	hSpCas9	negative selection	3405284
114044374	114044397	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGGCCATCGCCAAGACGCCGCGG	ADRB1	ENSG00000043591	4.67321742449974	[]	[]	7	hSpCas9	negative selection	3477214
114044498	114044521	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	3.03618783076461	[]	[]	4	hSpCas9	negative selection	3477215
114044812	114044835	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGAAGGAGACTACGGACGAGG	ADRB1	ENSG00000043591	2.99305099562144	[]	[]	4	hSpCas9	negative selection	3477216
114044818	114044841	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGCACGTAGAAGGAGACTACGG	ADRB1	ENSG00000043591	0.100940766784108	[]	[]	0	hSpCas9	negative selection	3477217
114044614	114044637	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCTGGTAGCGGAAGGGCGAGG	ADRB1	ENSG00000043591	6.89085427033867	[]	[]	9	hSpCas9	negative selection	3477218
114044692	114044715	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-1.64819791025956	[]	[]	-2	hSpCas9	negative selection	3477219
114044374	114044397	10	+	26780180	A375	viability (Avana lentiGuide)	TGGCCATCGCCAAGACGCCGCGG	ADRB1	ENSG00000043591	1.78244774185017	[]	[]	2	hSpCas9	negative selection	3585873
114044498	114044521	10	-	26780180	A375	viability (Avana lentiGuide)	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-1.8731904464177	[]	[]	-3	hSpCas9	negative selection	3585874
114044812	114044835	10	-	26780180	A375	viability (Avana lentiGuide)	GTAGAAGGAGACTACGGACGAGG	ADRB1	ENSG00000043591	-3.02303017173069	[]	[]	-5	hSpCas9	negative selection	3585875
114044818	114044841	10	-	26780180	A375	viability (Avana lentiGuide)	GGGCACGTAGAAGGAGACTACGG	ADRB1	ENSG00000043591	5.59404571437734	[]	[]	5	hSpCas9	negative selection	3585876
114044614	114044637	10	-	26780180	A375	viability (Avana lentiGuide)	GCTCTGGTAGCGGAAGGGCGAGG	ADRB1	ENSG00000043591	-0.843031258202394	[]	[]	-1	hSpCas9	negative selection	3585877
114044692	114044715	10	-	26780180	A375	viability (Avana lentiGuide)	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	17.8172967343396	[]	[]	8	hSpCas9	negative selection	3585878
114044374	114044397	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGCCATCGCCAAGACGCCGCGG	ADRB1	ENSG00000043591	-0.21237373161844203	[3]	[2,3]	-3	hSpCas9	positive selection	3694532
114044498	114044521	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	0.12474081219324354	[4]	[5,4]	3	hSpCas9	positive selection	3694533
114044812	114044835	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGAAGGAGACTACGGACGAGG	ADRB1	ENSG00000043591	0.17545866142949118	[4]	[4,4]	5	hSpCas9	positive selection	3694534
114044818	114044841	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGCACGTAGAAGGAGACTACGG	ADRB1	ENSG00000043591	0.2544763267591834	[5]	[6,5]	7	hSpCas9	positive selection	3694535
114044614	114044637	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCTGGTAGCGGAAGGGCGAGG	ADRB1	ENSG00000043591	0.45726528620971896	[3]	[5,5]	9	hSpCas9	positive selection	3694536
114044692	114044715	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-0.01601648532365614	[5]	[5,4]	0	hSpCas9	positive selection	3694537
114044374	114044397	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGCCATCGCCAAGACGCCGCGG	ADRB1	ENSG00000043591	-0.1940701014583433	[5]	[4,3]	-3	hSpCas9	positive selection	3803139
114044498	114044521	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-1.083029568072513	[4]	[1,0]	-8	hSpCas9	positive selection	3803140
114044812	114044835	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGAAGGAGACTACGGACGAGG	ADRB1	ENSG00000043591	-0.4733639105382672	[4]	[2,2]	-6	hSpCas9	positive selection	3803141
114044818	114044841	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGCACGTAGAAGGAGACTACGG	ADRB1	ENSG00000043591	0.1820156637656005	[5]	[5,5]	4	hSpCas9	positive selection	3803142
114044614	114044637	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCTGGTAGCGGAAGGGCGAGG	ADRB1	ENSG00000043591	0.3921218698418963	[4]	[4,5]	9	hSpCas9	positive selection	3803143
114044692	114044715	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-0.5513719587194211	[6]	[4,1]	-6	hSpCas9	positive selection	3803144
114044632	114044655	10	+	26780180	A375	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.621252861367493	[]	[]	2	hSpCas9	negative selection	3911604
114045037	114045060	10	+	26780180	A375	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.490098332379691	[]	[]	1	hSpCas9	negative selection	3911605
114045037	114045060	10	-	26780180	A375	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.62215067946346	[]	[]	2	hSpCas9	negative selection	3911606
114044164	114044187	10	-	26780180	A375	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.705829558764829	[]	[]	2	hSpCas9	negative selection	3911607
114044468	114044491	10	+	26780180	A375	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	1.06106636247557	[]	[]	5	hSpCas9	negative selection	3911608
114044800	114044823	10	-	26780180	A375	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	1.08479141018232	[]	[]	5	hSpCas9	negative selection	3911609
114044632	114044655	10	+	26780180	HT29	viability (GeCKOv2 library)	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.41691038535154	[]	[]	1	hSpCas9	negative selection	4019570
114045037	114045060	10	+	26780180	HT29	viability (GeCKOv2 library)	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	-0.525830060876797	[]	[]	-9	hSpCas9	negative selection	4019571
114045037	114045060	10	-	26780180	HT29	viability (GeCKOv2 library)	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.820524321907776	[]	[]	3	hSpCas9	negative selection	4019572
114044164	114044187	10	-	26780180	HT29	viability (GeCKOv2 library)	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	1.00673999669288	[]	[]	4	hSpCas9	negative selection	4019573
114044468	114044491	10	+	26780180	HT29	viability (GeCKOv2 library)	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	1.36871365233157	[]	[]	7	hSpCas9	negative selection	4019574
114044800	114044823	10	-	26780180	HT29	viability (GeCKOv2 library)	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	0.835585479544655	[]	[]	3	hSpCas9	negative selection	4019575
114045037	114045060	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.028753259448455006	[3]	[2,2]	0	hSpCas9	positive selection	4129589
114044800	114044823	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.41396479742963355	[3]	[1,1]	-8	hSpCas9	positive selection	4129600
114045037	114045060	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.6632894939987566	[4]	[3,0,1,3]	4	hSpCas9	positive selection	4193611
114044800	114044823	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	1.2295244739618494	[2]	[1,2,2,3]	8	hSpCas9	positive selection	4193622
114045037	114045060	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.38481353029640913	[3]	[4,3]	7	hSpCas9	positive selection	4254758
114044800	114044823	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.12643941785168145	[2]	[1,0]	-2	hSpCas9	positive selection	4254759
114045037	114045060	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.3237902134396084	[1]	[2,0]	6	hSpCas9	positive selection	4254760
114044164	114044187	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.22456528022470923	[3]	[3,2]	4	hSpCas9	positive selection	4319040
114044468	114044491	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.239597478031598	[3]	[1,1]	-5	hSpCas9	positive selection	4319041
114044632	114044655	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.20957783528721835	[1]	[1,0]	4	hSpCas9	positive selection	4319042
114044619	114044641	10	-	27760321	OCIAML3	viability	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	0.1606572958336634	[758,585]	[432,779]	1	hSpCas9	negative selection	4376536
114044709	114044731	10	-	27760321	OCIAML3	viability	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	0.4189092367345917	[565,412]	[433,601]	5	hSpCas9	negative selection	4376537
114044778	114044800	10	+	27760321	OCIAML3	viability	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	0.5266875294847282	[544,483]	[428,773]	6	hSpCas9	negative selection	4376538
114044806	114044828	10	-	27760321	OCIAML3	viability	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.44598059275579227	[401,398]	[318,569]	5	hSpCas9	negative selection	4376539
114044838	114044860	10	-	27760321	OCIAML3	viability	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.17087571745009555	[444,351]	[286,428]	2	hSpCas9	negative selection	4376540
114044619	114044641	10	-	27760321	OCIAML2	viability	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	-0.043888249756425024	[758,585]	[456,611]	0	hSpCas9	negative selection	4459999
114044709	114044731	10	-	27760321	OCIAML2	viability	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	0.5339988583181214	[565,412]	[437,738]	7	hSpCas9	negative selection	4460000
114044778	114044800	10	+	27760321	OCIAML2	viability	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	0.18365334229323454	[544,483]	[351,629]	2	hSpCas9	negative selection	4460001
114044806	114044828	10	-	27760321	OCIAML2	viability	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.35457694248737903	[401,398]	[364,481]	5	hSpCas9	negative selection	4460002
114044838	114044860	10	-	27760321	OCIAML2	viability	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.5464838152082525	[444,351]	[403,551]	7	hSpCas9	negative selection	4460003
114044619	114044641	10	-	27760321	MV411	viability	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	0.162163089331678	[758,585]	[450,555]	1	hSpCas9	negative selection	4543462
114044709	114044731	10	-	27760321	MV411	viability	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	0.8204906525981793	[565,412]	[580,540]	6	hSpCas9	negative selection	4543463
114044778	114044800	10	+	27760321	MV411	viability	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	-0.510890056194899	[544,483]	[109,429]	-4	hSpCas9	negative selection	4543464
114044806	114044828	10	-	27760321	MV411	viability	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	-0.21076103076341746	[401,398]	[45,503]	-1	hSpCas9	negative selection	4543465
114044838	114044860	10	-	27760321	MV411	viability	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	1.6976294433917123	[444,351]	[1114,445]	9	hSpCas9	negative selection	4543466
114044619	114044641	10	-	27760321	HL60	viability	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	1.2132187867417699	[758,585]	[1261,1266]	9	hSpCas9	negative selection	4626925
114044709	114044731	10	-	27760321	HL60	viability	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	0.6137133057639316	[565,412]	[523,692]	7	hSpCas9	negative selection	4626926
114044778	114044800	10	+	27760321	HL60	viability	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	0.4239708663910376	[544,483]	[594,528]	5	hSpCas9	negative selection	4626927
114044806	114044828	10	-	27760321	HL60	viability	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	-0.08808212642044855	[401,398]	[248,371]	-1	hSpCas9	negative selection	4626928
114044838	114044860	10	-	27760321	HL60	viability	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.13965622706834396	[444,351]	[334,378]	1	hSpCas9	negative selection	4626929
114044619	114044641	10	-	27760321	HT1080	viability	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	1.0576687045242918	[585,456]	[472,387]	6	hSpCas9	negative selection	4710388
114044709	114044731	10	-	27760321	HT1080	viability	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	1.7867765034922676	[412,321]	[359,663]	8	hSpCas9	negative selection	4710389
114044778	114044800	10	+	27760321	HT1080	viability	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	0.7678779818331035	[483,377]	[99,502]	4	hSpCas9	negative selection	4710390
114044806	114044828	10	-	27760321	HT1080	viability	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	2.1697215612289242	[398,311]	[874,376]	9	hSpCas9	negative selection	4710391
114044838	114044860	10	-	27760321	HT1080	viability	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	1.1667874603485116	[351,274]	[288,270]	6	hSpCas9	negative selection	4710392
114044619	114044641	10	-	27760321	HT29	viability after 7 days	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	0.5332691514254416	[585,456]	[1270,1016,673]	7	hSpCas9	negative selection	4793851
114044709	114044731	10	-	27760321	HT29	viability after 7 days	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	1.0479910877394867	[412,321]	[961,1014,950]	9	hSpCas9	negative selection	4793852
114044778	114044800	10	+	27760321	HT29	viability after 7 days	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	-0.31956884972746524	[483,377]	[595,306,449]	-4	hSpCas9	negative selection	4793853
114044806	114044828	10	-	27760321	HT29	viability after 7 days	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.5453011512866536	[398,311]	[650,1028,328]	8	hSpCas9	negative selection	4793854
114044838	114044860	10	-	27760321	HT29	viability after 7 days	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.42825373945463896	[351,274]	[620,580,438]	6	hSpCas9	negative selection	4793855
114044619	114044641	10	-	27760321	HT29	viability after 25 days	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	0.7786285858726459	[585,456]	[922,710,1485]	8	hSpCas9	negative selection	4877314
114044709	114044731	10	-	27760321	HT29	viability after 25 days	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	1.209023471859643	[412,321]	[883,1247,762]	9	hSpCas9	negative selection	4877315
114044778	114044800	10	+	27760321	HT29	viability after 25 days	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	-0.31020644247484264	[483,377]	[245,451,514]	-3	hSpCas9	negative selection	4877316
114044806	114044828	10	-	27760321	HT29	viability after 25 days	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.452429637812231	[398,311]	[765,442,431]	5	hSpCas9	negative selection	4877317
114044838	114044860	10	-	27760321	HT29	viability after 25 days	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	1.0988342551234318	[351,274]	[853,868,549]	9	hSpCas9	negative selection	4877318
114044619	114044641	10	-	27760321	HT29	viability after 22 days	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	0.7813684626756631	[585,456]	[773,940,1403]	8	hSpCas9	negative selection	4960777
114044709	114044731	10	-	27760321	HT29	viability after 22 days	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	1.020679561478343	[412,321]	[617,932,1042]	9	hSpCas9	negative selection	4960778
114044778	114044800	10	+	27760321	HT29	viability after 22 days	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	-0.3372319238462315	[483,377]	[340,519,322]	-3	hSpCas9	negative selection	4960779
114044806	114044828	10	-	27760321	HT29	viability after 22 days	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.5672002353144364	[398,311]	[703,446,673]	6	hSpCas9	negative selection	4960780
114044838	114044860	10	-	27760321	HT29	viability after 22 days	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.9959455291602359	[351,274]	[578,809,783]	9	hSpCas9	negative selection	4960781
114044619	114044641	10	-	27760321	HT29	viability after 19 days	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	0.3617358283002773	[585,456]	[888,752,672]	3	hSpCas9	negative selection	5044240
114044709	114044731	10	-	27760321	HT29	viability after 19 days	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	0.9353361476071252	[412,321]	[958,1043,437]	8	hSpCas9	negative selection	5044241
114044778	114044800	10	+	27760321	HT29	viability after 19 days	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	0.12550509545208482	[483,377]	[647,748,238]	1	hSpCas9	negative selection	5044242
114044806	114044828	10	-	27760321	HT29	viability after 19 days	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.3537100879484904	[398,311]	[531,487,538]	3	hSpCas9	negative selection	5044243
114044838	114044860	10	-	27760321	HT29	viability after 19 days	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.8554622969894774	[351,274]	[761,661,537]	8	hSpCas9	negative selection	5044244
114044619	114044641	10	-	27760321	HT29	viability after 16 days	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	1.0803817398029278	[585,456]	[1071,1067,1549]	9	hSpCas9	negative selection	5127703
114044709	114044731	10	-	27760321	HT29	viability after 16 days	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	1.2264608688786762	[412,321]	[1330,914,675]	9	hSpCas9	negative selection	5127704
114044778	114044800	10	+	27760321	HT29	viability after 16 days	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	-0.2634106548279822	[483,377]	[632,287,308]	-3	hSpCas9	negative selection	5127705
114044806	114044828	10	-	27760321	HT29	viability after 16 days	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.4651947990558186	[398,311]	[608,471,573]	5	hSpCas9	negative selection	5127706
114044838	114044860	10	-	27760321	HT29	viability after 16 days	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	1.102652385643183	[351,274]	[712,901,636]	9	hSpCas9	negative selection	5127707
114044619	114044641	10	-	27760321	HT29	viability after 13 days	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	0.7288719576626811	[585,456]	[1164,850,991]	8	hSpCas9	negative selection	5211166
114044709	114044731	10	-	27760321	HT29	viability after 13 days	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	1.1629255435741102	[412,321]	[970,878,1009]	9	hSpCas9	negative selection	5211167
114044778	114044800	10	+	27760321	HT29	viability after 13 days	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	-0.38889750848251425	[483,377]	[374,412,358]	-4	hSpCas9	negative selection	5211168
114044806	114044828	10	-	27760321	HT29	viability after 13 days	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.1089572152775898	[398,311]	[473,375,481]	1	hSpCas9	negative selection	5211169
114044838	114044860	10	-	27760321	HT29	viability after 13 days	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.9011515126867484	[351,274]	[779,519,733]	9	hSpCas9	negative selection	5211170
114044619	114044641	10	-	27760321	HT29	viability after 10 days	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	0.5043343802543615	[585,456]	[853,663,1237]	7	hSpCas9	negative selection	5294629
114044709	114044731	10	-	27760321	HT29	viability after 10 days	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	0.9739464848067775	[412,321]	[960,864,876]	9	hSpCas9	negative selection	5294630
114044778	114044800	10	+	27760321	HT29	viability after 10 days	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	-0.20697388389875976	[483,377]	[622,403,371]	-3	hSpCas9	negative selection	5294631
114044806	114044828	10	-	27760321	HT29	viability after 10 days	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.3979778456250583	[398,311]	[669,472,607]	5	hSpCas9	negative selection	5294632
114044838	114044860	10	-	27760321	HT29	viability after 10 days	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.7305765961042032	[351,274]	[903,465,574]	8	hSpCas9	negative selection	5294633
114044619	114044641	10	-	27760321	MOLM13	viability	GCAGGCTCTGGTAGCGGAAGGG	ADRB1	ENSG00000043591	0.4390252937987984	[758,585]	[797,265]	3	hSpCas9	negative selection	5378092
114044709	114044731	10	-	27760321	MOLM13	viability	GCCACCAGTGCATGAGGATGGG	ADRB1	ENSG00000043591	1.0050213787838589	[565,412]	[407,668]	7	hSpCas9	negative selection	5378093
114044778	114044800	10	+	27760321	MOLM13	viability	TGCGACTTCGTCACCAACCGGG	ADRB1	ENSG00000043591	-0.6657476118996726	[544,483]	[280,98]	-4	hSpCas9	negative selection	5378094
114044806	114044828	10	-	27760321	MOLM13	viability	GAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.4485733863864299	[401,398]	[365,260]	3	hSpCas9	negative selection	5378095
114044838	114044860	10	-	27760321	MOLM13	viability	CGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	1.3058046059424782	[444,351]	[641,475]	8	hSpCas9	negative selection	5378096
114044244	114044267	10	-	27661255	K562	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	0.07678682589032106	[749,607]	[591,558]	2	dCas9-KRAB	negative selection	5461193
114045037	114045060	10	-	27260156	BXPC3	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.2505777100617068	[841]	[975,812,1172,1271]	5	hSpCas9	negative selection	5527218
114044800	114044823	10	-	27260156	BXPC3	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.1794223616067674	[219]	[252,153,176,226]	-4	hSpCas9	negative selection	5527219
114045037	114045060	10	+	27260156	BXPC3	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.2283453347314197	[138]	[144,108,188,253]	5	hSpCas9	negative selection	5527220
114044164	114044187	10	-	27260156	BXPC3	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.018728737836492315	[699]	[670,715,763,742]	0	hSpCas9	negative selection	5591500
114044468	114044491	10	+	27260156	BXPC3	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.11087689979329389	[491]	[441,476,431,564]	-3	hSpCas9	negative selection	5591501
114044632	114044655	10	+	27260156	BXPC3	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.2583154690670282	[122]	[92,144,253,127]	5	hSpCas9	negative selection	5591502
114045037	114045060	10	-	27260156	A673	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.12803646087210285	[841]	[1078,956,1238,1143]	3	hSpCas9	negative selection	5648469
114044800	114044823	10	-	27260156	A673	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.17724030336174912	[219]	[263,247,184,240]	-4	hSpCas9	negative selection	5648470
114045037	114045060	10	+	27260156	A673	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.3391285980584331	[138]	[203,171,254,212]	7	hSpCas9	negative selection	5648471
114044164	114044187	10	-	27260156	A673	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.054633404413693354	[699]	[1110,754,890,756]	1	hSpCas9	negative selection	5712751
114044468	114044491	10	+	27260156	A673	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.18151868684155997	[491]	[536,415,588,545]	-4	hSpCas9	negative selection	5712752
114044632	114044655	10	+	27260156	A673	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.2574290675696371	[122]	[155,248,164,128]	6	hSpCas9	negative selection	5712753
114045037	114045060	10	-	27260156	A375	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.4044603450909803	[841]	[1544,1201,1458,1017]	6	hSpCas9	negative selection	5769720
114044800	114044823	10	-	27260156	A375	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.3759332302657994	[219]	[246,215,214,124]	-5	hSpCas9	negative selection	5769721
114045037	114045060	10	+	27260156	A375	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.76752041880794	[138]	[146,317,309,327]	9	hSpCas9	negative selection	5769722
114044164	114044187	10	-	27260156	A375	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.27953080635110117	[699]	[1111,1029,1060,792]	4	hSpCas9	negative selection	5834002
114044468	114044491	10	+	27260156	A375	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.0401715836986493	[491]	[492,651,660,565]	0	hSpCas9	negative selection	5834003
114044632	114044655	10	+	27260156	A375	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.35773108440962464	[122]	[88,107,228,285]	5	hSpCas9	negative selection	5834004
114045037	114045060	10	-	27260156	COLO741	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.37376427099306553	[841]	[1597,1416,1195]	7	hSpCas9	negative selection	5890971
114044800	114044823	10	-	27260156	COLO741	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.3757853719320505	[219]	[204,303,144]	-7	hSpCas9	negative selection	5890972
114045037	114045060	10	+	27260156	COLO741	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.7742026512270287	[138]	[405,264,251]	9	hSpCas9	negative selection	5890973
114044164	114044187	10	-	27260156	COLO741	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.17844883294928604	[699]	[743,936,691]	-4	hSpCas9	negative selection	5955253
114044468	114044491	10	+	27260156	COLO741	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.15025868501531892	[491]	[547,434,702]	-3	hSpCas9	negative selection	5955254
114044632	114044655	10	+	27260156	COLO741	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.09446778889853236	[122]	[156,133,207]	2	hSpCas9	negative selection	5955255
114045037	114045060	10	-	27260156	CAL120	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.2514320994510888	[841]	[1484,1266,1028]	4	hSpCas9	negative selection	6012222
114044800	114044823	10	-	27260156	CAL120	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.3615523009852888	[219]	[453,97,124]	-5	hSpCas9	negative selection	6012223
114045037	114045060	10	+	27260156	CAL120	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.4258220012855529	[138]	[173,270,242]	6	hSpCas9	negative selection	6012224
114044164	114044187	10	-	27260156	CAL120	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.09384681891938973	[699]	[1178,773,873]	1	hSpCas9	negative selection	6076504
114044468	114044491	10	+	27260156	CAL120	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.42104013928283723	[491]	[577,477,335]	-6	hSpCas9	negative selection	6076505
114044632	114044655	10	+	27260156	CAL120	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	1.5218146840395357	[122]	[507,399,420]	9	hSpCas9	negative selection	6076506
114045037	114045060	10	-	27260156	CADOES1	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.18182023000711167	[841]	[878,725,850,1104]	3	hSpCas9	negative selection	6133473
114044800	114044823	10	-	27260156	CADOES1	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.29129658877612696	[219]	[115,225,186,138]	-5	hSpCas9	negative selection	6133474
114045037	114045060	10	+	27260156	CADOES1	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.4579203788650321	[138]	[139,229,149,190]	7	hSpCas9	negative selection	6133475
114044164	114044187	10	-	27260156	CADOES1	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.11616404939190128	[699]	[545,547,674,634]	-2	hSpCas9	negative selection	6197755
114044468	114044491	10	+	27260156	CADOES1	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.16834850780264649	[491]	[289,412,519,405]	-3	hSpCas9	negative selection	6197756
114044632	114044655	10	+	27260156	CADOES1	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.10364924215502747	[122]	[82,256,81,67]	1	hSpCas9	negative selection	6197757
114045037	114045060	10	-	27260156	EWS502	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.03471748739194702	[841]	[766,891,936,1085]	0	hSpCas9	negative selection	6254724
114044800	114044823	10	-	27260156	EWS502	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.24705647725460866	[219]	[185,156,203,243]	-4	hSpCas9	negative selection	6254725
114045037	114045060	10	+	27260156	EWS502	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.6175034495103544	[138]	[225,191,203,285]	9	hSpCas9	negative selection	6254726
114044164	114044187	10	-	27260156	EWS502	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.09629949394740689	[699]	[510,1018,715,956]	1	hSpCas9	negative selection	6319006
114044468	114044491	10	+	27260156	EWS502	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.11870821631897474	[491]	[432,531,558,768]	2	hSpCas9	negative selection	6319007
114044632	114044655	10	+	27260156	EWS502	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	-0.6936476881655516	[122]	[65,66,72,120]	-8	hSpCas9	negative selection	6319008
114045037	114045060	10	-	27260156	EW8	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.28130503721524036	[841]	[850,825,721,935]	5	hSpCas9	negative selection	6375975
114044800	114044823	10	-	27260156	EW8	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.2468045628293134	[219]	[185,63,131,224]	-4	hSpCas9	negative selection	6375976
114045037	114045060	10	+	27260156	EW8	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.8656392008528363	[138]	[285,148,247,138]	9	hSpCas9	negative selection	6375977
114044164	114044187	10	-	27260156	EW8	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.21652297371280516	[699]	[820,704,570,570]	4	hSpCas9	negative selection	6440257
114044468	114044491	10	+	27260156	EW8	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.3885625461885981	[491]	[285,312,312,301]	-6	hSpCas9	negative selection	6440258
114044632	114044655	10	+	27260156	EW8	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.12244898451347996	[122]	[119,115,114,82]	2	hSpCas9	negative selection	6440259
114045037	114045060	10	-	27260156	CORL105	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.30602873939804454	[841]	[1141,1183,1382,1188]	6	hSpCas9	negative selection	6497226
114044800	114044823	10	-	27260156	CORL105	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.6453934928996763	[219]	[58,148,234,222]	-8	hSpCas9	negative selection	6497227
114045037	114045060	10	+	27260156	CORL105	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.7597852811937548	[138]	[211,206,508,209]	9	hSpCas9	negative selection	6497228
114044164	114044187	10	-	27260156	CORL105	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.2077789860190805	[699]	[796,897,1337,809]	4	hSpCas9	negative selection	6561508
114044468	114044491	10	+	27260156	CORL105	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.12748953061928095	[491]	[634,546,603,727]	2	hSpCas9	negative selection	6561509
114044632	114044655	10	+	27260156	CORL105	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.8827391255116459	[122]	[221,387,231,210]	9	hSpCas9	negative selection	6561510
114045037	114045060	10	-	27260156	HS294T	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.6783914253680046	[841]	[368,509,419,853]	8	hSpCas9	negative selection	6618477
114044800	114044823	10	-	27260156	HS294T	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	0.8200860216414585	[219]	[98,193,108,211]	9	hSpCas9	negative selection	6618478
114045037	114045060	10	+	27260156	HS294T	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.901659760394864	[138]	[122,37,130,110]	9	hSpCas9	negative selection	6618479
114044164	114044187	10	-	27260156	HS294T	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.3866210962093226	[699]	[117,238,210,278]	-5	hSpCas9	negative selection	6682759
114044468	114044491	10	+	27260156	HS294T	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.14502273934112117	[491]	[187,170,255,232]	2	hSpCas9	negative selection	6682760
114044632	114044655	10	+	27260156	HS294T	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	1.111141153302515	[122]	[194,62,66,72]	9	hSpCas9	negative selection	6682761
114045037	114045060	10	-	27260156	HCC44	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.5925845621724364	[841]	[1145,1528,1843,1249]	8	hSpCas9	negative selection	6739728
114044800	114044823	10	-	27260156	HCC44	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.07239726383329104	[219]	[128,129,557,189]	-1	hSpCas9	negative selection	6739729
114045037	114045060	10	+	27260156	HCC44	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.6269288746077728	[138]	[256,224,223,262]	9	hSpCas9	negative selection	6739730
114044164	114044187	10	-	27260156	HCC44	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.2912548659199953	[699]	[1171,655,822,1244]	5	hSpCas9	negative selection	6804010
114044468	114044491	10	+	27260156	HCC44	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.1359535553805047	[491]	[416,421,754,871]	2	hSpCas9	negative selection	6804011
114044632	114044655	10	+	27260156	HCC44	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.22451904369932607	[122]	[207,86,190,181]	3	hSpCas9	negative selection	6804012
114045037	114045060	10	-	27260156	G402	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.27780160835751966	[841]	[1023,1426,1004,1487]	3	hSpCas9	negative selection	6860979
114044800	114044823	10	-	27260156	G402	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.8693199739591406	[219]	[254,118,181,49]	-8	hSpCas9	negative selection	6860980
114045037	114045060	10	+	27260156	G402	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.33904526879334096	[138]	[195,159,185,304]	4	hSpCas9	negative selection	6860981
114044164	114044187	10	-	27260156	G402	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.03724124903811099	[699]	[1078,1136,583,752]	0	hSpCas9	negative selection	6925261
114044468	114044491	10	+	27260156	G402	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.5205342089802012	[491]	[422,490,296,463]	-6	hSpCas9	negative selection	6925262
114044632	114044655	10	+	27260156	G402	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.09998277363993835	[122]	[131,242,204,67]	1	hSpCas9	negative selection	6925263
114045037	114045060	10	-	27260156	L33	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.36495433050703774	[841]	[1253,402,662,1040]	7	hSpCas9	negative selection	6982230
114044800	114044823	10	-	27260156	L33	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.28269899780347196	[219]	[183,65,116,191]	-6	hSpCas9	negative selection	6982231
114045037	114045060	10	+	27260156	L33	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	1.0750317179058064	[138]	[304,170,150,208]	9	hSpCas9	negative selection	6982232
114044164	114044187	10	-	27260156	L33	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.11512575829760435	[699]	[540,276,435,676]	-3	hSpCas9	negative selection	7046512
114044468	114044491	10	+	27260156	L33	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.09932347573064504	[491]	[441,221,362,548]	2	hSpCas9	negative selection	7046513
114044632	114044655	10	+	27260156	L33	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.09545019728599802	[122]	[79,73,100,105]	2	hSpCas9	negative selection	7046514
114045037	114045060	10	-	27260156	K562	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.7655795638021374	[841]	[1540,1253,898,1388]	8	hSpCas9	negative selection	7103481
114044800	114044823	10	-	27260156	K562	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.32334752907265596	[219]	[90,122,383,32]	-4	hSpCas9	negative selection	7103482
114045037	114045060	10	+	27260156	K562	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.71698973662356	[138]	[152,191,214,240]	8	hSpCas9	negative selection	7103483
114044164	114044187	10	-	27260156	K562	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.3506612723364898	[699]	[1171,427,557,994]	4	hSpCas9	negative selection	7167763
114044468	114044491	10	+	27260156	K562	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.49134407735456	[491]	[223,381,389,248]	-5	hSpCas9	negative selection	7167764
114044632	114044655	10	+	27260156	K562	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	-0.06443699348438159	[122]	[108,76,30,188]	-1	hSpCas9	negative selection	7167765
114045037	114045060	10	-	27260156	HT29	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.2590131356311758	[841]	[1368,1391,1155,1023]	5	hSpCas9	negative selection	7224732
114044800	114044823	10	-	27260156	HT29	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.30033429648892107	[219]	[173,224,279,188]	-5	hSpCas9	negative selection	7224733
114045037	114045060	10	+	27260156	HT29	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.5033046446106046	[138]	[267,235,257,200]	8	hSpCas9	negative selection	7224734
114044164	114044187	10	-	27260156	HT29	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.16668150027352135	[699]	[702,717,820,774]	-3	hSpCas9	negative selection	7289014
114044468	114044491	10	+	27260156	HT29	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.08988593453301494	[491]	[643,490,761,632]	1	hSpCas9	negative selection	7289015
114044632	114044655	10	+	27260156	HT29	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.7238568723077825	[122]	[255,283,266,189]	9	hSpCas9	negative selection	7289016
114045037	114045060	10	-	27260156	MHHES1	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.02629094194541781	[841]	[994,1124,950,822]	0	hSpCas9	negative selection	7345983
114044800	114044823	10	-	27260156	MHHES1	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.09932831730274949	[219]	[332,209,228,171]	-2	hSpCas9	negative selection	7345984
114045037	114045060	10	+	27260156	MHHES1	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	1.0148259025670427	[138]	[381,506,241,184]	9	hSpCas9	negative selection	7345985
114044164	114044187	10	-	27260156	MHHES1	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.027797816756115368	[699]	[728,819,865,681]	0	hSpCas9	negative selection	7410265
114044468	114044491	10	+	27260156	MHHES1	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.013174802683793618	[491]	[909,511,475,367]	0	hSpCas9	negative selection	7410266
114044632	114044655	10	+	27260156	MHHES1	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.48193469623739604	[122]	[151,297,274,77]	8	hSpCas9	negative selection	7410267
114045037	114045060	10	-	27260156	MEWO	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.23877387806941996	[841]	[946,880,963]	5	hSpCas9	negative selection	7467234
114044800	114044823	10	-	27260156	MEWO	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.531342169080864	[219]	[161,141,126]	-8	hSpCas9	negative selection	7467235
114045037	114045060	10	+	27260156	MEWO	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.4721809045277947	[138]	[215,189,141]	8	hSpCas9	negative selection	7467236
114044164	114044187	10	-	27260156	MEWO	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.04732900362745307	[699]	[774,694,578]	1	hSpCas9	negative selection	7531516
114044468	114044491	10	+	27260156	MEWO	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.004580917979604457	[491]	[561,334,499]	0	hSpCas9	negative selection	7531517
114044632	114044655	10	+	27260156	MEWO	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.207928948284555	[122]	[112,102,178]	4	hSpCas9	negative selection	7531518
114045037	114045060	10	-	27260156	LNCAPCLONEFGC	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.42831342035590714	[841]	[1024,926,1144,1031]	6	hSpCas9	negative selection	7588485
114044800	114044823	10	-	27260156	LNCAPCLONEFGC	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.9016859138391682	[219]	[84,91,200,63]	-8	hSpCas9	negative selection	7588486
114045037	114045060	10	+	27260156	LNCAPCLONEFGC	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.6206053082309952	[138]	[211,166,168,223]	8	hSpCas9	negative selection	7588487
114044164	114044187	10	-	27260156	LNCAPCLONEFGC	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.33766290298363744	[699]	[761,705,977,791]	5	hSpCas9	negative selection	7652767
114044468	114044491	10	+	27260156	LNCAPCLONEFGC	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.1295919307414299	[491]	[535,454,526,438]	2	hSpCas9	negative selection	7652768
114044632	114044655	10	+	27260156	LNCAPCLONEFGC	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.4539813278776579	[122]	[214,124,192,83]	7	hSpCas9	negative selection	7652769
114045037	114045060	10	-	27260156	PANC0327	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.48640940607547933	[841]	[1134,951,1221,901]	7	hSpCas9	negative selection	7709736
114044800	114044823	10	-	27260156	PANC0327	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.5512489671020668	[219]	[145,68,248,78]	-7	hSpCas9	negative selection	7709737
114045037	114045060	10	+	27260156	PANC0327	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.8059659324248587	[138]	[291,90,324,177]	9	hSpCas9	negative selection	7709738
114044164	114044187	10	-	27260156	PANC0327	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.4242004265541365	[699]	[1087,895,719,645]	6	hSpCas9	negative selection	7774018
114044468	114044491	10	+	27260156	PANC0327	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.36820665972730027	[491]	[369,319,219,448]	-5	hSpCas9	negative selection	7774019
114044632	114044655	10	+	27260156	PANC0327	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.4856468635335125	[122]	[102,104,176,228]	7	hSpCas9	negative selection	7774020
114045037	114045060	10	-	27260156	NCIH2009	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.41044945951690326	[841]	[1855,1388,1503]	5	hSpCas9	negative selection	7830987
114044800	114044823	10	-	27260156	NCIH2009	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.19982939069223993	[219]	[324,142,347]	-3	hSpCas9	negative selection	7830988
114045037	114045060	10	+	27260156	NCIH2009	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	1.0633262170687234	[138]	[460,445,319]	9	hSpCas9	negative selection	7830989
114044164	114044187	10	-	27260156	NCIH2009	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.06336599300379697	[699]	[1152,894,801]	-1	hSpCas9	negative selection	7895269
114044468	114044491	10	+	27260156	NCIH2009	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.3296170133045587	[491]	[1366,726,597]	4	hSpCas9	negative selection	7895270
114044632	114044655	10	+	27260156	NCIH2009	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.9549632692798173	[122]	[480,281,265]	9	hSpCas9	negative selection	7895271
114045037	114045060	10	-	27260156	NCIH1373	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.44645762794473476	[841]	[1538,1182,1188,335]	4	hSpCas9	negative selection	7952238
114044800	114044823	10	-	27260156	NCIH1373	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.4467229677521576	[219]	[387,159,127,19]	-4	hSpCas9	negative selection	7952239
114045037	114045060	10	+	27260156	NCIH1373	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	1.2336967046628062	[138]	[376,395,481,50]	9	hSpCas9	negative selection	7952240
114044164	114044187	10	-	27260156	NCIH1373	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.06655164195996643	[699]	[773,616,902,186]	0	hSpCas9	negative selection	8016520
114044468	114044491	10	+	27260156	NCIH1373	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.014476072767363846	[491]	[721,437,617,113]	0	hSpCas9	negative selection	8016521
114044632	114044655	10	+	27260156	NCIH1373	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.5267271695174809	[122]	[208,282,118,45]	5	hSpCas9	negative selection	8016522
114045037	114045060	10	-	27260156	PATU8902	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.3628269702410247	[841]	[2086,971,1121,1986]	4	hSpCas9	negative selection	8073489
114044800	114044823	10	-	27260156	PATU8902	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.9731997655245268	[219]	[305,161,112,36]	-7	hSpCas9	negative selection	8073490
114045037	114045060	10	+	27260156	PATU8902	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.9641203253255407	[138]	[574,332,273,345]	9	hSpCas9	negative selection	8073491
114044164	114044187	10	-	27260156	PATU8902	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.6328849535040968	[699]	[1374,1368,1039,2491]	6	hSpCas9	negative selection	8137771
114044468	114044491	10	+	27260156	PATU8902	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.28117735883119044	[491]	[831,481,365,625]	-3	hSpCas9	negative selection	8137772
114044632	114044655	10	+	27260156	PATU8902	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.6221903830879283	[122]	[423,186,233,205]	6	hSpCas9	negative selection	8137773
114045037	114045060	10	-	27260156	PANC1	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.24330065995621375	[841]	[868,1013,974,623]	4	hSpCas9	negative selection	8194740
114044800	114044823	10	-	27260156	PANC1	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-1.0141473942673886	[219]	[75,98,103,94]	-8	hSpCas9	negative selection	8194741
114045037	114045060	10	+	27260156	PANC1	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.5894849897212471	[138]	[138,217,204,164]	8	hSpCas9	negative selection	8194742
114044164	114044187	10	-	27260156	PANC1	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.2801619192956334	[699]	[814,1017,540,609]	4	hSpCas9	negative selection	8259022
114044468	114044491	10	+	27260156	PANC1	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.21402818693097156	[491]	[464,374,330,291]	-3	hSpCas9	negative selection	8259023
114044632	114044655	10	+	27260156	PANC1	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.45159017340281293	[122]	[83,182,186,132]	7	hSpCas9	negative selection	8259024
114045037	114045060	10	-	27260156	PANC0813	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.18054970617053923	[841]	[1223,847,1396,1028]	3	hSpCas9	negative selection	8315991
114044800	114044823	10	-	27260156	PANC0813	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.6210584443383347	[219]	[189,169,235,82]	-7	hSpCas9	negative selection	8315992
114045037	114045060	10	+	27260156	PANC0813	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.7920637223097441	[138]	[263,344,160,353]	9	hSpCas9	negative selection	8315993
114044164	114044187	10	-	27260156	PANC0813	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.1096303546934827	[699]	[986,840,922,809]	1	hSpCas9	negative selection	8380273
114044468	114044491	10	+	27260156	PANC0813	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.05309953134183367	[491]	[807,576,457,414]	-1	hSpCas9	negative selection	8380274
114044632	114044655	10	+	27260156	PANC0813	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	-0.021271310271230304	[122]	[147,108,154,156]	0	hSpCas9	negative selection	8380275
114045037	114045060	10	-	27260156	RDES	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	-0.023829614584985004	[841]	[796,1004,918,1109]	0	hSpCas9	negative selection	8437242
114044800	114044823	10	-	27260156	RDES	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-1.0370101405881103	[219]	[131,121,89,144]	-9	hSpCas9	negative selection	8437243
114045037	114045060	10	+	27260156	RDES	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.7060887786852059	[138]	[195,174,321,386]	9	hSpCas9	negative selection	8437244
114044164	114044187	10	-	27260156	RDES	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.26724206435625975	[699]	[771,912,1029,1219]	4	hSpCas9	negative selection	8501524
114044468	114044491	10	+	27260156	RDES	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.006201836246663879	[491]	[411,539,624,721]	0	hSpCas9	negative selection	8501525
114044632	114044655	10	+	27260156	RDES	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.5901081466860771	[122]	[191,188,277,191]	8	hSpCas9	negative selection	8501526
114045037	114045060	10	-	27260156	PC3	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.4601317914375047	[841]	[707,1183,2276,961]	8	hSpCas9	negative selection	8558493
114044800	114044823	10	-	27260156	PC3	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-1.257897122699821	[219]	[51,99,115,117]	-9	hSpCas9	negative selection	8558494
114045037	114045060	10	+	27260156	PC3	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.5477706668320443	[138]	[132,187,350,206]	9	hSpCas9	negative selection	8558495
114044164	114044187	10	-	27260156	PC3	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.07523393703273379	[699]	[370,771,817,816]	-2	hSpCas9	negative selection	8622775
114044468	114044491	10	+	27260156	PC3	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.3073226552252377	[491]	[225,456,515,470]	-6	hSpCas9	negative selection	8622776
114044632	114044655	10	+	27260156	PC3	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	-0.04403946379445345	[122]	[80,83,309,79]	-1	hSpCas9	negative selection	8622777
114045037	114045060	10	-	27260156	PATU8988T	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.19341791365928973	[841]	[862,1010,678,1200]	3	hSpCas9	negative selection	8679744
114044800	114044823	10	-	27260156	PATU8988T	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.18021177075093164	[219]	[76,215,260,198]	-3	hSpCas9	negative selection	8679745
114045037	114045060	10	+	27260156	PATU8988T	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.5623729066569432	[138]	[140,205,231,215]	8	hSpCas9	negative selection	8679746
114044164	114044187	10	-	27260156	PATU8988T	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.08068620565636753	[699]	[468,780,622,1019]	1	hSpCas9	negative selection	8744026
114044468	114044491	10	+	27260156	PATU8988T	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.09177961153593858	[491]	[397,660,449,534]	1	hSpCas9	negative selection	8744027
114044632	114044655	10	+	27260156	PATU8988T	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.2785735828995075	[122]	[74,230,84,198]	5	hSpCas9	negative selection	8744028
114045037	114045060	10	-	27260156	T47D	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.22796584427307964	[841]	[1148,1197,1064,1180]	5	hSpCas9	negative selection	8800995
114044800	114044823	10	-	27260156	T47D	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.29660010433594874	[219]	[181,239,218,189]	-6	hSpCas9	negative selection	8800996
114045037	114045060	10	+	27260156	T47D	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.7106997851248369	[138]	[228,252,274,304]	9	hSpCas9	negative selection	8800997
114044164	114044187	10	-	27260156	T47D	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.20903710548384202	[699]	[1009,824,1018,924]	4	hSpCas9	negative selection	8865277
114044468	114044491	10	+	27260156	T47D	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.09906257046597305	[491]	[541,395,621,592]	-2	hSpCas9	negative selection	8865278
114044632	114044655	10	+	27260156	T47D	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.20545888140212654	[122]	[183,152,140,184]	4	hSpCas9	negative selection	8865279
114045037	114045060	10	-	27260156	SU8686	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.3058332756168567	[841]	[876,928,985,1420]	5	hSpCas9	negative selection	8922246
114044800	114044823	10	-	27260156	SU8686	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.2533277053580749	[219]	[132,201,177,227]	-4	hSpCas9	negative selection	8922247
114045037	114045060	10	+	27260156	SU8686	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.9179883542738285	[138]	[201,207,271,392]	9	hSpCas9	negative selection	8922248
114044164	114044187	10	-	27260156	SU8686	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.01885324998518567	[699]	[609,547,586,1164]	0	hSpCas9	negative selection	8986528
114044468	114044491	10	+	27260156	SU8686	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.010983925634715078	[491]	[420,451,626,476]	0	hSpCas9	negative selection	8986529
114044632	114044655	10	+	27260156	SU8686	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.36450558008271194	[122]	[220,102,133,169]	6	hSpCas9	negative selection	8986530
114045037	114045060	10	-	27260156	SKES1	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.13999783247320163	[841]	[972,1162,868,744]	3	hSpCas9	negative selection	9043497
114044800	114044823	10	-	27260156	SKES1	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.9587406237352394	[219]	[99,76,124,138]	-9	hSpCas9	negative selection	9043498
114045037	114045060	10	+	27260156	SKES1	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.6574239176595371	[138]	[197,227,177,261]	9	hSpCas9	negative selection	9043499
114044164	114044187	10	-	27260156	SKES1	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.22651387847420434	[699]	[814,767,929,746]	5	hSpCas9	negative selection	9107779
114044468	114044491	10	+	27260156	SKES1	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.18735187067826276	[491]	[448,457,389,428]	-4	hSpCas9	negative selection	9107780
114044632	114044655	10	+	27260156	SKES1	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.05396543941520515	[122]	[205,128,55,128]	1	hSpCas9	negative selection	9107781
114045037	114045060	10	-	27260156	TOV112D	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.2832967078393509	[841]	[972,1339,976,889]	5	hSpCas9	negative selection	9164748
114044800	114044823	10	-	27260156	TOV112D	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.589719791581172	[219]	[238,175,57,127]	-8	hSpCas9	negative selection	9164749
114045037	114045060	10	+	27260156	TOV112D	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.8194462194737357	[138]	[266,334,227,177]	9	hSpCas9	negative selection	9164750
114044164	114044187	10	-	27260156	TOV112D	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.1638880676005544	[699]	[812,1369,477,629]	3	hSpCas9	negative selection	9229030
114044468	114044491	10	+	27260156	TOV112D	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	0.03387021823438151	[491]	[505,649,501,397]	0	hSpCas9	negative selection	9229031
114044632	114044655	10	+	27260156	TOV112D	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.7793056239857052	[122]	[241,84,247,240]	9	hSpCas9	negative selection	9229032
114045037	114045060	10	-	27260156	TC71	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.05647758743661169	[841]	[977,976,871,927]	1	hSpCas9	negative selection	9285999
114044800	114044823	10	-	27260156	TC71	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.3050301221747955	[219]	[171,199,186,205]	-7	hSpCas9	negative selection	9286000
114045037	114045060	10	+	27260156	TC71	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.4314506842050454	[138]	[187,160,215,240]	8	hSpCas9	negative selection	9286001
114044164	114044187	10	-	27260156	TC71	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	-0.01959763623653299	[699]	[705,634,827,792]	0	hSpCas9	negative selection	9350281
114044468	114044491	10	+	27260156	TC71	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.21475611862813576	[491]	[542,487,271,522]	-5	hSpCas9	negative selection	9350282
114044632	114044655	10	+	27260156	TC71	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	-0.0713540994948989	[122]	[113,148,69,173]	-2	hSpCas9	negative selection	9350283
114045037	114045060	10	-	27260156	TC32	viability	CCGCTTACCCGCACGCCCGTTGG	ADRB1	ENSG00000043591	0.027581140655709935	[841]	[670,609,1206,854]	0	hSpCas9	negative selection	9407250
114044800	114044823	10	-	27260156	TC32	viability	TACGGACGAGGCGATGGCGTAGG	ADRB1	ENSG00000043591	-0.27178833143625813	[219]	[183,154,234,111]	-5	hSpCas9	negative selection	9407251
114045037	114045060	10	+	27260156	TC32	viability	CCAACGGGCGTGCGGGTAAGCGG	ADRB1	ENSG00000043591	0.6353473392574196	[138]	[244,146,165,252]	9	hSpCas9	negative selection	9407252
114044164	114044187	10	-	27260156	TC32	viability	CGACGACAGGTTACCGGGCTCGG	ADRB1	ENSG00000043591	0.06769469645192217	[699]	[751,480,751,819]	1	hSpCas9	negative selection	9471532
114044468	114044491	10	+	27260156	TC32	viability	GCCGTTCGGGGCCACCATCGTGG	ADRB1	ENSG00000043591	-0.5463785920039038	[491]	[281,200,368,461]	-8	hSpCas9	negative selection	9471533
114044632	114044655	10	+	27260156	TC32	viability	AGAGCCTGCTGACGCGCGCGCGG	ADRB1	ENSG00000043591	0.6617052830273147	[122]	[207,207,143,135]	9	hSpCas9	negative selection	9471534
114044498	114044521	10	-	27869803	HPAFII	viability after 27 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.29511771985812485	[142]	[9,103,NaN]	-2	hSpCas9	negative selection	9536756
114044515	114044538	10	-	27869803	HPAFII	viability after 27 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.616209059714001	[228]	[183,184,NaN]	5	hSpCas9	negative selection	9536757
114044620	114044643	10	-	27869803	HPAFII	viability after 27 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.03371962141361723	[213]	[92,123,NaN]	0	hSpCas9	negative selection	9536758
114044838	114044861	10	-	27869803	HPAFII	viability after 27 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.039478271478488924	[739]	[455,313,NaN]	0	hSpCas9	negative selection	9536759
114044840	114044863	10	-	27869803	HPAFII	viability after 27 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	0.26098114203830924	[270]	[23,292,NaN]	2	hSpCas9	negative selection	9536760
114045299	114045322	10	+	27869803	HPAFII	viability after 27 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	-2.041800310565905	[88]	[0,19,NaN]	-8	hSpCas9	negative selection	9536761
114044498	114044521	10	-	27869803	HPAFII	viability after 15 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	0.6548280143620263	[142]	[257,231,NaN]	7	hSpCas9	negative selection	9619205
114044515	114044538	10	-	27869803	HPAFII	viability after 15 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.19161103992765569	[228]	[322,254,NaN]	2	hSpCas9	negative selection	9619206
114044620	114044643	10	-	27869803	HPAFII	viability after 15 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.013076789262716382	[213]	[230,225,NaN]	0	hSpCas9	negative selection	9619207
114044838	114044861	10	-	27869803	HPAFII	viability after 15 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.3007350090274341	[739]	[702,609,NaN]	-3	hSpCas9	negative selection	9619208
114044840	114044863	10	-	27869803	HPAFII	viability after 15 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	0.465093212897248	[270]	[184,536,NaN]	5	hSpCas9	negative selection	9619209
114045299	114045322	10	+	27869803	HPAFII	viability after 15 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	-2.6857898547836587	[88]	[4,20,NaN]	-9	hSpCas9	negative selection	9619210
114044498	114044521	10	-	27869803	ASPC1	viability after 36 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.9380821086361308	[681]	[301,82,30]	-7	hSpCas9	negative selection	9701654
114044515	114044538	10	-	27869803	ASPC1	viability after 36 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	0.8562272365593078	[693]	[780,543,109]	8	hSpCas9	negative selection	9701655
114044620	114044643	10	-	27869803	ASPC1	viability after 36 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.22430974908244922	[462]	[253,1,163]	-2	hSpCas9	negative selection	9701656
114044838	114044861	10	-	27869803	ASPC1	viability after 36 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	1.2553091164803727	[1530]	[856,916,1840]	9	hSpCas9	negative selection	9701657
114044840	114044863	10	-	27869803	ASPC1	viability after 36 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.1315591595373708	[899]	[324,190,332]	-1	hSpCas9	negative selection	9701658
114045299	114045322	10	+	27869803	ASPC1	viability after 36 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	-0.5324751934476835	[70]	[0,19,25]	-5	hSpCas9	negative selection	9701659
114044498	114044521	10	-	27869803	PATU8988S	viability after 35 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-1.4655210633954918	[482]	[43,96,NaN]	-8	hSpCas9	negative selection	9784103
114044515	114044538	10	-	27869803	PATU8988S	viability after 35 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	-0.3832806781009116	[624]	[188,196,NaN]	-4	hSpCas9	negative selection	9784104
114044620	114044643	10	-	27869803	PATU8988S	viability after 35 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.19766052357144775	[465]	[229,96,NaN]	-2	hSpCas9	negative selection	9784105
114044838	114044861	10	-	27869803	PATU8988S	viability after 35 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.4434155157481128	[1752]	[986,932,NaN]	5	hSpCas9	negative selection	9784106
114044840	114044863	10	-	27869803	PATU8988S	viability after 35 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.17178898448765856	[709]	[188,318,NaN]	-2	hSpCas9	negative selection	9784107
114045299	114045322	10	+	27869803	PATU8988S	viability after 35 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	1.3288052741020322	[91]	[125,59,NaN]	9	hSpCas9	negative selection	9784108
114044498	114044521	10	-	27869803	PATU8988S	viability after 31 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-1.3084626048817873	[482]	[75,79,NaN]	-8	hSpCas9	negative selection	9866552
114044515	114044538	10	-	27869803	PATU8988S	viability after 31 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	-0.3605062966249981	[624]	[150,248,NaN]	-4	hSpCas9	negative selection	9866553
114044620	114044643	10	-	27869803	PATU8988S	viability after 31 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	0.653449397726034	[465]	[253,340,NaN]	7	hSpCas9	negative selection	9866554
114044838	114044861	10	-	27869803	PATU8988S	viability after 31 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.49943935104695103	[1752]	[926,1065,NaN]	6	hSpCas9	negative selection	9866555
114044840	114044863	10	-	27869803	PATU8988S	viability after 31 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.08792231341721723	[709]	[118,453,NaN]	-1	hSpCas9	negative selection	9866556
114045299	114045322	10	+	27869803	PATU8988S	viability after 31 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	0.903871444550346	[91]	[65,71,NaN]	8	hSpCas9	negative selection	9866557
114044498	114044521	10	-	27869803	HPAFII	viability after 35 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	-0.19112003162083568	[142]	[61,64,NaN]	-1	hSpCas9	negative selection	9949001
114044515	114044538	10	-	27869803	HPAFII	viability after 35 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	-0.05373706974624809	[228]	[82,143,NaN]	0	hSpCas9	negative selection	9949002
114044620	114044643	10	-	27869803	HPAFII	viability after 35 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.281276307334609	[213]	[27,157,NaN]	-2	hSpCas9	negative selection	9949003
114044838	114044861	10	-	27869803	HPAFII	viability after 35 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	0.4816903856819166	[739]	[397,663,NaN]	3	hSpCas9	negative selection	9949004
114044840	114044863	10	-	27869803	HPAFII	viability after 35 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	-0.008118199218898295	[270]	[39,244,NaN]	0	hSpCas9	negative selection	9949005
114045299	114045322	10	+	27869803	HPAFII	viability after 35 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	-2.570499456468653	[88]	[0,14,NaN]	-8	hSpCas9	negative selection	9949006
114044498	114044521	10	-	27869803	HPAFII	viability after 31 days	AGAAGGAGCCGTACTCCCAGCGG	ADRB1	ENSG00000043591	0.3059758248206566	[142]	[36,166,NaN]	2	hSpCas9	negative selection	10031450
114044515	114044538	10	-	27869803	HPAFII	viability after 31 days	GGTCCACAGCTCGCAGAAGAAGG	ADRB1	ENSG00000043591	-0.04839883563396011	[228]	[96,153,NaN]	0	hSpCas9	negative selection	10031451
114044620	114044643	10	-	27869803	HPAFII	viability after 31 days	CAGCAGGCTCTGGTAGCGGAAGG	ADRB1	ENSG00000043591	-0.2001451033317685	[213]	[71,139,NaN]	-1	hSpCas9	negative selection	10031452
114044838	114044861	10	-	27869803	HPAFII	viability after 31 days	ACGAAGGCCATGATGCACAGGGG	ADRB1	ENSG00000043591	-0.04711238330275247	[739]	[333,475,NaN]	0	hSpCas9	negative selection	10031453
114044840	114044863	10	-	27869803	HPAFII	viability after 31 days	ACACGAAGGCCATGATGCACAGG	ADRB1	ENSG00000043591	0.30920545931022314	[270]	[41,347,NaN]	2	hSpCas9	negative selection	10031454
114045299	114045322	10	+	27869803	HPAFII	viability after 31 days	ACTGCTCTGCTGCGCGCGCAGGG	ADRB1	ENSG00000043591	-2.1152203849583264	[88]	[0,22,NaN]	-8	hSpCas9	negative selection	10031455
114044244	114044267	10	-	28162770	P31FUJ	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-0.5953722837990871	[107]	[83]	-5	hSpCas9	negative selection	10107734
114045235	114045258	10	-	28162770	P31FUJ	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	0.047305714778356656	[13]	[16]	0	hSpCas9	negative selection	10107735
114044377	114044400	10	-	28162770	P31FUJ	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.5613370981390617	[281]	[488]	6	hSpCas9	negative selection	10107736
114044482	114044505	10	-	28162770	P31FUJ	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.3427819639909162	[462]	[689]	4	hSpCas9	negative selection	10107737
114044608	114044631	10	-	28162770	P31FUJ	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.5168744415013816	[225]	[379]	6	hSpCas9	negative selection	10107738
114044692	114044715	10	-	28162770	P31FUJ	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-1.0728612915446885	[144]	[80]	-6	hSpCas9	negative selection	10107739
114044806	114044829	10	-	28162770	P31FUJ	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	-0.020826399023269104	[277]	[321]	0	hSpCas9	negative selection	10107740
114044854	114044877	10	-	28162770	P31FUJ	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-0.42544728235677454	[127]	[111]	-4	hSpCas9	negative selection	10107741
114045040	114045063	10	+	28162770	P31FUJ	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	1.5113588911560314	[19]	[66]	9	hSpCas9	negative selection	10107742
114045200	114045223	10	-	28162770	P31FUJ	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.2200567602994323	[159]	[218]	2	hSpCas9	negative selection	10107743
114044244	114044267	10	-	28162770	TF1	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10277100
114045235	114045258	10	-	28162770	TF1	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10277101
114044377	114044400	10	-	28162770	TF1	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10277102
114044482	114044505	10	-	28162770	TF1	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	NaN	[NaN]	[333]	1	hSpCas9	negative selection	10277103
114044608	114044631	10	-	28162770	TF1	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10277104
114044692	114044715	10	-	28162770	TF1	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10277105
114044806	114044829	10	-	28162770	TF1	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	NaN	[NaN]	[272]	1	hSpCas9	negative selection	10277106
114044854	114044877	10	-	28162770	TF1	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	NaN	[NaN]	[124]	1	hSpCas9	negative selection	10277107
114045040	114045063	10	+	28162770	TF1	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10277108
114045200	114045223	10	-	28162770	TF1	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	NaN	[NaN]	[208]	1	hSpCas9	negative selection	10277109
114044244	114044267	10	-	28162770	SKM1	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-1.059040895322855	[32]	[27]	-6	hSpCas9	negative selection	10446466
114045235	114045258	10	-	28162770	SKM1	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	1.499926396865357	[0]	[4]	9	hSpCas9	negative selection	10446467
114044377	114044400	10	-	28162770	SKM1	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.4085300681244588	[100]	[236]	4	hSpCas9	negative selection	10446468
114044482	114044505	10	-	28162770	SKM1	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.03239297973109512	[124]	[225]	0	hSpCas9	negative selection	10446469
114044608	114044631	10	-	28162770	SKM1	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	-0.7704713973819233	[109]	[113]	-5	hSpCas9	negative selection	10446470
114044692	114044715	10	-	28162770	SKM1	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-0.4283378495357286	[50]	[66]	-4	hSpCas9	negative selection	10446471
114044806	114044829	10	-	28162770	SKM1	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.24726096441510842	[60]	[127]	2	hSpCas9	negative selection	10446472
114044854	114044877	10	-	28162770	SKM1	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-0.5937327103488882	[34]	[40]	-5	hSpCas9	negative selection	10446473
114045040	114045063	10	+	28162770	SKM1	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-3.4069641987431614	[5]	[0]	-9	hSpCas9	negative selection	10446474
114045200	114045223	10	-	28162770	SKM1	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.48056107199842585	[29]	[73]	4	hSpCas9	negative selection	10446475
114044244	114044267	10	-	28162770	SKM1	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-1.059040895322855	[32]	[27]	-6	hSpCas9	negative selection	10615832
114045235	114045258	10	-	28162770	SKM1	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	1.499926396865357	[0]	[4]	9	hSpCas9	negative selection	10615833
114044377	114044400	10	-	28162770	SKM1	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.4085300681244588	[100]	[236]	4	hSpCas9	negative selection	10615834
114044482	114044505	10	-	28162770	SKM1	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.03239297973109512	[124]	[225]	0	hSpCas9	negative selection	10615835
114044608	114044631	10	-	28162770	SKM1	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	-0.7704713973819233	[109]	[113]	-5	hSpCas9	negative selection	10615836
114044692	114044715	10	-	28162770	SKM1	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-0.4283378495357286	[50]	[66]	-4	hSpCas9	negative selection	10615837
114044806	114044829	10	-	28162770	SKM1	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.24726096441510842	[60]	[127]	2	hSpCas9	negative selection	10615838
114044854	114044877	10	-	28162770	SKM1	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-0.5937327103488882	[34]	[40]	-5	hSpCas9	negative selection	10615839
114045040	114045063	10	+	28162770	SKM1	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-3.4069641987431614	[5]	[0]	-9	hSpCas9	negative selection	10615840
114045200	114045223	10	-	28162770	SKM1	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.48056107199842585	[29]	[73]	4	hSpCas9	negative selection	10615841
114044244	114044267	10	-	28162770	PL21	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	0.1378553362349776	[141]	[67]	1	hSpCas9	negative selection	10785198
114045235	114045258	10	-	28162770	PL21	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-2.2592920041479774	[10]	[0]	-8	hSpCas9	negative selection	10785199
114044377	114044400	10	-	28162770	PL21	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	-0.6343174516234593	[402]	[112]	-4	hSpCas9	negative selection	10785200
114044482	114044505	10	-	28162770	PL21	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.6739160819206362	[372]	[258]	6	hSpCas9	negative selection	10785201
114044608	114044631	10	-	28162770	PL21	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	-1.1954455221233513	[220]	[41]	-7	hSpCas9	negative selection	10785202
114044692	114044715	10	-	28162770	PL21	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-0.7650949673500034	[163]	[41]	-5	hSpCas9	negative selection	10785203
114044806	114044829	10	-	28162770	PL21	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.8238716853750516	[256]	[197]	7	hSpCas9	negative selection	10785204
114044854	114044877	10	-	28162770	PL21	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	0.2615401591534634	[91]	[47]	2	hSpCas9	negative selection	10785205
114045040	114045063	10	+	28162770	PL21	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-1.1217884803980427	[4]	[0]	-6	hSpCas9	negative selection	10785206
114045200	114045223	10	-	28162770	PL21	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.3435037896604973	[133]	[73]	3	hSpCas9	negative selection	10785207
114044244	114044267	10	-	28162770	P31FUJ	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-0.5953722837990871	[107]	[83]	-5	hSpCas9	negative selection	10954564
114045235	114045258	10	-	28162770	P31FUJ	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	0.047305714778356656	[13]	[16]	0	hSpCas9	negative selection	10954565
114044377	114044400	10	-	28162770	P31FUJ	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.5613370981390617	[281]	[488]	6	hSpCas9	negative selection	10954566
114044482	114044505	10	-	28162770	P31FUJ	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.3427819639909162	[462]	[689]	4	hSpCas9	negative selection	10954567
114044608	114044631	10	-	28162770	P31FUJ	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.5168744415013816	[225]	[379]	6	hSpCas9	negative selection	10954568
114044692	114044715	10	-	28162770	P31FUJ	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-1.0728612915446885	[144]	[80]	-6	hSpCas9	negative selection	10954569
114044806	114044829	10	-	28162770	P31FUJ	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	-0.020826399023269104	[277]	[321]	0	hSpCas9	negative selection	10954570
114044854	114044877	10	-	28162770	P31FUJ	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-0.42544728235677454	[127]	[111]	-4	hSpCas9	negative selection	10954571
114045040	114045063	10	+	28162770	P31FUJ	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	1.5113588911560314	[19]	[66]	9	hSpCas9	negative selection	10954572
114045200	114045223	10	-	28162770	P31FUJ	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.2200567602994323	[159]	[218]	2	hSpCas9	negative selection	10954573
114044244	114044267	10	-	28162770	OCIAML5	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-0.8520665708639972	[46]	[46]	-5	hSpCas9	negative selection	11123930
114045235	114045258	10	-	28162770	OCIAML5	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	1.1479334291360033	[0]	[3]	8	hSpCas9	negative selection	11123931
114044377	114044400	10	-	28162770	OCIAML5	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	1.121077937309297	[121]	[478]	8	hSpCas9	negative selection	11123932
114044482	114044505	10	-	28162770	OCIAML5	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.32368750938051294	[246]	[557]	2	hSpCas9	negative selection	11123933
114044608	114044631	10	-	28162770	OCIAML5	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.30443791481599364	[143]	[320]	2	hSpCas9	negative selection	11123934
114044692	114044715	10	-	28162770	OCIAML5	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-1.7083310934025475	[104]	[57]	-7	hSpCas9	negative selection	11123935
114044806	114044829	10	-	28162770	OCIAML5	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.6445008139114452	[128]	[363]	5	hSpCas9	negative selection	11123936
114044854	114044877	10	-	28162770	OCIAML5	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-0.744263281329482	[115]	[124]	-5	hSpCas9	negative selection	11123937
114045040	114045063	10	+	28162770	OCIAML5	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-3.1739946657513594	[14]	[2]	-9	hSpCas9	negative selection	11123938
114045200	114045223	10	-	28162770	OCIAML5	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.7678297199665463	[67]	[208]	6	hSpCas9	negative selection	11123939
114044244	114044267	10	-	28162770	EOL1	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-1.2481867634586021	[256]	[56]	-7	hSpCas9	negative selection	11293296
114045235	114045258	10	-	28162770	EOL1	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-2.660414729150622	[11]	[0]	-9	hSpCas9	negative selection	11293297
114044377	114044400	10	-	28162770	EOL1	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.3920526907435138	[566]	[391]	3	hSpCas9	negative selection	11293298
114044482	114044505	10	-	28162770	EOL1	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.3683989683541149	[693]	[471]	3	hSpCas9	negative selection	11293299
114044608	114044631	10	-	28162770	EOL1	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.6320634545756543	[484]	[395]	5	hSpCas9	negative selection	11293300
114044692	114044715	10	-	28162770	EOL1	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-0.7527466099226967	[370]	[115]	-5	hSpCas9	negative selection	11293301
114044806	114044829	10	-	28162770	EOL1	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	-0.8362645645500393	[304]	[89]	-5	hSpCas9	negative selection	11293302
114044854	114044877	10	-	28162770	EOL1	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-0.5746848551247377	[146]	[51]	-4	hSpCas9	negative selection	11293303
114045040	114045063	10	+	28162770	EOL1	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	0.23649177788527487	[28]	[17]	2	hSpCas9	negative selection	11293304
114045200	114045223	10	-	28162770	EOL1	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.4710361244770548	[151]	[110]	4	hSpCas9	negative selection	11293305
114044244	114044267	10	-	28162770	MOLM13	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-1.9650700257315277	[161]	[29]	-7	hSpCas9	negative selection	11462662
114045235	114045258	10	-	28162770	MOLM13	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-4.390091613582994	[28]	[0]	-9	hSpCas9	negative selection	11462663
114044377	114044400	10	-	28162770	MOLM13	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	1.633250857844648	[386]	[867]	9	hSpCas9	negative selection	11462664
114044482	114044505	10	-	28162770	MOLM13	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.5201913832145018	[622]	[645]	4	hSpCas9	negative selection	11462665
114044608	114044631	10	-	28162770	MOLM13	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.7057232332532302	[384]	[453]	5	hSpCas9	negative selection	11462666
114044692	114044715	10	-	28162770	MOLM13	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-1.7830721919886399	[237]	[49]	-7	hSpCas9	negative selection	11462667
114044806	114044829	10	-	28162770	MOLM13	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.9605933744137466	[338]	[476]	7	hSpCas9	negative selection	11462668
114044854	114044877	10	-	28162770	MOLM13	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-1.1331927845398544	[269]	[88]	-5	hSpCas9	negative selection	11462669
114045040	114045063	10	+	28162770	MOLM13	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-0.8122185376481568	[16]	[6]	-4	hSpCas9	negative selection	11462670
114045200	114045223	10	-	28162770	MOLM13	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	-1.4914686339580754	[139]	[35]	-6	hSpCas9	negative selection	11462671
114044244	114044267	10	-	28162770	HEL	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	0.23393328643302774	[153]	[115]	2	hSpCas9	negative selection	11632028
114045235	114045258	10	-	28162770	HEL	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	1.9422991138592645	[12]	[31]	9	hSpCas9	negative selection	11632029
114044377	114044400	10	-	28162770	HEL	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.7213208559760375	[392]	[414]	6	hSpCas9	negative selection	11632030
114044482	114044505	10	-	28162770	HEL	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.6703775133226368	[516]	[526]	6	hSpCas9	negative selection	11632031
114044608	114044631	10	-	28162770	HEL	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.4591137593820821	[409]	[360]	4	hSpCas9	negative selection	11632032
114044692	114044715	10	-	28162770	HEL	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	0.2719011366320481	[149]	[115]	2	hSpCas9	negative selection	11632033
114044806	114044829	10	-	28162770	HEL	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	-0.6948425271984907	[277]	[109]	-4	hSpCas9	negative selection	11632034
114044854	114044877	10	-	28162770	HEL	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-2.3572611679996434	[183]	[22]	-8	hSpCas9	negative selection	11632035
114045040	114045063	10	+	28162770	HEL	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	1.684559007694984	[16]	[34]	9	hSpCas9	negative selection	11632036
114045200	114045223	10	-	28162770	HEL	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	-1.3672452565722648	[144]	[35]	-7	hSpCas9	negative selection	11632037
114044244	114044267	10	-	28162770	MV411	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-0.6810091881921905	[117]	[61]	-5	hSpCas9	negative selection	11801394
114045235	114045258	10	-	28162770	MV411	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-1.7525624492172245	[7]	[1]	-8	hSpCas9	negative selection	11801395
114044377	114044400	10	-	28162770	MV411	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.3994406442278253	[341]	[379]	3	hSpCas9	negative selection	11801396
114044482	114044505	10	-	28162770	MV411	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.824905514957007	[385]	[575]	7	hSpCas9	negative selection	11801397
114044608	114044631	10	-	28162770	MV411	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.09602584699179006	[270]	[243]	0	hSpCas9	negative selection	11801398
114044692	114044715	10	-	28162770	MV411	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-1.0122062658502444	[169]	[70]	-6	hSpCas9	negative selection	11801399
114044806	114044829	10	-	28162770	MV411	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.07128059562894838	[173]	[153]	0	hSpCas9	negative selection	11801400
114044854	114044877	10	-	28162770	MV411	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	0.8995142473624684	[83]	[131]	7	hSpCas9	negative selection	11801401
114045040	114045063	10	+	28162770	MV411	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	0.7068691694200724	[23]	[32]	6	hSpCas9	negative selection	11801402
114045200	114045223	10	-	28162770	MV411	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	1.278688484767215	[136]	[279]	9	hSpCas9	negative selection	11801403
114044244	114044267	10	-	28162770	MONOMAC1	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-0.7313732747107421	[83]	[57]	-5	hSpCas9	negative selection	11970760
114045235	114045258	10	-	28162770	MONOMAC1	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-3.656468465696851	[10]	[0]	-9	hSpCas9	negative selection	11970761
114044377	114044400	10	-	28162770	MONOMAC1	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.43063010461584095	[232]	[359]	4	hSpCas9	negative selection	11970762
114044482	114044505	10	-	28162770	MONOMAC1	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	1.01953824768158	[283]	[659]	8	hSpCas9	negative selection	11970763
114044608	114044631	10	-	28162770	MONOMAC1	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	-0.16206070881657897	[162]	[166]	-1	hSpCas9	negative selection	11970764
114044692	114044715	10	-	28162770	MONOMAC1	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-1.1548086116702563	[100]	[51]	-7	hSpCas9	negative selection	11970765
114044806	114044829	10	-	28162770	MONOMAC1	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.6785722907032563	[114]	[210]	6	hSpCas9	negative selection	11970766
114044854	114044877	10	-	28162770	MONOMAC1	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	1.2962951781960343	[64]	[182]	9	hSpCas9	negative selection	11970767
114045040	114045063	10	+	28162770	MONOMAC1	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-1.1970368470595538	[5]	[2]	-7	hSpCas9	negative selection	11970768
114045200	114045223	10	-	28162770	MONOMAC1	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.6839104812966829	[100]	[185]	6	hSpCas9	negative selection	11970769
114044244	114044267	10	-	28162770	OCIAML2	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-1.803205164329032	[33]	[53]	-8	hSpCas9	negative selection	12140126
114045235	114045258	10	-	28162770	OCIAML2	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-0.6632749031845577	[1]	[6]	-5	hSpCas9	negative selection	12140127
114044377	114044400	10	-	28162770	OCIAML2	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.3853598720663195	[49]	[361]	4	hSpCas9	negative selection	12140128
114044482	114044505	10	-	28162770	OCIAML2	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	0.978128291880684	[73]	[807]	8	hSpCas9	negative selection	12140129
114044608	114044631	10	-	28162770	OCIAML2	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	-0.4055347970202765	[64]	[271]	-3	hSpCas9	negative selection	12140130
114044692	114044715	10	-	28162770	OCIAML2	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	0.22239242133644802	[29]	[193]	2	hSpCas9	negative selection	12140131
114044806	114044829	10	-	28162770	OCIAML2	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	-0.5062537349728827	[40]	[159]	-4	hSpCas9	negative selection	12140132
114044854	114044877	10	-	28162770	OCIAML2	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-0.47062982524216124	[15]	[63]	-4	hSpCas9	negative selection	12140133
114045040	114045063	10	+	28162770	OCIAML2	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-0.7701901071010693	[3]	[12]	-5	hSpCas9	negative selection	12140134
114045200	114045223	10	-	28162770	OCIAML2	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	-0.18522760637991298	[23]	[116]	-1	hSpCas9	negative selection	12140135
114044244	114044267	10	-	28162770	OCIAML3	viability	GGAGGCAGCAACGAGGCGGGCGG	ADRB1	ENSG00000043591	-0.6287730584848399	[41]	[81]	-5	hSpCas9	negative selection	12309492
114045235	114045258	10	-	28162770	OCIAML3	viability	GATGGGGTTGAAGGCCGAGTTGG	ADRB1	ENSG00000043591	-2.5940076403241634	[7]	[3]	-9	hSpCas9	negative selection	12309493
114044377	114044400	10	-	28162770	OCIAML3	viability	CAGCCGCGGCGTCTTGGCGATGG	ADRB1	ENSG00000043591	0.6663820442540669	[90]	[435]	6	hSpCas9	negative selection	12309494
114044482	114044505	10	-	28162770	OCIAML3	viability	CCAGCGGCCCCACACCACGATGG	ADRB1	ENSG00000043591	-0.033292685849684256	[139]	[412]	0	hSpCas9	negative selection	12309495
114044608	114044631	10	-	28162770	OCIAML3	viability	GTAGCGGAAGGGCGAGGTGATGG	ADRB1	ENSG00000043591	0.701846942953306	[66]	[328]	6	hSpCas9	negative selection	12309496
114044692	114044715	10	-	28162770	OCIAML3	viability	GATGGGCAGGAAGGACACCAGGG	ADRB1	ENSG00000043591	-0.5648612946646467	[48]	[99]	-4	hSpCas9	negative selection	12309497
114044806	114044829	10	-	28162770	OCIAML3	viability	GGAGACTACGGACGAGGCGATGG	ADRB1	ENSG00000043591	0.017067700716124512	[72]	[222]	0	hSpCas9	negative selection	12309498
114044854	114044877	10	-	28162770	OCIAML3	viability	GAACACCCGCAGGTACACGAAGG	ADRB1	ENSG00000043591	-0.33097323449036953	[24]	[59]	-3	hSpCas9	negative selection	12309499
114045040	114045063	10	+	28162770	OCIAML3	viability	ACGGGCGTGCGGGTAAGCGGCGG	ADRB1	ENSG00000043591	-1.5940076403241639	[2]	[2]	-8	hSpCas9	negative selection	12309500
114045200	114045223	10	-	28162770	OCIAML3	viability	AGTTGAAGAAGACGAAGAGGCGG	ADRB1	ENSG00000043591	0.3694664836507227	[39]	[155]	3	hSpCas9	negative selection	12309501