Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:538
• Symbol:ATP7A
• Description:ATPase copper transporting alpha

DataSource: http://genomecrispr.dkfz.de/#!/results/ATP7A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
77989623	77989646	X	+	26472758	Jiyoye	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	4.550133335347916	[5]	[105]	9	hSpCas9	negative selection	12755
77989915	77989938	X	+	26472758	Jiyoye	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	1.1956712763121615	[32]	[56]	7	hSpCas9	negative selection	12756
77998566	77998589	X	+	26472758	Jiyoye	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	-0.5257104226355898	[20]	[10]	-4	hSpCas9	negative selection	12757
78011527	78011550	X	-	26472758	Jiyoye	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.2510561795885915	[38]	[34]	2	hSpCas9	negative selection	12758
78012967	78012990	X	-	26472758	Jiyoye	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	-1.3455732099012603	[336]	[99]	-7	hSpCas9	negative selection	12759
78013091	78013114	X	+	26472758	Jiyoye	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	-3.7892218312976302	[164]	[8]	-9	hSpCas9	negative selection	12760
78033604	78033627	X	+	26472758	Jiyoye	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	-2.324230687318432	[258]	[38]	-8	hSpCas9	negative selection	12761
78042656	78042679	X	+	26472758	Jiyoye	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	12762
78045482	78045505	X	-	26472758	Jiyoye	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	-0.8587186784671611	[100]	[41]	-6	hSpCas9	negative selection	12763
77988359	77988382	X	-	26472758	Jiyoye	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.1023207999774526	[104]	[84]	0	hSpCas9	negative selection	12764
77989623	77989646	X	+	26472758	KBM7	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.8660248586723989	[269,187]	[200,186]	8	hSpCas9	negative selection	203873
77989915	77989938	X	+	26472758	KBM7	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.015141158803222754	[286,224]	[40,191]	0	hSpCas9	negative selection	203874
77998566	77998589	X	+	26472758	KBM7	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	-0.0407527271718271	[94,87]	[34,47]	0	hSpCas9	negative selection	203875
78011527	78011550	X	-	26472758	KBM7	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.06664246751506128	[581,397]	[344,141]	0	hSpCas9	negative selection	203876
78012967	78012990	X	-	26472758	KBM7	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.3932279989768701	[1255,901]	[679,638]	4	hSpCas9	negative selection	203877
78013091	78013114	X	+	26472758	KBM7	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.40081381183084863	[153,257]	[144,119]	4	hSpCas9	negative selection	203878
78033604	78033627	X	+	26472758	KBM7	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	0.7248277585649443	[754,601]	[575,476]	7	hSpCas9	negative selection	203879
78042656	78042679	X	+	26472758	KBM7	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	0.12335733746955801	[71,28]	[17,30]	1	hSpCas9	negative selection	203880
78045482	78045505	X	-	26472758	KBM7	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	0.4980909504670574	[193,273]	[151,164]	5	hSpCas9	negative selection	203881
77988359	77988382	X	-	26472758	KBM7	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.6781575519818619	[655,413]	[599,211]	7	hSpCas9	negative selection	203882
77989623	77989646	X	+	26472758	Raji	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.6048831948444164	[118]	[41]	6	hSpCas9	negative selection	394991
77989915	77989938	X	+	26472758	Raji	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.252581450913535	[169]	[46]	2	hSpCas9	negative selection	394992
77998566	77998589	X	+	26472758	Raji	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	0.029381023372326176	[37]	[8]	0	hSpCas9	negative selection	394993
78011527	78011550	X	-	26472758	Raji	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.031032649243484645	[290]	[68]	0	hSpCas9	negative selection	394994
78012967	78012990	X	-	26472758	Raji	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.2572789658566583	[410]	[113]	2	hSpCas9	negative selection	394995
78013091	78013114	X	+	26472758	Raji	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	-0.4451574876551794	[87]	[14]	-4	hSpCas9	negative selection	394996
78033604	78033627	X	+	26472758	Raji	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	0.6464790273374267	[244]	[88]	6	hSpCas9	negative selection	394997
78042656	78042679	X	+	26472758	Raji	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	1.6923460360947558	[7]	[5]	9	hSpCas9	negative selection	394998
78045482	78045505	X	-	26472758	Raji	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	1.544788847680898	[95]	[64]	9	hSpCas9	negative selection	394999
77988359	77988382	X	-	26472758	Raji	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	-0.012710310116706536	[312]	[71]	0	hSpCas9	negative selection	395000
77989623	77989646	X	+	26472758	K562	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.48107771807594313	[229]	[270]	4	hSpCas9	negative selection	586109
77989915	77989938	X	+	26472758	K562	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	-0.5331888509971053	[299]	[174]	-3	hSpCas9	negative selection	586110
77998566	77998589	X	+	26472758	K562	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	0.14488305411553215	[44]	[41]	1	hSpCas9	negative selection	586111
78011527	78011550	X	-	26472758	K562	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	-0.3943532349441222	[477]	[306]	-3	hSpCas9	negative selection	586112
78012967	78012990	X	-	26472758	K562	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.06082888230309269	[1020]	[898]	0	hSpCas9	negative selection	586113
78013091	78013114	X	+	26472758	K562	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.2641369622809523	[217]	[220]	2	hSpCas9	negative selection	586114
78033604	78033627	X	+	26472758	K562	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	0.08014344828979111	[445]	[397]	0	hSpCas9	negative selection	586115
78042656	78042679	X	+	26472758	K562	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	0.48360639154587304	[60]	[71]	4	hSpCas9	negative selection	586116
78045482	78045505	X	-	26472758	K562	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	-0.7637552037792534	[176]	[87]	-4	hSpCas9	negative selection	586117
77988359	77988382	X	-	26472758	K562	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.6262067225952966	[405]	[528]	5	hSpCas9	negative selection	586118
77971703	77971726	X	-	26627737	DLD1	viability	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.2636142249560367	[1560]	[587,616,557]	2	hSpCas9	negative selection	846555
77988605	77988628	X	+	26627737	DLD1	viability	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	1.4975953435868914	[164]	[123,127,178]	9	hSpCas9	negative selection	846556
77989622	77989645	X	+	26627737	DLD1	viability	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	0.9007684482541594	[285]	[175,108,206]	8	hSpCas9	negative selection	846557
77998563	77998586	X	+	26627737	DLD1	viability	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.7525466473172188	[306]	[160,161,161]	7	hSpCas9	negative selection	846558
78009181	78009204	X	-	26627737	DLD1	viability	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.6306667725004393	[519]	[257,269,230]	6	hSpCas9	negative selection	846559
78013072	78013095	X	+	26627737	DLD1	viability	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.3475853058305064	[321]	[46,107,82]	-4	hSpCas9	negative selection	846560
77971703	77971726	X	-	26627737	GBM cells	viability after 5 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.016378549626256733	[836]	[548,358]	0	hSpCas9	negative selection	928870
77988605	77988628	X	+	26627737	GBM cells	viability after 5 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	0.3471877036384612	[117]	[68,91]	5	hSpCas9	negative selection	928871
77989622	77989645	X	+	26627737	GBM cells	viability after 5 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	1.109901532949884	[126]	[113,179]	9	hSpCas9	negative selection	928872
77998563	77998586	X	+	26627737	GBM cells	viability after 5 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.1117333693138226	[135]	[63,70]	-2	hSpCas9	negative selection	928873
78009181	78009204	X	-	26627737	GBM cells	viability after 5 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.2991976074745024	[171]	[77,148]	4	hSpCas9	negative selection	928874
78013072	78013095	X	+	26627737	GBM cells	viability after 5 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.6997235627325473	[105]	[44,24]	-8	hSpCas9	negative selection	928875
77971703	77971726	X	-	26627737	GBM cells	viability after 13 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.1316786361056359	[836]	[689,340]	1	hSpCas9	negative selection	1011185
77988605	77988628	X	+	26627737	GBM cells	viability after 13 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	0.16791098230405632	[117]	[61,79]	2	hSpCas9	negative selection	1011186
77989622	77989645	X	+	26627737	GBM cells	viability after 13 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	1.1080946868612633	[126]	[115,174]	9	hSpCas9	negative selection	1011187
77998563	77998586	X	+	26627737	GBM cells	viability after 13 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.37805494547474805	[135]	[96,94]	5	hSpCas9	negative selection	1011188
78009181	78009204	X	-	26627737	GBM cells	viability after 13 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.7840512852990411	[171]	[179,144]	8	hSpCas9	negative selection	1011189
78013072	78013095	X	+	26627737	GBM cells	viability after 13 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.5088514081973299	[105]	[51,30]	-6	hSpCas9	negative selection	1011190
77971703	77971726	X	-	26627737	GBM cells	viability after 21 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-0.2263784559614035	[836]	[395,381]	-2	hSpCas9	negative selection	1093500
77988605	77988628	X	+	26627737	GBM cells	viability after 21 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	0.2238418670458997	[117]	[77,71]	2	hSpCas9	negative selection	1093501
77989622	77989645	X	+	26627737	GBM cells	viability after 21 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	1.3214434934387291	[126]	[173,170]	9	hSpCas9	negative selection	1093502
77998563	77998586	X	+	26627737	GBM cells	viability after 21 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.037527195496597665	[135]	[83,60]	0	hSpCas9	negative selection	1093503
78009181	78009204	X	-	26627737	GBM cells	viability after 21 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.5972667169014763	[171]	[167,116]	6	hSpCas9	negative selection	1093504
78013072	78013095	X	+	26627737	GBM cells	viability after 21 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	0.08593793636811231	[105]	[69,52]	0	hSpCas9	negative selection	1093505
77971703	77971726	X	-	26627737	RPE1	viability after 9 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.6414061110977642	[1631]	[813,774]	4	hSpCas9	negative selection	1175815
77988605	77988628	X	+	26627737	RPE1	viability after 9 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	0.2534029513688853	[501]	[199,170]	1	hSpCas9	negative selection	1175816
77989622	77989645	X	+	26627737	RPE1	viability after 9 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	0.8994174265405919	[328]	[223,150]	6	hSpCas9	negative selection	1175817
77998563	77998586	X	+	26627737	RPE1	viability after 9 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	1.3171327597220805	[300]	[198,280]	7	hSpCas9	negative selection	1175818
78009181	78009204	X	-	26627737	RPE1	viability after 9 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	-0.8296632673787115	[516]	[94,85]	-5	hSpCas9	negative selection	1175819
78013072	78013095	X	+	26627737	RPE1	viability after 9 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.6858277319819345	[411]	[77,82]	-5	hSpCas9	negative selection	1175820
77971703	77971726	X	-	26627737	RPE1	viability after 12 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.8467836993095694	[1631]	[892,677]	5	hSpCas9	negative selection	1258130
77988605	77988628	X	+	26627737	RPE1	viability after 12 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	0.14539528412532704	[501]	[86,214]	1	hSpCas9	negative selection	1258131
77989622	77989645	X	+	26627737	RPE1	viability after 12 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	1.5601772227448838	[328]	[350,164]	8	hSpCas9	negative selection	1258132
77998563	77998586	X	+	26627737	RPE1	viability after 12 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.9388820502503354	[300]	[172,135]	6	hSpCas9	negative selection	1258133
78009181	78009204	X	-	26627737	RPE1	viability after 12 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	-2.0735149392833434	[516]	[32,32]	-8	hSpCas9	negative selection	1258134
78013072	78013095	X	+	26627737	RPE1	viability after 12 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.15770543707295548	[411]	[72,126]	-1	hSpCas9	negative selection	1258135
77971703	77971726	X	-	26627737	RPE1	viability after 15 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.5200602432416888	[1631]	[716,608]	3	hSpCas9	negative selection	1340445
77988605	77988628	X	+	26627737	RPE1	viability after 15 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.005667081583282441	[501]	[59,219]	0	hSpCas9	negative selection	1340446
77989622	77989645	X	+	26627737	RPE1	viability after 15 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	1.2781776135195129	[328]	[325,128]	7	hSpCas9	negative selection	1340447
77998563	77998586	X	+	26627737	RPE1	viability after 15 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.8365934554225233	[300]	[176,127]	5	hSpCas9	negative selection	1340448
78009181	78009204	X	-	26627737	RPE1	viability after 15 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	-1.4993839547386556	[516]	[66,36]	-7	hSpCas9	negative selection	1340449
78013072	78013095	X	+	26627737	RPE1	viability after 15 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	0.3246480738282158	[411]	[63,224]	2	hSpCas9	negative selection	1340450
77971703	77971726	X	-	26627737	RPE1	viability after 18 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	1.1837312849331851	[1631]	[1072,922]	6	hSpCas9	negative selection	1422760
77988605	77988628	X	+	26627737	RPE1	viability after 18 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.375858097201187	[501]	[86,122]	-2	hSpCas9	negative selection	1422761
77989622	77989645	X	+	26627737	RPE1	viability after 18 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	2.018684643606774	[328]	[498,210]	8	hSpCas9	negative selection	1422762
77998563	77998586	X	+	26627737	RPE1	viability after 18 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	1.1373028311931312	[300]	[183,172]	6	hSpCas9	negative selection	1422763
78009181	78009204	X	-	26627737	RPE1	viability after 18 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	-1.7383978293131572	[516]	[50,31]	-8	hSpCas9	negative selection	1422764
78013072	78013095	X	+	26627737	RPE1	viability after 18 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.7088667621425494	[411]	[24,113]	-4	hSpCas9	negative selection	1422765
77971703	77971726	X	-	26627737	HeLa	viability after 8 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-0.04797795420592754	[1491]	[670,691,536]	0	hSpCas9	negative selection	1505075
77988605	77988628	X	+	26627737	HeLa	viability after 8 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	0.7189844808651011	[99]	[58,5,141]	6	hSpCas9	negative selection	1505076
77989622	77989645	X	+	26627737	HeLa	viability after 8 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	-0.5786863990243287	[403]	[91,204,54]	-5	hSpCas9	negative selection	1505077
77998563	77998586	X	+	26627737	HeLa	viability after 8 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.5503789517109838	[234]	[85,210,138]	5	hSpCas9	negative selection	1505078
78009181	78009204	X	-	26627737	HeLa	viability after 8 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.2942327126662927	[286]	[137,148,167]	2	hSpCas9	negative selection	1505079
78013072	78013095	X	+	26627737	HeLa	viability after 8 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.7924672262589672	[192]	[58,13,72]	-7	hSpCas9	negative selection	1505080
77971703	77971726	X	-	26627737	HeLa	viability after 12 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-0.17870487703875293	[1491]	[703,288,672]	-1	hSpCas9	negative selection	1587390
77988605	77988628	X	+	26627737	HeLa	viability after 12 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	1.2593559763713371	[99]	[26,114,150]	8	hSpCas9	negative selection	1587391
77989622	77989645	X	+	26627737	HeLa	viability after 12 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	-0.4436448323060021	[403]	[271,71,33]	-4	hSpCas9	negative selection	1587392
77998563	77998586	X	+	26627737	HeLa	viability after 12 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.24071348178580998	[234]	[92,33,124]	-2	hSpCas9	negative selection	1587393
78009181	78009204	X	-	26627737	HeLa	viability after 12 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.5641228027469077	[286]	[61,144,318]	5	hSpCas9	negative selection	1587394
78013072	78013095	X	+	26627737	HeLa	viability after 12 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-1.2986566816784069	[192]	[40,8,49]	-8	hSpCas9	negative selection	1587395
77971703	77971726	X	-	26627737	HeLa	viability after 15 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-0.11797069804884508	[1491]	[692,501,475]	-1	hSpCas9	negative selection	1669705
77988605	77988628	X	+	26627737	HeLa	viability after 15 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	1.5700161261794852	[99]	[85,156,119]	9	hSpCas9	negative selection	1669706
77989622	77989645	X	+	26627737	HeLa	viability after 15 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	-1.1983747423118973	[403]	[37,86,91]	-8	hSpCas9	negative selection	1669707
77998563	77998586	X	+	26627737	HeLa	viability after 15 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.16377927879825815	[234]	[73,64,119]	-1	hSpCas9	negative selection	1669708
78009181	78009204	X	-	26627737	HeLa	viability after 15 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.7128864026934987	[286]	[74,176,334]	5	hSpCas9	negative selection	1669709
78013072	78013095	X	+	26627737	HeLa	viability after 15 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.7238492477439855	[192]	[62,1,79]	-6	hSpCas9	negative selection	1669710
77971703	77971726	X	-	26627737	HeLa	viability after 18 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-0.10204555984637431	[1491]	[459,436,475]	-1	hSpCas9	negative selection	1752020
77988605	77988628	X	+	26627737	HeLa	viability after 18 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	1.5730611790624884	[99]	[54,133,119]	8	hSpCas9	negative selection	1752021
77989622	77989645	X	+	26627737	HeLa	viability after 18 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	-1.1934917236623506	[403]	[21,76,91]	-8	hSpCas9	negative selection	1752022
77998563	77998586	X	+	26627737	HeLa	viability after 18 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.14230595389783707	[234]	[51,53,119]	-1	hSpCas9	negative selection	1752023
78009181	78009204	X	-	26627737	HeLa	viability after 18 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.7329969200474036	[286]	[51,150,334]	6	hSpCas9	negative selection	1752024
78013072	78013095	X	+	26627737	HeLa	viability after 18 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.7521219772568422	[192]	[40,0,79]	-6	hSpCas9	negative selection	1752025
77971703	77971726	X	-	26627737	HCT116	viability after 6 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-1.4278873792662725	[3470]	[274,162]	-7	hSpCas9	negative selection	1834335
77988605	77988628	X	+	26627737	HCT116	viability after 6 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	1.3749030965291242	[245]	[40,132]	7	hSpCas9	negative selection	1834336
77989622	77989645	X	+	26627737	HCT116	viability after 6 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	1.465892796635662	[662]	[265,299]	7	hSpCas9	negative selection	1834337
77998563	77998586	X	+	26627737	HCT116	viability after 6 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.6683133858243548	[289]	[38,22]	-4	hSpCas9	negative selection	1834338
78009181	78009204	X	-	26627737	HCT116	viability after 6 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.317084963476854	[412]	[96,71]	1	hSpCas9	negative selection	1834339
78013072	78013095	X	+	26627737	HCT116	viability after 6 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	1.6975079010666405	[185]	[128,75]	8	hSpCas9	negative selection	1834340
77971703	77971726	X	-	26627737	HCT116	viability after 8 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.004856809669842477	[975]	[608,546,464]	0	hSpCas9	negative selection	1916650
77988605	77988628	X	+	26627737	HCT116	viability after 8 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.922101454051808	[357]	[88,114,107]	-8	hSpCas9	negative selection	1916651
77989622	77989645	X	+	26627737	HCT116	viability after 8 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	0.46047408426676695	[225]	[174,156,181]	5	hSpCas9	negative selection	1916652
77998563	77998586	X	+	26627737	HCT116	viability after 8 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.05895615869076598	[183]	[66,129,118]	0	hSpCas9	negative selection	1916653
78009181	78009204	X	-	26627737	HCT116	viability after 8 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	-0.13312886663636492	[178]	[82,121,64]	-1	hSpCas9	negative selection	1916654
78013072	78013095	X	+	26627737	HCT116	viability after 8 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.6243852787982782	[175]	[68,69,49]	-6	hSpCas9	negative selection	1916655
77971703	77971726	X	-	26627737	HCT116	viability after 9 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-0.8556128465025645	[3470]	[786,294]	-6	hSpCas9	negative selection	1998965
77988605	77988628	X	+	26627737	HCT116	viability after 9 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	1.0064755154614595	[245]	[117,142]	7	hSpCas9	negative selection	1998966
77989622	77989645	X	+	26627737	HCT116	viability after 9 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	-0.02373709801062722	[662]	[229,129]	0	hSpCas9	negative selection	1998967
77998563	77998586	X	+	26627737	HCT116	viability after 9 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.027215308861351595	[289]	[136,32]	0	hSpCas9	negative selection	1998968
78009181	78009204	X	-	26627737	HCT116	viability after 9 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	1.42075207307036	[412]	[373,232]	8	hSpCas9	negative selection	1998969
78013072	78013095	X	+	26627737	HCT116	viability after 9 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	1.6398575499211572	[185]	[51,235]	8	hSpCas9	negative selection	1998970
77971703	77971726	X	-	26627737	HCT116	viability after 12 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.14291769923723985	[975]	[567,531,597]	1	hSpCas9	negative selection	2081280
77988605	77988628	X	+	26627737	HCT116	viability after 12 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.8266787220966694	[357]	[95,59,161]	-7	hSpCas9	negative selection	2081281
77989622	77989645	X	+	26627737	HCT116	viability after 12 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	0.3568605360392769	[225]	[85,188,187]	3	hSpCas9	negative selection	2081282
77998563	77998586	X	+	26627737	HCT116	viability after 12 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.042780788974379425	[183]	[110,106,79]	0	hSpCas9	negative selection	2081283
78009181	78009204	X	-	26627737	HCT116	viability after 12 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.7831155571503072	[178]	[160,214,110]	7	hSpCas9	negative selection	2081284
78013072	78013095	X	+	26627737	HCT116	viability after 12 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.5753108420521025	[175]	[25,86,76]	-6	hSpCas9	negative selection	2081285
77971703	77971726	X	-	26627737	HCT116	viability after 15 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-0.04600796478467939	[975]	[719,444,485]	0	hSpCas9	negative selection	2163595
77988605	77988628	X	+	26627737	HCT116	viability after 15 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.6088043617241388	[357]	[133,105,163]	-6	hSpCas9	negative selection	2163596
77989622	77989645	X	+	26627737	HCT116	viability after 15 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	0.37286003989311206	[225]	[221,139,148]	3	hSpCas9	negative selection	2163597
77998563	77998586	X	+	26627737	HCT116	viability after 15 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.22051146510291447	[183]	[63,160,136]	2	hSpCas9	negative selection	2163598
78009181	78009204	X	-	26627737	HCT116	viability after 15 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.4227595333223526	[178]	[172,132,111]	4	hSpCas9	negative selection	2163599
78013072	78013095	X	+	26627737	HCT116	viability after 15 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.6947974820412457	[175]	[28,69,83]	-6	hSpCas9	negative selection	2163600
77971703	77971726	X	-	26627737	HCT116	viability after 18 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.39641341938808994	[975]	[544,730,577]	3	hSpCas9	negative selection	2245910
77988605	77988628	X	+	26627737	HCT116	viability after 18 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.776811617605534	[357]	[97,76,130]	-6	hSpCas9	negative selection	2245911
77989622	77989645	X	+	26627737	HCT116	viability after 18 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	0.5137950627863556	[225]	[88,174,204]	4	hSpCas9	negative selection	2245912
77998563	77998586	X	+	26627737	HCT116	viability after 18 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.5588900402937081	[183]	[112,130,149]	5	hSpCas9	negative selection	2245913
78009181	78009204	X	-	26627737	HCT116	viability after 18 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.8596321199766659	[178]	[119,172,177]	6	hSpCas9	negative selection	2245914
78013072	78013095	X	+	26627737	HCT116	viability after 18 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.1808206456136504	[175]	[88,70,64]	-2	hSpCas9	negative selection	2245915
77969801	77969824	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAATCATCATAGTCAAACACCGG	ATP7A	ENSG00000165240	-0.38899196129608316	[97,159]	[20,21]	-2	dCas9-VP64	positive selection	2390648
77969757	77969780	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATATATCCCATGGAAACAGTGG	ATP7A	ENSG00000165240	-0.3162355312866263	[23,308]	[5,54]	-1	dCas9-VP64	positive selection	2390649
77969748	77969771	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CATGGAAACAGTGGTTCCTCTGG	ATP7A	ENSG00000165240	0.8370113003063029	[130,67]	[26,50]	3	dCas9-VP64	positive selection	2390650
78010602	78010625	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAGTCTCACTCTGTCGCCTGG	ATP7A	ENSG00000165240	3.8475142164822467	[640,932]	[1963,3090]	9	dCas9-VP64	positive selection	2395803
77915793	77915816	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGCCTCCAGG	ATP7A	ENSG00000165240	-2.007733074360467	[162,472]	[3,30]	-9	dCas9-VP64	positive selection	2424007
78012546	78012569	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGTTTGAGACCAGCCTGGG	ATP7A	ENSG00000165240	-1.6026008362934678	[306,558]	[26,34]	-8	dCas9-VP64	positive selection	2428498
77920306	77920329	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATGGCATGAACCCGAG	ATP7A	ENSG00000165240	-0.6383309141464126	[28,8]	[1,1]	-3	dCas9-VP64	positive selection	2452414
77972390	77972413	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCCCAGGCTGGAGTGCAGTGG	ATP7A	ENSG00000165240	1.5196799666234522	[9,52]	[2,38]	5	dCas9-VP64	positive selection	2457375
77969801	77969824	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAATCATCATAGTCAAACACCGG	ATP7A	ENSG00000165240	0.9007183019005989	[157,520]	[170,236]	6	dCas9-VP64	positive selection	2485903
77969757	77969780	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATATATCCCATGGAAACAGTGG	ATP7A	ENSG00000165240	-0.34457139202868303	[64,76]	[12,21]	-3	dCas9-VP64	positive selection	2485904
77969748	77969771	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CATGGAAACAGTGGTTCCTCTGG	ATP7A	ENSG00000165240	-0.9052190870424406	[92,185]	[14,31]	-8	dCas9-VP64	positive selection	2485905
78010602	78010625	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAGTCTCACTCTGTCGCCTGG	ATP7A	ENSG00000165240	0.025453313513389197	[295,394]	[83,142]	0	dCas9-VP64	positive selection	2491058
77915793	77915816	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGCCTCCAGG	ATP7A	ENSG00000165240	2.233334387673139	[58,128]	[217,75]	8	dCas9-VP64	positive selection	2519262
78012546	78012569	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGTTTGAGACCAGCCTGGG	ATP7A	ENSG00000165240	0.9241793657004961	[25,55]	[22,26]	6	dCas9-VP64	positive selection	2523753
77920306	77920329	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATGGCATGAACCCGAG	ATP7A	ENSG00000165240	4.9253728466972815	[108,193]	[3088,18]	9	dCas9-VP64	positive selection	2547669
77972390	77972413	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCCCAGGCTGGAGTGCAGTGG	ATP7A	ENSG00000165240	-0.8181473823206423	[116,171]	[31,20]	-7	dCas9-VP64	positive selection	2552630
78009146	78009169	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTAGTCTCACAAAACACAGAGGG	ATP7A	ENSG00000165240	0.2135427982668965	[4,4]	[3,4]	4	hSpCas9	positive selection	2972538
77988511	77988534	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTGGCATTCACTATAGAAGGG	ATP7A	ENSG00000165240	-0.11208402359946362	[5,4]	[4,2]	-1	hSpCas9	positive selection	2972539
77989572	77989595	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTGCATTATACTTCACAATGG	ATP7A	ENSG00000165240	0.1931432072159543	[4,4]	[4,4]	4	hSpCas9	positive selection	2972540
77989889	77989912	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTTCTGGAGAGGTTAGTAGAGG	ATP7A	ENSG00000165240	0.01816922361689849	[4,4]	[3,3]	0	hSpCas9	positive selection	2972541
78009146	78009169	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTAGTCTCACAAAACACAGAGGG	ATP7A	ENSG00000165240	0.30641671180011953	[4,4]	[2,4]	5	hSpCas9	positive selection	3040396
77988511	77988534	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTGGCATTCACTATAGAAGGG	ATP7A	ENSG00000165240	-0.23391200232430379	[5,5]	[3,2]	-3	hSpCas9	positive selection	3040397
77989572	77989595	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTGCATTATACTTCACAATGG	ATP7A	ENSG00000165240	0.0217192840169399	[4,4]	[5,1]	0	hSpCas9	positive selection	3040398
77989889	77989912	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTTCTGGAGAGGTTAGTAGAGG	ATP7A	ENSG00000165240	0.3531670793397071	[4,4]	[3,4]	6	hSpCas9	positive selection	3040399
78046304	78046327		-	24336571	A375	resistance to PLX after 7 days	AGTTCATAACTCTCGTAAGTTGG	ATP7A	ENSG00000165240	-0.2805803974172496	[8,7]	[7,5]	-8	hSpCas9	positive selection	3138761
77988710	77988733		+	24336571	A375	resistance to PLX after 7 days	CAAGGTGTTCAGCGAATTAAAGG	ATP7A	ENSG00000165240	0.013724422422497606	[14,14]	[12,15]	0	hSpCas9	positive selection	3138772
77988381	77988404		-	24336571	A375	resistance to PLX after 7 days	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.13726320682149845	[9,9]	[8,8]	-4	hSpCas9	positive selection	3138783
78046361	78046384		+	24336571	A375	resistance to PLX after 7 days	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.2914074158505259	[25,27]	[18,24]	-8	hSpCas9	positive selection	3138794
78046304	78046327		-	24336571	A375	resistance to PLX after 14 days	AGTTCATAACTCTCGTAAGTTGG	ATP7A	ENSG00000165240	-0.7865803599995314	[9,8]	[1,1]	-8	hSpCas9	positive selection	3196554
77988710	77988733		+	24336571	A375	resistance to PLX after 14 days	CAAGGTGTTCAGCGAATTAAAGG	ATP7A	ENSG00000165240	0.860007973975735	[14,9]	[10,10]	7	hSpCas9	positive selection	3196565
77988381	77988404		-	24336571	A375	resistance to PLX after 14 days	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.13837577016047503	[10,5]	[3,3]	1	hSpCas9	positive selection	3196576
78046361	78046384		+	24336571	A375	resistance to PLX after 14 days	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.5167599940098075	[23,21]	[7,5]	-6	hSpCas9	positive selection	3196587
78046304	78046327		-	24336571	A375	viability after 7 days	AGTTCATAACTCTCGTAAGTTGG	ATP7A	ENSG00000165240	-0.08721352499324825	[9]	[8,7]	-1	hSpCas9	negative selection	3254347
77988710	77988733		+	24336571	A375	viability after 7 days	CAAGGTGTTCAGCGAATTAAAGG	ATP7A	ENSG00000165240	0.4748477311843411	[10]	[14,14]	7	hSpCas9	negative selection	3254358
77988381	77988404		-	24336571	A375	viability after 7 days	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.16638424980361324	[11]	[9,9]	-2	hSpCas9	negative selection	3254369
78046361	78046384		+	24336571	A375	viability after 7 days	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.09440227039811622	[29]	[25,27]	-1	hSpCas9	negative selection	3254380
78046304	78046327		-	24336571	A375	viability after 14 days	AGTTCATAACTCTCGTAAGTTGG	ATP7A	ENSG00000165240	0.053284310000668356	[9]	[9,8]	0	hSpCas9	negative selection	3312140
77988710	77988733		+	24336571	A375	viability after 14 days	CAAGGTGTTCAGCGAATTAAAGG	ATP7A	ENSG00000165240	0.28016467991342886	[10]	[14,9]	3	hSpCas9	negative selection	3312151
77988381	77988404		-	24336571	A375	viability after 14 days	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.398491433845923	[11]	[10,5]	-5	hSpCas9	negative selection	3312162
78046361	78046384		+	24336571	A375	viability after 14 days	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.3079768743730922	[29]	[23,21]	-4	hSpCas9	negative selection	3312173
77989904	77989927	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	1.848046213448131	[41,42]	[0,0]	7	hSpCas9	positive selection	3338201
77989640	77989663	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	1.938702179931707	[25,53]	[0,0]	7	hSpCas9	positive selection	3338202
77988381	77988404	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.24074732278438032	[146,214]	[0,0]	-1	hSpCas9	positive selection	3338203
77998643	77998666	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.18561728440289318	[173,173]	[0,0]	-1	hSpCas9	positive selection	3357458
77998473	77998496	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.47738340878000324	[212,212]	[0,0]	-3	hSpCas9	positive selection	3357459
78046361	78046384	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.12637808102821713	[166,166]	[0,0]	0	hSpCas9	positive selection	3357460
78009145	78009168	X	+	26780180	HT29	viability (Avana library 4 designs)	CTAGTCTCACAAAACACAGAGGG	ATP7A	ENSG00000165240	0.807316321874699	[]	[]	3	hSpCas9	negative selection	3408689
77988511	77988534	X	-	26780180	HT29	viability (Avana library 4 designs)	GATTGGCATTCACTATAGAAGGG	ATP7A	ENSG00000165240	0.052101907761377	[]	[]	0	hSpCas9	negative selection	3408690
77989572	77989595	X	-	26780180	HT29	viability (Avana library 4 designs)	GCTTGCATTATACTTCACAATGG	ATP7A	ENSG00000165240	0.287415808446071	[]	[]	1	hSpCas9	negative selection	3408691
77989889	77989912	X	-	26780180	HT29	viability (Avana library 4 designs)	GTTTCTGGAGAGGTTAGTAGAGG	ATP7A	ENSG00000165240	0.593371172292821	[]	[]	2	hSpCas9	negative selection	3408692
77989572	77989595	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTGCATTATACTTCACAATGG	ATP7A	ENSG00000165240	-10.0385210333065	[]	[]	-7	hSpCas9	negative selection	3482351
77988511	77988534	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATTGGCATTCACTATAGAAGGG	ATP7A	ENSG00000165240	-2.95507636257438	[]	[]	-4	hSpCas9	negative selection	3482352
78009145	78009168	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGTCTCACAAAACACAGAGGG	ATP7A	ENSG00000165240	-5.8658769203986	[]	[]	-6	hSpCas9	negative selection	3482353
77989889	77989912	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTCTGGAGAGGTTAGTAGAGG	ATP7A	ENSG00000165240	1.03733405373879	[]	[]	1	hSpCas9	negative selection	3482354
77988631	77988654	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTCGTGCTGAAGATGAAAGTGG	ATP7A	ENSG00000165240	1.12954851724682	[]	[]	1	hSpCas9	negative selection	3482355
77989395	77989418	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CACCAGTTAAATCCTCAGAAGGG	ATP7A	ENSG00000165240	-2.6913896711316	[]	[]	-3	hSpCas9	negative selection	3482356
77989572	77989595	X	-	26780180	A375	viability (Avana lentiGuide)	GCTTGCATTATACTTCACAATGG	ATP7A	ENSG00000165240	0.89004667002839	[]	[]	1	hSpCas9	negative selection	3591010
77988511	77988534	X	-	26780180	A375	viability (Avana lentiGuide)	GATTGGCATTCACTATAGAAGGG	ATP7A	ENSG00000165240	-3.5979133697284	[]	[]	-6	hSpCas9	negative selection	3591011
78009145	78009168	X	+	26780180	A375	viability (Avana lentiGuide)	CTAGTCTCACAAAACACAGAGGG	ATP7A	ENSG00000165240	6.07402433062357	[]	[]	5	hSpCas9	negative selection	3591012
77989889	77989912	X	-	26780180	A375	viability (Avana lentiGuide)	GTTTCTGGAGAGGTTAGTAGAGG	ATP7A	ENSG00000165240	0.637384066963301	[]	[]	0	hSpCas9	negative selection	3591013
77988631	77988654	X	+	26780180	A375	viability (Avana lentiGuide)	AGTCGTGCTGAAGATGAAAGTGG	ATP7A	ENSG00000165240	-3.45458056338559	[]	[]	-6	hSpCas9	negative selection	3591014
77989395	77989418	X	+	26780180	A375	viability (Avana lentiGuide)	CACCAGTTAAATCCTCAGAAGGG	ATP7A	ENSG00000165240	-1.25605867240647	[]	[]	-2	hSpCas9	negative selection	3591015
77989572	77989595	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTGCATTATACTTCACAATGG	ATP7A	ENSG00000165240	-0.788021714662524	[6]	[3,2]	-8	hSpCas9	positive selection	3699669
77988511	77988534	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTGGCATTCACTATAGAAGGG	ATP7A	ENSG00000165240	-0.18069329082686203	[7]	[6,6]	-3	hSpCas9	positive selection	3699670
78009145	78009168	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGTCTCACAAAACACAGAGGG	ATP7A	ENSG00000165240	-0.5211062892718792	[5]	[4,2]	-6	hSpCas9	positive selection	3699671
77989889	77989912	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTCTGGAGAGGTTAGTAGAGG	ATP7A	ENSG00000165240	0.10857076373209307	[5]	[5,6]	3	hSpCas9	positive selection	3699672
77988631	77988654	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTCGTGCTGAAGATGAAAGTGG	ATP7A	ENSG00000165240	0.23301227885814382	[4]	[5,5]	6	hSpCas9	positive selection	3699673
77989395	77989418	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACCAGTTAAATCCTCAGAAGGG	ATP7A	ENSG00000165240	-0.7804715244300011	[5]	[2,1]	-8	hSpCas9	positive selection	3699674
77989572	77989595	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTGCATTATACTTCACAATGG	ATP7A	ENSG00000165240	0.3835738916740934	[6]	[7,7]	9	hSpCas9	positive selection	3808276
77988511	77988534	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTGGCATTCACTATAGAAGGG	ATP7A	ENSG00000165240	0.2593052032355264	[6]	[7,5]	7	hSpCas9	positive selection	3808277
78009145	78009168	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGTCTCACAAAACACAGAGGG	ATP7A	ENSG00000165240	0.10355045422802066	[5]	[5,4]	2	hSpCas9	positive selection	3808278
77989889	77989912	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTCTGGAGAGGTTAGTAGAGG	ATP7A	ENSG00000165240	0.35706756858063116	[6]	[6,6]	9	hSpCas9	positive selection	3808279
77988631	77988654	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTCGTGCTGAAGATGAAAGTGG	ATP7A	ENSG00000165240	-0.011989093847256792	[5]	[4,4]	0	hSpCas9	positive selection	3808280
77989395	77989418	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACCAGTTAAATCCTCAGAAGGG	ATP7A	ENSG00000165240	0.02213649615239152	[4]	[4,2]	0	hSpCas9	positive selection	3808281
77998473	77998496	X	+	26780180	A375	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	1.60426086518687	[]	[]	8	hSpCas9	negative selection	3916525
77989640	77989663	X	-	26780180	A375	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.995186703733735	[]	[]	4	hSpCas9	negative selection	3916526
77989904	77989927	X	-	26780180	A375	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	1.18230202451019	[]	[]	6	hSpCas9	negative selection	3916527
77998643	77998666	X	-	26780180	A375	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	1.1738403597024	[]	[]	6	hSpCas9	negative selection	3916528
77988381	77988404	X	-	26780180	A375	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.439898173901892	[]	[]	1	hSpCas9	negative selection	3916529
78046361	78046384	X	+	26780180	A375	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	0.729422374233973	[]	[]	2	hSpCas9	negative selection	3916530
77998473	77998496	X	+	26780180	HT29	viability (GeCKOv2 library)	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	2.07718471073708	[]	[]	9	hSpCas9	negative selection	4024491
77989640	77989663	X	-	26780180	HT29	viability (GeCKOv2 library)	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	1.47127755913007	[]	[]	7	hSpCas9	negative selection	4024492
77989904	77989927	X	-	26780180	HT29	viability (GeCKOv2 library)	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	1.41793681590457	[]	[]	7	hSpCas9	negative selection	4024493
77998643	77998666	X	-	26780180	HT29	viability (GeCKOv2 library)	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	1.60724333533748	[]	[]	8	hSpCas9	negative selection	4024494
77988381	77988404	X	-	26780180	HT29	viability (GeCKOv2 library)	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.483547795938284	[]	[]	1	hSpCas9	negative selection	4024495
78046361	78046384	X	+	26780180	HT29	viability (GeCKOv2 library)	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	0.855861754285624	[]	[]	3	hSpCas9	negative selection	4024496
78046304	78046327	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTTCATAACTCTCGTAAGTTGG	ATP7A	ENSG00000165240	-0.22722558843543061	[2]	[1,0]	-5	hSpCas9	positive selection	4164042
77988710	77988733	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAGGTGTTCAGCGAATTAAAGG	ATP7A	ENSG00000165240	0.15922092325255668	[3]	[1,3]	4	hSpCas9	positive selection	4164053
77988381	77988404	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.1732320577724853	[3]	[1,1]	-4	hSpCas9	positive selection	4164064
78046361	78046384	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.15337394656568482	[4]	[2,2]	-4	hSpCas9	positive selection	4164075
78046304	78046327	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTTCATAACTCTCGTAAGTTGG	ATP7A	ENSG00000165240	-0.5170085956826926	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4228064
77988710	77988733	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAGGTGTTCAGCGAATTAAAGG	ATP7A	ENSG00000165240	1.5378136002114187	[2]	[2,2,4,3]	9	hSpCas9	positive selection	4228075
77988381	77988404	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.017379118525021074	[3]	[3,1,1,0]	0	hSpCas9	positive selection	4228086
78046361	78046384	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.15033154606082563	[4]	[3,3,0,0]	-2	hSpCas9	positive selection	4228097
77989904	77989927	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.04472616783541705	[2]	[2,0]	0	hSpCas9	positive selection	4257470
77989640	77989663	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.778006744945599	[1]	[0,4]	9	hSpCas9	positive selection	4257471
77988381	77988404	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.021385186072673867	[3]	[3,1]	0	hSpCas9	positive selection	4257472
77998643	77998666	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	0.08037894249640642	[3]	[3,2]	1	hSpCas9	positive selection	4321754
77998473	77998496	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.3110341743213806	[3]	[3,0]	-6	hSpCas9	positive selection	4321755
78046361	78046384	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	0.2918800212229481	[3]	[3,3]	6	hSpCas9	positive selection	4321756
77988663	77988685	X	-	27760321	OCIAML3	viability	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.17859626630882586	[693,659]	[414,537]	-2	hSpCas9	negative selection	4380725
77989829	77989851	X	-	27760321	OCIAML3	viability	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	0.40089471091236795	[185,179]	[207,164]	5	hSpCas9	negative selection	4380726
77998510	77998532	X	-	27760321	OCIAML3	viability	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.628442372055962	[688,531]	[651,837]	7	hSpCas9	negative selection	4380727
77998643	77998665	X	-	27760321	OCIAML3	viability	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.4272104605449101	[598,517]	[336,306]	-4	hSpCas9	negative selection	4380728
78009124	78009146	X	-	27760321	OCIAML3	viability	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	-1.2065910966237345	[178,191]	[54,73]	-8	hSpCas9	negative selection	4380729
77988663	77988685	X	-	27760321	OCIAML2	viability	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.48300460386668465	[693,659]	[302,509]	-5	hSpCas9	negative selection	4464188
77989829	77989851	X	-	27760321	OCIAML2	viability	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	-0.034216838544388395	[185,179]	[124,170]	0	hSpCas9	negative selection	4464189
77998510	77998532	X	-	27760321	OCIAML2	viability	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.17798370517249612	[688,531]	[479,652]	2	hSpCas9	negative selection	4464190
77998643	77998665	X	-	27760321	OCIAML2	viability	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.1164589118366586	[598,517]	[340,513]	-1	hSpCas9	negative selection	4464191
78009124	78009146	X	-	27760321	OCIAML2	viability	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	0.4149431601795125	[178,191]	[177,231]	5	hSpCas9	negative selection	4464192
77988663	77988685	X	-	27760321	MV411	viability	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-1.2469105460309964	[693,659]	[271,62]	-7	hSpCas9	negative selection	4547651
77989829	77989851	X	-	27760321	MV411	viability	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	-0.05404365508171183	[185,179]	[52,211]	0	hSpCas9	negative selection	4547652
77998510	77998532	X	-	27760321	MV411	viability	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.889627586544568	[688,531]	[461,1159]	6	hSpCas9	negative selection	4547653
77998643	77998665	X	-	27760321	MV411	viability	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	0.8612047154705939	[598,517]	[803,462]	6	hSpCas9	negative selection	4547654
78009124	78009146	X	-	27760321	MV411	viability	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	1.196637556956073	[178,191]	[404,97]	8	hSpCas9	negative selection	4547655
77988663	77988685	X	-	27760321	HL60	viability	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.26052523090350727	[693,659]	[336,594]	-3	hSpCas9	negative selection	4631114
77989829	77989851	X	-	27760321	HL60	viability	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	-0.37511903046687944	[185,179]	[114,115]	-4	hSpCas9	negative selection	4631115
77998510	77998532	X	-	27760321	HL60	viability	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.16176260284088456	[688,531]	[580,524]	2	hSpCas9	negative selection	4631116
77998643	77998665	X	-	27760321	HL60	viability	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.0035339344827784447	[598,517]	[350,562]	0	hSpCas9	negative selection	4631117
78009124	78009146	X	-	27760321	HL60	viability	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	0.1619908957565046	[178,191]	[106,237]	2	hSpCas9	negative selection	4631118
77988663	77988685	X	-	27760321	HT1080	viability	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.3873275147497818	[659,514]	[166,191]	-2	hSpCas9	negative selection	4714577
77989829	77989851	X	-	27760321	HT1080	viability	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	-0.003109058071518067	[179,140]	[80,44]	0	hSpCas9	negative selection	4714578
77998510	77998532	X	-	27760321	HT1080	viability	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.36128940178204294	[531,414]	[216,269]	1	hSpCas9	negative selection	4714579
77998643	77998665	X	-	27760321	HT1080	viability	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	0.6953004728167871	[517,403]	[209,392]	4	hSpCas9	negative selection	4714580
78009124	78009146	X	-	27760321	HT1080	viability	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	-2.451304800479096	[191,149]	[0,24]	-7	hSpCas9	negative selection	4714581
77988663	77988685	X	-	27760321	HT29	viability after 7 days	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.4678107940561154	[659,514]	[630,383,631]	-6	hSpCas9	negative selection	4798040
77989829	77989851	X	-	27760321	HT29	viability after 7 days	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	-1.6577759840406425	[179,140]	[42,85,63]	-9	hSpCas9	negative selection	4798041
77998510	77998532	X	-	27760321	HT29	viability after 7 days	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.355219087904211	[531,414]	[1015,641,712]	5	hSpCas9	negative selection	4798042
77998643	77998665	X	-	27760321	HT29	viability after 7 days	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	0.1091825768669708	[517,403]	[711,534,678]	1	hSpCas9	negative selection	4798043
78009124	78009146	X	-	27760321	HT29	viability after 7 days	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	-1.1444684822142956	[191,149]	[130,48,121]	-8	hSpCas9	negative selection	4798044
77988663	77988685	X	-	27760321	HT29	viability after 25 days	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.3944685593622587	[659,514]	[461,463,619]	-4	hSpCas9	negative selection	4881503
77989829	77989851	X	-	27760321	HT29	viability after 25 days	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	0.6378839833774157	[179,140]	[217,358,282]	7	hSpCas9	negative selection	4881504
77998510	77998532	X	-	27760321	HT29	viability after 25 days	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.20782519155092016	[531,414]	[694,415,773]	2	hSpCas9	negative selection	4881505
77998643	77998665	X	-	27760321	HT29	viability after 25 days	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.3089268791798187	[517,403]	[331,549,395]	-3	hSpCas9	negative selection	4881506
78009124	78009146	X	-	27760321	HT29	viability after 25 days	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	-0.38729954371786857	[191,149]	[190,99,154]	-4	hSpCas9	negative selection	4881507
77988663	77988685	X	-	27760321	HT29	viability after 22 days	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.5934292798578831	[659,514]	[545,328,472]	-5	hSpCas9	negative selection	4964966
77989829	77989851	X	-	27760321	HT29	viability after 22 days	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	0.5635702599710718	[179,140]	[226,230,366]	6	hSpCas9	negative selection	4964967
77998510	77998532	X	-	27760321	HT29	viability after 22 days	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.2722795752529932	[531,414]	[748,654,575]	3	hSpCas9	negative selection	4964968
77998643	77998665	X	-	27760321	HT29	viability after 22 days	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.24978015852185648	[517,403]	[260,496,592]	-3	hSpCas9	negative selection	4964969
78009124	78009146	X	-	27760321	HT29	viability after 22 days	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	-0.4104724563870583	[191,149]	[216,117,108]	-4	hSpCas9	negative selection	4964970
77988663	77988685	X	-	27760321	HT29	viability after 19 days	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.28397141673235377	[659,514]	[559,462,629]	-3	hSpCas9	negative selection	5048429
77989829	77989851	X	-	27760321	HT29	viability after 19 days	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	0.28301073148685485	[179,140]	[370,238,80]	2	hSpCas9	negative selection	5048430
77998510	77998532	X	-	27760321	HT29	viability after 19 days	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.05215619159876134	[531,414]	[529,329,810]	0	hSpCas9	negative selection	5048431
77998643	77998665	X	-	27760321	HT29	viability after 19 days	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	0.31511346347162716	[517,403]	[456,579,899]	3	hSpCas9	negative selection	5048432
78009124	78009146	X	-	27760321	HT29	viability after 19 days	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	0.4367501190216966	[191,149]	[387,370,55]	4	hSpCas9	negative selection	5048433
77988663	77988685	X	-	27760321	HT29	viability after 16 days	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.5601608311362497	[659,514]	[417,509,404]	-5	hSpCas9	negative selection	5131892
77989829	77989851	X	-	27760321	HT29	viability after 16 days	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	0.40593514987619794	[179,140]	[328,217,175]	4	hSpCas9	negative selection	5131893
77998510	77998532	X	-	27760321	HT29	viability after 16 days	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.1252601915701309	[531,414]	[458,502,761]	1	hSpCas9	negative selection	5131894
77998643	77998665	X	-	27760321	HT29	viability after 16 days	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.1673818095939099	[517,403]	[584,403,401]	-2	hSpCas9	negative selection	5131895
78009124	78009146	X	-	27760321	HT29	viability after 16 days	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	-0.43385629136710624	[191,149]	[220,117,93]	-4	hSpCas9	negative selection	5131896
77988663	77988685	X	-	27760321	HT29	viability after 13 days	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.41160519951442165	[659,514]	[774,377,390]	-5	hSpCas9	negative selection	5215355
77989829	77989851	X	-	27760321	HT29	viability after 13 days	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	0.960128075297392	[179,140]	[430,399,261]	9	hSpCas9	negative selection	5215356
77998510	77998532	X	-	27760321	HT29	viability after 13 days	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.22196378337970935	[531,414]	[463,659,788]	2	hSpCas9	negative selection	5215357
77998643	77998665	X	-	27760321	HT29	viability after 13 days	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.09898978622627103	[517,403]	[427,552,515]	-1	hSpCas9	negative selection	5215358
78009124	78009146	X	-	27760321	HT29	viability after 13 days	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	-0.3509651832594902	[191,149]	[244,109,113]	-4	hSpCas9	negative selection	5215359
77988663	77988685	X	-	27760321	HT29	viability after 10 days	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-0.7977235142401582	[659,514]	[273,511,480]	-7	hSpCas9	negative selection	5298818
77989829	77989851	X	-	27760321	HT29	viability after 10 days	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	-0.31440023325851074	[179,140]	[188,197,98]	-4	hSpCas9	negative selection	5298819
77998510	77998532	X	-	27760321	HT29	viability after 10 days	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	0.06690312900725515	[531,414]	[775,476,600]	0	hSpCas9	negative selection	5298820
77998643	77998665	X	-	27760321	HT29	viability after 10 days	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.36006225327363	[517,403]	[315,502,525]	-5	hSpCas9	negative selection	5298821
78009124	78009146	X	-	27760321	HT29	viability after 10 days	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	-0.7408805540228918	[191,149]	[76,84,217]	-7	hSpCas9	negative selection	5298822
77988663	77988685	X	-	27760321	MOLM13	viability	GTGCTAGTACATGAATGGCAGG	ATP7A	ENSG00000165240	-1.540340946852845	[693,659]	[198,73]	-7	hSpCas9	negative selection	5382281
77989829	77989851	X	-	27760321	MOLM13	viability	CTCGTATGGATTTTACACCTGG	ATP7A	ENSG00000165240	-0.9887017615128351	[185,179]	[83,24]	-5	hSpCas9	negative selection	5382282
77998510	77998532	X	-	27760321	MOLM13	viability	AAAGCGGCATTTCCGATGAAGG	ATP7A	ENSG00000165240	2.7565445580358565	[688,531]	[4721,257]	9	hSpCas9	negative selection	5382283
77998643	77998665	X	-	27760321	MOLM13	viability	CGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	0.9231753768614465	[598,517]	[495,680]	6	hSpCas9	negative selection	5382284
78009124	78009146	X	-	27760321	MOLM13	viability	GACTCTATTTTATGTACGCAGG	ATP7A	ENSG00000165240	-1.667961515092711	[178,191]	[37,28]	-7	hSpCas9	negative selection	5382285
77910916	77910939	X	+	27661255	K562	viability	GAGAAGGTCATGTTAGTCTGGGG	ATP7A	ENSG00000165240	0.1294120299490532	[833,1073]	[879,786]	4	dCas9-KRAB	negative selection	5464344
77910842	77910865	X	-	27661255	K562	viability	GGACGACGGGAAGCCAATGTAGG	ATP7A	ENSG00000165240	-0.046502613884750764	[758,836]	[735,513]	-2	dCas9-KRAB	negative selection	5464345
77989904	77989927	X	-	27260156	BXPC3	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.16488541926518152	[209]	[190,225,283,295]	3	hSpCas9	negative selection	5529930
77989640	77989663	X	-	27260156	BXPC3	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.2746559443317802	[166]	[112,170,110,187]	-6	hSpCas9	negative selection	5529931
77988381	77988404	X	-	27260156	BXPC3	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.9403385383817645	[629]	[282,372,343,379]	-9	hSpCas9	negative selection	5529932
77998643	77998666	X	-	27260156	BXPC3	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.38209648841353117	[706]	[505,500,620,659]	-7	hSpCas9	negative selection	5594214
77998473	77998496	X	+	27260156	BXPC3	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.39706183706997067	[737]	[542,568,504,746]	-7	hSpCas9	negative selection	5594215
78046361	78046384	X	+	27260156	BXPC3	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.17752669449984376	[687]	[467,696,620,786]	-4	hSpCas9	negative selection	5594216
77989904	77989927	X	-	27260156	A673	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	-0.06455250051528205	[209]	[248,272,192,249]	-2	hSpCas9	negative selection	5651181
77989640	77989663	X	-	27260156	A673	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.45973733891125823	[166]	[144,151,164,118]	-8	hSpCas9	negative selection	5651182
77988381	77988404	X	-	27260156	A673	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.5506396731169474	[629]	[645,536,415,478]	-8	hSpCas9	negative selection	5651183
77998643	77998666	X	-	27260156	A673	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.7034880918636959	[706]	[661,442,430,569]	-9	hSpCas9	negative selection	5715465
77998473	77998496	X	+	27260156	A673	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.5609801337146684	[737]	[607,585,572,637]	-8	hSpCas9	negative selection	5715466
78046361	78046384	X	+	27260156	A673	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.4581324579414654	[687]	[699,540,667,501]	-8	hSpCas9	negative selection	5715467
77989904	77989927	X	-	27260156	A375	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.9763637234553397	[209]	[495,425,555,446]	9	hSpCas9	negative selection	5772432
77989640	77989663	X	-	27260156	A375	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.0025668443910851213	[166]	[135,141,266,221]	0	hSpCas9	negative selection	5772433
77988381	77988404	X	-	27260156	A375	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.28274699914145385	[629]	[459,866,635,501]	-4	hSpCas9	negative selection	5772434
77998643	77998666	X	-	27260156	A375	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	0.03905411288149885	[706]	[661,977,871,889]	0	hSpCas9	negative selection	5836716
77998473	77998496	X	+	27260156	A375	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.1792255677206131	[737]	[518,1024,752,777]	-3	hSpCas9	negative selection	5836717
78046361	78046384	X	+	27260156	A375	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.03803370973940157	[687]	[631,800,764,914]	0	hSpCas9	negative selection	5836718
77989904	77989927	X	-	27260156	COLO741	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.042489316291724144	[209]	[274,272,279]	0	hSpCas9	negative selection	5893683
77989640	77989663	X	-	27260156	COLO741	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.013624765072280498	[166]	[154,301,185]	0	hSpCas9	negative selection	5893684
77988381	77988404	X	-	27260156	COLO741	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.07891755322109728	[629]	[904,1072,594]	1	hSpCas9	negative selection	5893685
77998643	77998666	X	-	27260156	COLO741	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.12516872364674647	[706]	[965,778,754]	-3	hSpCas9	negative selection	5957967
77998473	77998496	X	+	27260156	COLO741	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.023905693651978144	[737]	[928,1196,673]	0	hSpCas9	negative selection	5957968
78046361	78046384	X	+	27260156	COLO741	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.19986047192389195	[687]	[739,769,780]	-4	hSpCas9	negative selection	5957969
77989904	77989927	X	-	27260156	CAL120	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.1332119569543111	[209]	[209,286,349]	2	hSpCas9	negative selection	6014934
77989640	77989663	X	-	27260156	CAL120	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.7579708915169214	[166]	[631,259,206]	9	hSpCas9	negative selection	6014935
77988381	77988404	X	-	27260156	CAL120	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.2041397110860582	[629]	[826,760,478]	-3	hSpCas9	negative selection	6014936
77998643	77998666	X	-	27260156	CAL120	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.08519383287149096	[706]	[696,787,979]	-1	hSpCas9	negative selection	6079218
77998473	77998496	X	+	27260156	CAL120	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.042151656733627973	[737]	[961,668,1051]	0	hSpCas9	negative selection	6079219
78046361	78046384	X	+	27260156	CAL120	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.13411252856169814	[687]	[1492,601,359]	-2	hSpCas9	negative selection	6079220
77989904	77989927	X	-	27260156	CADOES1	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.41453355282898896	[209]	[170,240,329,300]	7	hSpCas9	negative selection	6136185
77989640	77989663	X	-	27260156	CADOES1	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.16882921612483903	[166]	[142,129,183,243]	3	hSpCas9	negative selection	6136186
77988381	77988404	X	-	27260156	CADOES1	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.11889030503009296	[629]	[497,610,499,549]	-2	hSpCas9	negative selection	6136187
77998643	77998666	X	-	27260156	CADOES1	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.10097423438402164	[706]	[508,658,639,645]	-2	hSpCas9	negative selection	6200469
77998473	77998496	X	+	27260156	CADOES1	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.14903529124198267	[737]	[645,415,527,895]	-3	hSpCas9	negative selection	6200470
78046361	78046384	X	+	27260156	CADOES1	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.6502599036337613	[687]	[445,372,420,389]	-8	hSpCas9	negative selection	6200471
77989904	77989927	X	-	27260156	EWS502	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.6225326289583542	[209]	[439,160,342,425]	9	hSpCas9	negative selection	6257436
77989640	77989663	X	-	27260156	EWS502	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.052612469659010674	[166]	[113,105,299,172]	-1	hSpCas9	negative selection	6257437
77988381	77988404	X	-	27260156	EWS502	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.37571737308321085	[629]	[488,365,533,687]	-6	hSpCas9	negative selection	6257438
77998643	77998666	X	-	27260156	EWS502	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.2664164872654594	[706]	[686,603,614,570]	-5	hSpCas9	negative selection	6321720
77998473	77998496	X	+	27260156	EWS502	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.4527007988891912	[737]	[421,667,594,614]	-6	hSpCas9	negative selection	6321721
78046361	78046384	X	+	27260156	EWS502	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.41523946350062746	[687]	[439,550,628,579]	-6	hSpCas9	negative selection	6321722
77989904	77989927	X	-	27260156	EW8	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.2871323213138671	[209]	[204,160,191,273]	5	hSpCas9	negative selection	6378687
77989640	77989663	X	-	27260156	EW8	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.12136323954220285	[166]	[134,113,132,114]	-2	hSpCas9	negative selection	6378688
77988381	77988404	X	-	27260156	EW8	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.011308327555994702	[629]	[800,611,363,337]	0	hSpCas9	negative selection	6378689
77998643	77998666	X	-	27260156	EW8	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.16847546445106565	[706]	[629,621,438,372]	-3	hSpCas9	negative selection	6442971
77998473	77998496	X	+	27260156	EW8	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.2205957869518208	[737]	[605,622,398,453]	-4	hSpCas9	negative selection	6442972
78046361	78046384	X	+	27260156	EW8	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.46011419343534726	[687]	[364,440,373,440]	-7	hSpCas9	negative selection	6442973
77989904	77989927	X	-	27260156	CORL105	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.6444474705658577	[209]	[358,282,492,419]	9	hSpCas9	negative selection	6499938
77989640	77989663	X	-	27260156	CORL105	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.05284052986599641	[166]	[227,135,174,214]	-1	hSpCas9	negative selection	6499939
77988381	77988404	X	-	27260156	CORL105	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.15430376937955637	[629]	[983,711,846,751]	3	hSpCas9	negative selection	6499940
77998643	77998666	X	-	27260156	CORL105	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.19466892098414096	[706]	[638,677,841,749]	-4	hSpCas9	negative selection	6564222
77998473	77998496	X	+	27260156	CORL105	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.020456013129357187	[737]	[710,850,1179,711]	0	hSpCas9	negative selection	6564223
78046361	78046384	X	+	27260156	CORL105	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.19773303035959305	[687]	[775,630,684,717]	-4	hSpCas9	negative selection	6564224
77989904	77989927	X	-	27260156	HS294T	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.2815569110036511	[209]	[107,81,100,103]	4	hSpCas9	negative selection	6621189
77989640	77989663	X	-	27260156	HS294T	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.4665367792275348	[166]	[38,33,42,76]	-6	hSpCas9	negative selection	6621190
77988381	77988404	X	-	27260156	HS294T	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.04931558035871253	[629]	[277,247,180,227]	0	hSpCas9	negative selection	6621191
77998643	77998666	X	-	27260156	HS294T	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.448751409820741	[706]	[155,187,161,318]	-6	hSpCas9	negative selection	6685473
77998473	77998496	X	+	27260156	HS294T	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	0.05629710561150403	[737]	[274,358,223,333]	0	hSpCas9	negative selection	6685474
78046361	78046384	X	+	27260156	HS294T	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.3364454666743841	[687]	[205,283,163,180]	-5	hSpCas9	negative selection	6685475
77989904	77989927	X	-	27260156	HCC44	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.25632985382456275	[209]	[339,339,276,174]	4	hSpCas9	negative selection	6742440
77989640	77989663	X	-	27260156	HCC44	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.3424778009791343	[166]	[148,122,176,153]	-5	hSpCas9	negative selection	6742441
77988381	77988404	X	-	27260156	HCC44	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.01159020708210573	[629]	[900,607,752,645]	0	hSpCas9	negative selection	6742442
77998643	77998666	X	-	27260156	HCC44	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.30173762644712515	[706]	[850,463,735,599]	-5	hSpCas9	negative selection	6806724
77998473	77998496	X	+	27260156	HCC44	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.17816996238923039	[737]	[819,614,863,693]	-3	hSpCas9	negative selection	6806725
78046361	78046384	X	+	27260156	HCC44	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.34802614064730103	[687]	[531,517,722,689]	-5	hSpCas9	negative selection	6806726
77989904	77989927	X	-	27260156	G402	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.6804017117442513	[209]	[275,402,634,311]	8	hSpCas9	negative selection	6863691
77989640	77989663	X	-	27260156	G402	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.4847597870275395	[166]	[196,332,323,275]	6	hSpCas9	negative selection	6863692
77988381	77988404	X	-	27260156	G402	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.12631342603158624	[629]	[844,830,1041,644]	1	hSpCas9	negative selection	6863693
77998643	77998666	X	-	27260156	G402	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.033729562407376124	[706]	[1415,751,450,826]	0	hSpCas9	negative selection	6927975
77998473	77998496	X	+	27260156	G402	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.3341386887058436	[737]	[937,547,481,899]	-4	hSpCas9	negative selection	6927976
78046361	78046384	X	+	27260156	G402	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.002980223562819573	[687]	[802,1111,1183,286]	0	hSpCas9	negative selection	6927977
77989904	77989927	X	-	27260156	L33	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.2258056253424332	[209]	[337,81,143,212]	5	hSpCas9	negative selection	6984942
77989640	77989663	X	-	27260156	L33	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.03587571014112445	[166]	[110,61,125,189]	-1	hSpCas9	negative selection	6984943
77988381	77988404	X	-	27260156	L33	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.07285020425616834	[629]	[630,294,446,589]	1	hSpCas9	negative selection	6984944
77998643	77998666	X	-	27260156	L33	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.1993818989706374	[706]	[786,228,330,585]	-4	hSpCas9	negative selection	7049226
77998473	77998496	X	+	27260156	L33	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.21696128049646518	[737]	[516,287,427,641]	-5	hSpCas9	negative selection	7049227
78046361	78046384	X	+	27260156	L33	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.37006925929769596	[687]	[607,207,382,403]	-7	hSpCas9	negative selection	7049228
77989904	77989927	X	-	27260156	K562	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	1.0430556082697566	[209]	[280,284,704,263]	9	hSpCas9	negative selection	7106193
77989640	77989663	X	-	27260156	K562	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.1536011752290487	[166]	[309,161,38,159]	2	hSpCas9	negative selection	7106194
77988381	77988404	X	-	27260156	K562	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.5572520937796188	[629]	[469,407,334,320]	-6	hSpCas9	negative selection	7106195
77998643	77998666	X	-	27260156	K562	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.47344288891697206	[706]	[382,601,475,357]	-5	hSpCas9	negative selection	7170477
77998473	77998496	X	+	27260156	K562	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.04084536311353493	[737]	[1145,472,585,399]	0	hSpCas9	negative selection	7170478
78046361	78046384	X	+	27260156	K562	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.6918627675447909	[687]	[464,317,454,286]	-7	hSpCas9	negative selection	7170479
77989904	77989927	X	-	27260156	HT29	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.3559813094091222	[209]	[240,445,346,279]	7	hSpCas9	negative selection	7227444
77989640	77989663	X	-	27260156	HT29	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.15630833554761292	[166]	[178,215,161,173]	-3	hSpCas9	negative selection	7227445
77988381	77988404	X	-	27260156	HT29	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.04257933071611619	[629]	[809,877,765,713]	0	hSpCas9	negative selection	7227446
77998643	77998666	X	-	27260156	HT29	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.3199142725293555	[706]	[752,691,734,586]	-6	hSpCas9	negative selection	7291728
77998473	77998496	X	+	27260156	HT29	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.06199917355456752	[737]	[1053,963,638,804]	-1	hSpCas9	negative selection	7291729
78046361	78046384	X	+	27260156	HT29	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.2356253571045206	[687]	[802,610,775,651]	-5	hSpCas9	negative selection	7291730
77989904	77989927	X	-	27260156	MHHES1	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	-0.32738804545278133	[209]	[184,199,129,225]	-6	hSpCas9	negative selection	7348695
77989640	77989663	X	-	27260156	MHHES1	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.647749118339922	[166]	[64,243,99,82]	-8	hSpCas9	negative selection	7348696
77988381	77988404	X	-	27260156	MHHES1	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.07912893555796974	[629]	[491,790,890,523]	-1	hSpCas9	negative selection	7348697
77998643	77998666	X	-	27260156	MHHES1	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.019799760174268544	[706]	[1035,655,1007,507]	0	hSpCas9	negative selection	7412979
77998473	77998496	X	+	27260156	MHHES1	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.23316997808619216	[737]	[718,783,743,599]	-4	hSpCas9	negative selection	7412980
78046361	78046384	X	+	27260156	MHHES1	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.539868698809733	[687]	[567,504,591,470]	-7	hSpCas9	negative selection	7412981
77989904	77989927	X	-	27260156	MEWO	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.5931651212957199	[209]	[474,231,216]	9	hSpCas9	negative selection	7469946
77989640	77989663	X	-	27260156	MEWO	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.35993555950453926	[166]	[248,176,184]	7	hSpCas9	negative selection	7469947
77988381	77988404	X	-	27260156	MEWO	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.20360239255191226	[629]	[668,473,422]	-4	hSpCas9	negative selection	7469948
77998643	77998666	X	-	27260156	MEWO	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.6365290174757051	[706]	[485,438,362]	-8	hSpCas9	negative selection	7534230
77998473	77998496	X	+	27260156	MEWO	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	0.03583225870624174	[737]	[915,625,621]	0	hSpCas9	negative selection	7534231
78046361	78046384	X	+	27260156	MEWO	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.24627412200887494	[687]	[610,560,468]	-5	hSpCas9	negative selection	7534232
77989904	77989927	X	-	27260156	LNCAPCLONEFGC	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.46549032287305736	[209]	[270,280,207,280]	7	hSpCas9	negative selection	7591197
77989640	77989663	X	-	27260156	LNCAPCLONEFGC	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.2545357246670288	[166]	[112,120,208,76]	-4	hSpCas9	negative selection	7591198
77988381	77988404	X	-	27260156	LNCAPCLONEFGC	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-1.063853374604364	[629]	[252,298,269,267]	-9	hSpCas9	negative selection	7591199
77998643	77998666	X	-	27260156	LNCAPCLONEFGC	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.25369955565854835	[706]	[586,584,616,366]	-4	hSpCas9	negative selection	7655481
77998473	77998496	X	+	27260156	LNCAPCLONEFGC	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.48599995989191813	[737]	[555,400,473,480]	-6	hSpCas9	negative selection	7655482
78046361	78046384	X	+	27260156	LNCAPCLONEFGC	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.27418034691849796	[687]	[359,571,613,528]	-4	hSpCas9	negative selection	7655483
77989904	77989927	X	-	27260156	PANC0327	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.007386490217683672	[209]	[341,90,144,196]	0	hSpCas9	negative selection	7712448
77989640	77989663	X	-	27260156	PANC0327	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.09710784857096666	[166]	[77,220,160,159]	1	hSpCas9	negative selection	7712449
77988381	77988404	X	-	27260156	PANC0327	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.29371848914971	[629]	[661,694,413,968]	4	hSpCas9	negative selection	7712450
77998643	77998666	X	-	27260156	PANC0327	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.771525606561443	[706]	[398,289,342,451]	-8	hSpCas9	negative selection	7776732
77998473	77998496	X	+	27260156	PANC0327	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	0.15578178604551607	[737]	[896,603,707,741]	2	hSpCas9	negative selection	7776733
78046361	78046384	X	+	27260156	PANC0327	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.3067003812350688	[687]	[690,377,295,641]	-4	hSpCas9	negative selection	7776734
77989904	77989927	X	-	27260156	NCIH2009	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.7838362670056089	[209]	[546,442,533]	9	hSpCas9	negative selection	7833699
77989640	77989663	X	-	27260156	NCIH2009	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.03483481456360993	[166]	[275,140,276]	0	hSpCas9	negative selection	7833700
77988381	77988404	X	-	27260156	NCIH2009	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.13863767822562462	[629]	[771,902,714]	-2	hSpCas9	negative selection	7833701
77998643	77998666	X	-	27260156	NCIH2009	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.36178100690846704	[706]	[1022,661,671]	-5	hSpCas9	negative selection	7897983
77998473	77998496	X	+	27260156	NCIH2009	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.4401004598187297	[737]	[994,769,559]	-5	hSpCas9	negative selection	7897984
78046361	78046384	X	+	27260156	NCIH2009	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.133215747454893	[687]	[1016,747,892]	-2	hSpCas9	negative selection	7897985
77989904	77989927	X	-	27260156	NCIH1373	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	1.7814001454503607	[209]	[1254,336,1346,98]	9	hSpCas9	negative selection	7954950
77989640	77989663	X	-	27260156	NCIH1373	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.7974864048157748	[166]	[505,271,219,88]	7	hSpCas9	negative selection	7954951
77988381	77988404	X	-	27260156	NCIH1373	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.17818352587058273	[629]	[594,729,1163,173]	1	hSpCas9	negative selection	7954952
77998643	77998666	X	-	27260156	NCIH1373	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.09002612840825253	[706]	[987,716,651,171]	-1	hSpCas9	negative selection	8019234
77998473	77998496	X	+	27260156	NCIH1373	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.654860311835681	[737]	[516,688,393,125]	-6	hSpCas9	negative selection	8019235
78046361	78046384	X	+	27260156	NCIH1373	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.5243668904539595	[687]	[580,576,335,173]	-5	hSpCas9	negative selection	8019236
77989904	77989927	X	-	27260156	PATU8902	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.6569266641825088	[209]	[676,483,267,458]	7	hSpCas9	negative selection	8076201
77989640	77989663	X	-	27260156	PATU8902	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.08332154296260641	[166]	[246,169,120,382]	-1	hSpCas9	negative selection	8076202
77988381	77988404	X	-	27260156	PATU8902	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.4641292791984267	[629]	[1542,994,1292,941]	5	hSpCas9	negative selection	8076203
77998643	77998666	X	-	27260156	PATU8902	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.09484077782078582	[706]	[1009,637,851,1233]	-1	hSpCas9	negative selection	8140485
77998473	77998496	X	+	27260156	PATU8902	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	0.05175913133982368	[737]	[662,1287,1099,1216]	0	hSpCas9	negative selection	8140486
78046361	78046384	X	+	27260156	PATU8902	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.6773829489186289	[687]	[802,614,383,648]	-6	hSpCas9	negative selection	8140487
77989904	77989927	X	-	27260156	PANC1	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.3088364099922648	[209]	[295,227,209,164]	5	hSpCas9	negative selection	8197452
77989640	77989663	X	-	27260156	PANC1	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.23767390750669692	[166]	[65,110,111,183]	-4	hSpCas9	negative selection	8197453
77988381	77988404	X	-	27260156	PANC1	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.09535181774034851	[629]	[428,595,508,503]	-1	hSpCas9	negative selection	8197454
77998643	77998666	X	-	27260156	PANC1	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.11308979497282312	[706]	[474,713,668,433]	-2	hSpCas9	negative selection	8261736
77998473	77998496	X	+	27260156	PANC1	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.08611381617756775	[737]	[635,725,609,455]	-1	hSpCas9	negative selection	8261737
78046361	78046384	X	+	27260156	PANC1	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	0.030303370131105845	[687]	[547,591,447,782]	0	hSpCas9	negative selection	8261738
77989904	77989927	X	-	27260156	PANC0813	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.6594165298742392	[209]	[285,428,521,315]	9	hSpCas9	negative selection	8318703
77989640	77989663	X	-	27260156	PANC0813	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.12110503685653029	[166]	[251,240,213,152]	2	hSpCas9	negative selection	8318704
77988381	77988404	X	-	27260156	PANC0813	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.3708717150388112	[629]	[1337,886,898,748]	6	hSpCas9	negative selection	8318705
77998643	77998666	X	-	27260156	PANC0813	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.3894299192891093	[706]	[561,630,518,805]	-6	hSpCas9	negative selection	8382987
77998473	77998496	X	+	27260156	PANC0813	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	0.031858937807183185	[737]	[1160,796,703,904]	0	hSpCas9	negative selection	8382988
78046361	78046384	X	+	27260156	PANC0813	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.3088539543893909	[687]	[867,682,537,544]	-5	hSpCas9	negative selection	8382989
77989904	77989927	X	-	27260156	RDES	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.5659765418174983	[209]	[220,380,513,333]	8	hSpCas9	negative selection	8439954
77989640	77989663	X	-	27260156	RDES	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.4121308903139207	[166]	[210,237,259,327]	6	hSpCas9	negative selection	8439955
77988381	77988404	X	-	27260156	RDES	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.042358535359344196	[629]	[519,665,750,937]	0	hSpCas9	negative selection	8439956
77998643	77998666	X	-	27260156	RDES	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.34840832311021974	[706]	[466,666,659,801]	-5	hSpCas9	negative selection	8504238
77998473	77998496	X	+	27260156	RDES	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.14055672103835126	[737]	[679,815,714,871]	-2	hSpCas9	negative selection	8504239
78046361	78046384	X	+	27260156	RDES	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.22258993813679206	[687]	[633,604,647,843]	-4	hSpCas9	negative selection	8504240
77989904	77989927	X	-	27260156	PC3	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	-0.02642707933893096	[209]	[186,224,253,150]	0	hSpCas9	negative selection	8561205
77989640	77989663	X	-	27260156	PC3	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.08316621584979167	[166]	[128,173,200,131]	-2	hSpCas9	negative selection	8561206
77988381	77988404	X	-	27260156	PC3	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.30629369658155237	[629]	[255,448,791,727]	-6	hSpCas9	negative selection	8561207
77998643	77998666	X	-	27260156	PC3	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.7732960365079032	[706]	[344,356,697,337]	-9	hSpCas9	negative selection	8625489
77998473	77998496	X	+	27260156	PC3	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.13917415224200191	[737]	[420,562,989,881]	-3	hSpCas9	negative selection	8625490
78046361	78046384	X	+	27260156	PC3	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.106958575884258	[687]	[384,631,1181,609]	-2	hSpCas9	negative selection	8625491
77989904	77989927	X	-	27260156	PATU8988T	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.6179897460825835	[209]	[328,161,271,482]	8	hSpCas9	negative selection	8682456
77989640	77989663	X	-	27260156	PATU8988T	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.19596154257033538	[166]	[128,164,119,152]	-3	hSpCas9	negative selection	8682457
77988381	77988404	X	-	27260156	PATU8988T	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.42741528287978736	[629]	[947,732,789,793]	7	hSpCas9	negative selection	8682458
77998643	77998666	X	-	27260156	PATU8988T	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.48947468839035335	[706]	[584,496,270,606]	-7	hSpCas9	negative selection	8746740
77998473	77998496	X	+	27260156	PATU8988T	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	0.05299346895131085	[737]	[656,898,745,665]	0	hSpCas9	negative selection	8746741
78046361	78046384	X	+	27260156	PATU8988T	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.14234064443768252	[687]	[775,489,499,636]	-2	hSpCas9	negative selection	8746742
77989904	77989927	X	-	27260156	T47D	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.20362524043829344	[209]	[248,269,285,323]	4	hSpCas9	negative selection	8803707
77989640	77989663	X	-	27260156	T47D	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.051677870574821094	[166]	[237,139,150,227]	-1	hSpCas9	negative selection	8803708
77988381	77988404	X	-	27260156	T47D	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.06315764908291399	[629]	[781,784,729,768]	1	hSpCas9	negative selection	8803709
77998643	77998666	X	-	27260156	T47D	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.2355664850122472	[706]	[684,548,799,777]	-5	hSpCas9	negative selection	8867991
77998473	77998496	X	+	27260156	T47D	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.06167193120340464	[737]	[914,793,861,722]	-1	hSpCas9	negative selection	8867992
78046361	78046384	X	+	27260156	T47D	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.27899649831221884	[687]	[646,631,659,706]	-6	hSpCas9	negative selection	8867993
77989904	77989927	X	-	27260156	SU8686	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.5133190310954389	[209]	[261,251,355,333]	8	hSpCas9	negative selection	8924958
77989640	77989663	X	-	27260156	SU8686	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	0.21574892852231753	[166]	[130,158,274,220]	3	hSpCas9	negative selection	8924959
77988381	77988404	X	-	27260156	SU8686	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.25541101294676416	[629]	[767,603,749,894]	4	hSpCas9	negative selection	8924960
77998643	77998666	X	-	27260156	SU8686	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.19283838522629987	[706]	[553,610,748,531]	-3	hSpCas9	negative selection	8989242
77998473	77998496	X	+	27260156	SU8686	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.2053540323463438	[737]	[566,774,490,695]	-4	hSpCas9	negative selection	8989243
78046361	78046384	X	+	27260156	SU8686	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.3924389930304918	[687]	[551,442,488,610]	-6	hSpCas9	negative selection	8989244
77989904	77989927	X	-	27260156	SKES1	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.2327265653025795	[209]	[188,255,223,299]	5	hSpCas9	negative selection	9046209
77989640	77989663	X	-	27260156	SKES1	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.14421662671325652	[166]	[141,144,199,115]	-3	hSpCas9	negative selection	9046210
77988381	77988404	X	-	27260156	SKES1	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.07296922047503579	[629]	[792,571,740,550]	1	hSpCas9	negative selection	9046211
77998643	77998666	X	-	27260156	SKES1	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.5052262205118936	[706]	[582,599,371,457]	-8	hSpCas9	negative selection	9110493
77998473	77998496	X	+	27260156	SKES1	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.28674226223622185	[737]	[622,746,575,494]	-6	hSpCas9	negative selection	9110494
78046361	78046384	X	+	27260156	SKES1	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.30627510162737726	[687]	[596,635,533,472]	-6	hSpCas9	negative selection	9110495
77989904	77989927	X	-	27260156	TOV112D	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.6989702427094744	[209]	[479,451,237,236]	9	hSpCas9	negative selection	9167460
77989640	77989663	X	-	27260156	TOV112D	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.44322292916540995	[166]	[147,82,161,91]	-7	hSpCas9	negative selection	9167461
77988381	77988404	X	-	27260156	TOV112D	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	0.012961162464038556	[629]	[506,892,604,593]	0	hSpCas9	negative selection	9167462
77998643	77998666	X	-	27260156	TOV112D	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.33609429630235693	[706]	[426,694,597,544]	-6	hSpCas9	negative selection	9231744
77998473	77998496	X	+	27260156	TOV112D	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.21190759608398096	[737]	[615,746,772,445]	-4	hSpCas9	negative selection	9231745
78046361	78046384	X	+	27260156	TOV112D	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.33676723223131955	[687]	[599,676,487,455]	-6	hSpCas9	negative selection	9231746
77989904	77989927	X	-	27260156	TC71	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.21244200009381353	[209]	[285,294,168,297]	5	hSpCas9	negative selection	9288711
77989640	77989663	X	-	27260156	TC71	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.03956912127755463	[166]	[150,180,186,177]	-1	hSpCas9	negative selection	9288712
77988381	77988404	X	-	27260156	TC71	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.09898706704004018	[629]	[784,550,565,617]	-3	hSpCas9	negative selection	9288713
77998643	77998666	X	-	27260156	TC71	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.2379609486016217	[706]	[660,754,606,541]	-6	hSpCas9	negative selection	9352995
77998473	77998496	X	+	27260156	TC71	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.14627004252865328	[737]	[741,605,862,637]	-4	hSpCas9	negative selection	9352996
78046361	78046384	X	+	27260156	TC71	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.29379196938276014	[687]	[506,708,569,624]	-7	hSpCas9	negative selection	9352997
77989904	77989927	X	-	27260156	TC32	viability	ATTGCTCCTCTCAACGTTTCTGG	ATP7A	ENSG00000165240	0.1955887571855035	[209]	[249,163,304,203]	3	hSpCas9	negative selection	9409962
77989640	77989663	X	-	27260156	TC32	viability	ATACTAACTCTATATAGCCCCGG	ATP7A	ENSG00000165240	-0.442909294596598	[166]	[143,71,116,135]	-7	hSpCas9	negative selection	9409963
77988381	77988404	X	-	27260156	TC32	viability	CGCCGTAACAGTCAGAAACAAGG	ATP7A	ENSG00000165240	-0.5105373962309355	[629]	[376,287,582,475]	-7	hSpCas9	negative selection	9409964
77998643	77998666	X	-	27260156	TC32	viability	CCGTTCAATGTTTGCTACACAGG	ATP7A	ENSG00000165240	-0.26371642401903983	[706]	[549,403,762,556]	-5	hSpCas9	negative selection	9474246
77998473	77998496	X	+	27260156	TC32	viability	ACCAGACACGAATGAGCCGTTGG	ATP7A	ENSG00000165240	-0.27128667940626305	[737]	[504,453,693,692]	-5	hSpCas9	negative selection	9474247
78046361	78046384	X	+	27260156	TC32	viability	TCAGAAATCAGCGTTCATGTTGG	ATP7A	ENSG00000165240	-0.35611416033322707	[687]	[556,395,553,525]	-6	hSpCas9	negative selection	9474248
77971703	77971726	X	-	27869803	HPAFII	viability after 27 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.5063451592993562	[819]	[325,850,NaN]	4	hSpCas9	negative selection	9609666
77988605	77988628	X	+	27869803	HPAFII	viability after 27 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.8483248290568481	[131]	[37,38,NaN]	-5	hSpCas9	negative selection	9609667
77989622	77989645	X	+	27869803	HPAFII	viability after 27 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	0.5469468158616181	[166]	[106,145,NaN]	4	hSpCas9	negative selection	9609668
77998563	77998586	X	+	27869803	HPAFII	viability after 27 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.4547749412429527	[163]	[75,51,NaN]	-3	hSpCas9	negative selection	9609669
78009181	78009204	X	-	27869803	HPAFII	viability after 27 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	-0.2728749750021533	[177]	[71,81,NaN]	-2	hSpCas9	negative selection	9609670
78013072	78013095	X	+	27869803	HPAFII	viability after 27 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	0.7650650426176955	[127]	[109,117,NaN]	6	hSpCas9	negative selection	9609671
77971703	77971726	X	-	27869803	HPAFII	viability after 15 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.09210232718569156	[819]	[1021,887,NaN]	1	hSpCas9	negative selection	9692115
77988605	77988628	X	+	27869803	HPAFII	viability after 15 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.09291349385745917	[131]	[124,137,NaN]	-1	hSpCas9	negative selection	9692116
77989622	77989645	X	+	27869803	HPAFII	viability after 15 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	0.4672061923985872	[166]	[265,236,NaN]	5	hSpCas9	negative selection	9692117
77998563	77998586	X	+	27869803	HPAFII	viability after 15 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.07118260231584594	[163]	[205,143,NaN]	0	hSpCas9	negative selection	9692118
78009181	78009204	X	-	27869803	HPAFII	viability after 15 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.1468655058484885	[177]	[233,197,NaN]	1	hSpCas9	negative selection	9692119
78013072	78013095	X	+	27869803	HPAFII	viability after 15 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	0.13400838536571757	[127]	[211,112,NaN]	1	hSpCas9	negative selection	9692120
77971703	77971726	X	-	27869803	ASPC1	viability after 36 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-0.8399219387668228	[1897]	[409,498,235]	-7	hSpCas9	negative selection	9774564
77988605	77988628	X	+	27869803	ASPC1	viability after 36 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.0816276219994474	[310]	[84,114,103]	-1	hSpCas9	negative selection	9774565
77989622	77989645	X	+	27869803	ASPC1	viability after 36 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	-0.28013105715439557	[493]	[167,159,107]	-3	hSpCas9	negative selection	9774566
77998563	77998586	X	+	27869803	ASPC1	viability after 36 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.9453629665017148	[401]	[83,105,37]	-7	hSpCas9	negative selection	9774567
78009181	78009204	X	-	27869803	ASPC1	viability after 36 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.13395386019754368	[411]	[212,78,179]	1	hSpCas9	negative selection	9774568
78013072	78013095	X	+	27869803	ASPC1	viability after 36 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-1.1533966540323215	[252]	[77,9,35]	-8	hSpCas9	negative selection	9774569
77971703	77971726	X	-	27869803	PATU8988S	viability after 35 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.1224680694721072	[1606]	[730,677,NaN]	1	hSpCas9	negative selection	9857013
77988605	77988628	X	+	27869803	PATU8988S	viability after 35 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.8292465650817764	[310]	[68,71,NaN]	-7	hSpCas9	negative selection	9857014
77989622	77989645	X	+	27869803	PATU8988S	viability after 35 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	-1.3416143065655208	[449]	[76,65,NaN]	-8	hSpCas9	negative selection	9857015
77998563	77998586	X	+	27869803	PATU8988S	viability after 35 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-1.533478874459679	[337]	[57,35,NaN]	-8	hSpCas9	negative selection	9857016
78009181	78009204	X	-	27869803	PATU8988S	viability after 35 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	-0.15679820458609356	[425]	[110,196,NaN]	-2	hSpCas9	negative selection	9857017
78013072	78013095	X	+	27869803	PATU8988S	viability after 35 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-0.4695310270802413	[212]	[41,81,NaN]	-5	hSpCas9	negative selection	9857018
77971703	77971726	X	-	27869803	PATU8988S	viability after 31 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	-0.1918009048937579	[1606]	[421,737,NaN]	-2	hSpCas9	negative selection	9939462
77988605	77988628	X	+	27869803	PATU8988S	viability after 31 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.30186911519494575	[310]	[82,122,NaN]	-3	hSpCas9	negative selection	9939463
77989622	77989645	X	+	27869803	PATU8988S	viability after 31 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	-0.761030181840941	[449]	[104,106,NaN]	-7	hSpCas9	negative selection	9939464
77998563	77998586	X	+	27869803	PATU8988S	viability after 31 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-1.216374847060158	[337]	[68,43,NaN]	-8	hSpCas9	negative selection	9939465
78009181	78009204	X	-	27869803	PATU8988S	viability after 31 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	-0.3023042343274632	[425]	[102,181,NaN]	-3	hSpCas9	negative selection	9939466
78013072	78013095	X	+	27869803	PATU8988S	viability after 31 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	-1.084924651049053	[212]	[32,48,NaN]	-8	hSpCas9	negative selection	9939467
77971703	77971726	X	-	27869803	HPAFII	viability after 35 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.5007380111953672	[819]	[267,946,NaN]	3	hSpCas9	negative selection	10021911
77988605	77988628	X	+	27869803	HPAFII	viability after 35 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-0.6663269953139606	[131]	[19,66,NaN]	-4	hSpCas9	negative selection	10021912
77989622	77989645	X	+	27869803	HPAFII	viability after 35 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	1.5980723794421716	[166]	[143,381,NaN]	9	hSpCas9	negative selection	10021913
77998563	77998586	X	+	27869803	HPAFII	viability after 35 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	0.10046218065187318	[163]	[112,61,NaN]	0	hSpCas9	negative selection	10021914
78009181	78009204	X	-	27869803	HPAFII	viability after 35 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.0018151951420367074	[177]	[69,112,NaN]	0	hSpCas9	negative selection	10021915
78013072	78013095	X	+	27869803	HPAFII	viability after 35 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	0.5375870676067114	[127]	[94,92,NaN]	3	hSpCas9	negative selection	10021916
77971703	77971726	X	-	27869803	HPAFII	viability after 31 days	CTGCTCAATGGTCCAAACACAGG	ATP7A	ENSG00000165240	0.5376262455013172	[819]	[377,983,NaN]	4	hSpCas9	negative selection	10104360
77988605	77988628	X	+	27869803	HPAFII	viability after 31 days	GATCATAGTATGGCTCAAGCTGG	ATP7A	ENSG00000165240	-1.2705205416448606	[131]	[12,49,NaN]	-6	hSpCas9	negative selection	10104361
77989622	77989645	X	+	27869803	HPAFII	viability after 31 days	GCAATAGAGGCTGTATCACCGGG	ATP7A	ENSG00000165240	1.1672943747359152	[166]	[120,307,NaN]	8	hSpCas9	negative selection	10104362
77998563	77998586	X	+	27869803	HPAFII	viability after 31 days	GATGACACCAGTTCAAGACAAGG	ATP7A	ENSG00000165240	-0.5088055790559103	[163]	[79,47,NaN]	-3	hSpCas9	negative selection	10104363
78009181	78009204	X	-	27869803	HPAFII	viability after 31 days	TTTGTTGGTTGCCAGGGCCACGG	ATP7A	ENSG00000165240	0.3480254205116038	[177]	[163,86,NaN]	2	hSpCas9	negative selection	10104364
78013072	78013095	X	+	27869803	HPAFII	viability after 31 days	TGTTTATTGCACTAGGCCGATGG	ATP7A	ENSG00000165240	0.7035597552629751	[127]	[71,165,NaN]	5	hSpCas9	negative selection	10104365
77989623	77989646	X	+	28162770	P31FUJ	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.3120828569314425	[145]	[212]	3	hSpCas9	negative selection	10116126
77989915	77989938	X	+	28162770	P31FUJ	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.08338190793817996	[150]	[187]	0	hSpCas9	negative selection	10116127
77998566	77998589	X	+	28162770	P31FUJ	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	1.0302322014194152	[29]	[71]	9	hSpCas9	negative selection	10116128
78011527	78011550	X	-	28162770	P31FUJ	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.2653170363590203	[193]	[273]	3	hSpCas9	negative selection	10116129
78012967	78012990	X	-	28162770	P31FUJ	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.03972365039671283	[302]	[365]	0	hSpCas9	negative selection	10116130
78013091	78013114	X	+	28162770	P31FUJ	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.6791416189204253	[75]	[142]	7	hSpCas9	negative selection	10116131
78033604	78033627	X	+	28162770	P31FUJ	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	-0.0457166518138834	[324]	[369]	0	hSpCas9	negative selection	10116132
78042656	78042679	X	+	28162770	P31FUJ	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-0.5547302993017409	[19]	[15]	-5	hSpCas9	negative selection	10116133
78045482	78045505	X	-	28162770	P31FUJ	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	1.0580989948523591	[187]	[459]	9	hSpCas9	negative selection	10116134
77988359	77988382	X	-	28162770	P31FUJ	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.740502928920201	[299]	[588]	8	hSpCas9	negative selection	10116135
77989623	77989646	X	+	28162770	TF1	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	NaN	[NaN]	[113]	1	hSpCas9	negative selection	10285492
77989915	77989938	X	+	28162770	TF1	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	NaN	[NaN]	[57]	1	hSpCas9	negative selection	10285493
77998566	77998589	X	+	28162770	TF1	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10285494
78011527	78011550	X	-	28162770	TF1	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10285495
78012967	78012990	X	-	28162770	TF1	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	NaN	[NaN]	[231]	1	hSpCas9	negative selection	10285496
78013091	78013114	X	+	28162770	TF1	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10285497
78033604	78033627	X	+	28162770	TF1	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	NaN	[NaN]	[667]	1	hSpCas9	negative selection	10285498
78042656	78042679	X	+	28162770	TF1	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	NaN	[NaN]	[14]	1	hSpCas9	negative selection	10285499
78045482	78045505	X	-	28162770	TF1	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	NaN	[NaN]	[339]	1	hSpCas9	negative selection	10285500
77988359	77988382	X	-	28162770	TF1	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	NaN	[NaN]	[223]	1	hSpCas9	negative selection	10285501
77989623	77989646	X	+	28162770	SKM1	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.875071169020688	[32]	[106]	8	hSpCas9	negative selection	10454858
77989915	77989938	X	+	28162770	SKM1	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.6849582906978773	[37]	[107]	6	hSpCas9	negative selection	10454859
77998566	77998589	X	+	28162770	SKM1	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	0.9328858041414629	[7]	[26]	8	hSpCas9	negative selection	10454860
78011527	78011550	X	-	28162770	SKM1	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	-0.6495345020172401	[62]	[70]	-5	hSpCas9	negative selection	10454861
78012967	78012990	X	-	28162770	SKM1	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	-0.12052518857442418	[106]	[173]	-1	hSpCas9	negative selection	10454862
78013091	78013114	X	+	28162770	SKM1	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.4464871379038965	[21]	[52]	4	hSpCas9	negative selection	10454863
78033604	78033627	X	+	28162770	SKM1	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	1.227846851428556	[63]	[264]	9	hSpCas9	negative selection	10454864
78042656	78042679	X	+	28162770	SKM1	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-0.8220016980220053	[5]	[5]	-6	hSpCas9	negative selection	10454865
78045482	78045505	X	-	28162770	SKM1	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	-0.06016143521677003	[45]	[77]	0	hSpCas9	negative selection	10454866
77988359	77988382	X	-	28162770	SKM1	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	1.2617666596705923	[45]	[194]	9	hSpCas9	negative selection	10454867
77989623	77989646	X	+	28162770	SKM1	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.875071169020688	[32]	[106]	8	hSpCas9	negative selection	10624224
77989915	77989938	X	+	28162770	SKM1	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.6849582906978773	[37]	[107]	6	hSpCas9	negative selection	10624225
77998566	77998589	X	+	28162770	SKM1	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	0.9328858041414629	[7]	[26]	8	hSpCas9	negative selection	10624226
78011527	78011550	X	-	28162770	SKM1	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	-0.6495345020172401	[62]	[70]	-5	hSpCas9	negative selection	10624227
78012967	78012990	X	-	28162770	SKM1	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	-0.12052518857442418	[106]	[173]	-1	hSpCas9	negative selection	10624228
78013091	78013114	X	+	28162770	SKM1	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.4464871379038965	[21]	[52]	4	hSpCas9	negative selection	10624229
78033604	78033627	X	+	28162770	SKM1	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	1.227846851428556	[63]	[264]	9	hSpCas9	negative selection	10624230
78042656	78042679	X	+	28162770	SKM1	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-0.8220016980220053	[5]	[5]	-6	hSpCas9	negative selection	10624231
78045482	78045505	X	-	28162770	SKM1	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	-0.06016143521677003	[45]	[77]	0	hSpCas9	negative selection	10624232
77988359	77988382	X	-	28162770	SKM1	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	1.2617666596705923	[45]	[194]	9	hSpCas9	negative selection	10624233
77989623	77989646	X	+	28162770	PL21	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	1.0626360907393853	[120]	[109]	8	hSpCas9	negative selection	10793590
77989915	77989938	X	+	28162770	PL21	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.6508010234988852	[119]	[81]	5	hSpCas9	negative selection	10793591
77998566	77998589	X	+	28162770	PL21	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	0.030214613047007788	[35]	[15]	0	hSpCas9	negative selection	10793592
78011527	78011550	X	-	28162770	PL21	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.14517315527139177	[213]	[102]	1	hSpCas9	negative selection	10793593
78012967	78012990	X	-	28162770	PL21	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.42814663532319397	[402]	[235]	4	hSpCas9	negative selection	10793594
78013091	78013114	X	+	28162770	PL21	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.4307525426307366	[74]	[43]	4	hSpCas9	negative selection	10793595
78033604	78033627	X	+	28162770	PL21	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	1.270528942380718	[279]	[293]	9	hSpCas9	negative selection	10793596
78042656	78042679	X	+	28162770	PL21	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-1.6072153075682847	[6]	[0]	-8	hSpCas9	negative selection	10793597
78045482	78045505	X	-	28162770	PL21	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	1.5181096958079991	[145]	[181]	9	hSpCas9	negative selection	10793598
77988359	77988382	X	-	28162770	PL21	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.9871458911551219	[203]	[175]	8	hSpCas9	negative selection	10793599
77989623	77989646	X	+	28162770	P31FUJ	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.3120828569314425	[145]	[212]	3	hSpCas9	negative selection	10962956
77989915	77989938	X	+	28162770	P31FUJ	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.08338190793817996	[150]	[187]	0	hSpCas9	negative selection	10962957
77998566	77998589	X	+	28162770	P31FUJ	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	1.0302322014194152	[29]	[71]	9	hSpCas9	negative selection	10962958
78011527	78011550	X	-	28162770	P31FUJ	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.2653170363590203	[193]	[273]	3	hSpCas9	negative selection	10962959
78012967	78012990	X	-	28162770	P31FUJ	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.03972365039671283	[302]	[365]	0	hSpCas9	negative selection	10962960
78013091	78013114	X	+	28162770	P31FUJ	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.6791416189204253	[75]	[142]	7	hSpCas9	negative selection	10962961
78033604	78033627	X	+	28162770	P31FUJ	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	-0.0457166518138834	[324]	[369]	0	hSpCas9	negative selection	10962962
78042656	78042679	X	+	28162770	P31FUJ	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-0.5547302993017409	[19]	[15]	-5	hSpCas9	negative selection	10962963
78045482	78045505	X	-	28162770	P31FUJ	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	1.0580989948523591	[187]	[459]	9	hSpCas9	negative selection	10962964
77988359	77988382	X	-	28162770	P31FUJ	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.740502928920201	[299]	[588]	8	hSpCas9	negative selection	10962965
77989623	77989646	X	+	28162770	OCIAML5	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	1.4267928021314793	[33]	[164]	9	hSpCas9	negative selection	11132322
77989915	77989938	X	+	28162770	OCIAML5	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.5410055969180552	[90]	[238]	5	hSpCas9	negative selection	11132323
77998566	77998589	X	+	28162770	OCIAML5	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	-0.32599775919640894	[24]	[35]	-2	hSpCas9	negative selection	11132324
78011527	78011550	X	-	28162770	OCIAML5	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.042851383078445555	[120]	[224]	0	hSpCas9	negative selection	11132325
78012967	78012990	X	-	28162770	OCIAML5	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.2554318150482844	[264]	[570]	2	hSpCas9	negative selection	11132326
78013091	78013114	X	+	28162770	OCIAML5	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	1.5885060205219843	[20]	[113]	9	hSpCas9	negative selection	11132327
78033604	78033627	X	+	28162770	OCIAML5	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	0.6099684079520163	[150]	[415]	5	hSpCas9	negative selection	11132328
78042656	78042679	X	+	28162770	OCIAML5	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-5.552506289005089	[25]	[0]	-9	hSpCas9	negative selection	11132329
78045482	78045505	X	-	28162770	OCIAML5	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	-0.7646037296136576	[127]	[135]	-5	hSpCas9	negative selection	11132330
77988359	77988382	X	-	28162770	OCIAML5	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.354133816969865	[191]	[442]	3	hSpCas9	negative selection	11132331
77989623	77989646	X	+	28162770	EOL1	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	1.1686210883199335	[216]	[256]	8	hSpCas9	negative selection	11301688
77989915	77989938	X	+	28162770	EOL1	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	-0.5106676096459394	[191]	[70]	-4	hSpCas9	negative selection	11301689
77998566	77998589	X	+	28162770	EOL1	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	-0.7942704758854124	[78]	[23]	-5	hSpCas9	negative selection	11301690
78011527	78011550	X	-	28162770	EOL1	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.33011251822909604	[381]	[252]	3	hSpCas9	negative selection	11301691
78012967	78012990	X	-	28162770	EOL1	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.25851366020206046	[548]	[345]	2	hSpCas9	negative selection	11301692
78013091	78013114	X	+	28162770	EOL1	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	1.0934767805391228	[160]	[180]	8	hSpCas9	negative selection	11301693
78033604	78033627	X	+	28162770	EOL1	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	1.2275124624853022	[290]	[358]	8	hSpCas9	negative selection	11301694
78042656	78042679	X	+	28162770	EOL1	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	0.33958527084937806	[17]	[11]	3	hSpCas9	negative selection	11301695
78045482	78045505	X	-	28162770	EOL1	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	1.4270481120997178	[179]	[254]	9	hSpCas9	negative selection	11301696
77988359	77988382	X	-	28162770	EOL1	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	-0.6657481734536623	[270]	[89]	-5	hSpCas9	negative selection	11301697
77989623	77989646	X	+	28162770	MOLM13	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.10260491746283451	[151]	[117]	0	hSpCas9	negative selection	11471054
77989915	77989938	X	+	28162770	MOLM13	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	-1.816319047393625	[150]	[30]	-7	hSpCas9	negative selection	11471055
77998566	77998589	X	+	28162770	MOLM13	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	-1.8540387133427836	[49]	[9]	-7	hSpCas9	negative selection	11471056
78011527	78011550	X	-	28162770	MOLM13	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.4193092010995173	[301]	[291]	3	hSpCas9	negative selection	11471057
78012967	78012990	X	-	28162770	MOLM13	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.36704869203775115	[473]	[441]	2	hSpCas9	negative selection	11471058
78013091	78013114	X	+	28162770	MOLM13	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.9583650154104452	[162]	[228]	7	hSpCas9	negative selection	11471059
78033604	78033627	X	+	28162770	MOLM13	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	0.0022258091957670367	[347]	[251]	0	hSpCas9	negative selection	11471060
78042656	78042679	X	+	28162770	MOLM13	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-0.03461095898460442	[16]	[11]	0	hSpCas9	negative selection	11471061
78045482	78045505	X	-	28162770	MOLM13	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	-1.5263742489062766	[250]	[62]	-6	hSpCas9	negative selection	11471062
77988359	77988382	X	-	28162770	MOLM13	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	-0.2169534815454948	[298]	[185]	-1	hSpCas9	negative selection	11471063
77989623	77989646	X	+	28162770	HEL	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.5220573495778938	[161]	[148]	4	hSpCas9	negative selection	11640420
77989915	77989938	X	+	28162770	HEL	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.22071490240540637	[137]	[102]	1	hSpCas9	negative selection	11640421
77998566	77998589	X	+	28162770	HEL	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	0.28428486108788054	[49]	[38]	2	hSpCas9	negative selection	11640422
78011527	78011550	X	-	28162770	HEL	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	-0.13931465169438745	[324]	[188]	-1	hSpCas9	negative selection	11640423
78012967	78012990	X	-	28162770	HEL	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.5242973747028177	[405]	[373]	4	hSpCas9	negative selection	11640424
78013091	78013114	X	+	28162770	HEL	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.4554602638077764	[114]	[100]	4	hSpCas9	negative selection	11640425
78033604	78033627	X	+	28162770	HEL	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	0.15241320541727588	[294]	[209]	1	hSpCas9	negative selection	11640426
78042656	78042679	X	+	28162770	HEL	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-0.6202955738334373	[23]	[9]	-4	hSpCas9	negative selection	11640427
78045482	78045505	X	-	28162770	HEL	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	-0.23723046429287298	[218]	[118]	-2	hSpCas9	negative selection	11640428
77988359	77988382	X	-	28162770	HEL	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.5609956825588205	[235]	[222]	5	hSpCas9	negative selection	11640429
77989623	77989646	X	+	28162770	MV411	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.37029429856830876	[134]	[146]	3	hSpCas9	negative selection	11809786
77989915	77989938	X	+	28162770	MV411	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	-0.8680396666371607	[129]	[59]	-5	hSpCas9	negative selection	11809787
77998566	77998589	X	+	28162770	MV411	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	-0.15111182570749948	[28]	[21]	-1	hSpCas9	negative selection	11809788
78011527	78011550	X	-	28162770	MV411	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.6316690032804446	[212]	[277]	6	hSpCas9	negative selection	11809789
78012967	78012990	X	-	28162770	MV411	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.8194221975057214	[334]	[497]	7	hSpCas9	negative selection	11809790
78013091	78013114	X	+	28162770	MV411	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.35569044143479867	[76]	[82]	3	hSpCas9	negative selection	11809791
78033604	78033627	X	+	28162770	MV411	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	0.12714331706506346	[199]	[183]	1	hSpCas9	negative selection	11809792
78042656	78042679	X	+	28162770	MV411	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-4.00048996266081	[18]	[0]	-9	hSpCas9	negative selection	11809793
78045482	78045505	X	-	28162770	MV411	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	-0.38332863955150576	[143]	[92]	-3	hSpCas9	negative selection	11809794
77988359	77988382	X	-	28162770	MV411	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	1.102828170078669	[172]	[312]	8	hSpCas9	negative selection	11809795
77989623	77989646	X	+	28162770	MONOMAC1	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	-0.2463645594231221	[118]	[114]	-2	hSpCas9	negative selection	11979152
77989915	77989938	X	+	28162770	MONOMAC1	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	1.0560820899091574	[72]	[173]	8	hSpCas9	negative selection	11979153
77998566	77998589	X	+	28162770	MONOMAC1	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	-0.4085409522532655	[21]	[18]	-4	hSpCas9	negative selection	11979154
78011527	78011550	X	-	28162770	MONOMAC1	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.22425964269097254	[114]	[153]	2	hSpCas9	negative selection	11979155
78012967	78012990	X	-	28162770	MONOMAC1	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.04175001252756272	[249]	[294]	0	hSpCas9	negative selection	11979156
78013091	78013114	X	+	28162770	MONOMAC1	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	-0.518964941946916	[59]	[47]	-4	hSpCas9	negative selection	11979157
78033604	78033627	X	+	28162770	MONOMAC1	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	0.579895154424297	[177]	[304]	5	hSpCas9	negative selection	11979158
78042656	78042679	X	+	28162770	MONOMAC1	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	0.9404666766903813	[9]	[21]	8	hSpCas9	negative selection	11979159
78045482	78045505	X	-	28162770	MONOMAC1	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	0.7397693264532523	[104]	[200]	7	hSpCas9	negative selection	11979160
77988359	77988382	X	-	28162770	MONOMAC1	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	-0.028437243083808895	[120]	[135]	0	hSpCas9	negative selection	11979161
77989623	77989646	X	+	28162770	OCIAML2	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.737478370088039	[28]	[267]	7	hSpCas9	negative selection	12148518
77989915	77989938	X	+	28162770	OCIAML2	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	-0.13564557752935258	[21]	[110]	-1	hSpCas9	negative selection	12148519
77998566	77998589	X	+	28162770	OCIAML2	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	-1.108059745857453	[13]	[35]	-6	hSpCas9	negative selection	12148520
78011527	78011550	X	-	28162770	OCIAML2	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.6030798609408482	[30]	[260]	6	hSpCas9	negative selection	12148521
78012967	78012990	X	-	28162770	OCIAML2	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.4738750621661354	[52]	[407]	4	hSpCas9	negative selection	12148522
78013091	78013114	X	+	28162770	OCIAML2	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.20396988796367124	[25]	[165]	2	hSpCas9	negative selection	12148523
78033604	78033627	X	+	28162770	OCIAML2	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	0.09327105995116519	[45]	[271]	0	hSpCas9	negative selection	12148524
78042656	78042679	X	+	28162770	OCIAML2	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	1.114332675478995	[3]	[47]	9	hSpCas9	negative selection	12148525
78045482	78045505	X	-	28162770	OCIAML2	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	1.1538610396656324	[17]	[221]	9	hSpCas9	negative selection	12148526
77988359	77988382	X	-	28162770	OCIAML2	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.19612676664264234	[39]	[253]	1	hSpCas9	negative selection	12148527
77989623	77989646	X	+	28162770	OCIAML3	viability	CAATAGAGGCTGTATCACCGGGG	ATP7A	ENSG00000165240	0.10879135069085126	[46]	[152]	1	hSpCas9	negative selection	12317884
77989915	77989938	X	+	28162770	OCIAML3	viability	GAGAGGAGCAATAGAAGACATGG	ATP7A	ENSG00000165240	0.7618677864865367	[41]	[214]	6	hSpCas9	negative selection	12317885
77998566	77998589	X	+	28162770	OCIAML3	viability	GACACCAGTTCAAGACAAGGAGG	ATP7A	ENSG00000165240	2.485719552146571	[10]	[185]	9	hSpCas9	negative selection	12317886
78011527	78011550	X	-	28162770	OCIAML3	viability	GGTGAAGAGTTGCAAAGTGGTGG	ATP7A	ENSG00000165240	0.552833748005108	[41]	[185]	5	hSpCas9	negative selection	12317887
78012967	78012990	X	-	28162770	OCIAML3	viability	AGAGTAGGCAAATGCAATGGTGG	ATP7A	ENSG00000165240	0.5250450313196	[92]	[403]	5	hSpCas9	negative selection	12317888
78013091	78013114	X	+	28162770	OCIAML3	viability	ATGGCTGGAACATATAGCAAAGG	ATP7A	ENSG00000165240	0.3494088313094693	[25]	[99]	3	hSpCas9	negative selection	12317889
78033604	78033627	X	+	28162770	OCIAML3	viability	GGAGCTGGACACTGAAACCTTGG	ATP7A	ENSG00000165240	-0.08381290800497909	[65]	[187]	0	hSpCas9	negative selection	12317890
78042656	78042679	X	+	28162770	OCIAML3	viability	GGAGGGGAAACGGGTAGCAATGG	ATP7A	ENSG00000165240	-0.009045139603006902	[1]	[5]	0	hSpCas9	negative selection	12317891
78045482	78045505	X	-	28162770	OCIAML3	viability	GGGCTGCAAAACCAAACCAATGG	ATP7A	ENSG00000165240	0.1086064490512661	[50]	[165]	1	hSpCas9	negative selection	12317892
77988359	77988382	X	-	28162770	OCIAML3	viability	GTGTCAGTTAAAACAGGGAGAGG	ATP7A	ENSG00000165240	0.45208877426529104	[76]	[317]	4	hSpCas9	negative selection	12317893