Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:672
• Symbol:BRCA1
• Description:BRCA1 DNA repair associated

DataSource: http://genomecrispr.dkfz.de/#!/results/BRCA1

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
43099812	43099835	17	-	26472758	Jiyoye	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.013275613959334853	[177]	[132]	0	hSpCas9	negative selection	15934
43071102	43071125	17	+	26472758	Jiyoye	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	-0.04420396483669076	[200]	[146]	0	hSpCas9	negative selection	15935
43082527	43082550	17	-	26472758	Jiyoye	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	0.4655920677311955	[120]	[125]	3	hSpCas9	negative selection	15936
43070940	43070963	17	+	26472758	Jiyoye	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-0.41327519816341374	[82]	[46]	-3	hSpCas9	negative selection	15937
43057060	43057083	17	-	26472758	Jiyoye	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.9904169833135614	[136]	[25]	-8	hSpCas9	negative selection	15938
43082496	43082519	17	-	26472758	Jiyoye	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.4974767419066457	[160]	[42]	-7	hSpCas9	negative selection	15939
43057086	43057109	17	-	26472758	Jiyoye	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-0.48733148964681283	[144]	[77]	-3	hSpCas9	negative selection	15940
43047676	43047699	17	+	26472758	Jiyoye	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-0.05225623713142413	[10]	[7]	0	hSpCas9	negative selection	15941
43047651	43047674	17	-	26472758	Jiyoye	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-2.133392999856829	[191]	[32]	-8	hSpCas9	negative selection	15942
43071157	43071180	17	+	26472758	Jiyoye	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.8334216352081648	[318]	[134]	-5	hSpCas9	negative selection	15943
43099812	43099835	17	-	26472758	KBM7	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-1.2414903115306157	[864,726]	[182,134]	-7	hSpCas9	negative selection	207052
43071102	43071125	17	+	26472758	KBM7	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	-0.52921425295454	[966,923]	[311,305]	-5	hSpCas9	negative selection	207053
43082527	43082550	17	-	26472758	KBM7	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-0.6615968394514518	[653,496]	[225,118]	-5	hSpCas9	negative selection	207054
43070940	43070963	17	+	26472758	KBM7	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-2.127022129946437	[654,313]	[49,50]	-8	hSpCas9	negative selection	207055
43057060	43057083	17	-	26472758	KBM7	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.3346511933411236	[615,271]	[62,94]	-7	hSpCas9	negative selection	207056
43082496	43082519	17	-	26472758	KBM7	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.5513523330934278	[902,511]	[160,65]	-8	hSpCas9	negative selection	207057
43057086	43057109	17	-	26472758	KBM7	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	0.4483481417479173	[444,513]	[473,165]	5	hSpCas9	negative selection	207058
43047676	43047699	17	+	26472758	KBM7	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-0.9906789993547165	[122,128]	[19,38]	-6	hSpCas9	negative selection	207059
43047651	43047674	17	-	26472758	KBM7	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-1.5589624346320274	[675,696]	[95,122]	-8	hSpCas9	negative selection	207060
43071157	43071180	17	+	26472758	KBM7	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.457576916612203	[1131,805]	[276,372]	-4	hSpCas9	negative selection	207061
43099812	43099835	17	-	26472758	Raji	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.6792128265172073	[344]	[49]	-5	hSpCas9	negative selection	398170
43071102	43071125	17	+	26472758	Raji	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	-0.4326665434719825	[505]	[86]	-4	hSpCas9	negative selection	398171
43082527	43082550	17	-	26472758	Raji	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-0.4867974953769354	[313]	[51]	-4	hSpCas9	negative selection	398172
43070940	43070963	17	+	26472758	Raji	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-0.8334543921582569	[214]	[27]	-6	hSpCas9	negative selection	398173
43057060	43057083	17	-	26472758	Raji	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	0.20523085877174413	[227]	[60]	2	hSpCas9	negative selection	398174
43082496	43082519	17	-	26472758	Raji	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-0.6492265879388769	[418]	[61]	-5	hSpCas9	negative selection	398175
43057086	43057109	17	-	26472758	Raji	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-0.942604600458077	[322]	[38]	-6	hSpCas9	negative selection	398176
43047676	43047699	17	+	26472758	Raji	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-0.874469117916141	[78]	[9]	-6	hSpCas9	negative selection	398177
43047651	43047674	17	-	26472758	Raji	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-0.824029379368988	[266]	[34]	-6	hSpCas9	negative selection	398178
43071157	43071180	17	+	26472758	Raji	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.8550021728266228	[794]	[101]	-6	hSpCas9	negative selection	398179
43099812	43099835	17	-	26472758	K562	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.05856780356745528	[680]	[551]	0	hSpCas9	negative selection	589288
43071102	43071125	17	+	26472758	K562	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	0.44845158342902347	[835]	[962]	3	hSpCas9	negative selection	589289
43082527	43082550	17	-	26472758	K562	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	0.01881674985410897	[524]	[448]	0	hSpCas9	negative selection	589290
43070940	43070963	17	+	26472758	K562	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-0.8825541285913185	[272]	[124]	-5	hSpCas9	negative selection	589291
43057060	43057083	17	-	26472758	K562	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	0.31179416300797713	[250]	[262]	2	hSpCas9	negative selection	589292
43082496	43082519	17	-	26472758	K562	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.0752356157007947	[633]	[253]	-5	hSpCas9	negative selection	589293
43057086	43057109	17	-	26472758	K562	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	0.32361089508343577	[318]	[336]	2	hSpCas9	negative selection	589294
43047676	43047699	17	+	26472758	K562	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	0.4212964897505258	[68]	[77]	3	hSpCas9	negative selection	589295
43047651	43047674	17	-	26472758	K562	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-0.3911698461246773	[521]	[335]	-3	hSpCas9	negative selection	589296
43071157	43071180	17	+	26472758	K562	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-1.023485297740559	[1008]	[418]	-5	hSpCas9	negative selection	589297
43074341	43074364	17	-	26627737	DLD1	viability	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-1.3531497815616698	[897]	[102,64,152]	-8	hSpCas9	negative selection	798000
43076560	43076583	17	-	26627737	DLD1	viability	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.20872860328423326	[151]	[38,62,61]	2	hSpCas9	negative selection	798001
43082470	43082493	17	+	26627737	DLD1	viability	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-1.4225191955484324	[348]	[32,80,13]	-8	hSpCas9	negative selection	798002
43092301	43092324	17	-	26627737	DLD1	viability	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.32212823793135403	[854]	[177,192,261]	-3	hSpCas9	negative selection	798003
43099851	43099874	17	+	26627737	DLD1	viability	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.5115689848589795	[495]	[143,137,53]	-5	hSpCas9	negative selection	798004
43124001	43124024	17	+	26627737	DLD1	viability	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-5.105644294537169	[180]	[2,0,0]	-9	hSpCas9	negative selection	798005
43074341	43074364	17	-	26627737	GBM cells	viability after 5 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.9047427753674688	[486]	[142,135]	-8	hSpCas9	negative selection	880315
43076560	43076583	17	-	26627737	GBM cells	viability after 5 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.21361040054197228	[159]	[91,106]	3	hSpCas9	negative selection	880316
43082470	43082493	17	+	26627737	GBM cells	viability after 5 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	0.7909311940126738	[103]	[65,126]	9	hSpCas9	negative selection	880317
43092301	43092324	17	-	26627737	GBM cells	viability after 5 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.40993515798217706	[850]	[302,383]	-6	hSpCas9	negative selection	880318
43099851	43099874	17	+	26627737	GBM cells	viability after 5 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.5149596912595223	[412]	[149,159]	-7	hSpCas9	negative selection	880319
43124001	43124024	17	+	26627737	GBM cells	viability after 5 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-0.8511078721059673	[110]	[32,32]	-8	hSpCas9	negative selection	880320
43074341	43074364	17	-	26627737	GBM cells	viability after 13 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-1.0715133456916581	[486]	[133,118]	-8	hSpCas9	negative selection	962630
43076560	43076583	17	-	26627737	GBM cells	viability after 13 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	-0.07904242424889629	[159]	[106,61]	-1	hSpCas9	negative selection	962631
43082470	43082493	17	+	26627737	GBM cells	viability after 13 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	0.38104706692290335	[103]	[78,68]	5	hSpCas9	negative selection	962632
43092301	43092324	17	-	26627737	GBM cells	viability after 13 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.5827142372617076	[850]	[363,262]	-6	hSpCas9	negative selection	962633
43099851	43099874	17	+	26627737	GBM cells	viability after 13 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-1.431833315820157	[412]	[60,100]	-9	hSpCas9	negative selection	962634
43124001	43124024	17	+	26627737	GBM cells	viability after 13 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.9622286300598195	[110]	[31,1]	-9	hSpCas9	negative selection	962635
43074341	43074364	17	-	26627737	GBM cells	viability after 21 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-1.0111878621736485	[486]	[124,136]	-7	hSpCas9	negative selection	1044945
43076560	43076583	17	-	26627737	GBM cells	viability after 21 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.22506179661309955	[159]	[110,92]	2	hSpCas9	negative selection	1044946
43082470	43082493	17	+	26627737	GBM cells	viability after 21 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.2577943752293448	[103]	[52,41]	-2	hSpCas9	negative selection	1044947
43092301	43092324	17	-	26627737	GBM cells	viability after 21 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.1898961066389877	[850]	[444,368]	-2	hSpCas9	negative selection	1044948
43099851	43099874	17	+	26627737	GBM cells	viability after 21 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-2.114265694932965	[412]	[55,47]	-9	hSpCas9	negative selection	1044949
43124001	43124024	17	+	26627737	GBM cells	viability after 21 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-5.914182566734448	[110]	[0,0]	-9	hSpCas9	negative selection	1044950
43074341	43074364	17	-	26627737	RPE1	viability after 9 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.43487407274180395	[669]	[176,126]	-3	hSpCas9	negative selection	1127260
43076560	43076583	17	-	26627737	RPE1	viability after 9 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.4289657930337136	[185]	[87,65]	3	hSpCas9	negative selection	1127261
43082470	43082493	17	+	26627737	RPE1	viability after 9 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-1.6714087643989837	[554]	[47,62]	-8	hSpCas9	negative selection	1127262
43092301	43092324	17	-	26627737	RPE1	viability after 9 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-1.4705997875686645	[2773]	[308,318]	-8	hSpCas9	negative selection	1127263
43099851	43099874	17	+	26627737	RPE1	viability after 9 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.6034829752248109	[979]	[135,286]	-4	hSpCas9	negative selection	1127264
43124001	43124024	17	+	26627737	RPE1	viability after 9 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-4.628547376774374	[285]	[0,6]	-9	hSpCas9	negative selection	1127265
43074341	43074364	17	-	26627737	RPE1	viability after 12 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-1.1923053386067728	[669]	[70,86]	-7	hSpCas9	negative selection	1209575
43076560	43076583	17	-	26627737	RPE1	viability after 12 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.5752909521882743	[185]	[72,75]	4	hSpCas9	negative selection	1209576
43082470	43082493	17	+	26627737	RPE1	viability after 12 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-1.9285027107300707	[554]	[27,50]	-8	hSpCas9	negative selection	1209577
43092301	43092324	17	-	26627737	RPE1	viability after 12 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-1.307473315651904	[2773]	[321,278]	-7	hSpCas9	negative selection	1209578
43099851	43099874	17	+	26627737	RPE1	viability after 12 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-1.025151301442517	[979]	[175,79]	-6	hSpCas9	negative selection	1209579
43124001	43124024	17	+	26627737	RPE1	viability after 12 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-3.3874183928563406	[285]	[1,12]	-9	hSpCas9	negative selection	1209580
43074341	43074364	17	-	26627737	RPE1	viability after 15 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.3303733096465759	[669]	[277,27]	-2	hSpCas9	negative selection	1291890
43076560	43076583	17	-	26627737	RPE1	viability after 15 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	1.3800502339699916	[185]	[139,133]	7	hSpCas9	negative selection	1291891
43082470	43082493	17	+	26627737	RPE1	viability after 15 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-2.7791449768306733	[554]	[1,42]	-9	hSpCas9	negative selection	1291892
43092301	43092324	17	-	26627737	RPE1	viability after 15 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-1.4569652252676337	[2773]	[266,303]	-7	hSpCas9	negative selection	1291893
43099851	43099874	17	+	26627737	RPE1	viability after 15 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-1.8583548124051723	[979]	[78,73]	-8	hSpCas9	negative selection	1291894
43124001	43124024	17	+	26627737	RPE1	viability after 15 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-4.318670100240323	[285]	[0,6]	-9	hSpCas9	negative selection	1291895
43074341	43074364	17	-	26627737	RPE1	viability after 18 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-2.602669659951437	[669]	[22,36]	-8	hSpCas9	negative selection	1374205
43076560	43076583	17	-	26627737	RPE1	viability after 18 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	1.0675523380291803	[185]	[81,129]	6	hSpCas9	negative selection	1374206
43082470	43082493	17	+	26627737	RPE1	viability after 18 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-2.6385827828840096	[554]	[10,37]	-8	hSpCas9	negative selection	1374207
43092301	43092324	17	-	26627737	RPE1	viability after 18 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.5847630999966202	[2773]	[517,478]	-4	hSpCas9	negative selection	1374208
43099851	43099874	17	+	26627737	RPE1	viability after 18 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.6961875675575355	[979]	[169,155]	-4	hSpCas9	negative selection	1374209
43124001	43124024	17	+	26627737	RPE1	viability after 18 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-3.725687218900375	[285]	[0,10]	-9	hSpCas9	negative selection	1374210
43074341	43074364	17	-	26627737	HeLa	viability after 8 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.652721957529783	[685]	[337,85,178]	-6	hSpCas9	negative selection	1456520
43076560	43076583	17	-	26627737	HeLa	viability after 8 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.4512789070536536	[184]	[117,89,122]	4	hSpCas9	negative selection	1456521
43082470	43082493	17	+	26627737	HeLa	viability after 8 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.5488512991842579	[269]	[68,52,113]	-5	hSpCas9	negative selection	1456522
43092301	43092324	17	-	26627737	HeLa	viability after 8 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	0.0012180710737683675	[1399]	[807,443,619]	0	hSpCas9	negative selection	1456523
43099851	43099874	17	+	26627737	HeLa	viability after 8 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.14595229303424823	[405]	[259,135,203]	1	hSpCas9	negative selection	1456524
43124001	43124024	17	+	26627737	HeLa	viability after 8 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-0.5159545459039752	[248]	[135,49,55]	-5	hSpCas9	negative selection	1456525
43074341	43074364	17	-	26627737	HeLa	viability after 12 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.6428648075711973	[685]	[302,60,196]	-5	hSpCas9	negative selection	1538835
43076560	43076583	17	-	26627737	HeLa	viability after 12 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.6456797833245764	[184]	[152,79,130]	5	hSpCas9	negative selection	1538836
43082470	43082493	17	+	26627737	HeLa	viability after 12 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.09628830607179906	[269]	[71,58,185]	-1	hSpCas9	negative selection	1538837
43092301	43092324	17	-	26627737	HeLa	viability after 12 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.39227867871284894	[1399]	[498,366,465]	-3	hSpCas9	negative selection	1538838
43099851	43099874	17	+	26627737	HeLa	viability after 12 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.5383038025791217	[405]	[360,190,187]	4	hSpCas9	negative selection	1538839
43124001	43124024	17	+	26627737	HeLa	viability after 12 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.52204806448059	[248]	[17,44,42]	-8	hSpCas9	negative selection	1538840
43074341	43074364	17	-	26627737	HeLa	viability after 15 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.49935958007235864	[685]	[187,204,199]	-4	hSpCas9	negative selection	1621150
43076560	43076583	17	-	26627737	HeLa	viability after 15 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.7699194873349366	[184]	[171,116,92]	6	hSpCas9	negative selection	1621151
43082470	43082493	17	+	26627737	HeLa	viability after 15 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	0.14028557633570105	[269]	[117,129,114]	1	hSpCas9	negative selection	1621152
43092301	43092324	17	-	26627737	HeLa	viability after 15 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.5206466354323551	[1399]	[429,465,286]	-4	hSpCas9	negative selection	1621153
43099851	43099874	17	+	26627737	HeLa	viability after 15 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.6498868025321901	[405]	[179,315,284]	5	hSpCas9	negative selection	1621154
43124001	43124024	17	+	26627737	HeLa	viability after 15 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.2082789239399248	[248]	[25,47,58]	-8	hSpCas9	negative selection	1621155
43074341	43074364	17	-	26627737	HeLa	viability after 18 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.5119461820865633	[685]	[124,166,199]	-4	hSpCas9	negative selection	1703465
43076560	43076583	17	-	26627737	HeLa	viability after 18 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.7956224197233801	[184]	[118,97,92]	6	hSpCas9	negative selection	1703466
43082470	43082493	17	+	26627737	HeLa	viability after 18 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	0.18198986695498653	[269]	[88,103,114]	1	hSpCas9	negative selection	1703467
43092301	43092324	17	-	26627737	HeLa	viability after 18 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.5214011062721666	[1399]	[291,380,286]	-4	hSpCas9	negative selection	1703468
43099851	43099874	17	+	26627737	HeLa	viability after 18 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.6558829299324644	[405]	[120,263,284]	5	hSpCas9	negative selection	1703469
43124001	43124024	17	+	26627737	HeLa	viability after 18 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.243209622641295	[248]	[15,38,58]	-8	hSpCas9	negative selection	1703470
43074341	43074364	17	-	26627737	HCT116	viability after 6 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	0.7357644273506991	[850]	[439,102]	4	hSpCas9	negative selection	1785780
43076560	43076583	17	-	26627737	HCT116	viability after 6 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.6111260812028111	[239]	[7,84]	3	hSpCas9	negative selection	1785781
43082470	43082493	17	+	26627737	HCT116	viability after 6 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-1.5387375350668742	[330]	[24,13]	-7	hSpCas9	negative selection	1785782
43092301	43092324	17	-	26627737	HCT116	viability after 6 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.6394297591001175	[1982]	[368,106]	-4	hSpCas9	negative selection	1785783
43099851	43099874	17	+	26627737	HCT116	viability after 6 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-1.0866876728733827	[1002]	[90,64]	-6	hSpCas9	negative selection	1785784
43124001	43124024	17	+	26627737	HCT116	viability after 6 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.4189788598011428	[510]	[40,23]	-7	hSpCas9	negative selection	1785785
43074341	43074364	17	-	26627737	HCT116	viability after 8 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.15686814174009533	[561]	[312,247,272]	-2	hSpCas9	negative selection	1868095
43076560	43076583	17	-	26627737	HCT116	viability after 8 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.05153269288803819	[169]	[113,117,59]	0	hSpCas9	negative selection	1868096
43082470	43082493	17	+	26627737	HCT116	viability after 8 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.1996729513941823	[341]	[225,153,113]	-2	hSpCas9	negative selection	1868097
43092301	43092324	17	-	26627737	HCT116	viability after 8 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.44481812335190885	[1075]	[428,469,407]	-5	hSpCas9	negative selection	1868098
43099851	43099874	17	+	26627737	HCT116	viability after 8 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.9750405058172529	[208]	[244,251,182]	8	hSpCas9	negative selection	1868099
43124001	43124024	17	+	26627737	HCT116	viability after 8 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	0.15113609838231257	[154]	[70,109,102]	1	hSpCas9	negative selection	1868100
43074341	43074364	17	-	26627737	HCT116	viability after 9 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	0.563440650764077	[850]	[227,420]	4	hSpCas9	negative selection	1950410
43076560	43076583	17	-	26627737	HCT116	viability after 9 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	-0.7454476873144198	[239]	[78,5]	-5	hSpCas9	negative selection	1950411
43082470	43082493	17	+	26627737	HCT116	viability after 9 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	0.8304952125374205	[330]	[145,165]	6	hSpCas9	negative selection	1950412
43092301	43092324	17	-	26627737	HCT116	viability after 9 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-1.255996603380688	[1982]	[338,128]	-7	hSpCas9	negative selection	1950413
43099851	43099874	17	+	26627737	HCT116	viability after 9 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-1.031197084647002	[1002]	[163,104]	-6	hSpCas9	negative selection	1950414
43124001	43124024	17	+	26627737	HCT116	viability after 9 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	0.07809632148618814	[510]	[157,132]	0	hSpCas9	negative selection	1950415
43074341	43074364	17	-	26627737	HCT116	viability after 12 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.613877628517097	[561]	[113,237,234]	-6	hSpCas9	negative selection	2032725
43076560	43076583	17	-	26627737	HCT116	viability after 12 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	-0.35411777089907837	[169]	[40,101,69]	-4	hSpCas9	negative selection	2032726
43082470	43082493	17	+	26627737	HCT116	viability after 12 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.17364522597221416	[341]	[203,112,155]	-2	hSpCas9	negative selection	2032727
43092301	43092324	17	-	26627737	HCT116	viability after 12 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.8235750810358018	[1075]	[266,395,301]	-7	hSpCas9	negative selection	2032728
43099851	43099874	17	+	26627737	HCT116	viability after 12 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.7188310793105703	[208]	[165,237,140]	6	hSpCas9	negative selection	2032729
43124001	43124024	17	+	26627737	HCT116	viability after 12 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-0.34368700106194705	[154]	[71,68,50]	-4	hSpCas9	negative selection	2032730
43074341	43074364	17	-	26627737	HCT116	viability after 15 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.6692851824790458	[561]	[152,264,184]	-6	hSpCas9	negative selection	2115040
43076560	43076583	17	-	26627737	HCT116	viability after 15 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.001753640415776081	[169]	[72,99,116]	0	hSpCas9	negative selection	2115041
43082470	43082493	17	+	26627737	HCT116	viability after 15 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.09297382278534337	[341]	[168,146,233]	-1	hSpCas9	negative selection	2115042
43092301	43092324	17	-	26627737	HCT116	viability after 15 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.8885320476334755	[1075]	[382,260,362]	-7	hSpCas9	negative selection	2115043
43099851	43099874	17	+	26627737	HCT116	viability after 15 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.6761129192587857	[208]	[224,129,223]	6	hSpCas9	negative selection	2115044
43124001	43124024	17	+	26627737	HCT116	viability after 15 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-0.5985986126783724	[154]	[113,3,64]	-6	hSpCas9	negative selection	2115045
43074341	43074364	17	-	26627737	HCT116	viability after 18 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.29705941348427134	[561]	[214,329,105]	-3	hSpCas9	negative selection	2197355
43076560	43076583	17	-	26627737	HCT116	viability after 18 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	-0.22320761977785097	[169]	[27,63,121]	-2	hSpCas9	negative selection	2197356
43082470	43082493	17	+	26627737	HCT116	viability after 18 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.6385739576778747	[341]	[141,53,126]	-5	hSpCas9	negative selection	2197357
43092301	43092324	17	-	26627737	HCT116	viability after 18 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.8534148345178039	[1075]	[306,294,259]	-7	hSpCas9	negative selection	2197358
43099851	43099874	17	+	26627737	HCT116	viability after 18 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.552805059885439	[208]	[170,135,137]	4	hSpCas9	negative selection	2197359
43124001	43124024	17	+	26627737	HCT116	viability after 18 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.3497676250058983	[154]	[42,16,28]	-8	hSpCas9	negative selection	2197360
43099838	43099861	17	+	24336569	HL60	viability	CAGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-0.3952263103115945	[1012]	[1629]	-4	hSpCas9	negative selection	2250279
43099843	43099866	17	-	24336569	HL60	viability	AGTGTCCAACTCTCTAACCTTGG	BRCA1	ENSG00000012048	0.7142326162443331	[425]	[1478]	6	hSpCas9	negative selection	2250280
43099851	43099874	17	+	24336569	HL60	viability	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.8331691058310509	[1032]	[1226]	-6	hSpCas9	negative selection	2250281
43104166	43104189	17	+	24336569	HL60	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-1.09331381850664	[488]	[484]	-7	hSpCas9	negative selection	2250282
43104177	43104200	17	-	24336569	HL60	viability	GTTTCTATCATCCAAAGTATGGG	BRCA1	ENSG00000012048	0.8273111393245652	[611]	[2297]	6	hSpCas9	negative selection	2250283
43104931	43104954	17	+	24336569	HL60	viability	TAAATCTCGTACTTTCTTGTAGG	BRCA1	ENSG00000012048	0.7427893460020761	[193]	[686]	6	hSpCas9	negative selection	2250284
43106462	43106485	17	+	24336569	HL60	viability	GTTATATCATTCTTACATAAAGG	BRCA1	ENSG00000012048	1.834855907899553	[243]	[1841]	9	hSpCas9	negative selection	2250285
43106474	43106497	17	+	24336569	HL60	viability	TTACATAAAGGACACTGTGAAGG	BRCA1	ENSG00000012048	-1.2075014580702088	[776]	[711]	-8	hSpCas9	negative selection	2250286
43106487	43106510	17	+	24336569	HL60	viability	ACTGTGAAGGCCCTTTCTTCTGG	BRCA1	ENSG00000012048	0.2014698626426023	[329]	[802]	2	hSpCas9	negative selection	2250287
43106497	43106520	17	-	24336569	HL60	viability	AACTTCTCAACCAGAAGAAAGGG	BRCA1	ENSG00000012048	0.3132463739689606	[544]	[1432]	3	hSpCas9	negative selection	2250288
43099838	43099861	17	+	24336569	KBM7	viability	CAGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-1.4873692266545993	[918]	[893]	-7	hSpCas9	negative selection	2317456
43099843	43099866	17	-	24336569	KBM7	viability	AGTGTCCAACTCTCTAACCTTGG	BRCA1	ENSG00000012048	-0.22926026979885933	[455]	[1060]	-2	hSpCas9	negative selection	2317457
43099851	43099874	17	+	24336569	KBM7	viability	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.35600259419674285	[411]	[877]	-3	hSpCas9	negative selection	2317458
43104166	43104189	17	+	24336569	KBM7	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.8468681619163727	[158]	[779]	7	hSpCas9	negative selection	2317459
43104177	43104200	17	-	24336569	KBM7	viability	GTTTCTATCATCCAAAGTATGGG	BRCA1	ENSG00000012048	0.5764949384299751	[623]	[2537]	5	hSpCas9	negative selection	2317460
43104931	43104954	17	+	24336569	KBM7	viability	TAAATCTCGTACTTTCTTGTAGG	BRCA1	ENSG00000012048	-0.22251264091410927	[230]	[539]	-2	hSpCas9	negative selection	2317461
43106462	43106485	17	+	24336569	KBM7	viability	GTTATATCATTCTTACATAAAGG	BRCA1	ENSG00000012048	0.18327270268433293	[525]	[1628]	1	hSpCas9	negative selection	2317462
43106474	43106497	17	+	24336569	KBM7	viability	TTACATAAAGGACACTGTGAAGG	BRCA1	ENSG00000012048	-1.6919350493579008	[352]	[297]	-8	hSpCas9	negative selection	2317463
43106487	43106510	17	+	24336569	KBM7	viability	ACTGTGAAGGCCCTTTCTTCTGG	BRCA1	ENSG00000012048	0.16511260969232316	[291]	[892]	1	hSpCas9	negative selection	2317464
43106497	43106520	17	-	24336569	KBM7	viability	AACTTCTCAACCAGAAGAAAGGG	BRCA1	ENSG00000012048	0.32185445066896945	[412]	[1407]	3	hSpCas9	negative selection	2317465
43066434	43066457	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAGTCTCACTCTGTCGCCAGG	BRCA1	ENSG00000012048	3.8475142164822467	[640,932]	[1963,3090]	9	dCas9-VP64	positive selection	2395776
43048353	43048376	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGCGTAGGGG	BRCA1	ENSG00000012048	-0.9180937029961482	[133,53]	[15,3]	-5	dCas9-VP64	positive selection	2405007
43123500	43123523	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGCGTAGTGG	BRCA1	ENSG00000012048	-0.9180937029961482	[133,53]	[15,3]	-5	dCas9-VP64	positive selection	2405035
43083387	43083410	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAAGTGATCAGCCCGCCTCGG	BRCA1	ENSG00000012048	-0.290662032548316	[293,148]	[57,18]	-1	dCas9-VP64	positive selection	2427354
43067993	43068016	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGCCACCGCGCCCAGCCGAG	BRCA1	ENSG00000012048	-0.6476236116882323	[118,215]	[30,13]	-3	dCas9-VP64	positive selection	2438048
43124362	43124385	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCTGTAGCTTTCTCTTTCTTGG	BRCA1	ENSG00000012048	0.5546784923388741	[142,118]	[23,60]	2	dCas9-VP64	positive selection	2441514
43124376	43124399	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTACAGAGGAGTGACTGACCGG	BRCA1	ENSG00000012048	2.259736643862493	[56,110]	[9,174]	7	dCas9-VP64	positive selection	2441515
43124355	43124378	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTTTCTCTTTCTTGGAGAAAGG	BRCA1	ENSG00000012048	0.19494153076485543	[48,462]	[8,125]	0	dCas9-VP64	positive selection	2441516
43097490	43097513	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCCCAGCACTTGAG	BRCA1	ENSG00000012048	-0.7697329427055237	[305,492]	[31,71]	-4	dCas9-VP64	positive selection	2453163
43070007	43070030	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCGCAACCTCCGCCTCCCGGG	BRCA1	ENSG00000012048	-0.34420875558774866	[84,317]	[37,31]	-2	dCas9-VP64	positive selection	2460493
43107307	43107330	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCACTTTGGGAGGCAGAGGCGGG	BRCA1	ENSG00000012048	1.3055372672802243	[104,28]	[48,21]	5	dCas9-VP64	positive selection	2470072
43106074	43106097	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGCCACTGCACTCCAGCCTCAG	BRCA1	ENSG00000012048	0.6631647882125523	[138,30]	[44,11]	3	dCas9-VP64	positive selection	2473740
43066434	43066457	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAGTCTCACTCTGTCGCCAGG	BRCA1	ENSG00000012048	0.025453313513389197	[295,394]	[83,142]	0	dCas9-VP64	positive selection	2491031
43048353	43048376	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGCGTAGGGG	BRCA1	ENSG00000012048	0.01566490298595924	[8,84]	[11,17]	0	dCas9-VP64	positive selection	2500262
43123500	43123523	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGCGTAGTGG	BRCA1	ENSG00000012048	0.01566490298595924	[8,84]	[11,17]	0	dCas9-VP64	positive selection	2500290
43083387	43083410	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAAGTGATCAGCCCGCCTCGG	BRCA1	ENSG00000012048	-0.23923558367248954	[157,214]	[45,55]	-2	dCas9-VP64	positive selection	2522609
43067993	43068016	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGCCACCGCGCCCAGCCGAG	BRCA1	ENSG00000012048	-0.5349507089340686	[327,308]	[84,58]	-5	dCas9-VP64	positive selection	2533303
43124362	43124385	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCTGTAGCTTTCTCTTTCTTGG	BRCA1	ENSG00000012048	-0.3963732541253054	[149,169]	[62,16]	-4	dCas9-VP64	positive selection	2536769
43124376	43124399	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTACAGAGGAGTGACTGACCGG	BRCA1	ENSG00000012048	0.484592781110472	[76,92]	[56,20]	4	dCas9-VP64	positive selection	2536770
43124355	43124378	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTTTCTCTTTCTTGGAGAAAGG	BRCA1	ENSG00000012048	-0.2396891343726915	[183,89]	[64,12]	-2	dCas9-VP64	positive selection	2536771
43097490	43097513	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCCCAGCACTTGAG	BRCA1	ENSG00000012048	-0.7960951384238878	[400,199]	[64,47]	-7	dCas9-VP64	positive selection	2548418
43070007	43070030	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCGCAACCTCCGCCTCCCGGG	BRCA1	ENSG00000012048	-0.7693251235982987	[139,201]	[37,26]	-7	dCas9-VP64	positive selection	2555748
43107307	43107330	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCACTTTGGGAGGCAGAGGCGGG	BRCA1	ENSG00000012048	4.207282944889167	[182,227]	[2502,59]	9	dCas9-VP64	positive selection	2565327
43106074	43106097	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGCCACTGCACTCCAGCCTCAG	BRCA1	ENSG00000012048	-0.07877572482445189	[107,69]	[28,25]	0	dCas9-VP64	positive selection	2568995
43093898	43093921	17	+	27260157	DLD1	viability	CTTGACCATTCTGCTCCGTTTGG	BRCA1	ENSG00000012048	0.166243810671222	[]	[]	3	hSpCas9	negative selection	2573895
43106474	43106497	17	+	27260157	DLD1	viability	TTACATAAAGGACACTGTGAAGG	BRCA1	ENSG00000012048	-1.48640490727041	[]	[]	-8	hSpCas9	negative selection	2574210
43099843	43099866	17	-	27260157	DLD1	viability	AGTGTCCAACTCTCTAACCTTGG	BRCA1	ENSG00000012048	-1.3517427001037	[]	[]	-8	hSpCas9	negative selection	2576297
43106497	43106520	17	-	27260157	DLD1	viability	AACTTCTCAACCAGAAGAAAGGG	BRCA1	ENSG00000012048	-2.26548921742627	[]	[]	-9	hSpCas9	negative selection	2576910
43093659	43093682	17	+	27260157	DLD1	viability	TTCAAGCGCATGAATATGCCTGG	BRCA1	ENSG00000012048	-1.50288939693461	[]	[]	-8	hSpCas9	negative selection	2577180
43115763	43115786	17	-	27260157	DLD1	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-2.1378140101637	[]	[]	-9	hSpCas9	negative selection	2577459
43104931	43104954	17	+	27260157	DLD1	viability	TAAATCTCGTACTTTCTTGTAGG	BRCA1	ENSG00000012048	-2.85682201909268	[]	[]	-9	hSpCas9	negative selection	2578527
43093151	43093174	17	-	27260157	DLD1	viability	GGAAGTTAGCACTCTAGGGAAGG	BRCA1	ENSG00000012048	-1.0144300120582	[]	[]	-7	hSpCas9	negative selection	2582169
43106487	43106510	17	+	27260157	DLD1	viability	ACTGTGAAGGCCCTTTCTTCTGG	BRCA1	ENSG00000012048	-1.10625574870035	[]	[]	-7	hSpCas9	negative selection	2586773
43092103	43092126	17	+	27260157	DLD1	viability	GATGCATGACTACTTCCCATAGG	BRCA1	ENSG00000012048	-1.03464238605498	[]	[]	-7	hSpCas9	negative selection	2604260
43094118	43094141	17	+	27260157	DLD1	viability	GAGGCTTGCCTTCTTCCGATAGG	BRCA1	ENSG00000012048	-1.19674145060497	[]	[]	-7	hSpCas9	negative selection	2605449
43093190	43093213	17	-	27260157	DLD1	viability	TGGTACTGATTATGGCACTCAGG	BRCA1	ENSG00000012048	-1.94778941244225	[]	[]	-8	hSpCas9	negative selection	2615578
43092995	43093018	17	+	27260157	DLD1	viability	CTATGCTTGTTTCCCGACTGTGG	BRCA1	ENSG00000012048	-0.143035142169972	[]	[]	-1	hSpCas9	negative selection	2616677
43099851	43099874	17	+	27260157	DLD1	viability	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.822457904002304	[]	[]	9	hSpCas9	negative selection	2619816
43099838	43099861	17	+	27260157	DLD1	viability	CAGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-1.21508476327409	[]	[]	-7	hSpCas9	negative selection	2621222
43094578	43094601	17	+	27260157	DLD1	viability	TGTTGGCTCCTTGCTAAGCCAGG	BRCA1	ENSG00000012048	0.573406540535843	[]	[]	8	hSpCas9	negative selection	2623625
43094041	43094064	17	+	27260157	DLD1	viability	GGACGCTCTTGTATTATCTGTGG	BRCA1	ENSG00000012048	-2.32503571630791	[]	[]	-9	hSpCas9	negative selection	2624328
43104166	43104189	17	+	27260157	DLD1	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-2.64837140870474	[]	[]	-9	hSpCas9	negative selection	2642149
43106462	43106485	17	+	27260157	DLD1	viability	GTTATATCATTCTTACATAAAGG	BRCA1	ENSG00000012048	-0.805180224247973	[]	[]	-6	hSpCas9	negative selection	2644428
43104177	43104200	17	-	27260157	DLD1	viability	GTTTCTATCATCCAAAGTATGGG	BRCA1	ENSG00000012048	-1.13607283779779	[]	[]	-7	hSpCas9	negative selection	2649006
43093898	43093921	17	+	27260157	HT1080	viability	CTTGACCATTCTGCTCCGTTTGG	BRCA1	ENSG00000012048	-0.318632614579387	[]	[]	-7	hSpCas9	negative selection	2650025
43106474	43106497	17	+	27260157	HT1080	viability	TTACATAAAGGACACTGTGAAGG	BRCA1	ENSG00000012048	-1.104984762202	[]	[]	-8	hSpCas9	negative selection	2650340
43099843	43099866	17	-	27260157	HT1080	viability	AGTGTCCAACTCTCTAACCTTGG	BRCA1	ENSG00000012048	-2.02305659078373	[]	[]	-9	hSpCas9	negative selection	2652427
43106497	43106520	17	-	27260157	HT1080	viability	AACTTCTCAACCAGAAGAAAGGG	BRCA1	ENSG00000012048	-2.32245519917945	[]	[]	-9	hSpCas9	negative selection	2653040
43093659	43093682	17	+	27260157	HT1080	viability	TTCAAGCGCATGAATATGCCTGG	BRCA1	ENSG00000012048	-1.86295212896825	[]	[]	-9	hSpCas9	negative selection	2653310
43115763	43115786	17	-	27260157	HT1080	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-2.26623015552012	[]	[]	-9	hSpCas9	negative selection	2653589
43104931	43104954	17	+	27260157	HT1080	viability	TAAATCTCGTACTTTCTTGTAGG	BRCA1	ENSG00000012048	-4.60626193026245	[]	[]	-9	hSpCas9	negative selection	2654657
43093151	43093174	17	-	27260157	HT1080	viability	GGAAGTTAGCACTCTAGGGAAGG	BRCA1	ENSG00000012048	-0.664385141512615	[]	[]	-8	hSpCas9	negative selection	2658299
43106487	43106510	17	+	27260157	HT1080	viability	ACTGTGAAGGCCCTTTCTTCTGG	BRCA1	ENSG00000012048	-1.00854858706903	[]	[]	-8	hSpCas9	negative selection	2662903
43092103	43092126	17	+	27260157	HT1080	viability	GATGCATGACTACTTCCCATAGG	BRCA1	ENSG00000012048	-1.68213148401707	[]	[]	-9	hSpCas9	negative selection	2680390
43094118	43094141	17	+	27260157	HT1080	viability	GAGGCTTGCCTTCTTCCGATAGG	BRCA1	ENSG00000012048	-0.447550026520574	[]	[]	-7	hSpCas9	negative selection	2681579
43093190	43093213	17	-	27260157	HT1080	viability	TGGTACTGATTATGGCACTCAGG	BRCA1	ENSG00000012048	-2.72983108882762	[]	[]	-9	hSpCas9	negative selection	2691708
43092995	43093018	17	+	27260157	HT1080	viability	CTATGCTTGTTTCCCGACTGTGG	BRCA1	ENSG00000012048	-1.49826952231128	[]	[]	-9	hSpCas9	negative selection	2692807
43099851	43099874	17	+	27260157	HT1080	viability	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.0119413851087555	[]	[]	0	hSpCas9	negative selection	2695946
43099838	43099861	17	+	27260157	HT1080	viability	CAGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-1.95287039380791	[]	[]	-9	hSpCas9	negative selection	2697352
43094578	43094601	17	+	27260157	HT1080	viability	TGTTGGCTCCTTGCTAAGCCAGG	BRCA1	ENSG00000012048	0.696207595573675	[]	[]	6	hSpCas9	negative selection	2699755
43094041	43094064	17	+	27260157	HT1080	viability	GGACGCTCTTGTATTATCTGTGG	BRCA1	ENSG00000012048	-2.9411212473111	[]	[]	-9	hSpCas9	negative selection	2700458
43104166	43104189	17	+	27260157	HT1080	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-2.37294228811581	[]	[]	-9	hSpCas9	negative selection	2718279
43106462	43106485	17	+	27260157	HT1080	viability	GTTATATCATTCTTACATAAAGG	BRCA1	ENSG00000012048	-0.908424346470992	[]	[]	-8	hSpCas9	negative selection	2720558
43104177	43104200	17	-	27260157	HT1080	viability	GTTTCTATCATCCAAAGTATGGG	BRCA1	ENSG00000012048	-1.31339686041657	[]	[]	-9	hSpCas9	negative selection	2725136
43093898	43093921	17	+	27260157	MKN45	viability	CTTGACCATTCTGCTCCGTTTGG	BRCA1	ENSG00000012048	0.401576414781065	[]	[]	6	hSpCas9	negative selection	2726155
43106474	43106497	17	+	27260157	MKN45	viability	TTACATAAAGGACACTGTGAAGG	BRCA1	ENSG00000012048	-0.817035024565759	[]	[]	-7	hSpCas9	negative selection	2726470
43099843	43099866	17	-	27260157	MKN45	viability	AGTGTCCAACTCTCTAACCTTGG	BRCA1	ENSG00000012048	-1.21497046451723	[]	[]	-8	hSpCas9	negative selection	2728557
43106497	43106520	17	-	27260157	MKN45	viability	AACTTCTCAACCAGAAGAAAGGG	BRCA1	ENSG00000012048	-0.928954767139229	[]	[]	-7	hSpCas9	negative selection	2729170
43093659	43093682	17	+	27260157	MKN45	viability	TTCAAGCGCATGAATATGCCTGG	BRCA1	ENSG00000012048	-1.17810314216917	[]	[]	-8	hSpCas9	negative selection	2729440
43115763	43115786	17	-	27260157	MKN45	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.67485646780578	[]	[]	-9	hSpCas9	negative selection	2729719
43104931	43104954	17	+	27260157	MKN45	viability	TAAATCTCGTACTTTCTTGTAGG	BRCA1	ENSG00000012048	-2.79170599301232	[]	[]	-9	hSpCas9	negative selection	2730787
43093151	43093174	17	-	27260157	MKN45	viability	GGAAGTTAGCACTCTAGGGAAGG	BRCA1	ENSG00000012048	-0.89170037681177	[]	[]	-7	hSpCas9	negative selection	2734429
43106487	43106510	17	+	27260157	MKN45	viability	ACTGTGAAGGCCCTTTCTTCTGG	BRCA1	ENSG00000012048	-0.124199086497276	[]	[]	0	hSpCas9	negative selection	2739033
43092103	43092126	17	+	27260157	MKN45	viability	GATGCATGACTACTTCCCATAGG	BRCA1	ENSG00000012048	-1.56448867889954	[]	[]	-9	hSpCas9	negative selection	2756520
43094118	43094141	17	+	27260157	MKN45	viability	GAGGCTTGCCTTCTTCCGATAGG	BRCA1	ENSG00000012048	-1.19117368474748	[]	[]	-8	hSpCas9	negative selection	2757709
43093190	43093213	17	-	27260157	MKN45	viability	TGGTACTGATTATGGCACTCAGG	BRCA1	ENSG00000012048	-1.79291244466023	[]	[]	-9	hSpCas9	negative selection	2767838
43092995	43093018	17	+	27260157	MKN45	viability	CTATGCTTGTTTCCCGACTGTGG	BRCA1	ENSG00000012048	-0.918828912457643	[]	[]	-7	hSpCas9	negative selection	2768937
43099851	43099874	17	+	27260157	MKN45	viability	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	0.633220504112594	[]	[]	7	hSpCas9	negative selection	2772076
43099838	43099861	17	+	27260157	MKN45	viability	CAGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-1.06223417301703	[]	[]	-8	hSpCas9	negative selection	2773482
43094578	43094601	17	+	27260157	MKN45	viability	TGTTGGCTCCTTGCTAAGCCAGG	BRCA1	ENSG00000012048	1.44601694645797	[]	[]	9	hSpCas9	negative selection	2775885
43094041	43094064	17	+	27260157	MKN45	viability	GGACGCTCTTGTATTATCTGTGG	BRCA1	ENSG00000012048	-1.88272576516618	[]	[]	-9	hSpCas9	negative selection	2776588
43104166	43104189	17	+	27260157	MKN45	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-1.31868268990352	[]	[]	-8	hSpCas9	negative selection	2794409
43106462	43106485	17	+	27260157	MKN45	viability	GTTATATCATTCTTACATAAAGG	BRCA1	ENSG00000012048	-1.07510753855933	[]	[]	-8	hSpCas9	negative selection	2796688
43104177	43104200	17	-	27260157	MKN45	viability	GTTTCTATCATCCAAAGTATGGG	BRCA1	ENSG00000012048	-0.787448250008966	[]	[]	-7	hSpCas9	negative selection	2801266
43093898	43093921	17	+	27260157	RKO	viability	CTTGACCATTCTGCTCCGTTTGG	BRCA1	ENSG00000012048	-0.146837603644122	[]	[]	0	hSpCas9	negative selection	2802285
43106474	43106497	17	+	27260157	RKO	viability	TTACATAAAGGACACTGTGAAGG	BRCA1	ENSG00000012048	-2.70199318616896	[]	[]	-9	hSpCas9	negative selection	2802600
43099843	43099866	17	-	27260157	RKO	viability	AGTGTCCAACTCTCTAACCTTGG	BRCA1	ENSG00000012048	-1.25913518077314	[]	[]	-8	hSpCas9	negative selection	2804687
43106497	43106520	17	-	27260157	RKO	viability	AACTTCTCAACCAGAAGAAAGGG	BRCA1	ENSG00000012048	-1.26953248225659	[]	[]	-8	hSpCas9	negative selection	2805300
43093659	43093682	17	+	27260157	RKO	viability	TTCAAGCGCATGAATATGCCTGG	BRCA1	ENSG00000012048	-1.65502805092867	[]	[]	-9	hSpCas9	negative selection	2805570
43115763	43115786	17	-	27260157	RKO	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-3.24819623902493	[]	[]	-9	hSpCas9	negative selection	2805849
43104931	43104954	17	+	27260157	RKO	viability	TAAATCTCGTACTTTCTTGTAGG	BRCA1	ENSG00000012048	-3.12043643592756	[]	[]	-9	hSpCas9	negative selection	2806917
43093151	43093174	17	-	27260157	RKO	viability	GGAAGTTAGCACTCTAGGGAAGG	BRCA1	ENSG00000012048	-0.846735587557385	[]	[]	-7	hSpCas9	negative selection	2810559
43106487	43106510	17	+	27260157	RKO	viability	ACTGTGAAGGCCCTTTCTTCTGG	BRCA1	ENSG00000012048	-0.697269989156682	[]	[]	-7	hSpCas9	negative selection	2815163
43092103	43092126	17	+	27260157	RKO	viability	GATGCATGACTACTTCCCATAGG	BRCA1	ENSG00000012048	-2.10953182674061	[]	[]	-9	hSpCas9	negative selection	2832650
43094118	43094141	17	+	27260157	RKO	viability	GAGGCTTGCCTTCTTCCGATAGG	BRCA1	ENSG00000012048	-1.06758076668732	[]	[]	-8	hSpCas9	negative selection	2833839
43093190	43093213	17	-	27260157	RKO	viability	TGGTACTGATTATGGCACTCAGG	BRCA1	ENSG00000012048	-2.86408346748867	[]	[]	-9	hSpCas9	negative selection	2843968
43092995	43093018	17	+	27260157	RKO	viability	CTATGCTTGTTTCCCGACTGTGG	BRCA1	ENSG00000012048	0.0646028224342768	[]	[]	0	hSpCas9	negative selection	2845067
43099851	43099874	17	+	27260157	RKO	viability	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.654846053636403	[]	[]	-7	hSpCas9	negative selection	2848206
43099838	43099861	17	+	27260157	RKO	viability	CAGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-1.46271988387799	[]	[]	-8	hSpCas9	negative selection	2849612
43094578	43094601	17	+	27260157	RKO	viability	TGTTGGCTCCTTGCTAAGCCAGG	BRCA1	ENSG00000012048	0.660345479297078	[]	[]	3	hSpCas9	negative selection	2852015
43094041	43094064	17	+	27260157	RKO	viability	GGACGCTCTTGTATTATCTGTGG	BRCA1	ENSG00000012048	-1.35667521719375	[]	[]	-8	hSpCas9	negative selection	2852718
43104166	43104189	17	+	27260157	RKO	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-2.2955162272359	[]	[]	-9	hSpCas9	negative selection	2870539
43106462	43106485	17	+	27260157	RKO	viability	GTTATATCATTCTTACATAAAGG	BRCA1	ENSG00000012048	-2.8656554557858	[]	[]	-9	hSpCas9	negative selection	2872818
43104177	43104200	17	-	27260157	RKO	viability	GTTTCTATCATCCAAAGTATGGG	BRCA1	ENSG00000012048	-3.43007336018132	[]	[]	-9	hSpCas9	negative selection	2877396
43093898	43093921	17	+	27260157	SF268	viability	CTTGACCATTCTGCTCCGTTTGG	BRCA1	ENSG00000012048	-0.662605222035163	[]	[]	-5	hSpCas9	negative selection	2878415
43106474	43106497	17	+	27260157	SF268	viability	TTACATAAAGGACACTGTGAAGG	BRCA1	ENSG00000012048	-3.14432422739776	[]	[]	-9	hSpCas9	negative selection	2878730
43099843	43099866	17	-	27260157	SF268	viability	AGTGTCCAACTCTCTAACCTTGG	BRCA1	ENSG00000012048	-1.28626466885401	[]	[]	-7	hSpCas9	negative selection	2880817
43106497	43106520	17	-	27260157	SF268	viability	AACTTCTCAACCAGAAGAAAGGG	BRCA1	ENSG00000012048	-2.27129685593207	[]	[]	-9	hSpCas9	negative selection	2881430
43093659	43093682	17	+	27260157	SF268	viability	TTCAAGCGCATGAATATGCCTGG	BRCA1	ENSG00000012048	-1.71715592907521	[]	[]	-8	hSpCas9	negative selection	2881700
43115763	43115786	17	-	27260157	SF268	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-3.31875013072513	[]	[]	-9	hSpCas9	negative selection	2881979
43104931	43104954	17	+	27260157	SF268	viability	TAAATCTCGTACTTTCTTGTAGG	BRCA1	ENSG00000012048	-5.09307316811093	[]	[]	-9	hSpCas9	negative selection	2883047
43093151	43093174	17	-	27260157	SF268	viability	GGAAGTTAGCACTCTAGGGAAGG	BRCA1	ENSG00000012048	-2.01669750613939	[]	[]	-8	hSpCas9	negative selection	2886689
43106487	43106510	17	+	27260157	SF268	viability	ACTGTGAAGGCCCTTTCTTCTGG	BRCA1	ENSG00000012048	-1.58272815337956	[]	[]	-8	hSpCas9	negative selection	2891293
43092103	43092126	17	+	27260157	SF268	viability	GATGCATGACTACTTCCCATAGG	BRCA1	ENSG00000012048	-3.23660548758133	[]	[]	-9	hSpCas9	negative selection	2908780
43094118	43094141	17	+	27260157	SF268	viability	GAGGCTTGCCTTCTTCCGATAGG	BRCA1	ENSG00000012048	-1.2670287049105	[]	[]	-7	hSpCas9	negative selection	2909969
43093190	43093213	17	-	27260157	SF268	viability	TGGTACTGATTATGGCACTCAGG	BRCA1	ENSG00000012048	-3.41168015631896	[]	[]	-9	hSpCas9	negative selection	2920098
43092995	43093018	17	+	27260157	SF268	viability	CTATGCTTGTTTCCCGACTGTGG	BRCA1	ENSG00000012048	-1.74308722647403	[]	[]	-8	hSpCas9	negative selection	2921197
43099851	43099874	17	+	27260157	SF268	viability	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-1.07402551098302	[]	[]	-7	hSpCas9	negative selection	2924336
43099838	43099861	17	+	27260157	SF268	viability	CAGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-3.01561883135322	[]	[]	-9	hSpCas9	negative selection	2925742
43094578	43094601	17	+	27260157	SF268	viability	TGTTGGCTCCTTGCTAAGCCAGG	BRCA1	ENSG00000012048	0.735584024658049	[]	[]	8	hSpCas9	negative selection	2928145
43094041	43094064	17	+	27260157	SF268	viability	GGACGCTCTTGTATTATCTGTGG	BRCA1	ENSG00000012048	-1.49850579118431	[]	[]	-8	hSpCas9	negative selection	2928848
43104166	43104189	17	+	27260157	SF268	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-2.53841288383702	[]	[]	-9	hSpCas9	negative selection	2946669
43106462	43106485	17	+	27260157	SF268	viability	GTTATATCATTCTTACATAAAGG	BRCA1	ENSG00000012048	-2.97715460809899	[]	[]	-9	hSpCas9	negative selection	2948948
43104177	43104200	17	-	27260157	SF268	viability	GTTTCTATCATCCAAAGTATGGG	BRCA1	ENSG00000012048	-2.34322077330703	[]	[]	-9	hSpCas9	negative selection	2953526
43095876	43095899	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATCACCCCTCAAGGAACCAGGG	BRCA1	ENSG00000012048	-0.17915436289848213	[3,3]	[4,1]	-3	hSpCas9	positive selection	2973648
43099812	43099835	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.17605741056574126	[2,2]	[3,0]	-3	hSpCas9	positive selection	2973649
43106455	43106478	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAAGAATGATATAACCAAAAGG	BRCA1	ENSG00000012048	-1.4342091082343726	[1,2]	[0,0]	-9	hSpCas9	positive selection	2973650
43099827	43099850	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGAGTTCTCACAGTTCCAAGG	BRCA1	ENSG00000012048	-0.09687192880136652	[5,5]	[4,4]	-1	hSpCas9	positive selection	2973651
43095876	43095899	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATCACCCCTCAAGGAACCAGGG	BRCA1	ENSG00000012048	-0.580501016112686	[3,3]	[2,0]	-7	hSpCas9	positive selection	3041506
43099812	43099835	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.687071334702804	[2,2]	[1,0]	-8	hSpCas9	positive selection	3041507
43106455	43106478	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAAGAATGATATAACCAAAAGG	BRCA1	ENSG00000012048	0.26164271829969354	[1,1]	[2,0]	4	hSpCas9	positive selection	3041508
43099827	43099850	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGAGTTCTCACAGTTCCAAGG	BRCA1	ENSG00000012048	0.6748458419303827	[5,5]	[4,7]	9	hSpCas9	positive selection	3041509
43124016	43124039		-	24336571	A375	resistance to PLX after 7 days	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.2694257584478248	[46,44]	[55,53]	7	hSpCas9	positive selection	3150684
43091017	43091040		-	24336571	A375	resistance to PLX after 7 days	ATTTAAGGTGAAGCAGCATCTGG	BRCA1	ENSG00000012048	0.1324585003441007	[14,11]	[14,14]	4	hSpCas9	positive selection	3150693
43104166	43104189		+	24336571	A375	resistance to PLX after 7 days	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.17587589268868853	[10,11]	[11,13]	5	hSpCas9	positive selection	3150703
43115763	43115786		-	24336571	A375	resistance to PLX after 7 days	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	0.1470345263877027	[12,11]	[14,12]	5	hSpCas9	positive selection	3150711
43124016	43124039		-	24336571	A375	resistance to PLX after 14 days	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	1.3322983758595295	[34,60]	[55,55]	8	hSpCas9	positive selection	3208477
43091017	43091040		-	24336571	A375	resistance to PLX after 14 days	ATTTAAGGTGAAGCAGCATCTGG	BRCA1	ENSG00000012048	2.8154426769117684	[10,10]	[35,38]	9	hSpCas9	positive selection	3208486
43104166	43104189		+	24336571	A375	resistance to PLX after 14 days	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.4469154493247775	[8,7]	[5,4]	4	hSpCas9	positive selection	3208496
43115763	43115786		-	24336571	A375	resistance to PLX after 14 days	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.2311173995827989	[12,9]	[3,4]	-3	hSpCas9	positive selection	3208504
43124016	43124039		-	24336571	A375	viability after 7 days	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.07789099005370814	[50]	[46,44]	-1	hSpCas9	negative selection	3266270
43091017	43091040		-	24336571	A375	viability after 7 days	ATTTAAGGTGAAGCAGCATCTGG	BRCA1	ENSG00000012048	0.17126753886616336	[12]	[14,11]	2	hSpCas9	negative selection	3266279
43104166	43104189		+	24336571	A375	viability after 7 days	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.07759051520852016	[11]	[10,11]	1	hSpCas9	negative selection	3266289
43115763	43115786		-	24336571	A375	viability after 7 days	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.8988681383082175	[50]	[12,11]	-9	hSpCas9	negative selection	3266297
43124016	43124039		-	24336571	A375	viability after 14 days	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.00832454870253363	[50]	[34,60]	0	hSpCas9	negative selection	3324063
43091017	43091040		-	24336571	A375	viability after 14 days	ATTTAAGGTGAAGCAGCATCTGG	BRCA1	ENSG00000012048	-0.09704496252297755	[12]	[10,10]	-1	hSpCas9	negative selection	3324072
43104166	43104189		+	24336571	A375	viability after 14 days	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.3806465764776542	[11]	[8,7]	-4	hSpCas9	negative selection	3324082
43115763	43115786		-	24336571	A375	viability after 14 days	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.9850604480434069	[50]	[12,9]	-9	hSpCas9	negative selection	3324090
43115763	43115786	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	3.67629797834115	[6,16]	[0,0]	9	hSpCas9	positive selection	3339048
43124016	43124039	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.2512453661623913	[196,166]	[0,0]	-1	hSpCas9	positive selection	3339049
43104121	43104144	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-1.1886488398256931	[307,389]	[0,0]	-7	hSpCas9	positive selection	3339050
43104166	43104189	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.2818325996621964	[185,185]	[0,0]	-2	hSpCas9	positive selection	3358292
43115718	43115741	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	0.48914188666890873	[108,108]	[0,0]	2	hSpCas9	positive selection	3358293
43104178	43104201	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.06460188344152731	[159,159]	[0,0]	0	hSpCas9	positive selection	3358294
43095876	43095899	17	-	26780180	HT29	viability (Avana library 4 designs)	AATCACCCCTCAAGGAACCAGGG	BRCA1	ENSG00000012048	0.517065680010325	[]	[]	2	hSpCas9	negative selection	3409845
43099812	43099835	17	-	26780180	HT29	viability (Avana library 4 designs)	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	2.40887090556842	[]	[]	8	hSpCas9	negative selection	3409846
43106455	43106478	17	-	26780180	HT29	viability (Avana library 4 designs)	GTAAGAATGATATAACCAAAAGG	BRCA1	ENSG00000012048	2.66562260039795	[]	[]	8	hSpCas9	negative selection	3409847
43099826	43099849	17	+	26780180	HT29	viability (Avana library 4 designs)	TCAGAGTTCTCACAGTTCCAAGG	BRCA1	ENSG00000012048	2.80647010229297	[]	[]	8	hSpCas9	negative selection	3409848
43095876	43095899	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATCACCCCTCAAGGAACCAGGG	BRCA1	ENSG00000012048	-9.36832758690077	[]	[]	-7	hSpCas9	negative selection	3484059
43099812	43099835	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-4.39981586108794	[]	[]	-5	hSpCas9	negative selection	3484060
43106455	43106478	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAAGAATGATATAACCAAAAGG	BRCA1	ENSG00000012048	-24.572762095246	[]	[]	-9	hSpCas9	negative selection	3484061
43099826	43099849	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGAGTTCTCACAGTTCCAAGG	BRCA1	ENSG00000012048	-11.7009227514952	[]	[]	-8	hSpCas9	negative selection	3484062
43124001	43124024	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-9.35389269610583	[]	[]	-7	hSpCas9	negative selection	3484063
43097246	43097269	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAATAAGTTGCCTTATTAACGG	BRCA1	ENSG00000012048	-3.2099633153455	[]	[]	-4	hSpCas9	negative selection	3484064
43095876	43095899	17	-	26780180	A375	viability (Avana lentiGuide)	AATCACCCCTCAAGGAACCAGGG	BRCA1	ENSG00000012048	8.12501589990831	[]	[]	6	hSpCas9	negative selection	3592718
43099812	43099835	17	-	26780180	A375	viability (Avana lentiGuide)	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	0.471249439028805	[]	[]	0	hSpCas9	negative selection	3592719
43106455	43106478	17	-	26780180	A375	viability (Avana lentiGuide)	GTAAGAATGATATAACCAAAAGG	BRCA1	ENSG00000012048	25.3278984837603	[]	[]	9	hSpCas9	negative selection	3592720
43099826	43099849	17	+	26780180	A375	viability (Avana lentiGuide)	TCAGAGTTCTCACAGTTCCAAGG	BRCA1	ENSG00000012048	8.84823181718032	[]	[]	6	hSpCas9	negative selection	3592721
43124001	43124024	17	+	26780180	A375	viability (Avana lentiGuide)	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	18.1721430352573	[]	[]	8	hSpCas9	negative selection	3592722
43097246	43097269	17	+	26780180	A375	viability (Avana lentiGuide)	GCAATAAGTTGCCTTATTAACGG	BRCA1	ENSG00000012048	-7.07701260410063	[]	[]	-9	hSpCas9	negative selection	3592723
43095876	43095899	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCACCCCTCAAGGAACCAGGG	BRCA1	ENSG00000012048	-0.5574933477058966	[5]	[2,3]	-7	hSpCas9	positive selection	3701377
43099812	43099835	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.7895292231281862	[4]	[4,0]	-8	hSpCas9	positive selection	3701378
43106455	43106478	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAAGAATGATATAACCAAAAGG	BRCA1	ENSG00000012048	-1.1970445717925147	[7]	[2,2]	-9	hSpCas9	positive selection	3701379
43099826	43099849	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGAGTTCTCACAGTTCCAAGG	BRCA1	ENSG00000012048	-0.4353190851328639	[6]	[5,4]	-6	hSpCas9	positive selection	3701380
43124001	43124024	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-0.24499663135642538	[6]	[5,4]	-4	hSpCas9	positive selection	3701381
43097246	43097269	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAATAAGTTGCCTTATTAACGG	BRCA1	ENSG00000012048	-0.1707952069546151	[7]	[5,5]	-3	hSpCas9	positive selection	3701382
43095876	43095899	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCACCCCTCAAGGAACCAGGG	BRCA1	ENSG00000012048	-0.09096202263022289	[5]	[2,5]	-1	hSpCas9	positive selection	3809984
43099812	43099835	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-1.149640945649774	[4]	[1,0]	-8	hSpCas9	positive selection	3809985
43106455	43106478	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAAGAATGATATAACCAAAAGG	BRCA1	ENSG00000012048	-1.5599589576575137	[3]	[0,0]	-9	hSpCas9	positive selection	3809986
43099826	43099849	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGAGTTCTCACAGTTCCAAGG	BRCA1	ENSG00000012048	0.05584189205842205	[7]	[6,6]	1	hSpCas9	positive selection	3809987
43124001	43124024	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-0.18108451087553265	[7]	[4,5]	-3	hSpCas9	positive selection	3809988
43097246	43097269	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAATAAGTTGCCTTATTAACGG	BRCA1	ENSG00000012048	0.18129091843335315	[4]	[3,4]	4	hSpCas9	positive selection	3809989
43115718	43115741	17	+	26780180	A375	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	1.39069644319591	[]	[]	7	hSpCas9	negative selection	3918240
43124016	43124039	17	-	26780180	A375	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	1.37902985710448	[]	[]	7	hSpCas9	negative selection	3918241
43104178	43104201	17	-	26780180	A375	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	1.06743548691035	[]	[]	5	hSpCas9	negative selection	3918242
43104166	43104189	17	+	26780180	A375	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	1.38744996993454	[]	[]	7	hSpCas9	negative selection	3918243
43104121	43104144	17	-	26780180	A375	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	1.42000046269978	[]	[]	7	hSpCas9	negative selection	3918244
43115763	43115786	17	-	26780180	A375	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	1.05468728020934	[]	[]	5	hSpCas9	negative selection	3918245
43115718	43115741	17	+	26780180	HT29	viability (GeCKOv2 library)	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	2.16932692253177	[]	[]	9	hSpCas9	negative selection	4026206
43124016	43124039	17	-	26780180	HT29	viability (GeCKOv2 library)	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	1.23084304136178	[]	[]	6	hSpCas9	negative selection	4026207
43104178	43104201	17	-	26780180	HT29	viability (GeCKOv2 library)	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	1.05095328570846	[]	[]	5	hSpCas9	negative selection	4026208
43104166	43104189	17	+	26780180	HT29	viability (GeCKOv2 library)	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	1.61374126699597	[]	[]	8	hSpCas9	negative selection	4026209
43104121	43104144	17	-	26780180	HT29	viability (GeCKOv2 library)	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.464844775753005	[]	[]	1	hSpCas9	negative selection	4026210
43115763	43115786	17	-	26780180	HT29	viability (GeCKOv2 library)	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	1.31743233981807	[]	[]	6	hSpCas9	negative selection	4026211
43124016	43124039	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.31503929783565326	[5]	[3,5]	7	hSpCas9	positive selection	4177102
43091017	43091040	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTTAAGGTGAAGCAGCATCTGG	BRCA1	ENSG00000012048	0.5327996886849456	[3]	[2,5]	9	hSpCas9	positive selection	4177113
43104166	43104189	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.15059673215633676	[2]	[1,2]	4	hSpCas9	positive selection	4177124
43115763	43115786	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.188454094967313	[4]	[2,1]	-4	hSpCas9	positive selection	4177134
43124016	43124039	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.4353155141193198	[5]	[2,1,1,0]	-6	hSpCas9	positive selection	4241124
43091017	43091040	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTTAAGGTGAAGCAGCATCTGG	BRCA1	ENSG00000012048	0.35438689072311114	[1]	[0,2,0,0]	2	hSpCas9	positive selection	4241135
43104166	43104189	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.2752161515232229	[1]	[3,0,0,0]	2	hSpCas9	positive selection	4241146
43115763	43115786	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.8106738928019463	[5]	[0,2,0,0]	-9	hSpCas9	positive selection	4241156
43115763	43115786	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.8527820926068315	[1]	[0,0]	-9	hSpCas9	positive selection	4258462
43124016	43124039	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.22368434585984967	[3]	[3,1]	-4	hSpCas9	positive selection	4258463
43104121	43104144	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.016902492401554614	[4]	[3,2]	0	hSpCas9	positive selection	4258464
43104166	43104189	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.24778182674003246	[3]	[2,2]	5	hSpCas9	positive selection	4322746
43115718	43115741	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.4167489431628779	[2]	[1,1]	-7	hSpCas9	positive selection	4322747
43104178	43104201	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.37265800332641497	[3]	[2,0]	-7	hSpCas9	positive selection	4322748
43095860	43095882	17	+	27760321	OCIAML3	viability	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.4240070429733953	[490,365]	[400,503]	5	hSpCas9	negative selection	4382189
43095884	43095906	17	-	27760321	OCIAML3	viability	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	0.06633130165246692	[181,163]	[144,136]	0	hSpCas9	negative selection	4382190
43097257	43097279	17	-	27760321	OCIAML3	viability	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-3.1308651996382055	[8,12]	[0,0]	-9	hSpCas9	negative selection	4382191
43099839	43099861	17	+	27760321	OCIAML3	viability	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-0.07740731593454542	[132,151]	[96,118]	-1	hSpCas9	negative selection	4382192
43104146	43104168	17	+	27760321	OCIAML3	viability	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.15964186959290855	[441,431]	[330,449]	1	hSpCas9	negative selection	4382193
43095860	43095882	17	+	27760321	OCIAML2	viability	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.03947916932354665	[490,365]	[287,438]	0	hSpCas9	negative selection	4465652
43095884	43095906	17	-	27760321	OCIAML2	viability	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	-0.31407421980817296	[181,163]	[86,145]	-4	hSpCas9	negative selection	4465653
43097257	43097279	17	-	27760321	OCIAML2	viability	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-0.494447400971616	[8,12]	[5,6]	-5	hSpCas9	negative selection	4465654
43099839	43099861	17	+	27760321	OCIAML2	viability	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-0.7139036731138424	[132,151]	[85,50]	-6	hSpCas9	negative selection	4465655
43104146	43104168	17	+	27760321	OCIAML2	viability	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.5263605526849889	[441,431]	[436,606]	7	hSpCas9	negative selection	4465656
43095860	43095882	17	+	27760321	MV411	viability	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	-0.3014279560757703	[490,365]	[55,484]	-2	hSpCas9	negative selection	4549115
43095884	43095906	17	-	27760321	MV411	viability	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	0.8120041091740905	[181,163]	[238,141]	6	hSpCas9	negative selection	4549116
43097257	43097279	17	-	27760321	MV411	viability	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-2.8857866307235236	[8,12]	[0,0]	-9	hSpCas9	negative selection	4549117
43099839	43099861	17	+	27760321	MV411	viability	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-0.4029856168035362	[132,151]	[0,177]	-3	hSpCas9	negative selection	4549118
43104146	43104168	17	+	27760321	MV411	viability	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	-0.06891223399069796	[441,431]	[239,328]	0	hSpCas9	negative selection	4549119
43095860	43095882	17	+	27760321	HL60	viability	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.6539492072091335	[490,365]	[710,370]	7	hSpCas9	negative selection	4632578
43095884	43095906	17	-	27760321	HL60	viability	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	1.052536498245024	[181,163]	[336,245]	9	hSpCas9	negative selection	4632579
43097257	43097279	17	-	27760321	HL60	viability	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-3.19365679251766	[8,12]	[0,0]	-9	hSpCas9	negative selection	4632580
43099839	43099861	17	+	27760321	HL60	viability	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-0.285102365964244	[132,151]	[91,100]	-3	hSpCas9	negative selection	4632581
43104146	43104168	17	+	27760321	HL60	viability	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.12777958505117468	[441,431]	[438,339]	1	hSpCas9	negative selection	4632582
43095860	43095882	17	+	27760321	HT1080	viability	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	-1.1834640449245408	[365,285]	[39,75]	-5	hSpCas9	negative selection	4716041
43095884	43095906	17	-	27760321	HT1080	viability	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	-0.0945178852968247	[163,127]	[74,31]	0	hSpCas9	negative selection	4716042
43097257	43097279	17	-	27760321	HT1080	viability	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-2.194450976201537	[12,9]	[0,0]	-6	hSpCas9	negative selection	4716043
43099839	43099861	17	+	27760321	HT1080	viability	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-5.754609744218425	[151,118]	[0,0]	-8	hSpCas9	negative selection	4716044
43104146	43104168	17	+	27760321	HT1080	viability	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.11878195744255567	[431,336]	[193,135]	0	hSpCas9	negative selection	4716045
43095860	43095882	17	+	27760321	HT29	viability after 7 days	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.4071435297558834	[365,285]	[590,500,578]	6	hSpCas9	negative selection	4799504
43095884	43095906	17	-	27760321	HT29	viability after 7 days	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	-0.22584232200188326	[163,127]	[222,67,197]	-3	hSpCas9	negative selection	4799505
43097257	43097279	17	-	27760321	HT29	viability after 7 days	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-3.1253259845040544	[12,9]	[0,2,0]	-9	hSpCas9	negative selection	4799506
43099839	43099861	17	+	27760321	HT29	viability after 7 days	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-0.4964312654275269	[151,118]	[110,178,79]	-6	hSpCas9	negative selection	4799507
43104146	43104168	17	+	27760321	HT29	viability after 7 days	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.5178201723112521	[431,336]	[781,676,674]	7	hSpCas9	negative selection	4799508
43095860	43095882	17	+	27760321	HT29	viability after 25 days	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.08733067427021496	[365,285]	[305,331,572]	0	hSpCas9	negative selection	4882967
43095884	43095906	17	-	27760321	HT29	viability after 25 days	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	-0.592829389499111	[163,127]	[139,103,82]	-5	hSpCas9	negative selection	4882968
43097257	43097279	17	-	27760321	HT29	viability after 25 days	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-0.45143100414362536	[12,9]	[7,18,0]	-4	hSpCas9	negative selection	4882969
43099839	43099861	17	+	27760321	HT29	viability after 25 days	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-1.3774420231568618	[151,118]	[43,47,90]	-7	hSpCas9	negative selection	4882970
43104146	43104168	17	+	27760321	HT29	viability after 25 days	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.28765406323462867	[431,336]	[480,462,682]	3	hSpCas9	negative selection	4882971
43095860	43095882	17	+	27760321	HT29	viability after 22 days	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.2861122896005328	[365,285]	[527,373,474]	3	hSpCas9	negative selection	4966430
43095884	43095906	17	-	27760321	HT29	viability after 22 days	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	-0.17687535899448048	[163,127]	[83,287,76]	-2	hSpCas9	negative selection	4966431
43097257	43097279	17	-	27760321	HT29	viability after 22 days	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-3.7314518729073205	[12,9]	[0,0,0]	-9	hSpCas9	negative selection	4966432
43099839	43099861	17	+	27760321	HT29	viability after 22 days	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-1.2958174587264144	[151,118]	[82,35,71]	-7	hSpCas9	negative selection	4966433
43104146	43104168	17	+	27760321	HT29	viability after 22 days	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.5238253950297301	[431,336]	[534,535,850]	6	hSpCas9	negative selection	4966434
43095860	43095882	17	+	27760321	HT29	viability after 19 days	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.12802164137351113	[365,285]	[315,393,498]	1	hSpCas9	negative selection	5049893
43095884	43095906	17	-	27760321	HT29	viability after 19 days	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	-0.1379396034677074	[163,127]	[124,192,134]	-1	hSpCas9	negative selection	5049894
43097257	43097279	17	-	27760321	HT29	viability after 19 days	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-3.7156118204841073	[12,9]	[0,0,0]	-9	hSpCas9	negative selection	5049895
43099839	43099861	17	+	27760321	HT29	viability after 19 days	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-2.8796622709152535	[151,118]	[46,0,17]	-8	hSpCas9	negative selection	5049896
43104146	43104168	17	+	27760321	HT29	viability after 19 days	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	1.269915776749449	[431,336]	[626,1283,1217]	9	hSpCas9	negative selection	5049897
43095860	43095882	17	+	27760321	HT29	viability after 16 days	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.6008284745650827	[365,285]	[484,630,534]	7	hSpCas9	negative selection	5133356
43095884	43095906	17	-	27760321	HT29	viability after 16 days	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	-0.7741880230284173	[163,127]	[121,57,109]	-6	hSpCas9	negative selection	5133357
43097257	43097279	17	-	27760321	HT29	viability after 16 days	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-3.6841473680631855	[12,9]	[0,0,0]	-9	hSpCas9	negative selection	5133358
43099839	43099861	17	+	27760321	HT29	viability after 16 days	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-0.9418124610358347	[151,118]	[117,58,63]	-7	hSpCas9	negative selection	5133359
43104146	43104168	17	+	27760321	HT29	viability after 16 days	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.7454996753474101	[431,336]	[725,871,561]	8	hSpCas9	negative selection	5133360
43095860	43095882	17	+	27760321	HT29	viability after 13 days	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.3247664506014948	[365,285]	[429,514,475]	4	hSpCas9	negative selection	5216819
43095884	43095906	17	-	27760321	HT29	viability after 13 days	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	0.14794408054505181	[163,127]	[366,151,51]	1	hSpCas9	negative selection	5216820
43097257	43097279	17	-	27760321	HT29	viability after 13 days	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-3.7364347675073235	[12,9]	[0,0,0]	-9	hSpCas9	negative selection	5216821
43099839	43099861	17	+	27760321	HT29	viability after 13 days	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-1.0148440828425203	[151,118]	[84,97,51]	-7	hSpCas9	negative selection	5216822
43104146	43104168	17	+	27760321	HT29	viability after 13 days	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.7305487299790603	[431,336]	[778,630,805]	8	hSpCas9	negative selection	5216823
43095860	43095882	17	+	27760321	HT29	viability after 10 days	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.2744565083194266	[365,285]	[567,518,392]	3	hSpCas9	negative selection	5300282
43095884	43095906	17	-	27760321	HT29	viability after 10 days	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	0.4536309894505971	[163,127]	[280,277,191]	6	hSpCas9	negative selection	5300283
43097257	43097279	17	-	27760321	HT29	viability after 10 days	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-2.849254834279437	[12,9]	[0,2,1]	-9	hSpCas9	negative selection	5300284
43099839	43099861	17	+	27760321	HT29	viability after 10 days	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-1.0166354183617032	[151,118]	[127,105,18]	-8	hSpCas9	negative selection	5300285
43104146	43104168	17	+	27760321	HT29	viability after 10 days	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	0.06501538271948316	[431,336]	[487,438,575]	0	hSpCas9	negative selection	5300286
43095860	43095882	17	+	27760321	MOLM13	viability	TCCAAACTGATTTCATCCCTGG	BRCA1	ENSG00000012048	0.1678531159138945	[490,365]	[514,59]	1	hSpCas9	negative selection	5383745
43095884	43095906	17	-	27760321	MOLM13	viability	TGTTACAAATCACCCCTCAAGG	BRCA1	ENSG00000012048	0.7072165405578846	[181,163]	[95,212]	5	hSpCas9	negative selection	5383746
43097257	43097279	17	-	27760321	MOLM13	viability	TCTGAAGATACCGTTAATAAGG	BRCA1	ENSG00000012048	-2.6597298178959283	[8,12]	[0,0]	-8	hSpCas9	negative selection	5383747
43099839	43099861	17	+	27760321	MOLM13	viability	AGTTCCAAGGTTAGAGAGTTGG	BRCA1	ENSG00000012048	-2.4898865336666187	[132,151]	[21,7]	-8	hSpCas9	negative selection	5383748
43104146	43104168	17	+	27760321	MOLM13	viability	CTGTAGAAGTCTTTTGGCACGG	BRCA1	ENSG00000012048	-0.5815471693833208	[441,431]	[216,120]	-4	hSpCas9	negative selection	5383749
43125116	43125139	17	-	27661255	K562	viability	GGCGTTGTGAACCCTGGGGAGGG	BRCA1	ENSG00000012048	-0.2995977939943034	[1067,932]	[658,643]	-7	dCas9-KRAB	negative selection	5465467
43115763	43115786	17	-	27260156	BXPC3	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.9889954607720481	[101]	[41,41,70,62]	-9	hSpCas9	negative selection	5530922
43124016	43124039	17	-	27260156	BXPC3	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.061322046387478846	[797]	[728,730,851,906]	-1	hSpCas9	negative selection	5530923
43104121	43104144	17	-	27260156	BXPC3	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.019055393432519496	[1154]	[907,1227,1188,1500]	0	hSpCas9	negative selection	5530924
43104166	43104189	17	+	27260156	BXPC3	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.02067897326284429	[486]	[439,459,617,563]	0	hSpCas9	negative selection	5595206
43115718	43115741	17	+	27260156	BXPC3	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.43651708620118757	[444]	[318,365,321,369]	-7	hSpCas9	negative selection	5595207
43104178	43104201	17	-	27260156	BXPC3	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.20178906342111405	[468]	[394,365,467,488]	-4	hSpCas9	negative selection	5595208
43115763	43115786	17	-	27260156	A673	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.3663357409466808	[101]	[53,36,50,48]	-9	hSpCas9	negative selection	5652173
43124016	43124039	17	-	27260156	A673	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.27948523669283615	[797]	[887,690,742,851]	-6	hSpCas9	negative selection	5652174
43104121	43104144	17	-	27260156	A673	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.16835739581549358	[1154]	[1281,1097,1358,1200]	-4	hSpCas9	negative selection	5652175
43104166	43104189	17	+	27260156	A673	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.16572099462457618	[486]	[525,513,506,538]	-4	hSpCas9	negative selection	5716457
43115718	43115741	17	+	27260156	A673	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.5779352380845714	[444]	[365,392,321,349]	-8	hSpCas9	negative selection	5716458
43104178	43104201	17	-	27260156	A673	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.12397720168327533	[468]	[534,551,517,458]	-3	hSpCas9	negative selection	5716459
43115763	43115786	17	-	27260156	A375	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-3.0214213775206593	[101]	[13,43,1,3]	-9	hSpCas9	negative selection	5773424
43124016	43124039	17	-	27260156	A375	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.5747540268654059	[797]	[839,835,483,398]	-6	hSpCas9	negative selection	5773425
43104121	43104144	17	-	27260156	A375	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.3737856638528442	[1154]	[1030,1030,1074,1023]	-5	hSpCas9	negative selection	5773426
43104166	43104189	17	+	27260156	A375	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.24119582134201978	[486]	[452,706,439,367]	-3	hSpCas9	negative selection	5837708
43115718	43115741	17	+	27260156	A375	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.3524094891855605	[444]	[399,363,432,421]	-5	hSpCas9	negative selection	5837709
43104178	43104201	17	-	27260156	A375	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.6097085062439419	[468]	[331,344,318,427]	-7	hSpCas9	negative selection	5837710
43115763	43115786	17	-	27260156	COLO741	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.8540992341524922	[101]	[58,138,20]	-9	hSpCas9	negative selection	5894675
43124016	43124039	17	-	27260156	COLO741	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.41755736218027534	[797]	[775,910,613]	-7	hSpCas9	negative selection	5894676
43104121	43104144	17	-	27260156	COLO741	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.08559585592030028	[1154]	[1540,1636,1517]	1	hSpCas9	negative selection	5894677
43104166	43104189	17	+	27260156	COLO741	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.21913326465797128	[486]	[554,581,471]	-5	hSpCas9	negative selection	5958959
43115718	43115741	17	+	27260156	COLO741	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.7290023942580395	[444]	[493,261,288]	-9	hSpCas9	negative selection	5958960
43104178	43104201	17	-	27260156	COLO741	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.14474671463913763	[468]	[659,520,459]	-3	hSpCas9	negative selection	5958961
43115763	43115786	17	-	27260156	CAL120	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-2.6705605020024095	[101]	[3,10,41]	-9	hSpCas9	negative selection	6015926
43124016	43124039	17	-	27260156	CAL120	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.06771109727099023	[797]	[920,572,1336]	-1	hSpCas9	negative selection	6015927
43104121	43104144	17	-	27260156	CAL120	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.28193183571195335	[1154]	[1143,1203,1191]	-4	hSpCas9	negative selection	6015928
43104166	43104189	17	+	27260156	CAL120	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.035077486397376734	[486]	[642,553,667]	0	hSpCas9	negative selection	6080210
43115718	43115741	17	+	27260156	CAL120	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.09593161172810326	[444]	[556,427,573]	-1	hSpCas9	negative selection	6080211
43104178	43104201	17	-	27260156	CAL120	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.053346598784977696	[468]	[665,605,432]	-1	hSpCas9	negative selection	6080212
43115763	43115786	17	-	27260156	CADOES1	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-2.086288239604265	[101]	[16,30,28,11]	-9	hSpCas9	negative selection	6137177
43124016	43124039	17	-	27260156	CADOES1	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.13263957647649405	[797]	[701,589,877,1094]	2	hSpCas9	negative selection	6137178
43104121	43104144	17	-	27260156	CADOES1	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.030202766660847313	[1154]	[1011,942,1039,1218]	0	hSpCas9	negative selection	6137179
43104166	43104189	17	+	27260156	CADOES1	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.044514536649011865	[486]	[379,461,424,606]	0	hSpCas9	negative selection	6201461
43115718	43115741	17	+	27260156	CADOES1	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.28650503702180263	[444]	[222,396,314,425]	-5	hSpCas9	negative selection	6201462
43104178	43104201	17	-	27260156	CADOES1	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.1580018153457701	[468]	[387,326,346,505]	-3	hSpCas9	negative selection	6201463
43115763	43115786	17	-	27260156	EWS502	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.8877819260374027	[101]	[38,56,0,15]	-9	hSpCas9	negative selection	6258428
43124016	43124039	17	-	27260156	EWS502	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.23149207742235	[797]	[716,580,785,805]	-4	hSpCas9	negative selection	6258429
43104121	43104144	17	-	27260156	EWS502	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.059523931742169855	[1154]	[1062,1184,1019,1453]	-1	hSpCas9	negative selection	6258430
43104166	43104189	17	+	27260156	EWS502	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.1575742530001295	[486]	[581,561,578,575]	2	hSpCas9	negative selection	6322712
43115718	43115741	17	+	27260156	EWS502	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.24707457184301684	[444]	[275,340,668,315]	-4	hSpCas9	negative selection	6322713
43104178	43104201	17	-	27260156	EWS502	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.2902315964232507	[468]	[356,381,508,381]	-5	hSpCas9	negative selection	6322714
43115763	43115786	17	-	27260156	EW8	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.0412180645203373	[101]	[39,53,7,63]	-9	hSpCas9	negative selection	6379679
43124016	43124039	17	-	27260156	EW8	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.11172681396551243	[797]	[756,580,442,654]	-2	hSpCas9	negative selection	6379680
43104121	43104144	17	-	27260156	EW8	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.02998267699209789	[1154]	[992,1067,707,939]	0	hSpCas9	negative selection	6379681
43104166	43104189	17	+	27260156	EW8	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.107983115243353	[486]	[400,292,264,524]	-2	hSpCas9	negative selection	6443963
43115718	43115741	17	+	27260156	EW8	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.497932838779673	[444]	[244,323,231,222]	-7	hSpCas9	negative selection	6443964
43104178	43104201	17	-	27260156	EW8	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.1947451080846737	[468]	[249,378,370,311]	-4	hSpCas9	negative selection	6443965
43115763	43115786	17	-	27260156	CORL105	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.170993132664297	[101]	[56,53,38,59]	-9	hSpCas9	negative selection	6500930
43124016	43124039	17	-	27260156	CORL105	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.20736808228819237	[797]	[710,885,894,752]	-4	hSpCas9	negative selection	6500931
43104121	43104144	17	-	27260156	CORL105	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.20228221236698896	[1154]	[1204,1015,1342,1166]	-4	hSpCas9	negative selection	6500932
43104166	43104189	17	+	27260156	CORL105	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.5319529117166363	[486]	[325,399,491,371]	-7	hSpCas9	negative selection	6565214
43115718	43115741	17	+	27260156	CORL105	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-1.083631690780541	[444]	[267,179,276,264]	-9	hSpCas9	negative selection	6565215
43104178	43104201	17	-	27260156	CORL105	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.5948052969600276	[468]	[357,372,477,262]	-8	hSpCas9	negative selection	6565216
43115763	43115786	17	-	27260156	HS294T	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.7727093706788843	[101]	[2,2,15,27]	-9	hSpCas9	negative selection	6622181
43124016	43124039	17	-	27260156	HS294T	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.053777495874073655	[797]	[328,259,382,306]	0	hSpCas9	negative selection	6622182
43104121	43104144	17	-	27260156	HS294T	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.06457270065136966	[1154]	[366,384,499,468]	-1	hSpCas9	negative selection	6622183
43104166	43104189	17	+	27260156	HS294T	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.12779297752147661	[486]	[259,152,148,266]	1	hSpCas9	negative selection	6686465
43115718	43115741	17	+	27260156	HS294T	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.6912167273082037	[444]	[93,111,98,124]	-7	hSpCas9	negative selection	6686466
43104178	43104201	17	-	27260156	HS294T	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.8210126853216692	[468]	[74,58,159,123]	-8	hSpCas9	negative selection	6686467
43115763	43115786	17	-	27260156	HCC44	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-4.343284055917469	[101]	[6,0,13,2]	-9	hSpCas9	negative selection	6743432
43124016	43124039	17	-	27260156	HCC44	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.146704850356285	[797]	[951,698,973,689]	-2	hSpCas9	negative selection	6743433
43104121	43104144	17	-	27260156	HCC44	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.027946640200877004	[1154]	[1281,1070,1832,1060]	0	hSpCas9	negative selection	6743434
43104166	43104189	17	+	27260156	HCC44	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.14719701802544238	[486]	[725,247,509,557]	-2	hSpCas9	negative selection	6807716
43115718	43115741	17	+	27260156	HCC44	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.46726505575507904	[444]	[401,261,430,386]	-6	hSpCas9	negative selection	6807717
43104178	43104201	17	-	27260156	HCC44	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	0.0017289695918947955	[468]	[732,405,597,433]	0	hSpCas9	negative selection	6807718
43115763	43115786	17	-	27260156	G402	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-3.7392536265431486	[101]	[20,5,7,3]	-9	hSpCas9	negative selection	6864683
43124016	43124039	17	-	27260156	G402	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.14970236357470357	[797]	[1320,944,838,1230]	2	hSpCas9	negative selection	6864684
43104121	43104144	17	-	27260156	G402	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.28663953365156525	[1154]	[1181,915,675,1800]	-4	hSpCas9	negative selection	6864685
43104166	43104189	17	+	27260156	G402	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.1270542243109341	[486]	[532,741,484,429]	-2	hSpCas9	negative selection	6928967
43115718	43115741	17	+	27260156	G402	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.9287194403806861	[444]	[339,236,367,203]	-8	hSpCas9	negative selection	6928968
43104178	43104201	17	-	27260156	G402	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.4904420181331192	[468]	[461,110,521,517]	-6	hSpCas9	negative selection	6928969
43115763	43115786	17	-	27260156	L33	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	0.03751629646873367	[101]	[100,43,64,106]	0	hSpCas9	negative selection	6985934
43124016	43124039	17	-	27260156	L33	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.12132952694001542	[797]	[872,306,506,1040]	2	hSpCas9	negative selection	6985935
43104121	43104144	17	-	27260156	L33	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.4328911577063159	[1154]	[1410,569,1072,1729]	8	hSpCas9	negative selection	6985936
43104166	43104189	17	+	27260156	L33	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.22884216586482647	[486]	[543,185,416,621]	5	hSpCas9	negative selection	7050218
43115718	43115741	17	+	27260156	L33	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.10494406722518042	[444]	[345,152,283,484]	-2	hSpCas9	negative selection	7050219
43104178	43104201	17	-	27260156	L33	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.17465879533172837	[468]	[412,153,298,397]	-4	hSpCas9	negative selection	7050220
43115763	43115786	17	-	27260156	K562	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.4504586389739549	[101]	[33,54,24,20]	-9	hSpCas9	negative selection	7107185
43124016	43124039	17	-	27260156	K562	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.06768076540147594	[797]	[683,867,560,605]	-1	hSpCas9	negative selection	7107186
43104121	43104144	17	-	27260156	K562	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.14562312100598174	[1154]	[883,1580,867,455]	-2	hSpCas9	negative selection	7107187
43104166	43104189	17	+	27260156	K562	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.2977819185306145	[486]	[654,347,463,642]	4	hSpCas9	negative selection	7171469
43115718	43115741	17	+	27260156	K562	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.19411707147982127	[444]	[382,437,246,321]	-2	hSpCas9	negative selection	7171470
43104178	43104201	17	-	27260156	K562	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.07509183737164746	[468]	[295,470,293,500]	-1	hSpCas9	negative selection	7171471
43115763	43115786	17	-	27260156	HT29	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-2.2884536165745315	[101]	[35,22,26,16]	-9	hSpCas9	negative selection	7228436
43124016	43124039	17	-	27260156	HT29	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.304736162646502	[797]	[828,938,641,746]	-5	hSpCas9	negative selection	7228437
43104121	43104144	17	-	27260156	HT29	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.2600236102751763	[1154]	[1421,1289,1134,897]	-5	hSpCas9	negative selection	7228438
43104166	43104189	17	+	27260156	HT29	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.08209829762471411	[486]	[774,669,649,444]	1	hSpCas9	negative selection	7292720
43115718	43115741	17	+	27260156	HT29	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.9555026686936342	[444]	[366,214,217,310]	-8	hSpCas9	negative selection	7292721
43104178	43104201	17	-	27260156	HT29	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.37283415170882156	[468]	[521,424,555,279]	-6	hSpCas9	negative selection	7292722
43115763	43115786	17	-	27260156	MHHES1	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.979112135381615	[101]	[67,54,1,3]	-9	hSpCas9	negative selection	7349687
43124016	43124039	17	-	27260156	MHHES1	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.048177460274902884	[797]	[865,827,1059,731]	-1	hSpCas9	negative selection	7349688
43104121	43104144	17	-	27260156	MHHES1	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.11651177325980444	[1154]	[1288,1178,1143,1173]	-2	hSpCas9	negative selection	7349689
43104166	43104189	17	+	27260156	MHHES1	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.05033101666423738	[486]	[1101,308,552,377]	0	hSpCas9	negative selection	7413971
43115718	43115741	17	+	27260156	MHHES1	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.6954946896325463	[444]	[223,402,415,210]	-8	hSpCas9	negative selection	7413972
43104178	43104201	17	-	27260156	MHHES1	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.3809709087186179	[468]	[516,387,398,336]	-6	hSpCas9	negative selection	7413973
43115763	43115786	17	-	27260156	MEWO	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.48991526767417337	[101]	[58,88,53]	-8	hSpCas9	negative selection	7470938
43124016	43124039	17	-	27260156	MEWO	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.3800569987280292	[797]	[757,493,504]	-7	hSpCas9	negative selection	7470939
43104121	43104144	17	-	27260156	MEWO	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.07126123920258731	[1154]	[1340,1025,1078]	1	hSpCas9	negative selection	7470940
43104166	43104189	17	+	27260156	MEWO	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.11709024886014334	[486]	[532,436,311]	-3	hSpCas9	negative selection	7535222
43115718	43115741	17	+	27260156	MEWO	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.4401528168191604	[444]	[283,320,310]	-7	hSpCas9	negative selection	7535223
43104178	43104201	17	-	27260156	MEWO	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	0.013324187021332335	[468]	[439,421,465]	0	hSpCas9	negative selection	7535224
43115763	43115786	17	-	27260156	LNCAPCLONEFGC	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-2.063550488459434	[101]	[22,25,27,11]	-9	hSpCas9	negative selection	7592189
43124016	43124039	17	-	27260156	LNCAPCLONEFGC	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.4464143127860257	[797]	[627,409,498,585]	-6	hSpCas9	negative selection	7592190
43104121	43104144	17	-	27260156	LNCAPCLONEFGC	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.0029685576086517784	[1154]	[1080,866,1207,1071]	0	hSpCas9	negative selection	7592191
43104166	43104189	17	+	27260156	LNCAPCLONEFGC	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.3279433293432282	[486]	[483,409,799,567]	5	hSpCas9	negative selection	7656473
43115718	43115741	17	+	27260156	LNCAPCLONEFGC	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.7212398338895205	[444]	[281,248,204,234]	-8	hSpCas9	negative selection	7656474
43104178	43104201	17	-	27260156	LNCAPCLONEFGC	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.21262784647180205	[468]	[402,306,396,366]	-3	hSpCas9	negative selection	7656475
43115763	43115786	17	-	27260156	PANC0327	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-4.240676801720311	[101]	[8,0,2,6]	-9	hSpCas9	negative selection	7713440
43124016	43124039	17	-	27260156	PANC0327	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.008443145751848569	[797]	[709,436,677,1061]	0	hSpCas9	negative selection	7713441
43104121	43104144	17	-	27260156	PANC0327	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.1842115656466814	[1154]	[1432,860,1264,1164]	2	hSpCas9	negative selection	7713442
43104166	43104189	17	+	27260156	PANC0327	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.4070793237997699	[486]	[278,395,307,308]	-5	hSpCas9	negative selection	7777724
43115718	43115741	17	+	27260156	PANC0327	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.06001728464294383	[444]	[506,433,307,270]	-1	hSpCas9	negative selection	7777725
43104178	43104201	17	-	27260156	PANC0327	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	0.020991103249553583	[468]	[626,432,287,357]	0	hSpCas9	negative selection	7777726
43115763	43115786	17	-	27260156	NCIH2009	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-2.3099897706889267	[101]	[19,52,10]	-9	hSpCas9	negative selection	7834691
43124016	43124039	17	-	27260156	NCIH2009	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.6352664199826121	[797]	[821,597,754]	-7	hSpCas9	negative selection	7834692
43104121	43104144	17	-	27260156	NCIH2009	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.4446567118717413	[1154]	[1389,989,1218]	-5	hSpCas9	negative selection	7834693
43104166	43104189	17	+	27260156	NCIH2009	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.14917488429047562	[486]	[636,685,519]	-2	hSpCas9	negative selection	7898975
43115718	43115741	17	+	27260156	NCIH2009	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.8709380120227599	[444]	[377,329,318]	-8	hSpCas9	negative selection	7898976
43104178	43104201	17	-	27260156	NCIH2009	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.7974532857374327	[468]	[379,376,373]	-7	hSpCas9	negative selection	7898977
43115763	43115786	17	-	27260156	NCIH1373	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-3.334582149382072	[101]	[19,3,18,0]	-9	hSpCas9	negative selection	7955942
43124016	43124039	17	-	27260156	NCIH1373	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.04682280011495621	[797]	[1209,783,1029,186]	0	hSpCas9	negative selection	7955943
43104121	43104144	17	-	27260156	NCIH1373	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.17334002494504586	[1154]	[1482,1142,1089,238]	-2	hSpCas9	negative selection	7955944
43104166	43104189	17	+	27260156	NCIH1373	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.19444296095989405	[486]	[652,492,452,84]	-2	hSpCas9	negative selection	8020226
43115718	43115741	17	+	27260156	NCIH1373	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.6194903311750019	[444]	[492,319,210,78]	-6	hSpCas9	negative selection	8020227
43104178	43104201	17	-	27260156	NCIH1373	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.7104985317560302	[468]	[206,322,402,86]	-6	hSpCas9	negative selection	8020228
43115763	43115786	17	-	27260156	PATU8902	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-5.203642932231873	[101]	[2,3,4,2]	-9	hSpCas9	negative selection	8077193
43124016	43124039	17	-	27260156	PATU8902	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.03187985733303744	[797]	[1280,1306,722,1125]	0	hSpCas9	negative selection	8077194
43104121	43104144	17	-	27260156	PATU8902	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.634255018289922	[1154]	[1160,1404,570,1131]	-6	hSpCas9	negative selection	8077195
43104166	43104189	17	+	27260156	PATU8902	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.4653766110143747	[486]	[308,779,383,522]	-4	hSpCas9	negative selection	8141477
43115718	43115741	17	+	27260156	PATU8902	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-1.2929995765940316	[444]	[203,247,392,111]	-8	hSpCas9	negative selection	8141478
43104178	43104201	17	-	27260156	PATU8902	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-1.182929221268735	[468]	[404,274,120,402]	-8	hSpCas9	negative selection	8141479
43115763	43115786	17	-	27260156	PANC1	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.9818371665113297	[101]	[19,24,21,21]	-9	hSpCas9	negative selection	8198444
43124016	43124039	17	-	27260156	PANC1	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.07802891150855173	[797]	[873,839,718,505]	1	hSpCas9	negative selection	8198445
43104121	43104144	17	-	27260156	PANC1	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.1869231368987303	[1154]	[938,921,884,753]	-3	hSpCas9	negative selection	8198446
43104166	43104189	17	+	27260156	PANC1	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.22630464528219552	[486]	[405,372,356,299]	-4	hSpCas9	negative selection	8262728
43115718	43115741	17	+	27260156	PANC1	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.8319104827313265	[444]	[206,294,250,132]	-8	hSpCas9	negative selection	8262729
43104178	43104201	17	-	27260156	PANC1	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.38417814386057303	[468]	[334,454,167,300]	-6	hSpCas9	negative selection	8262730
43115763	43115786	17	-	27260156	PANC0813	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.6043340950333058	[101]	[59,18,49,30]	-9	hSpCas9	negative selection	8319695
43124016	43124039	17	-	27260156	PANC0813	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.054239616148242575	[797]	[941,1041,1010,897]	0	hSpCas9	negative selection	8319696
43104121	43104144	17	-	27260156	PANC0813	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.03709228192464087	[1154]	[1499,1231,1316,1257]	0	hSpCas9	negative selection	8319697
43104166	43104189	17	+	27260156	PANC0813	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.18511296459790821	[486]	[394,465,646,494]	-3	hSpCas9	negative selection	8383979
43115718	43115741	17	+	27260156	PANC0813	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.6269655838855386	[444]	[421,227,298,407]	-7	hSpCas9	negative selection	8383980
43104178	43104201	17	-	27260156	PANC0813	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.39291457166629284	[468]	[532,347,336,466]	-6	hSpCas9	negative selection	8383981
43115763	43115786	17	-	27260156	RDES	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.8901820656735326	[101]	[36,25,27,33]	-9	hSpCas9	negative selection	8440946
43124016	43124039	17	-	27260156	RDES	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.008733653363273919	[797]	[655,970,968,1161]	0	hSpCas9	negative selection	8440947
43104121	43104144	17	-	27260156	RDES	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.11549106332118209	[1154]	[941,1155,1360,1528]	-2	hSpCas9	negative selection	8440948
43104166	43104189	17	+	27260156	RDES	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.042740024972806545	[486]	[455,630,578,656]	0	hSpCas9	negative selection	8505230
43115718	43115741	17	+	27260156	RDES	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.5061305937381574	[444]	[323,323,354,451]	-7	hSpCas9	negative selection	8505231
43104178	43104201	17	-	27260156	RDES	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.2259239070212256	[468]	[407,367,486,611]	-4	hSpCas9	negative selection	8505232
43115763	43115786	17	-	27260156	PC3	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.9988970008757052	[101]	[38,47,54,62]	-9	hSpCas9	negative selection	8562197
43124016	43124039	17	-	27260156	PC3	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	0.01578018720109553	[797]	[533,571,1164,1151]	0	hSpCas9	negative selection	8562198
43104121	43104144	17	-	27260156	PC3	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.2121734629782499	[1154]	[789,1228,2305,1517]	5	hSpCas9	negative selection	8562199
43104166	43104189	17	+	27260156	PC3	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.38547354260601496	[486]	[245,554,1478,724]	7	hSpCas9	negative selection	8626481
43115718	43115741	17	+	27260156	PC3	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.03197513520789383	[444]	[217,474,833,420]	0	hSpCas9	negative selection	8626482
43104178	43104201	17	-	27260156	PC3	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	0.04830519721007741	[468]	[313,396,765,602]	1	hSpCas9	negative selection	8626483
43115763	43115786	17	-	27260156	PATU8988T	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.9604797523002615	[101]	[15,23,130,25]	-8	hSpCas9	negative selection	8683448
43124016	43124039	17	-	27260156	PATU8988T	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.18057289648755503	[797]	[760,725,592,643]	-3	hSpCas9	negative selection	8683449
43104121	43104144	17	-	27260156	PATU8988T	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.3630662732686172	[1154]	[812,904,937,812]	-6	hSpCas9	negative selection	8683450
43104166	43104189	17	+	27260156	PATU8988T	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.026624042196504348	[486]	[654,524,304,362]	0	hSpCas9	negative selection	8747732
43115718	43115741	17	+	27260156	PATU8988T	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.6844096155245419	[444]	[268,355,251,195]	-8	hSpCas9	negative selection	8747733
43104178	43104201	17	-	27260156	PATU8988T	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.34169339632816453	[468]	[193,395,486,354]	-5	hSpCas9	negative selection	8747734
43115763	43115786	17	-	27260156	T47D	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.0277270214934422	[101]	[46,46,74,64]	-9	hSpCas9	negative selection	8804699
43124016	43124039	17	-	27260156	T47D	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.03502831880633461	[797]	[956,808,963,906]	-1	hSpCas9	negative selection	8804700
43104121	43104144	17	-	27260156	T47D	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.13585640479287697	[1154]	[1410,1412,1582,1510]	3	hSpCas9	negative selection	8804701
43104166	43104189	17	+	27260156	T47D	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.1686507307224685	[486]	[599,670,567,711]	3	hSpCas9	negative selection	8868983
43115718	43115741	17	+	27260156	T47D	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	0.07694337427098638	[444]	[536,529,453,672]	1	hSpCas9	negative selection	8868984
43104178	43104201	17	-	27260156	T47D	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	0.30151613342295036	[468]	[706,631,579,782]	6	hSpCas9	negative selection	8868985
43115763	43115786	17	-	27260156	SU8686	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.8664988470292512	[101]	[11,47,13,36]	-9	hSpCas9	negative selection	8925950
43124016	43124039	17	-	27260156	SU8686	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.10540497356840495	[797]	[464,723,999,796]	-2	hSpCas9	negative selection	8925951
43104121	43104144	17	-	27260156	SU8686	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.48868087900115864	[1154]	[774,634,927,977]	-7	hSpCas9	negative selection	8925952
43104166	43104189	17	+	27260156	SU8686	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.02913097806022369	[486]	[362,389,536,747]	0	hSpCas9	negative selection	8990234
43115718	43115741	17	+	27260156	SU8686	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.6995137665342578	[444]	[286,172,356,282]	-8	hSpCas9	negative selection	8990235
43104178	43104201	17	-	27260156	SU8686	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-1.1030115743639302	[468]	[234,223,204,192]	-8	hSpCas9	negative selection	8990236
43115763	43115786	17	-	27260156	SKES1	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.6048802791793291	[101]	[44,95,85,42]	-8	hSpCas9	negative selection	9047201
43124016	43124039	17	-	27260156	SKES1	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.33038550246226045	[797]	[710,638,739,465]	-6	hSpCas9	negative selection	9047202
43104121	43104144	17	-	27260156	SKES1	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.1467384908464644	[1154]	[1326,1578,1293,968]	3	hSpCas9	negative selection	9047203
43104166	43104189	17	+	27260156	SKES1	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.027889920799131787	[486]	[524,528,478,455]	0	hSpCas9	negative selection	9111485
43115718	43115741	17	+	27260156	SKES1	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.3561709554432124	[444]	[414,414,321,259]	-7	hSpCas9	negative selection	9111486
43104178	43104201	17	-	27260156	SKES1	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	0.01647377435501837	[468]	[487,481,434,484]	0	hSpCas9	negative selection	9111487
43115763	43115786	17	-	27260156	TOV112D	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.8231413389351765	[101]	[38,46,14,19]	-9	hSpCas9	negative selection	9168452
43124016	43124039	17	-	27260156	TOV112D	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.14891685912882957	[797]	[649,890,832,548]	-3	hSpCas9	negative selection	9168453
43104121	43104144	17	-	27260156	TOV112D	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.007523347964418781	[1154]	[1098,2085,840,853]	0	hSpCas9	negative selection	9168454
43104166	43104189	17	+	27260156	TOV112D	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.06813319712431183	[486]	[665,721,340,383]	1	hSpCas9	negative selection	9232736
43115718	43115741	17	+	27260156	TOV112D	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.534304311224211	[444]	[255,299,352,314]	-8	hSpCas9	negative selection	9232737
43104178	43104201	17	-	27260156	TOV112D	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	0.03723628992131938	[468]	[651,565,362,383]	0	hSpCas9	negative selection	9232738
43115763	43115786	17	-	27260156	TC71	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-0.8302146400557535	[101]	[59,42,24,122]	-9	hSpCas9	negative selection	9289703
43124016	43124039	17	-	27260156	TC71	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.16237364897604745	[797]	[670,753,767,872]	-4	hSpCas9	negative selection	9289704
43104121	43104144	17	-	27260156	TC71	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	0.1333501621211537	[1154]	[1380,1417,1375,1248]	3	hSpCas9	negative selection	9289705
43104166	43104189	17	+	27260156	TC71	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	0.04820937468426134	[486]	[501,574,520,563]	1	hSpCas9	negative selection	9353987
43115718	43115741	17	+	27260156	TC71	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.3750748745280827	[444]	[319,400,330,424]	-8	hSpCas9	negative selection	9353988
43104178	43104201	17	-	27260156	TC71	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.0890472584577632	[468]	[369,423,441,669]	-2	hSpCas9	negative selection	9353989
43115763	43115786	17	-	27260156	TC32	viability	TGCTAGTCTGGAGTTGATCAAGG	BRCA1	ENSG00000012048	-1.0956574069830167	[101]	[27,39,27,83]	-9	hSpCas9	negative selection	9410954
43124016	43124039	17	-	27260156	TC32	viability	AAATCTTAGAGTGTCCCATCTGG	BRCA1	ENSG00000012048	-0.08510779226683551	[797]	[642,503,979,796]	-1	hSpCas9	negative selection	9410955
43104121	43104144	17	-	27260156	TC32	viability	TGAACCCGAAAATCCTTCCTTGG	BRCA1	ENSG00000012048	-0.05367749578818248	[1154]	[1074,737,1216,1243]	-1	hSpCas9	negative selection	9410956
43104166	43104189	17	+	27260156	TC32	viability	GGTTTCTGTAGCCCATACTTTGG	BRCA1	ENSG00000012048	-0.10704479026882037	[486]	[400,411,498,377]	-2	hSpCas9	negative selection	9475238
43115718	43115741	17	+	27260156	TC32	viability	AAACTTACTTGCAAAATATGTGG	BRCA1	ENSG00000012048	-0.37856492297335465	[444]	[388,192,413,327]	-6	hSpCas9	negative selection	9475239
43104178	43104201	17	-	27260156	TC32	viability	AGTTTCTATCATCCAAAGTATGG	BRCA1	ENSG00000012048	-0.10057870251449183	[468]	[295,417,461,465]	-2	hSpCas9	negative selection	9475240
43074341	43074364	17	-	27869803	HPAFII	viability after 27 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.09198181200281452	[431]	[193,228,NaN]	0	hSpCas9	negative selection	9561018
43076560	43076583	17	-	27869803	HPAFII	viability after 27 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	-0.33545395145809054	[131]	[42,64,NaN]	-3	hSpCas9	negative selection	9561019
43082470	43082493	17	+	27869803	HPAFII	viability after 27 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-1.0695079502043932	[179]	[49,40,NaN]	-6	hSpCas9	negative selection	9561020
43092301	43092324	17	-	27869803	HPAFII	viability after 27 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.034208387381712946	[839]	[373,478,NaN]	0	hSpCas9	negative selection	9561021
43099851	43099874	17	+	27869803	HPAFII	viability after 27 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.68782472032131	[282]	[69,110,NaN]	-5	hSpCas9	negative selection	9561022
43124001	43124024	17	+	27869803	HPAFII	viability after 27 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.5361770896643838	[166]	[2,52,NaN]	-7	hSpCas9	negative selection	9561023
43074341	43074364	17	-	27869803	HPAFII	viability after 15 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	0.082973880910852	[431]	[685,370,NaN]	1	hSpCas9	negative selection	9643467
43076560	43076583	17	-	27869803	HPAFII	viability after 15 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.0423113654391688	[131]	[179,124,NaN]	0	hSpCas9	negative selection	9643468
43082470	43082493	17	+	27869803	HPAFII	viability after 15 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.3165490390938734	[179]	[216,116,NaN]	-4	hSpCas9	negative selection	9643469
43092301	43092324	17	-	27869803	HPAFII	viability after 15 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.3217823801304469	[839]	[807,668,NaN]	-4	hSpCas9	negative selection	9643470
43099851	43099874	17	+	27869803	HPAFII	viability after 15 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.012406996006259274	[282]	[414,230,NaN]	0	hSpCas9	negative selection	9643471
43124001	43124024	17	+	27869803	HPAFII	viability after 15 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.2648879393600028	[166]	[115,48,NaN]	-8	hSpCas9	negative selection	9643472
43074341	43074364	17	-	27869803	ASPC1	viability after 36 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-1.182770008534565	[1082]	[182,157,159]	-8	hSpCas9	negative selection	9725916
43076560	43076583	17	-	27869803	ASPC1	viability after 36 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	-0.49872042625507906	[258]	[88,103,13]	-5	hSpCas9	negative selection	9725917
43082470	43082493	17	+	27869803	ASPC1	viability after 36 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-1.167329779768096	[378]	[37,78,56]	-8	hSpCas9	negative selection	9725918
43092301	43092324	17	-	27869803	ASPC1	viability after 36 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.9977016569133309	[2349]	[618,394,272]	-7	hSpCas9	negative selection	9725919
43099851	43099874	17	+	27869803	ASPC1	viability after 36 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.09289245707176913	[732]	[397,203,154]	-1	hSpCas9	negative selection	9725920
43124001	43124024	17	+	27869803	ASPC1	viability after 36 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	0.37252507675746616	[430]	[157,202,211]	4	hSpCas9	negative selection	9725921
43074341	43074364	17	-	27869803	PATU8988S	viability after 35 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-1.7756586082149792	[1053]	[114,132,NaN]	-8	hSpCas9	negative selection	9808365
43076560	43076583	17	-	27869803	PATU8988S	viability after 35 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.003918430603177203	[228]	[83,100,NaN]	0	hSpCas9	negative selection	9808366
43082470	43082493	17	+	27869803	PATU8988S	viability after 35 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.5118380430746692	[371]	[137,71,NaN]	-5	hSpCas9	negative selection	9808367
43092301	43092324	17	-	27869803	PATU8988S	viability after 35 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.6326261522483954	[1928]	[546,454,NaN]	-6	hSpCas9	negative selection	9808368
43099851	43099874	17	+	27869803	PATU8988S	viability after 35 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.5555522975086311	[778]	[199,226,NaN]	-5	hSpCas9	negative selection	9808369
43124001	43124024	17	+	27869803	PATU8988S	viability after 35 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-2.9722233707725567	[359]	[7,28,NaN]	-9	hSpCas9	negative selection	9808370
43074341	43074364	17	-	27869803	PATU8988S	viability after 31 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-1.4502547426259815	[1053]	[166,136,NaN]	-8	hSpCas9	negative selection	9890814
43076560	43076583	17	-	27869803	PATU8988S	viability after 31 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	0.6506763314022816	[228]	[101,195,NaN]	7	hSpCas9	negative selection	9890815
43082470	43082493	17	+	27869803	PATU8988S	viability after 31 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.790350287860361	[371]	[116,45,NaN]	-7	hSpCas9	negative selection	9890816
43092301	43092324	17	-	27869803	PATU8988S	viability after 31 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.6156006158134897	[1928]	[545,445,NaN]	-6	hSpCas9	negative selection	9890817
43099851	43099874	17	+	27869803	PATU8988S	viability after 31 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.543289383730683	[778]	[162,276,NaN]	-5	hSpCas9	negative selection	9890818
43124001	43124024	17	+	27869803	PATU8988S	viability after 31 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-2.840679781643969	[359]	[12,28,NaN]	-9	hSpCas9	negative selection	9890819
43074341	43074364	17	-	27869803	HPAFII	viability after 35 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.20294334083584564	[431]	[189,189,NaN]	-1	hSpCas9	negative selection	9973263
43076560	43076583	17	-	27869803	HPAFII	viability after 35 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	-1.375528252530571	[131]	[5,47,NaN]	-6	hSpCas9	negative selection	9973264
43082470	43082493	17	+	27869803	HPAFII	viability after 35 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-0.9902992157954649	[179]	[19,74,NaN]	-5	hSpCas9	negative selection	9973265
43092301	43092324	17	-	27869803	HPAFII	viability after 35 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	0.2271921408807862	[839]	[398,608,NaN]	1	hSpCas9	negative selection	9973266
43099851	43099874	17	+	27869803	HPAFII	viability after 35 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.36384497109333347	[282]	[68,158,NaN]	-2	hSpCas9	negative selection	9973267
43124001	43124024	17	+	27869803	HPAFII	viability after 35 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.5614411351869464	[166]	[22,34,NaN]	-7	hSpCas9	negative selection	9973268
43074341	43074364	17	-	27869803	HPAFII	viability after 31 days	CGGAAACATCTTACTTGCCAAGG	BRCA1	ENSG00000012048	-0.25892421496847795	[431]	[193,211,NaN]	-2	hSpCas9	negative selection	10055712
43076560	43076583	17	-	27869803	HPAFII	viability after 31 days	CCTATAAGCCAGAATCCAGAAGG	BRCA1	ENSG00000012048	-0.8921896312186992	[131]	[37,41,NaN]	-5	hSpCas9	negative selection	10055713
43082470	43082493	17	+	27869803	HPAFII	viability after 31 days	AAGGGTAGCTGTTAGAAGGCTGG	BRCA1	ENSG00000012048	-1.6779342593205895	[179]	[21,41,NaN]	-7	hSpCas9	negative selection	10055714
43092301	43092324	17	-	27869803	HPAFII	viability after 31 days	GCAGAACTAGGTAGAAACAGAGG	BRCA1	ENSG00000012048	-0.10556975025775373	[839]	[396,482,NaN]	0	hSpCas9	negative selection	10055715
43099851	43099874	17	+	27869803	HPAFII	viability after 31 days	AGAGAGTTGGACACTGAGACTGG	BRCA1	ENSG00000012048	-0.3960051772889654	[282]	[113,127,NaN]	-3	hSpCas9	negative selection	10055716
43124001	43124024	17	+	27869803	HPAFII	viability after 31 days	TCTTGTGCTGACTTACCAGATGG	BRCA1	ENSG00000012048	-1.7429781707411904	[166]	[27,27,NaN]	-7	hSpCas9	negative selection	10055717
43099812	43099835	17	-	28162770	P31FUJ	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.5677864521271871	[332]	[263]	-5	hSpCas9	negative selection	10119000
43071102	43071125	17	+	28162770	P31FUJ	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	0.11526830527521459	[699]	[890]	1	hSpCas9	negative selection	10119001
43082527	43082550	17	-	28162770	P31FUJ	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	0.273550461610411	[175]	[249]	3	hSpCas9	negative selection	10119002
43070940	43070963	17	+	28162770	P31FUJ	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-2.4344360655840287	[206]	[44]	-8	hSpCas9	negative selection	10119003
43057060	43057083	17	-	28162770	P31FUJ	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.163539541977265	[121]	[63]	-7	hSpCas9	negative selection	10119004
43082496	43082519	17	-	28162770	P31FUJ	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.1015576711361263	[251]	[137]	-6	hSpCas9	negative selection	10119005
43057086	43057109	17	-	28162770	P31FUJ	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-1.6246029951228411	[348]	[132]	-7	hSpCas9	negative selection	10119006
43047676	43047699	17	+	28162770	P31FUJ	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-0.7218402851369992	[79]	[56]	-5	hSpCas9	negative selection	10119007
43047651	43047674	17	-	28162770	P31FUJ	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-1.57675660563174	[395]	[155]	-7	hSpCas9	negative selection	10119008
43071157	43071180	17	+	28162770	P31FUJ	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	0.5501986330193922	[622]	[1071]	6	hSpCas9	negative selection	10119009
43099812	43099835	17	-	28162770	TF1	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10288366
43071102	43071125	17	+	28162770	TF1	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	NaN	[NaN]	[485]	1	hSpCas9	negative selection	10288367
43082527	43082550	17	-	28162770	TF1	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	NaN	[NaN]	[54]	1	hSpCas9	negative selection	10288368
43070940	43070963	17	+	28162770	TF1	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10288369
43057060	43057083	17	-	28162770	TF1	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10288370
43082496	43082519	17	-	28162770	TF1	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10288371
43057086	43057109	17	-	28162770	TF1	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	NaN	[NaN]	[144]	1	hSpCas9	negative selection	10288372
43047676	43047699	17	+	28162770	TF1	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	NaN	[NaN]	[15]	1	hSpCas9	negative selection	10288373
43047651	43047674	17	-	28162770	TF1	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10288374
43071157	43071180	17	+	28162770	TF1	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	NaN	[NaN]	[414]	1	hSpCas9	negative selection	10288375
43099812	43099835	17	-	28162770	SKM1	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.27837999268174873	[117]	[171]	-2	hSpCas9	negative selection	10457732
43071102	43071125	17	+	28162770	SKM1	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	0.5042915894267586	[131]	[330]	5	hSpCas9	negative selection	10457733
43082527	43082550	17	-	28162770	SKM1	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-2.5513541080783364	[62]	[18]	-9	hSpCas9	negative selection	10457734
43070940	43070963	17	+	28162770	SKM1	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-1.291486981323226	[53]	[38]	-7	hSpCas9	negative selection	10457735
43057060	43057083	17	-	28162770	SKM1	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.4740783946016984	[32]	[20]	-7	hSpCas9	negative selection	10457736
43082496	43082519	17	-	28162770	SKM1	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.274513902719512	[77]	[56]	-7	hSpCas9	negative selection	10457737
43057086	43057109	17	-	28162770	SKM1	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-0.28390580233882357	[72]	[105]	-2	hSpCas9	negative selection	10457738
43047676	43047699	17	+	28162770	SKM1	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-0.8220016980220057	[9]	[9]	-6	hSpCas9	negative selection	10457739
43047651	43047674	17	-	28162770	SKM1	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-1.2241001415933512	[73]	[55]	-7	hSpCas9	negative selection	10457740
43071157	43071180	17	+	28162770	SKM1	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.0667352871128557	[140]	[237]	0	hSpCas9	negative selection	10457741
43099812	43099835	17	-	28162770	SKM1	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.27837999268174873	[117]	[171]	-2	hSpCas9	negative selection	10627098
43071102	43071125	17	+	28162770	SKM1	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	0.5042915894267586	[131]	[330]	5	hSpCas9	negative selection	10627099
43082527	43082550	17	-	28162770	SKM1	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-2.5513541080783364	[62]	[18]	-9	hSpCas9	negative selection	10627100
43070940	43070963	17	+	28162770	SKM1	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-1.291486981323226	[53]	[38]	-7	hSpCas9	negative selection	10627101
43057060	43057083	17	-	28162770	SKM1	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.4740783946016984	[32]	[20]	-7	hSpCas9	negative selection	10627102
43082496	43082519	17	-	28162770	SKM1	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.274513902719512	[77]	[56]	-7	hSpCas9	negative selection	10627103
43057086	43057109	17	-	28162770	SKM1	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-0.28390580233882357	[72]	[105]	-2	hSpCas9	negative selection	10627104
43047676	43047699	17	+	28162770	SKM1	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-0.8220016980220057	[9]	[9]	-6	hSpCas9	negative selection	10627105
43047651	43047674	17	-	28162770	SKM1	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-1.2241001415933512	[73]	[55]	-7	hSpCas9	negative selection	10627106
43071157	43071180	17	+	28162770	SKM1	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.0667352871128557	[140]	[237]	0	hSpCas9	negative selection	10627107
43099812	43099835	17	-	28162770	PL21	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	0.3076927556441237	[322]	[173]	2	hSpCas9	negative selection	10796464
43071102	43071125	17	+	28162770	PL21	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	1.0765902622541477	[462]	[424]	8	hSpCas9	negative selection	10796465
43082527	43082550	17	-	28162770	PL21	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	1.588269240304647	[229]	[300]	9	hSpCas9	negative selection	10796466
43070940	43070963	17	+	28162770	PL21	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-0.5719084388323313	[221]	[64]	-4	hSpCas9	negative selection	10796467
43057060	43057083	17	-	28162770	PL21	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.5340488950063123	[172]	[25]	-7	hSpCas9	negative selection	10796468
43082496	43082519	17	-	28162770	PL21	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	0.8614881620108312	[281]	[222]	7	hSpCas9	negative selection	10796469
43057086	43057109	17	-	28162770	PL21	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-1.305559607707183	[300]	[52]	-7	hSpCas9	negative selection	10796470
43047676	43047699	17	+	28162770	PL21	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-3.280987075247297	[66]	[2]	-9	hSpCas9	negative selection	10796471
43047651	43047674	17	-	28162770	PL21	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	0.08842922699230332	[254]	[117]	0	hSpCas9	negative selection	10796472
43071157	43071180	17	+	28162770	PL21	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	0.3636383467721995	[449]	[251]	3	hSpCas9	negative selection	10796473
43099812	43099835	17	-	28162770	P31FUJ	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.5677864521271871	[332]	[263]	-5	hSpCas9	negative selection	10965830
43071102	43071125	17	+	28162770	P31FUJ	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	0.11526830527521459	[699]	[890]	1	hSpCas9	negative selection	10965831
43082527	43082550	17	-	28162770	P31FUJ	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	0.273550461610411	[175]	[249]	3	hSpCas9	negative selection	10965832
43070940	43070963	17	+	28162770	P31FUJ	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-2.4344360655840287	[206]	[44]	-8	hSpCas9	negative selection	10965833
43057060	43057083	17	-	28162770	P31FUJ	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.163539541977265	[121]	[63]	-7	hSpCas9	negative selection	10965834
43082496	43082519	17	-	28162770	P31FUJ	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.1015576711361263	[251]	[137]	-6	hSpCas9	negative selection	10965835
43057086	43057109	17	-	28162770	P31FUJ	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-1.6246029951228411	[348]	[132]	-7	hSpCas9	negative selection	10965836
43047676	43047699	17	+	28162770	P31FUJ	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-0.7218402851369992	[79]	[56]	-5	hSpCas9	negative selection	10965837
43047651	43047674	17	-	28162770	P31FUJ	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-1.57675660563174	[395]	[155]	-7	hSpCas9	negative selection	10965838
43071157	43071180	17	+	28162770	P31FUJ	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	0.5501986330193922	[622]	[1071]	6	hSpCas9	negative selection	10965839
43099812	43099835	17	-	28162770	OCIAML5	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.736589353444061	[179]	[194]	-5	hSpCas9	negative selection	11135196
43071102	43071125	17	+	28162770	OCIAML5	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	-0.5667630011891704	[374]	[456]	-4	hSpCas9	negative selection	11135197
43082527	43082550	17	-	28162770	OCIAML5	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-1.9589817747805092	[223]	[103]	-8	hSpCas9	negative selection	11135198
43070940	43070963	17	+	28162770	OCIAML5	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-2.157875000388082	[88]	[35]	-8	hSpCas9	negative selection	11135199
43057060	43057083	17	-	28162770	OCIAML5	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-0.34239219744707805	[58]	[83]	-2	hSpCas9	negative selection	11135200
43082496	43082519	17	-	28162770	OCIAML5	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.3694657877725187	[145]	[101]	-7	hSpCas9	negative selection	11135201
43057086	43057109	17	-	28162770	OCIAML5	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-1.2977542829830253	[221]	[162]	-6	hSpCas9	negative selection	11135202
43047676	43047699	17	+	28162770	OCIAML5	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-1.7879362334442812	[43]	[22]	-7	hSpCas9	negative selection	11135203
43047651	43047674	17	-	28162770	OCIAML5	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-1.9547522348385609	[130]	[60]	-8	hSpCas9	negative selection	11135204
43071157	43071180	17	+	28162770	OCIAML5	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.5680216717376649	[408]	[497]	-4	hSpCas9	negative selection	11135205
43099812	43099835	17	-	28162770	EOL1	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.3742143387377853	[555]	[225]	-3	hSpCas9	negative selection	11304562
43071102	43071125	17	+	28162770	EOL1	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	-0.18434090096804223	[618]	[286]	-1	hSpCas9	negative selection	11304563
43082527	43082550	17	-	28162770	EOL1	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	1.2088233249784985	[426]	[519]	8	hSpCas9	negative selection	11304564
43070940	43070963	17	+	28162770	EOL1	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	1.2150401729110751	[398]	[487]	8	hSpCas9	negative selection	11304565
43057060	43057083	17	-	28162770	EOL1	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	0.37546230717797496	[277]	[189]	3	hSpCas9	negative selection	11304566
43082496	43082519	17	-	28162770	EOL1	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-0.6109460528863218	[515]	[177]	-4	hSpCas9	negative selection	11304567
43057086	43057109	17	-	28162770	EOL1	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-0.9006184266035303	[325]	[91]	-6	hSpCas9	negative selection	11304568
43047676	43047699	17	+	28162770	EOL1	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-2.9629774991710525	[73]	[4]	-9	hSpCas9	negative selection	11304569
43047651	43047674	17	-	28162770	EOL1	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-2.5188981428940633	[358]	[32]	-8	hSpCas9	negative selection	11304570
43071157	43071180	17	+	28162770	EOL1	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.14792186676191066	[693]	[329]	-1	hSpCas9	negative selection	11304571
43099812	43099835	17	-	28162770	MOLM13	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.3453795799348248	[549]	[312]	-2	hSpCas9	negative selection	11473928
43071102	43071125	17	+	28162770	MOLM13	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	-1.3201915283484817	[631]	[182]	-6	hSpCas9	negative selection	11473929
43082527	43082550	17	-	28162770	MOLM13	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-0.6635364289897883	[378]	[172]	-4	hSpCas9	negative selection	11473930
43070940	43070963	17	+	28162770	MOLM13	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-3.966097220535255	[280]	[12]	-9	hSpCas9	negative selection	11473931
43057060	43057083	17	-	28162770	MOLM13	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.5549505948135325	[190]	[46]	-6	hSpCas9	negative selection	11473932
43082496	43082519	17	-	28162770	MOLM13	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.1170731191765775	[356]	[118]	-5	hSpCas9	negative selection	11473933
43057086	43057109	17	-	28162770	MOLM13	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-1.7637363195699063	[417]	[88]	-7	hSpCas9	negative selection	11473934
43047676	43047699	17	+	28162770	MOLM13	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-2.2239883230930895	[83]	[12]	-7	hSpCas9	negative selection	11473935
43047651	43047674	17	-	28162770	MOLM13	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-2.431286248935934	[372]	[49]	-8	hSpCas9	negative selection	11473936
43071157	43071180	17	+	28162770	MOLM13	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.7167398126753685	[640]	[281]	-4	hSpCas9	negative selection	11473937
43099812	43099835	17	-	28162770	HEL	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	0.7163958737256658	[419]	[441]	6	hSpCas9	negative selection	11643294
43071102	43071125	17	+	28162770	HEL	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	-0.07126561372253826	[560]	[341]	0	hSpCas9	negative selection	11643295
43082527	43082550	17	-	28162770	HEL	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	0.25794094589919603	[298]	[228]	2	hSpCas9	negative selection	11643296
43070940	43070963	17	+	28162770	HEL	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-1.5082030660743828	[301]	[67]	-7	hSpCas9	negative selection	11643297
43057060	43057083	17	-	28162770	HEL	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.340773045211074	[173]	[43]	-6	hSpCas9	negative selection	11643298
43082496	43082519	17	-	28162770	HEL	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-0.9873115582493373	[389]	[125]	-6	hSpCas9	negative selection	11643299
43057086	43057109	17	-	28162770	HEL	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-1.509264261444693	[359]	[80]	-7	hSpCas9	negative selection	11643300
43047676	43047699	17	+	28162770	HEL	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-3.5271861694419555	[71]	[3]	-9	hSpCas9	negative selection	11643301
43047651	43047674	17	-	28162770	HEL	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-3.146582167226986	[317]	[22]	-9	hSpCas9	negative selection	11643302
43071157	43071180	17	+	28162770	HEL	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.8281992120200719	[534]	[192]	-5	hSpCas9	negative selection	11643303
43099812	43099835	17	-	28162770	MV411	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.8994038375464959	[278]	[125]	-6	hSpCas9	negative selection	11812660
43071102	43071125	17	+	28162770	MV411	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	-0.4312603882042503	[460]	[287]	-3	hSpCas9	negative selection	11812661
43082527	43082550	17	-	28162770	MV411	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-0.5658617350240854	[303]	[172]	-4	hSpCas9	negative selection	11812662
43070940	43070963	17	+	28162770	MV411	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-2.307151300894862	[187]	[31]	-8	hSpCas9	negative selection	11812663
43057060	43057083	17	-	28162770	MV411	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-0.4639363294806902	[148]	[90]	-3	hSpCas9	negative selection	11812664
43082496	43082519	17	-	28162770	MV411	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-0.8661250080404245	[250]	[115]	-5	hSpCas9	negative selection	11812665
43057086	43057109	17	-	28162770	MV411	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-1.024235773324891	[267]	[110]	-6	hSpCas9	negative selection	11812666
43047676	43047699	17	+	28162770	MV411	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-5.729842372717141	[62]	[0]	-9	hSpCas9	negative selection	11812667
43047651	43047674	17	-	28162770	MV411	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-1.1061994038319252	[183]	[71]	-6	hSpCas9	negative selection	11812668
43071157	43071180	17	+	28162770	MV411	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.7310063058507772	[464]	[235]	-5	hSpCas9	negative selection	11812669
43099812	43099835	17	-	28162770	MONOMAC1	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.4475803087101508	[137]	[115]	-4	hSpCas9	negative selection	11982026
43071102	43071125	17	+	28162770	MONOMAC1	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	0.19290967125645953	[289]	[379]	2	hSpCas9	negative selection	11982027
43082527	43082550	17	-	28162770	MONOMAC1	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-0.8825262237346744	[155]	[96]	-6	hSpCas9	negative selection	11982028
43070940	43070963	17	+	28162770	MONOMAC1	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-0.7693993110010763	[170]	[114]	-6	hSpCas9	negative selection	11982029
43057060	43057083	17	-	28162770	MONOMAC1	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	0.3561169154309264	[106]	[156]	3	hSpCas9	negative selection	11982030
43082496	43082519	17	-	28162770	MONOMAC1	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-0.04833511670475488	[174]	[193]	0	hSpCas9	negative selection	11982031
43057086	43057109	17	-	28162770	MONOMAC1	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-0.8491135436392467	[153]	[97]	-6	hSpCas9	negative selection	11982032
43047676	43047699	17	+	28162770	MONOMAC1	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-0.8626178079889943	[45]	[28]	-6	hSpCas9	negative selection	11982033
43047651	43047674	17	-	28162770	MONOMAC1	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-0.44145557472600044	[153]	[129]	-4	hSpCas9	negative selection	11982034
43071157	43071180	17	+	28162770	MONOMAC1	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	0.08580603985442059	[216]	[263]	0	hSpCas9	negative selection	11982035
43099812	43099835	17	-	28162770	OCIAML2	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.5210033477572805	[50]	[196]	-4	hSpCas9	negative selection	12151392
43071102	43071125	17	+	28162770	OCIAML2	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	-0.12241043253587125	[86]	[442]	-1	hSpCas9	negative selection	12151393
43082527	43082550	17	-	28162770	OCIAML2	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-0.3343641351510801	[52]	[232]	-3	hSpCas9	negative selection	12151394
43070940	43070963	17	+	28162770	OCIAML2	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-1.992582528437517	[27]	[38]	-8	hSpCas9	negative selection	12151395
43057060	43057083	17	-	28162770	OCIAML2	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	-1.183053235145576	[33]	[82]	-6	hSpCas9	negative selection	12151396
43082496	43082519	17	-	28162770	OCIAML2	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-2.2928427060268786	[60]	[68]	-8	hSpCas9	negative selection	12151397
43057086	43057109	17	-	28162770	OCIAML2	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-2.1837486774539996	[49]	[60]	-8	hSpCas9	negative selection	12151398
43047676	43047699	17	+	28162770	OCIAML2	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-3.9300614438794588	[10]	[3]	-9	hSpCas9	negative selection	12151399
43047651	43047674	17	-	28162770	OCIAML2	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-1.6158277407820967	[46]	[84]	-7	hSpCas9	negative selection	12151400
43071157	43071180	17	+	28162770	OCIAML2	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.05446566050903301	[79]	[426]	0	hSpCas9	negative selection	12151401
43099812	43099835	17	-	28162770	OCIAML3	viability	GAACTCTGAGGACAAAGCAGCGG	BRCA1	ENSG00000012048	-0.7166901600989919	[91]	[168]	-5	hSpCas9	negative selection	12320758
43071102	43071125	17	+	28162770	OCIAML3	viability	TTGGGGAACTTTCAATGCAGAGG	BRCA1	ENSG00000012048	0.9103364001887086	[137]	[782]	7	hSpCas9	negative selection	12320759
43082527	43082550	17	-	28162770	OCIAML3	viability	GATAAAGCTCCAGCAGGAAATGG	BRCA1	ENSG00000012048	-0.5539302009488279	[70]	[145]	-4	hSpCas9	negative selection	12320760
43070940	43070963	17	+	28162770	OCIAML3	viability	GGTCAGGCCAGACACCACCATGG	BRCA1	ENSG00000012048	-2.0414666172953844	[59]	[43]	-8	hSpCas9	negative selection	12320761
43057060	43057083	17	-	28162770	OCIAML3	viability	AAAGCGAGCAAGAGAATCCCAGG	BRCA1	ENSG00000012048	1.5460821315773863	[37]	[334]	9	hSpCas9	negative selection	12320762
43082496	43082519	17	-	28162770	OCIAML3	viability	GAAGCTGTGTTAGAACAGCATGG	BRCA1	ENSG00000012048	-1.143346231314598	[89]	[122]	-7	hSpCas9	negative selection	12320763
43057086	43057109	17	-	28162770	OCIAML3	viability	GTCAATGGAAGAAACCACCAAGG	BRCA1	ENSG00000012048	-2.3507364893117995	[97]	[57]	-9	hSpCas9	negative selection	12320764
43047676	43047699	17	+	28162770	OCIAML3	viability	GCTGCACAACCACAATTGGGTGG	BRCA1	ENSG00000012048	-2.3309732344903686	[14]	[8]	-9	hSpCas9	negative selection	12320765
43047651	43047674	17	-	28162770	OCIAML3	viability	GATGCCTGGACAGAGGACAATGG	BRCA1	ENSG00000012048	-1.594007640324163	[74]	[74]	-8	hSpCas9	negative selection	12320766
43071157	43071180	17	+	28162770	OCIAML3	viability	TCTGGGGCTCTGTCTTCAGAAGG	BRCA1	ENSG00000012048	-0.6083154770080464	[151]	[300]	-5	hSpCas9	negative selection	12320767