Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:326
• Symbol:AIRE
• Description:autoimmune regulator

DataSource: http://genomecrispr.dkfz.de/#!/results/AIRE

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
44286045	44286068	21	+	26472758	Jiyoye	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.18760900424818883	[84]	[72]	1	hSpCas9	negative selection	4601
44293823	44293846	21	+	26472758	Jiyoye	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	0.0911478880581954	[60]	[48]	0	hSpCas9	negative selection	4602
44286987	44287010	21	+	26472758	Jiyoye	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	0.24963410451939344	[115]	[103]	2	hSpCas9	negative selection	4603
44286562	44286585	21	+	26472758	Jiyoye	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	4.494638222756212	[0]	[16]	9	hSpCas9	negative selection	4604
44286601	44286624	21	-	26472758	Jiyoye	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.9440907078199209	[172]	[250]	6	hSpCas9	negative selection	4605
44289734	44289757	21	+	26472758	Jiyoye	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.36996430240880085	[431]	[420]	2	hSpCas9	negative selection	4606
44290028	44290051	21	-	26472758	Jiyoye	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	1.4071753815058727	[0]	[1]	8	hSpCas9	negative selection	4607
44291186	44291209	21	-	26472758	Jiyoye	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	1.96590634065385	[36]	[108]	8	hSpCas9	negative selection	4608
44293110	44293133	21	-	26472758	Jiyoye	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-0.9596069491657493	[195]	[75]	-6	hSpCas9	negative selection	4609
44293143	44293166	21	-	26472758	Jiyoye	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	0.20364198742074135	[341]	[296]	1	hSpCas9	negative selection	4610
44286045	44286068	21	+	26472758	KBM7	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.32352130367510573	[519,383]	[231,290]	3	hSpCas9	negative selection	195719
44293823	44293846	21	+	26472758	KBM7	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	-0.005918640672321451	[277,399]	[191,135]	0	hSpCas9	negative selection	195720
44286987	44287010	21	+	26472758	KBM7	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	0.42741597425426303	[490,193]	[235,182]	4	hSpCas9	negative selection	195721
44286562	44286585	21	+	26472758	KBM7	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	0.3791321942646153	[52,85]	[76,13]	4	hSpCas9	negative selection	195722
44286601	44286624	21	-	26472758	KBM7	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.015852251097289216	[710,463]	[271,276]	0	hSpCas9	negative selection	195723
44289734	44289757	21	+	26472758	KBM7	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.7068552327265969	[1535,1052]	[1170,807]	7	hSpCas9	negative selection	195724
44290028	44290051	21	-	26472758	KBM7	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-2.5894738661040457	[43,19]	[3,0]	-9	hSpCas9	negative selection	195725
44291186	44291209	21	-	26472758	KBM7	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	0.2848751331117071	[404,238]	[142,213]	3	hSpCas9	negative selection	195726
44293110	44293133	21	-	26472758	KBM7	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-0.2930314557728231	[755,485]	[211,253]	-3	hSpCas9	negative selection	195727
44293143	44293166	21	-	26472758	KBM7	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	0.2594749331338031	[1907,1884]	[921,1205]	2	hSpCas9	negative selection	195728
44286045	44286068	21	+	26472758	Raji	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-0.4083163029104431	[182]	[31]	-3	hSpCas9	negative selection	386837
44293823	44293846	21	+	26472758	Raji	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	0.14961177076289678	[100]	[25]	1	hSpCas9	negative selection	386838
44286987	44287010	21	+	26472758	Raji	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	0.8323764878737298	[241]	[99]	7	hSpCas9	negative selection	386839
44286562	44286585	21	+	26472758	Raji	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	2.217008026548098	[37]	[40]	9	hSpCas9	negative selection	386840
44286601	44286624	21	-	26472758	Raji	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	-0.1697746893937404	[348]	[71]	-1	hSpCas9	negative selection	386841
44289734	44289757	21	+	26472758	Raji	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.7407264984656481	[605]	[234]	7	hSpCas9	negative selection	386842
44290028	44290051	21	-	26472758	Raji	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	2.107383535373599	[6]	[6]	9	hSpCas9	negative selection	386843
44291186	44291209	21	-	26472758	Raji	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	0.44917205262180465	[201]	[63]	4	hSpCas9	negative selection	386844
44293110	44293133	21	-	26472758	Raji	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-0.6687204526995649	[410]	[59]	-5	hSpCas9	negative selection	386845
44293143	44293166	21	-	26472758	Raji	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.24015520319280048	[1022]	[200]	-2	hSpCas9	negative selection	386846
44286045	44286068	21	+	26472758	K562	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	1.2381597371947648	[230]	[459]	9	hSpCas9	negative selection	577955
44293823	44293846	21	+	26472758	K562	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	0.005631868079330471	[235]	[199]	0	hSpCas9	negative selection	577956
44286987	44287010	21	+	26472758	K562	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	1.4618619330311615	[291]	[678]	9	hSpCas9	negative selection	577957
44286562	44286585	21	+	26472758	K562	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-0.893084796083488	[142]	[64]	-5	hSpCas9	negative selection	577958
44286601	44286624	21	-	26472758	K562	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	-0.5739073122121605	[461]	[261]	-4	hSpCas9	negative selection	577959
44289734	44289757	21	+	26472758	K562	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.2362447962207468	[1061]	[1055]	1	hSpCas9	negative selection	577960
44290028	44290051	21	-	26472758	K562	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-1.0775093672209155	[64]	[25]	-5	hSpCas9	negative selection	577961
44291186	44291209	21	-	26472758	K562	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	1.0828961672198316	[320]	[573]	8	hSpCas9	negative selection	577962
44293110	44293133	21	-	26472758	K562	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-2.8250026732910327	[595]	[70]	-8	hSpCas9	negative selection	577963
44293143	44293166	21	-	26472758	K562	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.25230256920610494	[1743]	[1235]	-2	hSpCas9	negative selection	577964
44286030	44286053	21	-	26627737	DLD1	viability	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.473643592465292	[714]	[339,379,226]	5	hSpCas9	negative selection	816454
44286664	44286687	21	+	26627737	DLD1	viability	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.4442435550163536	[564]	[177,294,248]	4	hSpCas9	negative selection	816455
44286978	44287001	21	+	26627737	DLD1	viability	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-0.17830462758565757	[281]	[40,20,156]	-2	hSpCas9	negative selection	816456
44287570	44287593	21	+	26627737	DLD1	viability	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.446251817932229	[680]	[343,357,186]	4	hSpCas9	negative selection	816457
44288354	44288377	21	-	26627737	DLD1	viability	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.4917220259329974	[276]	[28,99,57]	-5	hSpCas9	negative selection	816458
44289653	44289676	21	-	26627737	DLD1	viability	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	2.062514994949973	[67]	[73,132,64]	9	hSpCas9	negative selection	816459
44286030	44286053	21	-	26627737	GBM cells	viability after 5 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.1947855206743565	[513]	[315,314]	3	hSpCas9	negative selection	898769
44286664	44286687	21	+	26627737	GBM cells	viability after 5 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.07224547777124757	[187]	[110,100]	1	hSpCas9	negative selection	898770
44286978	44287001	21	+	26627737	GBM cells	viability after 5 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-0.5705714084155348	[179]	[69,59]	-7	hSpCas9	negative selection	898771
44287570	44287593	21	+	26627737	GBM cells	viability after 5 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.27546653704186697	[526]	[244,221]	-4	hSpCas9	negative selection	898772
44288354	44288377	21	-	26627737	GBM cells	viability after 5 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.29222761246632256	[136]	[67,51]	-4	hSpCas9	negative selection	898773
44289653	44289676	21	-	26627737	GBM cells	viability after 5 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-0.8853574340588772	[61]	[17,17]	-8	hSpCas9	negative selection	898774
44286030	44286053	21	-	26627737	GBM cells	viability after 13 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.012922971935390937	[513]	[314,244]	0	hSpCas9	negative selection	981084
44286664	44286687	21	+	26627737	GBM cells	viability after 13 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.007201342935323429	[187]	[96,106]	0	hSpCas9	negative selection	981085
44286978	44287001	21	+	26627737	GBM cells	viability after 13 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-0.06353640410924555	[179]	[109,79]	0	hSpCas9	negative selection	981086
44287570	44287593	21	+	26627737	GBM cells	viability after 13 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.23487449399970484	[526]	[269,220]	-3	hSpCas9	negative selection	981087
44288354	44288377	21	-	26627737	GBM cells	viability after 13 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	0.08986457111595691	[136]	[93,66]	1	hSpCas9	negative selection	981088
44289653	44289676	21	-	26627737	GBM cells	viability after 13 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-0.520667645806506	[61]	[23,22]	-6	hSpCas9	negative selection	981089
44286030	44286053	21	-	26627737	GBM cells	viability after 21 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.2414651972383699	[513]	[338,321]	2	hSpCas9	negative selection	1063399
44286664	44286687	21	+	26627737	GBM cells	viability after 21 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.5903476741324335	[187]	[158,148]	6	hSpCas9	negative selection	1063400
44286978	44287001	21	+	26627737	GBM cells	viability after 21 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-0.9751562901401468	[179]	[43,54]	-7	hSpCas9	negative selection	1063401
44287570	44287593	21	+	26627737	GBM cells	viability after 21 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.4295034669008607	[526]	[233,192]	-4	hSpCas9	negative selection	1063402
44288354	44288377	21	-	26627737	GBM cells	viability after 21 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.012684353440255647	[136]	[78,68]	0	hSpCas9	negative selection	1063403
44289653	44289676	21	-	26627737	GBM cells	viability after 21 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	0.13202025086148472	[61]	[38,34]	1	hSpCas9	negative selection	1063404
44286030	44286053	21	-	26627737	RPE1	viability after 9 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.24220862560281287	[1867]	[613,791]	1	hSpCas9	negative selection	1145714
44286664	44286687	21	+	26627737	RPE1	viability after 9 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.20697558668566174	[1321]	[327,397]	-1	hSpCas9	negative selection	1145715
44286978	44287001	21	+	26627737	RPE1	viability after 9 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.8649644546771912	[334]	[135,261]	5	hSpCas9	negative selection	1145716
44287570	44287593	21	+	26627737	RPE1	viability after 9 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.6218513292426749	[1720]	[288,428]	-4	hSpCas9	negative selection	1145717
44288354	44288377	21	-	26627737	RPE1	viability after 9 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.9292358882614916	[442]	[50,100]	-6	hSpCas9	negative selection	1145718
44289653	44289676	21	-	26627737	RPE1	viability after 9 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	3.598423146160459	[33]	[155,93]	9	hSpCas9	negative selection	1145719
44286030	44286053	21	-	26627737	RPE1	viability after 12 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.14525090130427265	[1867]	[504,607]	1	hSpCas9	negative selection	1228029
44286664	44286687	21	+	26627737	RPE1	viability after 12 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.27848253510138243	[1321]	[371,208]	-2	hSpCas9	negative selection	1228030
44286978	44287001	21	+	26627737	RPE1	viability after 12 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.8405463309878995	[334]	[115,208]	5	hSpCas9	negative selection	1228031
44287570	44287593	21	+	26627737	RPE1	viability after 12 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.6202592135767909	[1720]	[276,325]	-4	hSpCas9	negative selection	1228032
44288354	44288377	21	-	26627737	RPE1	viability after 12 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.6352409719223727	[442]	[63,89]	-4	hSpCas9	negative selection	1228033
44289653	44289676	21	-	26627737	RPE1	viability after 12 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	3.312814928191324	[33]	[150,26]	9	hSpCas9	negative selection	1228034
44286030	44286053	21	-	26627737	RPE1	viability after 15 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.009617398192387716	[1867]	[473,573]	0	hSpCas9	negative selection	1310344
44286664	44286687	21	+	26627737	RPE1	viability after 15 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.12568283353881493	[1321]	[355,329]	-1	hSpCas9	negative selection	1310345
44286978	44287001	21	+	26627737	RPE1	viability after 15 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.8668307674918908	[334]	[154,189]	5	hSpCas9	negative selection	1310346
44287570	44287593	21	+	26627737	RPE1	viability after 15 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-1.2696851789188017	[1720]	[262,142]	-7	hSpCas9	negative selection	1310347
44288354	44288377	21	-	26627737	RPE1	viability after 15 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.7466136490371885	[442]	[35,111]	-5	hSpCas9	negative selection	1310348
44289653	44289676	21	-	26627737	RPE1	viability after 15 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	4.060349415434444	[33]	[218,103]	9	hSpCas9	negative selection	1310349
44286030	44286053	21	-	26627737	RPE1	viability after 18 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.08004767204105012	[1867]	[470,598]	0	hSpCas9	negative selection	1392659
44286664	44286687	21	+	26627737	RPE1	viability after 18 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.1670737478205292	[1321]	[295,340]	-1	hSpCas9	negative selection	1392660
44286978	44287001	21	+	26627737	RPE1	viability after 18 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.9744236104785104	[334]	[166,188]	6	hSpCas9	negative selection	1392661
44287570	44287593	21	+	26627737	RPE1	viability after 18 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.8738313969770899	[1720]	[280,223]	-5	hSpCas9	negative selection	1392662
44288354	44288377	21	-	26627737	RPE1	viability after 18 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-1.1900519167732022	[442]	[63,39]	-6	hSpCas9	negative selection	1392663
44289653	44289676	21	-	26627737	RPE1	viability after 18 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	4.365568888541851	[33]	[207,168]	9	hSpCas9	negative selection	1392664
44286030	44286053	21	-	26627737	HeLa	viability after 8 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.7288301506137634	[643]	[548,355,503]	6	hSpCas9	negative selection	1474974
44286664	44286687	21	+	26627737	HeLa	viability after 8 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.10825393225644542	[650]	[252,192,334]	-1	hSpCas9	negative selection	1474975
44286978	44287001	21	+	26627737	HeLa	viability after 8 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	1.8690708168064203	[122]	[159,93,315]	9	hSpCas9	negative selection	1474976
44287570	44287593	21	+	26627737	HeLa	viability after 8 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.16545506482313077	[793]	[408,456,306]	1	hSpCas9	negative selection	1474977
44288354	44288377	21	-	26627737	HeLa	viability after 8 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	0.06338273027275754	[269]	[144,161,69]	0	hSpCas9	negative selection	1474978
44289653	44289676	21	-	26627737	HeLa	viability after 8 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	2.183683879227628	[47]	[116,128,46]	9	hSpCas9	negative selection	1474979
44286030	44286053	21	-	26627737	HeLa	viability after 12 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.8532647714072635	[643]	[632,469,344]	6	hSpCas9	negative selection	1557289
44286664	44286687	21	+	26627737	HeLa	viability after 12 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.16771316938863823	[650]	[281,207,425]	1	hSpCas9	negative selection	1557290
44286978	44287001	21	+	26627737	HeLa	viability after 12 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	1.8127121423866086	[122]	[151,111,277]	9	hSpCas9	negative selection	1557291
44287570	44287593	21	+	26627737	HeLa	viability after 12 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.027475450018858316	[793]	[160,204,645]	0	hSpCas9	negative selection	1557292
44288354	44288377	21	-	26627737	HeLa	viability after 12 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.3518977939688629	[269]	[112,49,103]	-3	hSpCas9	negative selection	1557293
44289653	44289676	21	-	26627737	HeLa	viability after 12 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	2.179456940003465	[47]	[149,73,48]	9	hSpCas9	negative selection	1557294
44286030	44286053	21	-	26627737	HeLa	viability after 15 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.9627294874460234	[643]	[682,453,383]	7	hSpCas9	negative selection	1639604
44286664	44286687	21	+	26627737	HeLa	viability after 15 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.23643389624305255	[650]	[416,245,268]	2	hSpCas9	negative selection	1639605
44286978	44287001	21	+	26627737	HeLa	viability after 15 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	2.0257660625841094	[122]	[302,144,158]	9	hSpCas9	negative selection	1639606
44287570	44287593	21	+	26627737	HeLa	viability after 15 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.12417499535824972	[793]	[308,278,301]	-1	hSpCas9	negative selection	1639607
44288354	44288377	21	-	26627737	HeLa	viability after 15 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.5141317259344774	[269]	[66,26,141]	-4	hSpCas9	negative selection	1639608
44289653	44289676	21	-	26627737	HeLa	viability after 15 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-0.6967700770763994	[47]	[0,26,7]	-6	hSpCas9	negative selection	1639609
44286030	44286053	21	-	26627737	HeLa	viability after 18 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.996003568354651	[643]	[482,373,383]	7	hSpCas9	negative selection	1721919
44286664	44286687	21	+	26627737	HeLa	viability after 18 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.25683974561159806	[650]	[288,202,268]	2	hSpCas9	negative selection	1721920
44286978	44287001	21	+	26627737	HeLa	viability after 18 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	2.0780791871030027	[122]	[209,129,158]	9	hSpCas9	negative selection	1721921
44287570	44287593	21	+	26627737	HeLa	viability after 18 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.11754895178196523	[793]	[209,230,301]	-1	hSpCas9	negative selection	1721922
44288354	44288377	21	-	26627737	HeLa	viability after 18 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.5755547949108583	[269]	[38,21,141]	-5	hSpCas9	negative selection	1721923
44289653	44289676	21	-	26627737	HeLa	viability after 18 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-0.6940852188207574	[47]	[0,21,7]	-6	hSpCas9	negative selection	1721924
44286030	44286053	21	-	26627737	HCT116	viability after 6 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.03933741252978562	[1163]	[305,122]	0	hSpCas9	negative selection	1804234
44286664	44286687	21	+	26627737	HCT116	viability after 6 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	2.3167608762286758	[490]	[332,412]	9	hSpCas9	negative selection	1804235
44286978	44287001	21	+	26627737	HCT116	viability after 6 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-1.078051298936225	[301]	[26,19]	-6	hSpCas9	negative selection	1804236
44287570	44287593	21	+	26627737	HCT116	viability after 6 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.8083884060727662	[1371]	[155,499]	4	hSpCas9	negative selection	1804237
44288354	44288377	21	-	26627737	HCT116	viability after 6 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	2.1007916182947217	[175]	[21,171]	8	hSpCas9	negative selection	1804238
44289653	44289676	21	-	26627737	HCT116	viability after 6 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-3.138094664870037	[55]	[0,0]	-9	hSpCas9	negative selection	1804239
44286030	44286053	21	-	26627737	HCT116	viability after 8 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.41292474465354	[736]	[508,531,579]	4	hSpCas9	negative selection	1886549
44286664	44286687	21	+	26627737	HCT116	viability after 8 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.6223163168456785	[562]	[243,212,148]	-6	hSpCas9	negative selection	1886550
44286978	44287001	21	+	26627737	HCT116	viability after 8 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-1.3413509265720358	[239]	[43,24,86]	-9	hSpCas9	negative selection	1886551
44287570	44287593	21	+	26627737	HCT116	viability after 8 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.6560617038511911	[384]	[333,344,323]	6	hSpCas9	negative selection	1886552
44288354	44288377	21	-	26627737	HCT116	viability after 8 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	1.099898758267291	[80]	[131,88,66]	8	hSpCas9	negative selection	1886553
44289653	44289676	21	-	26627737	HCT116	viability after 8 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-0.8661991636767719	[102]	[21,19,50]	-8	hSpCas9	negative selection	1886554
44286030	44286053	21	-	26627737	HCT116	viability after 9 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.20320395942704195	[1163]	[225,461]	1	hSpCas9	negative selection	1968864
44286664	44286687	21	+	26627737	HCT116	viability after 9 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.81067459109756	[490]	[277,191]	6	hSpCas9	negative selection	1968865
44286978	44287001	21	+	26627737	HCT116	viability after 9 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	1.270979687507505	[301]	[164,217]	8	hSpCas9	negative selection	1968866
44287570	44287593	21	+	26627737	HCT116	viability after 9 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.15845345092506602	[1371]	[406,265]	-1	hSpCas9	negative selection	1968867
44288354	44288377	21	-	26627737	HCT116	viability after 9 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	0.06159367787006009	[175]	[81,22]	0	hSpCas9	negative selection	1968868
44289653	44289676	21	-	26627737	HCT116	viability after 9 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	1.8262908498861532	[55]	[109,7]	9	hSpCas9	negative selection	1968869
44286030	44286053	21	-	26627737	HCT116	viability after 12 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.2907568019397657	[736]	[433,643,350]	3	hSpCas9	negative selection	2051179
44286664	44286687	21	+	26627737	HCT116	viability after 12 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.5822030103854625	[562]	[192,185,213]	-6	hSpCas9	negative selection	2051180
44286978	44287001	21	+	26627737	HCT116	viability after 12 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.2941759970209797	[239]	[130,152,181]	3	hSpCas9	negative selection	2051181
44287570	44287593	21	+	26627737	HCT116	viability after 12 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.459788877389873	[384]	[251,355,230]	4	hSpCas9	negative selection	2051182
44288354	44288377	21	-	26627737	HCT116	viability after 12 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	0.02027486662044531	[80]	[46,35,45]	0	hSpCas9	negative selection	2051183
44289653	44289676	21	-	26627737	HCT116	viability after 12 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-0.5050690322459117	[102]	[5,27,82]	-5	hSpCas9	negative selection	2051184
44286030	44286053	21	-	26627737	HCT116	viability after 15 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.3018118473983369	[736]	[668,545,369]	3	hSpCas9	negative selection	2133494
44286664	44286687	21	+	26627737	HCT116	viability after 15 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.17426529654097112	[562]	[229,357,264]	-2	hSpCas9	negative selection	2133495
44286978	44287001	21	+	26627737	HCT116	viability after 15 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-0.23819421585407452	[239]	[84,170,90]	-2	hSpCas9	negative selection	2133496
44287570	44287593	21	+	26627737	HCT116	viability after 15 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	1.0124756736438616	[384]	[457,385,494]	8	hSpCas9	negative selection	2133497
44288354	44288377	21	-	26627737	HCT116	viability after 15 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	0.6147318721006263	[80]	[112,52,52]	5	hSpCas9	negative selection	2133498
44289653	44289676	21	-	26627737	HCT116	viability after 15 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-2.5651604015338654	[102]	[0,26,0]	-9	hSpCas9	negative selection	2133499
44286030	44286053	21	-	26627737	HCT116	viability after 18 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.4605874129615535	[736]	[368,667,418]	4	hSpCas9	negative selection	2215809
44286664	44286687	21	+	26627737	HCT116	viability after 18 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.06708412304978817	[562]	[399,232,222]	0	hSpCas9	negative selection	2215810
44286978	44287001	21	+	26627737	HCT116	viability after 18 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-0.972049353309547	[239]	[54,38,85]	-7	hSpCas9	negative selection	2215811
44287570	44287593	21	+	26627737	HCT116	viability after 18 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.5031998509418398	[384]	[309,239,241]	4	hSpCas9	negative selection	2215812
44288354	44288377	21	-	26627737	HCT116	viability after 18 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	0.9581524829498358	[80]	[145,57,22]	7	hSpCas9	negative selection	2215813
44289653	44289676	21	-	26627737	HCT116	viability after 18 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-1.913246540549663	[102]	[6,29,0]	-9	hSpCas9	negative selection	2215814
44286004	44286027	21	-	24336569	HL60	viability	AGCGCCGCGTCCGTCGCCATGGG	AIRE	ENSG00000160224	0.42442682910106083	[499]	[1419]	4	hSpCas9	negative selection	2247212
44286011	44286034	21	+	24336569	HL60	viability	CGACGGACGCGGCGCTACGCCGG	AIRE	ENSG00000160224	0.6291073987010797	[512]	[1678]	5	hSpCas9	negative selection	2247213
44286020	44286043	21	+	24336569	HL60	viability	CGGCGCTACGCCGGCTTCTGAGG	AIRE	ENSG00000160224	-0.6389458649279458	[38]	[52]	-5	hSpCas9	negative selection	2247214
44286030	44286053	21	-	24336569	HL60	viability	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.0060822887867588715	[782]	[1649]	0	hSpCas9	negative selection	2247215
44286042	44286065	21	+	24336569	HL60	viability	GCTGCACCGCACGGAGATCGCGG	AIRE	ENSG00000160224	-0.7570779632128228	[1641]	[2055]	-6	hSpCas9	negative selection	2247216
44286048	44286071	21	-	24336569	HL60	viability	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	-0.46355117810645363	[807]	[1239]	-4	hSpCas9	negative selection	2247217
44286068	44286091	21	-	24336569	HL60	viability	CAGTGGGAAGGCGCTGTCCACGG	AIRE	ENSG00000160224	0.3952891831363633	[428]	[1193]	3	hSpCas9	negative selection	2247218
44286080	44286103	21	-	24336569	HL60	viability	CAGCGCGTGCAGCAGTGGGAAGG	AIRE	ENSG00000160224	0.017981260546584776	[1064]	[2281]	0	hSpCas9	negative selection	2247219
44286085	44286108	21	-	24336569	HL60	viability	TCAGCCAGCGCGTGCAGCAGTGG	AIRE	ENSG00000160224	0.10157640060367434	[291]	[662]	1	hSpCas9	negative selection	2247220
44286096	44286119	21	+	24336569	HL60	viability	CGCGCTGGCTGACCACGACGTGG	AIRE	ENSG00000160224	-0.7953744585674368	[806]	[983]	-6	hSpCas9	negative selection	2247221
44286004	44286027	21	-	24336569	KBM7	viability	AGCGCCGCGTCCGTCGCCATGGG	AIRE	ENSG00000160224	0.7675600378932927	[526]	[2446]	7	hSpCas9	negative selection	2314389
44286011	44286034	21	+	24336569	KBM7	viability	CGACGGACGCGGCGCTACGCCGG	AIRE	ENSG00000160224	0.1821712259191116	[665]	[2060]	1	hSpCas9	negative selection	2314390
44286020	44286043	21	+	24336569	KBM7	viability	CGGCGCTACGCCGGCTTCTGAGG	AIRE	ENSG00000160224	-1.187051646325663	[95]	[114]	-7	hSpCas9	negative selection	2314391
44286030	44286053	21	-	24336569	KBM7	viability	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.47380120232193396	[693]	[1362]	-4	hSpCas9	negative selection	2314392
44286042	44286065	21	+	24336569	KBM7	viability	GCTGCACCGCACGGAGATCGCGG	AIRE	ENSG00000160224	1.114710835870617	[480]	[2840]	8	hSpCas9	negative selection	2314393
44286048	44286071	21	-	24336569	KBM7	viability	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	0.23810941845488764	[672]	[2164]	2	hSpCas9	negative selection	2314394
44286068	44286091	21	-	24336569	KBM7	viability	CAGTGGGAAGGCGCTGTCCACGG	AIRE	ENSG00000160224	0.14174849673367562	[659]	[1985]	1	hSpCas9	negative selection	2314395
44286080	44286103	21	-	24336569	KBM7	viability	CAGCGCGTGCAGCAGTGGGAAGG	AIRE	ENSG00000160224	0.22456994469464486	[716]	[2284]	2	hSpCas9	negative selection	2314396
44286085	44286108	21	-	24336569	KBM7	viability	TCAGCCAGCGCGTGCAGCAGTGG	AIRE	ENSG00000160224	1.4055794151218464	[123]	[895]	9	hSpCas9	negative selection	2314397
44286096	44286119	21	+	24336569	KBM7	viability	CGCGCTGGCTGACCACGACGTGG	AIRE	ENSG00000160224	0.689765536265788	[412]	[1816]	6	hSpCas9	negative selection	2314398
44286085	44286108	21	-	27260157	DLD1	viability	TCAGCCAGCGCGTGCAGCAGTGG	AIRE	ENSG00000160224	-0.10777539485433	[]	[]	-1	hSpCas9	negative selection	2573990
44286042	44286065	21	+	27260157	DLD1	viability	GCTGCACCGCACGGAGATCGCGG	AIRE	ENSG00000160224	0.233429815593213	[]	[]	4	hSpCas9	negative selection	2575445
44286045	44286068	21	+	27260157	DLD1	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.387395286078134	[]	[]	4	hSpCas9	negative selection	2576549
44286664	44286687	21	+	27260157	DLD1	viability	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	1.86414468920388	[]	[]	9	hSpCas9	negative selection	2577558
44286030	44286053	21	-	27260157	DLD1	viability	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.524040713977426	[]	[]	8	hSpCas9	negative selection	2579606
44286682	44286705	21	-	27260157	DLD1	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.418442085178577	[]	[]	7	hSpCas9	negative selection	2582051
44286096	44286119	21	+	27260157	DLD1	viability	CGCGCTGGCTGACCACGACGTGG	AIRE	ENSG00000160224	0.989137039431471	[]	[]	9	hSpCas9	negative selection	2582135
44287024	44287047	21	-	27260157	DLD1	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.209593930571829	[]	[]	-1	hSpCas9	negative selection	2584627
44286080	44286103	21	-	27260157	DLD1	viability	CAGCGCGTGCAGCAGTGGGAAGG	AIRE	ENSG00000160224	0.729881676281033	[]	[]	8	hSpCas9	negative selection	2604683
44286048	44286071	21	-	27260157	DLD1	viability	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	0.333796276152366	[]	[]	4	hSpCas9	negative selection	2607604
44286081	44286104	21	+	27260157	DLD1	viability	CTTCCCACTGCTGCACGCGCTGG	AIRE	ENSG00000160224	-0.505069732214916	[]	[]	-4	hSpCas9	negative selection	2608359
44286068	44286091	21	-	27260157	DLD1	viability	CAGTGGGAAGGCGCTGTCCACGG	AIRE	ENSG00000160224	0.157016918647283	[]	[]	3	hSpCas9	negative selection	2609012
44289663	44289686	21	-	27260157	DLD1	viability	GCCAACCTGGATGCACTTCTTGG	AIRE	ENSG00000160224	0.192374151597966	[]	[]	3	hSpCas9	negative selection	2609492
44286004	44286027	21	-	27260157	DLD1	viability	AGCGCCGCGTCCGTCGCCATGGG	AIRE	ENSG00000160224	-1.30569073450346	[]	[]	-7	hSpCas9	negative selection	2615546
44286674	44286697	21	+	27260157	DLD1	viability	GACTACAACCTGGAGCGCTATGG	AIRE	ENSG00000160224	0.924310531201032	[]	[]	9	hSpCas9	negative selection	2621520
44286020	44286043	21	+	27260157	DLD1	viability	CGGCGCTACGCCGGCTTCTGAGG	AIRE	ENSG00000160224	-0.219865612842595	[]	[]	-2	hSpCas9	negative selection	2622465
44289757	44289780	21	-	27260157	DLD1	viability	TGGCTCGAACCAGAGGCTTCGGG	AIRE	ENSG00000160224	0.211623427643719	[]	[]	3	hSpCas9	negative selection	2644571
44286011	44286034	21	+	27260157	DLD1	viability	CGACGGACGCGGCGCTACGCCGG	AIRE	ENSG00000160224	-0.588536680647219	[]	[]	-5	hSpCas9	negative selection	2649214
44286085	44286108	21	-	27260157	HT1080	viability	TCAGCCAGCGCGTGCAGCAGTGG	AIRE	ENSG00000160224	-0.169317797791654	[]	[]	0	hSpCas9	negative selection	2650120
44286042	44286065	21	+	27260157	HT1080	viability	GCTGCACCGCACGGAGATCGCGG	AIRE	ENSG00000160224	0.613046839148027	[]	[]	5	hSpCas9	negative selection	2651575
44286045	44286068	21	+	27260157	HT1080	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-0.0747801983060837	[]	[]	0	hSpCas9	negative selection	2652679
44286664	44286687	21	+	27260157	HT1080	viability	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.344634153310431	[]	[]	-7	hSpCas9	negative selection	2653688
44286030	44286053	21	-	27260157	HT1080	viability	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.350074740770404	[]	[]	3	hSpCas9	negative selection	2655736
44286682	44286705	21	-	27260157	HT1080	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.730973948630858	[]	[]	-8	hSpCas9	negative selection	2658181
44286096	44286119	21	+	27260157	HT1080	viability	CGCGCTGGCTGACCACGACGTGG	AIRE	ENSG00000160224	1.00345845167113	[]	[]	8	hSpCas9	negative selection	2658265
44287024	44287047	21	-	27260157	HT1080	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.593357026302397	[]	[]	5	hSpCas9	negative selection	2660757
44286080	44286103	21	-	27260157	HT1080	viability	CAGCGCGTGCAGCAGTGGGAAGG	AIRE	ENSG00000160224	-0.379450950775577	[]	[]	-7	hSpCas9	negative selection	2680813
44286048	44286071	21	-	27260157	HT1080	viability	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	0.680975768269691	[]	[]	6	hSpCas9	negative selection	2683734
44286081	44286104	21	+	27260157	HT1080	viability	CTTCCCACTGCTGCACGCGCTGG	AIRE	ENSG00000160224	-0.290395838282722	[]	[]	-7	hSpCas9	negative selection	2684489
44286068	44286091	21	-	27260157	HT1080	viability	CAGTGGGAAGGCGCTGTCCACGG	AIRE	ENSG00000160224	-0.165757545934422	[]	[]	0	hSpCas9	negative selection	2685142
44289663	44289686	21	-	27260157	HT1080	viability	GCCAACCTGGATGCACTTCTTGG	AIRE	ENSG00000160224	0.708370735920507	[]	[]	6	hSpCas9	negative selection	2685622
44286004	44286027	21	-	27260157	HT1080	viability	AGCGCCGCGTCCGTCGCCATGGG	AIRE	ENSG00000160224	-0.346412737155269	[]	[]	-7	hSpCas9	negative selection	2691676
44286674	44286697	21	+	27260157	HT1080	viability	GACTACAACCTGGAGCGCTATGG	AIRE	ENSG00000160224	-0.173581225392106	[]	[]	0	hSpCas9	negative selection	2697650
44286020	44286043	21	+	27260157	HT1080	viability	CGGCGCTACGCCGGCTTCTGAGG	AIRE	ENSG00000160224	-0.633492059668416	[]	[]	-8	hSpCas9	negative selection	2698595
44289757	44289780	21	-	27260157	HT1080	viability	TGGCTCGAACCAGAGGCTTCGGG	AIRE	ENSG00000160224	1.24345622989698	[]	[]	8	hSpCas9	negative selection	2720701
44286011	44286034	21	+	27260157	HT1080	viability	CGACGGACGCGGCGCTACGCCGG	AIRE	ENSG00000160224	-0.452096324703989	[]	[]	-7	hSpCas9	negative selection	2725344
44286085	44286108	21	-	27260157	MKN45	viability	TCAGCCAGCGCGTGCAGCAGTGG	AIRE	ENSG00000160224	0.746256428998086	[]	[]	7	hSpCas9	negative selection	2726250
44286042	44286065	21	+	27260157	MKN45	viability	GCTGCACCGCACGGAGATCGCGG	AIRE	ENSG00000160224	1.04752292194268	[]	[]	8	hSpCas9	negative selection	2727705
44286045	44286068	21	+	27260157	MKN45	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.142987106269253	[]	[]	5	hSpCas9	negative selection	2728809
44286664	44286687	21	+	27260157	MKN45	viability	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.996188670349701	[]	[]	8	hSpCas9	negative selection	2729818
44286030	44286053	21	-	27260157	MKN45	viability	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.13736704967054	[]	[]	5	hSpCas9	negative selection	2731866
44286682	44286705	21	-	27260157	MKN45	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.479161241977706	[]	[]	6	hSpCas9	negative selection	2734311
44286096	44286119	21	+	27260157	MKN45	viability	CGCGCTGGCTGACCACGACGTGG	AIRE	ENSG00000160224	1.61915482555859	[]	[]	9	hSpCas9	negative selection	2734395
44287024	44287047	21	-	27260157	MKN45	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.122240837657434	[]	[]	4	hSpCas9	negative selection	2736887
44286080	44286103	21	-	27260157	MKN45	viability	CAGCGCGTGCAGCAGTGGGAAGG	AIRE	ENSG00000160224	-0.275970908440915	[]	[]	-1	hSpCas9	negative selection	2756943
44286048	44286071	21	-	27260157	MKN45	viability	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	-0.409772785644451	[]	[]	-6	hSpCas9	negative selection	2759864
44286081	44286104	21	+	27260157	MKN45	viability	CTTCCCACTGCTGCACGCGCTGG	AIRE	ENSG00000160224	-0.6179724790599	[]	[]	-6	hSpCas9	negative selection	2760619
44286068	44286091	21	-	27260157	MKN45	viability	CAGTGGGAAGGCGCTGTCCACGG	AIRE	ENSG00000160224	-0.36758042247938	[]	[]	-1	hSpCas9	negative selection	2761272
44289663	44289686	21	-	27260157	MKN45	viability	GCCAACCTGGATGCACTTCTTGG	AIRE	ENSG00000160224	1.13093489756974	[]	[]	8	hSpCas9	negative selection	2761752
44286004	44286027	21	-	27260157	MKN45	viability	AGCGCCGCGTCCGTCGCCATGGG	AIRE	ENSG00000160224	-0.428889097670155	[]	[]	-6	hSpCas9	negative selection	2767806
44286674	44286697	21	+	27260157	MKN45	viability	GACTACAACCTGGAGCGCTATGG	AIRE	ENSG00000160224	0.9268916099305	[]	[]	8	hSpCas9	negative selection	2773780
44286020	44286043	21	+	27260157	MKN45	viability	CGGCGCTACGCCGGCTTCTGAGG	AIRE	ENSG00000160224	0.485747713907513	[]	[]	6	hSpCas9	negative selection	2774725
44289757	44289780	21	-	27260157	MKN45	viability	TGGCTCGAACCAGAGGCTTCGGG	AIRE	ENSG00000160224	0.803966724076602	[]	[]	7	hSpCas9	negative selection	2796831
44286011	44286034	21	+	27260157	MKN45	viability	CGACGGACGCGGCGCTACGCCGG	AIRE	ENSG00000160224	-0.403007662450552	[]	[]	-1	hSpCas9	negative selection	2801474
44286085	44286108	21	-	27260157	RKO	viability	TCAGCCAGCGCGTGCAGCAGTGG	AIRE	ENSG00000160224	-0.133179072965499	[]	[]	0	hSpCas9	negative selection	2802380
44286042	44286065	21	+	27260157	RKO	viability	GCTGCACCGCACGGAGATCGCGG	AIRE	ENSG00000160224	0.83901594658714	[]	[]	8	hSpCas9	negative selection	2803835
44286045	44286068	21	+	27260157	RKO	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.00876952210644497	[]	[]	0	hSpCas9	negative selection	2804939
44286664	44286687	21	+	27260157	RKO	viability	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	1.32310004339543	[]	[]	9	hSpCas9	negative selection	2805948
44286030	44286053	21	-	27260157	RKO	viability	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.84236238299658	[]	[]	-7	hSpCas9	negative selection	2807996
44286682	44286705	21	-	27260157	RKO	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.0699690750643016	[]	[]	0	hSpCas9	negative selection	2810441
44286096	44286119	21	+	27260157	RKO	viability	CGCGCTGGCTGACCACGACGTGG	AIRE	ENSG00000160224	0.941488594054224	[]	[]	8	hSpCas9	negative selection	2810525
44287024	44287047	21	-	27260157	RKO	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.711224510855885	[]	[]	8	hSpCas9	negative selection	2813017
44286080	44286103	21	-	27260157	RKO	viability	CAGCGCGTGCAGCAGTGGGAAGG	AIRE	ENSG00000160224	0.10665547214914	[]	[]	0	hSpCas9	negative selection	2833073
44286048	44286071	21	-	27260157	RKO	viability	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	0.742281392524116	[]	[]	8	hSpCas9	negative selection	2835994
44286081	44286104	21	+	27260157	RKO	viability	CTTCCCACTGCTGCACGCGCTGG	AIRE	ENSG00000160224	-0.122327486965917	[]	[]	0	hSpCas9	negative selection	2836749
44286068	44286091	21	-	27260157	RKO	viability	CAGTGGGAAGGCGCTGTCCACGG	AIRE	ENSG00000160224	0.544949237563414	[]	[]	3	hSpCas9	negative selection	2837402
44289663	44289686	21	-	27260157	RKO	viability	GCCAACCTGGATGCACTTCTTGG	AIRE	ENSG00000160224	1.21580734170117	[]	[]	9	hSpCas9	negative selection	2837882
44286004	44286027	21	-	27260157	RKO	viability	AGCGCCGCGTCCGTCGCCATGGG	AIRE	ENSG00000160224	1.17060409986457	[]	[]	9	hSpCas9	negative selection	2843936
44286674	44286697	21	+	27260157	RKO	viability	GACTACAACCTGGAGCGCTATGG	AIRE	ENSG00000160224	0.574724205631672	[]	[]	3	hSpCas9	negative selection	2849910
44286020	44286043	21	+	27260157	RKO	viability	CGGCGCTACGCCGGCTTCTGAGG	AIRE	ENSG00000160224	0.905532289381464	[]	[]	8	hSpCas9	negative selection	2850855
44289757	44289780	21	-	27260157	RKO	viability	TGGCTCGAACCAGAGGCTTCGGG	AIRE	ENSG00000160224	0.677776789435881	[]	[]	7	hSpCas9	negative selection	2872961
44286011	44286034	21	+	27260157	RKO	viability	CGACGGACGCGGCGCTACGCCGG	AIRE	ENSG00000160224	-0.425929008524097	[]	[]	-6	hSpCas9	negative selection	2877604
44286085	44286108	21	-	27260157	SF268	viability	TCAGCCAGCGCGTGCAGCAGTGG	AIRE	ENSG00000160224	0.269566086618596	[]	[]	4	hSpCas9	negative selection	2878510
44286042	44286065	21	+	27260157	SF268	viability	GCTGCACCGCACGGAGATCGCGG	AIRE	ENSG00000160224	0.220545458285308	[]	[]	3	hSpCas9	negative selection	2879965
44286045	44286068	21	+	27260157	SF268	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.511130498969071	[]	[]	7	hSpCas9	negative selection	2881069
44286664	44286687	21	+	27260157	SF268	viability	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.31718273337887	[]	[]	4	hSpCas9	negative selection	2882078
44286030	44286053	21	-	27260157	SF268	viability	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.155011547271006	[]	[]	0	hSpCas9	negative selection	2884126
44286682	44286705	21	-	27260157	SF268	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.124022349280075	[]	[]	0	hSpCas9	negative selection	2886571
44286096	44286119	21	+	27260157	SF268	viability	CGCGCTGGCTGACCACGACGTGG	AIRE	ENSG00000160224	0.219791877039006	[]	[]	3	hSpCas9	negative selection	2886655
44287024	44287047	21	-	27260157	SF268	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.683598882157376	[]	[]	8	hSpCas9	negative selection	2889147
44286080	44286103	21	-	27260157	SF268	viability	CAGCGCGTGCAGCAGTGGGAAGG	AIRE	ENSG00000160224	0.306909847405773	[]	[]	4	hSpCas9	negative selection	2909203
44286048	44286071	21	-	27260157	SF268	viability	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	0.241149438057336	[]	[]	3	hSpCas9	negative selection	2912124
44286081	44286104	21	+	27260157	SF268	viability	CTTCCCACTGCTGCACGCGCTGG	AIRE	ENSG00000160224	-0.263400946693793	[]	[]	-2	hSpCas9	negative selection	2912879
44286068	44286091	21	-	27260157	SF268	viability	CAGTGGGAAGGCGCTGTCCACGG	AIRE	ENSG00000160224	0.0823567824159127	[]	[]	0	hSpCas9	negative selection	2913532
44289663	44289686	21	-	27260157	SF268	viability	GCCAACCTGGATGCACTTCTTGG	AIRE	ENSG00000160224	1.13190004015756	[]	[]	9	hSpCas9	negative selection	2914012
44286004	44286027	21	-	27260157	SF268	viability	AGCGCCGCGTCCGTCGCCATGGG	AIRE	ENSG00000160224	-0.494615979672921	[]	[]	-4	hSpCas9	negative selection	2920066
44286674	44286697	21	+	27260157	SF268	viability	GACTACAACCTGGAGCGCTATGG	AIRE	ENSG00000160224	0.69446420887156	[]	[]	8	hSpCas9	negative selection	2926040
44286020	44286043	21	+	27260157	SF268	viability	CGGCGCTACGCCGGCTTCTGAGG	AIRE	ENSG00000160224	-0.376518208589047	[]	[]	-3	hSpCas9	negative selection	2926985
44289757	44289780	21	-	27260157	SF268	viability	TGGCTCGAACCAGAGGCTTCGGG	AIRE	ENSG00000160224	1.31689320463188	[]	[]	9	hSpCas9	negative selection	2949091
44286011	44286034	21	+	27260157	SF268	viability	CGACGGACGCGGCGCTACGCCGG	AIRE	ENSG00000160224	1.13676676548747	[]	[]	9	hSpCas9	negative selection	2953734
44287098	44287121	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGCAGCCCTGACTCCAAGGGG	AIRE	ENSG00000160224	-0.019153161270373698	[4,4]	[4,3]	0	hSpCas9	positive selection	2969609
44286048	44286071	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	-0.2311948118198437	[2,2]	[2,0]	-3	hSpCas9	positive selection	2969610
44286564	44286587	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCATCTGAAGGAAAAGGAGGG	AIRE	ENSG00000160224	-0.502857637236931	[4,3]	[2,1]	-6	hSpCas9	positive selection	2969611
44286046	44286069	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.41032372788423677	[3,2]	[3,3]	8	hSpCas9	positive selection	2969612
44287098	44287121	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGCAGCCCTGACTCCAAGGGG	AIRE	ENSG00000160224	0.36046764493932154	[4,4]	[4,3]	6	hSpCas9	positive selection	3037467
44286048	44286071	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	-0.5741415245686676	[2,2]	[2,0]	-7	hSpCas9	positive selection	3037468
44286564	44286587	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCATCTGAAGGAAAAGGAGGG	AIRE	ENSG00000160224	-0.11483952376738073	[4,4]	[2,2]	-2	hSpCas9	positive selection	3037469
44286046	44286069	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-0.5476087176098837	[3,3]	[2,0]	-7	hSpCas9	positive selection	3037470
44286678	44286701		+	24336571	A375	resistance to PLX after 7 days	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.1084415247466437	[4,8]	[7,6]	3	hSpCas9	positive selection	3110931
44286682	44286705		-	24336571	A375	resistance to PLX after 7 days	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.22130382572969617	[10,11]	[7,10]	-6	hSpCas9	positive selection	3110942
44287024	44287047		-	24336571	A375	resistance to PLX after 7 days	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.37534072259023576	[7,7]	[9,11]	8	hSpCas9	positive selection	3110952
44286678	44286701		+	24336571	A375	resistance to PLX after 14 days	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.5884073090578268	[7,10]	[2,1]	-7	hSpCas9	positive selection	3168724
44286682	44286705		-	24336571	A375	resistance to PLX after 14 days	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.07754772870720003	[13,8]	[3,4]	-1	hSpCas9	positive selection	3168735
44287024	44287047		-	24336571	A375	resistance to PLX after 14 days	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	1.0498155175913606	[8,9]	[8,8]	8	hSpCas9	positive selection	3168745
44286678	44286701		+	24336571	A375	viability after 7 days	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.04144567543912547	[7]	[4,8]	0	hSpCas9	negative selection	3226517
44286682	44286705		-	24336571	A375	viability after 7 days	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.22959883603585626	[9]	[10,11]	3	hSpCas9	negative selection	3226528
44287024	44287047		-	24336571	A375	viability after 7 days	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.23950320668557978	[6]	[7,7]	3	hSpCas9	negative selection	3226538
44286678	44286701		+	24336571	A375	viability after 14 days	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.32760343916421114	[7]	[7,10]	4	hSpCas9	negative selection	3284310
44286682	44286705		-	24336571	A375	viability after 14 days	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.3025653775483036	[9]	[13,8]	4	hSpCas9	negative selection	3284321
44287024	44287047		-	24336571	A375	viability after 14 days	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.4622745611941972	[6]	[8,9]	6	hSpCas9	negative selection	3284331
44287024	44287047	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	1.3033326976632984	[90,94]	[0,1]	5	hSpCas9	positive selection	3336067
44287579	44287602	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	3.138407751320049	[70,32]	[0,4]	8	hSpCas9	positive selection	3336068
44286682	44286705	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.7247729257475705	[103,80]	[0,0]	3	hSpCas9	positive selection	3336069
44286678	44286701	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	1.1698633701954957	[67,67]	[0,0]	5	hSpCas9	positive selection	3355315
44288384	44288407	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	1.3265888738829488	[60,60]	[0,0]	6	hSpCas9	positive selection	3355316
44287009	44287032	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	2.3031299010589596	[30,30]	[0,0]	8	hSpCas9	positive selection	3355317
44287097	44287120	21	+	26780180	HT29	viability (Avana library 4 designs)	CCAGCAGCCCTGACTCCAAGGGG	AIRE	ENSG00000160224	-0.16362386687932	[]	[]	-3	hSpCas9	negative selection	3405677
44286048	44286071	21	-	26780180	HT29	viability (Avana library 4 designs)	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	0.729772258660401	[]	[]	3	hSpCas9	negative selection	3405678
44286563	44286586	21	+	26780180	HT29	viability (Avana library 4 designs)	CTTCATCTGAAGGAAAAGGAGGG	AIRE	ENSG00000160224	0.386920940235125	[]	[]	1	hSpCas9	negative selection	3405679
44286045	44286068	21	+	26780180	HT29	viability (Avana library 4 designs)	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	1.10547311629883	[]	[]	4	hSpCas9	negative selection	3405680
44286563	44286586	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCATCTGAAGGAAAAGGAGGG	AIRE	ENSG00000160224	-3.99151781231746	[]	[]	-4	hSpCas9	negative selection	3477822
44286048	44286071	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	5.1939642478671	[]	[]	8	hSpCas9	negative selection	3477823
44287097	44287120	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCAGCCCTGACTCCAAGGGG	AIRE	ENSG00000160224	2.0369008872106	[]	[]	3	hSpCas9	negative selection	3477824
44286045	44286068	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-0.828901030912864	[]	[]	-1	hSpCas9	negative selection	3477825
44286640	44286663	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCCATCCTGGACTTCTGGAGGG	AIRE	ENSG00000160224	2.62646370664048	[]	[]	4	hSpCas9	negative selection	3477826
44286033	44286056	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCTGAGGCTGCACCGCACGG	AIRE	ENSG00000160224	4.56530700528108	[]	[]	7	hSpCas9	negative selection	3477827
44286563	44286586	21	+	26780180	A375	viability (Avana lentiGuide)	CTTCATCTGAAGGAAAAGGAGGG	AIRE	ENSG00000160224	-2.45026062173095	[]	[]	-4	hSpCas9	negative selection	3586481
44286048	44286071	21	-	26780180	A375	viability (Avana lentiGuide)	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	-3.92881513667047	[]	[]	-6	hSpCas9	negative selection	3586482
44287097	44287120	21	+	26780180	A375	viability (Avana lentiGuide)	CCAGCAGCCCTGACTCCAAGGGG	AIRE	ENSG00000160224	-1.00090004331744	[]	[]	-1	hSpCas9	negative selection	3586483
44286045	44286068	21	+	26780180	A375	viability (Avana lentiGuide)	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	10.1689170529261	[]	[]	7	hSpCas9	negative selection	3586484
44286640	44286663	21	+	26780180	A375	viability (Avana lentiGuide)	AGCCATCCTGGACTTCTGGAGGG	AIRE	ENSG00000160224	-4.3153564830244	[]	[]	-7	hSpCas9	negative selection	3586485
44286033	44286056	21	+	26780180	A375	viability (Avana lentiGuide)	GCTTCTGAGGCTGCACCGCACGG	AIRE	ENSG00000160224	-1.52975040632372	[]	[]	-2	hSpCas9	negative selection	3586486
44286563	44286586	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCATCTGAAGGAAAAGGAGGG	AIRE	ENSG00000160224	-0.7836567924499235	[5]	[1,3]	-8	hSpCas9	positive selection	3695140
44286048	44286071	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	0.2767856704174278	[4]	[4,4]	7	hSpCas9	positive selection	3695141
44287097	44287120	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCAGCCCTGACTCCAAGGGG	AIRE	ENSG00000160224	-0.338893268450716	[5]	[4,2]	-5	hSpCas9	positive selection	3695142
44286045	44286068	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.25928145674686776	[4]	[4,5]	7	hSpCas9	positive selection	3695143
44286640	44286663	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCCATCCTGGACTTCTGGAGGG	AIRE	ENSG00000160224	0.25234788818076914	[5]	[6,5]	7	hSpCas9	positive selection	3695144
44286033	44286056	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCTGAGGCTGCACCGCACGG	AIRE	ENSG00000160224	0.3767405133507423	[4]	[6,5]	9	hSpCas9	positive selection	3695145
44286563	44286586	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCATCTGAAGGAAAAGGAGGG	AIRE	ENSG00000160224	0.14470933063503144	[5]	[4,5]	3	hSpCas9	positive selection	3803747
44286048	44286071	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGCCACCGCGATCTCCGTGCGG	AIRE	ENSG00000160224	-0.2579858815850918	[5]	[3,2]	-4	hSpCas9	positive selection	3803748
44287097	44287120	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCAGCCCTGACTCCAAGGGG	AIRE	ENSG00000160224	0.24086036118503565	[6]	[6,6]	6	hSpCas9	positive selection	3803749
44286045	44286068	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.019967599293789176	[4]	[3,4]	0	hSpCas9	positive selection	3803750
44286640	44286663	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCCATCCTGGACTTCTGGAGGG	AIRE	ENSG00000160224	0.18122315979372813	[5]	[5,4]	4	hSpCas9	positive selection	3803751
44286033	44286056	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCTGAGGCTGCACCGCACGG	AIRE	ENSG00000160224	0.05614985984362833	[5]	[5,3]	1	hSpCas9	positive selection	3803752
44286678	44286701	21	+	26780180	A375	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	1.0805745132763	[]	[]	5	hSpCas9	negative selection	3912148
44287579	44287602	21	-	26780180	A375	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.781986521636513	[]	[]	3	hSpCas9	negative selection	3912149
44288384	44288407	21	-	26780180	A375	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.849461436637263	[]	[]	3	hSpCas9	negative selection	3912150
44287009	44287032	21	+	26780180	A375	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.67396093792806	[]	[]	2	hSpCas9	negative selection	3912151
44286682	44286705	21	-	26780180	A375	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.954860980552172	[]	[]	4	hSpCas9	negative selection	3912152
44287024	44287047	21	-	26780180	A375	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	1.40809543960132	[]	[]	7	hSpCas9	negative selection	3912153
44286678	44286701	21	+	26780180	HT29	viability (GeCKOv2 library)	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	1.20864202495225	[]	[]	6	hSpCas9	negative selection	4020114
44287579	44287602	21	-	26780180	HT29	viability (GeCKOv2 library)	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.679199076036367	[]	[]	2	hSpCas9	negative selection	4020115
44288384	44288407	21	-	26780180	HT29	viability (GeCKOv2 library)	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.792339764440175	[]	[]	3	hSpCas9	negative selection	4020116
44287009	44287032	21	+	26780180	HT29	viability (GeCKOv2 library)	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.938370158696558	[]	[]	4	hSpCas9	negative selection	4020117
44286682	44286705	21	-	26780180	HT29	viability (GeCKOv2 library)	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	1.32197218454698	[]	[]	6	hSpCas9	negative selection	4020118
44287024	44287047	21	-	26780180	HT29	viability (GeCKOv2 library)	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	1.91375569293951	[]	[]	9	hSpCas9	negative selection	4020119
44286678	44286701	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.42319135109844286	[3]	[1,1]	-8	hSpCas9	positive selection	4133509
44286682	44286705	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.037608146076669485	[3]	[1,2]	1	hSpCas9	positive selection	4133520
44287024	44287047	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.24512631060187312	[4]	[3,3]	6	hSpCas9	positive selection	4133531
44286678	44286701	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	1.0182899822009324	[3]	[1,1,0,4]	7	hSpCas9	positive selection	4197531
44286682	44286705	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.30405983568725686	[2]	[1,0,5,0]	2	hSpCas9	positive selection	4197542
44287024	44287047	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.03558294170773785	[3]	[1,2,1,0]	0	hSpCas9	positive selection	4197553
44287024	44287047	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.361289879365586	[2]	[2,0]	-6	hSpCas9	positive selection	4255070
44287579	44287602	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	-0.08589926077255361	[1]	[1,0]	-2	hSpCas9	positive selection	4255071
44286682	44286705	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.3878892927568205	[2]	[2,2]	7	hSpCas9	positive selection	4255072
44286678	44286701	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.3761594383243582	[2]	[1,0]	-7	hSpCas9	positive selection	4319352
44288384	44288407	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.06517582718749293	[1]	[1,0]	1	hSpCas9	positive selection	4319353
44287009	44287032	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.06895996633053236	[1]	[0,0]	-1	hSpCas9	positive selection	4319354
44286121	44286143	21	+	27760321	OCIAML3	viability	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.44784647098047203	[358,268]	[355,300]	5	hSpCas9	negative selection	4377011
44287026	44287048	21	-	27760321	OCIAML3	viability	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.3281454479108025	[623,515]	[445,701]	4	hSpCas9	negative selection	4377012
44287579	44287601	21	-	27760321	OCIAML3	viability	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	-0.3103838606558653	[804,746]	[436,557]	-3	hSpCas9	negative selection	4377013
44289676	44289698	21	-	27760321	OCIAML3	viability	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.893627850481089	[725,597]	[801,1159]	9	hSpCas9	negative selection	4377014
44289762	44289784	21	+	27760321	OCIAML3	viability	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.6608284395926389	[661,569]	[551,1029]	7	hSpCas9	negative selection	4377015
44286121	44286143	21	+	27760321	OCIAML2	viability	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.25301712586199465	[358,268]	[237,381]	3	hSpCas9	negative selection	4460474
44287026	44287048	21	-	27760321	OCIAML2	viability	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.34462798328252403	[623,515]	[493,699]	5	hSpCas9	negative selection	4460475
44287579	44287601	21	-	27760321	OCIAML2	viability	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.08911892232394725	[804,746]	[619,730]	1	hSpCas9	negative selection	4460476
44289676	44289698	21	-	27760321	OCIAML2	viability	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.0076035402122642815	[725,597]	[493,590]	0	hSpCas9	negative selection	4460477
44289762	44289784	21	+	27760321	OCIAML2	viability	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.16795521950231024	[661,569]	[458,688]	2	hSpCas9	negative selection	4460478
44286121	44286143	21	+	27760321	MV411	viability	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	1.3440166209978268	[358,268]	[706,242]	8	hSpCas9	negative selection	4543937
44287026	44287048	21	-	27760321	MV411	viability	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.35271381205104585	[623,515]	[432,545]	2	hSpCas9	negative selection	4543938
44287579	44287601	21	-	27760321	MV411	viability	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.04295483219609286	[804,746]	[374,756]	0	hSpCas9	negative selection	4543939
44289676	44289698	21	-	27760321	MV411	viability	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.07925636104652034	[725,597]	[432,498]	0	hSpCas9	negative selection	4543940
44289762	44289784	21	+	27760321	MV411	viability	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.8805163869995873	[661,569]	[563,1019]	6	hSpCas9	negative selection	4543941
44286121	44286143	21	+	27760321	HL60	viability	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.008813541142922765	[358,268]	[251,259]	0	hSpCas9	negative selection	4627400
44287026	44287048	21	-	27760321	HL60	viability	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	-0.24882733133938062	[623,515]	[442,333]	-3	hSpCas9	negative selection	4627401
44287579	44287601	21	-	27760321	HL60	viability	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	-0.5647228547651386	[804,746]	[433,422]	-6	hSpCas9	negative selection	4627402
44289676	44289698	21	-	27760321	HL60	viability	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.12132686495833511	[725,597]	[617,550]	1	hSpCas9	negative selection	4627403
44289762	44289784	21	+	27760321	HL60	viability	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.18177890846096173	[661,569]	[606,528]	2	hSpCas9	negative selection	4627404
44286121	44286143	21	+	27760321	HT1080	viability	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	2.0324788396361013	[268,209]	[291,497]	9	hSpCas9	negative selection	4710863
44287026	44287048	21	-	27760321	HT1080	viability	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.13243248119712597	[515,402]	[66,346]	0	hSpCas9	negative selection	4710864
44287579	44287601	21	-	27760321	HT1080	viability	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.5754252236024883	[746,582]	[357,434]	3	hSpCas9	negative selection	4710865
44289676	44289698	21	-	27760321	HT1080	viability	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.8059669782027806	[597,466]	[357,384]	4	hSpCas9	negative selection	4710866
44289762	44289784	21	+	27760321	HT1080	viability	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	1.0270019157747703	[569,444]	[453,365]	5	hSpCas9	negative selection	4710867
44286121	44286143	21	+	27760321	HT29	viability after 7 days	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.8209678789012933	[268,209]	[798,338,529]	9	hSpCas9	negative selection	4794326
44287026	44287048	21	-	27760321	HT29	viability after 7 days	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.2284451676490749	[515,402]	[744,802,539]	3	hSpCas9	negative selection	4794327
44287579	44287601	21	-	27760321	HT29	viability after 7 days	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.5932052780063609	[746,582]	[1479,1131,1282]	8	hSpCas9	negative selection	4794328
44289676	44289698	21	-	27760321	HT29	viability after 7 days	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.36677379551239364	[597,466]	[856,1138,654]	5	hSpCas9	negative selection	4794329
44289762	44289784	21	+	27760321	HT29	viability after 7 days	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.6746594635022898	[569,444]	[1052,1386,695]	8	hSpCas9	negative selection	4794330
44286121	44286143	21	+	27760321	HT29	viability after 25 days	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.7465610206733736	[268,209]	[312,451,639]	8	hSpCas9	negative selection	4877789
44287026	44287048	21	-	27760321	HT29	viability after 25 days	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.043919344121068016	[515,402]	[341,673,628]	0	hSpCas9	negative selection	4877790
44287579	44287601	21	-	27760321	HT29	viability after 25 days	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.5862942779974921	[746,582]	[998,1171,1272]	6	hSpCas9	negative selection	4877791
44289676	44289698	21	-	27760321	HT29	viability after 25 days	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.8497625510377679	[597,466]	[945,1299,1046]	8	hSpCas9	negative selection	4877792
44289762	44289784	21	+	27760321	HT29	viability after 25 days	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.473657130744089	[569,444]	[710,627,1113]	5	hSpCas9	negative selection	4877793
44286121	44286143	21	+	27760321	HT29	viability after 22 days	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.7666015638019739	[268,209]	[526,370,513]	8	hSpCas9	negative selection	4961252
44287026	44287048	21	-	27760321	HT29	viability after 22 days	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	-0.05015552379310434	[515,402]	[554,477,504]	0	hSpCas9	negative selection	4961253
44287579	44287601	21	-	27760321	HT29	viability after 22 days	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.4279669764146711	[746,582]	[1046,956,1098]	4	hSpCas9	negative selection	4961254
44289676	44289698	21	-	27760321	HT29	viability after 22 days	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.758807653559722	[597,466]	[973,1407,741]	8	hSpCas9	negative selection	4961255
44289762	44289784	21	+	27760321	HT29	viability after 22 days	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.4476161502739717	[569,444]	[688,641,1074]	5	hSpCas9	negative selection	4961256
44286121	44286143	21	+	27760321	HT29	viability after 19 days	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.950721082493695	[268,209]	[680,612,317]	8	hSpCas9	negative selection	5044715
44287026	44287048	21	-	27760321	HT29	viability after 19 days	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.3658086330210855	[515,402]	[984,443,635]	3	hSpCas9	negative selection	5044716
44287579	44287601	21	-	27760321	HT29	viability after 19 days	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.6566636485556304	[746,582]	[1489,977,1159]	6	hSpCas9	negative selection	5044717
44289676	44289698	21	-	27760321	HT29	viability after 19 days	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.3369511590669382	[597,466]	[872,940,513]	3	hSpCas9	negative selection	5044718
44289762	44289784	21	+	27760321	HT29	viability after 19 days	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.6645917624837556	[569,444]	[928,818,1008]	6	hSpCas9	negative selection	5044719
44286121	44286143	21	+	27760321	HT29	viability after 16 days	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.8104898136877696	[268,209]	[632,552,236]	8	hSpCas9	negative selection	5128178
44287026	44287048	21	-	27760321	HT29	viability after 16 days	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.22138892531512216	[515,402]	[777,672,361]	2	hSpCas9	negative selection	5128179
44287579	44287601	21	-	27760321	HT29	viability after 16 days	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.780869807767628	[746,582]	[1293,1440,1096]	8	hSpCas9	negative selection	5128180
44289676	44289698	21	-	27760321	HT29	viability after 16 days	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.6813619319025929	[597,466]	[1183,1136,561]	7	hSpCas9	negative selection	5128181
44289762	44289784	21	+	27760321	HT29	viability after 16 days	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.5055619880617301	[569,444]	[1104,629,715]	6	hSpCas9	negative selection	5128182
44286121	44286143	21	+	27760321	HT29	viability after 13 days	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.45679502072894934	[268,209]	[272,434,432]	6	hSpCas9	negative selection	5211641
44287026	44287048	21	-	27760321	HT29	viability after 13 days	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.2512322437275086	[515,402]	[799,570,537]	3	hSpCas9	negative selection	5211642
44287579	44287601	21	-	27760321	HT29	viability after 13 days	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.5539130913829727	[746,582]	[1348,966,1083]	7	hSpCas9	negative selection	5211643
44289676	44289698	21	-	27760321	HT29	viability after 13 days	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.48257878801510323	[597,466]	[735,1097,761]	6	hSpCas9	negative selection	5211644
44289762	44289784	21	+	27760321	HT29	viability after 13 days	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.19950958619552095	[569,444]	[874,703,461]	2	hSpCas9	negative selection	5211645
44286121	44286143	21	+	27760321	HT29	viability after 10 days	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	0.9222478841014226	[268,209]	[405,578,711]	9	hSpCas9	negative selection	5295104
44287026	44287048	21	-	27760321	HT29	viability after 10 days	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	0.44676886472460525	[515,402]	[730,887,730]	6	hSpCas9	negative selection	5295105
44287579	44287601	21	-	27760321	HT29	viability after 10 days	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.4376719685476408	[746,582]	[1078,1034,1253]	6	hSpCas9	negative selection	5295106
44289676	44289698	21	-	27760321	HT29	viability after 10 days	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	0.6072933728326225	[597,466]	[1046,1328,678]	8	hSpCas9	negative selection	5295107
44289762	44289784	21	+	27760321	HT29	viability after 10 days	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.6637715780025939	[569,444]	[966,1072,973]	8	hSpCas9	negative selection	5295108
44286121	44286143	21	+	27760321	MOLM13	viability	CCCGAGGACAAGTTTCAGGTGG	AIRE	ENSG00000160224	1.004321385409907	[358,268]	[407,304]	7	hSpCas9	negative selection	5378567
44287026	44287048	21	-	27760321	MOLM13	viability	GGTGGCGGTACCAAAGCCTTGG	AIRE	ENSG00000160224	1.0733990912093372	[623,515]	[569,761]	7	hSpCas9	negative selection	5378568
44287579	44287601	21	-	27760321	MOLM13	viability	CCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.4923863618199602	[804,746]	[823,438]	3	hSpCas9	negative selection	5378569
44289676	44289698	21	-	27760321	MOLM13	viability	GTAGAACTCCCCGCCAACCTGG	AIRE	ENSG00000160224	1.32531122800774	[725,597]	[795,1046]	8	hSpCas9	negative selection	5378570
44289762	44289784	21	+	27760321	MOLM13	viability	AGCCTCTGGTTCGAGCCAAGGG	AIRE	ENSG00000160224	0.4218964876172165	[661,569]	[547,392]	3	hSpCas9	negative selection	5378571
44285864	44285887	21	+	27661255	K562	viability	GGCTCGCAGACCGGGGAGACGGG	AIRE	ENSG00000160224	-0.25264117224840055	[139,194]	[102,118]	-6	dCas9-KRAB	negative selection	5461541
44285925	44285948	21	+	27661255	K562	viability	GGGACCCGAGGCCAAGCGAGGGG	AIRE	ENSG00000160224	0.20071781799837085	[206,307]	[251,219]	7	dCas9-KRAB	negative selection	5461542
44286042	44286065	21	+	27661255	K562	viability	GCTGCACCGCACGGAGATCGCGG	AIRE	ENSG00000160224	-0.15522071970045564	[588,523]	[419,382]	-5	dCas9-KRAB	negative selection	5461543
44287024	44287047	21	-	27260156	BXPC3	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.14734827325452327	[347]	[446,375,324,463]	3	hSpCas9	negative selection	5527530
44287579	44287602	21	-	27260156	BXPC3	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.5282622910410137	[130]	[169,174,177,279]	9	hSpCas9	negative selection	5527531
44286682	44286705	21	-	27260156	BXPC3	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.025713306651093226	[335]	[304,300,382,403]	0	hSpCas9	negative selection	5527532
44286678	44286701	21	+	27260156	BXPC3	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.42054575930792715	[246]	[234,121,150,270]	-7	hSpCas9	negative selection	5591812
44288384	44288407	21	-	27260156	BXPC3	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.021234996068192125	[95]	[125,86,95,94]	0	hSpCas9	negative selection	5591813
44287009	44287032	21	+	27260156	BXPC3	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.19487453084572604	[95]	[98,45,85,124]	-4	hSpCas9	negative selection	5591814
44287024	44287047	21	-	27260156	A673	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.13817013174976767	[347]	[424,398,308,390]	-3	hSpCas9	negative selection	5648781
44287579	44287602	21	-	27260156	A673	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.40502819579669436	[130]	[183,268,147,228]	8	hSpCas9	negative selection	5648782
44286682	44286705	21	-	27260156	A673	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.13515702574059585	[335]	[451,502,394,419]	3	hSpCas9	negative selection	5648783
44286678	44286701	21	+	27260156	A673	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.0036195113329799966	[246]	[336,259,244,355]	0	hSpCas9	negative selection	5713063
44288384	44288407	21	-	27260156	A673	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.010432779146278826	[95]	[135,95,135,90]	0	hSpCas9	negative selection	5713064
44287009	44287032	21	+	27260156	A673	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.32971324721576245	[95]	[81,106,87,87]	-7	hSpCas9	negative selection	5713065
44287024	44287047	21	-	27260156	A375	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.20515727951991788	[347]	[610,305,687,269]	3	hSpCas9	negative selection	5770032
44287579	44287602	21	-	27260156	A375	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.2977676601000052	[130]	[205,326,141,105]	4	hSpCas9	negative selection	5770033
44286682	44286705	21	-	27260156	A375	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.011578172077037985	[335]	[351,457,411,347]	0	hSpCas9	negative selection	5770034
44286678	44286701	21	+	27260156	A375	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.18626978628231017	[246]	[144,228,325,302]	-3	hSpCas9	negative selection	5834314
44288384	44288407	21	-	27260156	A375	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.5051119847318088	[95]	[65,46,15,170]	-6	hSpCas9	negative selection	5834315
44287009	44287032	21	+	27260156	A375	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.09678723646738208	[95]	[120,162,54,89]	-1	hSpCas9	negative selection	5834316
44287024	44287047	21	-	27260156	COLO741	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.18214233950655423	[347]	[445,364,369]	-4	hSpCas9	negative selection	5891283
44287579	44287602	21	-	27260156	COLO741	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.7415261437789684	[130]	[293,264,280]	9	hSpCas9	negative selection	5891284
44286682	44286705	21	-	27260156	COLO741	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.25565740108419205	[335]	[610,495,442]	5	hSpCas9	negative selection	5891285
44286678	44286701	21	+	27260156	COLO741	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.14649487869337696	[246]	[291,380,367]	3	hSpCas9	negative selection	5955565
44288384	44288407	21	-	27260156	COLO741	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.3057700860318473	[95]	[298,75,95]	6	hSpCas9	negative selection	5955566
44287009	44287032	21	+	27260156	COLO741	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.057554831448101584	[95]	[143,125,114]	1	hSpCas9	negative selection	5955567
44287024	44287047	21	-	27260156	CAL120	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.2331519557618734	[347]	[425,561,525]	3	hSpCas9	negative selection	6012534
44287579	44287602	21	-	27260156	CAL120	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.4897651691858149	[130]	[285,223,185]	7	hSpCas9	negative selection	6012535
44286682	44286705	21	-	27260156	CAL120	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.48234364024586857	[335]	[633,675,451]	7	hSpCas9	negative selection	6012536
44286678	44286701	21	+	27260156	CAL120	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.21083083575998174	[246]	[328,146,328]	-3	hSpCas9	negative selection	6076816
44288384	44288407	21	-	27260156	CAL120	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.0847406950478975	[95]	[251,57,49]	-1	hSpCas9	negative selection	6076817
44287009	44287032	21	+	27260156	CAL120	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.08640916009424116	[95]	[151,147,84]	1	hSpCas9	negative selection	6076818
44287024	44287047	21	-	27260156	CADOES1	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.02556810574243601	[347]	[286,287,299,399]	0	hSpCas9	negative selection	6133785
44287579	44287602	21	-	27260156	CADOES1	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.10057496409014965	[130]	[150,124,127,117]	1	hSpCas9	negative selection	6133786
44286682	44286705	21	-	27260156	CADOES1	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.12164958521098912	[335]	[370,243,370,374]	2	hSpCas9	negative selection	6133787
44286678	44286701	21	+	27260156	CADOES1	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.27275227141521197	[246]	[192,176,163,227]	-5	hSpCas9	negative selection	6198067
44288384	44288407	21	-	27260156	CADOES1	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.2717622730277629	[95]	[61,147,122,97]	4	hSpCas9	negative selection	6198068
44287009	44287032	21	+	27260156	CADOES1	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.053887620571530626	[95]	[146,101,44,75]	0	hSpCas9	negative selection	6198069
44287024	44287047	21	-	27260156	EWS502	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.22628135596180313	[347]	[391,389,560,384]	4	hSpCas9	negative selection	6255036
44287579	44287602	21	-	27260156	EWS502	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.46831583448125413	[130]	[209,217,129,205]	7	hSpCas9	negative selection	6255037
44286682	44286705	21	-	27260156	EWS502	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.3968441860682454	[335]	[429,451,521,474]	7	hSpCas9	negative selection	6255038
44286678	44286701	21	+	27260156	EWS502	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.0691455521894151	[246]	[219,215,243,436]	1	hSpCas9	negative selection	6319318
44288384	44288407	21	-	27260156	EWS502	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.5334794187134937	[95]	[122,158,141,167]	8	hSpCas9	negative selection	6319319
44287009	44287032	21	+	27260156	EWS502	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.430830957735298	[95]	[76,80,97,42]	-6	hSpCas9	negative selection	6319320
44287024	44287047	21	-	27260156	EW8	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.14564847491350186	[347]	[269,275,341,348]	2	hSpCas9	negative selection	6376287
44287579	44287602	21	-	27260156	EW8	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.49067712382052786	[130]	[154,113,122,208]	8	hSpCas9	negative selection	6376288
44286682	44286705	21	-	27260156	EW8	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.19099921583027651	[335]	[350,399,272,229]	3	hSpCas9	negative selection	6376289
44286678	44286701	21	+	27260156	EW8	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.14296987938038197	[246]	[297,136,129,180]	-3	hSpCas9	negative selection	6440569
44288384	44288407	21	-	27260156	EW8	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.05184609168519261	[95]	[63,91,77,86]	0	hSpCas9	negative selection	6440570
44287009	44287032	21	+	27260156	EW8	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.2895168175560219	[95]	[35,95,78,37]	-5	hSpCas9	negative selection	6440571
44287024	44287047	21	-	27260156	CORL105	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.14413797518877464	[347]	[466,417,513,412]	2	hSpCas9	negative selection	6497538
44287579	44287602	21	-	27260156	CORL105	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.41865154447384634	[130]	[196,136,325,179]	7	hSpCas9	negative selection	6497539
44286682	44286705	21	-	27260156	CORL105	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.43614739525467805	[335]	[483,352,728,594]	7	hSpCas9	negative selection	6497540
44286678	44286701	21	+	27260156	CORL105	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.3911523129236256	[246]	[203,150,330,213]	-6	hSpCas9	negative selection	6561820
44288384	44288407	21	-	27260156	CORL105	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.4896790191176179	[95]	[38,65,168,58]	-7	hSpCas9	negative selection	6561821
44287009	44287032	21	+	27260156	CORL105	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.7754504684690731	[95]	[33,62,112,58]	-8	hSpCas9	negative selection	6561822
44287024	44287047	21	-	27260156	HS294T	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.1266246999867403	[347]	[162,93,92,142]	-2	hSpCas9	negative selection	6618789
44287579	44287602	21	-	27260156	HS294T	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	-0.4873542421070771	[130]	[21,33,52,36]	-6	hSpCas9	negative selection	6618790
44286682	44286705	21	-	27260156	HS294T	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.3991060004612033	[335]	[147,105,284,145]	5	hSpCas9	negative selection	6618791
44286678	44286701	21	+	27260156	HS294T	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.7438313729469226	[246]	[55,47,63,60]	-8	hSpCas9	negative selection	6683071
44288384	44288407	21	-	27260156	HS294T	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.6128433584615443	[95]	[13,29,130,56]	7	hSpCas9	negative selection	6683072
44287009	44287032	21	+	27260156	HS294T	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.12000438533227875	[95]	[54,17,39,48]	1	hSpCas9	negative selection	6683073
44287024	44287047	21	-	27260156	HCC44	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.4791099309010142	[347]	[683,506,378,606]	7	hSpCas9	negative selection	6740040
44287579	44287602	21	-	27260156	HCC44	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	-0.03233237089484997	[130]	[153,76,221,148]	0	hSpCas9	negative selection	6740041
44286682	44286705	21	-	27260156	HCC44	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.03514079814593002	[335]	[374,214,543,397]	0	hSpCas9	negative selection	6740042
44286678	44286701	21	+	27260156	HCC44	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.31901812348001823	[246]	[445,298,171,455]	5	hSpCas9	negative selection	6804322
44288384	44288407	21	-	27260156	HCC44	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.3848041959698949	[95]	[90,154,199,123]	6	hSpCas9	negative selection	6804323
44287009	44287032	21	+	27260156	HCC44	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.3511973958557335	[95]	[91,70,311,113]	6	hSpCas9	negative selection	6804324
44287024	44287047	21	-	27260156	G402	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.4222289380222518	[347]	[473,753,540,504]	5	hSpCas9	negative selection	6861291
44287579	44287602	21	-	27260156	G402	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.2909674006660308	[130]	[134,92,283,251]	3	hSpCas9	negative selection	6861292
44286682	44286705	21	-	27260156	G402	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.19954741157570077	[335]	[385,247,598,615]	2	hSpCas9	negative selection	6861293
44286678	44286701	21	+	27260156	G402	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.2082314443866542	[246]	[436,184,359,89]	-3	hSpCas9	negative selection	6925573
44288384	44288407	21	-	27260156	G402	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.14192326555003998	[95]	[50,314,20,128]	1	hSpCas9	negative selection	6925574
44287009	44287032	21	+	27260156	G402	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.7060891112243426	[95]	[152,25,23,91]	-7	hSpCas9	negative selection	6925575
44287024	44287047	21	-	27260156	L33	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.3495184469305168	[347]	[321,84,164,298]	-7	hSpCas9	negative selection	6982542
44287579	44287602	21	-	27260156	L33	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.34919309922638786	[130]	[165,57,128,154]	7	hSpCas9	negative selection	6982543
44286682	44286705	21	-	27260156	L33	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.5631260814931033	[335]	[464,223,326,454]	9	hSpCas9	negative selection	6982544
44286678	44286701	21	+	27260156	L33	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.04647427208445043	[246]	[218,112,162,266]	1	hSpCas9	negative selection	7046824
44288384	44288407	21	-	27260156	L33	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.06547875691581595	[95]	[115,24,76,101]	1	hSpCas9	negative selection	7046825
44287009	44287032	21	+	27260156	L33	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.08878836413146596	[95]	[132,44,53,78]	2	hSpCas9	negative selection	7046826
44287024	44287047	21	-	27260156	K562	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.3686070916383585	[347]	[101,281,221,329]	-4	hSpCas9	negative selection	7103793
44287579	44287602	21	-	27260156	K562	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.05336879201979228	[130]	[272,15,201,10]	0	hSpCas9	negative selection	7103794
44286682	44286705	21	-	27260156	K562	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.33883429067096865	[335]	[183,333,132,285]	-4	hSpCas9	negative selection	7103795
44286678	44286701	21	+	27260156	K562	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.0782593421779757	[246]	[270,427,99,148]	0	hSpCas9	negative selection	7168075
44288384	44288407	21	-	27260156	K562	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.9999042761913421	[95]	[5,39,105,17]	-8	hSpCas9	negative selection	7168076
44287009	44287032	21	+	27260156	K562	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-1.422797457546912	[95]	[31,28,44,21]	-9	hSpCas9	negative selection	7168077
44287024	44287047	21	-	27260156	HT29	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.22109794788357315	[347]	[483,433,497,540]	4	hSpCas9	negative selection	7225044
44287579	44287602	21	-	27260156	HT29	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.9279759349072154	[130]	[400,347,239,239]	9	hSpCas9	negative selection	7225045
44286682	44286705	21	-	27260156	HT29	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.12279100654476488	[335]	[424,445,491,414]	2	hSpCas9	negative selection	7225046
44286678	44286701	21	+	27260156	HT29	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.31276614516783074	[246]	[268,260,170,264]	-6	hSpCas9	negative selection	7289326
44288384	44288407	21	-	27260156	HT29	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.3381712287172096	[95]	[132,272,83,112]	6	hSpCas9	negative selection	7289327
44287009	44287032	21	+	27260156	HT29	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.6193689816543047	[95]	[214,100,280,121]	9	hSpCas9	negative selection	7289328
44287024	44287047	21	-	27260156	MHHES1	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.05357835648491538	[347]	[583,371,388,218]	-1	hSpCas9	negative selection	7346295
44287579	44287602	21	-	27260156	MHHES1	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.20036895084674589	[130]	[136,245,136,159]	3	hSpCas9	negative selection	7346296
44286682	44286705	21	-	27260156	MHHES1	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.3229750081198065	[335]	[460,515,550,379]	6	hSpCas9	negative selection	7346297
44286678	44286701	21	+	27260156	MHHES1	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.1392881413291629	[246]	[187,244,268,285]	-3	hSpCas9	negative selection	7410577
44288384	44288407	21	-	27260156	MHHES1	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.5668819989482472	[95]	[74,133,27,61]	-8	hSpCas9	negative selection	7410578
44287009	44287032	21	+	27260156	MHHES1	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-1.263824811409071	[95]	[64,17,56,39]	-9	hSpCas9	negative selection	7410579
44287024	44287047	21	-	27260156	MEWO	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.23799583147568937	[347]	[418,238,197]	-5	hSpCas9	negative selection	7467546
44287579	44287602	21	-	27260156	MEWO	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.7333314091053678	[130]	[192,228,186]	9	hSpCas9	negative selection	7467547
44286682	44286705	21	-	27260156	MEWO	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.17146901236004536	[335]	[367,290,405]	4	hSpCas9	negative selection	7467548
44286678	44286701	21	+	27260156	MEWO	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.38510247821439814	[246]	[227,299,362]	7	hSpCas9	negative selection	7531828
44288384	44288407	21	-	27260156	MEWO	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.15799069275609545	[95]	[62,97,76]	-3	hSpCas9	negative selection	7531829
44287009	44287032	21	+	27260156	MEWO	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.13486512731671008	[95]	[195,34,83]	3	hSpCas9	negative selection	7531830
44287024	44287047	21	-	27260156	LNCAPCLONEFGC	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.13078547612437547	[347]	[216,344,527,319]	2	hSpCas9	negative selection	7588797
44287579	44287602	21	-	27260156	LNCAPCLONEFGC	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.1737241182501208	[130]	[171,66,207,102]	2	hSpCas9	negative selection	7588798
44286682	44286705	21	-	27260156	LNCAPCLONEFGC	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.33818285490540195	[335]	[403,275,521,363]	5	hSpCas9	negative selection	7588799
44286678	44286701	21	+	27260156	LNCAPCLONEFGC	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.04795198342841833	[246]	[175,152,306,247]	0	hSpCas9	negative selection	7653079
44288384	44288407	21	-	27260156	LNCAPCLONEFGC	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.4864792772562039	[95]	[74,34,103,41]	-6	hSpCas9	negative selection	7653080
44287009	44287032	21	+	27260156	LNCAPCLONEFGC	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.37967336336881097	[95]	[27,50,92,100]	-5	hSpCas9	negative selection	7653081
44287024	44287047	21	-	27260156	PANC0327	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.17738874238559932	[347]	[306,203,247,345]	-3	hSpCas9	negative selection	7710048
44287579	44287602	21	-	27260156	PANC0327	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.14091783554164206	[130]	[67,143,43,249]	2	hSpCas9	negative selection	7710049
44286682	44286705	21	-	27260156	PANC0327	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.24386552653482613	[335]	[416,404,234,354]	3	hSpCas9	negative selection	7710050
44286678	44286701	21	+	27260156	PANC0327	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.22816068916274745	[246]	[164,195,79,304]	-3	hSpCas9	negative selection	7774330
44288384	44288407	21	-	27260156	PANC0327	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.26186541771793337	[95]	[144,151,52,55]	4	hSpCas9	negative selection	7774331
44287009	44287032	21	+	27260156	PANC0327	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.5962692950940811	[95]	[41,35,37,110]	-7	hSpCas9	negative selection	7774332
44287024	44287047	21	-	27260156	NCIH2009	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.21623049113802306	[347]	[362,358,522]	-3	hSpCas9	negative selection	7831299
44287579	44287602	21	-	27260156	NCIH2009	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.7419484394015645	[130]	[260,353,292]	8	hSpCas9	negative selection	7831300
44286682	44286705	21	-	27260156	NCIH2009	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.4804994756342152	[335]	[891,361,761]	6	hSpCas9	negative selection	7831301
44286678	44286701	21	+	27260156	NCIH2009	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.0649906573392528	[246]	[347,460,268]	0	hSpCas9	negative selection	7895581
44288384	44288407	21	-	27260156	NCIH2009	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.6979213366010564	[95]	[76,70,98]	-7	hSpCas9	negative selection	7895582
44287009	44287032	21	+	27260156	NCIH2009	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.17069344498790873	[95]	[164,174,114]	2	hSpCas9	negative selection	7895583
44287024	44287047	21	-	27260156	NCIH1373	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.16875092781584639	[347]	[262,534,189,196]	1	hSpCas9	negative selection	7952550
44287579	44287602	21	-	27260156	NCIH1373	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.00478628023976202	[130]	[115,207,108,37]	0	hSpCas9	negative selection	7952551
44286682	44286705	21	-	27260156	NCIH1373	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.13970302100909376	[335]	[277,469,301,75]	-1	hSpCas9	negative selection	7952552
44286678	44286701	21	+	27260156	NCIH1373	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.44854911241355366	[246]	[344,194,128,42]	-4	hSpCas9	negative selection	8016832
44288384	44288407	21	-	27260156	NCIH1373	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.23577038214923363	[95]	[71,100,141,10]	-2	hSpCas9	negative selection	8016833
44287009	44287032	21	+	27260156	NCIH1373	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.5240026787319674	[95]	[46,69,13,44]	-5	hSpCas9	negative selection	8016834
44287024	44287047	21	-	27260156	PATU8902	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.22004133228596098	[347]	[685,635,464,480]	2	hSpCas9	negative selection	8073801
44287579	44287602	21	-	27260156	PATU8902	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.9612160831317192	[130]	[314,340,265,541]	9	hSpCas9	negative selection	8073802
44286682	44286705	21	-	27260156	PATU8902	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.3387612462922227	[335]	[1094,396,402,497]	3	hSpCas9	negative selection	8073803
44286678	44286701	21	+	27260156	PATU8902	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.4099777935700899	[246]	[137,545,215,131]	-4	hSpCas9	negative selection	8138083
44288384	44288407	21	-	27260156	PATU8902	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.23271472688099948	[95]	[354,137,30,129]	2	hSpCas9	negative selection	8138084
44287009	44287032	21	+	27260156	PATU8902	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.3189348417263467	[95]	[32,139,90,457]	3	hSpCas9	negative selection	8138085
44287024	44287047	21	-	27260156	PANC1	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.3401359047713418	[347]	[418,510,235,367]	5	hSpCas9	negative selection	8195052
44287579	44287602	21	-	27260156	PANC1	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	-0.18224934829193784	[130]	[63,156,96,90]	-3	hSpCas9	negative selection	8195053
44286682	44286705	21	-	27260156	PANC1	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.10965469479975692	[335]	[258,406,236,201]	-2	hSpCas9	negative selection	8195054
44286678	44286701	21	+	27260156	PANC1	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.05195302322170714	[246]	[120,296,207,260]	0	hSpCas9	negative selection	8259334
44288384	44288407	21	-	27260156	PANC1	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.2006697822271275	[95]	[61,78,77,68]	-3	hSpCas9	negative selection	8259335
44287009	44287032	21	+	27260156	PANC1	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-1.053351075650487	[95]	[39,57,24,38]	-8	hSpCas9	negative selection	8259336
44287024	44287047	21	-	27260156	PANC0813	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.09197722085304127	[347]	[622,212,481,245]	-1	hSpCas9	negative selection	8316303
44287579	44287602	21	-	27260156	PANC0813	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.44998797705776594	[130]	[251,242,190,160]	7	hSpCas9	negative selection	8316304
44286682	44286705	21	-	27260156	PANC0813	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.5060572085309504	[335]	[489,689,644,417]	7	hSpCas9	negative selection	8316305
44286678	44286701	21	+	27260156	PANC0813	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.3823831250625165	[246]	[294,260,183,159]	-5	hSpCas9	negative selection	8380585
44288384	44288407	21	-	27260156	PANC0813	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.29928229733744605	[95]	[155,49,197,151]	5	hSpCas9	negative selection	8380586
44287009	44287032	21	+	27260156	PANC0813	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.041434817647551636	[95]	[63,117,72,174]	0	hSpCas9	negative selection	8380587
44287024	44287047	21	-	27260156	RDES	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.16886174279225585	[347]	[245,399,354,445]	-3	hSpCas9	negative selection	8437554
44287579	44287602	21	-	27260156	RDES	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.1417702129527738	[130]	[131,163,154,224]	2	hSpCas9	negative selection	8437555
44286682	44286705	21	-	27260156	RDES	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.010842029086166827	[335]	[339,342,462,421]	0	hSpCas9	negative selection	8437556
44286678	44286701	21	+	27260156	RDES	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.11766752495434685	[246]	[199,221,203,458]	-2	hSpCas9	negative selection	8501836
44288384	44288407	21	-	27260156	RDES	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.268656721814041	[95]	[57,114,181,204]	4	hSpCas9	negative selection	8501837
44287009	44287032	21	+	27260156	RDES	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.7759892852411014	[95]	[66,39,67,85]	-8	hSpCas9	negative selection	8501838
44287024	44287047	21	-	27260156	PC3	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.043550002512891595	[347]	[202,324,602,435]	1	hSpCas9	negative selection	8558805
44287579	44287602	21	-	27260156	PC3	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	-0.431133421091612	[130]	[46,123,169,86]	-7	hSpCas9	negative selection	8558806
44286682	44286705	21	-	27260156	PC3	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.24862674492339296	[335]	[186,457,735,400]	5	hSpCas9	negative selection	8558807
44286678	44286701	21	+	27260156	PC3	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.026566040340719743	[246]	[111,277,281,389]	0	hSpCas9	negative selection	8623087
44288384	44288407	21	-	27260156	PC3	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.351309249118962	[95]	[71,59,276,155]	7	hSpCas9	negative selection	8623088
44287009	44287032	21	+	27260156	PC3	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.6763394873349098	[95]	[39,63,52,82]	-9	hSpCas9	negative selection	8623089
44287024	44287047	21	-	27260156	PATU8988T	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.16856438136074048	[347]	[331,242,318,296]	-3	hSpCas9	negative selection	8680056
44287579	44287602	21	-	27260156	PATU8988T	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.31459869441505584	[130]	[110,202,131,190]	5	hSpCas9	negative selection	8680057
44286682	44286705	21	-	27260156	PATU8988T	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	-0.2246858098471915	[335]	[242,335,416,104]	-4	hSpCas9	negative selection	8680058
44286678	44286701	21	+	27260156	PATU8988T	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.16007452834901326	[246]	[263,345,124,125]	-3	hSpCas9	negative selection	8744338
44288384	44288407	21	-	27260156	PATU8988T	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.9621719095728123	[95]	[42,72,39,35]	-8	hSpCas9	negative selection	8744339
44287009	44287032	21	+	27260156	PATU8988T	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.35728672311273346	[95]	[85,54,93,50]	-5	hSpCas9	negative selection	8744340
44287024	44287047	21	-	27260156	T47D	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.22733524833275465	[347]	[320,282,419,365]	-5	hSpCas9	negative selection	8801307
44287579	44287602	21	-	27260156	T47D	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.04512104898434144	[130]	[187,106,159,179]	0	hSpCas9	negative selection	8801308
44286682	44286705	21	-	27260156	T47D	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.07858958885195899	[335]	[418,349,410,480]	1	hSpCas9	negative selection	8801309
44286678	44286701	21	+	27260156	T47D	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.055409941422775	[246]	[263,231,305,309]	-1	hSpCas9	negative selection	8865589
44288384	44288407	21	-	27260156	T47D	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.2278007965759432	[95]	[83,98,92,105]	-5	hSpCas9	negative selection	8865590
44287009	44287032	21	+	27260156	T47D	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.5305418412181111	[95]	[61,67,82,97]	-8	hSpCas9	negative selection	8865591
44287024	44287047	21	-	27260156	SU8686	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.2721924550487763	[347]	[283,323,175,360]	-4	hSpCas9	negative selection	8922558
44287579	44287602	21	-	27260156	SU8686	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.5534110110269099	[130]	[215,211,151,170]	8	hSpCas9	negative selection	8922559
44286682	44286705	21	-	27260156	SU8686	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.5388405885221319	[335]	[506,433,454,549]	8	hSpCas9	negative selection	8922560
44286678	44286701	21	+	27260156	SU8686	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	0.04308927221331749	[246]	[280,168,249,326]	0	hSpCas9	negative selection	8986840
44288384	44288407	21	-	27260156	SU8686	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.44838044614156125	[95]	[45,76,98,56]	-6	hSpCas9	negative selection	8986841
44287009	44287032	21	+	27260156	SU8686	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.2666456819373475	[95]	[90,63,141,180]	4	hSpCas9	negative selection	8986842
44287024	44287047	21	-	27260156	SKES1	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	-0.08355219156714655	[347]	[352,434,323,223]	-2	hSpCas9	negative selection	9043809
44287579	44287602	21	-	27260156	SKES1	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.1851893966620186	[130]	[180,173,76,166]	4	hSpCas9	negative selection	9043810
44286682	44286705	21	-	27260156	SKES1	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.32523200936631347	[335]	[538,436,367,357]	6	hSpCas9	negative selection	9043811
44286678	44286701	21	+	27260156	SKES1	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.4126939482951295	[246]	[228,147,155,204]	-7	hSpCas9	negative selection	9108091
44288384	44288407	21	-	27260156	SKES1	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.04429192255475156	[95]	[179,80,79,45]	-1	hSpCas9	negative selection	9108092
44287009	44287032	21	+	27260156	SKES1	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.050068889656963655	[95]	[101,105,110,56]	-1	hSpCas9	negative selection	9108093
44287024	44287047	21	-	27260156	TOV112D	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.30739820642451443	[347]	[351,503,421,456]	6	hSpCas9	negative selection	9165060
44287579	44287602	21	-	27260156	TOV112D	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.12475184272747009	[130]	[223,119,117,111]	2	hSpCas9	negative selection	9165061
44286682	44286705	21	-	27260156	TOV112D	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.5616350344766712	[335]	[414,462,568,522]	8	hSpCas9	negative selection	9165062
44286678	44286701	21	+	27260156	TOV112D	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.1724255583220664	[246]	[256,206,274,140]	-3	hSpCas9	negative selection	9229342
44288384	44288407	21	-	27260156	TOV112D	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	-0.7972136261970646	[95]	[69,81,56,20]	-9	hSpCas9	negative selection	9229343
44287009	44287032	21	+	27260156	TOV112D	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.041291065013307815	[95]	[83,144,117,39]	-1	hSpCas9	negative selection	9229344
44287024	44287047	21	-	27260156	TC71	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.2964223106567352	[347]	[438,332,421,651]	7	hSpCas9	negative selection	9286311
44287579	44287602	21	-	27260156	TC71	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.2690571805599	[130]	[209,173,167,120]	6	hSpCas9	negative selection	9286312
44286682	44286705	21	-	27260156	TC71	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.15710378254957807	[335]	[442,465,286,413]	4	hSpCas9	negative selection	9286313
44286678	44286701	21	+	27260156	TC71	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.22278883496946378	[246]	[193,257,220,235]	-5	hSpCas9	negative selection	9350593
44288384	44288407	21	-	27260156	TC71	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.2289819926937433	[95]	[145,103,112,118]	5	hSpCas9	negative selection	9350594
44287009	44287032	21	+	27260156	TC71	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	0.10621569753364746	[95]	[93,106,88,156]	2	hSpCas9	negative selection	9350595
44287024	44287047	21	-	27260156	TC32	viability	GTGGCGGTACCAAAGCCTTGGGG	AIRE	ENSG00000160224	0.08775344029543014	[347]	[364,174,451,466]	1	hSpCas9	negative selection	9407562
44287579	44287602	21	-	27260156	TC32	viability	CCCCGCTCACCGTTCCCGAGTGG	AIRE	ENSG00000160224	0.16905703564988595	[130]	[87,97,177,214]	3	hSpCas9	negative selection	9407563
44286682	44286705	21	-	27260156	TC32	viability	GCAGCCGGCCATAGCGCTCCAGG	AIRE	ENSG00000160224	0.37623724829742	[335]	[433,377,444,367]	6	hSpCas9	negative selection	9407564
44286678	44286701	21	+	27260156	TC32	viability	ACAACCTGGAGCGCTATGGCCGG	AIRE	ENSG00000160224	-0.08034125136477233	[246]	[202,171,385,148]	-1	hSpCas9	negative selection	9471844
44288384	44288407	21	-	27260156	TC32	viability	CGGGACGTCCCCGGAGGACATGG	AIRE	ENSG00000160224	0.16060736444302348	[95]	[96,55,85,177]	3	hSpCas9	negative selection	9471845
44287009	44287032	21	+	27260156	TC32	viability	GAAGCCCCCGGCCGTCCCCAAGG	AIRE	ENSG00000160224	-0.9146822483105161	[95]	[58,5,102,44]	-9	hSpCas9	negative selection	9471846
44286030	44286053	21	-	27869803	HPAFII	viability after 27 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.013109770945984422	[768]	[380,416,NaN]	0	hSpCas9	negative selection	9579514
44286664	44286687	21	+	27869803	HPAFII	viability after 27 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.20850588356195288	[406]	[308,81,NaN]	-1	hSpCas9	negative selection	9579515
44286978	44287001	21	+	27869803	HPAFII	viability after 27 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-0.44863779601261217	[239]	[140,51,NaN]	-3	hSpCas9	negative selection	9579516
44287570	44287593	21	+	27869803	HPAFII	viability after 27 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.07403964129245832	[485]	[161,309,NaN]	0	hSpCas9	negative selection	9579517
44288354	44288377	21	-	27869803	HPAFII	viability after 27 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.07590572140254381	[112]	[69,44,NaN]	0	hSpCas9	negative selection	9579518
44289653	44289676	21	-	27869803	HPAFII	viability after 27 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	1.5358934423742403	[25]	[85,0,NaN]	9	hSpCas9	negative selection	9579519
44286030	44286053	21	-	27869803	HPAFII	viability after 15 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	0.09462106649482993	[768]	[945,842,NaN]	1	hSpCas9	negative selection	9661963
44286664	44286687	21	+	27869803	HPAFII	viability after 15 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.07457181516806899	[406]	[727,220,NaN]	-1	hSpCas9	negative selection	9661964
44286978	44287001	21	+	27869803	HPAFII	viability after 15 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	-0.19851179620063988	[239]	[336,154,NaN]	-2	hSpCas9	negative selection	9661965
44287570	44287593	21	+	27869803	HPAFII	viability after 15 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.27628398195276804	[485]	[618,640,NaN]	3	hSpCas9	negative selection	9661966
44288354	44288377	21	-	27869803	HPAFII	viability after 15 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.5636202089812581	[112]	[112,62,NaN]	-6	hSpCas9	negative selection	9661967
44289653	44289676	21	-	27869803	HPAFII	viability after 15 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	0.5942617169438651	[25]	[64,27,NaN]	6	hSpCas9	negative selection	9661968
44286030	44286053	21	-	27869803	ASPC1	viability after 36 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	1.2193457270012864	[1401]	[1748,1107,724]	9	hSpCas9	negative selection	9744412
44286664	44286687	21	+	27869803	ASPC1	viability after 36 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.09213827431687749	[802]	[223,468,212]	0	hSpCas9	negative selection	9744413
44286978	44287001	21	+	27869803	ASPC1	viability after 36 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.1833112826551358	[405]	[139,151,180]	1	hSpCas9	negative selection	9744414
44287570	44287593	21	+	27869803	ASPC1	viability after 36 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.5530897349216866	[1181]	[699,808,370]	5	hSpCas9	negative selection	9744415
44288354	44288377	21	-	27869803	ASPC1	viability after 36 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	0.9334085355005048	[283]	[125,183,235]	8	hSpCas9	negative selection	9744416
44289653	44289676	21	-	27869803	ASPC1	viability after 36 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-1.129973128753942	[209]	[67,11,25]	-8	hSpCas9	negative selection	9744417
44286030	44286053	21	-	27869803	PATU8988S	viability after 35 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.29527397559699786	[1150]	[275,479,NaN]	-3	hSpCas9	negative selection	9826861
44286664	44286687	21	+	27869803	PATU8988S	viability after 35 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	-0.1118273619563405	[623]	[263,200,NaN]	-1	hSpCas9	negative selection	9826862
44286978	44287001	21	+	27869803	PATU8988S	viability after 35 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.10644081298622537	[361]	[138,174,NaN]	1	hSpCas9	negative selection	9826863
44287570	44287593	21	+	27869803	PATU8988S	viability after 35 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	-0.33167399808124826	[933]	[258,338,NaN]	-3	hSpCas9	negative selection	9826864
44288354	44288377	21	-	27869803	PATU8988S	viability after 35 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	0.10445387712943677	[239]	[67,139,NaN]	1	hSpCas9	negative selection	9826865
44289653	44289676	21	-	27869803	PATU8988S	viability after 35 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	0.007559355227368503	[162]	[62,68,NaN]	0	hSpCas9	negative selection	9826866
44286030	44286053	21	-	27869803	PATU8988S	viability after 31 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.13892125131071065	[1150]	[323,534,NaN]	-1	hSpCas9	negative selection	9909310
44286664	44286687	21	+	27869803	PATU8988S	viability after 31 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.10063323373283797	[623]	[224,319,NaN]	1	hSpCas9	negative selection	9909311
44286978	44287001	21	+	27869803	PATU8988S	viability after 31 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.5499204322452094	[361]	[220,198,NaN]	6	hSpCas9	negative selection	9909312
44287570	44287593	21	+	27869803	PATU8988S	viability after 31 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.15148171743616023	[933]	[304,551,NaN]	2	hSpCas9	negative selection	9909313
44288354	44288377	21	-	27869803	PATU8988S	viability after 31 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	0.3576959263603682	[239]	[53,209,NaN]	4	hSpCas9	negative selection	9909314
44289653	44289676	21	-	27869803	PATU8988S	viability after 31 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-0.06442846769132404	[162]	[44,83,NaN]	0	hSpCas9	negative selection	9909315
44286030	44286053	21	-	27869803	HPAFII	viability after 35 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.1531817341008248	[768]	[287,419,NaN]	-1	hSpCas9	negative selection	9991759
44286664	44286687	21	+	27869803	HPAFII	viability after 35 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.010322233725619245	[406]	[310,90,NaN]	0	hSpCas9	negative selection	9991760
44286978	44287001	21	+	27869803	HPAFII	viability after 35 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.15871407361829007	[239]	[216,43,NaN]	1	hSpCas9	negative selection	9991761
44287570	44287593	21	+	27869803	HPAFII	viability after 35 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.6212372063466378	[485]	[218,557,NaN]	4	hSpCas9	negative selection	9991762
44288354	44288377	21	-	27869803	HPAFII	viability after 35 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-0.7551630281652859	[112]	[55,8,NaN]	-4	hSpCas9	negative selection	9991763
44289653	44289676	21	-	27869803	HPAFII	viability after 35 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	-0.05703777829314616	[25]	[22,0,NaN]	0	hSpCas9	negative selection	9991764
44286030	44286053	21	-	27869803	HPAFII	viability after 31 days	TGCGGTGCAGCCTCAGAAGCCGG	AIRE	ENSG00000160224	-0.4817054470002109	[768]	[276,343,NaN]	-3	hSpCas9	negative selection	10074208
44286664	44286687	21	+	27869803	HPAFII	viability after 31 days	GCTGTTCAAGGACTACAACCTGG	AIRE	ENSG00000160224	0.3793256951120415	[406]	[466,111,NaN]	2	hSpCas9	negative selection	10074209
44286978	44287001	21	+	27869803	HPAFII	viability after 31 days	ATGTGGACCTCAGCCAGCCCCGG	AIRE	ENSG00000160224	0.05311133645956242	[239]	[200,72,NaN]	0	hSpCas9	negative selection	10074210
44287570	44287593	21	+	27869803	HPAFII	viability after 31 days	CAGCGCCTTCCACTCGGGAACGG	AIRE	ENSG00000160224	0.4261718486484709	[485]	[220,524,NaN]	3	hSpCas9	negative selection	10074211
44288354	44288377	21	-	27869803	HPAFII	viability after 31 days	TCTCTGGACTGAAGCTGACATGG	AIRE	ENSG00000160224	-1.043288245140689	[112]	[47,11,NaN]	-6	hSpCas9	negative selection	10074212
44289653	44289676	21	-	27869803	HPAFII	viability after 31 days	ATGCACTTCTTGGAGCCGCCTGG	AIRE	ENSG00000160224	1.567083100299397	[25]	[81,0,NaN]	9	hSpCas9	negative selection	10074213
44286045	44286068	21	+	28162770	P31FUJ	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-0.14474602774918266	[142]	[151]	-1	hSpCas9	negative selection	10108679
44293823	44293846	21	+	28162770	P31FUJ	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	0.2478236364920421	[85]	[119]	2	hSpCas9	negative selection	10108680
44286987	44287010	21	+	28162770	P31FUJ	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	0.10679453856599025	[210]	[266]	1	hSpCas9	negative selection	10108681
44286562	44286585	21	+	28162770	P31FUJ	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	0.32791275006010023	[39]	[58]	3	hSpCas9	negative selection	10108682
44286601	44286624	21	-	28162770	P31FUJ	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.8462693665768201	[141]	[299]	8	hSpCas9	negative selection	10108683
44289734	44289757	21	+	28162770	P31FUJ	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.8620569819270625	[514]	[1099]	8	hSpCas9	negative selection	10108684
44290028	44290051	21	-	28162770	P31FUJ	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-4.756364160471391	[22]	[0]	-9	hSpCas9	negative selection	10108685
44291186	44291209	21	-	28162770	P31FUJ	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-0.21110713331505965	[263]	[267]	-2	hSpCas9	negative selection	10108686
44293110	44293133	21	-	28162770	P31FUJ	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-2.5255839536422244	[391]	[79]	-8	hSpCas9	negative selection	10108687
44293143	44293166	21	-	28162770	P31FUJ	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.06090397973007455	[892]	[1005]	0	hSpCas9	negative selection	10108688
44286045	44286068	21	+	28162770	TF1	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10278045
44293823	44293846	21	+	28162770	TF1	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10278046
44286987	44287010	21	+	28162770	TF1	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10278047
44286562	44286585	21	+	28162770	TF1	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10278048
44286601	44286624	21	-	28162770	TF1	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	NaN	[NaN]	[71]	1	hSpCas9	negative selection	10278049
44289734	44289757	21	+	28162770	TF1	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	NaN	[NaN]	[725]	1	hSpCas9	negative selection	10278050
44290028	44290051	21	-	28162770	TF1	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	NaN	[NaN]	[10]	1	hSpCas9	negative selection	10278051
44291186	44291209	21	-	28162770	TF1	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10278052
44293110	44293133	21	-	28162770	TF1	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	NaN	[NaN]	[84]	1	hSpCas9	negative selection	10278053
44293143	44293166	21	-	28162770	TF1	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	NaN	[NaN]	[741]	1	hSpCas9	negative selection	10278054
44286045	44286068	21	+	28162770	SKM1	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.6780719051126377	[34]	[98]	6	hSpCas9	negative selection	10447411
44293823	44293846	21	+	28162770	SKM1	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	1.0584166862253221	[21]	[80]	8	hSpCas9	negative selection	10447412
44286987	44287010	21	+	28162770	SKM1	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	1.6161194143698796	[30]	[167]	9	hSpCas9	negative selection	10447413
44286562	44286585	21	+	28162770	SKM1	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-0.05646695165902882	[9]	[16]	0	hSpCas9	negative selection	10447414
44286601	44286624	21	-	28162770	SKM1	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.2876227931524928	[56]	[122]	3	hSpCas9	negative selection	10447415
44289734	44289757	21	+	28162770	SKM1	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.0032239008742862563	[148]	[263]	0	hSpCas9	negative selection	10447416
44290028	44290051	21	-	28162770	SKM1	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-0.9919266994643179	[8]	[7]	-6	hSpCas9	negative selection	10447417
44291186	44291209	21	-	28162770	SKM1	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-0.5589672921882117	[49]	[59]	-4	hSpCas9	negative selection	10447418
44293110	44293133	21	-	28162770	SKM1	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-0.9875877637399804	[82]	[73]	-6	hSpCas9	negative selection	10447419
44293143	44293166	21	-	28162770	SKM1	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.3007647949112364	[215]	[309]	-3	hSpCas9	negative selection	10447420
44286045	44286068	21	+	28162770	SKM1	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.6780719051126377	[34]	[98]	6	hSpCas9	negative selection	10616777
44293823	44293846	21	+	28162770	SKM1	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	1.0584166862253221	[21]	[80]	8	hSpCas9	negative selection	10616778
44286987	44287010	21	+	28162770	SKM1	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	1.6161194143698796	[30]	[167]	9	hSpCas9	negative selection	10616779
44286562	44286585	21	+	28162770	SKM1	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-0.05646695165902882	[9]	[16]	0	hSpCas9	negative selection	10616780
44286601	44286624	21	-	28162770	SKM1	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.2876227931524928	[56]	[122]	3	hSpCas9	negative selection	10616781
44289734	44289757	21	+	28162770	SKM1	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.0032239008742862563	[148]	[263]	0	hSpCas9	negative selection	10616782
44290028	44290051	21	-	28162770	SKM1	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-0.9919266994643179	[8]	[7]	-6	hSpCas9	negative selection	10616783
44291186	44291209	21	-	28162770	SKM1	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-0.5589672921882117	[49]	[59]	-4	hSpCas9	negative selection	10616784
44293110	44293133	21	-	28162770	SKM1	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-0.9875877637399804	[82]	[73]	-6	hSpCas9	negative selection	10616785
44293143	44293166	21	-	28162770	SKM1	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.3007647949112364	[215]	[309]	-3	hSpCas9	negative selection	10616786
44286045	44286068	21	+	28162770	PL21	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-0.8519488966591342	[140]	[33]	-5	hSpCas9	negative selection	10786143
44293823	44293846	21	+	28162770	PL21	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	0.09322441057280817	[83]	[38]	0	hSpCas9	negative selection	10786144
44286987	44287010	21	+	28162770	PL21	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	0.8670133129970937	[193]	[153]	7	hSpCas9	negative selection	10786145
44286562	44286585	21	+	28162770	PL21	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	0.3618906844859324	[58]	[32]	3	hSpCas9	negative selection	10786146
44286601	44286624	21	-	28162770	PL21	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.6916752512422075	[201]	[141]	6	hSpCas9	negative selection	10786147
44289734	44289757	21	+	28162770	PL21	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.4365798103114007	[583]	[343]	4	hSpCas9	negative selection	10786148
44290028	44290051	21	-	28162770	PL21	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	0.20013961448931994	[5]	[2]	1	hSpCas9	negative selection	10786149
44291186	44291209	21	-	28162770	PL21	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	0.7002937274061147	[180]	[127]	6	hSpCas9	negative selection	10786150
44293110	44293133	21	-	28162770	PL21	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	0.16451570475859867	[327]	[159]	1	hSpCas9	negative selection	10786151
44293143	44293166	21	-	28162770	PL21	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	0.2816919874584023	[704]	[372]	2	hSpCas9	negative selection	10786152
44286045	44286068	21	+	28162770	P31FUJ	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-0.14474602774918266	[142]	[151]	-1	hSpCas9	negative selection	10955509
44293823	44293846	21	+	28162770	P31FUJ	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	0.2478236364920421	[85]	[119]	2	hSpCas9	negative selection	10955510
44286987	44287010	21	+	28162770	P31FUJ	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	0.10679453856599025	[210]	[266]	1	hSpCas9	negative selection	10955511
44286562	44286585	21	+	28162770	P31FUJ	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	0.32791275006010023	[39]	[58]	3	hSpCas9	negative selection	10955512
44286601	44286624	21	-	28162770	P31FUJ	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.8462693665768201	[141]	[299]	8	hSpCas9	negative selection	10955513
44289734	44289757	21	+	28162770	P31FUJ	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.8620569819270625	[514]	[1099]	8	hSpCas9	negative selection	10955514
44290028	44290051	21	-	28162770	P31FUJ	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-4.756364160471391	[22]	[0]	-9	hSpCas9	negative selection	10955515
44291186	44291209	21	-	28162770	P31FUJ	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-0.21110713331505965	[263]	[267]	-2	hSpCas9	negative selection	10955516
44293110	44293133	21	-	28162770	P31FUJ	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-2.5255839536422244	[391]	[79]	-8	hSpCas9	negative selection	10955517
44293143	44293166	21	-	28162770	P31FUJ	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.06090397973007455	[892]	[1005]	0	hSpCas9	negative selection	10955518
44286045	44286068	21	+	28162770	OCIAML5	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.3274828494667156	[82]	[187]	2	hSpCas9	negative selection	11124875
44293823	44293846	21	+	28162770	OCIAML5	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	0.40427318239578836	[35]	[85]	3	hSpCas9	negative selection	11124876
44286987	44287010	21	+	28162770	OCIAML5	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	0.5885060205219844	[90]	[246]	5	hSpCas9	negative selection	11124877
44286562	44286585	21	+	28162770	OCIAML5	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-2.852066570863997	[11]	[2]	-8	hSpCas9	negative selection	11124878
44286601	44286624	21	-	28162770	OCIAML5	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	-0.3018694883035174	[111]	[163]	-2	hSpCas9	negative selection	11124879
44289734	44289757	21	+	28162770	OCIAML5	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.2647470941187531	[248]	[539]	2	hSpCas9	negative selection	11124880
44290028	44290051	21	-	28162770	OCIAML5	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-1.8520665708639967	[1]	[0]	-7	hSpCas9	negative selection	11124881
44291186	44291209	21	-	28162770	OCIAML5	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-0.5831315635905188	[121]	[146]	-4	hSpCas9	negative selection	11124882
44293110	44293133	21	-	28162770	OCIAML5	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-0.43845536437644883	[252]	[336]	-3	hSpCas9	negative selection	11124883
44293143	44293166	21	-	28162770	OCIAML5	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.36089800236918235	[608]	[855]	-3	hSpCas9	negative selection	11124884
44286045	44286068	21	+	28162770	EOL1	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	1.3171678047417812	[226]	[297]	9	hSpCas9	negative selection	11294241
44293823	44293846	21	+	28162770	EOL1	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	0.37486074559690885	[100]	[68]	3	hSpCas9	negative selection	11294242
44286987	44287010	21	+	28162770	EOL1	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	0.9053115527076173	[301]	[297]	7	hSpCas9	negative selection	11294243
44286562	44286585	21	+	28162770	EOL1	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-0.36495884562445013	[65]	[26]	-3	hSpCas9	negative selection	11294244
44286601	44286624	21	-	28162770	EOL1	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.12061291047663693	[315]	[180]	1	hSpCas9	negative selection	11294245
44289734	44289757	21	+	28162770	EOL1	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.4693770852042698	[971]	[708]	4	hSpCas9	negative selection	11294246
44290028	44290051	21	-	28162770	EOL1	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-3.4677696512082257	[20]	[0]	-9	hSpCas9	negative selection	11294247
44291186	44291209	21	-	28162770	EOL1	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-1.0754522284294656	[199]	[49]	-6	hSpCas9	negative selection	11294248
44293110	44293133	21	-	28162770	EOL1	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-0.6111194328938481	[373]	[128]	-4	hSpCas9	negative selection	11294249
44293143	44293166	21	-	28162770	EOL1	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.10719781243841497	[872]	[426]	-1	hSpCas9	negative selection	11294250
44286045	44286068	21	+	28162770	MOLM13	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-0.15023998311177666	[263]	[171]	-1	hSpCas9	negative selection	11463607
44293823	44293846	21	+	28162770	MOLM13	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	-1.578404270729356	[94]	[22]	-7	hSpCas9	negative selection	11463608
44286987	44287010	21	+	28162770	MOLM13	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	1.1053193021598704	[197]	[307]	8	hSpCas9	negative selection	11463609
44286562	44286585	21	+	28162770	MOLM13	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-5.2869981206188905	[107]	[1]	-9	hSpCas9	negative selection	11463610
44286601	44286624	21	-	28162770	MOLM13	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	-0.35027229546960814	[267]	[151]	-2	hSpCas9	negative selection	11463611
44289734	44289757	21	+	28162770	MOLM13	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.9317872753137812	[732]	[1010]	7	hSpCas9	negative selection	11463612
44290028	44290051	21	-	28162770	MOLM13	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-3.702035619897734	[17]	[0]	-9	hSpCas9	negative selection	11463613
44291186	44291209	21	-	28162770	MOLM13	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-1.436250603047905	[261]	[69]	-6	hSpCas9	negative selection	11463614
44293110	44293133	21	-	28162770	MOLM13	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	0.8049243688221495	[417]	[527]	6	hSpCas9	negative selection	11463615
44293143	44293166	21	-	28162770	MOLM13	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	0.3171507801714917	[886]	[798]	2	hSpCas9	negative selection	11463616
44286045	44286068	21	+	28162770	HEL	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-0.05882142603465046	[160]	[98]	0	hSpCas9	negative selection	11632973
44293823	44293846	21	+	28162770	HEL	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	-3.1901511821643846	[113]	[7]	-9	hSpCas9	negative selection	11632974
44286987	44287010	21	+	28162770	HEL	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	1.847330965331489	[232]	[536]	9	hSpCas9	negative selection	11632975
44286562	44286585	21	+	28162770	HEL	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	0.038667508331496236	[37]	[24]	0	hSpCas9	negative selection	11632976
44286601	44286624	21	-	28162770	HEL	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.8081624412077284	[213]	[239]	7	hSpCas9	negative selection	11632977
44289734	44289757	21	+	28162770	HEL	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	-0.09878916275436245	[738]	[441]	0	hSpCas9	negative selection	11632978
44290028	44290051	21	-	28162770	HEL	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-1.283260586555866	[18]	[4]	-6	hSpCas9	negative selection	11632979
44291186	44291209	21	-	28162770	HEL	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-0.6621157495280641	[209]	[84]	-4	hSpCas9	negative selection	11632980
44293110	44293133	21	-	28162770	HEL	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-1.8033255628991112	[375]	[68]	-7	hSpCas9	negative selection	11632981
44293143	44293166	21	-	28162770	HEL	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.8897562488266639	[809]	[279]	-5	hSpCas9	negative selection	11632982
44286045	44286068	21	+	28162770	MV411	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-1.0471831981088517	[156]	[63]	-6	hSpCas9	negative selection	11802339
44293823	44293846	21	+	28162770	MV411	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	-1.4107739319690193	[100]	[31]	-7	hSpCas9	negative selection	11802340
44286987	44287010	21	+	28162770	MV411	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	1.0485334823686971	[197]	[344]	8	hSpCas9	negative selection	11802341
44286562	44286585	21	+	28162770	MV411	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-0.6456472453007129	[38]	[20]	-4	hSpCas9	negative selection	11802342
44286601	44286624	21	-	28162770	MV411	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.48281561371370363	[157]	[185]	4	hSpCas9	negative selection	11802343
44289734	44289757	21	+	28162770	MV411	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.4909096902380514	[494]	[585]	4	hSpCas9	negative selection	11802344
44290028	44290051	21	-	28162770	MV411	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	1.5011941430285587	[12]	[30]	9	hSpCas9	negative selection	11802345
44291186	44291209	21	-	28162770	MV411	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-0.11513252860193313	[125]	[97]	-1	hSpCas9	negative selection	11802346
44293110	44293133	21	-	28162770	MV411	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-1.1630272187062445	[209]	[78]	-6	hSpCas9	negative selection	11802347
44293143	44293166	21	-	28162770	MV411	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.07505954235329138	[633]	[506]	0	hSpCas9	negative selection	11802348
44286045	44286068	21	+	28162770	MONOMAC1	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	0.11816538463949522	[85]	[106]	1	hSpCas9	negative selection	11971705
44293823	44293846	21	+	28162770	MONOMAC1	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	0.4454111483223626	[40]	[63]	4	hSpCas9	negative selection	11971706
44286987	44287010	21	+	28162770	MONOMAC1	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	-0.11986898653709382	[90]	[95]	-1	hSpCas9	negative selection	11971707
44286562	44286585	21	+	28162770	MONOMAC1	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-0.4194292683960015	[20]	[17]	-4	hSpCas9	negative selection	11971708
44286601	44286624	21	-	28162770	MONOMAC1	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	-0.3946368069447145	[124]	[108]	-3	hSpCas9	negative selection	11971709
44289734	44289757	21	+	28162770	MONOMAC1	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.8204505796692876	[327]	[663]	7	hSpCas9	negative selection	11971710
44290028	44290051	21	-	28162770	MONOMAC1	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	-2.5189649419469164	[14]	[2]	-9	hSpCas9	negative selection	11971711
44291186	44291209	21	-	28162770	MONOMAC1	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	0.3219913834768261	[96]	[138]	3	hSpCas9	negative selection	11971712
44293110	44293133	21	-	28162770	MONOMAC1	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-0.3241487649628929	[165]	[151]	-3	hSpCas9	negative selection	11971713
44293143	44293166	21	-	28162770	MONOMAC1	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	0.5028614205062623	[409]	[665]	5	hSpCas9	negative selection	11971714
44286045	44286068	21	+	28162770	OCIAML2	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-1.0317455840089498	[44]	[121]	-6	hSpCas9	negative selection	12141071
44293823	44293846	21	+	28162770	OCIAML2	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	-0.923142029939668	[12]	[37]	-6	hSpCas9	negative selection	12141072
44286987	44287010	21	+	28162770	OCIAML2	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	1.2587225848141699	[18]	[251]	9	hSpCas9	negative selection	12141073
44286562	44286585	21	+	28162770	OCIAML2	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-2.0555923259633175	[11]	[15]	-8	hSpCas9	negative selection	12141074
44286601	44286624	21	-	28162770	OCIAML2	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.835757418749423	[27]	[276]	7	hSpCas9	negative selection	12141075
44289734	44289757	21	+	28162770	OCIAML2	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.3476463831927892	[93]	[662]	3	hSpCas9	negative selection	12141076
44290028	44290051	21	-	28162770	OCIAML2	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	0.33672509681544227	[0]	[6]	3	hSpCas9	negative selection	12141077
44291186	44291209	21	-	28162770	OCIAML2	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	-0.16028970463001085	[24]	[123]	-1	hSpCas9	negative selection	12141078
44293110	44293133	21	-	28162770	OCIAML2	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-1.4854268271702415	[48]	[96]	-7	hSpCas9	negative selection	12141079
44293143	44293166	21	-	28162770	OCIAML2	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.41962692180805794	[131]	[546]	-3	hSpCas9	negative selection	12141080
44286045	44286068	21	+	28162770	OCIAML3	viability	GCACCGCACGGAGATCGCGGTGG	AIRE	ENSG00000160224	-1.169509811796253	[37]	[50]	-7	hSpCas9	negative selection	12310437
44293823	44293846	21	+	28162770	OCIAML3	viability	GAGATGGTACGGACGTGCTGCGG	AIRE	ENSG00000160224	-0.786652718266559	[31]	[55]	-5	hSpCas9	negative selection	12310438
44286987	44287010	21	+	28162770	OCIAML3	viability	TCAGCCAGCCCCGGAAGGGGAGG	AIRE	ENSG00000160224	0.5450563974133886	[41]	[184]	5	hSpCas9	negative selection	12310439
44286562	44286585	21	+	28162770	OCIAML3	viability	GCTTCATCTGAAGGAAAAGGAGG	AIRE	ENSG00000160224	-1.9350445581592302	[18]	[14]	-8	hSpCas9	negative selection	12310440
44286601	44286624	21	-	28162770	OCIAML3	viability	GCAGCCAGGACAGGAGGGCGTGG	AIRE	ENSG00000160224	0.5897895356997065	[45]	[208]	5	hSpCas9	negative selection	12310441
44289734	44289757	21	+	28162770	OCIAML3	viability	AACAAGGCCCGCAGCAGCAGTGG	AIRE	ENSG00000160224	0.4759412372384011	[155]	[654]	4	hSpCas9	negative selection	12310442
44290028	44290051	21	-	28162770	OCIAML3	viability	ACTGGGGAGGGCCAGAGGGGCGG	AIRE	ENSG00000160224	1.1429579538420431	[5]	[39]	8	hSpCas9	negative selection	12310443
44291186	44291209	21	-	28162770	OCIAML3	viability	GGGGATCTCCCGGAGCGGAGGGG	AIRE	ENSG00000160224	0.5759173611181493	[35]	[161]	5	hSpCas9	negative selection	12310444
44293110	44293133	21	-	28162770	OCIAML3	viability	GAGGAGTCCAGCCCTGGCAGCGG	AIRE	ENSG00000160224	-0.8430351881640779	[81]	[137]	-6	hSpCas9	negative selection	12310445
44293143	44293166	21	-	28162770	OCIAML3	viability	TCAGGACCCACACACAGTAGGGG	AIRE	ENSG00000160224	-0.2496731323885213	[229]	[583]	-2	hSpCas9	negative selection	12310446