Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:9870
• Symbol:AREL1
• Description:apoptosis resistant E3 ubiquitin protein ligase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/AREL1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
74684506	74684529	14	+	26472758	Jiyoye	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	-0.6901218198490414	[275]	[128]	-5	hSpCas9	negative selection	8894
74676641	74676664	14	+	26472758	Jiyoye	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	0.9083695245344316	[64]	[91]	6	hSpCas9	negative selection	8895
74684456	74684479	14	+	26472758	Jiyoye	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	-0.025140109204805958	[111]	[82]	0	hSpCas9	negative selection	8896
74675740	74675763	14	-	26472758	Jiyoye	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	0.1085797904491348	[459]	[373]	0	hSpCas9	negative selection	8897
74675722	74675745	14	-	26472758	Jiyoye	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	0.4616231655282499	[25]	[26]	3	hSpCas9	negative selection	8898
74674054	74674077	14	+	26472758	Jiyoye	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.5690630638827676	[159]	[178]	4	hSpCas9	negative selection	8899
74673167	74673190	14	-	26472758	Jiyoye	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	-0.0445205883518186	[185]	[135]	0	hSpCas9	negative selection	8900
74663962	74663985	14	+	26472758	Jiyoye	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	0.6772645448736176	[33]	[40]	5	hSpCas9	negative selection	8901
74684572	74684595	14	-	26472758	Jiyoye	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	-0.1034397777552015	[103]	[72]	0	hSpCas9	negative selection	8902
74684480	74684503	14	-	26472758	Jiyoye	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.1247756508051483	[44]	[36]	1	hSpCas9	negative selection	8903
74684506	74684529	14	+	26472758	KBM7	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.6205966454382847	[683,351]	[391,338]	6	hSpCas9	negative selection	200012
74676641	74676664	14	+	26472758	KBM7	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	-0.22997679815288244	[429,516]	[172,209]	-2	hSpCas9	negative selection	200013
74684456	74684479	14	+	26472758	KBM7	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.7560164113189989	[551,468]	[413,394]	8	hSpCas9	negative selection	200014
74675740	74675763	14	-	26472758	KBM7	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	-0.42788858698800913	[1725,1439]	[562,539]	-4	hSpCas9	negative selection	200015
74675722	74675745	14	-	26472758	KBM7	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	-0.12618393828840646	[313,146]	[112,80]	-1	hSpCas9	negative selection	200016
74674054	74674077	14	+	26472758	KBM7	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.3868484874938429	[851,418]	[350,403]	4	hSpCas9	negative selection	200017
74673167	74673190	14	-	26472758	KBM7	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.45720454756119844	[744,779]	[575,423]	5	hSpCas9	negative selection	200018
74663962	74663985	14	+	26472758	KBM7	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	-0.26814559746983757	[327,246]	[154,71]	-3	hSpCas9	negative selection	200019
74684572	74684595	14	-	26472758	KBM7	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	0.9849011403951284	[391,271]	[318,291]	9	hSpCas9	negative selection	200020
74684480	74684503	14	-	26472758	KBM7	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.027462170103098593	[354,254]	[126,159]	0	hSpCas9	negative selection	200021
74684506	74684529	14	+	26472758	Raji	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.12249042776380786	[284]	[71]	1	hSpCas9	negative selection	391130
74676641	74676664	14	+	26472758	Raji	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	0.3357997443378175	[238]	[69]	3	hSpCas9	negative selection	391131
74684456	74684479	14	+	26472758	Raji	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	-0.5029345396244511	[286]	[46]	-4	hSpCas9	negative selection	391132
74675740	74675763	14	-	26472758	Raji	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	0.6896569485671156	[536]	[200]	6	hSpCas9	negative selection	391133
74675722	74675745	14	-	26472758	Raji	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	0.8653087481754518	[122]	[51]	7	hSpCas9	negative selection	391134
74674054	74674077	14	+	26472758	Raji	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-0.5603193963554931	[304]	[47]	-4	hSpCas9	negative selection	391135
74673167	74673190	14	-	26472758	Raji	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.3018536547243219	[394]	[112]	3	hSpCas9	negative selection	391136
74663962	74663985	14	+	26472758	Raji	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	-0.3188812193284986	[171]	[31]	-3	hSpCas9	negative selection	391137
74684572	74684595	14	-	26472758	Raji	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	-0.9064222641514309	[314]	[38]	-6	hSpCas9	negative selection	391138
74684480	74684503	14	-	26472758	Raji	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	-0.2566700351864395	[138]	[26]	-2	hSpCas9	negative selection	391139
74684506	74684529	14	+	26472758	K562	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.5934263566100935	[474]	[604]	5	hSpCas9	negative selection	582248
74676641	74676664	14	+	26472758	K562	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	-0.13734261673809828	[399]	[306]	-1	hSpCas9	negative selection	582249
74684456	74684479	14	+	26472758	K562	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.023773968616266128	[549]	[471]	0	hSpCas9	negative selection	582250
74675740	74675763	14	-	26472758	K562	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	-0.47040058054135825	[1335]	[813]	-3	hSpCas9	negative selection	582251
74675722	74675745	14	-	26472758	K562	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	0.0876932239789937	[203]	[182]	0	hSpCas9	negative selection	582252
74674054	74674077	14	+	26472758	K562	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.14698457676082033	[489]	[457]	1	hSpCas9	negative selection	582253
74673167	74673190	14	-	26472758	K562	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	1.0034106281626518	[662]	[1121]	8	hSpCas9	negative selection	582254
74663962	74663985	14	+	26472758	K562	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	0.34245081062697347	[255]	[273]	2	hSpCas9	negative selection	582255
74684572	74684595	14	-	26472758	K562	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	0.7650465866354794	[213]	[306]	6	hSpCas9	negative selection	582256
74684480	74684503	14	-	26472758	K562	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	-0.38501840219531414	[279]	[180]	-3	hSpCas9	negative selection	582257
74673127	74673150	14	+	26627737	DLD1	viability	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-0.535985657323087	[280]	[23,72,81]	-5	hSpCas9	negative selection	789366
74674054	74674077	14	+	26627737	DLD1	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.8379616635401566	[67]	[10,58,43]	7	hSpCas9	negative selection	789367
74675782	74675805	14	-	26627737	DLD1	viability	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-0.408513095125902	[556]	[93,185,117]	-4	hSpCas9	negative selection	789368
74676673	74676696	14	+	26627737	DLD1	viability	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	0.5425385423976574	[72]	[49,50,3]	5	hSpCas9	negative selection	789369
74683472	74683495	14	+	26627737	DLD1	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.09643513370263124	[174]	[133,37,9]	1	hSpCas9	negative selection	789370
74684612	74684635	14	+	26627737	DLD1	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	1.110243050695701	[420]	[220,307,318]	8	hSpCas9	negative selection	789371
74673127	74673150	14	+	26627737	GBM cells	viability after 5 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-1.697730430883106	[247]	[42,38]	-9	hSpCas9	negative selection	871681
74674054	74674077	14	+	26627737	GBM cells	viability after 5 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.4450405263316755	[98]	[22,15]	-9	hSpCas9	negative selection	871682
74675782	74675805	14	-	26627737	GBM cells	viability after 5 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-0.27368923209806795	[336]	[146,151]	-4	hSpCas9	negative selection	871683
74676673	74676696	14	+	26627737	GBM cells	viability after 5 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.664987010307641	[101]	[38,29]	-8	hSpCas9	negative selection	871684
74683472	74683495	14	+	26627737	GBM cells	viability after 5 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.5095021832823364	[92]	[88,52]	7	hSpCas9	negative selection	871685
74684612	74684635	14	+	26627737	GBM cells	viability after 5 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.5225154028549015	[306]	[241,230]	7	hSpCas9	negative selection	871686
74673127	74673150	14	+	26627737	GBM cells	viability after 13 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-1.2487259467621925	[247]	[65,48]	-8	hSpCas9	negative selection	953996
74674054	74674077	14	+	26627737	GBM cells	viability after 13 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-0.18680826346969392	[98]	[87,13]	-2	hSpCas9	negative selection	953997
74675782	74675805	14	-	26627737	GBM cells	viability after 13 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-0.07399885771979614	[336]	[133,205]	-1	hSpCas9	negative selection	953998
74676673	74676696	14	+	26627737	GBM cells	viability after 13 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.3899450258203363	[101]	[28,52]	-5	hSpCas9	negative selection	953999
74683472	74683495	14	+	26627737	GBM cells	viability after 13 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.5281112561964465	[92]	[85,61]	6	hSpCas9	negative selection	954000
74684612	74684635	14	+	26627737	GBM cells	viability after 13 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.19754818104415545	[306]	[222,164]	2	hSpCas9	negative selection	954001
74673127	74673150	14	+	26627737	GBM cells	viability after 21 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-1.661181485432741	[247]	[51,33]	-8	hSpCas9	negative selection	1036311
74674054	74674077	14	+	26627737	GBM cells	viability after 21 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.579198319021639	[98]	[17,17]	-8	hSpCas9	negative selection	1036312
74675782	74675805	14	-	26627737	GBM cells	viability after 21 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-0.39259494092777736	[336]	[151,127]	-4	hSpCas9	negative selection	1036313
74676673	74676696	14	+	26627737	GBM cells	viability after 21 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-2.708505891850982	[101]	[8,7]	-9	hSpCas9	negative selection	1036314
74683472	74683495	14	+	26627737	GBM cells	viability after 21 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.7708764029630055	[92]	[92,79]	7	hSpCas9	negative selection	1036315
74684612	74684635	14	+	26627737	GBM cells	viability after 21 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.18524575935149507	[306]	[153,139]	-2	hSpCas9	negative selection	1036316
74673127	74673150	14	+	26627737	RPE1	viability after 9 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	0.9043723281599476	[85]	[28,77]	6	hSpCas9	negative selection	1118626
74674054	74674077	14	+	26627737	RPE1	viability after 9 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-0.6085258473688391	[260]	[67,34]	-4	hSpCas9	negative selection	1118627
74675782	74675805	14	-	26627737	RPE1	viability after 9 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-0.10808004836745722	[687]	[277,98]	-1	hSpCas9	negative selection	1118628
74676673	74676696	14	+	26627737	RPE1	viability after 9 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-1.2380593868431982	[136]	[15,20]	-7	hSpCas9	negative selection	1118629
74683472	74683495	14	+	26627737	RPE1	viability after 9 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.3247867168841412	[374]	[136,159]	2	hSpCas9	negative selection	1118630
74684612	74684635	14	+	26627737	RPE1	viability after 9 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.3291655427521101	[1140]	[484,401]	2	hSpCas9	negative selection	1118631
74673127	74673150	14	+	26627737	RPE1	viability after 12 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	0.8223630716918251	[85]	[18,63]	5	hSpCas9	negative selection	1200941
74674054	74674077	14	+	26627737	RPE1	viability after 12 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-0.8119289564662766	[260]	[37,41]	-5	hSpCas9	negative selection	1200942
74675782	74675805	14	-	26627737	RPE1	viability after 12 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.48713231576685945	[687]	[312,201]	3	hSpCas9	negative selection	1200943
74676673	74676696	14	+	26627737	RPE1	viability after 12 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.33120368823235546	[136]	[37,19]	-2	hSpCas9	negative selection	1200944
74683472	74683495	14	+	26627737	RPE1	viability after 12 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.6793196370907031	[374]	[110,11]	-5	hSpCas9	negative selection	1200945
74684612	74684635	14	+	26627737	RPE1	viability after 12 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.7378529927164797	[1140]	[501,520]	5	hSpCas9	negative selection	1200946
74673127	74673150	14	+	26627737	RPE1	viability after 15 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	0.06008021747115366	[85]	[4,44]	0	hSpCas9	negative selection	1283256
74674054	74674077	14	+	26627737	RPE1	viability after 15 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.076128237807813	[260]	[33,35]	-6	hSpCas9	negative selection	1283257
74675782	74675805	14	-	26627737	RPE1	viability after 15 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	1.4352281844996038	[687]	[874,189]	7	hSpCas9	negative selection	1283258
74676673	74676696	14	+	26627737	RPE1	viability after 15 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	1.3406231768405115	[136]	[145,51]	7	hSpCas9	negative selection	1283259
74683472	74683495	14	+	26627737	RPE1	viability after 15 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-1.1303643229736395	[374]	[78,18]	-6	hSpCas9	negative selection	1283260
74684612	74684635	14	+	26627737	RPE1	viability after 15 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.30813411323369466	[1140]	[364,432]	2	hSpCas9	negative selection	1283261
74673127	74673150	14	+	26627737	RPE1	viability after 18 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	0.39514928969343854	[85]	[1,60]	2	hSpCas9	negative selection	1365571
74674054	74674077	14	+	26627737	RPE1	viability after 18 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-2.3343055800523267	[260]	[12,14]	-8	hSpCas9	negative selection	1365572
74675782	74675805	14	-	26627737	RPE1	viability after 18 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.9954870163015108	[687]	[389,348]	6	hSpCas9	negative selection	1365573
74676673	74676696	14	+	26627737	RPE1	viability after 18 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.22707385159063342	[136]	[4,59]	-1	hSpCas9	negative selection	1365574
74683472	74683495	14	+	26627737	RPE1	viability after 18 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.37331144743193634	[374]	[110,42]	-2	hSpCas9	negative selection	1365575
74684612	74684635	14	+	26627737	RPE1	viability after 18 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.8588456153537166	[1140]	[716,388]	5	hSpCas9	negative selection	1365576
74673127	74673150	14	+	26627737	HeLa	viability after 8 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	0.2482603476259183	[169]	[141,52,80]	2	hSpCas9	negative selection	1447886
74674054	74674077	14	+	26627737	HeLa	viability after 8 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.5100275202115534	[341]	[24,91,34]	-9	hSpCas9	negative selection	1447887
74675782	74675805	14	-	26627737	HeLa	viability after 8 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-1.2441857431537446	[588]	[156,94,84]	-8	hSpCas9	negative selection	1447888
74676673	74676696	14	+	26627737	HeLa	viability after 8 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.49797495233176026	[84]	[55,0,27]	-5	hSpCas9	negative selection	1447889
74683472	74683495	14	+	26627737	HeLa	viability after 8 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.30335502645809126	[284]	[119,132,55]	-3	hSpCas9	negative selection	1447890
74684612	74684635	14	+	26627737	HeLa	viability after 8 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.9731264758398923	[337]	[356,202,318]	7	hSpCas9	negative selection	1447891
74673127	74673150	14	+	26627737	HeLa	viability after 12 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	0.9104492911961404	[169]	[131,142,119]	7	hSpCas9	negative selection	1530201
74674054	74674077	14	+	26627737	HeLa	viability after 12 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.1348415695992895	[341]	[131,45,18]	-8	hSpCas9	negative selection	1530202
74675782	74675805	14	-	26627737	HeLa	viability after 12 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-0.3273778873568699	[588]	[120,305,140]	-3	hSpCas9	negative selection	1530203
74676673	74676696	14	+	26627737	HeLa	viability after 12 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-1.9416352886705925	[84]	[0,10,14]	-9	hSpCas9	negative selection	1530204
74683472	74683495	14	+	26627737	HeLa	viability after 12 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-1.0042000136950775	[284]	[13,113,40]	-7	hSpCas9	negative selection	1530205
74684612	74684635	14	+	26627737	HeLa	viability after 12 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.7504409387257187	[337]	[106,293,293]	6	hSpCas9	negative selection	1530206
74673127	74673150	14	+	26627737	HeLa	viability after 15 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	1.531075742667024	[169]	[144,312,137]	8	hSpCas9	negative selection	1612516
74674054	74674077	14	+	26627737	HeLa	viability after 15 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.2466765530264174	[341]	[38,93,41]	-8	hSpCas9	negative selection	1612517
74675782	74675805	14	-	26627737	HeLa	viability after 15 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.27832544728211395	[588]	[251,304,317]	2	hSpCas9	negative selection	1612518
74676673	74676696	14	+	26627737	HeLa	viability after 15 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-1.6395681830881466	[84]	[10,2,19]	-8	hSpCas9	negative selection	1612519
74683472	74683495	14	+	26627737	HeLa	viability after 15 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.7597800490302529	[284]	[66,52,86]	-6	hSpCas9	negative selection	1612520
74684612	74684635	14	+	26627737	HeLa	viability after 15 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.9947462568517236	[337]	[183,241,407]	7	hSpCas9	negative selection	1612521
74673127	74673150	14	+	26627737	HeLa	viability after 18 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	1.5442614884424817	[169]	[100,258,137]	8	hSpCas9	negative selection	1694831
74674054	74674077	14	+	26627737	HeLa	viability after 18 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.2907681660552164	[341]	[24,74,41]	-8	hSpCas9	negative selection	1694832
74675782	74675805	14	-	26627737	HeLa	viability after 18 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.2795438238307394	[588]	[161,261,317]	2	hSpCas9	negative selection	1694833
74676673	74676696	14	+	26627737	HeLa	viability after 18 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-1.6241512765537038	[84]	[7,1,19]	-8	hSpCas9	negative selection	1694834
74683472	74683495	14	+	26627737	HeLa	viability after 18 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.6681823540689946	[284]	[51,45,86]	-5	hSpCas9	negative selection	1694835
74684612	74684635	14	+	26627737	HeLa	viability after 18 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	1.0290556681898675	[337]	[130,206,407]	7	hSpCas9	negative selection	1694836
74673127	74673150	14	+	26627737	HCT116	viability after 6 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	1.3951283891927995	[213]	[121,69]	7	hSpCas9	negative selection	1777146
74674054	74674077	14	+	26627737	HCT116	viability after 6 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-2.0065088153457227	[606]	[64,0]	-8	hSpCas9	negative selection	1777147
74675782	74675805	14	-	26627737	HCT116	viability after 6 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-0.5848278344742112	[767]	[162,34]	-3	hSpCas9	negative selection	1777148
74676673	74676696	14	+	26627737	HCT116	viability after 6 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-2.509393262916245	[131]	[2,3]	-8	hSpCas9	negative selection	1777149
74683472	74683495	14	+	26627737	HCT116	viability after 6 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-1.6889210220006483	[287]	[24,7]	-7	hSpCas9	negative selection	1777150
74684612	74684635	14	+	26627737	HCT116	viability after 6 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.9261217366759009	[638]	[235,165]	5	hSpCas9	negative selection	1777151
74673127	74673150	14	+	26627737	HCT116	viability after 8 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-0.6101715840880242	[175]	[113,54,22]	-6	hSpCas9	negative selection	1859461
74674054	74674077	14	+	26627737	HCT116	viability after 8 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.5068602676785114	[278]	[41,59,59]	-9	hSpCas9	negative selection	1859462
74675782	74675805	14	-	26627737	HCT116	viability after 8 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-0.2687924577452115	[456]	[191,164,268]	-3	hSpCas9	negative selection	1859463
74676673	74676696	14	+	26627737	HCT116	viability after 8 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.4375751479537333	[77]	[18,45,29]	-5	hSpCas9	negative selection	1859464
74683472	74683495	14	+	26627737	HCT116	viability after 8 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.9703329773126819	[79]	[79,92,85]	8	hSpCas9	negative selection	1859465
74684612	74684635	14	+	26627737	HCT116	viability after 8 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.13343134007946172	[462]	[206,314,175]	-1	hSpCas9	negative selection	1859466
74673127	74673150	14	+	26627737	HCT116	viability after 9 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-0.35389630210066403	[213]	[56,34]	-2	hSpCas9	negative selection	1941776
74674054	74674077	14	+	26627737	HCT116	viability after 9 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-4.378422438728232	[606]	[4,9]	-9	hSpCas9	negative selection	1941777
74675782	74675805	14	-	26627737	HCT116	viability after 9 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-0.48552638293434536	[767]	[203,100]	-3	hSpCas9	negative selection	1941778
74676673	74676696	14	+	26627737	HCT116	viability after 9 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	0.2054113963642621	[131]	[24,52]	1	hSpCas9	negative selection	1941779
74683472	74683495	14	+	26627737	HCT116	viability after 9 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.12195652098884757	[287]	[38,118]	0	hSpCas9	negative selection	1941780
74684612	74684635	14	+	26627737	HCT116	viability after 9 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.8969330612185079	[638]	[534,145]	6	hSpCas9	negative selection	1941781
74673127	74673150	14	+	26627737	HCT116	viability after 12 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	0.21865950088139186	[175]	[96,114,111]	2	hSpCas9	negative selection	2024091
74674054	74674077	14	+	26627737	HCT116	viability after 12 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.460417259789638	[278]	[74,55,26]	-9	hSpCas9	negative selection	2024092
74675782	74675805	14	-	26627737	HCT116	viability after 12 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.5007773509658309	[456]	[597,223,171]	5	hSpCas9	negative selection	2024093
74676673	74676696	14	+	26627737	HCT116	viability after 12 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.22670889662788762	[77]	[67,26,6]	-2	hSpCas9	negative selection	2024094
74683472	74683495	14	+	26627737	HCT116	viability after 12 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.7407543851087262	[79]	[52,99,59]	6	hSpCas9	negative selection	2024095
74684612	74684635	14	+	26627737	HCT116	viability after 12 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.08150727733289398	[462]	[171,261,345]	0	hSpCas9	negative selection	2024096
74673127	74673150	14	+	26627737	HCT116	viability after 15 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-0.009003565054685914	[175]	[97,98,103]	0	hSpCas9	negative selection	2106406
74674054	74674077	14	+	26627737	HCT116	viability after 15 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.0910536902546375	[278]	[109,54,64]	-8	hSpCas9	negative selection	2106407
74675782	74675805	14	-	26627737	HCT116	viability after 15 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.43393181909859857	[456]	[323,303,430]	4	hSpCas9	negative selection	2106408
74676673	74676696	14	+	26627737	HCT116	viability after 15 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.5062510083732572	[77]	[6,83,0]	-5	hSpCas9	negative selection	2106409
74683472	74683495	14	+	26627737	HCT116	viability after 15 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	1.05893069991208	[79]	[58,70,151]	8	hSpCas9	negative selection	2106410
74684612	74684635	14	+	26627737	HCT116	viability after 15 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.18777386740946161	[462]	[194,294,205]	-2	hSpCas9	negative selection	2106411
74673127	74673150	14	+	26627737	HCT116	viability after 18 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-0.9006130176978864	[175]	[31,65,36]	-7	hSpCas9	negative selection	2188721
74674054	74674077	14	+	26627737	HCT116	viability after 18 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-1.3319962753329344	[278]	[69,35,55]	-8	hSpCas9	negative selection	2188722
74675782	74675805	14	-	26627737	HCT116	viability after 18 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.39148644157723655	[456]	[237,194,449]	3	hSpCas9	negative selection	2188723
74676673	74676696	14	+	26627737	HCT116	viability after 18 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-1.7209730427994911	[77]	[7,6,19]	-8	hSpCas9	negative selection	2188724
74683472	74683495	14	+	26627737	HCT116	viability after 18 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	1.0898188021147979	[79]	[20,149,70]	8	hSpCas9	negative selection	2188725
74684612	74684635	14	+	26627737	HCT116	viability after 18 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.1290870826997697	[462]	[159,171,287]	-1	hSpCas9	negative selection	2188726
74660317	74660340	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCGCTCTGTCACCCAGGCTAG	AREL1	ENSG00000119682	-1.0560306979191085	[78,130]	[14,5]	-6	dCas9-VP64	positive selection	2386543
74713052	74713075	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACCCGGCCTGGGAACCGGCTCGG	AREL1	ENSG00000119682	1.2204084521021512	[8,256]	[7,134]	5	dCas9-VP64	positive selection	2446854
74713027	74713050	14	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGACCAACTCTGGGGTCTGTTGG	AREL1	ENSG00000119682	0.09513839354245668	[36,60]	[3,18]	0	dCas9-VP64	positive selection	2446855
74712989	74713012	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGCACTCAGCAGAAGACGGG	AREL1	ENSG00000119682	0.41318876168660856	[248,115]	[76,26]	1	dCas9-VP64	positive selection	2446856
74699373	74699396	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGAGAGAGAGAGAGAGAGAG	AREL1	ENSG00000119682	3.246472249107505	[0,4]	[1,12]	8	dCas9-VP64	positive selection	2458444
74660317	74660340	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCGCTCTGTCACCCAGGCTAG	AREL1	ENSG00000119682	0.7674335835704862	[415,371]	[130,301]	5	dCas9-VP64	positive selection	2481798
74713052	74713075	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACCCGGCCTGGGAACCGGCTCGG	AREL1	ENSG00000119682	0.6751182433718633	[115,72]	[25,71]	5	dCas9-VP64	positive selection	2542109
74713027	74713050	14	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGACCAACTCTGGGGTCTGTTGG	AREL1	ENSG00000119682	-1.1803216454708925	[148,127]	[14,22]	-9	dCas9-VP64	positive selection	2542110
74712989	74713012	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGCACTCAGCAGAAGACGGG	AREL1	ENSG00000119682	2.4980676589148825	[144,183]	[76,516]	9	dCas9-VP64	positive selection	2542111
74699373	74699396	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGAGAGAGAGAGAGAGAGAG	AREL1	ENSG00000119682	2.8702956375825326	[127,55]	[142,294]	9	dCas9-VP64	positive selection	2553699
74684542	74684565	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.19113707699634255	[3,3]	[4,2]	4	hSpCas9	positive selection	2971164
74684507	74684530	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	-0.12026340765248908	[3,2]	[0,3]	-2	hSpCas9	positive selection	2971165
74675698	74675721	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.15294944319002413	[4,4]	[4,4]	3	hSpCas9	positive selection	2971166
74673131	74673154	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTACAGCTGAGCTCCACAGGAGG	AREL1	ENSG00000119682	0.1560673138057807	[3,3]	[3,3]	3	hSpCas9	positive selection	2971167
74684542	74684565	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.361057770313865	[3,3]	[4,2]	6	hSpCas9	positive selection	3039022
74684507	74684530	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	-0.24628695399607026	[3,3]	[2,0]	-4	hSpCas9	positive selection	3039023
74675698	74675721	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.024519243606048347	[4,4]	[3,2]	0	hSpCas9	positive selection	3039024
74673131	74673154	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTACAGCTGAGCTCCACAGGAGG	AREL1	ENSG00000119682	-0.2293069625518859	[3,3]	[1,1]	-3	hSpCas9	positive selection	3039025
74675891	74675914	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	1.290109372599988	[71,52]	[0,0]	5	hSpCas9	positive selection	3337186
74675698	74675721	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.6279695913662254	[98,98]	[0,0]	3	hSpCas9	positive selection	3356432
74683472	74683495	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.7337642553888224	[91,91]	[0,0]	3	hSpCas9	positive selection	3356433
74675709	74675732	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.6374915518621085	[237,237]	[0,0]	-4	hSpCas9	positive selection	3356434
74684542	74684565	14	-	26780180	HT29	viability (Avana library 4 designs)	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	1.33006799075672	[]	[]	5	hSpCas9	negative selection	3407276
74684506	74684529	14	+	26780180	HT29	viability (Avana library 4 designs)	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	1.86473878325505	[]	[]	7	hSpCas9	negative selection	3407277
74675698	74675721	14	-	26780180	HT29	viability (Avana library 4 designs)	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.0338876996276156	[]	[]	0	hSpCas9	negative selection	3407278
74673130	74673153	14	+	26780180	HT29	viability (Avana library 4 designs)	TTACAGCTGAGCTCCACAGGAGG	AREL1	ENSG00000119682	1.50340544149979	[]	[]	6	hSpCas9	negative selection	3407279
74684506	74684529	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	3.27087024492683	[]	[]	5	hSpCas9	negative selection	3480241
74673130	74673153	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACAGCTGAGCTCCACAGGAGG	AREL1	ENSG00000119682	-2.74475330676483	[]	[]	-3	hSpCas9	negative selection	3480242
74684542	74684565	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	2.13077463904382	[]	[]	3	hSpCas9	negative selection	3480243
74675698	74675721	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.784832640480415	[]	[]	-1	hSpCas9	negative selection	3480244
74676577	74676600	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTACCTCATGAATGGACAAGG	AREL1	ENSG00000119682	-0.957351031800536	[]	[]	-1	hSpCas9	negative selection	3480245
74684598	74684621	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGAAGCTGACTACACGTGCGG	AREL1	ENSG00000119682	2.98879332940695	[]	[]	4	hSpCas9	negative selection	3480246
74684506	74684529	14	+	26780180	A375	viability (Avana lentiGuide)	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	-2.55298934992068	[]	[]	-4	hSpCas9	negative selection	3588900
74673130	74673153	14	+	26780180	A375	viability (Avana lentiGuide)	TTACAGCTGAGCTCCACAGGAGG	AREL1	ENSG00000119682	16.187647319943	[]	[]	8	hSpCas9	negative selection	3588901
74684542	74684565	14	-	26780180	A375	viability (Avana lentiGuide)	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	3.53211965560267	[]	[]	3	hSpCas9	negative selection	3588902
74675698	74675721	14	-	26780180	A375	viability (Avana lentiGuide)	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-2.03609028183167	[]	[]	-3	hSpCas9	negative selection	3588903
74676577	74676600	14	+	26780180	A375	viability (Avana lentiGuide)	GCTTACCTCATGAATGGACAAGG	AREL1	ENSG00000119682	-1.2878212538796	[]	[]	-2	hSpCas9	negative selection	3588904
74684598	74684621	14	+	26780180	A375	viability (Avana lentiGuide)	GAGGAAGCTGACTACACGTGCGG	AREL1	ENSG00000119682	-4.50372559266059	[]	[]	-7	hSpCas9	negative selection	3588905
74684506	74684529	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.192987710731425	[4]	[5,5]	5	hSpCas9	positive selection	3697559
74673130	74673153	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACAGCTGAGCTCCACAGGAGG	AREL1	ENSG00000119682	-0.4492839361073979	[4]	[4,1]	-6	hSpCas9	positive selection	3697560
74684542	74684565	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.012146072005546182	[6]	[6,5]	0	hSpCas9	positive selection	3697561
74675698	74675721	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.01145105389007689	[6]	[6,6]	0	hSpCas9	positive selection	3697562
74676577	74676600	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTACCTCATGAATGGACAAGG	AREL1	ENSG00000119682	-0.02829167090877293	[5]	[4,4]	0	hSpCas9	positive selection	3697563
74684598	74684621	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGAAGCTGACTACACGTGCGG	AREL1	ENSG00000119682	0.3245426602275048	[4]	[5,5]	8	hSpCas9	positive selection	3697564
74684506	74684529	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.03349839975959715	[4]	[2,4]	0	hSpCas9	positive selection	3806166
74673130	74673153	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACAGCTGAGCTCCACAGGAGG	AREL1	ENSG00000119682	-1.607830626725777	[5]	[1,0]	-9	hSpCas9	positive selection	3806167
74684542	74684565	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.02759249954688764	[6]	[5,5]	0	hSpCas9	positive selection	3806168
74675698	74675721	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.35662912080497644	[6]	[6,6]	9	hSpCas9	positive selection	3806169
74676577	74676600	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTACCTCATGAATGGACAAGG	AREL1	ENSG00000119682	0.2875474687190921	[5]	[5,5]	7	hSpCas9	positive selection	3806170
74684598	74684621	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGAAGCTGACTACACGTGCGG	AREL1	ENSG00000119682	0.14871700287860362	[5]	[5,4]	3	hSpCas9	positive selection	3806171
74675709	74675732	14	+	26780180	A375	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.741320910125214	[]	[]	2	hSpCas9	negative selection	3914428
74684542	74684565	14	-	26780180	A375	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.504407030064527	[]	[]	1	hSpCas9	negative selection	3914429
74692293	74692316	14	+	26780180	A375	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	1.1062792067786	[]	[]	5	hSpCas9	negative selection	3914430
74683472	74683495	14	+	26780180	A375	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	1.37138236438697	[]	[]	7	hSpCas9	negative selection	3914431
74683392	74683415	14	-	26780180	A375	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.793278416190553	[]	[]	3	hSpCas9	negative selection	3914432
74683392	74683415	14	-	26780180	A375	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.793278416190553	[]	[]	3	hSpCas9	negative selection	3914433
74684612	74684635	14	+	26780180	A375	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.59080906567175	[]	[]	1	hSpCas9	negative selection	3914434
74683449	74683472	14	-	26780180	A375	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.517965672270495	[]	[]	1	hSpCas9	negative selection	3914435
74683449	74683472	14	-	26780180	A375	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.517965672270495	[]	[]	1	hSpCas9	negative selection	3914436
74692255	74692278	14	+	26780180	A375	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	1.11181746862474	[]	[]	5	hSpCas9	negative selection	3914437
74675891	74675914	14	+	26780180	A375	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	1.24283981743442	[]	[]	6	hSpCas9	negative selection	3914438
74675698	74675721	14	-	26780180	A375	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	1.13560443722532	[]	[]	6	hSpCas9	negative selection	3914439
74675709	74675732	14	+	26780180	HT29	viability (GeCKOv2 library)	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	1.43741140148864	[]	[]	7	hSpCas9	negative selection	4022394
74684542	74684565	14	-	26780180	HT29	viability (GeCKOv2 library)	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.833314300683366	[]	[]	3	hSpCas9	negative selection	4022395
74692293	74692316	14	+	26780180	HT29	viability (GeCKOv2 library)	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.979671852505916	[]	[]	4	hSpCas9	negative selection	4022396
74683472	74683495	14	+	26780180	HT29	viability (GeCKOv2 library)	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	1.83479989638387	[]	[]	8	hSpCas9	negative selection	4022397
74683392	74683415	14	-	26780180	HT29	viability (GeCKOv2 library)	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.685695004391694	[]	[]	2	hSpCas9	negative selection	4022398
74683392	74683415	14	-	26780180	HT29	viability (GeCKOv2 library)	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.685695004391694	[]	[]	2	hSpCas9	negative selection	4022399
74684612	74684635	14	+	26780180	HT29	viability (GeCKOv2 library)	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.73405637688611	[]	[]	3	hSpCas9	negative selection	4022400
74683449	74683472	14	-	26780180	HT29	viability (GeCKOv2 library)	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.264323729661578	[]	[]	0	hSpCas9	negative selection	4022401
74683449	74683472	14	-	26780180	HT29	viability (GeCKOv2 library)	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.264323729661578	[]	[]	0	hSpCas9	negative selection	4022402
74692255	74692278	14	+	26780180	HT29	viability (GeCKOv2 library)	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	2.26048917598525	[]	[]	9	hSpCas9	negative selection	4022403
74675891	74675914	14	+	26780180	HT29	viability (GeCKOv2 library)	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	0.795186133863745	[]	[]	3	hSpCas9	negative selection	4022404
74675698	74675721	14	-	26780180	HT29	viability (GeCKOv2 library)	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.68852891228592	[]	[]	2	hSpCas9	negative selection	4022405
74683472	74683495	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.28644619195426874	[3]	[2,2]	7	hSpCas9	positive selection	4146663
74683392	74683415	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.08027936799763236	[1]	[1,0]	-2	hSpCas9	positive selection	4146664
74685599	74685622	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACCTGATGTTTTACGTTATTGG	AREL1	ENSG00000119682	0.017279625092718853	[3]	[2,2]	0	hSpCas9	positive selection	4146666
74683472	74683495	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.30763954627389706	[3]	[1,2,5,0]	2	hSpCas9	positive selection	4210685
74683392	74683415	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.2622332738348659	[3]	[3,0,0,0]	-4	hSpCas9	positive selection	4210686
74685599	74685622	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACCTGATGTTTTACGTTATTGG	AREL1	ENSG00000119682	0.2504582396027958	[4]	[2,2,4,0]	2	hSpCas9	positive selection	4210688
74683449	74683472	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.5516053565929642	[3]	[4,4]	9	hSpCas9	positive selection	4256344
74675891	74675914	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	0.09053987361045188	[2]	[3,1]	1	hSpCas9	positive selection	4256345
74683392	74683415	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.22086813216744974	[2]	[2,1]	4	hSpCas9	positive selection	4256346
74684542	74684565	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.21080901533087432	[3]	[1,1]	-4	hSpCas9	positive selection	4278295
74683449	74683472	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.5516053565929642	[3]	[4,4]	9	hSpCas9	positive selection	4278296
74684612	74684635	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.13590013480269325	[2]	[2,0]	-3	hSpCas9	positive selection	4278297
74675698	74675721	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.48900132354992815	[2]	[1,3]	8	hSpCas9	positive selection	4320628
74683472	74683495	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.258268253172383	[2]	[1,0]	-5	hSpCas9	positive selection	4320629
74675709	74675732	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.1935970022237694	[3]	[3,2]	4	hSpCas9	positive selection	4320630
74692293	74692316	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.18171958986200887	[3]	[2,2]	3	hSpCas9	positive selection	4342550
74683392	74683415	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.22086813216744974	[2]	[2,1]	4	hSpCas9	positive selection	4342551
74692255	74692278	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	-0.2361025492567192	[3]	[2,1]	-5	hSpCas9	positive selection	4342552
74675892	74675914	14	+	27760321	OCIAML3	viability	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.05573669328478767	[402,353]	[232,350]	0	hSpCas9	negative selection	4378965
74683394	74683416	14	+	27760321	OCIAML3	viability	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	0.03895142510385874	[71,66]	[77,26]	0	hSpCas9	negative selection	4378966
74683449	74683471	14	-	27760321	OCIAML3	viability	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.371632000665347	[483,440]	[442,499]	4	hSpCas9	negative selection	4378967
74684446	74684468	14	+	27760321	OCIAML3	viability	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	-0.07925168557937518	[347,296]	[194,293]	-1	hSpCas9	negative selection	4378968
74684542	74684564	14	-	27760321	OCIAML3	viability	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.10895598125026448	[546,555]	[404,396]	-1	hSpCas9	negative selection	4378969
74675892	74675914	14	+	27760321	OCIAML2	viability	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.642671425895077	[402,353]	[193,197]	-6	hSpCas9	negative selection	4462428
74683394	74683416	14	+	27760321	OCIAML2	viability	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	1.0796932176603773	[71,66]	[95,148]	9	hSpCas9	negative selection	4462429
74683449	74683471	14	-	27760321	OCIAML2	viability	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.5562086024736637	[483,440]	[529,575]	7	hSpCas9	negative selection	4462430
74684446	74684468	14	+	27760321	OCIAML2	viability	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	-0.3328576422141681	[347,296]	[199,214]	-4	hSpCas9	negative selection	4462431
74684542	74684564	14	-	27760321	OCIAML2	viability	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-1.221968121964861	[546,555]	[147,249]	-8	hSpCas9	negative selection	4462432
74675892	74675914	14	+	27760321	MV411	viability	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	0.42202804819727974	[402,353]	[54,752]	3	hSpCas9	negative selection	4545891
74683394	74683416	14	+	27760321	MV411	viability	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	-5.519740315250455	[71,66]	[0,0]	-9	hSpCas9	negative selection	4545892
74683449	74683471	14	-	27760321	MV411	viability	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.3206770413979436	[483,440]	[346,431]	2	hSpCas9	negative selection	4545893
74684446	74684468	14	+	27760321	MV411	viability	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	0.05597063041636663	[347,296]	[132,351]	0	hSpCas9	negative selection	4545894
74684542	74684564	14	-	27760321	MV411	viability	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.2745358315831477	[546,555]	[391,516]	2	hSpCas9	negative selection	4545895
74675892	74675914	14	+	27760321	HL60	viability	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	1.0912852952061607	[402,353]	[621,694]	9	hSpCas9	negative selection	4629354
74683394	74683416	14	+	27760321	HL60	viability	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	0.9734247613912663	[71,66]	[144,75]	9	hSpCas9	negative selection	4629355
74683449	74683471	14	-	27760321	HL60	viability	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.32400536216915077	[483,440]	[511,430]	4	hSpCas9	negative selection	4629356
74684446	74684468	14	+	27760321	HL60	viability	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	0.42834917498133596	[347,296]	[282,427]	5	hSpCas9	negative selection	4629357
74684542	74684564	14	-	27760321	HL60	viability	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.17021866476848796	[546,555]	[489,528]	2	hSpCas9	negative selection	4629358
74675892	74675914	14	+	27760321	HT1080	viability	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	0.8280445794305494	[353,275]	[164,285]	4	hSpCas9	negative selection	4712817
74683394	74683416	14	+	27760321	HT1080	viability	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	-1.7132091253584583	[66,51]	[11,1]	-6	hSpCas9	negative selection	4712818
74683449	74683471	14	-	27760321	HT1080	viability	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.5776795739967837	[440,343]	[166,305]	3	hSpCas9	negative selection	4712819
74684446	74684468	14	+	27760321	HT1080	viability	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	0.5809877223456422	[296,231]	[212,96]	3	hSpCas9	negative selection	4712820
74684542	74684564	14	-	27760321	HT1080	viability	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-1.2365589999627364	[555,433]	[55,113]	-5	hSpCas9	negative selection	4712821
74675892	74675914	14	+	27760321	HT29	viability after 7 days	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.5872163291682696	[353,275]	[418,121,287]	-7	hSpCas9	negative selection	4796280
74683394	74683416	14	+	27760321	HT29	viability after 7 days	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	0.29992831334277037	[66,51]	[177,13,101]	4	hSpCas9	negative selection	4796281
74683449	74683471	14	-	27760321	HT29	viability after 7 days	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.15890892702595077	[440,343]	[612,792,298]	2	hSpCas9	negative selection	4796282
74684446	74684468	14	+	27760321	HT29	viability after 7 days	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	0.43854820614957346	[296,231]	[382,560,427]	6	hSpCas9	negative selection	4796283
74684542	74684564	14	-	27760321	HT29	viability after 7 days	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.6733175268648994	[555,433]	[615,256,355]	-7	hSpCas9	negative selection	4796284
74675892	74675914	14	+	27760321	HT29	viability after 25 days	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.14540173491068611	[353,275]	[362,366,233]	-1	hSpCas9	negative selection	4879743
74683394	74683416	14	+	27760321	HT29	viability after 25 days	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	-1.0495993728577142	[66,51]	[23,50,22]	-6	hSpCas9	negative selection	4879744
74683449	74683471	14	-	27760321	HT29	viability after 25 days	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.3429893627732144	[440,343]	[515,703,479]	3	hSpCas9	negative selection	4879745
74684446	74684468	14	+	27760321	HT29	viability after 25 days	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	0.0008346500988395955	[296,231]	[380,252,263]	0	hSpCas9	negative selection	4879746
74684542	74684564	14	-	27760321	HT29	viability after 25 days	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.34744850869828947	[555,433]	[455,280,612]	-3	hSpCas9	negative selection	4879747
74675892	74675914	14	+	27760321	HT29	viability after 22 days	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.10334949274247315	[353,275]	[128,401,492]	-1	hSpCas9	negative selection	4963206
74683394	74683416	14	+	27760321	HT29	viability after 22 days	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	0.21613645332242593	[66,51]	[68,81,88]	2	hSpCas9	negative selection	4963207
74683449	74683471	14	-	27760321	HT29	viability after 22 days	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.5567985460367084	[440,343]	[673,882,442]	6	hSpCas9	negative selection	4963208
74684446	74684468	14	+	27760321	HT29	viability after 22 days	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	-0.10194471693130558	[296,231]	[383,297,168]	-1	hSpCas9	negative selection	4963209
74684542	74684564	14	-	27760321	HT29	viability after 22 days	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.5029461136153838	[555,433]	[388,296,526]	-5	hSpCas9	negative selection	4963210
74675892	74675914	14	+	27760321	HT29	viability after 19 days	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.1357718956918668	[353,275]	[274,270,427]	-1	hSpCas9	negative selection	5046669
74683394	74683416	14	+	27760321	HT29	viability after 19 days	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	-0.5586631302267087	[66,51]	[119,26,0]	-5	hSpCas9	negative selection	5046670
74683449	74683471	14	-	27760321	HT29	viability after 19 days	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.8750169025647794	[440,343]	[998,943,554]	8	hSpCas9	negative selection	5046671
74684446	74684468	14	+	27760321	HT29	viability after 19 days	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	-0.13565020112083537	[296,231]	[409,314,120]	-1	hSpCas9	negative selection	5046672
74684542	74684564	14	-	27760321	HT29	viability after 19 days	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.10708288469937893	[555,433]	[334,692,765]	1	hSpCas9	negative selection	5046673
74675892	74675914	14	+	27760321	HT29	viability after 16 days	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.3972116322689503	[353,275]	[286,326,188]	-4	hSpCas9	negative selection	5130132
74683394	74683416	14	+	27760321	HT29	viability after 16 days	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	0.09569183651468416	[66,51]	[133,80,3]	1	hSpCas9	negative selection	5130133
74683449	74683471	14	-	27760321	HT29	viability after 16 days	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.19084658303844243	[440,343]	[569,580,356]	2	hSpCas9	negative selection	5130134
74684446	74684468	14	+	27760321	HT29	viability after 16 days	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	-0.2556739874479381	[296,231]	[243,179,320]	-3	hSpCas9	negative selection	5130135
74684542	74684564	14	-	27760321	HT29	viability after 16 days	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.659103161292059	[555,433]	[390,269,396]	-6	hSpCas9	negative selection	5130136
74675892	74675914	14	+	27760321	HT29	viability after 13 days	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.1433815879846764	[353,275]	[305,397,290]	-2	hSpCas9	negative selection	5213595
74683394	74683416	14	+	27760321	HT29	viability after 13 days	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	-1.7854233979132963	[66,51]	[13,24,20]	-8	hSpCas9	negative selection	5213596
74683449	74683471	14	-	27760321	HT29	viability after 13 days	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.24321323557086683	[440,343]	[584,703,339]	3	hSpCas9	negative selection	5213597
74684446	74684468	14	+	27760321	HT29	viability after 13 days	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	0.393165310830048	[296,231]	[598,300,313]	5	hSpCas9	negative selection	5213598
74684542	74684564	14	-	27760321	HT29	viability after 13 days	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.5832028661235016	[555,433]	[502,389,263]	-6	hSpCas9	negative selection	5213599
74675892	74675914	14	+	27760321	HT29	viability after 10 days	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.1709817554708988	[353,275]	[360,245,435]	-2	hSpCas9	negative selection	5297058
74683394	74683416	14	+	27760321	HT29	viability after 10 days	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	0.08950179397638225	[66,51]	[12,187,39]	1	hSpCas9	negative selection	5297059
74683449	74683471	14	-	27760321	HT29	viability after 10 days	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.2942543430123243	[440,343]	[589,632,580]	4	hSpCas9	negative selection	5297060
74684446	74684468	14	+	27760321	HT29	viability after 10 days	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	0.20086817801457085	[296,231]	[452,291,390]	2	hSpCas9	negative selection	5297061
74684542	74684564	14	-	27760321	HT29	viability after 10 days	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.5147643696049296	[555,433]	[281,446,565]	-6	hSpCas9	negative selection	5297062
74675892	74675914	14	+	27760321	MOLM13	viability	TAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.3929177253941827	[402,353]	[211,119]	-3	hSpCas9	negative selection	5380521
74683394	74683416	14	+	27760321	MOLM13	viability	ACTTTTACTACGTTGGAATTGG	AREL1	ENSG00000119682	-0.47437646053104254	[71,66]	[51,7]	-3	hSpCas9	negative selection	5380522
74683449	74683471	14	-	27760321	MOLM13	viability	TCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.5730465333940532	[483,440]	[441,341]	4	hSpCas9	negative selection	5380523
74684446	74684468	14	+	27760321	MOLM13	viability	TCCCTTACATGCACTCGGAAGG	AREL1	ENSG00000119682	0.4798406879713959	[347,296]	[468,68]	3	hSpCas9	negative selection	5380524
74684542	74684564	14	-	27760321	MOLM13	viability	CTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.28786339418132506	[546,555]	[288,459]	2	hSpCas9	negative selection	5380525
74712989	74713012	14	+	27661255	K562	viability	GGCAGCACTCAGCAGAAGACGGG	AREL1	ENSG00000119682	-0.833004403640847	[554,493]	[266,208]	-8	dCas9-KRAB	negative selection	5463024
74713015	74713038	14	-	27661255	K562	viability	GGGTCTGTTGGTGGGAGAGTGGG	AREL1	ENSG00000119682	-1.266116338146328	[709,727]	[323,165]	-8	dCas9-KRAB	negative selection	5463025
74713066	74713089	14	-	27661255	K562	viability	GAAAGGGCAATCCCCCGAGCCGG	AREL1	ENSG00000119682	-0.01039096562370212	[1349,1492]	[1215,1047]	0	dCas9-KRAB	negative selection	5463026
74683449	74683472	14	-	27260156	BXPC3	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.08314875520808829	[865]	[870,861,1048,1079]	1	hSpCas9	negative selection	5528804
74675891	74675914	14	+	27260156	BXPC3	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.15147283602221262	[378]	[303,353,330,452]	-4	hSpCas9	negative selection	5528805
74683392	74683415	14	-	27260156	BXPC3	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.4233907002968004	[269]	[348,341,426,402]	8	hSpCas9	negative selection	5528806
74684542	74684565	14	-	27260156	BXPC3	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.2760802574033327	[511]	[381,420,435,546]	-6	hSpCas9	negative selection	5550755
74683449	74683472	14	-	27260156	BXPC3	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.08314875520808829	[865]	[870,861,1048,1079]	1	hSpCas9	negative selection	5550756
74684612	74684635	14	+	27260156	BXPC3	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.16296466883265748	[326]	[265,196,365,415]	-4	hSpCas9	negative selection	5550757
74675698	74675721	14	-	27260156	BXPC3	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.05301372710428853	[268]	[268,201,281,342]	-1	hSpCas9	negative selection	5593088
74683472	74683495	14	+	27260156	BXPC3	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.09658848750600235	[256]	[289,284,259,314]	2	hSpCas9	negative selection	5593089
74675709	74675732	14	+	27260156	BXPC3	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.09318669920341727	[609]	[491,547,659,717]	-2	hSpCas9	negative selection	5593090
74692293	74692316	14	+	27260156	BXPC3	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.2117903876905885	[572]	[508,734,738,821]	4	hSpCas9	negative selection	5615010
74683392	74683415	14	-	27260156	BXPC3	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.4233907002968004	[269]	[348,341,426,402]	8	hSpCas9	negative selection	5615011
74692255	74692278	14	+	27260156	BXPC3	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	-0.11342156488320798	[479]	[413,428,402,633]	-3	hSpCas9	negative selection	5615012
74683449	74683472	14	-	27260156	A673	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.08970855116542387	[865]	[1233,1025,1089,1089]	2	hSpCas9	negative selection	5650055
74675891	74675914	14	+	27260156	A673	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.04529040466115136	[378]	[533,459,416,357]	-1	hSpCas9	negative selection	5650056
74683392	74683415	14	-	27260156	A673	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.07780751535607366	[269]	[375,299,337,359]	1	hSpCas9	negative selection	5650057
74684542	74684565	14	-	27260156	A673	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.42291967539565195	[511]	[531,462,422,421]	-8	hSpCas9	negative selection	5672006
74683449	74683472	14	-	27260156	A673	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.08970855116542387	[865]	[1233,1025,1089,1089]	2	hSpCas9	negative selection	5672007
74684612	74684635	14	+	27260156	A673	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.12302222096981164	[326]	[494,392,364,467]	3	hSpCas9	negative selection	5672008
74675698	74675721	14	-	27260156	A673	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.35208949992699473	[268]	[465,343,317,535]	7	hSpCas9	negative selection	5714339
74683472	74683495	14	+	27260156	A673	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.15461278450811278	[256]	[464,276,382,258]	3	hSpCas9	negative selection	5714340
74675709	74675732	14	+	27260156	A673	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.2544097665373608	[609]	[798,561,526,588]	-6	hSpCas9	negative selection	5714341
74692293	74692316	14	+	27260156	A673	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.0021739461838073404	[572]	[706,561,745,747]	0	hSpCas9	negative selection	5736261
74683392	74683415	14	-	27260156	A673	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.07780751535607366	[269]	[375,299,337,359]	1	hSpCas9	negative selection	5736262
74692255	74692278	14	+	27260156	A673	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	-0.07700194145050604	[479]	[540,546,429,673]	-2	hSpCas9	negative selection	5736263
74683449	74683472	14	-	27260156	A375	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.10519713528530705	[865]	[688,1169,1351,1138]	1	hSpCas9	negative selection	5771306
74675891	74675914	14	+	27260156	A375	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.40876228648343604	[378]	[392,347,260,332]	-5	hSpCas9	negative selection	5771307
74683392	74683415	14	-	27260156	A375	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.21494741598716793	[269]	[304,341,446,364]	3	hSpCas9	negative selection	5771308
74684542	74684565	14	-	27260156	A375	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.30663448423698886	[511]	[338,641,505,467]	-4	hSpCas9	negative selection	5793257
74683449	74683472	14	-	27260156	A375	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.10519713528530705	[865]	[688,1169,1351,1138]	1	hSpCas9	negative selection	5793258
74684612	74684635	14	+	27260156	A375	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.3496899821132736	[326]	[466,553,574,371]	5	hSpCas9	negative selection	5793259
74675698	74675721	14	-	27260156	A375	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.09979698047762897	[268]	[224,308,508,301]	1	hSpCas9	negative selection	5835590
74683472	74683495	14	+	27260156	A375	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.0012765553428499832	[256]	[275,310,332,281]	0	hSpCas9	negative selection	5835591
74675709	74675732	14	+	27260156	A375	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.3560347121424106	[609]	[913,840,863,1003]	5	hSpCas9	negative selection	5835592
74692293	74692316	14	+	27260156	A375	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.19541756476549843	[572]	[446,806,678,448]	-3	hSpCas9	negative selection	5857512
74683392	74683415	14	-	27260156	A375	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.21494741598716793	[269]	[304,341,446,364]	3	hSpCas9	negative selection	5857513
74692255	74692278	14	+	27260156	A375	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.27769881971438826	[479]	[438,830,746,713]	4	hSpCas9	negative selection	5857514
74683449	74683472	14	-	27260156	COLO741	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.00923897523853634	[865]	[1077,1101,1112]	0	hSpCas9	negative selection	5892557
74675891	74675914	14	+	27260156	COLO741	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.09913830523301959	[378]	[418,501,432]	-2	hSpCas9	negative selection	5892558
74683392	74683415	14	-	27260156	COLO741	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.28646623860745846	[269]	[436,325,493]	6	hSpCas9	negative selection	5892559
74684542	74684565	14	-	27260156	COLO741	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.17670853250420324	[511]	[587,599,549]	-4	hSpCas9	negative selection	5914508
74683449	74683472	14	-	27260156	COLO741	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.00923897523853634	[865]	[1077,1101,1112]	0	hSpCas9	negative selection	5914509
74684612	74684635	14	+	27260156	COLO741	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.4266528398672671	[326]	[639,641,418]	8	hSpCas9	negative selection	5914510
74675698	74675721	14	-	27260156	COLO741	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.054258977110821394	[268]	[340,374,280]	-1	hSpCas9	negative selection	5956841
74683472	74683495	14	+	27260156	COLO741	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.1801106072517875	[256]	[293,319,485]	4	hSpCas9	negative selection	5956842
74675709	74675732	14	+	27260156	COLO741	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.002362060998023996	[609]	[868,842,645]	0	hSpCas9	negative selection	5956843
74692293	74692316	14	+	27260156	COLO741	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.15042679728591224	[572]	[750,713,529]	-3	hSpCas9	negative selection	5978763
74683392	74683415	14	-	27260156	COLO741	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.28646623860745846	[269]	[436,325,493]	6	hSpCas9	negative selection	5978764
74692255	74692278	14	+	27260156	COLO741	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.1543378284420965	[479]	[656,606,772]	3	hSpCas9	negative selection	5978765
74683449	74683472	14	-	27260156	CAL120	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.07139739111613086	[865]	[1141,1071,1182]	1	hSpCas9	negative selection	6013808
74675891	74675914	14	+	27260156	CAL120	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.0020368420348227945	[378]	[621,319,492]	0	hSpCas9	negative selection	6013809
74683392	74683415	14	-	27260156	CAL120	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.2854956041540342	[269]	[364,293,182]	-4	hSpCas9	negative selection	6013810
74684542	74684565	14	-	27260156	CAL120	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.22464214741743915	[511]	[638,484,525]	-3	hSpCas9	negative selection	6035759
74683449	74683472	14	-	27260156	CAL120	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.07139739111613086	[865]	[1141,1071,1182]	1	hSpCas9	negative selection	6035760
74684612	74684635	14	+	27260156	CAL120	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.2874174651966023	[326]	[516,326,645]	4	hSpCas9	negative selection	6035761
74675698	74675721	14	-	27260156	CAL120	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.6031008588913844	[268]	[864,438,278]	8	hSpCas9	negative selection	6078092
74683472	74683495	14	+	27260156	CAL120	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.026322855262974842	[256]	[331,429,184]	0	hSpCas9	negative selection	6078093
74675709	74675732	14	+	27260156	CAL120	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.05731886193787272	[609]	[1168,559,528]	-1	hSpCas9	negative selection	6078094
74692293	74692316	14	+	27260156	CAL120	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.2939301741858432	[572]	[952,639,1037]	4	hSpCas9	negative selection	6100014
74683392	74683415	14	-	27260156	CAL120	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.2854956041540342	[269]	[364,293,182]	-4	hSpCas9	negative selection	6100015
74692255	74692278	14	+	27260156	CAL120	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	-0.14254120643566168	[479]	[434,510,658]	-2	hSpCas9	negative selection	6100016
74683449	74683472	14	-	27260156	CADOES1	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.11897979967929284	[865]	[893,780,933,889]	2	hSpCas9	negative selection	6135059
74675891	74675914	14	+	27260156	CADOES1	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.2104957825505155	[378]	[256,329,268,364]	-4	hSpCas9	negative selection	6135060
74683392	74683415	14	-	27260156	CADOES1	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3638654794755751	[269]	[329,253,319,390]	6	hSpCas9	negative selection	6135061
74684542	74684565	14	-	27260156	CADOES1	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.45340644323172363	[511]	[321,307,337,425]	-7	hSpCas9	negative selection	6157010
74683449	74683472	14	-	27260156	CADOES1	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.11897979967929284	[865]	[893,780,933,889]	2	hSpCas9	negative selection	6157011
74684612	74684635	14	+	27260156	CADOES1	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.14780455199006393	[326]	[250,217,302,327]	-3	hSpCas9	negative selection	6157012
74675698	74675721	14	-	27260156	CADOES1	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.13977995021004253	[268]	[205,128,349,222]	-2	hSpCas9	negative selection	6199343
74683472	74683495	14	+	27260156	CADOES1	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.14590870400058575	[256]	[208,343,193,312]	2	hSpCas9	negative selection	6199344
74675709	74675732	14	+	27260156	CADOES1	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.12114832018340532	[609]	[688,433,715,628]	2	hSpCas9	negative selection	6199345
74692293	74692316	14	+	27260156	CADOES1	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.1847478840305442	[572]	[528,731,642,515]	3	hSpCas9	negative selection	6221265
74683392	74683415	14	-	27260156	CADOES1	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3638654794755751	[269]	[329,253,319,390]	6	hSpCas9	negative selection	6221266
74692255	74692278	14	+	27260156	CADOES1	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.26740207797733134	[479]	[549,493,598,504]	4	hSpCas9	negative selection	6221267
74683449	74683472	14	-	27260156	EWS502	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.0919262119460057	[865]	[784,1015,1068,1065]	1	hSpCas9	negative selection	6256310
74675891	74675914	14	+	27260156	EWS502	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.3071347386739357	[378]	[296,292,323,391]	-5	hSpCas9	negative selection	6256311
74683392	74683415	14	-	27260156	EWS502	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.31100446530343456	[269]	[320,411,317,368]	5	hSpCas9	negative selection	6256312
74684542	74684565	14	-	27260156	EWS502	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.16540782432510093	[511]	[650,366,362,537]	-3	hSpCas9	negative selection	6278261
74683449	74683472	14	-	27260156	EWS502	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.0919262119460057	[865]	[784,1015,1068,1065]	1	hSpCas9	negative selection	6278262
74684612	74684635	14	+	27260156	EWS502	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.07015465823685496	[326]	[220,309,286,527]	-1	hSpCas9	negative selection	6278263
74675698	74675721	14	-	27260156	EWS502	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.19665674559247126	[268]	[285,271,322,438]	3	hSpCas9	negative selection	6320594
74683472	74683495	14	+	27260156	EWS502	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.2624361937514115	[256]	[233,185,373,543]	4	hSpCas9	negative selection	6320595
74675709	74675732	14	+	27260156	EWS502	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.08071964813478866	[609]	[696,511,765,767]	1	hSpCas9	negative selection	6320596
74692293	74692316	14	+	27260156	EWS502	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.07104169983749803	[572]	[454,525,679,672]	-1	hSpCas9	negative selection	6342516
74683392	74683415	14	-	27260156	EWS502	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.31100446530343456	[269]	[320,411,317,368]	5	hSpCas9	negative selection	6342517
74692255	74692278	14	+	27260156	EWS502	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.041642322825048886	[479]	[517,536,497,538]	0	hSpCas9	negative selection	6342518
74683449	74683472	14	-	27260156	EW8	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.05560594694432697	[865]	[648,692,783,770]	1	hSpCas9	negative selection	6377561
74675891	74675914	14	+	27260156	EW8	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.0397157960212699	[378]	[388,297,175,361]	0	hSpCas9	negative selection	6377562
74683392	74683415	14	-	27260156	EW8	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.015139793344912111	[269]	[210,223,191,241]	0	hSpCas9	negative selection	6377563
74684542	74684565	14	-	27260156	EW8	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.42378471459794453	[511]	[343,394,212,304]	-7	hSpCas9	negative selection	6399512
74683449	74683472	14	-	27260156	EW8	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.05560594694432697	[865]	[648,692,783,770]	1	hSpCas9	negative selection	6399513
74684612	74684635	14	+	27260156	EW8	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.3337793120852677	[326]	[183,225,195,233]	-6	hSpCas9	negative selection	6399514
74675698	74675721	14	-	27260156	EW8	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.32636250148689777	[268]	[273,247,263,307]	6	hSpCas9	negative selection	6441845
74683472	74683495	14	+	27260156	EW8	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.006904690555741166	[256]	[199,282,142,212]	0	hSpCas9	negative selection	6441846
74675709	74675732	14	+	27260156	EW8	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.18607833686718078	[609]	[462,391,414,472]	-4	hSpCas9	negative selection	6441847
74692293	74692316	14	+	27260156	EW8	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.15929605387576798	[572]	[511,362,340,468]	-3	hSpCas9	negative selection	6463767
74683392	74683415	14	-	27260156	EW8	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.015139793344912111	[269]	[210,223,191,241]	0	hSpCas9	negative selection	6463768
74692255	74692278	14	+	27260156	EW8	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.24163506569350973	[479]	[749,360,377,394]	4	hSpCas9	negative selection	6463769
74683449	74683472	14	-	27260156	CORL105	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.04238117205161995	[865]	[1087,984,1197,931]	0	hSpCas9	negative selection	6498812
74675891	74675914	14	+	27260156	CORL105	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.2017546507722232	[378]	[390,454,284,394]	-4	hSpCas9	negative selection	6498813
74683392	74683415	14	-	27260156	CORL105	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.27424370899080275	[269]	[536,263,327,398]	5	hSpCas9	negative selection	6498814
74684542	74684565	14	-	27260156	CORL105	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.19389957190859597	[511]	[460,628,568,439]	-4	hSpCas9	negative selection	6520763
74683449	74683472	14	-	27260156	CORL105	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.04238117205161995	[865]	[1087,984,1197,931]	0	hSpCas9	negative selection	6520764
74684612	74684635	14	+	27260156	CORL105	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.08581124040210397	[326]	[307,432,350,345]	-1	hSpCas9	negative selection	6520765
74675698	74675721	14	-	27260156	CORL105	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.39517388615714655	[268]	[430,393,467,372]	7	hSpCas9	negative selection	6563096
74683472	74683495	14	+	27260156	CORL105	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.047850114044646896	[256]	[198,359,387,227]	-1	hSpCas9	negative selection	6563097
74675709	74675732	14	+	27260156	CORL105	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.12324054648759925	[609]	[672,618,801,552]	-2	hSpCas9	negative selection	6563098
74692293	74692316	14	+	27260156	CORL105	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.1447090064647478	[572]	[712,429,695,608]	-3	hSpCas9	negative selection	6585018
74683392	74683415	14	-	27260156	CORL105	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.27424370899080275	[269]	[536,263,327,398]	5	hSpCas9	negative selection	6585019
74692255	74692278	14	+	27260156	CORL105	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	-0.181341421598693	[479]	[530,463,464,518]	-3	hSpCas9	negative selection	6585020
74683449	74683472	14	-	27260156	HS294T	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.26251867944317075	[865]	[283,483,383,473]	3	hSpCas9	negative selection	6620063
74675891	74675914	14	+	27260156	HS294T	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.18322009006549922	[378]	[160,66,131,159]	-3	hSpCas9	negative selection	6620064
74683392	74683415	14	-	27260156	HS294T	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.6284530433994135	[269]	[167,106,155,225]	7	hSpCas9	negative selection	6620065
74684542	74684565	14	-	27260156	HS294T	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.6592940586284998	[511]	[102,132,130,137]	-7	hSpCas9	negative selection	6642014
74683449	74683472	14	-	27260156	HS294T	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.26251867944317075	[865]	[283,483,383,473]	3	hSpCas9	negative selection	6642015
74684612	74684635	14	+	27260156	HS294T	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.29691041537566487	[326]	[79,133,97,99]	-4	hSpCas9	negative selection	6642016
74675698	74675721	14	-	27260156	HS294T	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.3465253905314556	[268]	[59,64,80,131]	-5	hSpCas9	negative selection	6684347
74683472	74683495	14	+	27260156	HS294T	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.37493897978739665	[256]	[74,70,76,84]	-5	hSpCas9	negative selection	6684348
74675709	74675732	14	+	27260156	HS294T	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.040085808240308274	[609]	[253,185,195,289]	0	hSpCas9	negative selection	6684349
74692293	74692316	14	+	27260156	HS294T	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.14804406221529226	[572]	[195,136,261,207]	-2	hSpCas9	negative selection	6706269
74683392	74683415	14	-	27260156	HS294T	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.6284530433994135	[269]	[167,106,155,225]	7	hSpCas9	negative selection	6706270
74692255	74692278	14	+	27260156	HS294T	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.16848031896494597	[479]	[136,179,228,312]	2	hSpCas9	negative selection	6706271
74683449	74683472	14	-	27260156	HCC44	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.06541289727628008	[865]	[1045,728,1545,907]	1	hSpCas9	negative selection	6741314
74675891	74675914	14	+	27260156	HCC44	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.4330792161900864	[378]	[180,373,392,311]	-6	hSpCas9	negative selection	6741315
74683392	74683415	14	-	27260156	HCC44	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.2553559073539883	[269]	[249,333,607,300]	4	hSpCas9	negative selection	6741316
74684542	74684565	14	-	27260156	HCC44	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.1792641679907871	[511]	[490,372,532,660]	-3	hSpCas9	negative selection	6763265
74683449	74683472	14	-	27260156	HCC44	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.06541289727628008	[865]	[1045,728,1545,907]	1	hSpCas9	negative selection	6763266
74684612	74684635	14	+	27260156	HCC44	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.3296566169276739	[326]	[641,408,370,441]	5	hSpCas9	negative selection	6763267
74675698	74675721	14	-	27260156	HCC44	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.30952256738467976	[268]	[214,143,475,197]	-5	hSpCas9	negative selection	6805598
74683472	74683495	14	+	27260156	HCC44	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.5810475275891421	[256]	[438,38,170,167]	-7	hSpCas9	negative selection	6805599
74675709	74675732	14	+	27260156	HCC44	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.05928122771360894	[609]	[938,734,635,567]	0	hSpCas9	negative selection	6805600
74692293	74692316	14	+	27260156	HCC44	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.531480774223198	[572]	[460,435,439,453]	-7	hSpCas9	negative selection	6827520
74683392	74683415	14	-	27260156	HCC44	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.2553559073539883	[269]	[249,333,607,300]	4	hSpCas9	negative selection	6827521
74692255	74692278	14	+	27260156	HCC44	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	-0.06176586180806555	[479]	[734,416,483,469]	-1	hSpCas9	negative selection	6827522
74683449	74683472	14	-	27260156	G402	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.3688931926055995	[865]	[1034,1160,1269,1900]	4	hSpCas9	negative selection	6862565
74675891	74675914	14	+	27260156	G402	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.433465783220211	[378]	[242,439,466,215]	-5	hSpCas9	negative selection	6862566
74683392	74683415	14	-	27260156	G402	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.6251986277075399	[269]	[259,328,149,131]	-6	hSpCas9	negative selection	6862567
74684542	74684565	14	-	27260156	G402	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.26454342458310814	[511]	[530,524,712,320]	-3	hSpCas9	negative selection	6884516
74683449	74683472	14	-	27260156	G402	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.3688931926055995	[865]	[1034,1160,1269,1900]	4	hSpCas9	negative selection	6884517
74684612	74684635	14	+	27260156	G402	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.2971402459963143	[326]	[395,430,243,246]	-4	hSpCas9	negative selection	6884518
74675698	74675721	14	-	27260156	G402	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.8350955743963413	[268]	[707,594,528,528]	9	hSpCas9	negative selection	6926849
74683472	74683495	14	+	27260156	G402	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.0385631396626841	[256]	[355,231,368,267]	0	hSpCas9	negative selection	6926850
74675709	74675732	14	+	27260156	G402	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.2192901443206589	[609]	[1289,1019,636,598]	2	hSpCas9	negative selection	6926851
74692293	74692316	14	+	27260156	G402	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.2766584984197181	[572]	[627,574,328,771]	-3	hSpCas9	negative selection	6948771
74683392	74683415	14	-	27260156	G402	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.6251986277075399	[269]	[259,328,149,131]	-6	hSpCas9	negative selection	6948772
74692255	74692278	14	+	27260156	G402	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	-0.08856100956622419	[479]	[629,579,510,495]	-1	hSpCas9	negative selection	6948773
74683449	74683472	14	-	27260156	L33	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.19441871100373842	[865]	[1250,347,583,927]	4	hSpCas9	negative selection	6983816
74675891	74675914	14	+	27260156	L33	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	0.4433163599107708	[378]	[488,221,347,477]	8	hSpCas9	negative selection	6983817
74683392	74683415	14	-	27260156	L33	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3120451159096581	[269]	[320,136,245,294]	6	hSpCas9	negative selection	6983818
74684542	74684565	14	-	27260156	L33	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.3338917502134067	[511]	[470,152,260,363]	-7	hSpCas9	negative selection	7005767
74683449	74683472	14	-	27260156	L33	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.19441871100373842	[865]	[1250,347,583,927]	4	hSpCas9	negative selection	7005768
74684612	74684635	14	+	27260156	L33	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.1105458856580766	[326]	[327,137,248,351]	2	hSpCas9	negative selection	7005769
74675698	74675721	14	-	27260156	L33	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.40097383246773405	[268]	[363,117,268,340]	8	hSpCas9	negative selection	7048100
74683472	74683495	14	+	27260156	L33	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.18795325609127955	[256]	[274,156,157,261]	4	hSpCas9	negative selection	7048101
74675709	74675732	14	+	27260156	L33	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.29803711689956325	[609]	[539,182,324,479]	-6	hSpCas9	negative selection	7048102
74692293	74692316	14	+	27260156	L33	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.05843171771243999	[572]	[741,255,313,516]	1	hSpCas9	negative selection	7070022
74683392	74683415	14	-	27260156	L33	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3120451159096581	[269]	[320,136,245,294]	6	hSpCas9	negative selection	7070023
74692255	74692278	14	+	27260156	L33	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	-0.10546082883758294	[479]	[512,177,280,388]	-2	hSpCas9	negative selection	7070024
74683449	74683472	14	-	27260156	K562	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.5926998904577138	[865]	[1132,1074,1583,866]	7	hSpCas9	negative selection	7105067
74675891	74675914	14	+	27260156	K562	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	0.2125583356160049	[378]	[237,209,778,316]	2	hSpCas9	negative selection	7105068
74683392	74683415	14	-	27260156	K562	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.672089835157994	[269]	[667,139,315,408]	8	hSpCas9	negative selection	7105069
74684542	74684565	14	-	27260156	K562	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.22635110764178762	[511]	[433,603,514,562]	3	hSpCas9	negative selection	7127018
74683449	74683472	14	-	27260156	K562	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.5926998904577138	[865]	[1132,1074,1583,866]	7	hSpCas9	negative selection	7127019
74684612	74684635	14	+	27260156	K562	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.09561756774256364	[326]	[135,260,409,403]	1	hSpCas9	negative selection	7127020
74675698	74675721	14	-	27260156	K562	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.24899058825556808	[268]	[630,166,103,256]	3	hSpCas9	negative selection	7169351
74683472	74683495	14	+	27260156	K562	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.34849178277505233	[256]	[223,252,178,474]	4	hSpCas9	negative selection	7169352
74675709	74675732	14	+	27260156	K562	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.039414789903742864	[609]	[656,367,627,566]	0	hSpCas9	negative selection	7169353
74692293	74692316	14	+	27260156	K562	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.27340921174550215	[572]	[928,433,182,892]	3	hSpCas9	negative selection	7191273
74683392	74683415	14	-	27260156	K562	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.672089835157994	[269]	[667,139,315,408]	8	hSpCas9	negative selection	7191274
74692255	74692278	14	+	27260156	K562	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.3052447312557109	[479]	[830,435,298,553]	4	hSpCas9	negative selection	7191275
74683449	74683472	14	-	27260156	HT29	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.05584350989547815	[865]	[1162,1246,1210,802]	1	hSpCas9	negative selection	7226318
74675891	74675914	14	+	27260156	HT29	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.40035360841605616	[378]	[315,404,316,356]	-6	hSpCas9	negative selection	7226319
74683392	74683415	14	-	27260156	HT29	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.31653662514526243	[269]	[674,388,314,286]	6	hSpCas9	negative selection	7226320
74684542	74684565	14	-	27260156	HT29	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.17445299097411232	[511]	[432,642,467,644]	-4	hSpCas9	negative selection	7248269
74683449	74683472	14	-	27260156	HT29	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.05584350989547815	[865]	[1162,1246,1210,802]	1	hSpCas9	negative selection	7248270
74684612	74684635	14	+	27260156	HT29	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.1147290431233049	[326]	[356,364,471,503]	2	hSpCas9	negative selection	7248271
74675698	74675721	14	-	27260156	HT29	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.1578974758261119	[268]	[600,360,367,168]	3	hSpCas9	negative selection	7290602
74683472	74683495	14	+	27260156	HT29	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.06136978629307632	[256]	[270,231,371,310]	-1	hSpCas9	negative selection	7290603
74675709	74675732	14	+	27260156	HT29	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.023404578782489804	[609]	[752,767,791,618]	0	hSpCas9	negative selection	7290604
74692293	74692316	14	+	27260156	HT29	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.0068756110434196605	[572]	[812,719,800,472]	0	hSpCas9	negative selection	7312524
74683392	74683415	14	-	27260156	HT29	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.31653662514526243	[269]	[674,388,314,286]	6	hSpCas9	negative selection	7312525
74692255	74692278	14	+	27260156	HT29	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.0005350078701249483	[479]	[719,518,615,491]	0	hSpCas9	negative selection	7312526
74683449	74683472	14	-	27260156	MHHES1	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.09233452462736458	[865]	[837,1192,998,1084]	1	hSpCas9	negative selection	7347569
74675891	74675914	14	+	27260156	MHHES1	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.29049475912160516	[378]	[266,423,352,342]	-5	hSpCas9	negative selection	7347570
74683392	74683415	14	-	27260156	MHHES1	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3833205410989674	[269]	[278,521,394,382]	7	hSpCas9	negative selection	7347571
74684542	74684565	14	-	27260156	MHHES1	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.6560113044383791	[511]	[375,236,393,422]	-8	hSpCas9	negative selection	7369520
74683449	74683472	14	-	27260156	MHHES1	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.09233452462736458	[865]	[837,1192,998,1084]	1	hSpCas9	negative selection	7369521
74684612	74684635	14	+	27260156	MHHES1	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.14572233823401226	[326]	[451,392,229,280]	-3	hSpCas9	negative selection	7369522
74675698	74675721	14	-	27260156	MHHES1	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.040680518101526064	[268]	[232,345,451,168]	0	hSpCas9	negative selection	7411853
74683472	74683495	14	+	27260156	MHHES1	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.410725744113448	[256]	[315,451,554,240]	7	hSpCas9	negative selection	7411854
74675709	74675732	14	+	27260156	MHHES1	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.199310854106805	[609]	[747,905,810,699]	3	hSpCas9	negative selection	7411855
74692293	74692316	14	+	27260156	MHHES1	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.159042937592407	[572]	[765,470,667,438]	-3	hSpCas9	negative selection	7433775
74683392	74683415	14	-	27260156	MHHES1	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3833205410989674	[269]	[278,521,394,382]	7	hSpCas9	negative selection	7433776
74692255	74692278	14	+	27260156	MHHES1	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.09046633257654842	[479]	[660,491,578,561]	1	hSpCas9	negative selection	7433777
74683449	74683472	14	-	27260156	MEWO	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.23244693581378983	[865]	[1107,861,915]	5	hSpCas9	negative selection	7468820
74675891	74675914	14	+	27260156	MEWO	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.11307295675611712	[378]	[432,295,274]	-2	hSpCas9	negative selection	7468821
74683392	74683415	14	-	27260156	MEWO	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.40270916103586324	[269]	[344,308,349]	8	hSpCas9	negative selection	7468822
74684542	74684565	14	-	27260156	MEWO	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.23735731053958073	[511]	[384,364,464]	-5	hSpCas9	negative selection	7490771
74683449	74683472	14	-	27260156	MEWO	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.23244693581378983	[865]	[1107,861,915]	5	hSpCas9	negative selection	7490772
74684612	74684635	14	+	27260156	MEWO	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.250430034061163	[326]	[486,266,361]	5	hSpCas9	negative selection	7490773
74675698	74675721	14	-	27260156	MEWO	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.10085412462267385	[268]	[250,258,295]	2	hSpCas9	negative selection	7533104
74683472	74683495	14	+	27260156	MEWO	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.11243021189849667	[256]	[281,167,228]	-2	hSpCas9	negative selection	7533105
74675709	74675732	14	+	27260156	MEWO	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.14505746564997837	[609]	[717,373,495]	-3	hSpCas9	negative selection	7533106
74692293	74692316	14	+	27260156	MEWO	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.04991116351972294	[572]	[689,472,423]	-1	hSpCas9	negative selection	7555026
74683392	74683415	14	-	27260156	MEWO	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.40270916103586324	[269]	[344,308,349]	8	hSpCas9	negative selection	7555027
74692255	74692278	14	+	27260156	MEWO	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.01002122547184978	[479]	[689,363,348]	0	hSpCas9	negative selection	7555028
74683449	74683472	14	-	27260156	LNCAPCLONEFGC	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.024268809943888248	[865]	[638,786,861,811]	0	hSpCas9	negative selection	7590071
74675891	74675914	14	+	27260156	LNCAPCLONEFGC	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.39517931223458413	[378]	[227,214,282,324]	-6	hSpCas9	negative selection	7590072
74683392	74683415	14	-	27260156	LNCAPCLONEFGC	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.12163708013175345	[269]	[331,176,327,240]	1	hSpCas9	negative selection	7590073
74684542	74684565	14	-	27260156	LNCAPCLONEFGC	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.5102877390610036	[511]	[318,299,297,382]	-7	hSpCas9	negative selection	7612022
74683449	74683472	14	-	27260156	LNCAPCLONEFGC	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.024268809943888248	[865]	[638,786,861,811]	0	hSpCas9	negative selection	7612023
74684612	74684635	14	+	27260156	LNCAPCLONEFGC	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.29320488311849424	[326]	[434,262,390,371]	4	hSpCas9	negative selection	7612024
74675698	74675721	14	-	27260156	LNCAPCLONEFGC	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.34612653448981356	[268]	[275,311,381,279]	5	hSpCas9	negative selection	7654355
74683472	74683495	14	+	27260156	LNCAPCLONEFGC	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.002143455655754467	[256]	[157,249,353,185]	0	hSpCas9	negative selection	7654356
74675709	74675732	14	+	27260156	LNCAPCLONEFGC	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.2261840169556028	[609]	[609,782,661,523]	3	hSpCas9	negative selection	7654357
74692293	74692316	14	+	27260156	LNCAPCLONEFGC	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.0017451298299798745	[572]	[580,465,574,461]	0	hSpCas9	negative selection	7676277
74683392	74683415	14	-	27260156	LNCAPCLONEFGC	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.12163708013175345	[269]	[331,176,327,240]	1	hSpCas9	negative selection	7676278
74692255	74692278	14	+	27260156	LNCAPCLONEFGC	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.48092223287726754	[479]	[794,376,852,449]	7	hSpCas9	negative selection	7676279
74683449	74683472	14	-	27260156	PANC0327	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.20692979885549134	[865]	[790,739,1146,884]	3	hSpCas9	negative selection	7711322
74675891	74675914	14	+	27260156	PANC0327	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.3757723217561081	[378]	[198,289,309,229]	-5	hSpCas9	negative selection	7711323
74683392	74683415	14	-	27260156	PANC0327	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.19253078144870017	[269]	[214,232,247,140]	-3	hSpCas9	negative selection	7711324
74684542	74684565	14	-	27260156	PANC0327	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.17997905084153615	[511]	[242,430,450,463]	-3	hSpCas9	negative selection	7733273
74683449	74683472	14	-	27260156	PANC0327	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.20692979885549134	[865]	[790,739,1146,884]	3	hSpCas9	negative selection	7733274
74684612	74684635	14	+	27260156	PANC0327	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.005708508605333562	[326]	[365,277,156,372]	0	hSpCas9	negative selection	7733275
74675698	74675721	14	-	27260156	PANC0327	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.10886430787734058	[268]	[183,237,191,266]	-2	hSpCas9	negative selection	7775606
74683472	74683495	14	+	27260156	PANC0327	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.8801244418839816	[256]	[196,61,80,169]	-8	hSpCas9	negative selection	7775607
74675709	74675732	14	+	27260156	PANC0327	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.055419145829774974	[609]	[625,381,450,652]	-1	hSpCas9	negative selection	7775608
74692293	74692316	14	+	27260156	PANC0327	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.29667768257799576	[572]	[480,459,1069,499]	4	hSpCas9	negative selection	7797528
74683392	74683415	14	-	27260156	PANC0327	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.19253078144870017	[269]	[214,232,247,140]	-3	hSpCas9	negative selection	7797529
74692255	74692278	14	+	27260156	PANC0327	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.12005657398700115	[479]	[658,464,307,436]	1	hSpCas9	negative selection	7797530
74683449	74683472	14	-	27260156	NCIH2009	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.008698492178173978	[865]	[1432,1180,1078]	0	hSpCas9	negative selection	7832573
74675891	74675914	14	+	27260156	NCIH2009	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	0.3136113571093398	[378]	[693,562,724]	4	hSpCas9	negative selection	7832574
74683392	74683415	14	-	27260156	NCIH2009	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.5756331550796538	[269]	[494,361,818]	7	hSpCas9	negative selection	7832575
74684542	74684565	14	-	27260156	NCIH2009	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.7452452414343224	[511]	[537,344,419]	-7	hSpCas9	negative selection	7854524
74683449	74683472	14	-	27260156	NCIH2009	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.008698492178173978	[865]	[1432,1180,1078]	0	hSpCas9	negative selection	7854525
74684612	74684635	14	+	27260156	NCIH2009	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.09625968596042805	[326]	[561,537,377]	1	hSpCas9	negative selection	7854526
74675698	74675721	14	-	27260156	NCIH2009	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.06597805390235656	[268]	[560,322,329]	0	hSpCas9	negative selection	7896857
74683472	74683495	14	+	27260156	NCIH2009	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.015010041514184058	[256]	[453,245,407]	0	hSpCas9	negative selection	7896858
74675709	74675732	14	+	27260156	NCIH2009	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.19084392302169256	[609]	[842,812,1237]	2	hSpCas9	negative selection	7896859
74692293	74692316	14	+	27260156	NCIH2009	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.28050711969197917	[572]	[717,595,674]	-4	hSpCas9	negative selection	7918779
74683392	74683415	14	-	27260156	NCIH2009	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.5756331550796538	[269]	[494,361,818]	7	hSpCas9	negative selection	7918780
74692255	74692278	14	+	27260156	NCIH2009	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.35209897772261406	[479]	[818,649,1093]	5	hSpCas9	negative selection	7918781
74683449	74683472	14	-	27260156	NCIH1373	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.10275155196385422	[865]	[1331,1017,1078,200]	1	hSpCas9	negative selection	7953824
74675891	74675914	14	+	27260156	NCIH1373	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.34934387604811823	[378]	[201,256,430,113]	-3	hSpCas9	negative selection	7953825
74683392	74683415	14	-	27260156	NCIH1373	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.00822257519334546	[269]	[287,275,311,89]	0	hSpCas9	negative selection	7953826
74684542	74684565	14	-	27260156	NCIH1373	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-1.1897279919808386	[511]	[289,227,177,84]	-8	hSpCas9	negative selection	7975775
74683449	74683472	14	-	27260156	NCIH1373	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.10275155196385422	[865]	[1331,1017,1078,200]	1	hSpCas9	negative selection	7975776
74684612	74684635	14	+	27260156	NCIH1373	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.054373968435465714	[326]	[423,378,214,136]	0	hSpCas9	negative selection	7975777
74675698	74675721	14	-	27260156	NCIH1373	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.04382645515043648	[268]	[154,154,402,139]	0	hSpCas9	negative selection	8018108
74683472	74683495	14	+	27260156	NCIH1373	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.1917168221641966	[256]	[239,460,314,69]	2	hSpCas9	negative selection	8018109
74675709	74675732	14	+	27260156	NCIH1373	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.4430579357523952	[609]	[1246,739,770,271]	4	hSpCas9	negative selection	8018110
74692293	74692316	14	+	27260156	NCIH1373	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.2370628605272801	[572]	[866,417,578,95]	-2	hSpCas9	negative selection	8040030
74683392	74683415	14	-	27260156	NCIH1373	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.00822257519334546	[269]	[287,275,311,89]	0	hSpCas9	negative selection	8040031
74692255	74692278	14	+	27260156	NCIH1373	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	1.3942455951800163	[479]	[688,2772,888,268]	9	hSpCas9	negative selection	8040032
74683449	74683472	14	-	27260156	PATU8902	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.10306345633381464	[865]	[1150,906,1228,1172]	-1	hSpCas9	negative selection	8075075
74675891	74675914	14	+	27260156	PATU8902	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-1.0768305940643033	[378]	[209,240,256,294]	-7	hSpCas9	negative selection	8075076
74683392	74683415	14	-	27260156	PATU8902	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.6012893204942046	[269]	[515,552,542,686]	6	hSpCas9	negative selection	8075077
74684542	74684565	14	-	27260156	PATU8902	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.48960894001370214	[511]	[356,843,289,607]	-5	hSpCas9	negative selection	8097026
74683449	74683472	14	-	27260156	PATU8902	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.10306345633381464	[865]	[1150,906,1228,1172]	-1	hSpCas9	negative selection	8097027
74684612	74684635	14	+	27260156	PATU8902	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.3621779272521375	[326]	[665,567,469,671]	4	hSpCas9	negative selection	8097028
74675698	74675721	14	-	27260156	PATU8902	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.226295804061874	[268]	[243,458,492,555]	2	hSpCas9	negative selection	8139359
74683472	74683495	14	+	27260156	PATU8902	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.47486872223975973	[256]	[445,106,227,250]	-5	hSpCas9	negative selection	8139360
74675709	74675732	14	+	27260156	PATU8902	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.03766696251902624	[609]	[1297,897,517,850]	0	hSpCas9	negative selection	8139361
74692293	74692316	14	+	27260156	PATU8902	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.13023704526929542	[572]	[632,987,573,761]	-1	hSpCas9	negative selection	8161281
74683392	74683415	14	-	27260156	PATU8902	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.6012893204942046	[269]	[515,552,542,686]	6	hSpCas9	negative selection	8161282
74692255	74692278	14	+	27260156	PATU8902	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.26371840234956756	[479]	[589,310,825,1562]	2	hSpCas9	negative selection	8161283
74683449	74683472	14	-	27260156	PANC1	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.12340677515093257	[865]	[608,775,609,735]	-2	hSpCas9	negative selection	8196326
74675891	74675914	14	+	27260156	PANC1	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.2586858404274096	[378]	[334,452,197,152]	-4	hSpCas9	negative selection	8196327
74683392	74683415	14	-	27260156	PANC1	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3426396037994839	[269]	[292,270,435,185]	5	hSpCas9	negative selection	8196328
74684542	74684565	14	-	27260156	PANC1	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.1500868776952291	[511]	[491,477,358,282]	-2	hSpCas9	negative selection	8218277
74683449	74683472	14	-	27260156	PANC1	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.12340677515093257	[865]	[608,775,609,735]	-2	hSpCas9	negative selection	8218278
74684612	74684635	14	+	27260156	PANC1	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.02330532141533692	[326]	[230,461,289,204]	0	hSpCas9	negative selection	8218279
74675698	74675721	14	-	27260156	PANC1	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.3832392583483109	[268]	[237,494,214,293]	6	hSpCas9	negative selection	8260610
74683472	74683495	14	+	27260156	PANC1	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.04767623974970703	[256]	[288,242,282,114]	0	hSpCas9	negative selection	8260611
74675709	74675732	14	+	27260156	PANC1	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.3346580133738066	[609]	[785,961,366,585]	5	hSpCas9	negative selection	8260612
74692293	74692316	14	+	27260156	PANC1	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.05916040554603047	[572]	[636,563,335,374]	-1	hSpCas9	negative selection	8282532
74683392	74683415	14	-	27260156	PANC1	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3426396037994839	[269]	[292,270,435,185]	5	hSpCas9	negative selection	8282533
74692255	74692278	14	+	27260156	PANC1	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.36982268665813994	[479]	[655,692,360,453]	6	hSpCas9	negative selection	8282534
74683449	74683472	14	-	27260156	PANC0813	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.028347029365456633	[865]	[1010,979,993,1003]	0	hSpCas9	negative selection	8317577
74675891	74675914	14	+	27260156	PANC0813	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.19041635430034776	[378]	[416,330,516,302]	-3	hSpCas9	negative selection	8317578
74683392	74683415	14	-	27260156	PANC0813	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.3516524524313045	[269]	[302,238,265,193]	-5	hSpCas9	negative selection	8317579
74684542	74684565	14	-	27260156	PANC0813	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.5338438208999636	[511]	[435,476,532,227]	-7	hSpCas9	negative selection	8339528
74683449	74683472	14	-	27260156	PANC0813	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	-0.028347029365456633	[865]	[1010,979,993,1003]	0	hSpCas9	negative selection	8339529
74684612	74684635	14	+	27260156	PANC0813	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.14635433672200682	[326]	[368,365,350,305]	-2	hSpCas9	negative selection	8339530
74675698	74675721	14	-	27260156	PANC0813	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.2594782606091288	[268]	[268,254,217,310]	-4	hSpCas9	negative selection	8381861
74683472	74683495	14	+	27260156	PANC0813	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.03539701804665352	[256]	[299,342,317,276]	0	hSpCas9	negative selection	8381862
74675709	74675732	14	+	27260156	PANC0813	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.13140852912375262	[609]	[549,643,579,821]	-2	hSpCas9	negative selection	8381863
74692293	74692316	14	+	27260156	PANC0813	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.21527818695960366	[572]	[880,719,727,802]	3	hSpCas9	negative selection	8403783
74683392	74683415	14	-	27260156	PANC0813	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	-0.3516524524313045	[269]	[302,238,265,193]	-5	hSpCas9	negative selection	8403784
74692255	74692278	14	+	27260156	PANC0813	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.11932715132641908	[479]	[641,613,696,504]	2	hSpCas9	negative selection	8403785
74683449	74683472	14	-	27260156	RDES	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.07151687204410662	[865]	[948,1057,1049,1126]	1	hSpCas9	negative selection	8438828
74675891	74675914	14	+	27260156	RDES	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.2867864785869888	[378]	[282,327,339,508]	-5	hSpCas9	negative selection	8438829
74683392	74683415	14	-	27260156	RDES	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.2957047754147165	[269]	[281,310,424,551]	5	hSpCas9	negative selection	8438830
74684542	74684565	14	-	27260156	RDES	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.23447702373398788	[511]	[365,486,599,580]	-4	hSpCas9	negative selection	8460779
74683449	74683472	14	-	27260156	RDES	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.07151687204410662	[865]	[948,1057,1049,1126]	1	hSpCas9	negative selection	8460780
74684612	74684635	14	+	27260156	RDES	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.13098048925345612	[326]	[373,400,337,547]	2	hSpCas9	negative selection	8460781
74675698	74675721	14	-	27260156	RDES	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.09441440650789146	[268]	[312,228,272,341]	-1	hSpCas9	negative selection	8503112
74683472	74683495	14	+	27260156	RDES	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.2804871041468332	[256]	[298,231,456,485]	4	hSpCas9	negative selection	8503113
74675709	74675732	14	+	27260156	RDES	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.31043617077459656	[609]	[792,848,874,967]	5	hSpCas9	negative selection	8503114
74692293	74692316	14	+	27260156	RDES	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.21862197944128264	[572]	[458,603,602,608]	-4	hSpCas9	negative selection	8525034
74683392	74683415	14	-	27260156	RDES	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.2957047754147165	[269]	[281,310,424,551]	5	hSpCas9	negative selection	8525035
74692255	74692278	14	+	27260156	RDES	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.40931741040395475	[479]	[494,626,919,976]	6	hSpCas9	negative selection	8525036
74683449	74683472	14	-	27260156	PC3	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.39493981135709333	[865]	[569,1232,1750,1386]	8	hSpCas9	negative selection	8560079
74675891	74675914	14	+	27260156	PC3	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.17530299829011126	[378]	[179,321,715,307]	-4	hSpCas9	negative selection	8560080
74683392	74683415	14	-	27260156	PC3	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.33036630405741996	[269]	[246,189,625,417]	7	hSpCas9	negative selection	8560081
74684542	74684565	14	-	27260156	PC3	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	0.0298588116577488	[511]	[331,450,873,603]	0	hSpCas9	negative selection	8582030
74683449	74683472	14	-	27260156	PC3	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.39493981135709333	[865]	[569,1232,1750,1386]	8	hSpCas9	negative selection	8582031
74684612	74684635	14	+	27260156	PC3	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.4259718489067574	[326]	[374,330,719,411]	8	hSpCas9	negative selection	8582032
74675698	74675721	14	-	27260156	PC3	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.18067070723950163	[268]	[114,286,235,343]	-4	hSpCas9	negative selection	8624363
74683472	74683495	14	+	27260156	PC3	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.2680374807986634	[256]	[161,331,751,192]	6	hSpCas9	negative selection	8624364
74675709	74675732	14	+	27260156	PC3	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.0861444769002841	[609]	[424,701,1157,517]	2	hSpCas9	negative selection	8624365
74692293	74692316	14	+	27260156	PC3	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.1717448471188594	[572]	[350,550,953,350]	-4	hSpCas9	negative selection	8646285
74683392	74683415	14	-	27260156	PC3	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.33036630405741996	[269]	[246,189,625,417]	7	hSpCas9	negative selection	8646286
74692255	74692278	14	+	27260156	PC3	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.17614575952139064	[479]	[303,511,952,614]	4	hSpCas9	negative selection	8646287
74683449	74683472	14	-	27260156	PATU8988T	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.23418138897927665	[865]	[1187,1171,895,674]	4	hSpCas9	negative selection	8681330
74675891	74675914	14	+	27260156	PATU8988T	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	0.05456019588489597	[378]	[323,386,353,463]	0	hSpCas9	negative selection	8681331
74683392	74683415	14	-	27260156	PATU8988T	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.010047449087298377	[269]	[237,325,173,324]	0	hSpCas9	negative selection	8681332
74684542	74684565	14	-	27260156	PATU8988T	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.5930867131532821	[511]	[357,386,279,289]	-7	hSpCas9	negative selection	8703281
74683449	74683472	14	-	27260156	PATU8988T	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.23418138897927665	[865]	[1187,1171,895,674]	4	hSpCas9	negative selection	8703282
74684612	74684635	14	+	27260156	PATU8988T	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.09233458011201456	[326]	[261,225,388,300]	-2	hSpCas9	negative selection	8703283
74675698	74675721	14	-	27260156	PATU8988T	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.2021392213657791	[268]	[197,325,202,182]	-3	hSpCas9	negative selection	8745614
74683472	74683495	14	+	27260156	PATU8988T	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.06702066989345279	[256]	[256,378,173,144]	-1	hSpCas9	negative selection	8745615
74675709	74675732	14	+	27260156	PATU8988T	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.12395858591415954	[609]	[692,612,465,386]	-2	hSpCas9	negative selection	8745616
74692293	74692316	14	+	27260156	PATU8988T	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	0.44018862136323045	[572]	[528,865,905,708]	7	hSpCas9	negative selection	8767536
74683392	74683415	14	-	27260156	PATU8988T	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.010047449087298377	[269]	[237,325,173,324]	0	hSpCas9	negative selection	8767537
74692255	74692278	14	+	27260156	PATU8988T	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.22607900871465353	[479]	[407,642,533,598]	4	hSpCas9	negative selection	8767538
74683449	74683472	14	-	27260156	T47D	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.1659627609604294	[865]	[1268,1005,1063,1202]	3	hSpCas9	negative selection	8802581
74675891	74675914	14	+	27260156	T47D	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.3411929498649917	[378]	[321,353,289,430]	-6	hSpCas9	negative selection	8802582
74683392	74683415	14	-	27260156	T47D	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.36892138744000363	[269]	[409,430,395,384]	7	hSpCas9	negative selection	8802583
74684542	74684565	14	-	27260156	T47D	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.20166244537281036	[511]	[596,401,509,577]	-4	hSpCas9	negative selection	8824532
74683449	74683472	14	-	27260156	T47D	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.1659627609604294	[865]	[1268,1005,1063,1202]	3	hSpCas9	negative selection	8824533
74684612	74684635	14	+	27260156	T47D	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.0169763190774066	[326]	[414,362,343,385]	0	hSpCas9	negative selection	8824534
74675698	74675721	14	-	27260156	T47D	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.12499201494245749	[268]	[318,212,279,345]	-3	hSpCas9	negative selection	8866865
74683472	74683495	14	+	27260156	T47D	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.06145562119466219	[256]	[378,300,334,232]	1	hSpCas9	negative selection	8866866
74675709	74675732	14	+	27260156	T47D	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.13623246415095494	[609]	[728,539,665,660]	-3	hSpCas9	negative selection	8866867
74692293	74692316	14	+	27260156	T47D	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.09243095153594597	[572]	[644,624,601,632]	-2	hSpCas9	negative selection	8888787
74683392	74683415	14	-	27260156	T47D	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.36892138744000363	[269]	[409,430,395,384]	7	hSpCas9	negative selection	8888788
74692255	74692278	14	+	27260156	T47D	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.0643348345210401	[479]	[550,630,560,591]	1	hSpCas9	negative selection	8888789
74683449	74683472	14	-	27260156	SU8686	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.12882469024809284	[865]	[976,825,922,1049]	2	hSpCas9	negative selection	8923832
74675891	74675914	14	+	27260156	SU8686	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.3434591535970585	[378]	[227,322,277,368]	-5	hSpCas9	negative selection	8923833
74683392	74683415	14	-	27260156	SU8686	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.30446896140725266	[269]	[316,313,315,384]	5	hSpCas9	negative selection	8923834
74684542	74684565	14	-	27260156	SU8686	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.31902327623325505	[511]	[337,365,506,433]	-5	hSpCas9	negative selection	8945783
74683449	74683472	14	-	27260156	SU8686	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.12882469024809284	[865]	[976,825,922,1049]	2	hSpCas9	negative selection	8945784
74684612	74684635	14	+	27260156	SU8686	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.016755244578623096	[326]	[288,215,350,464]	0	hSpCas9	negative selection	8945785
74675698	74675721	14	-	27260156	SU8686	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.09259487344163286	[268]	[259,242,258,233]	-2	hSpCas9	negative selection	8988116
74683472	74683495	14	+	27260156	SU8686	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.030691450215105553	[256]	[172,270,281,281]	0	hSpCas9	negative selection	8988117
74675709	74675732	14	+	27260156	SU8686	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.08864748330661337	[609]	[515,668,708,694]	1	hSpCas9	negative selection	8988118
74692293	74692316	14	+	27260156	SU8686	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.09615127656737099	[572]	[479,488,524,659]	-2	hSpCas9	negative selection	9010038
74683392	74683415	14	-	27260156	SU8686	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.30446896140725266	[269]	[316,313,315,384]	5	hSpCas9	negative selection	9010039
74692255	74692278	14	+	27260156	SU8686	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.21889558190520245	[479]	[494,538,622,566]	4	hSpCas9	negative selection	9010040
74683449	74683472	14	-	27260156	SKES1	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.1796530931203827	[865]	[1253,910,1032,760]	4	hSpCas9	negative selection	9045083
74675891	74675914	14	+	27260156	SKES1	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.33962395729197603	[378]	[359,291,319,234]	-6	hSpCas9	negative selection	9045084
74683392	74683415	14	-	27260156	SKES1	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.1917987020890196	[269]	[305,260,253,390]	4	hSpCas9	negative selection	9045085
74684542	74684565	14	-	27260156	SKES1	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.11228589164690522	[511]	[558,399,514,419]	-2	hSpCas9	negative selection	9067034
74683449	74683472	14	-	27260156	SKES1	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.1796530931203827	[865]	[1253,910,1032,760]	4	hSpCas9	negative selection	9067035
74684612	74684635	14	+	27260156	SKES1	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.1978769415868643	[326]	[323,376,190,262]	-4	hSpCas9	negative selection	9067036
74675698	74675721	14	-	27260156	SKES1	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.08402014753357279	[268]	[281,361,261,242]	1	hSpCas9	negative selection	9109367
74683472	74683495	14	+	27260156	SKES1	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.03386840566472604	[256]	[367,323,188,196]	0	hSpCas9	negative selection	9109368
74675709	74675732	14	+	27260156	SKES1	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.004419529101906683	[609]	[597,628,766,444]	0	hSpCas9	negative selection	9109369
74692293	74692316	14	+	27260156	SKES1	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.16573673263572186	[572]	[493,545,575,427]	-4	hSpCas9	negative selection	9131289
74683392	74683415	14	-	27260156	SKES1	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.1917987020890196	[269]	[305,260,253,390]	4	hSpCas9	negative selection	9131290
74692255	74692278	14	+	27260156	SKES1	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.16887667866170902	[479]	[673,579,543,390]	3	hSpCas9	negative selection	9131291
74683449	74683472	14	-	27260156	TOV112D	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.24696009755233683	[865]	[989,1426,1126,675]	5	hSpCas9	negative selection	9166334
74675891	74675914	14	+	27260156	TOV112D	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.36169540442073544	[378]	[155,498,249,313]	-6	hSpCas9	negative selection	9166335
74683392	74683415	14	-	27260156	TOV112D	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3626065376506507	[269]	[258,374,391,362]	6	hSpCas9	negative selection	9166336
74684542	74684565	14	-	27260156	TOV112D	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.624983349350316	[511]	[301,483,165,409]	-8	hSpCas9	negative selection	9188285
74683449	74683472	14	-	27260156	TOV112D	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.24696009755233683	[865]	[989,1426,1126,675]	5	hSpCas9	negative selection	9188286
74684612	74684635	14	+	27260156	TOV112D	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.40711702367003544	[326]	[559,610,275,345]	7	hSpCas9	negative selection	9188287
74675698	74675721	14	-	27260156	TOV112D	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	-0.0776919890760146	[268]	[294,279,229,225]	-1	hSpCas9	negative selection	9230618
74683472	74683495	14	+	27260156	TOV112D	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.4183407256421069	[256]	[308,227,108,143]	-7	hSpCas9	negative selection	9230619
74675709	74675732	14	+	27260156	TOV112D	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	0.06577083190856842	[609]	[699,776,563,556]	1	hSpCas9	negative selection	9230620
74692293	74692316	14	+	27260156	TOV112D	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.15667866745019166	[572]	[418,801,527,375]	-3	hSpCas9	negative selection	9252540
74683392	74683415	14	-	27260156	TOV112D	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.3626065376506507	[269]	[258,374,391,362]	6	hSpCas9	negative selection	9252541
74692255	74692278	14	+	27260156	TOV112D	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.16446248629045168	[479]	[490,535,526,593]	3	hSpCas9	negative selection	9252542
74683449	74683472	14	-	27260156	TC71	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.10944710758871234	[865]	[862,1048,951,1155]	2	hSpCas9	negative selection	9287585
74675891	74675914	14	+	27260156	TC71	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.18599646704214035	[378]	[322,289,405,411]	-5	hSpCas9	negative selection	9287586
74683392	74683415	14	-	27260156	TC71	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.25030038712050207	[269]	[326,304,404,337]	6	hSpCas9	negative selection	9287587
74684542	74684565	14	-	27260156	TC71	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.3431382816010797	[511]	[420,407,464,435]	-7	hSpCas9	negative selection	9309536
74683449	74683472	14	-	27260156	TC71	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.10944710758871234	[865]	[862,1048,951,1155]	2	hSpCas9	negative selection	9309537
74684612	74684635	14	+	27260156	TC71	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.006660712951676695	[326]	[434,324,293,340]	0	hSpCas9	negative selection	9309538
74675698	74675721	14	-	27260156	TC71	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.15767242186541275	[268]	[290,304,285,411]	4	hSpCas9	negative selection	9351869
74683472	74683495	14	+	27260156	TC71	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.003994136352383326	[256]	[246,233,269,359]	0	hSpCas9	negative selection	9351870
74675709	74675732	14	+	27260156	TC71	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.07686541041188677	[609]	[576,588,516,812]	-2	hSpCas9	negative selection	9351871
74692293	74692316	14	+	27260156	TC71	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.0756374895568975	[572]	[433,544,613,750]	-2	hSpCas9	negative selection	9373791
74683392	74683415	14	-	27260156	TC71	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.25030038712050207	[269]	[326,304,404,337]	6	hSpCas9	negative selection	9373792
74692255	74692278	14	+	27260156	TC71	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	-0.03887168385425789	[479]	[497,473,444,593]	-1	hSpCas9	negative selection	9373793
74683449	74683472	14	-	27260156	TC32	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.12501526854452016	[865]	[919,641,1137,930]	2	hSpCas9	negative selection	9408836
74675891	74675914	14	+	27260156	TC32	viability	GTAAATGCTCACGCCTGAAGTGG	AREL1	ENSG00000119682	-0.24836848782277698	[378]	[156,368,322,327]	-4	hSpCas9	negative selection	9408837
74683392	74683415	14	-	27260156	TC32	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.16181123150265675	[269]	[237,246,373,294]	3	hSpCas9	negative selection	9408838
74684542	74684565	14	-	27260156	TC32	viability	ACTATTTATGACTACGTGCGGGG	AREL1	ENSG00000119682	-0.6175675920042277	[511]	[235,208,494,381]	-8	hSpCas9	negative selection	9430787
74683449	74683472	14	-	27260156	TC32	viability	CTCTCATGTCGAGCTAGCAGTGG	AREL1	ENSG00000119682	0.12501526854452016	[865]	[919,641,1137,930]	2	hSpCas9	negative selection	9430788
74684612	74684635	14	+	27260156	TC32	viability	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	-0.05481331917252308	[326]	[247,276,355,307]	-1	hSpCas9	negative selection	9430789
74675698	74675721	14	-	27260156	TC32	viability	GTACTGCTATGTGTCACCAAAGG	AREL1	ENSG00000119682	0.00803930767415495	[268]	[233,180,384,254]	0	hSpCas9	negative selection	9473120
74683472	74683495	14	+	27260156	TC32	viability	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.23500829898980968	[256]	[275,177,505,237]	4	hSpCas9	negative selection	9473121
74675709	74675732	14	+	27260156	TC32	viability	ACATAGCAGTACACCTTCTTCGG	AREL1	ENSG00000119682	-0.3539007635126702	[609]	[419,259,726,487]	-6	hSpCas9	negative selection	9473122
74692293	74692316	14	+	27260156	TC32	viability	AGGGTGCAATCGACTGCCAAAGG	AREL1	ENSG00000119682	-0.13784275213988817	[572]	[553,227,642,630]	-2	hSpCas9	negative selection	9495042
74683392	74683415	14	-	27260156	TC32	viability	CAATTCCAACGTAGTAAAAGTGG	AREL1	ENSG00000119682	0.16181123150265675	[269]	[237,246,373,294]	3	hSpCas9	negative selection	9495043
74692255	74692278	14	+	27260156	TC32	viability	GCCCAAGAATATATCATTCCTGG	AREL1	ENSG00000119682	0.2795234267330084	[479]	[383,572,652,575]	5	hSpCas9	negative selection	9495044
74673127	74673150	14	+	27869803	HPAFII	viability after 27 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-0.6555865326838385	[145]	[75,25,NaN]	-5	hSpCas9	negative selection	9552372
74674054	74674077	14	+	27869803	HPAFII	viability after 27 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.7043831822284847	[162]	[71,195,NaN]	6	hSpCas9	negative selection	9552373
74675782	74675805	14	-	27869803	HPAFII	viability after 27 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-1.7648647013546142	[408]	[29,90,NaN]	-8	hSpCas9	negative selection	9552374
74676673	74676696	14	+	27869803	HPAFII	viability after 27 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	0.010042614567676633	[50]	[38,16,NaN]	0	hSpCas9	negative selection	9552375
74683472	74683495	14	+	27869803	HPAFII	viability after 27 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.6479553486946824	[96]	[104,58,NaN]	5	hSpCas9	negative selection	9552376
74684612	74684635	14	+	27869803	HPAFII	viability after 27 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.46752469770535837	[288]	[124,280,NaN]	4	hSpCas9	negative selection	9552377
74673127	74673150	14	+	27869803	HPAFII	viability after 15 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-0.6548704965082334	[145]	[193,40,NaN]	-6	hSpCas9	negative selection	9634821
74674054	74674077	14	+	27869803	HPAFII	viability after 15 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.5085171439749026	[162]	[181,290,NaN]	6	hSpCas9	negative selection	9634822
74675782	74675805	14	-	27869803	HPAFII	viability after 15 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-1.2702332368966909	[408]	[254,136,NaN]	-8	hSpCas9	negative selection	9634823
74676673	74676696	14	+	27869803	HPAFII	viability after 15 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	0.9936075527625685	[50]	[155,79,NaN]	9	hSpCas9	negative selection	9634824
74683472	74683495	14	+	27869803	HPAFII	viability after 15 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.45270073358269436	[96]	[228,88,NaN]	5	hSpCas9	negative selection	9634825
74684612	74684635	14	+	27869803	HPAFII	viability after 15 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.3534080757444375	[288]	[336,433,NaN]	4	hSpCas9	negative selection	9634826
74673127	74673150	14	+	27869803	ASPC1	viability after 36 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	0.11629682867719626	[354]	[58,196,135]	1	hSpCas9	negative selection	9717270
74674054	74674077	14	+	27869803	ASPC1	viability after 36 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-0.9338793888201721	[370]	[110,35,61]	-7	hSpCas9	negative selection	9717271
74675782	74675805	14	-	27869803	ASPC1	viability after 36 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.23464558515134099	[841]	[298,326,389]	2	hSpCas9	negative selection	9717272
74676673	74676696	14	+	27869803	ASPC1	viability after 36 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-2.3673787963783472	[228]	[0,0,36]	-9	hSpCas9	negative selection	9717273
74683472	74683495	14	+	27869803	ASPC1	viability after 36 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.07249676380594772	[218]	[43,34,121]	0	hSpCas9	negative selection	9717274
74684612	74684635	14	+	27869803	ASPC1	viability after 36 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.22188692446143787	[766]	[146,587,205]	2	hSpCas9	negative selection	9717275
74673127	74673150	14	+	27869803	PATU8988S	viability after 35 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-0.41891962390804627	[296]	[76,101,NaN]	-4	hSpCas9	negative selection	9799719
74674054	74674077	14	+	27869803	PATU8988S	viability after 35 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.11556816594677088	[252]	[63,156,NaN]	1	hSpCas9	negative selection	9799720
74675782	74675805	14	-	27869803	PATU8988S	viability after 35 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.12714589964968148	[557]	[218,271,NaN]	1	hSpCas9	negative selection	9799721
74676673	74676696	14	+	27869803	PATU8988S	viability after 35 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-1.3620377781274364	[184]	[22,34,NaN]	-8	hSpCas9	negative selection	9799722
74683472	74683495	14	+	27869803	PATU8988S	viability after 35 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.30002440202261527	[245]	[68,91,NaN]	-3	hSpCas9	negative selection	9799723
74684612	74684635	14	+	27869803	PATU8988S	viability after 35 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.5561784104788468	[679]	[266,538,NaN]	6	hSpCas9	negative selection	9799724
74673127	74673150	14	+	27869803	PATU8988S	viability after 31 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-0.5296218634355828	[296]	[74,90,NaN]	-5	hSpCas9	negative selection	9882168
74674054	74674077	14	+	27869803	PATU8988S	viability after 31 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-0.8451462282800501	[252]	[38,77,NaN]	-7	hSpCas9	negative selection	9882169
74675782	74675805	14	-	27869803	PATU8988S	viability after 31 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	0.7709698764014462	[557]	[358,405,NaN]	8	hSpCas9	negative selection	9882170
74676673	74676696	14	+	27869803	PATU8988S	viability after 31 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.4059374245588878	[184]	[34,81,NaN]	-4	hSpCas9	negative selection	9882171
74683472	74683495	14	+	27869803	PATU8988S	viability after 31 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	-0.7217519722944099	[245]	[51,68,NaN]	-6	hSpCas9	negative selection	9882172
74684612	74684635	14	+	27869803	PATU8988S	viability after 31 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.33869268181546813	[679]	[213,506,NaN]	4	hSpCas9	negative selection	9882173
74673127	74673150	14	+	27869803	HPAFII	viability after 35 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-1.2870359902134214	[145]	[18,42,NaN]	-6	hSpCas9	negative selection	9964617
74674054	74674077	14	+	27869803	HPAFII	viability after 35 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.5443319027135944	[162]	[93,149,NaN]	3	hSpCas9	negative selection	9964618
74675782	74675805	14	-	27869803	HPAFII	viability after 35 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-1.4406235805715892	[408]	[48,106,NaN]	-6	hSpCas9	negative selection	9964619
74676673	74676696	14	+	27869803	HPAFII	viability after 35 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-0.3641382567092295	[50]	[20,18,NaN]	-2	hSpCas9	negative selection	9964620
74683472	74683495	14	+	27869803	HPAFII	viability after 35 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.9297103996915285	[96]	[117,65,NaN]	6	hSpCas9	negative selection	9964621
74684612	74684635	14	+	27869803	HPAFII	viability after 35 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.7383675382566424	[288]	[165,331,NaN]	5	hSpCas9	negative selection	9964622
74673127	74673150	14	+	27869803	HPAFII	viability after 31 days	TCCTTACAGCTGAGCTCCACAGG	AREL1	ENSG00000119682	-1.2968385029075367	[145]	[29,36,NaN]	-7	hSpCas9	negative selection	10047066
74674054	74674077	14	+	27869803	HPAFII	viability after 31 days	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.09123332581470778	[162]	[73,122,NaN]	0	hSpCas9	negative selection	10047067
74675782	74675805	14	-	27869803	HPAFII	viability after 31 days	GCCATCCACTGCTGTTGACGAGG	AREL1	ENSG00000119682	-1.9651921349024692	[408]	[53,63,NaN]	-8	hSpCas9	negative selection	10047068
74676673	74676696	14	+	27869803	HPAFII	viability after 31 days	AAGGGTGTGCGGCTGCCCACAGG	AREL1	ENSG00000119682	-1.0412999905209097	[50]	[22,3,NaN]	-6	hSpCas9	negative selection	10047069
74683472	74683495	14	+	27869803	HPAFII	viability after 31 days	ATGTGAACTCTTAGTCCCACAGG	AREL1	ENSG00000119682	0.8126126395084603	[96]	[86,104,NaN]	6	hSpCas9	negative selection	10047070
74684612	74684635	14	+	27869803	HPAFII	viability after 31 days	CACGTGCGGCAAGCTCAAAGAGG	AREL1	ENSG00000119682	0.6394010988178935	[288]	[199,309,NaN]	5	hSpCas9	negative selection	10047071
74684506	74684529	14	+	28162770	P31FUJ	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.20971603128657212	[272]	[370]	2	hSpCas9	negative selection	10112643
74676641	74676664	14	+	28162770	P31FUJ	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	-0.08131445122874237	[279]	[310]	-1	hSpCas9	negative selection	10112644
74684456	74684479	14	+	28162770	P31FUJ	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.22239242133644802	[185]	[254]	2	hSpCas9	negative selection	10112645
74675740	74675763	14	-	28162770	P31FUJ	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	-0.5754667574985364	[472]	[372]	-5	hSpCas9	negative selection	10112646
74675722	74675745	14	-	28162770	P31FUJ	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	-0.2521675292813097	[74]	[73]	-2	hSpCas9	negative selection	10112647
74674054	74674077	14	+	28162770	P31FUJ	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-0.015128331980460263	[349]	[406]	0	hSpCas9	negative selection	10112648
74673167	74673190	14	-	28162770	P31FUJ	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.4093042034103861	[329]	[514]	4	hSpCas9	negative selection	10112649
74663962	74663985	14	+	28162770	P31FUJ	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	-0.5743106682712573	[203]	[160]	-5	hSpCas9	negative selection	10112650
74684572	74684595	14	-	28162770	P31FUJ	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	0.5008043776619129	[257]	[428]	5	hSpCas9	negative selection	10112651
74684480	74684503	14	-	28162770	P31FUJ	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.44292576022995983	[153]	[245]	5	hSpCas9	negative selection	10112652
74684506	74684529	14	+	28162770	TF1	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10282009
74676641	74676664	14	+	28162770	TF1	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	NaN	[NaN]	[183]	1	hSpCas9	negative selection	10282010
74684456	74684479	14	+	28162770	TF1	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10282011
74675740	74675763	14	-	28162770	TF1	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	NaN	[NaN]	[484]	1	hSpCas9	negative selection	10282012
74675722	74675745	14	-	28162770	TF1	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10282013
74674054	74674077	14	+	28162770	TF1	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	NaN	[NaN]	[244]	1	hSpCas9	negative selection	10282014
74673167	74673190	14	-	28162770	TF1	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10282015
74663962	74663985	14	+	28162770	TF1	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	NaN	[NaN]	[99]	1	hSpCas9	negative selection	10282016
74684572	74684595	14	-	28162770	TF1	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	NaN	[NaN]	[401]	1	hSpCas9	negative selection	10282017
74684480	74684503	14	-	28162770	TF1	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	NaN	[NaN]	[149]	1	hSpCas9	negative selection	10282018
74684506	74684529	14	+	28162770	SKM1	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	1.6015978147602623	[62]	[337]	9	hSpCas9	negative selection	10451375
74676641	74676664	14	+	28162770	SKM1	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	0.8978903827852592	[50]	[167]	8	hSpCas9	negative selection	10451376
74684456	74684479	14	+	28162770	SKM1	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.4003907233144425	[47]	[111]	4	hSpCas9	negative selection	10451377
74675740	74675763	14	-	28162770	SKM1	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	-0.10341463317065402	[157]	[259]	-1	hSpCas9	negative selection	10451378
74675722	74675745	14	-	28162770	SKM1	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	0.046753768699742126	[22]	[41]	0	hSpCas9	negative selection	10451379
74674054	74674077	14	+	28162770	SKM1	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.8702375390172261	[94]	[306]	8	hSpCas9	negative selection	10451380
74673167	74673190	14	-	28162770	SKM1	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.4683908234322501	[73]	[180]	4	hSpCas9	negative selection	10451381
74663962	74663985	14	+	28162770	SKM1	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	1.6146380557420492	[28]	[156]	9	hSpCas9	negative selection	10451382
74684572	74684595	14	-	28162770	SKM1	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	1.2654611432283338	[55]	[237]	9	hSpCas9	negative selection	10451383
74684480	74684503	14	-	28162770	SKM1	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.4562994644650989	[46]	[113]	4	hSpCas9	negative selection	10451384
74684506	74684529	14	+	28162770	SKM1	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	1.6015978147602623	[62]	[337]	9	hSpCas9	negative selection	10620741
74676641	74676664	14	+	28162770	SKM1	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	0.8978903827852592	[50]	[167]	8	hSpCas9	negative selection	10620742
74684456	74684479	14	+	28162770	SKM1	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.4003907233144425	[47]	[111]	4	hSpCas9	negative selection	10620743
74675740	74675763	14	-	28162770	SKM1	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	-0.10341463317065402	[157]	[259]	-1	hSpCas9	negative selection	10620744
74675722	74675745	14	-	28162770	SKM1	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	0.046753768699742126	[22]	[41]	0	hSpCas9	negative selection	10620745
74674054	74674077	14	+	28162770	SKM1	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.8702375390172261	[94]	[306]	8	hSpCas9	negative selection	10620746
74673167	74673190	14	-	28162770	SKM1	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.4683908234322501	[73]	[180]	4	hSpCas9	negative selection	10620747
74663962	74663985	14	+	28162770	SKM1	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	1.6146380557420492	[28]	[156]	9	hSpCas9	negative selection	10620748
74684572	74684595	14	-	28162770	SKM1	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	1.2654611432283338	[55]	[237]	9	hSpCas9	negative selection	10620749
74684480	74684503	14	-	28162770	SKM1	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.4562994644650989	[46]	[113]	4	hSpCas9	negative selection	10620750
74684506	74684529	14	+	28162770	PL21	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	-0.4005902020901527	[275]	[90]	-3	hSpCas9	negative selection	10790107
74676641	74676664	14	+	28162770	PL21	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	0.47040558955418965	[198]	[119]	4	hSpCas9	negative selection	10790108
74684456	74684479	14	+	28162770	PL21	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.23820765532283958	[186]	[95]	2	hSpCas9	negative selection	10790109
74675740	74675763	14	-	28162770	PL21	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	1.0501141704847123	[485]	[437]	8	hSpCas9	negative selection	10790110
74675722	74675745	14	-	28162770	PL21	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	0.17265887806721336	[52]	[25]	1	hSpCas9	negative selection	10790111
74674054	74674077	14	+	28162770	PL21	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.4111632217465707	[272]	[157]	3	hSpCas9	negative selection	10790112
74673167	74673190	14	-	28162770	PL21	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	-0.0353089596725743	[258]	[109]	0	hSpCas9	negative selection	10790113
74663962	74663985	14	+	28162770	PL21	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	0.9326593036243345	[129]	[107]	7	hSpCas9	negative selection	10790114
74684572	74684595	14	-	28162770	PL21	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	1.6066151002647397	[168]	[223]	9	hSpCas9	negative selection	10790115
74684480	74684503	14	-	28162770	PL21	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	-0.7718460093410832	[101]	[25]	-5	hSpCas9	negative selection	10790116
74684506	74684529	14	+	28162770	P31FUJ	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.20971603128657212	[272]	[370]	2	hSpCas9	negative selection	10959473
74676641	74676664	14	+	28162770	P31FUJ	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	-0.08131445122874237	[279]	[310]	-1	hSpCas9	negative selection	10959474
74684456	74684479	14	+	28162770	P31FUJ	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.22239242133644802	[185]	[254]	2	hSpCas9	negative selection	10959475
74675740	74675763	14	-	28162770	P31FUJ	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	-0.5754667574985364	[472]	[372]	-5	hSpCas9	negative selection	10959476
74675722	74675745	14	-	28162770	P31FUJ	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	-0.2521675292813097	[74]	[73]	-2	hSpCas9	negative selection	10959477
74674054	74674077	14	+	28162770	P31FUJ	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	-0.015128331980460263	[349]	[406]	0	hSpCas9	negative selection	10959478
74673167	74673190	14	-	28162770	P31FUJ	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.4093042034103861	[329]	[514]	4	hSpCas9	negative selection	10959479
74663962	74663985	14	+	28162770	P31FUJ	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	-0.5743106682712573	[203]	[160]	-5	hSpCas9	negative selection	10959480
74684572	74684595	14	-	28162770	P31FUJ	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	0.5008043776619129	[257]	[428]	5	hSpCas9	negative selection	10959481
74684480	74684503	14	-	28162770	P31FUJ	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.44292576022995983	[153]	[245]	5	hSpCas9	negative selection	10959482
74684506	74684529	14	+	28162770	OCIAML5	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.5454125570305421	[92]	[244]	5	hSpCas9	negative selection	11128839
74676641	74676664	14	+	28162770	OCIAML5	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	0.03590681140189167	[173]	[321]	0	hSpCas9	negative selection	11128840
74684456	74684479	14	+	28162770	OCIAML5	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	-0.026095970639045674	[131]	[233]	0	hSpCas9	negative selection	11128841
74675740	74675763	14	-	28162770	OCIAML5	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	0.14334615964035113	[314]	[627]	1	hSpCas9	negative selection	11128842
74675722	74675745	14	-	28162770	OCIAML5	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	-0.24720451270513588	[47]	[72]	-2	hSpCas9	negative selection	11128843
74674054	74674077	14	+	28162770	OCIAML5	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.3269894423304438	[139]	[316]	2	hSpCas9	negative selection	11128844
74673167	74673190	14	-	28162770	OCIAML5	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.3276394513709007	[146]	[332]	2	hSpCas9	negative selection	11128845
74663962	74663985	14	+	28162770	OCIAML5	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	0.925541007799555	[48]	[167]	7	hSpCas9	negative selection	11128846
74684572	74684595	14	-	28162770	OCIAML5	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	0.07052892545039618	[133]	[253]	0	hSpCas9	negative selection	11128847
74684480	74684503	14	-	28162770	OCIAML5	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	-0.014123328972969862	[79]	[142]	0	hSpCas9	negative selection	11128848
74684506	74684529	14	+	28162770	EOL1	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	-0.13881428942689478	[511]	[244]	-1	hSpCas9	negative selection	11298205
74676641	74676664	14	+	28162770	EOL1	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	-0.35487559480229214	[300]	[123]	-3	hSpCas9	negative selection	11298206
74684456	74684479	14	+	28162770	EOL1	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	-0.0011048869693842667	[415]	[218]	0	hSpCas9	negative selection	11298207
74675740	74675763	14	-	28162770	EOL1	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	0.20612858016214552	[978]	[594]	1	hSpCas9	negative selection	11298208
74675722	74675745	14	-	28162770	EOL1	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	1.440005761993737	[162]	[232]	9	hSpCas9	negative selection	11298209
74674054	74674077	14	+	28162770	EOL1	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.3212067415345238	[473]	[311]	3	hSpCas9	negative selection	11298210
74673167	74673190	14	-	28162770	EOL1	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.26236576838748277	[306]	[193]	2	hSpCas9	negative selection	11298211
74663962	74663985	14	+	28162770	EOL1	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	0.3931663110542224	[184]	[127]	3	hSpCas9	negative selection	11298212
74684572	74684595	14	-	28162770	EOL1	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	-0.5245829263767172	[313]	[114]	-4	hSpCas9	negative selection	11298213
74684480	74684503	14	-	28162770	EOL1	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	-1.1994409457049189	[169]	[38]	-7	hSpCas9	negative selection	11298214
74684506	74684529	14	+	28162770	MOLM13	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	-0.7900917965629295	[341]	[142]	-4	hSpCas9	negative selection	11467571
74676641	74676664	14	+	28162770	MOLM13	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	-0.8263719707265228	[438]	[178]	-4	hSpCas9	negative selection	11467572
74684456	74684479	14	+	28162770	MOLM13	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.6424628865649565	[240]	[271]	5	hSpCas9	negative selection	11467573
74675740	74675763	14	-	28162770	MOLM13	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	-0.3129013586650222	[712]	[414]	-2	hSpCas9	negative selection	11467574
74675722	74675745	14	-	28162770	MOLM13	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	1.8346717122162013	[132]	[342]	9	hSpCas9	negative selection	11467575
74674054	74674077	14	+	28162770	MOLM13	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	1.0723744405305535	[366]	[557]	7	hSpCas9	negative selection	11467576
74673167	74673190	14	-	28162770	MOLM13	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.2219791535019941	[267]	[225]	1	hSpCas9	negative selection	11467577
74663962	74663985	14	+	28162770	MOLM13	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	-0.5321106184554213	[147]	[73]	-3	hSpCas9	negative selection	11467578
74684572	74684595	14	-	28162770	MOLM13	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	0.44903035429326293	[307]	[303]	3	hSpCas9	negative selection	11467579
74684480	74684503	14	-	28162770	MOLM13	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.1741581784878684	[151]	[123]	1	hSpCas9	negative selection	11467580
74684506	74684529	14	+	28162770	HEL	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	1.0093359762214476	[317]	[409]	8	hSpCas9	negative selection	11636937
74676641	74676664	14	+	28162770	HEL	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	0.10642549398691711	[276]	[190]	0	hSpCas9	negative selection	11636938
74684456	74684479	14	+	28162770	HEL	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	-0.2367275026921543	[240]	[130]	-2	hSpCas9	negative selection	11636939
74675740	74675763	14	-	28162770	HEL	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	0.5738673317512122	[664]	[633]	5	hSpCas9	negative selection	11636940
74675722	74675745	14	-	28162770	HEL	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	0.39881324911426774	[89]	[75]	3	hSpCas9	negative selection	11636941
74674054	74674077	14	+	28162770	HEL	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.4774304586284147	[350]	[312]	4	hSpCas9	negative selection	11636942
74673167	74673190	14	-	28162770	HEL	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.47785444725857484	[249]	[222]	4	hSpCas9	negative selection	11636943
74663962	74663985	14	+	28162770	HEL	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	-0.16729022435557273	[134]	[76]	-1	hSpCas9	negative selection	11636944
74684572	74684595	14	-	28162770	HEL	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	0.7545296574579134	[210]	[227]	6	hSpCas9	negative selection	11636945
74684480	74684503	14	-	28162770	HEL	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.41717913158522596	[151]	[129]	3	hSpCas9	negative selection	11636946
74684506	74684529	14	+	28162770	MV411	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	-0.6666322704300486	[276]	[146]	-5	hSpCas9	negative selection	11806303
74676641	74676664	14	+	28162770	MV411	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	0.4721438379574697	[266]	[311]	4	hSpCas9	negative selection	11806304
74684456	74684479	14	+	28162770	MV411	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	-0.06791789018110089	[218]	[175]	0	hSpCas9	negative selection	11806305
74675740	74675763	14	-	28162770	MV411	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	0.8851175702182978	[411]	[640]	7	hSpCas9	negative selection	11806306
74675722	74675745	14	-	28162770	MV411	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	-0.6884321117975092	[87]	[45]	-5	hSpCas9	negative selection	11806307
74674054	74674077	14	+	28162770	MV411	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.13097857419539238	[244]	[225]	1	hSpCas9	negative selection	11806308
74673167	74673190	14	-	28162770	MV411	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	0.04645049304959842	[222]	[193]	0	hSpCas9	negative selection	11806309
74663962	74663985	14	+	28162770	MV411	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	-0.4804829037804238	[158]	[95]	-4	hSpCas9	negative selection	11806310
74684572	74684595	14	-	28162770	MV411	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	0.7353013633988501	[168]	[236]	6	hSpCas9	negative selection	11806311
74684480	74684503	14	-	28162770	MV411	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.21799377289029365	[98]	[96]	2	hSpCas9	negative selection	11806312
74684506	74684529	14	+	28162770	MONOMAC1	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.2548374203996616	[173]	[237]	2	hSpCas9	negative selection	11975669
74676641	74676664	14	+	28162770	MONOMAC1	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	-0.24465486729229327	[153]	[148]	-2	hSpCas9	negative selection	11975670
74684456	74684479	14	+	28162770	MONOMAC1	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	-0.7012680756678529	[138]	[97]	-5	hSpCas9	negative selection	11975671
74675740	74675763	14	-	28162770	MONOMAC1	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	0.47006394023208076	[329]	[523]	4	hSpCas9	negative selection	11975672
74675722	74675745	14	-	28162770	MONOMAC1	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	-0.7589157346676687	[61]	[41]	-6	hSpCas9	negative selection	11975673
74674054	74674077	14	+	28162770	MONOMAC1	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.5271425921508092	[203]	[336]	5	hSpCas9	negative selection	11975674
74673167	74673190	14	-	28162770	MONOMAC1	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	-0.5148952776378692	[176]	[141]	-4	hSpCas9	negative selection	11975675
74663962	74663985	14	+	28162770	MONOMAC1	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	0.23235594519636021	[74]	[100]	2	hSpCas9	negative selection	11975676
74684572	74684595	14	-	28162770	MONOMAC1	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	-0.3143937976977126	[127]	[117]	-3	hSpCas9	negative selection	11975677
74684480	74684503	14	-	28162770	MONOMAC1	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.5358590827976054	[70]	[117]	5	hSpCas9	negative selection	11975678
74684506	74684529	14	+	28162770	OCIAML2	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.5980829248418529	[40]	[343]	6	hSpCas9	negative selection	12145035
74676641	74676664	14	+	28162770	OCIAML2	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	-0.055592325963317396	[29]	[159]	0	hSpCas9	negative selection	12145036
74684456	74684479	14	+	28162770	OCIAML2	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.3440670721566108	[27]	[196]	3	hSpCas9	negative selection	12145037
74675740	74675763	14	-	28162770	OCIAML2	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	0.4095928199042773	[90]	[669]	4	hSpCas9	negative selection	12145038
74675722	74675745	14	-	28162770	OCIAML2	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	1.0093631158774523	[18]	[211]	8	hSpCas9	negative selection	12145039
74674054	74674077	14	+	28162770	OCIAML2	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.39498449478783826	[51]	[378]	4	hSpCas9	negative selection	12145040
74673167	74673190	14	-	28162770	OCIAML2	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	-0.41788836317018785	[46]	[194]	-3	hSpCas9	negative selection	12145041
74663962	74663985	14	+	28162770	OCIAML2	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	0.1001188162592942	[16]	[100]	0	hSpCas9	negative selection	12145042
74684572	74684595	14	-	28162770	OCIAML2	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	-0.33598029854737926	[45]	[201]	-3	hSpCas9	negative selection	12145043
74684480	74684503	14	-	28162770	OCIAML2	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	0.6762115630871096	[13]	[123]	6	hSpCas9	negative selection	12145044
74684506	74684529	14	+	28162770	OCIAML3	viability	CAGGAGACTTTGCAAGACCGGGG	AREL1	ENSG00000119682	0.5920886517892948	[68]	[313]	5	hSpCas9	negative selection	12314401
74676641	74676664	14	+	28162770	OCIAML3	viability	GGATTATCATACTCATCTCGGGG	AREL1	ENSG00000119682	-0.2803471614204014	[69]	[173]	-2	hSpCas9	negative selection	12314402
74684456	74684479	14	+	28162770	OCIAML3	viability	GCACTCGGAAGGCCATGCTGTGG	AREL1	ENSG00000119682	0.7097731078529399	[31]	[157]	6	hSpCas9	negative selection	12314403
74675740	74675763	14	-	28162770	OCIAML3	viability	TGAGTGCCACACCCCTGAGAAGG	AREL1	ENSG00000119682	0.30762722983286017	[109]	[410]	3	hSpCas9	negative selection	12314404
74675722	74675745	14	-	28162770	OCIAML3	viability	GAAGGTGAAGAAACCGAAGAAGG	AREL1	ENSG00000119682	0.47638168756723476	[19]	[83]	4	hSpCas9	negative selection	12314405
74674054	74674077	14	+	28162770	OCIAML3	viability	GGAAGGTGTAAAGGCGCCAGGGG	AREL1	ENSG00000119682	0.06895737239826616	[83]	[265]	0	hSpCas9	negative selection	12314406
74673167	74673190	14	-	28162770	OCIAML3	viability	TAAGCTGCTCACACTGGTGGTGG	AREL1	ENSG00000119682	-0.6464750602182987	[69]	[134]	-5	hSpCas9	negative selection	12314407
74663962	74663985	14	+	28162770	OCIAML3	viability	AGGGCGGCAAAGCCTCCAGGTGG	AREL1	ENSG00000119682	-0.15148940462321225	[38]	[105]	-1	hSpCas9	negative selection	12314408
74684572	74684595	14	-	28162770	OCIAML3	viability	AATGAGGACCGCGAGCGCCGAGG	AREL1	ENSG00000119682	0.2665893030104204	[56]	[206]	2	hSpCas9	negative selection	12314409
74684480	74684503	14	-	28162770	OCIAML3	viability	TTGGAAGGACCCCTATGAGGTGG	AREL1	ENSG00000119682	-0.27949701699928386	[38]	[96]	-2	hSpCas9	negative selection	12314410