Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:155
• Symbol:ADRB3
• Description:adrenoceptor beta 3

DataSource: http://genomecrispr.dkfz.de/#!/results/ADRB3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
37965951	37965974	8	+	26472758	Jiyoye	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.9847204106645465	[64]	[96]	6	hSpCas9	negative selection	3499
37965791	37965814	8	-	26472758	Jiyoye	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	3.4071753815058727	[0]	[7]	9	hSpCas9	negative selection	3500
37966266	37966289	8	+	26472758	Jiyoye	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.13169070462582877	[76]	[52]	-1	hSpCas9	negative selection	3501
37966164	37966187	8	+	26472758	Jiyoye	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.6544636842865124	[262]	[125]	-5	hSpCas9	negative selection	3502
37966131	37966154	8	-	26472758	Jiyoye	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	1.3875465747569409	[36]	[72]	8	hSpCas9	negative selection	3503
37966083	37966106	8	+	26472758	Jiyoye	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.058973592409402364	[470]	[369]	0	hSpCas9	negative selection	3504
37965968	37965991	8	-	26472758	Jiyoye	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	1.5167998726803715	[37]	[81]	8	hSpCas9	negative selection	3505
37965871	37965894	8	+	26472758	Jiyoye	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	-0.3406375948973252	[177]	[105]	-2	hSpCas9	negative selection	3506
37965840	37965863	8	+	26472758	Jiyoye	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.6284485282248478	[40]	[19]	-4	hSpCas9	negative selection	3507
37965825	37965848	8	+	26472758	Jiyoye	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.6312987663087625	[75]	[36]	-4	hSpCas9	negative selection	3508
37965951	37965974	8	+	26472758	KBM7	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	-0.6854742834656122	[278,180]	[82,50]	-5	hSpCas9	negative selection	194617
37965791	37965814	8	-	26472758	KBM7	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	0.3986914629046523	[31,35]	[24,17]	4	hSpCas9	negative selection	194618
37966266	37966289	8	+	26472758	KBM7	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-1.2387990175936896	[466,291]	[79,68]	-7	hSpCas9	negative selection	194619
37966164	37966187	8	+	26472758	KBM7	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.9783464780052472	[1207,1207]	[304,275]	-6	hSpCas9	negative selection	194620
37966131	37966154	8	-	26472758	KBM7	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	-0.12659003362027588	[262,230]	[111,100]	-1	hSpCas9	negative selection	194621
37966083	37966106	8	+	26472758	KBM7	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.5309825239424524	[1339,957]	[796,747]	6	hSpCas9	negative selection	194622
37965968	37965991	8	-	26472758	KBM7	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.46590517024460415	[466,265]	[175,282]	5	hSpCas9	negative selection	194623
37965871	37965894	8	+	26472758	KBM7	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.1772486972949786	[502,604]	[246,344]	1	hSpCas9	negative selection	194624
37965840	37965863	8	+	26472758	KBM7	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.9038102166607596	[237,128]	[64,26]	-6	hSpCas9	negative selection	194625
37965825	37965848	8	+	26472758	KBM7	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.34927362972706355	[248,372]	[66,162]	-3	hSpCas9	negative selection	194626
37965951	37965974	8	+	26472758	Raji	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	1.0402693395150626	[87]	[41]	8	hSpCas9	negative selection	385735
37965791	37965814	8	-	26472758	Raji	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	3.1073835353735992	[0]	[1]	9	hSpCas9	negative selection	385736
37966266	37966289	8	+	26472758	Raji	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	0.9781005184286329	[139]	[63]	8	hSpCas9	negative selection	385737
37966164	37966187	8	+	26472758	Raji	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.5962234618461757	[455]	[69]	-5	hSpCas9	negative selection	385738
37966131	37966154	8	-	26472758	Raji	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.9042916699960879	[98]	[42]	8	hSpCas9	negative selection	385739
37966083	37966106	8	+	26472758	Raji	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.7419538018496508	[504]	[195]	7	hSpCas9	negative selection	385740
37965968	37965991	8	-	26472758	Raji	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.37355764873796055	[152]	[45]	3	hSpCas9	negative selection	385741
37965871	37965894	8	+	26472758	Raji	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.29565017280542094	[164]	[46]	3	hSpCas9	negative selection	385742
37965840	37965863	8	+	26472758	Raji	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.45740108340992636	[141]	[23]	-4	hSpCas9	negative selection	385743
37965825	37965848	8	+	26472758	Raji	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.9011784781298244	[168]	[20]	-6	hSpCas9	negative selection	385744
37965951	37965974	8	+	26472758	K562	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.7542797731468842	[183]	[261]	6	hSpCas9	negative selection	576853
37965791	37965814	8	-	26472758	K562	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	-0.5711567011961258	[43]	[24]	-4	hSpCas9	negative selection	576854
37966266	37966289	8	+	26472758	K562	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.5374011022840196	[293]	[170]	-3	hSpCas9	negative selection	576855
37966164	37966187	8	+	26472758	K562	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-1.546485673610563	[871]	[251]	-6	hSpCas9	negative selection	576856
37966131	37966154	8	-	26472758	K562	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	1.088682915345067	[214]	[385]	8	hSpCas9	negative selection	576857
37966083	37966106	8	+	26472758	K562	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.5306631726611344	[965]	[1177]	4	hSpCas9	negative selection	576858
37965968	37965991	8	-	26472758	K562	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.707152968976587	[237]	[327]	6	hSpCas9	negative selection	576859
37965871	37965894	8	+	26472758	K562	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.14739427327158222	[368]	[344]	1	hSpCas9	negative selection	576860
37965840	37965863	8	+	26472758	K562	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.10022944372099918	[159]	[125]	0	hSpCas9	negative selection	576861
37965825	37965848	8	+	26472758	K562	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-1.4832090019204234	[307]	[92]	-6	hSpCas9	negative selection	576862
37965264	37965287	8	-	26627737	DLD1	viability	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	1.0828170262019472	[92]	[46,56,77]	8	hSpCas9	negative selection	839441
37965377	37965400	8	+	26627737	DLD1	viability	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.5046129588451325	[311]	[54,48,96]	-5	hSpCas9	negative selection	839442
37965802	37965825	8	+	26627737	DLD1	viability	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.39522191861879874	[838]	[266,319,40]	-4	hSpCas9	negative selection	839443
37965939	37965962	8	-	26627737	DLD1	viability	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	1.0127868076987094	[452]	[280,235,330]	8	hSpCas9	negative selection	839444
37965264	37965287	8	-	26627737	GBM cells	viability after 5 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	-0.39654200864048583	[80]	[23,41]	-6	hSpCas9	negative selection	921756
37965377	37965400	8	+	26627737	GBM cells	viability after 5 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.114181861788752	[173]	[103,97]	1	hSpCas9	negative selection	921757
37965802	37965825	8	+	26627737	GBM cells	viability after 5 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.18310864031099428	[578]	[300,245]	-3	hSpCas9	negative selection	921758
37965939	37965962	8	-	26627737	GBM cells	viability after 5 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.30298025634352643	[296]	[244,147]	5	hSpCas9	negative selection	921759
37965264	37965287	8	-	26627737	GBM cells	viability after 13 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	-0.5308404783213798	[80]	[41,20]	-6	hSpCas9	negative selection	1004071
37965377	37965400	8	+	26627737	GBM cells	viability after 13 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.09411149419251735	[173]	[129,76]	1	hSpCas9	negative selection	1004072
37965802	37965825	8	+	26627737	GBM cells	viability after 13 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.12454449080526975	[578]	[355,232]	-1	hSpCas9	negative selection	1004073
37965939	37965962	8	-	26627737	GBM cells	viability after 13 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.3944028829070929	[296]	[320,122]	5	hSpCas9	negative selection	1004074
37965264	37965287	8	-	26627737	GBM cells	viability after 21 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	-1.034843877387405	[80]	[21,20]	-7	hSpCas9	negative selection	1086386
37965377	37965400	8	+	26627737	GBM cells	viability after 21 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.5405776121789521	[173]	[113,158]	5	hSpCas9	negative selection	1086387
37965802	37965825	8	+	26627737	GBM cells	viability after 21 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.09775275041105136	[578]	[380,295]	1	hSpCas9	negative selection	1086388
37965939	37965962	8	-	26627737	GBM cells	viability after 21 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.6910537410934008	[296]	[283,238]	7	hSpCas9	negative selection	1086389
37965264	37965287	8	-	26627737	RPE1	viability after 9 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	0.8419994920358331	[243]	[101,181]	5	hSpCas9	negative selection	1168701
37965377	37965400	8	+	26627737	RPE1	viability after 9 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.28256929604598746	[834]	[334,295]	2	hSpCas9	negative selection	1168702
37965802	37965825	8	+	26627737	RPE1	viability after 9 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.47895594992795437	[1357]	[263,357]	-3	hSpCas9	negative selection	1168703
37965939	37965962	8	-	26627737	RPE1	viability after 9 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.7572982843031069	[787]	[354,496]	5	hSpCas9	negative selection	1168704
37965264	37965287	8	-	26627737	RPE1	viability after 12 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	0.595146996325455	[243]	[99,97]	4	hSpCas9	negative selection	1251016
37965377	37965400	8	+	26627737	RPE1	viability after 12 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.20298384903776018	[834]	[231,285]	1	hSpCas9	negative selection	1251017
37965802	37965825	8	+	26627737	RPE1	viability after 12 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.20281732243218675	[1357]	[333,298]	-1	hSpCas9	negative selection	1251018
37965939	37965962	8	-	26627737	RPE1	viability after 12 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.011475958153824035	[787]	[260,162]	0	hSpCas9	negative selection	1251019
37965264	37965287	8	-	26627737	RPE1	viability after 15 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	0.828182277474735	[243]	[119,124]	5	hSpCas9	negative selection	1333331
37965377	37965400	8	+	26627737	RPE1	viability after 15 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.05455184475687598	[834]	[199,288]	0	hSpCas9	negative selection	1333332
37965802	37965825	8	+	26627737	RPE1	viability after 15 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.5720414726771909	[1357]	[291,225]	-4	hSpCas9	negative selection	1333333
37965939	37965962	8	-	26627737	RPE1	viability after 15 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.8404245588935852	[787]	[475,324]	5	hSpCas9	negative selection	1333334
37965264	37965287	8	-	26627737	RPE1	viability after 18 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	1.3353289595740936	[243]	[126,207]	7	hSpCas9	negative selection	1415646
37965377	37965400	8	+	26627737	RPE1	viability after 18 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.042051522955128644	[834]	[214,222]	0	hSpCas9	negative selection	1415647
37965802	37965825	8	+	26627737	RPE1	viability after 18 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.07145252296510807	[1357]	[343,428]	0	hSpCas9	negative selection	1415648
37965939	37965962	8	-	26627737	RPE1	viability after 18 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.9157908278819797	[787]	[406,394]	5	hSpCas9	negative selection	1415649
37965264	37965287	8	-	26627737	HeLa	viability after 8 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	0.28228566041435854	[198]	[70,96,137]	2	hSpCas9	negative selection	1497961
37965377	37965400	8	+	26627737	HeLa	viability after 8 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.6254254748826634	[413]	[301,332,208]	5	hSpCas9	negative selection	1497962
37965802	37965825	8	+	26627737	HeLa	viability after 8 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.7138764858244604	[701]	[212,200,152]	-6	hSpCas9	negative selection	1497963
37965939	37965962	8	-	26627737	HeLa	viability after 8 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.09108838770622474	[843]	[304,455,269]	-1	hSpCas9	negative selection	1497964
37965264	37965287	8	-	26627737	HeLa	viability after 12 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	0.1489626935219519	[198]	[41,148,74]	1	hSpCas9	negative selection	1580276
37965377	37965400	8	+	26627737	HeLa	viability after 12 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.6330315030183379	[413]	[103,79,149]	-5	hSpCas9	negative selection	1580277
37965802	37965825	8	+	26627737	HeLa	viability after 12 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.2588955560756805	[701]	[186,258,277]	-2	hSpCas9	negative selection	1580278
37965939	37965962	8	-	26627737	HeLa	viability after 12 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.1715756361517825	[843]	[349,292,288]	-1	hSpCas9	negative selection	1580279
37965264	37965287	8	-	26627737	HeLa	viability after 15 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	-1.360216868613092	[198]	[14,58,19]	-8	hSpCas9	negative selection	1662591
37965377	37965400	8	+	26627737	HeLa	viability after 15 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.20004545505859933	[413]	[154,150,132]	-2	hSpCas9	negative selection	1662592
37965802	37965825	8	+	26627737	HeLa	viability after 15 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.019539542373975594	[701]	[320,301,241]	0	hSpCas9	negative selection	1662593
37965939	37965962	8	-	26627737	HeLa	viability after 15 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.8175379469035435	[843]	[223,231,122]	-6	hSpCas9	negative selection	1662594
37965264	37965287	8	-	26627737	HeLa	viability after 18 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	-1.303692623805357	[198]	[9,51,19]	-8	hSpCas9	negative selection	1744906
37965377	37965400	8	+	26627737	HeLa	viability after 18 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.13590428053200748	[413]	[112,129,132]	-1	hSpCas9	negative selection	1744907
37965802	37965825	8	+	26627737	HeLa	viability after 18 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.05236668621550977	[701]	[225,252,241]	0	hSpCas9	negative selection	1744908
37965939	37965962	8	-	26627737	HeLa	viability after 18 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.8342913160201049	[843]	[145,191,122]	-6	hSpCas9	negative selection	1744909
37965264	37965287	8	-	26627737	HCT116	viability after 6 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	-1.5714919189165573	[441]	[14,27]	-7	hSpCas9	negative selection	1827221
37965377	37965400	8	+	26627737	HCT116	viability after 6 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.3740908320724092	[600]	[222,66]	2	hSpCas9	negative selection	1827222
37965802	37965825	8	+	26627737	HCT116	viability after 6 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.7178737472191501	[1294]	[262,46]	-4	hSpCas9	negative selection	1827223
37965939	37965962	8	-	26627737	HCT116	viability after 6 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.3281868927830065	[957]	[215,66]	-2	hSpCas9	negative selection	1827224
37965264	37965287	8	-	26627737	HCT116	viability after 8 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	2.3631820507122026	[40]	[112,147,87]	9	hSpCas9	negative selection	1909536
37965377	37965400	8	+	26627737	HCT116	viability after 8 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.2197698126651992	[302]	[181,121,126]	-3	hSpCas9	negative selection	1909537
37965802	37965825	8	+	26627737	HCT116	viability after 8 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.3362099293924674	[442]	[399,288,237]	3	hSpCas9	negative selection	1909538
37965939	37965962	8	-	26627737	HCT116	viability after 8 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.2032543070875702	[468]	[242,144,284]	-2	hSpCas9	negative selection	1909539
37965264	37965287	8	-	26627737	HCT116	viability after 9 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	-1.636354015570763	[441]	[23,48]	-8	hSpCas9	negative selection	1991851
37965377	37965400	8	+	26627737	HCT116	viability after 9 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-1.2514389851569965	[600]	[53,77]	-7	hSpCas9	negative selection	1991852
37965802	37965825	8	+	26627737	HCT116	viability after 9 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.4561056580925026	[1294]	[384,146]	-3	hSpCas9	negative selection	1991853
37965939	37965962	8	-	26627737	HCT116	viability after 9 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.37611466248449	[957]	[281,129]	-3	hSpCas9	negative selection	1991854
37965264	37965287	8	-	26627737	HCT116	viability after 12 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	1.9131465503365126	[40]	[46,144,55]	9	hSpCas9	negative selection	2074166
37965377	37965400	8	+	26627737	HCT116	viability after 12 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.42461800045492476	[302]	[162,76,110]	-4	hSpCas9	negative selection	2074167
37965802	37965825	8	+	26627737	HCT116	viability after 12 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.34761123834969143	[442]	[309,357,220]	3	hSpCas9	negative selection	2074168
37965939	37965962	8	-	26627737	HCT116	viability after 12 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.006990404839107289	[468]	[295,174,265]	0	hSpCas9	negative selection	2074169
37965264	37965287	8	-	26627737	HCT116	viability after 15 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	1.9011213741668653	[40]	[90,150,22]	9	hSpCas9	negative selection	2156481
37965377	37965400	8	+	26627737	HCT116	viability after 15 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.04603019065813208	[302]	[212,148,180]	0	hSpCas9	negative selection	2156482
37965802	37965825	8	+	26627737	HCT116	viability after 15 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.1879389992460494	[442]	[338,294,241]	2	hSpCas9	negative selection	2156483
37965939	37965962	8	-	26627737	HCT116	viability after 15 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.05226519819563713	[468]	[325,172,287]	0	hSpCas9	negative selection	2156484
37965264	37965287	8	-	26627737	HCT116	viability after 18 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	1.7360625272902979	[40]	[76,87,29]	9	hSpCas9	negative selection	2238796
37965377	37965400	8	+	26627737	HCT116	viability after 18 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.20686887627134629	[302]	[154,150,203]	1	hSpCas9	negative selection	2238797
37965802	37965825	8	+	26627737	HCT116	viability after 18 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.408510957133724	[442]	[259,206,395]	3	hSpCas9	negative selection	2238798
37965939	37965962	8	-	26627737	HCT116	viability after 18 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.30008102609365367	[468]	[155,156,243]	-3	hSpCas9	negative selection	2238799
37966296	37966319	8	+	24336569	HL60	viability	GACCAGCAGGTTGCCTCCCACGG	ADRB3	ENSG00000188778	-1.1238744161085	[862]	[837]	-8	hSpCas9	negative selection	2246842
37966309	37966332	8	-	24336569	HL60	viability	GCGGTGCTGGCCACCGTGGGAGG	ADRB3	ENSG00000188778	1.26837513274217	[214]	[1095]	8	hSpCas9	negative selection	2246843
37966322	37966345	8	-	24336569	HL60	viability	CCTGCTGGCGCTGGCGGTGCTGG	ADRB3	ENSG00000188778	-7.696173944744105	[97]	[0]	-9	hSpCas9	negative selection	2246844
37966347	37966370	8	-	24336569	HL60	viability	CGTGGGAGGCGGCCCTAGCCGGG	ADRB3	ENSG00000188778	0.13251608089135147	[171]	[398]	1	hSpCas9	negative selection	2246845
37966374	37966397	8	-	24336569	HL60	viability	CCAACACCAGTGGGCTGCCAGGG	ADRB3	ENSG00000188778	0.9677794183909529	[827]	[3426]	7	hSpCas9	negative selection	2246846
37966383	37966406	8	+	24336569	HL60	viability	CCCACTGGTGTTGGCGGTATTGG	ADRB3	ENSG00000188778	0.7587554553343345	[123]	[443]	6	hSpCas9	negative selection	2246847
37966391	37966414	8	+	24336569	HL60	viability	TGTTGGCGGTATTGGGCGCCAGG	ADRB3	ENSG00000188778	0.771254402729705	[321]	[1162]	6	hSpCas9	negative selection	2246848
37966396	37966419	8	+	24336569	HL60	viability	GCGGTATTGGGCGCCAGGGTGGG	ADRB3	ENSG00000188778	0.3463150675415296	[309]	[833]	3	hSpCas9	negative selection	2246849
37966435	37966458	8	+	24336569	HL60	viability	GCAAGAGAGCTGTTCTCGTGAGG	ADRB3	ENSG00000188778	0.43910781282230504	[839]	[2409]	4	hSpCas9	negative selection	2246850
37966441	37966464	8	+	24336569	HL60	viability	GAGCTGTTCTCGTGAGGCCACGG	ADRB3	ENSG00000188778	-0.5345288214946942	[1511]	[2208]	-5	hSpCas9	negative selection	2246851
37966296	37966319	8	+	24336569	KBM7	viability	GACCAGCAGGTTGCCTCCCACGG	ADRB3	ENSG00000188778	-0.449397337987862	[396]	[792]	-4	hSpCas9	negative selection	2314019
37966309	37966332	8	-	24336569	KBM7	viability	GCGGTGCTGGCCACCGTGGGAGG	ADRB3	ENSG00000188778	1.033953714516868	[158]	[887]	8	hSpCas9	negative selection	2314020
37966322	37966345	8	-	24336569	KBM7	viability	CCTGCTGGCGCTGGCGGTGCTGG	ADRB3	ENSG00000188778	6.477233307056899	[0]	[242]	9	hSpCas9	negative selection	2314021
37966347	37966370	8	-	24336569	KBM7	viability	CGTGGGAGGCGGCCCTAGCCGGG	ADRB3	ENSG00000188778	1.0605677071214425	[134]	[767]	8	hSpCas9	negative selection	2314022
37966374	37966397	8	-	24336569	KBM7	viability	CCAACACCAGTGGGCTGCCAGGG	ADRB3	ENSG00000188778	0.46761509667542733	[1050]	[3963]	4	hSpCas9	negative selection	2314023
37966383	37966406	8	+	24336569	KBM7	viability	CCCACTGGTGTTGGCGGTATTGG	ADRB3	ENSG00000188778	-0.043188941469547215	[135]	[359]	0	hSpCas9	negative selection	2314024
37966391	37966414	8	+	24336569	KBM7	viability	TGTTGGCGGTATTGGGCGCCAGG	ADRB3	ENSG00000188778	1.1116202081071922	[225]	[1331]	8	hSpCas9	negative selection	2314025
37966396	37966419	8	+	24336569	KBM7	viability	GCGGTATTGGGCGCCAGGGTGGG	ADRB3	ENSG00000188778	0.33862991663717257	[215]	[744]	3	hSpCas9	negative selection	2314026
37966435	37966458	8	+	24336569	KBM7	viability	GCAAGAGAGCTGTTCTCGTGAGG	ADRB3	ENSG00000188778	0.05554045931107732	[821]	[2329]	0	hSpCas9	negative selection	2314027
37966441	37966464	8	+	24336569	KBM7	viability	GAGCTGTTCTCGTGAGGCCACGG	ADRB3	ENSG00000188778	0.4223602628867445	[550]	[2013]	4	hSpCas9	negative selection	2314028
37966753	37966776	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGTTTCCTTTAGCTAAATCTGG	ADRB3	ENSG00000188778	1.2900930599886244	[228,41]	[127,11]	5	dCas9-VP64	positive selection	2383062
37966787	37966810	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGATGGTGGCAGAGGAACCACGG	ADRB3	ENSG00000188778	0.1486039190557602	[55,10]	[7,6]	0	dCas9-VP64	positive selection	2383063
37966834	37966857	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGTGCTATGCTGAGTCCAGG	ADRB3	ENSG00000188778	1.9326992141966912	[291,47]	[261,10]	6	dCas9-VP64	positive selection	2383064
37966753	37966776	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGTTTCCTTTAGCTAAATCTGG	ADRB3	ENSG00000188778	1.5687834670981147	[44,152]	[25,158]	8	dCas9-VP64	positive selection	2478317
37966787	37966810	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGATGGTGGCAGAGGAACCACGG	ADRB3	ENSG00000188778	0.9244100996848537	[19,32]	[10,20]	6	dCas9-VP64	positive selection	2478318
37966834	37966857	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGTGCTATGCTGAGTCCAGG	ADRB3	ENSG00000188778	-0.0981349978315893	[26,23]	[8,5]	-1	dCas9-VP64	positive selection	2478319
37966428	37966451	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAACAGCTCTCTTGCCCCATGG	ADRB3	ENSG00000188778	0.20631560240032276	[6,5]	[6,5]	4	hSpCas9	positive selection	2969223
37966383	37966406	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAATACCGCCAACACCAGTGGG	ADRB3	ENSG00000188778	0.08798955120806287	[3,4]	[3,3]	1	hSpCas9	positive selection	2969224
37965952	37965975	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	-0.20837613691904394	[3,3]	[2,2]	-3	hSpCas9	positive selection	2969225
37965968	37965991	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	-0.31954895165921005	[3,3]	[4,0]	-4	hSpCas9	positive selection	2969226
37966428	37966451	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAACAGCTCTCTTGCCCCATGG	ADRB3	ENSG00000188778	0.10688735479406286	[6,6]	[5,3]	2	hSpCas9	positive selection	3037081
37966383	37966406	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAATACCGCCAACACCAGTGGG	ADRB3	ENSG00000188778	-0.5914009961358373	[3,3]	[3,0]	-7	hSpCas9	positive selection	3037082
37965952	37965975	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	-0.06274977972363685	[3,3]	[2,2]	-1	hSpCas9	positive selection	3037083
37965968	37965991	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	-0.049632177005557485	[3,3]	[3,1]	0	hSpCas9	positive selection	3037084
37965257	37965280		+	24336571	A375	resistance to PLX after 7 days	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.029207105042075576	[15,18]	[16,18]	1	hSpCas9	positive selection	3107377
37964229	37964252		-	24336571	A375	resistance to PLX after 7 days	TTTTTTTCCCAGGGCTTCTTGGG	ADRB3	ENSG00000188778	0.23483305976965752	[6,5]	[8,6]	7	hSpCas9	positive selection	3107388
37965257	37965280		+	24336571	A375	resistance to PLX after 14 days	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.27904869156933976	[11,14]	[4,4]	-3	hSpCas9	positive selection	3165170
37964229	37964252		-	24336571	A375	resistance to PLX after 14 days	TTTTTTTCCCAGGGCTTCTTGGG	ADRB3	ENSG00000188778	0.3030141119091353	[4,5]	[2,2]	3	hSpCas9	positive selection	3165181
37965257	37965280		+	24336571	A375	viability after 7 days	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.11065048380510067	[16]	[15,18]	1	hSpCas9	negative selection	3222963
37964229	37964252		-	24336571	A375	viability after 7 days	TTTTTTTCCCAGGGCTTCTTGGG	ADRB3	ENSG00000188778	-0.49060529714155576	[10]	[6,5]	-6	hSpCas9	negative selection	3222974
37965257	37965280		+	24336571	A375	viability after 14 days	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.24737898412829532	[16]	[11,14]	-3	hSpCas9	negative selection	3280756
37964229	37964252		-	24336571	A375	viability after 14 days	TTTTTTTCCCAGGGCTTCTTGGG	ADRB3	ENSG00000188778	-0.6981965551070181	[10]	[4,5]	-7	hSpCas9	negative selection	3280767
37965257	37965280	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.28459351816978484	[173,202]	[0,1]	1	hSpCas9	positive selection	3335800
37966033	37966056	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	2.2567369955745087	[33,29]	[0,0]	8	hSpCas9	positive selection	3335801
37966232	37966255	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.5842539002917605	[108,94]	[0,0]	3	hSpCas9	positive selection	3335802
37965923	37965946	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	-1.5075453792902558	[434,434]	[0,0]	-8	hSpCas9	positive selection	3355049
37965792	37965815	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	1.107579091941153	[70,70]	[0,0]	5	hSpCas9	positive selection	3355050
37966233	37966256	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.5435736884744696	[222,222]	[0,0]	-4	hSpCas9	positive selection	3355051
37966428	37966451	8	-	26780180	HT29	viability (Avana library 4 designs)	AGAACAGCTCTCTTGCCCCATGG	ADRB3	ENSG00000188778	-0.278440976571613	[]	[]	-4	hSpCas9	negative selection	3405289
37966383	37966406	8	-	26780180	HT29	viability (Avana library 4 designs)	CCAATACCGCCAACACCAGTGGG	ADRB3	ENSG00000188778	0.613297742870081	[]	[]	2	hSpCas9	negative selection	3405290
37965951	37965974	8	+	26780180	HT29	viability (Avana library 4 designs)	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	1.22583666344704	[]	[]	5	hSpCas9	negative selection	3405291
37965968	37965991	8	-	26780180	HT29	viability (Avana library 4 designs)	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.754599071016539	[]	[]	3	hSpCas9	negative selection	3405292
37965951	37965974	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	5.07065713111028	[]	[]	8	hSpCas9	negative selection	3477226
37966383	37966406	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAATACCGCCAACACCAGTGGG	ADRB3	ENSG00000188778	-0.592520415490892	[]	[]	0	hSpCas9	negative selection	3477227
37966428	37966451	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAACAGCTCTCTTGCCCCATGG	ADRB3	ENSG00000188778	3.51154467946423	[]	[]	5	hSpCas9	negative selection	3477228
37965968	37965991	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	5.36379677929184	[]	[]	8	hSpCas9	negative selection	3477229
37966046	37966069	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTGGTCACAGCCAGGTAGCGG	ADRB3	ENSG00000188778	4.67645111385191	[]	[]	7	hSpCas9	negative selection	3477230
37966138	37966161	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCGCAGCCAGTGGCGCCCAACGG	ADRB3	ENSG00000188778	5.00058705663859	[]	[]	8	hSpCas9	negative selection	3477231
37965951	37965974	8	+	26780180	A375	viability (Avana lentiGuide)	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	-0.660089188676857	[]	[]	-1	hSpCas9	negative selection	3585885
37966383	37966406	8	-	26780180	A375	viability (Avana lentiGuide)	CCAATACCGCCAACACCAGTGGG	ADRB3	ENSG00000188778	-1.85673924227555	[]	[]	-3	hSpCas9	negative selection	3585886
37966428	37966451	8	-	26780180	A375	viability (Avana lentiGuide)	AGAACAGCTCTCTTGCCCCATGG	ADRB3	ENSG00000188778	-1.95087120177133	[]	[]	-3	hSpCas9	negative selection	3585887
37965968	37965991	8	-	26780180	A375	viability (Avana lentiGuide)	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	2.52846955043404	[]	[]	2	hSpCas9	negative selection	3585888
37966046	37966069	8	+	26780180	A375	viability (Avana lentiGuide)	GGTTGGTCACAGCCAGGTAGCGG	ADRB3	ENSG00000188778	-1.61537510051278	[]	[]	-3	hSpCas9	negative selection	3585889
37966138	37966161	8	+	26780180	A375	viability (Avana lentiGuide)	TCGCAGCCAGTGGCGCCCAACGG	ADRB3	ENSG00000188778	-7.3834456130426	[]	[]	-9	hSpCas9	negative selection	3585890
37965951	37965974	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.2635135743413827	[5]	[6,6]	7	hSpCas9	positive selection	3694544
37966383	37966406	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAATACCGCCAACACCAGTGGG	ADRB3	ENSG00000188778	-0.06972971379505152	[4]	[5,2]	-1	hSpCas9	positive selection	3694545
37966428	37966451	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAACAGCTCTCTTGCCCCATGG	ADRB3	ENSG00000188778	0.280411958910983	[6]	[7,8]	7	hSpCas9	positive selection	3694546
37965968	37965991	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.2935839078430278	[5]	[6,6]	8	hSpCas9	positive selection	3694547
37966046	37966069	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTGGTCACAGCCAGGTAGCGG	ADRB3	ENSG00000188778	0.3137253101855011	[4]	[5,5]	8	hSpCas9	positive selection	3694548
37966138	37966161	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCGCAGCCAGTGGCGCCCAACGG	ADRB3	ENSG00000188778	0.22924438297667932	[4]	[5,4]	6	hSpCas9	positive selection	3694549
37965951	37965974	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.27648814643496145	[5]	[6,5]	7	hSpCas9	positive selection	3803151
37966383	37966406	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAATACCGCCAACACCAGTGGG	ADRB3	ENSG00000188778	-0.204132580271327	[5]	[2,4]	-3	hSpCas9	positive selection	3803152
37966428	37966451	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAACAGCTCTCTTGCCCCATGG	ADRB3	ENSG00000188778	0.1950815304664092	[7]	[7,7]	5	hSpCas9	positive selection	3803153
37965968	37965991	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.12823337010640667	[5]	[4,5]	3	hSpCas9	positive selection	3803154
37966046	37966069	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTGGTCACAGCCAGGTAGCGG	ADRB3	ENSG00000188778	0.24288964478723982	[5]	[3,6]	6	hSpCas9	positive selection	3803155
37966138	37966161	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCGCAGCCAGTGGCGCCCAACGG	ADRB3	ENSG00000188778	0.20996849423361585	[4]	[3,4]	5	hSpCas9	positive selection	3803156
37966232	37966255	8	-	26780180	A375	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	1.09378879344042	[]	[]	5	hSpCas9	negative selection	3911616
37966233	37966256	8	+	26780180	A375	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	0.521938457182162	[]	[]	1	hSpCas9	negative selection	3911617
37965923	37965946	8	+	26780180	A375	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.63411318770275	[]	[]	2	hSpCas9	negative selection	3911618
37966033	37966056	8	-	26780180	A375	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.6035467908028	[]	[]	2	hSpCas9	negative selection	3911619
37965792	37965815	8	-	26780180	A375	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.893461542446341	[]	[]	4	hSpCas9	negative selection	3911620
37965257	37965280	8	+	26780180	A375	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	1.13027959302077	[]	[]	5	hSpCas9	negative selection	3911621
37966232	37966255	8	-	26780180	HT29	viability (GeCKOv2 library)	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	1.76295719256362	[]	[]	8	hSpCas9	negative selection	4019582
37966233	37966256	8	+	26780180	HT29	viability (GeCKOv2 library)	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	0.697384174021954	[]	[]	2	hSpCas9	negative selection	4019583
37965923	37965946	8	+	26780180	HT29	viability (GeCKOv2 library)	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.227538312114032	[]	[]	0	hSpCas9	negative selection	4019584
37966033	37966056	8	-	26780180	HT29	viability (GeCKOv2 library)	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.940124070737207	[]	[]	4	hSpCas9	negative selection	4019585
37965792	37965815	8	-	26780180	HT29	viability (GeCKOv2 library)	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	1.62025987716561	[]	[]	8	hSpCas9	negative selection	4019586
37965257	37965280	8	+	26780180	HT29	viability (GeCKOv2 library)	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.827651544688799	[]	[]	3	hSpCas9	negative selection	4019587
37965257	37965280	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.09396503960135122	[3]	[2,2]	-2	hSpCas9	positive selection	4129633
37964229	37964252	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTTTTTCCCAGGGCTTCTTGGG	ADRB3	ENSG00000188778	-0.012132453759733652	[2]	[2,1]	0	hSpCas9	positive selection	4129644
37965257	37965280	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.5953399720651069	[4]	[2,1,1,2]	4	hSpCas9	positive selection	4193655
37964229	37964252	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTTTTTCCCAGGGCTTCTTGGG	ADRB3	ENSG00000188778	0.10840146463677058	[2]	[1,1,0,0]	0	hSpCas9	positive selection	4193666
37965257	37965280	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.3193569096159288	[4]	[4,3]	6	hSpCas9	positive selection	4254764
37966033	37966056	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.08466597219144079	[1]	[1,0]	-2	hSpCas9	positive selection	4254765
37966232	37966255	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.35718961422262857	[3]	[3,2]	7	hSpCas9	positive selection	4254766
37965923	37965946	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.25703088022624465	[3]	[4,3]	5	hSpCas9	positive selection	4319046
37965792	37965815	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.047948528336045015	[1]	[1,1]	1	hSpCas9	positive selection	4319047
37966233	37966256	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	0.4908247253987863	[3]	[4,4]	8	hSpCas9	positive selection	4319048
37965924	37965946	8	+	27760321	OCIAML3	viability	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.5983281526969375	[913,732]	[853,1119]	7	hSpCas9	negative selection	4376546
37965952	37965974	8	+	27760321	OCIAML3	viability	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.4197140196040491	[529,422]	[452,550]	5	hSpCas9	negative selection	4376547
37966026	37966048	8	+	27760321	OCIAML3	viability	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-1.3447352105409547	[496,451]	[132,162]	-8	hSpCas9	negative selection	4376548
37966076	37966098	8	-	27760321	OCIAML3	viability	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.3265946560066184	[942,770]	[706,1004]	4	hSpCas9	negative selection	4376549
37966234	37966256	8	+	27760321	OCIAML3	viability	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.431429066973119	[465,390]	[227,272]	-4	hSpCas9	negative selection	4376550
37965924	37965946	8	+	27760321	OCIAML2	viability	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.2665231658547116	[913,732]	[769,831]	3	hSpCas9	negative selection	4460009
37965952	37965974	8	+	27760321	OCIAML2	viability	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.12241191774582914	[529,422]	[420,411]	1	hSpCas9	negative selection	4460010
37966026	37966048	8	+	27760321	OCIAML2	viability	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.8443882941941663	[496,451]	[242,174]	-7	hSpCas9	negative selection	4460011
37966076	37966098	8	-	27760321	OCIAML2	viability	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.4008853425431509	[942,770]	[770,1094]	5	hSpCas9	negative selection	4460012
37966234	37966256	8	+	27760321	OCIAML2	viability	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-1.1778758122663064	[465,390]	[124,188]	-8	hSpCas9	negative selection	4460013
37965924	37965946	8	+	27760321	MV411	viability	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	1.1162944649799735	[913,732]	[1576,561]	7	hSpCas9	negative selection	4543472
37965952	37965974	8	+	27760321	MV411	viability	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	-0.40096270077523777	[529,422]	[153,360]	-3	hSpCas9	negative selection	4543473
37966026	37966048	8	+	27760321	MV411	viability	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	0.03512589323193707	[496,451]	[374,238]	0	hSpCas9	negative selection	4543474
37966076	37966098	8	-	27760321	MV411	viability	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	1.0173839528403816	[942,770]	[1272,937]	7	hSpCas9	negative selection	4543475
37966234	37966256	8	+	27760321	MV411	viability	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-1.5535461806702713	[465,390]	[41,176]	-7	hSpCas9	negative selection	4543476
37965924	37965946	8	+	27760321	HL60	viability	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	-0.16760367505971385	[913,732]	[627,560]	-2	hSpCas9	negative selection	4626935
37965952	37965974	8	+	27760321	HL60	viability	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.5630553781395424	[529,422]	[526,618]	6	hSpCas9	negative selection	4626936
37966026	37966048	8	+	27760321	HL60	viability	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.474105761370223	[496,451]	[224,335]	-5	hSpCas9	negative selection	4626937
37966076	37966098	8	-	27760321	HL60	viability	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.2289046007691864	[942,770]	[662,978]	3	hSpCas9	negative selection	4626938
37966234	37966256	8	+	27760321	HL60	viability	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.7186967725245481	[465,390]	[223,198]	-6	hSpCas9	negative selection	4626939
37965924	37965946	8	+	27760321	HT1080	viability	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.4815164659900659	[732,571]	[413,306]	2	hSpCas9	negative selection	4710398
37965952	37965974	8	+	27760321	HT1080	viability	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.41648527071449887	[422,329]	[87,322]	2	hSpCas9	negative selection	4710399
37966026	37966048	8	+	27760321	HT1080	viability	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.8491269046716713	[451,352]	[141,30]	-4	hSpCas9	negative selection	4710400
37966076	37966098	8	-	27760321	HT1080	viability	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.7425702701881353	[770,601]	[332,593]	4	hSpCas9	negative selection	4710401
37966234	37966256	8	+	27760321	HT1080	viability	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.11343076651967665	[390,304]	[204,43]	0	hSpCas9	negative selection	4710402
37965924	37965946	8	+	27760321	HT29	viability after 7 days	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.3880181831862908	[732,571]	[1181,1092,1030]	6	hSpCas9	negative selection	4793861
37965952	37965974	8	+	27760321	HT29	viability after 7 days	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.08898369878182204	[422,329]	[740,508,331]	1	hSpCas9	negative selection	4793862
37966026	37966048	8	+	27760321	HT29	viability after 7 days	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.5158460860612502	[451,352]	[395,326,366]	-6	hSpCas9	negative selection	4793863
37966076	37966098	8	-	27760321	HT29	viability after 7 days	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	-0.03696637496990307	[770,601]	[1269,565,803]	0	hSpCas9	negative selection	4793864
37966234	37966256	8	+	27760321	HT29	viability after 7 days	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.49480299446888976	[390,304]	[516,224,240]	-6	hSpCas9	negative selection	4793865
37965924	37965946	8	+	27760321	HT29	viability after 25 days	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.5400078442724761	[732,571]	[866,1146,1269]	6	hSpCas9	negative selection	4877324
37965952	37965974	8	+	27760321	HT29	viability after 25 days	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.6405131433631899	[422,329]	[510,582,956]	7	hSpCas9	negative selection	4877325
37966026	37966048	8	+	27760321	HT29	viability after 25 days	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.2614237939808775	[451,352]	[314,404,440]	-3	hSpCas9	negative selection	4877326
37966076	37966098	8	-	27760321	HT29	viability after 25 days	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.5120573782821191	[770,601]	[1112,1004,1250]	5	hSpCas9	negative selection	4877327
37966234	37966256	8	+	27760321	HT29	viability after 25 days	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	0.020680519282403054	[390,304]	[358,548,292]	0	hSpCas9	negative selection	4877328
37965924	37965946	8	+	27760321	HT29	viability after 22 days	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.6917528179575989	[732,571]	[1196,1108,1350]	7	hSpCas9	negative selection	4960787
37965952	37965974	8	+	27760321	HT29	viability after 22 days	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.45616246466120447	[422,329]	[555,575,660]	5	hSpCas9	negative selection	4960788
37966026	37966048	8	+	27760321	HT29	viability after 22 days	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.014534238353009682	[451,352]	[452,382,546]	0	hSpCas9	negative selection	4960789
37966076	37966098	8	-	27760321	HT29	viability after 22 days	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.682321082970638	[770,601]	[1375,1265,1174]	7	hSpCas9	negative selection	4960790
37966234	37966256	8	+	27760321	HT29	viability after 22 days	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.44337405985348766	[390,304]	[408,229,244]	-4	hSpCas9	negative selection	4960791
37965924	37965946	8	+	27760321	HT29	viability after 19 days	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.9885043713919579	[732,571]	[1189,1431,1776]	8	hSpCas9	negative selection	5044250
37965952	37965974	8	+	27760321	HT29	viability after 19 days	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.6553707895277503	[422,329]	[517,678,814]	6	hSpCas9	negative selection	5044251
37966026	37966048	8	+	27760321	HT29	viability after 19 days	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.26902801430043793	[451,352]	[387,363,393]	-3	hSpCas9	negative selection	5044252
37966076	37966098	8	-	27760321	HT29	viability after 19 days	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.6480009033582873	[770,601]	[1264,1605,837]	6	hSpCas9	negative selection	5044253
37966234	37966256	8	+	27760321	HT29	viability after 19 days	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.06919539825564074	[390,304]	[367,667,110]	0	hSpCas9	negative selection	5044254
37965924	37965946	8	+	27760321	HT29	viability after 16 days	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.5324905258564225	[732,571]	[893,1065,1191]	6	hSpCas9	negative selection	5127713
37965952	37965974	8	+	27760321	HT29	viability after 16 days	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.2930251083748916	[422,329]	[560,339,655]	3	hSpCas9	negative selection	5127714
37966026	37966048	8	+	27760321	HT29	viability after 16 days	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.14450838535826888	[451,352]	[399,463,355]	-1	hSpCas9	negative selection	5127715
37966076	37966098	8	-	27760321	HT29	viability after 16 days	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.5271982018208562	[770,601]	[1328,819,1199]	6	hSpCas9	negative selection	5127716
37966234	37966256	8	+	27760321	HT29	viability after 16 days	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.45222506170547494	[390,304]	[375,180,307]	-4	hSpCas9	negative selection	5127717
37965924	37965946	8	+	27760321	HT29	viability after 13 days	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.43964598082538253	[732,571]	[1126,831,1114]	5	hSpCas9	negative selection	5211176
37965952	37965974	8	+	27760321	HT29	viability after 13 days	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.08532717726426454	[422,329]	[463,546,383]	1	hSpCas9	negative selection	5211177
37966026	37966048	8	+	27760321	HT29	viability after 13 days	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.1664402877065695	[451,352]	[586,350,315]	-2	hSpCas9	negative selection	5211178
37966076	37966098	8	-	27760321	HT29	viability after 13 days	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.18781109842297738	[770,601]	[934,1010,782]	2	hSpCas9	negative selection	5211179
37966234	37966256	8	+	27760321	HT29	viability after 13 days	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.051010158731393015	[390,304]	[605,147,412]	0	hSpCas9	negative selection	5211180
37965924	37965946	8	+	27760321	HT29	viability after 10 days	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.6215264081467358	[732,571]	[1105,999,1637]	8	hSpCas9	negative selection	5294639
37965952	37965974	8	+	27760321	HT29	viability after 10 days	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.09446887812514941	[422,329]	[400,595,510]	1	hSpCas9	negative selection	5294640
37966026	37966048	8	+	27760321	HT29	viability after 10 days	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-0.6602245556091686	[451,352]	[461,293,199]	-6	hSpCas9	negative selection	5294641
37966076	37966098	8	-	27760321	HT29	viability after 10 days	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	-0.058250804988817406	[770,601]	[578,920,968]	-1	hSpCas9	negative selection	5294642
37966234	37966256	8	+	27760321	HT29	viability after 10 days	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	0.15204100033246992	[390,304]	[324,708,421]	2	hSpCas9	negative selection	5294643
37965924	37965946	8	+	27760321	MOLM13	viability	GGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	1.446308102507711	[913,732]	[1475,1073]	8	hSpCas9	negative selection	5378102
37965952	37965974	8	+	27760321	MOLM13	viability	ATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	1.0550982553536106	[529,422]	[436,655]	7	hSpCas9	negative selection	5378103
37966026	37966048	8	+	27760321	MOLM13	viability	CAGTGCGCCGTAACGCAGCGGG	ADRB3	ENSG00000188778	-1.628486893959773	[496,451]	[112,63]	-7	hSpCas9	negative selection	5378104
37966076	37966098	8	-	27760321	MOLM13	viability	ATCGAAACCCTGTGCGCCCTGG	ADRB3	ENSG00000188778	0.39274929105999346	[942,770]	[299,913]	2	hSpCas9	negative selection	5378105
37966234	37966256	8	+	27760321	MOLM13	viability	AGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.001970051002530185	[465,390]	[354,142]	0	hSpCas9	negative selection	5378106
37965459	37965482	8	+	27661255	K562	viability	GGCATAACCTAGCCAGTTCAGGG	ADRB3	ENSG00000188778	0.32794174823057365	[532,497]	[530,505]	9	dCas9-KRAB	negative selection	5461198
37965841	37965864	8	+	27661255	K562	viability	GAGGAGGACAGCAGCACGTAGGG	ADRB3	ENSG00000188778	0.1582937105442468	[1133,1176]	[1125,946]	5	dCas9-KRAB	negative selection	5461199
37966128	37966151	8	+	27661255	K562	viability	GGTCCACAGCTCGCAGCCAGTGG	ADRB3	ENSG00000188778	0.25882664572131947	[907,1087]	[1014,895]	8	dCas9-KRAB	negative selection	5461200
37965251	37965274	8	-	27661255	K562	viability	GCTCGACGGGTAGGTAACCGGGG	ADRB3	ENSG00000188778	0.0877937361296679	[61,75]	[66,50]	3	dCas9-KRAB	negative selection	5461201
37966210	37966233	8	-	27661255	K562	viability	GCCGCAGCCGACCTGGTGATGGG	ADRB3	ENSG00000188778	0.4253601892903265	[209,183]	[274,157]	9	dCas9-KRAB	negative selection	5461202
37965257	37965280	8	+	27260156	BXPC3	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.0820136695621132	[1123]	[978,1131,1155,1189]	-2	hSpCas9	negative selection	5527224
37966033	37966056	8	-	27260156	BXPC3	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.22404837011710743	[110]	[153,98,150,137]	5	hSpCas9	negative selection	5527225
37966232	37966255	8	-	27260156	BXPC3	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.24799984941535108	[491]	[334,465,527,407]	-5	hSpCas9	negative selection	5527226
37965923	37965946	8	+	27260156	BXPC3	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.32403960835855294	[920]	[989,1136,1477,1245]	7	hSpCas9	negative selection	5591506
37965792	37965815	8	-	27260156	BXPC3	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.1508144701780041	[196]	[169,135,219,224]	-3	hSpCas9	negative selection	5591507
37966233	37966256	8	+	27260156	BXPC3	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.17476063896989102	[908]	[711,734,951,1005]	-4	hSpCas9	negative selection	5591508
37965257	37965280	8	+	27260156	A673	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.152888355873243	[1123]	[1338,1349,924,1254]	-4	hSpCas9	negative selection	5648475
37966033	37966056	8	-	27260156	A673	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.2079241479905516	[110]	[191,124,202,96]	5	hSpCas9	negative selection	5648476
37966232	37966255	8	-	27260156	A673	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.1286871095836713	[491]	[605,587,514,452]	-3	hSpCas9	negative selection	5648477
37965923	37965946	8	+	27260156	A673	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.2134786409512487	[920]	[1510,1184,1181,1277]	5	hSpCas9	negative selection	5712757
37965792	37965815	8	-	27260156	A673	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.24462376315931622	[196]	[201,212,172,210]	-6	hSpCas9	negative selection	5712758
37966233	37966256	8	+	27260156	A673	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.351088002059861	[908]	[981,780,905,762]	-7	hSpCas9	negative selection	5712759
37965257	37965280	8	+	27260156	A375	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.0264854287750389	[1123]	[1035,1540,1521,1106]	0	hSpCas9	negative selection	5769726
37966033	37966056	8	-	27260156	A375	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.0932530951061663	[110]	[183,121,93,89]	-1	hSpCas9	negative selection	5769727
37966232	37966255	8	-	27260156	A375	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.3852224636993189	[491]	[696,877,870,589]	5	hSpCas9	negative selection	5769728
37965923	37965946	8	+	27260156	A375	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.24687567558808843	[920]	[1159,1655,1384,986]	3	hSpCas9	negative selection	5834008
37965792	37965815	8	-	27260156	A375	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.10076009216913695	[196]	[288,261,232,208]	1	hSpCas9	negative selection	5834009
37966233	37966256	8	+	27260156	A375	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.09562332977450316	[908]	[990,1092,1004,905]	-1	hSpCas9	negative selection	5834010
37965257	37965280	8	+	27260156	COLO741	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.2775735584374345	[1123]	[1356,1038,1170]	-5	hSpCas9	negative selection	5890977
37966033	37966056	8	-	27260156	COLO741	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.5961241334174399	[110]	[317,170,165]	9	hSpCas9	negative selection	5890978
37966232	37966255	8	-	27260156	COLO741	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.10091615942049262	[491]	[690,748,588]	2	hSpCas9	negative selection	5890979
37965923	37965946	8	+	27260156	COLO741	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.27014955757772474	[920]	[1492,1525,1253]	5	hSpCas9	negative selection	5955259
37965792	37965815	8	-	27260156	COLO741	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.3968881359388108	[196]	[283,94,200]	-7	hSpCas9	negative selection	5955260
37966233	37966256	8	+	27260156	COLO741	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.23562321241980033	[908]	[1045,859,1050]	-5	hSpCas9	negative selection	5955261
37965257	37965280	8	+	27260156	CAL120	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.7552230063288065	[1123]	[852,678,954]	-8	hSpCas9	negative selection	6012228
37966033	37966056	8	-	27260156	CAL120	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.2653014941197549	[110]	[101,137,102]	-4	hSpCas9	negative selection	6012229
37966232	37966255	8	-	27260156	CAL120	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.288505614933283	[491]	[537,294,672]	-4	hSpCas9	negative selection	6012230
37965923	37965946	8	+	27260156	CAL120	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	-0.2720052375743025	[920]	[1057,1167,642]	-4	hSpCas9	negative selection	6076510
37965792	37965815	8	-	27260156	CAL120	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.017107405370632822	[196]	[265,187,291]	0	hSpCas9	negative selection	6076511
37966233	37966256	8	+	27260156	CAL120	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-1.0345488544635464	[908]	[702,421,553]	-8	hSpCas9	negative selection	6076512
37965257	37965280	8	+	27260156	CADOES1	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.6593692584357668	[1123]	[639,677,556,776]	-8	hSpCas9	negative selection	6133479
37966033	37966056	8	-	27260156	CADOES1	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.717368880836617	[110]	[51,29,108,59]	-8	hSpCas9	negative selection	6133480
37966232	37966255	8	-	27260156	CADOES1	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.03658445536095324	[491]	[444,323,538,572]	0	hSpCas9	negative selection	6133481
37965923	37965946	8	+	27260156	CADOES1	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	-0.04391057425803946	[920]	[642,801,843,1042]	0	hSpCas9	negative selection	6197761
37965792	37965815	8	-	27260156	CADOES1	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.14489128411794217	[196]	[95,269,132,315]	2	hSpCas9	negative selection	6197762
37966233	37966256	8	+	27260156	CADOES1	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.7697202602505554	[908]	[508,442,517,513]	-8	hSpCas9	negative selection	6197763
37965257	37965280	8	+	27260156	EWS502	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.1288885190911322	[1123]	[1070,1082,990,1215]	-2	hSpCas9	negative selection	6254730
37966033	37966056	8	-	27260156	EWS502	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.3266646275951366	[110]	[128,107,191,165]	6	hSpCas9	negative selection	6254731
37966232	37966255	8	-	27260156	EWS502	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.22421736913797022	[491]	[511,735,513,680]	4	hSpCas9	negative selection	6254732
37965923	37965946	8	+	27260156	EWS502	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.29274439714477907	[920]	[1238,1204,1105,1219]	5	hSpCas9	negative selection	6319012
37965792	37965815	8	-	27260156	EWS502	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.3596308432967872	[196]	[189,123,110,226]	-6	hSpCas9	negative selection	6319013
37966233	37966256	8	+	27260156	EWS502	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.40674362409175413	[908]	[670,717,733,790]	-6	hSpCas9	negative selection	6319014
37965257	37965280	8	+	27260156	EW8	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.19658698339881697	[1123]	[664,863,884,733]	-4	hSpCas9	negative selection	6375981
37966033	37966056	8	-	27260156	EW8	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.15666982809748453	[110]	[75,171,79,73]	3	hSpCas9	negative selection	6375982
37966232	37966255	8	-	27260156	EW8	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.1132907720096227	[491]	[489,345,223,450]	-2	hSpCas9	negative selection	6375983
37965923	37965946	8	+	27260156	EW8	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.10736737517509265	[920]	[865,645,735,982]	2	hSpCas9	negative selection	6440263
37965792	37965815	8	-	27260156	EW8	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.014703187356807756	[196]	[230,191,189,34]	0	hSpCas9	negative selection	6440264
37966233	37966256	8	+	27260156	EW8	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.2741829990997706	[908]	[559,455,579,836]	-5	hSpCas9	negative selection	6440265
37965257	37965280	8	+	27260156	CORL105	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.18570904744803496	[1123]	[914,1163,1407,1170]	-3	hSpCas9	negative selection	6497232
37966033	37966056	8	-	27260156	CORL105	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.33788873663382857	[110]	[181,175,117,173]	6	hSpCas9	negative selection	6497233
37966232	37966255	8	-	27260156	CORL105	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.1832054222789321	[491]	[423,506,564,538]	-3	hSpCas9	negative selection	6497234
37965923	37965946	8	+	27260156	CORL105	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.25775312315852295	[920]	[1373,1212,1373,1212]	5	hSpCas9	negative selection	6561514
37965792	37965815	8	-	27260156	CORL105	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.5063469157639675	[196]	[147,188,165,145]	-7	hSpCas9	negative selection	6561515
37966233	37966256	8	+	27260156	CORL105	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.5912375796165932	[908]	[628,675,870,672]	-8	hSpCas9	negative selection	6561516
37965257	37965280	8	+	27260156	HS294T	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.04529512277660519	[1123]	[430,441,473,446]	0	hSpCas9	negative selection	6618483
37966033	37966056	8	-	27260156	HS294T	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.7941931135997595	[110]	[51,27,152,66]	8	hSpCas9	negative selection	6618484
37966232	37966255	8	-	27260156	HS294T	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.19343800164654032	[491]	[159,159,147,203]	-3	hSpCas9	negative selection	6618485
37965923	37965946	8	+	27260156	HS294T	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.3624452852191343	[920]	[419,556,359,499]	5	hSpCas9	negative selection	6682765
37965792	37965815	8	-	27260156	HS294T	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.3757093401524272	[196]	[48,70,50,255]	5	hSpCas9	negative selection	6682766
37966233	37966256	8	+	27260156	HS294T	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	0.19871990305784626	[908]	[526,296,299,494]	2	hSpCas9	negative selection	6682767
37965257	37965280	8	+	27260156	HCC44	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.011609880355184288	[1123]	[1139,983,1793,1236]	0	hSpCas9	negative selection	6739734
37966033	37966056	8	-	27260156	HCC44	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	1.1370821217043086	[110]	[335,79,540,225]	9	hSpCas9	negative selection	6739735
37966232	37966255	8	-	27260156	HCC44	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.29904657861468686	[491]	[689,489,813,785]	5	hSpCas9	negative selection	6739736
37965923	37965946	8	+	27260156	HCC44	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.4964519955032577	[920]	[1460,1104,2092,1368]	7	hSpCas9	negative selection	6804016
37965792	37965815	8	-	27260156	HCC44	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.3341715260860092	[196]	[267,113,255,100]	-5	hSpCas9	negative selection	6804017
37966233	37966256	8	+	27260156	HCC44	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.2886494831708145	[908]	[1138,727,646,854]	-4	hSpCas9	negative selection	6804018
37965257	37965280	8	+	27260156	G402	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.5234962378960334	[1123]	[1540,833,675,844]	-6	hSpCas9	negative selection	6860985
37966033	37966056	8	-	27260156	G402	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.2125406649747923	[110]	[65,84,64,235]	-3	hSpCas9	negative selection	6860986
37966232	37966255	8	-	27260156	G402	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.43607733153153105	[491]	[783,912,1024,538]	5	hSpCas9	negative selection	6860987
37965923	37965946	8	+	27260156	G402	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.29974843959937336	[920]	[1239,1592,1251,1431]	4	hSpCas9	negative selection	6925267
37965792	37965815	8	-	27260156	G402	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.4886443133932774	[196]	[229,205,106,152]	-6	hSpCas9	negative selection	6925268
37966233	37966256	8	+	27260156	G402	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.6283737976332139	[908]	[1068,695,840,329]	-6	hSpCas9	negative selection	6925269
37965257	37965280	8	+	27260156	L33	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.2397609480113616	[1123]	[975,394,572,954]	-5	hSpCas9	negative selection	6982236
37966033	37966056	8	-	27260156	L33	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.14172307263194606	[110]	[87,55,73,147]	3	hSpCas9	negative selection	6982237
37966232	37966255	8	-	27260156	L33	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.21145834126500118	[491]	[456,157,235,479]	-5	hSpCas9	negative selection	6982238
37965923	37965946	8	+	27260156	L33	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.14603301173816663	[920]	[946,425,707,965]	3	hSpCas9	negative selection	7046518
37965792	37965815	8	-	27260156	L33	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.40897781156919577	[196]	[93,78,113,126]	-7	hSpCas9	negative selection	7046519
37966233	37966256	8	+	27260156	L33	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.07305314807944463	[908]	[777,382,552,865]	-2	hSpCas9	negative selection	7046520
37965257	37965280	8	+	27260156	K562	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.3552582276898888	[1123]	[2533,1250,703,770]	4	hSpCas9	negative selection	7103487
37966033	37966056	8	-	27260156	K562	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.31106962404088967	[110]	[200,149,86,64]	4	hSpCas9	negative selection	7103488
37966232	37966255	8	-	27260156	K562	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.36563874187940426	[491]	[385,180,324,444]	-4	hSpCas9	negative selection	7103489
37965923	37965946	8	+	27260156	K562	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.40606041044136487	[920]	[1534,1162,817,876]	5	hSpCas9	negative selection	7167769
37965792	37965815	8	-	27260156	K562	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.18973324981772555	[196]	[276,289,108,138]	2	hSpCas9	negative selection	7167770
37966233	37966256	8	+	27260156	K562	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.1287591564537477	[908]	[1162,596,680,555]	-2	hSpCas9	negative selection	7167771
37965257	37965280	8	+	27260156	HT29	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.2501645629962448	[1123]	[1126,1485,1137,894]	-5	hSpCas9	negative selection	7224738
37966033	37966056	8	-	27260156	HT29	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.0320803168181234	[110]	[132,153,137,106]	0	hSpCas9	negative selection	7224739
37966232	37966255	8	-	27260156	HT29	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.016510991907464488	[491]	[600,834,440,514]	0	hSpCas9	negative selection	7224740
37965923	37965946	8	+	27260156	HT29	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.19791763255905692	[920]	[1284,1382,1219,1251]	4	hSpCas9	negative selection	7289020
37965792	37965815	8	-	27260156	HT29	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.29321975269996825	[196]	[156,193,174,244]	-5	hSpCas9	negative selection	7289021
37966233	37966256	8	+	27260156	HT29	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.3015696078944232	[908]	[772,1076,895,845]	-5	hSpCas9	negative selection	7289022
37965257	37965280	8	+	27260156	MHHES1	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.0650265230588647	[1123]	[1307,1120,1363,1058]	-1	hSpCas9	negative selection	7345989
37966033	37966056	8	-	27260156	MHHES1	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.0046067575182560105	[110]	[249,90,92,82]	0	hSpCas9	negative selection	7345990
37966232	37966255	8	-	27260156	MHHES1	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.013044357231535145	[491]	[526,653,605,464]	0	hSpCas9	negative selection	7345991
37965923	37965946	8	+	27260156	MHHES1	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.21037850087442622	[920]	[1725,1020,1107,1007]	4	hSpCas9	negative selection	7410271
37965792	37965815	8	-	27260156	MHHES1	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.45350732929758353	[196]	[226,264,39,135]	-7	hSpCas9	negative selection	7410272
37966233	37966256	8	+	27260156	MHHES1	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.25689472263212243	[908]	[791,1040,731,852]	-5	hSpCas9	negative selection	7410273
37965257	37965280	8	+	27260156	MEWO	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.07275799188592336	[1123]	[1112,1052,854]	-1	hSpCas9	negative selection	7467240
37966033	37966056	8	-	27260156	MEWO	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.7855724379283766	[110]	[137,187,202]	9	hSpCas9	negative selection	7467241
37966232	37966255	8	-	27260156	MEWO	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.051763942241009574	[491]	[472,387,476]	-1	hSpCas9	negative selection	7467242
37965923	37965946	8	+	27260156	MEWO	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.292277947004543	[920]	[1419,832,983]	6	hSpCas9	negative selection	7531522
37965792	37965815	8	-	27260156	MEWO	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.5347373223653897	[196]	[108,149,118]	-8	hSpCas9	negative selection	7531523
37966233	37966256	8	+	27260156	MEWO	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.2156574619592848	[908]	[839,677,699]	-5	hSpCas9	negative selection	7531524
37965257	37965280	8	+	27260156	LNCAPCLONEFGC	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.21604522797339865	[1123]	[801,819,1065,850]	-3	hSpCas9	negative selection	7588491
37966033	37966056	8	-	27260156	LNCAPCLONEFGC	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.2952756834331225	[110]	[48,59,243,163]	4	hSpCas9	negative selection	7588492
37966232	37966255	8	-	27260156	LNCAPCLONEFGC	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.2701010832003906	[491]	[278,296,472,450]	-4	hSpCas9	negative selection	7588493
37965923	37965946	8	+	27260156	LNCAPCLONEFGC	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.3099767836829327	[920]	[859,963,1152,1184]	5	hSpCas9	negative selection	7652773
37965792	37965815	8	-	27260156	LNCAPCLONEFGC	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.06877685381124743	[196]	[224,81,208,241]	1	hSpCas9	negative selection	7652774
37966233	37966256	8	+	27260156	LNCAPCLONEFGC	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.26782529441376945	[908]	[588,685,650,805]	-4	hSpCas9	negative selection	7652775
37965257	37965280	8	+	27260156	PANC0327	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.08809303138530056	[1123]	[1103,1131,1299,703]	1	hSpCas9	negative selection	7709742
37966033	37966056	8	-	27260156	PANC0327	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.8169996097903767	[110]	[470,42,119,101]	9	hSpCas9	negative selection	7709743
37966232	37966255	8	-	27260156	PANC0327	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.0002614813774784591	[491]	[368,522,552,286]	0	hSpCas9	negative selection	7709744
37965923	37965946	8	+	27260156	PANC0327	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.047788492802784854	[920]	[1135,530,905,873]	0	hSpCas9	negative selection	7774024
37965792	37965815	8	-	27260156	PANC0327	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.38572868027347895	[196]	[113,141,115,160]	-5	hSpCas9	negative selection	7774025
37966233	37966256	8	+	27260156	PANC0327	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.28592878893721607	[908]	[772,703,750,424]	-4	hSpCas9	negative selection	7774026
37965257	37965280	8	+	27260156	NCIH2009	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.18517297246629405	[1123]	[2117,1626,1676]	2	hSpCas9	negative selection	7830993
37966033	37966056	8	-	27260156	NCIH2009	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.5380454866990185	[110]	[180,193,291]	7	hSpCas9	negative selection	7830994
37966232	37966255	8	-	27260156	NCIH2009	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.3140035788334341	[491]	[1121,746,747]	4	hSpCas9	negative selection	7830995
37965923	37965946	8	+	27260156	NCIH2009	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.6006389113416054	[920]	[2441,2031,1471]	8	hSpCas9	negative selection	7895275
37965792	37965815	8	-	27260156	NCIH2009	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.34615657318756066	[196]	[427,265,371]	5	hSpCas9	negative selection	7895276
37966233	37966256	8	+	27260156	NCIH2009	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.1276248452365606	[908]	[1021,1257,1175]	-2	hSpCas9	negative selection	7895277
37965257	37965280	8	+	27260156	NCIH1373	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.19932378351295066	[1123]	[1748,1530,1044,394]	2	hSpCas9	negative selection	7952244
37966033	37966056	8	-	27260156	NCIH1373	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.21909347531022294	[110]	[281,71,179,17]	2	hSpCas9	negative selection	7952245
37966232	37966255	8	-	27260156	NCIH1373	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.2809126383515643	[491]	[660,537,463,276]	2	hSpCas9	negative selection	7952246
37965923	37965946	8	+	27260156	NCIH1373	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.6119188251875262	[920]	[1729,1555,1538,393]	6	hSpCas9	negative selection	8016526
37965792	37965815	8	-	27260156	NCIH1373	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.13965839210380393	[196]	[255,305,106,79]	1	hSpCas9	negative selection	8016527
37966233	37966256	8	+	27260156	NCIH1373	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.15090537443649155	[908]	[1063,877,1083,169]	-1	hSpCas9	negative selection	8016528
37965257	37965280	8	+	27260156	PATU8902	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.14211633737881413	[1123]	[1229,2483,932,1110]	-1	hSpCas9	negative selection	8073495
37966033	37966056	8	-	27260156	PATU8902	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.05084107839271024	[110]	[211,73,207,127]	0	hSpCas9	negative selection	8073496
37966232	37966255	8	-	27260156	PATU8902	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.20419668447656045	[491]	[779,1005,450,1031]	2	hSpCas9	negative selection	8073497
37965923	37965946	8	+	27260156	PATU8902	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.941124208242864	[920]	[2395,3466,1872,2223]	8	hSpCas9	negative selection	8137777
37965792	37965815	8	-	27260156	PATU8902	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.7559732905778089	[196]	[303,344,390,879]	7	hSpCas9	negative selection	8137778
37966233	37966256	8	+	27260156	PATU8902	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.043278399372015275	[908]	[1107,1061,1119,1699]	0	hSpCas9	negative selection	8137779
37965257	37965280	8	+	27260156	PANC1	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.1926630654745356	[1123]	[622,936,940,881]	-3	hSpCas9	negative selection	8194746
37966033	37966056	8	-	27260156	PANC1	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.10570343681425243	[110]	[99,55,100,88]	-2	hSpCas9	negative selection	8194747
37966232	37966255	8	-	27260156	PANC1	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.06204021967724077	[491]	[389,478,475,300]	-1	hSpCas9	negative selection	8194748
37965923	37965946	8	+	27260156	PANC1	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.306464148404744	[920]	[1033,1275,989,702]	5	hSpCas9	negative selection	8259028
37965792	37965815	8	-	27260156	PANC1	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.27734487698179433	[196]	[113,147,93,192]	-4	hSpCas9	negative selection	8259029
37966233	37966256	8	+	27260156	PANC1	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.2883479232276125	[908]	[605,735,891,378]	-4	hSpCas9	negative selection	8259030
37965257	37965280	8	+	27260156	PANC0813	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	0.015380912278403214	[1123]	[1613,1444,1230,1084]	0	hSpCas9	negative selection	8315997
37966033	37966056	8	-	27260156	PANC0813	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.13450456503531294	[110]	[186,144,98,144]	2	hSpCas9	negative selection	8315998
37966232	37966255	8	-	27260156	PANC0813	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.036973696484081414	[491]	[741,478,493,664]	0	hSpCas9	negative selection	8315999
37965923	37965946	8	+	27260156	PANC0813	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.27831614681053896	[920]	[1389,1276,1513,1085]	4	hSpCas9	negative selection	8380279
37965792	37965815	8	-	27260156	PANC0813	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.22307654018050393	[196]	[317,319,211,235]	3	hSpCas9	negative selection	8380280
37966233	37966256	8	+	27260156	PANC0813	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	0.07388429221635351	[908]	[898,1217,953,1385]	1	hSpCas9	negative selection	8380281
37965257	37965280	8	+	27260156	RDES	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.4211512190110154	[1123]	[681,909,1027,1340]	-6	hSpCas9	negative selection	8437248
37966033	37966056	8	-	27260156	RDES	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.23028810434868419	[110]	[83,108,219,212]	4	hSpCas9	negative selection	8437249
37966232	37966255	8	-	27260156	RDES	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.26836884991188015	[491]	[543,666,862,666]	4	hSpCas9	negative selection	8437250
37965923	37965946	8	+	27260156	RDES	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	-0.0831523409459618	[920]	[905,949,1047,1105]	-1	hSpCas9	negative selection	8501530
37965792	37965815	8	-	27260156	RDES	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.026697662638718755	[196]	[154,194,307,290]	0	hSpCas9	negative selection	8501531
37966233	37966256	8	+	27260156	RDES	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.5196987170219182	[908]	[616,766,691,855]	-7	hSpCas9	negative selection	8501532
37965257	37965280	8	+	27260156	PC3	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.3477258825087186	[1123]	[580,746,1398,1053]	-7	hSpCas9	negative selection	8558499
37966033	37966056	8	-	27260156	PC3	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.07174936390087883	[110]	[107,105,131,112]	1	hSpCas9	negative selection	8558500
37966232	37966255	8	-	27260156	PC3	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.08178982058084414	[491]	[371,365,749,466]	-2	hSpCas9	negative selection	8558501
37965923	37965946	8	+	27260156	PC3	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.19463403729560846	[920]	[682,899,1892,1122]	4	hSpCas9	negative selection	8622781
37965792	37965815	8	-	27260156	PC3	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.34977673396978715	[196]	[132,139,551,334]	7	hSpCas9	negative selection	8622782
37966233	37966256	8	+	27260156	PC3	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.2839804512815355	[908]	[511,648,1057,915]	-6	hSpCas9	negative selection	8622783
37965257	37965280	8	+	27260156	PATU8988T	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.26129993317367295	[1123]	[644,1125,1018,848]	-4	hSpCas9	negative selection	8679750
37966033	37966056	8	-	27260156	PATU8988T	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.7027349395214624	[110]	[146,393,94,75]	9	hSpCas9	negative selection	8679751
37966232	37966255	8	-	27260156	PATU8988T	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.3148086202949346	[491]	[528,621,631,583]	5	hSpCas9	negative selection	8679752
37965923	37965946	8	+	27260156	PATU8988T	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.08092286593025888	[920]	[832,906,1077,941]	1	hSpCas9	negative selection	8744032
37965792	37965815	8	-	27260156	PATU8988T	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.020850340137518852	[196]	[48,263,320,138]	0	hSpCas9	negative selection	8744033
37966233	37966256	8	+	27260156	PATU8988T	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.2709818032734338	[908]	[658,1168,376,754]	-4	hSpCas9	negative selection	8744034
37965257	37965280	8	+	27260156	T47D	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.3038923305633596	[1123]	[1018,1131,1039,1044]	-6	hSpCas9	negative selection	8801001
37966033	37966056	8	-	27260156	T47D	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.051122645573497216	[110]	[151,92,80,216]	1	hSpCas9	negative selection	8801002
37966232	37966255	8	-	27260156	T47D	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.23831307145166955	[491]	[447,408,464,632]	-5	hSpCas9	negative selection	8801003
37965923	37965946	8	+	27260156	T47D	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.13647082273265088	[920]	[1240,986,1221,1286]	3	hSpCas9	negative selection	8865283
37965792	37965815	8	-	27260156	T47D	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.3193739317328783	[196]	[158,195,160,219]	-6	hSpCas9	negative selection	8865284
37966233	37966256	8	+	27260156	T47D	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.44251281480236737	[908]	[678,715,887,838]	-7	hSpCas9	negative selection	8865285
37965257	37965280	8	+	27260156	SU8686	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.213102189396688	[1123]	[879,973,1030,962]	-4	hSpCas9	negative selection	8922252
37966033	37966056	8	-	27260156	SU8686	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.20435736666776916	[110]	[117,80,163,155]	3	hSpCas9	negative selection	8922253
37966232	37966255	8	-	27260156	SU8686	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.12136042436728256	[491]	[344,473,528,453]	-2	hSpCas9	negative selection	8922254
37965923	37965946	8	+	27260156	SU8686	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.31367272353875253	[920]	[912,1005,1226,1486]	5	hSpCas9	negative selection	8986534
37965792	37965815	8	-	27260156	SU8686	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.006596753718711268	[196]	[124,159,274,237]	0	hSpCas9	negative selection	8986535
37966233	37966256	8	+	27260156	SU8686	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.2953356169535397	[908]	[713,750,751,711]	-5	hSpCas9	negative selection	8986536
37965257	37965280	8	+	27260156	SKES1	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.20132812565850755	[1123]	[1054,1079,958,836]	-4	hSpCas9	negative selection	9043503
37966033	37966056	8	-	27260156	SKES1	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.03150995574404902	[110]	[117,136,124,78]	0	hSpCas9	negative selection	9043504
37966232	37966255	8	-	27260156	SKES1	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.04485395603785755	[491]	[440,603,638,354]	1	hSpCas9	negative selection	9043505
37965923	37965946	8	+	27260156	SKES1	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.16299535454966374	[920]	[1298,1259,682,941]	3	hSpCas9	negative selection	9107785
37965792	37965815	8	-	27260156	SKES1	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.17487333027609342	[196]	[224,123,166,178]	-4	hSpCas9	negative selection	9107786
37966233	37966256	8	+	27260156	SKES1	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.4031776490379103	[908]	[795,798,589,591]	-7	hSpCas9	negative selection	9107787
37965257	37965280	8	+	27260156	TOV112D	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.10019257946416138	[1123]	[1331,1394,758,827]	-2	hSpCas9	negative selection	9164754
37966033	37966056	8	-	27260156	TOV112D	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	0.49030780395790474	[110]	[103,161,218,136]	8	hSpCas9	negative selection	9164755
37966232	37966255	8	-	27260156	TOV112D	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	0.004595714601063075	[491]	[502,679,673,174]	0	hSpCas9	negative selection	9164756
37965923	37965946	8	+	27260156	TOV112D	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.2170827364903153	[920]	[1064,1293,1016,967]	4	hSpCas9	negative selection	9229036
37965792	37965815	8	-	27260156	TOV112D	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.6809430627545217	[196]	[185,149,80,87]	-8	hSpCas9	negative selection	9229037
37966233	37966256	8	+	27260156	TOV112D	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.1813011102041575	[908]	[692,1132,825,634]	-4	hSpCas9	negative selection	9229038
37965257	37965280	8	+	27260156	TC71	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.3049761440941051	[1123]	[862,1115,923,1003]	-7	hSpCas9	negative selection	9286005
37966033	37966056	8	-	27260156	TC71	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.30332114218326467	[110]	[79,178,63,61]	-7	hSpCas9	negative selection	9286006
37966232	37966255	8	-	27260156	TC71	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.0005269801806628005	[491]	[545,501,444,623]	0	hSpCas9	negative selection	9286007
37965923	37965946	8	+	27260156	TC71	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	0.11857650864603786	[920]	[1063,1104,1098,1014]	3	hSpCas9	negative selection	9350287
37965792	37965815	8	-	27260156	TC71	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	-0.10565496090933912	[196]	[188,272,132,191]	-3	hSpCas9	negative selection	9350288
37966233	37966256	8	+	27260156	TC71	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.37963939930182844	[908]	[742,788,615,858]	-8	hSpCas9	negative selection	9350289
37965257	37965280	8	+	27260156	TC32	viability	TTACCTACCCGTCGAGCCGTTGG	ADRB3	ENSG00000188778	-0.44572462281190517	[1123]	[704,592,1041,843]	-7	hSpCas9	negative selection	9407256
37966033	37966056	8	-	27260156	TC32	viability	GTGACCAACCCGCTGCGTTACGG	ADRB3	ENSG00000188778	-0.4968150746154434	[110]	[74,59,81,80]	-7	hSpCas9	negative selection	9407257
37966232	37966255	8	-	27260156	TC32	viability	CAACGTGTTCGTGACTTCGCTGG	ADRB3	ENSG00000188778	-0.046783451807944146	[491]	[550,303,591,377]	-1	hSpCas9	negative selection	9407258
37965923	37965946	8	+	27260156	TC32	viability	CGGCCCCTACGCGCCACCACTGG	ADRB3	ENSG00000188778	-0.04255875984446722	[920]	[773,547,1287,903]	0	hSpCas9	negative selection	9471538
37965792	37965815	8	-	27260156	TC32	viability	TGATGCTCTTCGTCTACGCGCGG	ADRB3	ENSG00000188778	0.11720223043355893	[196]	[67,182,405,193]	2	hSpCas9	negative selection	9471539
37966233	37966256	8	+	27260156	TC32	viability	CAGCGAAGTCACGAACACGTTGG	ADRB3	ENSG00000188778	-0.5069792572300666	[908]	[684,351,739,705]	-7	hSpCas9	negative selection	9471540
37965264	37965287	8	-	27869803	HPAFII	viability after 27 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	1.5294702831114366	[94]	[147,140,NaN]	9	hSpCas9	negative selection	9602545
37965377	37965400	8	+	27869803	HPAFII	viability after 27 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.9827823331396202	[311]	[34,122,NaN]	-6	hSpCas9	negative selection	9602546
37965802	37965825	8	+	27869803	HPAFII	viability after 27 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.3954384074574157	[420]	[68,250,NaN]	-3	hSpCas9	negative selection	9602547
37965939	37965962	8	-	27869803	HPAFII	viability after 27 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.3650421360411375	[411]	[153,179,NaN]	-3	hSpCas9	negative selection	9602548
37965264	37965287	8	-	27869803	HPAFII	viability after 15 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	1.0821900238263595	[94]	[246,196,NaN]	9	hSpCas9	negative selection	9684994
37965377	37965400	8	+	27869803	HPAFII	viability after 15 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.5731391009505462	[311]	[225,224,NaN]	-6	hSpCas9	negative selection	9684995
37965802	37965825	8	+	27869803	HPAFII	viability after 15 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.00023029812433617014	[420]	[454,450,NaN]	0	hSpCas9	negative selection	9684996
37965939	37965962	8	-	27869803	HPAFII	viability after 15 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.16863113421793596	[411]	[575,448,NaN]	2	hSpCas9	negative selection	9684997
37965264	37965287	8	-	27869803	ASPC1	viability after 36 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	-0.5140317788281883	[298]	[25,133,56]	-5	hSpCas9	negative selection	9767443
37965377	37965400	8	+	27869803	ASPC1	viability after 36 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	1.2686276345425762	[598]	[934,441,244]	9	hSpCas9	negative selection	9767444
37965802	37965825	8	+	27869803	ASPC1	viability after 36 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.6509166369483884	[971]	[801,357,476]	6	hSpCas9	negative selection	9767445
37965939	37965962	8	-	27869803	ASPC1	viability after 36 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.6828315097558766	[773]	[565,345,405]	6	hSpCas9	negative selection	9767446
37965264	37965287	8	-	27869803	PATU8988S	viability after 35 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	0.4823328781231333	[207]	[129,103,NaN]	5	hSpCas9	negative selection	9849892
37965377	37965400	8	+	27869803	PATU8988S	viability after 35 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.6086274681932259	[503]	[315,302,NaN]	6	hSpCas9	negative selection	9849893
37965802	37965825	8	+	27869803	PATU8988S	viability after 35 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.023265239356596523	[950]	[546,205,NaN]	0	hSpCas9	negative selection	9849894
37965939	37965962	8	-	27869803	PATU8988S	viability after 35 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.2265841112357768	[675]	[95,369,NaN]	-2	hSpCas9	negative selection	9849895
37965264	37965287	8	-	27869803	PATU8988S	viability after 31 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	0.6046309346202883	[207]	[104,152,NaN]	7	hSpCas9	negative selection	9932341
37965377	37965400	8	+	27869803	PATU8988S	viability after 31 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	0.34125531802843007	[503]	[236,276,NaN]	4	hSpCas9	negative selection	9932342
37965802	37965825	8	+	27869803	PATU8988S	viability after 31 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	-0.18979599915659007	[950]	[430,206,NaN]	-2	hSpCas9	negative selection	9932343
37965939	37965962	8	-	27869803	PATU8988S	viability after 31 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	0.0020640542300477405	[675]	[155,414,NaN]	0	hSpCas9	negative selection	9932344
37965264	37965287	8	-	27869803	HPAFII	viability after 35 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	1.798427731118825	[94]	[155,179,NaN]	9	hSpCas9	negative selection	10014790
37965377	37965400	8	+	27869803	HPAFII	viability after 35 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.9041560847913557	[311]	[58,112,NaN]	-5	hSpCas9	negative selection	10014791
37965802	37965825	8	+	27869803	HPAFII	viability after 35 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.6232674371317333	[420]	[94,590,NaN]	4	hSpCas9	negative selection	10014792
37965939	37965962	8	-	27869803	HPAFII	viability after 35 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.136177945282565	[411]	[114,273,NaN]	-1	hSpCas9	negative selection	10014793
37965264	37965287	8	-	27869803	HPAFII	viability after 31 days	GGCTTTGCCAACGGCTCGACGGG	ADRB3	ENSG00000188778	1.4071539012663463	[94]	[127,155,NaN]	9	hSpCas9	negative selection	10097239
37965377	37965400	8	+	27869803	HPAFII	viability after 31 days	GGCCGCAGCGGCACAGAAGACGG	ADRB3	ENSG00000188778	-0.5463431706601294	[311]	[72,170,NaN]	-4	hSpCas9	negative selection	10097240
37965802	37965825	8	+	27869803	HPAFII	viability after 31 days	ACGAAGAGCATCACGAGAAGAGG	ADRB3	ENSG00000188778	0.19090648795710274	[420]	[128,422,NaN]	1	hSpCas9	negative selection	10097241
37965939	37965962	8	-	27869803	HPAFII	viability after 31 days	TTGCGCCCATCATGAGCCAGTGG	ADRB3	ENSG00000188778	-0.35533450393553334	[411]	[174,186,NaN]	-2	hSpCas9	negative selection	10097242
37965951	37965974	8	+	28162770	P31FUJ	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.8156963132768112	[116]	[241]	8	hSpCas9	negative selection	10107754
37965791	37965814	8	-	28162770	P31FUJ	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	1.3861076282301155	[13]	[42]	9	hSpCas9	negative selection	10107755
37966266	37966289	8	+	28162770	P31FUJ	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.017534217511312233	[86]	[100]	0	hSpCas9	negative selection	10107756
37966164	37966187	8	+	28162770	P31FUJ	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-1.257585305344267	[410]	[201]	-7	hSpCas9	negative selection	10107757
37966131	37966154	8	-	28162770	P31FUJ	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.28592659790669084	[103]	[148]	3	hSpCas9	negative selection	10107758
37966083	37966106	8	+	28162770	P31FUJ	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.14238578225789889	[467]	[606]	1	hSpCas9	negative selection	10107759
37965968	37965991	8	-	28162770	P31FUJ	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	-0.32698464347108636	[268]	[251]	-3	hSpCas9	negative selection	10107760
37965871	37965894	8	+	28162770	P31FUJ	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.010820894973194127	[211]	[250]	0	hSpCas9	negative selection	10107761
37965840	37965863	8	+	28162770	P31FUJ	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.4336212138024748	[176]	[153]	-4	hSpCas9	negative selection	10107762
37965825	37965848	8	+	28162770	P31FUJ	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.776808030912677	[190]	[130]	-6	hSpCas9	negative selection	10107763
37965951	37965974	8	+	28162770	TF1	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10277120
37965791	37965814	8	-	28162770	TF1	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	NaN	[NaN]	[17]	1	hSpCas9	negative selection	10277121
37966266	37966289	8	+	28162770	TF1	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10277122
37966164	37966187	8	+	28162770	TF1	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	NaN	[NaN]	[176]	1	hSpCas9	negative selection	10277123
37966131	37966154	8	-	28162770	TF1	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10277124
37966083	37966106	8	+	28162770	TF1	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	NaN	[NaN]	[393]	1	hSpCas9	negative selection	10277125
37965968	37965991	8	-	28162770	TF1	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	NaN	[NaN]	[200]	1	hSpCas9	negative selection	10277126
37965871	37965894	8	+	28162770	TF1	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10277127
37965840	37965863	8	+	28162770	TF1	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10277128
37965825	37965848	8	+	28162770	TF1	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10277129
37965951	37965974	8	+	28162770	SKM1	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.47567885061867965	[23]	[58]	4	hSpCas9	negative selection	10446486
37965791	37965814	8	-	28162770	SKM1	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	0.5565099252317243	[4]	[12]	5	hSpCas9	negative selection	10446487
37966266	37966289	8	+	28162770	SKM1	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.12685627955042644	[41]	[67]	-1	hSpCas9	negative selection	10446488
37966164	37966187	8	+	28162770	SKM1	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.44241303474745136	[102]	[133]	-4	hSpCas9	negative selection	10446489
37966131	37966154	8	-	28162770	SKM1	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.811870403180097	[28]	[89]	7	hSpCas9	negative selection	10446490
37966083	37966106	8	+	28162770	SKM1	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.7484247095412704	[132]	[394]	7	hSpCas9	negative selection	10446491
37965968	37965991	8	-	28162770	SKM1	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.34464817138744597	[48]	[109]	3	hSpCas9	negative selection	10446492
37965871	37965894	8	+	28162770	SKM1	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	1.1858178064372937	[45]	[184]	9	hSpCas9	negative selection	10446493
37965840	37965863	8	+	28162770	SKM1	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	0.03360839264281967	[20]	[37]	0	hSpCas9	negative selection	10446494
37965825	37965848	8	+	28162770	SKM1	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.5418937788292701	[27]	[33]	-4	hSpCas9	negative selection	10446495
37965951	37965974	8	+	28162770	SKM1	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.47567885061867965	[23]	[58]	4	hSpCas9	negative selection	10615852
37965791	37965814	8	-	28162770	SKM1	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	0.5565099252317243	[4]	[12]	5	hSpCas9	negative selection	10615853
37966266	37966289	8	+	28162770	SKM1	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.12685627955042644	[41]	[67]	-1	hSpCas9	negative selection	10615854
37966164	37966187	8	+	28162770	SKM1	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.44241303474745136	[102]	[133]	-4	hSpCas9	negative selection	10615855
37966131	37966154	8	-	28162770	SKM1	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.811870403180097	[28]	[89]	7	hSpCas9	negative selection	10615856
37966083	37966106	8	+	28162770	SKM1	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.7484247095412704	[132]	[394]	7	hSpCas9	negative selection	10615857
37965968	37965991	8	-	28162770	SKM1	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.34464817138744597	[48]	[109]	3	hSpCas9	negative selection	10615858
37965871	37965894	8	+	28162770	SKM1	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	1.1858178064372937	[45]	[184]	9	hSpCas9	negative selection	10615859
37965840	37965863	8	+	28162770	SKM1	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	0.03360839264281967	[20]	[37]	0	hSpCas9	negative selection	10615860
37965825	37965848	8	+	28162770	SKM1	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.5418937788292701	[27]	[33]	-4	hSpCas9	negative selection	10615861
37965951	37965974	8	+	28162770	PL21	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	-0.3287888513175079	[100]	[34]	-2	hSpCas9	negative selection	10785218
37965791	37965814	8	-	28162770	PL21	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	-2.1217884803980427	[29]	[2]	-8	hSpCas9	negative selection	10785219
37966266	37966289	8	+	28162770	PL21	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	0.2590333035428888	[95]	[49]	2	hSpCas9	negative selection	10785220
37966164	37966187	8	+	28162770	PL21	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.3400845714665516	[380]	[130]	-2	hSpCas9	negative selection	10785221
37966131	37966154	8	-	28162770	PL21	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.5592207077941485	[91]	[58]	5	hSpCas9	negative selection	10785222
37966083	37966106	8	+	28162770	PL21	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.14614472484859076	[489]	[235]	1	hSpCas9	negative selection	10785223
37965968	37965991	8	-	28162770	PL21	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	1.1750486335264898	[173]	[170]	8	hSpCas9	negative selection	10785224
37965871	37965894	8	+	28162770	PL21	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.3296503474857244	[180]	[98]	3	hSpCas9	negative selection	10785225
37965840	37965863	8	+	28162770	PL21	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	0.9079588629960099	[59]	[48]	7	hSpCas9	negative selection	10785226
37965825	37965848	8	+	28162770	PL21	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	0.07938745502870997	[136]	[62]	0	hSpCas9	negative selection	10785227
37965951	37965974	8	+	28162770	P31FUJ	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.8156963132768112	[116]	[241]	8	hSpCas9	negative selection	10954584
37965791	37965814	8	-	28162770	P31FUJ	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	1.3861076282301155	[13]	[42]	9	hSpCas9	negative selection	10954585
37966266	37966289	8	+	28162770	P31FUJ	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.017534217511312233	[86]	[100]	0	hSpCas9	negative selection	10954586
37966164	37966187	8	+	28162770	P31FUJ	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-1.257585305344267	[410]	[201]	-7	hSpCas9	negative selection	10954587
37966131	37966154	8	-	28162770	P31FUJ	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.28592659790669084	[103]	[148]	3	hSpCas9	negative selection	10954588
37966083	37966106	8	+	28162770	P31FUJ	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.14238578225789889	[467]	[606]	1	hSpCas9	negative selection	10954589
37965968	37965991	8	-	28162770	P31FUJ	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	-0.32698464347108636	[268]	[251]	-3	hSpCas9	negative selection	10954590
37965871	37965894	8	+	28162770	P31FUJ	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.010820894973194127	[211]	[250]	0	hSpCas9	negative selection	10954591
37965840	37965863	8	+	28162770	P31FUJ	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.4336212138024748	[176]	[153]	-4	hSpCas9	negative selection	10954592
37965825	37965848	8	+	28162770	P31FUJ	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.776808030912677	[190]	[130]	-6	hSpCas9	negative selection	10954593
37965951	37965974	8	+	28162770	OCIAML5	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.00037624072214514914	[71]	[129]	0	hSpCas9	negative selection	11123950
37965791	37965814	8	-	28162770	OCIAML5	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	1.8483731472770955	[3]	[25]	9	hSpCas9	negative selection	11123951
37966266	37966289	8	+	28162770	OCIAML5	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-1.5890321650302033	[69]	[41]	-7	hSpCas9	negative selection	11123952
37966164	37966187	8	+	28162770	OCIAML5	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-1.937927307517835	[224]	[105]	-8	hSpCas9	negative selection	11123953
37966131	37966154	8	-	28162770	OCIAML5	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.4280413483287382	[34]	[84]	3	hSpCas9	negative selection	11123954
37966083	37966106	8	+	28162770	OCIAML5	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	-0.4212460743442257	[249]	[336]	-3	hSpCas9	negative selection	11123955
37965968	37965991	8	-	28162770	OCIAML5	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.3138115975156136	[118]	[266]	2	hSpCas9	negative selection	11123956
37965871	37965894	8	+	28162770	OCIAML5	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.5678366835866627	[110]	[296]	5	hSpCas9	negative selection	11123957
37965840	37965863	8	+	28162770	OCIAML5	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-1.6485331767788651	[98]	[56]	-7	hSpCas9	negative selection	11123958
37965825	37965848	8	+	28162770	OCIAML5	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.99711690366728	[114]	[103]	-6	hSpCas9	negative selection	11123959
37965951	37965974	8	+	28162770	EOL1	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	-0.4924700918365501	[242]	[90]	-4	hSpCas9	negative selection	11293316
37965791	37965814	8	-	28162770	EOL1	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	-1.1458415563208635	[41]	[9]	-6	hSpCas9	negative selection	11293317
37966266	37966289	8	+	28162770	EOL1	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	0.5433319393884266	[266]	[204]	5	hSpCas9	negative selection	11293318
37966164	37966187	8	+	28162770	EOL1	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.6415248351797016	[606]	[204]	-4	hSpCas9	negative selection	11293319
37966131	37966154	8	-	28162770	EOL1	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.16896649923698148	[129]	[76]	1	hSpCas9	negative selection	11293320
37966083	37966106	8	+	28162770	EOL1	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.7385874198908924	[768]	[675]	6	hSpCas9	negative selection	11293321
37965968	37965991	8	-	28162770	EOL1	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.31912116828966275	[212]	[139]	3	hSpCas9	negative selection	11293322
37965871	37965894	8	+	28162770	EOL1	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	-0.17580275376193427	[252]	[117]	-1	hSpCas9	negative selection	11293323
37965840	37965863	8	+	28162770	EOL1	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.6138721432135916	[121]	[41]	-4	hSpCas9	negative selection	11293324
37965825	37965848	8	+	28162770	EOL1	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	0.6577612308756332	[153]	[127]	6	hSpCas9	negative selection	11293325
37965951	37965974	8	+	28162770	MOLM13	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	-0.01922579577843264	[170]	[121]	0	hSpCas9	negative selection	11462682
37965791	37965814	8	-	28162770	MOLM13	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	0.2396203938714616	[40]	[34]	1	hSpCas9	negative selection	11462683
37966266	37966289	8	+	28162770	MOLM13	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.9950825947979671	[203]	[73]	-5	hSpCas9	negative selection	11462684
37966164	37966187	8	+	28162770	MOLM13	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-1.2892540945592577	[479]	[141]	-6	hSpCas9	negative selection	11462685
37966131	37966154	8	-	28162770	MOLM13	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.8083138200493307	[123]	[156]	6	hSpCas9	negative selection	11462686
37966083	37966106	8	+	28162770	MOLM13	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	-0.348398665283033	[647]	[367]	-2	hSpCas9	negative selection	11462687
37965968	37965991	8	-	28162770	MOLM13	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.36887937571341306	[195]	[182]	2	hSpCas9	negative selection	11462688
37965871	37965894	8	+	28162770	MOLM13	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	-1.0563190880974809	[278]	[96]	-5	hSpCas9	negative selection	11462689
37965840	37965863	8	+	28162770	MOLM13	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-1.908831186183163	[160]	[30]	-7	hSpCas9	negative selection	11462690
37965825	37965848	8	+	28162770	MOLM13	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-1.7426776043950796	[161]	[34]	-7	hSpCas9	negative selection	11462691
37965951	37965974	8	+	28162770	HEL	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.9212032784037567	[154]	[187]	7	hSpCas9	negative selection	11632048
37965791	37965814	8	-	28162770	HEL	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	1.6737657276209814	[22]	[46]	9	hSpCas9	negative selection	11632049
37966266	37966289	8	+	28162770	HEL	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.8426879951698847	[153]	[54]	-5	hSpCas9	negative selection	11632050
37966164	37966187	8	+	28162770	HEL	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.2616835080174118	[437]	[233]	-2	hSpCas9	negative selection	11632051
37966131	37966154	8	-	28162770	HEL	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	1.529528221552366	[105]	[195]	9	hSpCas9	negative selection	11632052
37966083	37966106	8	+	28162770	HEL	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.49393817059365097	[499]	[450]	4	hSpCas9	negative selection	11632053
37965968	37965991	8	-	28162770	HEL	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.1906706017765461	[170]	[124]	1	hSpCas9	negative selection	11632054
37965871	37965894	8	+	28162770	HEL	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.6062129559752429	[239]	[233]	5	hSpCas9	negative selection	11632055
37965840	37965863	8	+	28162770	HEL	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	0.39193072849982247	[93]	[78]	3	hSpCas9	negative selection	11632056
37965825	37965848	8	+	28162770	HEL	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-2.226677058189499	[189]	[25]	-8	hSpCas9	negative selection	11632057
37965951	37965974	8	+	28162770	MV411	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.7379652496458824	[120]	[169]	6	hSpCas9	negative selection	11801414
37965791	37965814	8	-	28162770	MV411	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	-0.33752494993838145	[8]	[5]	-3	hSpCas9	negative selection	11801415
37966266	37966289	8	+	28162770	MV411	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-1.2968829654410348	[104]	[35]	-7	hSpCas9	negative selection	11801416
37966164	37966187	8	+	28162770	MV411	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.415527461939654	[341]	[215]	-3	hSpCas9	negative selection	11801417
37966131	37966154	8	-	28162770	MV411	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	0.6017210189825228	[96]	[123]	5	hSpCas9	negative selection	11801418
37966083	37966106	8	+	28162770	MV411	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	-0.08908792031754498	[446]	[353]	0	hSpCas9	negative selection	11801419
37965968	37965991	8	-	28162770	MV411	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	1.4350645539585467	[161]	[368]	9	hSpCas9	negative selection	11801420
37965871	37965894	8	+	28162770	MV411	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.64458489116573	[141]	[186]	6	hSpCas9	negative selection	11801421
37965840	37965863	8	+	28162770	MV411	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.31105273857718974	[80]	[54]	-2	hSpCas9	negative selection	11801422
37965825	37965848	8	+	28162770	MV411	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-2.085545732613583	[130]	[25]	-8	hSpCas9	negative selection	11801423
37965951	37965974	8	+	28162770	MONOMAC1	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.9322461698854128	[79]	[174]	8	hSpCas9	negative selection	11970780
37965791	37965814	8	-	28162770	MONOMAC1	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	4.326525108997459	[0]	[22]	9	hSpCas9	negative selection	11970781
37966266	37966289	8	+	28162770	MONOMAC1	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	0.4364241713527925	[77]	[120]	4	hSpCas9	negative selection	11970782
37966164	37966187	8	+	28162770	MONOMAC1	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-1.2652083497011328	[259]	[123]	-7	hSpCas9	negative selection	11970783
37966131	37966154	8	-	28162770	MONOMAC1	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	1.0115497747518638	[44]	[103]	8	hSpCas9	negative selection	11970784
37966083	37966106	8	+	28162770	MONOMAC1	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.1015358511617781	[273]	[336]	1	hSpCas9	negative selection	11970785
37965968	37965991	8	-	28162770	MONOMAC1	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.6044174735583662	[104]	[182]	6	hSpCas9	negative selection	11970786
37965871	37965894	8	+	28162770	MONOMAC1	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	-0.33586455175687047	[108]	[98]	-3	hSpCas9	negative selection	11970787
37965840	37965863	8	+	28162770	MONOMAC1	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.22303205559249806	[55]	[54]	-2	hSpCas9	negative selection	11970788
37965825	37965848	8	+	28162770	MONOMAC1	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	0.03490988099014308	[85]	[100]	0	hSpCas9	negative selection	11970789
37965951	37965974	8	+	28162770	OCIAML2	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	0.14535957109961944	[22]	[140]	1	hSpCas9	negative selection	12140146
37965791	37965814	8	-	28162770	OCIAML2	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	-0.8076648125197319	[5]	[18]	-5	hSpCas9	negative selection	12140147
37966266	37966289	8	+	28162770	OCIAML2	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.22270231179857572	[31]	[151]	-2	hSpCas9	negative selection	12140148
37966164	37966187	8	+	28162770	OCIAML2	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.8455898851456697	[70]	[218]	-5	hSpCas9	negative selection	12140149
37966131	37966154	8	-	28162770	OCIAML2	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	-0.09211820198843135	[19]	[103]	-1	hSpCas9	negative selection	12140150
37966083	37966106	8	+	28162770	OCIAML2	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.4727866463914714	[77]	[599]	4	hSpCas9	negative selection	12140151
37965968	37965991	8	-	28162770	OCIAML2	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.8331509229349419	[23]	[236]	7	hSpCas9	negative selection	12140152
37965871	37965894	8	+	28162770	OCIAML2	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	0.09571699731164784	[25]	[153]	0	hSpCas9	negative selection	12140153
37965840	37965863	8	+	28162770	OCIAML2	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	-0.34351790733882204	[18]	[82]	-3	hSpCas9	negative selection	12140154
37965825	37965848	8	+	28162770	OCIAML2	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.3953416979379243	[27]	[117]	-3	hSpCas9	negative selection	12140155
37965951	37965974	8	+	28162770	OCIAML3	viability	GATGGGCGCAAACGACACCGCGG	ADRB3	ENSG00000188778	1.0440661968565552	[39]	[248]	8	hSpCas9	negative selection	12309512
37965791	37965814	8	-	28162770	OCIAML3	viability	GATGCTCTTCGTCTACGCGCGGG	ADRB3	ENSG00000188778	-1.079434467494405	[6]	[9]	-6	hSpCas9	negative selection	12309513
37966266	37966289	8	+	28162770	OCIAML3	viability	GAGTCTCGGAGTCCAGGCGATGG	ADRB3	ENSG00000188778	-0.786652718266559	[23]	[41]	-5	hSpCas9	negative selection	12309514
37966164	37966187	8	+	28162770	OCIAML3	viability	GTGGCCAGTCAGCGCCAAGGTGG	ADRB3	ENSG00000188778	-0.43173621142528606	[104]	[234]	-3	hSpCas9	negative selection	12309515
37966131	37966154	8	-	28162770	OCIAML3	viability	GCGCCACTGGCTGCGAGCTGTGG	ADRB3	ENSG00000188778	-0.9750978076796694	[27]	[42]	-6	hSpCas9	negative selection	12309516
37966083	37966106	8	+	28162770	OCIAML3	viability	GCACAGGGTTTCGATGCTGGCGG	ADRB3	ENSG00000188778	0.2791623374403541	[100]	[369]	2	hSpCas9	negative selection	12309517
37965968	37965991	8	-	28162770	OCIAML3	viability	GGTGTGGGTCGTGTCGGCCGCGG	ADRB3	ENSG00000188778	0.6015431687936437	[30]	[141]	5	hSpCas9	negative selection	12309518
37965871	37965894	8	+	28162770	OCIAML3	viability	GAGGCGAAGGCACAGCAGCGCGG	ADRB3	ENSG00000188778	-0.6074281560864848	[53]	[106]	-4	hSpCas9	negative selection	12309519
37965840	37965863	8	+	28162770	OCIAML3	viability	GGAGGAGGACAGCAGCACGTAGG	ADRB3	ENSG00000188778	1.5195549184990367	[28]	[250]	9	hSpCas9	negative selection	12309520
37965825	37965848	8	+	28162770	OCIAML3	viability	AAGGTAGAAGGAGACGGAGGAGG	ADRB3	ENSG00000188778	-0.2561380015677792	[35]	[90]	-2	hSpCas9	negative selection	12309521