Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:90806
• Symbol:ANGEL2
• Description:angel homolog 2

DataSource: http://genomecrispr.dkfz.de/#!/results/ANGEL2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
213013361	213013384	1	-	26472758	Jiyoye	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.21243326202217427	[294]	[191]	-1	hSpCas9	negative selection	6330
213005337	213005360	1	+	26472758	Jiyoye	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	-0.3171901758806993	[227]	[137]	-2	hSpCas9	negative selection	6331
213000345	213000368	1	-	26472758	Jiyoye	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.37860622930910237	[50]	[49]	3	hSpCas9	negative selection	6332
213015623	213015646	1	-	26472758	Jiyoye	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	-0.5241118684101121	[327]	[171]	-4	hSpCas9	negative selection	6333
213015614	213015637	1	+	26472758	Jiyoye	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.9315963402919788	[72]	[104]	6	hSpCas9	negative selection	6334
213005145	213005168	1	-	26472758	Jiyoye	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.03580835388400605	[140]	[108]	0	hSpCas9	negative selection	6335
212997213	212997236	1	+	26472758	Jiyoye	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.6615373685781409	[85]	[40]	-5	hSpCas9	negative selection	6336
213013129	213013152	1	-	26472758	Jiyoye	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.3078476597796557	[173]	[105]	-2	hSpCas9	negative selection	6337
213005214	213005237	1	-	26472758	Jiyoye	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.23029761942179428	[51]	[45]	1	hSpCas9	negative selection	6338
213013218	213013241	1	+	26472758	Jiyoye	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-1.1200716213589954	[48]	[16]	-6	hSpCas9	negative selection	6339
213013361	213013384	1	-	26472758	KBM7	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.4095096166522574	[985,545]	[386,154]	-4	hSpCas9	negative selection	197448
213005337	213005360	1	+	26472758	KBM7	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.6769541917768801	[596,537]	[380,466]	7	hSpCas9	negative selection	197449
213000345	213000368	1	-	26472758	KBM7	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	1.8959348157234581	[267,158]	[154,553]	9	hSpCas9	negative selection	197450
213015623	213015646	1	-	26472758	KBM7	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.19777619388109524	[876,746]	[550,333]	2	hSpCas9	negative selection	197451
213015614	213015637	1	+	26472758	KBM7	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.12216704266372289	[361,379]	[195,186]	1	hSpCas9	negative selection	197452
213005145	213005168	1	-	26472758	KBM7	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	-0.033893442136216194	[555,454]	[307,161]	0	hSpCas9	negative selection	197453
212997213	212997236	1	+	26472758	KBM7	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	1.2436996146181687	[202,156]	[136,253]	9	hSpCas9	negative selection	197454
213013129	213013152	1	-	26472758	KBM7	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.4444132522508341	[587,687]	[536,302]	5	hSpCas9	negative selection	197455
213005214	213005237	1	-	26472758	KBM7	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.45585160146811476	[324,286]	[299,104]	5	hSpCas9	negative selection	197456
213013218	213013241	1	+	26472758	KBM7	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	1.032691980267375	[55,55]	[79,30]	9	hSpCas9	negative selection	197457
213013361	213013384	1	-	26472758	Raji	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	0.4444185226511703	[341]	[107]	4	hSpCas9	negative selection	388566
213005337	213005360	1	+	26472758	Raji	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	-0.3615208358839801	[381]	[68]	-3	hSpCas9	negative selection	388567
213000345	213000368	1	-	26472758	Raji	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.7986308292339704	[108]	[43]	7	hSpCas9	negative selection	388568
213015623	213015646	1	-	26472758	Raji	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.6790492134812978	[435]	[161]	6	hSpCas9	negative selection	388569
213015614	213015637	1	+	26472758	Raji	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.9605421470443283	[154]	[69]	8	hSpCas9	negative selection	388570
213005145	213005168	1	-	26472758	Raji	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	-0.32212444671357765	[166]	[30]	-3	hSpCas9	negative selection	388571
212997213	212997236	1	+	26472758	Raji	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.7670855825425416	[131]	[17]	-5	hSpCas9	negative selection	388572
213013129	213013152	1	-	26472758	Raji	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.46889163823564833	[301]	[96]	4	hSpCas9	negative selection	388573
213005214	213005237	1	-	26472758	Raji	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.6022747127968714	[313]	[47]	-5	hSpCas9	negative selection	388574
213013218	213013241	1	+	26472758	Raji	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-0.16563495903281655	[57]	[11]	-1	hSpCas9	negative selection	388575
213013361	213013384	1	-	26472758	K562	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-1.4194289372957436	[544]	[171]	-6	hSpCas9	negative selection	579684
213005337	213005360	1	+	26472758	K562	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	-0.24029229941920813	[402]	[287]	-2	hSpCas9	negative selection	579685
213000345	213000368	1	-	26472758	K562	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.8318202738390205	[196]	[295]	7	hSpCas9	negative selection	579686
213015623	213015646	1	-	26472758	K562	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	-0.3206167291670702	[718]	[485]	-2	hSpCas9	negative selection	579687
213015614	213015637	1	+	26472758	K562	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-0.7904667899774117	[292]	[142]	-5	hSpCas9	negative selection	579688
213005145	213005168	1	-	26472758	K562	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.20182685094197883	[549]	[533]	1	hSpCas9	negative selection	579689
212997213	212997236	1	+	26472758	K562	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.3303919507762996	[227]	[241]	2	hSpCas9	negative selection	579690
213013129	213013152	1	-	26472758	K562	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.3361817063504118	[334]	[356]	2	hSpCas9	negative selection	579691
213005214	213005237	1	-	26472758	K562	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.5620594641507112	[336]	[419]	4	hSpCas9	negative selection	579692
213013218	213013241	1	+	26472758	K562	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-3.028599766739969	[57]	[5]	-8	hSpCas9	negative selection	579693
212997213	212997236	1	+	26627737	DLD1	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.029637587774434593	[141]	[10,19,95]	0	hSpCas9	negative selection	769070
213005214	213005237	1	-	26627737	DLD1	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.3410706573167384	[431]	[87,92,133]	-4	hSpCas9	negative selection	769071
213008260	213008283	1	+	26627737	DLD1	viability	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-0.011442357577622575	[133]	[29,34,56]	0	hSpCas9	negative selection	769072
213008276	213008299	1	-	26627737	DLD1	viability	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.04309367961189864	[344]	[94,109,125]	0	hSpCas9	negative selection	769073
213013302	213013325	1	-	26627737	DLD1	viability	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	-0.04404828342350653	[140]	[44,56,28]	0	hSpCas9	negative selection	769074
213015660	213015683	1	-	26627737	DLD1	viability	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-0.14800294833047078	[241]	[62,55,82]	-1	hSpCas9	negative selection	769075
212997213	212997236	1	+	26627737	GBM cells	viability after 5 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.46695756758927365	[124]	[45,50]	-6	hSpCas9	negative selection	851385
213005214	213005237	1	-	26627737	GBM cells	viability after 5 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.32754591604895417	[295]	[129,122]	-5	hSpCas9	negative selection	851386
213008260	213008283	1	+	26627737	GBM cells	viability after 5 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.33007103952780636	[88]	[47,71]	5	hSpCas9	negative selection	851387
213008276	213008299	1	-	26627737	GBM cells	viability after 5 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.21090940306706563	[190]	[71,104]	-3	hSpCas9	negative selection	851388
213013302	213013325	1	-	26627737	GBM cells	viability after 5 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	-0.16667446674189101	[134]	[70,57]	-3	hSpCas9	negative selection	851389
213015660	213015683	1	-	26627737	GBM cells	viability after 5 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	0.24683717830599217	[87]	[55,55]	4	hSpCas9	negative selection	851390
212997213	212997236	1	+	26627737	GBM cells	viability after 13 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.017591970625867148	[124]	[66,66]	0	hSpCas9	negative selection	933700
213005214	213005237	1	-	26627737	GBM cells	viability after 13 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.17119279045360009	[295]	[167,121]	-2	hSpCas9	negative selection	933701
213008260	213008283	1	+	26627737	GBM cells	viability after 13 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.13928528768539272	[88]	[77,32]	1	hSpCas9	negative selection	933702
213008276	213008299	1	-	26627737	GBM cells	viability after 13 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.50390355690547	[190]	[98,51]	-5	hSpCas9	negative selection	933703
213013302	213013325	1	-	26627737	GBM cells	viability after 13 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	-0.06028615325145714	[134]	[88,54]	0	hSpCas9	negative selection	933704
213015660	213015683	1	-	26627737	GBM cells	viability after 13 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-0.010826693060175918	[87]	[69,28]	0	hSpCas9	negative selection	933705
212997213	212997236	1	+	26627737	GBM cells	viability after 21 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.14669019558416418	[124]	[64,57]	-1	hSpCas9	negative selection	1016015
213005214	213005237	1	-	26627737	GBM cells	viability after 21 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-1.2316560865743567	[295]	[68,67]	-7	hSpCas9	negative selection	1016016
213008260	213008283	1	+	26627737	GBM cells	viability after 21 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-0.17821018034051672	[88]	[48,36]	-2	hSpCas9	negative selection	1016017
213008276	213008299	1	-	26627737	GBM cells	viability after 21 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.45649723342917475	[190]	[144,139]	5	hSpCas9	negative selection	1016018
213013302	213013325	1	-	26627737	GBM cells	viability after 21 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.5390301357368295	[134]	[104,107]	5	hSpCas9	negative selection	1016019
213015660	213015683	1	-	26627737	GBM cells	viability after 21 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	0.5415867482534568	[87]	[90,49]	5	hSpCas9	negative selection	1016020
212997213	212997236	1	+	26627737	RPE1	viability after 9 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.7584664996142352	[432]	[141,341]	5	hSpCas9	negative selection	1098330
213005214	213005237	1	-	26627737	RPE1	viability after 9 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	1.0169312428894726	[670]	[411,441]	6	hSpCas9	negative selection	1098331
213008260	213008283	1	+	26627737	RPE1	viability after 9 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.1907595125642576	[334]	[96,148]	1	hSpCas9	negative selection	1098332
213008276	213008299	1	-	26627737	RPE1	viability after 9 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.6877414648656088	[1122]	[71,406]	-5	hSpCas9	negative selection	1098333
213013302	213013325	1	-	26627737	RPE1	viability after 9 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.0245052677815791	[252]	[161,159]	6	hSpCas9	negative selection	1098334
213015660	213015683	1	-	26627737	RPE1	viability after 9 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-0.06026850239495962	[470]	[102,190]	0	hSpCas9	negative selection	1098335
212997213	212997236	1	+	26627737	RPE1	viability after 12 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.6033962980907108	[432]	[167,185]	4	hSpCas9	negative selection	1180645
213005214	213005237	1	-	26627737	RPE1	viability after 12 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.8922360906239448	[670]	[235,438]	5	hSpCas9	negative selection	1180646
213008260	213008283	1	+	26627737	RPE1	viability after 12 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.1411931480934292	[334]	[90,107]	1	hSpCas9	negative selection	1180647
213008276	213008299	1	-	26627737	RPE1	viability after 12 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.7822908774148881	[1122]	[121,231]	-5	hSpCas9	negative selection	1180648
213013302	213013325	1	-	26627737	RPE1	viability after 12 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.041222662726513	[252]	[152,125]	6	hSpCas9	negative selection	1180649
213015660	213015683	1	-	26627737	RPE1	viability after 12 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-1.2301118055227707	[470]	[68,37]	-7	hSpCas9	negative selection	1180650
212997213	212997236	1	+	26627737	RPE1	viability after 15 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.42618356961824555	[432]	[159,168]	2	hSpCas9	negative selection	1262960
213005214	213005237	1	-	26627737	RPE1	viability after 15 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	1.669217084859828	[670]	[452,748]	8	hSpCas9	negative selection	1262961
213008260	213008283	1	+	26627737	RPE1	viability after 15 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.8121098203476462	[334]	[200,132]	5	hSpCas9	negative selection	1262962
213008276	213008299	1	-	26627737	RPE1	viability after 15 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.32299138950119066	[1122]	[87,413]	-2	hSpCas9	negative selection	1262963
213013302	213013325	1	-	26627737	RPE1	viability after 15 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.6472463507394132	[252]	[78,143]	4	hSpCas9	negative selection	1262964
213015660	213015683	1	-	26627737	RPE1	viability after 15 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-0.034889198516557696	[470]	[98,159]	0	hSpCas9	negative selection	1262965
212997213	212997236	1	+	26627737	RPE1	viability after 18 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.7394764623039376	[432]	[124,269]	4	hSpCas9	negative selection	1345275
213005214	213005237	1	-	26627737	RPE1	viability after 18 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	1.361277138208672	[670]	[529,395]	7	hSpCas9	negative selection	1345276
213008260	213008283	1	+	26627737	RPE1	viability after 18 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.7325194335918818	[334]	[170,127]	4	hSpCas9	negative selection	1345277
213008276	213008299	1	-	26627737	RPE1	viability after 18 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.2175603028768346	[1122]	[118,411]	-1	hSpCas9	negative selection	1345278
213013302	213013325	1	-	26627737	RPE1	viability after 18 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.5749043383671775	[252]	[258,143]	8	hSpCas9	negative selection	1345279
213015660	213015683	1	-	26627737	RPE1	viability after 18 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-0.45495295174960415	[470]	[113,69]	-3	hSpCas9	negative selection	1345280
212997213	212997236	1	+	26627737	HeLa	viability after 8 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.02311350682413238	[117]	[91,1,69]	0	hSpCas9	negative selection	1427590
213005214	213005237	1	-	26627737	HeLa	viability after 8 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.8926120672224223	[554]	[136,142,112]	-7	hSpCas9	negative selection	1427591
213008260	213008283	1	+	26627737	HeLa	viability after 8 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	1.3449966724725608	[42]	[59,17,65]	8	hSpCas9	negative selection	1427592
213008276	213008299	1	-	26627737	HeLa	viability after 8 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.07529304443302154	[268]	[82,160,84]	0	hSpCas9	negative selection	1427593
213013302	213013325	1	-	26627737	HeLa	viability after 8 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.3066560311143394	[99]	[83,159,75]	8	hSpCas9	negative selection	1427594
213015660	213015683	1	-	26627737	HeLa	viability after 8 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	0.8745684995852521	[72]	[29,57,78]	7	hSpCas9	negative selection	1427595
212997213	212997236	1	+	26627737	HeLa	viability after 12 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.48216898395005825	[117]	[86,19,102]	4	hSpCas9	negative selection	1509905
213005214	213005237	1	-	26627737	HeLa	viability after 12 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.35075689450354847	[554]	[223,187,127]	-3	hSpCas9	negative selection	1509906
213008260	213008283	1	+	26627737	HeLa	viability after 12 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-0.1584737303732373	[42]	[3,0,43]	-1	hSpCas9	negative selection	1509907
213008276	213008299	1	-	26627737	HeLa	viability after 12 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.71587611029589	[268]	[111,51,41]	-6	hSpCas9	negative selection	1509908
213013302	213013325	1	-	26627737	HeLa	viability after 12 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.451009622771529	[99]	[128,116,92]	8	hSpCas9	negative selection	1509909
213015660	213015683	1	-	26627737	HeLa	viability after 12 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	1.8479355051127155	[72]	[157,91,78]	9	hSpCas9	negative selection	1509910
212997213	212997236	1	+	26627737	HeLa	viability after 15 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.44991536966921064	[117]	[18,35,51]	-4	hSpCas9	negative selection	1592220
213005214	213005237	1	-	26627737	HeLa	viability after 15 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.7955897173733839	[554]	[33,308,41]	-6	hSpCas9	negative selection	1592221
213008260	213008283	1	+	26627737	HeLa	viability after 15 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	1.5188285862112358	[42]	[62,28,58]	8	hSpCas9	negative selection	1592222
213008276	213008299	1	-	26627737	HeLa	viability after 15 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.1303211637466774	[268]	[160,90,105]	1	hSpCas9	negative selection	1592223
213013302	213013325	1	-	26627737	HeLa	viability after 15 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.5138939401358043	[99]	[110,155,78]	8	hSpCas9	negative selection	1592224
213015660	213015683	1	-	26627737	HeLa	viability after 15 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	1.273578417586663	[72]	[14,168,28]	8	hSpCas9	negative selection	1592225
212997213	212997236	1	+	26627737	HeLa	viability after 18 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.4540447668440182	[117]	[9,32,51]	-4	hSpCas9	negative selection	1674535
213005214	213005237	1	-	26627737	HeLa	viability after 18 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.7501635243466992	[554]	[21,266,41]	-6	hSpCas9	negative selection	1674536
213008260	213008283	1	+	26627737	HeLa	viability after 18 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	1.5925945816416025	[42]	[48,21,58]	8	hSpCas9	negative selection	1674537
213008276	213008299	1	-	26627737	HeLa	viability after 18 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.15056062396574155	[268]	[109,76,105]	1	hSpCas9	negative selection	1674538
213013302	213013325	1	-	26627737	HeLa	viability after 18 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.560253861599384	[99]	[81,128,78]	8	hSpCas9	negative selection	1674539
213015660	213015683	1	-	26627737	HeLa	viability after 18 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	1.3439549883516968	[72]	[12,144,28]	8	hSpCas9	negative selection	1674540
212997213	212997236	1	+	26627737	HCT116	viability after 6 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.6688554934721045	[320]	[183,22]	4	hSpCas9	negative selection	1756850
213005214	213005237	1	-	26627737	HCT116	viability after 6 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.7116584882736453	[692]	[73,235]	4	hSpCas9	negative selection	1756851
213008260	213008283	1	+	26627737	HCT116	viability after 6 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-1.577619233029082	[299]	[9,18]	-7	hSpCas9	negative selection	1756852
213008276	213008299	1	-	26627737	HCT116	viability after 6 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	1.1398997086265483	[226]	[106,62]	6	hSpCas9	negative selection	1756853
213013302	213013325	1	-	26627737	HCT116	viability after 6 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.5746002051776975	[174]	[78,19]	3	hSpCas9	negative selection	1756854
213015660	213015683	1	-	26627737	HCT116	viability after 6 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	1.6935282369503026	[289]	[189,123]	8	hSpCas9	negative selection	1756855
212997213	212997236	1	+	26627737	HCT116	viability after 8 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	1.536690177384782	[26]	[56,50,21]	9	hSpCas9	negative selection	1839165
213005214	213005237	1	-	26627737	HCT116	viability after 8 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.36839665201716426	[326]	[69,166,179]	-4	hSpCas9	negative selection	1839166
213008260	213008283	1	+	26627737	HCT116	viability after 8 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.7603329981827494	[62]	[76,62,36]	7	hSpCas9	negative selection	1839167
213008276	213008299	1	-	26627737	HCT116	viability after 8 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-1.0083522870042096	[349]	[106,99,80]	-8	hSpCas9	negative selection	1839168
213013302	213013325	1	-	26627737	HCT116	viability after 8 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.7681788099563217	[121]	[162,120,60]	7	hSpCas9	negative selection	1839169
213015660	213015683	1	-	26627737	HCT116	viability after 8 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	0.14504363567403256	[148]	[121,66,83]	1	hSpCas9	negative selection	1839170
212997213	212997236	1	+	26627737	HCT116	viability after 9 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-3.3687981960276048	[320]	[14,2]	-9	hSpCas9	negative selection	1921480
213005214	213005237	1	-	26627737	HCT116	viability after 9 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.6931423999908933	[692]	[133,98]	-5	hSpCas9	negative selection	1921481
213008260	213008283	1	+	26627737	HCT116	viability after 9 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.2689648352271212	[299]	[19,156]	2	hSpCas9	negative selection	1921482
213008276	213008299	1	-	26627737	HCT116	viability after 9 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	1.170865163596867	[226]	[131,139]	7	hSpCas9	negative selection	1921483
213013302	213013325	1	-	26627737	HCT116	viability after 9 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.0234974881790857	[174]	[99,5]	0	hSpCas9	negative selection	1921484
213015660	213015683	1	-	26627737	HCT116	viability after 9 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	0.8652771831598255	[289]	[25,231]	6	hSpCas9	negative selection	1921485
212997213	212997236	1	+	26627737	HCT116	viability after 12 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	1.9772997656672762	[26]	[28,56,83]	9	hSpCas9	negative selection	2003795
213005214	213005237	1	-	26627737	HCT116	viability after 12 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.1717967343902157	[326]	[75,218,170]	-2	hSpCas9	negative selection	2003796
213008260	213008283	1	+	26627737	HCT116	viability after 12 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-0.12940413992745858	[62]	[50,30,6]	-1	hSpCas9	negative selection	2003797
213008276	213008299	1	-	26627737	HCT116	viability after 12 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-1.243766342318661	[349]	[73,63,94]	-8	hSpCas9	negative selection	2003798
213013302	213013325	1	-	26627737	HCT116	viability after 12 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.576376597051012	[121]	[148,90,41]	5	hSpCas9	negative selection	2003799
213015660	213015683	1	-	26627737	HCT116	viability after 12 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-1.0145216254732143	[148]	[41,38,34]	-8	hSpCas9	negative selection	2003800
212997213	212997236	1	+	26627737	HCT116	viability after 15 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	2.0885954218008127	[26]	[48,97,48]	9	hSpCas9	negative selection	2086110
213005214	213005237	1	-	26627737	HCT116	viability after 15 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-1.0057306757361546	[326]	[112,80,88]	-7	hSpCas9	negative selection	2086111
213008260	213008283	1	+	26627737	HCT116	viability after 15 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-0.14257763048798955	[62]	[27,57,11]	-1	hSpCas9	negative selection	2086112
213008276	213008299	1	-	26627737	HCT116	viability after 15 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-1.7106142536861555	[349]	[49,83,48]	-9	hSpCas9	negative selection	2086113
213013302	213013325	1	-	26627737	HCT116	viability after 15 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.7719928914782996	[121]	[91,179,83]	6	hSpCas9	negative selection	2086114
213015660	213015683	1	-	26627737	HCT116	viability after 15 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	0.36461891774818	[148]	[224,50,68]	3	hSpCas9	negative selection	2086115
212997213	212997236	1	+	26627737	HCT116	viability after 18 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	2.7479375421338212	[26]	[55,143,57]	9	hSpCas9	negative selection	2168425
213005214	213005237	1	-	26627737	HCT116	viability after 18 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-1.0474263413366356	[326]	[20,68,142]	-7	hSpCas9	negative selection	2168426
213008260	213008283	1	+	26627737	HCT116	viability after 18 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-0.11425580174945571	[62]	[64,7,11]	-1	hSpCas9	negative selection	2168427
213008276	213008299	1	-	26627737	HCT116	viability after 18 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-1.5733846283775712	[349]	[58,77,30]	-8	hSpCas9	negative selection	2168428
213013302	213013325	1	-	26627737	HCT116	viability after 18 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.7550001632872769	[121]	[106,135,50]	6	hSpCas9	negative selection	2168429
213015660	213015683	1	-	26627737	HCT116	viability after 18 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-0.5266911277608013	[148]	[86,51,8]	-5	hSpCas9	negative selection	2168430
213008276	213008299	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.11088367157633827	[4,4]	[3,4]	2	hSpCas9	positive selection	2970236
213005353	213005376	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTCTTGTCAGTGAACCCAGTGG	ANGEL2	ENSG00000174606	0.2024004225156546	[4,4]	[3,5]	4	hSpCas9	positive selection	2970237
213013361	213013384	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	0.8359501955543452	[3,3]	[4,7]	9	hSpCas9	positive selection	2970238
213015615	213015638	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-0.04151081870410869	[3,3]	[2,2]	0	hSpCas9	positive selection	2970239
213008276	213008299	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.166854608765439	[4,4]	[3,2]	3	hSpCas9	positive selection	3038094
213005353	213005376	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTCTTGTCAGTGAACCCAGTGG	ANGEL2	ENSG00000174606	0.25637306899854984	[4,4]	[5,3]	4	hSpCas9	positive selection	3038095
213013361	213013384	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	0.08994920723822476	[3,3]	[3,2]	1	hSpCas9	positive selection	3038096
213015615	213015638	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.04994337284686096	[3,3]	[2,2]	0	hSpCas9	positive selection	3038097
213000345	213000368		-	24336571	A375	resistance to PLX after 7 days	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.27312465973156264	[3,5]	[3,3]	-7	hSpCas9	positive selection	3117136
213008253	213008276		+	24336571	A375	resistance to PLX after 7 days	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	-0.07569063137166965	[5,4]	[5,3]	-2	hSpCas9	positive selection	3117147
213008279	213008302		-	24336571	A375	resistance to PLX after 7 days	CTCACCTTTATAGACATTGCCGG	ANGEL2	ENSG00000174606	-0.11932273291907186	[8,8]	[7,8]	-4	hSpCas9	positive selection	3117159
213000321	213000344		+	24336571	A375	resistance to PLX after 7 days	CTCACTTTTCAGCTGTCACTAGG	ANGEL2	ENSG00000174606	-0.2589143140728271	[22,19]	[17,17]	-7	hSpCas9	positive selection	3117170
213008386	213008409		+	24336571	A375	resistance to PLX after 7 days	GATCAACATTTTTGTCTCCTAGG	ANGEL2	ENSG00000174606	0.17614754257444631	[29,28]	[32,33]	5	hSpCas9	positive selection	3117181
213000345	213000368		-	24336571	A375	resistance to PLX after 14 days	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.0459483767708464	[4,6]	[1,1]	0	hSpCas9	positive selection	3174929
213008253	213008276		+	24336571	A375	resistance to PLX after 14 days	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.6497970247465337	[5,4]	[2,4]	6	hSpCas9	positive selection	3174940
213008279	213008302		-	24336571	A375	resistance to PLX after 14 days	CTCACCTTTATAGACATTGCCGG	ANGEL2	ENSG00000174606	0.08024712645410964	[9,12]	[3,5]	0	hSpCas9	positive selection	3174952
213000321	213000344		+	24336571	A375	resistance to PLX after 14 days	CTCACTTTTCAGCTGTCACTAGG	ANGEL2	ENSG00000174606	-0.1432434208983644	[20,20]	[7,8]	-1	hSpCas9	positive selection	3174963
213008386	213008409		+	24336571	A375	resistance to PLX after 14 days	GATCAACATTTTTGTCTCCTAGG	ANGEL2	ENSG00000174606	1.2689505602672846	[29,17]	[24,27]	8	hSpCas9	positive selection	3174974
213000345	213000368		-	24336571	A375	viability after 7 days	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.5923645180552349	[7]	[3,5]	-7	hSpCas9	negative selection	3232722
213008253	213008276		+	24336571	A375	viability after 7 days	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.07914134068888368	[4]	[5,4]	1	hSpCas9	negative selection	3232733
213008279	213008302		-	24336571	A375	viability after 7 days	CTCACCTTTATAGACATTGCCGG	ANGEL2	ENSG00000174606	-0.6786957306448705	[15]	[8,8]	-7	hSpCas9	negative selection	3232745
213000321	213000344		+	24336571	A375	viability after 7 days	CTCACTTTTCAGCTGTCACTAGG	ANGEL2	ENSG00000174606	0.0320998933245743	[21]	[22,19]	0	hSpCas9	negative selection	3232756
213008386	213008409		+	24336571	A375	viability after 7 days	GATCAACATTTTTGTCTCCTAGG	ANGEL2	ENSG00000174606	-0.05890626579302882	[32]	[29,28]	-1	hSpCas9	negative selection	3232767
213000345	213000368		-	24336571	A375	viability after 14 days	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.40801334128719546	[7]	[4,6]	-5	hSpCas9	negative selection	3290515
213008253	213008276		+	24336571	A375	viability after 14 days	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.13809790866632032	[4]	[5,4]	1	hSpCas9	negative selection	3290526
213008279	213008302		-	24336571	A375	viability after 14 days	CTCACCTTTATAGACATTGCCGG	ANGEL2	ENSG00000174606	-0.3890194674036266	[15]	[9,12]	-4	hSpCas9	negative selection	3290538
213000321	213000344		+	24336571	A375	viability after 14 days	CTCACTTTTCAGCTGTCACTAGG	ANGEL2	ENSG00000174606	0.02514247390720359	[21]	[20,20]	0	hSpCas9	negative selection	3290549
213008386	213008409		+	24336571	A375	viability after 14 days	GATCAACATTTTTGTCTCCTAGG	ANGEL2	ENSG00000174606	-0.3560075403130669	[32]	[29,17]	-4	hSpCas9	negative selection	3290560
213013129	213013152	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	1.9206227638780746	[26,53]	[0,0]	7	hSpCas9	positive selection	3336526
213013186	213013209	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	1.7370477732577316	[29,61]	[0,0]	7	hSpCas9	positive selection	3336527
213008253	213008276	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	1.4104429252015935	[65,48]	[0,0]	6	hSpCas9	positive selection	3336528
213007125	213007148	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.7925223380047265	[264,264]	[0,0]	-5	hSpCas9	positive selection	3355776
213008311	213008334	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.6574133692587072	[96,96]	[0,0]	3	hSpCas9	positive selection	3355777
213007138	213007161	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.27148427444249457	[506,506]	[3,3]	1	hSpCas9	positive selection	3355778
213008276	213008299	1	-	26780180	HT29	viability (Avana library 4 designs)	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	1.93477535386065	[]	[]	7	hSpCas9	negative selection	3406342
213005353	213005376	1	-	26780180	HT29	viability (Avana library 4 designs)	ACTCTTGTCAGTGAACCCAGTGG	ANGEL2	ENSG00000174606	0.0634670089600968	[]	[]	0	hSpCas9	negative selection	3406343
213013361	213013384	1	-	26780180	HT29	viability (Avana library 4 designs)	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	2.17541316034417	[]	[]	7	hSpCas9	negative selection	3406344
213015614	213015637	1	+	26780180	HT29	viability (Avana library 4 designs)	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.37610006933015	[]	[]	1	hSpCas9	negative selection	3406345
213013361	213013384	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	4.69015260303528	[]	[]	7	hSpCas9	negative selection	3478840
213008276	213008299	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-1.4699395610953	[]	[]	-2	hSpCas9	negative selection	3478841
213005353	213005376	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTCTTGTCAGTGAACCCAGTGG	ANGEL2	ENSG00000174606	2.94698028878208	[]	[]	4	hSpCas9	negative selection	3478842
213015614	213015637	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-1.15116040271105	[]	[]	-1	hSpCas9	negative selection	3478843
213013092	213013115	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAAAACGAAGAAAACACCAAGG	ANGEL2	ENSG00000174606	-10.1678982347576	[]	[]	-7	hSpCas9	negative selection	3478844
213013128	213013151	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-2.14602658081505	[]	[]	-3	hSpCas9	negative selection	3478845
213013361	213013384	1	-	26780180	A375	viability (Avana lentiGuide)	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	3.97061507964495	[]	[]	4	hSpCas9	negative selection	3587499
213008276	213008299	1	-	26780180	A375	viability (Avana lentiGuide)	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	10.3684100444104	[]	[]	7	hSpCas9	negative selection	3587500
213005353	213005376	1	-	26780180	A375	viability (Avana lentiGuide)	ACTCTTGTCAGTGAACCCAGTGG	ANGEL2	ENSG00000174606	2.48673128834702	[]	[]	2	hSpCas9	negative selection	3587501
213015614	213015637	1	+	26780180	A375	viability (Avana lentiGuide)	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	2.02409547667881	[]	[]	2	hSpCas9	negative selection	3587502
213013092	213013115	1	-	26780180	A375	viability (Avana lentiGuide)	TCAAAACGAAGAAAACACCAAGG	ANGEL2	ENSG00000174606	-2.80015366842342	[]	[]	-5	hSpCas9	negative selection	3587503
213013128	213013151	1	-	26780180	A375	viability (Avana lentiGuide)	AGTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-0.669307251559756	[]	[]	-1	hSpCas9	negative selection	3587504
213013361	213013384	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	0.25891279855884375	[5]	[6,5]	7	hSpCas9	positive selection	3696158
213008276	213008299	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.10259291771082232	[6]	[5,5]	-2	hSpCas9	positive selection	3696159
213005353	213005376	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTCTTGTCAGTGAACCCAGTGG	ANGEL2	ENSG00000174606	0.09821693521737854	[6]	[6,5]	2	hSpCas9	positive selection	3696160
213015614	213015637	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-0.08468607961639643	[4]	[4,3]	-1	hSpCas9	positive selection	3696161
213013092	213013115	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAAAACGAAGAAAACACCAAGG	ANGEL2	ENSG00000174606	-0.7061173977736415	[4]	[2,2]	-7	hSpCas9	positive selection	3696162
213013128	213013151	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-0.29667909142265536	[4]	[4,2]	-4	hSpCas9	positive selection	3696163
213013361	213013384	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.04172213668834476	[5]	[2,5]	0	hSpCas9	positive selection	3804765
213008276	213008299	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.3238958546806004	[6]	[4,4]	-4	hSpCas9	positive selection	3804766
213005353	213005376	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTCTTGTCAGTGAACCCAGTGG	ANGEL2	ENSG00000174606	0.18777980740541833	[6]	[6,5]	4	hSpCas9	positive selection	3804767
213015614	213015637	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-0.22747581216643295	[5]	[2,4]	-3	hSpCas9	positive selection	3804768
213013092	213013115	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAAAACGAAGAAAACACCAAGG	ANGEL2	ENSG00000174606	0.11276876266245482	[4]	[5,3]	2	hSpCas9	positive selection	3804769
213013128	213013151	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-0.607625904562865	[4]	[2,2]	-6	hSpCas9	positive selection	3804770
213007138	213007161	1	-	26780180	A375	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	1.61163313190001	[]	[]	8	hSpCas9	negative selection	3913080
213013186	213013209	1	+	26780180	A375	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	1.55203181436136	[]	[]	8	hSpCas9	negative selection	3913081
213008253	213008276	1	+	26780180	A375	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.518222618790414	[]	[]	1	hSpCas9	negative selection	3913082
213007125	213007148	1	+	26780180	A375	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	0.887571793693383	[]	[]	4	hSpCas9	negative selection	3913083
213013129	213013152	1	-	26780180	A375	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	1.06730856542972	[]	[]	5	hSpCas9	negative selection	3913084
213008311	213008334	1	-	26780180	A375	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.824228636167739	[]	[]	3	hSpCas9	negative selection	3913085
213007138	213007161	1	-	26780180	HT29	viability (GeCKOv2 library)	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	1.31232374094814	[]	[]	6	hSpCas9	negative selection	4021046
213013186	213013209	1	+	26780180	HT29	viability (GeCKOv2 library)	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.440362748847781	[]	[]	1	hSpCas9	negative selection	4021047
213008253	213008276	1	+	26780180	HT29	viability (GeCKOv2 library)	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	1.57960249493566	[]	[]	8	hSpCas9	negative selection	4021048
213007125	213007148	1	+	26780180	HT29	viability (GeCKOv2 library)	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	0.891009450058986	[]	[]	4	hSpCas9	negative selection	4021049
213013129	213013152	1	-	26780180	HT29	viability (GeCKOv2 library)	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.38468450180123	[]	[]	1	hSpCas9	negative selection	4021050
213008311	213008334	1	-	26780180	HT29	viability (GeCKOv2 library)	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	1.25629344550264	[]	[]	6	hSpCas9	negative selection	4021051
213000345	213000368	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.3257867236582461	[2]	[0,0]	-7	hSpCas9	positive selection	4140385
213008253	213008276	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	1.42626883672173	[1]	[4,1]	9	hSpCas9	positive selection	4140396
213008279	213008302	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACCTTTATAGACATTGCCGG	ANGEL2	ENSG00000174606	0.624029411692775	[2]	[4,2]	9	hSpCas9	positive selection	4140408
213000321	213000344	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACTTTTCAGCTGTCACTAGG	ANGEL2	ENSG00000174606	0.11476206367164535	[3]	[2,3]	3	hSpCas9	positive selection	4140419
213008386	213008409	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATCAACATTTTTGTCTCCTAGG	ANGEL2	ENSG00000174606	0.18173882280077974	[5]	[3,4]	4	hSpCas9	positive selection	4140430
213000345	213000368	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.23849327917722096	[2]	[0,1,1,0]	2	hSpCas9	positive selection	4204407
213008253	213008276	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	-0.4064273175197471	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4204418
213008279	213008302	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACCTTTATAGACATTGCCGG	ANGEL2	ENSG00000174606	0.8716724642240834	[3]	[3,0,0,3]	6	hSpCas9	positive selection	4204430
213000321	213000344	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACTTTTCAGCTGTCACTAGG	ANGEL2	ENSG00000174606	-0.04659065563119352	[4]	[3,3,1,0]	0	hSpCas9	positive selection	4204441
213008386	213008409	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATCAACATTTTTGTCTCCTAGG	ANGEL2	ENSG00000174606	1.2483357340731793	[4]	[5,5,4,4]	9	hSpCas9	positive selection	4204452
213013129	213013152	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.07870506385874554	[1]	[1,0]	-1	hSpCas9	positive selection	4255601
213013186	213013209	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.4038773320684817	[1]	[1,2]	8	hSpCas9	positive selection	4255602
213008253	213008276	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	-0.052370244064995436	[2]	[2,0]	-1	hSpCas9	positive selection	4255603
213007125	213007148	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.28481273894972037	[3]	[3,0]	-5	hSpCas9	positive selection	4319883
213008311	213008334	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.14591456526965751	[2]	[2,1]	3	hSpCas9	positive selection	4319884
213007138	213007161	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.07763161596554985	[4]	[3,3]	1	hSpCas9	positive selection	4319885
213005424	213005446	1	-	27760321	OCIAML3	viability	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	-1.8532492931144386	[271,213]	[76,19]	-9	hSpCas9	negative selection	4377811
213008276	213008298	1	-	27760321	OCIAML3	viability	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.31003018594841925	[980,895]	[517,687]	-3	hSpCas9	negative selection	4377812
213008447	213008469	1	-	27760321	OCIAML3	viability	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	-0.6585168349115675	[221,186]	[93,109]	-6	hSpCas9	negative selection	4377813
213013128	213013150	1	-	27760321	OCIAML3	viability	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-1.4363088400062298	[362,362]	[96,115]	-8	hSpCas9	negative selection	4377814
213013360	213013382	1	-	27760321	OCIAML3	viability	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	0.15940833235360846	[538,415]	[298,563]	1	hSpCas9	negative selection	4377815
213005424	213005446	1	-	27760321	OCIAML2	viability	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	-0.7311564708783824	[271,213]	[105,132]	-6	hSpCas9	negative selection	4461274
213008276	213008298	1	-	27760321	OCIAML2	viability	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.546021580686739	[980,895]	[470,583]	-6	hSpCas9	negative selection	4461275
213008447	213008469	1	-	27760321	OCIAML2	viability	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	-0.41335064710929936	[221,186]	[96,158]	-5	hSpCas9	negative selection	4461276
213013128	213013150	1	-	27760321	OCIAML2	viability	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-1.1129073229042354	[362,362]	[124,150]	-8	hSpCas9	negative selection	4461277
213013360	213013382	1	-	27760321	OCIAML2	viability	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	-0.1833982913167455	[538,415]	[278,414]	-2	hSpCas9	negative selection	4461278
213005424	213005446	1	-	27760321	MV411	viability	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	-1.027639511722954	[271,213]	[10,178]	-6	hSpCas9	negative selection	4544737
213008276	213008298	1	-	27760321	MV411	viability	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	1.4557665734215173	[980,895]	[2498,494]	9	hSpCas9	negative selection	4544738
213008447	213008469	1	-	27760321	MV411	viability	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	1.6921615036725377	[221,186]	[489,350]	9	hSpCas9	negative selection	4544739
213013128	213013150	1	-	27760321	MV411	viability	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	0.7801703616087505	[362,362]	[566,180]	6	hSpCas9	negative selection	4544740
213013360	213013382	1	-	27760321	MV411	viability	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	1.0643219114923002	[538,415]	[817,407]	7	hSpCas9	negative selection	4544741
213005424	213005446	1	-	27760321	HL60	viability	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	0.2116135157933544	[271,213]	[140,320]	2	hSpCas9	negative selection	4628200
213008276	213008298	1	-	27760321	HL60	viability	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.3315170132515699	[980,895]	[790,1147]	4	hSpCas9	negative selection	4628201
213008447	213008469	1	-	27760321	HL60	viability	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	0.8950242874728831	[221,186]	[358,256]	8	hSpCas9	negative selection	4628202
213013128	213013150	1	-	27760321	HL60	viability	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-0.6683688172637199	[362,362]	[176,197]	-6	hSpCas9	negative selection	4628203
213013360	213013382	1	-	27760321	HL60	viability	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	0.3767353590927445	[538,415]	[643,352]	4	hSpCas9	negative selection	4628204
213005424	213005446	1	-	27760321	HT1080	viability	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	1.638483628386597	[213,166]	[241,229]	8	hSpCas9	negative selection	4711663
213008276	213008298	1	-	27760321	HT1080	viability	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	1.581921308337639	[895,698]	[1078,810]	8	hSpCas9	negative selection	4711664
213008447	213008469	1	-	27760321	HT1080	viability	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	0.8883845078925673	[186,145]	[54,196]	5	hSpCas9	negative selection	4711665
213013128	213013150	1	-	27760321	HT1080	viability	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	0.21290645232210065	[362,282]	[214,76]	1	hSpCas9	negative selection	4711666
213013360	213013382	1	-	27760321	HT1080	viability	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	1.0206333321077956	[415,324]	[382,207]	5	hSpCas9	negative selection	4711667
213005424	213005446	1	-	27760321	HT29	viability after 7 days	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	-0.1868066636498943	[213,166]	[187,226,225]	-3	hSpCas9	negative selection	4795126
213008276	213008298	1	-	27760321	HT29	viability after 7 days	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.3229936100488533	[895,698]	[758,897,792]	-4	hSpCas9	negative selection	4795127
213008447	213008469	1	-	27760321	HT29	viability after 7 days	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	-0.07867164810042637	[186,145]	[147,215,234]	-1	hSpCas9	negative selection	4795128
213013128	213013150	1	-	27760321	HT29	viability after 7 days	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-0.6894231912394858	[362,282]	[272,232,267]	-7	hSpCas9	negative selection	4795129
213013360	213013382	1	-	27760321	HT29	viability after 7 days	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	0.1360104885330819	[415,324]	[348,582,609]	2	hSpCas9	negative selection	4795130
213005424	213005446	1	-	27760321	HT29	viability after 25 days	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	-0.3123136866872013	[213,166]	[246,160,105]	-3	hSpCas9	negative selection	4878589
213008276	213008298	1	-	27760321	HT29	viability after 25 days	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.12291155706889101	[895,698]	[733,712,1095]	-1	hSpCas9	negative selection	4878590
213008447	213008469	1	-	27760321	HT29	viability after 25 days	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	-0.5370163409539337	[186,145]	[106,119,171]	-5	hSpCas9	negative selection	4878591
213013128	213013150	1	-	27760321	HT29	viability after 25 days	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	0.30658967565424805	[362,282]	[552,531,256]	3	hSpCas9	negative selection	4878592
213013360	213013382	1	-	27760321	HT29	viability after 25 days	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	0.16929020709070347	[415,324]	[496,439,490]	1	hSpCas9	negative selection	4878593
213005424	213005446	1	-	27760321	HT29	viability after 22 days	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	-0.0416471322290235	[213,166]	[212,203,224]	0	hSpCas9	negative selection	4962052
213008276	213008298	1	-	27760321	HT29	viability after 22 days	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.2646577983087084	[895,698]	[683,1003,614]	-3	hSpCas9	negative selection	4962053
213008447	213008469	1	-	27760321	HT29	viability after 22 days	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	-0.47912367692189717	[186,145]	[91,134,188]	-4	hSpCas9	negative selection	4962054
213013128	213013150	1	-	27760321	HT29	viability after 22 days	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-0.10107074349305109	[362,282]	[451,400,186]	-1	hSpCas9	negative selection	4962055
213013360	213013382	1	-	27760321	HT29	viability after 22 days	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	0.23543017045242903	[415,324]	[282,602,633]	2	hSpCas9	negative selection	4962056
213005424	213005446	1	-	27760321	HT29	viability after 19 days	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	-0.14899819054876817	[213,166]	[202,189,196]	-1	hSpCas9	negative selection	5045515
213008276	213008298	1	-	27760321	HT29	viability after 19 days	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.04238059369115188	[895,698]	[1136,1007,701]	0	hSpCas9	negative selection	5045516
213008447	213008469	1	-	27760321	HT29	viability after 19 days	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	0.10342601179328192	[186,145]	[127,176,296]	0	hSpCas9	negative selection	5045517
213013128	213013150	1	-	27760321	HT29	viability after 19 days	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-0.48263243939439004	[362,282]	[383,279,145]	-4	hSpCas9	negative selection	5045518
213013360	213013382	1	-	27760321	HT29	viability after 19 days	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	0.26115236401400554	[415,324]	[490,644,389]	2	hSpCas9	negative selection	5045519
213005424	213005446	1	-	27760321	HT29	viability after 16 days	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	0.5008706741908509	[213,166]	[416,325,171]	6	hSpCas9	negative selection	5128978
213008276	213008298	1	-	27760321	HT29	viability after 16 days	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.02849947044166079	[895,698]	[876,825,1025]	0	hSpCas9	negative selection	5128979
213008447	213008469	1	-	27760321	HT29	viability after 16 days	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	-0.7627431985583382	[186,145]	[145,62,124]	-6	hSpCas9	negative selection	5128980
213013128	213013150	1	-	27760321	HT29	viability after 16 days	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-0.5176833376942193	[362,282]	[341,237,185]	-5	hSpCas9	negative selection	5128981
213013360	213013382	1	-	27760321	HT29	viability after 16 days	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	0.9109385498092942	[415,324]	[450,1399,439]	9	hSpCas9	negative selection	5128982
213005424	213005446	1	-	27760321	HT29	viability after 13 days	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	-0.15441367699822506	[213,166]	[122,276,195]	-2	hSpCas9	negative selection	5212441
213008276	213008298	1	-	27760321	HT29	viability after 13 days	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.3296704477608302	[895,698]	[526,862,813]	-4	hSpCas9	negative selection	5212442
213008447	213008469	1	-	27760321	HT29	viability after 13 days	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	-0.29700382469727926	[186,145]	[96,84,281]	-4	hSpCas9	negative selection	5212443
213013128	213013150	1	-	27760321	HT29	viability after 13 days	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-0.2685039841697662	[362,282]	[380,377,181]	-3	hSpCas9	negative selection	5212444
213013360	213013382	1	-	27760321	HT29	viability after 13 days	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	0.5374592261942599	[415,324]	[703,724,452]	7	hSpCas9	negative selection	5212445
213005424	213005446	1	-	27760321	HT29	viability after 10 days	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	0.22697869028190876	[213,166]	[311,321,203]	3	hSpCas9	negative selection	5295904
213008276	213008298	1	-	27760321	HT29	viability after 10 days	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.13800365858410824	[895,698]	[863,813,1030]	-2	hSpCas9	negative selection	5295905
213008447	213008469	1	-	27760321	HT29	viability after 10 days	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	-0.5042753760511169	[186,145]	[72,145,218]	-6	hSpCas9	negative selection	5295906
213013128	213013150	1	-	27760321	HT29	viability after 10 days	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	0.11897424188420753	[362,282]	[623,420,271]	1	hSpCas9	negative selection	5295907
213013360	213013382	1	-	27760321	HT29	viability after 10 days	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	0.09430176996859539	[415,324]	[428,311,729]	1	hSpCas9	negative selection	5295908
213005424	213005446	1	-	27760321	MOLM13	viability	GTGAATATAAGATGCGGACAGG	ANGEL2	ENSG00000174606	-0.1573236185581064	[271,213]	[5,220]	-1	hSpCas9	negative selection	5379367
213008276	213008298	1	-	27760321	MOLM13	viability	CCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.30914757502003853	[980,895]	[759,566]	2	hSpCas9	negative selection	5379368
213008447	213008469	1	-	27760321	MOLM13	viability	AGGTGTGATAAAGCGGAATTGG	ANGEL2	ENSG00000174606	-0.24896970993570533	[221,186]	[207,1]	-2	hSpCas9	negative selection	5379369
213013128	213013150	1	-	27760321	MOLM13	viability	GTTACGTCATGAACGCTGAGGG	ANGEL2	ENSG00000174606	-2.8635133821543426	[362,362]	[51,7]	-8	hSpCas9	negative selection	5379370
213013360	213013382	1	-	27760321	MOLM13	viability	AGAGACTGGACTACACCGTGGG	ANGEL2	ENSG00000174606	-0.8437634370261737	[538,415]	[168,131]	-5	hSpCas9	negative selection	5379371
213014986	213015009	1	+	27661255	K562	viability	GCTTAGGGTGAAGCTAATGTGGG	ANGEL2	ENSG00000174606	0.09139290753523592	[753,860]	[758,622]	3	dCas9-KRAB	negative selection	5462120
213015328	213015351	1	+	27661255	K562	viability	GGCCAGGGATCCAAAGCCACTGG	ANGEL2	ENSG00000174606	-0.02256118596577239	[1553,1818]	[1308,1333]	-1	dCas9-KRAB	negative selection	5462121
213015383	213015406	1	+	27661255	K562	viability	GCCAAGACCCCAGACCTCGTTGG	ANGEL2	ENSG00000174606	0.16489208655636445	[1174,1496]	[1255,1135]	6	dCas9-KRAB	negative selection	5462122
213015735	213015758	1	+	27661255	K562	viability	GCGACGGCCTAAAGTATCTAGGG	ANGEL2	ENSG00000174606	-0.08124078891988995	[475,459]	[365,342]	-3	dCas9-KRAB	negative selection	5462123
213015167	213015190	1	-	27661255	K562	viability	GTGTGGCACACGCCCAGGAGGGG	ANGEL2	ENSG00000174606	-0.0657047633057839	[1629,1742]	[1364,1217]	-3	dCas9-KRAB	negative selection	5462124
213015369	213015392	1	-	27661255	K562	viability	GGTCTTGGCGCGGAGTTCATGGG	ANGEL2	ENSG00000174606	0.039143800581938226	[1508,1453]	[1300,1144]	1	dCas9-KRAB	negative selection	5462125
213015467	213015490	1	-	27661255	K562	viability	GTCTGGGCGATGGTGCATCCGGG	ANGEL2	ENSG00000174606	-0.14594205118328724	[896,925]	[776,555]	-5	dCas9-KRAB	negative selection	5462126
213013129	213013152	1	-	27260156	BXPC3	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.14715012034143582	[153]	[142,139,229,209]	3	hSpCas9	negative selection	5528061
213013186	213013209	1	+	27260156	BXPC3	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.041155651244202174	[193]	[224,218,221,158]	0	hSpCas9	negative selection	5528062
213008253	213008276	1	+	27260156	BXPC3	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.5415604605738075	[319]	[433,533,439,545]	9	hSpCas9	negative selection	5528063
213007125	213007148	1	+	27260156	BXPC3	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.10168006847158534	[666]	[584,453,822,769]	-2	hSpCas9	negative selection	5592343
213008311	213008334	1	-	27260156	BXPC3	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.3867814920764213	[235]	[346,222,357,369]	8	hSpCas9	negative selection	5592344
213007138	213007161	1	-	27260156	BXPC3	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.002468631776803676	[1190]	[1153,1208,1209,1443]	0	hSpCas9	negative selection	5592345
213013129	213013152	1	-	27260156	A673	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.06036163100891501	[153]	[204,132,291,139]	1	hSpCas9	negative selection	5649312
213013186	213013209	1	+	27260156	A673	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.09795928047767322	[193]	[323,151,181,226]	-2	hSpCas9	negative selection	5649313
213008253	213008276	1	+	27260156	A673	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.3366193865795092	[319]	[546,442,475,481]	7	hSpCas9	negative selection	5649314
213007125	213007148	1	+	27260156	A673	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.10878523304262533	[666]	[703,702,775,784]	-3	hSpCas9	negative selection	5713594
213008311	213008334	1	-	27260156	A673	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.17241443447528693	[235]	[529,249,246,273]	4	hSpCas9	negative selection	5713595
213007138	213007161	1	-	27260156	A673	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.09449011423883502	[1190]	[1371,1230,1590,1154]	-2	hSpCas9	negative selection	5713596
213013129	213013152	1	-	27260156	A375	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.02970532551157712	[153]	[200,175,129,194]	0	hSpCas9	negative selection	5770563
213013186	213013209	1	+	27260156	A375	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.45440479246566556	[193]	[85,287,282,35]	-6	hSpCas9	negative selection	5770564
213008253	213008276	1	+	27260156	A375	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.5308660414614655	[319]	[440,709,546,488]	7	hSpCas9	negative selection	5770565
213007125	213007148	1	+	27260156	A375	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.1718909047613642	[666]	[526,650,834,737]	-2	hSpCas9	negative selection	5834845
213008311	213008334	1	-	27260156	A375	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.3915253754168464	[235]	[304,559,299,312]	6	hSpCas9	negative selection	5834846
213007138	213007161	1	-	27260156	A375	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.17015900658076966	[1190]	[1314,1683,1042,990]	-2	hSpCas9	negative selection	5834847
213013129	213013152	1	-	27260156	COLO741	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.3550175214455158	[153]	[195,220,326]	7	hSpCas9	negative selection	5891814
213013186	213013209	1	+	27260156	COLO741	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.0184053117732772	[193]	[268,170,291]	0	hSpCas9	negative selection	5891815
213008253	213008276	1	+	27260156	COLO741	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.33198293720594596	[319]	[565,576,411]	7	hSpCas9	negative selection	5891816
213007125	213007148	1	+	27260156	COLO741	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.053074353417164155	[666]	[1078,822,598]	-1	hSpCas9	negative selection	5956096
213008311	213008334	1	-	27260156	COLO741	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.12210787187782757	[235]	[379,278,328]	2	hSpCas9	negative selection	5956097
213007138	213007161	1	-	27260156	COLO741	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.09076893444537792	[1190]	[1940,1164,1234]	-2	hSpCas9	negative selection	5956098
213013129	213013152	1	-	27260156	CAL120	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.4662984404646535	[153]	[93,159,509]	7	hSpCas9	negative selection	6013065
213013186	213013209	1	+	27260156	CAL120	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.15084014992412742	[193]	[134,272,373]	2	hSpCas9	negative selection	6013066
213008253	213008276	1	+	27260156	CAL120	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.29238043678689835	[319]	[364,572,505]	4	hSpCas9	negative selection	6013067
213007125	213007148	1	+	27260156	CAL120	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.005347278351070128	[666]	[898,915,678]	0	hSpCas9	negative selection	6077347
213008311	213008334	1	-	27260156	CAL120	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.9250988124586509	[235]	[1080,368,305]	9	hSpCas9	negative selection	6077348
213007138	213007161	1	-	27260156	CAL120	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.07741053613336502	[1190]	[1655,1293,1302]	-1	hSpCas9	negative selection	6077349
213013129	213013152	1	-	27260156	CADOES1	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.5550734959371566	[153]	[59,151,109,66]	-7	hSpCas9	negative selection	6134316
213013186	213013209	1	+	27260156	CADOES1	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.6186864575265048	[193]	[96,139,118,113]	-8	hSpCas9	negative selection	6134317
213008253	213008276	1	+	27260156	CADOES1	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.249021606305234	[319]	[275,331,373,435]	4	hSpCas9	negative selection	6134318
213007125	213007148	1	+	27260156	CADOES1	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.14384288570188342	[666]	[612,670,401,559]	-2	hSpCas9	negative selection	6198598
213008311	213008334	1	-	27260156	CADOES1	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.4012089577124077	[235]	[272,354,232,298]	6	hSpCas9	negative selection	6198599
213007138	213007161	1	-	27260156	CADOES1	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.09252546332620026	[1190]	[957,1141,1041,1012]	-1	hSpCas9	negative selection	6198600
213013129	213013152	1	-	27260156	EWS502	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.023970336307167273	[153]	[148,164,141,187]	0	hSpCas9	negative selection	6255567
213013186	213013209	1	+	27260156	EWS502	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.2396984907363171	[193]	[81,182,212,232]	-4	hSpCas9	negative selection	6255568
213008253	213008276	1	+	27260156	EWS502	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.36813793458703514	[319]	[463,337,397,556]	6	hSpCas9	negative selection	6255569
213007125	213007148	1	+	27260156	EWS502	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.06571173393668583	[666]	[489,810,726,687]	-1	hSpCas9	negative selection	6319849
213008311	213008334	1	-	27260156	EWS502	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.08326281216981835	[235]	[284,200,291,281]	1	hSpCas9	negative selection	6319850
213007138	213007161	1	-	27260156	EWS502	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.052737596746996296	[1190]	[916,1258,1436,1289]	-1	hSpCas9	negative selection	6319851
213013129	213013152	1	-	27260156	EW8	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.19301909182621535	[153]	[198,123,46,86]	-4	hSpCas9	negative selection	6376818
213013186	213013209	1	+	27260156	EW8	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.34782921677225187	[193]	[123,131,146,86]	-6	hSpCas9	negative selection	6376819
213008253	213008276	1	+	27260156	EW8	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.44067552830505996	[319]	[370,305,259,486]	7	hSpCas9	negative selection	6376820
213007125	213007148	1	+	27260156	EW8	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.2529210352211858	[666]	[460,417,493,433]	-5	hSpCas9	negative selection	6441100
213008311	213008334	1	-	27260156	EW8	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.19377281121433299	[235]	[163,307,187,213]	3	hSpCas9	negative selection	6441101
213007138	213007161	1	-	27260156	EW8	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.10371214086302949	[1190]	[1130,1208,853,993]	2	hSpCas9	negative selection	6441102
213013129	213013152	1	-	27260156	CORL105	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.25420634506929507	[153]	[210,158,272,226]	5	hSpCas9	negative selection	6498069
213013186	213013209	1	+	27260156	CORL105	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.06574565258779042	[193]	[237,269,254,189]	1	hSpCas9	negative selection	6498070
213008253	213008276	1	+	27260156	CORL105	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.2819231299125343	[319]	[424,489,567,354]	5	hSpCas9	negative selection	6498071
213007125	213007148	1	+	27260156	CORL105	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.19466378396277795	[666]	[774,532,764,674]	-4	hSpCas9	negative selection	6562351
213008311	213008334	1	-	27260156	CORL105	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.28247131255340485	[235]	[326,277,519,248]	5	hSpCas9	negative selection	6562352
213007138	213007161	1	-	27260156	CORL105	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.30873744595622576	[1190]	[1199,1049,1304,979]	-5	hSpCas9	negative selection	6562353
213013129	213013152	1	-	27260156	HS294T	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.5335130744508527	[153]	[178,67,37,43]	7	hSpCas9	negative selection	6619320
213013186	213013209	1	+	27260156	HS294T	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.3550521639705513	[193]	[38,44,62,95]	-5	hSpCas9	negative selection	6619321
213008253	213008276	1	+	27260156	HS294T	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.2182863117049384	[319]	[107,190,139,136]	3	hSpCas9	negative selection	6619322
213007125	213007148	1	+	27260156	HS294T	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.7440658175203152	[666]	[127,122,168,207]	-8	hSpCas9	negative selection	6683602
213008311	213008334	1	-	27260156	HS294T	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.1414368200821	[235]	[117,79,113,86]	2	hSpCas9	negative selection	6683603
213007138	213007161	1	-	27260156	HS294T	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.03374291261678741	[1190]	[307,641,452,494]	0	hSpCas9	negative selection	6683604
213013129	213013152	1	-	27260156	HCC44	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.5106342262244876	[153]	[472,211,149,166]	8	hSpCas9	negative selection	6740571
213013186	213013209	1	+	27260156	HCC44	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.35280883351412773	[193]	[219,49,193,244]	-5	hSpCas9	negative selection	6740572
213008253	213008276	1	+	27260156	HCC44	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.31636849645552817	[319]	[345,316,718,471]	5	hSpCas9	negative selection	6740573
213007125	213007148	1	+	27260156	HCC44	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.1992025174550568	[666]	[748,599,956,393]	-3	hSpCas9	negative selection	6804853
213008311	213008334	1	-	27260156	HCC44	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.7543425936184086	[235]	[466,527,353,422]	9	hSpCas9	negative selection	6804854
213007138	213007161	1	-	27260156	HCC44	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.20012003894422992	[1190]	[1133,788,1439,1406]	-3	hSpCas9	negative selection	6804855
213013129	213013152	1	-	27260156	G402	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.5650155596053685	[153]	[510,151,148,322]	7	hSpCas9	negative selection	6861822
213013186	213013209	1	+	27260156	G402	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.43549605915719214	[193]	[321,250,122,35]	-5	hSpCas9	negative selection	6861823
213008253	213008276	1	+	27260156	G402	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.4875487005581098	[319]	[910,553,321,457]	6	hSpCas9	negative selection	6861824
213007125	213007148	1	+	27260156	G402	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.18912471139323422	[666]	[966,955,512,478]	-2	hSpCas9	negative selection	6926104
213008311	213008334	1	-	27260156	G402	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.23768021210880275	[235]	[329,281,397,341]	3	hSpCas9	negative selection	6926105
213007138	213007161	1	-	27260156	G402	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.05154019354097561	[1190]	[1729,1642,1251,1056]	0	hSpCas9	negative selection	6926106
213013129	213013152	1	-	27260156	L33	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.04342774417920725	[153]	[157,66,66,168]	-1	hSpCas9	negative selection	6983073
213013186	213013209	1	+	27260156	L33	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.2300485053487833	[193]	[238,60,205,194]	5	hSpCas9	negative selection	6983074
213008253	213008276	1	+	27260156	L33	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.34116100599446253	[319]	[515,173,204,351]	7	hSpCas9	negative selection	6983075
213007125	213007148	1	+	27260156	L33	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	0.2512687114213388	[666]	[872,318,450,803]	5	hSpCas9	negative selection	7047355
213008311	213008334	1	-	27260156	L33	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	-0.3787426718935747	[235]	[202,76,105,165]	-7	hSpCas9	negative selection	7047356
213007138	213007161	1	-	27260156	L33	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.15104880343978278	[1190]	[978,468,767,948]	-3	hSpCas9	negative selection	7047357
213013129	213013152	1	-	27260156	K562	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.5167707923340707	[153]	[93,414,244,47]	6	hSpCas9	negative selection	7104324
213013186	213013209	1	+	27260156	K562	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.6098370760515963	[193]	[78,161,62,142]	-6	hSpCas9	negative selection	7104325
213008253	213008276	1	+	27260156	K562	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.7571281880737118	[319]	[588,698,290,371]	8	hSpCas9	negative selection	7104326
213007125	213007148	1	+	27260156	K562	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.21923934609636492	[666]	[538,440,554,496]	-3	hSpCas9	negative selection	7168606
213008311	213008334	1	-	27260156	K562	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.501863455373704	[235]	[323,209,288,352]	6	hSpCas9	negative selection	7168607
213007138	213007161	1	-	27260156	K562	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.05993531004707431	[1190]	[1483,1040,893,1020]	0	hSpCas9	negative selection	7168608
213013129	213013152	1	-	27260156	HT29	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.23634096676507554	[153]	[300,94,313,171]	4	hSpCas9	negative selection	7225575
213013186	213013209	1	+	27260156	HT29	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.13133211023006086	[193]	[253,215,223,324]	2	hSpCas9	negative selection	7225576
213008253	213008276	1	+	27260156	HT29	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.22677637271851758	[319]	[530,465,297,520]	4	hSpCas9	negative selection	7225577
213007125	213007148	1	+	27260156	HT29	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.028397496088772234	[666]	[688,877,916,700]	0	hSpCas9	negative selection	7289857
213008311	213008334	1	-	27260156	HT29	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.019354606634995664	[235]	[350,178,227,385]	0	hSpCas9	negative selection	7289858
213007138	213007161	1	-	27260156	HT29	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.059494988733032717	[1190]	[1531,1619,1405,1060]	-1	hSpCas9	negative selection	7289859
213013129	213013152	1	-	27260156	MHHES1	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.10753724050524127	[153]	[226,123,206,100]	-2	hSpCas9	negative selection	7346826
213013186	213013209	1	+	27260156	MHHES1	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.2079580652955786	[193]	[389,240,269,143]	4	hSpCas9	negative selection	7346827
213008253	213008276	1	+	27260156	MHHES1	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.35679720182281355	[319]	[599,549,416,325]	6	hSpCas9	negative selection	7346828
213007125	213007148	1	+	27260156	MHHES1	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.3916478756452014	[666]	[595,530,617,538]	-6	hSpCas9	negative selection	7411108
213008311	213008334	1	-	27260156	MHHES1	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	-0.21452894445862603	[235]	[282,309,219,134]	-4	hSpCas9	negative selection	7411109
213007138	213007161	1	-	27260156	MHHES1	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.33794891071800737	[1190]	[1367,1350,851,780]	-6	hSpCas9	negative selection	7411110
213013129	213013152	1	-	27260156	MEWO	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.06172293180455335	[153]	[226,136,101]	1	hSpCas9	negative selection	7468077
213013186	213013209	1	+	27260156	MEWO	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.012526092223507534	[193]	[174,108,263]	0	hSpCas9	negative selection	7468078
213008253	213008276	1	+	27260156	MEWO	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.19939925005204917	[319]	[461,362,228]	4	hSpCas9	negative selection	7468079
213007125	213007148	1	+	27260156	MEWO	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	0.21471265139873952	[666]	[751,868,555]	5	hSpCas9	negative selection	7532359
213008311	213008334	1	-	27260156	MEWO	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	-0.4672277119798198	[235]	[209,126,151]	-7	hSpCas9	negative selection	7532360
213007138	213007161	1	-	27260156	MEWO	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.020914867345984467	[1190]	[1235,1080,1094]	0	hSpCas9	negative selection	7532361
213013129	213013152	1	-	27260156	LNCAPCLONEFGC	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.012409934049416371	[153]	[150,191,159,58]	0	hSpCas9	negative selection	7589328
213013186	213013209	1	+	27260156	LNCAPCLONEFGC	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.2679499485453338	[193]	[160,113,128,178]	-4	hSpCas9	negative selection	7589329
213008253	213008276	1	+	27260156	LNCAPCLONEFGC	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.15037856068064492	[319]	[368,241,415,277]	2	hSpCas9	negative selection	7589330
213007125	213007148	1	+	27260156	LNCAPCLONEFGC	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.321339074547778	[666]	[546,361,599,448]	-5	hSpCas9	negative selection	7653610
213008311	213008334	1	-	27260156	LNCAPCLONEFGC	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.22460968074664267	[235]	[315,213,201,260]	3	hSpCas9	negative selection	7653611
213007138	213007161	1	-	27260156	LNCAPCLONEFGC	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.25277741229459094	[1190]	[809,868,1049,917]	-4	hSpCas9	negative selection	7653612
213013129	213013152	1	-	27260156	PANC0327	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.24513278907163727	[153]	[217,30,129,101]	-4	hSpCas9	negative selection	7710579
213013186	213013209	1	+	27260156	PANC0327	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	1.002056725166573	[193]	[911,179,116,238]	9	hSpCas9	negative selection	7710580
213008253	213008276	1	+	27260156	PANC0327	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.03418111344392727	[319]	[295,303,309,252]	0	hSpCas9	negative selection	7710581
213007125	213007148	1	+	27260156	PANC0327	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.19768001960245418	[666]	[534,577,509,436]	-3	hSpCas9	negative selection	7774861
213008311	213008334	1	-	27260156	PANC0327	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	-0.001418089267266609	[235]	[343,167,162,178]	0	hSpCas9	negative selection	7774862
213007138	213007161	1	-	27260156	PANC0327	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.030681314595226716	[1190]	[1402,1017,970,782]	0	hSpCas9	negative selection	7774863
213013129	213013152	1	-	27260156	NCIH2009	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.14407186741327327	[153]	[120,262,183]	-2	hSpCas9	negative selection	7831830
213013186	213013209	1	+	27260156	NCIH2009	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.5318883196880921	[193]	[497,224,475]	7	hSpCas9	negative selection	7831831
213008253	213008276	1	+	27260156	NCIH2009	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.19609805090197113	[319]	[765,448,371]	2	hSpCas9	negative selection	7831832
213007125	213007148	1	+	27260156	NCIH2009	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	0.007380211676776605	[666]	[1226,927,710]	0	hSpCas9	negative selection	7896112
213008311	213008334	1	-	27260156	NCIH2009	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	-0.19250889859664877	[235]	[247,294,313]	-3	hSpCas9	negative selection	7896113
213007138	213007161	1	-	27260156	NCIH2009	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.221875286568868	[1190]	[1820,1201,1336]	-3	hSpCas9	negative selection	7896114
213013129	213013152	1	-	27260156	NCIH1373	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.07606594138026823	[153]	[65,130,348,42]	0	hSpCas9	negative selection	7953081
213013186	213013209	1	+	27260156	NCIH1373	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.48786222024556913	[193]	[347,178,348,95]	5	hSpCas9	negative selection	7953082
213008253	213008276	1	+	27260156	NCIH1373	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.8414986880119653	[319]	[1003,504,699,108]	8	hSpCas9	negative selection	7953083
213007125	213007148	1	+	27260156	NCIH1373	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.5005714736817491	[666]	[754,468,405,137]	-5	hSpCas9	negative selection	8017363
213008311	213008334	1	-	27260156	NCIH1373	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.7867761631961805	[235]	[772,286,410,109]	7	hSpCas9	negative selection	8017364
213007138	213007161	1	-	27260156	NCIH1373	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.048598917480740855	[1190]	[1746,892,1594,265]	0	hSpCas9	negative selection	8017365
213013129	213013152	1	-	27260156	PATU8902	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.09783591089762589	[153]	[202,206,145,402]	1	hSpCas9	negative selection	8074332
213013186	213013209	1	+	27260156	PATU8902	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.9034812407884603	[193]	[144,70,132,241]	-7	hSpCas9	negative selection	8074333
213008253	213008276	1	+	27260156	PATU8902	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.48704778714729363	[319]	[478,608,563,890]	5	hSpCas9	negative selection	8074334
213007125	213007148	1	+	27260156	PATU8902	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.38762399212309123	[666]	[598,756,617,909]	-4	hSpCas9	negative selection	8138614
213008311	213008334	1	-	27260156	PATU8902	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.2882275976563461	[235]	[296,802,218,323]	3	hSpCas9	negative selection	8138615
213007138	213007161	1	-	27260156	PATU8902	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.09779883912854048	[1190]	[1542,1284,1602,2826]	1	hSpCas9	negative selection	8138616
213013129	213013152	1	-	27260156	PANC1	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.27497326352487494	[153]	[168,184,146,143]	4	hSpCas9	negative selection	8195583
213013186	213013209	1	+	27260156	PANC1	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.3616422512025381	[193]	[240,232,248,144]	6	hSpCas9	negative selection	8195584
213008253	213008276	1	+	27260156	PANC1	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.4132609886556009	[319]	[343,499,260,377]	6	hSpCas9	negative selection	8195585
213007125	213007148	1	+	27260156	PANC1	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	0.19389502334853814	[666]	[761,673,667,528]	3	hSpCas9	negative selection	8259865
213008311	213008334	1	-	27260156	PANC1	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.4635863907531744	[235]	[326,234,201,329]	7	hSpCas9	negative selection	8259866
213007138	213007161	1	-	27260156	PANC1	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.09131136673901574	[1190]	[905,1309,1235,960]	1	hSpCas9	negative selection	8259867
213013129	213013152	1	-	27260156	PANC0813	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.15383715196352354	[153]	[127,307,80,275]	2	hSpCas9	negative selection	8316834
213013186	213013209	1	+	27260156	PANC0813	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.12179285327789557	[193]	[206,207,341,231]	2	hSpCas9	negative selection	8316835
213008253	213008276	1	+	27260156	PANC0813	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.5249966992393482	[319]	[670,556,525,426]	8	hSpCas9	negative selection	8316836
213007125	213007148	1	+	27260156	PANC0813	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.038607976686577894	[666]	[740,957,637,712]	0	hSpCas9	negative selection	8381116
213008311	213008334	1	-	27260156	PANC0813	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	-0.09254366293536864	[235]	[291,200,260,286]	-1	hSpCas9	negative selection	8381117
213007138	213007161	1	-	27260156	PANC0813	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.0018322229937828283	[1190]	[1671,1286,1334,1321]	0	hSpCas9	negative selection	8381118
213013129	213013152	1	-	27260156	RDES	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.020594220892367954	[153]	[165,174,112,273]	0	hSpCas9	negative selection	8438085
213013186	213013209	1	+	27260156	RDES	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.027505120382760317	[193]	[223,224,176,241]	0	hSpCas9	negative selection	8438086
213008253	213008276	1	+	27260156	RDES	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.33777772609386963	[319]	[333,508,475,567]	5	hSpCas9	negative selection	8438087
213007125	213007148	1	+	27260156	RDES	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.2083712445882454	[666]	[539,480,890,797]	-4	hSpCas9	negative selection	8502367
213008311	213008334	1	-	27260156	RDES	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.5523139161014172	[235]	[316,283,387,659]	8	hSpCas9	negative selection	8502368
213007138	213007161	1	-	27260156	RDES	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.03461380420126936	[1190]	[1095,1239,1385,1705]	0	hSpCas9	negative selection	8502369
213013129	213013152	1	-	27260156	PC3	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.08864740522585035	[153]	[51,270,313,104]	2	hSpCas9	negative selection	8559336
213013186	213013209	1	+	27260156	PC3	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.005363631490604259	[193]	[105,141,375,244]	0	hSpCas9	negative selection	8559337
213008253	213008276	1	+	27260156	PC3	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.31937403786426793	[319]	[240,402,585,468]	6	hSpCas9	negative selection	8559338
213007125	213007148	1	+	27260156	PC3	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.05502462090030752	[666]	[269,750,1308,599]	-1	hSpCas9	negative selection	8623618
213008311	213008334	1	-	27260156	PC3	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.1705123705776328	[235]	[150,323,381,269]	4	hSpCas9	negative selection	8623619
213007138	213007161	1	-	27260156	PC3	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.2065212086232513	[1190]	[968,1256,2091,1480]	4	hSpCas9	negative selection	8623620
213013129	213013152	1	-	27260156	PATU8988T	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.7086219116370547	[153]	[164,261,211,343]	9	hSpCas9	negative selection	8680587
213013186	213013209	1	+	27260156	PATU8988T	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.5650804194629389	[193]	[81,82,58,292]	-7	hSpCas9	negative selection	8680588
213008253	213008276	1	+	27260156	PATU8988T	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.4247956328696292	[319]	[499,446,300,416]	7	hSpCas9	negative selection	8680589
213007125	213007148	1	+	27260156	PATU8988T	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	0.10107114153141972	[666]	[686,712,502,881]	1	hSpCas9	negative selection	8744869
213008311	213008334	1	-	27260156	PATU8988T	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.851649328579943	[235]	[477,487,277,410]	9	hSpCas9	negative selection	8744870
213007138	213007161	1	-	27260156	PATU8988T	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	0.08571002639059566	[1190]	[1388,1134,1456,863]	1	hSpCas9	negative selection	8744871
213013129	213013152	1	-	27260156	T47D	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.162105733805324	[153]	[123,182,246,250]	3	hSpCas9	negative selection	8801838
213013186	213013209	1	+	27260156	T47D	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.4690008339300564	[193]	[194,122,185,151]	-7	hSpCas9	negative selection	8801839
213008253	213008276	1	+	27260156	T47D	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.22598896049659167	[319]	[497,361,460,428]	5	hSpCas9	negative selection	8801840
213007125	213007148	1	+	27260156	T47D	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.14931847743588378	[666]	[698,756,607,735]	-3	hSpCas9	negative selection	8866120
213008311	213008334	1	-	27260156	T47D	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.17539874694960245	[235]	[388,292,263,297]	4	hSpCas9	negative selection	8866121
213007138	213007161	1	-	27260156	T47D	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.13376646051638197	[1190]	[1257,1179,1379,1244]	-3	hSpCas9	negative selection	8866122
213013129	213013152	1	-	27260156	SU8686	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.059776741149681456	[153]	[90,89,231,195]	-1	hSpCas9	negative selection	8923089
213013186	213013209	1	+	27260156	SU8686	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	0.559249824517835	[193]	[297,233,261,352]	8	hSpCas9	negative selection	8923090
213008253	213008276	1	+	27260156	SU8686	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.40514162717802393	[319]	[341,311,490,583]	6	hSpCas9	negative selection	8923091
213007125	213007148	1	+	27260156	SU8686	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	0.05230352939310812	[666]	[688,608,743,710]	0	hSpCas9	negative selection	8987371
213008311	213008334	1	-	27260156	SU8686	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.003677281341921357	[235]	[254,187,263,233]	0	hSpCas9	negative selection	8987372
213007138	213007161	1	-	27260156	SU8686	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.1858609157925446	[1190]	[1044,802,1136,1221]	-3	hSpCas9	negative selection	8987373
213013129	213013152	1	-	27260156	SKES1	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.03656056574160815	[153]	[138,161,142,179]	0	hSpCas9	negative selection	9044340
213013186	213013209	1	+	27260156	SKES1	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.3731379875244525	[193]	[139,135,209,110]	-7	hSpCas9	negative selection	9044341
213008253	213008276	1	+	27260156	SKES1	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.30333950054784975	[319]	[474,395,350,364]	6	hSpCas9	negative selection	9044342
213007125	213007148	1	+	27260156	SKES1	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.19345912213044808	[666]	[742,676,365,572]	-4	hSpCas9	negative selection	9108622
213008311	213008334	1	-	27260156	SKES1	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.45690691288844365	[235]	[395,295,452,167]	8	hSpCas9	negative selection	9108623
213007138	213007161	1	-	27260156	SKES1	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.22248833721853334	[1190]	[1090,1192,1039,795]	-5	hSpCas9	negative selection	9108624
213013129	213013152	1	-	27260156	TOV112D	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.0001249447003091042	[153]	[135,95,218,149]	0	hSpCas9	negative selection	9165591
213013186	213013209	1	+	27260156	TOV112D	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.15227024997636018	[193]	[111,133,272,164]	-3	hSpCas9	negative selection	9165592
213008253	213008276	1	+	27260156	TOV112D	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.32662931667547823	[319]	[549,346,415,295]	6	hSpCas9	negative selection	9165593
213007125	213007148	1	+	27260156	TOV112D	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.023146339958906414	[666]	[920,610,692,420]	0	hSpCas9	negative selection	9229873
213008311	213008334	1	-	27260156	TOV112D	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	-0.09117332399922873	[235]	[357,157,219,148]	-2	hSpCas9	negative selection	9229874
213007138	213007161	1	-	27260156	TOV112D	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.32945109077271817	[1190]	[865,1458,744,846]	-6	hSpCas9	negative selection	9229875
213013129	213013152	1	-	27260156	TC71	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.12960719264413445	[153]	[118,171,174,262]	3	hSpCas9	negative selection	9286842
213013186	213013209	1	+	27260156	TC71	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-0.10636830863389668	[193]	[176,179,212,202]	-3	hSpCas9	negative selection	9286843
213008253	213008276	1	+	27260156	TC71	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	0.25333021645204673	[319]	[412,410,407,402]	6	hSpCas9	negative selection	9286844
213007125	213007148	1	+	27260156	TC71	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.004577140758942	[666]	[747,805,558,743]	0	hSpCas9	negative selection	9351124
213008311	213008334	1	-	27260156	TC71	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.4296031309202215	[235]	[394,312,358,290]	8	hSpCas9	negative selection	9351125
213007138	213007161	1	-	27260156	TC71	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.11590849405760939	[1190]	[1023,1375,1159,1154]	-3	hSpCas9	negative selection	9351126
213013129	213013152	1	-	27260156	TC32	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.36905148035887647	[153]	[98,91,169,98]	-6	hSpCas9	negative selection	9408093
213013186	213013209	1	+	27260156	TC32	viability	CAGGTCTCCAGTTACAGTACTGG	ANGEL2	ENSG00000174606	-1.2091063915019589	[193]	[109,48,111,50]	-9	hSpCas9	negative selection	9408094
213008253	213008276	1	+	27260156	TC32	viability	CTAAAACTCCAGTGTAATACTGG	ANGEL2	ENSG00000174606	-0.12490055382616017	[319]	[263,121,451,344]	-2	hSpCas9	negative selection	9408095
213007125	213007148	1	+	27260156	TC32	viability	GTACCCAGTGATTCCAAACTTGG	ANGEL2	ENSG00000174606	-0.47726665311256194	[666]	[365,382,542,538]	-7	hSpCas9	negative selection	9472375
213008311	213008334	1	-	27260156	TC32	viability	TATACTTTCACAAGATTTACTGG	ANGEL2	ENSG00000174606	0.3570994647880622	[235]	[361,159,369,278]	6	hSpCas9	negative selection	9472376
213007138	213007161	1	-	27260156	TC32	viability	AGCAGAGATCAGGCCAAGTTTGG	ANGEL2	ENSG00000174606	-0.34016503461536485	[1190]	[997,672,1037,862]	-6	hSpCas9	negative selection	9472377
212997213	212997236	1	+	27869803	HPAFII	viability after 27 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.1547815151817704	[76]	[19,49,NaN]	-1	hSpCas9	negative selection	9532047
213005214	213005237	1	-	27869803	HPAFII	viability after 27 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.4846692275315211	[375]	[209,83,NaN]	-4	hSpCas9	negative selection	9532048
213008260	213008283	1	+	27869803	HPAFII	viability after 27 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.3402740131862483	[83]	[32,74,NaN]	2	hSpCas9	negative selection	9532049
213008276	213008299	1	-	27869803	HPAFII	viability after 27 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.4982060695945862	[189]	[193,96,NaN]	4	hSpCas9	negative selection	9532050
213013302	213013325	1	-	27869803	HPAFII	viability after 27 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.1571937992793864	[87]	[28,164,NaN]	8	hSpCas9	negative selection	9532051
213015660	213015683	1	-	27869803	HPAFII	viability after 27 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-1.315401882291176	[138]	[30,27,NaN]	-7	hSpCas9	negative selection	9532052
212997213	212997236	1	+	27869803	HPAFII	viability after 15 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.31855809510785105	[76]	[117,93,NaN]	3	hSpCas9	negative selection	9614496
213005214	213005237	1	-	27869803	HPAFII	viability after 15 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.5334098299925963	[375]	[449,172,NaN]	-5	hSpCas9	negative selection	9614497
213008260	213008283	1	+	27869803	HPAFII	viability after 15 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.305705074025054	[83]	[126,101,NaN]	3	hSpCas9	negative selection	9614498
213008276	213008299	1	-	27869803	HPAFII	viability after 15 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.7526719530104304	[189]	[586,192,NaN]	8	hSpCas9	negative selection	9614499
213013302	213013325	1	-	27869803	HPAFII	viability after 15 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.2760204826078656	[87]	[124,107,NaN]	3	hSpCas9	negative selection	9614500
213015660	213015683	1	-	27869803	HPAFII	viability after 15 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-1.5245849495624733	[138]	[128,3,NaN]	-8	hSpCas9	negative selection	9614501
212997213	212997236	1	+	27869803	ASPC1	viability after 36 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-2.3303621735057023	[248]	[9,43,0]	-9	hSpCas9	negative selection	9696945
213005214	213005237	1	-	27869803	ASPC1	viability after 36 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.028451085425465282	[629]	[309,150,219]	0	hSpCas9	negative selection	9696946
213008260	213008283	1	+	27869803	ASPC1	viability after 36 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-2.623566433662027	[237]	[26,6,8]	-9	hSpCas9	negative selection	9696947
213008276	213008299	1	-	27869803	ASPC1	viability after 36 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.6646364327862488	[472]	[133,126,63]	-6	hSpCas9	negative selection	9696948
213013302	213013325	1	-	27869803	ASPC1	viability after 36 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	-0.31075423450895245	[271]	[56,27,127]	-3	hSpCas9	negative selection	9696949
213015660	213015683	1	-	27869803	ASPC1	viability after 36 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-0.28296838597769836	[302]	[49,9,172]	-3	hSpCas9	negative selection	9696950
212997213	212997236	1	+	27869803	PATU8988S	viability after 35 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.13830380299261846	[182]	[51,81,NaN]	-1	hSpCas9	negative selection	9779394
213005214	213005237	1	-	27869803	PATU8988S	viability after 35 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.9814380367505086	[670]	[80,192,NaN]	-7	hSpCas9	negative selection	9779395
213008260	213008283	1	+	27869803	PATU8988S	viability after 35 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.16814966039105572	[219]	[124,73,NaN]	2	hSpCas9	negative selection	9779396
213008276	213008299	1	-	27869803	PATU8988S	viability after 35 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-1.3395198257915109	[461]	[84,61,NaN]	-8	hSpCas9	negative selection	9779397
213013302	213013325	1	-	27869803	PATU8988S	viability after 35 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	-0.17184217735764817	[192]	[69,67,NaN]	-2	hSpCas9	negative selection	9779398
213015660	213015683	1	-	27869803	PATU8988S	viability after 35 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-0.3182117759550147	[242]	[76,79,NaN]	-3	hSpCas9	negative selection	9779399
212997213	212997236	1	+	27869803	PATU8988S	viability after 31 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.6959989462147183	[182]	[59,25,NaN]	-6	hSpCas9	negative selection	9861843
213005214	213005237	1	-	27869803	PATU8988S	viability after 31 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.5735398916007193	[670]	[126,246,NaN]	-6	hSpCas9	negative selection	9861844
213008260	213008283	1	+	27869803	PATU8988S	viability after 31 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-0.04827533356549152	[219]	[68,104,NaN]	0	hSpCas9	negative selection	9861845
213008276	213008299	1	-	27869803	PATU8988S	viability after 31 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.8397980436236565	[461]	[138,56,NaN]	-7	hSpCas9	negative selection	9861846
213013302	213013325	1	-	27869803	PATU8988S	viability after 31 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	0.5106035778759686	[192]	[95,126,NaN]	6	hSpCas9	negative selection	9861847
213015660	213015683	1	-	27869803	PATU8988S	viability after 31 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-1.00631209585563	[242]	[27,73,NaN]	-7	hSpCas9	negative selection	9861848
212997213	212997236	1	+	27869803	HPAFII	viability after 35 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.6172420855572252	[76]	[0,125,NaN]	4	hSpCas9	negative selection	9944292
213005214	213005237	1	-	27869803	HPAFII	viability after 35 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.3009080970658419	[375]	[241,55,NaN]	-2	hSpCas9	negative selection	9944293
213008260	213008283	1	+	27869803	HPAFII	viability after 35 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	-0.25031765696779185	[83]	[7,66,NaN]	-1	hSpCas9	negative selection	9944294
213008276	213008299	1	-	27869803	HPAFII	viability after 35 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	-0.09673786728062311	[189]	[104,72,NaN]	0	hSpCas9	negative selection	9944295
213013302	213013325	1	-	27869803	HPAFII	viability after 35 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.9052339744977451	[87]	[21,329,NaN]	9	hSpCas9	negative selection	9944296
213015660	213015683	1	-	27869803	HPAFII	viability after 35 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-1.4423466611360352	[138]	[47,0,NaN]	-7	hSpCas9	negative selection	9944297
212997213	212997236	1	+	27869803	HPAFII	viability after 31 days	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.5662625928910874	[76]	[18,112,NaN]	4	hSpCas9	negative selection	10026741
213005214	213005237	1	-	27869803	HPAFII	viability after 31 days	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.4961135266734362	[375]	[207,85,NaN]	-3	hSpCas9	negative selection	10026742
213008260	213008283	1	+	27869803	HPAFII	viability after 31 days	TCCAGTGTAATACTGGCCGCCGG	ANGEL2	ENSG00000174606	0.3059473851132637	[83]	[30,87,NaN]	2	hSpCas9	negative selection	10026743
213008276	213008299	1	-	27869803	HPAFII	viability after 31 days	ACCTTTATAGACATTGCCGGCGG	ANGEL2	ENSG00000174606	0.07857860853717707	[189]	[125,97,NaN]	0	hSpCas9	negative selection	10026744
213013302	213013325	1	-	27869803	HPAFII	viability after 31 days	TCTAGTTGTATGAGGTGGCCTGG	ANGEL2	ENSG00000174606	1.4787255152760774	[87]	[17,267,NaN]	9	hSpCas9	negative selection	10026745
213015660	213015683	1	-	27869803	HPAFII	viability after 31 days	GGAGGGCGAAGATGGAAGCCTGG	ANGEL2	ENSG00000174606	-1.0633614806731952	[138]	[66,4,NaN]	-6	hSpCas9	negative selection	10026746
213013361	213013384	1	-	28162770	P31FUJ	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.8797515920312355	[320]	[204]	-6	hSpCas9	negative selection	10110280
213005337	213005360	1	+	28162770	P31FUJ	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.22530401675635114	[395]	[543]	2	hSpCas9	negative selection	10110281
213000345	213000368	1	-	28162770	P31FUJ	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.37140744264388537	[130]	[118]	-3	hSpCas9	negative selection	10110282
213015623	213015646	1	-	28162770	P31FUJ	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.3381242366199161	[240]	[357]	3	hSpCas9	negative selection	10110283
213015614	213015637	1	+	28162770	P31FUJ	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.548557509110281	[191]	[329]	6	hSpCas9	negative selection	10110284
213005145	213005168	1	-	28162770	P31FUJ	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.6123960687878979	[171]	[308]	7	hSpCas9	negative selection	10110285
212997213	212997236	1	+	28162770	P31FUJ	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.0019183221842911102	[120]	[141]	0	hSpCas9	negative selection	10110286
213013129	213013152	1	-	28162770	P31FUJ	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.05670441278060612	[368]	[450]	0	hSpCas9	negative selection	10110287
213005214	213005237	1	-	28162770	P31FUJ	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.19461901932029768	[231]	[311]	2	hSpCas9	negative selection	10110288
213013218	213013241	1	+	28162770	P31FUJ	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	0.019963865965587857	[46]	[55]	0	hSpCas9	negative selection	10110289
213013361	213013384	1	-	28162770	TF1	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10279646
213005337	213005360	1	+	28162770	TF1	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[351]	1	hSpCas9	negative selection	10279647
213000345	213000368	1	-	28162770	TF1	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10279648
213015623	213015646	1	-	28162770	TF1	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10279649
213015614	213015637	1	+	28162770	TF1	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[102]	1	hSpCas9	negative selection	10279650
213005145	213005168	1	-	28162770	TF1	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[305]	1	hSpCas9	negative selection	10279651
212997213	212997236	1	+	28162770	TF1	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10279652
213013129	213013152	1	-	28162770	TF1	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[224]	1	hSpCas9	negative selection	10279653
213005214	213005237	1	-	28162770	TF1	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10279654
213013218	213013241	1	+	28162770	TF1	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	NaN	[NaN]	[99]	1	hSpCas9	negative selection	10279655
213013361	213013384	1	-	28162770	SKM1	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.08828176335945337	[88]	[147]	0	hSpCas9	negative selection	10449012
213005337	213005360	1	+	28162770	SKM1	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	-0.21194821633801894	[75]	[115]	-2	hSpCas9	negative selection	10449013
213000345	213000368	1	-	28162770	SKM1	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.07490480901389063	[28]	[53]	0	hSpCas9	negative selection	10449014
213015623	213015646	1	-	28162770	SKM1	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.05574255192699651	[79]	[146]	0	hSpCas9	negative selection	10449015
213015614	213015637	1	+	28162770	SKM1	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.17799830197799427	[37]	[75]	1	hSpCas9	negative selection	10449016
213005145	213005168	1	-	28162770	SKM1	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.13219461236486985	[63]	[123]	1	hSpCas9	negative selection	10449017
212997213	212997236	1	+	28162770	SKM1	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.5565099252317243	[29]	[77]	5	hSpCas9	negative selection	10449018
213013129	213013152	1	-	28162770	SKM1	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.34489561072273883	[52]	[118]	3	hSpCas9	negative selection	10449019
213005214	213005237	1	-	28162770	SKM1	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.19548572870683556	[40]	[82]	2	hSpCas9	negative selection	10449020
213013218	213013241	1	+	28162770	SKM1	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-3.2814333166593026	[10]	[1]	-9	hSpCas9	negative selection	10449021
213013361	213013384	1	-	28162770	SKM1	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.08828176335945337	[88]	[147]	0	hSpCas9	negative selection	10618378
213005337	213005360	1	+	28162770	SKM1	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	-0.21194821633801894	[75]	[115]	-2	hSpCas9	negative selection	10618379
213000345	213000368	1	-	28162770	SKM1	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.07490480901389063	[28]	[53]	0	hSpCas9	negative selection	10618380
213015623	213015646	1	-	28162770	SKM1	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.05574255192699651	[79]	[146]	0	hSpCas9	negative selection	10618381
213015614	213015637	1	+	28162770	SKM1	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.17799830197799427	[37]	[75]	1	hSpCas9	negative selection	10618382
213005145	213005168	1	-	28162770	SKM1	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.13219461236486985	[63]	[123]	1	hSpCas9	negative selection	10618383
212997213	212997236	1	+	28162770	SKM1	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.5565099252317243	[29]	[77]	5	hSpCas9	negative selection	10618384
213013129	213013152	1	-	28162770	SKM1	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.34489561072273883	[52]	[118]	3	hSpCas9	negative selection	10618385
213005214	213005237	1	-	28162770	SKM1	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.19548572870683556	[40]	[82]	2	hSpCas9	negative selection	10618386
213013218	213013241	1	+	28162770	SKM1	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-3.2814333166593026	[10]	[1]	-9	hSpCas9	negative selection	10618387
213013361	213013384	1	-	28162770	PL21	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.4726184907268498	[270]	[84]	-3	hSpCas9	negative selection	10787744
213005337	213005360	1	+	28162770	PL21	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.18964724067167782	[275]	[136]	1	hSpCas9	negative selection	10787745
213000345	213000368	1	-	28162770	PL21	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-1.1456352223524102	[121]	[23]	-6	hSpCas9	negative selection	10787746
213015623	213015646	1	-	28162770	PL21	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.12010011656420283	[314]	[148]	1	hSpCas9	negative selection	10787747
213015614	213015637	1	+	28162770	PL21	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-1.5117349987140556	[189]	[28]	-7	hSpCas9	negative selection	10787748
213005145	213005168	1	-	28162770	PL21	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	-0.0028004441809554026	[220]	[95]	0	hSpCas9	negative selection	10787749
212997213	212997236	1	+	28162770	PL21	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.2590333035428888	[95]	[49]	2	hSpCas9	negative selection	10787750
213013129	213013152	1	-	28162770	PL21	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.2678842211251543	[207]	[108]	2	hSpCas9	negative selection	10787751
213005214	213005237	1	-	28162770	PL21	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.9334939551031474	[159]	[132]	7	hSpCas9	negative selection	10787752
213013218	213013241	1	+	28162770	PL21	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	2.007494536546924	[39]	[69]	9	hSpCas9	negative selection	10787753
213013361	213013384	1	-	28162770	P31FUJ	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.8797515920312355	[320]	[204]	-6	hSpCas9	negative selection	10957110
213005337	213005360	1	+	28162770	P31FUJ	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.22530401675635114	[395]	[543]	2	hSpCas9	negative selection	10957111
213000345	213000368	1	-	28162770	P31FUJ	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.37140744264388537	[130]	[118]	-3	hSpCas9	negative selection	10957112
213015623	213015646	1	-	28162770	P31FUJ	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.3381242366199161	[240]	[357]	3	hSpCas9	negative selection	10957113
213015614	213015637	1	+	28162770	P31FUJ	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.548557509110281	[191]	[329]	6	hSpCas9	negative selection	10957114
213005145	213005168	1	-	28162770	P31FUJ	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.6123960687878979	[171]	[308]	7	hSpCas9	negative selection	10957115
212997213	212997236	1	+	28162770	P31FUJ	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.0019183221842911102	[120]	[141]	0	hSpCas9	negative selection	10957116
213013129	213013152	1	-	28162770	P31FUJ	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.05670441278060612	[368]	[450]	0	hSpCas9	negative selection	10957117
213005214	213005237	1	-	28162770	P31FUJ	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.19461901932029768	[231]	[311]	2	hSpCas9	negative selection	10957118
213013218	213013241	1	+	28162770	P31FUJ	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	0.019963865965587857	[46]	[55]	0	hSpCas9	negative selection	10957119
213013361	213013384	1	-	28162770	OCIAML5	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.2854825994576953	[157]	[233]	-2	hSpCas9	negative selection	11126476
213005337	213005360	1	+	28162770	OCIAML5	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	-0.18488930685465332	[215]	[342]	-1	hSpCas9	negative selection	11126477
213000345	213000368	1	-	28162770	OCIAML5	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.14793342913600283	[71]	[143]	1	hSpCas9	negative selection	11126478
213015623	213015646	1	-	28162770	OCIAML5	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	-0.2422722171629053	[191]	[292]	-2	hSpCas9	negative selection	11126479
213015614	213015637	1	+	28162770	OCIAML5	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-1.9859223175987872	[78]	[35]	-8	hSpCas9	negative selection	11126480
213005145	213005168	1	-	28162770	OCIAML5	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.4006994995159697	[140]	[335]	3	hSpCas9	negative selection	11126481
212997213	212997236	1	+	28162770	OCIAML5	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	1.6758649848207803	[42]	[247]	9	hSpCas9	negative selection	11126482
213013129	213013152	1	-	28162770	OCIAML5	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.30236209425514726	[207]	[462]	2	hSpCas9	negative selection	11126483
213005214	213005237	1	-	28162770	OCIAML5	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.6588953484133823	[79]	[227]	6	hSpCas9	negative selection	11126484
213013218	213013241	1	+	28162770	OCIAML5	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-0.04910341792355055	[46]	[81]	0	hSpCas9	negative selection	11126485
213013361	213013384	1	-	28162770	EOL1	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.8465541621232217	[726]	[212]	-5	hSpCas9	negative selection	11295842
213005337	213005360	1	+	28162770	EOL1	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.0466493793017225	[350]	[190]	0	hSpCas9	negative selection	11295843
213000345	213000368	1	-	28162770	EOL1	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.8058451686721853	[218]	[65]	-5	hSpCas9	negative selection	11295844
213015623	213015646	1	-	28162770	EOL1	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.22992469019404915	[525]	[324]	2	hSpCas9	negative selection	11295845
213015614	213015637	1	+	28162770	EOL1	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.009210168639918637	[363]	[192]	0	hSpCas9	negative selection	11295846
213005145	213005168	1	-	28162770	EOL1	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.6111311765386898	[337]	[271]	5	hSpCas9	negative selection	11295847
212997213	212997236	1	+	28162770	EOL1	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	1.7223589209572676	[129]	[225]	9	hSpCas9	negative selection	11295848
213013129	213013152	1	-	28162770	EOL1	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.20236023277560763	[258]	[156]	1	hSpCas9	negative selection	11295849
213005214	213005237	1	-	28162770	EOL1	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-1.011637130832022	[198]	[51]	-6	hSpCas9	negative selection	11295850
213013218	213013241	1	+	28162770	EOL1	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-1.3081129852197404	[46]	[9]	-7	hSpCas9	negative selection	11295851
213013361	213013384	1	-	28162770	MOLM13	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.3613347204736157	[564]	[317]	-2	hSpCas9	negative selection	11465208
213005337	213005360	1	+	28162770	MOLM13	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.42632739090284766	[492]	[478]	3	hSpCas9	negative selection	11465209
213000345	213000368	1	-	28162770	MOLM13	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	1.324931427702536	[158]	[287]	8	hSpCas9	negative selection	11465210
213015623	213015646	1	-	28162770	MOLM13	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.48126841134577886	[321]	[324]	3	hSpCas9	negative selection	11465211
213015614	213015637	1	+	28162770	MOLM13	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-0.13279135292350802	[322]	[212]	-1	hSpCas9	negative selection	11465212
213005145	213005168	1	-	28162770	MOLM13	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	1.026662358284872	[314]	[463]	7	hSpCas9	negative selection	11465213
212997213	212997236	1	+	28162770	MOLM13	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.6665733759683151	[148]	[170]	5	hSpCas9	negative selection	11465214
213013129	213013152	1	-	28162770	MOLM13	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.6229640489065347	[425]	[199]	-4	hSpCas9	negative selection	11465215
213005214	213005237	1	-	28162770	MOLM13	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	1.4805632115796894	[169]	[342]	9	hSpCas9	negative selection	11465216
213013218	213013241	1	+	28162770	MOLM13	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	2.198831188083015	[71]	[238]	9	hSpCas9	negative selection	11465217
213013361	213013384	1	-	28162770	HEL	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	0.7129649683253924	[420]	[441]	6	hSpCas9	negative selection	11634574
213005337	213005360	1	+	28162770	HEL	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	-0.36487435210951846	[379]	[188]	-3	hSpCas9	negative selection	11634575
213000345	213000368	1	-	28162770	HEL	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.9281410508626051	[127]	[155]	7	hSpCas9	negative selection	11634576
213015623	213015646	1	-	28162770	HEL	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.11892498680418151	[357]	[248]	1	hSpCas9	negative selection	11634577
213015614	213015637	1	+	28162770	HEL	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.9149917678635295	[259]	[313]	7	hSpCas9	negative selection	11634578
213005145	213005168	1	-	28162770	HEL	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	1.5461903436421045	[223]	[418]	9	hSpCas9	negative selection	11634579
212997213	212997236	1	+	28162770	HEL	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.2097794247242507	[107]	[79]	1	hSpCas9	negative selection	11634580
213013129	213013152	1	-	28162770	HEL	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.05866557694290442	[373]	[229]	0	hSpCas9	negative selection	11634581
213005214	213005237	1	-	28162770	HEL	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.6882534912527258	[155]	[160]	6	hSpCas9	negative selection	11634582
213013218	213013241	1	+	28162770	HEL	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-1.2152421631272152	[57]	[15]	-6	hSpCas9	negative selection	11634583
213013361	213013384	1	-	28162770	MV411	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-0.7402140567895796	[348]	[175]	-5	hSpCas9	negative selection	11803940
213005337	213005360	1	+	28162770	MV411	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.5527827614745336	[279]	[345]	5	hSpCas9	negative selection	11803941
213000345	213000368	1	-	28162770	MV411	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.8963982217908759	[136]	[61]	-6	hSpCas9	negative selection	11803942
213015623	213015646	1	-	28162770	MV411	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	-0.6995440669177335	[373]	[193]	-5	hSpCas9	negative selection	11803943
213015614	213015637	1	+	28162770	MV411	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-0.7025217667176292	[169]	[87]	-5	hSpCas9	negative selection	11803944
213005145	213005168	1	-	28162770	MV411	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.19789808998146025	[236]	[228]	1	hSpCas9	negative selection	11803945
212997213	212997236	1	+	28162770	MV411	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.33385230260024845	[80]	[85]	3	hSpCas9	negative selection	11803946
213013129	213013152	1	-	28162770	MV411	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.24115128793534418	[229]	[228]	2	hSpCas9	negative selection	11803947
213005214	213005237	1	-	28162770	MV411	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.5390411088133399	[124]	[152]	5	hSpCas9	negative selection	11803948
213013218	213013241	1	+	28162770	MV411	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	1.2474375507827753	[28]	[57]	9	hSpCas9	negative selection	11803949
213013361	213013384	1	-	28162770	MONOMAC1	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	0.3357294425361743	[196]	[284]	3	hSpCas9	negative selection	11973306
213005337	213005360	1	+	28162770	MONOMAC1	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.9993603657439499	[143]	[329]	8	hSpCas9	negative selection	11973307
213000345	213000368	1	-	28162770	MONOMAC1	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	-0.9340024412257597	[99]	[59]	-6	hSpCas9	negative selection	11973308
213015623	213015646	1	-	28162770	MONOMAC1	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	0.34549038734120596	[183]	[267]	3	hSpCas9	negative selection	11973309
213015614	213015637	1	+	28162770	MONOMAC1	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	-0.9993561792198595	[142]	[81]	-7	hSpCas9	negative selection	11973310
213005145	213005168	1	-	28162770	MONOMAC1	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.03834121587137457	[157]	[185]	0	hSpCas9	negative selection	11973311
212997213	212997236	1	+	28162770	MONOMAC1	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-0.8974765652006459	[77]	[47]	-6	hSpCas9	negative selection	11973312
213013129	213013152	1	-	28162770	MONOMAC1	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.2350046972585741	[153]	[149]	-2	hSpCas9	negative selection	11973313
213005214	213005237	1	-	28162770	MONOMAC1	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.19703684705955377	[95]	[95]	-2	hSpCas9	negative selection	11973314
213013218	213013241	1	+	28162770	MONOMAC1	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-1.31251406447949	[25]	[11]	-7	hSpCas9	negative selection	11973315
213013361	213013384	1	-	28162770	OCIAML2	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	-1.4012084242846814	[70]	[148]	-7	hSpCas9	negative selection	12142672
213005337	213005360	1	+	28162770	OCIAML2	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.2783084105901211	[35]	[241]	2	hSpCas9	negative selection	12142673
213000345	213000368	1	-	28162770	OCIAML2	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.43626077036635735	[17]	[134]	4	hSpCas9	negative selection	12142674
213015623	213015646	1	-	28162770	OCIAML2	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	-0.47849194301513165	[45]	[182]	-4	hSpCas9	negative selection	12142675
213015614	213015637	1	+	28162770	OCIAML2	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.534664474427352	[33]	[272]	5	hSpCas9	negative selection	12142676
213005145	213005168	1	-	28162770	OCIAML2	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	0.5138293238620607	[34]	[276]	5	hSpCas9	negative selection	12142677
212997213	212997236	1	+	28162770	OCIAML2	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	0.21587070194105729	[15]	[102]	2	hSpCas9	negative selection	12142678
213013129	213013152	1	-	28162770	OCIAML2	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	-0.05354449731445887	[43]	[234]	0	hSpCas9	negative selection	12142679
213005214	213005237	1	-	28162770	OCIAML2	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	0.6723281285998817	[23]	[211]	6	hSpCas9	negative selection	12142680
213013218	213013241	1	+	28162770	OCIAML2	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-0.43110146105552394	[8]	[36]	-3	hSpCas9	negative selection	12142681
213013361	213013384	1	-	28162770	OCIAML3	viability	GCAGAGACTGGACTACACCGTGG	ANGEL2	ENSG00000174606	0.08925693400879675	[103]	[333]	0	hSpCas9	negative selection	12312038
213005337	213005360	1	+	28162770	OCIAML3	viability	TCAGGGCGGAAGAATTCCACTGG	ANGEL2	ENSG00000174606	0.30411274565662305	[87]	[327]	3	hSpCas9	negative selection	12312039
213000345	213000368	1	-	28162770	OCIAML3	viability	AACACAGCTGAAGCAAACAGAGG	ANGEL2	ENSG00000174606	0.8181182635347775	[30]	[164]	7	hSpCas9	negative selection	12312040
213015623	213015646	1	-	28162770	OCIAML3	viability	GGGCTACGGCCACTGTGTGGTGG	ANGEL2	ENSG00000174606	-0.07554055138991372	[73]	[211]	0	hSpCas9	negative selection	12312041
213015614	213015637	1	+	28162770	OCIAML3	viability	GGCCTCTTCCCACCACACAGTGG	ANGEL2	ENSG00000174606	0.32192809488736235	[52]	[199]	3	hSpCas9	negative selection	12312042
213005145	213005168	1	-	28162770	OCIAML3	viability	AGTGTTGCCCACCAGAAAGATGG	ANGEL2	ENSG00000174606	-1.2057370506081047	[67]	[88]	-7	hSpCas9	negative selection	12312043
212997213	212997236	1	+	28162770	OCIAML3	viability	GGCACTTCGGGAATGACAGGTGG	ANGEL2	ENSG00000174606	-1.364525794201396	[28]	[33]	-7	hSpCas9	negative selection	12312044
213013129	213013152	1	-	28162770	OCIAML3	viability	TAGTTACGTCATGAACGCTGAGG	ANGEL2	ENSG00000174606	0.13905349938612704	[73]	[245]	1	hSpCas9	negative selection	12312045
213005214	213005237	1	-	28162770	OCIAML3	viability	CTGTTGTATAATCCAAGGCGAGG	ANGEL2	ENSG00000174606	-0.26538489286279254	[42]	[107]	-2	hSpCas9	negative selection	12312046
213013218	213013241	1	+	28162770	OCIAML3	viability	CTAGACTCAAACAAACAGGGTGG	ANGEL2	ENSG00000174606	-1.0534392589614603	[10]	[15]	-6	hSpCas9	negative selection	12312047