Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:187
• Symbol:APLNR
• Description:apelin receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/APLNR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
57236477	57236500	11	+	26472758	Jiyoye	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.8284528669872686	[145]	[61]	-5	hSpCas9	negative selection	8180
57236513	57236536	11	+	26472758	Jiyoye	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	-0.7584106842121016	[82]	[36]	-5	hSpCas9	negative selection	8181
57236366	57236389	11	+	26472758	Jiyoye	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	0.5206334312891573	[109]	[118]	4	hSpCas9	negative selection	8182
57236921	57236944	11	-	26472758	Jiyoye	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	-0.4689529603319582	[144]	[78]	-3	hSpCas9	negative selection	8183
57236855	57236878	11	+	26472758	Jiyoye	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	0.9546631768083665	[38]	[56]	6	hSpCas9	negative selection	8184
57236417	57236440	11	+	26472758	Jiyoye	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	-0.13445968755118198	[245]	[168]	-1	hSpCas9	negative selection	8185
57236131	57236154	11	+	26472758	Jiyoye	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	1.2587835416132023	[132]	[239]	7	hSpCas9	negative selection	8186
57235986	57236009	11	-	26472758	Jiyoye	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	1.1727101278688505	[19]	[33]	7	hSpCas9	negative selection	8187
57236753	57236776	11	+	26472758	Jiyoye	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	1.001918903019615	[48]	[73]	6	hSpCas9	negative selection	8188
57236621	57236644	11	+	26472758	Jiyoye	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.6702097873396673	[89]	[107]	5	hSpCas9	negative selection	8189
57236477	57236500	11	+	26472758	KBM7	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	0.2400752348681291	[519,236]	[265,146]	2	hSpCas9	negative selection	199298
57236513	57236536	11	+	26472758	KBM7	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	0.05197776420258238	[276,217]	[180,64]	0	hSpCas9	negative selection	199299
57236366	57236389	11	+	26472758	KBM7	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.5406314587211775	[403,272]	[92,120]	-5	hSpCas9	negative selection	199300
57236921	57236944	11	-	26472758	KBM7	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.5986684767265665	[492,385]	[233,378]	6	hSpCas9	negative selection	199301
57236855	57236878	11	+	26472758	KBM7	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	1.181100937384716	[164,164]	[199,155]	9	hSpCas9	negative selection	199302
57236417	57236440	11	+	26472758	KBM7	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	-0.39683273333251806	[766,516]	[266,188]	-4	hSpCas9	negative selection	199303
57236131	57236154	11	+	26472758	KBM7	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	-0.585658457417508	[1029,638]	[209,297]	-5	hSpCas9	negative selection	199304
57235986	57236009	11	-	26472758	KBM7	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	-0.3752953882085489	[218,273]	[84,95]	-3	hSpCas9	negative selection	199305
57236753	57236776	11	+	26472758	KBM7	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	-0.1788553326999271	[460,333]	[111,208]	-2	hSpCas9	negative selection	199306
57236621	57236644	11	+	26472758	KBM7	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.19364873978441285	[572,538]	[308,290]	2	hSpCas9	negative selection	199307
57236477	57236500	11	+	26472758	Raji	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.2593987952980232	[293]	[56]	-2	hSpCas9	negative selection	390416
57236513	57236536	11	+	26472758	Raji	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	-2.031380534582252	[228]	[12]	-8	hSpCas9	negative selection	390417
57236366	57236389	11	+	26472758	Raji	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	0.4001652846014453	[159]	[48]	4	hSpCas9	negative selection	390418
57236921	57236944	11	-	26472758	Raji	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.8473206960710964	[193]	[80]	7	hSpCas9	negative selection	390419
57236855	57236878	11	+	26472758	Raji	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	-0.35204808326369785	[109]	[19]	-3	hSpCas9	negative selection	390420
57236417	57236440	11	+	26472758	Raji	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.08827471242589469	[303]	[74]	0	hSpCas9	negative selection	390421
57236131	57236154	11	+	26472758	Raji	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	-0.10561018796059896	[356]	[76]	-1	hSpCas9	negative selection	390422
57235986	57236009	11	-	26472758	Raji	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	1.1451855680859837	[112]	[57]	8	hSpCas9	negative selection	390423
57236753	57236776	11	+	26472758	Raji	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	0.22357655287812228	[154]	[41]	2	hSpCas9	negative selection	390424
57236621	57236644	11	+	26472758	Raji	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	-0.9546261269018254	[308]	[36]	-6	hSpCas9	negative selection	390425
57236477	57236500	11	+	26472758	K562	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-2.1181513517182613	[251]	[48]	-7	hSpCas9	negative selection	581534
57236513	57236536	11	+	26472758	K562	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	0.03058831983342314	[195]	[168]	0	hSpCas9	negative selection	581535
57236366	57236389	11	+	26472758	K562	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-2.2343134469297867	[300]	[53]	-7	hSpCas9	negative selection	581536
57236921	57236944	11	-	26472758	K562	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	-1.200366115006449	[293]	[107]	-6	hSpCas9	negative selection	581537
57236855	57236878	11	+	26472758	K562	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	1.0813179253380663	[144]	[258]	8	hSpCas9	negative selection	581538
57236417	57236440	11	+	26472758	K562	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	-0.6017057645557324	[461]	[256]	-4	hSpCas9	negative selection	581539
57236131	57236154	11	+	26472758	K562	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	1.2444187276664467	[494]	[989]	9	hSpCas9	negative selection	581540
57235986	57236009	11	-	26472758	K562	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	0.35545004005519076	[174]	[188]	2	hSpCas9	negative selection	581541
57236753	57236776	11	+	26472758	K562	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	-0.5705493785010326	[284]	[161]	-4	hSpCas9	negative selection	581542
57236621	57236644	11	+	26472758	K562	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.5299234143039356	[360]	[439]	4	hSpCas9	negative selection	581543
57236302	57236325	11	-	26627737	DLD1	viability	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.6984989286613913	[576]	[249,458,191]	7	hSpCas9	negative selection	779057
57236594	57236617	11	+	26627737	DLD1	viability	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	0.30045023165676144	[120]	[39,58,41]	3	hSpCas9	negative selection	779058
57236734	57236757	11	+	26627737	DLD1	viability	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	0.6042744087171221	[46]	[14,27,23]	6	hSpCas9	negative selection	779059
57236828	57236851	11	+	26627737	DLD1	viability	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.6526590361385052	[1256]	[862,705,331]	6	hSpCas9	negative selection	779060
57236830	57236853	11	-	26627737	DLD1	viability	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	0.2951304608721042	[304]	[89,50,194]	3	hSpCas9	negative selection	779061
57236890	57236913	11	+	26627737	DLD1	viability	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	-0.5314426939500412	[561]	[132,108,121]	-5	hSpCas9	negative selection	779062
57236302	57236325	11	-	26627737	GBM cells	viability after 5 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.06250909300361884	[368]	[237,140]	-1	hSpCas9	negative selection	861372
57236594	57236617	11	+	26627737	GBM cells	viability after 5 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	0.8787359929480553	[71]	[80,60]	9	hSpCas9	negative selection	861373
57236734	57236757	11	+	26627737	GBM cells	viability after 5 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-1.1599798141678828	[49]	[19,3]	-9	hSpCas9	negative selection	861374
57236828	57236851	11	+	26627737	GBM cells	viability after 5 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.3664187940586652	[728]	[475,531]	5	hSpCas9	negative selection	861375
57236830	57236853	11	-	26627737	GBM cells	viability after 5 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	0.06527226130780561	[89]	[39,60]	1	hSpCas9	negative selection	861376
57236890	57236913	11	+	26627737	GBM cells	viability after 5 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.026176060478516283	[346]	[186,191]	0	hSpCas9	negative selection	861377
57236302	57236325	11	-	26627737	GBM cells	viability after 13 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.06775988722556925	[368]	[232,190]	0	hSpCas9	negative selection	943687
57236594	57236617	11	+	26627737	GBM cells	viability after 13 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	0.6552100006352637	[71]	[71,52]	7	hSpCas9	negative selection	943688
57236734	57236757	11	+	26627737	GBM cells	viability after 13 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-1.730274834723109	[49]	[16,0]	-9	hSpCas9	negative selection	943689
57236828	57236851	11	+	26627737	GBM cells	viability after 13 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.5148481743174769	[728]	[616,522]	6	hSpCas9	negative selection	943690
57236830	57236853	11	-	26627737	GBM cells	viability after 13 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	0.9570875609421444	[89]	[112,79]	9	hSpCas9	negative selection	943691
57236890	57236913	11	+	26627737	GBM cells	viability after 13 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.41163924431575216	[346]	[309,201]	5	hSpCas9	negative selection	943692
57236302	57236325	11	-	26627737	GBM cells	viability after 21 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.5551913506101713	[368]	[137,134]	-5	hSpCas9	negative selection	1026002
57236594	57236617	11	+	26627737	GBM cells	viability after 21 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	1.4439639220796723	[71]	[119,93]	9	hSpCas9	negative selection	1026003
57236734	57236757	11	+	26627737	GBM cells	viability after 21 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-0.8397342181986502	[49]	[10,18]	-6	hSpCas9	negative selection	1026004
57236828	57236851	11	+	26627737	GBM cells	viability after 21 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.9484325418973094	[728]	[780,748]	8	hSpCas9	negative selection	1026005
57236830	57236853	11	-	26627737	GBM cells	viability after 21 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	0.480315061458646	[89]	[74,61]	5	hSpCas9	negative selection	1026006
57236890	57236913	11	+	26627737	GBM cells	viability after 21 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	-0.0022653950727161143	[346]	[182,192]	0	hSpCas9	negative selection	1026007
57236302	57236325	11	-	26627737	RPE1	viability after 9 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.10780972640599412	[984]	[338,217]	-1	hSpCas9	negative selection	1108317
57236594	57236617	11	+	26627737	RPE1	viability after 9 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.1617173920443371	[332]	[66,126]	-1	hSpCas9	negative selection	1108318
57236734	57236757	11	+	26627737	RPE1	viability after 9 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	6.524994797833548	[0]	[6,56]	9	hSpCas9	negative selection	1108319
57236828	57236851	11	+	26627737	RPE1	viability after 9 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.03069490458837798	[2879]	[748,1142]	0	hSpCas9	negative selection	1108320
57236830	57236853	11	-	26627737	RPE1	viability after 9 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	8.256381818286934	[1]	[235,133]	9	hSpCas9	negative selection	1108321
57236890	57236913	11	+	26627737	RPE1	viability after 9 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	1.197120440147348	[478]	[321,371]	7	hSpCas9	negative selection	1108322
57236302	57236325	11	-	26627737	RPE1	viability after 12 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.2750897208152507	[984]	[344,293]	1	hSpCas9	negative selection	1190632
57236594	57236617	11	+	26627737	RPE1	viability after 12 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	0.3668752229883825	[332]	[110,119]	2	hSpCas9	negative selection	1190633
57236734	57236757	11	+	26627737	RPE1	viability after 12 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	6.973842714905704	[0]	[8,59]	9	hSpCas9	negative selection	1190634
57236828	57236851	11	+	26627737	RPE1	viability after 12 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.42472241790317855	[2879]	[838,1249]	3	hSpCas9	negative selection	1190635
57236830	57236853	11	-	26627737	RPE1	viability after 12 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	8.491342247848122	[1]	[188,197]	9	hSpCas9	negative selection	1190636
57236890	57236913	11	+	26627737	RPE1	viability after 12 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	1.3526690958578724	[478]	[367,286]	7	hSpCas9	negative selection	1190637
57236302	57236325	11	-	26627737	RPE1	viability after 15 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.8628123758307158	[984]	[634,382]	5	hSpCas9	negative selection	1272947
57236594	57236617	11	+	26627737	RPE1	viability after 15 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.18137148634663247	[332]	[50,113]	-1	hSpCas9	negative selection	1272948
57236734	57236757	11	+	26627737	RPE1	viability after 15 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	7.847226701405191	[0]	[0,126]	9	hSpCas9	negative selection	1272949
57236828	57236851	11	+	26627737	RPE1	viability after 15 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.2646106627936249	[2879]	[1023,934]	1	hSpCas9	negative selection	1272950
57236830	57236853	11	-	26627737	RPE1	viability after 15 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	8.434825786244136	[1]	[151,237]	9	hSpCas9	negative selection	1272951
57236890	57236913	11	+	26627737	RPE1	viability after 15 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.9801879399065505	[478]	[165,364]	6	hSpCas9	negative selection	1272952
57236302	57236325	11	-	26627737	RPE1	viability after 18 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.7925452324652851	[984]	[443,477]	5	hSpCas9	negative selection	1355262
57236594	57236617	11	+	26627737	RPE1	viability after 18 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.27573635160862087	[332]	[80,66]	-2	hSpCas9	negative selection	1355263
57236734	57236757	11	+	26627737	RPE1	viability after 18 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	5.430076380595613	[0]	[0,22]	9	hSpCas9	negative selection	1355264
57236828	57236851	11	+	26627737	RPE1	viability after 18 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.1456183869785177	[2879]	[648,1084]	0	hSpCas9	negative selection	1355265
57236830	57236853	11	-	26627737	RPE1	viability after 18 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	8.843368220958917	[1]	[259,234]	9	hSpCas9	negative selection	1355266
57236890	57236913	11	+	26627737	RPE1	viability after 18 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.659149920267694	[478]	[207,199]	4	hSpCas9	negative selection	1355267
57236302	57236325	11	-	26627737	HeLa	viability after 8 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.42926770714374063	[496]	[186,115,182]	-4	hSpCas9	negative selection	1437577
57236594	57236617	11	+	26627737	HeLa	viability after 8 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.2634455344433613	[176]	[63,101,28]	-3	hSpCas9	negative selection	1437578
57236734	57236757	11	+	26627737	HeLa	viability after 8 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-1.6054974772305495	[82]	[0,31,0]	-9	hSpCas9	negative selection	1437579
57236828	57236851	11	+	26627737	HeLa	viability after 8 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.47275476356421997	[1147]	[865,784,481]	4	hSpCas9	negative selection	1437580
57236830	57236853	11	-	26627737	HeLa	viability after 8 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	1.3920840765887807	[91]	[198,3,130]	8	hSpCas9	negative selection	1437581
57236890	57236913	11	+	26627737	HeLa	viability after 8 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.613234031250619	[511]	[267,406,331]	5	hSpCas9	negative selection	1437582
57236302	57236325	11	-	26627737	HeLa	viability after 12 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.8234818899437357	[496]	[636,83,406]	6	hSpCas9	negative selection	1519892
57236594	57236617	11	+	26627737	HeLa	viability after 12 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	0.4697752156605438	[176]	[199,51,59]	4	hSpCas9	negative selection	1519893
57236734	57236757	11	+	26627737	HeLa	viability after 12 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-1.7437344979265195	[82]	[0,23,3]	-9	hSpCas9	negative selection	1519894
57236828	57236851	11	+	26627737	HeLa	viability after 12 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.34298294497042847	[1147]	[796,402,631]	3	hSpCas9	negative selection	1519895
57236830	57236853	11	-	26627737	HeLa	viability after 12 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	2.1594329184339855	[91]	[204,146,160]	9	hSpCas9	negative selection	1519896
57236890	57236913	11	+	26627737	HeLa	viability after 12 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	-0.07712759219031512	[511]	[142,219,234]	0	hSpCas9	negative selection	1519897
57236302	57236325	11	-	26627737	HeLa	viability after 15 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.17157752695434114	[496]	[110,166,421]	1	hSpCas9	negative selection	1602207
57236594	57236617	11	+	26627737	HeLa	viability after 15 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.7411244835593949	[176]	[31,47,49]	-6	hSpCas9	negative selection	1602208
57236734	57236757	11	+	26627737	HeLa	viability after 15 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-0.4188141104524745	[82]	[2,12,62]	-4	hSpCas9	negative selection	1602209
57236828	57236851	11	+	26627737	HeLa	viability after 15 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	-0.22081611918815502	[1147]	[590,336,261]	-2	hSpCas9	negative selection	1602210
57236830	57236853	11	-	26627737	HeLa	viability after 15 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	1.1491131706454552	[91]	[70,26,156]	7	hSpCas9	negative selection	1602211
57236890	57236913	11	+	26627737	HeLa	viability after 15 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.588839727529338	[511]	[255,289,401]	5	hSpCas9	negative selection	1602212
57236302	57236325	11	-	26627737	HeLa	viability after 18 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.19129056525121713	[496]	[75,143,421]	1	hSpCas9	negative selection	1684522
57236594	57236617	11	+	26627737	HeLa	viability after 18 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.688207557439328	[176]	[25,37,49]	-6	hSpCas9	negative selection	1684523
57236734	57236757	11	+	26627737	HeLa	viability after 18 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-0.3676294572764114	[82]	[1,12,62]	-3	hSpCas9	negative selection	1684524
57236828	57236851	11	+	26627737	HeLa	viability after 18 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	-0.2510506733047224	[1147]	[389,266,261]	-2	hSpCas9	negative selection	1684525
57236830	57236853	11	-	26627737	HeLa	viability after 18 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	1.0132217626160838	[91]	[34,19,156]	7	hSpCas9	negative selection	1684526
57236890	57236913	11	+	26627737	HeLa	viability after 18 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.6228132222173846	[511]	[179,247,401]	5	hSpCas9	negative selection	1684527
57236302	57236325	11	-	26627737	HCT116	viability after 6 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.7733787243984961	[945]	[259,250]	4	hSpCas9	negative selection	1766837
57236594	57236617	11	+	26627737	HCT116	viability after 6 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	1.0085725851762035	[37]	[31,0]	5	hSpCas9	negative selection	1766838
57236734	57236757	11	+	26627737	HCT116	viability after 6 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	7.964098741789607	[0]	[104,2]	9	hSpCas9	negative selection	1766839
57236828	57236851	11	+	26627737	HCT116	viability after 6 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	-1.198849197138525	[1906]	[147,120]	-6	hSpCas9	negative selection	1766840
57236830	57236853	11	-	26627737	HCT116	viability after 6 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	0.07398023012177696	[416]	[175,9]	0	hSpCas9	negative selection	1766841
57236890	57236913	11	+	26627737	HCT116	viability after 6 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	-0.2401793192027549	[740]	[213,34]	-1	hSpCas9	negative selection	1766842
57236302	57236325	11	-	26627737	HCT116	viability after 8 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.06979091466643095	[468]	[266,303,168]	0	hSpCas9	negative selection	1849152
57236594	57236617	11	+	26627737	HCT116	viability after 8 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.561538709598941	[135]	[32,66,51]	-6	hSpCas9	negative selection	1849153
57236734	57236757	11	+	26627737	HCT116	viability after 8 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-2.5487847907565215	[34]	[7,0,0]	-9	hSpCas9	negative selection	1849154
57236828	57236851	11	+	26627737	HCT116	viability after 8 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.44394980064502687	[764]	[415,524,773]	4	hSpCas9	negative selection	1849155
57236830	57236853	11	-	26627737	HCT116	viability after 8 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	-0.9174063042548145	[200]	[22,69,81]	-8	hSpCas9	negative selection	1849156
57236890	57236913	11	+	26627737	HCT116	viability after 8 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.37914880158139797	[276]	[253,182,159]	4	hSpCas9	negative selection	1849157
57236302	57236325	11	-	26627737	HCT116	viability after 9 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	1.5765760119150873	[945]	[801,714]	8	hSpCas9	negative selection	1931467
57236594	57236617	11	+	26627737	HCT116	viability after 9 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	3.490978046238622	[37]	[98,125]	9	hSpCas9	negative selection	1931468
57236734	57236757	11	+	26627737	HCT116	viability after 9 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	1.9049898113534676	[0]	[0,0]	9	hSpCas9	negative selection	1931469
57236828	57236851	11	+	26627737	HCT116	viability after 9 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.30853150822128916	[1906]	[700,574]	2	hSpCas9	negative selection	1931470
57236830	57236853	11	-	26627737	HCT116	viability after 9 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	1.0154449691819492	[416]	[104,319]	7	hSpCas9	negative selection	1931471
57236890	57236913	11	+	26627737	HCT116	viability after 9 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.8171410351433913	[740]	[461,258]	6	hSpCas9	negative selection	1931472
57236302	57236325	11	-	26627737	HCT116	viability after 12 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.1741829156898922	[468]	[271,192,184]	-2	hSpCas9	negative selection	2013782
57236594	57236617	11	+	26627737	HCT116	viability after 12 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.4462683681871784	[135]	[68,55,30]	-5	hSpCas9	negative selection	2013783
57236734	57236757	11	+	26627737	HCT116	viability after 12 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-4.201117921514136	[34]	[0,0,0]	-9	hSpCas9	negative selection	2013784
57236828	57236851	11	+	26627737	HCT116	viability after 12 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.19837147367482055	[764]	[339,604,452]	2	hSpCas9	negative selection	2013785
57236830	57236853	11	-	26627737	HCT116	viability after 12 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	-1.1102400417890181	[200]	[33,85,28]	-8	hSpCas9	negative selection	2013786
57236890	57236913	11	+	26627737	HCT116	viability after 12 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.3398114131876949	[276]	[134,141,278]	3	hSpCas9	negative selection	2013787
57236302	57236325	11	-	26627737	HCT116	viability after 15 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.46086426143640574	[468]	[198,235,152]	-5	hSpCas9	negative selection	2096097
57236594	57236617	11	+	26627737	HCT116	viability after 15 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.1418317013295649	[135]	[92,44,76]	-1	hSpCas9	negative selection	2096098
57236734	57236757	11	+	26627737	HCT116	viability after 15 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-1.8245143037309837	[34]	[4,10,0]	-9	hSpCas9	negative selection	2096099
57236828	57236851	11	+	26627737	HCT116	viability after 15 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.46995813409611853	[764]	[649,689,491]	4	hSpCas9	negative selection	2096100
57236830	57236853	11	-	26627737	HCT116	viability after 15 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	-1.3232030129903039	[200]	[17,72,43]	-8	hSpCas9	negative selection	2096101
57236890	57236913	11	+	26627737	HCT116	viability after 15 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.36230941136533584	[276]	[349,143,137]	3	hSpCas9	negative selection	2096102
57236302	57236325	11	-	26627737	HCT116	viability after 18 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.33109638006280157	[468]	[181,219,133]	-3	hSpCas9	negative selection	2178412
57236594	57236617	11	+	26627737	HCT116	viability after 18 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.41073001972206735	[135]	[45,36,66]	-4	hSpCas9	negative selection	2178413
57236734	57236757	11	+	26627737	HCT116	viability after 18 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-0.3150142484404057	[34]	[3,32,1]	-3	hSpCas9	negative selection	2178414
57236828	57236851	11	+	26627737	HCT116	viability after 18 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.6338511017232529	[764]	[421,735,551]	5	hSpCas9	negative selection	2178415
57236830	57236853	11	-	26627737	HCT116	viability after 18 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	-0.2191120852200713	[200]	[43,171,25]	-2	hSpCas9	negative selection	2178416
57236890	57236913	11	+	26627737	HCT116	viability after 18 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.2541586188012734	[276]	[233,138,104]	2	hSpCas9	negative selection	2178417
57236566	57236589	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGAGGCTGCGGGTCAGCGGGG	APLNR	ENSG00000134817	-1.1224979498415528	[2,2]	[0,0]	-9	hSpCas9	positive selection	2970927
57236478	57236501	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.3982039598920844	[2,2]	[1,0]	-5	hSpCas9	positive selection	2970928
57236736	57236759	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACGTGTAGGTAGCCCACAGGG	APLNR	ENSG00000134817	0.12712384540038568	[4,4]	[3,4]	2	hSpCas9	positive selection	2970929
57236622	57236645	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	-0.7676107224993934	[3,3]	[2,0]	-8	hSpCas9	positive selection	2970930
57236566	57236589	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGAGGCTGCGGGTCAGCGGGG	APLNR	ENSG00000134817	0.27431703821171427	[2,2]	[2,2]	5	hSpCas9	positive selection	3038785
57236478	57236501	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	1.0603958235379853	[2,2]	[4,4]	9	hSpCas9	positive selection	3038786
57236736	57236759	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACGTGTAGGTAGCCCACAGGG	APLNR	ENSG00000134817	0.27007246516960426	[4,4]	[4,3]	5	hSpCas9	positive selection	3038787
57236622	57236645	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.4028872942087959	[3,3]	[4,1]	7	hSpCas9	positive selection	3038788
57236290	57236313		-	24336571	A375	resistance to PLX after 7 days	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.13102544228662194	[30,34]	[34,36]	4	hSpCas9	positive selection	3123300
57236485	57236508		-	24336571	A375	resistance to PLX after 7 days	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-0.07013207899286372	[18,16]	[17,16]	-2	hSpCas9	positive selection	3123311
57236290	57236313		-	24336571	A375	resistance to PLX after 14 days	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.020276416578522527	[36,32]	[16,14]	0	hSpCas9	positive selection	3181093
57236485	57236508		-	24336571	A375	resistance to PLX after 14 days	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-0.37854369305257257	[19,15]	[5,5]	-4	hSpCas9	positive selection	3181104
57236290	57236313		-	24336571	A375	viability after 7 days	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.7824594928669195	[19]	[30,34]	9	hSpCas9	negative selection	3238886
57236485	57236508		-	24336571	A375	viability after 7 days	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.17889059216582803	[16]	[18,16]	2	hSpCas9	negative selection	3238897
57236290	57236313		-	24336571	A375	viability after 14 days	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.896379104527625	[19]	[36,32]	9	hSpCas9	negative selection	3296679
57236485	57236508		-	24336571	A375	viability after 14 days	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.17161808463530182	[16]	[19,15]	2	hSpCas9	negative selection	3296690
57236290	57236313	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	2.9358696625802843	[18,20]	[0,0]	8	hSpCas9	positive selection	3337004
57236050	57236073	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	3.2075132449976773	[25,6]	[0,0]	8	hSpCas9	positive selection	3337005
57236287	57236310	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.5084756481267755	[114,99]	[0,0]	2	hSpCas9	positive selection	3337006
57236316	57236339	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	-1.745488804161219	[512,512]	[0,0]	-9	hSpCas9	positive selection	3356251
57236485	57236508	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	7.257326211445835	[5,5]	[5,5]	9	hSpCas9	positive selection	3356252
57236732	57236755	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.4500329206350477	[208,208]	[0,0]	-3	hSpCas9	positive selection	3356253
57236566	57236589	11	-	26780180	HT29	viability (Avana library 4 designs)	GCTGAGGCTGCGGGTCAGCGGGG	APLNR	ENSG00000134817	0.497514883845375	[]	[]	1	hSpCas9	negative selection	3407033
57236477	57236500	11	+	26780180	HT29	viability (Avana library 4 designs)	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	0.884152828969614	[]	[]	3	hSpCas9	negative selection	3407034
57236735	57236758	11	+	26780180	HT29	viability (Avana library 4 designs)	GTACGTGTAGGTAGCCCACAGGG	APLNR	ENSG00000134817	-0.470802372212232	[]	[]	-7	hSpCas9	negative selection	3407035
57236621	57236644	11	+	26780180	HT29	viability (Avana library 4 designs)	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.46156491474872	[]	[]	1	hSpCas9	negative selection	3407036
57236735	57236758	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTACGTGTAGGTAGCCCACAGGG	APLNR	ENSG00000134817	4.79001946209699	[]	[]	7	hSpCas9	negative selection	3479883
57236621	57236644	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	4.94095560479627	[]	[]	8	hSpCas9	negative selection	3479884
57236477	57236500	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	2.95446064271014	[]	[]	4	hSpCas9	negative selection	3479885
57236566	57236589	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGAGGCTGCGGGTCAGCGGGG	APLNR	ENSG00000134817	4.61032516591423	[]	[]	7	hSpCas9	negative selection	3479886
57236921	57236944	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	-2.22241467172488	[]	[]	-3	hSpCas9	negative selection	3479887
57236788	57236811	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATCTTCATTGCTAGCCTGGCGG	APLNR	ENSG00000134817	1.46388315316087	[]	[]	2	hSpCas9	negative selection	3479888
57236735	57236758	11	+	26780180	A375	viability (Avana lentiGuide)	GTACGTGTAGGTAGCCCACAGGG	APLNR	ENSG00000134817	-0.726386970505952	[]	[]	-1	hSpCas9	negative selection	3588542
57236621	57236644	11	+	26780180	A375	viability (Avana lentiGuide)	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	4.87008635984373	[]	[]	4	hSpCas9	negative selection	3588543
57236477	57236500	11	+	26780180	A375	viability (Avana lentiGuide)	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.197209056265335	[]	[]	0	hSpCas9	negative selection	3588544
57236566	57236589	11	-	26780180	A375	viability (Avana lentiGuide)	GCTGAGGCTGCGGGTCAGCGGGG	APLNR	ENSG00000134817	-0.653090990315703	[]	[]	-1	hSpCas9	negative selection	3588545
57236921	57236944	11	-	26780180	A375	viability (Avana lentiGuide)	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	-5.8260408554362	[]	[]	-8	hSpCas9	negative selection	3588546
57236788	57236811	11	-	26780180	A375	viability (Avana lentiGuide)	TATCTTCATTGCTAGCCTGGCGG	APLNR	ENSG00000134817	-0.199962947916216	[]	[]	0	hSpCas9	negative selection	3588547
57236735	57236758	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACGTGTAGGTAGCCCACAGGG	APLNR	ENSG00000134817	0.2802825175299673	[6]	[8,6]	7	hSpCas9	positive selection	3697201
57236621	57236644	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.1952139421980158	[5]	[6,4]	5	hSpCas9	positive selection	3697202
57236477	57236500	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	0.08118532434391187	[3]	[3,4]	2	hSpCas9	positive selection	3697203
57236566	57236589	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGAGGCTGCGGGTCAGCGGGG	APLNR	ENSG00000134817	0.32299477393099574	[3]	[4,4]	8	hSpCas9	positive selection	3697204
57236921	57236944	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	-0.40791740711130736	[4]	[3,2]	-6	hSpCas9	positive selection	3697205
57236788	57236811	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATCTTCATTGCTAGCCTGGCGG	APLNR	ENSG00000134817	0.06980968689688116	[5]	[6,5]	1	hSpCas9	positive selection	3697206
57236735	57236758	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACGTGTAGGTAGCCCACAGGG	APLNR	ENSG00000134817	0.1623819041160217	[6]	[6,5]	4	hSpCas9	positive selection	3805808
57236621	57236644	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	-0.5334210541945789	[5]	[4,1]	-6	hSpCas9	positive selection	3805809
57236477	57236500	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-1.304948022787662	[4]	[0,0]	-9	hSpCas9	positive selection	3805810
57236566	57236589	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGAGGCTGCGGGTCAGCGGGG	APLNR	ENSG00000134817	0.1804639507288606	[4]	[2,4]	4	hSpCas9	positive selection	3805811
57236921	57236944	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.33712378394837317	[4]	[5,4]	8	hSpCas9	positive selection	3805812
57236788	57236811	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATCTTCATTGCTAGCCTGGCGG	APLNR	ENSG00000134817	0.23704747451115427	[5]	[6,5]	6	hSpCas9	positive selection	3805813
57236290	57236313	11	-	26780180	A375	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.2657763803186	[]	[]	0	hSpCas9	negative selection	3914066
57236287	57236310	11	+	26780180	A375	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.953204092739028	[]	[]	4	hSpCas9	negative selection	3914067
57236485	57236508	11	-	26780180	A375	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.538842126609295	[]	[]	1	hSpCas9	negative selection	3914068
57236732	57236755	11	-	26780180	A375	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	1.7014396615516	[]	[]	9	hSpCas9	negative selection	3914069
57236316	57236339	11	-	26780180	A375	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.953744357491046	[]	[]	4	hSpCas9	negative selection	3914070
57236050	57236073	11	-	26780180	A375	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.495145981126033	[]	[]	1	hSpCas9	negative selection	3914071
57236290	57236313	11	-	26780180	HT29	viability (GeCKOv2 library)	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.204178876765732	[]	[]	0	hSpCas9	negative selection	4022032
57236287	57236310	11	+	26780180	HT29	viability (GeCKOv2 library)	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.995833519418288	[]	[]	4	hSpCas9	negative selection	4022033
57236485	57236508	11	-	26780180	HT29	viability (GeCKOv2 library)	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.633224452596744	[]	[]	2	hSpCas9	negative selection	4022034
57236732	57236755	11	-	26780180	HT29	viability (GeCKOv2 library)	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	1.70489100318964	[]	[]	8	hSpCas9	negative selection	4022035
57236316	57236339	11	-	26780180	HT29	viability (GeCKOv2 library)	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.838542712606442	[]	[]	3	hSpCas9	negative selection	4022036
57236050	57236073	11	-	26780180	HT29	viability (GeCKOv2 library)	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.771298702393032	[]	[]	3	hSpCas9	negative selection	4022037
57236290	57236313	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.27116749202245516	[4]	[3,3]	6	hSpCas9	positive selection	4147227
57236485	57236508	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.18749594553291324	[3]	[3,2]	5	hSpCas9	positive selection	4147238
57236290	57236313	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.7544424251018315	[4]	[3,3,2,3]	5	hSpCas9	positive selection	4211249
57236485	57236508	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.37229215647214003	[3]	[3,1,4,0]	3	hSpCas9	positive selection	4211260
57236290	57236313	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.4442012866610797	[0]	[1,0]	8	hSpCas9	positive selection	4256138
57236050	57236073	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.3522546049254458	[0]	[1,0]	7	hSpCas9	positive selection	4256139
57236287	57236310	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.032473188529724945	[2]	[2,1]	0	hSpCas9	positive selection	4256140
57236316	57236339	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	-0.18860128078169494	[4]	[3,1]	-4	hSpCas9	positive selection	4320422
57236485	57236508	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.1890825105107894	[0]	[0,0]	4	hSpCas9	positive selection	4320423
57236732	57236755	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.698549954345589	[3]	[2,0]	-9	hSpCas9	positive selection	4320424
57236470	57236492	11	-	27760321	OCIAML3	viability	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	0.8419350623397738	[171,131]	[184,245]	8	hSpCas9	negative selection	4378659
57236491	57236513	11	-	27760321	OCIAML3	viability	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	0.09901176462407074	[307,301]	[190,340]	1	hSpCas9	negative selection	4378660
57236720	57236742	11	-	27760321	OCIAML3	viability	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	-0.7921898100230509	[349,318]	[117,193]	-6	hSpCas9	negative selection	4378661
57236791	57236813	11	-	27760321	OCIAML3	viability	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.6198775131371583	[388,334]	[277,636]	7	hSpCas9	negative selection	4378662
57236860	57236882	11	-	27760321	OCIAML3	viability	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.31977088025527833	[766,676]	[653,767]	4	hSpCas9	negative selection	4378663
57236470	57236492	11	-	27760321	OCIAML2	viability	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	0.7729602644660677	[171,131]	[192,228]	9	hSpCas9	negative selection	4462122
57236491	57236513	11	-	27760321	OCIAML2	viability	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	0.7873763928019414	[307,301]	[378,489]	9	hSpCas9	negative selection	4462123
57236720	57236742	11	-	27760321	OCIAML2	viability	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	-0.18662994618903578	[349,318]	[206,277]	-2	hSpCas9	negative selection	4462124
57236791	57236813	11	-	27760321	OCIAML2	viability	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.9295889504073374	[388,334]	[421,732]	9	hSpCas9	negative selection	4462125
57236860	57236882	11	-	27760321	OCIAML2	viability	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.18790113111571827	[766,676]	[503,874]	2	hSpCas9	negative selection	4462126
57236470	57236492	11	-	27760321	MV411	viability	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	1.6222978992899892	[171,131]	[164,518]	9	hSpCas9	negative selection	4545585
57236491	57236513	11	-	27760321	MV411	viability	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	1.3526534588959676	[307,301]	[609,372]	8	hSpCas9	negative selection	4545586
57236720	57236742	11	-	27760321	MV411	viability	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	-0.056396561577740534	[349,318]	[168,276]	0	hSpCas9	negative selection	4545587
57236791	57236813	11	-	27760321	MV411	viability	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	1.167534356567629	[388,334]	[626,396]	8	hSpCas9	negative selection	4545588
57236860	57236882	11	-	27760321	MV411	viability	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.6632835010867244	[766,676]	[705,823]	5	hSpCas9	negative selection	4545589
57236470	57236492	11	-	27760321	HL60	viability	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	0.2655243778503844	[171,131]	[135,160]	3	hSpCas9	negative selection	4629048
57236491	57236513	11	-	27760321	HL60	viability	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	0.3617970286754095	[307,301]	[335,304]	4	hSpCas9	negative selection	4629049
57236720	57236742	11	-	27760321	HL60	viability	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	-0.6724188455566555	[349,318]	[116,228]	-6	hSpCas9	negative selection	4629050
57236791	57236813	11	-	27760321	HL60	viability	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.9505214146537388	[388,334]	[647,486]	8	hSpCas9	negative selection	4629051
57236860	57236882	11	-	27760321	HL60	viability	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.10304829637644108	[766,676]	[525,744]	1	hSpCas9	negative selection	4629052
57236470	57236492	11	-	27760321	HT1080	viability	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	-0.09142221101332093	[131,102]	[31,56]	0	hSpCas9	negative selection	4712511
57236491	57236513	11	-	27760321	HT1080	viability	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	0.49368010084401015	[301,235]	[211,83]	2	hSpCas9	negative selection	4712512
57236720	57236742	11	-	27760321	HT1080	viability	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	-0.16527381467696867	[318,248]	[66,137]	-1	hSpCas9	negative selection	4712513
57236791	57236813	11	-	27760321	HT1080	viability	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.34354970120411865	[334,261]	[32,279]	1	hSpCas9	negative selection	4712514
57236860	57236882	11	-	27760321	HT1080	viability	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.35764436550396306	[676,527]	[265,352]	1	hSpCas9	negative selection	4712515
57236470	57236492	11	-	27760321	HT29	viability after 7 days	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	0.16774640808134267	[131,102]	[218,162,134]	2	hSpCas9	negative selection	4795974
57236491	57236513	11	-	27760321	HT29	viability after 7 days	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	-0.6982225381870796	[301,235]	[330,110,213]	-7	hSpCas9	negative selection	4795975
57236720	57236742	11	-	27760321	HT29	viability after 7 days	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	0.024322564849621087	[318,248]	[591,213,339]	0	hSpCas9	negative selection	4795976
57236791	57236813	11	-	27760321	HT29	viability after 7 days	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	-0.4330629745423586	[334,261]	[319,202,332]	-6	hSpCas9	negative selection	4795977
57236860	57236882	11	-	27760321	HT29	viability after 7 days	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.08328956081497563	[676,527]	[980,630,869]	1	hSpCas9	negative selection	4795978
57236470	57236492	11	-	27760321	HT29	viability after 25 days	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	0.5783201223779264	[131,102]	[224,58,328]	6	hSpCas9	negative selection	4879437
57236491	57236513	11	-	27760321	HT29	viability after 25 days	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	-0.2902438531709197	[301,235]	[176,265,322]	-3	hSpCas9	negative selection	4879438
57236720	57236742	11	-	27760321	HT29	viability after 25 days	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	0.8675104686954213	[318,248]	[485,611,694]	8	hSpCas9	negative selection	4879439
57236791	57236813	11	-	27760321	HT29	viability after 25 days	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.4875944855452113	[334,261]	[526,419,484]	5	hSpCas9	negative selection	4879440
57236860	57236882	11	-	27760321	HT29	viability after 25 days	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.7278447324366021	[676,527]	[1103,1163,1154]	8	hSpCas9	negative selection	4879441
57236470	57236492	11	-	27760321	HT29	viability after 22 days	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	0.5259167582600404	[131,102]	[238,104,241]	6	hSpCas9	negative selection	4962900
57236491	57236513	11	-	27760321	HT29	viability after 22 days	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	-0.08913983951682714	[301,235]	[333,245,295]	-1	hSpCas9	negative selection	4962901
57236720	57236742	11	-	27760321	HT29	viability after 22 days	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	-0.020577185600284098	[318,248]	[364,268,335]	0	hSpCas9	negative selection	4962902
57236791	57236813	11	-	27760321	HT29	viability after 22 days	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.4240157859810729	[334,261]	[498,543,343]	4	hSpCas9	negative selection	4962903
57236860	57236882	11	-	27760321	HT29	viability after 22 days	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.6330899733805248	[676,527]	[1142,887,1208]	7	hSpCas9	negative selection	4962904
57236470	57236492	11	-	27760321	HT29	viability after 19 days	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	0.7719692805496812	[131,102]	[282,104,302]	7	hSpCas9	negative selection	5046363
57236491	57236513	11	-	27760321	HT29	viability after 19 days	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	0.006073470969841177	[301,235]	[332,334,262]	0	hSpCas9	negative selection	5046364
57236720	57236742	11	-	27760321	HT29	viability after 19 days	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	0.927611442292701	[318,248]	[447,520,856]	8	hSpCas9	negative selection	5046365
57236791	57236813	11	-	27760321	HT29	viability after 19 days	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.5717048431999089	[334,261]	[849,497,220]	6	hSpCas9	negative selection	5046366
57236860	57236882	11	-	27760321	HT29	viability after 19 days	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.7186363921181983	[676,527]	[1270,788,1346]	7	hSpCas9	negative selection	5046367
57236470	57236492	11	-	27760321	HT29	viability after 16 days	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	0.11973022236718034	[131,102]	[247,81,109]	1	hSpCas9	negative selection	5129826
57236491	57236513	11	-	27760321	HT29	viability after 16 days	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	-0.08716153508941393	[301,235]	[395,229,235]	-1	hSpCas9	negative selection	5129827
57236720	57236742	11	-	27760321	HT29	viability after 16 days	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	0.03954162168081704	[318,248]	[509,287,199]	0	hSpCas9	negative selection	5129828
57236791	57236813	11	-	27760321	HT29	viability after 16 days	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.2809690152329305	[334,261]	[464,481,273]	3	hSpCas9	negative selection	5129829
57236860	57236882	11	-	27760321	HT29	viability after 16 days	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.8494445516614321	[676,527]	[1331,1230,1090]	8	hSpCas9	negative selection	5129830
57236470	57236492	11	-	27760321	HT29	viability after 13 days	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	1.004945468870857	[131,102]	[515,182,129]	9	hSpCas9	negative selection	5213289
57236491	57236513	11	-	27760321	HT29	viability after 13 days	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	-0.44657788911728447	[301,235]	[221,218,244]	-5	hSpCas9	negative selection	5213290
57236720	57236742	11	-	27760321	HT29	viability after 13 days	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	0.12436148992586113	[318,248]	[417,398,265]	1	hSpCas9	negative selection	5213291
57236791	57236813	11	-	27760321	HT29	viability after 13 days	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.3901378388627357	[334,261]	[437,612,318]	5	hSpCas9	negative selection	5213292
57236860	57236882	11	-	27760321	HT29	viability after 13 days	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.6819009185596158	[676,527]	[1102,1247,1018]	8	hSpCas9	negative selection	5213293
57236470	57236492	11	-	27760321	HT29	viability after 10 days	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	1.016573416231609	[131,102]	[251,309,327]	9	hSpCas9	negative selection	5296752
57236491	57236513	11	-	27760321	HT29	viability after 10 days	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	-0.22339332027193937	[301,235]	[281,308,272]	-3	hSpCas9	negative selection	5296753
57236720	57236742	11	-	27760321	HT29	viability after 10 days	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	-0.5355532472489806	[318,248]	[290,306,139]	-6	hSpCas9	negative selection	5296754
57236791	57236813	11	-	27760321	HT29	viability after 10 days	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	0.277950248918371	[334,261]	[480,383,487]	4	hSpCas9	negative selection	5296755
57236860	57236882	11	-	27760321	HT29	viability after 10 days	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.41865510291294494	[676,527]	[1075,767,1161]	5	hSpCas9	negative selection	5296756
57236470	57236492	11	-	27760321	MOLM13	viability	GACTTGGAGAACACCACTAAGG	APLNR	ENSG00000134817	-0.14452004588948486	[171,131]	[76,76]	-1	hSpCas9	negative selection	5380215
57236491	57236513	11	-	27760321	MOLM13	viability	ATGGTGTTACGCACCACCGGGG	APLNR	ENSG00000134817	1.3485350581525892	[307,301]	[737,184]	8	hSpCas9	negative selection	5380216
57236720	57236742	11	-	27760321	MOLM13	viability	CACGTACCGGGACTATGACTGG	APLNR	ENSG00000134817	2.120971894376272	[349,318]	[1445,287]	9	hSpCas9	negative selection	5380217
57236791	57236813	11	-	27760321	MOLM13	viability	GATATCTTCATTGCTAGCCTGG	APLNR	ENSG00000134817	2.0642885262614707	[388,334]	[390,1243]	9	hSpCas9	negative selection	5380218
57236860	57236882	11	-	27760321	MOLM13	viability	GGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	0.37085014106363046	[766,676]	[447,591]	2	hSpCas9	negative selection	5380219
57236723	57236746	11	+	27661255	K562	viability	GTCATAGTCCCGGTACGTGTAGG	APLNR	ENSG00000134817	-0.007021335703152332	[642,655]	[642,407]	0	dCas9-KRAB	negative selection	5462790
57236735	57236758	11	+	27661255	K562	viability	GTACGTGTAGGTAGCCCACAGGG	APLNR	ENSG00000134817	0.01221998882840103	[1114,1085]	[954,828]	0	dCas9-KRAB	negative selection	5462791
57236860	57236883	11	-	27661255	K562	viability	GGGCACCACGGGCAACGGTCTGG	APLNR	ENSG00000134817	-0.08937580924349925	[570,556]	[468,384]	-3	dCas9-KRAB	negative selection	5462792
57237199	57237222	11	-	27661255	K562	viability	GAGGGTGGAGGAAATTCTGCAGG	APLNR	ENSG00000134817	0.18154492854848603	[640,676]	[644,554]	6	dCas9-KRAB	negative selection	5462793
57236290	57236313	11	-	27260156	BXPC3	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.34695407982138216	[59]	[47,49,147,78]	7	hSpCas9	negative selection	5528598
57236050	57236073	11	-	27260156	BXPC3	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.23650520377661532	[36]	[27,57,16,25]	-5	hSpCas9	negative selection	5528599
57236287	57236310	11	+	27260156	BXPC3	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.2627863325672261	[304]	[282,396,447,414]	6	hSpCas9	negative selection	5528600
57236316	57236339	11	-	27260156	BXPC3	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.3167559468368142	[1043]	[1126,1262,1348,1771]	7	hSpCas9	negative selection	5592882
57236485	57236508	11	-	27260156	BXPC3	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-0.016473855423194905	[40]	[19,48,56,45]	0	hSpCas9	negative selection	5592883
57236732	57236755	11	-	27260156	BXPC3	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.2783523631199639	[555]	[417,497,535,466]	-6	hSpCas9	negative selection	5592884
57236290	57236313	11	-	27260156	A673	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.42904071909380015	[59]	[38,57,47,67]	-8	hSpCas9	negative selection	5649849
57236050	57236073	11	-	27260156	A673	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.4151619518389187	[36]	[40,34,11,46]	-7	hSpCas9	negative selection	5649850
57236287	57236310	11	+	27260156	A673	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.2504485369167538	[304]	[537,331,422,464]	6	hSpCas9	negative selection	5649851
57236316	57236339	11	-	27260156	A673	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.36013757684231895	[1043]	[1733,1378,1527,1824]	8	hSpCas9	negative selection	5714133
57236485	57236508	11	-	27260156	A673	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.6031169131436527	[40]	[63,83,37,113]	9	hSpCas9	negative selection	5714134
57236732	57236755	11	-	27260156	A673	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.12413852473854955	[555]	[667,518,649,620]	-3	hSpCas9	negative selection	5714135
57236290	57236313	11	-	27260156	A375	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	1.0903351884771593	[59]	[149,162,50,224]	9	hSpCas9	negative selection	5771100
57236050	57236073	11	-	27260156	A375	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.7482061364071821	[36]	[180,77,18,19]	9	hSpCas9	negative selection	5771101
57236287	57236310	11	+	27260156	A375	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.10791560038400283	[304]	[426,432,257,418]	1	hSpCas9	negative selection	5771102
57236316	57236339	11	-	27260156	A375	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.3136527086246419	[1043]	[1646,1657,1469,1324]	4	hSpCas9	negative selection	5835384
57236485	57236508	11	-	27260156	A375	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.47468745350507113	[40]	[24,58,117,62]	7	hSpCas9	negative selection	5835385
57236732	57236755	11	-	27260156	A375	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	0.1495992463523393	[555]	[563,738,772,794]	2	hSpCas9	negative selection	5835386
57236290	57236313	11	-	27260156	COLO741	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.13522184169780616	[59]	[42,107,96]	3	hSpCas9	negative selection	5892351
57236050	57236073	11	-	27260156	COLO741	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.6502995376069154	[36]	[170,20,40]	9	hSpCas9	negative selection	5892352
57236287	57236310	11	+	27260156	COLO741	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.03430566693760617	[304]	[430,410,359]	0	hSpCas9	negative selection	5892353
57236316	57236339	11	-	27260156	COLO741	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.08185204911038779	[1043]	[1393,1539,1304]	1	hSpCas9	negative selection	5956635
57236485	57236508	11	-	27260156	COLO741	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.25931561162118166	[40]	[80,66,42]	5	hSpCas9	negative selection	5956636
57236732	57236755	11	-	27260156	COLO741	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.15484445377967837	[555]	[639,703,573]	-3	hSpCas9	negative selection	5956637
57236290	57236313	11	-	27260156	CAL120	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.8198316493998399	[59]	[121,147,123]	9	hSpCas9	negative selection	6013602
57236050	57236073	11	-	27260156	CAL120	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.6572436810531888	[36]	[6,34,41]	-7	hSpCas9	negative selection	6013603
57236287	57236310	11	+	27260156	CAL120	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.8623078777997506	[304]	[1003,260,848]	9	hSpCas9	negative selection	6013604
57236316	57236339	11	-	27260156	CAL120	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.2592921737144871	[1043]	[1895,1741,1085]	4	hSpCas9	negative selection	6077886
57236485	57236508	11	-	27260156	CAL120	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.1340037538217449	[40]	[75,41,52]	2	hSpCas9	negative selection	6077887
57236732	57236755	11	-	27260156	CAL120	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.35217111009300683	[555]	[540,727,359]	-5	hSpCas9	negative selection	6077888
57236290	57236313	11	-	27260156	CADOES1	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.11175271286668842	[59]	[72,38,80,11]	-2	hSpCas9	negative selection	6134853
57236050	57236073	11	-	27260156	CADOES1	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.023008788016840587	[36]	[32,30,23,47]	0	hSpCas9	negative selection	6134854
57236287	57236310	11	+	27260156	CADOES1	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.28148947669205754	[304]	[284,460,327,303]	5	hSpCas9	negative selection	6134855
57236316	57236339	11	-	27260156	CADOES1	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.09471016881911631	[1043]	[943,1048,1109,1044]	1	hSpCas9	negative selection	6199137
57236485	57236508	11	-	27260156	CADOES1	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.6258007537837895	[40]	[28,155,33,14]	8	hSpCas9	negative selection	6199138
57236732	57236755	11	-	27260156	CADOES1	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.3352669211477541	[555]	[476,442,371,344]	-5	hSpCas9	negative selection	6199139
57236290	57236313	11	-	27260156	EWS502	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.03267518638157352	[59]	[34,84,47,83]	0	hSpCas9	negative selection	6256104
57236050	57236073	11	-	27260156	EWS502	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.11080183727866455	[36]	[65,31,32,34]	2	hSpCas9	negative selection	6256105
57236287	57236310	11	+	27260156	EWS502	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.4284950593249659	[304]	[514,469,278,461]	7	hSpCas9	negative selection	6256106
57236316	57236339	11	-	27260156	EWS502	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.2651031878001586	[1043]	[1180,1292,1294,1577]	4	hSpCas9	negative selection	6320388
57236485	57236508	11	-	27260156	EWS502	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.25073639472086784	[40]	[55,68,42,35]	4	hSpCas9	negative selection	6320389
57236732	57236755	11	-	27260156	EWS502	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.06518117340937274	[555]	[508,594,538,614]	-1	hSpCas9	negative selection	6320390
57236290	57236313	11	-	27260156	EW8	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.3237159761115951	[59]	[39,51,41,20]	-6	hSpCas9	negative selection	6377355
57236050	57236073	11	-	27260156	EW8	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.35721296771395883	[36]	[54,20,39,38]	6	hSpCas9	negative selection	6377356
57236287	57236310	11	+	27260156	EW8	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.2533433067993655	[304]	[452,277,110,383]	4	hSpCas9	negative selection	6377357
57236316	57236339	11	-	27260156	EW8	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.1856086985444827	[1043]	[1025,1215,819,816]	3	hSpCas9	negative selection	6441639
57236485	57236508	11	-	27260156	EW8	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.2297593609250672	[40]	[58,17,49,28]	4	hSpCas9	negative selection	6441640
57236732	57236755	11	-	27260156	EW8	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.09809266725773641	[555]	[616,383,225,509]	-2	hSpCas9	negative selection	6441641
57236290	57236313	11	-	27260156	CORL105	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.7590681779282602	[59]	[110,106,122,134]	9	hSpCas9	negative selection	6498606
57236050	57236073	11	-	27260156	CORL105	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.12978677682824014	[36]	[8,25,55,68]	-2	hSpCas9	negative selection	6498607
57236287	57236310	11	+	27260156	CORL105	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.07474812374920059	[304]	[363,345,381,412]	1	hSpCas9	negative selection	6498608
57236316	57236339	11	-	27260156	CORL105	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.021573558323521258	[1043]	[1332,1177,1174,1269]	0	hSpCas9	negative selection	6562890
57236485	57236508	11	-	27260156	CORL105	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.28066944258427773	[40]	[40,63,42,81]	5	hSpCas9	negative selection	6562891
57236732	57236755	11	-	27260156	CORL105	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.24406148721317308	[555]	[488,528,710,492]	-4	hSpCas9	negative selection	6562892
57236290	57236313	11	-	27260156	HS294T	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.18949723420921893	[59]	[15,5,30,30]	-3	hSpCas9	negative selection	6619857
57236050	57236073	11	-	27260156	HS294T	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.7809409021271683	[36]	[6,3,11,10]	-8	hSpCas9	negative selection	6619858
57236287	57236310	11	+	27260156	HS294T	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.25069796051205634	[304]	[212,80,94,171]	3	hSpCas9	negative selection	6619859
57236316	57236339	11	-	27260156	HS294T	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.12394159110646608	[1043]	[589,373,399,369]	1	hSpCas9	negative selection	6684141
57236485	57236508	11	-	27260156	HS294T	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.5711875006511726	[40]	[30,22,17,20]	7	hSpCas9	negative selection	6684142
57236732	57236755	11	-	27260156	HS294T	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.06796287323534572	[555]	[210,172,151,299]	-1	hSpCas9	negative selection	6684143
57236290	57236313	11	-	27260156	HCC44	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.7862049486556764	[59]	[85,58,33,273]	9	hSpCas9	negative selection	6741108
57236050	57236073	11	-	27260156	HCC44	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.5326768568912557	[36]	[6,30,65,15]	-7	hSpCas9	negative selection	6741109
57236287	57236310	11	+	27260156	HCC44	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.29232347234343226	[304]	[409,358,524,417]	5	hSpCas9	negative selection	6741110
57236316	57236339	11	-	27260156	HCC44	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.11267414608308068	[1043]	[1251,1049,1750,1158]	1	hSpCas9	negative selection	6805392
57236485	57236508	11	-	27260156	HCC44	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.6492586471745829	[40]	[29,60,155,55]	9	hSpCas9	negative selection	6805393
57236732	57236755	11	-	27260156	HCC44	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	0.052467631072860677	[555]	[693,423,995,586]	0	hSpCas9	negative selection	6805394
57236290	57236313	11	-	27260156	G402	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.20415128057570442	[59]	[62,104,60,28]	-3	hSpCas9	negative selection	6862359
57236050	57236073	11	-	27260156	G402	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.8939228976243201	[36]	[159,2,167,13]	9	hSpCas9	negative selection	6862360
57236287	57236310	11	+	27260156	G402	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.34081716769354964	[304]	[406,606,415,452]	4	hSpCas9	negative selection	6862361
57236316	57236339	11	-	27260156	G402	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.4397591717758056	[1043]	[1120,2190,1929,1607]	5	hSpCas9	negative selection	6926643
57236485	57236508	11	-	27260156	G402	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	1.7552187268968225	[40]	[48,27,13,539]	9	hSpCas9	negative selection	6926644
57236732	57236755	11	-	27260156	G402	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.05450234671270002	[555]	[731,400,708,759]	0	hSpCas9	negative selection	6926645
57236290	57236313	11	-	27260156	L33	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.27398965771441874	[59]	[48,28,24,38]	-6	hSpCas9	negative selection	6983610
57236050	57236073	11	-	27260156	L33	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.39701603356429294	[36]	[26,3,22,38]	-7	hSpCas9	negative selection	6983611
57236287	57236310	11	+	27260156	L33	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	-0.2174597414999846	[304]	[189,142,181,222]	-5	hSpCas9	negative selection	6983612
57236316	57236339	11	-	27260156	L33	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.031168015993648046	[1043]	[950,457,677,1121]	0	hSpCas9	negative selection	7047894
57236485	57236508	11	-	27260156	L33	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-0.12046595062986043	[40]	[51,4,16,58]	-3	hSpCas9	negative selection	7047895
57236732	57236755	11	-	27260156	L33	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.32497829742409456	[555]	[458,197,284,379]	-6	hSpCas9	negative selection	7047896
57236290	57236313	11	-	27260156	K562	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.5787121734607625	[59]	[55,27,72,147]	7	hSpCas9	negative selection	7104861
57236050	57236073	11	-	27260156	K562	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.04362114932108874	[36]	[7,58,48,12]	0	hSpCas9	negative selection	7104862
57236287	57236310	11	+	27260156	K562	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.4225704356447	[304]	[347,518,513,105]	5	hSpCas9	negative selection	7104863
57236316	57236339	11	-	27260156	K562	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.5084815904578632	[1043]	[1515,1668,1204,953]	6	hSpCas9	negative selection	7169145
57236485	57236508	11	-	27260156	K562	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.09857922785275886	[40]	[62,27,35,30]	1	hSpCas9	negative selection	7169146
57236732	57236755	11	-	27260156	K562	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.21697528259177473	[555]	[667,373,260,411]	-3	hSpCas9	negative selection	7169147
57236290	57236313	11	-	27260156	HT29	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.009864569246227362	[59]	[78,44,82,82]	0	hSpCas9	negative selection	7226112
57236050	57236073	11	-	27260156	HT29	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.22123938660521913	[36]	[30,46,8,63]	-4	hSpCas9	negative selection	7226113
57236287	57236310	11	+	27260156	HT29	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.2737952655131802	[304]	[389,539,404,456]	5	hSpCas9	negative selection	7226114
57236316	57236339	11	-	27260156	HT29	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.22168507414841443	[1043]	[1696,1668,1394,1213]	4	hSpCas9	negative selection	7290396
57236485	57236508	11	-	27260156	HT29	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.6610698445845364	[40]	[159,111,37,20]	9	hSpCas9	negative selection	7290397
57236732	57236755	11	-	27260156	HT29	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.17531866396012105	[555]	[728,710,330,633]	-4	hSpCas9	negative selection	7290398
57236290	57236313	11	-	27260156	MHHES1	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.17794452242054248	[59]	[96,159,44,24]	3	hSpCas9	negative selection	7347363
57236050	57236073	11	-	27260156	MHHES1	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.7738911950172009	[36]	[29,19,16,28]	-8	hSpCas9	negative selection	7347364
57236287	57236310	11	+	27260156	MHHES1	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.1275247936490821	[304]	[275,568,302,355]	2	hSpCas9	negative selection	7347365
57236316	57236339	11	-	27260156	MHHES1	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	-0.044313836242690696	[1043]	[1405,1114,1025,1039]	-1	hSpCas9	negative selection	7411647
57236485	57236508	11	-	27260156	MHHES1	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.43830885053829727	[40]	[62,76,91,26]	7	hSpCas9	negative selection	7411648
57236732	57236755	11	-	27260156	MHHES1	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.26877798565550637	[555]	[766,466,562,337]	-5	hSpCas9	negative selection	7411649
57236290	57236313	11	-	27260156	MEWO	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.6896073777339491	[59]	[86,69,113]	9	hSpCas9	negative selection	7468614
57236050	57236073	11	-	27260156	MEWO	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.34329083167827745	[36]	[73,6,9]	-6	hSpCas9	negative selection	7468615
57236287	57236310	11	+	27260156	MEWO	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.16226909665105066	[304]	[224,442,270]	3	hSpCas9	negative selection	7468616
57236316	57236339	11	-	27260156	MEWO	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.009088229540024972	[1043]	[918,1002,1013]	0	hSpCas9	negative selection	7532898
57236485	57236508	11	-	27260156	MEWO	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-1.2213809993019216	[40]	[29,10,10]	-9	hSpCas9	negative selection	7532899
57236732	57236755	11	-	27260156	MEWO	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.0914190285169563	[555]	[544,403,526]	-2	hSpCas9	negative selection	7532900
57236290	57236313	11	-	27260156	LNCAPCLONEFGC	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.5506727042536754	[59]	[102,29,158,40]	8	hSpCas9	negative selection	7589865
57236050	57236073	11	-	27260156	LNCAPCLONEFGC	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.15608370562449458	[36]	[19,3,37,89]	2	hSpCas9	negative selection	7589866
57236287	57236310	11	+	27260156	LNCAPCLONEFGC	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	-0.08280716598537696	[304]	[247,191,441,192]	-1	hSpCas9	negative selection	7589867
57236316	57236339	11	-	27260156	LNCAPCLONEFGC	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.27567025039072535	[1043]	[1092,917,1551,1091]	4	hSpCas9	negative selection	7654149
57236485	57236508	11	-	27260156	LNCAPCLONEFGC	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.39467064868065904	[40]	[55,54,16,61]	6	hSpCas9	negative selection	7654150
57236732	57236755	11	-	27260156	LNCAPCLONEFGC	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	0.06474197371776036	[555]	[612,473,603,428]	1	hSpCas9	negative selection	7654151
57236290	57236313	11	-	27260156	PANC0327	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.08365186288008042	[59]	[122,27,34,23]	-1	hSpCas9	negative selection	7711116
57236050	57236073	11	-	27260156	PANC0327	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.2947090608769125	[36]	[65,65,6,20]	4	hSpCas9	negative selection	7711117
57236287	57236310	11	+	27260156	PANC0327	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.32438337903298686	[304]	[422,164,272,524]	5	hSpCas9	negative selection	7711118
57236316	57236339	11	-	27260156	PANC0327	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	-0.12418115956322473	[1043]	[671,637,1309,796]	-2	hSpCas9	negative selection	7775400
57236485	57236508	11	-	27260156	PANC0327	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.8316735549012608	[40]	[228,15,27,5]	9	hSpCas9	negative selection	7775401
57236732	57236755	11	-	27260156	PANC0327	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.43692573985615624	[555]	[429,353,342,338]	-6	hSpCas9	negative selection	7775402
57236290	57236313	11	-	27260156	NCIH2009	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.6067212864180256	[59]	[154,80,152]	8	hSpCas9	negative selection	7832367
57236050	57236073	11	-	27260156	NCIH2009	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.8798231331527178	[36]	[25,17,39]	-8	hSpCas9	negative selection	7832368
57236287	57236310	11	+	27260156	NCIH2009	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.6051408807295272	[304]	[902,640,449]	8	hSpCas9	negative selection	7832369
57236316	57236339	11	-	27260156	NCIH2009	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.23298396099316143	[1043]	[1700,1454,1985]	3	hSpCas9	negative selection	7896651
57236485	57236508	11	-	27260156	NCIH2009	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-0.35980338098039333	[40]	[74,35,28]	-5	hSpCas9	negative selection	7896652
57236732	57236755	11	-	27260156	NCIH2009	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.1745906911118223	[555]	[885,618,598]	-2	hSpCas9	negative selection	7896653
57236290	57236313	11	-	27260156	NCIH1373	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	1.1114266931098478	[59]	[328,77,76,34]	9	hSpCas9	negative selection	7953618
57236050	57236073	11	-	27260156	NCIH1373	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.05212772979700819	[36]	[84,32,4,11]	0	hSpCas9	negative selection	7953619
57236287	57236310	11	+	27260156	NCIH1373	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.3492055272338031	[304]	[928,335,281,71]	3	hSpCas9	negative selection	7953620
57236316	57236339	11	-	27260156	NCIH1373	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.0013004287394517977	[1043]	[1808,892,795,348]	0	hSpCas9	negative selection	8017902
57236485	57236508	11	-	27260156	NCIH1373	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-1.2252953004854041	[40]	[3,27,23,4]	-8	hSpCas9	negative selection	8017903
57236732	57236755	11	-	27260156	NCIH1373	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.37795936048674883	[555]	[567,381,173,221]	-4	hSpCas9	negative selection	8017904
57236290	57236313	11	-	27260156	PATU8902	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.6442196665562143	[59]	[60,151,178,115]	6	hSpCas9	negative selection	8074869
57236050	57236073	11	-	27260156	PATU8902	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.05809501298316633	[36]	[81,33,6,89]	0	hSpCas9	negative selection	8074870
57236287	57236310	11	+	27260156	PATU8902	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.4672004016780501	[304]	[228,645,595,914]	5	hSpCas9	negative selection	8074871
57236316	57236339	11	-	27260156	PATU8902	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.6267331947279595	[1043]	[1769,3005,2090,2129]	6	hSpCas9	negative selection	8139153
57236485	57236508	11	-	27260156	PATU8902	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.228528860346088	[40]	[6,117,99,29]	2	hSpCas9	negative selection	8139154
57236732	57236755	11	-	27260156	PATU8902	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	0.604845301044135	[555]	[1619,1284,747,1150]	6	hSpCas9	negative selection	8139155
57236290	57236313	11	-	27260156	PANC1	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.40302104480533796	[59]	[53,14,41,38]	-6	hSpCas9	negative selection	8196120
57236050	57236073	11	-	27260156	PANC1	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.21484855247557144	[36]	[22,8,68,7]	-3	hSpCas9	negative selection	8196121
57236287	57236310	11	+	27260156	PANC1	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.7456846250899775	[304]	[372,495,514,387]	9	hSpCas9	negative selection	8196122
57236316	57236339	11	-	27260156	PANC1	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.5318860755042114	[1043]	[1041,1627,1399,1186]	8	hSpCas9	negative selection	8260404
57236485	57236508	11	-	27260156	PANC1	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.7584191433428451	[40]	[7,124,46,69]	9	hSpCas9	negative selection	8260405
57236732	57236755	11	-	27260156	PANC1	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	0.14698003043654795	[555]	[638,599,435,454]	2	hSpCas9	negative selection	8260406
57236290	57236313	11	-	27260156	PANC0813	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.5020622827292796	[59]	[87,130,63,113]	7	hSpCas9	negative selection	8317371
57236050	57236073	11	-	27260156	PANC0813	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.6595355792957496	[36]	[61,17,20,12]	-7	hSpCas9	negative selection	8317372
57236287	57236310	11	+	27260156	PANC0813	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	-0.02535286763601463	[304]	[462,369,331,257]	0	hSpCas9	negative selection	8317373
57236316	57236339	11	-	27260156	PANC0813	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.3242738358416062	[1043]	[1886,1169,1613,1502]	5	hSpCas9	negative selection	8381655
57236485	57236508	11	-	27260156	PANC0813	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.38718084982070256	[40]	[44,76,44,81]	6	hSpCas9	negative selection	8381656
57236732	57236755	11	-	27260156	PANC0813	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.3563730834980979	[555]	[506,718,467,353]	-5	hSpCas9	negative selection	8381657
57236290	57236313	11	-	27260156	RDES	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.08004401296322161	[59]	[51,51,85,112]	1	hSpCas9	negative selection	8438622
57236050	57236073	11	-	27260156	RDES	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.4763554985313916	[36]	[14,17,67,25]	-7	hSpCas9	negative selection	8438623
57236287	57236310	11	+	27260156	RDES	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.30183227089161235	[304]	[297,402,481,592]	5	hSpCas9	negative selection	8438624
57236316	57236339	11	-	27260156	RDES	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.2496748770898678	[1043]	[1065,1301,1765,1675]	4	hSpCas9	negative selection	8502906
57236485	57236508	11	-	27260156	RDES	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.6054414641375292	[40]	[15,40,79,180]	8	hSpCas9	negative selection	8502907
57236732	57236755	11	-	27260156	RDES	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.1865141947402131	[555]	[416,426,570,915]	-3	hSpCas9	negative selection	8502908
57236290	57236313	11	-	27260156	PC3	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.006711766037971856	[59]	[87,47,38,28]	0	hSpCas9	negative selection	8559873
57236050	57236073	11	-	27260156	PC3	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.38932903897853377	[36]	[9,60,21,20]	-7	hSpCas9	negative selection	8559874
57236287	57236310	11	+	27260156	PC3	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.13383899861260617	[304]	[144,359,574,408]	3	hSpCas9	negative selection	8559875
57236316	57236339	11	-	27260156	PC3	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.16174422822064116	[1043]	[596,1312,1949,1249]	3	hSpCas9	negative selection	8624157
57236485	57236508	11	-	27260156	PC3	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.6518346727717792	[40]	[15,44,222,53]	9	hSpCas9	negative selection	8624158
57236732	57236755	11	-	27260156	PC3	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.07906128598416118	[555]	[319,510,883,565]	-2	hSpCas9	negative selection	8624159
57236290	57236313	11	-	27260156	PATU8988T	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.5796522478751456	[59]	[154,73,41,73]	8	hSpCas9	negative selection	8681124
57236050	57236073	11	-	27260156	PATU8988T	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.47481945272772963	[36]	[0,19,44,36]	-6	hSpCas9	negative selection	8681125
57236287	57236310	11	+	27260156	PATU8988T	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	-0.02822688333670098	[304]	[290,402,234,233]	0	hSpCas9	negative selection	8681126
57236316	57236339	11	-	27260156	PATU8988T	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.6909292456342775	[1043]	[1405,1483,2167,1417]	9	hSpCas9	negative selection	8745408
57236485	57236508	11	-	27260156	PATU8988T	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.13734157040897266	[40]	[12,37,100,18]	2	hSpCas9	negative selection	8745409
57236732	57236755	11	-	27260156	PATU8988T	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.054516719411672965	[555]	[598,569,447,452]	-1	hSpCas9	negative selection	8745410
57236290	57236313	11	-	27260156	T47D	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.1441765556778778	[59]	[60,90,91,62]	3	hSpCas9	negative selection	8802375
57236050	57236073	11	-	27260156	T47D	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.047020723710810675	[36]	[37,25,39,64]	-1	hSpCas9	negative selection	8802376
57236287	57236310	11	+	27260156	T47D	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.2361757904390433	[304]	[466,391,373,444]	5	hSpCas9	negative selection	8802377
57236316	57236339	11	-	27260156	T47D	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.23989037140233993	[1043]	[1368,1401,1490,1485]	5	hSpCas9	negative selection	8866659
57236485	57236508	11	-	27260156	T47D	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.6746584600014591	[40]	[112,63,63,64]	9	hSpCas9	negative selection	8866660
57236732	57236755	11	-	27260156	T47D	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.1748112712773684	[555]	[449,565,503,782]	-4	hSpCas9	negative selection	8866661
57236290	57236313	11	-	27260156	SU8686	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.425181086149363	[59]	[67,92,92,61]	7	hSpCas9	negative selection	8923626
57236050	57236073	11	-	27260156	SU8686	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.2316153350330814	[36]	[23,26,40,34]	-4	hSpCas9	negative selection	8923627
57236287	57236310	11	+	27260156	SU8686	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.1396915766549402	[304]	[391,251,453,220]	2	hSpCas9	negative selection	8923628
57236316	57236339	11	-	27260156	SU8686	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.2322354789394061	[1043]	[1183,858,1220,1722]	4	hSpCas9	negative selection	8987910
57236485	57236508	11	-	27260156	SU8686	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-0.17329450024522908	[40]	[43,21,36,42]	-3	hSpCas9	negative selection	8987911
57236732	57236755	11	-	27260156	SU8686	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.20581668517246332	[555]	[437,462,489,532]	-4	hSpCas9	negative selection	8987912
57236290	57236313	11	-	27260156	SKES1	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.7850195802427384	[59]	[121,69,146,73]	9	hSpCas9	negative selection	9044877
57236050	57236073	11	-	27260156	SKES1	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.28923950159870326	[36]	[72,21,60,26]	6	hSpCas9	negative selection	9044878
57236287	57236310	11	+	27260156	SKES1	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	-0.08958414558000283	[304]	[254,396,329,179]	-2	hSpCas9	negative selection	9044879
57236316	57236339	11	-	27260156	SKES1	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.21770106599883077	[1043]	[1306,1248,1313,1002]	4	hSpCas9	negative selection	9109161
57236485	57236508	11	-	27260156	SKES1	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-0.056770580827862904	[40]	[5,100,23,29]	-1	hSpCas9	negative selection	9109162
57236732	57236755	11	-	27260156	SKES1	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.06930592643454156	[555]	[432,605,570,497]	-1	hSpCas9	negative selection	9109163
57236290	57236313	11	-	27260156	TOV112D	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.18675022579173683	[59]	[54,107,10,106]	3	hSpCas9	negative selection	9166128
57236050	57236073	11	-	27260156	TOV112D	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.5148071214683574	[36]	[41,11,31,112]	8	hSpCas9	negative selection	9166129
57236287	57236310	11	+	27260156	TOV112D	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.24622611186839183	[304]	[301,609,354,240]	5	hSpCas9	negative selection	9166130
57236316	57236339	11	-	27260156	TOV112D	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	-0.07593568363814107	[1043]	[1054,1271,953,765]	-1	hSpCas9	negative selection	9230412
57236485	57236508	11	-	27260156	TOV112D	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.005338189176527841	[40]	[54,57,48,8]	0	hSpCas9	negative selection	9230413
57236732	57236755	11	-	27260156	TOV112D	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	0.059870844918697375	[555]	[651,691,634,380]	1	hSpCas9	negative selection	9230414
57236290	57236313	11	-	27260156	TC71	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	0.04709841853689056	[59]	[61,60,61,81]	1	hSpCas9	negative selection	9287379
57236050	57236073	11	-	27260156	TC71	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	0.22017635996681628	[36]	[39,28,50,65]	5	hSpCas9	negative selection	9287380
57236287	57236310	11	+	27260156	TC71	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.18588164702016663	[304]	[246,499,404,334]	4	hSpCas9	negative selection	9287381
57236316	57236339	11	-	27260156	TC71	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.2123069275833953	[1043]	[1311,1299,1339,1227]	5	hSpCas9	negative selection	9351663
57236485	57236508	11	-	27260156	TC71	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	-0.13602503595231896	[40]	[43,44,22,48]	-4	hSpCas9	negative selection	9351664
57236732	57236755	11	-	27260156	TC71	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.2624012342562403	[555]	[467,466,526,526]	-6	hSpCas9	negative selection	9351665
57236290	57236313	11	-	27260156	TC32	viability	CTTCCGCAAGGAACGCATCGAGG	APLNR	ENSG00000134817	-0.4595168898044051	[59]	[34,0,41,103]	-7	hSpCas9	negative selection	9408630
57236050	57236073	11	-	27260156	TC32	viability	TTTCGACCCCCGCTTCCGCCAGG	APLNR	ENSG00000134817	-0.3220702950279164	[36]	[37,0,25,54]	-5	hSpCas9	negative selection	9408631
57236287	57236310	11	+	27260156	TC32	viability	GGCCCTCGATGCGTTCCTTGCGG	APLNR	ENSG00000134817	0.17287008876940224	[304]	[318,213,430,372]	3	hSpCas9	negative selection	9408632
57236316	57236339	11	-	27260156	TC32	viability	TTCATCGCCCAAACCATCGCTGG	APLNR	ENSG00000134817	0.3932653546861693	[1043]	[1258,877,1657,1519]	6	hSpCas9	negative selection	9472914
57236485	57236508	11	-	27260156	TC32	viability	GTTACGCACCACCGGGGACTTGG	APLNR	ENSG00000134817	0.12968529412162733	[40]	[47,25,55,43]	2	hSpCas9	negative selection	9472915
57236732	57236755	11	-	27260156	TC32	viability	TGTGGGCTACCTACACGTACCGG	APLNR	ENSG00000134817	-0.07958883561698549	[555]	[487,308,754,514]	-1	hSpCas9	negative selection	9472916
57236302	57236325	11	-	27869803	HPAFII	viability after 27 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.12669246884066976	[343]	[329,86,NaN]	1	hSpCas9	negative selection	9542057
57236594	57236617	11	+	27869803	HPAFII	viability after 27 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.022837516773736022	[77]	[17,58,NaN]	0	hSpCas9	negative selection	9542058
57236734	57236757	11	+	27869803	HPAFII	viability after 27 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-4.464736968403057	[41]	[0,0,NaN]	-9	hSpCas9	negative selection	9542059
57236828	57236851	11	+	27869803	HPAFII	viability after 27 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.9690720810265954	[672]	[774,623,NaN]	7	hSpCas9	negative selection	9542060
57236830	57236853	11	-	27869803	HPAFII	viability after 27 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	0.975574735988542	[85]	[143,42,NaN]	7	hSpCas9	negative selection	9542061
57236890	57236913	11	+	27869803	HPAFII	viability after 27 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	-0.18744920757581038	[292]	[143,127,NaN]	-1	hSpCas9	negative selection	9542062
57236302	57236325	11	-	27869803	HPAFII	viability after 15 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.055380458962198564	[343]	[644,221,NaN]	0	hSpCas9	negative selection	9624506
57236594	57236617	11	+	27869803	HPAFII	viability after 15 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.7464382200069395	[77]	[65,39,NaN]	-7	hSpCas9	negative selection	9624507
57236734	57236757	11	+	27869803	HPAFII	viability after 15 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-1.1118854840447026	[41]	[39,8,NaN]	-8	hSpCas9	negative selection	9624508
57236828	57236851	11	+	27869803	HPAFII	viability after 15 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.43673327844363796	[672]	[1364,738,NaN]	5	hSpCas9	negative selection	9624509
57236830	57236853	11	-	27869803	HPAFII	viability after 15 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	0.802212714345526	[85]	[384,21,NaN]	8	hSpCas9	negative selection	9624510
57236890	57236913	11	+	27869803	HPAFII	viability after 15 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	-0.1687564343239195	[292]	[289,273,NaN]	-2	hSpCas9	negative selection	9624511
57236302	57236325	11	-	27869803	ASPC1	viability after 36 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.22932021280497056	[786]	[88,451,378]	2	hSpCas9	negative selection	9706955
57236594	57236617	11	+	27869803	ASPC1	viability after 36 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	0.915905494101587	[243]	[87,326,77]	8	hSpCas9	negative selection	9706956
57236734	57236757	11	+	27869803	ASPC1	viability after 36 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	1.6413912756534756	[36]	[18,0,85]	9	hSpCas9	negative selection	9706957
57236828	57236851	11	+	27869803	ASPC1	viability after 36 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.7664875443977213	[1332]	[588,597,1078]	7	hSpCas9	negative selection	9706958
57236830	57236853	11	-	27869803	ASPC1	viability after 36 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	1.4532558065452177	[213]	[204,215,192]	9	hSpCas9	negative selection	9706959
57236890	57236913	11	+	27869803	ASPC1	viability after 36 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	-0.2464516337354721	[842]	[546,88,161]	-3	hSpCas9	negative selection	9706960
57236302	57236325	11	-	27869803	PATU8988S	viability after 35 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.1415687470633113	[599]	[246,190,NaN]	-1	hSpCas9	negative selection	9789404
57236594	57236617	11	+	27869803	PATU8988S	viability after 35 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	0.3023288215035349	[147]	[74,71,NaN]	3	hSpCas9	negative selection	9789405
57236734	57236757	11	+	27869803	PATU8988S	viability after 35 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	0.12392882831797847	[32]	[6,21,NaN]	1	hSpCas9	negative selection	9789406
57236828	57236851	11	+	27869803	PATU8988S	viability after 35 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	-0.06933607465636826	[1281]	[534,448,NaN]	0	hSpCas9	negative selection	9789407
57236830	57236853	11	-	27869803	PATU8988S	viability after 35 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	-0.6649850012448875	[302]	[61,91,NaN]	-6	hSpCas9	negative selection	9789408
57236890	57236913	11	+	27869803	PATU8988S	viability after 35 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.37253929920678003	[689]	[479,238,NaN]	4	hSpCas9	negative selection	9789409
57236302	57236325	11	-	27869803	PATU8988S	viability after 31 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	0.13611962216649515	[599]	[254,272,NaN]	1	hSpCas9	negative selection	9871853
57236594	57236617	11	+	27869803	PATU8988S	viability after 31 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	0.2577943361476278	[147]	[70,69,NaN]	3	hSpCas9	negative selection	9871854
57236734	57236757	11	+	27869803	PATU8988S	viability after 31 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-0.4018994344607716	[32]	[5,14,NaN]	-4	hSpCas9	negative selection	9871855
57236828	57236851	11	+	27869803	PATU8988S	viability after 31 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	0.11793489376397792	[1281]	[420,724,NaN]	1	hSpCas9	negative selection	9871856
57236830	57236853	11	-	27869803	PATU8988S	viability after 31 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	-0.1343957072131734	[302]	[73,155,NaN]	-1	hSpCas9	negative selection	9871857
57236890	57236913	11	+	27869803	PATU8988S	viability after 31 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	0.2401595513067361	[689]	[353,287,NaN]	3	hSpCas9	negative selection	9871858
57236302	57236325	11	-	27869803	HPAFII	viability after 35 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.09251240092388469	[343]	[239,76,NaN]	0	hSpCas9	negative selection	9954302
57236594	57236617	11	+	27869803	HPAFII	viability after 35 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-1.0422407763650654	[77]	[13,24,NaN]	-5	hSpCas9	negative selection	9954303
57236734	57236757	11	+	27869803	HPAFII	viability after 35 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-4.4102288697820855	[41]	[0,0,NaN]	-9	hSpCas9	negative selection	9954304
57236828	57236851	11	+	27869803	HPAFII	viability after 35 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	1.22309665250047	[672]	[578,1038,NaN]	7	hSpCas9	negative selection	9954305
57236830	57236853	11	-	27869803	HPAFII	viability after 35 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	0.5891162057090812	[85]	[112,11,NaN]	4	hSpCas9	negative selection	9954306
57236890	57236913	11	+	27869803	HPAFII	viability after 35 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	-0.45009258615666425	[292]	[85,133,NaN]	-3	hSpCas9	negative selection	9954307
57236302	57236325	11	-	27869803	HPAFII	viability after 31 days	CATCGCTGGCCACTTCCGCAAGG	APLNR	ENSG00000134817	-0.08957889752561976	[343]	[246,109,NaN]	0	hSpCas9	negative selection	10036751
57236594	57236617	11	+	27869803	HPAFII	viability after 31 days	ATTGGCCACTGGCCTCACGATGG	APLNR	ENSG00000134817	-0.9528684959947762	[77]	[13,31,NaN]	-6	hSpCas9	negative selection	10036752
57236734	57236757	11	+	27869803	HPAFII	viability after 31 days	GGTACGTGTAGGTAGCCCACAGG	APLNR	ENSG00000134817	-4.5589462231035025	[41]	[0,0,NaN]	-9	hSpCas9	negative selection	10036753
57236828	57236851	11	+	27869803	HPAFII	viability after 31 days	CTCCCGGCTGCTCCGAAACACGG	APLNR	ENSG00000134817	1.0093877001479452	[672]	[655,873,NaN]	7	hSpCas9	negative selection	10036754
57236830	57236853	11	-	27869803	HPAFII	viability after 31 days	GACCGTGTTTCGGAGCAGCCGGG	APLNR	ENSG00000134817	0.3134817003222643	[85]	[92,23,NaN]	2	hSpCas9	negative selection	10036755
57236890	57236913	11	+	27869803	HPAFII	viability after 31 days	AGACCAACATGTAGATGGCAGGG	APLNR	ENSG00000134817	-0.5972723296040143	[292]	[112,103,NaN]	-4	hSpCas9	negative selection	10036756
57236477	57236500	11	+	28162770	P31FUJ	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.046612148609282034	[195]	[222]	0	hSpCas9	negative selection	10112021
57236513	57236536	11	+	28162770	P31FUJ	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	0.3935802236867585	[102]	[158]	4	hSpCas9	negative selection	10112022
57236366	57236389	11	+	28162770	P31FUJ	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.8432353926516531	[199]	[130]	-6	hSpCas9	negative selection	10112023
57236921	57236944	11	-	28162770	P31FUJ	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.11827223613250021	[195]	[249]	1	hSpCas9	negative selection	10112024
57236855	57236878	11	+	28162770	P31FUJ	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	-1.2893857327807463	[103]	[49]	-7	hSpCas9	negative selection	10112025
57236417	57236440	11	+	28162770	P31FUJ	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.5496063605129947	[274]	[472]	6	hSpCas9	negative selection	10112026
57236131	57236154	11	+	28162770	P31FUJ	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.3170038508931615	[359]	[526]	3	hSpCas9	negative selection	10112027
57235986	57236009	11	-	28162770	P31FUJ	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	-0.1553234517366614	[144]	[152]	-1	hSpCas9	negative selection	10112028
57236753	57236776	11	+	28162770	P31FUJ	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	0.03143998302272105	[198]	[238]	0	hSpCas9	negative selection	10112029
57236621	57236644	11	+	28162770	P31FUJ	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	1.2373901090607027	[169]	[470]	9	hSpCas9	negative selection	10112030
57236477	57236500	11	+	28162770	TF1	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10281387
57236513	57236536	11	+	28162770	TF1	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10281388
57236366	57236389	11	+	28162770	TF1	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	NaN	[NaN]	[26]	1	hSpCas9	negative selection	10281389
57236921	57236944	11	-	28162770	TF1	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10281390
57236855	57236878	11	+	28162770	TF1	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10281391
57236417	57236440	11	+	28162770	TF1	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10281392
57236131	57236154	11	+	28162770	TF1	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	NaN	[NaN]	[512]	1	hSpCas9	negative selection	10281393
57235986	57236009	11	-	28162770	TF1	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10281394
57236753	57236776	11	+	28162770	TF1	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10281395
57236621	57236644	11	+	28162770	TF1	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10281396
57236477	57236500	11	+	28162770	SKM1	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.7327343599249181	[46]	[49]	-5	hSpCas9	negative selection	10450753
57236513	57236536	11	+	28162770	SKM1	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	0.3155018257279294	[24]	[54]	3	hSpCas9	negative selection	10450754
57236366	57236389	11	+	28162770	SKM1	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.3902854575965314	[42]	[57]	-3	hSpCas9	negative selection	10450755
57236921	57236944	11	-	28162770	SKM1	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.47345418550416574	[54]	[134]	4	hSpCas9	negative selection	10450756
57236855	57236878	11	+	28162770	SKM1	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	0.5168002154297533	[16]	[42]	5	hSpCas9	negative selection	10450757
57236417	57236440	11	+	28162770	SKM1	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.2033093905071819	[112]	[229]	2	hSpCas9	negative selection	10450758
57236131	57236154	11	+	28162770	SKM1	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.21452417800310852	[77]	[159]	2	hSpCas9	negative selection	10450759
57235986	57236009	11	-	28162770	SKM1	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	1.5316352565926952	[26]	[137]	9	hSpCas9	negative selection	10450760
57236753	57236776	11	+	28162770	SKM1	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	-0.10579466402259663	[41]	[68]	-1	hSpCas9	negative selection	10450761
57236621	57236644	11	+	28162770	SKM1	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.16685774437279394	[64]	[128]	1	hSpCas9	negative selection	10450762
57236477	57236500	11	+	28162770	SKM1	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.7327343599249181	[46]	[49]	-5	hSpCas9	negative selection	10620119
57236513	57236536	11	+	28162770	SKM1	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	0.3155018257279294	[24]	[54]	3	hSpCas9	negative selection	10620120
57236366	57236389	11	+	28162770	SKM1	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.3902854575965314	[42]	[57]	-3	hSpCas9	negative selection	10620121
57236921	57236944	11	-	28162770	SKM1	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.47345418550416574	[54]	[134]	4	hSpCas9	negative selection	10620122
57236855	57236878	11	+	28162770	SKM1	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	0.5168002154297533	[16]	[42]	5	hSpCas9	negative selection	10620123
57236417	57236440	11	+	28162770	SKM1	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.2033093905071819	[112]	[229]	2	hSpCas9	negative selection	10620124
57236131	57236154	11	+	28162770	SKM1	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.21452417800310852	[77]	[159]	2	hSpCas9	negative selection	10620125
57235986	57236009	11	-	28162770	SKM1	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	1.5316352565926952	[26]	[137]	9	hSpCas9	negative selection	10620126
57236753	57236776	11	+	28162770	SKM1	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	-0.10579466402259663	[41]	[68]	-1	hSpCas9	negative selection	10620127
57236621	57236644	11	+	28162770	SKM1	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.16685774437279394	[64]	[128]	1	hSpCas9	negative selection	10620128
57236477	57236500	11	+	28162770	PL21	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.4414064145982035	[233]	[74]	-3	hSpCas9	negative selection	10789485
57236513	57236536	11	+	28162770	PL21	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	-0.21489788478952376	[87]	[32]	-1	hSpCas9	negative selection	10789486
57236366	57236389	11	+	28162770	PL21	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.19393826615387752	[204]	[77]	-1	hSpCas9	negative selection	10789487
57236921	57236944	11	-	28162770	PL21	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.36919787211410027	[184]	[103]	3	hSpCas9	negative selection	10789488
57236855	57236878	11	+	28162770	PL21	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	0.7237015705463331	[63]	[45]	6	hSpCas9	negative selection	10789489
57236417	57236440	11	+	28162770	PL21	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	-0.14468888250812095	[380]	[149]	-1	hSpCas9	negative selection	10789490
57236131	57236154	11	+	28162770	PL21	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.5678713989898072	[247]	[159]	5	hSpCas9	negative selection	10789491
57235986	57236009	11	-	28162770	PL21	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	1.313350224937311	[97]	[105]	9	hSpCas9	negative selection	10789492
57236753	57236776	11	+	28162770	PL21	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	0.05878376524377871	[149]	[67]	0	hSpCas9	negative selection	10789493
57236621	57236644	11	+	28162770	PL21	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	-0.1305056974991511	[165]	[65]	-1	hSpCas9	negative selection	10789494
57236477	57236500	11	+	28162770	P31FUJ	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.046612148609282034	[195]	[222]	0	hSpCas9	negative selection	10958851
57236513	57236536	11	+	28162770	P31FUJ	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	0.3935802236867585	[102]	[158]	4	hSpCas9	negative selection	10958852
57236366	57236389	11	+	28162770	P31FUJ	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.8432353926516531	[199]	[130]	-6	hSpCas9	negative selection	10958853
57236921	57236944	11	-	28162770	P31FUJ	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.11827223613250021	[195]	[249]	1	hSpCas9	negative selection	10958854
57236855	57236878	11	+	28162770	P31FUJ	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	-1.2893857327807463	[103]	[49]	-7	hSpCas9	negative selection	10958855
57236417	57236440	11	+	28162770	P31FUJ	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.5496063605129947	[274]	[472]	6	hSpCas9	negative selection	10958856
57236131	57236154	11	+	28162770	P31FUJ	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.3170038508931615	[359]	[526]	3	hSpCas9	negative selection	10958857
57235986	57236009	11	-	28162770	P31FUJ	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	-0.1553234517366614	[144]	[152]	-1	hSpCas9	negative selection	10958858
57236753	57236776	11	+	28162770	P31FUJ	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	0.03143998302272105	[198]	[238]	0	hSpCas9	negative selection	10958859
57236621	57236644	11	+	28162770	P31FUJ	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	1.2373901090607027	[169]	[470]	9	hSpCas9	negative selection	10958860
57236477	57236500	11	+	28162770	OCIAML5	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	0.6959017223749578	[78]	[230]	6	hSpCas9	negative selection	11128217
57236513	57236536	11	+	28162770	OCIAML5	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	1.732895929857159	[21]	[131]	9	hSpCas9	negative selection	11128218
57236366	57236389	11	+	28162770	OCIAML5	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-1.2035389413653748	[147]	[115]	-6	hSpCas9	negative selection	11128219
57236921	57236944	11	-	28162770	OCIAML5	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.3021043592637631	[132]	[295]	2	hSpCas9	negative selection	11128220
57236855	57236878	11	+	28162770	OCIAML5	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	1.9028209312994715	[43]	[296]	9	hSpCas9	negative selection	11128221
57236417	57236440	11	+	28162770	OCIAML5	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.3768746363013889	[156]	[367]	3	hSpCas9	negative selection	11128222
57236131	57236154	11	+	28162770	OCIAML5	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.18223955117332347	[186]	[382]	1	hSpCas9	negative selection	11128223
57235986	57236009	11	-	28162770	OCIAML5	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	0.08184423867823054	[66]	[127]	0	hSpCas9	negative selection	11128224
57236753	57236776	11	+	28162770	OCIAML5	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	-1.562559953669012	[125]	[76]	-7	hSpCas9	negative selection	11128225
57236621	57236644	11	+	28162770	OCIAML5	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.4036946000576191	[115]	[276]	3	hSpCas9	negative selection	11128226
57236477	57236500	11	+	28162770	EOL1	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.22377497538656685	[347]	[156]	-2	hSpCas9	negative selection	11297583
57236513	57236536	11	+	28162770	EOL1	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	-0.9960177609350604	[105]	[27]	-6	hSpCas9	negative selection	11297584
57236366	57236389	11	+	28162770	EOL1	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.7423259269372392	[307]	[96]	-5	hSpCas9	negative selection	11297585
57236921	57236944	11	-	28162770	EOL1	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.15161668011645554	[351]	[205]	1	hSpCas9	negative selection	11297586
57236855	57236878	11	+	28162770	EOL1	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	-1.832475474936925	[168]	[24]	-8	hSpCas9	negative selection	11297587
57236417	57236440	11	+	28162770	EOL1	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.21641366163944165	[610]	[373]	2	hSpCas9	negative selection	11297588
57236131	57236154	11	+	28162770	EOL1	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	-0.11474135954352281	[334]	[162]	-1	hSpCas9	negative selection	11297589
57235986	57236009	11	-	28162770	EOL1	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	-1.502873452164142	[155]	[28]	-7	hSpCas9	negative selection	11297590
57236753	57236776	11	+	28162770	EOL1	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	0.24978860049873242	[173]	[108]	2	hSpCas9	negative selection	11297591
57236621	57236644	11	+	28162770	EOL1	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.0778985484773313	[213]	[118]	0	hSpCas9	negative selection	11297592
57236477	57236500	11	+	28162770	MOLM13	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	0.5559455582097748	[285]	[303]	4	hSpCas9	negative selection	11466949
57236513	57236536	11	+	28162770	MOLM13	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	1.135314042457708	[101]	[161]	8	hSpCas9	negative selection	11466950
57236366	57236389	11	+	28162770	MOLM13	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	0.0951626871236993	[223]	[172]	0	hSpCas9	negative selection	11466951
57236921	57236944	11	-	28162770	MOLM13	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	-0.4285342150128709	[308]	[165]	-3	hSpCas9	negative selection	11466952
57236855	57236878	11	+	28162770	MOLM13	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	-0.16795428817876146	[100]	[64]	-1	hSpCas9	negative selection	11466953
57236417	57236440	11	+	28162770	MOLM13	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	1.5303019887131435	[474]	[991]	9	hSpCas9	negative selection	11466954
57236131	57236154	11	+	28162770	MOLM13	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.23840753542181137	[373]	[318]	1	hSpCas9	negative selection	11466955
57235986	57236009	11	-	28162770	MOLM13	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	-0.23628627750395792	[144]	[88]	-1	hSpCas9	negative selection	11466956
57236753	57236776	11	+	28162770	MOLM13	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	0.6311197304128827	[191]	[214]	5	hSpCas9	negative selection	11466957
57236621	57236644	11	+	28162770	MOLM13	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.13956351545906576	[225]	[179]	1	hSpCas9	negative selection	11466958
57236477	57236500	11	+	28162770	HEL	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	0.5684450496530428	[258]	[245]	5	hSpCas9	negative selection	11636315
57236513	57236536	11	+	28162770	HEL	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	-0.8861896338064714	[100]	[34]	-5	hSpCas9	negative selection	11636316
57236366	57236389	11	+	28162770	HEL	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.05017158208791386	[214]	[132]	0	hSpCas9	negative selection	11636317
57236921	57236944	11	-	28162770	HEL	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.37659851529874155	[278]	[231]	3	hSpCas9	negative selection	11636318
57236855	57236878	11	+	28162770	HEL	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	1.3927605789920097	[65]	[110]	9	hSpCas9	negative selection	11636319
57236417	57236440	11	+	28162770	HEL	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.7813923717863873	[455]	[501]	6	hSpCas9	negative selection	11636320
57236131	57236154	11	+	28162770	HEL	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.0531149539093379	[309]	[205]	0	hSpCas9	negative selection	11636321
57235986	57236009	11	-	28162770	HEL	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	-1.5341389300837227	[103]	[22]	-7	hSpCas9	negative selection	11636322
57236753	57236776	11	+	28162770	HEL	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	0.4598747748505464	[167]	[147]	4	hSpCas9	negative selection	11636323
57236621	57236644	11	+	28162770	HEL	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	1.4706780862140536	[168]	[299]	9	hSpCas9	negative selection	11636324
57236477	57236500	11	+	28162770	MV411	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-1.2489882753367234	[236]	[83]	-7	hSpCas9	negative selection	11805681
57236513	57236536	11	+	28162770	MV411	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	-0.9601578686255919	[96]	[41]	-6	hSpCas9	negative selection	11805682
57236366	57236389	11	+	28162770	MV411	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.06645322503916866	[178]	[143]	0	hSpCas9	negative selection	11805683
57236921	57236944	11	-	28162770	MV411	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.020304096455088794	[253]	[216]	0	hSpCas9	negative selection	11805684
57236855	57236878	11	+	28162770	MV411	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	-0.20154728041940628	[85]	[62]	-1	hSpCas9	negative selection	11805685
57236417	57236440	11	+	28162770	MV411	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.13574467926704803	[348]	[322]	1	hSpCas9	negative selection	11805686
57236131	57236154	11	+	28162770	MV411	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.14456037014247286	[246]	[229]	1	hSpCas9	negative selection	11805687
57235986	57236009	11	-	28162770	MV411	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	0.4945304127475477	[90]	[107]	4	hSpCas9	negative selection	11805688
57236753	57236776	11	+	28162770	MV411	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	-0.09948492357145666	[130]	[102]	-1	hSpCas9	negative selection	11805689
57236621	57236644	11	+	28162770	MV411	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	-0.3199308899236426	[162]	[109]	-2	hSpCas9	negative selection	11805690
57236477	57236500	11	+	28162770	MONOMAC1	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.132496594864843	[152]	[159]	-1	hSpCas9	negative selection	11975047
57236513	57236536	11	+	28162770	MONOMAC1	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	0.8223284778073773	[36]	[74]	7	hSpCas9	negative selection	11975048
57236366	57236389	11	+	28162770	MONOMAC1	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	0.023088967304949137	[90]	[105]	0	hSpCas9	negative selection	11975049
57236921	57236944	11	-	28162770	MONOMAC1	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	-0.6848306887737117	[121]	[86]	-5	hSpCas9	negative selection	11975050
57236855	57236878	11	+	28162770	MONOMAC1	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	0.2180006522192901	[41]	[55]	2	hSpCas9	negative selection	11975051
57236417	57236440	11	+	28162770	MONOMAC1	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.22179223138166426	[189]	[253]	2	hSpCas9	negative selection	11975052
57236131	57236154	11	+	28162770	MONOMAC1	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.17911163882569534	[140]	[182]	1	hSpCas9	negative selection	11975053
57235986	57236009	11	-	28162770	MONOMAC1	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	0.24153616668007927	[75]	[102]	2	hSpCas9	negative selection	11975054
57236753	57236776	11	+	28162770	MONOMAC1	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	1.2153461987733123	[67]	[180]	9	hSpCas9	negative selection	11975055
57236621	57236644	11	+	28162770	MONOMAC1	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.6674997356453276	[105]	[192]	6	hSpCas9	negative selection	11975056
57236477	57236500	11	+	28162770	OCIAML2	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	-0.5131902874702069	[42]	[166]	-4	hSpCas9	negative selection	12144413
57236513	57236536	11	+	28162770	OCIAML2	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	1.381812986343981	[8]	[129]	9	hSpCas9	negative selection	12144414
57236366	57236389	11	+	28162770	OCIAML2	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-1.0921182019884315	[39]	[103]	-6	hSpCas9	negative selection	12144415
57236921	57236944	11	-	28162770	OCIAML2	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	0.6431123408070272	[31]	[276]	6	hSpCas9	negative selection	12144416
57236855	57236878	11	+	28162770	OCIAML2	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	1.2811111216044433	[16]	[228]	9	hSpCas9	negative selection	12144417
57236417	57236440	11	+	28162770	OCIAML2	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	0.6104859092422951	[66]	[566]	6	hSpCas9	negative selection	12144418
57236131	57236154	11	+	28162770	OCIAML2	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	-0.03569276852561265	[53]	[291]	0	hSpCas9	negative selection	12144419
57235986	57236009	11	-	28162770	OCIAML2	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	0.8200473356607613	[13]	[136]	7	hSpCas9	negative selection	12144420
57236753	57236776	11	+	28162770	OCIAML2	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	-0.13720609151696944	[24]	[125]	-1	hSpCas9	negative selection	12144421
57236621	57236644	11	+	28162770	OCIAML2	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	0.3367250968154428	[25]	[181]	3	hSpCas9	negative selection	12144422
57236477	57236500	11	+	28162770	OCIAML3	viability	GGTGTTCTCCAAGTCCCCGGTGG	APLNR	ENSG00000134817	0.534466917624646	[50]	[222]	5	hSpCas9	negative selection	12313779
57236513	57236536	11	+	28162770	OCIAML3	viability	GACAGGCATGGCCAGGAGGGCGG	APLNR	ENSG00000134817	0.33199177823206005	[14]	[56]	3	hSpCas9	negative selection	12313780
57236366	57236389	11	+	28162770	OCIAML3	viability	GGGCACCACAAAGCCCACGGTGG	APLNR	ENSG00000134817	-0.7501268422414449	[38]	[69]	-5	hSpCas9	negative selection	12313781
57236921	57236944	11	-	28162770	OCIAML3	viability	ACACAGACTGGAAATCCTCGGGG	APLNR	ENSG00000134817	-0.6421019285252081	[60]	[117]	-5	hSpCas9	negative selection	12313782
57236855	57236878	11	+	28162770	OCIAML3	viability	GAGCACCAGACCGTTGCCCGTGG	APLNR	ENSG00000134817	0.27106277958972824	[27]	[101]	2	hSpCas9	negative selection	12313783
57236417	57236440	11	+	28162770	OCIAML3	viability	GGCCCACTCTGAGCTCACAGTGG	APLNR	ENSG00000134817	-0.0037701975623328776	[90]	[273]	0	hSpCas9	negative selection	12313784
57236131	57236154	11	+	28162770	OCIAML3	viability	GGAAGATGTTCATGAGGAAGAGG	APLNR	ENSG00000134817	0.061876646327610474	[85]	[270]	0	hSpCas9	negative selection	12313785
57235986	57236009	11	-	28162770	OCIAML3	viability	GGCACCTCCCACAGCAGCAGTGG	APLNR	ENSG00000134817	0.8789282426628818	[28]	[160]	7	hSpCas9	negative selection	12313786
57236753	57236776	11	+	28162770	OCIAML3	viability	CAGGGGCAGCGTCACCACGAAGG	APLNR	ENSG00000134817	1.432271684474686	[33]	[276]	9	hSpCas9	negative selection	12313787
57236621	57236644	11	+	28162770	OCIAML3	viability	GTAGCGGTCGAAGCTGAGGCCGG	APLNR	ENSG00000134817	-0.5008982359326816	[74]	[159]	-4	hSpCas9	negative selection	12313788