Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:60529
• Symbol:ALX4
• Description:ALX homeobox 4

DataSource: http://genomecrispr.dkfz.de/#!/results/ALX4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
44275477	44275500	11	-	26472758	Jiyoye	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	1.0253047461622289	[42]	[65]	6	hSpCas9	negative selection	5758
44309606	44309629	11	+	26472758	Jiyoye	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.39567974266804395	[125]	[124]	3	hSpCas9	negative selection	5759
44309638	44309661	11	-	26472758	Jiyoye	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.37860622930910237	[50]	[49]	3	hSpCas9	negative selection	5760
44275359	44275382	11	-	26472758	Jiyoye	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.06994216399966624	[276]	[198]	0	hSpCas9	negative selection	5761
44267521	44267544	11	+	26472758	Jiyoye	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	0.3783205188336881	[100]	[98]	3	hSpCas9	negative selection	5762
44310000	44310023	11	+	26472758	Jiyoye	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.7835512604156123	[103]	[134]	5	hSpCas9	negative selection	5763
44309892	44309915	11	+	26472758	Jiyoye	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	-0.29523299062396424	[274]	[168]	-2	hSpCas9	negative selection	5764
44309874	44309897	11	-	26472758	Jiyoye	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	-0.32014004262661333	[148]	[89]	-2	hSpCas9	negative selection	5765
44309815	44309838	11	+	26472758	Jiyoye	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.08345973666712947	[332]	[236]	0	hSpCas9	negative selection	5766
44309618	44309641	11	-	26472758	Jiyoye	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	0.2696718577559385	[10]	[9]	2	hSpCas9	negative selection	5767
44275477	44275500	11	-	26472758	KBM7	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	-0.34413817265145075	[300,181]	[103,72]	-3	hSpCas9	negative selection	196876
44309606	44309629	11	+	26472758	KBM7	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.10367284310337249	[655,625]	[151,478]	1	hSpCas9	negative selection	196877
44309638	44309661	11	-	26472758	KBM7	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	1.7537432489929343	[246,226]	[460,299]	9	hSpCas9	negative selection	196878
44275359	44275382	11	-	26472758	KBM7	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.305987254504279	[999,724]	[318,328]	-3	hSpCas9	negative selection	196879
44267521	44267544	11	+	26472758	KBM7	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-0.6097575774458461	[495,370]	[136,127]	-5	hSpCas9	negative selection	196880
44310000	44310023	11	+	26472758	KBM7	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.43439756082771175	[396,557]	[411,218]	5	hSpCas9	negative selection	196881
44309892	44309915	11	+	26472758	KBM7	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	-0.04888250677098849	[703,609]	[299,295]	0	hSpCas9	negative selection	196882
44309874	44309897	11	-	26472758	KBM7	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.10966453635270819	[518,486]	[149,349]	1	hSpCas9	negative selection	196883
44309815	44309838	11	+	26472758	KBM7	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.24398755834219066	[1101,985]	[278,534]	-2	hSpCas9	negative selection	196884
44309618	44309641	11	-	26472758	KBM7	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	0.1550648360992497	[155,93]	[14,107]	1	hSpCas9	negative selection	196885
44275477	44275500	11	-	26472758	Raji	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	0.21429873929011145	[51]	[13]	2	hSpCas9	negative selection	387994
44309606	44309629	11	+	26472758	Raji	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	-0.7864509074094728	[274]	[36]	-6	hSpCas9	negative selection	387995
44309638	44309661	11	-	26472758	Raji	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.7315166333754335	[108]	[41]	6	hSpCas9	negative selection	387996
44275359	44275382	11	-	26472758	Raji	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	0.17803808893738515	[517]	[135]	1	hSpCas9	negative selection	387997
44267521	44267544	11	+	26472758	Raji	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	0.10084068950682747	[220]	[54]	0	hSpCas9	negative selection	387998
44310000	44310023	11	+	26472758	Raji	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.4170680345062147	[283]	[87]	4	hSpCas9	negative selection	387999
44309892	44309915	11	+	26472758	Raji	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	1.209263149392813	[286]	[153]	9	hSpCas9	negative selection	388000
44309874	44309897	11	-	26472758	Raji	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.10738353537359946	[179]	[44]	1	hSpCas9	negative selection	388001
44309815	44309838	11	+	26472758	Raji	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.33822464590968027	[778]	[142]	-3	hSpCas9	negative selection	388002
44309618	44309641	11	-	26472758	Raji	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	-0.9679045919306377	[117]	[13]	-6	hSpCas9	negative selection	388003
44275477	44275500	11	-	26472758	K562	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	-0.20019188699574397	[229]	[168]	-1	hSpCas9	negative selection	579112
44309606	44309629	11	+	26472758	K562	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.38605013703905844	[348]	[384]	3	hSpCas9	negative selection	579113
44309638	44309661	11	-	26472758	K562	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	-1.0332853669642321	[256]	[105]	-5	hSpCas9	negative selection	579114
44275359	44275382	11	-	26472758	K562	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.859085848087413	[779]	[362]	-5	hSpCas9	negative selection	579115
44267521	44267544	11	+	26472758	K562	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-0.5403132854304868	[347]	[201]	-3	hSpCas9	negative selection	579116
44310000	44310023	11	+	26472758	K562	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.2236601674996495	[349]	[344]	1	hSpCas9	negative selection	579117
44309892	44309915	11	+	26472758	K562	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.27303940560621487	[548]	[559]	2	hSpCas9	negative selection	579118
44309874	44309897	11	-	26472758	K562	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.08893746298745661	[322]	[289]	0	hSpCas9	negative selection	579119
44309815	44309838	11	+	26472758	K562	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.2258827904745878	[815]	[588]	-1	hSpCas9	negative selection	579120
44309618	44309641	11	-	26472758	K562	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	-0.4780472968046441	[32]	[19]	-3	hSpCas9	negative selection	579121
44264931	44264954	11	-	26627737	DLD1	viability	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.7453890018622855	[354]	[132,150,260]	7	hSpCas9	negative selection	778509
44264945	44264968	11	+	26627737	DLD1	viability	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.2008797713625271	[488]	[191,243,104]	2	hSpCas9	negative selection	778510
44275572	44275595	11	-	26627737	DLD1	viability	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.7419048999732043	[742]	[147,226,57]	-6	hSpCas9	negative selection	778511
44275604	44275627	11	+	26627737	DLD1	viability	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.11771499469940716	[726]	[248,193,287]	1	hSpCas9	negative selection	778512
44309974	44309997	11	+	26627737	DLD1	viability	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.16803815474505734	[1733]	[631,602,593]	1	hSpCas9	negative selection	778513
44310004	44310027	11	+	26627737	DLD1	viability	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	-1.0043527884570984	[190]	[21,68,3]	-7	hSpCas9	negative selection	778514
44264931	44264954	11	-	26627737	GBM cells	viability after 5 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.5926346906534856	[148]	[163,76]	8	hSpCas9	negative selection	860824
44264945	44264968	11	+	26627737	GBM cells	viability after 5 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.0867290352238872	[186]	[129,82]	1	hSpCas9	negative selection	860825
44275572	44275595	11	-	26627737	GBM cells	viability after 5 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.25836691730440386	[425]	[226,154]	-4	hSpCas9	negative selection	860826
44275604	44275627	11	+	26627737	GBM cells	viability after 5 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.5035235876135247	[303]	[114,114]	-7	hSpCas9	negative selection	860827
44309974	44309997	11	+	26627737	GBM cells	viability after 5 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.2794031475798582	[728]	[510,437]	4	hSpCas9	negative selection	860828
44310004	44310027	11	+	26627737	GBM cells	viability after 5 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	-0.2874992493451958	[98]	[50,35]	-4	hSpCas9	negative selection	860829
44264931	44264954	11	-	26627737	GBM cells	viability after 13 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.7622824135194788	[148]	[108,159]	8	hSpCas9	negative selection	943139
44264945	44264968	11	+	26627737	GBM cells	viability after 13 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.1367743862889116	[186]	[110,111]	1	hSpCas9	negative selection	943140
44275572	44275595	11	-	26627737	GBM cells	viability after 13 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.500433215312636	[425]	[185,144]	-5	hSpCas9	negative selection	943141
44275604	44275627	11	+	26627737	GBM cells	viability after 13 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-1.6894524316858759	[303]	[54,47]	-9	hSpCas9	negative selection	943142
44309974	44309997	11	+	26627737	GBM cells	viability after 13 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.25175370342896697	[728]	[583,378]	3	hSpCas9	negative selection	943143
44310004	44310027	11	+	26627737	GBM cells	viability after 13 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	0.7518889228521092	[98]	[106,76]	8	hSpCas9	negative selection	943144
44264931	44264954	11	-	26627737	GBM cells	viability after 21 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.8274231655756168	[148]	[151,135]	7	hSpCas9	negative selection	1025454
44264945	44264968	11	+	26627737	GBM cells	viability after 21 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.48568002520466785	[186]	[147,136]	5	hSpCas9	negative selection	1025455
44275572	44275595	11	-	26627737	GBM cells	viability after 21 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.22584851845003018	[425]	[211,184]	-2	hSpCas9	negative selection	1025456
44275604	44275627	11	+	26627737	GBM cells	viability after 21 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-1.146375625842797	[303]	[71,76]	-7	hSpCas9	negative selection	1025457
44309974	44309997	11	+	26627737	GBM cells	viability after 21 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.04437049584641106	[728]	[370,395]	0	hSpCas9	negative selection	1025458
44310004	44310027	11	+	26627737	GBM cells	viability after 21 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	1.137182942988475	[98]	[122,113]	9	hSpCas9	negative selection	1025459
44264931	44264954	11	-	26627737	RPE1	viability after 9 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	-0.24249361975130002	[970]	[173,363]	-2	hSpCas9	negative selection	1107769
44264945	44264968	11	+	26627737	RPE1	viability after 9 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	1.173513847689075	[676]	[574,352]	7	hSpCas9	negative selection	1107770
44275572	44275595	11	-	26627737	RPE1	viability after 9 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.26351566254827785	[1521]	[399,392]	-2	hSpCas9	negative selection	1107771
44275604	44275627	11	+	26627737	RPE1	viability after 9 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.22762638232780041	[1090]	[268,320]	-2	hSpCas9	negative selection	1107772
44309974	44309997	11	+	26627737	RPE1	viability after 9 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.7312554665550524	[2296]	[554,275]	-5	hSpCas9	negative selection	1107773
44310004	44310027	11	+	26627737	RPE1	viability after 9 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	3.187143512738316	[63]	[178,186]	9	hSpCas9	negative selection	1107774
44264931	44264954	11	-	26627737	RPE1	viability after 12 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.06478592711945236	[970]	[233,313]	0	hSpCas9	negative selection	1190084
44264945	44264968	11	+	26627737	RPE1	viability after 12 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	1.3296006558152615	[676]	[665,235]	7	hSpCas9	negative selection	1190085
44275572	44275595	11	-	26627737	RPE1	viability after 12 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.23185036151264637	[1521]	[639,310]	1	hSpCas9	negative selection	1190086
44275604	44275627	11	+	26627737	RPE1	viability after 12 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.6863581224550814	[1090]	[341,608]	4	hSpCas9	negative selection	1190087
44309974	44309997	11	+	26627737	RPE1	viability after 12 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.2581964742815317	[2296]	[532,497]	-2	hSpCas9	negative selection	1190088
44310004	44310027	11	+	26627737	RPE1	viability after 12 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	3.2908803134459945	[63]	[109,229]	9	hSpCas9	negative selection	1190089
44264931	44264954	11	-	26627737	RPE1	viability after 15 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	-0.1326121593896373	[970]	[331,171]	-1	hSpCas9	negative selection	1272399
44264945	44264968	11	+	26627737	RPE1	viability after 15 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	1.2560008800634501	[676]	[716,206]	7	hSpCas9	negative selection	1272400
44275572	44275595	11	-	26627737	RPE1	viability after 15 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.3705507968668973	[1521]	[605,508]	2	hSpCas9	negative selection	1272401
44275604	44275627	11	+	26627737	RPE1	viability after 15 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.4045696762544961	[1090]	[294,517]	2	hSpCas9	negative selection	1272402
44309974	44309997	11	+	26627737	RPE1	viability after 15 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.03797687784368131	[2296]	[801,536]	0	hSpCas9	negative selection	1272403
44310004	44310027	11	+	26627737	RPE1	viability after 15 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	2.407221286958621	[63]	[65,124]	9	hSpCas9	negative selection	1272404
44264931	44264954	11	-	26627737	RPE1	viability after 18 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.10983884787255133	[970]	[246,320]	0	hSpCas9	negative selection	1354714
44264945	44264968	11	+	26627737	RPE1	viability after 18 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	1.3216589044593612	[676]	[548,357]	7	hSpCas9	negative selection	1354715
44275572	44275595	11	-	26627737	RPE1	viability after 18 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.19848567168808007	[1521]	[436,507]	1	hSpCas9	negative selection	1354716
44275604	44275627	11	+	26627737	RPE1	viability after 18 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.05461486337118199	[1090]	[284,327]	0	hSpCas9	negative selection	1354717
44309974	44309997	11	+	26627737	RPE1	viability after 18 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.46739825647473165	[2296]	[370,530]	-3	hSpCas9	negative selection	1354718
44310004	44310027	11	+	26627737	RPE1	viability after 18 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	3.534173858331851	[63]	[260,134]	9	hSpCas9	negative selection	1354719
44264931	44264954	11	-	26627737	HeLa	viability after 8 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	1.3247374729619694	[303]	[401,311,297]	8	hSpCas9	negative selection	1437029
44264945	44264968	11	+	26627737	HeLa	viability after 8 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.4978541127240378	[326]	[285,215,124]	4	hSpCas9	negative selection	1437030
44275572	44275595	11	-	26627737	HeLa	viability after 8 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.9308569529569146	[691]	[214,151,121]	-7	hSpCas9	negative selection	1437031
44275604	44275627	11	+	26627737	HeLa	viability after 8 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.3760861108405491	[431]	[202,351,172]	3	hSpCas9	negative selection	1437032
44309974	44309997	11	+	26627737	HeLa	viability after 8 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.16388456709066923	[1366]	[421,676,473]	-1	hSpCas9	negative selection	1437033
44310004	44310027	11	+	26627737	HeLa	viability after 8 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	8.118838726268416	[0]	[140,189,41]	9	hSpCas9	negative selection	1437034
44264931	44264954	11	-	26627737	HeLa	viability after 12 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	1.0566866844323448	[303]	[356,230,201]	7	hSpCas9	negative selection	1519344
44264945	44264968	11	+	26627737	HeLa	viability after 12 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	-0.6091569711746927	[326]	[13,150,91]	-5	hSpCas9	negative selection	1519345
44275572	44275595	11	-	26627737	HeLa	viability after 12 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.5249681110155149	[691]	[128,247,211]	-5	hSpCas9	negative selection	1519346
44275604	44275627	11	+	26627737	HeLa	viability after 12 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-1.7684215361173277	[431]	[8,117,21]	-9	hSpCas9	negative selection	1519347
44309974	44309997	11	+	26627737	HeLa	viability after 12 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.7579693594159593	[1366]	[370,411,211]	-6	hSpCas9	negative selection	1519348
44310004	44310027	11	+	26627737	HeLa	viability after 12 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	6.744993309025126	[0]	[27,67,33]	9	hSpCas9	negative selection	1519349
44264931	44264954	11	-	26627737	HeLa	viability after 15 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	1.169527568412905	[303]	[203,511,106]	8	hSpCas9	negative selection	1601659
44264945	44264968	11	+	26627737	HeLa	viability after 15 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.30752362970903613	[326]	[202,110,180]	2	hSpCas9	negative selection	1601660
44275572	44275595	11	-	26627737	HeLa	viability after 15 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.31384834780979637	[691]	[233,216,228]	-3	hSpCas9	negative selection	1601661
44275604	44275627	11	+	26627737	HeLa	viability after 15 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.9105493800417447	[431]	[82,101,95]	-7	hSpCas9	negative selection	1601662
44309974	44309997	11	+	26627737	HeLa	viability after 15 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-1.3464384720791893	[1366]	[95,332,229]	-8	hSpCas9	negative selection	1601663
44310004	44310027	11	+	26627737	HeLa	viability after 15 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	7.927499126975421	[0]	[104,59,134]	9	hSpCas9	negative selection	1601664
44264931	44264954	11	-	26627737	HeLa	viability after 18 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	1.2072967921467948	[303]	[151,422,106]	8	hSpCas9	negative selection	1683974
44264945	44264968	11	+	26627737	HeLa	viability after 18 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.35736589477170977	[326]	[144,94,180]	3	hSpCas9	negative selection	1683975
44275572	44275595	11	-	26627737	HeLa	viability after 18 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.30976889885437164	[691]	[157,179,228]	-3	hSpCas9	negative selection	1683976
44275604	44275627	11	+	26627737	HeLa	viability after 18 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.9125897821884292	[431]	[50,89,95]	-7	hSpCas9	negative selection	1683977
44309974	44309997	11	+	26627737	HeLa	viability after 18 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-1.3981861267095181	[1366]	[49,274,229]	-8	hSpCas9	negative selection	1683978
44310004	44310027	11	+	26627737	HeLa	viability after 18 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	7.912478002560659	[0]	[68,48,134]	9	hSpCas9	negative selection	1683979
44264931	44264954	11	-	26627737	HCT116	viability after 6 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.6224102982306879	[309]	[201,4]	3	hSpCas9	negative selection	1766289
44264945	44264968	11	+	26627737	HCT116	viability after 6 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	1.9339980908771672	[578]	[283,382]	8	hSpCas9	negative selection	1766290
44275572	44275595	11	-	26627737	HCT116	viability after 6 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.6624065861465046	[577]	[186,119]	3	hSpCas9	negative selection	1766291
44275604	44275627	11	+	26627737	HCT116	viability after 6 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.47403622237132814	[706]	[99,68]	-3	hSpCas9	negative selection	1766292
44309974	44309997	11	+	26627737	HCT116	viability after 6 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	1.3421145291959813	[1300]	[591,477]	7	hSpCas9	negative selection	1766293
44310004	44310027	11	+	26627737	HCT116	viability after 6 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	1.1686406277935995	[656]	[52,330]	6	hSpCas9	negative selection	1766294
44264931	44264954	11	-	26627737	HCT116	viability after 8 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.05822072895293309	[345]	[87,261,242]	0	hSpCas9	negative selection	1848604
44264945	44264968	11	+	26627737	HCT116	viability after 8 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	-0.34383383385461985	[410]	[169,170,193]	-4	hSpCas9	negative selection	1848605
44275572	44275595	11	-	26627737	HCT116	viability after 8 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.21867981179843898	[507]	[369,364,243]	2	hSpCas9	negative selection	1848606
44275604	44275627	11	+	26627737	HCT116	viability after 8 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.06595664443509817	[313]	[243,162,137]	0	hSpCas9	negative selection	1848607
44309974	44309997	11	+	26627737	HCT116	viability after 8 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.06009321204672369	[878]	[561,458,494]	0	hSpCas9	negative selection	1848608
44310004	44310027	11	+	26627737	HCT116	viability after 8 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	0.2830421630212452	[162]	[114,106,105]	3	hSpCas9	negative selection	1848609
44264931	44264954	11	-	26627737	HCT116	viability after 9 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	1.1676048900397415	[309]	[133,226]	7	hSpCas9	negative selection	1930919
44264945	44264968	11	+	26627737	HCT116	viability after 9 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.49318863933356527	[578]	[268,176]	3	hSpCas9	negative selection	1930920
44275572	44275595	11	-	26627737	HCT116	viability after 9 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-1.1555838546481272	[577]	[37,93]	-7	hSpCas9	negative selection	1930921
44275604	44275627	11	+	26627737	HCT116	viability after 9 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.9065883045036388	[706]	[435,288]	6	hSpCas9	negative selection	1930922
44309974	44309997	11	+	26627737	HCT116	viability after 9 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	1.411333606051731	[1300]	[737,1070]	8	hSpCas9	negative selection	1930923
44310004	44310027	11	+	26627737	HCT116	viability after 9 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	0.11043669579611537	[656]	[323,82]	0	hSpCas9	negative selection	1930924
44264931	44264954	11	-	26627737	HCT116	viability after 12 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.1356941000395784	[345]	[197,139,259]	1	hSpCas9	negative selection	2013234
44264945	44264968	11	+	26627737	HCT116	viability after 12 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	-0.3249862724447663	[410]	[108,260,154]	-3	hSpCas9	negative selection	2013235
44275572	44275595	11	-	26627737	HCT116	viability after 12 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.24204398082224765	[507]	[346,296,299]	2	hSpCas9	negative selection	2013236
44275604	44275627	11	+	26627737	HCT116	viability after 12 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.2946955538238543	[313]	[234,186,181]	3	hSpCas9	negative selection	2013237
44309974	44309997	11	+	26627737	HCT116	viability after 12 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.044352274909627676	[878]	[600,470,345]	0	hSpCas9	negative selection	2013238
44310004	44310027	11	+	26627737	HCT116	viability after 12 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	0.38596172309279086	[162]	[47,176,117]	4	hSpCas9	negative selection	2013239
44264931	44264954	11	-	26627737	HCT116	viability after 15 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.3166000074368023	[345]	[324,192,233]	3	hSpCas9	negative selection	2095549
44264945	44264968	11	+	26627737	HCT116	viability after 15 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.1473763634676643	[410]	[114,352,297]	1	hSpCas9	negative selection	2095550
44275572	44275595	11	-	26627737	HCT116	viability after 15 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.35396547846123605	[507]	[383,283,450]	3	hSpCas9	negative selection	2095551
44275604	44275627	11	+	26627737	HCT116	viability after 15 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.4713260577353199	[313]	[265,113,27]	-5	hSpCas9	negative selection	2095552
44309974	44309997	11	+	26627737	HCT116	viability after 15 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.277977621643664	[878]	[541,363,358]	-3	hSpCas9	negative selection	2095553
44310004	44310027	11	+	26627737	HCT116	viability after 15 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	0.6563669934452877	[162]	[141,156,142]	6	hSpCas9	negative selection	2095554
44264931	44264954	11	-	26627737	HCT116	viability after 18 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.44858158314446284	[345]	[215,171,303]	4	hSpCas9	negative selection	2177864
44264945	44264968	11	+	26627737	HCT116	viability after 18 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.05557347737859314	[410]	[196,111,321]	0	hSpCas9	negative selection	2177865
44275572	44275595	11	-	26627737	HCT116	viability after 18 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.43149734508582416	[507]	[509,211,276]	3	hSpCas9	negative selection	2177866
44275604	44275627	11	+	26627737	HCT116	viability after 18 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.5119331777403596	[313]	[286,267,84]	4	hSpCas9	negative selection	2177867
44309974	44309997	11	+	26627737	HCT116	viability after 18 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.2686958328936433	[878]	[247,371,440]	-2	hSpCas9	negative selection	2177868
44310004	44310027	11	+	26627737	HCT116	viability after 18 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	-0.2592161394921051	[162]	[79,55,61]	-2	hSpCas9	negative selection	2177869
44309896	44309919	11	-	24336569	HL60	viability	TCGGCCGCCGCCAAAGCACAGGG	ALX4	ENSG00000052850	-0.26183084879285534	[233]	[412]	-2	hSpCas9	negative selection	2247599
44309915	44309938	11	-	24336569	HL60	viability	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	1.6864075351230248	[126]	[864]	9	hSpCas9	negative selection	2247600
44309928	44309951	11	+	24336569	HL60	viability	TGTGCCGAACTTGTCGCCTCCGG	ALX4	ENSG00000052850	-0.17949006468002848	[920]	[1720]	-1	hSpCas9	negative selection	2247601
44309974	44309997	11	-	24336569	HL60	viability	CCGGTGTCGCAGAGTCGGGAGGG	ALX4	ENSG00000052850	-0.26894007579710866	[795]	[1397]	-2	hSpCas9	negative selection	2247602
44309979	44310002	11	-	24336569	HL60	viability	ACAGCCCGGTGTCGCAGAGTCGG	ALX4	ENSG00000052850	-0.6379599460479918	[413]	[562]	-5	hSpCas9	negative selection	2247603
44309985	44310008	11	+	24336569	HL60	viability	CTGCGACACCGGGCTGTAGTAGG	ALX4	ENSG00000052850	1.3196112456274238	[304]	[1610]	8	hSpCas9	negative selection	2247604
44309993	44310016	11	-	24336569	HL60	viability	CATGGACGCCTACTACAGCCCGG	ALX4	ENSG00000052850	-0.4780348512489322	[413]	[628]	-4	hSpCas9	negative selection	2247605
44310000	44310023	11	+	24336569	HL60	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-1.2254034493605062	[336]	[304]	-8	hSpCas9	negative selection	2247606
44310011	44310034	11	-	24336569	HL60	viability	CGAGTCGCCGGCCGCTGCCATGG	ALX4	ENSG00000052850	-0.532008602297456	[616]	[902]	-5	hSpCas9	negative selection	2247607
44310023	44310046	11	-	24336569	HL60	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.6403484689832232	[698]	[948]	-5	hSpCas9	negative selection	2247608
44309896	44309919	11	-	24336569	KBM7	viability	TCGGCCGCCGCCAAAGCACAGGG	ALX4	ENSG00000052850	0.7188313207171928	[136]	[614]	6	hSpCas9	negative selection	2314776
44309915	44309938	11	-	24336569	KBM7	viability	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	-0.5176576322850229	[463]	[883]	-4	hSpCas9	negative selection	2314777
44309928	44309951	11	+	24336569	KBM7	viability	TGTGCCGAACTTGTCGCCTCCGG	ALX4	ENSG00000052850	0.4327819163048212	[621]	[2289]	4	hSpCas9	negative selection	2314778
44309974	44309997	11	-	24336569	KBM7	viability	CCGGTGTCGCAGAGTCGGGAGGG	ALX4	ENSG00000052850	-0.15858659761596727	[637]	[1558]	-1	hSpCas9	negative selection	2314779
44309979	44310002	11	-	24336569	KBM7	viability	ACAGCCCGGTGTCGCAGAGTCGG	ALX4	ENSG00000052850	0.41325805577949204	[260]	[947]	4	hSpCas9	negative selection	2314780
44309985	44310008	11	+	24336569	KBM7	viability	CTGCGACACCGGGCTGTAGTAGG	ALX4	ENSG00000052850	1.8366292323893212	[92]	[905]	9	hSpCas9	negative selection	2314781
44309993	44310016	11	-	24336569	KBM7	viability	CATGGACGCCTACTACAGCCCGG	ALX4	ENSG00000052850	0.11501549114381904	[259]	[767]	1	hSpCas9	negative selection	2314782
44310000	44310023	11	+	24336569	KBM7	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.4430910466013054	[160]	[596]	4	hSpCas9	negative selection	2314783
44310011	44310034	11	-	24336569	KBM7	viability	CGAGTCGCCGGCCGCTGCCATGG	ALX4	ENSG00000052850	0.4062000626000737	[331]	[1199]	4	hSpCas9	negative selection	2314784
44310023	44310046	11	-	24336569	KBM7	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.8791158912459324	[422]	[2121]	7	hSpCas9	negative selection	2314785
44299616	44299639	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCAAAATGCTGGGATTACGGG	ALX4	ENSG00000052850	0.20161513672590614	[46,60]	[10,15]	1	dCas9-VP64	positive selection	2475362
44299616	44299639	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCAAAATGCTGGGATTACGGG	ALX4	ENSG00000052850	-0.42275240861415275	[53,301]	[32,50]	-4	dCas9-VP64	positive selection	2570617
44309683	44309706	11	-	27260157	DLD1	viability	CCGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	-0.182945153654546	[]	[]	-1	hSpCas9	negative selection	2577207
44309993	44310016	11	-	27260157	DLD1	viability	CATGGACGCCTACTACAGCCCGG	ALX4	ENSG00000052850	0.425339641227808	[]	[]	7	hSpCas9	negative selection	2579693
44309849	44309872	11	+	27260157	DLD1	viability	CCTGCTGCCCAGCGCCGTAACGG	ALX4	ENSG00000052850	-0.109415565155881	[]	[]	-1	hSpCas9	negative selection	2580894
44309985	44310008	11	+	27260157	DLD1	viability	CTGCGACACCGGGCTGTAGTAGG	ALX4	ENSG00000052850	0.00519707184870837	[]	[]	0	hSpCas9	negative selection	2582308
44309862	44309885	11	+	27260157	DLD1	viability	GCCGTAACGGGCCCGGCTCTTGG	ALX4	ENSG00000052850	0.857892428050316	[]	[]	9	hSpCas9	negative selection	2583540
44309944	44309967	11	+	27260157	DLD1	viability	CCTCCGGGAAATGCCCTAAAAGG	ALX4	ENSG00000052850	0.463876086819195	[]	[]	8	hSpCas9	negative selection	2584029
44309896	44309919	11	-	27260157	DLD1	viability	TCGGCCGCCGCCAAAGCACAGGG	ALX4	ENSG00000052850	0.542786896181573	[]	[]	8	hSpCas9	negative selection	2585508
44310023	44310046	11	-	27260157	DLD1	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	1.14872451363458	[]	[]	9	hSpCas9	negative selection	2586128
44309979	44310002	11	-	27260157	DLD1	viability	ACAGCCCGGTGTCGCAGAGTCGG	ALX4	ENSG00000052850	-0.358669355536717	[]	[]	-3	hSpCas9	negative selection	2604559
44309974	44309997	11	-	27260157	DLD1	viability	CCGGTGTCGCAGAGTCGGGAGGG	ALX4	ENSG00000052850	-0.385369496772644	[]	[]	-3	hSpCas9	negative selection	2607661
44309900	44309923	11	+	27260157	DLD1	viability	GTGCTTTGGCGGCGGCCGACAGG	ALX4	ENSG00000052850	0.649001626142854	[]	[]	8	hSpCas9	negative selection	2608740
44310000	44310023	11	+	27260157	DLD1	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.952492238735501	[]	[]	-7	hSpCas9	negative selection	2611753
44309928	44309951	11	+	27260157	DLD1	viability	TGTGCCGAACTTGTCGCCTCCGG	ALX4	ENSG00000052850	0.628928140432433	[]	[]	8	hSpCas9	negative selection	2614339
44309974	44309997	11	+	27260157	DLD1	viability	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.414704898010286	[]	[]	4	hSpCas9	negative selection	2617353
44309915	44309938	11	-	27260157	DLD1	viability	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	0.64354986522944	[]	[]	8	hSpCas9	negative selection	2618128
44309863	44309886	11	-	27260157	DLD1	viability	GCCAAGAGCCGGGCCCGTTACGG	ALX4	ENSG00000052850	-0.0750294353009321	[]	[]	0	hSpCas9	negative selection	2621073
44309932	44309955	11	-	27260157	DLD1	viability	TTTCCCGGAGGCGACAAGTTCGG	ALX4	ENSG00000052850	1.18476962465143	[]	[]	9	hSpCas9	negative selection	2644833
44309849	44309872	11	-	27260157	DLD1	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.211468232764163	[]	[]	3	hSpCas9	negative selection	2646148
44310011	44310034	11	-	27260157	DLD1	viability	CGAGTCGCCGGCCGCTGCCATGG	ALX4	ENSG00000052850	1.03048314820535	[]	[]	9	hSpCas9	negative selection	2646959
44309695	44309718	11	+	27260157	DLD1	viability	TAAAGATGCGGTTGCGCGGGCGG	ALX4	ENSG00000052850	-0.984328253071195	[]	[]	-7	hSpCas9	negative selection	2649582
44309683	44309706	11	-	27260157	HT1080	viability	CCGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.326438372647105	[]	[]	3	hSpCas9	negative selection	2653337
44309993	44310016	11	-	27260157	HT1080	viability	CATGGACGCCTACTACAGCCCGG	ALX4	ENSG00000052850	1.05766508137283	[]	[]	8	hSpCas9	negative selection	2655823
44309849	44309872	11	+	27260157	HT1080	viability	CCTGCTGCCCAGCGCCGTAACGG	ALX4	ENSG00000052850	0.264447796865406	[]	[]	2	hSpCas9	negative selection	2657024
44309985	44310008	11	+	27260157	HT1080	viability	CTGCGACACCGGGCTGTAGTAGG	ALX4	ENSG00000052850	0.0157998515165752	[]	[]	0	hSpCas9	negative selection	2658438
44309862	44309885	11	+	27260157	HT1080	viability	GCCGTAACGGGCCCGGCTCTTGG	ALX4	ENSG00000052850	0.410551758321936	[]	[]	4	hSpCas9	negative selection	2659670
44309944	44309967	11	+	27260157	HT1080	viability	CCTCCGGGAAATGCCCTAAAAGG	ALX4	ENSG00000052850	0.651584141090367	[]	[]	5	hSpCas9	negative selection	2660159
44309896	44309919	11	-	27260157	HT1080	viability	TCGGCCGCCGCCAAAGCACAGGG	ALX4	ENSG00000052850	0.523090554506415	[]	[]	4	hSpCas9	negative selection	2661638
44310023	44310046	11	-	27260157	HT1080	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-2.08446864823132	[]	[]	-9	hSpCas9	negative selection	2662258
44309979	44310002	11	-	27260157	HT1080	viability	ACAGCCCGGTGTCGCAGAGTCGG	ALX4	ENSG00000052850	0.181689439500211	[]	[]	1	hSpCas9	negative selection	2680689
44309974	44309997	11	-	27260157	HT1080	viability	CCGGTGTCGCAGAGTCGGGAGGG	ALX4	ENSG00000052850	-0.0631705407971905	[]	[]	0	hSpCas9	negative selection	2683791
44309900	44309923	11	+	27260157	HT1080	viability	GTGCTTTGGCGGCGGCCGACAGG	ALX4	ENSG00000052850	1.39557221927761	[]	[]	9	hSpCas9	negative selection	2684870
44310000	44310023	11	+	27260157	HT1080	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.545918382514297	[]	[]	-7	hSpCas9	negative selection	2687883
44309928	44309951	11	+	27260157	HT1080	viability	TGTGCCGAACTTGTCGCCTCCGG	ALX4	ENSG00000052850	0.616964750080009	[]	[]	5	hSpCas9	negative selection	2690469
44309974	44309997	11	+	27260157	HT1080	viability	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.344024092321313	[]	[]	3	hSpCas9	negative selection	2693483
44309915	44309938	11	-	27260157	HT1080	viability	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	-0.415021876557497	[]	[]	-7	hSpCas9	negative selection	2694258
44309863	44309886	11	-	27260157	HT1080	viability	GCCAAGAGCCGGGCCCGTTACGG	ALX4	ENSG00000052850	-0.0533179789562792	[]	[]	0	hSpCas9	negative selection	2697203
44309932	44309955	11	-	27260157	HT1080	viability	TTTCCCGGAGGCGACAAGTTCGG	ALX4	ENSG00000052850	1.64889936494529	[]	[]	9	hSpCas9	negative selection	2720963
44309849	44309872	11	-	27260157	HT1080	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.375165348281543	[]	[]	3	hSpCas9	negative selection	2722278
44310011	44310034	11	-	27260157	HT1080	viability	CGAGTCGCCGGCCGCTGCCATGG	ALX4	ENSG00000052850	0.734322190515185	[]	[]	6	hSpCas9	negative selection	2723089
44309695	44309718	11	+	27260157	HT1080	viability	TAAAGATGCGGTTGCGCGGGCGG	ALX4	ENSG00000052850	-1.02314737330954	[]	[]	-8	hSpCas9	negative selection	2725712
44309683	44309706	11	-	27260157	MKN45	viability	CCGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.300504079324992	[]	[]	5	hSpCas9	negative selection	2729467
44309993	44310016	11	-	27260157	MKN45	viability	CATGGACGCCTACTACAGCCCGG	ALX4	ENSG00000052850	-0.0333459942842881	[]	[]	0	hSpCas9	negative selection	2731953
44309849	44309872	11	+	27260157	MKN45	viability	CCTGCTGCCCAGCGCCGTAACGG	ALX4	ENSG00000052850	0.776488638716482	[]	[]	7	hSpCas9	negative selection	2733154
44309985	44310008	11	+	27260157	MKN45	viability	CTGCGACACCGGGCTGTAGTAGG	ALX4	ENSG00000052850	-0.407221984429271	[]	[]	-1	hSpCas9	negative selection	2734568
44309862	44309885	11	+	27260157	MKN45	viability	GCCGTAACGGGCCCGGCTCTTGG	ALX4	ENSG00000052850	0.467079632143934	[]	[]	6	hSpCas9	negative selection	2735800
44309944	44309967	11	+	27260157	MKN45	viability	CCTCCGGGAAATGCCCTAAAAGG	ALX4	ENSG00000052850	0.474274955493288	[]	[]	6	hSpCas9	negative selection	2736289
44309896	44309919	11	-	27260157	MKN45	viability	TCGGCCGCCGCCAAAGCACAGGG	ALX4	ENSG00000052850	-0.559974390884454	[]	[]	-6	hSpCas9	negative selection	2737768
44310023	44310046	11	-	27260157	MKN45	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.878027811245997	[]	[]	8	hSpCas9	negative selection	2738388
44309979	44310002	11	-	27260157	MKN45	viability	ACAGCCCGGTGTCGCAGAGTCGG	ALX4	ENSG00000052850	0.392715144045161	[]	[]	6	hSpCas9	negative selection	2756819
44309974	44309997	11	-	27260157	MKN45	viability	CCGGTGTCGCAGAGTCGGGAGGG	ALX4	ENSG00000052850	-0.347642963503978	[]	[]	-1	hSpCas9	negative selection	2759921
44309900	44309923	11	+	27260157	MKN45	viability	GTGCTTTGGCGGCGGCCGACAGG	ALX4	ENSG00000052850	0.889090071770894	[]	[]	8	hSpCas9	negative selection	2761000
44310000	44310023	11	+	27260157	MKN45	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-1.76772364474501	[]	[]	-9	hSpCas9	negative selection	2764013
44309928	44309951	11	+	27260157	MKN45	viability	TGTGCCGAACTTGTCGCCTCCGG	ALX4	ENSG00000052850	1.14802961093446	[]	[]	8	hSpCas9	negative selection	2766599
44309974	44309997	11	+	27260157	MKN45	viability	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.0301570984878262	[]	[]	0	hSpCas9	negative selection	2769613
44309915	44309938	11	-	27260157	MKN45	viability	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	-0.0209899146019509	[]	[]	0	hSpCas9	negative selection	2770388
44309863	44309886	11	-	27260157	MKN45	viability	GCCAAGAGCCGGGCCCGTTACGG	ALX4	ENSG00000052850	-0.741277603538565	[]	[]	-7	hSpCas9	negative selection	2773333
44309932	44309955	11	-	27260157	MKN45	viability	TTTCCCGGAGGCGACAAGTTCGG	ALX4	ENSG00000052850	-0.0911114436314051	[]	[]	0	hSpCas9	negative selection	2797093
44309849	44309872	11	-	27260157	MKN45	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.420991134444251	[]	[]	6	hSpCas9	negative selection	2798408
44310011	44310034	11	-	27260157	MKN45	viability	CGAGTCGCCGGCCGCTGCCATGG	ALX4	ENSG00000052850	0.703041046013982	[]	[]	7	hSpCas9	negative selection	2799219
44309695	44309718	11	+	27260157	MKN45	viability	TAAAGATGCGGTTGCGCGGGCGG	ALX4	ENSG00000052850	0.198994614732889	[]	[]	5	hSpCas9	negative selection	2801842
44309683	44309706	11	-	27260157	RKO	viability	CCGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	1.01637042545845	[]	[]	9	hSpCas9	negative selection	2805597
44309993	44310016	11	-	27260157	RKO	viability	CATGGACGCCTACTACAGCCCGG	ALX4	ENSG00000052850	0.559020639768316	[]	[]	3	hSpCas9	negative selection	2808083
44309849	44309872	11	+	27260157	RKO	viability	CCTGCTGCCCAGCGCCGTAACGG	ALX4	ENSG00000052850	0.937526424885863	[]	[]	8	hSpCas9	negative selection	2809284
44309985	44310008	11	+	27260157	RKO	viability	CTGCGACACCGGGCTGTAGTAGG	ALX4	ENSG00000052850	0.255105593510075	[]	[]	1	hSpCas9	negative selection	2810698
44309862	44309885	11	+	27260157	RKO	viability	GCCGTAACGGGCCCGGCTCTTGG	ALX4	ENSG00000052850	0.919607674546653	[]	[]	8	hSpCas9	negative selection	2811930
44309944	44309967	11	+	27260157	RKO	viability	CCTCCGGGAAATGCCCTAAAAGG	ALX4	ENSG00000052850	0.281506650158986	[]	[]	1	hSpCas9	negative selection	2812419
44309896	44309919	11	-	27260157	RKO	viability	TCGGCCGCCGCCAAAGCACAGGG	ALX4	ENSG00000052850	0.593343022475964	[]	[]	3	hSpCas9	negative selection	2813898
44310023	44310046	11	-	27260157	RKO	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.194812142769614	[]	[]	1	hSpCas9	negative selection	2814518
44309979	44310002	11	-	27260157	RKO	viability	ACAGCCCGGTGTCGCAGAGTCGG	ALX4	ENSG00000052850	0.254705061722795	[]	[]	1	hSpCas9	negative selection	2832949
44309974	44309997	11	-	27260157	RKO	viability	CCGGTGTCGCAGAGTCGGGAGGG	ALX4	ENSG00000052850	-0.476296586779895	[]	[]	-6	hSpCas9	negative selection	2836051
44309900	44309923	11	+	27260157	RKO	viability	GTGCTTTGGCGGCGGCCGACAGG	ALX4	ENSG00000052850	1.1390654929898	[]	[]	9	hSpCas9	negative selection	2837130
44310000	44310023	11	+	27260157	RKO	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.00646582720227954	[]	[]	0	hSpCas9	negative selection	2840143
44309928	44309951	11	+	27260157	RKO	viability	TGTGCCGAACTTGTCGCCTCCGG	ALX4	ENSG00000052850	1.21261833064077	[]	[]	9	hSpCas9	negative selection	2842729
44309974	44309997	11	+	27260157	RKO	viability	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.916771152183835	[]	[]	8	hSpCas9	negative selection	2845743
44309915	44309938	11	-	27260157	RKO	viability	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	0.474672857685536	[]	[]	2	hSpCas9	negative selection	2846518
44309863	44309886	11	-	27260157	RKO	viability	GCCAAGAGCCGGGCCCGTTACGG	ALX4	ENSG00000052850	-0.937904009204887	[]	[]	-8	hSpCas9	negative selection	2849463
44309932	44309955	11	-	27260157	RKO	viability	TTTCCCGGAGGCGACAAGTTCGG	ALX4	ENSG00000052850	-0.234914586159629	[]	[]	-1	hSpCas9	negative selection	2873223
44309849	44309872	11	-	27260157	RKO	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.61559578427023	[]	[]	3	hSpCas9	negative selection	2874538
44310011	44310034	11	-	27260157	RKO	viability	CGAGTCGCCGGCCGCTGCCATGG	ALX4	ENSG00000052850	0.732844049843082	[]	[]	8	hSpCas9	negative selection	2875349
44309695	44309718	11	+	27260157	RKO	viability	TAAAGATGCGGTTGCGCGGGCGG	ALX4	ENSG00000052850	-0.727545840955085	[]	[]	-7	hSpCas9	negative selection	2877972
44309683	44309706	11	-	27260157	SF268	viability	CCGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	-0.305697029253219	[]	[]	-2	hSpCas9	negative selection	2881727
44309993	44310016	11	-	27260157	SF268	viability	CATGGACGCCTACTACAGCCCGG	ALX4	ENSG00000052850	-0.217735934591318	[]	[]	-2	hSpCas9	negative selection	2884213
44309849	44309872	11	+	27260157	SF268	viability	CCTGCTGCCCAGCGCCGTAACGG	ALX4	ENSG00000052850	-0.0418838382099293	[]	[]	0	hSpCas9	negative selection	2885414
44309985	44310008	11	+	27260157	SF268	viability	CTGCGACACCGGGCTGTAGTAGG	ALX4	ENSG00000052850	-0.0198990126003075	[]	[]	0	hSpCas9	negative selection	2886828
44309862	44309885	11	+	27260157	SF268	viability	GCCGTAACGGGCCCGGCTCTTGG	ALX4	ENSG00000052850	-0.0332903792723848	[]	[]	0	hSpCas9	negative selection	2888060
44309944	44309967	11	+	27260157	SF268	viability	CCTCCGGGAAATGCCCTAAAAGG	ALX4	ENSG00000052850	0.245122058417401	[]	[]	3	hSpCas9	negative selection	2888549
44309896	44309919	11	-	27260157	SF268	viability	TCGGCCGCCGCCAAAGCACAGGG	ALX4	ENSG00000052850	0.233959719805352	[]	[]	3	hSpCas9	negative selection	2890028
44310023	44310046	11	-	27260157	SF268	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.575500652262734	[]	[]	8	hSpCas9	negative selection	2890648
44309979	44310002	11	-	27260157	SF268	viability	ACAGCCCGGTGTCGCAGAGTCGG	ALX4	ENSG00000052850	0.0670950111550559	[]	[]	0	hSpCas9	negative selection	2909079
44309974	44309997	11	-	27260157	SF268	viability	CCGGTGTCGCAGAGTCGGGAGGG	ALX4	ENSG00000052850	-0.431095010927229	[]	[]	-3	hSpCas9	negative selection	2912181
44309900	44309923	11	+	27260157	SF268	viability	GTGCTTTGGCGGCGGCCGACAGG	ALX4	ENSG00000052850	0.618813520954353	[]	[]	8	hSpCas9	negative selection	2913260
44310000	44310023	11	+	27260157	SF268	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-1.20497983077619	[]	[]	-7	hSpCas9	negative selection	2916273
44309928	44309951	11	+	27260157	SF268	viability	TGTGCCGAACTTGTCGCCTCCGG	ALX4	ENSG00000052850	1.01594441329116	[]	[]	9	hSpCas9	negative selection	2918859
44309974	44309997	11	+	27260157	SF268	viability	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.00329358278756837	[]	[]	0	hSpCas9	negative selection	2921873
44309915	44309938	11	-	27260157	SF268	viability	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	-0.428593451170693	[]	[]	-3	hSpCas9	negative selection	2922648
44309863	44309886	11	-	27260157	SF268	viability	GCCAAGAGCCGGGCCCGTTACGG	ALX4	ENSG00000052850	0.166177326096826	[]	[]	0	hSpCas9	negative selection	2925593
44309932	44309955	11	-	27260157	SF268	viability	TTTCCCGGAGGCGACAAGTTCGG	ALX4	ENSG00000052850	0.375372042490867	[]	[]	4	hSpCas9	negative selection	2949353
44309849	44309872	11	-	27260157	SF268	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.172568700916474	[]	[]	0	hSpCas9	negative selection	2950668
44310011	44310034	11	-	27260157	SF268	viability	CGAGTCGCCGGCCGCTGCCATGG	ALX4	ENSG00000052850	0.772724002837811	[]	[]	8	hSpCas9	negative selection	2951479
44309695	44309718	11	+	27260157	SF268	viability	TAAAGATGCGGTTGCGCGGGCGG	ALX4	ENSG00000052850	-1.22477969957736	[]	[]	-7	hSpCas9	negative selection	2954102
44310001	44310024	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.13304396176020122	[3,3]	[4,0]	-2	hSpCas9	positive selection	2970041
44309915	44309938	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	0.0001603929819781469	[4,4]	[4,2]	0	hSpCas9	positive selection	2970042
44310001	44310024	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.28308114882376023	[3,3]	[4,0]	-4	hSpCas9	positive selection	3037899
44309915	44309938	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	0.6130101854267271	[4,4]	[5,4]	8	hSpCas9	positive selection	3037900
44267578	44267601		+	24336571	A375	resistance to PLX after 7 days	ACGCTCCCGCTTCCTCCACTTGG	ALX4	ENSG00000052850	-0.18773368055563944	[21,18]	[17,17]	-6	hSpCas9	positive selection	3115415
44275601	44275624		+	24336571	A375	resistance to PLX after 7 days	ATCCCCACAGTGTCAGAGTCAGG	ALX4	ENSG00000052850	0.3344024801400266	[8,9]	[12,11]	8	hSpCas9	positive selection	3115426
44267493	44267516		-	24336571	A375	resistance to PLX after 7 days	CCGAGCTGAGAACTACGCCCAGG	ALX4	ENSG00000052850	-0.05499874651937264	[9,10]	[8,10]	-1	hSpCas9	positive selection	3115437
44275388	44275411		+	24336571	A375	resistance to PLX after 7 days	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.02553357824320651	[16,18]	[20,14]	0	hSpCas9	positive selection	3115449
44267578	44267601		+	24336571	A375	resistance to PLX after 14 days	ACGCTCCCGCTTCCTCCACTTGG	ALX4	ENSG00000052850	-0.4603931471538296	[25,18]	[5,8]	-5	hSpCas9	positive selection	3173208
44275601	44275624		+	24336571	A375	resistance to PLX after 14 days	ATCCCCACAGTGTCAGAGTCAGG	ALX4	ENSG00000052850	1.2318559812311753	[10,6]	[10,8]	8	hSpCas9	positive selection	3173219
44267493	44267516		-	24336571	A375	resistance to PLX after 14 days	CCGAGCTGAGAACTACGCCCAGG	ALX4	ENSG00000052850	0.16232140211441667	[9,14]	[7,3]	1	hSpCas9	positive selection	3173230
44275388	44275411		+	24336571	A375	resistance to PLX after 14 days	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.17353839721427244	[18,19]	[7,6]	-2	hSpCas9	positive selection	3173242
44267578	44267601		+	24336571	A375	viability after 7 days	ACGCTCCCGCTTCCTCCACTTGG	ALX4	ENSG00000052850	0.3854801665988314	[16]	[21,18]	6	hSpCas9	negative selection	3231001
44275601	44275624		+	24336571	A375	viability after 7 days	ATCCCCACAGTGTCAGAGTCAGG	ALX4	ENSG00000052850	0.37829590699501275	[7]	[8,9]	6	hSpCas9	negative selection	3231012
44267493	44267516		-	24336571	A375	viability after 7 days	CCGAGCTGAGAACTACGCCCAGG	ALX4	ENSG00000052850	-0.2688573262646475	[13]	[9,10]	-4	hSpCas9	negative selection	3231023
44275388	44275411		+	24336571	A375	viability after 7 days	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.29235285320429016	[15]	[16,18]	4	hSpCas9	negative selection	3231035
44267578	44267601		+	24336571	A375	viability after 14 days	ACGCTCCCGCTTCCTCCACTTGG	ALX4	ENSG00000052850	0.4912930884186307	[16]	[25,18]	6	hSpCas9	negative selection	3288794
44275601	44275624		+	24336571	A375	viability after 14 days	ATCCCCACAGTGTCAGAGTCAGG	ALX4	ENSG00000052850	0.25260423946745303	[7]	[10,6]	3	hSpCas9	negative selection	3288805
44267493	44267516		-	24336571	A375	viability after 14 days	CCGAGCTGAGAACTACGCCCAGG	ALX4	ENSG00000052850	-0.049294934026970764	[13]	[9,14]	0	hSpCas9	negative selection	3288816
44275388	44275411		+	24336571	A375	viability after 14 days	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.38902469917318794	[15]	[18,19]	5	hSpCas9	negative selection	3288828
44310023	44310046	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	1.6510808568831374	[169,170]	[0,5]	6	hSpCas9	positive selection	3336392
44264907	44264930	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	1.49026693009784	[47,60]	[0,0]	6	hSpCas9	positive selection	3336393
44309849	44309872	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	2.864559840463393	[21,19]	[0,0]	8	hSpCas9	positive selection	3336394
44275393	44275416	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.4499712893882311	[111,111]	[0,0]	2	hSpCas9	positive selection	3355648
44264899	44264922	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	6.257326211445835	[1,1]	[0,0]	9	hSpCas9	positive selection	3355649
44275388	44275411	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.9714924790500457	[299,299]	[0,0]	-6	hSpCas9	positive selection	3355650
44309683	44309706	11	+	26780180	HT29	viability (Avana library 4 designs)	CCTCGCTGCAAGTAAAGATGCGG	ALX4	ENSG00000052850	0.433642179762477	[]	[]	1	hSpCas9	negative selection	3406125
44275624	44275647	11	+	26780180	HT29	viability (Avana library 4 designs)	GGGTAACTCTGGCTCACCCAGGG	ALX4	ENSG00000052850	0.761713073858989	[]	[]	3	hSpCas9	negative selection	3406126
44310000	44310023	11	+	26780180	HT29	viability (Avana library 4 designs)	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.274513153036188	[]	[]	1	hSpCas9	negative selection	3406127
44309915	44309938	11	-	26780180	HT29	viability (Avana library 4 designs)	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	-0.0528224333465537	[]	[]	-1	hSpCas9	negative selection	3406128
44309683	44309706	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCGCTGCAAGTAAAGATGCGG	ALX4	ENSG00000052850	4.10002513767092	[]	[]	6	hSpCas9	negative selection	3478479
44275624	44275647	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGTAACTCTGGCTCACCCAGGG	ALX4	ENSG00000052850	2.75624126001559	[]	[]	4	hSpCas9	negative selection	3478480
44310000	44310023	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	2.66018605073399	[]	[]	4	hSpCas9	negative selection	3478481
44309915	44309938	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	-2.46558446471411	[]	[]	-3	hSpCas9	negative selection	3478482
44309683	44309706	11	+	26780180	A375	viability (Avana lentiGuide)	CCTCGCTGCAAGTAAAGATGCGG	ALX4	ENSG00000052850	0.569902289708837	[]	[]	0	hSpCas9	negative selection	3587138
44275624	44275647	11	+	26780180	A375	viability (Avana lentiGuide)	GGGTAACTCTGGCTCACCCAGGG	ALX4	ENSG00000052850	6.69390394324151	[]	[]	5	hSpCas9	negative selection	3587139
44310000	44310023	11	+	26780180	A375	viability (Avana lentiGuide)	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	1.30756604461434	[]	[]	1	hSpCas9	negative selection	3587140
44309915	44309938	11	-	26780180	A375	viability (Avana lentiGuide)	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	0.297473592804067	[]	[]	0	hSpCas9	negative selection	3587141
44309683	44309706	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCGCTGCAAGTAAAGATGCGG	ALX4	ENSG00000052850	-0.11654927062030901	[4]	[4,2]	-2	hSpCas9	positive selection	3695797
44275624	44275647	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGTAACTCTGGCTCACCCAGGG	ALX4	ENSG00000052850	0.17788747160629698	[4]	[4,5]	5	hSpCas9	positive selection	3695798
44310000	44310023	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.005578153598064899	[4]	[5,3]	0	hSpCas9	positive selection	3695799
44309915	44309938	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	0.2025863679618649	[5]	[5,6]	5	hSpCas9	positive selection	3695800
44309683	44309706	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCGCTGCAAGTAAAGATGCGG	ALX4	ENSG00000052850	0.2206866590815525	[5]	[6,4]	5	hSpCas9	positive selection	3804404
44275624	44275647	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGTAACTCTGGCTCACCCAGGG	ALX4	ENSG00000052850	-0.8714356968599949	[4]	[0,2]	-8	hSpCas9	positive selection	3804405
44310000	44310023	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.5485462023193463	[5]	[2,2]	-6	hSpCas9	positive selection	3804406
44309915	44309938	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCGGCACAACTTTCCTGTCGG	ALX4	ENSG00000052850	0.027547345977582183	[6]	[4,5]	0	hSpCas9	positive selection	3804407
44275393	44275416	11	-	26780180	A375	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	1.09487976754173	[]	[]	5	hSpCas9	negative selection	3912815
44264907	44264930	11	-	26780180	A375	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	0.615591984238733	[]	[]	2	hSpCas9	negative selection	3912816
44309849	44309872	11	-	26780180	A375	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	1.00968904231149	[]	[]	5	hSpCas9	negative selection	3912817
44310023	44310046	11	-	26780180	A375	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	1.08486177450517	[]	[]	5	hSpCas9	negative selection	3912818
44264899	44264922	11	+	26780180	A375	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.175486391513809	[]	[]	0	hSpCas9	negative selection	3912819
44275388	44275411	11	+	26780180	A375	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	1.33169898348421	[]	[]	7	hSpCas9	negative selection	3912820
44275393	44275416	11	-	26780180	HT29	viability (GeCKOv2 library)	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.82877425808574	[]	[]	3	hSpCas9	negative selection	4020781
44264907	44264930	11	-	26780180	HT29	viability (GeCKOv2 library)	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	0.920421904935533	[]	[]	4	hSpCas9	negative selection	4020782
44309849	44309872	11	-	26780180	HT29	viability (GeCKOv2 library)	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.54132955064719	[]	[]	1	hSpCas9	negative selection	4020783
44310023	44310046	11	-	26780180	HT29	viability (GeCKOv2 library)	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	1.10480093092995	[]	[]	5	hSpCas9	negative selection	4020784
44264899	44264922	11	+	26780180	HT29	viability (GeCKOv2 library)	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.210848354133777	[]	[]	0	hSpCas9	negative selection	4020785
44275388	44275411	11	+	26780180	HT29	viability (GeCKOv2 library)	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	1.06061190353529	[]	[]	5	hSpCas9	negative selection	4020786
44267578	44267601	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGCTCCCGCTTCCTCCACTTGG	ALX4	ENSG00000052850	0.12367804122073475	[3]	[2,2]	3	hSpCas9	positive selection	4138506
44275601	44275624	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCCCCACAGTGTCAGAGTCAGG	ALX4	ENSG00000052850	-0.010776031530742844	[3]	[0,3]	0	hSpCas9	positive selection	4138517
44267493	44267516	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGAGCTGAGAACTACGCCCAGG	ALX4	ENSG00000052850	0.033081557741036216	[3]	[1,2]	0	hSpCas9	positive selection	4138528
44275388	44275411	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.08977355383093716	[3]	[2,2]	2	hSpCas9	positive selection	4138540
44267578	44267601	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGCTCCCGCTTCCTCCACTTGG	ALX4	ENSG00000052850	0.9625480979847465	[4]	[2,0,2,4]	6	hSpCas9	positive selection	4202528
44275601	44275624	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCCCCACAGTGTCAGAGTCAGG	ALX4	ENSG00000052850	0.03476078785173203	[3]	[1,0,4,0]	0	hSpCas9	positive selection	4202539
44267493	44267516	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGAGCTGAGAACTACGCCCAGG	ALX4	ENSG00000052850	1.8107316726517528	[2]	[2,5,4,3]	9	hSpCas9	positive selection	4202550
44275388	44275411	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.385418604113649	[3]	[3,3,1,0]	3	hSpCas9	positive selection	4202562
44310023	44310046	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.2678327789600823	[3]	[2,1]	-5	hSpCas9	positive selection	4255442
44264907	44264930	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.04138872153727832	[2]	[2,1]	-1	hSpCas9	positive selection	4255443
44309849	44309872	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.162387018415863	[1]	[2,1]	3	hSpCas9	positive selection	4255444
44275393	44275416	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.35247174014402244	[2]	[2,2]	7	hSpCas9	positive selection	4319724
44264899	44264922	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.08575919653961073	[0]	[0,0]	1	hSpCas9	positive selection	4319725
44275388	44275411	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.03462657433611843	[3]	[3,2]	0	hSpCas9	positive selection	4319726
44275644	44275666	11	+	27760321	OCIAML3	viability	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.4531767214453346	[771,589]	[578,911]	5	hSpCas9	negative selection	4377587
44309585	44309607	11	+	27760321	OCIAML3	viability	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.18285792211138108	[729,609]	[561,631]	2	hSpCas9	negative selection	4377588
44309683	44309705	11	-	27760321	OCIAML3	viability	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	-0.2528100813247599	[783,711]	[372,643]	-3	hSpCas9	negative selection	4377589
44309851	44309873	11	+	27760321	OCIAML3	viability	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.16516771829672816	[954,811]	[667,907]	2	hSpCas9	negative selection	4377590
44309930	44309952	11	+	27760321	OCIAML3	viability	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.4593203796560066	[1284,1039]	[1027,1523]	5	hSpCas9	negative selection	4377591
44275644	44275666	11	+	27760321	OCIAML2	viability	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.22326147586769363	[771,589]	[509,806]	3	hSpCas9	negative selection	4461050
44309585	44309607	11	+	27760321	OCIAML2	viability	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	-0.21452698925331465	[729,609]	[412,533]	-3	hSpCas9	negative selection	4461051
44309683	44309705	11	-	27760321	OCIAML2	viability	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.26423447283660373	[783,711]	[648,827]	3	hSpCas9	negative selection	4461052
44309851	44309873	11	+	27760321	OCIAML2	viability	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.3601445037193314	[954,811]	[849,998]	5	hSpCas9	negative selection	4461053
44309930	44309952	11	+	27760321	OCIAML2	viability	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.24119629493762273	[1284,1039]	[957,1299]	3	hSpCas9	negative selection	4461054
44275644	44275666	11	+	27760321	MV411	viability	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	-0.04578173932197993	[771,589]	[443,413]	0	hSpCas9	negative selection	4544513
44309585	44309607	11	+	27760321	MV411	viability	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.5663826649745811	[729,609]	[713,558]	4	hSpCas9	negative selection	4544514
44309683	44309705	11	-	27760321	MV411	viability	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.5580332956654575	[783,711]	[764,667]	4	hSpCas9	negative selection	4544515
44309851	44309873	11	+	27760321	MV411	viability	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.061717721505220036	[954,811]	[438,857]	0	hSpCas9	negative selection	4544516
44309930	44309952	11	+	27760321	MV411	viability	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.9686807429856004	[1284,1039]	[1812,1012]	7	hSpCas9	negative selection	4544517
44275644	44275666	11	+	27760321	HL60	viability	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.11292348520962325	[771,589]	[661,527]	1	hSpCas9	negative selection	4627976
44309585	44309607	11	+	27760321	HL60	viability	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.233540346039408	[729,609]	[453,838]	3	hSpCas9	negative selection	4627977
44309683	44309705	11	-	27760321	HL60	viability	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.05387233000205849	[783,711]	[661,603]	0	hSpCas9	negative selection	4627978
44309851	44309873	11	+	27760321	HL60	viability	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.16671172146885316	[954,811]	[687,933]	2	hSpCas9	negative selection	4627979
44309930	44309952	11	+	27760321	HL60	viability	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	-0.279980845743498	[1284,1039]	[890,657]	-3	hSpCas9	negative selection	4627980
44275644	44275666	11	+	27760321	HT1080	viability	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	-0.21848161979794523	[589,460]	[146,215]	-1	hSpCas9	negative selection	4711439
44309585	44309607	11	+	27760321	HT1080	viability	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.7912352351507594	[609,475]	[370,377]	4	hSpCas9	negative selection	4711440
44309683	44309705	11	-	27760321	HT1080	viability	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.39442223597711745	[711,555]	[257,412]	2	hSpCas9	negative selection	4711441
44309851	44309873	11	+	27760321	HT1080	viability	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.9615162033563702	[811,633]	[231,920]	5	hSpCas9	negative selection	4711442
44309930	44309952	11	+	27760321	HT1080	viability	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	2.1457578840583045	[1039,811]	[1652,1609]	9	hSpCas9	negative selection	4711443
44275644	44275666	11	+	27760321	HT29	viability after 7 days	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.47714184883954847	[589,460]	[961,909,950]	7	hSpCas9	negative selection	4794902
44309585	44309607	11	+	27760321	HT29	viability after 7 days	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.04473152232256972	[609,475]	[915,606,665]	0	hSpCas9	negative selection	4794903
44309683	44309705	11	-	27760321	HT29	viability after 7 days	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.30099624300105	[711,555]	[1114,615,1286]	4	hSpCas9	negative selection	4794904
44309851	44309873	11	+	27760321	HT29	viability after 7 days	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.2500606527099072	[811,633]	[1261,1214,867]	4	hSpCas9	negative selection	4794905
44309930	44309952	11	+	27760321	HT29	viability after 7 days	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.3302265919440177	[1039,811]	[1646,1405,1457]	5	hSpCas9	negative selection	4794906
44275644	44275666	11	+	27760321	HT29	viability after 25 days	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.9156503771430615	[589,460]	[1005,1224,1178]	9	hSpCas9	negative selection	4878365
44309585	44309607	11	+	27760321	HT29	viability after 25 days	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.42446547241514243	[609,475]	[665,609,1277]	4	hSpCas9	negative selection	4878366
44309683	44309705	11	-	27760321	HT29	viability after 25 days	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.4739601741704953	[711,555]	[982,857,1197]	5	hSpCas9	negative selection	4878367
44309851	44309873	11	+	27760321	HT29	viability after 25 days	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	1.0670510846173493	[811,633]	[1573,1583,2078]	9	hSpCas9	negative selection	4878368
44309930	44309952	11	+	27760321	HT29	viability after 25 days	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.5820227274017906	[1039,811]	[1547,1649,1550]	6	hSpCas9	negative selection	4878369
44275644	44275666	11	+	27760321	HT29	viability after 22 days	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.5187927183568302	[589,460]	[931,984,690]	6	hSpCas9	negative selection	4961828
44309585	44309607	11	+	27760321	HT29	viability after 22 days	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.6262836853202052	[609,475]	[731,1025,1156]	7	hSpCas9	negative selection	4961829
44309683	44309705	11	-	27760321	HT29	viability after 22 days	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.12966903421587117	[711,555]	[615,643,1153]	1	hSpCas9	negative selection	4961830
44309851	44309873	11	+	27760321	HT29	viability after 22 days	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.9368765328823518	[811,633]	[1741,1503,1549]	9	hSpCas9	negative selection	4961831
44309930	44309952	11	+	27760321	HT29	viability after 22 days	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.4246953561711311	[1039,811]	[1588,1458,1256]	4	hSpCas9	negative selection	4961832
44275644	44275666	11	+	27760321	HT29	viability after 19 days	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.6271551143431471	[589,460]	[1035,680,1072]	6	hSpCas9	negative selection	5045291
44309585	44309607	11	+	27760321	HT29	viability after 19 days	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.6427922559586385	[609,475]	[1275,821,846]	6	hSpCas9	negative selection	5045292
44309683	44309705	11	-	27760321	HT29	viability after 19 days	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.18527955164291887	[711,555]	[935,842,709]	1	hSpCas9	negative selection	5045293
44309851	44309873	11	+	27760321	HT29	viability after 19 days	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.667147139823359	[811,633]	[1595,1275,1103]	6	hSpCas9	negative selection	5045294
44309930	44309952	11	+	27760321	HT29	viability after 19 days	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.34965465441667765	[1039,811]	[1377,1707,978]	3	hSpCas9	negative selection	5045295
44275644	44275666	11	+	27760321	HT29	viability after 16 days	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.9607906549380998	[589,460]	[1156,1115,1161]	9	hSpCas9	negative selection	5128754
44309585	44309607	11	+	27760321	HT29	viability after 16 days	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.5331944402215407	[609,475]	[1132,773,756]	6	hSpCas9	negative selection	5128755
44309683	44309705	11	-	27760321	HT29	viability after 16 days	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.386895255939967	[711,555]	[720,885,1156]	4	hSpCas9	negative selection	5128756
44309851	44309873	11	+	27760321	HT29	viability after 16 days	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.7529432956280651	[811,633]	[1261,1318,1499]	8	hSpCas9	negative selection	5128757
44309930	44309952	11	+	27760321	HT29	viability after 16 days	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.6806391552715245	[1039,811]	[1873,1726,1398]	7	hSpCas9	negative selection	5128758
44275644	44275666	11	+	27760321	HT29	viability after 13 days	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.3953077281278161	[589,460]	[532,1069,802]	5	hSpCas9	negative selection	5212217
44309585	44309607	11	+	27760321	HT29	viability after 13 days	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.23644533577168736	[609,475]	[796,770,662]	3	hSpCas9	negative selection	5212218
44309683	44309705	11	-	27760321	HT29	viability after 13 days	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.2897703186484035	[711,555]	[707,975,1006]	3	hSpCas9	negative selection	5212219
44309851	44309873	11	+	27760321	HT29	viability after 13 days	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.7308880794938117	[811,633]	[1314,1431,1426]	8	hSpCas9	negative selection	5212220
44309930	44309952	11	+	27760321	HT29	viability after 13 days	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.570201230296667	[1039,811]	[1652,1559,1572]	7	hSpCas9	negative selection	5212221
44275644	44275666	11	+	27760321	HT29	viability after 10 days	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.49875619209822	[589,460]	[975,838,962]	6	hSpCas9	negative selection	5295680
44309585	44309607	11	+	27760321	HT29	viability after 10 days	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	0.28835523259779716	[609,475]	[922,830,731]	4	hSpCas9	negative selection	5295681
44309683	44309705	11	-	27760321	HT29	viability after 10 days	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	-0.025022771229467833	[711,555]	[1066,510,748]	0	hSpCas9	negative selection	5295682
44309851	44309873	11	+	27760321	HT29	viability after 10 days	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.5356519000777231	[811,633]	[1389,1300,1235]	7	hSpCas9	negative selection	5295683
44309930	44309952	11	+	27760321	HT29	viability after 10 days	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.5672308307426097	[1039,811]	[1862,1324,1934]	7	hSpCas9	negative selection	5295684
44275644	44275666	11	+	27760321	MOLM13	viability	GGGAGCTCTCTTTAGCTGAGGG	ALX4	ENSG00000052850	0.12772176919864053	[771,589]	[361,462]	0	hSpCas9	negative selection	5379143
44309585	44309607	11	+	27760321	MOLM13	viability	ACGTGCACTCACCGTAGCAGGG	ALX4	ENSG00000052850	1.0247414243136694	[729,609]	[799,736]	7	hSpCas9	negative selection	5379144
44309683	44309705	11	-	27760321	MOLM13	viability	CGCATCTTTACTTGCAGCGAGG	ALX4	ENSG00000052850	0.09771137931993823	[783,711]	[823,133]	0	hSpCas9	negative selection	5379145
44309851	44309873	11	+	27760321	MOLM13	viability	TGCTGCCCAGCGCCGTAACGGG	ALX4	ENSG00000052850	0.8283714354520162	[954,811]	[1007,774]	6	hSpCas9	negative selection	5379146
44309930	44309952	11	+	27760321	MOLM13	viability	TGCCGAACTTGTCGCCTCCGGG	ALX4	ENSG00000052850	0.33781273450658555	[1284,1039]	[575,1035]	2	hSpCas9	negative selection	5379147
44309606	44309629	11	+	27661255	K562	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	-0.11371290588130917	[649,562]	[483,418]	-4	dCas9-KRAB	negative selection	5461944
44310000	44310023	11	+	27661255	K562	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.1219182106252753	[1403,1580]	[1428,1179]	4	dCas9-KRAB	negative selection	5461945
44309659	44309682	11	-	27661255	K562	viability	GCCTGCAAGACGCCCCCGGACGG	ALX4	ENSG00000052850	0.6339932562339796	[107,144]	[216,103]	9	dCas9-KRAB	negative selection	5461946
44309863	44309886	11	-	27661255	K562	viability	GCCAAGAGCCGGGCCCGTTACGG	ALX4	ENSG00000052850	0.21210549651847566	[289,340]	[316,268]	7	dCas9-KRAB	negative selection	5461947
44310023	44310046	11	-	27260156	BXPC3	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.014422957476057152	[715]	[672,725,755,891]	0	hSpCas9	negative selection	5527902
44264907	44264930	11	-	27260156	BXPC3	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.4065200778799555	[292]	[202,207,296,218]	-7	hSpCas9	negative selection	5527903
44309849	44309872	11	-	27260156	BXPC3	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.011754218619232315	[183]	[189,182,165,241]	0	hSpCas9	negative selection	5527904
44275393	44275416	11	-	27260156	BXPC3	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.1829964837397421	[264]	[225,221,208,330]	-4	hSpCas9	negative selection	5592184
44264899	44264922	11	+	27260156	BXPC3	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	1.263719245215344	[11]	[38,18,31,29]	9	hSpCas9	negative selection	5592185
44275388	44275411	11	+	27260156	BXPC3	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.13420694356922613	[802]	[636,707,863,878]	-3	hSpCas9	negative selection	5592186
44310023	44310046	11	-	27260156	A673	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.3036479601116313	[715]	[743,635,695,716]	-6	hSpCas9	negative selection	5649153
44264907	44264930	11	-	27260156	A673	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.7203079213980347	[292]	[282,177,186,214]	-9	hSpCas9	negative selection	5649154
44309849	44309872	11	-	27260156	A673	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.002195068690107993	[183]	[192,220,291,171]	0	hSpCas9	negative selection	5649155
44275393	44275416	11	-	27260156	A673	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.2552095686082517	[264]	[319,214,232,307]	-6	hSpCas9	negative selection	5713435
44264899	44264922	11	+	27260156	A673	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.0169385281477874	[11]	[27,8,8,13]	0	hSpCas9	negative selection	5713436
44275388	44275411	11	+	27260156	A673	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.28262776674419454	[802]	[952,764,813,647]	-6	hSpCas9	negative selection	5713437
44310023	44310046	11	-	27260156	A375	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.22666349605052238	[715]	[1085,984,981,871]	3	hSpCas9	negative selection	5770404
44264907	44264930	11	-	27260156	A375	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.17167167809969663	[292]	[269,329,428,200]	-2	hSpCas9	negative selection	5770405
44309849	44309872	11	-	27260156	A375	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.5447849440578987	[183]	[273,399,391,210]	7	hSpCas9	negative selection	5770406
44275393	44275416	11	-	27260156	A375	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.33575186199475693	[264]	[270,367,294,82]	-5	hSpCas9	negative selection	5834686
44264899	44264922	11	+	27260156	A375	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-1.662891668545556	[11]	[1,10,4,0]	-9	hSpCas9	negative selection	5834687
44275388	44275411	11	+	27260156	A375	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.1709077307262563	[802]	[801,621,971,895]	-2	hSpCas9	negative selection	5834688
44310023	44310046	11	-	27260156	COLO741	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.06369769839142558	[715]	[1042,1104,741]	1	hSpCas9	negative selection	5891655
44264907	44264930	11	-	27260156	COLO741	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.24937003024994497	[292]	[332,316,296]	-5	hSpCas9	negative selection	5891656
44309849	44309872	11	-	27260156	COLO741	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.12307348628660941	[183]	[297,216,255]	2	hSpCas9	negative selection	5891657
44275393	44275416	11	-	27260156	COLO741	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.09254829702775802	[264]	[407,328,349]	2	hSpCas9	negative selection	5955937
44264899	44264922	11	+	27260156	COLO741	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-1.2162910164840062	[11]	[3,14,0]	-9	hSpCas9	negative selection	5955938
44275388	44275411	11	+	27260156	COLO741	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.07420158188471904	[802]	[1088,853,986]	-2	hSpCas9	negative selection	5955939
44310023	44310046	11	-	27260156	CAL120	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.33423470632357943	[715]	[1627,1013,808]	5	hSpCas9	negative selection	6012906
44264907	44264930	11	-	27260156	CAL120	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	0.14749429849978435	[292]	[294,718,184]	2	hSpCas9	negative selection	6012907
44309849	44309872	11	-	27260156	CAL120	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	-0.2880463996351774	[183]	[259,214,99]	-4	hSpCas9	negative selection	6012908
44275393	44275416	11	-	27260156	CAL120	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.3586922828607154	[264]	[150,266,335]	-5	hSpCas9	negative selection	6077188
44264899	44264922	11	+	27260156	CAL120	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.003363866164307616	[11]	[1,39,0]	0	hSpCas9	negative selection	6077189
44275388	44275411	11	+	27260156	CAL120	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.05825455077402475	[802]	[1444,618,888]	-1	hSpCas9	negative selection	6077190
44310023	44310046	11	-	27260156	CADOES1	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.08394561277067303	[715]	[583,648,505,779]	-1	hSpCas9	negative selection	6134157
44264907	44264930	11	-	27260156	CADOES1	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.27217715405593956	[292]	[252,225,262,157]	-5	hSpCas9	negative selection	6134158
44309849	44309872	11	-	27260156	CADOES1	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.1604960640155626	[183]	[230,138,199,194]	2	hSpCas9	negative selection	6134159
44275393	44275416	11	-	27260156	CADOES1	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.4437661538288892	[264]	[276,163,141,139]	-7	hSpCas9	negative selection	6198439
44264899	44264922	11	+	27260156	CADOES1	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.9740967886898941	[11]	[1,0,6,12]	-9	hSpCas9	negative selection	6198440
44275388	44275411	11	+	27260156	CADOES1	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.016363602433509095	[802]	[804,533,748,869]	0	hSpCas9	negative selection	6198441
44310023	44310046	11	-	27260156	EWS502	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.11766947650403164	[715]	[605,639,689,883]	-2	hSpCas9	negative selection	6255408
44264907	44264930	11	-	27260156	EWS502	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.2939908717970935	[292]	[237,247,384,135]	-5	hSpCas9	negative selection	6255409
44309849	44309872	11	-	27260156	EWS502	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.9049515352456688	[183]	[330,316,493,320]	9	hSpCas9	negative selection	6255410
44275393	44275416	11	-	27260156	EWS502	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.06493263837955843	[264]	[229,421,210,312]	1	hSpCas9	negative selection	6319690
44264899	44264922	11	+	27260156	EWS502	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.04428288702630123	[11]	[4,8,21,17]	0	hSpCas9	negative selection	6319691
44275388	44275411	11	+	27260156	EWS502	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.30410888169249944	[802]	[575,657,701,842]	-5	hSpCas9	negative selection	6319692
44310023	44310046	11	-	27260156	EW8	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.07412003407735401	[715]	[502,644,493,565]	-1	hSpCas9	negative selection	6376659
44264907	44264930	11	-	27260156	EW8	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.18778613597047233	[292]	[304,218,131,200]	-4	hSpCas9	negative selection	6376660
44309849	44309872	11	-	27260156	EW8	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.19640345107275237	[183]	[183,181,191,122]	3	hSpCas9	negative selection	6376661
44275393	44275416	11	-	27260156	EW8	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.13520976709009025	[264]	[320,169,174,295]	2	hSpCas9	negative selection	6440941
44264899	44264922	11	+	27260156	EW8	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.3575405221655048	[11]	[13,26,0,9]	6	hSpCas9	negative selection	6440942
44275388	44275411	11	+	27260156	EW8	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.2432758094237868	[802]	[566,537,527,569]	-4	hSpCas9	negative selection	6440943
44310023	44310046	11	-	27260156	CORL105	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.10584920497113559	[715]	[686,950,1234,778]	2	hSpCas9	negative selection	6497910
44264907	44264930	11	-	27260156	CORL105	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.6255800491818148	[292]	[263,222,210,190]	-8	hSpCas9	negative selection	6497911
44309849	44309872	11	-	27260156	CORL105	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.40257277913746226	[183]	[351,260,285,242]	7	hSpCas9	negative selection	6497912
44275393	44275416	11	-	27260156	CORL105	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.015517579758096756	[264]	[359,308,315,245]	0	hSpCas9	negative selection	6562192
44264899	44264922	11	+	27260156	CORL105	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-1.0553960525597086	[11]	[4,1,18,2]	-9	hSpCas9	negative selection	6562193
44275388	44275411	11	+	27260156	CORL105	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.38302944166422	[802]	[623,606,781,877]	-6	hSpCas9	negative selection	6562194
44310023	44310046	11	-	27260156	HS294T	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.3363781545735488	[715]	[303,324,469,293]	4	hSpCas9	negative selection	6619161
44264907	44264930	11	-	27260156	HS294T	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.5215441283345769	[292]	[59,81,91,83]	-6	hSpCas9	negative selection	6619162
44309849	44309872	11	-	27260156	HS294T	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.5198739002964698	[183]	[68,137,108,91]	7	hSpCas9	negative selection	6619163
44275393	44275416	11	-	27260156	HS294T	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.2818279902595745	[264]	[81,74,82,99]	-4	hSpCas9	negative selection	6683443
44264899	44264922	11	+	27260156	HS294T	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.7371581605948139	[11]	[2,1,3,1]	-8	hSpCas9	negative selection	6683444
44275388	44275411	11	+	27260156	HS294T	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.0620534634377885	[802]	[369,267,224,323]	-1	hSpCas9	negative selection	6683445
44310023	44310046	11	-	27260156	HCC44	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.23342588611756898	[715]	[1013,790,1142,914]	4	hSpCas9	negative selection	6740412
44264907	44264930	11	-	27260156	HCC44	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	0.18727320909810174	[292]	[418,280,359,457]	3	hSpCas9	negative selection	6740413
44309849	44309872	11	-	27260156	HCC44	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.5506072841435065	[183]	[465,238,408,149]	8	hSpCas9	negative selection	6740414
44275393	44275416	11	-	27260156	HCC44	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.21984089081543912	[264]	[332,137,311,276]	-4	hSpCas9	negative selection	6804694
44264899	44264922	11	+	27260156	HCC44	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-2.500401559212328	[11]	[6,0,0,0]	-9	hSpCas9	negative selection	6804695
44275388	44275411	11	+	27260156	HCC44	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.11169509765173369	[802]	[928,946,1233,854]	1	hSpCas9	negative selection	6804696
44310023	44310046	11	-	27260156	G402	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.13697601455476616	[715]	[1081,905,918,946]	1	hSpCas9	negative selection	6861663
44264907	44264930	11	-	27260156	G402	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.07604676652538012	[292]	[343,256,320,424]	-1	hSpCas9	negative selection	6861664
44309849	44309872	11	-	27260156	G402	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	-0.023179426411247483	[183]	[216,367,129,177]	0	hSpCas9	negative selection	6861665
44275393	44275416	11	-	27260156	G402	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.059115278211639755	[264]	[335,594,219,118]	0	hSpCas9	negative selection	6925945
44264899	44264922	11	+	27260156	G402	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	1.6744527554758024	[11]	[0,0,117,56]	9	hSpCas9	negative selection	6925946
44275388	44275411	11	+	27260156	G402	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.27439735642415786	[802]	[718,1612,936,1412]	3	hSpCas9	negative selection	6925947
44310023	44310046	11	-	27260156	L33	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.16492902834049827	[715]	[798,379,455,758]	3	hSpCas9	negative selection	6982914
44264907	44264930	11	-	27260156	L33	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.21081005392940178	[292]	[253,130,159,184]	-5	hSpCas9	negative selection	6982915
44309849	44309872	11	-	27260156	L33	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.11591854134012602	[183]	[173,87,123,211]	2	hSpCas9	negative selection	6982916
44275393	44275416	11	-	27260156	L33	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.012383680223969407	[264]	[267,109,148,276]	0	hSpCas9	negative selection	7047196
44264899	44264922	11	+	27260156	L33	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-1.2238877661520533	[11]	[0,6,0,0]	-9	hSpCas9	negative selection	7047197
44275388	44275411	11	+	27260156	L33	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.04739828028638571	[802]	[829,308,553,642]	-1	hSpCas9	negative selection	7047198
44310023	44310046	11	-	27260156	K562	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.29120067169095176	[715]	[787,622,1132,578]	3	hSpCas9	negative selection	7104165
44264907	44264930	11	-	27260156	K562	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	0.7779259280824489	[292]	[440,79,305,882]	8	hSpCas9	negative selection	7104166
44309849	44309872	11	-	27260156	K562	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.6825868447230384	[183]	[360,122,103,438]	8	hSpCas9	negative selection	7104167
44275393	44275416	11	-	27260156	K562	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.26472032420447145	[264]	[249,319,216,334]	3	hSpCas9	negative selection	7168447
44264899	44264922	11	+	27260156	K562	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	1.970599749218255	[11]	[0,105,0,56]	9	hSpCas9	negative selection	7168448
44275388	44275411	11	+	27260156	K562	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.10171197106902519	[802]	[884,745,656,774]	1	hSpCas9	negative selection	7168449
44310023	44310046	11	-	27260156	HT29	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.07668557804739884	[715]	[1001,879,771,677]	-2	hSpCas9	negative selection	7225416
44264907	44264930	11	-	27260156	HT29	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.035452796724411484	[292]	[291,475,239,381]	0	hSpCas9	negative selection	7225417
44309849	44309872	11	-	27260156	HT29	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.2099631898135912	[183]	[429,147,292,175]	4	hSpCas9	negative selection	7225418
44275393	44275416	11	-	27260156	HT29	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.286388710488524	[264]	[393,263,208,204]	-5	hSpCas9	negative selection	7289698
44264899	44264922	11	+	27260156	HT29	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.04383998960180602	[11]	[12,11,13,19]	0	hSpCas9	negative selection	7289699
44275388	44275411	11	+	27260156	HT29	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.09433836956808006	[802]	[1162,1323,940,796]	1	hSpCas9	negative selection	7289700
44310023	44310046	11	-	27260156	MHHES1	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.04983633706469326	[715]	[921,794,782,647]	-1	hSpCas9	negative selection	7346667
44264907	44264930	11	-	27260156	MHHES1	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.009416968881737708	[292]	[291,228,556,234]	0	hSpCas9	negative selection	7346668
44309849	44309872	11	-	27260156	MHHES1	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.12770952321554563	[183]	[502,123,142,166]	2	hSpCas9	negative selection	7346669
44275393	44275416	11	-	27260156	MHHES1	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.41567042761121187	[264]	[150,243,252,232]	-7	hSpCas9	negative selection	7410949
44264899	44264922	11	+	27260156	MHHES1	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.47594598058892945	[11]	[34,4,0,1]	-7	hSpCas9	negative selection	7410950
44275388	44275411	11	+	27260156	MHHES1	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.006510422099267554	[802]	[1079,1258,611,752]	0	hSpCas9	negative selection	7410951
44310023	44310046	11	-	27260156	MEWO	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.09266124916987828	[715]	[720,507,673]	-2	hSpCas9	negative selection	7467918
44264907	44264930	11	-	27260156	MEWO	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.061989677499399876	[292]	[259,305,220]	-1	hSpCas9	negative selection	7467919
44309849	44309872	11	-	27260156	MEWO	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.09024195998613349	[183]	[244,118,197]	2	hSpCas9	negative selection	7467920
44275393	44275416	11	-	27260156	MEWO	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.07450176420682997	[264]	[371,183,248]	1	hSpCas9	negative selection	7532200
44264899	44264922	11	+	27260156	MEWO	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.07334586086249129	[11]	[19,15,0]	1	hSpCas9	negative selection	7532201
44275388	44275411	11	+	27260156	MEWO	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.0009227892762628809	[802]	[811,693,760]	0	hSpCas9	negative selection	7532202
44310023	44310046	11	-	27260156	LNCAPCLONEFGC	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.07616855426806324	[715]	[540,708,636,571]	-1	hSpCas9	negative selection	7589169
44264907	44264930	11	-	27260156	LNCAPCLONEFGC	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.16740976964018517	[292]	[213,230,249,252]	-3	hSpCas9	negative selection	7589170
44309849	44309872	11	-	27260156	LNCAPCLONEFGC	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.7987995969308369	[183]	[186,356,301,312]	9	hSpCas9	negative selection	7589171
44275393	44275416	11	-	27260156	LNCAPCLONEFGC	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.16136420187788025	[264]	[205,189,449,260]	2	hSpCas9	negative selection	7653451
44264899	44264922	11	+	27260156	LNCAPCLONEFGC	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.7828929235659583	[11]	[8,26,8,27]	9	hSpCas9	negative selection	7653452
44275388	44275411	11	+	27260156	LNCAPCLONEFGC	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.17930718116471522	[802]	[641,573,664,695]	-3	hSpCas9	negative selection	7653453
44310023	44310046	11	-	27260156	PANC0327	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.037321277068265934	[715]	[1046,308,536,793]	0	hSpCas9	negative selection	7710420
44264907	44264930	11	-	27260156	PANC0327	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.11572727180213849	[292]	[363,125,384,110]	-2	hSpCas9	negative selection	7710421
44309849	44309872	11	-	27260156	PANC0327	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.38960776920868445	[183]	[187,147,315,210]	6	hSpCas9	negative selection	7710422
44275393	44275416	11	-	27260156	PANC0327	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.12255350098557816	[264]	[317,160,112,449]	1	hSpCas9	negative selection	7774702
44264899	44264922	11	+	27260156	PANC0327	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.7701383912927682	[11]	[1,18,0,0]	-8	hSpCas9	negative selection	7774703
44275388	44275411	11	+	27260156	PANC0327	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.2519296101825065	[802]	[1029,931,974,464]	4	hSpCas9	negative selection	7774704
44310023	44310046	11	-	27260156	NCIH2009	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.19244647943821092	[715]	[1138,1285,998]	2	hSpCas9	negative selection	7831671
44264907	44264930	11	-	27260156	NCIH2009	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	0.48408647463596	[292]	[524,702,476]	6	hSpCas9	negative selection	7831672
44309849	44309872	11	-	27260156	NCIH2009	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.4153972984669605	[183]	[414,245,382]	6	hSpCas9	negative selection	7831673
44275393	44275416	11	-	27260156	NCIH2009	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.37942403127354674	[264]	[518,213,167]	-5	hSpCas9	negative selection	7895953
44264899	44264922	11	+	27260156	NCIH2009	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.30285243383740834	[11]	[26,34,0]	4	hSpCas9	negative selection	7895954
44275388	44275411	11	+	27260156	NCIH2009	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.13882608091398863	[802]	[1028,1030,996]	-2	hSpCas9	negative selection	7895955
44310023	44310046	11	-	27260156	NCIH1373	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	1.1530252550887043	[715]	[1309,1679,2490,408]	9	hSpCas9	negative selection	7952922
44264907	44264930	11	-	27260156	NCIH1373	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.29792896698651483	[292]	[445,159,234,69]	-3	hSpCas9	negative selection	7952923
44309849	44309872	11	-	27260156	NCIH1373	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.21243059598440994	[183]	[89,232,362,63]	2	hSpCas9	negative selection	7952924
44275393	44275416	11	-	27260156	NCIH1373	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.4611781276021715	[264]	[377,67,239,56]	-4	hSpCas9	negative selection	8017204
44264899	44264922	11	+	27260156	NCIH1373	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.3157366608942871	[11]	[2,0,56,0]	3	hSpCas9	negative selection	8017205
44275388	44275411	11	+	27260156	NCIH1373	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.006632418860447298	[802]	[667,540,839,413]	0	hSpCas9	negative selection	8017206
44310023	44310046	11	-	27260156	PATU8902	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.08125551706850054	[715]	[687,1066,1179,1274]	0	hSpCas9	negative selection	8074173
44264907	44264930	11	-	27260156	PATU8902	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.6207359874500477	[292]	[198,323,293,231]	-5	hSpCas9	negative selection	8074174
44309849	44309872	11	-	27260156	PATU8902	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	1.1544792793244016	[183]	[642,853,224,654]	9	hSpCas9	negative selection	8074175
44275393	44275416	11	-	27260156	PATU8902	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-1.1588656922427716	[264]	[174,51,225,193]	-8	hSpCas9	negative selection	8138455
44264899	44264922	11	+	27260156	PATU8902	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-2.5346188173770994	[11]	[0,1,4,2]	-9	hSpCas9	negative selection	8138456
44275388	44275411	11	+	27260156	PATU8902	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.09290431807725508	[802]	[1102,1255,1199,1202]	0	hSpCas9	negative selection	8138457
44310023	44310046	11	-	27260156	PANC1	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.2398422907442428	[715]	[656,722,774,736]	4	hSpCas9	negative selection	8195424
44264907	44264930	11	-	27260156	PANC1	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.025977663039801868	[292]	[324,109,339,189]	0	hSpCas9	negative selection	8195425
44309849	44309872	11	-	27260156	PANC1	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.2831550786520243	[183]	[195,344,120,142]	4	hSpCas9	negative selection	8195426
44275393	44275416	11	-	27260156	PANC1	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.04647422548160851	[264]	[320,203,188,166]	0	hSpCas9	negative selection	8259706
44264899	44264922	11	+	27260156	PANC1	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	1.7160315902568941	[11]	[24,22,4,72]	9	hSpCas9	negative selection	8259707
44275388	44275411	11	+	27260156	PANC1	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.2464063109388258	[802]	[596,1089,876,764]	4	hSpCas9	negative selection	8259708
44310023	44310046	11	-	27260156	PANC0813	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.2393908884199648	[715]	[1088,1120,1057,725]	4	hSpCas9	negative selection	8316675
44264907	44264930	11	-	27260156	PANC0813	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.22054031367717386	[292]	[205,285,364,314]	-4	hSpCas9	negative selection	8316676
44309849	44309872	11	-	27260156	PANC0813	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.004019334162073118	[183]	[264,179,242,184]	0	hSpCas9	negative selection	8316677
44275393	44275416	11	-	27260156	PANC0813	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.11172703728526312	[264]	[363,288,276,231]	-2	hSpCas9	negative selection	8380957
44264899	44264922	11	+	27260156	PANC0813	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.7381463338364531	[11]	[14,0,2,14]	-8	hSpCas9	negative selection	8380958
44275388	44275411	11	+	27260156	PANC0813	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.0984399964391357	[802]	[737,919,750,1087]	-2	hSpCas9	negative selection	8380959
44310023	44310046	11	-	27260156	RDES	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.022334027923198163	[715]	[712,774,836,1060]	0	hSpCas9	negative selection	8437926
44264907	44264930	11	-	27260156	RDES	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.17514616800857807	[292]	[290,274,275,352]	-3	hSpCas9	negative selection	8437927
44309849	44309872	11	-	27260156	RDES	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.43905381680389577	[183]	[246,277,255,379]	7	hSpCas9	negative selection	8437928
44275393	44275416	11	-	27260156	RDES	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.0008982042563666637	[264]	[186,353,297,406]	0	hSpCas9	negative selection	8502208
44264899	44264922	11	+	27260156	RDES	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.5088707852033458	[11]	[15,14,32,14]	7	hSpCas9	negative selection	8502209
44275388	44275411	11	+	27260156	RDES	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.1355509498098474	[802]	[707,655,893,1179]	-2	hSpCas9	negative selection	8502210
44310023	44310046	11	-	27260156	PC3	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.01500826923313725	[715]	[529,510,1012,907]	0	hSpCas9	negative selection	8559177
44264907	44264930	11	-	27260156	PC3	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.1863579929878867	[292]	[179,295,436,183]	-4	hSpCas9	negative selection	8559178
44309849	44309872	11	-	27260156	PC3	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.3715627357692206	[183]	[179,335,265,165]	7	hSpCas9	negative selection	8559179
44275393	44275416	11	-	27260156	PC3	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.11826628382371174	[264]	[145,207,379,317]	-3	hSpCas9	negative selection	8623459
44264899	44264922	11	+	27260156	PC3	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.5778397508945634	[11]	[13,11,45,9]	9	hSpCas9	negative selection	8623460
44275388	44275411	11	+	27260156	PC3	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.3209225080945447	[802]	[413,708,831,715]	-6	hSpCas9	negative selection	8623461
44310023	44310046	11	-	27260156	PATU8988T	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.20969383099311878	[715]	[769,1125,522,816]	3	hSpCas9	negative selection	8680428
44264907	44264930	11	-	27260156	PATU8988T	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-1.2477491173150588	[292]	[129,123,89,134]	-9	hSpCas9	negative selection	8680429
44309849	44309872	11	-	27260156	PATU8988T	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.4630018220793216	[183]	[326,271,171,209]	7	hSpCas9	negative selection	8680430
44275393	44275416	11	-	27260156	PATU8988T	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.1312753311503847	[264]	[258,409,236,223]	2	hSpCas9	negative selection	8744710
44264899	44264922	11	+	27260156	PATU8988T	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.45290027857246695	[11]	[0,15,4,12]	-6	hSpCas9	negative selection	8744711
44275388	44275411	11	+	27260156	PATU8988T	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.32720440040681853	[802]	[1136,995,990,753]	5	hSpCas9	negative selection	8744712
44310023	44310046	11	-	27260156	T47D	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.010346201115041254	[715]	[989,834,729,806]	0	hSpCas9	negative selection	8801679
44264907	44264930	11	-	27260156	T47D	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.24966093228663278	[292]	[255,187,375,336]	-5	hSpCas9	negative selection	8801680
44309849	44309872	11	-	27260156	T47D	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.23903587316849073	[183]	[298,215,274,223]	5	hSpCas9	negative selection	8801681
44275393	44275416	11	-	27260156	T47D	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.17485938101323673	[264]	[274,254,294,269]	-4	hSpCas9	negative selection	8865961
44264899	44264922	11	+	27260156	T47D	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.18653767510245167	[11]	[3,12,17,13]	-4	hSpCas9	negative selection	8865962
44275388	44275411	11	+	27260156	T47D	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.027502523642165433	[802]	[971,808,811,1094]	0	hSpCas9	negative selection	8865963
44310023	44310046	11	-	27260156	SU8686	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.16747714759637156	[715]	[756,697,671,1122]	3	hSpCas9	negative selection	8922930
44264907	44264930	11	-	27260156	SU8686	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	0.08005750676794421	[292]	[325,270,187,465]	1	hSpCas9	negative selection	8922931
44309849	44309872	11	-	27260156	SU8686	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.6092533824941563	[183]	[298,250,273,289]	8	hSpCas9	negative selection	8922932
44275393	44275416	11	-	27260156	SU8686	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.24449719874675624	[264]	[240,225,185,229]	-4	hSpCas9	negative selection	8987212
44264899	44264922	11	+	27260156	SU8686	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.18999830885582192	[11]	[2,8,8,38]	3	hSpCas9	negative selection	8987213
44275388	44275411	11	+	27260156	SU8686	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.09179082988292897	[802]	[760,614,678,978]	-2	hSpCas9	negative selection	8987214
44310023	44310046	11	-	27260156	SKES1	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.10423068684979331	[715]	[944,769,816,577]	2	hSpCas9	negative selection	9044181
44264907	44264930	11	-	27260156	SKES1	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.052508153500131605	[292]	[325,360,271,191]	-1	hSpCas9	negative selection	9044182
44309849	44309872	11	-	27260156	SKES1	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.3241989368928617	[183]	[234,260,292,141]	6	hSpCas9	negative selection	9044183
44275393	44275416	11	-	27260156	SKES1	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.50118081951709	[264]	[230,189,152,178]	-8	hSpCas9	negative selection	9108463
44264899	44264922	11	+	27260156	SKES1	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.0016039650517614135	[11]	[6,36,0,5]	0	hSpCas9	negative selection	9108464
44275388	44275411	11	+	27260156	SKES1	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.3135018982660796	[802]	[607,1021,550,454]	-6	hSpCas9	negative selection	9108465
44310023	44310046	11	-	27260156	TOV112D	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.15588641991049484	[715]	[540,867,706,507]	-3	hSpCas9	negative selection	9165432
44264907	44264930	11	-	27260156	TOV112D	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.06274291396426812	[292]	[264,234,157,447]	-1	hSpCas9	negative selection	9165433
44309849	44309872	11	-	27260156	TOV112D	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.5677393189476776	[183]	[118,380,270,332]	8	hSpCas9	negative selection	9165434
44275393	44275416	11	-	27260156	TOV112D	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	0.18954549139468324	[264]	[250,384,355,235]	3	hSpCas9	negative selection	9229714
44264899	44264922	11	+	27260156	TOV112D	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.0986762290662817	[11]	[25,1,9,5]	-2	hSpCas9	negative selection	9229715
44275388	44275411	11	+	27260156	TOV112D	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.10015751149426233	[802]	[718,640,807,800]	-2	hSpCas9	negative selection	9229716
44310023	44310046	11	-	27260156	TC71	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	-0.06796353231268837	[715]	[673,673,788,794]	-2	hSpCas9	negative selection	9286683
44264907	44264930	11	-	27260156	TC71	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.631285936291457	[292]	[164,216,167,266]	-9	hSpCas9	negative selection	9286684
44309849	44309872	11	-	27260156	TC71	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.13031280725460603	[183]	[257,274,134,195]	3	hSpCas9	negative selection	9286685
44275393	44275416	11	-	27260156	TC71	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.1304137779905894	[264]	[208,234,260,338]	-3	hSpCas9	negative selection	9350965
44264899	44264922	11	+	27260156	TC71	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	0.3078683987398101	[11]	[0,29,6,26]	7	hSpCas9	negative selection	9350966
44275388	44275411	11	+	27260156	TC71	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	-0.331332197689152	[802]	[702,642,718,668]	-7	hSpCas9	negative selection	9350967
44310023	44310046	11	-	27260156	TC32	viability	CGTCTCTTACTGCGAGTCGCCGG	ALX4	ENSG00000052850	0.07877217292058303	[715]	[794,447,771,894]	1	hSpCas9	negative selection	9407934
44264907	44264930	11	-	27260156	TC32	viability	CCGCAAGACCTCGAGCATCGCGG	ALX4	ENSG00000052850	-0.5112620515437486	[292]	[168,90,257,303]	-7	hSpCas9	negative selection	9407935
44309849	44309872	11	-	27260156	TC32	viability	CCGTTACGGCGCTGGGCAGCAGG	ALX4	ENSG00000052850	0.357075332904105	[183]	[193,93,396,274]	6	hSpCas9	negative selection	9407936
44275393	44275416	11	-	27260156	TC32	viability	ACTACCCAGACGTGTATGCGCGG	ALX4	ENSG00000052850	-0.027032360687549217	[264]	[192,170,373,284]	0	hSpCas9	negative selection	9472216
44264899	44264922	11	+	27260156	TC32	viability	GCGGAGGGCCGCGATGCTCGAGG	ALX4	ENSG00000052850	-0.09592067231511425	[11]	[17,1,17,6]	-2	hSpCas9	negative selection	9472217
44275388	44275411	11	+	27260156	TC32	viability	TGTTCCCGCGCATACACGTCTGG	ALX4	ENSG00000052850	0.05141670477874116	[802]	[771,503,1077,892]	0	hSpCas9	negative selection	9472218
44264931	44264954	11	-	27869803	HPAFII	viability after 27 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.677935425769089	[233]	[150,234,NaN]	5	hSpCas9	negative selection	9541509
44264945	44264968	11	+	27869803	HPAFII	viability after 27 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.6372640167604157	[197]	[168,155,NaN]	5	hSpCas9	negative selection	9541510
44275572	44275595	11	-	27869803	HPAFII	viability after 27 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.19961397003526293	[501]	[243,217,NaN]	-1	hSpCas9	negative selection	9541511
44275604	44275627	11	+	27869803	HPAFII	viability after 27 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.5476184801199104	[252]	[174,20,NaN]	-4	hSpCas9	negative selection	9541512
44309974	44309997	11	+	27869803	HPAFII	viability after 27 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.48633655581212554	[669]	[403,567,NaN]	4	hSpCas9	negative selection	9541513
44310004	44310027	11	+	27869803	HPAFII	viability after 27 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	-0.9691186109239032	[217]	[51,63,NaN]	-6	hSpCas9	negative selection	9541514
44264931	44264954	11	-	27869803	HPAFII	viability after 15 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.4156248081989179	[233]	[184,428,NaN]	5	hSpCas9	negative selection	9623958
44264945	44264968	11	+	27869803	HPAFII	viability after 15 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.371337301224194	[197]	[413,188,NaN]	4	hSpCas9	negative selection	9623959
44275572	44275595	11	-	27869803	HPAFII	viability after 15 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.7489613066479495	[501]	[267,353,NaN]	-7	hSpCas9	negative selection	9623960
44275604	44275627	11	+	27869803	HPAFII	viability after 15 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.5678178596982915	[252]	[233,151,NaN]	-6	hSpCas9	negative selection	9623961
44309974	44309997	11	+	27869803	HPAFII	viability after 15 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.08876637594069248	[669]	[922,667,NaN]	1	hSpCas9	negative selection	9623962
44310004	44310027	11	+	27869803	HPAFII	viability after 15 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	-1.4447680213136278	[217]	[90,82,NaN]	-8	hSpCas9	negative selection	9623963
44264931	44264954	11	-	27869803	ASPC1	viability after 36 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.10566206381914547	[522]	[334,144,137]	1	hSpCas9	negative selection	9706407
44264945	44264968	11	+	27869803	ASPC1	viability after 36 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	1.0451359327083314	[654]	[853,211,404]	8	hSpCas9	negative selection	9706408
44275572	44275595	11	-	27869803	ASPC1	viability after 36 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.6034790390636395	[990]	[395,740,439]	6	hSpCas9	negative selection	9706409
44275604	44275627	11	+	27869803	ASPC1	viability after 36 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.47937801458072105	[633]	[67,136,237]	-5	hSpCas9	negative selection	9706410
44309974	44309997	11	+	27869803	ASPC1	viability after 36 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.02886013130926246	[1444]	[516,319,661]	0	hSpCas9	negative selection	9706411
44310004	44310027	11	+	27869803	ASPC1	viability after 36 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	0.23914712960694828	[363]	[34,372,51]	2	hSpCas9	negative selection	9706412
44264931	44264954	11	-	27869803	PATU8988S	viability after 35 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.8339530261660472	[516]	[225,516,NaN]	8	hSpCas9	negative selection	9788856
44264945	44264968	11	+	27869803	PATU8988S	viability after 35 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.3095090399324659	[565]	[283,280,NaN]	3	hSpCas9	negative selection	9788857
44275572	44275595	11	-	27869803	PATU8988S	viability after 35 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.4495844305278075	[854]	[318,184,NaN]	-4	hSpCas9	negative selection	9788858
44275604	44275627	11	+	27869803	PATU8988S	viability after 35 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	0.09314061038974192	[420]	[121,239,NaN]	1	hSpCas9	negative selection	9788859
44309974	44309997	11	+	27869803	PATU8988S	viability after 35 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	-0.18871804377509327	[1326]	[432,504,NaN]	-2	hSpCas9	negative selection	9788860
44310004	44310027	11	+	27869803	PATU8988S	viability after 35 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	-0.7581208055809616	[360]	[70,100,NaN]	-6	hSpCas9	negative selection	9788861
44264931	44264954	11	-	27869803	PATU8988S	viability after 31 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.4403854941884806	[516]	[178,407,NaN]	5	hSpCas9	negative selection	9871305
44264945	44264968	11	+	27869803	PATU8988S	viability after 31 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.13804844733812863	[565]	[206,300,NaN]	1	hSpCas9	negative selection	9871306
44275572	44275595	11	-	27869803	PATU8988S	viability after 31 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.13963937931656234	[854]	[279,346,NaN]	-1	hSpCas9	negative selection	9871307
44275604	44275627	11	+	27869803	PATU8988S	viability after 31 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.15477735701063605	[420]	[119,189,NaN]	-2	hSpCas9	negative selection	9871308
44309974	44309997	11	+	27869803	PATU8988S	viability after 31 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.05666455136528903	[1326]	[398,742,NaN]	0	hSpCas9	negative selection	9871309
44310004	44310027	11	+	27869803	PATU8988S	viability after 31 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	-0.949231641190357	[360]	[30,129,NaN]	-7	hSpCas9	negative selection	9871310
44264931	44264954	11	-	27869803	HPAFII	viability after 35 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.6725173139023418	[233]	[161,218,NaN]	4	hSpCas9	negative selection	9953754
44264945	44264968	11	+	27869803	HPAFII	viability after 35 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.11099465531489114	[197]	[143,67,NaN]	0	hSpCas9	negative selection	9953755
44275572	44275595	11	-	27869803	HPAFII	viability after 35 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	-0.4953227650652854	[501]	[160,201,NaN]	-3	hSpCas9	negative selection	9953756
44275604	44275627	11	+	27869803	HPAFII	viability after 35 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-1.4067058307049007	[252]	[76,15,NaN]	-6	hSpCas9	negative selection	9953757
44309974	44309997	11	+	27869803	HPAFII	viability after 35 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.28372401908185596	[669]	[212,637,NaN]	1	hSpCas9	negative selection	9953758
44310004	44310027	11	+	27869803	HPAFII	viability after 35 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	-1.3025030087553167	[217]	[0,93,NaN]	-6	hSpCas9	negative selection	9953759
44264931	44264954	11	-	27869803	HPAFII	viability after 31 days	CTACGAGCTCAACGGCGAGCCGG	ALX4	ENSG00000052850	0.5941835357958317	[233]	[147,252,NaN]	4	hSpCas9	negative selection	10036203
44264945	44264968	11	+	27869803	HPAFII	viability after 31 days	AGCTCGTAGCCATTGAGGCCTGG	ALX4	ENSG00000052850	0.761669734321069	[197]	[241,129,NaN]	5	hSpCas9	negative selection	10036204
44275572	44275595	11	-	27869803	HPAFII	viability after 31 days	CAGCTACCTGAGTGTCAAGGAGG	ALX4	ENSG00000052850	0.13152207180983067	[501]	[288,329,NaN]	0	hSpCas9	negative selection	10036205
44275604	44275627	11	+	27869803	HPAFII	viability after 31 days	CCCACAGTGTCAGAGTCAGGGGG	ALX4	ENSG00000052850	-0.6972340333858751	[252]	[144,24,NaN]	-4	hSpCas9	negative selection	10036206
44309974	44309997	11	+	27869803	HPAFII	viability after 31 days	CCCTCCCGACTCTGCGACACCGG	ALX4	ENSG00000052850	0.5968960284932223	[669]	[349,806,NaN]	4	hSpCas9	negative selection	10036207
44310004	44310027	11	+	27869803	HPAFII	viability after 31 days	TAGGCGTCCATGGCAGCGGCCGG	ALX4	ENSG00000052850	-1.487139477340543	[217]	[57,27,NaN]	-7	hSpCas9	negative selection	10036208
44275477	44275500	11	-	28162770	P31FUJ	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	0.45308920515755846	[91]	[147]	5	hSpCas9	negative selection	10109796
44309606	44309629	11	+	28162770	P31FUJ	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.13992449000650087	[345]	[447]	1	hSpCas9	negative selection	10109797
44309638	44309661	11	-	28162770	P31FUJ	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.6619257524855624	[134]	[250]	7	hSpCas9	negative selection	10109798
44275359	44275382	11	-	28162770	P31FUJ	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.28427121939608013	[427]	[412]	-3	hSpCas9	negative selection	10109799
44267521	44267544	11	+	28162770	P31FUJ	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-1.0900620322982966	[124]	[68]	-6	hSpCas9	negative selection	10109800
44310000	44310023	11	+	28162770	P31FUJ	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.21931897505075654	[212]	[214]	-2	hSpCas9	negative selection	10109801
44309892	44309915	11	+	28162770	P31FUJ	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	-0.007735648779605309	[384]	[449]	0	hSpCas9	negative selection	10109802
44309874	44309897	11	-	28162770	P31FUJ	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.5963429229922721	[290]	[516]	6	hSpCas9	negative selection	10109803
44309815	44309838	11	+	28162770	P31FUJ	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.27462238010900575	[699]	[679]	-3	hSpCas9	negative selection	10109804
44309618	44309641	11	-	28162770	P31FUJ	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	1.1042327828631922	[37]	[95]	9	hSpCas9	negative selection	10109805
44275477	44275500	11	-	28162770	TF1	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10279162
44309606	44309629	11	+	28162770	TF1	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	NaN	[NaN]	[362]	1	hSpCas9	negative selection	10279163
44309638	44309661	11	-	28162770	TF1	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10279164
44275359	44275382	11	-	28162770	TF1	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	NaN	[NaN]	[248]	1	hSpCas9	negative selection	10279165
44267521	44267544	11	+	28162770	TF1	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10279166
44310000	44310023	11	+	28162770	TF1	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	NaN	[NaN]	[124]	1	hSpCas9	negative selection	10279167
44309892	44309915	11	+	28162770	TF1	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	NaN	[NaN]	[235]	1	hSpCas9	negative selection	10279168
44309874	44309897	11	-	28162770	TF1	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	NaN	[NaN]	[369]	1	hSpCas9	negative selection	10279169
44309815	44309838	11	+	28162770	TF1	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	NaN	[NaN]	[584]	1	hSpCas9	negative selection	10279170
44309618	44309641	11	-	28162770	TF1	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10279171
44275477	44275500	11	-	28162770	SKM1	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	0.4190064014817896	[21]	[51]	4	hSpCas9	negative selection	10448528
44309606	44309629	11	+	28162770	SKM1	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.2744611414792856	[93]	[200]	2	hSpCas9	negative selection	10448529
44309638	44309661	11	-	28162770	SKM1	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.4454786128429804	[26]	[64]	4	hSpCas9	negative selection	10448530
44275359	44275382	11	-	28162770	SKM1	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.6184683039368737	[131]	[151]	-5	hSpCas9	negative selection	10448531
44267521	44267544	11	+	28162770	SKM1	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-0.014646775964401393	[43]	[76]	0	hSpCas9	negative selection	10448532
44310000	44310023	11	+	28162770	SKM1	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.4894263589351347	[53]	[67]	-4	hSpCas9	negative selection	10448533
44309892	44309915	11	+	28162770	SKM1	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.15168702486214725	[82]	[162]	1	hSpCas9	negative selection	10448534
44309874	44309897	11	-	28162770	SKM1	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.38532327522550086	[54]	[126]	4	hSpCas9	negative selection	10448535
44309815	44309838	11	+	28162770	SKM1	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.3220143263234414	[168]	[238]	-3	hSpCas9	negative selection	10448536
44309618	44309641	11	-	28162770	SKM1	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	-0.8220016980220057	[8]	[8]	-6	hSpCas9	negative selection	10448537
44275477	44275500	11	-	28162770	SKM1	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	0.4190064014817896	[21]	[51]	4	hSpCas9	negative selection	10617894
44309606	44309629	11	+	28162770	SKM1	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.2744611414792856	[93]	[200]	2	hSpCas9	negative selection	10617895
44309638	44309661	11	-	28162770	SKM1	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.4454786128429804	[26]	[64]	4	hSpCas9	negative selection	10617896
44275359	44275382	11	-	28162770	SKM1	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.6184683039368737	[131]	[151]	-5	hSpCas9	negative selection	10617897
44267521	44267544	11	+	28162770	SKM1	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-0.014646775964401393	[43]	[76]	0	hSpCas9	negative selection	10617898
44310000	44310023	11	+	28162770	SKM1	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.4894263589351347	[53]	[67]	-4	hSpCas9	negative selection	10617899
44309892	44309915	11	+	28162770	SKM1	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.15168702486214725	[82]	[162]	1	hSpCas9	negative selection	10617900
44309874	44309897	11	-	28162770	SKM1	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.38532327522550086	[54]	[126]	4	hSpCas9	negative selection	10617901
44309815	44309838	11	+	28162770	SKM1	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.3220143263234414	[168]	[238]	-3	hSpCas9	negative selection	10617902
44309618	44309641	11	-	28162770	SKM1	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	-0.8220016980220057	[8]	[8]	-6	hSpCas9	negative selection	10617903
44275477	44275500	11	-	28162770	PL21	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	-0.12178848039804235	[139]	[55]	-1	hSpCas9	negative selection	10787260
44309606	44309629	11	+	28162770	PL21	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.3106161508508898	[288]	[155]	2	hSpCas9	negative selection	10787261
44309638	44309661	11	-	28162770	PL21	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.009808402385170778	[88]	[38]	0	hSpCas9	negative selection	10787262
44275359	44275382	11	-	28162770	PL21	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.48435855978275033	[404]	[125]	-3	hSpCas9	negative selection	10787263
44267521	44267544	11	+	28162770	PL21	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	0.322623621014315	[157]	[85]	3	hSpCas9	negative selection	10787264
44310000	44310023	11	+	28162770	PL21	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.2981147740526177	[184]	[98]	2	hSpCas9	negative selection	10787265
44309892	44309915	11	+	28162770	PL21	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.5693734241550393	[239]	[154]	5	hSpCas9	negative selection	10787266
44309874	44309897	11	-	28162770	PL21	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.32846371146485964	[171]	[93]	3	hSpCas9	negative selection	10787267
44309815	44309838	11	+	28162770	PL21	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	0.5956809381423669	[446]	[293]	5	hSpCas9	negative selection	10787268
44309618	44309641	11	-	28162770	PL21	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	-0.5003001036517722	[25]	[7]	-4	hSpCas9	negative selection	10787269
44275477	44275500	11	-	28162770	P31FUJ	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	0.45308920515755846	[91]	[147]	5	hSpCas9	negative selection	10956626
44309606	44309629	11	+	28162770	P31FUJ	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.13992449000650087	[345]	[447]	1	hSpCas9	negative selection	10956627
44309638	44309661	11	-	28162770	P31FUJ	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.6619257524855624	[134]	[250]	7	hSpCas9	negative selection	10956628
44275359	44275382	11	-	28162770	P31FUJ	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.28427121939608013	[427]	[412]	-3	hSpCas9	negative selection	10956629
44267521	44267544	11	+	28162770	P31FUJ	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-1.0900620322982966	[124]	[68]	-6	hSpCas9	negative selection	10956630
44310000	44310023	11	+	28162770	P31FUJ	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.21931897505075654	[212]	[214]	-2	hSpCas9	negative selection	10956631
44309892	44309915	11	+	28162770	P31FUJ	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	-0.007735648779605309	[384]	[449]	0	hSpCas9	negative selection	10956632
44309874	44309897	11	-	28162770	P31FUJ	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.5963429229922721	[290]	[516]	6	hSpCas9	negative selection	10956633
44309815	44309838	11	+	28162770	P31FUJ	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.27462238010900575	[699]	[679]	-3	hSpCas9	negative selection	10956634
44309618	44309641	11	-	28162770	P31FUJ	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	1.1042327828631922	[37]	[95]	9	hSpCas9	negative selection	10956635
44275477	44275500	11	-	28162770	OCIAML5	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	-0.36174094428091585	[41]	[58]	-3	hSpCas9	negative selection	11125992
44309606	44309629	11	+	28162770	OCIAML5	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.3833820032978973	[219]	[517]	3	hSpCas9	negative selection	11125993
44309638	44309661	11	-	28162770	OCIAML5	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.7224035560395167	[45]	[136]	6	hSpCas9	negative selection	11125994
44275359	44275382	11	-	28162770	OCIAML5	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	0.1659448371203216	[198]	[402]	1	hSpCas9	negative selection	11125995
44267521	44267544	11	+	28162770	OCIAML5	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	0.6666622314570725	[51]	[148]	6	hSpCas9	negative selection	11125996
44310000	44310023	11	+	28162770	OCIAML5	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.10045420073338945	[97]	[164]	0	hSpCas9	negative selection	11125997
44309892	44309915	11	+	28162770	OCIAML5	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.6839863293762126	[169]	[492]	6	hSpCas9	negative selection	11125998
44309874	44309897	11	-	28162770	OCIAML5	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.16083391784380918	[166]	[336]	1	hSpCas9	negative selection	11125999
44309815	44309838	11	+	28162770	OCIAML5	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.5778232737344802	[405]	[490]	-4	hSpCas9	negative selection	11126000
44309618	44309641	11	-	28162770	OCIAML5	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	2.440715178363849	[9]	[97]	9	hSpCas9	negative selection	11126001
44275477	44275500	11	-	28162770	EOL1	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	-0.038458020947263916	[153]	[78]	0	hSpCas9	negative selection	11295358
44309606	44309629	11	+	28162770	EOL1	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	1.073862493337561	[375]	[416]	8	hSpCas9	negative selection	11295359
44309638	44309661	11	-	28162770	EOL1	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	-0.34505928818674547	[175]	[72]	-3	hSpCas9	negative selection	11295360
44275359	44275382	11	-	28162770	EOL1	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.618745549849548	[818]	[280]	-4	hSpCas9	negative selection	11295361
44267521	44267544	11	+	28162770	EOL1	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-0.04630588276994885	[244]	[124]	0	hSpCas9	negative selection	11295362
44310000	44310023	11	+	28162770	EOL1	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.04158719276075394	[283]	[153]	0	hSpCas9	negative selection	11295363
44309892	44309915	11	+	28162770	EOL1	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	-0.9879893871791259	[447]	[118]	-6	hSpCas9	negative selection	11295364
44309874	44309897	11	-	28162770	EOL1	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.2377056568301647	[263]	[163]	2	hSpCas9	negative selection	11295365
44309815	44309838	11	+	28162770	EOL1	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.540833113397949	[728]	[263]	-4	hSpCas9	negative selection	11295366
44309618	44309641	11	-	28162770	EOL1	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	-0.07545222842946542	[41]	[20]	0	hSpCas9	negative selection	11295367
44275477	44275500	11	-	28162770	MOLM13	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	1.0603464188126592	[127]	[192]	7	hSpCas9	negative selection	11464724
44309606	44309629	11	+	28162770	MOLM13	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.7198685988693769	[392]	[467]	5	hSpCas9	negative selection	11464725
44309638	44309661	11	-	28162770	MOLM13	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	1.3698572985840523	[136]	[255]	9	hSpCas9	negative selection	11464726
44275359	44275382	11	-	28162770	MOLM13	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	0.2572874037898134	[588]	[508]	1	hSpCas9	negative selection	11464727
44267521	44267544	11	+	28162770	MOLM13	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	1.56274856788602	[205]	[439]	9	hSpCas9	negative selection	11464728
44310000	44310023	11	+	28162770	MOLM13	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.6715783642026186	[243]	[280]	5	hSpCas9	negative selection	11464729
44309892	44309915	11	+	28162770	MOLM13	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.773579484635062	[410]	[507]	6	hSpCas9	negative selection	11464730
44309874	44309897	11	-	28162770	MOLM13	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.7486984891063486	[241]	[293]	5	hSpCas9	negative selection	11464731
44309815	44309838	11	+	28162770	MOLM13	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.46328858571098364	[613]	[321]	-3	hSpCas9	negative selection	11464732
44309618	44309641	11	-	28162770	MOLM13	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	-3.269076212621627	[39]	[2]	-8	hSpCas9	negative selection	11464733
44275477	44275500	11	-	28162770	HEL	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	-0.6741182733395835	[141]	[56]	-4	hSpCas9	negative selection	11634090
44309606	44309629	11	+	28162770	HEL	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.3754921748796485	[342]	[284]	3	hSpCas9	negative selection	11634091
44309638	44309661	11	-	28162770	HEL	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	1.0721316242562706	[149]	[201]	8	hSpCas9	negative selection	11634092
44275359	44275382	11	-	28162770	HEL	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.15244137611114494	[530]	[305]	-1	hSpCas9	negative selection	11634093
44267521	44267544	11	+	28162770	HEL	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	0.7778264550335359	[162]	[178]	6	hSpCas9	negative selection	11634094
44310000	44310023	11	+	28162770	HEL	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.6922782928016722	[228]	[236]	6	hSpCas9	negative selection	11634095
44309892	44309915	11	+	28162770	HEL	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.4195804456653543	[313]	[268]	3	hSpCas9	negative selection	11634096
44309874	44309897	11	-	28162770	HEL	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.06084263432698431	[234]	[156]	0	hSpCas9	negative selection	11634097
44309815	44309838	11	+	28162770	HEL	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.10188033470928448	[629]	[375]	0	hSpCas9	negative selection	11634098
44309618	44309641	11	-	28162770	HEL	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	1.5377692723988146	[56]	[105]	9	hSpCas9	negative selection	11634099
44275477	44275500	11	-	28162770	MV411	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	-0.01934898991212619	[76]	[63]	0	hSpCas9	negative selection	11803456
44309606	44309629	11	+	28162770	MV411	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.03216956387970882	[302]	[260]	0	hSpCas9	negative selection	11803457
44309638	44309661	11	-	28162770	MV411	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.35304773874337403	[78]	[84]	3	hSpCas9	negative selection	11803458
44275359	44275382	11	-	28162770	MV411	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.40798743866251774	[492]	[312]	-3	hSpCas9	negative selection	11803459
44267521	44267544	11	+	28162770	MV411	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-0.8343565403808719	[126]	[59]	-5	hSpCas9	negative selection	11803460
44310000	44310023	11	+	28162770	MV411	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.6478650705505316	[185]	[99]	-4	hSpCas9	negative selection	11803461
44309892	44309915	11	+	28162770	MV411	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.3165300740557211	[264]	[277]	3	hSpCas9	negative selection	11803462
44309874	44309897	11	-	28162770	MV411	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.4806367270758061	[170]	[200]	4	hSpCas9	negative selection	11803463
44309815	44309838	11	+	28162770	MV411	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.1544588488080023	[509]	[385]	-1	hSpCas9	negative selection	11803464
44309618	44309641	11	-	28162770	MV411	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	0.24743755078277507	[37]	[37]	2	hSpCas9	negative selection	11803465
44275477	44275500	11	-	28162770	MONOMAC1	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	-0.40139534556573997	[52]	[45]	-3	hSpCas9	negative selection	11972822
44309606	44309629	11	+	28162770	MONOMAC1	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	1.0383822545731338	[188]	[444]	8	hSpCas9	negative selection	11972823
44309638	44309661	11	-	28162770	MONOMAC1	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	-0.5449601504798605	[55]	[43]	-4	hSpCas9	negative selection	11972824
44275359	44275382	11	-	28162770	MONOMAC1	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.2744413507451602	[267]	[253]	-2	hSpCas9	negative selection	11972825
44267521	44267544	11	+	28162770	MONOMAC1	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-0.7205988031165667	[91]	[63]	-5	hSpCas9	negative selection	11972826
44310000	44310023	11	+	28162770	MONOMAC1	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.46526774219476746	[114]	[181]	4	hSpCas9	negative selection	11972827
44309892	44309915	11	+	28162770	MONOMAC1	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	-0.005377553262713386	[182]	[208]	0	hSpCas9	negative selection	11972828
44309874	44309897	11	-	28162770	MONOMAC1	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.3879256536616027	[81]	[122]	4	hSpCas9	negative selection	11972829
44309815	44309838	11	+	28162770	MONOMAC1	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	0.7027214871851377	[364]	[680]	6	hSpCas9	negative selection	11972830
44309618	44309641	11	-	28162770	MONOMAC1	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	0.11330327355259673	[24]	[30]	1	hSpCas9	negative selection	11972831
44275477	44275500	11	-	28162770	OCIAML2	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	0.04874433385141819	[14]	[85]	0	hSpCas9	negative selection	12142188
44309606	44309629	11	+	28162770	OCIAML2	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.2842576769213072	[55]	[377]	2	hSpCas9	negative selection	12142189
44309638	44309661	11	-	28162770	OCIAML2	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	0.3367250968154429	[21]	[153]	3	hSpCas9	negative selection	12142190
44275359	44275382	11	-	28162770	OCIAML2	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	-0.6108074832904218	[80]	[293]	-4	hSpCas9	negative selection	12142191
44267521	44267544	11	+	28162770	OCIAML2	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-0.9718239682707197	[45]	[129]	-6	hSpCas9	negative selection	12142192
44310000	44310023	11	+	28162770	OCIAML2	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	-0.20010088286144306	[39]	[192]	-2	hSpCas9	negative selection	12142193
44309892	44309915	11	+	28162770	OCIAML2	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.712591998813609	[35]	[326]	7	hSpCas9	negative selection	12142194
44309874	44309897	11	-	28162770	OCIAML2	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.959358015502654	[26]	[290]	8	hSpCas9	negative selection	12142195
44309815	44309838	11	+	28162770	OCIAML2	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.4869316375712617	[88]	[351]	-4	hSpCas9	negative selection	12142196
44309618	44309641	11	-	28162770	OCIAML2	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	0.007417471562483069	[6]	[38]	0	hSpCas9	negative selection	12142197
44275477	44275500	11	-	28162770	OCIAML3	viability	GCAACAAGGGCAAGAAGCGGCGG	ALX4	ENSG00000052850	1.446406628121745	[21]	[180]	9	hSpCas9	negative selection	12311554
44309606	44309629	11	+	28162770	OCIAML3	viability	GAACCTGCAAGGCCGCGCTGTGG	ALX4	ENSG00000052850	0.23352516367107123	[70]	[251]	2	hSpCas9	negative selection	12311555
44309638	44309661	11	-	28162770	OCIAML3	viability	GGCAGCCTCAAACTCCAGGAAGG	ALX4	ENSG00000052850	1.646306689009547	[19]	[188]	9	hSpCas9	negative selection	12311556
44275359	44275382	11	-	28162770	OCIAML3	viability	CATGAGGACAGACCTCACTGAGG	ALX4	ENSG00000052850	0.7224139782566554	[104]	[522]	6	hSpCas9	negative selection	12311557
44267521	44267544	11	+	28162770	OCIAML3	viability	GAGGGGCAGCTCATATGCAGTGG	ALX4	ENSG00000052850	-0.4240826388818507	[35]	[80]	-3	hSpCas9	negative selection	12311558
44310000	44310023	11	+	28162770	OCIAML3	viability	GTAGTAGGCGTCCATGGCAGCGG	ALX4	ENSG00000052850	0.45038647903429035	[55]	[230]	4	hSpCas9	negative selection	12311559
44309892	44309915	11	+	28162770	OCIAML3	viability	GAATCCCTGTGCTTTGGCGGCGG	ALX4	ENSG00000052850	0.43214464753180515	[122]	[500]	4	hSpCas9	negative selection	12311560
44309874	44309897	11	-	28162770	OCIAML3	viability	GATTCGGGGACGCCAAGAGCCGG	ALX4	ENSG00000052850	0.7724860069966436	[50]	[262]	7	hSpCas9	negative selection	12311561
44309815	44309838	11	+	28162770	OCIAML3	viability	GCCCCAGCTCCACTCTCCAGGGG	ALX4	ENSG00000052850	-0.3221202279363964	[175]	[424]	-3	hSpCas9	negative selection	12311562
44309618	44309641	11	-	28162770	OCIAML3	viability	AGGCAGCAGCGGCCACAGCGCGG	ALX4	ENSG00000052850	1.575917361118149	[4]	[44]	9	hSpCas9	negative selection	12311563