Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:333
• Symbol:APLP1
• Description:amyloid beta precursor like protein 1

DataSource: http://genomecrispr.dkfz.de/#!/results/APLP1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
35874778	35874801	19	+	26472758	Jiyoye	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.022812459238941818	[193]	[143]	0	hSpCas9	negative selection	8190
35874577	35874600	19	-	26472758	Jiyoye	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-0.3065204333374856	[40]	[24]	-2	hSpCas9	negative selection	8191
35868653	35868676	19	-	26472758	Jiyoye	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	0.8778052067480347	[69]	[96]	6	hSpCas9	negative selection	8192
35869735	35869758	19	-	26472758	Jiyoye	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-1.3254117721497587	[328]	[98]	-7	hSpCas9	negative selection	8193
35870942	35870965	19	-	26472758	Jiyoye	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	6.914970021704569	[0]	[90]	9	hSpCas9	negative selection	8194
35870997	35871020	19	-	26472758	Jiyoye	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	1.4071753815058736	[14]	[29]	8	hSpCas9	negative selection	8195
35871309	35871332	19	+	26472758	Jiyoye	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.25220072152953255	[215]	[193]	2	hSpCas9	negative selection	8196
35871328	35871351	19	+	26472758	Jiyoye	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	0.5327062635897322	[32]	[35]	4	hSpCas9	negative selection	8197
35872536	35872559	19	+	26472758	Jiyoye	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	0.9921378822270297	[47]	[71]	6	hSpCas9	negative selection	8198
35872565	35872588	19	+	26472758	Jiyoye	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-3.7627496199364394	[53]	[2]	-9	hSpCas9	negative selection	8199
35874778	35874801	19	+	26472758	KBM7	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.5668939789106543	[906,551]	[237,216]	-5	hSpCas9	negative selection	199308
35874577	35874600	19	-	26472758	KBM7	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-0.32724435854932654	[241,147]	[87,56]	-3	hSpCas9	negative selection	199309
35868653	35868676	19	-	26472758	KBM7	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	0.03332646538455897	[328,235]	[137,130]	0	hSpCas9	negative selection	199310
35869735	35869758	19	-	26472758	KBM7	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-0.4437452492291044	[931,520]	[195,288]	-4	hSpCas9	negative selection	199311
35870942	35870965	19	-	26472758	KBM7	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	-0.5521560563693799	[468,271]	[150,84]	-5	hSpCas9	negative selection	199312
35870997	35871020	19	-	26472758	KBM7	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	-0.4530141252557489	[140,97]	[68,14]	-4	hSpCas9	negative selection	199313
35871309	35871332	19	+	26472758	KBM7	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.16163795607203635	[936,569]	[513,275]	1	hSpCas9	negative selection	199314
35871328	35871351	19	+	26472758	KBM7	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-0.5699139611379255	[210,317]	[77,92]	-5	hSpCas9	negative selection	199315
35872536	35872559	19	+	26472758	KBM7	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	0.6285315133419627	[112,121]	[101,71]	7	hSpCas9	negative selection	199316
35872565	35872588	19	+	26472758	KBM7	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	0.5691416894765333	[60,59]	[6,73]	6	hSpCas9	negative selection	199317
35874778	35874801	19	+	26472758	Raji	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-1.297006719705736	[359]	[33]	-7	hSpCas9	negative selection	390426
35874577	35874600	19	-	26472758	Raji	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-0.34327787363596585	[81]	[14]	-3	hSpCas9	negative selection	390427
35868653	35868676	19	-	26472758	Raji	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	0.32977595671004745	[143]	[41]	3	hSpCas9	negative selection	390428
35869735	35869758	19	-	26472758	Raji	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-0.9624134315811708	[486]	[57]	-6	hSpCas9	negative selection	390429
35870942	35870965	19	-	26472758	Raji	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	0.5069909940828373	[93]	[30]	5	hSpCas9	negative selection	390430
35870997	35871020	19	-	26472758	Raji	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	-3.6739761781510603	[54]	[0]	-9	hSpCas9	negative selection	390431
35871309	35871332	19	+	26472758	Raji	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	-0.046944611017694315	[413]	[92]	0	hSpCas9	negative selection	390432
35871328	35871351	19	+	26472758	Raji	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-3.232466467511025	[161]	[3]	-9	hSpCas9	negative selection	390433
35872536	35872559	19	+	26472758	Raji	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	0.07763619197954741	[97]	[23]	0	hSpCas9	negative selection	390434
35872565	35872588	19	+	26472758	Raji	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-3.3188812193284987	[42]	[0]	-9	hSpCas9	negative selection	390435
35874778	35874801	19	+	26472758	K562	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.5893992437187414	[728]	[408]	-4	hSpCas9	negative selection	581544
35874577	35874600	19	-	26472758	K562	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-0.7555812723335531	[115]	[57]	-4	hSpCas9	negative selection	581545
35868653	35868676	19	-	26472758	K562	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-1.145057065198366	[316]	[120]	-6	hSpCas9	negative selection	581546
35869735	35869758	19	-	26472758	K562	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-1.529473435498117	[553]	[161]	-6	hSpCas9	negative selection	581547
35870942	35870965	19	-	26472758	K562	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	0.5296187893027091	[182]	[222]	4	hSpCas9	negative selection	581548
35870997	35871020	19	-	26472758	K562	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	-0.05103715585972446	[107]	[87]	0	hSpCas9	negative selection	581549
35871309	35871332	19	+	26472758	K562	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	-0.5270497138996986	[535]	[313]	-3	hSpCas9	negative selection	581550
35871328	35871351	19	+	26472758	K562	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-1.783925898027515	[256]	[62]	-7	hSpCas9	negative selection	581551
35872536	35872559	19	+	26472758	K562	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	-1.1764243932936025	[82]	[30]	-6	hSpCas9	negative selection	581552
35872565	35872588	19	+	26472758	K562	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-5.31017012401119	[46]	[0]	-9	hSpCas9	negative selection	581553
35868651	35868674	19	-	26627737	DLD1	viability	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	0.023480281765889677	[135]	[83,36,12]	0	hSpCas9	negative selection	804283
35869681	35869704	19	-	26627737	DLD1	viability	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.45740807901286706	[428]	[215,98,226]	5	hSpCas9	negative selection	804284
35871014	35871037	19	-	26627737	DLD1	viability	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.3070839056379985	[204]	[92,86,60]	3	hSpCas9	negative selection	804285
35871319	35871342	19	+	26627737	DLD1	viability	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	-0.22640958690930285	[340]	[137,46,86]	-2	hSpCas9	negative selection	804286
35871661	35871684	19	-	26627737	DLD1	viability	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-1.3481774590408684	[321]	[17,11,80]	-8	hSpCas9	negative selection	804287
35871951	35871974	19	+	26627737	DLD1	viability	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	0.39398798652833955	[227]	[112,107,64]	4	hSpCas9	negative selection	804288
35868651	35868674	19	-	26627737	GBM cells	viability after 5 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	0.4150374992788439	[92]	[69,62]	6	hSpCas9	negative selection	886598
35869681	35869704	19	-	26627737	GBM cells	viability after 5 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.9146239579743473	[136]	[146,129]	9	hSpCas9	negative selection	886599
35871014	35871037	19	-	26627737	GBM cells	viability after 5 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.24221562056561496	[66]	[45,38]	4	hSpCas9	negative selection	886600
35871319	35871342	19	+	26627737	GBM cells	viability after 5 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	-0.5080863053277398	[178]	[67,66]	-7	hSpCas9	negative selection	886601
35871661	35871684	19	-	26627737	GBM cells	viability after 5 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	0.5258704642714689	[157]	[121,121]	7	hSpCas9	negative selection	886602
35871951	35871974	19	+	26627737	GBM cells	viability after 5 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-0.15231144846948785	[85]	[35,46]	-2	hSpCas9	negative selection	886603
35868651	35868674	19	-	26627737	GBM cells	viability after 13 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	0.5334952673382324	[92]	[77,68]	6	hSpCas9	negative selection	968913
35869681	35869704	19	-	26627737	GBM cells	viability after 13 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.4973059137307072	[136]	[94,112]	6	hSpCas9	negative selection	968914
35871014	35871037	19	-	26627737	GBM cells	viability after 13 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.7909345837466693	[66]	[63,61]	8	hSpCas9	negative selection	968915
35871319	35871342	19	+	26627737	GBM cells	viability after 13 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.20639978744453613	[178]	[89,129]	2	hSpCas9	negative selection	968916
35871661	35871684	19	-	26627737	GBM cells	viability after 13 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	0.6631307632057061	[157]	[191,89]	7	hSpCas9	negative selection	968917
35871951	35871974	19	+	26627737	GBM cells	viability after 13 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-0.3642525411087161	[85]	[54,20]	-4	hSpCas9	negative selection	968918
35868651	35868674	19	-	26627737	GBM cells	viability after 21 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	0.2932009347792053	[92]	[63,59]	3	hSpCas9	negative selection	1051228
35869681	35869704	19	-	26627737	GBM cells	viability after 21 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.7811989970657549	[136]	[129,125]	7	hSpCas9	negative selection	1051229
35871014	35871037	19	-	26627737	GBM cells	viability after 21 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.3751986411414976	[66]	[53,40]	4	hSpCas9	negative selection	1051230
35871319	35871342	19	+	26627737	GBM cells	viability after 21 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	-0.7620006586942227	[178]	[60,53]	-6	hSpCas9	negative selection	1051231
35871661	35871684	19	-	26627737	GBM cells	viability after 21 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-1.0266572959928602	[157]	[38,44]	-7	hSpCas9	negative selection	1051232
35871951	35871974	19	+	26627737	GBM cells	viability after 21 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-3.3976396151937687	[85]	[5,2]	-9	hSpCas9	negative selection	1051233
35868651	35868674	19	-	26627737	RPE1	viability after 9 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-0.3050504065263482	[593]	[160,136]	-2	hSpCas9	negative selection	1133543
35869681	35869704	19	-	26627737	RPE1	viability after 9 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	-0.024279396686256973	[803]	[188,322]	0	hSpCas9	negative selection	1133544
35871014	35871037	19	-	26627737	RPE1	viability after 9 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-0.007498864915554737	[141]	[62,19]	0	hSpCas9	negative selection	1133545
35871319	35871342	19	+	26627737	RPE1	viability after 9 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	1.1983020969786466	[318]	[157,320]	7	hSpCas9	negative selection	1133546
35871661	35871684	19	-	26627737	RPE1	viability after 9 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-0.6814520179867167	[613]	[173,49]	-5	hSpCas9	negative selection	1133547
35871951	35871974	19	+	26627737	RPE1	viability after 9 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-1.200627662909721	[531]	[85,54]	-7	hSpCas9	negative selection	1133548
35868651	35868674	19	-	26627737	RPE1	viability after 12 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-0.03545021152094313	[593]	[162,147]	0	hSpCas9	negative selection	1215858
35869681	35869704	19	-	26627737	RPE1	viability after 12 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.4610433295567811	[803]	[359,230]	3	hSpCas9	negative selection	1215859
35871014	35871037	19	-	26627737	RPE1	viability after 12 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.4499712893882313	[141]	[72,29]	3	hSpCas9	negative selection	1215860
35871319	35871342	19	+	26627737	RPE1	viability after 12 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	1.1332876495859057	[318]	[187,187]	6	hSpCas9	negative selection	1215861
35871661	35871684	19	-	26627737	RPE1	viability after 12 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-1.9503020178527708	[613]	[65,17]	-8	hSpCas9	negative selection	1215862
35871951	35871974	19	+	26627737	RPE1	viability after 12 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-1.051841840557267	[531]	[83,52]	-6	hSpCas9	negative selection	1215863
35868651	35868674	19	-	26627737	RPE1	viability after 15 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-0.5831476543167301	[593]	[74,147]	-4	hSpCas9	negative selection	1298173
35869681	35869704	19	-	26627737	RPE1	viability after 15 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.2607616894012164	[803]	[272,271]	1	hSpCas9	negative selection	1298174
35871014	35871037	19	-	26627737	RPE1	viability after 15 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-0.36540316292513886	[141]	[20,40]	-2	hSpCas9	negative selection	1298175
35871319	35871342	19	+	26627737	RPE1	viability after 15 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	-0.28167435534964724	[318]	[32,113]	-2	hSpCas9	negative selection	1298176
35871661	35871684	19	-	26627737	RPE1	viability after 15 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-0.6786142517673872	[613]	[163,54]	-4	hSpCas9	negative selection	1298177
35871951	35871974	19	+	26627737	RPE1	viability after 15 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-1.062838095527342	[531]	[97,46]	-6	hSpCas9	negative selection	1298178
35868651	35868674	19	-	26627737	RPE1	viability after 18 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-0.5851661695054818	[593]	[87,126]	-4	hSpCas9	negative selection	1380488
35869681	35869704	19	-	26627737	RPE1	viability after 18 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.1289456882742355	[803]	[649,286]	6	hSpCas9	negative selection	1380489
35871014	35871037	19	-	26627737	RPE1	viability after 18 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-1.2903070388188107	[141]	[5,25]	-7	hSpCas9	negative selection	1380490
35871319	35871342	19	+	26627737	RPE1	viability after 18 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	1.0954459557639498	[318]	[167,200]	6	hSpCas9	negative selection	1380491
35871661	35871684	19	-	26627737	RPE1	viability after 18 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-1.3967755374544544	[613]	[89,33]	-7	hSpCas9	negative selection	1380492
35871951	35871974	19	+	26627737	RPE1	viability after 18 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-0.9865069364088881	[531]	[114,26]	-6	hSpCas9	negative selection	1380493
35868651	35868674	19	-	26627737	HeLa	viability after 8 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-0.016720692224827527	[101]	[44,44,41]	0	hSpCas9	negative selection	1462803
35869681	35869704	19	-	26627737	HeLa	viability after 8 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.2281378487404044	[186]	[222,209,148]	8	hSpCas9	negative selection	1462804
35871014	35871037	19	-	26627737	HeLa	viability after 8 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	1.2141055024077732	[82]	[184,24,64]	8	hSpCas9	negative selection	1462805
35871319	35871342	19	+	26627737	HeLa	viability after 8 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.5540210525410839	[256]	[249,149,114]	5	hSpCas9	negative selection	1462806
35871661	35871684	19	-	26627737	HeLa	viability after 8 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	0.10373979212540142	[379]	[363,90,122]	1	hSpCas9	negative selection	1462807
35871951	35871974	19	+	26627737	HeLa	viability after 8 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-0.15917367629131118	[176]	[63,30,107]	-1	hSpCas9	negative selection	1462808
35868651	35868674	19	-	26627737	HeLa	viability after 12 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	0.17755925469898148	[101]	[92,31,20]	1	hSpCas9	negative selection	1545118
35869681	35869704	19	-	26627737	HeLa	viability after 12 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.2182495865624892	[186]	[122,35,393]	8	hSpCas9	negative selection	1545119
35871014	35871037	19	-	26627737	HeLa	viability after 12 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	1.9238528398256145	[82]	[91,38,267]	9	hSpCas9	negative selection	1545120
35871319	35871342	19	+	26627737	HeLa	viability after 12 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.21055607185299008	[256]	[256,52,69]	1	hSpCas9	negative selection	1545121
35871661	35871684	19	-	26627737	HeLa	viability after 12 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-0.3065177922982389	[379]	[204,128,48]	-3	hSpCas9	negative selection	1545122
35871951	35871974	19	+	26627737	HeLa	viability after 12 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-1.2885625468554611	[176]	[37,39,10]	-8	hSpCas9	negative selection	1545123
35868651	35868674	19	-	26627737	HeLa	viability after 15 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	0.9408968820356414	[101]	[141,56,35]	7	hSpCas9	negative selection	1627433
35869681	35869704	19	-	26627737	HeLa	viability after 15 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.736468241764849	[186]	[274,71,426]	9	hSpCas9	negative selection	1627434
35871014	35871037	19	-	26627737	HeLa	viability after 15 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.6636113702905384	[82]	[14,32,117]	5	hSpCas9	negative selection	1627435
35871319	35871342	19	+	26627737	HeLa	viability after 15 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.6550770285976817	[256]	[175,190,123]	5	hSpCas9	negative selection	1627436
35871661	35871684	19	-	26627737	HeLa	viability after 15 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	0.10737696829689303	[379]	[143,95,267]	0	hSpCas9	negative selection	1627437
35871951	35871974	19	+	26627737	HeLa	viability after 15 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-1.2548149871437357	[176]	[68,3,15]	-8	hSpCas9	negative selection	1627438
35868651	35868674	19	-	26627737	HeLa	viability after 18 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	0.9331033380085112	[101]	[92,48,35]	7	hSpCas9	negative selection	1709748
35869681	35869704	19	-	26627737	HeLa	viability after 18 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.7092845150244007	[186]	[178,54,426]	9	hSpCas9	negative selection	1709749
35871014	35871037	19	-	26627737	HeLa	viability after 18 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.6395163140286548	[82]	[10,23,117]	5	hSpCas9	negative selection	1709750
35871319	35871342	19	+	26627737	HeLa	viability after 18 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.7123898653808614	[256]	[123,166,123]	5	hSpCas9	negative selection	1709751
35871661	35871684	19	-	26627737	HeLa	viability after 18 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	0.12501854581609642	[379]	[96,83,267]	1	hSpCas9	negative selection	1709752
35871951	35871974	19	+	26627737	HeLa	viability after 18 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-1.4033557735463416	[176]	[39,3,15]	-8	hSpCas9	negative selection	1709753
35868651	35868674	19	-	26627737	HCT116	viability after 6 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	1.4823210818876347	[142]	[134,22]	7	hSpCas9	negative selection	1792063
35869681	35869704	19	-	26627737	HCT116	viability after 6 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	-1.5694692440515632	[986]	[108,20]	-7	hSpCas9	negative selection	1792064
35871014	35871037	19	-	26627737	HCT116	viability after 6 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.7342140035833737	[278]	[32,94]	4	hSpCas9	negative selection	1792065
35871319	35871342	19	+	26627737	HCT116	viability after 6 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	-0.3423477683039798	[439]	[31,66]	-2	hSpCas9	negative selection	1792066
35871661	35871684	19	-	26627737	HCT116	viability after 6 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	0.8417852330261688	[314]	[100,81]	4	hSpCas9	negative selection	1792067
35871951	35871974	19	+	26627737	HCT116	viability after 6 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-1.210536677538676	[191]	[23,6]	-6	hSpCas9	negative selection	1792068
35868651	35868674	19	-	26627737	HCT116	viability after 8 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	1.4209992345474856	[40]	[77,59,43]	9	hSpCas9	negative selection	1874378
35869681	35869704	19	-	26627737	HCT116	viability after 8 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.2836600473996428	[313]	[196,173,259]	3	hSpCas9	negative selection	1874379
35871014	35871037	19	-	26627737	HCT116	viability after 8 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-0.19725943702345494	[164]	[40,98,96]	-2	hSpCas9	negative selection	1874380
35871319	35871342	19	+	26627737	HCT116	viability after 8 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.47458109887329714	[169]	[130,87,170]	5	hSpCas9	negative selection	1874381
35871661	35871684	19	-	26627737	HCT116	viability after 8 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	1.2528603089141508	[87]	[67,93,182]	8	hSpCas9	negative selection	1874382
35871951	35871974	19	+	26627737	HCT116	viability after 8 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-0.31769928851062135	[87]	[40,56,18]	-4	hSpCas9	negative selection	1874383
35868651	35868674	19	-	26627737	HCT116	viability after 9 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	2.3364976168290106	[142]	[136,236]	9	hSpCas9	negative selection	1956693
35869681	35869704	19	-	26627737	HCT116	viability after 9 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.2694943542568642	[986]	[191,416]	2	hSpCas9	negative selection	1956694
35871014	35871037	19	-	26627737	HCT116	viability after 9 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.8310603317844305	[278]	[12,226]	6	hSpCas9	negative selection	1956695
35871319	35871342	19	+	26627737	HCT116	viability after 9 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	-1.9163157732456764	[439]	[48,16]	-8	hSpCas9	negative selection	1956696
35871661	35871684	19	-	26627737	HCT116	viability after 9 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	1.9719070657004187	[314]	[358,306]	9	hSpCas9	negative selection	1956697
35871951	35871974	19	+	26627737	HCT116	viability after 9 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	0.11993604820705372	[191]	[67,45]	0	hSpCas9	negative selection	1956698
35868651	35868674	19	-	26627737	HCT116	viability after 12 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	1.3849104013632074	[40]	[48,78,41]	9	hSpCas9	negative selection	2039008
35869681	35869704	19	-	26627737	HCT116	viability after 12 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.27972094680456083	[313]	[312,114,160]	3	hSpCas9	negative selection	2039009
35871014	35871037	19	-	26627737	HCT116	viability after 12 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-0.25518379689004045	[164]	[46,104,68]	-3	hSpCas9	negative selection	2039010
35871319	35871342	19	+	26627737	HCT116	viability after 12 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.3214995238154946	[169]	[94,136,104]	3	hSpCas9	negative selection	2039011
35871661	35871684	19	-	26627737	HCT116	viability after 12 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	1.2761868817109734	[87]	[131,100,100]	8	hSpCas9	negative selection	2039012
35871951	35871974	19	+	26627737	HCT116	viability after 12 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	1.0287986342587652	[87]	[62,183,40]	8	hSpCas9	negative selection	2039013
35868651	35868674	19	-	26627737	HCT116	viability after 15 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	1.822136005991593	[40]	[64,52,128]	9	hSpCas9	negative selection	2121323
35869681	35869704	19	-	26627737	HCT116	viability after 15 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.2872030782962491	[313]	[211,295,151]	3	hSpCas9	negative selection	2121324
35871014	35871037	19	-	26627737	HCT116	viability after 15 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.4460997592602766	[164]	[101,70,209]	4	hSpCas9	negative selection	2121325
35871319	35871342	19	+	26627737	HCT116	viability after 15 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.6144790221745524	[169]	[144,80,220]	5	hSpCas9	negative selection	2121326
35871661	35871684	19	-	26627737	HCT116	viability after 15 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	0.7144131392139068	[87]	[75,94,76]	6	hSpCas9	negative selection	2121327
35871951	35871974	19	+	26627737	HCT116	viability after 15 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	0.7244528925278209	[87]	[87,157,5]	6	hSpCas9	negative selection	2121328
35868651	35868674	19	-	26627737	HCT116	viability after 18 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	1.1223892970979708	[40]	[25,36,67]	8	hSpCas9	negative selection	2203638
35869681	35869704	19	-	26627737	HCT116	viability after 18 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.38479328105686417	[313]	[89,187,322]	3	hSpCas9	negative selection	2203639
35871014	35871037	19	-	26627737	HCT116	viability after 18 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	0.8787646318463677	[164]	[161,37,251]	7	hSpCas9	negative selection	2203640
35871319	35871342	19	+	26627737	HCT116	viability after 18 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.585702110602682	[169]	[159,99,110]	5	hSpCas9	negative selection	2203641
35871661	35871684	19	-	26627737	HCT116	viability after 18 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	1.0176318586539939	[87]	[50,103,102]	7	hSpCas9	negative selection	2203642
35871951	35871974	19	+	26627737	HCT116	viability after 18 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	0.7730108934620847	[87]	[95,63,57]	6	hSpCas9	negative selection	2203643
35868365	35868388	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGGCGTCCCGCCCCATGAAGG	APLP1	ENSG00000105290	-0.8414305862957338	[34,89]	[10,2]	-5	dCas9-VP64	positive selection	2437339
35868341	35868364	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCCAGGAGTCCGGCTATGG	APLP1	ENSG00000105290	-0.3298604301683259	[164,360]	[35,56]	-1	dCas9-VP64	positive selection	2437340
35868315	35868338	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GACTCAAAATCCACAACGGGCGG	APLP1	ENSG00000105290	0.9812654747736494	[62,260]	[60,81]	4	dCas9-VP64	positive selection	2437341
35868365	35868388	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGGCGTCCCGCCCCATGAAGG	APLP1	ENSG00000105290	2.593725291101954	[39,22]	[96,30]	9	dCas9-VP64	positive selection	2532594
35868341	35868364	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCCAGGAGTCCGGCTATGG	APLP1	ENSG00000105290	0.3316518114934157	[108,85]	[39,38]	2	dCas9-VP64	positive selection	2532595
35868315	35868338	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GACTCAAAATCCACAACGGGCGG	APLP1	ENSG00000105290	0.23725933167050273	[57,27]	[30,2]	2	dCas9-VP64	positive selection	2532596
35871310	35871333	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.02650147241465342	[4,4]	[3,3]	0	hSpCas9	positive selection	2970931
35869654	35869677	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACTTCCATCCAGGCCCCGGGG	APLP1	ENSG00000105290	0.2537677251245267	[3,3]	[3,3]	5	hSpCas9	positive selection	2970932
35871258	35871281	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCCTTCAGGCACCAGCAGGG	APLP1	ENSG00000105290	0.3645503314625316	[2,3]	[3,2]	7	hSpCas9	positive selection	2970933
35869735	35869758	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	0.28702303169022503	[4,4]	[4,5]	6	hSpCas9	positive selection	2970934
35871310	35871333	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	-0.5641737983741713	[4,4]	[3,0]	-7	hSpCas9	positive selection	3038789
35869654	35869677	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACTTCCATCCAGGCCCCGGGG	APLP1	ENSG00000105290	0.09168453045796944	[3,3]	[2,1]	1	hSpCas9	positive selection	3038790
35871258	35871281	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCCTTCAGGCACCAGCAGGG	APLP1	ENSG00000105290	-0.49606572585759484	[2,2]	[2,0]	-7	hSpCas9	positive selection	3038791
35869735	35869758	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	0.0935844153043544	[4,4]	[4,2]	1	hSpCas9	positive selection	3038792
35870902	35870925		-	24336571	A375	resistance to PLX after 7 days	ACACGTGCAATCTGCAGCTCCGG	APLP1	ENSG00000105290	-0.0720233908731027	[15,14]	[13,14]	-2	hSpCas9	positive selection	3123322
35870954	35870977		+	24336571	A375	resistance to PLX after 7 days	AGCGCTGGTGCGGGGGTTCCCGG	APLP1	ENSG00000105290	-0.2538711673092685	[7,6]	[5,5]	-7	hSpCas9	positive selection	3123333
35871940	35871963		-	24336571	A375	resistance to PLX after 7 days	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.40398230646743566	[9,8]	[12,11]	8	hSpCas9	positive selection	3123344
35872011	35872034		-	24336571	A375	resistance to PLX after 7 days	TGCCGACCACTGCAAGTGTATGG	APLP1	ENSG00000105290	-0.10996093020423459	[25,22]	[20,23]	-3	hSpCas9	positive selection	3123355
35870902	35870925		-	24336571	A375	resistance to PLX after 14 days	ACACGTGCAATCTGCAGCTCCGG	APLP1	ENSG00000105290	-0.17830902036103688	[17,12]	[5,5]	-2	hSpCas9	positive selection	3181115
35870954	35870977		+	24336571	A375	resistance to PLX after 14 days	AGCGCTGGTGCGGGGGTTCCCGG	APLP1	ENSG00000105290	0.12914997307899112	[5,6]	[3,2]	1	hSpCas9	positive selection	3181126
35871940	35871963		-	24336571	A375	resistance to PLX after 14 days	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.7618998194203239	[7,8]	[6,5]	6	hSpCas9	positive selection	3181137
35872011	35872034		-	24336571	A375	resistance to PLX after 14 days	TGCCGACCACTGCAAGTGTATGG	APLP1	ENSG00000105290	0.6747809357574905	[24,16]	[15,14]	6	hSpCas9	positive selection	3181148
35870902	35870925		-	24336571	A375	viability after 7 days	ACACGTGCAATCTGCAGCTCCGG	APLP1	ENSG00000105290	0.3953602452461109	[11]	[15,14]	6	hSpCas9	negative selection	3238908
35870954	35870977		+	24336571	A375	viability after 7 days	AGCGCTGGTGCGGGGGTTCCCGG	APLP1	ENSG00000105290	0.35555731659336265	[5]	[7,6]	5	hSpCas9	negative selection	3238919
35871940	35871963		-	24336571	A375	viability after 7 days	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.32236811533551785	[12]	[9,8]	-4	hSpCas9	negative selection	3238930
35872011	35872034		-	24336571	A375	viability after 7 days	TGCCGACCACTGCAAGTGTATGG	APLP1	ENSG00000105290	0.8116900230557998	[13]	[25,22]	9	hSpCas9	negative selection	3238941
35870902	35870925		-	24336571	A375	viability after 14 days	ACACGTGCAATCTGCAGCTCCGG	APLP1	ENSG00000105290	0.44193933909462557	[11]	[17,12]	5	hSpCas9	negative selection	3296701
35870954	35870977		+	24336571	A375	viability after 14 days	AGCGCTGGTGCGGGGGTTCCCGG	APLP1	ENSG00000105290	0.18391031197311047	[5]	[5,6]	2	hSpCas9	negative selection	3296712
35871940	35871963		-	24336571	A375	viability after 14 days	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.4576202206267269	[12]	[7,8]	-5	hSpCas9	negative selection	3296723
35872011	35872034		-	24336571	A375	viability after 14 days	TGCCGACCACTGCAAGTGTATGG	APLP1	ENSG00000105290	0.6174176217410835	[13]	[24,16]	7	hSpCas9	negative selection	3296734
35872592	35872615	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.011012520442316846	[125,177]	[0,0]	0	hSpCas9	positive selection	3337007
35871940	35871963	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	5.732305489211113	[95,119]	[0,73]	9	hSpCas9	positive selection	3337008
35872501	35872524	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.41931703134593035	[99,128]	[0,0]	2	hSpCas9	positive selection	3337009
35871939	35871962	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	0.13838513872232763	[138,138]	[0,0]	0	hSpCas9	positive selection	3356254
35870948	35870971	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3356255
35870931	35870954	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.2662357446111776	[183,183]	[0,0]	-2	hSpCas9	positive selection	3356256
35871309	35871332	19	+	26780180	HT29	viability (Avana library 4 designs)	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	1.73096312213566	[]	[]	6	hSpCas9	negative selection	3407037
35869653	35869676	19	+	26780180	HT29	viability (Avana library 4 designs)	CCACTTCCATCCAGGCCCCGGGG	APLP1	ENSG00000105290	1.75006103335495	[]	[]	6	hSpCas9	negative selection	3407038
35871258	35871281	19	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCCTTCAGGCACCAGCAGGG	APLP1	ENSG00000105290	-0.48058325499843	[]	[]	-7	hSpCas9	negative selection	3407039
35869735	35869758	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	0.924086394181018	[]	[]	3	hSpCas9	negative selection	3407040
35869735	35869758	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	3.61053330199116	[]	[]	6	hSpCas9	negative selection	3479889
35869653	35869676	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACTTCCATCCAGGCCCCGGGG	APLP1	ENSG00000105290	4.53791025446917	[]	[]	7	hSpCas9	negative selection	3479890
35871309	35871332	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	2.68960471394934	[]	[]	4	hSpCas9	negative selection	3479891
35871258	35871281	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCCTTCAGGCACCAGCAGGG	APLP1	ENSG00000105290	5.99650204132192	[]	[]	9	hSpCas9	negative selection	3479892
35869792	35869815	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGAGTACTGCAGACAGGTGG	APLP1	ENSG00000105290	0.119495471005679	[]	[]	0	hSpCas9	negative selection	3479893
35871018	35871041	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGGACTCACGCAGGCAGCGG	APLP1	ENSG00000105290	8.11687412325087	[]	[]	9	hSpCas9	negative selection	3479894
35869735	35869758	19	-	26780180	A375	viability (Avana lentiGuide)	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	7.34417799728796	[]	[]	6	hSpCas9	negative selection	3588548
35869653	35869676	19	+	26780180	A375	viability (Avana lentiGuide)	CCACTTCCATCCAGGCCCCGGGG	APLP1	ENSG00000105290	1.05638503652075	[]	[]	1	hSpCas9	negative selection	3588549
35871309	35871332	19	+	26780180	A375	viability (Avana lentiGuide)	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	1.89268208496825	[]	[]	2	hSpCas9	negative selection	3588550
35871258	35871281	19	-	26780180	A375	viability (Avana lentiGuide)	GCAGCCTTCAGGCACCAGCAGGG	APLP1	ENSG00000105290	-1.05929939164474	[]	[]	-2	hSpCas9	negative selection	3588551
35869792	35869815	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGGAGTACTGCAGACAGGTGG	APLP1	ENSG00000105290	0.696771033766511	[]	[]	0	hSpCas9	negative selection	3588552
35871018	35871041	19	-	26780180	A375	viability (Avana lentiGuide)	CCTGGGACTCACGCAGGCAGCGG	APLP1	ENSG00000105290	-5.9759496659688	[]	[]	-8	hSpCas9	negative selection	3588553
35869735	35869758	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	0.16006605305165517	[5]	[6,5]	4	hSpCas9	positive selection	3697207
35869653	35869676	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACTTCCATCCAGGCCCCGGGG	APLP1	ENSG00000105290	0.04178561108913331	[4]	[4,3]	1	hSpCas9	positive selection	3697208
35871309	35871332	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.1113242566806722	[4]	[4,5]	3	hSpCas9	positive selection	3697209
35871258	35871281	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCCTTCAGGCACCAGCAGGG	APLP1	ENSG00000105290	0.21795174628569275	[4]	[5,4]	6	hSpCas9	positive selection	3697210
35869792	35869815	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGAGTACTGCAGACAGGTGG	APLP1	ENSG00000105290	0.1454541923644407	[4]	[4,4]	4	hSpCas9	positive selection	3697211
35871018	35871041	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGGACTCACGCAGGCAGCGG	APLP1	ENSG00000105290	0.5333906301990277	[3]	[5,5]	9	hSpCas9	positive selection	3697212
35869735	35869758	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-0.30794937381068443	[6]	[3,5]	-4	hSpCas9	positive selection	3805814
35869653	35869676	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACTTCCATCCAGGCCCCGGGG	APLP1	ENSG00000105290	-0.9394324424041339	[5]	[2,0]	-8	hSpCas9	positive selection	3805815
35871309	35871332	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	-0.24882726171336578	[5]	[6,1]	-3	hSpCas9	positive selection	3805816
35871258	35871281	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCCTTCAGGCACCAGCAGGG	APLP1	ENSG00000105290	-0.5438408325414684	[5]	[2,2]	-6	hSpCas9	positive selection	3805817
35869792	35869815	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGAGTACTGCAGACAGGTGG	APLP1	ENSG00000105290	0.05998910384018484	[5]	[4,5]	1	hSpCas9	positive selection	3805818
35871018	35871041	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGGACTCACGCAGGCAGCGG	APLP1	ENSG00000105290	-0.6504380314579754	[3]	[2,0]	-7	hSpCas9	positive selection	3805819
35870948	35870971	19	-	26780180	A375	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.844353931868992	[]	[]	3	hSpCas9	negative selection	3914072
35871939	35871962	19	+	26780180	A375	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	0.865642462020484	[]	[]	3	hSpCas9	negative selection	3914073
35870931	35870954	19	+	26780180	A375	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	1.64332798054424	[]	[]	8	hSpCas9	negative selection	3914074
35872501	35872524	19	-	26780180	A375	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.859534595290594	[]	[]	3	hSpCas9	negative selection	3914075
35872592	35872615	19	+	26780180	A375	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.552247613187803	[]	[]	1	hSpCas9	negative selection	3914076
35871940	35871963	19	-	26780180	A375	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	1.6699006380165	[]	[]	9	hSpCas9	negative selection	3914077
35870948	35870971	19	-	26780180	HT29	viability (GeCKOv2 library)	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.660149977886456	[]	[]	2	hSpCas9	negative selection	4022038
35871939	35871962	19	+	26780180	HT29	viability (GeCKOv2 library)	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	1.03737746822643	[]	[]	5	hSpCas9	negative selection	4022039
35870931	35870954	19	+	26780180	HT29	viability (GeCKOv2 library)	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	1.09621212887568	[]	[]	5	hSpCas9	negative selection	4022040
35872501	35872524	19	-	26780180	HT29	viability (GeCKOv2 library)	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.526740704255653	[]	[]	1	hSpCas9	negative selection	4022041
35872592	35872615	19	+	26780180	HT29	viability (GeCKOv2 library)	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.271547375554302	[]	[]	0	hSpCas9	negative selection	4022042
35871940	35871963	19	-	26780180	HT29	viability (GeCKOv2 library)	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	1.17884933576097	[]	[]	6	hSpCas9	negative selection	4022043
35870902	35870925	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACACGTGCAATCTGCAGCTCCGG	APLP1	ENSG00000105290	0.012828527705200954	[3]	[2,2]	0	hSpCas9	positive selection	4147249
35870954	35870977	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCGCTGGTGCGGGGGTTCCCGG	APLP1	ENSG00000105290	-0.3263911878257846	[3]	[1,1]	-7	hSpCas9	positive selection	4147260
35871940	35871963	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.1345082276783472	[3]	[2,2]	3	hSpCas9	positive selection	4147271
35872011	35872034	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCGACCACTGCAAGTGTATGG	APLP1	ENSG00000105290	0.38326386009149294	[4]	[3,3]	8	hSpCas9	positive selection	4147282
35870902	35870925	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACACGTGCAATCTGCAGCTCCGG	APLP1	ENSG00000105290	0.3394031121331383	[2]	[1,2,2,0]	2	hSpCas9	positive selection	4211271
35870954	35870977	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCGCTGGTGCGGGGGTTCCCGG	APLP1	ENSG00000105290	0.2247985064452276	[2]	[0,2,1,0]	1	hSpCas9	positive selection	4211282
35871940	35871963	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.8598361192683892	[3]	[0,2,0,3]	5	hSpCas9	positive selection	4211293
35872011	35872034	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCGACCACTGCAAGTGTATGG	APLP1	ENSG00000105290	-0.017340300717922807	[4]	[2,3,2,0]	0	hSpCas9	positive selection	4211304
35872592	35872615	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.029040209249951154	[3]	[3,1]	0	hSpCas9	positive selection	4256141
35871940	35871963	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.07259041567775587	[3]	[2,2]	1	hSpCas9	positive selection	4256142
35872501	35872524	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.4585926130135388	[2]	[3,2]	8	hSpCas9	positive selection	4256143
35871939	35871962	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.23849682810297104	[2]	[3,0]	-5	hSpCas9	positive selection	4320425
35870948	35870971	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.07858481916090768	[3]	[2,2]	1	hSpCas9	positive selection	4320426
35870931	35870954	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	0.2843143431192286	[3]	[2,3]	6	hSpCas9	positive selection	4320427
35869713	35869735	19	+	27760321	OCIAML3	viability	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	0.08237668414449567	[692,552]	[527,492]	1	hSpCas9	negative selection	4378664
35869751	35869773	19	-	27760321	OCIAML3	viability	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.9098770475277196	[372,275]	[99,177]	-7	hSpCas9	negative selection	4378665
35871307	35871329	19	-	27760321	OCIAML3	viability	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	0.12387113626368862	[495,315]	[263,440]	1	hSpCas9	negative selection	4378666
35871660	35871682	19	-	27760321	OCIAML3	viability	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.17632254827790994	[477,358]	[318,428]	2	hSpCas9	negative selection	4378667
35871934	35871956	19	-	27760321	OCIAML3	viability	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	0.026828470635120824	[471,426]	[290,444]	0	hSpCas9	negative selection	4378668
35869713	35869735	19	+	27760321	OCIAML2	viability	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	-0.11575083745669573	[692,552]	[429,504]	-1	hSpCas9	negative selection	4462127
35869751	35869773	19	-	27760321	OCIAML2	viability	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.27344797214550765	[372,275]	[222,204]	-3	hSpCas9	negative selection	4462128
35871307	35871329	19	-	27760321	OCIAML2	viability	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	-0.5974573215408293	[495,315]	[237,181]	-6	hSpCas9	negative selection	4462129
35871660	35871682	19	-	27760321	OCIAML2	viability	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.04027575997899832	[477,358]	[292,413]	0	hSpCas9	negative selection	4462130
35871934	35871956	19	-	27760321	OCIAML2	viability	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	0.6481939100683859	[471,426]	[467,702]	8	hSpCas9	negative selection	4462131
35869713	35869735	19	+	27760321	MV411	viability	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	0.0999057699970522	[692,552]	[413,473]	0	hSpCas9	negative selection	4545590
35869751	35869773	19	-	27760321	MV411	viability	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.16094328342726438	[372,275]	[204,166]	-1	hSpCas9	negative selection	4545591
35871307	35871329	19	-	27760321	MV411	viability	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	-0.10757745780587818	[495,315]	[196,316]	-1	hSpCas9	negative selection	4545592
35871660	35871682	19	-	27760321	MV411	viability	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.5324521421209268	[477,358]	[270,583]	4	hSpCas9	negative selection	4545593
35871934	35871956	19	-	27760321	MV411	viability	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	0.6727636034443458	[471,426]	[553,349]	5	hSpCas9	negative selection	4545594
35869713	35869735	19	+	27760321	HL60	viability	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	-0.5851141901709516	[692,552]	[294,381]	-6	hSpCas9	negative selection	4629053
35869751	35869773	19	-	27760321	HL60	viability	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.15419318869003695	[372,275]	[287,180]	-2	hSpCas9	negative selection	4629054
35871307	35871329	19	-	27760321	HL60	viability	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	-0.5936697777470551	[495,315]	[149,286]	-6	hSpCas9	negative selection	4629055
35871660	35871682	19	-	27760321	HL60	viability	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.030218325936481515	[477,358]	[384,304]	0	hSpCas9	negative selection	4629056
35871934	35871956	19	-	27760321	HL60	viability	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	0.11320853453424753	[471,426]	[440,349]	1	hSpCas9	negative selection	4629057
35869713	35869735	19	+	27760321	HT1080	viability	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	0.48099664776760426	[552,431]	[354,184]	2	hSpCas9	negative selection	4712516
35869751	35869773	19	-	27760321	HT1080	viability	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	0.012839137569985337	[275,215]	[64,135]	0	hSpCas9	negative selection	4712517
35871307	35871329	19	-	27760321	HT1080	viability	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	0.6108050735346044	[315,246]	[197,141]	3	hSpCas9	negative selection	4712518
35871660	35871682	19	-	27760321	HT1080	viability	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	-0.4451431313923561	[358,279]	[50,139]	-2	hSpCas9	negative selection	4712519
35871934	35871956	19	-	27760321	HT1080	viability	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	-0.03370531433945926	[426,332]	[60,242]	0	hSpCas9	negative selection	4712520
35869713	35869735	19	+	27760321	HT29	viability after 7 days	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	-0.20912446157403689	[552,431]	[534,405,694]	-3	hSpCas9	negative selection	4795979
35869751	35869773	19	-	27760321	HT29	viability after 7 days	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.17269614947688605	[275,215]	[328,351,170]	-3	hSpCas9	negative selection	4795980
35871307	35871329	19	-	27760321	HT29	viability after 7 days	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	0.37128791559503754	[315,246]	[618,292,511]	5	hSpCas9	negative selection	4795981
35871660	35871682	19	-	27760321	HT29	viability after 7 days	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.18998773110452896	[358,279]	[363,456,565]	3	hSpCas9	negative selection	4795982
35871934	35871956	19	-	27760321	HT29	viability after 7 days	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	-0.5237932158965911	[426,332]	[412,296,319]	-6	hSpCas9	negative selection	4795983
35869713	35869735	19	+	27760321	HT29	viability after 25 days	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	-0.3583633423464453	[552,431]	[285,550,494]	-4	hSpCas9	negative selection	4879442
35869751	35869773	19	-	27760321	HT29	viability after 25 days	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.5834242978433316	[275,215]	[109,248,210]	-5	hSpCas9	negative selection	4879443
35871307	35871329	19	-	27760321	HT29	viability after 25 days	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	-0.5370713620495273	[315,246]	[174,208,290]	-5	hSpCas9	negative selection	4879444
35871660	35871682	19	-	27760321	HT29	viability after 25 days	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.731027798804389	[358,279]	[382,800,651]	8	hSpCas9	negative selection	4879445
35871934	35871956	19	-	27760321	HT29	viability after 25 days	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	0.055302769651221884	[426,332]	[312,499,559]	0	hSpCas9	negative selection	4879446
35869713	35869735	19	+	27760321	HT29	viability after 22 days	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	-0.48919431268912045	[552,431]	[448,438,326]	-4	hSpCas9	negative selection	4962905
35869751	35869773	19	-	27760321	HT29	viability after 22 days	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.39588862259861746	[275,215]	[150,312,185]	-4	hSpCas9	negative selection	4962906
35871307	35871329	19	-	27760321	HT29	viability after 22 days	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	0.054501391314406955	[315,246]	[250,458,305]	0	hSpCas9	negative selection	4962907
35871660	35871682	19	-	27760321	HT29	viability after 22 days	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.6325088417761308	[358,279]	[641,587,484]	7	hSpCas9	negative selection	4962908
35871934	35871956	19	-	27760321	HT29	viability after 22 days	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	0.08149193960483825	[426,332]	[219,612,568]	0	hSpCas9	negative selection	4962909
35869713	35869735	19	+	27760321	HT29	viability after 19 days	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	-0.07669999748830164	[552,431]	[510,591,497]	0	hSpCas9	negative selection	5046368
35869751	35869773	19	-	27760321	HT29	viability after 19 days	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	0.25098916460465176	[275,215]	[108,597,275]	2	hSpCas9	negative selection	5046369
35871307	35871329	19	-	27760321	HT29	viability after 19 days	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	-0.4940085357694703	[315,246]	[257,368,67]	-4	hSpCas9	negative selection	5046370
35871660	35871682	19	-	27760321	HT29	viability after 19 days	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.0602204024438604	[358,279]	[231,646,252]	0	hSpCas9	negative selection	5046371
35871934	35871956	19	-	27760321	HT29	viability after 19 days	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	-0.25703709681294595	[426,332]	[330,196,551]	-2	hSpCas9	negative selection	5046372
35869713	35869735	19	+	27760321	HT29	viability after 16 days	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	-0.06882514726764427	[552,431]	[470,597,499]	0	hSpCas9	negative selection	5129831
35869751	35869773	19	-	27760321	HT29	viability after 16 days	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.09882568670374936	[275,215]	[142,192,425]	-1	hSpCas9	negative selection	5129832
35871307	35871329	19	-	27760321	HT29	viability after 16 days	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	-0.12311218129254414	[315,246]	[240,251,370]	-1	hSpCas9	negative selection	5129833
35871660	35871682	19	-	27760321	HT29	viability after 16 days	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.23184356466812006	[358,279]	[300,380,566]	2	hSpCas9	negative selection	5129834
35871934	35871956	19	-	27760321	HT29	viability after 16 days	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	0.23448223689929312	[426,332]	[375,256,861]	2	hSpCas9	negative selection	5129835
35869713	35869735	19	+	27760321	HT29	viability after 13 days	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	0.1637491277666157	[552,431]	[694,602,622]	2	hSpCas9	negative selection	5213294
35869751	35869773	19	-	27760321	HT29	viability after 13 days	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.18518315204925662	[275,215]	[344,226,184]	-2	hSpCas9	negative selection	5213295
35871307	35871329	19	-	27760321	HT29	viability after 13 days	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	0.45852921566695565	[315,246]	[334,501,505]	6	hSpCas9	negative selection	5213296
35871660	35871682	19	-	27760321	HT29	viability after 13 days	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.3116977164812655	[358,279]	[460,356,555]	4	hSpCas9	negative selection	5213297
35871934	35871956	19	-	27760321	HT29	viability after 13 days	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	0.1067877489315695	[426,332]	[523,563,343]	1	hSpCas9	negative selection	5213298
35869713	35869735	19	+	27760321	HT29	viability after 10 days	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	0.24428438632922195	[552,431]	[668,852,667]	3	hSpCas9	negative selection	5296757
35869751	35869773	19	-	27760321	HT29	viability after 10 days	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.01464253548980421	[275,215]	[208,361,341]	0	hSpCas9	negative selection	5296758
35871307	35871329	19	-	27760321	HT29	viability after 10 days	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	0.4652833884572949	[315,246]	[598,298,550]	6	hSpCas9	negative selection	5296759
35871660	35871682	19	-	27760321	HT29	viability after 10 days	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.41985518568843416	[358,279]	[617,418,559]	6	hSpCas9	negative selection	5296760
35871934	35871956	19	-	27760321	HT29	viability after 10 days	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	-0.11297794104247065	[426,332]	[537,333,440]	-1	hSpCas9	negative selection	5296761
35869713	35869735	19	+	27760321	MOLM13	viability	TTCACCGGGACCTGCGCACCGG	APLP1	ENSG00000105290	-0.4159552593289448	[692,552]	[101,397]	-3	hSpCas9	negative selection	5380220
35869751	35869773	19	-	27760321	MOLM13	viability	GACAGCGTCGAGAGCGCTGTGG	APLP1	ENSG00000105290	-0.2361181162145689	[372,275]	[139,165]	-1	hSpCas9	negative selection	5380221
35871307	35871329	19	-	27760321	MOLM13	viability	CCGGGTTGAACTCTCACATTGG	APLP1	ENSG00000105290	-0.1631012765167528	[495,315]	[180,218]	-1	hSpCas9	negative selection	5380222
35871660	35871682	19	-	27760321	MOLM13	viability	GGAACCGATCCGAGCCACAGGG	APLP1	ENSG00000105290	0.8234640205594635	[477,358]	[624,234]	6	hSpCas9	negative selection	5380223
35871934	35871956	19	-	27760321	MOLM13	viability	AGTAATCATCTACTGGCTGTGG	APLP1	ENSG00000105290	0.2955287249806244	[471,426]	[505,144]	2	hSpCas9	negative selection	5380224
35868566	35868589	19	+	27661255	K562	viability	GGGAGCTCCTGTCACCGCTGGGG	APLP1	ENSG00000105290	-0.1343145449310253	[623,635]	[500,421]	-5	dCas9-KRAB	negative selection	5462794
35868619	35868642	19	+	27661255	K562	viability	GGGCGCAAGGGCCGGGACATGGG	APLP1	ENSG00000105290	0.2486382136407591	[922,1242]	[1152,910]	8	dCas9-KRAB	negative selection	5462795
35868573	35868596	19	-	27661255	K562	viability	GGCCCGGCCCCAGCGGTGACAGG	APLP1	ENSG00000105290	-0.09995702195549316	[453,390]	[352,283]	-4	dCas9-KRAB	negative selection	5462796
35868630	35868653	19	-	27661255	K562	viability	GGCTGGCGGGCCCCATGTCCCGG	APLP1	ENSG00000105290	0.1302908010010749	[672,665]	[646,532]	4	dCas9-KRAB	negative selection	5462797
35868948	35868971	19	-	27661255	K562	viability	GCTGGGACGTCGCATGATGGGGG	APLP1	ENSG00000105290	0.3644291586259756	[211,346]	[285,283]	9	dCas9-KRAB	negative selection	5462798
35869010	35869033	19	-	27661255	K562	viability	GGCTGGACTTCTGGGACCAGGGG	APLP1	ENSG00000105290	0.2419718255955967	[391,519]	[494,371]	7	dCas9-KRAB	negative selection	5462799
35872592	35872615	19	+	27260156	BXPC3	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.1876245733789147	[661]	[768,702,819,873]	4	hSpCas9	negative selection	5528601
35871940	35871963	19	-	27260156	BXPC3	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.017208806359039708	[559]	[493,620,555,654]	0	hSpCas9	negative selection	5528602
35872501	35872524	19	-	27260156	BXPC3	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.43605743735789976	[343]	[424,470,446,623]	8	hSpCas9	negative selection	5528603
35871939	35871962	19	+	27260156	BXPC3	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.04676515041417435	[430]	[339,422,452,551]	-1	hSpCas9	negative selection	5592885
35870948	35870971	19	-	27260156	BXPC3	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.026090065513382443	[633]	[656,646,642,761]	0	hSpCas9	negative selection	5592886
35870931	35870954	19	+	27260156	BXPC3	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.05112737525982425	[589]	[599,531,585,671]	-1	hSpCas9	negative selection	5592887
35872592	35872615	19	+	27260156	A673	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.00999377645826266	[661]	[955,849,733,624]	0	hSpCas9	negative selection	5649852
35871940	35871963	19	-	27260156	A673	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.04379072318737509	[559]	[741,617,673,580]	-1	hSpCas9	negative selection	5649853
35872501	35872524	19	-	27260156	A673	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.188245492733143	[343]	[564,446,477,398]	4	hSpCas9	negative selection	5649854
35871939	35871962	19	+	27260156	A673	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.22906894914401438	[430]	[395,454,472,434]	-5	hSpCas9	negative selection	5714136
35870948	35870971	19	-	27260156	A673	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.050908345993461834	[633]	[712,756,699,766]	-1	hSpCas9	negative selection	5714137
35870931	35870954	19	+	27260156	A673	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.11481961982368591	[589]	[723,672,556,670]	-3	hSpCas9	negative selection	5714138
35872592	35872615	19	+	27260156	A375	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.06713917889220389	[661]	[990,860,671,730]	1	hSpCas9	negative selection	5771103
35871940	35871963	19	-	27260156	A375	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.26515320775043844	[559]	[497,647,470,568]	-4	hSpCas9	negative selection	5771104
35872501	35872524	19	-	27260156	A375	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.34798123303390854	[343]	[558,548,483,462]	5	hSpCas9	negative selection	5771105
35871939	35871962	19	+	27260156	A375	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	0.08241524127009585	[430]	[575,487,554,507]	1	hSpCas9	negative selection	5835387
35870948	35870971	19	-	27260156	A375	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.10506444827243733	[633]	[706,995,474,623]	-1	hSpCas9	negative selection	5835388
35870931	35870954	19	+	27260156	A375	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.6934391275580547	[589]	[499,534,390,306]	-7	hSpCas9	negative selection	5835389
35872592	35872615	19	+	27260156	COLO741	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.09714898024886998	[661]	[1038,913,779]	2	hSpCas9	negative selection	5892354
35871940	35871963	19	-	27260156	COLO741	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.18269302807220617	[559]	[868,513,533]	-4	hSpCas9	negative selection	5892355
35872501	35872524	19	-	27260156	COLO741	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.5753157774111156	[343]	[801,693,491]	9	hSpCas9	negative selection	5892356
35871939	35871962	19	+	27260156	COLO741	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.5020110328113842	[430]	[403,346,413]	-8	hSpCas9	negative selection	5956638
35870948	35870971	19	-	27260156	COLO741	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.06887246915137679	[633]	[898,700,728]	-1	hSpCas9	negative selection	5956639
35870931	35870954	19	+	27260156	COLO741	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.0022288738215315296	[589]	[667,767,808]	0	hSpCas9	negative selection	5956640
35872592	35872615	19	+	27260156	CAL120	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.31683548422037777	[661]	[938,720,1397]	5	hSpCas9	negative selection	6013605
35871940	35871963	19	-	27260156	CAL120	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.4903156184235756	[559]	[967,1228,741]	7	hSpCas9	negative selection	6013606
35872501	35872524	19	-	27260156	CAL120	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.28348747193896673	[343]	[491,630,436]	4	hSpCas9	negative selection	6013607
35871939	35871962	19	+	27260156	CAL120	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	0.07935593047575597	[430]	[598,560,544]	1	hSpCas9	negative selection	6077889
35870948	35870971	19	-	27260156	CAL120	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.28013081716549754	[633]	[944,985,940]	4	hSpCas9	negative selection	6077890
35870931	35870954	19	+	27260156	CAL120	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	0.21577686718993855	[589]	[1009,705,864]	3	hSpCas9	negative selection	6077891
35872592	35872615	19	+	27260156	CADOES1	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.3570657873014701	[661]	[510,522,378,510]	-6	hSpCas9	negative selection	6134856
35871940	35871963	19	-	27260156	CADOES1	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.34972235606292035	[559]	[425,433,464,305]	-6	hSpCas9	negative selection	6134857
35872501	35872524	19	-	27260156	CADOES1	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.47238291146842265	[343]	[293,547,416,519]	7	hSpCas9	negative selection	6134858
35871939	35871962	19	+	27260156	CADOES1	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.29537428205705546	[430]	[316,477,310,195]	-5	hSpCas9	negative selection	6199140
35870948	35870971	19	-	27260156	CADOES1	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.15904229735119974	[633]	[531,697,691,713]	2	hSpCas9	negative selection	6199141
35870931	35870954	19	+	27260156	CADOES1	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.32810741195179716	[589]	[424,364,528,428]	-5	hSpCas9	negative selection	6199142
35872592	35872615	19	+	27260156	EWS502	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.10513298977224772	[661]	[663,669,589,679]	-2	hSpCas9	negative selection	6256107
35871940	35871963	19	-	27260156	EWS502	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.1252741560823078	[559]	[575,535,514,541]	-2	hSpCas9	negative selection	6256108
35872501	35872524	19	-	27260156	EWS502	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.32696735328069076	[343]	[347,509,416,569]	6	hSpCas9	negative selection	6256109
35871939	35871962	19	+	27260156	EWS502	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.5372174251003337	[430]	[315,367,269,298]	-7	hSpCas9	negative selection	6320391
35870948	35870971	19	-	27260156	EWS502	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.1736532845150346	[633]	[645,428,636,673]	-3	hSpCas9	negative selection	6320392
35870931	35870954	19	+	27260156	EWS502	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.375403879270334	[589]	[476,399,462,596]	-6	hSpCas9	negative selection	6320393
35872592	35872615	19	+	27260156	EW8	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.6631956799104833	[661]	[374,398,288,303]	-8	hSpCas9	negative selection	6377358
35871940	35871963	19	-	27260156	EW8	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.5422254085543012	[559]	[378,301,276,300]	-7	hSpCas9	negative selection	6377359
35872501	35872524	19	-	27260156	EW8	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.1682148179384999	[343]	[221,395,261,370]	3	hSpCas9	negative selection	6377360
35871939	35871962	19	+	27260156	EW8	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.7964902035562051	[430]	[276,212,143,187]	-8	hSpCas9	negative selection	6441642
35870948	35870971	19	-	27260156	EW8	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.3736203143053112	[633]	[398,394,416,370]	-6	hSpCas9	negative selection	6441643
35870931	35870954	19	+	27260156	EW8	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.8056142207115569	[589]	[314,269,285,224]	-8	hSpCas9	negative selection	6441644
35872592	35872615	19	+	27260156	CORL105	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.13591196602402106	[661]	[993,566,709,563]	-3	hSpCas9	negative selection	6498609
35871940	35871963	19	-	27260156	CORL105	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.09869678974889656	[559]	[641,727,782,664]	1	hSpCas9	negative selection	6498610
35872501	35872524	19	-	27260156	CORL105	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.6625367856627594	[343]	[589,647,683,632]	9	hSpCas9	negative selection	6498611
35871939	35871962	19	+	27260156	CORL105	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.6314625552505038	[430]	[260,386,398,263]	-8	hSpCas9	negative selection	6562893
35870948	35870971	19	-	27260156	CORL105	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.06871374982946593	[633]	[675,699,992,775]	1	hSpCas9	negative selection	6562894
35870931	35870954	19	+	27260156	CORL105	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.3447590494368732	[589]	[522,463,713,501]	-6	hSpCas9	negative selection	6562895
35872592	35872615	19	+	27260156	HS294T	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.0751782352945839	[661]	[279,194,270,345]	1	hSpCas9	negative selection	6619860
35871940	35871963	19	-	27260156	HS294T	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.045154702145073	[559]	[197,162,252,230]	0	hSpCas9	negative selection	6619861
35872501	35872524	19	-	27260156	HS294T	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.7946799810202796	[343]	[187,119,266,379]	8	hSpCas9	negative selection	6619862
35871939	35871962	19	+	27260156	HS294T	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.11633442313926982	[430]	[74,133,123,316]	-2	hSpCas9	negative selection	6684144
35870948	35870971	19	-	27260156	HS294T	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.5351023527002876	[633]	[206,289,375,604]	7	hSpCas9	negative selection	6684145
35870931	35870954	19	+	27260156	HS294T	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.05214905619008836	[589]	[196,164,318,198]	0	hSpCas9	negative selection	6684146
35872592	35872615	19	+	27260156	HCC44	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.4249250043979449	[661]	[1016,850,1108,1073]	7	hSpCas9	negative selection	6741111
35871940	35871963	19	-	27260156	HCC44	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.21428016623219986	[559]	[745,434,888,926]	3	hSpCas9	negative selection	6741112
35872501	35872524	19	-	27260156	HCC44	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.5510056695539789	[343]	[744,406,690,494]	8	hSpCas9	negative selection	6741113
35871939	35871962	19	+	27260156	HCC44	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	0.32173858314311987	[430]	[605,652,643,530]	5	hSpCas9	negative selection	6805395
35870948	35870971	19	-	27260156	HCC44	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.24498020556465966	[633]	[907,677,962,890]	4	hSpCas9	negative selection	6805396
35870931	35870954	19	+	27260156	HCC44	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.029285516907662734	[589]	[854,453,544,779]	0	hSpCas9	negative selection	6805397
35872592	35872615	19	+	27260156	G402	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.2696089183156865	[661]	[1030,647,642,418]	-3	hSpCas9	negative selection	6862362
35871940	35871963	19	-	27260156	G402	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.4036823316454534	[559]	[554,447,382,671]	-5	hSpCas9	negative selection	6862363
35872501	35872524	19	-	27260156	G402	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.09465506771247739	[343]	[738,394,395,306]	1	hSpCas9	negative selection	6862364
35871939	35871962	19	+	27260156	G402	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.8128823944932079	[430]	[374,230,249,344]	-7	hSpCas9	negative selection	6926646
35870948	35870971	19	-	27260156	G402	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.08348797210529885	[633]	[721,1083,950,533]	1	hSpCas9	negative selection	6926647
35870931	35870954	19	+	27260156	G402	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.6887242006349841	[589]	[641,342,353,466]	-7	hSpCas9	negative selection	6926648
35872592	35872615	19	+	27260156	L33	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.3103507149108343	[661]	[671,353,547,878]	6	hSpCas9	negative selection	6983613
35871940	35871963	19	-	27260156	L33	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.29796037321111535	[559]	[820,249,432,630]	6	hSpCas9	negative selection	6983614
35872501	35872524	19	-	27260156	L33	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.43237000854996394	[343]	[471,212,266,439]	8	hSpCas9	negative selection	6983615
35871939	35871962	19	+	27260156	L33	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	0.07481041557940823	[430]	[462,216,302,341]	1	hSpCas9	negative selection	7047897
35870948	35870971	19	-	27260156	L33	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.24705415201018371	[633]	[776,269,528,731]	5	hSpCas9	negative selection	7047898
35870931	35870954	19	+	27260156	L33	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	0.12360703452892718	[589]	[618,241,469,614]	2	hSpCas9	negative selection	7047899
35872592	35872615	19	+	27260156	K562	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.48729042358868574	[661]	[910,413,285,136]	-5	hSpCas9	negative selection	7104864
35871940	35871963	19	-	27260156	K562	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.12062155533669111	[559]	[398,473,637,326]	-1	hSpCas9	negative selection	7104865
35872501	35872524	19	-	27260156	K562	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.2293586548994402	[343]	[401,177,399,434]	3	hSpCas9	negative selection	7104866
35871939	35871962	19	+	27260156	K562	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.43662276637808495	[430]	[166,196,522,233]	-5	hSpCas9	negative selection	7169148
35870948	35870971	19	-	27260156	K562	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.6617497948053676	[633]	[381,337,475,239]	-7	hSpCas9	negative selection	7169149
35870931	35870954	19	+	27260156	K562	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.12029706440958077	[589]	[513,590,269,549]	-1	hSpCas9	negative selection	7169150
35872592	35872615	19	+	27260156	HT29	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.1609423102021249	[661]	[868,1025,942,777]	3	hSpCas9	negative selection	7226115
35871940	35871963	19	-	27260156	HT29	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.17482128545915288	[559]	[711,729,506,491]	-4	hSpCas9	negative selection	7226116
35872501	35872524	19	-	27260156	HT29	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.42890250269647756	[343]	[639,638,479,507]	8	hSpCas9	negative selection	7226117
35871939	35871962	19	+	27260156	HT29	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.13582894428982412	[430]	[438,656,464,368]	-3	hSpCas9	negative selection	7290399
35870948	35870971	19	-	27260156	HT29	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.012640096426157044	[633]	[722,1008,682,712]	0	hSpCas9	negative selection	7290400
35870931	35870954	19	+	27260156	HT29	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.21800986674680273	[589]	[540,628,524,745]	-4	hSpCas9	negative selection	7290401
35872592	35872615	19	+	27260156	MHHES1	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.32174533387709103	[661]	[753,935,853,1099]	6	hSpCas9	negative selection	7347366
35871940	35871963	19	-	27260156	MHHES1	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.11161203166071981	[559]	[986,731,709,391]	2	hSpCas9	negative selection	7347367
35872501	35872524	19	-	27260156	MHHES1	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.4511121296233969	[343]	[664,580,539,377]	7	hSpCas9	negative selection	7347368
35871939	35871962	19	+	27260156	MHHES1	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.24853578207333393	[430]	[455,563,377,278]	-5	hSpCas9	negative selection	7411650
35870948	35870971	19	-	27260156	MHHES1	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.07488146191732686	[633]	[922,730,711,663]	1	hSpCas9	negative selection	7411651
35870931	35870954	19	+	27260156	MHHES1	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.20706052716579101	[589]	[871,735,450,337]	-4	hSpCas9	negative selection	7411652
35872592	35872615	19	+	27260156	MEWO	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.16762968997915229	[661]	[916,630,581]	3	hSpCas9	negative selection	7468617
35871940	35871963	19	-	27260156	MEWO	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.10149078855750093	[559]	[776,521,428]	2	hSpCas9	negative selection	7468618
35872501	35872524	19	-	27260156	MEWO	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.29544648680277075	[343]	[582,243,394]	6	hSpCas9	negative selection	7468619
35871939	35871962	19	+	27260156	MEWO	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.021383375002618013	[430]	[490,386,331]	0	hSpCas9	negative selection	7532901
35870948	35870971	19	-	27260156	MEWO	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.2135577336748331	[633]	[617,329,607]	-5	hSpCas9	negative selection	7532902
35870931	35870954	19	+	27260156	MEWO	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.2360290212828376	[589]	[531,507,377]	-5	hSpCas9	negative selection	7532903
35872592	35872615	19	+	27260156	LNCAPCLONEFGC	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.1936354469403283	[661]	[732,702,754,559]	3	hSpCas9	negative selection	7589868
35871940	35871963	19	-	27260156	LNCAPCLONEFGC	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.3395484396297148	[559]	[311,348,518,445]	-5	hSpCas9	negative selection	7589869
35872501	35872524	19	-	27260156	LNCAPCLONEFGC	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.3547463846583283	[343]	[267,300,683,391]	5	hSpCas9	negative selection	7589870
35871939	35871962	19	+	27260156	LNCAPCLONEFGC	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.04254799431956137	[430]	[345,273,522,401]	0	hSpCas9	negative selection	7654152
35870948	35870971	19	-	27260156	LNCAPCLONEFGC	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.13907077444324983	[633]	[486,629,825,617]	2	hSpCas9	negative selection	7654153
35870931	35870954	19	+	27260156	LNCAPCLONEFGC	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.4248009156720559	[589]	[330,353,387,521]	-6	hSpCas9	negative selection	7654154
35872592	35872615	19	+	27260156	PANC0327	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.03427897163260257	[661]	[547,335,893,547]	0	hSpCas9	negative selection	7711119
35871940	35871963	19	-	27260156	PANC0327	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.06236037544942741	[559]	[422,460,484,707]	0	hSpCas9	negative selection	7711120
35872501	35872524	19	-	27260156	PANC0327	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.28126469153363043	[343]	[506,345,466,179]	4	hSpCas9	negative selection	7711121
35871939	35871962	19	+	27260156	PANC0327	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.025176043310586274	[430]	[354,269,495,395]	0	hSpCas9	negative selection	7775403
35870948	35870971	19	-	27260156	PANC0327	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.08747625942273957	[633]	[597,407,686,724]	1	hSpCas9	negative selection	7775404
35870931	35870954	19	+	27260156	PANC0327	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.5232763127230238	[589]	[264,283,504,406]	-6	hSpCas9	negative selection	7775405
35872592	35872615	19	+	27260156	NCIH2009	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.002970551966285151	[661]	[1258,971,601]	0	hSpCas9	negative selection	7832370
35871940	35871963	19	-	27260156	NCIH2009	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.024416062153014506	[559]	[760,597,948]	0	hSpCas9	negative selection	7832371
35872501	35872524	19	-	27260156	NCIH2009	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.40560035892495155	[343]	[661,519,733]	5	hSpCas9	negative selection	7832372
35871939	35871962	19	+	27260156	NCIH2009	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.4133594043352117	[430]	[512,326,529]	-5	hSpCas9	negative selection	7896654
35870948	35870971	19	-	27260156	NCIH2009	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.6733569058084594	[633]	[1287,1352,1570]	8	hSpCas9	negative selection	7896655
35870931	35870954	19	+	27260156	NCIH2009	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.7203254081377408	[589]	[482,594,416]	-7	hSpCas9	negative selection	7896656
35872592	35872615	19	+	27260156	NCIH1373	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.08482405601238213	[661]	[797,899,602,124]	-1	hSpCas9	negative selection	7953621
35871940	35871963	19	-	27260156	NCIH1373	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.294608567064697	[559]	[489,585,482,123]	-3	hSpCas9	negative selection	7953622
35872501	35872524	19	-	27260156	NCIH1373	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	1.135428063881579	[343]	[1444,766,720,140]	9	hSpCas9	negative selection	7953623
35871939	35871962	19	+	27260156	NCIH1373	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.3606216454096374	[430]	[313,282,256,175]	-4	hSpCas9	negative selection	8017905
35870948	35870971	19	-	27260156	NCIH1373	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.44934431281587545	[633]	[1442,851,611,280]	4	hSpCas9	negative selection	8017906
35870931	35870954	19	+	27260156	NCIH1373	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-1.5310026643875907	[589]	[241,269,217,46]	-9	hSpCas9	negative selection	8017907
35872592	35872615	19	+	27260156	PATU8902	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.08455802578770177	[661]	[1181,1017,713,1064]	0	hSpCas9	negative selection	8074872
35871940	35871963	19	-	27260156	PATU8902	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.2830321873852104	[559]	[534,461,644,953]	-3	hSpCas9	negative selection	8074873
35872501	35872524	19	-	27260156	PATU8902	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.3111550196988869	[343]	[552,1076,168,698]	3	hSpCas9	negative selection	8074874
35871939	35871962	19	+	27260156	PATU8902	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.5350964262926201	[430]	[429,356,377,508]	-5	hSpCas9	negative selection	8139156
35870948	35870971	19	-	27260156	PATU8902	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.17576315510080648	[633]	[893,999,481,826]	-2	hSpCas9	negative selection	8139157
35870931	35870954	19	+	27260156	PATU8902	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.8840010671191663	[589]	[294,418,558,480]	-7	hSpCas9	negative selection	8139158
35872592	35872615	19	+	27260156	PANC1	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.20738776536796222	[661]	[666,865,511,617]	3	hSpCas9	negative selection	8196123
35871940	35871963	19	-	27260156	PANC1	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.12619200376013395	[559]	[562,336,459,666]	2	hSpCas9	negative selection	8196124
35872501	35872524	19	-	27260156	PANC1	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.3264126800395656	[343]	[396,482,423,219]	5	hSpCas9	negative selection	8196125
35871939	35871962	19	+	27260156	PANC1	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.4055523078812713	[430]	[235,393,397,134]	-6	hSpCas9	negative selection	8260407
35870948	35870971	19	-	27260156	PANC1	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.12855480293396399	[633]	[553,753,626,487]	2	hSpCas9	negative selection	8260408
35870931	35870954	19	+	27260156	PANC1	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.25278721539764587	[589]	[451,422,400,417]	-4	hSpCas9	negative selection	8260409
35872592	35872615	19	+	27260156	PANC0813	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.08986128732769583	[661]	[885,825,823,780]	1	hSpCas9	negative selection	8317374
35871940	35871963	19	-	27260156	PANC0813	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.09212273520744077	[559]	[517,644,617,673]	-1	hSpCas9	negative selection	8317375
35872501	35872524	19	-	27260156	PANC0813	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.7541122730072658	[343]	[705,713,592,711]	9	hSpCas9	negative selection	8317376
35871939	35871962	19	+	27260156	PANC0813	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.5649016537438563	[430]	[412,291,380,291]	-7	hSpCas9	negative selection	8381658
35870948	35870971	19	-	27260156	PANC0813	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.05134750261641269	[633]	[821,730,830,709]	0	hSpCas9	negative selection	8381659
35870931	35870954	19	+	27260156	PANC0813	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.44112552617465717	[589]	[556,453,413,613]	-6	hSpCas9	negative selection	8381660
35872592	35872615	19	+	27260156	RDES	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.26407919595181606	[661]	[483,569,783,739]	-4	hSpCas9	negative selection	8438625
35871940	35871963	19	-	27260156	RDES	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.1327649483537796	[559]	[532,549,636,634]	-2	hSpCas9	negative selection	8438626
35872501	35872524	19	-	27260156	RDES	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.6292797695284033	[343]	[364,649,678,821]	8	hSpCas9	negative selection	8438627
35871939	35871962	19	+	27260156	RDES	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.36186484499569493	[430]	[249,303,520,520]	-6	hSpCas9	negative selection	8502909
35870948	35870971	19	-	27260156	RDES	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.11805415457318708	[633]	[585,589,970,1116]	2	hSpCas9	negative selection	8502910
35870931	35870954	19	+	27260156	RDES	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	0.0015016899300822617	[589]	[699,520,650,858]	0	hSpCas9	negative selection	8502911
35872592	35872615	19	+	27260156	PC3	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.11395853706416004	[661]	[566,595,1003,790]	2	hSpCas9	negative selection	8559876
35871940	35871963	19	-	27260156	PC3	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.07358634218938728	[559]	[368,541,737,567]	-2	hSpCas9	negative selection	8559877
35872501	35872524	19	-	27260156	PC3	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.021453883444097877	[343]	[245,287,569,386]	0	hSpCas9	negative selection	8559878
35871939	35871962	19	+	27260156	PC3	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.016852758945193794	[430]	[247,306,551,698]	0	hSpCas9	negative selection	8624160
35870948	35870971	19	-	27260156	PC3	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.07557836577596821	[633]	[385,686,981,516]	-2	hSpCas9	negative selection	8624161
35870931	35870954	19	+	27260156	PC3	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	0.12511362448305718	[589]	[340,537,997,923]	3	hSpCas9	negative selection	8624162
35872592	35872615	19	+	27260156	PATU8988T	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.1682478125376089	[661]	[758,478,511,514]	-3	hSpCas9	negative selection	8681127
35871940	35871963	19	-	27260156	PATU8988T	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.2551015714573052	[559]	[353,432,335,710]	-4	hSpCas9	negative selection	8681128
35872501	35872524	19	-	27260156	PATU8988T	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.02773850992314636	[343]	[214,418,390,336]	0	hSpCas9	negative selection	8681129
35871939	35871962	19	+	27260156	PATU8988T	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.7452815916318495	[430]	[184,294,247,271]	-8	hSpCas9	negative selection	8745411
35870948	35870971	19	-	27260156	PATU8988T	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.4731661012403387	[633]	[457,483,542,268]	-6	hSpCas9	negative selection	8745412
35870931	35870954	19	+	27260156	PATU8988T	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.7928665228969605	[589]	[305,334,292,387]	-8	hSpCas9	negative selection	8745413
35872592	35872615	19	+	27260156	T47D	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.12371742584580214	[661]	[660,693,710,767]	-3	hSpCas9	negative selection	8802378
35871940	35871963	19	-	27260156	T47D	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.2888499362863517	[559]	[528,488,443,683]	-6	hSpCas9	negative selection	8802379
35872501	35872524	19	-	27260156	T47D	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.3702535272740654	[343]	[569,431,597,476]	7	hSpCas9	negative selection	8802380
35871939	35871962	19	+	27260156	T47D	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.2672557720800706	[430]	[430,361,397,484]	-5	hSpCas9	negative selection	8866662
35870948	35870971	19	-	27260156	T47D	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.09398545569344413	[633]	[817,790,743,800]	2	hSpCas9	negative selection	8866663
35870931	35870954	19	+	27260156	T47D	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.1383372439838924	[589]	[607,597,674,617]	-3	hSpCas9	negative selection	8866664
35872592	35872615	19	+	27260156	SU8686	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-1.0870963783845955	[661]	[276,273,263,447]	-8	hSpCas9	negative selection	8923629
35871940	35871963	19	-	27260156	SU8686	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.6564702428471136	[559]	[281,313,447,382]	-7	hSpCas9	negative selection	8923630
35872501	35872524	19	-	27260156	SU8686	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.482032844252217	[343]	[466,420,479,554]	7	hSpCas9	negative selection	8923631
35871939	35871962	19	+	27260156	SU8686	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-1.0793735732853391	[430]	[245,180,170,206]	-8	hSpCas9	negative selection	8987913
35870948	35870971	19	-	27260156	SU8686	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.5649573085997206	[633]	[456,392,376,476]	-7	hSpCas9	negative selection	8987914
35870931	35870954	19	+	27260156	SU8686	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-1.1812164183605218	[589]	[265,260,218,285]	-9	hSpCas9	negative selection	8987915
35872592	35872615	19	+	27260156	SKES1	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.07299803524317838	[661]	[736,759,612,677]	1	hSpCas9	negative selection	9044880
35871940	35871963	19	-	27260156	SKES1	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.3279522591658228	[559]	[575,399,459,361]	-6	hSpCas9	negative selection	9044881
35872501	35872524	19	-	27260156	SKES1	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.5521710412560475	[343]	[658,470,408,488]	9	hSpCas9	negative selection	9044882
35871939	35871962	19	+	27260156	SKES1	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.25142977159210045	[430]	[356,398,366,325]	-5	hSpCas9	negative selection	9109164
35870948	35870971	19	-	27260156	SKES1	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.09824655786812048	[633]	[759,790,620,567]	2	hSpCas9	negative selection	9109165
35870931	35870954	19	+	27260156	SKES1	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.10632578353574373	[589]	[591,622,591,405]	-2	hSpCas9	negative selection	9109166
35872592	35872615	19	+	27260156	TOV112D	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	-0.052252479848008515	[661]	[779,858,431,553]	-1	hSpCas9	negative selection	9166131
35871940	35871963	19	-	27260156	TOV112D	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	0.12664605681716673	[559]	[459,953,617,490]	2	hSpCas9	negative selection	9166132
35872501	35872524	19	-	27260156	TOV112D	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.597988763912326	[343]	[573,471,642,391]	9	hSpCas9	negative selection	9166133
35871939	35871962	19	+	27260156	TOV112D	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.32180358633267	[430]	[368,441,298,297]	-6	hSpCas9	negative selection	9230415
35870948	35870971	19	-	27260156	TOV112D	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.23231041531282687	[633]	[593,871,654,875]	4	hSpCas9	negative selection	9230416
35870931	35870954	19	+	27260156	TOV112D	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.46077354984217767	[589]	[481,427,351,457]	-7	hSpCas9	negative selection	9230417
35872592	35872615	19	+	27260156	TC71	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.05647708037401633	[661]	[617,854,725,756]	1	hSpCas9	negative selection	9287382
35871940	35871963	19	-	27260156	TC71	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.19253217005178855	[559]	[489,436,515,667]	-5	hSpCas9	negative selection	9287383
35872501	35872524	19	-	27260156	TC71	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.301068002364314	[343]	[378,470,452,519]	7	hSpCas9	negative selection	9287384
35871939	35871962	19	+	27260156	TC71	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.20415068805431952	[430]	[360,339,447,457]	-5	hSpCas9	negative selection	9351666
35870948	35870971	19	-	27260156	TC71	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	-0.008359982309672942	[633]	[680,592,651,783]	0	hSpCas9	negative selection	9351667
35870931	35870954	19	+	27260156	TC71	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.06801726313441264	[589]	[523,716,581,591]	-2	hSpCas9	negative selection	9351668
35872592	35872615	19	+	27260156	TC32	viability	TAGGATGCGCCAGATTAATGAGG	APLP1	ENSG00000105290	0.0020967416190995625	[661]	[631,473,722,701]	0	hSpCas9	negative selection	9408633
35871940	35871963	19	-	27260156	TC32	viability	TCCACGAAGTAATCATCTACTGG	APLP1	ENSG00000105290	-0.1987225615645598	[559]	[426,257,658,586]	-4	hSpCas9	negative selection	9408634
35872501	35872524	19	-	27260156	TC32	viability	GTAAATATCCACACCGTCTGTGG	APLP1	ENSG00000105290	0.49868988794208646	[343]	[487,342,620,411]	8	hSpCas9	negative selection	9408635
35871939	35871962	19	+	27260156	TC32	viability	GCCAGTAGATGATTACTTCGTGG	APLP1	ENSG00000105290	-0.49438956397627853	[430]	[229,126,559,336]	-7	hSpCas9	negative selection	9472917
35870948	35870971	19	-	27260156	TC32	viability	ACCCCCGCACCAGCGCTCCATGG	APLP1	ENSG00000105290	0.015793945679868693	[633]	[598,459,780,618]	0	hSpCas9	negative selection	9472918
35870931	35870954	19	+	27260156	TC32	viability	GGCTACGCAGGCCATCCCCATGG	APLP1	ENSG00000105290	-0.23238483283152878	[589]	[372,406,498,630]	-4	hSpCas9	negative selection	9472919
35868651	35868674	19	-	27869803	HPAFII	viability after 27 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-1.1030078654577193	[77]	[29,9,NaN]	-6	hSpCas9	negative selection	9567319
35869681	35869704	19	-	27869803	HPAFII	viability after 27 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.9872234008031053	[195]	[521,313,NaN]	9	hSpCas9	negative selection	9567320
35871014	35871037	19	-	27869803	HPAFII	viability after 27 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-0.4734344780362718	[120]	[17,68,NaN]	-4	hSpCas9	negative selection	9567321
35871319	35871342	19	+	27869803	HPAFII	viability after 27 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.6505570612773293	[178]	[114,174,NaN]	5	hSpCas9	negative selection	9567322
35871661	35871684	19	-	27869803	HPAFII	viability after 27 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-0.8370653855876862	[176]	[20,77,NaN]	-5	hSpCas9	negative selection	9567323
35871951	35871974	19	+	27869803	HPAFII	viability after 27 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-1.0541496302005793	[106]	[1,47,NaN]	-6	hSpCas9	negative selection	9567324
35868651	35868674	19	-	27869803	HPAFII	viability after 15 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-1.4366609764580767	[77]	[46,20,NaN]	-8	hSpCas9	negative selection	9649768
35869681	35869704	19	-	27869803	HPAFII	viability after 15 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.5081365169305758	[195]	[978,362,NaN]	9	hSpCas9	negative selection	9649769
35871014	35871037	19	-	27869803	HPAFII	viability after 15 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-0.21746393220375504	[120]	[72,135,NaN]	-3	hSpCas9	negative selection	9649770
35871319	35871342	19	+	27869803	HPAFII	viability after 15 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.10226962654263028	[178]	[298,148,NaN]	1	hSpCas9	negative selection	9649771
35871661	35871684	19	-	27869803	HPAFII	viability after 15 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	0.060451969483255374	[176]	[206,192,NaN]	0	hSpCas9	negative selection	9649772
35871951	35871974	19	+	27869803	HPAFII	viability after 15 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-0.7362520279997944	[106]	[52,78,NaN]	-7	hSpCas9	negative selection	9649773
35868651	35868674	19	-	27869803	ASPC1	viability after 36 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	0.7099108451013851	[106]	[155,36,12]	7	hSpCas9	negative selection	9732217
35869681	35869704	19	-	27869803	ASPC1	viability after 36 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.0004531278845006	[756]	[584,672,368]	8	hSpCas9	negative selection	9732218
35871014	35871037	19	-	27869803	ASPC1	viability after 36 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	1.3978285239302515	[158]	[17,0,349]	9	hSpCas9	negative selection	9732219
35871319	35871342	19	+	27869803	ASPC1	viability after 36 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	-0.19022958838958215	[366]	[100,71,150]	-2	hSpCas9	negative selection	9732220
35871661	35871684	19	-	27869803	ASPC1	viability after 36 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	0.1788868786406851	[311]	[261,137,12]	1	hSpCas9	negative selection	9732221
35871951	35871974	19	+	27869803	ASPC1	viability after 36 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-0.05546794957551482	[288]	[26,148,103]	0	hSpCas9	negative selection	9732222
35868651	35868674	19	-	27869803	PATU8988S	viability after 35 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-0.1011436211002188	[164]	[41,81,NaN]	-1	hSpCas9	negative selection	9814666
35869681	35869704	19	-	27869803	PATU8988S	viability after 35 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	-0.29411019553973333	[625]	[259,150,NaN]	-3	hSpCas9	negative selection	9814667
35871014	35871037	19	-	27869803	PATU8988S	viability after 35 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-1.065075876223806	[215]	[75,6,NaN]	-7	hSpCas9	negative selection	9814668
35871319	35871342	19	+	27869803	PATU8988S	viability after 35 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	-1.0571979145155121	[397]	[90,62,NaN]	-7	hSpCas9	negative selection	9814669
35871661	35871684	19	-	27869803	PATU8988S	viability after 35 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-0.3436943039251761	[426]	[143,126,NaN]	-4	hSpCas9	negative selection	9814670
35871951	35871974	19	+	27869803	PATU8988S	viability after 35 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	0.8002417697361209	[256]	[287,71,NaN]	8	hSpCas9	negative selection	9814671
35868651	35868674	19	-	27869803	PATU8988S	viability after 31 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-0.1523960660916468	[164]	[45,75,NaN]	-2	hSpCas9	negative selection	9897115
35869681	35869704	19	-	27869803	PATU8988S	viability after 31 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	0.03483729461140017	[625]	[227,290,NaN]	0	hSpCas9	negative selection	9897116
35871014	35871037	19	-	27869803	PATU8988S	viability after 31 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-0.34679044374251133	[215]	[94,32,NaN]	-4	hSpCas9	negative selection	9897117
35871319	35871342	19	+	27869803	PATU8988S	viability after 31 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	-1.0775488767158483	[397]	[61,91,NaN]	-8	hSpCas9	negative selection	9897118
35871661	35871684	19	-	27869803	PATU8988S	viability after 31 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-0.5418196736336867	[426]	[90,149,NaN]	-5	hSpCas9	negative selection	9897119
35871951	35871974	19	+	27869803	PATU8988S	viability after 31 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	0.7112504750262547	[256]	[253,57,NaN]	8	hSpCas9	negative selection	9897120
35868651	35868674	19	-	27869803	HPAFII	viability after 35 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-1.2011667788581206	[77]	[11,22,NaN]	-6	hSpCas9	negative selection	9979564
35869681	35869704	19	-	27869803	HPAFII	viability after 35 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.7413012837092958	[195]	[287,380,NaN]	9	hSpCas9	negative selection	9979565
35871014	35871037	19	-	27869803	HPAFII	viability after 35 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-0.4076450975520267	[120]	[48,42,NaN]	-3	hSpCas9	negative selection	9979566
35871319	35871342	19	+	27869803	HPAFII	viability after 35 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.8142725166880482	[178]	[140,179,NaN]	5	hSpCas9	negative selection	9979567
35871661	35871684	19	-	27869803	HPAFII	viability after 35 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-1.4620091642111988	[176]	[24,40,NaN]	-7	hSpCas9	negative selection	9979568
35871951	35871974	19	+	27869803	HPAFII	viability after 35 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-0.8223914130498196	[106]	[0,63,NaN]	-5	hSpCas9	negative selection	9979569
35868651	35868674	19	-	27869803	HPAFII	viability after 31 days	GACTTAGACCGCGAGCAGCGGGG	APLP1	ENSG00000105290	-0.3104347408031727	[77]	[41,27,NaN]	-2	hSpCas9	negative selection	10062013
35869681	35869704	19	-	27869803	HPAFII	viability after 31 days	GCCCGCATAGTCCAGCCACCTGG	APLP1	ENSG00000105290	1.7094549415751834	[195]	[431,280,NaN]	9	hSpCas9	negative selection	10062014
35871014	35871037	19	-	27869803	HPAFII	viability after 31 days	GGACTCACGCAGGCAGCGGAAGG	APLP1	ENSG00000105290	-1.0964828215173132	[120]	[3,61,NaN]	-6	hSpCas9	negative selection	10062015
35871319	35871342	19	+	27869803	HPAFII	viability after 31 days	TTCAACCCGGAGGCATCAGGAGG	APLP1	ENSG00000105290	0.29416291381425097	[178]	[115,130,NaN]	2	hSpCas9	negative selection	10062016
35871661	35871684	19	-	27869803	HPAFII	viability after 31 days	ACGGAACCGATCCGAGCCACAGG	APLP1	ENSG00000105290	-1.301015094755442	[176]	[24,56,NaN]	-7	hSpCas9	negative selection	10062017
35871951	35871974	19	+	27869803	HPAFII	viability after 31 days	TTACTTCGTGGAGCCTCCGCAGG	APLP1	ENSG00000105290	-1.3248518032310324	[106]	[0,48,NaN]	-7	hSpCas9	negative selection	10062018
35874778	35874801	19	+	28162770	P31FUJ	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.3800281575975566	[267]	[241]	-3	hSpCas9	negative selection	10112031
35874577	35874600	19	-	28162770	P31FUJ	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-0.2328022044143787	[70]	[70]	-2	hSpCas9	negative selection	10112032
35868653	35868676	19	-	28162770	P31FUJ	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-0.09764262113274269	[111]	[122]	-1	hSpCas9	negative selection	10112033
35869735	35869758	19	-	28162770	P31FUJ	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-0.40693945714360547	[342]	[303]	-4	hSpCas9	negative selection	10112034
35870942	35870965	19	-	28162770	P31FUJ	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	-0.4571195026753184	[124]	[106]	-4	hSpCas9	negative selection	10112035
35870997	35871020	19	-	28162770	P31FUJ	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	0.43962313755711735	[31]	[50]	5	hSpCas9	negative selection	10112036
35871309	35871332	19	+	28162770	P31FUJ	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.20426160119446402	[584]	[791]	2	hSpCas9	negative selection	10112037
35871328	35871351	19	+	28162770	P31FUJ	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-1.111495908192245	[170]	[92]	-7	hSpCas9	negative selection	10112038
35872536	35872559	19	+	28162770	P31FUJ	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	0.4214229587438913	[121]	[191]	5	hSpCas9	negative selection	10112039
35872565	35872588	19	+	28162770	P31FUJ	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-1.2328022044143787	[33]	[16]	-7	hSpCas9	negative selection	10112040
35874778	35874801	19	+	28162770	TF1	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	NaN	[NaN]	[40]	1	hSpCas9	negative selection	10281397
35874577	35874600	19	-	28162770	TF1	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10281398
35868653	35868676	19	-	28162770	TF1	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10281399
35869735	35869758	19	-	28162770	TF1	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10281400
35870942	35870965	19	-	28162770	TF1	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10281401
35870997	35871020	19	-	28162770	TF1	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10281402
35871309	35871332	19	+	28162770	TF1	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	NaN	[NaN]	[289]	1	hSpCas9	negative selection	10281403
35871328	35871351	19	+	28162770	TF1	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10281404
35872536	35872559	19	+	28162770	TF1	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10281405
35872565	35872588	19	+	28162770	TF1	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10281406
35874778	35874801	19	+	28162770	SKM1	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.6367868255550981	[72]	[82]	-5	hSpCas9	negative selection	10450763
35874577	35874600	19	-	28162770	SKM1	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-1.7480011165782288	[18]	[9]	-8	hSpCas9	negative selection	10450764
35868653	35868676	19	-	28162770	SKM1	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-0.23703919730084932	[41]	[62]	-2	hSpCas9	negative selection	10450765
35869735	35869758	19	-	28162770	SKM1	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	1.398727674091798	[61]	[288]	9	hSpCas9	negative selection	10450766
35870942	35870965	19	-	28162770	SKM1	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	0.281091794942098	[26]	[57]	2	hSpCas9	negative selection	10450767
35870997	35871020	19	-	28162770	SKM1	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	1.690448302914783	[16]	[96]	9	hSpCas9	negative selection	10450768
35871309	35871332	19	+	28162770	SKM1	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.41804938981094897	[115]	[273]	4	hSpCas9	negative selection	10450769
35871328	35871351	19	+	28162770	SKM1	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-0.030588319833422917	[25]	[44]	0	hSpCas9	negative selection	10450770
35872536	35872559	19	+	28162770	SKM1	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	0.5860830406150715	[25]	[68]	5	hSpCas9	negative selection	10450771
35872565	35872588	19	+	28162770	SKM1	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-2.0443941193584534	[6]	[2]	-8	hSpCas9	negative selection	10450772
35874778	35874801	19	+	28162770	SKM1	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.6367868255550981	[72]	[82]	-5	hSpCas9	negative selection	10620129
35874577	35874600	19	-	28162770	SKM1	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-1.7480011165782288	[18]	[9]	-8	hSpCas9	negative selection	10620130
35868653	35868676	19	-	28162770	SKM1	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-0.23703919730084932	[41]	[62]	-2	hSpCas9	negative selection	10620131
35869735	35869758	19	-	28162770	SKM1	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	1.398727674091798	[61]	[288]	9	hSpCas9	negative selection	10620132
35870942	35870965	19	-	28162770	SKM1	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	0.281091794942098	[26]	[57]	2	hSpCas9	negative selection	10620133
35870997	35871020	19	-	28162770	SKM1	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	1.690448302914783	[16]	[96]	9	hSpCas9	negative selection	10620134
35871309	35871332	19	+	28162770	SKM1	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.41804938981094897	[115]	[273]	4	hSpCas9	negative selection	10620135
35871328	35871351	19	+	28162770	SKM1	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-0.030588319833422917	[25]	[44]	0	hSpCas9	negative selection	10620136
35872536	35872559	19	+	28162770	SKM1	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	0.5860830406150715	[25]	[68]	5	hSpCas9	negative selection	10620137
35872565	35872588	19	+	28162770	SKM1	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-2.0443941193584534	[6]	[2]	-8	hSpCas9	negative selection	10620138
35874778	35874801	19	+	28162770	PL21	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	0.1895703727791329	[273]	[135]	1	hSpCas9	negative selection	10789495
35874577	35874600	19	-	28162770	PL21	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	1.086482832693753	[65]	[60]	8	hSpCas9	negative selection	10789496
35868653	35868676	19	-	28162770	PL21	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-0.1941393246227261	[91]	[34]	-1	hSpCas9	negative selection	10789497
35869735	35869758	19	-	28162770	PL21	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	0.6278213230203868	[283]	[190]	5	hSpCas9	negative selection	10789498
35870942	35870965	19	-	28162770	PL21	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	-0.37101708670680544	[103]	[34]	-3	hSpCas9	negative selection	10789499
35870997	35871020	19	-	28162770	PL21	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	1.344529523824495	[37]	[41]	9	hSpCas9	negative selection	10789500
35871309	35871332	19	+	28162770	PL21	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.5845454951145008	[356]	[232]	5	hSpCas9	negative selection	10789501
35871328	35871351	19	+	28162770	PL21	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	0.12213710248804688	[75]	[35]	1	hSpCas9	negative selection	10789502
35872536	35872559	19	+	28162770	PL21	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	-0.7825823940788443	[82]	[20]	-5	hSpCas9	negative selection	10789503
35872565	35872588	19	+	28162770	PL21	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-2.929143402455647	[34]	[1]	-9	hSpCas9	negative selection	10789504
35874778	35874801	19	+	28162770	P31FUJ	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.3800281575975566	[267]	[241]	-3	hSpCas9	negative selection	10958861
35874577	35874600	19	-	28162770	P31FUJ	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-0.2328022044143787	[70]	[70]	-2	hSpCas9	negative selection	10958862
35868653	35868676	19	-	28162770	P31FUJ	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-0.09764262113274269	[111]	[122]	-1	hSpCas9	negative selection	10958863
35869735	35869758	19	-	28162770	P31FUJ	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-0.40693945714360547	[342]	[303]	-4	hSpCas9	negative selection	10958864
35870942	35870965	19	-	28162770	P31FUJ	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	-0.4571195026753184	[124]	[106]	-4	hSpCas9	negative selection	10958865
35870997	35871020	19	-	28162770	P31FUJ	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	0.43962313755711735	[31]	[50]	5	hSpCas9	negative selection	10958866
35871309	35871332	19	+	28162770	P31FUJ	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.20426160119446402	[584]	[791]	2	hSpCas9	negative selection	10958867
35871328	35871351	19	+	28162770	P31FUJ	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-1.111495908192245	[170]	[92]	-7	hSpCas9	negative selection	10958868
35872536	35872559	19	+	28162770	P31FUJ	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	0.4214229587438913	[121]	[191]	5	hSpCas9	negative selection	10958869
35872565	35872588	19	+	28162770	P31FUJ	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-1.2328022044143787	[33]	[16]	-7	hSpCas9	negative selection	10958870
35874778	35874801	19	+	28162770	OCIAML5	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	0.2013726880974634	[105]	[219]	1	hSpCas9	negative selection	11128227
35874577	35874600	19	-	28162770	OCIAML5	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-0.2443839936427572	[41]	[63]	-2	hSpCas9	negative selection	11128228
35868653	35868676	19	-	28162770	OCIAML5	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	0.14793342913600327	[22]	[45]	1	hSpCas9	negative selection	11128229
35869735	35869758	19	-	28162770	OCIAML5	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	0.23008247048987449	[127]	[270]	2	hSpCas9	negative selection	11128230
35870942	35870965	19	-	28162770	OCIAML5	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	-0.21346610654076764	[87]	[136]	-1	hSpCas9	negative selection	11128231
35870997	35871020	19	-	28162770	OCIAML5	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	-0.20436831479487827	[29]	[46]	-1	hSpCas9	negative selection	11128232
35871309	35871332	19	+	28162770	OCIAML5	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.24780535604839482	[285]	[612]	2	hSpCas9	negative selection	11128233
35871328	35871351	19	+	28162770	OCIAML5	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-0.9322369195479803	[73]	[69]	-5	hSpCas9	negative selection	11128234
35872536	35872559	19	+	28162770	OCIAML5	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	-0.2671040701428409	[67]	[101]	-2	hSpCas9	negative selection	11128235
35872565	35872588	19	+	28162770	OCIAML5	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-4.437029071585153	[11]	[0]	-9	hSpCas9	negative selection	11128236
35874778	35874801	19	+	28162770	EOL1	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.7330600309823875	[447]	[141]	-5	hSpCas9	negative selection	11297593
35874577	35874600	19	-	28162770	EOL1	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-1.018868700063098	[99]	[25]	-6	hSpCas9	negative selection	11297594
35868653	35868676	19	-	28162770	EOL1	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	0.2734960803916061	[200]	[127]	2	hSpCas9	negative selection	11297595
35869735	35869758	19	-	28162770	EOL1	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	0.5877435601138012	[657]	[520]	5	hSpCas9	negative selection	11297596
35870942	35870965	19	-	28162770	EOL1	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	-0.3081129852197402	[140]	[59]	-2	hSpCas9	negative selection	11297597
35870997	35871020	19	-	28162770	EOL1	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	-1.1839766852076345	[68]	[15]	-7	hSpCas9	negative selection	11297598
35871309	35871332	19	+	28162770	EOL1	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	-0.30940940139883577	[500]	[212]	-2	hSpCas9	negative selection	11297599
35871328	35871351	19	+	28162770	EOL1	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	0.0931473755462795	[120]	[67]	0	hSpCas9	negative selection	11297600
35872536	35872559	19	+	28162770	EOL1	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	-0.7635082221147251	[144]	[44]	-5	hSpCas9	negative selection	11297601
35872565	35872588	19	+	28162770	EOL1	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-1.6300410801071026	[46]	[7]	-7	hSpCas9	negative selection	11297602
35874778	35874801	19	+	28162770	MOLM13	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.09173027106211412	[394]	[267]	0	hSpCas9	negative selection	11466959
35874577	35874600	19	-	28162770	MOLM13	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	0.4404086451224717	[105]	[103]	3	hSpCas9	negative selection	11466960
35868653	35868676	19	-	28162770	MOLM13	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	0.3860123744901711	[144]	[136]	3	hSpCas9	negative selection	11466961
35869735	35869758	19	-	28162770	MOLM13	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-0.460099373540033	[507]	[266]	-3	hSpCas9	negative selection	11466962
35870942	35870965	19	-	28162770	MOLM13	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	1.3361837023327567	[148]	[271]	8	hSpCas9	negative selection	11466963
35870997	35871020	19	-	28162770	MOLM13	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	-0.39193296040716064	[48]	[26]	-2	hSpCas9	negative selection	11466964
35871309	35871332	19	+	28162770	MOLM13	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	-0.49363647064078564	[591]	[303]	-3	hSpCas9	negative selection	11466965
35871328	35871351	19	+	28162770	MOLM13	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-3.798897159150323	[153]	[7]	-9	hSpCas9	negative selection	11466966
35872536	35872559	19	+	28162770	MOLM13	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	0.7479973007373142	[139]	[169]	5	hSpCas9	negative selection	11466967
35872565	35872588	19	+	28162770	MOLM13	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	1.3284863248791623	[37]	[68]	8	hSpCas9	negative selection	11466968
35874778	35874801	19	+	28162770	HEL	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.77639142191237	[352]	[131]	-5	hSpCas9	negative selection	11636325
35874577	35874600	19	-	28162770	HEL	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-0.543674292230524	[65]	[28]	-4	hSpCas9	negative selection	11636326
35868653	35868676	19	-	28162770	HEL	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-0.6388315252708644	[140]	[57]	-4	hSpCas9	negative selection	11636327
35869735	35869758	19	-	28162770	HEL	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-0.23018647085044686	[466]	[254]	-2	hSpCas9	negative selection	11636328
35870942	35870965	19	-	28162770	HEL	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	0.5416527068860427	[132]	[123]	4	hSpCas9	negative selection	11636329
35870997	35871020	19	-	28162770	HEL	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	0.5872437194086535	[52]	[50]	5	hSpCas9	negative selection	11636330
35871309	35871332	19	+	28162770	HEL	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	-0.36603137762737514	[494]	[245]	-3	hSpCas9	negative selection	11636331
35871328	35871351	19	+	28162770	HEL	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-0.4290518510676533	[102]	[48]	-3	hSpCas9	negative selection	11636332
35872536	35872559	19	+	28162770	HEL	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	-1.8311923563320553	[149]	[26]	-7	hSpCas9	negative selection	11636333
35872565	35872588	19	+	28162770	HEL	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-0.514802444986123	[28]	[12]	-3	hSpCas9	negative selection	11636334
35874778	35874801	19	+	28162770	MV411	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.9209599809129433	[235]	[104]	-6	hSpCas9	negative selection	11805691
35874577	35874600	19	-	28162770	MV411	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-1.096516850434586	[65]	[25]	-6	hSpCas9	negative selection	11805692
35868653	35868676	19	-	28162770	MV411	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-0.10363688976410368	[124]	[97]	-1	hSpCas9	negative selection	11805693
35869735	35869758	19	-	28162770	MV411	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-0.6052663584497024	[306]	[169]	-4	hSpCas9	negative selection	11805694
35870942	35870965	19	-	28162770	MV411	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	-0.5902910203183476	[83]	[46]	-4	hSpCas9	negative selection	11805695
35870997	35871020	19	-	28162770	MV411	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	-0.7525624492172245	[27]	[13]	-5	hSpCas9	negative selection	11805696
35871309	35871332	19	+	28162770	MV411	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.0151191651622965	[315]	[268]	0	hSpCas9	negative selection	11805697
35871328	35871351	19	+	28162770	MV411	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	0.45179604928896155	[91]	[105]	4	hSpCas9	negative selection	11805698
35872536	35872559	19	+	28162770	MV411	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	-0.6821731213258269	[119]	[62]	-5	hSpCas9	negative selection	11805699
35872565	35872588	19	+	28162770	MV411	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-0.9896016465180737	[32]	[13]	-6	hSpCas9	negative selection	11805700
35874778	35874801	19	+	28162770	MONOMAC1	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	0.481035058053084	[159]	[255]	5	hSpCas9	negative selection	11975057
35874577	35874600	19	-	28162770	MONOMAC1	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-0.2921940800998939	[46]	[43]	-3	hSpCas9	negative selection	11975058
35868653	35868676	19	-	28162770	MONOMAC1	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-0.24010556895143964	[67]	[65]	-2	hSpCas9	negative selection	11975059
35869735	35869758	19	-	28162770	MONOMAC1	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	0.6516391346036691	[235]	[424]	6	hSpCas9	negative selection	11975060
35870942	35870965	19	-	28162770	MONOMAC1	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	0.8976000270785214	[58]	[125]	8	hSpCas9	negative selection	11975061
35870997	35871020	19	-	28162770	MONOMAC1	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	1.0659975587742399	[14]	[35]	8	hSpCas9	negative selection	11975062
35871309	35871332	19	+	28162770	MONOMAC1	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.3573102864235185	[253]	[372]	3	hSpCas9	negative selection	11975063
35871328	35871351	19	+	28162770	MONOMAC1	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-0.355734593078612	[47]	[42]	-3	hSpCas9	negative selection	11975064
35872536	35872559	19	+	28162770	MONOMAC1	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	0.6774322708565875	[53]	[98]	6	hSpCas9	negative selection	11975065
35872565	35872588	19	+	28162770	MONOMAC1	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-3.656468465696851	[21]	[1]	-9	hSpCas9	negative selection	11975066
35874778	35874801	19	+	28162770	OCIAML2	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	-0.8605763435581745	[56]	[173]	-6	hSpCas9	negative selection	12144423
35874577	35874600	19	-	28162770	OCIAML2	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	0.29875724661642256	[10]	[74]	3	hSpCas9	negative selection	12144424
35868653	35868676	19	-	28162770	OCIAML2	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-0.3648351612195645	[22]	[98]	-3	hSpCas9	negative selection	12144425
35869735	35869758	19	-	28162770	OCIAML2	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	-0.6568486340251241	[63]	[224]	-5	hSpCas9	negative selection	12144426
35870942	35870965	19	-	28162770	OCIAML2	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	0.07956725731831815	[13]	[81]	0	hSpCas9	negative selection	12144427
35870997	35871020	19	-	28162770	OCIAML2	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	1.261174063808266	[6]	[92]	9	hSpCas9	negative selection	12144428
35871309	35871332	19	+	28162770	OCIAML2	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	0.25183619922892986	[64]	[428]	2	hSpCas9	negative selection	12144429
35871328	35871351	19	+	28162770	OCIAML2	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	0.3367250968154428	[15]	[111]	3	hSpCas9	negative selection	12144430
35872536	35872559	19	+	28162770	OCIAML2	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	-0.06254508660508451	[12]	[68]	0	hSpCas9	negative selection	12144431
35872565	35872588	19	+	28162770	OCIAML2	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	-2.6405548266844736	[8]	[7]	-9	hSpCas9	negative selection	12144432
35874778	35874801	19	+	28162770	OCIAML3	viability	GTGCGGAGCAGAAGGAACAGAGG	APLP1	ENSG00000105290	1.0066877866615895	[75]	[460]	8	hSpCas9	negative selection	12313789
35874577	35874600	19	-	28162770	OCIAML3	viability	GATAAGGGCGATGACGCGGGTGG	APLP1	ENSG00000105290	-1.0376142917997777	[33]	[49]	-6	hSpCas9	negative selection	12313790
35868653	35868676	19	-	28162770	OCIAML3	viability	GCGACTTAGACCGCGAGCAGCGG	APLP1	ENSG00000105290	-1.009045139603007	[35]	[53]	-6	hSpCas9	negative selection	12313791
35869735	35869758	19	-	28162770	OCIAML3	viability	GCTGTGGGTCTGGTTCCCAGCGG	APLP1	ENSG00000105290	0.4289291709529959	[77]	[316]	4	hSpCas9	negative selection	12313792
35870942	35870965	19	-	28162770	OCIAML3	viability	GCACCAGCGCTCCATGGGGATGG	APLP1	ENSG00000105290	-1.7408490286534344	[30]	[27]	-8	hSpCas9	negative selection	12313793
35870997	35871020	19	-	28162770	OCIAML3	viability	GGAAGGGCACAACCTGGTGGTGG	APLP1	ENSG00000105290	-0.30450102312917804	[17]	[43]	-2	hSpCas9	negative selection	12313794
35871309	35871332	19	+	28162770	OCIAML3	viability	AATGTGAGAGTTCAACCCGGAGG	APLP1	ENSG00000105290	-0.32347869794344497	[159]	[385]	-3	hSpCas9	negative selection	12313795
35871328	35871351	19	+	28162770	OCIAML3	viability	GAGGCATCAGGAGGCACAGGAGG	APLP1	ENSG00000105290	-0.719538522408022	[29]	[54]	-5	hSpCas9	negative selection	12313796
35872536	35872559	19	+	28162770	OCIAML3	viability	GGGGAAATCAGTGAGCACGAGGG	APLP1	ENSG00000105290	-0.3946988321007564	[26]	[61]	-3	hSpCas9	negative selection	12313797
35872565	35872588	19	+	28162770	OCIAML3	viability	GAGGGCCAAGATGGACCTGGAGG	APLP1	ENSG00000105290	1.8978454560055116	[3]	[44]	9	hSpCas9	negative selection	12313798