Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:680
• Symbol:BRS3
• Description:bombesin receptor subtype 3

DataSource: http://genomecrispr.dkfz.de/#!/results/BRS3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
136488374	136488397	X	-	26472758	Jiyoye	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	-0.028923733300800142	[114]	[84]	0	hSpCas9	negative selection	16261
136488492	136488515	X	-	26472758	Jiyoye	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	5.799492804284633	[0]	[41]	9	hSpCas9	negative selection	16262
136488427	136488450	X	+	26472758	Jiyoye	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.460946637946854	[78]	[81]	3	hSpCas9	negative selection	16263
136488402	136488425	X	+	26472758	Jiyoye	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	0.05667813442174005	[101]	[79]	0	hSpCas9	negative selection	16264
136488130	136488153	X	-	26472758	Jiyoye	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	1.095231375191133	[179]	[289]	7	hSpCas9	negative selection	16265
136488448	136488471	X	+	26472758	Jiyoye	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.5998204594482693	[69]	[79]	4	hSpCas9	negative selection	16266
136490411	136490434	X	-	26472758	Jiyoye	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.010996909478345307	[303]	[230]	0	hSpCas9	negative selection	16267
136490168	136490191	X	-	26472758	Jiyoye	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	-0.0708719152987709	[194]	[139]	0	hSpCas9	negative selection	16268
136490182	136490205	X	+	26472758	Jiyoye	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	-0.22245616854901096	[81]	[52]	-1	hSpCas9	negative selection	16269
136488206	136488229	X	+	26472758	Jiyoye	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	-1.2075344626093347	[146]	[47]	-7	hSpCas9	negative selection	16270
136488374	136488397	X	-	26472758	KBM7	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	0.9079543707679631	[271,135]	[264,93]	8	hSpCas9	negative selection	207379
136488492	136488515	X	-	26472758	KBM7	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.5052084308840671	[185,283]	[81,77]	-4	hSpCas9	negative selection	207380
136488427	136488450	X	+	26472758	KBM7	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.1719749168140267	[355,395]	[196,204]	1	hSpCas9	negative selection	207381
136488402	136488425	X	+	26472758	KBM7	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	0.6078885911886955	[496,362]	[479,147]	6	hSpCas9	negative selection	207382
136488130	136488153	X	-	26472758	KBM7	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.571038620091108	[1004,788]	[774,484]	6	hSpCas9	negative selection	207383
136488448	136488471	X	+	26472758	KBM7	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.10580232561164021	[372,301]	[230,114]	1	hSpCas9	negative selection	207384
136490411	136490434	X	-	26472758	KBM7	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.7047931536603627	[1077,1141]	[1247,507]	7	hSpCas9	negative selection	207385
136490168	136490191	X	-	26472758	KBM7	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.13950004938566174	[993,1223]	[634,536]	1	hSpCas9	negative selection	207386
136490182	136490205	X	+	26472758	KBM7	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	-0.3292598231506272	[183,232]	[119,42]	-3	hSpCas9	negative selection	207387
136488206	136488229	X	+	26472758	KBM7	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	0.6153651512035494	[278,250]	[194,186]	6	hSpCas9	negative selection	207388
136488374	136488397	X	-	26472758	Raji	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	0.5928103625438412	[119]	[41]	5	hSpCas9	negative selection	398497
136488492	136488515	X	-	26472758	Raji	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	1.738996129393577	[70]	[54]	9	hSpCas9	negative selection	398498
136488427	136488450	X	+	26472758	Raji	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.5135428833059904	[162]	[53]	5	hSpCas9	negative selection	398499
136488402	136488425	X	+	26472758	Raji	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	0.4817790501550974	[215]	[69]	4	hSpCas9	negative selection	398500
136488130	136488153	X	-	26472758	Raji	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.3568349689344683	[497]	[147]	3	hSpCas9	negative selection	398501
136488448	136488471	X	+	26472758	Raji	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.420883008190381	[205]	[63]	4	hSpCas9	negative selection	398502
136490411	136490434	X	-	26472758	Raji	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.5449636033035317	[634]	[214]	5	hSpCas9	negative selection	398503
136490168	136490191	X	-	26472758	Raji	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.5490889851145233	[535]	[181]	5	hSpCas9	negative selection	398504
136490182	136490205	X	+	26472758	Raji	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	-0.7339187186073424	[128]	[17]	-5	hSpCas9	negative selection	398505
136488206	136488229	X	+	26472758	Raji	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	0.8323764878737296	[120]	[49]	7	hSpCas9	negative selection	398506
136488374	136488397	X	-	26472758	K562	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	0.19117670638946738	[137]	[132]	1	hSpCas9	negative selection	589615
136488492	136488515	X	-	26472758	K562	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	2.1237372452439836	[80]	[297]	9	hSpCas9	negative selection	589616
136488427	136488450	X	+	26472758	K562	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	-0.23611207091042333	[352]	[252]	-2	hSpCas9	negative selection	589617
136488402	136488425	X	+	26472758	K562	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	0.6603976266791112	[382]	[510]	5	hSpCas9	negative selection	589618
136488130	136488153	X	-	26472758	K562	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.4585435330192942	[849]	[985]	3	hSpCas9	negative selection	589619
136488448	136488471	X	+	26472758	K562	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	1.1194758606878912	[222]	[408]	8	hSpCas9	negative selection	589620
136490411	136490434	X	-	26472758	K562	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.6638082514849977	[992]	[1327]	5	hSpCas9	negative selection	589621
136490168	136490191	X	-	26472758	K562	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.6817512666356436	[914]	[1238]	5	hSpCas9	negative selection	589622
136490182	136490205	X	+	26472758	K562	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	1.6246908087846141	[188]	[491]	9	hSpCas9	negative selection	589623
136488206	136488229	X	+	26472758	K562	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	0.9932864108889448	[168]	[283]	8	hSpCas9	negative selection	589624
136488492	136488515	X	-	26627737	DLD1	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	1.4586470704698606	[261]	[173,419,107]	9	hSpCas9	negative selection	844592
136490152	136490175	X	-	26627737	DLD1	viability	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.3209653525616614	[612]	[315,318,106]	3	hSpCas9	negative selection	844593
136490463	136490486	X	+	26627737	DLD1	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.20470129122523395	[855]	[333,409,201]	2	hSpCas9	negative selection	844594
136492153	136492176	X	-	26627737	DLD1	viability	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.35100174559063224	[993]	[312,507,375]	3	hSpCas9	negative selection	844595
136492249	136492272	X	+	26627737	DLD1	viability	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.3426927822494463	[1193]	[456,150,271]	-4	hSpCas9	negative selection	844596
136492267	136492290	X	-	26627737	DLD1	viability	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.6029359174121387	[473]	[296,249,141]	6	hSpCas9	negative selection	844597
136488492	136488515	X	-	26627737	GBM cells	viability after 5 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.07519055576911568	[276]	[181,130]	1	hSpCas9	negative selection	926907
136490152	136490175	X	-	26627737	GBM cells	viability after 5 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.218125881664465	[318]	[175,221]	3	hSpCas9	negative selection	926908
136490463	136490486	X	+	26627737	GBM cells	viability after 5 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.1438732772648772	[588]	[346,350]	2	hSpCas9	negative selection	926909
136492153	136492176	X	-	26627737	GBM cells	viability after 5 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.15161096795020845	[746]	[415,473]	2	hSpCas9	negative selection	926910
136492249	136492272	X	+	26627737	GBM cells	viability after 5 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.14506382217491653	[432]	[227,191]	-2	hSpCas9	negative selection	926911
136492267	136492290	X	-	26627737	GBM cells	viability after 5 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.4838763756068419	[213]	[170,149]	7	hSpCas9	negative selection	926912
136488492	136488515	X	-	26627737	GBM cells	viability after 13 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.02161238256010098	[276]	[200,104]	0	hSpCas9	negative selection	1009222
136490152	136490175	X	-	26627737	GBM cells	viability after 13 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.25479121899634893	[318]	[275,149]	3	hSpCas9	negative selection	1009223
136490463	136490486	X	+	26627737	GBM cells	viability after 13 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.7229663626803846	[588]	[607,461]	8	hSpCas9	negative selection	1009224
136492153	136492176	X	-	26627737	GBM cells	viability after 13 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.21478371235178195	[746]	[519,429]	2	hSpCas9	negative selection	1009225
136492249	136492272	X	+	26627737	GBM cells	viability after 13 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	0.15068810318152936	[432]	[353,184]	2	hSpCas9	negative selection	1009226
136492267	136492290	X	-	26627737	GBM cells	viability after 13 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.9606742778733746	[213]	[177,264]	9	hSpCas9	negative selection	1009227
136488492	136488515	X	-	26627737	GBM cells	viability after 21 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.20639125970865382	[276]	[193,154]	2	hSpCas9	negative selection	1091537
136490152	136490175	X	-	26627737	GBM cells	viability after 21 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.6047231557903705	[318]	[285,242]	6	hSpCas9	negative selection	1091538
136490463	136490486	X	+	26627737	GBM cells	viability after 21 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.6706072751614158	[588]	[512,505]	6	hSpCas9	negative selection	1091539
136492153	136492176	X	-	26627737	GBM cells	viability after 21 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.19206285560601555	[746]	[372,338]	-2	hSpCas9	negative selection	1091540
136492249	136492272	X	+	26627737	GBM cells	viability after 21 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.34280095587570847	[432]	[173,195]	-3	hSpCas9	negative selection	1091541
136492267	136492290	X	-	26627737	GBM cells	viability after 21 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.884421965057492	[213]	[199,227]	8	hSpCas9	negative selection	1091542
136488492	136488515	X	-	26627737	RPE1	viability after 9 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.9032360332525804	[305]	[76,310]	6	hSpCas9	negative selection	1173852
136490152	136490175	X	-	26627737	RPE1	viability after 9 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.28415394730256327	[1042]	[127,448]	-2	hSpCas9	negative selection	1173853
136490463	136490486	X	+	26627737	RPE1	viability after 9 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.2753488734204228	[837]	[376,967]	7	hSpCas9	negative selection	1173854
136492153	136492176	X	-	26627737	RPE1	viability after 9 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.7160288969702563	[1173]	[570,645]	5	hSpCas9	negative selection	1173855
136492249	136492272	X	+	26627737	RPE1	viability after 9 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.23191906013765973	[1796]	[468,491]	-2	hSpCas9	negative selection	1173856
136492267	136492290	X	-	26627737	RPE1	viability after 9 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.04708716367748833	[1125]	[313,428]	0	hSpCas9	negative selection	1173857
136488492	136488515	X	-	26627737	RPE1	viability after 12 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.9175048719501913	[305]	[147,162]	6	hSpCas9	negative selection	1256167
136490152	136490175	X	-	26627737	RPE1	viability after 12 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.38490576497746826	[1042]	[217,210]	-3	hSpCas9	negative selection	1256168
136490463	136490486	X	+	26627737	RPE1	viability after 12 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.201158049310576	[837]	[369,673]	7	hSpCas9	negative selection	1256169
136492153	136492176	X	-	26627737	RPE1	viability after 12 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.9555414911490935	[1173]	[719,496]	6	hSpCas9	negative selection	1256170
136492249	136492272	X	+	26627737	RPE1	viability after 12 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.09544914305256236	[1796]	[549,347]	0	hSpCas9	negative selection	1256171
136492267	136492290	X	-	26627737	RPE1	viability after 12 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.08785933103056787	[1125]	[287,356]	0	hSpCas9	negative selection	1256172
136488492	136488515	X	-	26627737	RPE1	viability after 15 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	1.036403975144651	[305]	[174,179]	6	hSpCas9	negative selection	1338482
136490152	136490175	X	-	26627737	RPE1	viability after 15 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.08018819653128467	[1042]	[260,360]	0	hSpCas9	negative selection	1338483
136490463	136490486	X	+	26627737	RPE1	viability after 15 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.128613732587829	[837]	[528,507]	6	hSpCas9	negative selection	1338484
136492153	136492176	X	-	26627737	RPE1	viability after 15 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.688403058803157	[1173]	[693,381]	4	hSpCas9	negative selection	1338485
136492249	136492272	X	+	26627737	RPE1	viability after 15 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	0.035958482396294844	[1796]	[708,339]	0	hSpCas9	negative selection	1338486
136492267	136492290	X	-	26627737	RPE1	viability after 15 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.4543338621886037	[1125]	[468,404]	3	hSpCas9	negative selection	1338487
136488492	136488515	X	-	26627737	RPE1	viability after 18 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.5246253993729094	[305]	[141,93]	3	hSpCas9	negative selection	1420797
136490152	136490175	X	-	26627737	RPE1	viability after 18 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.2175682005264294	[1042]	[214,270]	-1	hSpCas9	negative selection	1420798
136490463	136490486	X	+	26627737	RPE1	viability after 18 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.0983606339391858	[837]	[504,461]	6	hSpCas9	negative selection	1420799
136492153	136492176	X	-	26627737	RPE1	viability after 18 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.7158971854222945	[1173]	[691,336]	4	hSpCas9	negative selection	1420800
136492249	136492272	X	+	26627737	RPE1	viability after 18 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	0.10466622405288639	[1796]	[650,382]	0	hSpCas9	negative selection	1420801
136492267	136492290	X	-	26627737	RPE1	viability after 18 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.7595382873408617	[1125]	[468,562]	4	hSpCas9	negative selection	1420802
136488492	136488515	X	-	26627737	HeLa	viability after 8 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.6202223638675783	[262]	[178,211,139]	5	hSpCas9	negative selection	1503112
136490152	136490175	X	-	26627737	HeLa	viability after 8 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.398726372179805	[778]	[281,343,157]	-4	hSpCas9	negative selection	1503113
136490463	136490486	X	+	26627737	HeLa	viability after 8 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.7617468301010497	[316]	[792,319,368]	9	hSpCas9	negative selection	1503114
136492153	136492176	X	-	26627737	HeLa	viability after 8 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.023412751015595923	[1218]	[603,449,574]	0	hSpCas9	negative selection	1503115
136492249	136492272	X	+	26627737	HeLa	viability after 8 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.8521515559597832	[822]	[149,213,218]	-7	hSpCas9	negative selection	1503116
136492267	136492290	X	-	26627737	HeLa	viability after 8 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	-0.28176571684320095	[615]	[340,185,164]	-3	hSpCas9	negative selection	1503117
136488492	136488515	X	-	26627737	HeLa	viability after 12 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.1183292656138421	[262]	[116,135,98]	1	hSpCas9	negative selection	1585427
136490152	136490175	X	-	26627737	HeLa	viability after 12 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.3554373174944928	[778]	[197,235,320]	-3	hSpCas9	negative selection	1585428
136490463	136490486	X	+	26627737	HeLa	viability after 12 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.4000534841359422	[316]	[437,306,298]	8	hSpCas9	negative selection	1585429
136492153	136492176	X	-	26627737	HeLa	viability after 12 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.2298364142000433	[1218]	[461,369,463]	-2	hSpCas9	negative selection	1585430
136492249	136492272	X	+	26627737	HeLa	viability after 12 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.20423514965940603	[822]	[317,269,300]	-2	hSpCas9	negative selection	1585431
136492267	136492290	X	-	26627737	HeLa	viability after 12 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	-0.8056702039637309	[615]	[195,35,217]	-6	hSpCas9	negative selection	1585432
136488492	136488515	X	-	26627737	HeLa	viability after 15 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.9671207943653238	[262]	[143,308,172]	7	hSpCas9	negative selection	1667742
136490152	136490175	X	-	26627737	HeLa	viability after 15 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.10291154299572913	[778]	[343,212,330]	-1	hSpCas9	negative selection	1667743
136490463	136490486	X	+	26627737	HeLa	viability after 15 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.7523634027446904	[316]	[601,279,418]	9	hSpCas9	negative selection	1667744
136492153	136492176	X	-	26627737	HeLa	viability after 15 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.04702987724964758	[1218]	[582,408,444]	0	hSpCas9	negative selection	1667745
136492249	136492272	X	+	26627737	HeLa	viability after 15 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.44363556083766	[822]	[100,271,377]	-4	hSpCas9	negative selection	1667746
136492267	136492290	X	-	26627737	HeLa	viability after 15 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	-0.8982141413062645	[615]	[249,67,79]	-7	hSpCas9	negative selection	1667747
136488492	136488515	X	-	26627737	HeLa	viability after 18 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.9808490793200999	[262]	[101,253,172]	7	hSpCas9	negative selection	1750057
136490152	136490175	X	-	26627737	HeLa	viability after 18 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.15224132280514324	[778]	[222,161,330]	-1	hSpCas9	negative selection	1750058
136490463	136490486	X	+	26627737	HeLa	viability after 18 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.7601885998973963	[316]	[413,224,418]	9	hSpCas9	negative selection	1750059
136492153	136492176	X	-	26627737	HeLa	viability after 18 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.061780164371141755	[1218]	[382,336,444]	0	hSpCas9	negative selection	1750060
136492249	136492272	X	+	26627737	HeLa	viability after 18 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.4213669942633381	[822]	[72,227,377]	-4	hSpCas9	negative selection	1750061
136492267	136492290	X	-	26627737	HeLa	viability after 18 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	-0.8730052632057795	[615]	[170,57,79]	-6	hSpCas9	negative selection	1750062
136488492	136488515	X	-	26627737	HCT116	viability after 6 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	1.2707202044179668	[399]	[337,48]	6	hSpCas9	negative selection	1832372
136490152	136490175	X	-	26627737	HCT116	viability after 6 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.7100964353731031	[1020]	[667,38]	4	hSpCas9	negative selection	1832373
136490463	136490486	X	+	26627737	HCT116	viability after 6 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.9749368056472599	[1975]	[32,226]	-5	hSpCas9	negative selection	1832374
136492153	136492176	X	-	26627737	HCT116	viability after 6 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.07425000139907523	[1601]	[181,310]	0	hSpCas9	negative selection	1832375
136492249	136492272	X	+	26627737	HCT116	viability after 6 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	1.308892440868311	[1298]	[746,372]	7	hSpCas9	negative selection	1832376
136492267	136492290	X	-	26627737	HCT116	viability after 6 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	-0.332296184956953	[755]	[105,87]	-2	hSpCas9	negative selection	1832377
136488492	136488515	X	-	26627737	HCT116	viability after 8 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.2771657935042587	[201]	[102,76,222]	3	hSpCas9	negative selection	1914687
136490152	136490175	X	-	26627737	HCT116	viability after 8 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.2768696546393561	[449]	[273,260,364]	3	hSpCas9	negative selection	1914688
136490463	136490486	X	+	26627737	HCT116	viability after 8 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.6783015294695114	[429]	[358,469,308]	6	hSpCas9	negative selection	1914689
136492153	136492176	X	-	26627737	HCT116	viability after 8 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.49187867087161574	[547]	[394,420,456]	5	hSpCas9	negative selection	1914690
136492249	136492272	X	+	26627737	HCT116	viability after 8 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.0855063400196222	[615]	[361,323,274]	-1	hSpCas9	negative selection	1914691
136492267	136492290	X	-	26627737	HCT116	viability after 8 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	-0.05504660114498806	[322]	[130,273,108]	0	hSpCas9	negative selection	1914692
136488492	136488515	X	-	26627737	HCT116	viability after 9 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-1.0715470231664987	[399]	[42,56]	-6	hSpCas9	negative selection	1997002
136490152	136490175	X	-	26627737	HCT116	viability after 9 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.2251973134444616	[1020]	[149,298]	-1	hSpCas9	negative selection	1997003
136490463	136490486	X	+	26627737	HCT116	viability after 9 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.10281911185729542	[1975]	[511,474]	0	hSpCas9	negative selection	1997004
136492153	136492176	X	-	26627737	HCT116	viability after 9 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.5885436835122442	[1601]	[465,140]	-4	hSpCas9	negative selection	1997005
136492249	136492272	X	+	26627737	HCT116	viability after 9 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.615546130092191	[1298]	[298,168]	-4	hSpCas9	negative selection	1997006
136492267	136492290	X	-	26627737	HCT116	viability after 9 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.8832332640441924	[755]	[349,389]	6	hSpCas9	negative selection	1997007
136488492	136488515	X	-	26627737	HCT116	viability after 12 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.4423042952666222	[201]	[77,61,93]	-5	hSpCas9	negative selection	2079317
136490152	136490175	X	-	26627737	HCT116	viability after 12 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.3743991632756438	[449]	[311,380,227]	4	hSpCas9	negative selection	2079318
136490463	136490486	X	+	26627737	HCT116	viability after 12 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.8343000800163476	[429]	[478,317,402]	7	hSpCas9	negative selection	2079319
136492153	136492176	X	-	26627737	HCT116	viability after 12 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.6610474735692343	[547]	[444,494,427]	6	hSpCas9	negative selection	2079320
136492249	136492272	X	+	26627737	HCT116	viability after 12 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.052153127822619605	[615]	[298,276,360]	0	hSpCas9	negative selection	2079321
136492267	136492290	X	-	26627737	HCT116	viability after 12 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.1431409894588801	[322]	[149,160,253]	1	hSpCas9	negative selection	2079322
136488492	136488515	X	-	26627737	HCT116	viability after 15 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.41396576311573774	[201]	[161,98,202]	4	hSpCas9	negative selection	2161632
136490152	136490175	X	-	26627737	HCT116	viability after 15 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.37402016142440564	[449]	[409,277,325]	3	hSpCas9	negative selection	2161633
136490463	136490486	X	+	26627737	HCT116	viability after 15 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.7920511617621961	[429]	[589,321,390]	7	hSpCas9	negative selection	2161634
136492153	136492176	X	-	26627737	HCT116	viability after 15 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.6748292075708148	[547]	[616,469,434]	6	hSpCas9	negative selection	2161635
136492249	136492272	X	+	26627737	HCT116	viability after 15 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	0.09825442428865272	[615]	[351,331,447]	1	hSpCas9	negative selection	2161636
136492267	136492290	X	-	26627737	HCT116	viability after 15 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	-0.0313927437863272	[322]	[159,125,254]	0	hSpCas9	negative selection	2161637
136488492	136488515	X	-	26627737	HCT116	viability after 18 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.5670675195271715	[201]	[129,73,238]	5	hSpCas9	negative selection	2243947
136490152	136490175	X	-	26627737	HCT116	viability after 18 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.5530938663201913	[449]	[322,279,358]	4	hSpCas9	negative selection	2243948
136490463	136490486	X	+	26627737	HCT116	viability after 18 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.0888560253217472	[429]	[520,345,466]	8	hSpCas9	negative selection	2243949
136492153	136492176	X	-	26627737	HCT116	viability after 18 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.733775699141117	[547]	[349,543,419]	6	hSpCas9	negative selection	2243950
136492249	136492272	X	+	26627737	HCT116	viability after 18 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	0.2539120726890651	[615]	[314,228,537]	2	hSpCas9	negative selection	2243951
136492267	136492290	X	-	26627737	HCT116	viability after 18 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	-0.6755233392467884	[322]	[55,108,128]	-6	hSpCas9	negative selection	2243952
136488438	136488461	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	0.2676756963563725	[3,3]	[2,4]	6	hSpCas9	positive selection	2973755
136488274	136488297	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATGCTGTGATCATTTCAGTGG	BRS3	ENSG00000102239	0.2592090399812529	[5,6]	[6,5]	5	hSpCas9	positive selection	2973756
136488438	136488461	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	-0.09553519598492084	[3,3]	[2,1]	-1	hSpCas9	positive selection	3041613
136488274	136488297	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATGCTGTGATCATTTCAGTGG	BRS3	ENSG00000102239	0.15791705721944582	[5,5]	[6,3]	3	hSpCas9	positive selection	3041614
136490463	136490486		+	24336571	A375	resistance to PLX after 7 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.014924071363968339	[16,14]	[14,15]	0	hSpCas9	positive selection	3151668
136490439	136490462		+	24336571	A375	resistance to PLX after 7 days	CACCCTGAACATACCTACTGAGG	BRS3	ENSG00000102239	0.09965973317191693	[9,10]	[9,11]	3	hSpCas9	positive selection	3151676
136488438	136488461		-	24336571	A375	resistance to PLX after 7 days	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	0.20374268434914655	[12,15]	[15,16]	6	hSpCas9	positive selection	3151687
136488527	136488550		+	24336571	A375	resistance to PLX after 7 days	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.3505827148037826	[7,10]	[7,5]	-8	hSpCas9	positive selection	3151698
136490463	136490486		+	24336571	A375	resistance to PLX after 14 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.745816605063585	[8,15]	[8,9]	6	hSpCas9	positive selection	3209461
136490439	136490462		+	24336571	A375	resistance to PLX after 14 days	CACCCTGAACATACCTACTGAGG	BRS3	ENSG00000102239	0.20234056577797585	[13,14]	[6,7]	2	hSpCas9	positive selection	3209469
136488438	136488461		-	24336571	A375	resistance to PLX after 14 days	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	-0.30016930522258106	[15,15]	[5,5]	-3	hSpCas9	positive selection	3209480
136488527	136488550		+	24336571	A375	resistance to PLX after 14 days	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.48944645762878264	[13,4]	[2,1]	-6	hSpCas9	positive selection	3209491
136490463	136490486		+	24336571	A375	viability after 7 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.26622069305010654	[13]	[16,14]	4	hSpCas9	negative selection	3267254
136490439	136490462		+	24336571	A375	viability after 7 days	CACCCTGAACATACCTACTGAGG	BRS3	ENSG00000102239	0.0005574827709995955	[10]	[9,10]	0	hSpCas9	negative selection	3267262
136488438	136488461		-	24336571	A375	viability after 7 days	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	0.12495190474721753	[13]	[12,15]	2	hSpCas9	negative selection	3267273
136488527	136488550		+	24336571	A375	viability after 7 days	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.43241429032810536	[13]	[7,10]	-6	hSpCas9	negative selection	3267284
136490463	136490486		+	24336571	A375	viability after 14 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.08088470872942988	[13]	[8,15]	-1	hSpCas9	negative selection	3325047
136490439	136490462		+	24336571	A375	viability after 14 days	CACCCTGAACATACCTACTGAGG	BRS3	ENSG00000102239	0.44298943127797863	[10]	[13,14]	5	hSpCas9	negative selection	3325055
136488438	136488461		-	24336571	A375	viability after 14 days	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	0.3169304470360272	[13]	[15,15]	4	hSpCas9	negative selection	3325066
136488527	136488550		+	24336571	A375	viability after 14 days	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.44446182037239185	[13]	[13,4]	-5	hSpCas9	negative selection	3325077
136492319	136492342	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	-0.9454538375705503	[314,273]	[0,0]	-6	hSpCas9	positive selection	3339125
136491984	136492007	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.29584814406881166	[143,104]	[0,0]	1	hSpCas9	positive selection	3339126
136490463	136490486	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.9452144177732112	[72,85]	[0,0]	4	hSpCas9	positive selection	3339127
136488527	136488550	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.6674862921599458	[242,242]	[0,0]	-4	hSpCas9	positive selection	3358366
136490469	136490492	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	5.978899755195059	[244,244]	[100,100]	9	hSpCas9	positive selection	3358367
136488456	136488479	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.29726264023180216	[187,187]	[0,0]	-2	hSpCas9	positive selection	3358368
136488492	136488515	X	-	26780180	HT29	viability (Avana library 4 designs)	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.516330904013045	[]	[]	2	hSpCas9	negative selection	3409954
136488438	136488461	X	-	26780180	HT29	viability (Avana library 4 designs)	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	0.261642458990729	[]	[]	0	hSpCas9	negative selection	3409955
136488378	136488401	X	-	26780180	HT29	viability (Avana library 4 designs)	GTAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.155062024808781	[]	[]	0	hSpCas9	negative selection	3409956
136488273	136488296	X	+	26780180	HT29	viability (Avana library 4 designs)	TTATGCTGTGATCATTTCAGTGG	BRS3	ENSG00000102239	-0.353011365371561	[]	[]	-5	hSpCas9	negative selection	3409957
136488378	136488401	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	-1.52701317713096	[]	[]	-2	hSpCas9	negative selection	3484220
136488492	136488515	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.0877434609328615	[]	[]	0	hSpCas9	negative selection	3484221
136488438	136488461	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	2.38159750494874	[]	[]	3	hSpCas9	negative selection	3484222
136488273	136488296	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATGCTGTGATCATTTCAGTGG	BRS3	ENSG00000102239	-6.67422492002852	[]	[]	-6	hSpCas9	negative selection	3484223
136488378	136488401	X	-	26780180	A375	viability (Avana lentiGuide)	GTAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	-5.50568726061091	[]	[]	-8	hSpCas9	negative selection	3592879
136488492	136488515	X	-	26780180	A375	viability (Avana lentiGuide)	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-2.09769799102574	[]	[]	-4	hSpCas9	negative selection	3592880
136488438	136488461	X	-	26780180	A375	viability (Avana lentiGuide)	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	-2.02945347216627	[]	[]	-3	hSpCas9	negative selection	3592881
136488273	136488296	X	+	26780180	A375	viability (Avana lentiGuide)	TTATGCTGTGATCATTTCAGTGG	BRS3	ENSG00000102239	-2.01474480783321	[]	[]	-3	hSpCas9	negative selection	3592882
136488378	136488401	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	-0.24041791557020542	[7]	[6,5]	-4	hSpCas9	positive selection	3701538
136488492	136488515	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.24526419557026222	[5]	[4,3]	-4	hSpCas9	positive selection	3701539
136488438	136488461	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	-0.14287702086786797	[4]	[5,2]	-2	hSpCas9	positive selection	3701540
136488273	136488296	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATGCTGTGATCATTTCAGTGG	BRS3	ENSG00000102239	-0.2008100719048025	[8]	[7,6]	-3	hSpCas9	positive selection	3701541
136488378	136488401	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.23072154853253685	[6]	[6,6]	6	hSpCas9	positive selection	3810145
136488492	136488515	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.33592119417673283	[6]	[3,4]	-4	hSpCas9	positive selection	3810146
136488438	136488461	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	0.24749294655728787	[5]	[5,5]	6	hSpCas9	positive selection	3810147
136488273	136488296	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATGCTGTGATCATTTCAGTGG	BRS3	ENSG00000102239	0.3175596518086657	[7]	[8,7]	8	hSpCas9	positive selection	3810148
136490463	136490486	X	+	26780180	A375	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.988640425670188	[]	[]	4	hSpCas9	negative selection	3918418
136492319	136492342	X	+	26780180	A375	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.402242768889681	[]	[]	1	hSpCas9	negative selection	3918419
136491984	136492007	X	-	26780180	A375	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.666224566836601	[]	[]	2	hSpCas9	negative selection	3918420
136488456	136488479	X	+	26780180	A375	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.917067211528884	[]	[]	4	hSpCas9	negative selection	3918421
136488527	136488550	X	+	26780180	A375	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.538442259220641	[]	[]	1	hSpCas9	negative selection	3918422
136490469	136490492	X	-	26780180	A375	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.678359673091566	[]	[]	2	hSpCas9	negative selection	3918423
136490463	136490486	X	+	26780180	HT29	viability (GeCKOv2 library)	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	1.20834887900583	[]	[]	6	hSpCas9	negative selection	4026384
136492319	136492342	X	+	26780180	HT29	viability (GeCKOv2 library)	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	1.0318040905834	[]	[]	5	hSpCas9	negative selection	4026385
136491984	136492007	X	-	26780180	HT29	viability (GeCKOv2 library)	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.650460050872942	[]	[]	2	hSpCas9	negative selection	4026386
136488456	136488479	X	+	26780180	HT29	viability (GeCKOv2 library)	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	1.36563221580186	[]	[]	7	hSpCas9	negative selection	4026387
136488527	136488550	X	+	26780180	HT29	viability (GeCKOv2 library)	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	1.28190090416039	[]	[]	6	hSpCas9	negative selection	4026388
136490469	136490492	X	-	26780180	HT29	viability (GeCKOv2 library)	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.741061394283608	[]	[]	3	hSpCas9	negative selection	4026389
136490463	136490486	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.0964300444027647	[4]	[2,3]	2	hSpCas9	positive selection	4178185
136490439	136490462	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACCCTGAACATACCTACTGAGG	BRS3	ENSG00000102239	0.5381729682533326	[2]	[2,2]	9	hSpCas9	positive selection	4178196
136488438	136488461	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	-0.12340267625257603	[3]	[1,2]	-3	hSpCas9	positive selection	4178207
136488527	136488550	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.35208449146786513	[2]	[3,1]	8	hSpCas9	positive selection	4178218
136490463	136490486	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.7085617355748489	[2]	[3,2,0,0]	4	hSpCas9	positive selection	4242207
136490439	136490462	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACCCTGAACATACCTACTGAGG	BRS3	ENSG00000102239	0.02761289373246692	[4]	[3,0,2,0]	0	hSpCas9	positive selection	4242218
136488438	136488461	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAACAGCCATCCTTCTGCAAGG	BRS3	ENSG00000102239	0.8754017808957201	[4]	[2,3,0,3]	6	hSpCas9	positive selection	4242229
136488527	136488550	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.5400571974125714	[3]	[0,2,0,0]	-7	hSpCas9	positive selection	4242240
136492319	136492342	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.26113772714074546	[4]	[4,4]	5	hSpCas9	positive selection	4258546
136491984	136492007	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.17334662968872427	[3]	[3,2]	3	hSpCas9	positive selection	4258547
136490463	136490486	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.21617679728621308	[2]	[1,0]	-4	hSpCas9	positive selection	4258548
136488527	136488550	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.10070930442829842	[3]	[2,1]	-2	hSpCas9	positive selection	4322830
136490469	136490492	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.47355424207019703	[3]	[3,4]	8	hSpCas9	positive selection	4322831
136488456	136488479	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.424627199651645	[3]	[4,2]	8	hSpCas9	positive selection	4322832
136488208	136488230	X	+	27760321	OCIAML3	viability	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	0.5566044880793424	[259,205]	[294,228]	6	hSpCas9	negative selection	4382331
136488260	136488282	X	-	27760321	OCIAML3	viability	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.19519984139032864	[1,0]	[0,0]	-2	hSpCas9	negative selection	4382332
136488378	136488400	X	-	27760321	OCIAML3	viability	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	1.042989489110931	[205,179]	[318,298]	9	hSpCas9	negative selection	4382333
136488418	136488440	X	-	27760321	OCIAML3	viability	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.5706573239494099	[675,595]	[607,905]	6	hSpCas9	negative selection	4382334
136488528	136488550	X	+	27760321	OCIAML3	viability	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.13386821179218597	[507,472]	[324,381]	-1	hSpCas9	negative selection	4382335
136488208	136488230	X	+	27760321	OCIAML2	viability	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	-0.42667794760130007	[259,205]	[128,152]	-5	hSpCas9	negative selection	4465794
136488260	136488282	X	-	27760321	OCIAML2	viability	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.24394520665537733	[1,0]	[0,0]	-3	hSpCas9	negative selection	4465795
136488378	136488400	X	-	27760321	OCIAML2	viability	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.5239685087670131	[205,179]	[182,277]	7	hSpCas9	negative selection	4465796
136488418	136488440	X	-	27760321	OCIAML2	viability	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.4822651246410232	[675,595]	[662,788]	6	hSpCas9	negative selection	4465797
136488528	136488550	X	+	27760321	OCIAML2	viability	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.6017272526809782	[507,472]	[569,644]	7	hSpCas9	negative selection	4465798
136488208	136488230	X	+	27760321	MV411	viability	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	1.9157802359076004	[259,205]	[743,324]	9	hSpCas9	negative selection	4549257
136488260	136488282	X	-	27760321	MV411	viability	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	0.049878727524353295	[1,0]	[0,0]	0	hSpCas9	negative selection	4549258
136488378	136488400	X	-	27760321	MV411	viability	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	1.639790656692576	[205,179]	[385,410]	9	hSpCas9	negative selection	4549259
136488418	136488440	X	-	27760321	MV411	viability	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.7847669571751792	[675,595]	[602,899]	6	hSpCas9	negative selection	4549260
136488528	136488550	X	+	27760321	MV411	viability	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.4441119410363795	[507,472]	[581,227]	3	hSpCas9	negative selection	4549261
136488208	136488230	X	+	27760321	HL60	viability	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	-0.4670956888826676	[259,205]	[180,89]	-5	hSpCas9	negative selection	4632720
136488260	136488282	X	-	27760321	HL60	viability	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.2579914342697833	[1,0]	[0,0]	-3	hSpCas9	negative selection	4632721
136488378	136488400	X	-	27760321	HL60	viability	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.7280464380862642	[205,179]	[278,240]	8	hSpCas9	negative selection	4632722
136488418	136488440	X	-	27760321	HL60	viability	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.5197014512852103	[675,595]	[674,815]	6	hSpCas9	negative selection	4632723
136488528	136488550	X	+	27760321	HL60	viability	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.07805711092922693	[507,472]	[409,436]	1	hSpCas9	negative selection	4632724
136488208	136488230	X	+	27760321	HT1080	viability	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	-1.2558599547491647	[205,160]	[32,27]	-5	hSpCas9	negative selection	4716183
136488260	136488282	X	-	27760321	HT1080	viability	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4716184
136488378	136488400	X	-	27760321	HT1080	viability	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	1.2201270939404132	[179,140]	[74,229]	6	hSpCas9	negative selection	4716185
136488418	136488440	X	-	27760321	HT1080	viability	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	-0.7398319498941568	[595,464]	[116,136]	-3	hSpCas9	negative selection	4716186
136488528	136488550	X	+	27760321	HT1080	viability	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.6948301628688662	[472,368]	[312,225]	4	hSpCas9	negative selection	4716187
136488208	136488230	X	+	27760321	HT29	viability after 7 days	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	0.7135754579219247	[205,160]	[356,540,261]	9	hSpCas9	negative selection	4799646
136488260	136488282	X	-	27760321	HT29	viability after 7 days	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4799647
136488378	136488400	X	-	27760321	HT29	viability after 7 days	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	-0.04036857240735792	[179,140]	[182,173,240]	0	hSpCas9	negative selection	4799648
136488418	136488440	X	-	27760321	HT29	viability after 7 days	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.19357784424855273	[595,464]	[1008,756,610]	3	hSpCas9	negative selection	4799649
136488528	136488550	X	+	27760321	HT29	viability after 7 days	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.09804731406608361	[472,368]	[589,387,548]	-1	hSpCas9	negative selection	4799650
136488208	136488230	X	+	27760321	HT29	viability after 25 days	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	0.6228323491462819	[205,160]	[212,441,319]	7	hSpCas9	negative selection	4883109
136488260	136488282	X	-	27760321	HT29	viability after 25 days	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4883110
136488378	136488400	X	-	27760321	HT29	viability after 25 days	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.032961523295651274	[179,140]	[193,149,221]	0	hSpCas9	negative selection	4883111
136488418	136488440	X	-	27760321	HT29	viability after 25 days	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.4186921843683131	[595,464]	[804,532,1124]	4	hSpCas9	negative selection	4883112
136488528	136488550	X	+	27760321	HT29	viability after 25 days	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.2900622593646327	[472,368]	[417,583,793]	3	hSpCas9	negative selection	4883113
136488208	136488230	X	+	27760321	HT29	viability after 22 days	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	0.22880014924145253	[205,160]	[197,425,121]	2	hSpCas9	negative selection	4966572
136488260	136488282	X	-	27760321	HT29	viability after 22 days	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4966573
136488378	136488400	X	-	27760321	HT29	viability after 22 days	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.02967400202488535	[179,140]	[206,155,204]	0	hSpCas9	negative selection	4966574
136488418	136488440	X	-	27760321	HT29	viability after 22 days	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.07853806692200438	[595,464]	[665,651,623]	0	hSpCas9	negative selection	4966575
136488528	136488550	X	+	27760321	HT29	viability after 22 days	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.4807742886283939	[472,368]	[818,606,606]	5	hSpCas9	negative selection	4966576
136488208	136488230	X	+	27760321	HT29	viability after 19 days	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	0.2697382860161146	[205,160]	[401,319,59]	2	hSpCas9	negative selection	5050035
136488260	136488282	X	-	27760321	HT29	viability after 19 days	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5050036
136488378	136488400	X	-	27760321	HT29	viability after 19 days	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.29923952431248846	[179,140]	[433,162,106]	3	hSpCas9	negative selection	5050037
136488418	136488440	X	-	27760321	HT29	viability after 19 days	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.23937848465576195	[595,464]	[850,641,670]	2	hSpCas9	negative selection	5050038
136488528	136488550	X	+	27760321	HT29	viability after 19 days	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.34658214656145037	[472,368]	[384,1097,339]	3	hSpCas9	negative selection	5050039
136488208	136488230	X	+	27760321	HT29	viability after 16 days	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	-0.6668911420053449	[205,160]	[62,231,83]	-6	hSpCas9	negative selection	5133498
136488260	136488282	X	-	27760321	HT29	viability after 16 days	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5133499
136488378	136488400	X	-	27760321	HT29	viability after 16 days	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.8920782906396922	[179,140]	[340,319,339]	9	hSpCas9	negative selection	5133500
136488418	136488440	X	-	27760321	HT29	viability after 16 days	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.39377183199406063	[595,464]	[1046,604,716]	4	hSpCas9	negative selection	5133501
136488528	136488550	X	+	27760321	HT29	viability after 16 days	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.43741240865865094	[472,368]	[438,659,794]	5	hSpCas9	negative selection	5133502
136488208	136488230	X	+	27760321	HT29	viability after 13 days	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	-0.18606478161218987	[205,160]	[216,168,175]	-2	hSpCas9	negative selection	5216961
136488260	136488282	X	-	27760321	HT29	viability after 13 days	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5216962
136488378	136488400	X	-	27760321	HT29	viability after 13 days	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.16830271997475643	[179,140]	[160,292,175]	2	hSpCas9	negative selection	5216963
136488418	136488440	X	-	27760321	HT29	viability after 13 days	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.3026711934320343	[595,464]	[788,489,983]	4	hSpCas9	negative selection	5216964
136488528	136488550	X	+	27760321	HT29	viability after 13 days	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.018413266849293147	[472,368]	[435,671,382]	0	hSpCas9	negative selection	5216965
136488208	136488230	X	+	27760321	HT29	viability after 10 days	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	-0.19967021106863703	[205,160]	[197,209,190]	-3	hSpCas9	negative selection	5300424
136488260	136488282	X	-	27760321	HT29	viability after 10 days	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5300425
136488378	136488400	X	-	27760321	HT29	viability after 10 days	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.3227677432915875	[179,140]	[167,346,239]	4	hSpCas9	negative selection	5300426
136488418	136488440	X	-	27760321	HT29	viability after 10 days	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.03559379633706994	[595,464]	[786,438,800]	0	hSpCas9	negative selection	5300427
136488528	136488550	X	+	27760321	HT29	viability after 10 days	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.10182179605512603	[472,368]	[561,602,528]	1	hSpCas9	negative selection	5300428
136488208	136488230	X	+	27760321	MOLM13	viability	ACAAATAAAGGATGGAGCGGGG	BRS3	ENSG00000102239	0.2678933864718258	[259,205]	[38,257]	1	hSpCas9	negative selection	5383887
136488260	136488282	X	-	27760321	MOLM13	viability	ACAGCATAAGTAATATAGATGG	BRS3	ENSG00000102239	0.27593554035194856	[1,0]	[0,0]	2	hSpCas9	negative selection	5383888
136488378	136488400	X	-	27760321	MOLM13	viability	TAAAAGATCTCCAAAAGCCAGG	BRS3	ENSG00000102239	0.9976717314299799	[205,179]	[284,158]	7	hSpCas9	negative selection	5383889
136488418	136488440	X	-	27760321	MOLM13	viability	GGTAGTGAGTTGCATCCACTGG	BRS3	ENSG00000102239	0.06285479011623107	[675,595]	[365,380]	0	hSpCas9	negative selection	5383890
136488528	136488550	X	+	27760321	MOLM13	viability	AACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.47030203675321014	[507,472]	[557,234]	3	hSpCas9	negative selection	5383891
136487944	136487967	X	+	27661255	K562	viability	GACACACAGAACTGAAGCAAAGG	BRS3	ENSG00000102239	0.042227848563121506	[1047,1016]	[927,782]	1	dCas9-KRAB	negative selection	5465561
136488456	136488479	X	+	27661255	K562	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.16261758929571724	[796,923]	[843,701]	5	dCas9-KRAB	negative selection	5465562
136492319	136492342	X	+	27260156	BXPC3	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	-0.03759920883413659	[1512]	[1452,1518,1455,1762]	-1	hSpCas9	negative selection	5531006
136491984	136492007	X	-	27260156	BXPC3	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.14162066356918868	[595]	[522,682,769,802]	3	hSpCas9	negative selection	5531007
136490463	136490486	X	+	27260156	BXPC3	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.05016534208378276	[250]	[199,231,340,246]	-1	hSpCas9	negative selection	5531008
136488527	136488550	X	+	27260156	BXPC3	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.3260377893587054	[705]	[524,523,673,647]	-6	hSpCas9	negative selection	5595290
136490469	136490492	X	-	27260156	BXPC3	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.03113737497011715	[742]	[786,633,679,962]	0	hSpCas9	negative selection	5595291
136488456	136488479	X	+	27260156	BXPC3	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.004982310049043509	[550]	[428,528,747,612]	0	hSpCas9	negative selection	5595292
136492319	136492342	X	+	27260156	A673	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	-0.1621455387808397	[1512]	[1880,1566,1536,1532]	-4	hSpCas9	negative selection	5652257
136491984	136492007	X	-	27260156	A673	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.1880364705910607	[595]	[864,747,833,819]	4	hSpCas9	negative selection	5652258
136490463	136490486	X	+	27260156	A673	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.11301955513802597	[250]	[277,259,273,303]	-3	hSpCas9	negative selection	5652259
136488527	136488550	X	+	27260156	A673	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.37741470017512696	[705]	[725,696,575,615]	-7	hSpCas9	negative selection	5716541
136490469	136490492	X	-	27260156	A673	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.10392514525827024	[742]	[917,816,807,783]	-3	hSpCas9	negative selection	5716542
136488456	136488479	X	+	27260156	A673	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.06220000766573325	[550]	[725,595,567,656]	-1	hSpCas9	negative selection	5716543
136492319	136492342	X	+	27260156	A375	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.2408762583338362	[1512]	[2125,2302,2087,1882]	3	hSpCas9	negative selection	5773508
136491984	136492007	X	-	27260156	A375	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.3916110160394383	[595]	[900,864,1161,735]	6	hSpCas9	negative selection	5773509
136490463	136490486	X	+	27260156	A375	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.30359340697987447	[250]	[334,467,355,307]	4	hSpCas9	negative selection	5773510
136488527	136488550	X	+	27260156	A375	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.17629761693548518	[705]	[1055,948,791,929]	2	hSpCas9	negative selection	5837792
136490469	136490492	X	-	27260156	A375	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.131862374135998	[742]	[1067,1054,961,753]	2	hSpCas9	negative selection	5837793
136488456	136488479	X	+	27260156	A375	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.27797607618319176	[550]	[911,668,735,785]	4	hSpCas9	negative selection	5837794
136492319	136492342	X	+	27260156	COLO741	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.09992064333345185	[1512]	[2332,1919,1985]	2	hSpCas9	negative selection	5894759
136491984	136492007	X	-	27260156	COLO741	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.24077174599828483	[595]	[835,953,901]	5	hSpCas9	negative selection	5894760
136490463	136490486	X	+	27260156	COLO741	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.20406801940235053	[250]	[374,461,277]	4	hSpCas9	negative selection	5894761
136488527	136488550	X	+	27260156	COLO741	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.2249716953759085	[705]	[959,732,645]	-5	hSpCas9	negative selection	5959043
136490469	136490492	X	-	27260156	COLO741	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.03434548667956183	[742]	[1159,839,932]	0	hSpCas9	negative selection	5959044
136488456	136488479	X	+	27260156	COLO741	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.18624705042352438	[550]	[643,761,462]	-4	hSpCas9	negative selection	5959045
136492319	136492342	X	+	27260156	CAL120	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.0923038804353471	[1512]	[1879,2421,1704]	1	hSpCas9	negative selection	6016010
136491984	136492007	X	-	27260156	CAL120	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.3960026629987327	[595]	[995,826,1104]	6	hSpCas9	negative selection	6016011
136490463	136490486	X	+	27260156	CAL120	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.023937142858008187	[250]	[243,351,344]	0	hSpCas9	negative selection	6016012
136488527	136488550	X	+	27260156	CAL120	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.09765746011707865	[705]	[1220,640,998]	1	hSpCas9	negative selection	6080294
136490469	136490492	X	-	27260156	CAL120	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.04521773528399187	[742]	[1602,720,640]	0	hSpCas9	negative selection	6080295
136488456	136488479	X	+	27260156	CAL120	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.17616149247559917	[550]	[918,902,527]	2	hSpCas9	negative selection	6080296
136492319	136492342	X	+	27260156	CADOES1	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.0949127070110285	[1512]	[1440,1520,1486,1564]	1	hSpCas9	negative selection	6137261
136491984	136492007	X	-	27260156	CADOES1	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.27774042558785034	[595]	[610,743,540,796]	5	hSpCas9	negative selection	6137262
136490463	136490486	X	+	27260156	CADOES1	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.04309941900267744	[250]	[217,191,235,318]	0	hSpCas9	negative selection	6137263
136488527	136488550	X	+	27260156	CADOES1	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.2990361266304761	[705]	[736,727,764,1008]	5	hSpCas9	negative selection	6201545
136490469	136490492	X	-	27260156	CADOES1	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.30582011960793176	[742]	[975,647,938,852]	5	hSpCas9	negative selection	6201546
136488456	136488479	X	+	27260156	CADOES1	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.004840574478314513	[550]	[393,525,572,565]	0	hSpCas9	negative selection	6201547
136492319	136492342	X	+	27260156	EWS502	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.0238272588400803	[1512]	[1442,1707,1552,1839]	0	hSpCas9	negative selection	6258512
136491984	136492007	X	-	27260156	EWS502	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.061334513346083475	[595]	[595,639,582,832]	1	hSpCas9	negative selection	6258513
136490463	136490486	X	+	27260156	EWS502	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.2536064326332038	[250]	[356,283,350,267]	4	hSpCas9	negative selection	6258514
136488527	136488550	X	+	27260156	EWS502	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.22849343347096446	[705]	[584,593,794,582]	-4	hSpCas9	negative selection	6322796
136490469	136490492	X	-	27260156	EWS502	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.25317792189458543	[742]	[982,864,877,1024]	4	hSpCas9	negative selection	6322797
136488456	136488479	X	+	27260156	EWS502	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.017294935415429286	[550]	[402,680,689,607]	0	hSpCas9	negative selection	6322798
136492319	136492342	X	+	27260156	EW8	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.26071234282083355	[1512]	[2618,1213,1106,1119]	5	hSpCas9	negative selection	6379763
136491984	136492007	X	-	27260156	EW8	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.049540968442396194	[595]	[518,645,417,431]	0	hSpCas9	negative selection	6379764
136490463	136490486	X	+	27260156	EW8	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.1846048166379919	[250]	[305,125,162,136]	-3	hSpCas9	negative selection	6379765
136488527	136488550	X	+	27260156	EW8	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.03027930615049701	[705]	[649,501,440,675]	0	hSpCas9	negative selection	6444047
136490469	136490492	X	-	27260156	EW8	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.11468897849263593	[742]	[670,487,467,622]	-2	hSpCas9	negative selection	6444048
136488456	136488479	X	+	27260156	EW8	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.08868325359196691	[550]	[623,540,314,461]	1	hSpCas9	negative selection	6444049
136492319	136492342	X	+	27260156	CORL105	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.2125203740293662	[1512]	[2113,1842,2162,2111]	4	hSpCas9	negative selection	6501014
136491984	136492007	X	-	27260156	CORL105	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.5780782781797278	[595]	[1238,952,1078,909]	9	hSpCas9	negative selection	6501015
136490463	136490486	X	+	27260156	CORL105	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.32563171317582296	[250]	[314,401,378,375]	6	hSpCas9	negative selection	6501016
136488527	136488550	X	+	27260156	CORL105	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.12437394984114725	[705]	[1019,854,896,835]	2	hSpCas9	negative selection	6565298
136490469	136490492	X	-	27260156	CORL105	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.10090826958822352	[742]	[899,919,926,981]	2	hSpCas9	negative selection	6565299
136488456	136488479	X	+	27260156	CORL105	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.0016627958542191346	[550]	[525,505,796,769]	0	hSpCas9	negative selection	6565300
136492319	136492342	X	+	27260156	HS294T	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.6399941585056976	[1512]	[746,825,909,1232]	8	hSpCas9	negative selection	6622265
136491984	136492007	X	-	27260156	HS294T	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.29451398152265057	[595]	[233,375,243,275]	4	hSpCas9	negative selection	6622266
136490463	136490486	X	+	27260156	HS294T	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.180987984631082	[250]	[53,93,110,85]	-3	hSpCas9	negative selection	6622267
136488527	136488550	X	+	27260156	HS294T	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.0023774581744626655	[705]	[248,222,285,351]	0	hSpCas9	negative selection	6686549
136490469	136490492	X	-	27260156	HS294T	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.33877350013572205	[742]	[375,283,402,395]	4	hSpCas9	negative selection	6686550
136488456	136488479	X	+	27260156	HS294T	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.20378982134975185	[550]	[244,185,189,384]	2	hSpCas9	negative selection	6686551
136492319	136492342	X	+	27260156	HCC44	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.2361143110258841	[1512]	[1998,1698,2811,1725]	4	hSpCas9	negative selection	6743516
136491984	136492007	X	-	27260156	HCC44	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.2377872979105186	[595]	[794,620,912,885]	4	hSpCas9	negative selection	6743517
136490463	136490486	X	+	27260156	HCC44	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.40683832568638856	[250]	[165,269,258,156]	-6	hSpCas9	negative selection	6743518
136488527	136488550	X	+	27260156	HCC44	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.1031128650898524	[705]	[818,737,560,822]	-2	hSpCas9	negative selection	6807800
136490469	136490492	X	-	27260156	HCC44	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.2718754518504475	[742]	[1042,747,1546,849]	4	hSpCas9	negative selection	6807801
136488456	136488479	X	+	27260156	HCC44	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.15144958134747735	[550]	[793,755,683,532]	2	hSpCas9	negative selection	6807802
136492319	136492342	X	+	27260156	G402	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.28834582094784356	[1512]	[2322,3088,1548,2113]	3	hSpCas9	negative selection	6864767
136491984	136492007	X	-	27260156	G402	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.2277504610097893	[595]	[938,899,652,922]	3	hSpCas9	negative selection	6864768
136490463	136490486	X	+	27260156	G402	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.6677443636035079	[250]	[137,231,163,228]	-7	hSpCas9	negative selection	6864769
136488527	136488550	X	+	27260156	G402	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.018457955949121918	[705]	[1091,893,856,685]	0	hSpCas9	negative selection	6929051
136490469	136490492	X	-	27260156	G402	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.13080745554743056	[742]	[1045,786,1210,921]	1	hSpCas9	negative selection	6929052
136488456	136488479	X	+	27260156	G402	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.2127611783163458	[550]	[771,1071,683,609]	2	hSpCas9	negative selection	6929053
136492319	136492342	X	+	27260156	L33	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.3664808777459001	[1512]	[2043,728,1134,2167]	7	hSpCas9	negative selection	6986018
136491984	136492007	X	-	27260156	L33	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.33560194705903074	[595]	[674,353,516,649]	7	hSpCas9	negative selection	6986019
136490463	136490486	X	+	27260156	L33	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.12544419722855094	[250]	[218,102,161,192]	-3	hSpCas9	negative selection	6986020
136488527	136488550	X	+	27260156	L33	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.25095602503292014	[705]	[659,220,419,504]	-5	hSpCas9	negative selection	7050302
136490469	136490492	X	-	27260156	L33	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.023943192080673192	[742]	[878,292,374,727]	0	hSpCas9	negative selection	7050303
136488456	136488479	X	+	27260156	L33	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.20074377940881652	[550]	[479,186,302,498]	-4	hSpCas9	negative selection	7050304
136492319	136492342	X	+	27260156	K562	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.3381805675084184	[1512]	[1713,1753,2002,1355]	4	hSpCas9	negative selection	7107269
136491984	136492007	X	-	27260156	K562	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.5539364573691392	[595]	[929,808,960,454]	7	hSpCas9	negative selection	7107270
136490463	136490486	X	+	27260156	K562	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.19600622255315303	[250]	[287,199,206,316]	2	hSpCas9	negative selection	7107271
136488527	136488550	X	+	27260156	K562	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.21122398552204208	[705]	[545,802,591,267]	-3	hSpCas9	negative selection	7171553
136490469	136490492	X	-	27260156	K562	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.027279502691890167	[742]	[647,443,998,500]	0	hSpCas9	negative selection	7171554
136488456	136488479	X	+	27260156	K562	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.07473236628300872	[550]	[876,404,291,327]	-1	hSpCas9	negative selection	7171555
136492319	136492342	X	+	27260156	HT29	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.07094225993866976	[1512]	[2035,2263,2019,1485]	1	hSpCas9	negative selection	7228520
136491984	136492007	X	-	27260156	HT29	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.23207923503674804	[595]	[1051,1031,685,679]	4	hSpCas9	negative selection	7228521
136490463	136490486	X	+	27260156	HT29	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.09163308609730214	[250]	[290,389,374,253]	1	hSpCas9	negative selection	7228522
136488527	136488550	X	+	27260156	HT29	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.1046052355672073	[705]	[896,908,724,686]	-2	hSpCas9	negative selection	7292804
136490469	136490492	X	-	27260156	HT29	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.11680785406896832	[742]	[1092,895,1078,858]	2	hSpCas9	negative selection	7292805
136488456	136488479	X	+	27260156	HT29	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.03889325898400661	[550]	[621,845,618,670]	0	hSpCas9	negative selection	7292806
136492319	136492342	X	+	27260156	MHHES1	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.40317008207561766	[1512]	[2627,2540,2320,1681]	7	hSpCas9	negative selection	7349771
136491984	136492007	X	-	27260156	MHHES1	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.252954296767904	[595]	[823,791,934,664]	4	hSpCas9	negative selection	7349772
136490463	136490486	X	+	27260156	MHHES1	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.028150996717254073	[250]	[236,357,240,270]	0	hSpCas9	negative selection	7349773
136488527	136488550	X	+	27260156	MHHES1	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.18286216479994533	[705]	[682,956,558,626]	-3	hSpCas9	negative selection	7414055
136490469	136490492	X	-	27260156	MHHES1	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.028914506448412536	[742]	[851,978,758,715]	0	hSpCas9	negative selection	7414056
136488456	136488479	X	+	27260156	MHHES1	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.05881605579095292	[550]	[776,711,710,441]	1	hSpCas9	negative selection	7414057
136492319	136492342	X	+	27260156	MEWO	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.07890091074899042	[1512]	[1959,1487,1126]	1	hSpCas9	negative selection	7471022
136491984	136492007	X	-	27260156	MEWO	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.25665351292131583	[595]	[712,749,543]	5	hSpCas9	negative selection	7471023
136490463	136490486	X	+	27260156	MEWO	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.3407338442391614	[250]	[188,171,195]	-6	hSpCas9	negative selection	7471024
136488527	136488550	X	+	27260156	MEWO	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.1899111391443955	[705]	[678,446,630]	-4	hSpCas9	negative selection	7535306
136490469	136490492	X	-	27260156	MEWO	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.07637476057977988	[742]	[899,721,608]	1	hSpCas9	negative selection	7535307
136488456	136488479	X	+	27260156	MEWO	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.28469297168434815	[550]	[539,437,313]	-6	hSpCas9	negative selection	7535308
136492319	136492342	X	+	27260156	LNCAPCLONEFGC	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.25673241640905986	[1512]	[1859,1334,2064,1367]	4	hSpCas9	negative selection	7592273
136491984	136492007	X	-	27260156	LNCAPCLONEFGC	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.3655007018792951	[595]	[673,712,681,709]	6	hSpCas9	negative selection	7592274
136490463	136490486	X	+	27260156	LNCAPCLONEFGC	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.21004175444417095	[250]	[314,244,208,274]	3	hSpCas9	negative selection	7592275
136488527	136488550	X	+	27260156	LNCAPCLONEFGC	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.18512519604857347	[705]	[703,436,533,575]	-3	hSpCas9	negative selection	7656557
136490469	136490492	X	-	27260156	LNCAPCLONEFGC	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.32592889492021215	[742]	[820,885,973,709]	5	hSpCas9	negative selection	7656558
136488456	136488479	X	+	27260156	LNCAPCLONEFGC	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.18920856849049142	[550]	[499,494,621,672]	3	hSpCas9	negative selection	7656559
136492319	136492342	X	+	27260156	PANC0327	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	-0.006314041606178433	[1512]	[1476,1098,1624,1193]	0	hSpCas9	negative selection	7713524
136491984	136492007	X	-	27260156	PANC0327	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.08340869556523478	[595]	[563,570,745,361]	1	hSpCas9	negative selection	7713525
136490463	136490486	X	+	27260156	PANC0327	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.3266631057234066	[250]	[144,296,255,406]	5	hSpCas9	negative selection	7713526
136488527	136488550	X	+	27260156	PANC0327	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.0033281295931487653	[705]	[777,485,700,579]	0	hSpCas9	negative selection	7777808
136490469	136490492	X	-	27260156	PANC0327	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.1054871765688774	[742]	[563,524,618,752]	-1	hSpCas9	negative selection	7777809
136488456	136488479	X	+	27260156	PANC0327	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.0644559848342876	[550]	[251,302,687,632]	-1	hSpCas9	negative selection	7777810
136492319	136492342	X	+	27260156	NCIH2009	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.7573819750019344	[1512]	[4036,3005,3772]	9	hSpCas9	negative selection	7834775
136491984	136492007	X	-	27260156	NCIH2009	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.6597482410928976	[595]	[1724,1273,1026]	8	hSpCas9	negative selection	7834776
136490463	136490486	X	+	27260156	NCIH2009	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.22511959009602833	[250]	[621,296,353]	3	hSpCas9	negative selection	7834777
136488527	136488550	X	+	27260156	NCIH2009	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.0264603104893405	[705]	[859,1095,923]	0	hSpCas9	negative selection	7899059
136490469	136490492	X	-	27260156	NCIH2009	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.4226794321690335	[742]	[1535,1424,1238]	6	hSpCas9	negative selection	7899060
136488456	136488479	X	+	27260156	NCIH2009	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.1799666674212835	[550]	[1180,811,683]	2	hSpCas9	negative selection	7899061
136492319	136492342	X	+	27260156	NCIH1373	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	1.2104719745645873	[1512]	[4259,4622,3760,775]	9	hSpCas9	negative selection	7956026
136491984	136492007	X	-	27260156	NCIH1373	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	1.0953645491551545	[595]	[1421,868,1939,400]	9	hSpCas9	negative selection	7956027
136490463	136490486	X	+	27260156	NCIH1373	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.8231291496181019	[250]	[246,97,73,63]	-7	hSpCas9	negative selection	7956028
136488527	136488550	X	+	27260156	NCIH1373	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.2108658890736289	[705]	[1059,725,1178,188]	2	hSpCas9	negative selection	8020310
136490469	136490492	X	-	27260156	NCIH1373	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.4979690353948134	[742]	[2215,838,935,234]	5	hSpCas9	negative selection	8020311
136488456	136488479	X	+	27260156	NCIH1373	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.5464890581722124	[550]	[975,741,834,286]	5	hSpCas9	negative selection	8020312
136492319	136492342	X	+	27260156	PATU8902	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.15248818500777062	[1512]	[2723,1711,2129,2897]	1	hSpCas9	negative selection	8077277
136491984	136492007	X	-	27260156	PATU8902	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	-0.30129003877346916	[595]	[524,807,626,752]	-3	hSpCas9	negative selection	8077278
136490463	136490486	X	+	27260156	PATU8902	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.49380727735009106	[250]	[381,666,526,366]	5	hSpCas9	negative selection	8077279
136488527	136488550	X	+	27260156	PATU8902	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.24860916142063993	[705]	[1192,1181,943,1433]	2	hSpCas9	negative selection	8141561
136490469	136490492	X	-	27260156	PATU8902	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.5333878888494472	[742]	[2204,1672,759,1526]	5	hSpCas9	negative selection	8141562
136488456	136488479	X	+	27260156	PATU8902	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.39236551970506495	[550]	[772,883,833,1654]	4	hSpCas9	negative selection	8141563
136492319	136492342	X	+	27260156	PANC1	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.003674397412144481	[1512]	[1143,1620,1398,1124]	0	hSpCas9	negative selection	8198528
136491984	136492007	X	-	27260156	PANC1	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.2292393507044574	[595]	[483,633,712,573]	3	hSpCas9	negative selection	8198529
136490463	136490486	X	+	27260156	PANC1	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.06532333629080378	[250]	[142,401,217,180]	1	hSpCas9	negative selection	8198530
136488527	136488550	X	+	27260156	PANC1	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.2001727286158827	[705]	[436,505,538,604]	-3	hSpCas9	negative selection	8262812
136490469	136490492	X	-	27260156	PANC1	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.07851073380849372	[742]	[599,911,543,676]	1	hSpCas9	negative selection	8262813
136488456	136488479	X	+	27260156	PANC1	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.4667095496483157	[550]	[532,936,633,574]	7	hSpCas9	negative selection	8262814
136492319	136492342	X	+	27260156	PANC0813	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.7802895610431468	[1512]	[3577,2554,3645,2507]	9	hSpCas9	negative selection	8319779
136491984	136492007	X	-	27260156	PANC0813	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.4884618951375537	[595]	[1272,934,814,932]	7	hSpCas9	negative selection	8319780
136490463	136490486	X	+	27260156	PANC0813	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.20057564619454082	[250]	[306,311,307,419]	3	hSpCas9	negative selection	8319781
136488527	136488550	X	+	27260156	PANC0813	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.25271611677079003	[705]	[623,845,646,660]	-4	hSpCas9	negative selection	8384063
136490469	136490492	X	-	27260156	PANC0813	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.17643934651740212	[742]	[1125,1140,924,775]	3	hSpCas9	negative selection	8384064
136488456	136488479	X	+	27260156	PANC0813	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.046254496932830874	[550]	[768,693,422,631]	0	hSpCas9	negative selection	8384065
136492319	136492342	X	+	27260156	RDES	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.14836523406770863	[1512]	[1503,1952,2023,2328]	2	hSpCas9	negative selection	8441030
136491984	136492007	X	-	27260156	RDES	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.24642549813052644	[595]	[625,753,887,1044]	4	hSpCas9	negative selection	8441031
136490463	136490486	X	+	27260156	RDES	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.03539968918927694	[250]	[230,314,261,322]	0	hSpCas9	negative selection	8441032
136488527	136488550	X	+	27260156	RDES	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.1878446030722113	[705]	[823,897,842,1161]	3	hSpCas9	negative selection	8505314
136490469	136490492	X	-	27260156	RDES	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.11746857299308866	[742]	[892,720,938,1192]	2	hSpCas9	negative selection	8505315
136488456	136488479	X	+	27260156	RDES	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.09970065242734324	[550]	[580,632,570,976]	1	hSpCas9	negative selection	8505316
136492319	136492342	X	+	27260156	PC3	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.1007706161337818	[1512]	[971,1403,2864,1869]	2	hSpCas9	negative selection	8562281
136491984	136492007	X	-	27260156	PC3	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.15036846669697485	[595]	[339,784,1031,704]	3	hSpCas9	negative selection	8562282
136490463	136490486	X	+	27260156	PC3	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.06894493900650178	[250]	[122,183,461,309]	-1	hSpCas9	negative selection	8562283
136488527	136488550	X	+	27260156	PC3	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.8034497306319337	[705]	[373,2821,1136,725]	9	hSpCas9	negative selection	8626565
136490469	136490492	X	-	27260156	PC3	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.026264987289045916	[742]	[602,632,1033,726]	0	hSpCas9	negative selection	8626566
136488456	136488479	X	+	27260156	PC3	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.06093747476952266	[550]	[303,565,1125,384]	-1	hSpCas9	negative selection	8626567
136492319	136492342	X	+	27260156	PATU8988T	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.27086102501762466	[1512]	[1722,1534,1985,1788]	4	hSpCas9	negative selection	8683532
136491984	136492007	X	-	27260156	PATU8988T	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.19379561089904568	[595]	[787,615,402,841]	3	hSpCas9	negative selection	8683533
136490463	136490486	X	+	27260156	PATU8988T	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.07320631099752073	[250]	[413,263,175,160]	1	hSpCas9	negative selection	8683534
136488527	136488550	X	+	27260156	PATU8988T	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.6470167313392201	[705]	[301,450,556,431]	-7	hSpCas9	negative selection	8747816
136490469	136490492	X	-	27260156	PATU8988T	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.09594525903739715	[742]	[702,818,469,714]	-2	hSpCas9	negative selection	8747817
136488456	136488479	X	+	27260156	PATU8988T	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.03033319764024875	[550]	[362,573,602,644]	0	hSpCas9	negative selection	8747818
136492319	136492342	X	+	27260156	T47D	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.04961952041496964	[1512]	[1826,1715,1941,1818]	1	hSpCas9	negative selection	8804783
136491984	136492007	X	-	27260156	T47D	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.26721967460737633	[595]	[931,783,769,862]	5	hSpCas9	negative selection	8804784
136490463	136490486	X	+	27260156	T47D	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.2011062055771522	[250]	[268,341,349,383]	4	hSpCas9	negative selection	8804785
136488527	136488550	X	+	27260156	T47D	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.23810557795844128	[705]	[667,558,676,903]	-5	hSpCas9	negative selection	8869067
136490469	136490492	X	-	27260156	T47D	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.17594014622659915	[742]	[941,983,1024,957]	4	hSpCas9	negative selection	8869068
136488456	136488479	X	+	27260156	T47D	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.0283375942764649	[550]	[605,509,725,791]	0	hSpCas9	negative selection	8869069
136492319	136492342	X	+	27260156	SU8686	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.5873197005697426	[1512]	[2018,2061,2100,2981]	8	hSpCas9	negative selection	8926034
136491984	136492007	X	-	27260156	SU8686	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.41169767555330433	[595]	[796,884,622,819]	7	hSpCas9	negative selection	8926035
136490463	136490486	X	+	27260156	SU8686	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.13732408416900554	[250]	[209,165,197,359]	-2	hSpCas9	negative selection	8926036
136488527	136488550	X	+	27260156	SU8686	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.004295597602611889	[705]	[583,586,639,1059]	0	hSpCas9	negative selection	8990318
136490469	136490492	X	-	27260156	SU8686	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.09335243286728256	[742]	[661,743,804,977]	1	hSpCas9	negative selection	8990319
136488456	136488479	X	+	27260156	SU8686	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.12460167231445304	[550]	[560,461,626,779]	2	hSpCas9	negative selection	8990320
136492319	136492342	X	+	27260156	SKES1	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.05814177214782257	[1512]	[1810,1622,1611,1294]	1	hSpCas9	negative selection	9047285
136491984	136492007	X	-	27260156	SKES1	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.27103695890937923	[595]	[859,823,687,543]	6	hSpCas9	negative selection	9047286
136490463	136490486	X	+	27260156	SKES1	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.23245375318668515	[250]	[296,238,339,290]	5	hSpCas9	negative selection	9047287
136488527	136488550	X	+	27260156	SKES1	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.23940676677072947	[705]	[555,532,684,591]	-5	hSpCas9	negative selection	9111569
136490469	136490492	X	-	27260156	SKES1	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.05482227047044819	[742]	[998,715,743,457]	-1	hSpCas9	negative selection	9111570
136488456	136488479	X	+	27260156	SKES1	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.1961195800190923	[550]	[451,547,512,412]	-4	hSpCas9	negative selection	9111571
136492319	136492342	X	+	27260156	TOV112D	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.3431736510070724	[1512]	[1956,1994,1659,2089]	6	hSpCas9	negative selection	9168536
136491984	136492007	X	-	27260156	TOV112D	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.36388694131541394	[595]	[719,1298,736,450]	7	hSpCas9	negative selection	9168537
136490463	136490486	X	+	27260156	TOV112D	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.013828834098228104	[250]	[229,306,213,256]	0	hSpCas9	negative selection	9168538
136488527	136488550	X	+	27260156	TOV112D	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.14581807407618463	[705]	[631,746,549,651]	-3	hSpCas9	negative selection	9232820
136490469	136490492	X	-	27260156	TOV112D	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.11479714968140053	[742]	[904,750,947,617]	2	hSpCas9	negative selection	9232821
136488456	136488479	X	+	27260156	TOV112D	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.1578159619003447	[550]	[547,655,429,390]	-3	hSpCas9	negative selection	9232822
136492319	136492342	X	+	27260156	TC71	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	-0.05068944782612195	[1512]	[1549,1518,1612,1580]	-1	hSpCas9	negative selection	9289787
136491984	136492007	X	-	27260156	TC71	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.21000176901171858	[595]	[680,754,718,806]	5	hSpCas9	negative selection	9289788
136490463	136490486	X	+	27260156	TC71	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.18745689443757518	[250]	[218,331,312,366]	5	hSpCas9	negative selection	9289789
136488527	136488550	X	+	27260156	TC71	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	-0.40441401502872754	[705]	[457,505,676,649]	-8	hSpCas9	negative selection	9354071
136490469	136490492	X	-	27260156	TC71	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	-0.001898407696316995	[742]	[753,815,684,939]	0	hSpCas9	negative selection	9354072
136488456	136488479	X	+	27260156	TC71	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	-0.07434394897710978	[550]	[540,724,499,474]	-2	hSpCas9	negative selection	9354073
136492319	136492342	X	+	27260156	TC32	viability	ATTAGTGTGACCTCGTTCACTGG	BRS3	ENSG00000102239	0.05245831929153444	[1512]	[1465,1114,1817,1613]	1	hSpCas9	negative selection	9411038
136491984	136492007	X	-	27260156	TC32	viability	CACCAACACCAATACCGTTCTGG	BRS3	ENSG00000102239	0.054804096805883606	[595]	[536,442,703,693]	1	hSpCas9	negative selection	9411039
136490463	136490486	X	+	27260156	TC32	viability	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	-0.029682013535047402	[250]	[265,185,258,214]	0	hSpCas9	negative selection	9411040
136488527	136488550	X	+	27260156	TC32	viability	TAACAATTCTCAGCGCTGACAGG	BRS3	ENSG00000102239	0.03146295815358413	[705]	[616,482,1005,706]	0	hSpCas9	negative selection	9475322
136490469	136490492	X	-	27260156	TC32	viability	TACATACCTGCTTACGGGCATGG	BRS3	ENSG00000102239	0.014729624573214695	[742]	[624,556,772,913]	0	hSpCas9	negative selection	9475323
136488456	136488479	X	+	27260156	TC32	viability	GTTCGGAAGAATTGGTTGTAAGG	BRS3	ENSG00000102239	0.049785356321016244	[550]	[581,403,683,508]	0	hSpCas9	negative selection	9475324
136488492	136488515	X	-	27869803	HPAFII	viability after 27 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.762914502293885	[298]	[120,68,NaN]	-5	hSpCas9	negative selection	9607703
136490152	136490175	X	-	27869803	HPAFII	viability after 27 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.46039239210397154	[372]	[181,342,NaN]	4	hSpCas9	negative selection	9607704
136490463	136490486	X	+	27869803	HPAFII	viability after 27 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.05752228782587776	[380]	[118,282,NaN]	0	hSpCas9	negative selection	9607705
136492153	136492176	X	-	27869803	HPAFII	viability after 27 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.23437611309877027	[832]	[374,369,NaN]	-2	hSpCas9	negative selection	9607706
136492249	136492272	X	+	27869803	HPAFII	viability after 27 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	0.6729243036099349	[358]	[169,409,NaN]	5	hSpCas9	negative selection	9607707
136492267	136492290	X	-	27869803	HPAFII	viability after 27 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	1.0223132613161288	[216]	[354,128,NaN]	8	hSpCas9	negative selection	9607708
136488492	136488515	X	-	27869803	HPAFII	viability after 15 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.30407959626496506	[298]	[353,201,NaN]	-3	hSpCas9	negative selection	9690152
136490152	136490175	X	-	27869803	HPAFII	viability after 15 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.49274860622399974	[372]	[523,588,NaN]	5	hSpCas9	negative selection	9690153
136490463	136490486	X	+	27869803	HPAFII	viability after 15 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.21748542754539335	[380]	[427,505,NaN]	2	hSpCas9	negative selection	9690154
136492153	136492176	X	-	27869803	HPAFII	viability after 15 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.4458970205159909	[832]	[774,583,NaN]	-5	hSpCas9	negative selection	9690155
136492249	136492272	X	+	27869803	HPAFII	viability after 15 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	0.4791931454028665	[358]	[506,556,NaN]	5	hSpCas9	negative selection	9690156
136492267	136492290	X	-	27869803	HPAFII	viability after 15 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.593377392005113	[216]	[571,214,NaN]	6	hSpCas9	negative selection	9690157
136488492	136488515	X	-	27869803	ASPC1	viability after 36 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	1.0154633373713424	[519]	[167,688,246]	8	hSpCas9	negative selection	9772601
136490152	136490175	X	-	27869803	ASPC1	viability after 36 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.8345971333438033	[764]	[417,954,131]	7	hSpCas9	negative selection	9772602
136490463	136490486	X	+	27869803	ASPC1	viability after 36 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.12667748051071237	[1186]	[327,552,454]	1	hSpCas9	negative selection	9772603
136492153	136492176	X	-	27869803	ASPC1	viability after 36 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	0.3293611665536518	[1788]	[588,1374,444]	3	hSpCas9	negative selection	9772604
136492249	136492272	X	+	27869803	ASPC1	viability after 36 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	0.572148756212718	[956]	[807,405,344]	6	hSpCas9	negative selection	9772605
136492267	136492290	X	-	27869803	ASPC1	viability after 36 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.8940913578090639	[606]	[862,314,122]	8	hSpCas9	negative selection	9772606
136488492	136488515	X	-	27869803	PATU8988S	viability after 35 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.03710864171433076	[421]	[228,101,NaN]	0	hSpCas9	negative selection	9855050
136490152	136490175	X	-	27869803	PATU8988S	viability after 35 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.11780325994527047	[747]	[336,217,NaN]	-1	hSpCas9	negative selection	9855051
136490463	136490486	X	+	27869803	PATU8988S	viability after 35 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.5998556302575049	[1080]	[806,511,NaN]	6	hSpCas9	negative selection	9855052
136492153	136492176	X	-	27869803	PATU8988S	viability after 35 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.6352996228449569	[1327]	[274,413,NaN]	-6	hSpCas9	negative selection	9855053
136492249	136492272	X	+	27869803	PATU8988S	viability after 35 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.04132657792184824	[980]	[357,409,NaN]	0	hSpCas9	negative selection	9855054
136492267	136492290	X	-	27869803	PATU8988S	viability after 35 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.4357601091818981	[643]	[276,424,NaN]	5	hSpCas9	negative selection	9855055
136488492	136488515	X	-	27869803	PATU8988S	viability after 31 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.39644965742939603	[421]	[257,174,NaN]	5	hSpCas9	negative selection	9937499
136490152	136490175	X	-	27869803	PATU8988S	viability after 31 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	-0.3202313254031225	[747]	[281,183,NaN]	-4	hSpCas9	negative selection	9937500
136490463	136490486	X	+	27869803	PATU8988S	viability after 31 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.2861527870516447	[1080]	[551,491,NaN]	3	hSpCas9	negative selection	9937501
136492153	136492176	X	-	27869803	PATU8988S	viability after 31 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.7622790446997192	[1327]	[276,356,NaN]	-7	hSpCas9	negative selection	9937502
136492249	136492272	X	+	27869803	PATU8988S	viability after 31 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	-0.09389687674154201	[980]	[362,370,NaN]	-1	hSpCas9	negative selection	9937503
136492267	136492290	X	-	27869803	PATU8988S	viability after 31 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	0.5346123857415519	[643]	[250,525,NaN]	6	hSpCas9	negative selection	9937504
136488492	136488515	X	-	27869803	HPAFII	viability after 35 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.30744137388915954	[298]	[47,205,NaN]	-2	hSpCas9	negative selection	10019948
136490152	136490175	X	-	27869803	HPAFII	viability after 35 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.504294574749573	[372]	[185,359,NaN]	3	hSpCas9	negative selection	10019949
136490463	136490486	X	+	27869803	HPAFII	viability after 35 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.09972283054603737	[380]	[42,390,NaN]	0	hSpCas9	negative selection	10019950
136492153	136492176	X	-	27869803	HPAFII	viability after 35 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.3707963466265656	[832]	[343,305,NaN]	-2	hSpCas9	negative selection	10019951
136492249	136492272	X	+	27869803	HPAFII	viability after 35 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	1.1725598586483765	[358]	[94,763,NaN]	7	hSpCas9	negative selection	10019952
136492267	136492290	X	-	27869803	HPAFII	viability after 35 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	1.696126583732767	[216]	[640,34,NaN]	9	hSpCas9	negative selection	10019953
136488492	136488515	X	-	27869803	HPAFII	viability after 31 days	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.5556628851976753	[298]	[61,170,NaN]	-4	hSpCas9	negative selection	10102397
136490152	136490175	X	-	27869803	HPAFII	viability after 31 days	TTGGAGGGCTGTCGCTCAAGTGG	BRS3	ENSG00000102239	0.8383080211764032	[372]	[279,476,NaN]	6	hSpCas9	negative selection	10102398
136490463	136490486	X	+	27869803	HPAFII	viability after 31 days	ACAAAGCCATGCCCGTAAGCAGG	BRS3	ENSG00000102239	0.47487561716095883	[380]	[99,511,NaN]	3	hSpCas9	negative selection	10102399
136492153	136492176	X	-	27869803	HPAFII	viability after 31 days	TCAGCCAGTAGAGAGCAAAGGGG	BRS3	ENSG00000102239	-0.47164639593967883	[832]	[272,406,NaN]	-3	hSpCas9	negative selection	10102400
136492249	136492272	X	+	27869803	HPAFII	viability after 31 days	TGACACCTCTCTTACCACCCTGG	BRS3	ENSG00000102239	1.0439629918778168	[358]	[167,684,NaN]	7	hSpCas9	negative selection	10102401
136492267	136492290	X	-	27869803	HPAFII	viability after 31 days	GGACCGTTCCCATCACAGCCAGG	BRS3	ENSG00000102239	1.3111798175082454	[216]	[529,53,NaN]	8	hSpCas9	negative selection	10102402
136488374	136488397	X	-	28162770	P31FUJ	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	-1.0807991109693287	[71]	[39]	-6	hSpCas9	negative selection	10119273
136488492	136488515	X	-	28162770	P31FUJ	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.7473753772441367	[129]	[90]	-5	hSpCas9	negative selection	10119274
136488427	136488450	X	+	28162770	P31FUJ	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	-0.13200156362688664	[151]	[162]	-1	hSpCas9	negative selection	10119275
136488402	136488425	X	+	28162770	P31FUJ	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	-0.02385531414288239	[153]	[177]	0	hSpCas9	negative selection	10119276
136488130	136488153	X	-	28162770	P31FUJ	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.4909448872187826	[306]	[506]	5	hSpCas9	negative selection	10119277
136488448	136488471	X	+	28162770	P31FUJ	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	-0.42073515500745384	[130]	[114]	-4	hSpCas9	negative selection	10119278
136490411	136490434	X	-	28162770	P31FUJ	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.706467448052436	[654]	[1255]	7	hSpCas9	negative selection	10119279
136490168	136490191	X	-	28162770	P31FUJ	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.2972431905363162	[472]	[682]	3	hSpCas9	negative selection	10119280
136490182	136490205	X	+	28162770	P31FUJ	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	-0.43855086963095474	[157]	[136]	-4	hSpCas9	negative selection	10119281
136488206	136488229	X	+	28162770	P31FUJ	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	0.6272675344411465	[118]	[215]	7	hSpCas9	negative selection	10119282
136488374	136488397	X	-	28162770	TF1	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	NaN	[NaN]	[189]	1	hSpCas9	negative selection	10288639
136488492	136488515	X	-	28162770	TF1	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	NaN	[NaN]	[99]	1	hSpCas9	negative selection	10288640
136488427	136488450	X	+	28162770	TF1	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	NaN	[NaN]	[258]	1	hSpCas9	negative selection	10288641
136488402	136488425	X	+	28162770	TF1	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10288642
136488130	136488153	X	-	28162770	TF1	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	NaN	[NaN]	[359]	1	hSpCas9	negative selection	10288643
136488448	136488471	X	+	28162770	TF1	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	NaN	[NaN]	[102]	1	hSpCas9	negative selection	10288644
136490411	136490434	X	-	28162770	TF1	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	NaN	[NaN]	[763]	1	hSpCas9	negative selection	10288645
136490168	136490191	X	-	28162770	TF1	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	NaN	[NaN]	[430]	1	hSpCas9	negative selection	10288646
136490182	136490205	X	+	28162770	TF1	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10288647
136488206	136488229	X	+	28162770	TF1	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	NaN	[NaN]	[281]	1	hSpCas9	negative selection	10288648
136488374	136488397	X	-	28162770	SKM1	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	0.8478497002856638	[21]	[69]	7	hSpCas9	negative selection	10458005
136488492	136488515	X	-	28162770	SKM1	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.3931583992181311	[25]	[34]	-3	hSpCas9	negative selection	10458006
136488427	136488450	X	+	28162770	SKM1	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.8718951742523149	[33]	[109]	8	hSpCas9	negative selection	10458007
136488402	136488425	X	+	28162770	SKM1	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	-0.2718046154615259	[55]	[81]	-2	hSpCas9	negative selection	10458008
136488130	136488153	X	-	28162770	SKM1	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	1.14019626926561	[86]	[338]	9	hSpCas9	negative selection	10458009
136488448	136488471	X	+	28162770	SKM1	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.29664279847661346	[34]	[75]	3	hSpCas9	negative selection	10458010
136490411	136490434	X	-	28162770	SKM1	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.4436822862257379	[135]	[326]	4	hSpCas9	negative selection	10458011
136490168	136490191	X	-	28162770	SKM1	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	-0.2040887754995626	[100]	[154]	-2	hSpCas9	negative selection	10458012
136490182	136490205	X	+	28162770	SKM1	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	-0.02131050624541242	[30]	[53]	0	hSpCas9	negative selection	10458013
136488206	136488229	X	+	28162770	SKM1	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	0.20774564537204668	[47]	[97]	2	hSpCas9	negative selection	10458014
136488374	136488397	X	-	28162770	SKM1	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	0.8478497002856638	[21]	[69]	7	hSpCas9	negative selection	10627371
136488492	136488515	X	-	28162770	SKM1	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.3931583992181311	[25]	[34]	-3	hSpCas9	negative selection	10627372
136488427	136488450	X	+	28162770	SKM1	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.8718951742523149	[33]	[109]	8	hSpCas9	negative selection	10627373
136488402	136488425	X	+	28162770	SKM1	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	-0.2718046154615259	[55]	[81]	-2	hSpCas9	negative selection	10627374
136488130	136488153	X	-	28162770	SKM1	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	1.14019626926561	[86]	[338]	9	hSpCas9	negative selection	10627375
136488448	136488471	X	+	28162770	SKM1	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.29664279847661346	[34]	[75]	3	hSpCas9	negative selection	10627376
136490411	136490434	X	-	28162770	SKM1	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.4436822862257379	[135]	[326]	4	hSpCas9	negative selection	10627377
136490168	136490191	X	-	28162770	SKM1	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	-0.2040887754995626	[100]	[154]	-2	hSpCas9	negative selection	10627378
136490182	136490205	X	+	28162770	SKM1	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	-0.02131050624541242	[30]	[53]	0	hSpCas9	negative selection	10627379
136488206	136488229	X	+	28162770	SKM1	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	0.20774564537204668	[47]	[97]	2	hSpCas9	negative selection	10627380
136488374	136488397	X	-	28162770	PL21	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	1.5104797351014707	[74]	[92]	9	hSpCas9	negative selection	10796737
136488492	136488515	X	-	28162770	PL21	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.21741760592115567	[82]	[41]	2	hSpCas9	negative selection	10796738
136488427	136488450	X	+	28162770	PL21	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	-0.5763543438635234	[184]	[53]	-4	hSpCas9	negative selection	10796739
136488402	136488425	X	+	28162770	PL21	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	0.7576213787883692	[158]	[116]	6	hSpCas9	negative selection	10796740
136488130	136488153	X	-	28162770	PL21	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.9535735195112899	[330]	[278]	7	hSpCas9	negative selection	10796741
136488448	136488471	X	+	28162770	PL21	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	-0.32181308870603553	[111]	[38]	-2	hSpCas9	negative selection	10796742
136490411	136490434	X	-	28162770	PL21	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	1.2516699151294022	[439]	[455]	8	hSpCas9	negative selection	10796743
136490168	136490191	X	-	28162770	PL21	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.9705222085787257	[366]	[312]	7	hSpCas9	negative selection	10796744
136490182	136490205	X	+	28162770	PL21	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	0.7660437793947917	[126]	[93]	6	hSpCas9	negative selection	10796745
136488206	136488229	X	+	28162770	PL21	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	-0.7294710576192818	[79]	[20]	-5	hSpCas9	negative selection	10796746
136488374	136488397	X	-	28162770	P31FUJ	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	-1.0807991109693287	[71]	[39]	-6	hSpCas9	negative selection	10966103
136488492	136488515	X	-	28162770	P31FUJ	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.7473753772441367	[129]	[90]	-5	hSpCas9	negative selection	10966104
136488427	136488450	X	+	28162770	P31FUJ	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	-0.13200156362688664	[151]	[162]	-1	hSpCas9	negative selection	10966105
136488402	136488425	X	+	28162770	P31FUJ	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	-0.02385531414288239	[153]	[177]	0	hSpCas9	negative selection	10966106
136488130	136488153	X	-	28162770	P31FUJ	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.4909448872187826	[306]	[506]	5	hSpCas9	negative selection	10966107
136488448	136488471	X	+	28162770	P31FUJ	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	-0.42073515500745384	[130]	[114]	-4	hSpCas9	negative selection	10966108
136490411	136490434	X	-	28162770	P31FUJ	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.706467448052436	[654]	[1255]	7	hSpCas9	negative selection	10966109
136490168	136490191	X	-	28162770	P31FUJ	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.2972431905363162	[472]	[682]	3	hSpCas9	negative selection	10966110
136490182	136490205	X	+	28162770	P31FUJ	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	-0.43855086963095474	[157]	[136]	-4	hSpCas9	negative selection	10966111
136488206	136488229	X	+	28162770	P31FUJ	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	0.6272675344411465	[118]	[215]	7	hSpCas9	negative selection	10966112
136488374	136488397	X	-	28162770	OCIAML5	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	0.03245621171606694	[38]	[71]	0	hSpCas9	negative selection	11135469
136488492	136488515	X	-	28162770	OCIAML5	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.4661754172446697	[74]	[97]	-3	hSpCas9	negative selection	11135470
136488427	136488450	X	+	28162770	OCIAML5	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	-0.7470970112624546	[105]	[113]	-5	hSpCas9	negative selection	11135471
136488402	136488425	X	+	28162770	OCIAML5	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	0.9035951170121143	[68]	[232]	7	hSpCas9	negative selection	11135472
136488130	136488153	X	-	28162770	OCIAML5	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.5402508519147633	[215]	[566]	5	hSpCas9	negative selection	11135473
136488448	136488471	X	+	28162770	OCIAML5	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.27346431121986203	[54]	[119]	2	hSpCas9	negative selection	11135474
136490411	136490434	X	-	28162770	OCIAML5	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	1.331399434266589	[270]	[1230]	9	hSpCas9	negative selection	11135475
136490168	136490191	X	-	28162770	OCIAML5	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	1.1384523761251177	[228]	[909]	8	hSpCas9	negative selection	11135476
136490182	136490205	X	+	28162770	OCIAML5	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	1.2372007672330905	[46]	[199]	9	hSpCas9	negative selection	11135477
136488206	136488229	X	+	28162770	OCIAML5	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	-0.09717906870052856	[95]	[161]	0	hSpCas9	negative selection	11135478
136488374	136488397	X	-	28162770	EOL1	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	0.3289380266498697	[135]	[89]	3	hSpCas9	negative selection	11304835
136488492	136488515	X	-	28162770	EOL1	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	1.3261647550870568	[80]	[106]	9	hSpCas9	negative selection	11304836
136488427	136488450	X	+	28162770	EOL1	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	-0.2556822382635163	[280]	[123]	-2	hSpCas9	negative selection	11304837
136488402	136488425	X	+	28162770	EOL1	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	-0.23493044243666214	[343]	[153]	-2	hSpCas9	negative selection	11304838
136488130	136488153	X	-	28162770	EOL1	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.32957148222135924	[505]	[334]	3	hSpCas9	negative selection	11304839
136488448	136488471	X	+	28162770	EOL1	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.08501244376378064	[271]	[151]	0	hSpCas9	negative selection	11304840
136490411	136490434	X	-	28162770	EOL1	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.32834051368175565	[643]	[425]	3	hSpCas9	negative selection	11304841
136490168	136490191	X	-	28162770	EOL1	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	1.1133812355629111	[378]	[431]	8	hSpCas9	negative selection	11304842
136490182	136490205	X	+	28162770	EOL1	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	0.7634853388380185	[141]	[126]	6	hSpCas9	negative selection	11304843
136488206	136488229	X	+	28162770	EOL1	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	-0.5914673754331303	[142]	[49]	-4	hSpCas9	negative selection	11304844
136488374	136488397	X	-	28162770	MOLM13	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	-0.020048664781712855	[114]	[81]	0	hSpCas9	negative selection	11474201
136488492	136488515	X	-	28162770	MOLM13	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.0771067118589327	[177]	[121]	0	hSpCas9	negative selection	11474202
136488427	136488450	X	+	28162770	MOLM13	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.5432546438792237	[316]	[333]	4	hSpCas9	negative selection	11474203
136488402	136488425	X	+	28162770	MOLM13	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	0.7960494301434557	[230]	[289]	6	hSpCas9	negative selection	11474204
136488130	136488153	X	-	28162770	MOLM13	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	1.2062515828294247	[412]	[688]	8	hSpCas9	negative selection	11474205
136488448	136488471	X	+	28162770	MOLM13	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	1.1906235898701254	[162]	[268]	8	hSpCas9	negative selection	11474206
136490411	136490434	X	-	28162770	MOLM13	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.6915981305643979	[625]	[730]	5	hSpCas9	negative selection	11474207
136490168	136490191	X	-	28162770	MOLM13	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.9053942209493531	[445]	[603]	7	hSpCas9	negative selection	11474208
136490182	136490205	X	+	28162770	MOLM13	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	0.5099534411111227	[168]	[173]	4	hSpCas9	negative selection	11474209
136488206	136488229	X	+	28162770	MOLM13	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	-0.6266282172397111	[204]	[95]	-4	hSpCas9	negative selection	11474210
136488374	136488397	X	-	28162770	HEL	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	0.6427388320003568	[86]	[86]	5	hSpCas9	negative selection	11643567
136488492	136488515	X	-	28162770	HEL	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.8170690125626705	[108]	[122]	7	hSpCas9	negative selection	11643568
136488427	136488450	X	+	28162770	HEL	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.49372888286729033	[213]	[192]	4	hSpCas9	negative selection	11643569
136488402	136488425	X	+	28162770	HEL	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	0.23372512034928317	[238]	[179]	2	hSpCas9	negative selection	11643570
136488130	136488153	X	-	28162770	HEL	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	1.2387143254439308	[347]	[525]	9	hSpCas9	negative selection	11643571
136488448	136488471	X	+	28162770	HEL	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.0466357736740004	[129]	[85]	0	hSpCas9	negative selection	11643572
136490411	136490434	X	-	28162770	HEL	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.7707722212873862	[527]	[576]	6	hSpCas9	negative selection	11643573
136490168	136490191	X	-	28162770	HEL	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.5292497761877594	[422]	[390]	4	hSpCas9	negative selection	11643574
136490182	136490205	X	+	28162770	HEL	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	0.5557555304057169	[187]	[176]	5	hSpCas9	negative selection	11643575
136488206	136488229	X	+	28162770	HEL	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	0.27449554420045413	[181]	[140]	2	hSpCas9	negative selection	11643576
136488374	136488397	X	-	28162770	MV411	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	2.0023250529462437	[47]	[161]	9	hSpCas9	negative selection	11812933
136488492	136488515	X	-	28162770	MV411	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	1.341764933330928	[36]	[78]	9	hSpCas9	negative selection	11812934
136488427	136488450	X	+	28162770	MV411	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.6871371042958881	[173]	[235]	6	hSpCas9	negative selection	11812935
136488402	136488425	X	+	28162770	MV411	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	0.6569155247197186	[194]	[258]	6	hSpCas9	negative selection	11812936
136488130	136488153	X	-	28162770	MV411	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.913767602355921	[292]	[464]	7	hSpCas9	negative selection	11812937
136488448	136488471	X	+	28162770	MV411	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.24743755078277513	[111]	[111]	2	hSpCas9	negative selection	11812938
136490411	136490434	X	-	28162770	MV411	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.5351707257865408	[443]	[541]	5	hSpCas9	negative selection	11812939
136490168	136490191	X	-	28162770	MV411	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.47305675727314345	[318]	[372]	4	hSpCas9	negative selection	11812940
136490182	136490205	X	+	28162770	MV411	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	0.42800979642459624	[74]	[84]	4	hSpCas9	negative selection	11812941
136488206	136488229	X	+	28162770	MV411	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	1.0215561433664475	[68]	[117]	8	hSpCas9	negative selection	11812942
136488374	136488397	X	-	28162770	MONOMAC1	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	-0.734693633002353	[44]	[30]	-6	hSpCas9	negative selection	11982299
136488492	136488515	X	-	28162770	MONOMAC1	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	-0.46833886887694787	[34]	[28]	-4	hSpCas9	negative selection	11982300
136488427	136488450	X	+	28162770	MONOMAC1	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	-0.002658801892702428	[103]	[118]	0	hSpCas9	negative selection	11982301
136488402	136488425	X	+	28162770	MONOMAC1	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	1.1219135480279132	[96]	[241]	8	hSpCas9	negative selection	11982302
136488130	136488153	X	-	28162770	MONOMAC1	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.43698647211248876	[211]	[328]	4	hSpCas9	negative selection	11982303
136488448	136488471	X	+	28162770	MONOMAC1	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	1.0977064185015784	[74]	[183]	8	hSpCas9	negative selection	11982304
136490411	136490434	X	-	28162770	MONOMAC1	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.7628857135651113	[291]	[567]	7	hSpCas9	negative selection	11982305
136490168	136490191	X	-	28162770	MONOMAC1	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.5254291774115373	[219]	[362]	5	hSpCas9	negative selection	11982306
136490182	136490205	X	+	28162770	MONOMAC1	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	0.5619550534366515	[64]	[109]	5	hSpCas9	negative selection	11982307
136488206	136488229	X	+	28162770	MONOMAC1	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	-0.11641838685126887	[86]	[91]	-1	hSpCas9	negative selection	11982308
136488374	136488397	X	-	28162770	OCIAML2	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	1.662395593388622	[10]	[192]	9	hSpCas9	negative selection	12151665
136488492	136488515	X	-	28162770	OCIAML2	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.5443205162238103	[11]	[96]	5	hSpCas9	negative selection	12151666
136488427	136488450	X	+	28162770	OCIAML2	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.3046638875831442	[25]	[177]	3	hSpCas9	negative selection	12151667
136488402	136488425	X	+	28162770	OCIAML2	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	-0.0966549825852035	[48]	[253]	-1	hSpCas9	negative selection	12151668
136488130	136488153	X	-	28162770	OCIAML2	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.8301040473760779	[47]	[472]	7	hSpCas9	negative selection	12151669
136488448	136488471	X	+	28162770	OCIAML2	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	0.43626077036635735	[31]	[239]	4	hSpCas9	negative selection	12151670
136490411	136490434	X	-	28162770	OCIAML2	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	0.5813222543925607	[74]	[621]	5	hSpCas9	negative selection	12151671
136490168	136490191	X	-	28162770	OCIAML2	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.5128820519692698	[54]	[434]	5	hSpCas9	negative selection	12151672
136490182	136490205	X	+	28162770	OCIAML2	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	0.7664093720586881	[20]	[197]	7	hSpCas9	negative selection	12151673
136488206	136488229	X	+	28162770	OCIAML2	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	-0.3153515997642502	[21]	[97]	-3	hSpCas9	negative selection	12151674
136488374	136488397	X	-	28162770	OCIAML3	viability	AAGATCTCCAAAAGCCAGGCTGG	BRS3	ENSG00000102239	0.8654239783131341	[17]	[98]	7	hSpCas9	negative selection	12321031
136488492	136488515	X	-	28162770	OCIAML3	viability	ACACACCAACAGAAGTGAGCCGG	BRS3	ENSG00000102239	0.11871040759536577	[17]	[58]	1	hSpCas9	negative selection	12321032
136488427	136488450	X	+	28162770	OCIAML3	viability	GCAACTCACTACCTTGCAGAAGG	BRS3	ENSG00000102239	0.7279204545631992	[50]	[254]	6	hSpCas9	negative selection	12321033
136488402	136488425	X	+	28162770	OCIAML3	viability	TCTGCTAACTTGTGTGCCAGTGG	BRS3	ENSG00000102239	1.1735462736754658	[41]	[285]	8	hSpCas9	negative selection	12321034
136488130	136488153	X	-	28162770	OCIAML3	viability	AAAGTCTGATTAGGTGAGTGAGG	BRS3	ENSG00000102239	0.572707804642259	[99]	[448]	5	hSpCas9	negative selection	12321035
136488448	136488471	X	+	28162770	OCIAML3	viability	GGATGGCTGTTCGGAAGAATTGG	BRS3	ENSG00000102239	-0.35696844302331393	[41]	[98]	-3	hSpCas9	negative selection	12321036
136490411	136490434	X	-	28162770	OCIAML3	viability	GTAAAGGGTCCTAGCAATCAAGG	BRS3	ENSG00000102239	-0.03601218720327637	[143]	[423]	0	hSpCas9	negative selection	12321037
136490168	136490191	X	-	28162770	OCIAML3	viability	AGTCTTCAGGATGGCATTGGAGG	BRS3	ENSG00000102239	0.47447209755860337	[71]	[301]	4	hSpCas9	negative selection	12321038
136490182	136490205	X	+	28162770	OCIAML3	viability	CTGAAGACTTGTGTAAAAGCTGG	BRS3	ENSG00000102239	0.3887143682440013	[41]	[165]	3	hSpCas9	negative selection	12321039
136488206	136488229	X	+	28162770	OCIAML3	viability	ACACAAATAAAGGATGGAGCGGG	BRS3	ENSG00000102239	0.34145210748112625	[39]	[152]	3	hSpCas9	negative selection	12321040