Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:154
• Symbol:ADRB2
• Description:adrenoceptor beta 2

DataSource: http://genomecrispr.dkfz.de/#!/results/ADRB2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
148827197	148827220	5	+	26472758	Jiyoye	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	-0.07281755961374026	[211]	[151]	0	hSpCas9	negative selection	3489
148827882	148827905	5	+	26472758	Jiyoye	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	-1.390780842549481	[152]	[43]	-7	hSpCas9	negative selection	3490
148827430	148827453	5	-	26472758	Jiyoye	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	1.4674758917736876	[81]	[170]	8	hSpCas9	negative selection	3491
148827442	148827465	5	-	26472758	Jiyoye	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	-0.10183826598198431	[36]	[25]	0	hSpCas9	negative selection	3492
148827679	148827702	5	-	26472758	Jiyoye	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.7837387329700815	[113]	[147]	5	hSpCas9	negative selection	3493
148826888	148826911	5	+	26472758	Jiyoye	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.5798147676452219	[235]	[265]	4	hSpCas9	negative selection	3494
148827001	148827024	5	-	26472758	Jiyoye	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.059252078085566595	[153]	[120]	0	hSpCas9	negative selection	3495
148827317	148827340	5	-	26472758	Jiyoye	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.05784112927785928	[92]	[72]	0	hSpCas9	negative selection	3496
148827462	148827485	5	-	26472758	Jiyoye	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	-0.08615664374971449	[182]	[129]	0	hSpCas9	negative selection	3497
148827545	148827568	5	-	26472758	Jiyoye	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	0.8442391871147161	[64]	[87]	6	hSpCas9	negative selection	3498
148827197	148827220	5	+	26472758	KBM7	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	0.7356197525350195	[789,555]	[725,335]	7	hSpCas9	negative selection	194607
148827882	148827905	5	+	26472758	KBM7	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	0.3914389490423659	[315,284]	[170,197]	4	hSpCas9	negative selection	194608
148827430	148827453	5	-	26472758	KBM7	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.12937391229665152	[1077,957]	[510,370]	-1	hSpCas9	negative selection	194609
148827442	148827465	5	-	26472758	KBM7	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	0.45633486186564065	[137,119]	[72,91]	5	hSpCas9	negative selection	194610
148827679	148827702	5	-	26472758	KBM7	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	-0.026460474625162878	[499,354]	[196,192]	0	hSpCas9	negative selection	194611
148826888	148826911	5	+	26472758	KBM7	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.879179119984928	[904,951]	[1035,605]	8	hSpCas9	negative selection	194612
148827001	148827024	5	-	26472758	KBM7	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.4328543165492107	[442,403]	[252,282]	4	hSpCas9	negative selection	194613
148827317	148827340	5	-	26472758	KBM7	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.4001969849860024	[620,505]	[324,367]	4	hSpCas9	negative selection	194614
148827462	148827485	5	-	26472758	KBM7	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.024874919642948967	[748,812]	[263,477]	0	hSpCas9	negative selection	194615
148827545	148827568	5	-	26472758	KBM7	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	-0.049701618796173685	[793,575]	[361,258]	0	hSpCas9	negative selection	194616
148827197	148827220	5	+	26472758	Raji	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	0.15073990456798148	[294]	[75]	1	hSpCas9	negative selection	385725
148827882	148827905	5	+	26472758	Raji	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	0.9463916587012948	[160]	[71]	8	hSpCas9	negative selection	385726
148827430	148827453	5	-	26472758	Raji	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.6150824890974917	[395]	[59]	-5	hSpCas9	negative selection	385727
148827442	148827465	5	-	26472758	Raji	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	2.1073835353735992	[48]	[48]	9	hSpCas9	negative selection	385728
148827679	148827702	5	-	26472758	Raji	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	-0.44471433144193007	[216]	[36]	-4	hSpCas9	negative selection	385729
148826888	148826911	5	+	26472758	Raji	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.8814112237613506	[268]	[114]	7	hSpCas9	negative selection	385730
148827001	148827024	5	-	26472758	Raji	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.7730348488737279	[323]	[43]	-5	hSpCas9	negative selection	385731
148827317	148827340	5	-	26472758	Raji	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	-0.020569195593396955	[270]	[61]	0	hSpCas9	negative selection	385732
148827462	148827485	5	-	26472758	Raji	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	-0.24675918437893274	[316]	[61]	-2	hSpCas9	negative selection	385733
148827545	148827568	5	-	26472758	Raji	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	-0.4342751811266964	[360]	[61]	-4	hSpCas9	negative selection	385734
148827197	148827220	5	+	26472758	K562	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	0.6439265286516863	[466]	[615]	5	hSpCas9	negative selection	576843
148827882	148827905	5	+	26472758	K562	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	1.5464472651161043	[291]	[719]	9	hSpCas9	negative selection	576844
148827430	148827453	5	-	26472758	K562	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.000611945308826245	[652]	[550]	0	hSpCas9	negative selection	576845
148827442	148827465	5	-	26472758	K562	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	0.06258040468063353	[75]	[66]	0	hSpCas9	negative selection	576846
148827679	148827702	5	-	26472758	K562	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.5937529798944612	[437]	[557]	5	hSpCas9	negative selection	576847
148826888	148826911	5	+	26472758	K562	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.781352565259504	[620]	[900]	6	hSpCas9	negative selection	576848
148827001	148827024	5	-	26472758	K562	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	1.02530143836286	[329]	[566]	8	hSpCas9	negative selection	576849
148827317	148827340	5	-	26472758	K562	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.8405866830954836	[341]	[516]	7	hSpCas9	negative selection	576850
148827462	148827485	5	-	26472758	K562	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	-0.22773574241075767	[540]	[389]	-1	hSpCas9	negative selection	576851
148827545	148827568	5	-	26472758	K562	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	-0.3220544014878448	[658]	[444]	-2	hSpCas9	negative selection	576852
148827001	148827024	5	-	26627737	DLD1	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.7383941584397656	[762]	[185,86,151]	-6	hSpCas9	negative selection	827449
148827058	148827081	5	-	26627737	DLD1	viability	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.046385646099890376	[1200]	[439,276,433]	0	hSpCas9	negative selection	827450
148827262	148827285	5	+	26627737	DLD1	viability	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-0.08607432070846921	[309]	[88,87,95]	-1	hSpCas9	negative selection	827451
148827281	148827304	5	-	26627737	DLD1	viability	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	0.33094578143905967	[340]	[65,138,188]	3	hSpCas9	negative selection	827452
148827891	148827914	5	+	26627737	DLD1	viability	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.10985541497846585	[1339]	[221,571,551]	1	hSpCas9	negative selection	827453
148827920	148827943	5	+	26627737	DLD1	viability	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	-0.09736110695331579	[295]	[139,82,42]	-1	hSpCas9	negative selection	827454
148827001	148827024	5	-	26627737	GBM cells	viability after 5 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.00853836606018371	[341]	[169,198]	0	hSpCas9	negative selection	909764
148827058	148827081	5	-	26627737	GBM cells	viability after 5 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.050916968330735446	[359]	[215,183]	0	hSpCas9	negative selection	909765
148827262	148827285	5	+	26627737	GBM cells	viability after 5 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.08572987402588399	[216]	[120,125]	1	hSpCas9	negative selection	909766
148827281	148827304	5	-	26627737	GBM cells	viability after 5 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-0.200621798665229	[149]	[63,75]	-3	hSpCas9	negative selection	909767
148827891	148827914	5	+	26627737	GBM cells	viability after 5 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	-0.07570080669440082	[506]	[305,209]	-1	hSpCas9	negative selection	909768
148827920	148827943	5	+	26627737	GBM cells	viability after 5 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	-0.1750867065580911	[199]	[94,94]	-3	hSpCas9	negative selection	909769
148827001	148827024	5	-	26627737	GBM cells	viability after 13 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.12654566822979757	[341]	[196,147]	-1	hSpCas9	negative selection	992079
148827058	148827081	5	-	26627737	GBM cells	viability after 13 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.4041884213275372	[359]	[263,253]	5	hSpCas9	negative selection	992080
148827262	148827285	5	+	26627737	GBM cells	viability after 13 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.17957817474127097	[216]	[134,131]	2	hSpCas9	negative selection	992081
148827281	148827304	5	-	26627737	GBM cells	viability after 13 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-0.4807094459389252	[149]	[86,34]	-5	hSpCas9	negative selection	992082
148827891	148827914	5	+	26627737	GBM cells	viability after 13 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.05386819083339711	[506]	[284,285]	0	hSpCas9	negative selection	992083
148827920	148827943	5	+	26627737	GBM cells	viability after 13 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	-0.5057525637787139	[199]	[103,53]	-6	hSpCas9	negative selection	992084
148827001	148827024	5	-	26627737	GBM cells	viability after 21 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.3655262029017574	[341]	[253,225]	4	hSpCas9	negative selection	1074394
148827058	148827081	5	-	26627737	GBM cells	viability after 21 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	-0.5182755977836668	[359]	[146,126]	-5	hSpCas9	negative selection	1074395
148827262	148827285	5	+	26627737	GBM cells	viability after 21 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	1.0452086902064608	[216]	[259,227]	9	hSpCas9	negative selection	1074396
148827281	148827304	5	-	26627737	GBM cells	viability after 21 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-0.9863493073393232	[149]	[37,43]	-7	hSpCas9	negative selection	1074397
148827891	148827914	5	+	26627737	GBM cells	viability after 21 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.21606896786611607	[506]	[332,307]	2	hSpCas9	negative selection	1074398
148827920	148827943	5	+	26627737	GBM cells	viability after 21 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	-0.8032347460579228	[199]	[55,67]	-6	hSpCas9	negative selection	1074399
148827001	148827024	5	-	26627737	RPE1	viability after 9 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.2564855623585883	[891]	[316,354]	1	hSpCas9	negative selection	1156709
148827058	148827081	5	-	26627737	RPE1	viability after 9 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.8532781644196773	[515]	[338,230]	5	hSpCas9	negative selection	1156710
148827262	148827285	5	+	26627737	RPE1	viability after 9 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-0.23860543644209248	[959]	[183,345]	-2	hSpCas9	negative selection	1156711
148827281	148827304	5	-	26627737	RPE1	viability after 9 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-0.31193888182401874	[84]	[20,21]	-2	hSpCas9	negative selection	1156712
148827891	148827914	5	+	26627737	RPE1	viability after 9 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	-0.2463212411565232	[2429]	[877,335]	-2	hSpCas9	negative selection	1156713
148827920	148827943	5	+	26627737	RPE1	viability after 9 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.02450526778157941	[597]	[182,199]	0	hSpCas9	negative selection	1156714
148827001	148827024	5	-	26627737	RPE1	viability after 12 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.09327803586698549	[891]	[192,321]	0	hSpCas9	negative selection	1239024
148827058	148827081	5	-	26627737	RPE1	viability after 12 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.7246278414556879	[515]	[248,207]	4	hSpCas9	negative selection	1239025
148827262	148827285	5	+	26627737	RPE1	viability after 12 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-0.10698339474972784	[959]	[170,311]	0	hSpCas9	negative selection	1239026
148827281	148827304	5	-	26627737	RPE1	viability after 12 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-0.40415780208445184	[84]	[25,7]	-3	hSpCas9	negative selection	1239027
148827891	148827914	5	+	26627737	RPE1	viability after 12 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	-0.14535957001255007	[2429]	[769,399]	-1	hSpCas9	negative selection	1239028
148827920	148827943	5	+	26627737	RPE1	viability after 12 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.40061337403400116	[597]	[214,208]	2	hSpCas9	negative selection	1239029
148827001	148827024	5	-	26627737	RPE1	viability after 15 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.4275493897181264	[891]	[374,304]	2	hSpCas9	negative selection	1321339
148827058	148827081	5	-	26627737	RPE1	viability after 15 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	1.1006134606959392	[515]	[283,340]	6	hSpCas9	negative selection	1321340
148827262	148827285	5	+	26627737	RPE1	viability after 15 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-0.5576293338235987	[959]	[127,238]	-4	hSpCas9	negative selection	1321341
148827281	148827304	5	-	26627737	RPE1	viability after 15 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	1.3558274486517004	[84]	[2,117]	7	hSpCas9	negative selection	1321342
148827891	148827914	5	+	26627737	RPE1	viability after 15 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	-0.1360995594369241	[2429]	[877,381]	-1	hSpCas9	negative selection	1321343
148827920	148827943	5	+	26627737	RPE1	viability after 15 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	1.077856570625666	[597]	[464,252]	6	hSpCas9	negative selection	1321344
148827001	148827024	5	-	26627737	RPE1	viability after 18 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.3036859186264007	[891]	[154,448]	2	hSpCas9	negative selection	1403654
148827058	148827081	5	-	26627737	RPE1	viability after 18 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	1.2297256804860672	[515]	[255,401]	7	hSpCas9	negative selection	1403655
148827262	148827285	5	+	26627737	RPE1	viability after 18 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-0.020671873499127413	[959]	[222,289]	0	hSpCas9	negative selection	1403656
148827281	148827304	5	-	26627737	RPE1	viability after 18 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	1.182688027028696	[84]	[24,80]	6	hSpCas9	negative selection	1403657
148827891	148827914	5	+	26627737	RPE1	viability after 18 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.32423269710652947	[2429]	[996,632]	2	hSpCas9	negative selection	1403658
148827920	148827943	5	+	26627737	RPE1	viability after 18 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.3836515529988552	[597]	[240,177]	2	hSpCas9	negative selection	1403659
148827001	148827024	5	-	26627737	HeLa	viability after 8 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.45722905353777	[392]	[100,325,246]	4	hSpCas9	negative selection	1485969
148827058	148827081	5	-	26627737	HeLa	viability after 8 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	-1.720799362694766	[875]	[226,51,93]	-9	hSpCas9	negative selection	1485970
148827262	148827285	5	+	26627737	HeLa	viability after 8 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.5448260407054693	[365]	[89,362,213]	5	hSpCas9	negative selection	1485971
148827281	148827304	5	-	26627737	HeLa	viability after 8 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-1.827359466781739	[425]	[69,58,32]	-9	hSpCas9	negative selection	1485972
148827891	148827914	5	+	26627737	HeLa	viability after 8 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.4079556579509609	[737]	[370,511,385]	4	hSpCas9	negative selection	1485973
148827920	148827943	5	+	26627737	HeLa	viability after 8 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.13887492332182272	[322]	[131,242,88]	1	hSpCas9	negative selection	1485974
148827001	148827024	5	-	26627737	HeLa	viability after 12 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.4193733364163314	[392]	[134,99,131]	-4	hSpCas9	negative selection	1568284
148827058	148827081	5	-	26627737	HeLa	viability after 12 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	-0.748005217110125	[875]	[315,239,90]	-6	hSpCas9	negative selection	1568285
148827262	148827285	5	+	26627737	HeLa	viability after 12 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.23161558491379308	[365]	[140,174,215]	2	hSpCas9	negative selection	1568286
148827281	148827304	5	-	26627737	HeLa	viability after 12 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-2.861359234404017	[425]	[10,26,33]	-9	hSpCas9	negative selection	1568287
148827891	148827914	5	+	26627737	HeLa	viability after 12 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.3602318877944637	[737]	[282,488,388]	3	hSpCas9	negative selection	1568288
148827920	148827943	5	+	26627737	HeLa	viability after 12 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	-0.534866239768196	[322]	[13,149,103]	-5	hSpCas9	negative selection	1568289
148827001	148827024	5	-	26627737	HeLa	viability after 15 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.05307527642993996	[392]	[168,161,166]	0	hSpCas9	negative selection	1650599
148827058	148827081	5	-	26627737	HeLa	viability after 15 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	-0.5891468817981879	[875]	[354,197,149]	-5	hSpCas9	negative selection	1650600
148827262	148827285	5	+	26627737	HeLa	viability after 15 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.15767379112731758	[365]	[54,194,256]	1	hSpCas9	negative selection	1650601
148827281	148827304	5	-	26627737	HeLa	viability after 15 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-2.469637559247898	[425]	[28,8,57]	-9	hSpCas9	negative selection	1650602
148827891	148827914	5	+	26627737	HeLa	viability after 15 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.42356906001718486	[737]	[396,299,520]	3	hSpCas9	negative selection	1650603
148827920	148827943	5	+	26627737	HeLa	viability after 15 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	-0.6422278405105863	[322]	[65,162,18]	-5	hSpCas9	negative selection	1650604
148827001	148827024	5	-	26627737	HeLa	viability after 18 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.01822626992391939	[392]	[112,124,166]	0	hSpCas9	negative selection	1732914
148827058	148827081	5	-	26627737	HeLa	viability after 18 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	-0.619348539185049	[875]	[234,155,149]	-5	hSpCas9	negative selection	1732915
148827262	148827285	5	+	26627737	HeLa	viability after 18 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.1926111145353397	[365]	[37,169,256]	1	hSpCas9	negative selection	1732916
148827281	148827304	5	-	26627737	HeLa	viability after 18 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-2.400714473077688	[425]	[21,7,57]	-9	hSpCas9	negative selection	1732917
148827891	148827914	5	+	26627737	HeLa	viability after 18 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.4222795161978752	[737]	[265,247,520]	3	hSpCas9	negative selection	1732918
148827920	148827943	5	+	26627737	HeLa	viability after 18 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	-0.5806897396207282	[322]	[48,137,18]	-5	hSpCas9	negative selection	1732919
148827001	148827024	5	-	26627737	HCT116	viability after 6 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	1.0056790331002303	[639]	[221,190]	5	hSpCas9	negative selection	1815229
148827058	148827081	5	-	26627737	HCT116	viability after 6 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	1.299616500673003	[1150]	[311,518]	7	hSpCas9	negative selection	1815230
148827262	148827285	5	+	26627737	HCT116	viability after 6 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	1.6315685585875765	[475]	[392,142]	8	hSpCas9	negative selection	1815231
148827281	148827304	5	-	26627737	HCT116	viability after 6 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	2.2847845141049956	[104]	[131,51]	9	hSpCas9	negative selection	1815232
148827891	148827914	5	+	26627737	HCT116	viability after 6 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	1.1476141887359645	[1566]	[1150,211]	6	hSpCas9	negative selection	1815233
148827920	148827943	5	+	26627737	HCT116	viability after 6 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	-0.4920890401423353	[658]	[121,46]	-3	hSpCas9	negative selection	1815234
148827001	148827024	5	-	26627737	HCT116	viability after 8 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.34728057189098555	[477]	[256,238,126]	-4	hSpCas9	negative selection	1897544
148827058	148827081	5	-	26627737	HCT116	viability after 8 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	-0.3048906827945771	[431]	[148,209,217]	-4	hSpCas9	negative selection	1897545
148827262	148827285	5	+	26627737	HCT116	viability after 8 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-0.2913059937342588	[442]	[219,196,181]	-3	hSpCas9	negative selection	1897546
148827281	148827304	5	-	26627737	HCT116	viability after 8 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	0.7413860375213343	[96]	[85,91,89]	7	hSpCas9	negative selection	1897547
148827891	148827914	5	+	26627737	HCT116	viability after 8 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.7340574278242874	[445]	[390,343,489]	7	hSpCas9	negative selection	1897548
148827920	148827943	5	+	26627737	HCT116	viability after 8 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.747703673150773	[181]	[122,264,116]	7	hSpCas9	negative selection	1897549
148827001	148827024	5	-	26627737	HCT116	viability after 9 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.34077455618214725	[639]	[116,294]	2	hSpCas9	negative selection	1979859
148827058	148827081	5	-	26627737	HCT116	viability after 9 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.30274891105079693	[1150]	[711,115]	2	hSpCas9	negative selection	1979860
148827262	148827285	5	+	26627737	HCT116	viability after 9 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	1.1397799597201361	[475]	[288,272]	7	hSpCas9	negative selection	1979861
148827281	148827304	5	-	26627737	HCT116	viability after 9 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	1.9659467307838812	[104]	[113,105]	9	hSpCas9	negative selection	1979862
148827891	148827914	5	+	26627737	HCT116	viability after 9 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.9494761710326665	[1566]	[1193,502]	6	hSpCas9	negative selection	1979863
148827920	148827943	5	+	26627737	HCT116	viability after 9 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	-0.916496371319948	[658]	[71,109]	-6	hSpCas9	negative selection	1979864
148827001	148827024	5	-	26627737	HCT116	viability after 12 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.32398719813671295	[477]	[195,223,182]	-3	hSpCas9	negative selection	2062174
148827058	148827081	5	-	26627737	HCT116	viability after 12 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.2692051990719342	[431]	[257,348,216]	2	hSpCas9	negative selection	2062175
148827262	148827285	5	+	26627737	HCT116	viability after 12 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-1.0320908275444625	[442]	[62,113,168]	-8	hSpCas9	negative selection	2062176
148827281	148827304	5	-	26627737	HCT116	viability after 12 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	0.8341513650766919	[96]	[75,92,104]	7	hSpCas9	negative selection	2062177
148827891	148827914	5	+	26627737	HCT116	viability after 12 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.8048575193591586	[445]	[411,319,493]	7	hSpCas9	negative selection	2062178
148827920	148827943	5	+	26627737	HCT116	viability after 12 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.7430413960571158	[181]	[136,189,155]	6	hSpCas9	negative selection	2062179
148827001	148827024	5	-	26627737	HCT116	viability after 15 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.2141205044050073	[477]	[405,327,232]	2	hSpCas9	negative selection	2144489
148827058	148827081	5	-	26627737	HCT116	viability after 15 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.11292903245789931	[431]	[223,348,226]	1	hSpCas9	negative selection	2144490
148827262	148827285	5	+	26627737	HCT116	viability after 15 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-1.0982950216626761	[442]	[129,121,105]	-8	hSpCas9	negative selection	2144491
148827281	148827304	5	-	26627737	HCT116	viability after 15 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	0.5420200955155168	[96]	[76,98,66]	5	hSpCas9	negative selection	2144492
148827891	148827914	5	+	26627737	HCT116	viability after 15 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.7771807569382841	[445]	[409,351,549]	6	hSpCas9	negative selection	2144493
148827920	148827943	5	+	26627737	HCT116	viability after 15 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.3799937496247058	[181]	[98,205,98]	3	hSpCas9	negative selection	2144494
148827001	148827024	5	-	26627737	HCT116	viability after 18 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.37425281814929834	[477]	[201,115,222]	-3	hSpCas9	negative selection	2226804
148827058	148827081	5	-	26627737	HCT116	viability after 18 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.559325408749664	[431]	[224,326,372]	5	hSpCas9	negative selection	2226805
148827262	148827285	5	+	26627737	HCT116	viability after 18 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-1.1716268298335968	[442]	[68,81,136]	-8	hSpCas9	negative selection	2226806
148827281	148827304	5	-	26627737	HCT116	viability after 18 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	1.280758044919999	[96]	[209,12,125]	8	hSpCas9	negative selection	2226807
148827891	148827914	5	+	26627737	HCT116	viability after 18 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.5001655364939307	[445]	[341,228,350]	4	hSpCas9	negative selection	2226808
148827920	148827943	5	+	26627737	HCT116	viability after 18 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.6808677640203072	[181]	[201,125,93]	5	hSpCas9	negative selection	2226809
148826841	148826864	5	-	24336569	HL60	viability	AAGAAGGCGCTGCCGTTCCCGGG	ADRB2	ENSG00000169252	0.39664866757604	[564]	[1573]	3	hSpCas9	negative selection	2246832
148826846	148826869	5	+	24336569	HL60	viability	GAACGGCAGCGCCTTCTTGCTGG	ADRB2	ENSG00000169252	0.6649309064572406	[731]	[2455]	5	hSpCas9	negative selection	2246833
148826856	148826879	5	+	24336569	HL60	viability	GCCTTCTTGCTGGCACCCAATGG	ADRB2	ENSG00000169252	0.19303130403196472	[302]	[732]	1	hSpCas9	negative selection	2246834
148826870	148826893	5	+	24336569	HL60	viability	ACCCAATGGAAGCCATGCGCCGG	ADRB2	ENSG00000169252	0.477640232171234	[318]	[939]	4	hSpCas9	negative selection	2246835
148826882	148826905	5	-	24336569	HL60	viability	TGACGTCGTGGTCCGGCGCATGG	ADRB2	ENSG00000169252	0.22862801350052628	[562]	[1395]	2	hSpCas9	negative selection	2246836
148826888	148826911	5	+	24336569	HL60	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.7866704514971299	[414]	[1514]	6	hSpCas9	negative selection	2246837
148826893	148826916	5	+	24336569	HL60	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.17157902943494996	[3368]	[6329]	-1	hSpCas9	negative selection	2246838
148826900	148826923	5	+	24336569	HL60	viability	CGTCACGCAGGAAAGGGACGAGG	ADRB2	ENSG00000169252	-0.15373438711905862	[920]	[1751]	-1	hSpCas9	negative selection	2246839
148826905	148826928	5	+	24336569	HL60	viability	CGCAGGAAAGGGACGAGGTGTGG	ADRB2	ENSG00000169252	-0.09122621161866874	[518]	[1030]	-1	hSpCas9	negative selection	2246840
148826912	148826935	5	+	24336569	HL60	viability	AAGGGACGAGGTGTGGGTGGTGG	ADRB2	ENSG00000169252	1.6233210877881599	[101]	[664]	9	hSpCas9	negative selection	2246841
148826841	148826864	5	-	24336569	KBM7	viability	AAGAAGGCGCTGCCGTTCCCGGG	ADRB2	ENSG00000169252	0.06951500438757546	[485]	[1390]	0	hSpCas9	negative selection	2314009
148826846	148826869	5	+	24336569	KBM7	viability	GAACGGCAGCGCCTTCTTGCTGG	ADRB2	ENSG00000169252	0.6202275483465022	[425]	[1785]	5	hSpCas9	negative selection	2314010
148826856	148826879	5	+	24336569	KBM7	viability	GCCTTCTTGCTGGCACCCAATGG	ADRB2	ENSG00000169252	-0.005703651774821461	[232]	[632]	0	hSpCas9	negative selection	2314011
148826870	148826893	5	+	24336569	KBM7	viability	ACCCAATGGAAGCCATGCGCCGG	ADRB2	ENSG00000169252	-0.8725584449664316	[630]	[939]	-6	hSpCas9	negative selection	2314012
148826882	148826905	5	-	24336569	KBM7	viability	TGACGTCGTGGTCCGGCGCATGG	ADRB2	ENSG00000169252	-0.1456888548980652	[463]	[1143]	-1	hSpCas9	negative selection	2314013
148826888	148826911	5	+	24336569	KBM7	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	-0.5331306406640959	[494]	[932]	-4	hSpCas9	negative selection	2314014
148826893	148826916	5	+	24336569	KBM7	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.49080103039901246	[2002]	[7676]	4	hSpCas9	negative selection	2314015
148826900	148826923	5	+	24336569	KBM7	viability	CGTCACGCAGGAAAGGGACGAGG	ADRB2	ENSG00000169252	0.8590242242223105	[529]	[2621]	7	hSpCas9	negative selection	2314016
148826905	148826928	5	+	24336569	KBM7	viability	CGCAGGAAAGGGACGAGGTGTGG	ADRB2	ENSG00000169252	-0.026336547743330496	[521]	[1397]	0	hSpCas9	negative selection	2314017
148826912	148826935	5	+	24336569	KBM7	viability	AAGGGACGAGGTGTGGGTGGTGG	ADRB2	ENSG00000169252	-0.12104184840893051	[249]	[626]	-1	hSpCas9	negative selection	2314018
148826415	148826438	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTGGTGGCCCGCCCTCCAGGG	ADRB2	ENSG00000169252	-0.909961710400704	[61,23]	[6,1]	-5	dCas9-VP64	positive selection	2383059
148826459	148826482	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCCTCCTTCTCCTGGGGCTGG	ADRB2	ENSG00000169252	0.17268072897889708	[52,69]	[20,8]	0	dCas9-VP64	positive selection	2383060
148826436	148826459	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGCAGTTGGGCCCCGCCCGGG	ADRB2	ENSG00000169252	-0.731686614797157	[10,17]	[1,0]	-4	dCas9-VP64	positive selection	2383061
148826415	148826438	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTGGTGGCCCGCCCTCCAGGG	ADRB2	ENSG00000169252	-0.3640112862764213	[50,76]	[10,19]	-4	dCas9-VP64	positive selection	2478314
148826459	148826482	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCCTCCTTCTCCTGGGGCTGG	ADRB2	ENSG00000169252	-0.1984153017959988	[209,117]	[40,51]	-2	dCas9-VP64	positive selection	2478315
148826436	148826459	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGCAGTTGGGCCCCGCCCGGG	ADRB2	ENSG00000169252	-0.4076736002043152	[117,13]	[21,10]	-4	dCas9-VP64	positive selection	2478316
148827001	148827024	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.6076972939189402	[2,2]	[2,0]	-7	hSpCas9	positive selection	2969219
148826857	148826880	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTTCTTGCTGGCACCCAATGG	ADRB2	ENSG00000169252	0.19289403583626902	[2,3]	[4,2]	4	hSpCas9	positive selection	2969220
148827264	148827287	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGACCAAGAATAAGGCCCGGG	ADRB2	ENSG00000169252	0.436372543203416	[3,2]	[2,3]	8	hSpCas9	positive selection	2969221
148827442	148827465	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	-0.24660980762852894	[2,3]	[2,1]	-4	hSpCas9	positive selection	2969222
148827001	148827024	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.3511679212280412	[2,2]	[3,1]	6	hSpCas9	positive selection	3037077
148826857	148826880	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTTCTTGCTGGCACCCAATGG	ADRB2	ENSG00000169252	0.7473324370433376	[2,2]	[3,3]	9	hSpCas9	positive selection	3037078
148827264	148827287	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGACCAAGAATAAGGCCCGGG	ADRB2	ENSG00000169252	-0.22792510036484442	[3,3]	[1,1]	-3	hSpCas9	positive selection	3037079
148827442	148827465	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	0.36904395226902426	[2,2]	[1,2]	6	hSpCas9	positive selection	3037080
148827007	148827030		-	24336571	A375	resistance to PLX after 7 days	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.1427946558246591	[4,3]	[3,4]	4	hSpCas9	positive selection	3107355
148827734	148827757		-	24336571	A375	resistance to PLX after 7 days	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	-0.4280702553806724	[14,7]	[7,8]	-9	hSpCas9	positive selection	3107365
148827007	148827030		-	24336571	A375	resistance to PLX after 14 days	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.6563145183070195	[2,4]	[2,2]	6	hSpCas9	positive selection	3165148
148827734	148827757		-	24336571	A375	resistance to PLX after 14 days	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	-1.1477165190574743	[10,18]	[2,2]	-9	hSpCas9	positive selection	3165158
148827007	148827030		-	24336571	A375	viability after 7 days	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	-0.11063804050976334	[4]	[4,3]	-1	hSpCas9	negative selection	3222941
148827734	148827757		-	24336571	A375	viability after 7 days	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.20653193739305686	[10]	[14,7]	3	hSpCas9	negative selection	3222951
148827007	148827030		-	24336571	A375	viability after 14 days	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	-0.1014227330705757	[4]	[2,4]	-1	hSpCas9	negative selection	3280734
148827734	148827757		-	24336571	A375	viability after 14 days	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.5537342778461676	[10]	[10,18]	7	hSpCas9	negative selection	3280744
148827007	148827030	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	1.4876719985734543	[62,45]	[0,0]	6	hSpCas9	positive selection	3335797
148827734	148827757	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	-1.0527370371632094	[298,335]	[0,0]	-7	hSpCas9	positive selection	3335798
148826894	148826917	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	2.1690316059517074	[36,30]	[0,0]	7	hSpCas9	positive selection	3335799
148828014	148828037	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-1.2934205739374083	[374,374]	[0,0]	-8	hSpCas9	positive selection	3355046
148827136	148827159	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	-2.0418818069414435	[629,629]	[0,0]	-9	hSpCas9	positive selection	3355047
148826893	148826916	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	2.087401210003523	[35,35]	[0,0]	7	hSpCas9	positive selection	3355048
148827001	148827024	5	-	26780180	HT29	viability (Avana library 4 designs)	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	1.57712236140476	[]	[]	6	hSpCas9	negative selection	3405285
148826856	148826879	5	+	26780180	HT29	viability (Avana library 4 designs)	GCCTTCTTGCTGGCACCCAATGG	ADRB2	ENSG00000169252	-0.10773337815046	[]	[]	-2	hSpCas9	negative selection	3405286
148827263	148827286	5	+	26780180	HT29	viability (Avana library 4 designs)	GCTGACCAAGAATAAGGCCCGGG	ADRB2	ENSG00000169252	2.55218494760015	[]	[]	8	hSpCas9	negative selection	3405287
148827442	148827465	5	-	26780180	HT29	viability (Avana library 4 designs)	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	0.72118622237183	[]	[]	2	hSpCas9	negative selection	3405288
148827001	148827024	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	1.6784117776214	[]	[]	2	hSpCas9	negative selection	3477220
148827442	148827465	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	0.0931786446083808	[]	[]	0	hSpCas9	negative selection	3477221
148827263	148827286	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGACCAAGAATAAGGCCCGGG	ADRB2	ENSG00000169252	-2.31699736499845	[]	[]	-3	hSpCas9	negative selection	3477222
148826856	148826879	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTTCTTGCTGGCACCCAATGG	ADRB2	ENSG00000169252	2.64801204388564	[]	[]	4	hSpCas9	negative selection	3477223
148827436	148827459	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGAAGGACACGATGGAAGAGG	ADRB2	ENSG00000169252	0.00734480048436836	[]	[]	0	hSpCas9	negative selection	3477224
148826900	148826923	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTCACGCAGGAAAGGGACGAGG	ADRB2	ENSG00000169252	6.41075523433487	[]	[]	9	hSpCas9	negative selection	3477225
148827001	148827024	5	-	26780180	A375	viability (Avana lentiGuide)	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.232115308939179	[]	[]	0	hSpCas9	negative selection	3585879
148827442	148827465	5	-	26780180	A375	viability (Avana lentiGuide)	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	5.13325100753518	[]	[]	4	hSpCas9	negative selection	3585880
148827263	148827286	5	+	26780180	A375	viability (Avana lentiGuide)	GCTGACCAAGAATAAGGCCCGGG	ADRB2	ENSG00000169252	5.11828864435483	[]	[]	4	hSpCas9	negative selection	3585881
148826856	148826879	5	+	26780180	A375	viability (Avana lentiGuide)	GCCTTCTTGCTGGCACCCAATGG	ADRB2	ENSG00000169252	-1.6856112744233	[]	[]	-3	hSpCas9	negative selection	3585882
148827436	148827459	5	-	26780180	A375	viability (Avana lentiGuide)	GTAGAAGGACACGATGGAAGAGG	ADRB2	ENSG00000169252	6.22169332415748	[]	[]	5	hSpCas9	negative selection	3585883
148826900	148826923	5	+	26780180	A375	viability (Avana lentiGuide)	CGTCACGCAGGAAAGGGACGAGG	ADRB2	ENSG00000169252	6.9360893906435	[]	[]	5	hSpCas9	negative selection	3585884
148827001	148827024	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.11064958539714087	[4]	[5,2]	-2	hSpCas9	positive selection	3694538
148827442	148827465	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	-0.6642733202238855	[4]	[4,0]	-7	hSpCas9	positive selection	3694539
148827263	148827286	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGACCAAGAATAAGGCCCGGG	ADRB2	ENSG00000169252	-0.22548151696510405	[3]	[3,2]	-4	hSpCas9	positive selection	3694540
148826856	148826879	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTTCTTGCTGGCACCCAATGG	ADRB2	ENSG00000169252	0.05653820619812058	[4]	[5,4]	1	hSpCas9	positive selection	3694541
148827436	148827459	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGAAGGACACGATGGAAGAGG	ADRB2	ENSG00000169252	0.08811203342927894	[4]	[5,4]	2	hSpCas9	positive selection	3694542
148826900	148826923	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTCACGCAGGAAAGGGACGAGG	ADRB2	ENSG00000169252	0.4336122419261542	[4]	[5,5]	9	hSpCas9	positive selection	3694543
148827001	148827024	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.07384038778120508	[4]	[2,4]	-1	hSpCas9	positive selection	3803145
148827442	148827465	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	-0.11433504279132362	[4]	[2,4]	-2	hSpCas9	positive selection	3803146
148827263	148827286	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGACCAAGAATAAGGCCCGGG	ADRB2	ENSG00000169252	-0.6189205844750894	[4]	[1,2]	-7	hSpCas9	positive selection	3803147
148826856	148826879	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTTCTTGCTGGCACCCAATGG	ADRB2	ENSG00000169252	0.31235434571092474	[5]	[5,4]	8	hSpCas9	positive selection	3803148
148827436	148827459	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGAAGGACACGATGGAAGAGG	ADRB2	ENSG00000169252	-0.035512891353518886	[5]	[3,4]	0	hSpCas9	positive selection	3803149
148826900	148826923	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTCACGCAGGAAAGGGACGAGG	ADRB2	ENSG00000169252	-0.3813931326070011	[5]	[4,1]	-5	hSpCas9	positive selection	3803150
148826893	148826916	5	+	26780180	A375	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.797434044881334	[]	[]	3	hSpCas9	negative selection	3911610
148826894	148826917	5	-	26780180	A375	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.293074208731246	[]	[]	0	hSpCas9	negative selection	3911611
148827007	148827030	5	-	26780180	A375	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.993880959205506	[]	[]	4	hSpCas9	negative selection	3911612
148827136	148827159	5	+	26780180	A375	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.0706409866200841	[]	[]	0	hSpCas9	negative selection	3911613
148827734	148827757	5	-	26780180	A375	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.581621113897898	[]	[]	1	hSpCas9	negative selection	3911614
148828014	148828037	5	-	26780180	A375	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	0.911984411563454	[]	[]	4	hSpCas9	negative selection	3911615
148826893	148826916	5	+	26780180	HT29	viability (GeCKOv2 library)	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	1.24803433855654	[]	[]	6	hSpCas9	negative selection	4019576
148826894	148826917	5	-	26780180	HT29	viability (GeCKOv2 library)	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.0327841539021512	[]	[]	0	hSpCas9	negative selection	4019577
148827007	148827030	5	-	26780180	HT29	viability (GeCKOv2 library)	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.450277159117963	[]	[]	1	hSpCas9	negative selection	4019578
148827136	148827159	5	+	26780180	HT29	viability (GeCKOv2 library)	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.780953014488452	[]	[]	3	hSpCas9	negative selection	4019579
148827734	148827757	5	-	26780180	HT29	viability (GeCKOv2 library)	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.960351393779918	[]	[]	4	hSpCas9	negative selection	4019580
148828014	148828037	5	-	26780180	HT29	viability (GeCKOv2 library)	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	1.45748905493828	[]	[]	7	hSpCas9	negative selection	4019581
148827007	148827030	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.1004842295760921	[2]	[1,1]	2	hSpCas9	positive selection	4129611
148827734	148827757	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	-0.700578625870277	[3]	[0,1]	-9	hSpCas9	positive selection	4129621
148827007	148827030	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.9363435531694544	[1]	[1,0,3,0]	6	hSpCas9	positive selection	4193633
148827734	148827757	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	1.3698700155935448	[1]	[0,2,0,3]	9	hSpCas9	positive selection	4193643
148827007	148827030	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.04276239285400785	[2]	[2,1]	0	hSpCas9	positive selection	4254761
148827734	148827757	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.33077860617109445	[3]	[3,3]	6	hSpCas9	positive selection	4254762
148826894	148826917	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	-0.2545057637677772	[1]	[1,0]	-5	hSpCas9	positive selection	4254763
148828014	148828037	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	0.21353383697078193	[3]	[4,3]	4	hSpCas9	positive selection	4319043
148827136	148827159	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.3234297910091314	[4]	[4,3]	6	hSpCas9	positive selection	4319044
148826893	148826916	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.17613111988558483	[1]	[1,0]	-4	hSpCas9	positive selection	4319045
148826946	148826968	5	+	27760321	OCIAML3	viability	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.7580113820881909	[759,610]	[700,1162]	8	hSpCas9	negative selection	4376541
148827001	148827023	5	-	27760321	OCIAML3	viability	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	1.1484167944444952	[509,430]	[731,917]	9	hSpCas9	negative selection	4376542
148827094	148827116	5	-	27760321	OCIAML3	viability	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.38839131142659733	[424,352]	[300,520]	4	hSpCas9	negative selection	4376543
148827165	148827187	5	+	27760321	OCIAML3	viability	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4376544
148827200	148827222	5	-	27760321	OCIAML3	viability	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	0.03419386396310342	[737,619]	[476,625]	0	hSpCas9	negative selection	4376545
148826946	148826968	5	+	27760321	OCIAML2	viability	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.3857316484309232	[759,610]	[593,886]	5	hSpCas9	negative selection	4460004
148827001	148827023	5	-	27760321	OCIAML2	viability	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.26809827179435897	[509,430]	[438,479]	3	hSpCas9	negative selection	4460005
148827094	148827116	5	-	27760321	OCIAML2	viability	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.24807299907145539	[424,352]	[375,366]	3	hSpCas9	negative selection	4460006
148827165	148827187	5	+	27760321	OCIAML2	viability	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4460007
148827200	148827222	5	-	27760321	OCIAML2	viability	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	-0.8442447132650753	[737,619]	[274,343]	-7	hSpCas9	negative selection	4460008
148826946	148826968	5	+	27760321	MV411	viability	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.005321480554935087	[759,610]	[540,316]	0	hSpCas9	negative selection	4543467
148827001	148827023	5	-	27760321	MV411	viability	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.6355723694446428	[509,430]	[117,320]	-4	hSpCas9	negative selection	4543468
148827094	148827116	5	-	27760321	MV411	viability	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	-0.10654835716788336	[424,352]	[234,240]	-1	hSpCas9	negative selection	4543469
148827165	148827187	5	+	27760321	MV411	viability	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4543470
148827200	148827222	5	-	27760321	MV411	viability	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	0.9828367325600887	[737,619]	[1049,629]	7	hSpCas9	negative selection	4543471
148826946	148826968	5	+	27760321	HL60	viability	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.3117377589189496	[759,610]	[578,809]	4	hSpCas9	negative selection	4626930
148827001	148827023	5	-	27760321	HL60	viability	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.5766142576200618	[509,430]	[458,689]	7	hSpCas9	negative selection	4626931
148827094	148827116	5	-	27760321	HL60	viability	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.3512237441670789	[424,352]	[373,434]	4	hSpCas9	negative selection	4626932
148827165	148827187	5	+	27760321	HL60	viability	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4626933
148827200	148827222	5	-	27760321	HL60	viability	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	-0.3922053555204712	[737,619]	[387,455]	-4	hSpCas9	negative selection	4626934
148826946	148826968	5	+	27760321	HT1080	viability	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	-0.08136878675008774	[610,476]	[116,300]	0	hSpCas9	negative selection	4710393
148827001	148827023	5	-	27760321	HT1080	viability	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.8014077924169498	[430,336]	[279,251]	4	hSpCas9	negative selection	4710394
148827094	148827116	5	-	27760321	HT1080	viability	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.09378749072534685	[352,275]	[53,220]	0	hSpCas9	negative selection	4710395
148827165	148827187	5	+	27760321	HT1080	viability	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4710396
148827200	148827222	5	-	27760321	HT1080	viability	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	0.7828169029887203	[619,483]	[511,231]	4	hSpCas9	negative selection	4710397
148826946	148826968	5	+	27760321	HT29	viability after 7 days	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.5288344497908822	[610,476]	[1048,1017,965]	7	hSpCas9	negative selection	4793856
148827001	148827023	5	-	27760321	HT29	viability after 7 days	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.80040593156135	[430,336]	[939,789,859]	9	hSpCas9	negative selection	4793857
148827094	148827116	5	-	27760321	HT29	viability after 7 days	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.14908747465580194	[352,275]	[479,479,390]	2	hSpCas9	negative selection	4793858
148827165	148827187	5	+	27760321	HT29	viability after 7 days	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4793859
148827200	148827222	5	-	27760321	HT29	viability after 7 days	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	0.06261022830106833	[619,483]	[713,996,514]	0	hSpCas9	negative selection	4793860
148826946	148826968	5	+	27760321	HT29	viability after 25 days	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.2925424270362239	[610,476]	[680,882,719]	3	hSpCas9	negative selection	4877319
148827001	148827023	5	-	27760321	HT29	viability after 25 days	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.43192485928217095	[430,336]	[474,764,536]	5	hSpCas9	negative selection	4877320
148827094	148827116	5	-	27760321	HT29	viability after 25 days	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.37395436217136535	[352,275]	[497,419,477]	4	hSpCas9	negative selection	4877321
148827165	148827187	5	+	27760321	HT29	viability after 25 days	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4877322
148827200	148827222	5	-	27760321	HT29	viability after 25 days	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	0.09028563091708808	[619,483]	[617,719,679]	0	hSpCas9	negative selection	4877323
148826946	148826968	5	+	27760321	HT29	viability after 22 days	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.21483336578397316	[610,476]	[704,890,592]	2	hSpCas9	negative selection	4960782
148827001	148827023	5	-	27760321	HT29	viability after 22 days	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.33887488458125303	[430,336]	[610,532,538]	3	hSpCas9	negative selection	4960783
148827094	148827116	5	-	27760321	HT29	viability after 22 days	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.32107833491191895	[352,275]	[438,590,331]	3	hSpCas9	negative selection	4960784
148827165	148827187	5	+	27760321	HT29	viability after 22 days	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4960785
148827200	148827222	5	-	27760321	HT29	viability after 22 days	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	0.2472129999099426	[619,483]	[632,739,903]	2	hSpCas9	negative selection	4960786
148826946	148826968	5	+	27760321	HT29	viability after 19 days	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.23469892908569134	[610,476]	[698,806,687]	2	hSpCas9	negative selection	5044245
148827001	148827023	5	-	27760321	HT29	viability after 19 days	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.20070441355739985	[430,336]	[431,350,368]	-2	hSpCas9	negative selection	5044246
148827094	148827116	5	-	27760321	HT29	viability after 19 days	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.5779619971610784	[352,275]	[601,521,494]	6	hSpCas9	negative selection	5044247
148827165	148827187	5	+	27760321	HT29	viability after 19 days	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5044248
148827200	148827222	5	-	27760321	HT29	viability after 19 days	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	-0.35113341185805746	[619,483]	[404,546,521]	-3	hSpCas9	negative selection	5044249
148826946	148826968	5	+	27760321	HT29	viability after 16 days	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.1984143155701822	[610,476]	[594,707,781]	2	hSpCas9	negative selection	5127708
148827001	148827023	5	-	27760321	HT29	viability after 16 days	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.21107680074523402	[430,336]	[564,397,537]	2	hSpCas9	negative selection	5127709
148827094	148827116	5	-	27760321	HT29	viability after 16 days	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	-0.14696196763281982	[352,275]	[525,205,243]	-1	hSpCas9	negative selection	5127710
148827165	148827187	5	+	27760321	HT29	viability after 16 days	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5127711
148827200	148827222	5	-	27760321	HT29	viability after 16 days	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	0.20635537753528022	[619,483]	[562,881,673]	2	hSpCas9	negative selection	5127712
148826946	148826968	5	+	27760321	HT29	viability after 13 days	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.26456173417337436	[610,476]	[683,824,764]	3	hSpCas9	negative selection	5211171
148827001	148827023	5	-	27760321	HT29	viability after 13 days	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.028274771759059097	[430,336]	[261,441,596]	0	hSpCas9	negative selection	5211172
148827094	148827116	5	-	27760321	HT29	viability after 13 days	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.19866215196175013	[352,275]	[424,391,437]	2	hSpCas9	negative selection	5211173
148827165	148827187	5	+	27760321	HT29	viability after 13 days	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5211174
148827200	148827222	5	-	27760321	HT29	viability after 13 days	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	-0.01963232610790866	[619,483]	[655,623,615]	0	hSpCas9	negative selection	5211175
148826946	148826968	5	+	27760321	HT29	viability after 10 days	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.570314061490962	[610,476]	[1066,1012,946]	7	hSpCas9	negative selection	5294634
148827001	148827023	5	-	27760321	HT29	viability after 10 days	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.19428946545319573	[430,336]	[380,647,617]	2	hSpCas9	negative selection	5294635
148827094	148827116	5	-	27760321	HT29	viability after 10 days	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	0.15341242075782208	[352,275]	[529,409,370]	2	hSpCas9	negative selection	5294636
148827165	148827187	5	+	27760321	HT29	viability after 10 days	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5294637
148827200	148827222	5	-	27760321	HT29	viability after 10 days	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	-0.23990691158890276	[619,483]	[375,700,674]	-3	hSpCas9	negative selection	5294638
148826946	148826968	5	+	27760321	MOLM13	viability	GTCATGTCTCTCATCGTCCTGG	ADRB2	ENSG00000169252	0.33355395607515936	[759,610]	[388,565]	2	hSpCas9	negative selection	5378097
148827001	148827023	5	-	27760321	MOLM13	viability	AGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.8014961263142228	[509,430]	[487,437]	5	hSpCas9	negative selection	5378098
148827094	148827116	5	-	27760321	MOLM13	viability	AGAATATGGGCGGCCCCAAAGG	ADRB2	ENSG00000169252	2.2578589563517903	[424,352]	[1701,485]	9	hSpCas9	negative selection	5378099
148827165	148827187	5	+	27760321	MOLM13	viability	ATTGATGTGCTGTGCGTCACGG	ADRB2	ENSG00000169252	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5378100
148827200	148827222	5	-	27760321	MOLM13	viability	ATCCACTGCGATCACGCACAGG	ADRB2	ENSG00000169252	1.2823832926965513	[737,619]	[1267,638]	8	hSpCas9	negative selection	5378101
148826602	148826625	5	+	27661255	K562	viability	GGGCAGAACGCACTGCGAAGCGG	ADRB2	ENSG00000169252	-0.07567155545551785	[1137,1162]	[922,827]	-3	dCas9-KRAB	negative selection	5461194
148826623	148826646	5	+	27661255	K562	viability	GGCTTCTTCAGAGCACGGGCTGG	ADRB2	ENSG00000169252	0.045913561956444804	[327,285]	[276,233]	1	dCas9-KRAB	negative selection	5461195
148826829	148826852	5	+	27661255	K562	viability	GCCATGGGGCAACCCGGGAACGG	ADRB2	ENSG00000169252	0.15481294693674974	[774,817]	[651,754]	5	dCas9-KRAB	negative selection	5461196
148827057	148827080	5	+	27661255	K562	viability	GCCTGTGCTGATCTGGTCATGGG	ADRB2	ENSG00000169252	0.2688175331187075	[210,204]	[236,168]	8	dCas9-KRAB	negative selection	5461197
148827007	148827030	5	-	27260156	BXPC3	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.3007918023757546	[310]	[307,373,443,497]	6	hSpCas9	negative selection	5527221
148827734	148827757	5	-	27260156	BXPC3	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.12614745412056705	[900]	[786,937,1337,1086]	2	hSpCas9	negative selection	5527222
148826894	148826917	5	-	27260156	BXPC3	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.8940927768574126	[151]	[365,249,242,316]	9	hSpCas9	negative selection	5527223
148828014	148828037	5	-	27260156	BXPC3	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	0.022182978432840228	[975]	[882,922,1064,1326]	0	hSpCas9	negative selection	5591503
148827136	148827159	5	+	27260156	BXPC3	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	-0.003443452444024775	[1213]	[1248,1119,1201,1526]	0	hSpCas9	negative selection	5591504
148826893	148826916	5	+	27260156	BXPC3	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.27117059858136994	[97]	[85,80,96,73]	-6	hSpCas9	negative selection	5591505
148827007	148827030	5	-	27260156	A673	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.07844698122951843	[310]	[463,301,448,369]	1	hSpCas9	negative selection	5648472
148827734	148827757	5	-	27260156	A673	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.04880218576850315	[900]	[1145,967,1085,1290]	1	hSpCas9	negative selection	5648473
148826894	148826917	5	-	27260156	A673	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.14043535660249518	[151]	[226,206,162,210]	3	hSpCas9	negative selection	5648474
148828014	148828037	5	-	27260156	A673	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	0.09761341008837254	[975]	[1156,1184,1340,1323]	2	hSpCas9	negative selection	5712754
148827136	148827159	5	+	27260156	A673	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.053367147388562186	[1213]	[1625,1396,1489,1552]	1	hSpCas9	negative selection	5712755
148826893	148826916	5	+	27260156	A673	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.1600842348355238	[97]	[118,163,131,106]	4	hSpCas9	negative selection	5712756
148827007	148827030	5	-	27260156	A375	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.25840868972315456	[310]	[298,485,453,495]	4	hSpCas9	negative selection	5769723
148827734	148827757	5	-	27260156	A375	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	-0.002337073930043343	[900]	[1033,959,1216,982]	0	hSpCas9	negative selection	5769724
148826894	148826917	5	-	27260156	A375	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.5348402411574738	[151]	[287,345,163,243]	7	hSpCas9	negative selection	5769725
148828014	148828037	5	-	27260156	A375	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	0.15923969306331442	[975]	[1165,1052,1520,1310]	2	hSpCas9	negative selection	5834005
148827136	148827159	5	+	27260156	A375	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.3993674172506836	[1213]	[2078,1891,1997,1547]	6	hSpCas9	negative selection	5834006
148826893	148826916	5	+	27260156	A375	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.269332865005107	[97]	[82,93,39,154]	-4	hSpCas9	negative selection	5834007
148827007	148827030	5	-	27260156	COLO741	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.39603839304771576	[310]	[471,438,642]	7	hSpCas9	negative selection	5890974
148827734	148827757	5	-	27260156	COLO741	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.024541630428943084	[900]	[1122,1249,1135]	0	hSpCas9	negative selection	5890975
148826894	148826917	5	-	27260156	COLO741	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.46652045542046494	[151]	[201,314,280]	8	hSpCas9	negative selection	5890976
148828014	148828037	5	-	27260156	COLO741	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.10668079484813764	[975]	[1249,1245,995]	-2	hSpCas9	negative selection	5955256
148827136	148827159	5	+	27260156	COLO741	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.018921498582394003	[1213]	[1724,1719,1299]	0	hSpCas9	negative selection	5955257
148826893	148826916	5	+	27260156	COLO741	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.19284617925616487	[97]	[94,105,124]	-4	hSpCas9	negative selection	5955258
148827007	148827030	5	-	27260156	CAL120	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	-0.03287489085620243	[310]	[412,352,373]	0	hSpCas9	negative selection	6012225
148827734	148827757	5	-	27260156	CAL120	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.37110674239234365	[900]	[1188,1649,1470]	5	hSpCas9	negative selection	6012226
148826894	148826917	5	-	27260156	CAL120	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.566590164045816	[151]	[101,348,360]	8	hSpCas9	negative selection	6012227
148828014	148828037	5	-	27260156	CAL120	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.22904357730898572	[975]	[1371,706,1078]	-3	hSpCas9	negative selection	6076507
148827136	148827159	5	+	27260156	CAL120	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.2523986708049144	[1213]	[2386,1457,1643]	4	hSpCas9	negative selection	6076508
148826893	148826916	5	+	27260156	CAL120	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.37963385272734174	[97]	[160,141,172]	6	hSpCas9	negative selection	6076509
148827007	148827030	5	-	27260156	CADOES1	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.3719046179301695	[310]	[296,377,381,442]	6	hSpCas9	negative selection	6133476
148827734	148827757	5	-	27260156	CADOES1	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.27123428710928577	[900]	[817,942,1082,1208]	4	hSpCas9	negative selection	6133477
148826894	148826917	5	-	27260156	CADOES1	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.8458750485458444	[151]	[196,344,212,261]	9	hSpCas9	negative selection	6133478
148828014	148828037	5	-	27260156	CADOES1	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.040124368255330944	[975]	[699,1059,944,824]	0	hSpCas9	negative selection	6197758
148827136	148827159	5	+	27260156	CADOES1	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.3064632890950778	[1213]	[1197,1730,1400,1250]	5	hSpCas9	negative selection	6197759
148826893	148826916	5	+	27260156	CADOES1	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.7691252356365692	[97]	[233,159,75,150]	9	hSpCas9	negative selection	6197760
148827007	148827030	5	-	27260156	EWS502	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.5935540137159853	[310]	[547,367,467,608]	8	hSpCas9	negative selection	6254727
148827734	148827757	5	-	27260156	EWS502	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.1948197671226678	[900]	[888,709,1464,1365]	3	hSpCas9	negative selection	6254728
148826894	148826917	5	-	27260156	EWS502	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.6385178155045551	[151]	[243,316,182,254]	9	hSpCas9	negative selection	6254729
148828014	148828037	5	-	27260156	EWS502	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.2021763330951648	[975]	[1055,882,893,726]	-4	hSpCas9	negative selection	6319009
148827136	148827159	5	+	27260156	EWS502	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.13504556560767544	[1213]	[1354,1380,1295,1632]	2	hSpCas9	negative selection	6319010
148826893	148826916	5	+	27260156	EWS502	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.4791133170473456	[97]	[121,89,38,36]	-7	hSpCas9	negative selection	6319011
148827007	148827030	5	-	27260156	EW8	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.35049248423894797	[310]	[408,332,197,374]	6	hSpCas9	negative selection	6375978
148827734	148827757	5	-	27260156	EW8	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.12953483183639813	[900]	[972,1068,669,523]	2	hSpCas9	negative selection	6375979
148826894	148826917	5	-	27260156	EW8	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.6486016373164205	[151]	[201,185,191,192]	9	hSpCas9	negative selection	6375980
148828014	148828037	5	-	27260156	EW8	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.2216741809721281	[975]	[615,794,576,733]	-4	hSpCas9	negative selection	6440260
148827136	148827159	5	+	27260156	EW8	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.12619772733244994	[1213]	[1342,1201,919,883]	2	hSpCas9	negative selection	6440261
148826893	148826916	5	+	27260156	EW8	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.3743346687245128	[97]	[91,113,116,84]	6	hSpCas9	negative selection	6440262
148827007	148827030	5	-	27260156	CORL105	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.3508737479558389	[310]	[410,437,404,591]	6	hSpCas9	negative selection	6497229
148827734	148827757	5	-	27260156	CORL105	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.10592081254237151	[900]	[1085,1095,1160,1199]	2	hSpCas9	negative selection	6497230
148826894	148826917	5	-	27260156	CORL105	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.32767703852833363	[151]	[119,202,269,303]	6	hSpCas9	negative selection	6497231
148828014	148828037	5	-	27260156	CORL105	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.23619414559284568	[975]	[858,785,1223,1049]	-4	hSpCas9	negative selection	6561511
148827136	148827159	5	+	27260156	CORL105	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	-0.06727486700785579	[1213]	[1148,1379,1493,1415]	-1	hSpCas9	negative selection	6561512
148826893	148826916	5	+	27260156	CORL105	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.03380517228687374	[97]	[85,118,182,90]	0	hSpCas9	negative selection	6561513
148827007	148827030	5	-	27260156	HS294T	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.453929540400593	[310]	[125,172,136,237]	6	hSpCas9	negative selection	6618480
148827734	148827757	5	-	27260156	HS294T	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.1342674315998046	[900]	[452,362,292,418]	1	hSpCas9	negative selection	6618481
148826894	148826917	5	-	27260156	HS294T	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.8418009207045195	[151]	[64,110,111,142]	9	hSpCas9	negative selection	6618482
148828014	148828037	5	-	27260156	HS294T	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.23373324763061887	[975]	[214,387,289,412]	-3	hSpCas9	negative selection	6682762
148827136	148827159	5	+	27260156	HS294T	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.21997880759252175	[1213]	[569,462,453,728]	3	hSpCas9	negative selection	6682763
148826893	148826916	5	+	27260156	HS294T	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.5592193597586199	[97]	[26,93,55,45]	7	hSpCas9	negative selection	6682764
148827007	148827030	5	-	27260156	HCC44	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.3123661591669033	[310]	[526,288,671,328]	5	hSpCas9	negative selection	6739731
148827734	148827757	5	-	27260156	HCC44	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.20667148691074388	[900]	[1228,921,1728,957]	3	hSpCas9	negative selection	6739732
148826894	148826917	5	-	27260156	HCC44	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.8608272005519867	[151]	[438,160,283,387]	9	hSpCas9	negative selection	6739733
148828014	148828037	5	-	27260156	HCC44	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.24010665255471608	[975]	[1137,887,1147,628]	-4	hSpCas9	negative selection	6804013
148827136	148827159	5	+	27260156	HCC44	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.20176121657141532	[1213]	[1452,1244,2025,1688]	3	hSpCas9	negative selection	6804014
148826893	148826916	5	+	27260156	HCC44	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.308077900234049	[97]	[95,51,133,88]	-5	hSpCas9	negative selection	6804015
148827007	148827030	5	-	27260156	G402	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.05002366151900217	[310]	[480,550,317,248]	0	hSpCas9	negative selection	6860982
148827734	148827757	5	-	27260156	G402	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	-0.00787655380650698	[900]	[1421,1042,856,1091]	0	hSpCas9	negative selection	6860983
148826894	148826917	5	-	27260156	G402	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.6552616186023393	[151]	[330,201,434,203]	7	hSpCas9	negative selection	6860984
148828014	148828037	5	-	27260156	G402	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.14508759816063876	[975]	[1480,909,1215,760]	-2	hSpCas9	negative selection	6925264
148827136	148827159	5	+	27260156	G402	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.46612201357889593	[1213]	[2044,1827,2216,2072]	6	hSpCas9	negative selection	6925265
148826893	148826916	5	+	27260156	G402	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.006804268632847776	[97]	[158,87,34,197]	0	hSpCas9	negative selection	6925266
148827007	148827030	5	-	27260156	L33	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.20674919049368562	[310]	[366,163,241,283]	4	hSpCas9	negative selection	6982233
148827734	148827757	5	-	27260156	L33	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.14225411847519964	[900]	[1044,420,457,1171]	3	hSpCas9	negative selection	6982234
148826894	148826917	5	-	27260156	L33	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.0773518549827692	[151]	[151,47,76,248]	1	hSpCas9	negative selection	6982235
148828014	148828037	5	-	27260156	L33	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.42840495041055715	[975]	[684,275,425,863]	-7	hSpCas9	negative selection	7046515
148827136	148827159	5	+	27260156	L33	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	-0.2555953285570436	[1213]	[964,387,638,1138]	-5	hSpCas9	negative selection	7046516
148826893	148826916	5	+	27260156	L33	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.026604057574383777	[97]	[100,30,58,113]	0	hSpCas9	negative selection	7046517
148827007	148827030	5	-	27260156	K562	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.536569397246059	[310]	[361,237,474,500]	6	hSpCas9	negative selection	7103484
148827734	148827757	5	-	27260156	K562	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.04920972962800507	[900]	[856,677,736,1006]	0	hSpCas9	negative selection	7103485
148826894	148826917	5	-	27260156	K562	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.6295551421945782	[151]	[147,211,240,225]	7	hSpCas9	negative selection	7103486
148828014	148828037	5	-	27260156	K562	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.17091766018550958	[975]	[808,1045,637,616]	-2	hSpCas9	negative selection	7167766
148827136	148827159	5	+	27260156	K562	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.5000823421165133	[1213]	[1052,2562,1867,715]	6	hSpCas9	negative selection	7167767
148826893	148826916	5	+	27260156	K562	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.7568758800250408	[97]	[56,57,82,12]	-7	hSpCas9	negative selection	7167768
148827007	148827030	5	-	27260156	HT29	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.21114393641403828	[310]	[423,379,621,328]	4	hSpCas9	negative selection	7224735
148827734	148827757	5	-	27260156	HT29	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.09830851638329208	[900]	[1360,1094,1165,1078]	2	hSpCas9	negative selection	7224736
148826894	148826917	5	-	27260156	HT29	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.41603634286595814	[151]	[241,232,217,284]	7	hSpCas9	negative selection	7224737
148828014	148828037	5	-	27260156	HT29	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.04204269693089224	[975]	[1024,1081,1323,1153]	-1	hSpCas9	negative selection	7289017
148827136	148827159	5	+	27260156	HT29	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.11516551979110434	[1213]	[1899,1757,1415,1372]	2	hSpCas9	negative selection	7289018
148826893	148826916	5	+	27260156	HT29	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.2697859794666684	[97]	[125,162,214,77]	5	hSpCas9	negative selection	7289019
148827007	148827030	5	-	27260156	MHHES1	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.5499163457434305	[310]	[463,499,538,525]	8	hSpCas9	negative selection	7345986
148827734	148827757	5	-	27260156	MHHES1	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.31195263914889415	[900]	[1475,1436,1191,1007]	5	hSpCas9	negative selection	7345987
148826894	148826917	5	-	27260156	MHHES1	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.6155648925927593	[151]	[348,237,278,199]	9	hSpCas9	negative selection	7345988
148828014	148828037	5	-	27260156	MHHES1	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.09667976492772978	[975]	[1235,894,919,1043]	-2	hSpCas9	negative selection	7410268
148827136	148827159	5	+	27260156	MHHES1	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.09460321555584494	[1213]	[2016,1696,1354,948]	1	hSpCas9	negative selection	7410269
148826893	148826916	5	+	27260156	MHHES1	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.5621811062860413	[97]	[189,148,163,149]	8	hSpCas9	negative selection	7410270
148827007	148827030	5	-	27260156	MEWO	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.2244298971490285	[310]	[257,308,436]	5	hSpCas9	negative selection	7467237
148827734	148827757	5	-	27260156	MEWO	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	-0.07226617747693431	[900]	[849,891,671]	-1	hSpCas9	negative selection	7467238
148826894	148826917	5	-	27260156	MEWO	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.7849831792690856	[151]	[213,249,264]	9	hSpCas9	negative selection	7467239
148828014	148828037	5	-	27260156	MEWO	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.0870501813448612	[975]	[864,812,901]	-2	hSpCas9	negative selection	7531519
148827136	148827159	5	+	27260156	MEWO	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	-0.024496948506563365	[1213]	[1102,1127,1115]	0	hSpCas9	negative selection	7531520
148826893	148826916	5	+	27260156	MEWO	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.3375103216870228	[97]	[86,102,151]	7	hSpCas9	negative selection	7531521
148827007	148827030	5	-	27260156	LNCAPCLONEFGC	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.18084133235466643	[310]	[304,281,474,240]	3	hSpCas9	negative selection	7588488
148827734	148827757	5	-	27260156	LNCAPCLONEFGC	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	-0.08819089954936798	[900]	[828,661,690,882]	-1	hSpCas9	negative selection	7588489
148826894	148826917	5	-	27260156	LNCAPCLONEFGC	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.9560784487604104	[151]	[281,175,468,176]	9	hSpCas9	negative selection	7588490
148828014	148828037	5	-	27260156	LNCAPCLONEFGC	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.28734839633699905	[975]	[869,728,601,674]	-4	hSpCas9	negative selection	7652770
148827136	148827159	5	+	27260156	LNCAPCLONEFGC	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.3688650053247715	[1213]	[1125,1369,1497,1705]	6	hSpCas9	negative selection	7652771
148826893	148826916	5	+	27260156	LNCAPCLONEFGC	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.31601539031534065	[97]	[78,184,132,43]	5	hSpCas9	negative selection	7652772
148827007	148827030	5	-	27260156	PANC0327	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	-0.128326113977266	[310]	[265,173,196,384]	-2	hSpCas9	negative selection	7709739
148827734	148827757	5	-	27260156	PANC0327	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.3778491265947169	[900]	[1047,1096,1030,976]	5	hSpCas9	negative selection	7709740
148826894	148826917	5	-	27260156	PANC0327	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	1.0142255076970206	[151]	[341,99,401,274]	9	hSpCas9	negative selection	7709741
148828014	148828037	5	-	27260156	PANC0327	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.15123314633502938	[975]	[1131,687,565,776]	-2	hSpCas9	negative selection	7774021
148827136	148827159	5	+	27260156	PANC0327	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.06317733329818154	[1213]	[1287,875,1177,1209]	0	hSpCas9	negative selection	7774022
148826893	148826916	5	+	27260156	PANC0327	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.08661836792886968	[97]	[27,226,31,59]	1	hSpCas9	negative selection	7774023
148827007	148827030	5	-	27260156	NCIH2009	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.22728845936106234	[310]	[575,586,373]	3	hSpCas9	negative selection	7830990
148827734	148827757	5	-	27260156	NCIH2009	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.07079045296442954	[900]	[1225,1442,1273]	1	hSpCas9	negative selection	7830991
148826894	148826917	5	-	27260156	NCIH2009	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	-0.38270944594234146	[151]	[131,177,171]	-5	hSpCas9	negative selection	7830992
148828014	148828037	5	-	27260156	NCIH2009	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.5535011861578714	[975]	[1312,745,805]	-6	hSpCas9	negative selection	7895272
148827136	148827159	5	+	27260156	NCIH2009	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.07111951471768019	[1213]	[2187,1661,1574]	1	hSpCas9	negative selection	7895273
148826893	148826916	5	+	27260156	NCIH2009	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.34707711519719475	[97]	[217,110,202]	5	hSpCas9	negative selection	7895274
148827007	148827030	5	-	27260156	NCIH1373	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	-0.04291110411947474	[310]	[303,309,335,105]	0	hSpCas9	negative selection	7952241
148827734	148827757	5	-	27260156	NCIH1373	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.38730288114828204	[900]	[2139,1289,579,372]	4	hSpCas9	negative selection	7952242
148826894	148826917	5	-	27260156	NCIH1373	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	-0.771119269636328	[151]	[111,57,89,38]	-7	hSpCas9	negative selection	7952243
148828014	148828037	5	-	27260156	NCIH1373	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.4413573065305747	[975]	[940,748,791,199]	-4	hSpCas9	negative selection	8016523
148827136	148827159	5	+	27260156	NCIH1373	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.6397596980983329	[1213]	[1751,1829,1723,843]	6	hSpCas9	negative selection	8016524
148826893	148826916	5	+	27260156	NCIH1373	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.3239527700746099	[97]	[117,36,258,36]	3	hSpCas9	negative selection	8016525
148827007	148827030	5	-	27260156	PATU8902	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.07566759509306509	[310]	[65,710,432,646]	0	hSpCas9	negative selection	8073492
148827734	148827757	5	-	27260156	PATU8902	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.2194707920824338	[900]	[1778,1487,929,1810]	2	hSpCas9	negative selection	8073493
148826894	148826917	5	-	27260156	PATU8902	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.9891806422750881	[151]	[178,849,286,397]	9	hSpCas9	negative selection	8073494
148828014	148828037	5	-	27260156	PATU8902	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.48980608100666745	[975]	[1188,725,994,939]	-5	hSpCas9	negative selection	8137774
148827136	148827159	5	+	27260156	PATU8902	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.0510462237810132	[1213]	[1958,1906,1541,1620]	0	hSpCas9	negative selection	8137775
148826893	148826916	5	+	27260156	PATU8902	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	1.2497022014369805	[97]	[278,316,289,431]	9	hSpCas9	negative selection	8137776
148827007	148827030	5	-	27260156	PANC1	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.3047079563355028	[310]	[415,363,199,336]	5	hSpCas9	negative selection	8194743
148827734	148827757	5	-	27260156	PANC1	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.3218803847432298	[900]	[930,1163,810,983]	5	hSpCas9	negative selection	8194744
148826894	148826917	5	-	27260156	PANC1	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.320646422398172	[151]	[181,171,188,115]	5	hSpCas9	negative selection	8194745
148828014	148828037	5	-	27260156	PANC1	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	0.04118263878230066	[975]	[728,1105,908,761]	0	hSpCas9	negative selection	8259025
148827136	148827159	5	+	27260156	PANC1	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	-0.011340405205036541	[1213]	[940,1255,1249,767]	0	hSpCas9	negative selection	8259026
148826893	148826916	5	+	27260156	PANC1	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.4859120704541917	[97]	[63,92,62,30]	-6	hSpCas9	negative selection	8259027
148827007	148827030	5	-	27260156	PANC0813	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.30114586334525245	[310]	[337,848,276,330]	5	hSpCas9	negative selection	8315994
148827734	148827757	5	-	27260156	PANC0813	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.002782490286371675	[900]	[1355,1048,870,993]	0	hSpCas9	negative selection	8315995
148826894	148826917	5	-	27260156	PANC0813	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	-0.39487794701096357	[151]	[144,135,113,147]	-6	hSpCas9	negative selection	8315996
148828014	148828037	5	-	27260156	PANC0813	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.5639912247827279	[975]	[727,855,752,759]	-7	hSpCas9	negative selection	8380276
148827136	148827159	5	+	27260156	PANC0813	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.02637789544277469	[1213]	[1660,1364,1231,1560]	0	hSpCas9	negative selection	8380277
148826893	148826916	5	+	27260156	PANC0813	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.11976498610963393	[97]	[107,135,102,149]	2	hSpCas9	negative selection	8380278
148827007	148827030	5	-	27260156	RDES	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.6527992804103225	[310]	[484,439,685,670]	9	hSpCas9	negative selection	8437245
148827734	148827757	5	-	27260156	RDES	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.22012809836079994	[900]	[1009,1006,1351,1540]	3	hSpCas9	negative selection	8437246
148826894	148826917	5	-	27260156	RDES	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.8268716953971579	[151]	[294,236,394,317]	9	hSpCas9	negative selection	8437247
148828014	148828037	5	-	27260156	RDES	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.19994344641201223	[975]	[746,961,1001,1264]	-3	hSpCas9	negative selection	8501527
148827136	148827159	5	+	27260156	RDES	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.4486109473794475	[1213]	[1624,1973,2017,2018]	7	hSpCas9	negative selection	8501528
148826893	148826916	5	+	27260156	RDES	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.18811749684045953	[97]	[94,144,96,185]	3	hSpCas9	negative selection	8501529
148827007	148827030	5	-	27260156	PC3	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.2622255498567497	[310]	[285,328,665,314]	6	hSpCas9	negative selection	8558496
148827734	148827757	5	-	27260156	PC3	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.142694882211842	[900]	[497,1111,1820,986]	3	hSpCas9	negative selection	8558497
148826894	148826917	5	-	27260156	PC3	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.810304704174977	[151]	[310,166,335,213]	9	hSpCas9	negative selection	8558498
148828014	148828037	5	-	27260156	PC3	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.40538816570419045	[975]	[509,704,1178,738]	-7	hSpCas9	negative selection	8622778
148827136	148827159	5	+	27260156	PC3	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.07772441099563587	[1213]	[773,1384,2062,1284]	1	hSpCas9	negative selection	8622779
148826893	148826916	5	+	27260156	PC3	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.11637728859647689	[97]	[62,160,145,72]	2	hSpCas9	negative selection	8622780
148827007	148827030	5	-	27260156	PATU8988T	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.01040023801453449	[310]	[268,386,193,375]	0	hSpCas9	negative selection	8679747
148827734	148827757	5	-	27260156	PATU8988T	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.13097736880929445	[900]	[802,1083,809,1145]	2	hSpCas9	negative selection	8679748
148826894	148826917	5	-	27260156	PATU8988T	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.8704110710228893	[151]	[114,417,195,367]	9	hSpCas9	negative selection	8679749
148828014	148828037	5	-	27260156	PATU8988T	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	0.14334473009928717	[975]	[1132,1110,790,1149]	2	hSpCas9	negative selection	8744029
148827136	148827159	5	+	27260156	PATU8988T	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.0566373769223385	[1213]	[1228,1235,1282,1124]	1	hSpCas9	negative selection	8744030
148826893	148826916	5	+	27260156	PATU8988T	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.01977173415776967	[97]	[23,112,61,194]	0	hSpCas9	negative selection	8744031
148827007	148827030	5	-	27260156	T47D	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.1779137520789117	[310]	[397,422,450,363]	4	hSpCas9	negative selection	8800998
148827734	148827757	5	-	27260156	T47D	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.14427814393271132	[900]	[1138,1199,1047,1253]	3	hSpCas9	negative selection	8800999
148826894	148826917	5	-	27260156	T47D	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.4677984189328226	[151]	[242,246,250,237]	8	hSpCas9	negative selection	8801000
148828014	148828037	5	-	27260156	T47D	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.21236310144366766	[975]	[1120,887,934,990]	-5	hSpCas9	negative selection	8865280
148827136	148827159	5	+	27260156	T47D	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.009048238200602743	[1213]	[1526,1285,1324,1572]	0	hSpCas9	negative selection	8865281
148826893	148826916	5	+	27260156	T47D	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.390097533062157	[97]	[120,103,186,190]	8	hSpCas9	negative selection	8865282
148827007	148827030	5	-	27260156	SU8686	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.24474967776510942	[310]	[332,361,420,344]	4	hSpCas9	negative selection	8922249
148827734	148827757	5	-	27260156	SU8686	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.19992973282780413	[900]	[823,1082,1093,1129]	3	hSpCas9	negative selection	8922250
148826894	148826917	5	-	27260156	SU8686	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.11442764545537076	[151]	[180,83,180,223]	2	hSpCas9	negative selection	8922251
148828014	148828037	5	-	27260156	SU8686	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.2441319062703895	[975]	[667,861,755,1017]	-4	hSpCas9	negative selection	8986531
148827136	148827159	5	+	27260156	SU8686	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	-0.007834857920800742	[1213]	[1100,969,1394,1390]	0	hSpCas9	negative selection	8986532
148826893	148826916	5	+	27260156	SU8686	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.627189716999653	[97]	[96,164,188,153]	9	hSpCas9	negative selection	8986533
148827007	148827030	5	-	27260156	SKES1	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.48299845598013275	[310]	[452,343,480,441]	8	hSpCas9	negative selection	9043500
148827734	148827757	5	-	27260156	SKES1	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.23755029041232245	[900]	[1322,1014,872,1050]	5	hSpCas9	negative selection	9043501
148826894	148826917	5	-	27260156	SKES1	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.4500098389451057	[151]	[254,215,190,175]	8	hSpCas9	negative selection	9043502
148828014	148828037	5	-	27260156	SKES1	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.2391933584170357	[975]	[619,1064,847,764]	-5	hSpCas9	negative selection	9107782
148827136	148827159	5	+	27260156	SKES1	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	-0.09655319234767279	[1213]	[1329,1210,1149,892]	-2	hSpCas9	negative selection	9107783
148826893	148826916	5	+	27260156	SKES1	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.2085711882842336	[97]	[89,198,112,61]	4	hSpCas9	negative selection	9107784
148827007	148827030	5	-	27260156	TOV112D	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.4938249408477401	[310]	[458,585,244,499]	8	hSpCas9	negative selection	9164751
148827734	148827757	5	-	27260156	TOV112D	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.35911445574349543	[900]	[1127,1425,744,1385]	6	hSpCas9	negative selection	9164752
148826894	148826917	5	-	27260156	TOV112D	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.8558827154167273	[151]	[217,264,472,141]	9	hSpCas9	negative selection	9164753
148828014	148828037	5	-	27260156	TOV112D	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.12021641594096732	[975]	[935,1204,805,731]	-2	hSpCas9	negative selection	9229033
148827136	148827159	5	+	27260156	TOV112D	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.009276399528481916	[1213]	[1403,1348,1183,1007]	0	hSpCas9	negative selection	9229034
148826893	148826916	5	+	27260156	TOV112D	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	-0.3077204559827189	[97]	[69,139,33,86]	-6	hSpCas9	negative selection	9229035
148827007	148827030	5	-	27260156	TC71	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.23119669409944144	[310]	[327,406,379,455]	6	hSpCas9	negative selection	9286002
148827734	148827757	5	-	27260156	TC71	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.07586519213639564	[900]	[1006,905,1157,994]	2	hSpCas9	negative selection	9286003
148826894	148826917	5	-	27260156	TC71	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.38997561935015	[151]	[223,173,219,236]	8	hSpCas9	negative selection	9286004
148828014	148828037	5	-	27260156	TC71	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.2732686920178232	[975]	[824,795,1062,766]	-6	hSpCas9	negative selection	9350284
148827136	148827159	5	+	27260156	TC71	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	-0.02762494954379391	[1213]	[1312,1126,1157,1526]	0	hSpCas9	negative selection	9350285
148826893	148826916	5	+	27260156	TC71	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.4396536907741586	[97]	[156,98,136,178]	8	hSpCas9	negative selection	9350286
148827007	148827030	5	-	27260156	TC32	viability	CGTCTGCAGACGCTCGAACTTGG	ADRB2	ENSG00000169252	0.41273229567519876	[310]	[436,211,501,467]	7	hSpCas9	negative selection	9407253
148827734	148827757	5	-	27260156	TC32	viability	TGTAAACTTCCTTACGGATGAGG	ADRB2	ENSG00000169252	0.19869844240397716	[900]	[864,883,1132,1020]	3	hSpCas9	negative selection	9407254
148826894	148826917	5	-	27260156	TC32	viability	CCCTTTCCTGCGTGACGTCGTGG	ADRB2	ENSG00000169252	0.9626058061337667	[151]	[273,302,225,272]	9	hSpCas9	negative selection	9407255
148828014	148828037	5	-	27260156	TC32	viability	TGTGAATCAATGTTATCGCTAGG	ADRB2	ENSG00000169252	-0.11083728022797923	[975]	[891,555,1103,950]	-2	hSpCas9	negative selection	9471535
148827136	148827159	5	+	27260156	TC32	viability	GCAACTTCTGGTGCGAGTTTTGG	ADRB2	ENSG00000169252	0.2035072651636496	[1213]	[1251,1103,1638,1321]	3	hSpCas9	negative selection	9471536
148826893	148826916	5	+	27260156	TC32	viability	ACCACGACGTCACGCAGGAAAGG	ADRB2	ENSG00000169252	0.01088936106028715	[97]	[74,54,134,126]	0	hSpCas9	negative selection	9471537
148827001	148827024	5	-	27869803	HPAFII	viability after 27 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.23164326599782226	[347]	[151,158,NaN]	-2	hSpCas9	negative selection	9590548
148827058	148827081	5	-	27869803	HPAFII	viability after 27 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.4629736645442416	[383]	[292,265,NaN]	4	hSpCas9	negative selection	9590549
148827262	148827285	5	+	27869803	HPAFII	viability after 27 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.8403145277562423	[332]	[439,207,NaN]	6	hSpCas9	negative selection	9590550
148827281	148827304	5	-	27869803	HPAFII	viability after 27 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-0.37610193158364935	[124]	[54,46,NaN]	-3	hSpCas9	negative selection	9590551
148827891	148827914	5	+	27869803	HPAFII	viability after 27 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.7688662212612283	[554]	[728,303,NaN]	6	hSpCas9	negative selection	9590552
148827920	148827943	5	+	27869803	HPAFII	viability after 27 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.7123371806761987	[182]	[107,198,NaN]	6	hSpCas9	negative selection	9590553
148827001	148827024	5	-	27869803	HPAFII	viability after 15 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.034425078131566256	[347]	[580,230,NaN]	0	hSpCas9	negative selection	9672997
148827058	148827081	5	-	27869803	HPAFII	viability after 15 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.5155868365456674	[383]	[909,390,NaN]	6	hSpCas9	negative selection	9672998
148827262	148827285	5	+	27869803	HPAFII	viability after 15 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	-0.4314952115603501	[332]	[466,139,NaN]	-5	hSpCas9	negative selection	9672999
148827281	148827304	5	-	27869803	HPAFII	viability after 15 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	0.09285516301987273	[124]	[199,107,NaN]	1	hSpCas9	negative selection	9673000
148827891	148827914	5	+	27869803	HPAFII	viability after 15 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.3584611511073974	[554]	[1101,554,NaN]	4	hSpCas9	negative selection	9673001
148827920	148827943	5	+	27869803	HPAFII	viability after 15 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.5712498990485372	[182]	[179,361,NaN]	6	hSpCas9	negative selection	9673002
148827001	148827024	5	-	27869803	ASPC1	viability after 36 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.8853318111224049	[711]	[755,317,357]	8	hSpCas9	negative selection	9755446
148827058	148827081	5	-	27869803	ASPC1	viability after 36 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.017636476247950617	[1042]	[468,388,277]	0	hSpCas9	negative selection	9755447
148827262	148827285	5	+	27869803	ASPC1	viability after 36 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.21212880929848021	[690]	[508,124,237]	2	hSpCas9	negative selection	9755448
148827281	148827304	5	-	27869803	ASPC1	viability after 36 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-0.26646669269529255	[277]	[24,140,70]	-3	hSpCas9	negative selection	9755449
148827891	148827914	5	+	27869803	ASPC1	viability after 36 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.21679639241286253	[1028]	[586,506,222]	2	hSpCas9	negative selection	9755450
148827920	148827943	5	+	27869803	ASPC1	viability after 36 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.09458065572160146	[508]	[75,144,302]	0	hSpCas9	negative selection	9755451
148827001	148827024	5	-	27869803	PATU8988S	viability after 35 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.08735259744705379	[478]	[217,144,NaN]	-1	hSpCas9	negative selection	9837895
148827058	148827081	5	-	27869803	PATU8988S	viability after 35 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	-0.3347992140644155	[938]	[237,361,NaN]	-4	hSpCas9	negative selection	9837896
148827262	148827285	5	+	27869803	PATU8988S	viability after 35 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.3533723777166713	[553]	[306,262,NaN]	4	hSpCas9	negative selection	9837897
148827281	148827304	5	-	27869803	PATU8988S	viability after 35 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	0.42978382250758695	[211]	[120,108,NaN]	5	hSpCas9	negative selection	9837898
148827891	148827914	5	+	27869803	PATU8988S	viability after 35 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.3120866906118275	[897]	[454,442,NaN]	3	hSpCas9	negative selection	9837899
148827920	148827943	5	+	27869803	PATU8988S	viability after 35 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.7064824502070775	[391]	[313,200,NaN]	7	hSpCas9	negative selection	9837900
148827001	148827024	5	-	27869803	PATU8988S	viability after 31 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.5812436893585282	[478]	[283,287,NaN]	7	hSpCas9	negative selection	9920344
148827058	148827081	5	-	27869803	PATU8988S	viability after 31 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	-0.08521221938777113	[938]	[282,441,NaN]	-1	hSpCas9	negative selection	9920345
148827262	148827285	5	+	27869803	PATU8988S	viability after 31 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.4172185407097068	[553]	[217,392,NaN]	5	hSpCas9	negative selection	9920346
148827281	148827304	5	-	27869803	PATU8988S	viability after 31 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	0.1622942662425284	[211]	[87,102,NaN]	2	hSpCas9	negative selection	9920347
148827891	148827914	5	+	27869803	PATU8988S	viability after 31 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.301776118515077	[897]	[348,558,NaN]	4	hSpCas9	negative selection	9920348
148827920	148827943	5	+	27869803	PATU8988S	viability after 31 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	1.3486203177924543	[391]	[328,485,NaN]	9	hSpCas9	negative selection	9920349
148827001	148827024	5	-	27869803	HPAFII	viability after 35 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-1.120441854614761	[347]	[25,142,NaN]	-6	hSpCas9	negative selection	10002793
148827058	148827081	5	-	27869803	HPAFII	viability after 35 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.7734874112345643	[383]	[233,442,NaN]	5	hSpCas9	negative selection	10002794
148827262	148827285	5	+	27869803	HPAFII	viability after 35 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.4408428291715312	[332]	[360,79,NaN]	3	hSpCas9	negative selection	10002795
148827281	148827304	5	-	27869803	HPAFII	viability after 35 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-1.3296116492160597	[124]	[27,21,NaN]	-6	hSpCas9	negative selection	10002796
148827891	148827914	5	+	27869803	HPAFII	viability after 35 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	1.2276277009004948	[554]	[839,452,NaN]	8	hSpCas9	negative selection	10002797
148827920	148827943	5	+	27869803	HPAFII	viability after 35 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.9861648004723464	[182]	[159,209,NaN]	6	hSpCas9	negative selection	10002798
148827001	148827024	5	-	27869803	HPAFII	viability after 31 days	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-1.0401506463480925	[347]	[71,119,NaN]	-6	hSpCas9	negative selection	10085242
148827058	148827081	5	-	27869803	HPAFII	viability after 31 days	GCCCATGACCAGATCAGCACAGG	ADRB2	ENSG00000169252	0.6592234420867814	[383]	[291,392,NaN]	5	hSpCas9	negative selection	10085243
148827262	148827285	5	+	27869803	HPAFII	viability after 31 days	TGCTGACCAAGAATAAGGCCCGG	ADRB2	ENSG00000169252	0.12651920010271228	[332]	[315,81,NaN]	0	hSpCas9	negative selection	10085244
148827281	148827304	5	-	27869803	HPAFII	viability after 31 days	ACACCATCAGAATGATCACCCGG	ADRB2	ENSG00000169252	-1.7162489202537017	[124]	[17,24,NaN]	-7	hSpCas9	negative selection	10085245
148827891	148827914	5	+	27869803	HPAFII	viability after 31 days	TACTCCAGCAACGGCAACACAGG	ADRB2	ENSG00000169252	0.9949289858905133	[554]	[782,443,NaN]	7	hSpCas9	negative selection	10085246
148827920	148827943	5	+	27869803	HPAFII	viability after 31 days	GAGTGGATATCACGTGGAACAGG	ADRB2	ENSG00000169252	0.6749091560459771	[182]	[151,176,NaN]	5	hSpCas9	negative selection	10085247
148827197	148827220	5	+	28162770	P31FUJ	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	-0.05119539792443076	[245]	[278]	0	hSpCas9	negative selection	10107744
148827882	148827905	5	+	28162770	P31FUJ	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	0.12976787497032954	[244]	[314]	1	hSpCas9	negative selection	10107745
148827430	148827453	5	-	28162770	P31FUJ	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-1.0717397716818624	[253]	[141]	-6	hSpCas9	negative selection	10107746
148827442	148827465	5	-	28162770	P31FUJ	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	-0.032503553928547646	[46]	[53]	0	hSpCas9	negative selection	10107747
148827679	148827702	5	-	28162770	P31FUJ	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.15814967634015215	[150]	[197]	1	hSpCas9	negative selection	10107748
148826888	148826911	5	+	28162770	P31FUJ	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.9245541235248782	[268]	[599]	9	hSpCas9	negative selection	10107749
148827001	148827024	5	-	28162770	P31FUJ	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	1.0782192821508767	[238]	[592]	9	hSpCas9	negative selection	10107750
148827317	148827340	5	-	28162770	P31FUJ	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	-0.06527171811244895	[267]	[300]	0	hSpCas9	negative selection	10107751
148827462	148827485	5	-	28162770	P31FUJ	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.20920234246473446	[476]	[647]	2	hSpCas9	negative selection	10107752
148827545	148827568	5	-	28162770	P31FUJ	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	0.16364783373929492	[331]	[436]	1	hSpCas9	negative selection	10107753
148827197	148827220	5	+	28162770	TF1	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10277110
148827882	148827905	5	+	28162770	TF1	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	NaN	[NaN]	[312]	1	hSpCas9	negative selection	10277111
148827430	148827453	5	-	28162770	TF1	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	NaN	[NaN]	[156]	1	hSpCas9	negative selection	10277112
148827442	148827465	5	-	28162770	TF1	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10277113
148827679	148827702	5	-	28162770	TF1	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10277114
148826888	148826911	5	+	28162770	TF1	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	NaN	[NaN]	[371]	1	hSpCas9	negative selection	10277115
148827001	148827024	5	-	28162770	TF1	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	NaN	[NaN]	[203]	1	hSpCas9	negative selection	10277116
148827317	148827340	5	-	28162770	TF1	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	NaN	[NaN]	[293]	1	hSpCas9	negative selection	10277117
148827462	148827485	5	-	28162770	TF1	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	NaN	[NaN]	[679]	1	hSpCas9	negative selection	10277118
148827545	148827568	5	-	28162770	TF1	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	NaN	[NaN]	[322]	1	hSpCas9	negative selection	10277119
148827197	148827220	5	+	28162770	SKM1	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	0.743331995950218	[73]	[218]	7	hSpCas9	negative selection	10446476
148827882	148827905	5	+	28162770	SKM1	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	1.5549677604233187	[35]	[186]	9	hSpCas9	negative selection	10446477
148827430	148827453	5	-	28162770	SKM1	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.8526984952449218	[94]	[92]	-6	hSpCas9	negative selection	10446478
148827442	148827465	5	-	28162770	SKM1	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	0.44808746534573896	[16]	[40]	4	hSpCas9	negative selection	10446479
148827679	148827702	5	-	28162770	SKM1	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.6942480526151364	[42]	[122]	6	hSpCas9	negative selection	10446480
148826888	148826911	5	+	28162770	SKM1	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.6336777857541842	[104]	[287]	6	hSpCas9	negative selection	10446481
148827001	148827024	5	-	28162770	SKM1	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.0835336179745021	[70]	[132]	0	hSpCas9	negative selection	10446482
148827317	148827340	5	-	28162770	SKM1	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.08070110062307945	[68]	[128]	0	hSpCas9	negative selection	10446483
148827462	148827485	5	-	28162770	SKM1	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.3217337794394439	[104]	[231]	3	hSpCas9	negative selection	10446484
148827545	148827568	5	-	28162770	SKM1	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	0.221852591567422	[80]	[166]	2	hSpCas9	negative selection	10446485
148827197	148827220	5	+	28162770	SKM1	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	0.743331995950218	[73]	[218]	7	hSpCas9	negative selection	10615842
148827882	148827905	5	+	28162770	SKM1	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	1.5549677604233187	[35]	[186]	9	hSpCas9	negative selection	10615843
148827430	148827453	5	-	28162770	SKM1	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.8526984952449218	[94]	[92]	-6	hSpCas9	negative selection	10615844
148827442	148827465	5	-	28162770	SKM1	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	0.44808746534573896	[16]	[40]	4	hSpCas9	negative selection	10615845
148827679	148827702	5	-	28162770	SKM1	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.6942480526151364	[42]	[122]	6	hSpCas9	negative selection	10615846
148826888	148826911	5	+	28162770	SKM1	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.6336777857541842	[104]	[287]	6	hSpCas9	negative selection	10615847
148827001	148827024	5	-	28162770	SKM1	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.0835336179745021	[70]	[132]	0	hSpCas9	negative selection	10615848
148827317	148827340	5	-	28162770	SKM1	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.08070110062307945	[68]	[128]	0	hSpCas9	negative selection	10615849
148827462	148827485	5	-	28162770	SKM1	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.3217337794394439	[104]	[231]	3	hSpCas9	negative selection	10615850
148827545	148827568	5	-	28162770	SKM1	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	0.221852591567422	[80]	[166]	2	hSpCas9	negative selection	10615851
148827197	148827220	5	+	28162770	PL21	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	0.8888251936268099	[236]	[190]	7	hSpCas9	negative selection	10785208
148827882	148827905	5	+	28162770	PL21	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	-0.05428166103976553	[166]	[69]	0	hSpCas9	negative selection	10785209
148827430	148827453	5	-	28162770	PL21	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.09226939347798724	[386]	[157]	0	hSpCas9	negative selection	10785210
148827442	148827465	5	-	28162770	PL21	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	-0.5572900822366016	[70]	[20]	-4	hSpCas9	negative selection	10785211
148827679	148827702	5	-	28162770	PL21	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.2970011537419091	[143]	[76]	2	hSpCas9	negative selection	10785212
148826888	148826911	5	+	28162770	PL21	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.8455667564743705	[256]	[200]	7	hSpCas9	negative selection	10785213
148827001	148827024	5	-	28162770	PL21	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.7121226698533706	[222]	[158]	6	hSpCas9	negative selection	10785214
148827317	148827340	5	-	28162770	PL21	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	-0.26524127047916346	[242]	[87]	-2	hSpCas9	negative selection	10785215
148827462	148827485	5	-	28162770	PL21	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.4207990686013128	[356]	[207]	3	hSpCas9	negative selection	10785216
148827545	148827568	5	-	28162770	PL21	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	-0.7540566958975552	[216]	[55]	-5	hSpCas9	negative selection	10785217
148827197	148827220	5	+	28162770	P31FUJ	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	-0.05119539792443076	[245]	[278]	0	hSpCas9	negative selection	10954574
148827882	148827905	5	+	28162770	P31FUJ	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	0.12976787497032954	[244]	[314]	1	hSpCas9	negative selection	10954575
148827430	148827453	5	-	28162770	P31FUJ	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-1.0717397716818624	[253]	[141]	-6	hSpCas9	negative selection	10954576
148827442	148827465	5	-	28162770	P31FUJ	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	-0.032503553928547646	[46]	[53]	0	hSpCas9	negative selection	10954577
148827679	148827702	5	-	28162770	P31FUJ	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.15814967634015215	[150]	[197]	1	hSpCas9	negative selection	10954578
148826888	148826911	5	+	28162770	P31FUJ	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.9245541235248782	[268]	[599]	9	hSpCas9	negative selection	10954579
148827001	148827024	5	-	28162770	P31FUJ	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	1.0782192821508767	[238]	[592]	9	hSpCas9	negative selection	10954580
148827317	148827340	5	-	28162770	P31FUJ	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	-0.06527171811244895	[267]	[300]	0	hSpCas9	negative selection	10954581
148827462	148827485	5	-	28162770	P31FUJ	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.20920234246473446	[476]	[647]	2	hSpCas9	negative selection	10954582
148827545	148827568	5	-	28162770	P31FUJ	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	0.16364783373929492	[331]	[436]	1	hSpCas9	negative selection	10954583
148827197	148827220	5	+	28162770	OCIAML5	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	-0.3939603496932672	[98]	[135]	-3	hSpCas9	negative selection	11123940
148827882	148827905	5	+	28162770	OCIAML5	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	0.5891232162708152	[122]	[333]	5	hSpCas9	negative selection	11123941
148827430	148827453	5	-	28162770	OCIAML5	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-1.2130642304299517	[130]	[101]	-6	hSpCas9	negative selection	11123942
148827442	148827465	5	-	28162770	OCIAML5	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	-0.1216736306212769	[43]	[72]	-1	hSpCas9	negative selection	11123943
148827679	148827702	5	-	28162770	OCIAML5	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	1.549449788761228	[66]	[353]	9	hSpCas9	negative selection	11123944
148826888	148826911	5	+	28162770	OCIAML5	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	1.1758874907070045	[114]	[468]	8	hSpCas9	negative selection	11123945
148827001	148827024	5	-	28162770	OCIAML5	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.2295718981603604	[145]	[308]	2	hSpCas9	negative selection	11123946
148827317	148827340	5	-	28162770	OCIAML5	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.42001297457280384	[105]	[255]	3	hSpCas9	negative selection	11123947
148827462	148827485	5	-	28162770	OCIAML5	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.29559681910615976	[282]	[626]	2	hSpCas9	negative selection	11123948
148827545	148827568	5	-	28162770	OCIAML5	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	-0.7558512556046937	[260]	[278]	-5	hSpCas9	negative selection	11123949
148827197	148827220	5	+	28162770	EOL1	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	-0.39563054136686804	[411]	[164]	-3	hSpCas9	negative selection	11293306
148827882	148827905	5	+	28162770	EOL1	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	0.563800427792644	[225]	[175]	5	hSpCas9	negative selection	11293307
148827430	148827453	5	-	28162770	EOL1	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.6552064381478605	[552]	[184]	-5	hSpCas9	negative selection	11293308
148827442	148827465	5	-	28162770	EOL1	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	1.2882960421525238	[135]	[174]	9	hSpCas9	negative selection	11293309
148827679	148827702	5	-	28162770	EOL1	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.12785583257580374	[336]	[193]	1	hSpCas9	negative selection	11293310
148826888	148826911	5	+	28162770	EOL1	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.7294948571178033	[513]	[448]	6	hSpCas9	negative selection	11293311
148827001	148827024	5	-	28162770	EOL1	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.6232999295228471	[328]	[266]	5	hSpCas9	negative selection	11293312
148827317	148827340	5	-	28162770	EOL1	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.16662255876868237	[207]	[122]	1	hSpCas9	negative selection	11293313
148827462	148827485	5	-	28162770	EOL1	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.9218023948317172	[525]	[524]	7	hSpCas9	negative selection	11293314
148827545	148827568	5	-	28162770	EOL1	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	-0.017825410847410003	[318]	[165]	0	hSpCas9	negative selection	11293315
148827197	148827220	5	+	28162770	MOLM13	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	1.879386523118174	[305]	[813]	9	hSpCas9	negative selection	11462672
148827882	148827905	5	+	28162770	MOLM13	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	0.12096690719034688	[261]	[205]	0	hSpCas9	negative selection	11462673
148827430	148827453	5	-	28162770	MOLM13	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	1.1295542505953375	[408]	[646]	8	hSpCas9	negative selection	11462674
148827442	148827465	5	-	28162770	MOLM13	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	1.8051927023188572	[111]	[282]	9	hSpCas9	negative selection	11462675
148827679	148827702	5	-	28162770	MOLM13	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.78770981346995	[273]	[341]	6	hSpCas9	negative selection	11462676
148826888	148826911	5	+	28162770	MOLM13	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	1.189117572356816	[423]	[698]	8	hSpCas9	negative selection	11462677
148827001	148827024	5	-	28162770	MOLM13	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.021994797392424714	[388]	[276]	0	hSpCas9	negative selection	11462678
148827317	148827340	5	-	28162770	MOLM13	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.417703624376362	[233]	[225]	3	hSpCas9	negative selection	11462679
148827462	148827485	5	-	28162770	MOLM13	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.36901413146177264	[467]	[436]	2	hSpCas9	negative selection	11462680
148827545	148827568	5	-	28162770	MOLM13	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	-0.46614735607706237	[341]	[178]	-3	hSpCas9	negative selection	11462681
148827197	148827220	5	+	28162770	HEL	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	0.34829147353510154	[324]	[264]	3	hSpCas9	negative selection	11632038
148827882	148827905	5	+	28162770	HEL	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	-0.01884495032371175	[173]	[109]	0	hSpCas9	negative selection	11632039
148827430	148827453	5	-	28162770	HEL	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.31123263695523806	[400]	[206]	-2	hSpCas9	negative selection	11632040
148827442	148827465	5	-	28162770	HEL	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	0.6578457243905652	[94]	[95]	5	hSpCas9	negative selection	11632041
148827679	148827702	5	-	28162770	HEL	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.7232287498607248	[243]	[257]	6	hSpCas9	negative selection	11632042
148826888	148826911	5	+	28162770	HEL	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	1.1925448873078968	[359]	[526]	9	hSpCas9	negative selection	11632043
148827001	148827024	5	-	28162770	HEL	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.6712140006108345	[300]	[306]	6	hSpCas9	negative selection	11632044
148827317	148827340	5	-	28162770	HEL	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	-0.842687995169885	[237]	[84]	-5	hSpCas9	negative selection	11632045
148827462	148827485	5	-	28162770	HEL	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	-0.19886030335644256	[404]	[225]	-1	hSpCas9	negative selection	11632046
148827545	148827568	5	-	28162770	HEL	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	0.48200300201270496	[312]	[279]	4	hSpCas9	negative selection	11632047
148827197	148827220	5	+	28162770	MV411	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	1.6100076301674835	[216]	[557]	9	hSpCas9	negative selection	11801404
148827882	148827905	5	+	28162770	MV411	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	1.0453937748381297	[175]	[305]	8	hSpCas9	negative selection	11801405
148827430	148827453	5	-	28162770	MV411	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	0.48261215215557807	[304]	[358]	4	hSpCas9	negative selection	11801406
148827442	148827465	5	-	28162770	MV411	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	1.801239120017471	[77]	[228]	9	hSpCas9	negative selection	11801407
148827679	148827702	5	-	28162770	MV411	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	-0.2204855287481615	[212]	[153]	-2	hSpCas9	negative selection	11801408
148826888	148826911	5	+	28162770	MV411	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.8371535814745661	[302]	[455]	7	hSpCas9	negative selection	11801409
148827001	148827024	5	-	28162770	MV411	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	1.727430491902389	[170]	[476]	9	hSpCas9	negative selection	11801410
148827317	148827340	5	-	28162770	MV411	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.5865261968283204	[233]	[295]	5	hSpCas9	negative selection	11801411
148827462	148827485	5	-	28162770	MV411	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.6828236954534215	[351]	[475]	6	hSpCas9	negative selection	11801412
148827545	148827568	5	-	28162770	MV411	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	1.608774030228373	[194]	[500]	9	hSpCas9	negative selection	11801413
148827197	148827220	5	+	28162770	MONOMAC1	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	-0.4133547539863174	[157]	[135]	-4	hSpCas9	negative selection	11970770
148827882	148827905	5	+	28162770	MONOMAC1	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	0.49578164342227027	[72]	[117]	5	hSpCas9	negative selection	11970771
148827430	148827453	5	-	28162770	MONOMAC1	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.07455284053455868	[236]	[257]	0	hSpCas9	negative selection	11970772
148827442	148827465	5	-	28162770	MONOMAC1	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	-0.5314558861301131	[28]	[22]	-4	hSpCas9	negative selection	11970773
148827679	148827702	5	-	28162770	MONOMAC1	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.2527660703799667	[122]	[167]	2	hSpCas9	negative selection	11970774
148826888	148826911	5	+	28162770	MONOMAC1	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.8609687563760117	[194]	[405]	7	hSpCas9	negative selection	11970775
148827001	148827024	5	-	28162770	MONOMAC1	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.35045094824293954	[155]	[227]	3	hSpCas9	negative selection	11970776
148827317	148827340	5	-	28162770	MONOMAC1	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.08863536245397194	[136]	[166]	0	hSpCas9	negative selection	11970777
148827462	148827485	5	-	28162770	MONOMAC1	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.36484204054856106	[251]	[371]	3	hSpCas9	negative selection	11970778
148827545	148827568	5	-	28162770	MONOMAC1	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	0.593040083566215	[143]	[248]	6	hSpCas9	negative selection	11970779
148827197	148827220	5	+	28162770	OCIAML2	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	0.6436663073464486	[46]	[406]	6	hSpCas9	negative selection	12140136
148827882	148827905	5	+	28162770	OCIAML2	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	0.007417471562483013	[27]	[155]	0	hSpCas9	negative selection	12140137
148827430	148827453	5	-	28162770	OCIAML2	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.7274052406042728	[68]	[230]	-5	hSpCas9	negative selection	12140138
148827442	148827465	5	-	28162770	OCIAML2	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	1.3019596786547663	[8]	[122]	9	hSpCas9	negative selection	12140139
148827679	148827702	5	-	28162770	OCIAML2	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	0.6013200166368537	[21]	[184]	6	hSpCas9	negative selection	12140140
148826888	148826911	5	+	28162770	OCIAML2	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.0227022000134266	[64]	[365]	0	hSpCas9	negative selection	12140141
148827001	148827024	5	-	28162770	OCIAML2	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	0.958878156845016	[30]	[333]	8	hSpCas9	negative selection	12140142
148827317	148827340	5	-	28162770	OCIAML2	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	0.04721847962045799	[32]	[188]	0	hSpCas9	negative selection	12140143
148827462	148827485	5	-	28162770	OCIAML2	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	0.45714813684018096	[63]	[486]	4	hSpCas9	negative selection	12140144
148827545	148827568	5	-	28162770	OCIAML2	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	0.06542307499804856	[44]	[260]	0	hSpCas9	negative selection	12140145
148827197	148827220	5	+	28162770	OCIAML3	viability	GACCCTGTGCGTGATCGCAGTGG	ADRB2	ENSG00000169252	0.1318173962368427	[64]	[214]	1	hSpCas9	negative selection	12309502
148827882	148827905	5	+	28162770	OCIAML3	viability	GGGAATGGCTACTCCAGCAACGG	ADRB2	ENSG00000169252	-0.6354275677041439	[52]	[102]	-5	hSpCas9	negative selection	12309503
148827430	148827453	5	-	28162770	OCIAML3	viability	GGACACGATGGAAGAGGCAATGG	ADRB2	ENSG00000169252	-0.6600968307819355	[66]	[127]	-5	hSpCas9	negative selection	12309504
148827442	148827465	5	-	28162770	OCIAML3	viability	GGGAACGTAGAAGGACACGATGG	ADRB2	ENSG00000169252	2.3128829552843553	[6]	[104]	9	hSpCas9	negative selection	12309505
148827679	148827702	5	-	28162770	OCIAML3	viability	GAAGAAGGGCAGCCAGCAGAGGG	ADRB2	ENSG00000169252	-2.088772332073741	[61]	[43]	-8	hSpCas9	negative selection	12309506
148826888	148826911	5	+	28162770	OCIAML3	viability	GCCGGACCACGACGTCACGCAGG	ADRB2	ENSG00000169252	0.3285878559902302	[66]	[253]	3	hSpCas9	negative selection	12309507
148827001	148827024	5	-	28162770	OCIAML3	viability	CAGACGCTCGAACTTGGCAATGG	ADRB2	ENSG00000169252	-0.10067561506857511	[64]	[182]	-1	hSpCas9	negative selection	12309508
148827317	148827340	5	-	28162770	OCIAML3	viability	GAATGGGCAAGAAGGAGGTAAGG	ADRB2	ENSG00000169252	-0.0634929236253834	[53]	[155]	0	hSpCas9	negative selection	12309509
148827462	148827485	5	-	28162770	OCIAML3	viability	ACGAAGACCATGATCACCAGGGG	ADRB2	ENSG00000169252	-0.6924113443851577	[90]	[169]	-5	hSpCas9	negative selection	12309510
148827545	148827568	5	-	28162770	OCIAML3	viability	TAAGGTTCTGGACATGGAAGCGG	ADRB2	ENSG00000169252	0.2326607567902751	[52]	[187]	2	hSpCas9	negative selection	12309511