Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:545
• Symbol:ATR
• Description:ATR serine/threonine kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/ATR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
142566200	142566223	3	+	26472758	Jiyoye	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.128877518734336	[115]	[9]	-9	hSpCas9	negative selection	12885
142519735	142519758	3	-	26472758	Jiyoye	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-1.954012143828716	[148]	[28]	-8	hSpCas9	negative selection	12886
142561244	142561267	3	-	26472758	Jiyoye	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	-0.11791566323788438	[294]	[204]	-1	hSpCas9	negative selection	12887
142519719	142519742	3	-	26472758	Jiyoye	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-1.480349889235714	[110]	[29]	-7	hSpCas9	negative selection	12888
142508031	142508054	3	+	26472758	Jiyoye	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-1.0421320198577166	[70]	[25]	-6	hSpCas9	negative selection	12889
142493232	142493255	3	-	26472758	Jiyoye	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.8698711147006448	[268]	[110]	-6	hSpCas9	negative selection	12890
142461978	142462001	3	-	26472758	Jiyoye	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-2.507094744468243	[97]	[12]	-9	hSpCas9	negative selection	12891
142563039	142563062	3	+	26472758	Jiyoye	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	0.10949483286518834	[117]	[95]	0	hSpCas9	negative selection	12892
142562231	142562254	3	-	26472758	Jiyoye	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-2.3948852408822177	[271]	[38]	-8	hSpCas9	negative selection	12893
142559284	142559307	3	-	26472758	Jiyoye	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-2.3152906429652176	[65]	[9]	-8	hSpCas9	negative selection	12894
142566200	142566223	3	+	26472758	KBM7	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.322357946032207	[402,298]	[28,4]	-9	hSpCas9	negative selection	204003
142519735	142519758	3	-	26472758	KBM7	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.8332964397646597	[626,429]	[99,170]	-6	hSpCas9	negative selection	204004
142561244	142561267	3	-	26472758	KBM7	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	0.006498513825103025	[982,697]	[485,307]	0	hSpCas9	negative selection	204005
142519719	142519742	3	-	26472758	KBM7	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-3.4692753921521953	[500,283]	[29,3]	-9	hSpCas9	negative selection	204006
142508031	142508054	3	+	26472758	KBM7	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-2.2257644802603416	[599,365]	[45,48]	-8	hSpCas9	negative selection	204007
142493232	142493255	3	-	26472758	KBM7	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.2808298921018739	[727,545]	[354,144]	-3	hSpCas9	negative selection	204008
142461978	142462001	3	-	26472758	KBM7	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-2.601497300259645	[848,721]	[38,79]	-9	hSpCas9	negative selection	204009
142563039	142563062	3	+	26472758	KBM7	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	0.4820438170350888	[492,455]	[398,233]	5	hSpCas9	negative selection	204010
142562231	142562254	3	-	26472758	KBM7	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-2.518893932079122	[1342,1196]	[111,96]	-9	hSpCas9	negative selection	204011
142559284	142559307	3	-	26472758	KBM7	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-4.0942567340986225	[455,473]	[14,10]	-9	hSpCas9	negative selection	204012
142566200	142566223	3	+	26472758	Raji	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.7605129286190555	[72]	[4]	-8	hSpCas9	negative selection	395121
142519735	142519758	3	-	26472758	Raji	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-1.2655685625382296	[258]	[24]	-7	hSpCas9	negative selection	395122
142561244	142561267	3	-	26472758	Raji	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	0.22474048601175822	[353]	[95]	2	hSpCas9	negative selection	395123
142519719	142519742	3	-	26472758	Raji	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-0.2062769435301624	[173]	[34]	-2	hSpCas9	negative selection	395124
142508031	142508054	3	+	26472758	Raji	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-2.4317752757344318	[185]	[7]	-9	hSpCas9	negative selection	395125
142493232	142493255	3	-	26472758	Raji	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.965244264713798	[386]	[45]	-6	hSpCas9	negative selection	395126
142461978	142462001	3	-	26472758	Raji	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-1.3844695609560755	[359]	[31]	-7	hSpCas9	negative selection	395127
142563039	142563062	3	+	26472758	Raji	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	-0.1727243838191358	[169]	[34]	-1	hSpCas9	negative selection	395128
142562231	142562254	3	-	26472758	Raji	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-3.0477009747578117	[676]	[18]	-9	hSpCas9	negative selection	395129
142559284	142559307	3	-	26472758	Raji	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-3.739897571096764	[402]	[6]	-9	hSpCas9	negative selection	395130
142566200	142566223	3	+	26472758	K562	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.6511120057775237	[252]	[33]	-8	hSpCas9	negative selection	586239
142519735	142519758	3	-	26472758	K562	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.42039708074392396	[324]	[204]	-3	hSpCas9	negative selection	586240
142561244	142561267	3	-	26472758	K562	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	0.3295581801408578	[657]	[697]	2	hSpCas9	negative selection	586241
142519719	142519742	3	-	26472758	K562	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-4.085970945969112	[341]	[16]	-9	hSpCas9	negative selection	586242
142508031	142508054	3	+	26472758	K562	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-2.2306661552823357	[277]	[49]	-7	hSpCas9	negative selection	586243
142493232	142493255	3	-	26472758	K562	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.7907707007958532	[497]	[242]	-5	hSpCas9	negative selection	586244
142461978	142462001	3	-	26472758	K562	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-2.3353071246885624	[549]	[91]	-8	hSpCas9	negative selection	586245
142563039	142563062	3	+	26472758	K562	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	0.4493074013635897	[307]	[354]	3	hSpCas9	negative selection	586246
142562231	142562254	3	-	26472758	K562	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-2.191166149016483	[989]	[182]	-7	hSpCas9	negative selection	586247
142559284	142559307	3	-	26472758	K562	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-7.858869080745575	[549]	[1]	-9	hSpCas9	negative selection	586248
142519717	142519740	3	+	26627737	DLD1	viability	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	0.7732849271086291	[484]	[424,267,107]	7	hSpCas9	negative selection	819863
142553215	142553238	3	+	26627737	DLD1	viability	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-3.1841354313600796	[159]	[14,0,0]	-9	hSpCas9	negative selection	819864
142556487	142556510	3	-	26627737	DLD1	viability	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	-0.3615860776887115	[387]	[77,105,98]	-4	hSpCas9	negative selection	819865
142559305	142559328	3	-	26627737	DLD1	viability	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.4610524020224268	[271]	[109,10,61]	-5	hSpCas9	negative selection	819866
142562882	142562905	3	-	26627737	DLD1	viability	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-4.853213611125723	[215]	[3,0,1]	-9	hSpCas9	negative selection	819867
142566200	142566223	3	+	26627737	DLD1	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-4.547526186334777	[605]	[14,0,7]	-9	hSpCas9	negative selection	819868
142519717	142519740	3	+	26627737	GBM cells	viability after 5 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.4691261448559888	[301]	[138,94]	-6	hSpCas9	negative selection	902178
142553215	142553238	3	+	26627737	GBM cells	viability after 5 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	0.32954822921554805	[68]	[48,43]	5	hSpCas9	negative selection	902179
142556487	142556510	3	-	26627737	GBM cells	viability after 5 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.43259587066314836	[209]	[166,136]	6	hSpCas9	negative selection	902180
142559305	142559328	3	-	26627737	GBM cells	viability after 5 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.11221842339417432	[181]	[113,96]	1	hSpCas9	negative selection	902181
142562882	142562905	3	-	26627737	GBM cells	viability after 5 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-1.5446927765899294	[203]	[15,58]	-9	hSpCas9	negative selection	902182
142566200	142566223	3	+	26627737	GBM cells	viability after 5 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.5690725043421176	[295]	[52,53]	-9	hSpCas9	negative selection	902183
142519717	142519740	3	+	26627737	GBM cells	viability after 13 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.14928729556909895	[301]	[128,162]	-2	hSpCas9	negative selection	984493
142553215	142553238	3	+	26627737	GBM cells	viability after 13 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-1.0238653275174423	[68]	[13,21]	-8	hSpCas9	negative selection	984494
142556487	142556510	3	-	26627737	GBM cells	viability after 13 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.7058753151330652	[209]	[240,140]	8	hSpCas9	negative selection	984495
142559305	142559328	3	-	26627737	GBM cells	viability after 13 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.16326666163291192	[181]	[98,119]	2	hSpCas9	negative selection	984496
142562882	142562905	3	-	26627737	GBM cells	viability after 13 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-1.6233469113761314	[203]	[25,43]	-9	hSpCas9	negative selection	984497
142566200	142566223	3	+	26627737	GBM cells	viability after 13 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.5760030975922823	[295]	[65,43]	-9	hSpCas9	negative selection	984498
142519717	142519740	3	+	26627737	GBM cells	viability after 21 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	0.5321266197294326	[301]	[242,231]	5	hSpCas9	negative selection	1066808
142553215	142553238	3	+	26627737	GBM cells	viability after 21 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-5.228291157162511	[68]	[0,0]	-9	hSpCas9	negative selection	1066809
142556487	142556510	3	-	26627737	GBM cells	viability after 21 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.7697789498584351	[209]	[193,194]	7	hSpCas9	negative selection	1066810
142559305	142559328	3	-	26627737	GBM cells	viability after 21 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.5556604834727321	[181]	[160,130]	5	hSpCas9	negative selection	1066811
142562882	142562905	3	-	26627737	GBM cells	viability after 21 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-5.509258079084338	[203]	[3,0]	-9	hSpCas9	negative selection	1066812
142566200	142566223	3	+	26627737	GBM cells	viability after 21 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.3078390485369136	[295]	[32,31]	-9	hSpCas9	negative selection	1066813
142519717	142519740	3	+	26627737	RPE1	viability after 9 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	0.6258625829826444	[1110]	[465,627]	4	hSpCas9	negative selection	1149123
142553215	142553238	3	+	26627737	RPE1	viability after 9 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-5.589777806609798	[220]	[0,1]	-9	hSpCas9	negative selection	1149124
142556487	142556510	3	-	26627737	RPE1	viability after 9 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	2.0382761659348994	[373]	[390,596]	9	hSpCas9	negative selection	1149125
142559305	142559328	3	-	26627737	RPE1	viability after 9 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-1.5215417552985635	[744]	[75,87]	-8	hSpCas9	negative selection	1149126
142562882	142562905	3	-	26627737	RPE1	viability after 9 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-8.398694932437685	[1077]	[0,0]	-9	hSpCas9	negative selection	1149127
142566200	142566223	3	+	26627737	RPE1	viability after 9 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-4.000491668329949	[943]	[0,40]	-9	hSpCas9	negative selection	1149128
142519717	142519740	3	+	26627737	RPE1	viability after 12 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.052752138941904225	[1110]	[415,151]	0	hSpCas9	negative selection	1231438
142553215	142553238	3	+	26627737	RPE1	viability after 12 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-5.891791147718294	[220]	[0,0]	-9	hSpCas9	negative selection	1231439
142556487	142556510	3	-	26627737	RPE1	viability after 12 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	1.3059042470344844	[373]	[177,322]	7	hSpCas9	negative selection	1231440
142559305	142559328	3	-	26627737	RPE1	viability after 12 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.8790716480580125	[744]	[68,150]	-6	hSpCas9	negative selection	1231441
142562882	142562905	3	-	26627737	RPE1	viability after 12 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-3.9696911660318266	[1077]	[34,0]	-9	hSpCas9	negative selection	1231442
142566200	142566223	3	+	26627737	RPE1	viability after 12 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-4.101794184318735	[943]	[6,22]	-9	hSpCas9	negative selection	1231443
142519717	142519740	3	+	26627737	RPE1	viability after 15 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.7995148833859931	[1110]	[204,156]	-5	hSpCas9	negative selection	1313753
142553215	142553238	3	+	26627737	RPE1	viability after 15 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-2.346522913239644	[220]	[23,0]	-8	hSpCas9	negative selection	1313754
142556487	142556510	3	-	26627737	RPE1	viability after 15 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.5194711679869446	[373]	[114,186]	3	hSpCas9	negative selection	1313755
142559305	142559328	3	-	26627737	RPE1	viability after 15 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-1.7296353842977332	[744]	[60,65]	-8	hSpCas9	negative selection	1313756
142562882	142562905	3	-	26627737	RPE1	viability after 15 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-3.7540261855922616	[1077]	[44,0]	-9	hSpCas9	negative selection	1313757
142566200	142566223	3	+	26627737	RPE1	viability after 15 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.363596352925948	[943]	[0,49]	-9	hSpCas9	negative selection	1313758
142519717	142519740	3	+	26627737	RPE1	viability after 18 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.03955591569891992	[1110]	[399,175]	0	hSpCas9	negative selection	1396068
142553215	142553238	3	+	26627737	RPE1	viability after 18 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-5.329314641065256	[220]	[0,1]	-9	hSpCas9	negative selection	1396069
142556487	142556510	3	-	26627737	RPE1	viability after 18 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	1.0583536249791445	[373]	[142,281]	6	hSpCas9	negative selection	1396070
142559305	142559328	3	-	26627737	RPE1	viability after 18 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.862690697031301	[744]	[126,92]	-5	hSpCas9	negative selection	1396071
142562882	142562905	3	-	26627737	RPE1	viability after 18 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-4.972619499164233	[1077]	[16,0]	-9	hSpCas9	negative selection	1396072
142566200	142566223	3	+	26627737	RPE1	viability after 18 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.682889715827441	[943]	[0,80]	-9	hSpCas9	negative selection	1396073
142519717	142519740	3	+	26627737	HeLa	viability after 8 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.3284622041495019	[564]	[315,148,151]	-3	hSpCas9	negative selection	1478383
142553215	142553238	3	+	26627737	HeLa	viability after 8 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	0.40619170466525345	[39]	[61,10,5]	4	hSpCas9	negative selection	1478384
142556487	142556510	3	-	26627737	HeLa	viability after 8 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.42072638351377045	[389]	[284,326,91]	4	hSpCas9	negative selection	1478385
142559305	142559328	3	-	26627737	HeLa	viability after 8 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.3601757804791481	[170]	[144,3,44]	-4	hSpCas9	negative selection	1478386
142562882	142562905	3	-	26627737	HeLa	viability after 8 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	1.2291972545181822	[112]	[149,110,93]	8	hSpCas9	negative selection	1478387
142566200	142566223	3	+	26627737	HeLa	viability after 8 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.5422798866217264	[575]	[36,80,11]	-9	hSpCas9	negative selection	1478388
142519717	142519740	3	+	26627737	HeLa	viability after 12 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.7448302289413478	[564]	[10,207,187]	-6	hSpCas9	negative selection	1560698
142553215	142553238	3	+	26627737	HeLa	viability after 12 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-1.3770349529985904	[39]	[17,0,0]	-8	hSpCas9	negative selection	1560699
142556487	142556510	3	-	26627737	HeLa	viability after 12 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.7494182227974878	[389]	[292,218,306]	6	hSpCas9	negative selection	1560700
142559305	142559328	3	-	26627737	HeLa	viability after 12 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.21647132012999803	[170]	[59,97,85]	2	hSpCas9	negative selection	1560701
142562882	142562905	3	-	26627737	HeLa	viability after 12 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-0.556613830729318	[112]	[0,53,36]	-5	hSpCas9	negative selection	1560702
142566200	142566223	3	+	26627737	HeLa	viability after 12 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-4.134076235599711	[575]	[2,16,19]	-9	hSpCas9	negative selection	1560703
142519717	142519740	3	+	26627737	HeLa	viability after 15 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	0.007537349839656038	[564]	[147,275,273]	0	hSpCas9	negative selection	1643013
142553215	142553238	3	+	26627737	HeLa	viability after 15 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-4.025394982579357	[39]	[0,0,0]	-9	hSpCas9	negative selection	1643014
142556487	142556510	3	-	26627737	HeLa	viability after 15 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	-0.5094638380244602	[389]	[184,44,102]	-4	hSpCas9	negative selection	1643015
142559305	142559328	3	-	26627737	HeLa	viability after 15 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.038557116772081956	[170]	[39,55,110]	0	hSpCas9	negative selection	1643016
142562882	142562905	3	-	26627737	HeLa	viability after 15 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	0.5326687278080307	[112]	[72,102,19]	4	hSpCas9	negative selection	1643017
142566200	142566223	3	+	26627737	HeLa	viability after 15 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.7573357019109186	[575]	[54,62,91]	-9	hSpCas9	negative selection	1643018
142519717	142519740	3	+	26627737	HeLa	viability after 18 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	0.023071087013544656	[564]	[98,234,273]	0	hSpCas9	negative selection	1725328
142553215	142553238	3	+	26627737	HeLa	viability after 18 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-3.71518933092549	[39]	[0,0,0]	-9	hSpCas9	negative selection	1725329
142556487	142556510	3	-	26627737	HeLa	viability after 18 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	-0.5372466149585912	[389]	[120,35,102]	-5	hSpCas9	negative selection	1725330
142559305	142559328	3	-	26627737	HeLa	viability after 18 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.04221939076667791	[170]	[25,46,110]	0	hSpCas9	negative selection	1725331
142562882	142562905	3	-	26627737	HeLa	viability after 18 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	0.406860104899778	[112]	[39,82,19]	3	hSpCas9	negative selection	1725332
142566200	142566223	3	+	26627737	HeLa	viability after 18 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.8122137853203548	[575]	[31,51,91]	-9	hSpCas9	negative selection	1725333
142519717	142519740	3	+	26627737	HCT116	viability after 6 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	0.9842716353386357	[740]	[301,190]	5	hSpCas9	negative selection	1807643
142553215	142553238	3	+	26627737	HCT116	viability after 6 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	0.14235401035715523	[130]	[43,10]	0	hSpCas9	negative selection	1807644
142556487	142556510	3	-	26627737	HCT116	viability after 6 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.7887906907350675	[922]	[289,228]	4	hSpCas9	negative selection	1807645
142559305	142559328	3	-	26627737	HCT116	viability after 6 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.8201877528656792	[392]	[266,21]	4	hSpCas9	negative selection	1807646
142562882	142562905	3	-	26627737	HCT116	viability after 6 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-0.6346355482716182	[259]	[64,4]	-4	hSpCas9	negative selection	1807647
142566200	142566223	3	+	26627737	HCT116	viability after 6 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	0.009829642781015058	[882]	[229,89]	0	hSpCas9	negative selection	1807648
142519717	142519740	3	+	26627737	HCT116	viability after 8 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	1.7575526673047182	[110]	[242,164,212]	9	hSpCas9	negative selection	1889958
142553215	142553238	3	+	26627737	HCT116	viability after 8 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-0.4590852637841778	[99]	[18,70,29]	-5	hSpCas9	negative selection	1889959
142556487	142556510	3	-	26627737	HCT116	viability after 8 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	2.0861230017721057	[115]	[226,362,223]	9	hSpCas9	negative selection	1889960
142559305	142559328	3	-	26627737	HCT116	viability after 8 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.21986366349476055	[222]	[103,129,193]	2	hSpCas9	negative selection	1889961
142562882	142562905	3	-	26627737	HCT116	viability after 8 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-0.8994514489111933	[185]	[30,44,87]	-8	hSpCas9	negative selection	1889962
142566200	142566223	3	+	26627737	HCT116	viability after 8 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.6250405915532755	[250]	[26,2,3]	-9	hSpCas9	negative selection	1889963
142519717	142519740	3	+	26627737	HCT116	viability after 9 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.4452075303058472	[740]	[270,45]	-3	hSpCas9	negative selection	1972273
142553215	142553238	3	+	26627737	HCT116	viability after 9 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-3.708529935733322	[130]	[0,3]	-9	hSpCas9	negative selection	1972274
142556487	142556510	3	-	26627737	HCT116	viability after 9 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	-0.39774664133025417	[922]	[90,262]	-3	hSpCas9	negative selection	1972275
142559305	142559328	3	-	26627737	HCT116	viability after 9 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-1.7512552347311567	[392]	[19,39]	-8	hSpCas9	negative selection	1972276
142562882	142562905	3	-	26627737	HCT116	viability after 9 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-5.4771656403883675	[259]	[0,1]	-9	hSpCas9	negative selection	1972277
142566200	142566223	3	+	26627737	HCT116	viability after 9 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-0.4161730763828115	[882]	[398,0]	-3	hSpCas9	negative selection	1972278
142519717	142519740	3	+	26627737	HCT116	viability after 12 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	1.4843923277905617	[110]	[171,126,188]	9	hSpCas9	negative selection	2054588
142553215	142553238	3	+	26627737	HCT116	viability after 12 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-1.962662482721657	[99]	[18,14,5]	-9	hSpCas9	negative selection	2054589
142556487	142556510	3	-	26627737	HCT116	viability after 12 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	1.8989176713913982	[115]	[163,243,279]	9	hSpCas9	negative selection	2054590
142559305	142559328	3	-	26627737	HCT116	viability after 12 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.032411041514256556	[222]	[84,181,80]	0	hSpCas9	negative selection	2054591
142562882	142562905	3	-	26627737	HCT116	viability after 12 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-2.701348138015789	[185]	[15,14,13]	-9	hSpCas9	negative selection	2054592
142566200	142566223	3	+	26627737	HCT116	viability after 12 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-5.257194945414961	[250]	[6,1,0]	-9	hSpCas9	negative selection	2054593
142519717	142519740	3	+	26627737	HCT116	viability after 15 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	1.8822755957680157	[110]	[161,204,327]	9	hSpCas9	negative selection	2136903
142553215	142553238	3	+	26627737	HCT116	viability after 15 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-1.9631055718216863	[99]	[6,0,34]	-9	hSpCas9	negative selection	2136904
142556487	142556510	3	-	26627737	HCT116	viability after 15 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	1.6378021882793514	[115]	[182,313,122]	9	hSpCas9	negative selection	2136905
142559305	142559328	3	-	26627737	HCT116	viability after 15 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.7125374063588877	[222]	[40,115,72]	-6	hSpCas9	negative selection	2136906
142562882	142562905	3	-	26627737	HCT116	viability after 15 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-3.0375669196546684	[185]	[20,5,12]	-9	hSpCas9	negative selection	2136907
142566200	142566223	3	+	26627737	HCT116	viability after 15 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-5.124833084218517	[250]	[8,0,2]	-9	hSpCas9	negative selection	2136908
142519717	142519740	3	+	26627737	HCT116	viability after 18 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	1.9258464377514748	[110]	[249,130,236]	9	hSpCas9	negative selection	2219218
142553215	142553238	3	+	26627737	HCT116	viability after 18 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-3.3017868926530367	[99]	[0,3,9]	-9	hSpCas9	negative selection	2219219
142556487	142556510	3	-	26627737	HCT116	viability after 18 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	1.539311139961064	[115]	[163,213,104]	9	hSpCas9	negative selection	2219220
142559305	142559328	3	-	26627737	HCT116	viability after 18 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.16809100598691118	[222]	[24,140,119]	-1	hSpCas9	negative selection	2219221
142562882	142562905	3	-	26627737	HCT116	viability after 18 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-4.6230824811879705	[185]	[8,0,0]	-9	hSpCas9	negative selection	2219222
142566200	142566223	3	+	26627737	HCT116	viability after 18 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-5.067496546814453	[250]	[6,0,2]	-9	hSpCas9	negative selection	2219223
142566175	142566198	3	+	24336569	HL60	viability	GGGAGGATTTCATGATATGCTGG	ATR	ENSG00000175054	0.17858644676607627	[604]	[1448]	1	hSpCas9	negative selection	2249141
142566197	142566220	3	+	24336569	HL60	viability	GATGAAATCAAGCAACATCACGG	ATR	ENSG00000175054	0.33466726104285327	[823]	[2198]	3	hSpCas9	negative selection	2249142
142566204	142566227	3	+	24336569	HL60	viability	TCAAGCAACATCACGGAGGTTGG	ATR	ENSG00000175054	0.38858750065442965	[282]	[783]	3	hSpCas9	negative selection	2249143
142568085	142568108	3	-	24336569	HL60	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.2485065935380873	[374]	[667]	-2	hSpCas9	negative selection	2249144
142568095	142568118	3	+	24336569	HL60	viability	AATTGACACAGAATTTGTCTTGG	ATR	ENSG00000175054	0.14003583998568458	[692]	[1615]	1	hSpCas9	negative selection	2249145
142568125	142568148	3	+	24336569	HL60	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	0.15800183406649293	[323]	[764]	1	hSpCas9	negative selection	2249146
142568130	142568153	3	+	24336569	HL60	viability	TGTATTATATTCCTCTGGTGTGG	ATR	ENSG00000175054	-0.279403478240805	[233]	[407]	-2	hSpCas9	negative selection	2249147
142578641	142578664	3	+	24336569	HL60	viability	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	1.6323075477470772	[115]	[760]	9	hSpCas9	negative selection	2249148
142578646	142578669	3	+	24336569	HL60	viability	CTGCCCAGCTCCCGCAGGGCGGG	ATR	ENSG00000175054	1.5117095494115003	[291]	[1761]	8	hSpCas9	negative selection	2249149
142578668	142578691	3	+	24336569	HL60	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.5010029921426808	[748]	[1119]	-4	hSpCas9	negative selection	2249150
142566175	142566198	3	+	24336569	KBM7	viability	GGGAGGATTTCATGATATGCTGG	ATR	ENSG00000175054	-0.527527352865125	[370]	[701]	-4	hSpCas9	negative selection	2316318
142566197	142566220	3	+	24336569	KBM7	viability	GATGAAATCAAGCAACATCACGG	ATR	ENSG00000175054	-1.8588151256678702	[1136]	[854]	-8	hSpCas9	negative selection	2316319
142566204	142566227	3	+	24336569	KBM7	viability	TCAAGCAACATCACGGAGGTTGG	ATR	ENSG00000175054	0.14728829979013858	[628]	[1899]	1	hSpCas9	negative selection	2316320
142568085	142568108	3	-	24336569	KBM7	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.8430979643540402	[195]	[958]	7	hSpCas9	negative selection	2316321
142568095	142568118	3	+	24336569	KBM7	viability	AATTGACACAGAATTTGTCTTGG	ATR	ENSG00000175054	0.9327911708411414	[536]	[2795]	7	hSpCas9	negative selection	2316322
142568125	142568148	3	+	24336569	KBM7	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.7650307302275592	[361]	[580]	-5	hSpCas9	negative selection	2316323
142568130	142568153	3	+	24336569	KBM7	viability	TGTATTATATTCCTCTGGTGTGG	ATR	ENSG00000175054	-7.981557768551233	[277]	[2]	-9	hSpCas9	negative selection	2316324
142578641	142578664	3	+	24336569	KBM7	viability	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-2.959872629571806	[270]	[94]	-9	hSpCas9	negative selection	2316325
142578646	142578669	3	+	24336569	KBM7	viability	CTGCCCAGCTCCCGCAGGGCGGG	ATR	ENSG00000175054	1.3357968625742815	[207]	[1431]	9	hSpCas9	negative selection	2316326
142578668	142578691	3	+	24336569	KBM7	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-3.769507291436245	[499]	[99]	-9	hSpCas9	negative selection	2316327
142570424	142570447	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAATGG	ATR	ENSG00000175054	-0.29783996533031276	[705,290]	[109,64]	-1	dCas9-VP64	positive selection	2393715
142550815	142550838	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGCTCTGTCACTCAGGCTGG	ATR	ENSG00000175054	-0.9680761470245136	[202,921]	[9,121]	-5	dCas9-VP64	positive selection	2407078
142508728	142508751	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCGTGTTAGCCGGG	ATR	ENSG00000175054	0.853016361217498	[78,47]	[31,16]	3	dCas9-VP64	positive selection	2418349
142473753	142473776	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGTTCAAGATCAGCCAGG	ATR	ENSG00000175054	1.0000949637067877	[26,25]	[19,2]	4	dCas9-VP64	positive selection	2426308
142509594	142509617	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCCCAGGCTGGAGTGCAGGGG	ATR	ENSG00000175054	1.5196799666234522	[9,52]	[2,38]	5	dCas9-VP64	positive selection	2457330
142572537	142572560	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAAGCAGTCTGCCCACCTTGG	ATR	ENSG00000175054	0.20576949065447114	[17,35]	[6,5]	1	dCas9-VP64	positive selection	2476398
142570424	142570447	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAATGG	ATR	ENSG00000175054	-0.2409913144319511	[429,255]	[120,70]	-2	dCas9-VP64	positive selection	2488970
142550815	142550838	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGCTCTGTCACTCAGGCTGG	ATR	ENSG00000175054	-0.6011121662635273	[131,74]	[29,13]	-6	dCas9-VP64	positive selection	2502333
142508728	142508751	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCGTGTTAGCCGGG	ATR	ENSG00000175054	1.9224239682243596	[76,41]	[141,10]	8	dCas9-VP64	positive selection	2513604
142473753	142473776	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGTTCAAGATCAGCCAGG	ATR	ENSG00000175054	-1.1816738048605875	[96,64]	[6,14]	-9	dCas9-VP64	positive selection	2521563
142509594	142509617	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCCCAGGCTGGAGTGCAGGGG	ATR	ENSG00000175054	-0.8181473823206423	[116,171]	[31,20]	-7	dCas9-VP64	positive selection	2552585
142572537	142572560	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAAGCAGTCTGCCCACCTTGG	ATR	ENSG00000175054	0.6530020702020014	[53,174]	[34,79]	5	dCas9-VP64	positive selection	2571653
142556456	142556479	3	-	27260157	DLD1	viability	GAGCTCCCATGAAGTAATCCGGG	ATR	ENSG00000175054	-3.92909479610515	[]	[]	-9	hSpCas9	negative selection	2574566
142568085	142568108	3	-	27260157	DLD1	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.347232128983145	[]	[]	-3	hSpCas9	negative selection	2574988
142562882	142562905	3	-	27260157	DLD1	viability	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-1.77405094075951	[]	[]	-8	hSpCas9	negative selection	2576497
142556438	142556461	3	+	27260157	DLD1	viability	ATCCACTAACACAACTAGCCCGG	ATR	ENSG00000175054	0.871274060105486	[]	[]	9	hSpCas9	negative selection	2583544
142559428	142559451	3	-	27260157	DLD1	viability	TTACTGCAGCCGTACTTTCAAGG	ATR	ENSG00000175054	-1.16675247940117	[]	[]	-7	hSpCas9	negative selection	2586855
142563075	142563098	3	-	27260157	DLD1	viability	GGATCATAACGAGACTTCTGCGG	ATR	ENSG00000175054	-2.7050020263413	[]	[]	-9	hSpCas9	negative selection	2604135
142578668	142578691	3	+	27260157	DLD1	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-1.38583474705866	[]	[]	-8	hSpCas9	negative selection	2609184
142568125	142568148	3	+	27260157	DLD1	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-1.73350344779549	[]	[]	-8	hSpCas9	negative selection	2611257
142562596	142562619	3	+	27260157	DLD1	viability	AAAGTGCTAGCTGGTTGTGCTGG	ATR	ENSG00000175054	-1.40563660851348	[]	[]	-8	hSpCas9	negative selection	2613906
142556450	142556473	3	+	27260157	DLD1	viability	AACTAGCCCGGATTACTTCATGG	ATR	ENSG00000175054	-2.54989699716944	[]	[]	-9	hSpCas9	negative selection	2615553
142566204	142566227	3	+	27260157	DLD1	viability	TCAAGCAACATCACGGAGGTTGG	ATR	ENSG00000175054	1.62177037733033	[]	[]	9	hSpCas9	negative selection	2617389
142566175	142566198	3	+	27260157	DLD1	viability	GGGAGGATTTCATGATATGCTGG	ATR	ENSG00000175054	-2.26683742107512	[]	[]	-9	hSpCas9	negative selection	2617729
142578646	142578669	3	+	27260157	DLD1	viability	CTGCCCAGCTCCCGCAGGGCGGG	ATR	ENSG00000175054	0.651031949143328	[]	[]	8	hSpCas9	negative selection	2618861
142566197	142566220	3	+	27260157	DLD1	viability	GATGAAATCAAGCAACATCACGG	ATR	ENSG00000175054	-3.29121769067544	[]	[]	-9	hSpCas9	negative selection	2621850
142578641	142578664	3	+	27260157	DLD1	viability	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-0.996376847275285	[]	[]	-7	hSpCas9	negative selection	2623846
142568130	142568153	3	+	27260157	DLD1	viability	TGTATTATATTCCTCTGGTGTGG	ATR	ENSG00000175054	-2.69488322308286	[]	[]	-9	hSpCas9	negative selection	2643259
142556487	142556510	3	-	27260157	DLD1	viability	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	-0.234083071131568	[]	[]	-2	hSpCas9	negative selection	2644472
142568095	142568118	3	+	27260157	DLD1	viability	AATTGACACAGAATTTGTCTTGG	ATR	ENSG00000175054	-1.02778164110793	[]	[]	-7	hSpCas9	negative selection	2646635
142558715	142558738	3	-	27260157	DLD1	viability	GTGGTATGCTCTCACTTCCATGG	ATR	ENSG00000175054	-1.73230939720268	[]	[]	-8	hSpCas9	negative selection	2648751
142556456	142556479	3	-	27260157	HT1080	viability	GAGCTCCCATGAAGTAATCCGGG	ATR	ENSG00000175054	-3.35486188511764	[]	[]	-9	hSpCas9	negative selection	2650696
142568085	142568108	3	-	27260157	HT1080	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.790915793878374	[]	[]	-8	hSpCas9	negative selection	2651118
142562882	142562905	3	-	27260157	HT1080	viability	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-1.34278505008175	[]	[]	-9	hSpCas9	negative selection	2652627
142556438	142556461	3	+	27260157	HT1080	viability	ATCCACTAACACAACTAGCCCGG	ATR	ENSG00000175054	1.542566202063	[]	[]	9	hSpCas9	negative selection	2659674
142559428	142559451	3	-	27260157	HT1080	viability	TTACTGCAGCCGTACTTTCAAGG	ATR	ENSG00000175054	-0.725168735105116	[]	[]	-8	hSpCas9	negative selection	2662985
142563075	142563098	3	-	27260157	HT1080	viability	GGATCATAACGAGACTTCTGCGG	ATR	ENSG00000175054	-1.49779080190955	[]	[]	-9	hSpCas9	negative selection	2680265
142578668	142578691	3	+	27260157	HT1080	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-1.28442570383743	[]	[]	-9	hSpCas9	negative selection	2685314
142568125	142568148	3	+	27260157	HT1080	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-1.47396232774277	[]	[]	-9	hSpCas9	negative selection	2687387
142562596	142562619	3	+	27260157	HT1080	viability	AAAGTGCTAGCTGGTTGTGCTGG	ATR	ENSG00000175054	-0.725079962769618	[]	[]	-8	hSpCas9	negative selection	2690036
142556450	142556473	3	+	27260157	HT1080	viability	AACTAGCCCGGATTACTTCATGG	ATR	ENSG00000175054	-1.82723397363806	[]	[]	-9	hSpCas9	negative selection	2691683
142566204	142566227	3	+	27260157	HT1080	viability	TCAAGCAACATCACGGAGGTTGG	ATR	ENSG00000175054	1.26646187433352	[]	[]	8	hSpCas9	negative selection	2693519
142566175	142566198	3	+	27260157	HT1080	viability	GGGAGGATTTCATGATATGCTGG	ATR	ENSG00000175054	-1.48607161469475	[]	[]	-9	hSpCas9	negative selection	2693859
142578646	142578669	3	+	27260157	HT1080	viability	CTGCCCAGCTCCCGCAGGGCGGG	ATR	ENSG00000175054	-0.196732843719536	[]	[]	0	hSpCas9	negative selection	2694991
142566197	142566220	3	+	27260157	HT1080	viability	GATGAAATCAAGCAACATCACGG	ATR	ENSG00000175054	-3.12321263292493	[]	[]	-9	hSpCas9	negative selection	2697980
142578641	142578664	3	+	27260157	HT1080	viability	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-1.96112605914923	[]	[]	-9	hSpCas9	negative selection	2699976
142568130	142568153	3	+	27260157	HT1080	viability	TGTATTATATTCCTCTGGTGTGG	ATR	ENSG00000175054	-2.50065152191539	[]	[]	-9	hSpCas9	negative selection	2719389
142556487	142556510	3	-	27260157	HT1080	viability	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	1.14439268779745	[]	[]	8	hSpCas9	negative selection	2720602
142568095	142568118	3	+	27260157	HT1080	viability	AATTGACACAGAATTTGTCTTGG	ATR	ENSG00000175054	-0.608576097940606	[]	[]	-8	hSpCas9	negative selection	2722765
142558715	142558738	3	-	27260157	HT1080	viability	GTGGTATGCTCTCACTTCCATGG	ATR	ENSG00000175054	-0.277872656050024	[]	[]	-4	hSpCas9	negative selection	2724881
142556456	142556479	3	-	27260157	MKN45	viability	GAGCTCCCATGAAGTAATCCGGG	ATR	ENSG00000175054	-1.69352121374759	[]	[]	-9	hSpCas9	negative selection	2726826
142568085	142568108	3	-	27260157	MKN45	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.268866813601038	[]	[]	5	hSpCas9	negative selection	2727248
142562882	142562905	3	-	27260157	MKN45	viability	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-1.71640181326976	[]	[]	-9	hSpCas9	negative selection	2728757
142556438	142556461	3	+	27260157	MKN45	viability	ATCCACTAACACAACTAGCCCGG	ATR	ENSG00000175054	1.6918628619724	[]	[]	9	hSpCas9	negative selection	2735804
142559428	142559451	3	-	27260157	MKN45	viability	TTACTGCAGCCGTACTTTCAAGG	ATR	ENSG00000175054	-1.20755483275615	[]	[]	-8	hSpCas9	negative selection	2739115
142563075	142563098	3	-	27260157	MKN45	viability	GGATCATAACGAGACTTCTGCGG	ATR	ENSG00000175054	-3.10040715192474	[]	[]	-9	hSpCas9	negative selection	2756395
142578668	142578691	3	+	27260157	MKN45	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-1.48732930533821	[]	[]	-8	hSpCas9	negative selection	2761444
142568125	142568148	3	+	27260157	MKN45	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-1.43395328487715	[]	[]	-8	hSpCas9	negative selection	2763517
142562596	142562619	3	+	27260157	MKN45	viability	AAAGTGCTAGCTGGTTGTGCTGG	ATR	ENSG00000175054	-0.550526704950349	[]	[]	-6	hSpCas9	negative selection	2766166
142556450	142556473	3	+	27260157	MKN45	viability	AACTAGCCCGGATTACTTCATGG	ATR	ENSG00000175054	-1.13017619172541	[]	[]	-8	hSpCas9	negative selection	2767813
142566204	142566227	3	+	27260157	MKN45	viability	TCAAGCAACATCACGGAGGTTGG	ATR	ENSG00000175054	2.13599979755353	[]	[]	9	hSpCas9	negative selection	2769649
142566175	142566198	3	+	27260157	MKN45	viability	GGGAGGATTTCATGATATGCTGG	ATR	ENSG00000175054	-1.68480493973666	[]	[]	-9	hSpCas9	negative selection	2769989
142578646	142578669	3	+	27260157	MKN45	viability	CTGCCCAGCTCCCGCAGGGCGGG	ATR	ENSG00000175054	0.994732353299673	[]	[]	8	hSpCas9	negative selection	2771121
142566197	142566220	3	+	27260157	MKN45	viability	GATGAAATCAAGCAACATCACGG	ATR	ENSG00000175054	-1.37856765699526	[]	[]	-8	hSpCas9	negative selection	2774110
142578641	142578664	3	+	27260157	MKN45	viability	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-2.044647275696	[]	[]	-9	hSpCas9	negative selection	2776106
142568130	142568153	3	+	27260157	MKN45	viability	TGTATTATATTCCTCTGGTGTGG	ATR	ENSG00000175054	-2.44647764252368	[]	[]	-9	hSpCas9	negative selection	2795519
142556487	142556510	3	-	27260157	MKN45	viability	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.298912077383854	[]	[]	5	hSpCas9	negative selection	2796732
142568095	142568118	3	+	27260157	MKN45	viability	AATTGACACAGAATTTGTCTTGG	ATR	ENSG00000175054	0.0454811470129867	[]	[]	0	hSpCas9	negative selection	2798895
142558715	142558738	3	-	27260157	MKN45	viability	GTGGTATGCTCTCACTTCCATGG	ATR	ENSG00000175054	-3.06637158681134	[]	[]	-9	hSpCas9	negative selection	2801011
142556456	142556479	3	-	27260157	RKO	viability	GAGCTCCCATGAAGTAATCCGGG	ATR	ENSG00000175054	-4.01305656948916	[]	[]	-9	hSpCas9	negative selection	2802956
142568085	142568108	3	-	27260157	RKO	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.769278412097467	[]	[]	-7	hSpCas9	negative selection	2803378
142562882	142562905	3	-	27260157	RKO	viability	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-2.57859563663359	[]	[]	-9	hSpCas9	negative selection	2804887
142556438	142556461	3	+	27260157	RKO	viability	ATCCACTAACACAACTAGCCCGG	ATR	ENSG00000175054	0.885363057080629	[]	[]	8	hSpCas9	negative selection	2811934
142559428	142559451	3	-	27260157	RKO	viability	TTACTGCAGCCGTACTTTCAAGG	ATR	ENSG00000175054	-3.05159864283286	[]	[]	-9	hSpCas9	negative selection	2815245
142563075	142563098	3	-	27260157	RKO	viability	GGATCATAACGAGACTTCTGCGG	ATR	ENSG00000175054	-3.82500013344244	[]	[]	-9	hSpCas9	negative selection	2832525
142578668	142578691	3	+	27260157	RKO	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-1.27956049098807	[]	[]	-8	hSpCas9	negative selection	2837574
142568125	142568148	3	+	27260157	RKO	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-1.88401912913222	[]	[]	-9	hSpCas9	negative selection	2839647
142562596	142562619	3	+	27260157	RKO	viability	AAAGTGCTAGCTGGTTGTGCTGG	ATR	ENSG00000175054	-1.33119389090223	[]	[]	-8	hSpCas9	negative selection	2842296
142556450	142556473	3	+	27260157	RKO	viability	AACTAGCCCGGATTACTTCATGG	ATR	ENSG00000175054	-2.01598292258023	[]	[]	-9	hSpCas9	negative selection	2843943
142566204	142566227	3	+	27260157	RKO	viability	TCAAGCAACATCACGGAGGTTGG	ATR	ENSG00000175054	1.41258822387354	[]	[]	9	hSpCas9	negative selection	2845779
142566175	142566198	3	+	27260157	RKO	viability	GGGAGGATTTCATGATATGCTGG	ATR	ENSG00000175054	-2.13851909460048	[]	[]	-9	hSpCas9	negative selection	2846119
142578646	142578669	3	+	27260157	RKO	viability	CTGCCCAGCTCCCGCAGGGCGGG	ATR	ENSG00000175054	-0.870704912682154	[]	[]	-8	hSpCas9	negative selection	2847251
142566197	142566220	3	+	27260157	RKO	viability	GATGAAATCAAGCAACATCACGG	ATR	ENSG00000175054	-2.61059937335858	[]	[]	-9	hSpCas9	negative selection	2850240
142578641	142578664	3	+	27260157	RKO	viability	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-2.54858975382244	[]	[]	-9	hSpCas9	negative selection	2852236
142568130	142568153	3	+	27260157	RKO	viability	TGTATTATATTCCTCTGGTGTGG	ATR	ENSG00000175054	-3.0452785209626	[]	[]	-9	hSpCas9	negative selection	2871649
142556487	142556510	3	-	27260157	RKO	viability	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	-0.35111812442148	[]	[]	-6	hSpCas9	negative selection	2872862
142568095	142568118	3	+	27260157	RKO	viability	AATTGACACAGAATTTGTCTTGG	ATR	ENSG00000175054	-1.02122252902669	[]	[]	-8	hSpCas9	negative selection	2875025
142558715	142558738	3	-	27260157	RKO	viability	GTGGTATGCTCTCACTTCCATGG	ATR	ENSG00000175054	-0.499797814590061	[]	[]	-6	hSpCas9	negative selection	2877141
142556456	142556479	3	-	27260157	SF268	viability	GAGCTCCCATGAAGTAATCCGGG	ATR	ENSG00000175054	-4.5431266193176	[]	[]	-9	hSpCas9	negative selection	2879086
142568085	142568108	3	-	27260157	SF268	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.00916611507031265	[]	[]	0	hSpCas9	negative selection	2879508
142562882	142562905	3	-	27260157	SF268	viability	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-2.72060874201241	[]	[]	-9	hSpCas9	negative selection	2881017
142556438	142556461	3	+	27260157	SF268	viability	ATCCACTAACACAACTAGCCCGG	ATR	ENSG00000175054	0.688684348185909	[]	[]	8	hSpCas9	negative selection	2888064
142559428	142559451	3	-	27260157	SF268	viability	TTACTGCAGCCGTACTTTCAAGG	ATR	ENSG00000175054	-1.88076599712269	[]	[]	-8	hSpCas9	negative selection	2891375
142563075	142563098	3	-	27260157	SF268	viability	GGATCATAACGAGACTTCTGCGG	ATR	ENSG00000175054	-3.24398748662886	[]	[]	-9	hSpCas9	negative selection	2908655
142578668	142578691	3	+	27260157	SF268	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-1.25940058006878	[]	[]	-7	hSpCas9	negative selection	2913704
142568125	142568148	3	+	27260157	SF268	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-2.59288874487009	[]	[]	-9	hSpCas9	negative selection	2915777
142562596	142562619	3	+	27260157	SF268	viability	AAAGTGCTAGCTGGTTGTGCTGG	ATR	ENSG00000175054	-2.27477069080804	[]	[]	-9	hSpCas9	negative selection	2918426
142556450	142556473	3	+	27260157	SF268	viability	AACTAGCCCGGATTACTTCATGG	ATR	ENSG00000175054	-2.67826445463474	[]	[]	-9	hSpCas9	negative selection	2920073
142566204	142566227	3	+	27260157	SF268	viability	TCAAGCAACATCACGGAGGTTGG	ATR	ENSG00000175054	1.71062311531817	[]	[]	9	hSpCas9	negative selection	2921909
142566175	142566198	3	+	27260157	SF268	viability	GGGAGGATTTCATGATATGCTGG	ATR	ENSG00000175054	-2.23276986972468	[]	[]	-9	hSpCas9	negative selection	2922249
142578646	142578669	3	+	27260157	SF268	viability	CTGCCCAGCTCCCGCAGGGCGGG	ATR	ENSG00000175054	-0.558343431898409	[]	[]	-4	hSpCas9	negative selection	2923381
142566197	142566220	3	+	27260157	SF268	viability	GATGAAATCAAGCAACATCACGG	ATR	ENSG00000175054	-3.19750551435192	[]	[]	-9	hSpCas9	negative selection	2926370
142578641	142578664	3	+	27260157	SF268	viability	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-3.1076934131286	[]	[]	-9	hSpCas9	negative selection	2928366
142568130	142568153	3	+	27260157	SF268	viability	TGTATTATATTCCTCTGGTGTGG	ATR	ENSG00000175054	-2.95768051097932	[]	[]	-9	hSpCas9	negative selection	2947779
142556487	142556510	3	-	27260157	SF268	viability	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	-1.03123249806961	[]	[]	-7	hSpCas9	negative selection	2948992
142568095	142568118	3	+	27260157	SF268	viability	AATTGACACAGAATTTGTCTTGG	ATR	ENSG00000175054	-1.97653956049062	[]	[]	-8	hSpCas9	negative selection	2951155
142558715	142558738	3	-	27260157	SF268	viability	GTGGTATGCTCTCACTTCCATGG	ATR	ENSG00000175054	0.237358082144885	[]	[]	3	hSpCas9	negative selection	2953271
142562842	142562865	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTCAATTAGATGAACACATGGG	ATR	ENSG00000175054	-0.4048352323839241	[4,4]	[3,2]	-5	hSpCas9	positive selection	2972586
142566201	142566224	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	0.10623357430117002	[3,2]	[4,0]	2	hSpCas9	positive selection	2972587
142558647	142558670	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTAATGTTAGAAGATTAGCGG	ATR	ENSG00000175054	-0.23007253605103314	[4,4]	[3,1]	-3	hSpCas9	positive selection	2972588
142560368	142560391	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTATTCAAGGGAAATCTGAAGGG	ATR	ENSG00000175054	0.23604438405941103	[3,3]	[3,4]	5	hSpCas9	positive selection	2972589
142562842	142562865	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTCAATTAGATGAACACATGGG	ATR	ENSG00000175054	0.29798816109287923	[4,4]	[4,3]	5	hSpCas9	positive selection	3040444
142566201	142566224	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	0.3428145411750497	[3,3]	[4,1]	6	hSpCas9	positive selection	3040445
142558647	142558670	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTAATGTTAGAAGATTAGCGG	ATR	ENSG00000175054	0.0317933063557827	[4,4]	[3,2]	0	hSpCas9	positive selection	3040446
142560368	142560391	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTATTCAAGGGAAATCTGAAGGG	ATR	ENSG00000175054	-0.13061040763208212	[3,3]	[2,1]	-2	hSpCas9	positive selection	3040447
142578641	142578664		+	24336571	A375	resistance to PLX after 7 days	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	0.3759982486329519	[7,9]	[10,11]	8	hSpCas9	positive selection	3139352
142578668	142578691		+	24336571	A375	resistance to PLX after 7 days	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	0.28317698286539866	[10,7]	[9,12]	7	hSpCas9	positive selection	3139363
142568141	142568164		-	24336571	A375	resistance to PLX after 7 days	GTATTTTAGTGCCACACCAGAGG	ATR	ENSG00000175054	-0.3834349391910452	[7,7]	[4,6]	-9	hSpCas9	positive selection	3139374
142578641	142578664		+	24336571	A375	resistance to PLX after 14 days	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	0.5375311624956396	[4,6]	[3,3]	5	hSpCas9	positive selection	3197145
142578668	142578691		+	24336571	A375	resistance to PLX after 14 days	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.2081268416422205	[6,7]	[2,2]	-2	hSpCas9	positive selection	3197156
142568141	142568164		-	24336571	A375	resistance to PLX after 14 days	GTATTTTAGTGCCACACCAGAGG	ATR	ENSG00000175054	1.0442700625739911	[4,4]	[3,5]	8	hSpCas9	positive selection	3197167
142578641	142578664		+	24336571	A375	viability after 7 days	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-1.3627602463544752	[23]	[7,9]	-9	hSpCas9	negative selection	3254938
142578668	142578691		+	24336571	A375	viability after 7 days	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.3303866773739093	[11]	[10,7]	-5	hSpCas9	negative selection	3254949
142568141	142568164		-	24336571	A375	viability after 7 days	GTATTTTAGTGCCACACCAGAGG	ATR	ENSG00000175054	-0.2963646540788456	[10]	[7,7]	-4	hSpCas9	negative selection	3254960
142578641	142578664		+	24336571	A375	viability after 14 days	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-1.790948687650455	[23]	[4,6]	-9	hSpCas9	negative selection	3312731
142578668	142578691		+	24336571	A375	viability after 14 days	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.6242869015001536	[11]	[6,7]	-6	hSpCas9	negative selection	3312742
142568141	142568164		-	24336571	A375	viability after 14 days	GTATTTTAGTGCCACACCAGAGG	ATR	ENSG00000175054	-0.926872005962704	[10]	[4,4]	-8	hSpCas9	negative selection	3312753
142566116	142566139	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	-0.489272265455038	[343,299]	[1,0]	-3	hSpCas9	positive selection	3338239
142578657	142578680	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	1.5583378968888166	[43,59]	[0,0]	6	hSpCas9	positive selection	3338240
142566120	142566143	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	1.2146475441811635	[53,77]	[0,0]	5	hSpCas9	positive selection	3338241
142578668	142578691	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	2.087401210003523	[143,143]	[3,3]	7	hSpCas9	positive selection	3357496
142568085	142568108	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.2818325996621964	[185,185]	[0,0]	-2	hSpCas9	positive selection	3357497
142568125	142568148	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.28956824844180157	[186,186]	[0,0]	-2	hSpCas9	positive selection	3357498
142562842	142562865	3	-	26780180	HT29	viability (Avana library 4 designs)	AGTCAATTAGATGAACACATGGG	ATR	ENSG00000175054	2.79735549827647	[]	[]	8	hSpCas9	negative selection	3408739
142566200	142566223	3	+	26780180	HT29	viability (Avana library 4 designs)	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	4.57822590565459	[]	[]	9	hSpCas9	negative selection	3408740
142558646	142558669	3	+	26780180	HT29	viability (Avana library 4 designs)	GCTTAATGTTAGAAGATTAGCGG	ATR	ENSG00000175054	5.14094422700642	[]	[]	9	hSpCas9	negative selection	3408741
142560367	142560390	3	+	26780180	HT29	viability (Avana library 4 designs)	GTATTCAAGGGAAATCTGAAGGG	ATR	ENSG00000175054	3.58589911026979	[]	[]	9	hSpCas9	negative selection	3408742
142560367	142560390	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTATTCAAGGGAAATCTGAAGGG	ATR	ENSG00000175054	-16.2693929502022	[]	[]	-9	hSpCas9	negative selection	3482425
142562842	142562865	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTCAATTAGATGAACACATGGG	ATR	ENSG00000175054	-10.0294672004123	[]	[]	-7	hSpCas9	negative selection	3482426
142558646	142558669	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTAATGTTAGAAGATTAGCGG	ATR	ENSG00000175054	-13.0487708680483	[]	[]	-8	hSpCas9	negative selection	3482427
142566200	142566223	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-12.2106446111689	[]	[]	-8	hSpCas9	negative selection	3482428
142578642	142578665	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCTGCCCAGCTCCCGCAGGG	ATR	ENSG00000175054	-9.6986700360221	[]	[]	-7	hSpCas9	negative selection	3482429
142553651	142553674	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATACCTTGATTCTTACAACAGGG	ATR	ENSG00000175054	-10.5741863042355	[]	[]	-8	hSpCas9	negative selection	3482430
142560367	142560390	3	+	26780180	A375	viability (Avana lentiGuide)	GTATTCAAGGGAAATCTGAAGGG	ATR	ENSG00000175054	4.58440620495158	[]	[]	4	hSpCas9	negative selection	3591084
142562842	142562865	3	-	26780180	A375	viability (Avana lentiGuide)	AGTCAATTAGATGAACACATGGG	ATR	ENSG00000175054	4.65393020152993	[]	[]	4	hSpCas9	negative selection	3591085
142558646	142558669	3	+	26780180	A375	viability (Avana lentiGuide)	GCTTAATGTTAGAAGATTAGCGG	ATR	ENSG00000175054	15.988697109693	[]	[]	8	hSpCas9	negative selection	3591086
142566200	142566223	3	+	26780180	A375	viability (Avana lentiGuide)	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	6.59332801866795	[]	[]	5	hSpCas9	negative selection	3591087
142578642	142578665	3	+	26780180	A375	viability (Avana lentiGuide)	CTACCTGCCCAGCTCCCGCAGGG	ATR	ENSG00000175054	24.1593487841287	[]	[]	9	hSpCas9	negative selection	3591088
142553651	142553674	3	-	26780180	A375	viability (Avana lentiGuide)	ATACCTTGATTCTTACAACAGGG	ATR	ENSG00000175054	9.99864281007187	[]	[]	7	hSpCas9	negative selection	3591089
142560367	142560390	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATTCAAGGGAAATCTGAAGGG	ATR	ENSG00000175054	-1.4251751019409324	[6]	[1,1]	-9	hSpCas9	positive selection	3699743
142562842	142562865	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTCAATTAGATGAACACATGGG	ATR	ENSG00000175054	-0.5091872936823677	[8]	[4,5]	-6	hSpCas9	positive selection	3699744
142558646	142558669	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTAATGTTAGAAGATTAGCGG	ATR	ENSG00000175054	-0.5533719507819216	[8]	[5,4]	-7	hSpCas9	positive selection	3699745
142566200	142566223	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.2014288698978512	[4]	[0,2]	-9	hSpCas9	positive selection	3699746
142578642	142578665	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCTGCCCAGCTCCCGCAGGG	ATR	ENSG00000175054	-0.830509326817676	[4]	[1,1]	-8	hSpCas9	positive selection	3699747
142553651	142553674	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATACCTTGATTCTTACAACAGGG	ATR	ENSG00000175054	-0.7871123898915013	[7]	[4,3]	-8	hSpCas9	positive selection	3699748
142560367	142560390	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATTCAAGGGAAATCTGAAGGG	ATR	ENSG00000175054	-0.2878181216320825	[5]	[2,3]	-4	hSpCas9	positive selection	3808350
142562842	142562865	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTCAATTAGATGAACACATGGG	ATR	ENSG00000175054	-0.2925408004077575	[6]	[4,4]	-4	hSpCas9	positive selection	3808351
142558646	142558669	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTAATGTTAGAAGATTAGCGG	ATR	ENSG00000175054	-0.40067079278105044	[6]	[4,2]	-5	hSpCas9	positive selection	3808352
142566200	142566223	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-0.5202691000163772	[5]	[3,2]	-6	hSpCas9	positive selection	3808353
142578642	142578665	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCTGCCCAGCTCCCGCAGGG	ATR	ENSG00000175054	-0.4015900663138504	[5]	[1,4]	-5	hSpCas9	positive selection	3808354
142553651	142553674	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATACCTTGATTCTTACAACAGGG	ATR	ENSG00000175054	-0.5161845310832097	[5]	[4,1]	-6	hSpCas9	positive selection	3808355
142568125	142568148	3	+	26780180	A375	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	2.33756627512064	[]	[]	9	hSpCas9	negative selection	3916601
142566116	142566139	3	+	26780180	A375	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	1.79103185992009	[]	[]	9	hSpCas9	negative selection	3916602
142578657	142578680	3	-	26780180	A375	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	1.41824608143144	[]	[]	7	hSpCas9	negative selection	3916603
142566120	142566143	3	-	26780180	A375	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	1.72707325980389	[]	[]	9	hSpCas9	negative selection	3916604
142578668	142578691	3	+	26780180	A375	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	1.48399763017063	[]	[]	8	hSpCas9	negative selection	3916605
142568085	142568108	3	-	26780180	A375	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	1.14624857369515	[]	[]	6	hSpCas9	negative selection	3916606
142568125	142568148	3	+	26780180	HT29	viability (GeCKOv2 library)	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	2.1692491637063	[]	[]	9	hSpCas9	negative selection	4024567
142566116	142566139	3	+	26780180	HT29	viability (GeCKOv2 library)	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	2.11608034707861	[]	[]	9	hSpCas9	negative selection	4024568
142578657	142578680	3	-	26780180	HT29	viability (GeCKOv2 library)	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	1.80986585615797	[]	[]	8	hSpCas9	negative selection	4024569
142566120	142566143	3	-	26780180	HT29	viability (GeCKOv2 library)	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	1.73190487661615	[]	[]	8	hSpCas9	negative selection	4024570
142578668	142578691	3	+	26780180	HT29	viability (GeCKOv2 library)	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	1.73773551831292	[]	[]	8	hSpCas9	negative selection	4024571
142568085	142568108	3	-	26780180	HT29	viability (GeCKOv2 library)	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	1.54681668325875	[]	[]	7	hSpCas9	negative selection	4024572
142578641	142578664	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-0.6315300610735775	[4]	[0,1]	-9	hSpCas9	positive selection	4164677
142578668	142578691	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.25630643234768224	[3]	[2,1]	-6	hSpCas9	positive selection	4164688
142568141	142568164	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTATTTTAGTGCCACACCAGAGG	ATR	ENSG00000175054	0.18933096423030946	[2]	[2,2]	5	hSpCas9	positive selection	4164699
142578641	142578664	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTACCTGCCCAGCTCCCGCAGG	ATR	ENSG00000175054	-0.9395160152931407	[4]	[1,0,0,0]	-9	hSpCas9	positive selection	4228699
142578668	142578691	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.4537295476643936	[3]	[2,0,0,0]	-6	hSpCas9	positive selection	4228710
142568141	142568164	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTATTTTAGTGCCACACCAGAGG	ATR	ENSG00000175054	-0.41150280621891194	[2]	[0,0,0,0]	-6	hSpCas9	positive selection	4228721
142566116	142566139	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.412074126970622	[4]	[3,4]	8	hSpCas9	positive selection	4257511
142578657	142578680	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.36436721945450745	[2]	[2,0]	-6	hSpCas9	positive selection	4257512
142566120	142566143	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.2726904395490618	[2]	[1,1]	-5	hSpCas9	positive selection	4257513
142578668	142578691	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.39383769958959	[3]	[2,0]	-7	hSpCas9	positive selection	4321795
142568085	142568108	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.17607469314299143	[3]	[2,1]	-4	hSpCas9	positive selection	4321796
142568125	142568148	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.6966679529089552	[3]	[2,0]	-9	hSpCas9	positive selection	4321797
142547756	142547778	3	+	27760321	OCIAML3	viability	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	-1.146118401615496	[492,418]	[124,206]	-7	hSpCas9	negative selection	4380797
142550151	142550173	3	+	27760321	OCIAML3	viability	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-1.7422308572950596	[260,195]	[32,78]	-8	hSpCas9	negative selection	4380798
142555876	142555898	3	-	27760321	OCIAML3	viability	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-0.701782312109116	[78,61]	[47,14]	-6	hSpCas9	negative selection	4380799
142556552	142556574	3	+	27760321	OCIAML3	viability	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-0.864227536755068	[661,593]	[252,290]	-7	hSpCas9	negative selection	4380800
142566201	142566223	3	+	27760321	OCIAML3	viability	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.8929890884244456	[598,497]	[91,144]	-9	hSpCas9	negative selection	4380801
142547756	142547778	3	+	27760321	OCIAML2	viability	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	-0.5615289426882437	[492,418]	[274,214]	-6	hSpCas9	negative selection	4464260
142550151	142550173	3	+	27760321	OCIAML2	viability	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-1.1889446506465973	[260,195]	[63,101]	-8	hSpCas9	negative selection	4464261
142555876	142555898	3	-	27760321	OCIAML2	viability	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-1.8327555646750562	[78,61]	[8,24]	-9	hSpCas9	negative selection	4464262
142556552	142556574	3	+	27760321	OCIAML2	viability	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-0.8417563777741626	[661,593]	[242,335]	-7	hSpCas9	negative selection	4464263
142566201	142566223	3	+	27760321	OCIAML2	viability	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.7896546572785734	[598,497]	[78,43]	-9	hSpCas9	negative selection	4464264
142547756	142547778	3	+	27760321	MV411	viability	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	0.005804364081049201	[492,418]	[189,467]	0	hSpCas9	negative selection	4547723
142550151	142550173	3	+	27760321	MV411	viability	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-1.8678300849939897	[260,195]	[0,100]	-8	hSpCas9	negative selection	4547724
142555876	142555898	3	-	27760321	MV411	viability	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-5.530300577065882	[78,61]	[0,0]	-9	hSpCas9	negative selection	4547725
142556552	142556574	3	+	27760321	MV411	viability	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-0.4001866378940766	[661,593]	[150,557]	-3	hSpCas9	negative selection	4547726
142566201	142566223	3	+	27760321	MV411	viability	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-0.7464553640504271	[598,497]	[6,526]	-5	hSpCas9	negative selection	4547727
142547756	142547778	3	+	27760321	HL60	viability	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	-0.6693757777485667	[492,418]	[230,235]	-6	hSpCas9	negative selection	4631186
142550151	142550173	3	+	27760321	HL60	viability	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-1.1979096003092837	[260,195]	[36,126]	-8	hSpCas9	negative selection	4631187
142555876	142555898	3	-	27760321	HL60	viability	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-2.17584127462403	[78,61]	[17,6]	-9	hSpCas9	negative selection	4631188
142556552	142556574	3	+	27760321	HL60	viability	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-1.1704201840923156	[661,593]	[265,186]	-8	hSpCas9	negative selection	4631189
142566201	142566223	3	+	27760321	HL60	viability	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.1208796864433066	[598,497]	[242,164]	-8	hSpCas9	negative selection	4631190
142547756	142547778	3	+	27760321	HT1080	viability	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	0.6476802232740458	[418,326]	[259,202]	3	hSpCas9	negative selection	4714649
142550151	142550173	3	+	27760321	HT1080	viability	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-6.119283184583504	[195,152]	[0,0]	-9	hSpCas9	negative selection	4714650
142555876	142555898	3	-	27760321	HT1080	viability	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-4.467720176825649	[61,48]	[0,0]	-8	hSpCas9	negative selection	4714651
142556552	142556574	3	+	27760321	HT1080	viability	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-2.833422733077541	[593,463]	[30,27]	-7	hSpCas9	negative selection	4714652
142566201	142566223	3	+	27760321	HT1080	viability	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.6204770138625504	[497,388]	[0,28]	-7	hSpCas9	negative selection	4714653
142547756	142547778	3	+	27760321	HT29	viability after 7 days	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	-0.1046739302275023	[418,326]	[466,669,210]	-1	hSpCas9	negative selection	4798112
142550151	142550173	3	+	27760321	HT29	viability after 7 days	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-0.4700587176656561	[195,152]	[183,211,94]	-6	hSpCas9	negative selection	4798113
142555876	142555898	3	-	27760321	HT29	viability after 7 days	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	0.765014727363613	[61,48]	[97,154,107]	9	hSpCas9	negative selection	4798114
142556552	142556574	3	+	27760321	HT29	viability after 7 days	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	0.09723747127520532	[593,463]	[570,751,832]	1	hSpCas9	negative selection	4798115
142566201	142566223	3	+	27760321	HT29	viability after 7 days	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	0.15870895607798097	[497,388]	[558,584,749]	2	hSpCas9	negative selection	4798116
142547756	142547778	3	+	27760321	HT29	viability after 25 days	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	0.08764092827194445	[418,326]	[499,326,536]	0	hSpCas9	negative selection	4881575
142550151	142550173	3	+	27760321	HT29	viability after 25 days	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-4.431298887885186	[195,152]	[6,18,0]	-9	hSpCas9	negative selection	4881576
142555876	142555898	3	-	27760321	HT29	viability after 25 days	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-5.987402441672173	[61,48]	[0,0,0]	-9	hSpCas9	negative selection	4881577
142556552	142556574	3	+	27760321	HT29	viability after 25 days	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-3.111700328159551	[593,463]	[79,102,20]	-8	hSpCas9	negative selection	4881578
142566201	142566223	3	+	27760321	HT29	viability after 25 days	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.557837369812565	[497,388]	[214,61,243]	-7	hSpCas9	negative selection	4881579
142547756	142547778	3	+	27760321	HT29	viability after 22 days	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	-0.2492345422140872	[418,326]	[513,235,333]	-3	hSpCas9	negative selection	4965038
142550151	142550173	3	+	27760321	HT29	viability after 22 days	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-2.8158095185741	[195,152]	[27,25,31]	-8	hSpCas9	negative selection	4965039
142555876	142555898	3	-	27760321	HT29	viability after 22 days	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-4.146330461190669	[61,48]	[0,0,8]	-9	hSpCas9	negative selection	4965040
142556552	142556574	3	+	27760321	HT29	viability after 22 days	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-4.419095229254994	[593,463]	[21,28,34]	-9	hSpCas9	negative selection	4965041
142566201	142566223	3	+	27760321	HT29	viability after 22 days	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.8470275013942516	[497,388]	[68,56,87]	-8	hSpCas9	negative selection	4965042
142547756	142547778	3	+	27760321	HT29	viability after 19 days	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	-0.7393745504125464	[418,326]	[395,206,180]	-5	hSpCas9	negative selection	5048501
142550151	142550173	3	+	27760321	HT29	viability after 19 days	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-2.1233062452131026	[195,152]	[2,32,94]	-8	hSpCas9	negative selection	5048502
142555876	142555898	3	-	27760321	HT29	viability after 19 days	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-5.988881021108219	[61,48]	[0,0,0]	-9	hSpCas9	negative selection	5048503
142556552	142556574	3	+	27760321	HT29	viability after 19 days	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-3.954623906818352	[593,463]	[93,21,7]	-9	hSpCas9	negative selection	5048504
142566201	142566223	3	+	27760321	HT29	viability after 19 days	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.0782513955976385	[497,388]	[115,36,33]	-8	hSpCas9	negative selection	5048505
142547756	142547778	3	+	27760321	HT29	viability after 16 days	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	-0.7785852673478396	[418,326]	[277,244,209]	-6	hSpCas9	negative selection	5131964
142550151	142550173	3	+	27760321	HT29	viability after 16 days	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-3.0871960883862544	[195,152]	[10,52,2]	-9	hSpCas9	negative selection	5131965
142555876	142555898	3	-	27760321	HT29	viability after 16 days	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-3.708831179444779	[61,48]	[0,0,11]	-9	hSpCas9	negative selection	5131966
142556552	142556574	3	+	27760321	HT29	viability after 16 days	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-3.5211764265118544	[593,463]	[90,65,0]	-9	hSpCas9	negative selection	5131967
142566201	142566223	3	+	27760321	HT29	viability after 16 days	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.3226774468417117	[497,388]	[207,275,109]	-7	hSpCas9	negative selection	5131968
142547756	142547778	3	+	27760321	HT29	viability after 13 days	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	-0.22043012071066392	[418,326]	[390,366,356]	-3	hSpCas9	negative selection	5215427
142550151	142550173	3	+	27760321	HT29	viability after 13 days	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-2.4967953957468865	[195,152]	[69,26,11]	-9	hSpCas9	negative selection	5215428
142555876	142555898	3	-	27760321	HT29	viability after 13 days	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-6.0097039681314355	[61,48]	[0,0,0]	-9	hSpCas9	negative selection	5215429
142556552	142556574	3	+	27760321	HT29	viability after 13 days	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-3.083348846034634	[593,463]	[38,151,28]	-9	hSpCas9	negative selection	5215430
142566201	142566223	3	+	27760321	HT29	viability after 13 days	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.4126985332727076	[497,388]	[115,45,125]	-9	hSpCas9	negative selection	5215431
142547756	142547778	3	+	27760321	HT29	viability after 10 days	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	-0.6862368381923751	[418,326]	[409,290,169]	-7	hSpCas9	negative selection	5298890
142550151	142550173	3	+	27760321	HT29	viability after 10 days	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-0.011902302019227262	[195,152]	[340,255,55]	0	hSpCas9	negative selection	5298891
142555876	142555898	3	-	27760321	HT29	viability after 10 days	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-2.0656597147516162	[61,48]	[17,1,28]	-9	hSpCas9	negative selection	5298892
142556552	142556574	3	+	27760321	HT29	viability after 10 days	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-1.1967834689619579	[593,463]	[332,259,270]	-8	hSpCas9	negative selection	5298893
142566201	142566223	3	+	27760321	HT29	viability after 10 days	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.366840180236785	[497,388]	[141,244,256]	-8	hSpCas9	negative selection	5298894
142547756	142547778	3	+	27760321	MOLM13	viability	CCCTGATATGGATCATCACTGG	ATR	ENSG00000175054	0.1557211329075586	[492,418]	[256,309]	1	hSpCas9	negative selection	5382353
142550151	142550173	3	+	27760321	MOLM13	viability	TCAGGAAAGTCGAAAACGTTGG	ATR	ENSG00000175054	-1.514244837699625	[260,195]	[0,81]	-7	hSpCas9	negative selection	5382354
142555876	142555898	3	-	27760321	MOLM13	viability	TACCTAGTCCAGTAAAACTTGG	ATR	ENSG00000175054	-5.3042437642382865	[78,61]	[0,0]	-9	hSpCas9	negative selection	5382355
142556552	142556574	3	+	27760321	MOLM13	viability	CACATCGTGATTGTGCCTGTGG	ATR	ENSG00000175054	-1.5622768004095784	[661,593]	[195,54]	-7	hSpCas9	negative selection	5382356
142566201	142566223	3	+	27760321	MOLM13	viability	AAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.689489191664888	[598,497]	[11,33]	-9	hSpCas9	negative selection	5382357
142578385	142578408	3	+	27661255	K562	viability	GGTGAGTGGTAAACCAGGGCCGG	ATR	ENSG00000175054	-0.3995934375211046	[484,617]	[399,274]	-7	dCas9-KRAB	negative selection	5464397
142578506	142578529	3	+	27661255	K562	viability	GCCACGGAGCATCTCCACAAGGG	ATR	ENSG00000175054	-1.2260577158593429	[592,638]	[242,181]	-8	dCas9-KRAB	negative selection	5464398
142578689	142578712	3	+	27661255	K562	viability	GGCCATGTTCCCCCATGCTGAGG	ATR	ENSG00000175054	-2.3113536053324655	[1089,988]	[206,133]	-9	dCas9-KRAB	negative selection	5464399
142578730	142578753	3	-	27661255	K562	viability	GCCGGGAACCCGCGTTGGCGTGG	ATR	ENSG00000175054	-2.155516604641959	[319,339]	[77,42]	-9	dCas9-KRAB	negative selection	5464400
142578735	142578758	3	-	27661255	K562	viability	GAGACGCCGGGAACCCGCGTTGG	ATR	ENSG00000175054	-3.7694607635979183	[982,1315]	[73,60]	-9	dCas9-KRAB	negative selection	5464401
142578788	142578811	3	-	27661255	K562	viability	GGCCTCCACACGGCTCCGTCGGG	ATR	ENSG00000175054	-2.6189177138043767	[439,344]	[67,36]	-9	dCas9-KRAB	negative selection	5464402
142566116	142566139	3	+	27260156	BXPC3	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.33162013538453605	[1006]	[1235,1232,1367,1489]	7	hSpCas9	negative selection	5529971
142578657	142578680	3	-	27260156	BXPC3	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.2862650431738575	[322]	[181,280,375,278]	-6	hSpCas9	negative selection	5529972
142566120	142566143	3	-	27260156	BXPC3	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.011057292335853786	[396]	[379,293,474,520]	0	hSpCas9	negative selection	5529973
142578668	142578691	3	+	27260156	BXPC3	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.4322487740810531	[643]	[415,376,736,480]	-7	hSpCas9	negative selection	5594255
142568085	142568108	3	-	27260156	BXPC3	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.007601329073131963	[536]	[569,418,623,661]	0	hSpCas9	negative selection	5594256
142568125	142568148	3	+	27260156	BXPC3	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.6064518391999008	[852]	[513,533,605,711]	-8	hSpCas9	negative selection	5594257
142566116	142566139	3	+	27260156	A673	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.12222079794630347	[1006]	[1493,1277,1226,1282]	3	hSpCas9	negative selection	5651222
142578657	142578680	3	-	27260156	A673	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.3753301259124696	[322]	[277,242,223,458]	-7	hSpCas9	negative selection	5651223
142566120	142566143	3	-	27260156	A673	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.3240766964790739	[396]	[341,384,358,434]	-7	hSpCas9	negative selection	5651224
142578668	142578691	3	+	27260156	A673	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.8023130462059531	[643]	[440,501,435,388]	-9	hSpCas9	negative selection	5715506
142568085	142568108	3	-	27260156	A673	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.3015601336323507	[536]	[592,406,552,550]	-6	hSpCas9	negative selection	5715507
142568125	142568148	3	+	27260156	A673	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.7654292016269598	[852]	[653,560,524,680]	-9	hSpCas9	negative selection	5715508
142566116	142566139	3	+	27260156	A375	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	-0.04890799884457753	[1006]	[1255,964,1038,1246]	0	hSpCas9	negative selection	5772473
142578657	142578680	3	-	27260156	A375	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.4115008521305241	[322]	[96,231,80,165]	-9	hSpCas9	negative selection	5772474
142566120	142566143	3	-	27260156	A375	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-1.2340195942665	[396]	[225,205,185,173]	-8	hSpCas9	negative selection	5772475
142578668	142578691	3	+	27260156	A375	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.6490458152859331	[643]	[422,639,555,336]	-7	hSpCas9	negative selection	5836757
142568085	142568108	3	-	27260156	A375	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.22911200795414352	[536]	[732,460,478,464]	-3	hSpCas9	negative selection	5836758
142568125	142568148	3	+	27260156	A375	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.9730648939869404	[852]	[758,457,389,425]	-8	hSpCas9	negative selection	5836759
142566116	142566139	3	+	27260156	COLO741	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.23044855760847294	[1006]	[1717,1518,1319]	5	hSpCas9	negative selection	5893724
142578657	142578680	3	-	27260156	COLO741	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.38816798525521545	[322]	[430,237,287]	-7	hSpCas9	negative selection	5893725
142566120	142566143	3	-	27260156	COLO741	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.49894161139429294	[396]	[329,361,379]	-8	hSpCas9	negative selection	5893726
142578668	142578691	3	+	27260156	COLO741	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.26248228638388116	[643]	[957,631,502]	-5	hSpCas9	negative selection	5958008
142568085	142568108	3	-	27260156	COLO741	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.12754329530061276	[536]	[684,608,595]	-3	hSpCas9	negative selection	5958009
142568125	142568148	3	+	27260156	COLO741	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.7410203874672187	[852]	[717,669,577]	-9	hSpCas9	negative selection	5958010
142566116	142566139	3	+	27260156	CAL120	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.5786235988596291	[1006]	[2301,1603,1773]	8	hSpCas9	negative selection	6014975
142578657	142578680	3	-	27260156	CAL120	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.2113727101305276	[322]	[174,178,166]	-9	hSpCas9	negative selection	6014976
142566120	142566143	3	-	27260156	CAL120	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.20530569243560393	[396]	[387,562,329]	-3	hSpCas9	negative selection	6014977
142578668	142578691	3	+	27260156	CAL120	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.24159925954693123	[643]	[932,540,598]	-4	hSpCas9	negative selection	6079259
142568085	142568108	3	-	27260156	CAL120	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.05627785258788007	[536]	[579,677,659]	-1	hSpCas9	negative selection	6079260
142568125	142568148	3	+	27260156	CAL120	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.8231179762574358	[852]	[524,587,673]	-8	hSpCas9	negative selection	6079261
142566116	142566139	3	+	27260156	CADOES1	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.349362906166218	[1006]	[1231,1237,1026,1278]	6	hSpCas9	negative selection	6136226
142578657	142578680	3	-	27260156	CADOES1	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.7841145194657405	[322]	[163,133,141,260]	-8	hSpCas9	negative selection	6136227
142566120	142566143	3	-	27260156	CADOES1	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.2782624568467743	[396]	[251,397,344,219]	-5	hSpCas9	negative selection	6136228
142578668	142578691	3	+	27260156	CADOES1	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.4054834852605738	[643]	[534,368,564,334]	-6	hSpCas9	negative selection	6200510
142568085	142568108	3	-	27260156	CADOES1	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.3593036696433993	[536]	[563,883,588,521]	6	hSpCas9	negative selection	6200511
142568125	142568148	3	+	27260156	CADOES1	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.8408067263532509	[852]	[530,402,406,429]	-9	hSpCas9	negative selection	6200512
142566116	142566139	3	+	27260156	EWS502	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.2235080751496814	[1006]	[834,1395,1086,1734]	4	hSpCas9	negative selection	6257477
142578657	142578680	3	-	27260156	EWS502	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.258349115306335	[322]	[121,174,125,149]	-9	hSpCas9	negative selection	6257478
142566120	142566143	3	-	27260156	EWS502	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.7684357625806673	[396]	[171,218,267,344]	-8	hSpCas9	negative selection	6257479
142578668	142578691	3	+	27260156	EWS502	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.9381969591812531	[643]	[388,422,282,316]	-8	hSpCas9	negative selection	6321761
142568085	142568108	3	-	27260156	EWS502	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.10852105833654539	[536]	[499,591,494,520]	-2	hSpCas9	negative selection	6321762
142568125	142568148	3	+	27260156	EWS502	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-1.1034535327147275	[852]	[428,391,449,408]	-9	hSpCas9	negative selection	6321763
142566116	142566139	3	+	27260156	EW8	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.11791395429990437	[1006]	[826,938,942,814]	2	hSpCas9	negative selection	6378728
142578657	142578680	3	-	27260156	EW8	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.725676753676144	[322]	[189,114,97,242]	-8	hSpCas9	negative selection	6378729
142566120	142566143	3	-	27260156	EW8	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.34528382367559607	[396]	[202,298,270,230]	-6	hSpCas9	negative selection	6378730
142578668	142578691	3	+	27260156	EW8	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.7306099147729115	[643]	[288,241,324,395]	-8	hSpCas9	negative selection	6443012
142568085	142568108	3	-	27260156	EW8	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.2987761364860914	[536]	[796,445,412,532]	5	hSpCas9	negative selection	6443013
142568125	142568148	3	+	27260156	EW8	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.8304448953136996	[852]	[375,318,363,496]	-9	hSpCas9	negative selection	6443014
142566116	142566139	3	+	27260156	CORL105	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	-0.01670620567873282	[1006]	[961,1139,1487,1114]	0	hSpCas9	negative selection	6499979
142578657	142578680	3	-	27260156	CORL105	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.7064394779157389	[322]	[115,186,299,330]	-8	hSpCas9	negative selection	6499980
142566120	142566143	3	-	27260156	CORL105	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.22380902683143433	[396]	[464,269,295,548]	-4	hSpCas9	negative selection	6499981
142578668	142578691	3	+	27260156	CORL105	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.43653200804105535	[643]	[563,564,592,511]	-7	hSpCas9	negative selection	6564263
142568085	142568108	3	-	27260156	CORL105	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.37816078422749383	[536]	[448,613,581,301]	-6	hSpCas9	negative selection	6564264
142568125	142568148	3	+	27260156	CORL105	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-1.008568056555706	[852]	[410,436,609,542]	-9	hSpCas9	negative selection	6564265
142566116	142566139	3	+	27260156	HS294T	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.5420062648029889	[1006]	[448,611,400,862]	7	hSpCas9	negative selection	6621230
142578657	142578680	3	-	27260156	HS294T	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.111414983159961	[322]	[41,45,66,81]	-9	hSpCas9	negative selection	6621231
142566120	142566143	3	-	27260156	HS294T	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	0.07187615182810486	[396]	[234,66,116,233]	1	hSpCas9	negative selection	6621232
142578668	142578691	3	+	27260156	HS294T	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.849186648762319	[643]	[114,98,163,185]	-8	hSpCas9	negative selection	6685514
142568085	142568108	3	-	27260156	HS294T	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.39335769937195064	[536]	[182,235,387,296]	5	hSpCas9	negative selection	6685515
142568125	142568148	3	+	27260156	HS294T	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-1.158379900865914	[852]	[114,126,156,204]	-9	hSpCas9	negative selection	6685516
142566116	142566139	3	+	27260156	HCC44	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.36500085810381844	[1006]	[1865,1070,1634,1406]	6	hSpCas9	negative selection	6742481
142578657	142578680	3	-	27260156	HCC44	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.1382765997612299	[322]	[301,165,100,96]	-8	hSpCas9	negative selection	6742482
142566120	142566143	3	-	27260156	HCC44	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.35407636576185975	[396]	[465,313,480,184]	-5	hSpCas9	negative selection	6742483
142578668	142578691	3	+	27260156	HCC44	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.2614772581682361	[643]	[763,468,681,558]	-4	hSpCas9	negative selection	6806765
142568085	142568108	3	-	27260156	HCC44	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.05904463951922004	[536]	[679,543,787,371]	-1	hSpCas9	negative selection	6806766
142568125	142568148	3	+	27260156	HCC44	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.7381535462250032	[852]	[851,316,665,551]	-8	hSpCas9	negative selection	6806767
142566116	142566139	3	+	27260156	G402	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.4519068981278196	[1006]	[1494,1724,1745,1723]	5	hSpCas9	negative selection	6863732
142578657	142578680	3	-	27260156	G402	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.5321800013879346	[322]	[140,553,214,180]	-6	hSpCas9	negative selection	6863733
142566120	142566143	3	-	27260156	G402	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.30598500420850616	[396]	[434,275,433,418]	-4	hSpCas9	negative selection	6863734
142578668	142578691	3	+	27260156	G402	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-1.0290678619839992	[643]	[580,329,312,341]	-8	hSpCas9	negative selection	6928016
142568085	142568108	3	-	27260156	G402	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.60362970917281	[536]	[842,1628,661,865]	7	hSpCas9	negative selection	6928017
142568125	142568148	3	+	27260156	G402	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.3915503174300158	[852]	[1052,575,613,944]	-5	hSpCas9	negative selection	6928018
142566116	142566139	3	+	27260156	L33	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.29403326990316314	[1006]	[1080,543,700,1415]	6	hSpCas9	negative selection	6984983
142578657	142578680	3	-	27260156	L33	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.22080716482523333	[322]	[239,114,176,306]	-5	hSpCas9	negative selection	6984984
142566120	142566143	3	-	27260156	L33	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	0.12788083864047178	[396]	[400,208,293,357]	3	hSpCas9	negative selection	6984985
142578668	142578691	3	+	27260156	L33	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.5435085819990689	[643]	[473,173,317,362]	-8	hSpCas9	negative selection	7049267
142568085	142568108	3	-	27260156	L33	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.30216176040032217	[536]	[512,141,230,511]	-6	hSpCas9	negative selection	7049268
142568125	142568148	3	+	27260156	L33	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.8804452206528778	[852]	[505,190,284,426]	-9	hSpCas9	negative selection	7049269
142566116	142566139	3	+	27260156	K562	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.3782569052245144	[1006]	[2028,1065,920,740]	5	hSpCas9	negative selection	7106234
142578657	142578680	3	-	27260156	K562	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.8530771019459086	[322]	[86,132,409,13]	-7	hSpCas9	negative selection	7106235
142566120	142566143	3	-	27260156	K562	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.816328285407762	[396]	[272,315,64,161]	-7	hSpCas9	negative selection	7106236
142578668	142578691	3	+	27260156	K562	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-1.5798081241526454	[643]	[141,116,220,266]	-9	hSpCas9	negative selection	7170518
142568085	142568108	3	-	27260156	K562	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.1495131864188427	[536]	[598,633,527,379]	1	hSpCas9	negative selection	7170519
142568125	142568148	3	+	27260156	K562	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.5391290349771864	[852]	[487,497,460,618]	-6	hSpCas9	negative selection	7170520
142566116	142566139	3	+	27260156	HT29	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.16389312642109566	[1006]	[1655,1337,1231,1279]	3	hSpCas9	negative selection	7227485
142578657	142578680	3	-	27260156	HT29	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.7337048859750576	[322]	[336,171,172,259]	-8	hSpCas9	negative selection	7227486
142566120	142566143	3	-	27260156	HT29	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.9882493745835192	[396]	[237,333,228,184]	-8	hSpCas9	negative selection	7227487
142578668	142578691	3	+	27260156	HT29	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.36481098482399965	[643]	[594,890,422,548]	-6	hSpCas9	negative selection	7291769
142568085	142568108	3	-	27260156	HT29	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.13681954342260477	[536]	[855,727,618,678]	2	hSpCas9	negative selection	7291770
142568125	142568148	3	+	27260156	HT29	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.5755426885082195	[852]	[833,764,699,517]	-7	hSpCas9	negative selection	7291771
142566116	142566139	3	+	27260156	MHHES1	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	-0.3486600718738452	[1006]	[983,760,1146,695]	-6	hSpCas9	negative selection	7348736
142578657	142578680	3	-	27260156	MHHES1	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.6218873203900724	[322]	[329,232,254,152]	-8	hSpCas9	negative selection	7348737
142566120	142566143	3	-	27260156	MHHES1	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.7776318886386269	[396]	[395,391,156,147]	-8	hSpCas9	negative selection	7348738
142578668	142578691	3	+	27260156	MHHES1	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.36376836893022674	[643]	[784,721,423,392]	-6	hSpCas9	negative selection	7413020
142568085	142568108	3	-	27260156	MHHES1	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.15417247251084573	[536]	[451,511,838,383]	-3	hSpCas9	negative selection	7413021
142568125	142568148	3	+	27260156	MHHES1	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.8886439040739526	[852]	[635,445,590,420]	-9	hSpCas9	negative selection	7413022
142566116	142566139	3	+	27260156	MEWO	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	-0.08117925856127362	[1006]	[1110,725,877]	-2	hSpCas9	negative selection	7469987
142578657	142578680	3	-	27260156	MEWO	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.6218821637204927	[322]	[184,166,234]	-8	hSpCas9	negative selection	7469988
142566120	142566143	3	-	27260156	MEWO	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.28657803695742734	[396]	[388,266,273]	-6	hSpCas9	negative selection	7469989
142578668	142578691	3	+	27260156	MEWO	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.8017896196883586	[643]	[397,329,318]	-9	hSpCas9	negative selection	7534271
142568085	142568108	3	-	27260156	MEWO	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.12502962329421724	[536]	[557,423,418]	-3	hSpCas9	negative selection	7534272
142568125	142568148	3	+	27260156	MEWO	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.6277674519328209	[852]	[515,557,474]	-8	hSpCas9	negative selection	7534273
142566116	142566139	3	+	27260156	LNCAPCLONEFGC	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.5539877694417865	[1006]	[1267,1276,1537,1307]	8	hSpCas9	negative selection	7591238
142578657	142578680	3	-	27260156	LNCAPCLONEFGC	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.0314905102448524	[322]	[123,133,146,168]	-9	hSpCas9	negative selection	7591239
142566120	142566143	3	-	27260156	LNCAPCLONEFGC	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.34857998817889746	[396]	[240,269,469,177]	-5	hSpCas9	negative selection	7591240
142578668	142578691	3	+	27260156	LNCAPCLONEFGC	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.6018360051006544	[643]	[343,351,429,420]	-7	hSpCas9	negative selection	7655522
142568085	142568108	3	-	27260156	LNCAPCLONEFGC	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.1678592882418447	[536]	[545,611,605,425]	2	hSpCas9	negative selection	7655523
142568125	142568148	3	+	27260156	LNCAPCLONEFGC	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.6713557119616235	[852]	[289,643,412,575]	-7	hSpCas9	negative selection	7655524
142566116	142566139	3	+	27260156	PANC0327	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.4807452407162742	[1006]	[1723,802,1168,1392]	7	hSpCas9	negative selection	7712489
142578657	142578680	3	-	27260156	PANC0327	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.0470744901100901	[322]	[136,233,130,40]	-8	hSpCas9	negative selection	7712490
142566120	142566143	3	-	27260156	PANC0327	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.02810991645999289	[396]	[262,279,380,460]	0	hSpCas9	negative selection	7712491
142578668	142578691	3	+	27260156	PANC0327	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.9347643925083975	[643]	[420,273,183,330]	-8	hSpCas9	negative selection	7776773
142568085	142568108	3	-	27260156	PANC0327	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.45049926918567995	[536]	[1040,476,729,413]	6	hSpCas9	negative selection	7776774
142568125	142568148	3	+	27260156	PANC0327	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.8155722939162249	[852]	[433,332,521,445]	-8	hSpCas9	negative selection	7776775
142566116	142566139	3	+	27260156	NCIH2009	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.153521379018158	[1006]	[1910,1425,1425]	2	hSpCas9	negative selection	7833740
142578657	142578680	3	-	27260156	NCIH2009	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.7343669541483981	[322]	[156,128,124]	-9	hSpCas9	negative selection	7833741
142566120	142566143	3	-	27260156	NCIH2009	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-1.3062690239021155	[396]	[294,304,84]	-8	hSpCas9	negative selection	7833742
142578668	142578691	3	+	27260156	NCIH2009	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.6400090707182138	[643]	[883,565,341]	-7	hSpCas9	negative selection	7898024
142568085	142568108	3	-	27260156	NCIH2009	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.44857036905164077	[536]	[643,605,415]	-5	hSpCas9	negative selection	7898025
142568125	142568148	3	+	27260156	NCIH2009	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.7951862955626754	[852]	[904,648,548]	-7	hSpCas9	negative selection	7898026
142566116	142566139	3	+	27260156	NCIH1373	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.29770027111746167	[1006]	[1619,1128,1172,448]	3	hSpCas9	negative selection	7954991
142578657	142578680	3	-	27260156	NCIH1373	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.9015413129730115	[322]	[225,62,188,84]	-7	hSpCas9	negative selection	7954992
142566120	142566143	3	-	27260156	NCIH1373	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	0.4237638209730614	[396]	[697,487,515,188]	4	hSpCas9	negative selection	7954993
142578668	142578691	3	+	27260156	NCIH1373	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-1.3564859847531918	[643]	[385,299,251,51]	-8	hSpCas9	negative selection	8019275
142568085	142568108	3	-	27260156	NCIH1373	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.23643788097773238	[536]	[668,693,636,219]	2	hSpCas9	negative selection	8019276
142568125	142568148	3	+	27260156	NCIH1373	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.4145655316432444	[852]	[660,595,1050,142]	-4	hSpCas9	negative selection	8019277
142566116	142566139	3	+	27260156	PATU8902	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.499491539044002	[1006]	[2329,1879,1735,2033]	5	hSpCas9	negative selection	8076242
142578657	142578680	3	-	27260156	PATU8902	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.2565396607393389	[322]	[154,177,203,213]	-8	hSpCas9	negative selection	8076243
142566120	142566143	3	-	27260156	PATU8902	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.4857598958575431	[396]	[406,241,255,748]	-5	hSpCas9	negative selection	8076244
142578668	142578691	3	+	27260156	PATU8902	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.48857754566729494	[643]	[686,858,450,598]	-5	hSpCas9	negative selection	8140526
142568085	142568108	3	-	27260156	PATU8902	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.09041444576103136	[536]	[1114,413,900,704]	0	hSpCas9	negative selection	8140527
142568125	142568148	3	+	27260156	PATU8902	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.9433874759073568	[852]	[764,940,337,476]	-7	hSpCas9	negative selection	8140528
142566116	142566139	3	+	27260156	PANC1	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.33211047711129904	[1006]	[1094,1156,1008,1088]	5	hSpCas9	negative selection	8197493
142578657	142578680	3	-	27260156	PANC1	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.7243776920928097	[322]	[183,223,159,119]	-8	hSpCas9	negative selection	8197494
142566120	142566143	3	-	27260156	PANC1	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.5989965219850876	[396]	[337,201,178,177]	-7	hSpCas9	negative selection	8197495
142578668	142578691	3	+	27260156	PANC1	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.6033940341000446	[643]	[314,407,337,393]	-7	hSpCas9	negative selection	8261777
142568085	142568108	3	-	27260156	PANC1	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.46945100545613105	[536]	[581,959,598,493]	7	hSpCas9	negative selection	8261778
142568125	142568148	3	+	27260156	PANC1	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.6036272955691285	[852]	[540,517,544,345]	-7	hSpCas9	negative selection	8261779
142566116	142566139	3	+	27260156	PANC0813	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.2032688658979005	[1006]	[1353,1611,1200,1280]	3	hSpCas9	negative selection	8318744
142578657	142578680	3	-	27260156	PANC0813	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.9409645798507457	[322]	[279,106,162,244]	-8	hSpCas9	negative selection	8318745
142566120	142566143	3	-	27260156	PANC0813	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.7415966412164426	[396]	[348,180,263,324]	-8	hSpCas9	negative selection	8318746
142578668	142578691	3	+	27260156	PANC0813	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.4919545822219408	[643]	[484,456,709,496]	-6	hSpCas9	negative selection	8383028
142568085	142568108	3	-	27260156	PANC0813	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.12615257862195428	[536]	[803,544,592,399]	-2	hSpCas9	negative selection	8383029
142568125	142568148	3	+	27260156	PANC0813	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.904381351167855	[852]	[605,551,358,623]	-8	hSpCas9	negative selection	8383030
142566116	142566139	3	+	27260156	RDES	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.43997264837597494	[1006]	[1568,1345,1696,1658]	7	hSpCas9	negative selection	8439995
142578657	142578680	3	-	27260156	RDES	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.5213130943186189	[322]	[264,204,243,325]	-7	hSpCas9	negative selection	8439996
142566120	142566143	3	-	27260156	RDES	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.5276387148170896	[396]	[287,270,432,272]	-7	hSpCas9	negative selection	8439997
142578668	142578691	3	+	27260156	RDES	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.5092128418188461	[643]	[509,395,603,580]	-7	hSpCas9	negative selection	8504279
142568085	142568108	3	-	27260156	RDES	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.0639413180088319	[536]	[491,589,699,853]	1	hSpCas9	negative selection	8504280
142568125	142568148	3	+	27260156	RDES	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.9080813760868166	[852]	[439,486,533,655]	-9	hSpCas9	negative selection	8504281
142566116	142566139	3	+	27260156	PC3	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.1865255195424702	[1006]	[808,1253,1833,946]	4	hSpCas9	negative selection	8561246
142578657	142578680	3	-	27260156	PC3	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.32162125484238346	[322]	[93,286,532,278]	-6	hSpCas9	negative selection	8561247
142566120	142566143	3	-	27260156	PC3	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	0.05168019580831501	[396]	[261,478,634,369]	1	hSpCas9	negative selection	8561248
142578668	142578691	3	+	27260156	PC3	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.35521093260900194	[643]	[312,307,963,655]	-7	hSpCas9	negative selection	8625530
142568085	142568108	3	-	27260156	PC3	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.31425526628871314	[536]	[225,519,774,380]	-6	hSpCas9	negative selection	8625531
142568125	142568148	3	+	27260156	PC3	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.9103045689851362	[852]	[330,422,709,449]	-9	hSpCas9	negative selection	8625532
142566116	142566139	3	+	27260156	PATU8988T	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.26970819721321804	[1006]	[1171,1144,1141,1235]	4	hSpCas9	negative selection	8682497
142578657	142578680	3	-	27260156	PATU8988T	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.1183964598606395	[322]	[118,154,107,198]	-9	hSpCas9	negative selection	8682498
142566120	142566143	3	-	27260156	PATU8988T	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	0.18790039451172097	[396]	[393,402,437,515]	3	hSpCas9	negative selection	8682499
142578668	142578691	3	+	27260156	PATU8988T	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.004561962249017448	[643]	[381,674,451,1010]	0	hSpCas9	negative selection	8746781
142568085	142568108	3	-	27260156	PATU8988T	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.444948136956658	[536]	[489,923,826,593]	7	hSpCas9	negative selection	8746782
142568125	142568148	3	+	27260156	PATU8988T	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.6270171581715445	[852]	[627,620,482,400]	-7	hSpCas9	negative selection	8746783
142566116	142566139	3	+	27260156	T47D	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.3872397135528711	[1006]	[1546,1515,1588,1483]	7	hSpCas9	negative selection	8803748
142578657	142578680	3	-	27260156	T47D	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.3136796911082804	[322]	[332,271,258,351]	-6	hSpCas9	negative selection	8803749
142566120	142566143	3	-	27260156	T47D	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.0038383521947364663	[396]	[518,363,465,505]	0	hSpCas9	negative selection	8803750
142578668	142578691	3	+	27260156	T47D	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.07276336363354569	[643]	[706,752,762,622]	-2	hSpCas9	negative selection	8868032
142568085	142568108	3	-	27260156	T47D	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.1995323012224426	[536]	[667,734,691,778]	4	hSpCas9	negative selection	8868033
142568125	142568148	3	+	27260156	T47D	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.5526808360213922	[852]	[601,618,738,755]	-8	hSpCas9	negative selection	8868034
142566116	142566139	3	+	27260156	SU8686	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.10012404773685657	[1006]	[861,1017,1243,1205]	1	hSpCas9	negative selection	8924999
142578657	142578680	3	-	27260156	SU8686	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-1.1578608918860978	[322]	[185,148,160,57]	-9	hSpCas9	negative selection	8925000
142566120	142566143	3	-	27260156	SU8686	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.9391842665482146	[396]	[204,145,211,275]	-8	hSpCas9	negative selection	8925001
142578668	142578691	3	+	27260156	SU8686	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.7677099511953682	[643]	[370,373,314,447]	-8	hSpCas9	negative selection	8989283
142568085	142568108	3	-	27260156	SU8686	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.027848626018611683	[536]	[370,522,552,681]	0	hSpCas9	negative selection	8989284
142568125	142568148	3	+	27260156	SU8686	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-1.139765464822268	[852]	[344,376,364,462]	-8	hSpCas9	negative selection	8989285
142566116	142566139	3	+	27260156	SKES1	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.17493522006052742	[1006]	[1220,1271,1069,1005]	4	hSpCas9	negative selection	9046250
142578657	142578680	3	-	27260156	SKES1	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.05634217125497887	[322]	[279,322,471,172]	-1	hSpCas9	negative selection	9046251
142566120	142566143	3	-	27260156	SKES1	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.244505951292096	[396]	[465,279,325,279]	-5	hSpCas9	negative selection	9046252
142578668	142578691	3	+	27260156	SKES1	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.6605679414280758	[643]	[385,507,427,318]	-8	hSpCas9	negative selection	9110534
142568085	142568108	3	-	27260156	SKES1	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.06346472889486793	[536]	[637,592,496,524]	1	hSpCas9	negative selection	9110535
142568125	142568148	3	+	27260156	SKES1	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.7703609107026067	[852]	[483,619,484,422]	-9	hSpCas9	negative selection	9110536
142566116	142566139	3	+	27260156	TOV112D	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.31287397116749327	[1006]	[1168,1160,1268,1376]	6	hSpCas9	negative selection	9167501
142578657	142578680	3	-	27260156	TOV112D	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.22331477821506185	[322]	[231,245,249,365]	-4	hSpCas9	negative selection	9167502
142566120	142566143	3	-	27260156	TOV112D	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.35141756525557377	[396]	[443,375,246,208]	-6	hSpCas9	negative selection	9167503
142578668	142578691	3	+	27260156	TOV112D	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.561371567640292	[643]	[418,709,309,375]	-8	hSpCas9	negative selection	9231785
142568085	142568108	3	-	27260156	TOV112D	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.040641303691932085	[536]	[442,745,394,553]	-1	hSpCas9	negative selection	9231786
142568125	142568148	3	+	27260156	TOV112D	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.8787348864433638	[852]	[587,436,505,333]	-9	hSpCas9	negative selection	9231787
142566116	142566139	3	+	27260156	TC71	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.304069528691596	[1006]	[1229,1310,1285,1518]	7	hSpCas9	negative selection	9288752
142578657	142578680	3	-	27260156	TC71	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.3926198216890795	[322]	[207,300,208,344]	-8	hSpCas9	negative selection	9288753
142566120	142566143	3	-	27260156	TC71	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.01783331453456677	[396]	[381,504,411,380]	0	hSpCas9	negative selection	9288754
142578668	142578691	3	+	27260156	TC71	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.4982819419621335	[643]	[456,571,440,486]	-8	hSpCas9	negative selection	9353036
142568085	142568108	3	-	27260156	TC71	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	0.026332147534873007	[536]	[414,533,661,744]	0	hSpCas9	negative selection	9353037
142568125	142568148	3	+	27260156	TC71	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.35216241358821576	[852]	[605,717,725,823]	-7	hSpCas9	negative selection	9353038
142566116	142566139	3	+	27260156	TC32	viability	CTTACCAATACAACTGCCTTTGG	ATR	ENSG00000175054	0.1305137240857932	[1006]	[1161,517,1313,1336]	2	hSpCas9	negative selection	9410003
142578657	142578680	3	-	27260156	TC32	viability	CTTCCATGATCCCCGCCCTGCGG	ATR	ENSG00000175054	-0.14068735735545745	[322]	[256,176,382,329]	-3	hSpCas9	negative selection	9410004
142566120	142566143	3	-	27260156	TC32	viability	GAGGCCAAAGGCAGTTGTATTGG	ATR	ENSG00000175054	-0.3603077124473886	[396]	[206,214,472,323]	-6	hSpCas9	negative selection	9410005
142578668	142578691	3	+	27260156	TC32	viability	GGATCATGGAAGCCAGCTCCAGG	ATR	ENSG00000175054	-0.4570304317099772	[643]	[290,501,491,454]	-7	hSpCas9	negative selection	9474287
142568085	142568108	3	-	27260156	TC32	viability	TTCTGTGTCAATTCATTGACCGG	ATR	ENSG00000175054	-0.25318853071908043	[536]	[437,175,621,569]	-4	hSpCas9	negative selection	9474288
142568125	142568148	3	+	27260156	TC32	viability	ACAACTGTATTATATTCCTCTGG	ATR	ENSG00000175054	-0.5518254740264179	[852]	[510,360,678,711]	-8	hSpCas9	negative selection	9474289
142519717	142519740	3	+	27869803	HPAFII	viability after 27 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.8564079177095708	[308]	[44,126,NaN]	-6	hSpCas9	negative selection	9582934
142553215	142553238	3	+	27869803	HPAFII	viability after 27 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-5.595981501681309	[91]	[0,0,NaN]	-9	hSpCas9	negative selection	9582935
142556487	142556510	3	-	27869803	HPAFII	viability after 27 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.42710108691806786	[253]	[172,184,NaN]	3	hSpCas9	negative selection	9582936
142559305	142559328	3	-	27869803	HPAFII	viability after 27 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.8699473115280518	[194]	[296,95,NaN]	7	hSpCas9	negative selection	9582937
142562882	142562905	3	-	27869803	HPAFII	viability after 27 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-3.007362522566753	[202]	[27,0,NaN]	-9	hSpCas9	negative selection	9582938
142566200	142566223	3	+	27869803	HPAFII	viability after 27 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.494888552216269	[288]	[0,97,NaN]	-7	hSpCas9	negative selection	9582939
142519717	142519740	3	+	27869803	HPAFII	viability after 15 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.19782408551208686	[308]	[172,361,NaN]	-2	hSpCas9	negative selection	9665383
142553215	142553238	3	+	27869803	HPAFII	viability after 15 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-2.8185436489937548	[91]	[5,18,NaN]	-9	hSpCas9	negative selection	9665384
142556487	142556510	3	-	27869803	HPAFII	viability after 15 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	1.0710262611966663	[253]	[895,372,NaN]	9	hSpCas9	negative selection	9665385
142559305	142559328	3	-	27869803	HPAFII	viability after 15 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.6904719645463544	[194]	[619,162,NaN]	7	hSpCas9	negative selection	9665386
142562882	142562905	3	-	27869803	HPAFII	viability after 15 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-5.283701318744457	[202]	[12,0,NaN]	-9	hSpCas9	negative selection	9665387
142566200	142566223	3	+	27869803	HPAFII	viability after 15 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.5752775972733	[288]	[32,63,NaN]	-9	hSpCas9	negative selection	9665388
142519717	142519740	3	+	27869803	ASPC1	viability after 36 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	0.33476541188211006	[723]	[95,573,268]	3	hSpCas9	negative selection	9747832
142553215	142553238	3	+	27869803	ASPC1	viability after 36 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-0.27720346746551194	[170]	[68,33,46]	-3	hSpCas9	negative selection	9747833
142556487	142556510	3	-	27869803	ASPC1	viability after 36 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	1.1850753631943234	[707]	[1086,359,347]	9	hSpCas9	negative selection	9747834
142559305	142559328	3	-	27869803	ASPC1	viability after 36 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	-0.634243558647041	[408]	[142,56,82]	-6	hSpCas9	negative selection	9747835
142562882	142562905	3	-	27869803	ASPC1	viability after 36 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-0.9769081402436743	[488]	[0,194,59]	-7	hSpCas9	negative selection	9747836
142566200	142566223	3	+	27869803	ASPC1	viability after 36 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.578582700807526	[574]	[0,0,81]	-9	hSpCas9	negative selection	9747837
142519717	142519740	3	+	27869803	PATU8988S	viability after 35 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	0.8028737433407209	[566]	[349,446,NaN]	8	hSpCas9	negative selection	9830281
142553215	142553238	3	+	27869803	PATU8988S	viability after 35 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-2.8357909734395217	[114]	[0,11,NaN]	-9	hSpCas9	negative selection	9830282
142556487	142556510	3	-	27869803	PATU8988S	viability after 35 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.046342929158693785	[619]	[194,320,NaN]	0	hSpCas9	negative selection	9830283
142559305	142559328	3	-	27869803	PATU8988S	viability after 35 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.17720198881024507	[290]	[139,124,NaN]	2	hSpCas9	negative selection	9830284
142562882	142562905	3	-	27869803	PATU8988S	viability after 35 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-2.425868121394459	[465]	[2,66,NaN]	-9	hSpCas9	negative selection	9830285
142566200	142566223	3	+	27869803	PATU8988S	viability after 35 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.9101305738111634	[559]	[63,55,NaN]	-9	hSpCas9	negative selection	9830286
142519717	142519740	3	+	27869803	PATU8988S	viability after 31 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	0.6891763778963622	[566]	[243,517,NaN]	7	hSpCas9	negative selection	9912730
142553215	142553238	3	+	27869803	PATU8988S	viability after 31 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-3.342931710212834	[114]	[0,8,NaN]	-9	hSpCas9	negative selection	9912731
142556487	142556510	3	-	27869803	PATU8988S	viability after 31 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	-0.13207165931010495	[619]	[196,261,NaN]	-1	hSpCas9	negative selection	9912732
142559305	142559328	3	-	27869803	PATU8988S	viability after 31 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	0.2576823263495893	[290]	[165,103,NaN]	3	hSpCas9	negative selection	9912733
142562882	142562905	3	-	27869803	PATU8988S	viability after 31 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-2.8872044603948663	[465]	[3,51,NaN]	-9	hSpCas9	negative selection	9912734
142566200	142566223	3	+	27869803	PATU8988S	viability after 31 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.120227241231523	[559]	[53,47,NaN]	-9	hSpCas9	negative selection	9912735
142519717	142519740	3	+	27869803	HPAFII	viability after 35 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.7652547878943194	[308]	[44,144,NaN]	-4	hSpCas9	negative selection	9995179
142553215	142553238	3	+	27869803	HPAFII	viability after 35 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-5.541473403060338	[91]	[0,0,NaN]	-9	hSpCas9	negative selection	9995180
142556487	142556510	3	-	27869803	HPAFII	viability after 35 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.5421877077461993	[253]	[206,164,NaN]	3	hSpCas9	negative selection	9995181
142559305	142559328	3	-	27869803	HPAFII	viability after 35 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	1.1036466929048419	[194]	[261,155,NaN]	7	hSpCas9	negative selection	9995182
142562882	142562905	3	-	27869803	HPAFII	viability after 35 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-4.816054101237037	[202]	[5,0,NaN]	-9	hSpCas9	negative selection	9995183
142566200	142566223	3	+	27869803	HPAFII	viability after 35 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-0.7408767602978417	[288]	[0,184,NaN]	-4	hSpCas9	negative selection	9995184
142519717	142519740	3	+	27869803	HPAFII	viability after 31 days	CTCCTCCACAATTGGTGACCTGG	ATR	ENSG00000175054	-0.842328180052329	[308]	[56,139,NaN]	-5	hSpCas9	negative selection	10077628
142553215	142553238	3	+	27869803	HPAFII	viability after 31 days	GCTGACTCTTACCTGACAGATGG	ATR	ENSG00000175054	-5.690190756381755	[91]	[0,0,NaN]	-9	hSpCas9	negative selection	10077629
142556487	142556510	3	-	27869803	HPAFII	viability after 31 days	GGAGAACAGCAGTTTACAACTGG	ATR	ENSG00000175054	0.6226227932227022	[253]	[218,219,NaN]	4	hSpCas9	negative selection	10077630
142559305	142559328	3	-	27869803	HPAFII	viability after 31 days	ATCTGTTCAGAAACTGGACCTGG	ATR	ENSG00000175054	1.1934318500780154	[194]	[356,133,NaN]	8	hSpCas9	negative selection	10077631
142562882	142562905	3	-	27869803	HPAFII	viability after 31 days	TCATGCTGTGGAATGGCCAGTGG	ATR	ENSG00000175054	-3.2530260044165322	[202]	[21,0,NaN]	-9	hSpCas9	negative selection	10077632
142566200	142566223	3	+	27869803	HPAFII	viability after 31 days	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.326976017902529	[288]	[0,133,NaN]	-7	hSpCas9	negative selection	10077633
142566200	142566223	3	+	28162770	P31FUJ	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.2958120019401793	[116]	[13]	-9	hSpCas9	negative selection	10116256
142519735	142519758	3	-	28162770	P31FUJ	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-1.2937702217058058	[289]	[138]	-7	hSpCas9	negative selection	10116257
142561244	142561267	3	-	28162770	P31FUJ	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	-0.3682388294714004	[278]	[253]	-3	hSpCas9	negative selection	10116258
142519719	142519742	3	-	28162770	P31FUJ	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-2.24251735924759	[148]	[36]	-8	hSpCas9	negative selection	10116259
142508031	142508054	3	+	28162770	P31FUJ	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-2.138061714443969	[220]	[58]	-8	hSpCas9	negative selection	10116260
142493232	142493255	3	-	28162770	P31FUJ	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.32206954251146586	[299]	[281]	-3	hSpCas9	negative selection	10116261
142461978	142462001	3	-	28162770	P31FUJ	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-3.192160219917033	[279]	[35]	-9	hSpCas9	negative selection	10116262
142563039	142563062	3	+	28162770	P31FUJ	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	0.45544150575555037	[264]	[426]	5	hSpCas9	negative selection	10116263
142562231	142562254	3	-	28162770	P31FUJ	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-2.31610485110894	[605]	[142]	-8	hSpCas9	negative selection	10116264
142559284	142559307	3	-	28162770	P31FUJ	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-3.6281034856319603	[241]	[22]	-9	hSpCas9	negative selection	10116265
142566200	142566223	3	+	28162770	TF1	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10285622
142519735	142519758	3	-	28162770	TF1	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	NaN	[NaN]	[226]	1	hSpCas9	negative selection	10285623
142561244	142561267	3	-	28162770	TF1	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	NaN	[NaN]	[174]	1	hSpCas9	negative selection	10285624
142519719	142519742	3	-	28162770	TF1	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10285625
142508031	142508054	3	+	28162770	TF1	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10285626
142493232	142493255	3	-	28162770	TF1	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10285627
142461978	142462001	3	-	28162770	TF1	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10285628
142563039	142563062	3	+	28162770	TF1	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10285629
142562231	142562254	3	-	28162770	TF1	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10285630
142559284	142559307	3	-	28162770	TF1	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10285631
142566200	142566223	3	+	28162770	SKM1	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.160803611473764	[42]	[16]	-8	hSpCas9	negative selection	10454988
142519735	142519758	3	-	28162770	SKM1	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.8427602581888027	[69]	[68]	-6	hSpCas9	negative selection	10454989
142561244	142561267	3	-	28162770	SKM1	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	0.08488889758651308	[87]	[164]	0	hSpCas9	negative selection	10454990
142519719	142519742	3	-	28162770	SKM1	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-0.5692356276420387	[46]	[55]	-4	hSpCas9	negative selection	10454991
142508031	142508054	3	+	28162770	SKM1	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-0.75787136060229	[43]	[45]	-5	hSpCas9	negative selection	10454992
142493232	142493255	3	-	28162770	SKM1	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.8659450456096026	[99]	[96]	-6	hSpCas9	negative selection	10454993
142461978	142462001	3	-	28162770	SKM1	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-3.085036103855799	[95]	[19]	-9	hSpCas9	negative selection	10454994
142563039	142563062	3	+	28162770	SKM1	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	-0.14082388204154628	[57]	[92]	-1	hSpCas9	negative selection	10454995
142562231	142562254	3	-	28162770	SKM1	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-3.121561979880913	[127]	[25]	-9	hSpCas9	negative selection	10454996
142559284	142559307	3	-	28162770	SKM1	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-3.254961105298112	[53]	[9]	-9	hSpCas9	negative selection	10454997
142566200	142566223	3	+	28162770	SKM1	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.160803611473764	[42]	[16]	-8	hSpCas9	negative selection	10624354
142519735	142519758	3	-	28162770	SKM1	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.8427602581888027	[69]	[68]	-6	hSpCas9	negative selection	10624355
142561244	142561267	3	-	28162770	SKM1	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	0.08488889758651308	[87]	[164]	0	hSpCas9	negative selection	10624356
142519719	142519742	3	-	28162770	SKM1	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-0.5692356276420387	[46]	[55]	-4	hSpCas9	negative selection	10624357
142508031	142508054	3	+	28162770	SKM1	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-0.75787136060229	[43]	[45]	-5	hSpCas9	negative selection	10624358
142493232	142493255	3	-	28162770	SKM1	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.8659450456096026	[99]	[96]	-6	hSpCas9	negative selection	10624359
142461978	142462001	3	-	28162770	SKM1	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-3.085036103855799	[95]	[19]	-9	hSpCas9	negative selection	10624360
142563039	142563062	3	+	28162770	SKM1	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	-0.14082388204154628	[57]	[92]	-1	hSpCas9	negative selection	10624361
142562231	142562254	3	-	28162770	SKM1	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-3.121561979880913	[127]	[25]	-9	hSpCas9	negative selection	10624362
142559284	142559307	3	-	28162770	SKM1	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-3.254961105298112	[53]	[9]	-9	hSpCas9	negative selection	10624363
142566200	142566223	3	+	28162770	PL21	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-0.6280940372441999	[173]	[48]	-4	hSpCas9	negative selection	10793720
142519735	142519758	3	-	28162770	PL21	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.4917380901483481	[209]	[64]	-4	hSpCas9	negative selection	10793721
142561244	142561267	3	-	28162770	PL21	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	0.4425004520583641	[327]	[193]	4	hSpCas9	negative selection	10793722
142519719	142519742	3	-	28162770	PL21	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-2.372750053931261	[118]	[9]	-8	hSpCas9	negative selection	10793723
142508031	142508054	3	+	28162770	PL21	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-3.4437165752854044	[224]	[8]	-9	hSpCas9	negative selection	10793724
142493232	142493255	3	-	28162770	PL21	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	0.8325216116869785	[408]	[316]	7	hSpCas9	negative selection	10793725
142461978	142462001	3	-	28162770	PL21	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-1.0377242156095678	[249]	[52]	-6	hSpCas9	negative selection	10793726
142563039	142563062	3	+	28162770	PL21	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	0.4360687901605158	[196]	[115]	4	hSpCas9	negative selection	10793727
142562231	142562254	3	-	28162770	PL21	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-1.2631443296435836	[374]	[67]	-7	hSpCas9	negative selection	10793728
142559284	142559307	3	-	28162770	PL21	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-1.679566151792968	[183]	[24]	-8	hSpCas9	negative selection	10793729
142566200	142566223	3	+	28162770	P31FUJ	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.2958120019401793	[116]	[13]	-9	hSpCas9	negative selection	10963086
142519735	142519758	3	-	28162770	P31FUJ	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-1.2937702217058058	[289]	[138]	-7	hSpCas9	negative selection	10963087
142561244	142561267	3	-	28162770	P31FUJ	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	-0.3682388294714004	[278]	[253]	-3	hSpCas9	negative selection	10963088
142519719	142519742	3	-	28162770	P31FUJ	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-2.24251735924759	[148]	[36]	-8	hSpCas9	negative selection	10963089
142508031	142508054	3	+	28162770	P31FUJ	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-2.138061714443969	[220]	[58]	-8	hSpCas9	negative selection	10963090
142493232	142493255	3	-	28162770	P31FUJ	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.32206954251146586	[299]	[281]	-3	hSpCas9	negative selection	10963091
142461978	142462001	3	-	28162770	P31FUJ	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-3.192160219917033	[279]	[35]	-9	hSpCas9	negative selection	10963092
142563039	142563062	3	+	28162770	P31FUJ	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	0.45544150575555037	[264]	[426]	5	hSpCas9	negative selection	10963093
142562231	142562254	3	-	28162770	P31FUJ	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-2.31610485110894	[605]	[142]	-8	hSpCas9	negative selection	10963094
142559284	142559307	3	-	28162770	P31FUJ	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-3.6281034856319603	[241]	[22]	-9	hSpCas9	negative selection	10963095
142566200	142566223	3	+	28162770	OCIAML5	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.895135292755883	[67]	[32]	-7	hSpCas9	negative selection	11132452
142519735	142519758	3	-	28162770	OCIAML5	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-1.2546131259596438	[114]	[86]	-6	hSpCas9	negative selection	11132453
142561244	142561267	3	-	28162770	OCIAML5	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	-0.8017933643827733	[140]	[145]	-5	hSpCas9	negative selection	11132454
142519719	142519742	3	-	28162770	OCIAML5	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-2.1739946657513594	[44]	[17]	-8	hSpCas9	negative selection	11132455
142508031	142508054	3	+	28162770	OCIAML5	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-3.366639743693755	[79]	[13]	-9	hSpCas9	negative selection	11132456
142493232	142493255	3	-	28162770	OCIAML5	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.7552815083291171	[244]	[261]	-5	hSpCas9	negative selection	11132457
142461978	142462001	3	-	28162770	OCIAML5	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-4.579987025427196	[211]	[15]	-9	hSpCas9	negative selection	11132458
142563039	142563062	3	+	28162770	OCIAML5	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	-0.3240064613773178	[180]	[260]	-2	hSpCas9	negative selection	11132459
142562231	142562254	3	-	28162770	OCIAML5	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-2.6776260882991916	[318]	[89]	-8	hSpCas9	negative selection	11132460
142559284	142559307	3	-	28162770	OCIAML5	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-2.781677242972599	[159]	[41]	-8	hSpCas9	negative selection	11132461
142566200	142566223	3	+	28162770	EOL1	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.7635082221147256	[231]	[8]	-9	hSpCas9	negative selection	11301818
142519735	142519758	3	-	28162770	EOL1	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	0.22472131381737545	[293]	[180]	2	hSpCas9	negative selection	11301819
142561244	142561267	3	-	28162770	EOL1	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	-0.17794930235148698	[626]	[291]	-1	hSpCas9	negative selection	11301820
142519719	142519742	3	-	28162770	EOL1	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-3.3693659471472315	[254]	[12]	-9	hSpCas9	negative selection	11301821
142508031	142508054	3	+	28162770	EOL1	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-4.657405979278284	[478]	[9]	-9	hSpCas9	negative selection	11301822
142493232	142493255	3	-	28162770	EOL1	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	0.3601075947227237	[697]	[471]	3	hSpCas9	negative selection	11301823
142461978	142462001	3	-	28162770	EOL1	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-0.9724950380816368	[364]	[97]	-6	hSpCas9	negative selection	11301824
142563039	142563062	3	+	28162770	EOL1	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	0.18934263526876588	[272]	[163]	1	hSpCas9	negative selection	11301825
142562231	142562254	3	-	28162770	EOL1	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-0.3522924337882899	[566]	[233]	-3	hSpCas9	negative selection	11301826
142559284	142559307	3	-	28162770	EOL1	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-1.1190791608297237	[234]	[56]	-6	hSpCas9	negative selection	11301827
142566200	142566223	3	+	28162770	MOLM13	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.292159825734669	[209]	[30]	-8	hSpCas9	negative selection	11471184
142519735	142519758	3	-	28162770	MOLM13	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.8263959582736549	[335]	[136]	-4	hSpCas9	negative selection	11471185
142561244	142561267	3	-	28162770	MOLM13	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	-0.17478861703286475	[458]	[293]	-1	hSpCas9	negative selection	11471186
142519719	142519742	3	-	28162770	MOLM13	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-0.7521590993235698	[204]	[87]	-4	hSpCas9	negative selection	11471187
142508031	142508054	3	+	28162770	MOLM13	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-6.034610958984604	[271]	[2]	-9	hSpCas9	negative selection	11471188
142493232	142493255	3	-	28162770	MOLM13	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.21283210198200808	[544]	[339]	-1	hSpCas9	negative selection	11471189
142461978	142462001	3	-	28162770	MOLM13	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-4.805129112861836	[463]	[11]	-9	hSpCas9	negative selection	11471190
142563039	142563062	3	+	28162770	MOLM13	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	-0.8540387133427837	[284]	[113]	-5	hSpCas9	negative selection	11471191
142562231	142562254	3	-	28162770	MOLM13	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-3.732360156754531	[624]	[33]	-9	hSpCas9	negative selection	11471192
142559284	142559307	3	-	28162770	MOLM13	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-2.489041896563535	[263]	[33]	-8	hSpCas9	negative selection	11471193
142566200	142566223	3	+	28162770	HEL	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-1.6711519438215867	[178]	[35]	-7	hSpCas9	negative selection	11640550
142519735	142519758	3	-	28162770	HEL	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.21221083519636	[207]	[114]	-1	hSpCas9	negative selection	11640551
142561244	142561267	3	-	28162770	HEL	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	0.2468101556692177	[399]	[303]	2	hSpCas9	negative selection	11640552
142519719	142519742	3	-	28162770	HEL	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-3.303680127794799	[184]	[11]	-9	hSpCas9	negative selection	11640553
142508031	142508054	3	+	28162770	HEL	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-3.9301508364202244	[237]	[9]	-9	hSpCas9	negative selection	11640554
142493232	142493255	3	-	28162770	HEL	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	0.0320896876155512	[509]	[333]	0	hSpCas9	negative selection	11640555
142461978	142462001	3	-	28162770	HEL	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-2.780472598724187	[353]	[32]	-8	hSpCas9	negative selection	11640556
142563039	142563062	3	+	28162770	HEL	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	-0.22233158791353447	[254]	[139]	-2	hSpCas9	negative selection	11640557
142562231	142562254	3	-	28162770	HEL	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-2.741925018234968	[469]	[44]	-8	hSpCas9	negative selection	11640558
142559284	142559307	3	-	28162770	HEL	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-4.624047708694545	[230]	[5]	-9	hSpCas9	negative selection	11640559
142566200	142566223	3	+	28162770	MV411	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.7311887984246574	[133]	[16]	-9	hSpCas9	negative selection	11809916
142519735	142519758	3	-	28162770	MV411	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	0.23926361933707507	[176]	[175]	2	hSpCas9	negative selection	11809917
142561244	142561267	3	-	28162770	MV411	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	0.0019615163332862284	[293]	[247]	0	hSpCas9	negative selection	11809918
142519719	142519742	3	-	28162770	MV411	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-0.7398513974676705	[112]	[56]	-5	hSpCas9	negative selection	11809919
142508031	142508054	3	+	28162770	MV411	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-3.852098122768139	[239]	[13]	-9	hSpCas9	negative selection	11809920
142493232	142493255	3	-	28162770	MV411	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	0.4039806695593151	[348]	[388]	3	hSpCas9	negative selection	11809921
142461978	142462001	3	-	28162770	MV411	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-4.0273565685134916	[270]	[13]	-9	hSpCas9	negative selection	11809922
142563039	142563062	3	+	28162770	MV411	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	-0.07073840924347949	[191]	[153]	0	hSpCas9	negative selection	11809923
142562231	142562254	3	-	28162770	MV411	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-0.4027232158461582	[429]	[273]	-3	hSpCas9	negative selection	11809924
142559284	142559307	3	-	28162770	MV411	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-1.8285113024505233	[155]	[36]	-8	hSpCas9	negative selection	11809925
142566200	142566223	3	+	28162770	MONOMAC1	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-3.8215277119673474	[110]	[8]	-9	hSpCas9	negative selection	11979282
142519735	142519758	3	-	28162770	MONOMAC1	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.36166754883235286	[101]	[90]	-3	hSpCas9	negative selection	11979283
142561244	142561267	3	-	28162770	MONOMAC1	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	-0.02409049364200444	[211]	[238]	0	hSpCas9	negative selection	11979284
142519719	142519742	3	-	28162770	MONOMAC1	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-1.7039968357794366	[107]	[37]	-8	hSpCas9	negative selection	11979285
142508031	142508054	3	+	28162770	MONOMAC1	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-2.4391116342577015	[122]	[25]	-9	hSpCas9	negative selection	11979286
142493232	142493255	3	-	28162770	MONOMAC1	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.25962138443757665	[211]	[202]	-2	hSpCas9	negative selection	11979287
142461978	142462001	3	-	28162770	MONOMAC1	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-1.548800171487679	[170]	[66]	-8	hSpCas9	negative selection	11979288
142563039	142563062	3	+	28162770	MONOMAC1	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	1.196982870950207	[120]	[317]	9	hSpCas9	negative selection	11979289
142562231	142562254	3	-	28162770	MONOMAC1	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-2.268421480296319	[289]	[68]	-9	hSpCas9	negative selection	11979290
142559284	142559307	3	-	28162770	MONOMAC1	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-1.8281695292136357	[126]	[40]	-8	hSpCas9	negative selection	11979291
142566200	142566223	3	+	28162770	OCIAML2	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.885667324521005	[19]	[14]	-9	hSpCas9	negative selection	12148648
142519735	142519758	3	-	28162770	OCIAML2	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.9451683362696669	[32]	[94]	-6	hSpCas9	negative selection	12148649
142561244	142561267	3	-	28162770	OCIAML2	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	-0.3463016902399595	[74]	[326]	-3	hSpCas9	negative selection	12148650
142519719	142519742	3	-	28162770	OCIAML2	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-1.8605763435581744	[18]	[28]	-8	hSpCas9	negative selection	12148651
142508031	142508054	3	+	28162770	OCIAML2	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-3.5045771571654987	[42]	[20]	-9	hSpCas9	negative selection	12148652
142493232	142493255	3	-	28162770	OCIAML2	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	-0.2525375413393386	[71]	[334]	-2	hSpCas9	negative selection	12148653
142461978	142462001	3	-	28162770	OCIAML2	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-3.7462642678555884	[45]	[18]	-9	hSpCas9	negative selection	12148654
142563039	142563062	3	+	28162770	OCIAML2	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	-0.24545496323438631	[36]	[172]	-2	hSpCas9	negative selection	12148655
142562231	142562254	3	-	28162770	OCIAML2	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-2.0354144440256867	[70]	[95]	-8	hSpCas9	negative selection	12148656
142559284	142559307	3	-	28162770	OCIAML2	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-2.0181176205446545	[37]	[51]	-8	hSpCas9	negative selection	12148657
142566200	142566223	3	+	28162770	OCIAML3	viability	GAAATCAAGCAACATCACGGAGG	ATR	ENSG00000175054	-2.0992429485745854	[43]	[30]	-8	hSpCas9	negative selection	12318014
142519735	142519758	3	-	28162770	OCIAML3	viability	GAGATGGAGACCAACGGCCCAGG	ATR	ENSG00000175054	-0.512477754827565	[42]	[90]	-4	hSpCas9	negative selection	12318015
142561244	142561267	3	-	28162770	OCIAML3	viability	AAGAGCACCAAAACAGACTGAGG	ATR	ENSG00000175054	-0.7884460000896099	[114]	[200]	-5	hSpCas9	negative selection	12318016
142519719	142519742	3	-	28162770	OCIAML3	viability	GCCCAGGTCACCAATTGTGGAGG	ATR	ENSG00000175054	-2.8284728939611865	[39]	[16]	-9	hSpCas9	negative selection	12318017
142508031	142508054	3	+	28162770	OCIAML3	viability	GCTACTGCCAGAGTATCCTGGGG	ATR	ENSG00000175054	-3.886789389552009	[48]	[9]	-9	hSpCas9	negative selection	12318018
142493232	142493255	3	-	28162770	OCIAML3	viability	GAAAATGAAACCCCACCTGAGGG	ATR	ENSG00000175054	0.08730992429212847	[110]	[355]	0	hSpCas9	negative selection	12318019
142461978	142462001	3	-	28162770	OCIAML3	viability	GAATGGGTGAACAACACTGCTGG	ATR	ENSG00000175054	-1.8164000616606113	[90]	[77]	-8	hSpCas9	negative selection	12318020
142563039	142563062	3	+	28162770	OCIAML3	viability	CTTGTGTAACAAATGACAGGAGG	ATR	ENSG00000175054	0.7438619984322208	[53]	[272]	6	hSpCas9	negative selection	12318021
142562231	142562254	3	-	28162770	OCIAML3	viability	TGGAATTGAGGTAGATGCAGAGG	ATR	ENSG00000175054	-0.9830499310700626	[109]	[167]	-6	hSpCas9	negative selection	12318022
142559284	142559307	3	-	28162770	OCIAML3	viability	GGAGGCAACCATTGATAAGGTGG	ATR	ENSG00000175054	-2.390474246239031	[65]	[37]	-9	hSpCas9	negative selection	12318023