Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:84446
• Symbol:BRSK1
• Description:BR serine/threonine kinase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/BRSK1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
55287230	55287253	19	-	26472758	Jiyoye	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	1.3820844005430428	[57]	[113]	8	hSpCas9	negative selection	16271
55306335	55306358	19	+	26472758	Jiyoye	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	-1.3330653446931935	[146]	[43]	-7	hSpCas9	negative selection	16272
55289534	55289557	19	+	26472758	Jiyoye	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-0.38290154911989516	[165]	[95]	-3	hSpCas9	negative selection	16273
55289573	55289596	19	-	26472758	Jiyoye	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	1.221619728349797	[57]	[101]	7	hSpCas9	negative selection	16274
55304070	55304093	19	-	26472758	Jiyoye	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	0.21135605576833383	[259]	[226]	1	hSpCas9	negative selection	16275
55304584	55304607	19	+	26472758	Jiyoye	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	-0.3345126229027361	[101]	[60]	-2	hSpCas9	negative selection	16276
55304685	55304708	19	-	26472758	Jiyoye	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-0.7651401673614329	[150]	[66]	-5	hSpCas9	negative selection	16277
55304843	55304866	19	-	26472758	Jiyoye	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	-0.37601322942097826	[295]	[171]	-3	hSpCas9	negative selection	16278
55306297	55306320	19	+	26472758	Jiyoye	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	-0.43891193504044523	[150]	[83]	-3	hSpCas9	negative selection	16279
55306322	55306345	19	-	26472758	Jiyoye	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.75509868492618	[65]	[83]	5	hSpCas9	negative selection	16280
55287230	55287253	19	-	26472758	KBM7	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.6597779926613646	[714,569]	[736,238]	7	hSpCas9	negative selection	207389
55306335	55306358	19	+	26472758	KBM7	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	-0.09426302439260081	[360,228]	[106,145]	-1	hSpCas9	negative selection	207390
55289534	55289557	19	+	26472758	KBM7	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-1.0061270612490558	[500,503]	[141,96]	-6	hSpCas9	negative selection	207391
55289573	55289596	19	-	26472758	KBM7	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	0.7702103508182938	[328,235]	[160,279]	8	hSpCas9	negative selection	207392
55304070	55304093	19	-	26472758	KBM7	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	0.0028631085332571082	[885,797]	[575,235]	0	hSpCas9	negative selection	207393
55304584	55304607	19	+	26472758	KBM7	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	0.36603969731239716	[290,261]	[252,90]	4	hSpCas9	negative selection	207394
55304685	55304708	19	-	26472758	KBM7	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-0.3552276162839313	[461,328]	[75,203]	-3	hSpCas9	negative selection	207395
55304843	55304866	19	-	26472758	KBM7	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	0.4007605686312911	[634,392]	[351,277]	4	hSpCas9	negative selection	207396
55306297	55306320	19	+	26472758	KBM7	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	0.29229716214802315	[515,545]	[305,309]	3	hSpCas9	negative selection	207397
55306322	55306345	19	-	26472758	KBM7	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.8048249759047846	[452,292]	[203,387]	8	hSpCas9	negative selection	207398
55287230	55287253	19	-	26472758	Raji	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.26036439574247977	[294]	[81]	2	hSpCas9	negative selection	398507
55306335	55306358	19	+	26472758	Raji	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	-1.1531440148496195	[229]	[23]	-7	hSpCas9	negative selection	398508
55289534	55289557	19	+	26472758	Raji	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	0.8093021824406049	[149]	[60]	7	hSpCas9	negative selection	398509
55289573	55289596	19	-	26472758	Raji	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.5320267493699331	[161]	[25]	-4	hSpCas9	negative selection	398510
55304070	55304093	19	-	26472758	Raji	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	0.26608128139265774	[386]	[107]	2	hSpCas9	negative selection	398511
55304584	55304607	19	+	26472758	Raji	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	-0.19842489415048603	[88]	[17]	-2	hSpCas9	negative selection	398512
55304685	55304708	19	-	26472758	Raji	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-0.22030382880244775	[250]	[49]	-2	hSpCas9	negative selection	398513
55304843	55304866	19	-	26472758	Raji	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	-0.3361065393946763	[494]	[90]	-3	hSpCas9	negative selection	398514
55306297	55306320	19	+	26472758	Raji	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	0.4614920360101116	[265]	[84]	4	hSpCas9	negative selection	398515
55306322	55306345	19	-	26472758	Raji	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.4926736912583913	[244]	[79]	5	hSpCas9	negative selection	398516
55287230	55287253	19	-	26472758	K562	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.8930759037049927	[575]	[902]	7	hSpCas9	negative selection	589625
55306335	55306358	19	+	26472758	K562	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	0.9351758924101998	[183]	[296]	7	hSpCas9	negative selection	589626
55289534	55289557	19	+	26472758	K562	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-0.6961274221233109	[308]	[160]	-4	hSpCas9	negative selection	589627
55289573	55289596	19	-	26472758	K562	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.28788482378214586	[268]	[185]	-2	hSpCas9	negative selection	589628
55304070	55304093	19	-	26472758	K562	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.664867708582726	[677]	[360]	-4	hSpCas9	negative selection	589629
55304584	55304607	19	+	26472758	K562	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	0.7093047763958522	[191]	[264]	6	hSpCas9	negative selection	589630
55304685	55304708	19	-	26472758	K562	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-2.6540102891938755	[424]	[56]	-8	hSpCas9	negative selection	589631
55304843	55304866	19	-	26472758	K562	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	1.2193789815009615	[493]	[970]	8	hSpCas9	negative selection	589632
55306297	55306320	19	+	26472758	K562	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	0.2380911076944356	[456]	[454]	1	hSpCas9	negative selection	589633
55306322	55306345	19	-	26472758	K562	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	-0.19615386371953453	[360]	[265]	-1	hSpCas9	negative selection	589634
55287026	55287049	19	+	26627737	DLD1	viability	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	-0.26631101783530986	[985]	[266,254,247]	-3	hSpCas9	negative selection	806865
55289483	55289506	19	-	26627737	DLD1	viability	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.3747388351418739	[1236]	[355,630,519]	4	hSpCas9	negative selection	806866
55294113	55294136	19	-	26627737	DLD1	viability	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.6007909492281684	[267]	[171,102,107]	6	hSpCas9	negative selection	806867
55294379	55294402	19	-	26627737	DLD1	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.16651433448615177	[518]	[133,246,169]	1	hSpCas9	negative selection	806868
55301586	55301609	19	-	26627737	DLD1	viability	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.5632314928074307	[321]	[194,169,90]	5	hSpCas9	negative selection	806869
55302118	55302141	19	+	26627737	DLD1	viability	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-1.3241432850883244	[1992]	[208,311,230]	-8	hSpCas9	negative selection	806870
55287026	55287049	19	+	26627737	GBM cells	viability after 5 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	-0.24834421638998283	[370]	[179,154]	-4	hSpCas9	negative selection	889180
55289483	55289506	19	-	26627737	GBM cells	viability after 5 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.2647516681043047	[685]	[469,413]	4	hSpCas9	negative selection	889181
55294113	55294136	19	-	26627737	GBM cells	viability after 5 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.9562470499516372	[73]	[86,66]	9	hSpCas9	negative selection	889182
55294379	55294402	19	-	26627737	GBM cells	viability after 5 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.2601526110819333	[363]	[163,161]	-4	hSpCas9	negative selection	889183
55301586	55301609	19	-	26627737	GBM cells	viability after 5 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.020543319287216644	[215]	[105,128]	0	hSpCas9	negative selection	889184
55302118	55302141	19	+	26627737	GBM cells	viability after 5 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.755090270265122	[641]	[201,205]	-8	hSpCas9	negative selection	889185
55287026	55287049	19	+	26627737	GBM cells	viability after 13 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	-0.0749105723803507	[370]	[205,178]	-1	hSpCas9	negative selection	971495
55289483	55289506	19	-	26627737	GBM cells	viability after 13 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.3814199036414583	[685]	[598,391]	5	hSpCas9	negative selection	971496
55294113	55294136	19	-	26627737	GBM cells	viability after 13 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	-0.830320286324967	[73]	[10,31]	-7	hSpCas9	negative selection	971497
55294379	55294402	19	-	26627737	GBM cells	viability after 13 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.6029157592823071	[363]	[134,125]	-6	hSpCas9	negative selection	971498
55301586	55301609	19	-	26627737	GBM cells	viability after 13 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.6390237379245876	[215]	[109,46]	-6	hSpCas9	negative selection	971499
55302118	55302141	19	+	26627737	GBM cells	viability after 13 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-1.2173475747572569	[641]	[183,121]	-8	hSpCas9	negative selection	971500
55287026	55287049	19	+	26627737	GBM cells	viability after 21 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.9294611594932964	[370]	[374,391]	8	hSpCas9	negative selection	1053810
55289483	55289506	19	-	26627737	GBM cells	viability after 21 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.18631580901757894	[685]	[445,403]	2	hSpCas9	negative selection	1053811
55294113	55294136	19	-	26627737	GBM cells	viability after 21 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.678523619146788	[73]	[67,60]	7	hSpCas9	negative selection	1053812
55294379	55294402	19	-	26627737	GBM cells	viability after 21 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.29783973597580515	[363]	[163,157]	-3	hSpCas9	negative selection	1053813
55301586	55301609	19	-	26627737	GBM cells	viability after 21 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.14165886672115025	[215]	[106,149]	1	hSpCas9	negative selection	1053814
55302118	55302141	19	+	26627737	GBM cells	viability after 21 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-1.7459106116853629	[641]	[115,92]	-8	hSpCas9	negative selection	1053815
55287026	55287049	19	+	26627737	RPE1	viability after 9 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.5214162952221846	[1011]	[552,327]	3	hSpCas9	negative selection	1136125
55289483	55289506	19	-	26627737	RPE1	viability after 9 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.35247637280307664	[2252]	[862,948]	2	hSpCas9	negative selection	1136126
55294113	55294136	19	-	26627737	RPE1	viability after 9 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.3994686038911051	[491]	[193,214]	2	hSpCas9	negative selection	1136127
55294379	55294402	19	-	26627737	RPE1	viability after 9 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.7714461254763847	[783]	[342,516]	5	hSpCas9	negative selection	1136128
55301586	55301609	19	-	26627737	RPE1	viability after 9 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.16065797968730455	[811]	[188,276]	-1	hSpCas9	negative selection	1136129
55302118	55302141	19	+	26627737	RPE1	viability after 9 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.7044885224713798	[2307]	[397,501]	-5	hSpCas9	negative selection	1136130
55287026	55287049	19	+	26627737	RPE1	viability after 12 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.5382004197060579	[1011]	[507,274]	3	hSpCas9	negative selection	1218440
55289483	55289506	19	-	26627737	RPE1	viability after 12 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.22194580045902335	[2252]	[721,688]	1	hSpCas9	negative selection	1218441
55294113	55294136	19	-	26627737	RPE1	viability after 12 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.6268302545101545	[491]	[241,163]	4	hSpCas9	negative selection	1218442
55294379	55294402	19	-	26627737	RPE1	viability after 12 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.9261849061644495	[783]	[425,372]	6	hSpCas9	negative selection	1218443
55301586	55301609	19	-	26627737	RPE1	viability after 12 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.24343993585861412	[811]	[266,248]	1	hSpCas9	negative selection	1218444
55302118	55302141	19	+	26627737	RPE1	viability after 12 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.6486258877518635	[2307]	[481,303]	-4	hSpCas9	negative selection	1218445
55287026	55287049	19	+	26627737	RPE1	viability after 15 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.4548300551128163	[1011]	[483,303]	3	hSpCas9	negative selection	1300755
55289483	55289506	19	-	26627737	RPE1	viability after 15 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.45638332706451723	[2252]	[622,1116]	3	hSpCas9	negative selection	1300756
55294113	55294136	19	-	26627737	RPE1	viability after 15 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	1.0294411353604618	[491]	[278,288]	6	hSpCas9	negative selection	1300757
55294379	55294402	19	-	26627737	RPE1	viability after 15 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.5575782764344464	[783]	[218,429]	3	hSpCas9	negative selection	1300758
55301586	55301609	19	-	26627737	RPE1	viability after 15 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.2050282732266707	[811]	[127,267]	-1	hSpCas9	negative selection	1300759
55302118	55302141	19	+	26627737	RPE1	viability after 15 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.6559859145288658	[2307]	[422,405]	-4	hSpCas9	negative selection	1300760
55287026	55287049	19	+	26627737	RPE1	viability after 18 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	-0.08959093936710943	[1011]	[275,235]	0	hSpCas9	negative selection	1383070
55289483	55289506	19	-	26627737	RPE1	viability after 18 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.38863551301830856	[2252]	[474,1138]	2	hSpCas9	negative selection	1383071
55294113	55294136	19	-	26627737	RPE1	viability after 18 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.8213703323247281	[491]	[281,183]	5	hSpCas9	negative selection	1383072
55294379	55294402	19	-	26627737	RPE1	viability after 18 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.6843895716641117	[783]	[281,401]	4	hSpCas9	negative selection	1383073
55301586	55301609	19	-	26627737	RPE1	viability after 18 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.4602927030754204	[811]	[210,103]	-3	hSpCas9	negative selection	1383074
55302118	55302141	19	+	26627737	RPE1	viability after 18 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.2070076419847655	[2307]	[527,551]	-1	hSpCas9	negative selection	1383075
55287026	55287049	19	+	26627737	HeLa	viability after 8 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.7861668127397854	[315]	[205,401,105]	6	hSpCas9	negative selection	1465385
55289483	55289506	19	-	26627737	HeLa	viability after 8 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	-0.016770855870837043	[1298]	[732,637,357]	0	hSpCas9	negative selection	1465386
55294113	55294136	19	-	26627737	HeLa	viability after 8 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	8.382956486793342	[0]	[260,154,51]	9	hSpCas9	negative selection	1465387
55294379	55294402	19	-	26627737	HeLa	viability after 8 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.385060761025656	[590]	[167,94,312]	-4	hSpCas9	negative selection	1465388
55301586	55301609	19	-	26627737	HeLa	viability after 8 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	1.548377924357928	[144]	[292,136,149]	9	hSpCas9	negative selection	1465389
55302118	55302141	19	+	26627737	HeLa	viability after 8 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.670189583273781	[785]	[173,338,128]	-6	hSpCas9	negative selection	1465390
55287026	55287049	19	+	26627737	HeLa	viability after 12 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	1.0552373972165636	[315]	[158,439,193]	7	hSpCas9	negative selection	1547700
55289483	55289506	19	-	26627737	HeLa	viability after 12 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.137190554895823	[1298]	[856,598,321]	1	hSpCas9	negative selection	1547701
55294113	55294136	19	-	26627737	HeLa	viability after 12 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	8.366112621477388	[0]	[296,48,76]	9	hSpCas9	negative selection	1547702
55294379	55294402	19	-	26627737	HeLa	viability after 12 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.39685371229790295	[590]	[215,226,109]	-4	hSpCas9	negative selection	1547703
55301586	55301609	19	-	26627737	HeLa	viability after 12 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	1.195338906448236	[144]	[223,72,123]	8	hSpCas9	negative selection	1547704
55302118	55302141	19	+	26627737	HeLa	viability after 12 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	0.19754183290968585	[785]	[86,628,365]	1	hSpCas9	negative selection	1547705
55287026	55287049	19	+	26627737	HeLa	viability after 15 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.9621504633015945	[315]	[342,261,136]	7	hSpCas9	negative selection	1630015
55289483	55289506	19	-	26627737	HeLa	viability after 15 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	-0.000283167206378776	[1298]	[569,554,454]	0	hSpCas9	negative selection	1630016
55294113	55294136	19	-	26627737	HeLa	viability after 15 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	8.157649890881173	[0]	[84,173,87]	9	hSpCas9	negative selection	1630017
55294379	55294402	19	-	26627737	HeLa	viability after 15 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.14763067361799065	[590]	[222,287,290]	1	hSpCas9	negative selection	1630018
55301586	55301609	19	-	26627737	HeLa	viability after 15 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.4895693710964766	[144]	[66,84,97]	4	hSpCas9	negative selection	1630019
55302118	55302141	19	+	26627737	HeLa	viability after 15 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	0.23650724196091555	[785]	[123,345,687]	2	hSpCas9	negative selection	1630020
55287026	55287049	19	+	26627737	HeLa	viability after 18 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.9963769761572077	[315]	[236,222,136]	7	hSpCas9	negative selection	1712330
55289483	55289506	19	-	26627737	HeLa	viability after 18 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.06352167332783498	[1298]	[418,471,454]	0	hSpCas9	negative selection	1712331
55294113	55294136	19	-	26627737	HeLa	viability after 18 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	8.164692721575719	[0]	[58,142,87]	9	hSpCas9	negative selection	1712332
55294379	55294402	19	-	26627737	HeLa	viability after 18 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.171906227882079	[590]	[153,243,290]	1	hSpCas9	negative selection	1712333
55301586	55301609	19	-	26627737	HeLa	viability after 18 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.483645794454302	[144]	[38,76,97]	4	hSpCas9	negative selection	1712334
55302118	55302141	19	+	26627737	HeLa	viability after 18 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	0.2695765355750166	[785]	[90,297,687]	2	hSpCas9	negative selection	1712335
55287026	55287049	19	+	26627737	HCT116	viability after 6 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	2.2280173148595113	[273]	[195,204]	9	hSpCas9	negative selection	1794645
55289483	55289506	19	-	26627737	HCT116	viability after 6 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.2991177565284113	[1261]	[421,145]	1	hSpCas9	negative selection	1794646
55294113	55294136	19	-	26627737	HCT116	viability after 6 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	1.1099069895162268	[198]	[140,26]	6	hSpCas9	negative selection	1794647
55294379	55294402	19	-	26627737	HCT116	viability after 6 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	1.4878269413320604	[519]	[178,256]	7	hSpCas9	negative selection	1794648
55301586	55301609	19	-	26627737	HCT116	viability after 6 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-1.8422763494145276	[713]	[78,4]	-8	hSpCas9	negative selection	1794649
55302118	55302141	19	+	26627737	HCT116	viability after 6 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	0.48482397101634866	[1803]	[606,280]	2	hSpCas9	negative selection	1794650
55287026	55287049	19	+	26627737	HCT116	viability after 8 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.3526969823702313	[243]	[156,202,154]	4	hSpCas9	negative selection	1876960
55289483	55289506	19	-	26627737	HCT116	viability after 8 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.22803747259736973	[878]	[509,552,636]	2	hSpCas9	negative selection	1876961
55294113	55294136	19	-	26627737	HCT116	viability after 8 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	-0.16595844036751306	[156]	[120,106,4]	-2	hSpCas9	negative selection	1876962
55294379	55294402	19	-	26627737	HCT116	viability after 8 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.10465938270093988	[409]	[192,302,231]	1	hSpCas9	negative selection	1876963
55301586	55301609	19	-	26627737	HCT116	viability after 8 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.6531441386634573	[330]	[97,164,84]	-7	hSpCas9	negative selection	1876964
55302118	55302141	19	+	26627737	HCT116	viability after 8 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.6887621728487878	[955]	[226,371,378]	-7	hSpCas9	negative selection	1876965
55287026	55287049	19	+	26627737	HCT116	viability after 9 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	2.0575335650830913	[273]	[489,157]	9	hSpCas9	negative selection	1959275
55289483	55289506	19	-	26627737	HCT116	viability after 9 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.6059032026145565	[1261]	[394,605]	4	hSpCas9	negative selection	1959276
55294113	55294136	19	-	26627737	HCT116	viability after 9 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.8100374085481394	[198]	[62,116]	6	hSpCas9	negative selection	1959277
55294379	55294402	19	-	26627737	HCT116	viability after 9 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	1.4054774089734743	[519]	[607,177]	8	hSpCas9	negative selection	1959278
55301586	55301609	19	-	26627737	HCT116	viability after 9 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.783656903589644	[713]	[12,187]	-5	hSpCas9	negative selection	1959279
55302118	55302141	19	+	26627737	HCT116	viability after 9 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	0.4393831892039737	[1803]	[574,714]	3	hSpCas9	negative selection	1959280
55287026	55287049	19	+	26627737	HCT116	viability after 12 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.8973503891250856	[243]	[244,197,271]	7	hSpCas9	negative selection	2041590
55289483	55289506	19	-	26627737	HCT116	viability after 12 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.04740757959757125	[878]	[453,346,629]	0	hSpCas9	negative selection	2041591
55294113	55294136	19	-	26627737	HCT116	viability after 12 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.2877336153708039	[156]	[195,26,68]	3	hSpCas9	negative selection	2041592
55294379	55294402	19	-	26627737	HCT116	viability after 12 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.028667611994456776	[409]	[160,238,264]	0	hSpCas9	negative selection	2041593
55301586	55301609	19	-	26627737	HCT116	viability after 12 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.5545455005124638	[330]	[127,98,126]	-5	hSpCas9	negative selection	2041594
55302118	55302141	19	+	26627737	HCT116	viability after 12 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.49002419497252236	[955]	[390,306,370]	-5	hSpCas9	negative selection	2041595
55287026	55287049	19	+	26627737	HCT116	viability after 15 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.2849598527226946	[243]	[201,143,169]	3	hSpCas9	negative selection	2123905
55289483	55289506	19	-	26627737	HCT116	viability after 15 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.13242259651648403	[878]	[600,610,454]	1	hSpCas9	negative selection	2123906
55294113	55294136	19	-	26627737	HCT116	viability after 15 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.048188591112301116	[156]	[222,22,49]	0	hSpCas9	negative selection	2123907
55294379	55294402	19	-	26627737	HCT116	viability after 15 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.07318402893280274	[409]	[296,275,176]	0	hSpCas9	negative selection	2123908
55301586	55301609	19	-	26627737	HCT116	viability after 15 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.4969304070498486	[330]	[191,77,140]	-5	hSpCas9	negative selection	2123909
55302118	55302141	19	+	26627737	HCT116	viability after 15 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.5825506265084874	[955]	[281,391,414]	-6	hSpCas9	negative selection	2123910
55287026	55287049	19	+	26627737	HCT116	viability after 18 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.771440725283858	[243]	[231,197,172]	6	hSpCas9	negative selection	2206220
55289483	55289506	19	-	26627737	HCT116	viability after 18 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.4359201233254235	[878]	[447,751,509]	4	hSpCas9	negative selection	2206221
55294113	55294136	19	-	26627737	HCT116	viability after 18 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	-1.1493666020360527	[156]	[36,12,54]	-8	hSpCas9	negative selection	2206222
55294379	55294402	19	-	26627737	HCT116	viability after 18 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.12487715037805563	[409]	[198,228,110]	-1	hSpCas9	negative selection	2206223
55301586	55301609	19	-	26627737	HCT116	viability after 18 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.12411528452324834	[330]	[183,92,167]	-1	hSpCas9	negative selection	2206224
55302118	55302141	19	+	26627737	HCT116	viability after 18 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.6501815927162848	[955]	[338,271,272]	-5	hSpCas9	negative selection	2206225
55284431	55284454	19	+	24336569	HL60	viability	ACCAAGGGCACCATGTCGTCCGG	BRSK1	ENSG00000160469	-0.1059650624815105	[1543]	[3035]	-1	hSpCas9	negative selection	2250468
55284516	55284539	19	-	24336569	HL60	viability	GCCCACATATTGGGCGTGCTGGG	BRSK1	ENSG00000160469	-0.12361755204384184	[572]	[1112]	-1	hSpCas9	negative selection	2250469
55284539	55284562	19	-	24336569	HL60	viability	AGCGTCTTCTCCAGCCGATAGGG	BRSK1	ENSG00000160469	2.0872903571054784	[136]	[1231]	9	hSpCas9	negative selection	2250470
55284557	55284580	19	+	24336569	HL60	viability	ACGCTGGGCAAAGGACAGACAGG	BRSK1	ENSG00000160469	-0.08815875320290456	[863]	[1719]	0	hSpCas9	negative selection	2250471
55287000	55287023	19	+	24336569	HL60	viability	CCTGCAGGGCTGGTTAAACTCGG	BRSK1	ENSG00000160469	-0.05535688595941887	[574]	[1170]	0	hSpCas9	negative selection	2250472
55287026	55287049	19	-	24336569	HL60	viability	CCTTCTGACCCGTGATGCAGTGG	BRSK1	ENSG00000160469	2.691125403268032	[2]	[40]	9	hSpCas9	negative selection	2250473
55287049	55287072	19	+	24336569	HL60	viability	TCGCCATCAAGATCGTGAACCGG	BRSK1	ENSG00000160469	0.4940689871723292	[613]	[1829]	4	hSpCas9	negative selection	2250474
55287062	55287085	19	+	24336569	HL60	viability	CGTGAACCGGGAGAAGCTGTCGG	BRSK1	ENSG00000160469	0.013939993106337534	[1491]	[3187]	0	hSpCas9	negative selection	2250475
55287068	55287091	19	+	24336569	HL60	viability	CCGGGAGAAGCTGTCGGAGTCGG	BRSK1	ENSG00000160469	0.39613089813746677	[408]	[1138]	3	hSpCas9	negative selection	2250476
55287080	55287103	19	+	24336569	HL60	viability	GTCGGAGTCGGTGCTGATGAAGG	BRSK1	ENSG00000160469	0.9551828017828403	[446]	[1833]	7	hSpCas9	negative selection	2250477
55284431	55284454	19	+	24336569	KBM7	viability	ACCAAGGGCACCATGTCGTCCGG	BRSK1	ENSG00000160469	0.570831683089789	[1128]	[4573]	5	hSpCas9	negative selection	2317645
55284516	55284539	19	-	24336569	KBM7	viability	GCCCACATATTGGGCGTGCTGGG	BRSK1	ENSG00000160469	0.8948763005950614	[320]	[1627]	7	hSpCas9	negative selection	2317646
55284539	55284562	19	-	24336569	KBM7	viability	AGCGTCTTCTCCAGCCGATAGGG	BRSK1	ENSG00000160469	2.9421915441195314	[80]	[1697]	9	hSpCas9	negative selection	2317647
55284557	55284580	19	+	24336569	KBM7	viability	ACGCTGGGCAAAGGACAGACAGG	BRSK1	ENSG00000160469	-0.05557646349563394	[654]	[1718]	0	hSpCas9	negative selection	2317648
55287000	55287023	19	+	24336569	KBM7	viability	CCTGCAGGGCTGGTTAAACTCGG	BRSK1	ENSG00000160469	0.4268899213672587	[206]	[758]	4	hSpCas9	negative selection	2317649
55287026	55287049	19	-	24336569	KBM7	viability	CCTTCTGACCCGTGATGCAGTGG	BRSK1	ENSG00000160469	-7.148018914689974	[51]	[0]	-9	hSpCas9	negative selection	2317650
55287049	55287072	19	+	24336569	KBM7	viability	TCGCCATCAAGATCGTGAACCGG	BRSK1	ENSG00000160469	0.7154026046332371	[323]	[1450]	6	hSpCas9	negative selection	2317651
55287062	55287085	19	+	24336569	KBM7	viability	CGTGAACCGGGAGAAGCTGTCGG	BRSK1	ENSG00000160469	0.5423269438985413	[752]	[2990]	5	hSpCas9	negative selection	2317652
55287068	55287091	19	+	24336569	KBM7	viability	CCGGGAGAAGCTGTCGGAGTCGG	BRSK1	ENSG00000160469	0.2831001347698926	[275]	[915]	2	hSpCas9	negative selection	2317653
55287080	55287103	19	+	24336569	KBM7	viability	GTCGGAGTCGGTGCTGATGAAGG	BRSK1	ENSG00000160469	-0.5932960271465011	[457]	[827]	-5	hSpCas9	negative selection	2317654
55283986	55284009	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACATCACCATCCGGGGACTCCGG	BRSK1	ENSG00000160469	-2.4548900764071586	[581,151]	[20,6]	-9	dCas9-VP64	positive selection	2459689
55284012	55284035	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGTGCCGGAGAGAAAGGACGAGG	BRSK1	ENSG00000160469	2.394185736756411	[44,108]	[23,160]	7	dCas9-VP64	positive selection	2459690
55283967	55283990	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTAACTTTGGGGAAGGGCCCGG	BRSK1	ENSG00000160469	-1.5918779319468808	[1,134]	[0,8]	-8	dCas9-VP64	positive selection	2459691
55283986	55284009	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACATCACCATCCGGGGACTCCGG	BRSK1	ENSG00000160469	0.9292841761368593	[173,195]	[77,148]	6	dCas9-VP64	positive selection	2554944
55284012	55284035	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGTGCCGGAGAGAAAGGACGAGG	BRSK1	ENSG00000160469	-0.4414251445957277	[41,103]	[20,12]	-4	dCas9-VP64	positive selection	2554945
55283967	55283990	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTAACTTTGGGGAAGGGCCCGG	BRSK1	ENSG00000160469	0.3061563372595593	[71,126]	[19,57]	2	dCas9-VP64	positive selection	2554946
55287026	55287049	19	-	27260157	DLD1	viability	CCTTCTGACCCGTGATGCAGTGG	BRSK1	ENSG00000160469	-0.0924876664133753	[]	[]	0	hSpCas9	negative selection	2575743
55294217	55294240	19	-	27260157	DLD1	viability	CCTCTGGACACGCATAATGGGGG	BRSK1	ENSG00000160469	0.263737486462115	[]	[]	4	hSpCas9	negative selection	2578986
55287270	55287293	19	-	27260157	DLD1	viability	TCTTGTTCTCGTAGACGTCGTGG	BRSK1	ENSG00000160469	-0.868960439364956	[]	[]	-6	hSpCas9	negative selection	2581204
55289573	55289596	19	+	27260157	DLD1	viability	CCGCCAGATTGTGTCTGCGCTGG	BRSK1	ENSG00000160469	-1.4603652122328	[]	[]	-8	hSpCas9	negative selection	2581350
55284431	55284454	19	+	27260157	DLD1	viability	ACCAAGGGCACCATGTCGTCCGG	BRSK1	ENSG00000160469	0.138364901664925	[]	[]	3	hSpCas9	negative selection	2583092
55287026	55287049	19	+	27260157	DLD1	viability	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.729750524090965	[]	[]	8	hSpCas9	negative selection	2585917
55284557	55284580	19	+	27260157	DLD1	viability	ACGCTGGGCAAAGGACAGACAGG	BRSK1	ENSG00000160469	0.555873314797864	[]	[]	8	hSpCas9	negative selection	2604929
55301521	55301544	19	-	27260157	DLD1	viability	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	-0.38266180125633	[]	[]	-3	hSpCas9	negative selection	2607950
55287080	55287103	19	+	27260157	DLD1	viability	GTCGGAGTCGGTGCTGATGAAGG	BRSK1	ENSG00000160469	-0.426802769220324	[]	[]	-3	hSpCas9	negative selection	2609491
55289483	55289506	19	-	27260157	DLD1	viability	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.930404303337632	[]	[]	9	hSpCas9	negative selection	2613134
55284516	55284539	19	-	27260157	DLD1	viability	GCCCACATATTGGGCGTGCTGGG	BRSK1	ENSG00000160469	1.37686223796547	[]	[]	9	hSpCas9	negative selection	2616354
55287000	55287023	19	+	27260157	DLD1	viability	CCTGCAGGGCTGGTTAAACTCGG	BRSK1	ENSG00000160469	-0.793216568744503	[]	[]	-6	hSpCas9	negative selection	2618251
55294342	55294365	19	+	27260157	DLD1	viability	ATGGCCGCCGGGCAGACATGTGG	BRSK1	ENSG00000160469	0.742364359397981	[]	[]	8	hSpCas9	negative selection	2618320
55287002	55287025	19	+	27260157	DLD1	viability	TGCAGGGCTGGTTAAACTCGGGG	BRSK1	ENSG00000160469	-1.15077411596909	[]	[]	-7	hSpCas9	negative selection	2619920
55294029	55294052	19	+	27260157	DLD1	viability	AAAGCCCGAGAACCTGCTTTTGG	BRSK1	ENSG00000160469	0.385627868151812	[]	[]	4	hSpCas9	negative selection	2620447
55287062	55287085	19	+	27260157	DLD1	viability	CGTGAACCGGGAGAAGCTGTCGG	BRSK1	ENSG00000160469	0.070576854353314	[]	[]	3	hSpCas9	negative selection	2621945
55284515	55284538	19	-	27260157	DLD1	viability	CCCACATATTGGGCGTGCTGGGG	BRSK1	ENSG00000160469	0.104232617599798	[]	[]	3	hSpCas9	negative selection	2624225
55287068	55287091	19	+	27260157	DLD1	viability	CCGGGAGAAGCTGTCGGAGTCGG	BRSK1	ENSG00000160469	1.27300580875888	[]	[]	9	hSpCas9	negative selection	2641993
55287049	55287072	19	+	27260157	DLD1	viability	TCGCCATCAAGATCGTGAACCGG	BRSK1	ENSG00000160469	-0.0379152299243341	[]	[]	0	hSpCas9	negative selection	2646612
55287026	55287049	19	-	27260157	HT1080	viability	CCTTCTGACCCGTGATGCAGTGG	BRSK1	ENSG00000160469	-0.342295962756364	[]	[]	-7	hSpCas9	negative selection	2651873
55294217	55294240	19	-	27260157	HT1080	viability	CCTCTGGACACGCATAATGGGGG	BRSK1	ENSG00000160469	0.255902922410285	[]	[]	2	hSpCas9	negative selection	2655116
55287270	55287293	19	-	27260157	HT1080	viability	TCTTGTTCTCGTAGACGTCGTGG	BRSK1	ENSG00000160469	-0.565583156480585	[]	[]	-7	hSpCas9	negative selection	2657334
55289573	55289596	19	+	27260157	HT1080	viability	CCGCCAGATTGTGTCTGCGCTGG	BRSK1	ENSG00000160469	-2.36892405383562	[]	[]	-9	hSpCas9	negative selection	2657480
55284431	55284454	19	+	27260157	HT1080	viability	ACCAAGGGCACCATGTCGTCCGG	BRSK1	ENSG00000160469	0.293463633504502	[]	[]	2	hSpCas9	negative selection	2659222
55287026	55287049	19	+	27260157	HT1080	viability	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.819444588754796	[]	[]	7	hSpCas9	negative selection	2662047
55284557	55284580	19	+	27260157	HT1080	viability	ACGCTGGGCAAAGGACAGACAGG	BRSK1	ENSG00000160469	0.898443883846427	[]	[]	7	hSpCas9	negative selection	2681059
55301521	55301544	19	-	27260157	HT1080	viability	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	-0.69800597648145	[]	[]	-8	hSpCas9	negative selection	2684080
55287080	55287103	19	+	27260157	HT1080	viability	GTCGGAGTCGGTGCTGATGAAGG	BRSK1	ENSG00000160469	0.121451091180237	[]	[]	1	hSpCas9	negative selection	2685621
55289483	55289506	19	-	27260157	HT1080	viability	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	1.612718151778	[]	[]	9	hSpCas9	negative selection	2689264
55284516	55284539	19	-	27260157	HT1080	viability	GCCCACATATTGGGCGTGCTGGG	BRSK1	ENSG00000160469	-0.194654745269825	[]	[]	0	hSpCas9	negative selection	2692484
55287000	55287023	19	+	27260157	HT1080	viability	CCTGCAGGGCTGGTTAAACTCGG	BRSK1	ENSG00000160469	0.111056518437521	[]	[]	1	hSpCas9	negative selection	2694381
55294342	55294365	19	+	27260157	HT1080	viability	ATGGCCGCCGGGCAGACATGTGG	BRSK1	ENSG00000160469	-0.223045704365114	[]	[]	0	hSpCas9	negative selection	2694450
55287002	55287025	19	+	27260157	HT1080	viability	TGCAGGGCTGGTTAAACTCGGGG	BRSK1	ENSG00000160469	-1.70694771709904	[]	[]	-9	hSpCas9	negative selection	2696050
55294029	55294052	19	+	27260157	HT1080	viability	AAAGCCCGAGAACCTGCTTTTGG	BRSK1	ENSG00000160469	1.59671212598301	[]	[]	9	hSpCas9	negative selection	2696577
55287062	55287085	19	+	27260157	HT1080	viability	CGTGAACCGGGAGAAGCTGTCGG	BRSK1	ENSG00000160469	0.561039885486589	[]	[]	5	hSpCas9	negative selection	2698075
55284515	55284538	19	-	27260157	HT1080	viability	CCCACATATTGGGCGTGCTGGGG	BRSK1	ENSG00000160469	0.0595019052764055	[]	[]	0	hSpCas9	negative selection	2700355
55287068	55287091	19	+	27260157	HT1080	viability	CCGGGAGAAGCTGTCGGAGTCGG	BRSK1	ENSG00000160469	0.477142833426593	[]	[]	4	hSpCas9	negative selection	2718123
55287049	55287072	19	+	27260157	HT1080	viability	TCGCCATCAAGATCGTGAACCGG	BRSK1	ENSG00000160469	0.281397141992485	[]	[]	2	hSpCas9	negative selection	2722742
55287026	55287049	19	-	27260157	MKN45	viability	CCTTCTGACCCGTGATGCAGTGG	BRSK1	ENSG00000160469	-0.0362054872124532	[]	[]	0	hSpCas9	negative selection	2728003
55294217	55294240	19	-	27260157	MKN45	viability	CCTCTGGACACGCATAATGGGGG	BRSK1	ENSG00000160469	-0.703790433688163	[]	[]	-7	hSpCas9	negative selection	2731246
55287270	55287293	19	-	27260157	MKN45	viability	TCTTGTTCTCGTAGACGTCGTGG	BRSK1	ENSG00000160469	-0.339709319206871	[]	[]	-1	hSpCas9	negative selection	2733464
55289573	55289596	19	+	27260157	MKN45	viability	CCGCCAGATTGTGTCTGCGCTGG	BRSK1	ENSG00000160469	-1.46170692010059	[]	[]	-8	hSpCas9	negative selection	2733610
55284431	55284454	19	+	27260157	MKN45	viability	ACCAAGGGCACCATGTCGTCCGG	BRSK1	ENSG00000160469	0.441418800839205	[]	[]	6	hSpCas9	negative selection	2735352
55287026	55287049	19	+	27260157	MKN45	viability	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.403953686025928	[]	[]	6	hSpCas9	negative selection	2738177
55284557	55284580	19	+	27260157	MKN45	viability	ACGCTGGGCAAAGGACAGACAGG	BRSK1	ENSG00000160469	1.91906267823322	[]	[]	9	hSpCas9	negative selection	2757189
55301521	55301544	19	-	27260157	MKN45	viability	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	-0.415163174603721	[]	[]	-6	hSpCas9	negative selection	2760210
55287080	55287103	19	+	27260157	MKN45	viability	GTCGGAGTCGGTGCTGATGAAGG	BRSK1	ENSG00000160469	0.190591914747835	[]	[]	5	hSpCas9	negative selection	2761751
55289483	55289506	19	-	27260157	MKN45	viability	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	1.75503907380355	[]	[]	9	hSpCas9	negative selection	2765394
55284516	55284539	19	-	27260157	MKN45	viability	GCCCACATATTGGGCGTGCTGGG	BRSK1	ENSG00000160469	0.484413912428438	[]	[]	6	hSpCas9	negative selection	2768614
55287000	55287023	19	+	27260157	MKN45	viability	CCTGCAGGGCTGGTTAAACTCGG	BRSK1	ENSG00000160469	0.144519062523562	[]	[]	5	hSpCas9	negative selection	2770511
55294342	55294365	19	+	27260157	MKN45	viability	ATGGCCGCCGGGCAGACATGTGG	BRSK1	ENSG00000160469	-0.92847645774801	[]	[]	-7	hSpCas9	negative selection	2770580
55287002	55287025	19	+	27260157	MKN45	viability	TGCAGGGCTGGTTAAACTCGGGG	BRSK1	ENSG00000160469	-2.75477126711903	[]	[]	-9	hSpCas9	negative selection	2772180
55294029	55294052	19	+	27260157	MKN45	viability	AAAGCCCGAGAACCTGCTTTTGG	BRSK1	ENSG00000160469	1.05521568643288	[]	[]	8	hSpCas9	negative selection	2772707
55287062	55287085	19	+	27260157	MKN45	viability	CGTGAACCGGGAGAAGCTGTCGG	BRSK1	ENSG00000160469	0.791739885027509	[]	[]	7	hSpCas9	negative selection	2774205
55284515	55284538	19	-	27260157	MKN45	viability	CCCACATATTGGGCGTGCTGGGG	BRSK1	ENSG00000160469	0.743174346536355	[]	[]	7	hSpCas9	negative selection	2776485
55287068	55287091	19	+	27260157	MKN45	viability	CCGGGAGAAGCTGTCGGAGTCGG	BRSK1	ENSG00000160469	1.33889475924663	[]	[]	9	hSpCas9	negative selection	2794253
55287049	55287072	19	+	27260157	MKN45	viability	TCGCCATCAAGATCGTGAACCGG	BRSK1	ENSG00000160469	0.485947253918201	[]	[]	6	hSpCas9	negative selection	2798872
55287026	55287049	19	-	27260157	RKO	viability	CCTTCTGACCCGTGATGCAGTGG	BRSK1	ENSG00000160469	-0.108024271538303	[]	[]	0	hSpCas9	negative selection	2804133
55294217	55294240	19	-	27260157	RKO	viability	CCTCTGGACACGCATAATGGGGG	BRSK1	ENSG00000160469	-0.414664977453694	[]	[]	-6	hSpCas9	negative selection	2807376
55287270	55287293	19	-	27260157	RKO	viability	TCTTGTTCTCGTAGACGTCGTGG	BRSK1	ENSG00000160469	-0.106157317499221	[]	[]	0	hSpCas9	negative selection	2809594
55289573	55289596	19	+	27260157	RKO	viability	CCGCCAGATTGTGTCTGCGCTGG	BRSK1	ENSG00000160469	-0.988370729943958	[]	[]	-8	hSpCas9	negative selection	2809740
55284431	55284454	19	+	27260157	RKO	viability	ACCAAGGGCACCATGTCGTCCGG	BRSK1	ENSG00000160469	0.14809226959703	[]	[]	0	hSpCas9	negative selection	2811482
55287026	55287049	19	+	27260157	RKO	viability	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.190745227037854	[]	[]	1	hSpCas9	negative selection	2814307
55284557	55284580	19	+	27260157	RKO	viability	ACGCTGGGCAAAGGACAGACAGG	BRSK1	ENSG00000160469	1.16233632722744	[]	[]	9	hSpCas9	negative selection	2833319
55301521	55301544	19	-	27260157	RKO	viability	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	-0.718792656609964	[]	[]	-7	hSpCas9	negative selection	2836340
55287080	55287103	19	+	27260157	RKO	viability	GTCGGAGTCGGTGCTGATGAAGG	BRSK1	ENSG00000160469	0.0433653466384363	[]	[]	0	hSpCas9	negative selection	2837881
55289483	55289506	19	-	27260157	RKO	viability	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	1.10246940810897	[]	[]	9	hSpCas9	negative selection	2841524
55284516	55284539	19	-	27260157	RKO	viability	GCCCACATATTGGGCGTGCTGGG	BRSK1	ENSG00000160469	0.95148740199017	[]	[]	8	hSpCas9	negative selection	2844744
55287000	55287023	19	+	27260157	RKO	viability	CCTGCAGGGCTGGTTAAACTCGG	BRSK1	ENSG00000160469	-0.147479722724167	[]	[]	0	hSpCas9	negative selection	2846641
55294342	55294365	19	+	27260157	RKO	viability	ATGGCCGCCGGGCAGACATGTGG	BRSK1	ENSG00000160469	-0.813970627115787	[]	[]	-7	hSpCas9	negative selection	2846710
55287002	55287025	19	+	27260157	RKO	viability	TGCAGGGCTGGTTAAACTCGGGG	BRSK1	ENSG00000160469	-1.67658415684691	[]	[]	-9	hSpCas9	negative selection	2848310
55294029	55294052	19	+	27260157	RKO	viability	AAAGCCCGAGAACCTGCTTTTGG	BRSK1	ENSG00000160469	0.952939883398085	[]	[]	8	hSpCas9	negative selection	2848837
55287062	55287085	19	+	27260157	RKO	viability	CGTGAACCGGGAGAAGCTGTCGG	BRSK1	ENSG00000160469	0.130153963671139	[]	[]	0	hSpCas9	negative selection	2850335
55284515	55284538	19	-	27260157	RKO	viability	CCCACATATTGGGCGTGCTGGGG	BRSK1	ENSG00000160469	0.0710564962083359	[]	[]	0	hSpCas9	negative selection	2852615
55287068	55287091	19	+	27260157	RKO	viability	CCGGGAGAAGCTGTCGGAGTCGG	BRSK1	ENSG00000160469	0.89287561556199	[]	[]	8	hSpCas9	negative selection	2870383
55287049	55287072	19	+	27260157	RKO	viability	TCGCCATCAAGATCGTGAACCGG	BRSK1	ENSG00000160469	-0.6533600427507	[]	[]	-7	hSpCas9	negative selection	2875002
55287026	55287049	19	-	27260157	SF268	viability	CCTTCTGACCCGTGATGCAGTGG	BRSK1	ENSG00000160469	-0.617395415245368	[]	[]	-5	hSpCas9	negative selection	2880263
55294217	55294240	19	-	27260157	SF268	viability	CCTCTGGACACGCATAATGGGGG	BRSK1	ENSG00000160469	0.278125700784047	[]	[]	4	hSpCas9	negative selection	2883506
55287270	55287293	19	-	27260157	SF268	viability	TCTTGTTCTCGTAGACGTCGTGG	BRSK1	ENSG00000160469	-0.732874203026633	[]	[]	-5	hSpCas9	negative selection	2885724
55289573	55289596	19	+	27260157	SF268	viability	CCGCCAGATTGTGTCTGCGCTGG	BRSK1	ENSG00000160469	-0.811363395944027	[]	[]	-6	hSpCas9	negative selection	2885870
55284431	55284454	19	+	27260157	SF268	viability	ACCAAGGGCACCATGTCGTCCGG	BRSK1	ENSG00000160469	-0.0968045944950329	[]	[]	0	hSpCas9	negative selection	2887612
55287026	55287049	19	+	27260157	SF268	viability	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.945034797249362	[]	[]	9	hSpCas9	negative selection	2890437
55284557	55284580	19	+	27260157	SF268	viability	ACGCTGGGCAAAGGACAGACAGG	BRSK1	ENSG00000160469	1.19963018363152	[]	[]	9	hSpCas9	negative selection	2909449
55301521	55301544	19	-	27260157	SF268	viability	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	-0.317154242108675	[]	[]	-2	hSpCas9	negative selection	2912470
55287080	55287103	19	+	27260157	SF268	viability	GTCGGAGTCGGTGCTGATGAAGG	BRSK1	ENSG00000160469	-0.8021895146223	[]	[]	-6	hSpCas9	negative selection	2914011
55289483	55289506	19	-	27260157	SF268	viability	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.543934072496123	[]	[]	8	hSpCas9	negative selection	2917654
55284516	55284539	19	-	27260157	SF268	viability	GCCCACATATTGGGCGTGCTGGG	BRSK1	ENSG00000160469	0.8013912615556	[]	[]	8	hSpCas9	negative selection	2920874
55287000	55287023	19	+	27260157	SF268	viability	CCTGCAGGGCTGGTTAAACTCGG	BRSK1	ENSG00000160469	-1.11090188788317	[]	[]	-7	hSpCas9	negative selection	2922771
55294342	55294365	19	+	27260157	SF268	viability	ATGGCCGCCGGGCAGACATGTGG	BRSK1	ENSG00000160469	0.313845291955753	[]	[]	4	hSpCas9	negative selection	2922840
55287002	55287025	19	+	27260157	SF268	viability	TGCAGGGCTGGTTAAACTCGGGG	BRSK1	ENSG00000160469	-2.21704447046008	[]	[]	-9	hSpCas9	negative selection	2924440
55294029	55294052	19	+	27260157	SF268	viability	AAAGCCCGAGAACCTGCTTTTGG	BRSK1	ENSG00000160469	0.657409597937847	[]	[]	8	hSpCas9	negative selection	2924967
55287062	55287085	19	+	27260157	SF268	viability	CGTGAACCGGGAGAAGCTGTCGG	BRSK1	ENSG00000160469	0.363139341330181	[]	[]	4	hSpCas9	negative selection	2926465
55284515	55284538	19	-	27260157	SF268	viability	CCCACATATTGGGCGTGCTGGGG	BRSK1	ENSG00000160469	0.858349863546151	[]	[]	9	hSpCas9	negative selection	2928745
55287068	55287091	19	+	27260157	SF268	viability	CCGGGAGAAGCTGTCGGAGTCGG	BRSK1	ENSG00000160469	0.888743006913711	[]	[]	9	hSpCas9	negative selection	2946513
55287049	55287072	19	+	27260157	SF268	viability	TCGCCATCAAGATCGTGAACCGG	BRSK1	ENSG00000160469	-0.527794137848206	[]	[]	-4	hSpCas9	negative selection	2951132
55284431	55284454	19	+	27013184	SW480	treatment with recombinant TRAIL	ACCAAGGGCACCATGTCGTCCGG	BRSK1	ENSG00000160469	0.9784124922618616	[174,288]	[291,51]	4	hSpCas9	positive selection	2962652
55284432	55284455	19	+	27013184	SW480	treatment with recombinant TRAIL	CCAAGGGCACCATGTCGTCCGGG	BRSK1	ENSG00000160469	-3.3961908363797266	[48,79]	[2,1]	-9	hSpCas9	positive selection	2962653
55284433	55284456	19	+	27013184	SW480	treatment with recombinant TRAIL	CAAGGGCACCATGTCGTCCGGGG	BRSK1	ENSG00000160469	-1.3800826461847582	[284,308]	[20,88]	-6	hSpCas9	positive selection	2962654
55284439	55284462	19	+	27013184	SW480	treatment with recombinant TRAIL	CACCATGTCGTCCGGGGCCAAGG	BRSK1	ENSG00000160469	-0.8614532968812366	[486,733]	[174,95]	-4	hSpCas9	positive selection	2962655
55284442	55284465	19	+	27013184	SW480	treatment with recombinant TRAIL	CATGTCGTCCGGGGCCAAGGAGG	BRSK1	ENSG00000160469	0.38530795922272065	[177,269]	[170,56]	2	hSpCas9	positive selection	2962656
55284443	55284466	19	+	27013184	SW480	treatment with recombinant TRAIL	ATGTCGTCCGGGGCCAAGGAGGG	BRSK1	ENSG00000160469	0.3799923851122553	[157,243]	[47,199]	2	hSpCas9	positive selection	2962657
55284514	55284537	19	+	27013184	SW480	treatment with recombinant TRAIL	ACCCCAGCACGCCCAATATGTGG	BRSK1	ENSG00000160469	-0.17569181445802773	[667,673]	[247,267]	-1	hSpCas9	positive selection	2962658
55284515	55284538	19	+	27013184	SW480	treatment with recombinant TRAIL	CCCCAGCACGCCCAATATGTGGG	BRSK1	ENSG00000160469	0.08531174733549607	[991,951]	[529,325]	0	hSpCas9	positive selection	2962659
55284525	55284548	19	+	27013184	SW480	treatment with recombinant TRAIL	CCCAATATGTGGGCCCCTATCGG	BRSK1	ENSG00000160469	-0.2996908379438832	[1147,1565]	[363,618]	-1	hSpCas9	positive selection	2962660
55284529	55284552	19	+	27013184	SW480	treatment with recombinant TRAIL	ATATGTGGGCCCCTATCGGCTGG	BRSK1	ENSG00000160469	0.8625498882065491	[42,110]	[10,124]	4	hSpCas9	positive selection	2962661
55302797	55302820	19	+	27013184	SW480	treatment with recombinant TRAIL	CTAGAGAGCATGGCATCACTGGG	BRSK1	ENSG00000160469	0.16208895334472806	[40,98]	[46,11]	0	hSpCas9	positive selection	2962662
55302807	55302830	19	+	27013184	SW480	treatment with recombinant TRAIL	TGGCATCACTGGGCTGCTTCAGG	BRSK1	ENSG00000160469	-0.11629025795613024	[614,816]	[226,358]	0	hSpCas9	positive selection	2962663
55303335	55303358	19	+	27013184	SW480	treatment with recombinant TRAIL	TTATCTGCTTTTGGATCGGAAGG	BRSK1	ENSG00000160469	-1.1494509226163425	[240,275]	[82,2]	-5	hSpCas9	positive selection	2962664
55303340	55303363	19	+	27013184	SW480	treatment with recombinant TRAIL	TGCTTTTGGATCGGAAGGAGCGG	BRSK1	ENSG00000160469	-0.36620887765785204	[77,167]	[31,50]	-2	hSpCas9	positive selection	2962665
55303356	55303379	19	+	27013184	SW480	treatment with recombinant TRAIL	GGAGCGGTATCCCAGCTGTGAGG	BRSK1	ENSG00000160469	-0.7866090446054217	[411,499]	[96,135]	-4	hSpCas9	positive selection	2962666
55303387	55303410	19	+	27013184	SW480	treatment with recombinant TRAIL	CTGCCTCCCCGGAATGATGTTGG	BRSK1	ENSG00000160469	-0.5364912181766948	[319,334]	[95,98]	-2	hSpCas9	positive selection	2962667
55284512	55284535	19	-	27013184	SW480	treatment with recombinant TRAIL	ACATATTGGGCGTGCTGGGGTGG	BRSK1	ENSG00000160469	1.2587661617685528	[328,663]	[557,410]	6	hSpCas9	positive selection	2962668
55284515	55284538	19	-	27013184	SW480	treatment with recombinant TRAIL	CCCACATATTGGGCGTGCTGGGG	BRSK1	ENSG00000160469	0.41544619931844284	[555,540]	[313,318]	2	hSpCas9	positive selection	2962669
55284516	55284539	19	-	27013184	SW480	treatment with recombinant TRAIL	GCCCACATATTGGGCGTGCTGGG	BRSK1	ENSG00000160469	3.342257772567991	[72,42]	[224,308]	9	hSpCas9	positive selection	2962670
55284517	55284540	19	-	27013184	SW480	treatment with recombinant TRAIL	GGCCCACATATTGGGCGTGCTGG	BRSK1	ENSG00000160469	-2.2425351144214667	[213,282]	[9,39]	-8	hSpCas9	positive selection	2962671
55284525	55284548	19	-	27013184	SW480	treatment with recombinant TRAIL	CCGATAGGGGCCCACATATTGGG	BRSK1	ENSG00000160469	-1.0040473410804185	[482,271]	[81,84]	-4	hSpCas9	positive selection	2962672
55284526	55284549	19	-	27013184	SW480	treatment with recombinant TRAIL	GCCGATAGGGGCCCACATATTGG	BRSK1	ENSG00000160469	-1.822160035464322	[489,411]	[7,122]	-7	hSpCas9	positive selection	2962673
55284538	55284561	19	-	27013184	SW480	treatment with recombinant TRAIL	GCGTCTTCTCCAGCCGATAGGGG	BRSK1	ENSG00000160469	-0.3782104221983601	[437,551]	[179,137]	-2	hSpCas9	positive selection	2962674
55284539	55284562	19	-	27013184	SW480	treatment with recombinant TRAIL	AGCGTCTTCTCCAGCCGATAGGG	BRSK1	ENSG00000160469	0.1533272366204852	[29,87]	[17,39]	0	hSpCas9	positive selection	2962675
55284540	55284563	19	-	27013184	SW480	treatment with recombinant TRAIL	CAGCGTCTTCTCCAGCCGATAGG	BRSK1	ENSG00000160469	2.0027190377846393	[6,41]	[49,24]	8	hSpCas9	positive selection	2962676
55303298	55303321	19	-	27013184	SW480	treatment with recombinant TRAIL	TTGGTTCTCCCTAAGGCAGGGGG	BRSK1	ENSG00000160469	0.5488540661563205	[186,342]	[197,112]	2	hSpCas9	positive selection	2962677
55303300	55303323	19	-	27013184	SW480	treatment with recombinant TRAIL	TCTTGGTTCTCCCTAAGGCAGGG	BRSK1	ENSG00000160469	-0.49424213287175656	[97,104]	[30,30]	-2	hSpCas9	positive selection	2962678
55303386	55303409	19	-	27013184	SW480	treatment with recombinant TRAIL	CAACATCATTCCGGGGAGGCAGG	BRSK1	ENSG00000160469	-0.20396956662202523	[186,318]	[66,128]	-1	hSpCas9	positive selection	2962679
55303390	55303413	19	-	27013184	SW480	treatment with recombinant TRAIL	TCACCAACATCATTCCGGGGAGG	BRSK1	ENSG00000160469	1.428950933260968	[201,206]	[108,419]	6	hSpCas9	positive selection	2962680
55303393	55303416	19	-	27013184	SW480	treatment with recombinant TRAIL	TTCTCACCAACATCATTCCGGGG	BRSK1	ENSG00000160469	1.0823179989798406	[28,198]	[133,44]	5	hSpCas9	positive selection	2962681
55301602	55301625	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGATTGCCAGAGCCTCCTGAGGG	BRSK1	ENSG00000160469	-0.1825522969027442	[3,3]	[2,2]	-3	hSpCas9	positive selection	2973757
55289573	55289596	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	0.11041685184042864	[3,3]	[3,3]	2	hSpCas9	positive selection	2973758
55301521	55301544	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	0.44797723064979167	[3,3]	[3,5]	8	hSpCas9	positive selection	2973759
55302742	55302765	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGCTCCGCATGGCTACCCGGCGG	BRSK1	ENSG00000160469	0.2744654374895061	[4,3]	[3,4]	6	hSpCas9	positive selection	2973760
55301602	55301625	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGATTGCCAGAGCCTCCTGAGGG	BRSK1	ENSG00000160469	0.04599436956152432	[3,3]	[3,1]	0	hSpCas9	positive selection	3041615
55289573	55289596	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.7554652841859927	[3,3]	[2,0]	-8	hSpCas9	positive selection	3041616
55301521	55301544	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	0.37857154526945636	[3,3]	[3,3]	6	hSpCas9	positive selection	3041617
55302742	55302765	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGCTCCGCATGGCTACCCGGCGG	BRSK1	ENSG00000160469	-0.06969334784119574	[4,4]	[3,1]	-1	hSpCas9	positive selection	3041618
55294387	55294410		-	24336571	A375	resistance to PLX after 7 days	AGGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.6096267264937296	[16,13]	[32,14]	9	hSpCas9	positive selection	3151709
55289576	55289599		-	24336571	A375	resistance to PLX after 7 days	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.04032494065838816	[12,11]	[13,11]	1	hSpCas9	positive selection	3151715
55289483	55289506		-	24336571	A375	resistance to PLX after 7 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	-0.20359353847054398	[16,15]	[13,13]	-6	hSpCas9	positive selection	3151726
55294387	55294410		-	24336571	A375	resistance to PLX after 14 days	AGGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	3.362201283369318	[20,12]	[67,99]	9	hSpCas9	positive selection	3209502
55289576	55289599		-	24336571	A375	resistance to PLX after 14 days	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	-0.03606991941160867	[6,13]	[4,4]	0	hSpCas9	positive selection	3209508
55289483	55289506		-	24336571	A375	resistance to PLX after 14 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.5769614335107229	[18,10]	[9,9]	5	hSpCas9	positive selection	3209519
55294387	55294410		-	24336571	A375	viability after 7 days	AGGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	-0.09412940372909745	[16]	[16,13]	-1	hSpCas9	negative selection	3267295
55289576	55289599		-	24336571	A375	viability after 7 days	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.08782070433220525	[12]	[12,11]	1	hSpCas9	negative selection	3267301
55289483	55289506		-	24336571	A375	viability after 7 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.3549823233509137	[12]	[16,15]	5	hSpCas9	negative selection	3267312
55294387	55294410		-	24336571	A375	viability after 14 days	AGGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.06139603184744169	[16]	[20,12]	0	hSpCas9	negative selection	3325088
55289576	55289599		-	24336571	A375	viability after 14 days	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	-0.15061420279444238	[12]	[6,13]	-2	hSpCas9	negative selection	3325094
55289483	55289506		-	24336571	A375	viability after 14 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.25628670335476145	[12]	[18,10]	3	hSpCas9	negative selection	3325105
55289551	55289574	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	1.0383475567523082	[72,75]	[0,0]	5	hSpCas9	positive selection	3339128
55289576	55289599	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	-0.5784558868759984	[221,234]	[0,0]	-4	hSpCas9	positive selection	3339129
55302763	55302786	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.5174463484620588	[88,124]	[0,0]	2	hSpCas9	positive selection	3339130
55302787	55302810	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.28004628794591846	[125,125]	[0,0]	1	hSpCas9	positive selection	3358369
55294379	55294402	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	1.5024387092823666	[53,53]	[0,0]	6	hSpCas9	positive selection	3358370
55294376	55294399	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.9618423090163265	[297,297]	[0,0]	-6	hSpCas9	positive selection	3358371
55301601	55301624	19	+	26780180	HT29	viability (Avana library 4 designs)	AGATTGCCAGAGCCTCCTGAGGG	BRSK1	ENSG00000160469	1.23572210507362	[]	[]	5	hSpCas9	negative selection	3409958
55289573	55289596	19	-	26780180	HT29	viability (Avana library 4 designs)	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	0.882613021383563	[]	[]	3	hSpCas9	negative selection	3409959
55301521	55301544	19	-	26780180	HT29	viability (Avana library 4 designs)	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	0.90604312564157	[]	[]	3	hSpCas9	negative selection	3409960
55302742	55302765	19	-	26780180	HT29	viability (Avana library 4 designs)	GGCTCCGCATGGCTACCCGGCGG	BRSK1	ENSG00000160469	0.796916197912445	[]	[]	3	hSpCas9	negative selection	3409961
55301601	55301624	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGATTGCCAGAGCCTCCTGAGGG	BRSK1	ENSG00000160469	2.46246413624833	[]	[]	3	hSpCas9	negative selection	3484224
55302742	55302765	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCCGCATGGCTACCCGGCGG	BRSK1	ENSG00000160469	3.21374250256721	[]	[]	5	hSpCas9	negative selection	3484225
55301521	55301544	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	6.72770177004062	[]	[]	9	hSpCas9	negative selection	3484226
55289573	55289596	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-3.48036184506153	[]	[]	-4	hSpCas9	negative selection	3484227
55287230	55287253	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.00205322978872785	[]	[]	0	hSpCas9	negative selection	3484228
55284542	55284565	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATCGGCTGGAGAAGACGCTGGG	BRSK1	ENSG00000160469	-7.39815515844875	[]	[]	-6	hSpCas9	negative selection	3484229
55301601	55301624	19	+	26780180	A375	viability (Avana lentiGuide)	AGATTGCCAGAGCCTCCTGAGGG	BRSK1	ENSG00000160469	0.804384113672384	[]	[]	1	hSpCas9	negative selection	3592883
55302742	55302765	19	-	26780180	A375	viability (Avana lentiGuide)	GGCTCCGCATGGCTACCCGGCGG	BRSK1	ENSG00000160469	3.73507941632747	[]	[]	3	hSpCas9	negative selection	3592884
55301521	55301544	19	-	26780180	A375	viability (Avana lentiGuide)	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	-2.04160617677161	[]	[]	-3	hSpCas9	negative selection	3592885
55289573	55289596	19	-	26780180	A375	viability (Avana lentiGuide)	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-3.22320974423416	[]	[]	-5	hSpCas9	negative selection	3592886
55287230	55287253	19	-	26780180	A375	viability (Avana lentiGuide)	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.471660885827801	[]	[]	0	hSpCas9	negative selection	3592887
55284542	55284565	19	+	26780180	A375	viability (Avana lentiGuide)	TATCGGCTGGAGAAGACGCTGGG	BRSK1	ENSG00000160469	-2.74176141640148	[]	[]	-5	hSpCas9	negative selection	3592888
55301601	55301624	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGATTGCCAGAGCCTCCTGAGGG	BRSK1	ENSG00000160469	0.10538269613582574	[4]	[5,5]	2	hSpCas9	positive selection	3701542
55302742	55302765	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCCGCATGGCTACCCGGCGG	BRSK1	ENSG00000160469	0.12272951167395629	[5]	[5,5]	3	hSpCas9	positive selection	3701543
55301521	55301544	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	0.4221717908271474	[4]	[6,6]	9	hSpCas9	positive selection	3701544
55289573	55289596	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.18364928083837934	[5]	[5,3]	-3	hSpCas9	positive selection	3701545
55287230	55287253	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.10603946108338323	[5]	[5,5]	2	hSpCas9	positive selection	3701546
55284542	55284565	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATCGGCTGGAGAAGACGCTGGG	BRSK1	ENSG00000160469	-0.6325141772745553	[4]	[2,2]	-7	hSpCas9	positive selection	3701547
55301601	55301624	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGATTGCCAGAGCCTCCTGAGGG	BRSK1	ENSG00000160469	0.0474965492987908	[5]	[3,5]	1	hSpCas9	positive selection	3810149
55302742	55302765	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCCGCATGGCTACCCGGCGG	BRSK1	ENSG00000160469	-0.08037686356339291	[6]	[5,4]	-1	hSpCas9	positive selection	3810150
55301521	55301544	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGGAGGTTGTCGTCATCAAAGGG	BRSK1	ENSG00000160469	-0.45539792597991313	[5]	[1,4]	-5	hSpCas9	positive selection	3810151
55289573	55289596	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	0.020394260150378513	[5]	[3,5]	0	hSpCas9	positive selection	3810152
55287230	55287253	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.3618403009371096	[6]	[6,6]	9	hSpCas9	positive selection	3810153
55284542	55284565	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATCGGCTGGAGAAGACGCTGGG	BRSK1	ENSG00000160469	0.08676527974719339	[5]	[5,4]	2	hSpCas9	positive selection	3810154
55289576	55289599	19	-	26780180	A375	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.785732168747747	[]	[]	3	hSpCas9	negative selection	3918424
55294376	55294399	19	+	26780180	A375	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.847167490765774	[]	[]	3	hSpCas9	negative selection	3918425
55302787	55302810	19	+	26780180	A375	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	1.26100765135795	[]	[]	6	hSpCas9	negative selection	3918426
55302763	55302786	19	+	26780180	A375	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	1.51544883141362	[]	[]	8	hSpCas9	negative selection	3918427
55289551	55289574	19	-	26780180	A375	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.891343299587386	[]	[]	4	hSpCas9	negative selection	3918428
55294379	55294402	19	-	26780180	A375	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	1.06411413273574	[]	[]	5	hSpCas9	negative selection	3918429
55289576	55289599	19	-	26780180	HT29	viability (GeCKOv2 library)	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	1.40959406271649	[]	[]	7	hSpCas9	negative selection	4026390
55294376	55294399	19	+	26780180	HT29	viability (GeCKOv2 library)	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.361742352445414	[]	[]	1	hSpCas9	negative selection	4026391
55302787	55302810	19	+	26780180	HT29	viability (GeCKOv2 library)	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	1.47001054415814	[]	[]	7	hSpCas9	negative selection	4026392
55302763	55302786	19	+	26780180	HT29	viability (GeCKOv2 library)	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	1.40164245614292	[]	[]	7	hSpCas9	negative selection	4026393
55289551	55289574	19	-	26780180	HT29	viability (GeCKOv2 library)	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.497739898548079	[]	[]	1	hSpCas9	negative selection	4026394
55294379	55294402	19	-	26780180	HT29	viability (GeCKOv2 library)	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	1.62758222303465	[]	[]	8	hSpCas9	negative selection	4026395
55294387	55294410	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.7166487849696042	[4]	[3,6]	9	hSpCas9	positive selection	4178229
55289576	55289599	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.3138556490700882	[2]	[2,2]	7	hSpCas9	positive selection	4178240
55289483	55289506	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.6656263255986227	[3]	[4,3]	9	hSpCas9	positive selection	4178251
55294387	55294410	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.45626611338944023	[3]	[3,4,1,0]	3	hSpCas9	positive selection	4242251
55289576	55289599	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	1.2315158836967222	[3]	[3,0,3,5]	8	hSpCas9	positive selection	4242262
55289483	55289506	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.793566412356707	[2]	[2,4,3,0]	5	hSpCas9	positive selection	4242273
55289551	55289574	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.6887241413633994	[1]	[3,2]	9	hSpCas9	positive selection	4258549
55289576	55289599	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	-0.34582481021733297	[3]	[2,1]	-6	hSpCas9	positive selection	4258550
55302763	55302786	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	-0.27761361145077856	[3]	[3,0]	-5	hSpCas9	positive selection	4258551
55302787	55302810	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.5208425784854267	[2]	[1,0]	-8	hSpCas9	positive selection	4322833
55294379	55294402	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.1546080095439093	[1]	[2,0]	-3	hSpCas9	positive selection	4322834
55294376	55294399	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.04805921721375195	[4]	[3,2]	1	hSpCas9	positive selection	4322835
55294220	55294242	19	-	27760321	OCIAML3	viability	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.2223600747879283	[462,349]	[320,428]	2	hSpCas9	negative selection	4382336
55294387	55294409	19	-	27760321	OCIAML3	viability	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.4286545198269165	[970,884]	[935,1028]	5	hSpCas9	negative selection	4382337
55301613	55301635	19	-	27760321	OCIAML3	viability	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	-0.11375719484539565	[360,325]	[254,238]	-1	hSpCas9	negative selection	4382338
55302735	55302757	19	-	27760321	OCIAML3	viability	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.6624655605050207	[1006,789]	[1014,1221]	7	hSpCas9	negative selection	4382339
55302788	55302810	19	+	27760321	OCIAML3	viability	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.174235173092198	[515,426]	[395,437]	2	hSpCas9	negative selection	4382340
55294220	55294242	19	-	27760321	OCIAML2	viability	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	-0.42115561044753325	[462,349]	[177,329]	-5	hSpCas9	negative selection	4465799
55294387	55294409	19	-	27760321	OCIAML2	viability	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.6065783021774134	[970,884]	[1113,1179]	8	hSpCas9	negative selection	4465800
55301613	55301635	19	-	27760321	OCIAML2	viability	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	0.40969878566016077	[360,325]	[313,440]	5	hSpCas9	negative selection	4465801
55302735	55302757	19	-	27760321	OCIAML2	viability	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.33939135115178054	[1006,789]	[897,933]	4	hSpCas9	negative selection	4465802
55302788	55302810	19	+	27760321	OCIAML2	viability	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.3611463277622281	[515,426]	[463,518]	5	hSpCas9	negative selection	4465803
55294220	55294242	19	-	27760321	MV411	viability	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.1488192485852546	[462,349]	[31,689]	1	hSpCas9	negative selection	4549262
55294387	55294409	19	-	27760321	MV411	viability	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.8393788140986524	[970,884]	[1292,797]	6	hSpCas9	negative selection	4549263
55301613	55301635	19	-	27760321	MV411	viability	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	-0.012934389027120241	[360,325]	[285,131]	0	hSpCas9	negative selection	4549264
55302735	55302757	19	-	27760321	MV411	viability	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.9362362752967226	[1006,789]	[706,1757]	7	hSpCas9	negative selection	4549265
55302788	55302810	19	+	27760321	MV411	viability	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.5675249342121149	[515,426]	[277,730]	4	hSpCas9	negative selection	4549266
55294220	55294242	19	-	27760321	HL60	viability	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.18043730625345827	[462,349]	[314,434]	2	hSpCas9	negative selection	4632725
55294387	55294409	19	-	27760321	HL60	viability	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.7290922154115502	[970,884]	[1285,1223]	8	hSpCas9	negative selection	4632726
55301613	55301635	19	-	27760321	HL60	viability	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	-0.5353868313777413	[360,325]	[157,230]	-5	hSpCas9	negative selection	4632727
55302735	55302757	19	-	27760321	HL60	viability	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.8760533096961558	[1006,789]	[1425,1244]	8	hSpCas9	negative selection	4632728
55302788	55302810	19	+	27760321	HL60	viability	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.09539091020711313	[515,426]	[397,421]	1	hSpCas9	negative selection	4632729
55294220	55294242	19	-	27760321	HT1080	viability	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	1.2117015009465164	[349,272]	[337,231]	6	hSpCas9	negative selection	4716188
55294387	55294409	19	-	27760321	HT1080	viability	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.6980987004679906	[884,690]	[483,536]	4	hSpCas9	negative selection	4716189
55301613	55301635	19	-	27760321	HT1080	viability	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	0.08728813487536913	[325,254]	[79,169]	0	hSpCas9	negative selection	4716190
55302735	55302757	19	-	27760321	HT1080	viability	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	1.5540351747216672	[789,616]	[1032,592]	8	hSpCas9	negative selection	4716191
55302788	55302810	19	+	27760321	HT1080	viability	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	1.8324424798543097	[426,332]	[751,305]	8	hSpCas9	negative selection	4716192
55294220	55294242	19	-	27760321	HT29	viability after 7 days	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.2062385090122915	[349,272]	[386,470,514]	3	hSpCas9	negative selection	4799651
55294387	55294409	19	-	27760321	HT29	viability after 7 days	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.6902303434817976	[884,690]	[1632,1546,1718]	9	hSpCas9	negative selection	4799652
55301613	55301635	19	-	27760321	HT29	viability after 7 days	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	0.33338737108465305	[325,254]	[591,600,242]	5	hSpCas9	negative selection	4799653
55302735	55302757	19	-	27760321	HT29	viability after 7 days	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.5822303446201038	[789,616]	[1274,1659,1121]	8	hSpCas9	negative selection	4799654
55302788	55302810	19	+	27760321	HT29	viability after 7 days	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.6447116892496572	[426,332]	[1218,587,554]	8	hSpCas9	negative selection	4799655
55294220	55294242	19	-	27760321	HT29	viability after 25 days	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.6704159292779529	[349,272]	[585,523,589]	7	hSpCas9	negative selection	4883114
55294387	55294409	19	-	27760321	HT29	viability after 25 days	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.5136808118372405	[884,690]	[1376,1259,1203]	5	hSpCas9	negative selection	4883115
55301613	55301635	19	-	27760321	HT29	viability after 25 days	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	-0.45584316090275967	[325,254]	[259,254,205]	-4	hSpCas9	negative selection	4883116
55302735	55302757	19	-	27760321	HT29	viability after 25 days	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.29505505710638635	[789,616]	[876,866,1247]	3	hSpCas9	negative selection	4883117
55302788	55302810	19	+	27760321	HT29	viability after 25 days	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.5820268790853947	[426,332]	[719,589,632]	6	hSpCas9	negative selection	4883118
55294220	55294242	19	-	27760321	HT29	viability after 22 days	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.3324601725719055	[349,272]	[612,385,355]	3	hSpCas9	negative selection	4966577
55294387	55294409	19	-	27760321	HT29	viability after 22 days	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.19909920588002783	[884,690]	[1052,950,1133]	2	hSpCas9	negative selection	4966578
55301613	55301635	19	-	27760321	HT29	viability after 22 days	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	-0.1825295309934617	[325,254]	[291,297,297]	-2	hSpCas9	negative selection	4966579
55302735	55302757	19	-	27760321	HT29	viability after 22 days	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.0423348943001467	[789,616]	[526,734,1262]	0	hSpCas9	negative selection	4966580
55302788	55302810	19	+	27760321	HT29	viability after 22 days	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.4330622444036173	[426,332]	[391,549,844]	5	hSpCas9	negative selection	4966581
55294220	55294242	19	-	27760321	HT29	viability after 19 days	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.12719742894552674	[349,272]	[563,331,292]	1	hSpCas9	negative selection	5050040
55294387	55294409	19	-	27760321	HT29	viability after 19 days	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.23783950546205923	[884,690]	[1408,756,1057]	2	hSpCas9	negative selection	5050041
55301613	55301635	19	-	27760321	HT29	viability after 19 days	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	0.7187336628566915	[325,254]	[584,587,473]	7	hSpCas9	negative selection	5050042
55302735	55302757	19	-	27760321	HT29	viability after 19 days	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.6198108497967569	[789,616]	[1169,1174,1351]	6	hSpCas9	negative selection	5050043
55302788	55302810	19	+	27760321	HT29	viability after 19 days	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.03831366272107739	[426,332]	[694,154,511]	0	hSpCas9	negative selection	5050044
55294220	55294242	19	-	27760321	HT29	viability after 16 days	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.2814069951750787	[349,272]	[562,337,384]	3	hSpCas9	negative selection	5133503
55294387	55294409	19	-	27760321	HT29	viability after 16 days	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.4744731166634293	[884,690]	[1474,1006,1221]	5	hSpCas9	negative selection	5133504
55301613	55301635	19	-	27760321	HT29	viability after 16 days	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	-0.20441338338440052	[325,254]	[448,207,206]	-2	hSpCas9	negative selection	5133505
55302735	55302757	19	-	27760321	HT29	viability after 16 days	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.6426131157730539	[789,616]	[1321,1267,1103]	7	hSpCas9	negative selection	5133506
55302788	55302810	19	+	27760321	HT29	viability after 16 days	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.8865099071903659	[426,332]	[1023,829,524]	9	hSpCas9	negative selection	5133507
55294220	55294242	19	-	27760321	HT29	viability after 13 days	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.732526192507728	[349,272]	[581,717,506]	8	hSpCas9	negative selection	5216966
55294387	55294409	19	-	27760321	HT29	viability after 13 days	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.5898416417094414	[884,690]	[1337,1675,1128]	7	hSpCas9	negative selection	5216967
55301613	55301635	19	-	27760321	HT29	viability after 13 days	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	0.14068094189669242	[325,254]	[351,412,350]	1	hSpCas9	negative selection	5216968
55302735	55302757	19	-	27760321	HT29	viability after 13 days	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.5908397774959815	[789,616]	[1043,1244,1388]	7	hSpCas9	negative selection	5216969
55302788	55302810	19	+	27760321	HT29	viability after 13 days	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.47873311067861135	[426,332]	[517,693,629]	6	hSpCas9	negative selection	5216970
55294220	55294242	19	-	27760321	HT29	viability after 10 days	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.3321428412611781	[349,272]	[528,457,480]	4	hSpCas9	negative selection	5300429
55294387	55294409	19	-	27760321	HT29	viability after 10 days	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.4572154384577478	[884,690]	[1295,1533,1229]	6	hSpCas9	negative selection	5300430
55301613	55301635	19	-	27760321	HT29	viability after 10 days	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	0.11305304559551152	[325,254]	[532,250,388]	1	hSpCas9	negative selection	5300431
55302735	55302757	19	-	27760321	HT29	viability after 10 days	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.7441308382595717	[789,616]	[1288,1700,1430]	8	hSpCas9	negative selection	5300432
55302788	55302810	19	+	27760321	HT29	viability after 10 days	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.9949910536988988	[426,332]	[633,1073,1127]	9	hSpCas9	negative selection	5300433
55294220	55294242	19	-	27760321	MOLM13	viability	CACCTCTGGACACGCATAATGG	BRSK1	ENSG00000160469	0.10807224400331963	[462,349]	[188,292]	0	hSpCas9	negative selection	5383892
55294387	55294409	19	-	27760321	MOLM13	viability	GGGCGCCTTACCACGAGCAGGG	BRSK1	ENSG00000160469	0.7545900669482406	[970,884]	[1529,331]	5	hSpCas9	negative selection	5383893
55301613	55301635	19	-	27760321	MOLM13	viability	TTCGATCATTCCCCTCAGGAGG	BRSK1	ENSG00000160469	1.0359333761368728	[360,325]	[463,339]	7	hSpCas9	negative selection	5383894
55302735	55302757	19	-	27760321	MOLM13	viability	ATGGCTACCCGGCGGCCAGGGG	BRSK1	ENSG00000160469	0.8466574758048595	[1006,789]	[695,1083]	6	hSpCas9	negative selection	5383895
55302788	55302810	19	+	27760321	MOLM13	viability	CCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.4332399348968453	[515,426]	[153,231]	-3	hSpCas9	negative selection	5383896
55284015	55284038	19	+	27661255	K562	viability	GCCGGAGAGAAAGGACGAGGTGG	BRSK1	ENSG00000160469	0.4365425250390838	[413,421]	[468,436]	9	dCas9-KRAB	negative selection	5465563
55284018	55284041	19	+	27661255	K562	viability	GGAGAGAAAGGACGAGGTGGCGG	BRSK1	ENSG00000160469	0.06935626732700856	[654,767]	[619,572]	2	dCas9-KRAB	negative selection	5465564
55284369	55284392	19	-	27661255	K562	viability	GTCGCCCCGTCTCTCCGGTGGGG	BRSK1	ENSG00000160469	0.03517824621805721	[1070,1058]	[940,812]	1	dCas9-KRAB	negative selection	5465565
55289551	55289574	19	-	27260156	BXPC3	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.2978821613847781	[192]	[211,200,295,294]	6	hSpCas9	negative selection	5531009
55289576	55289599	19	-	27260156	BXPC3	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.0796384540784596	[674]	[710,629,768,897]	1	hSpCas9	negative selection	5531010
55302763	55302786	19	+	27260156	BXPC3	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.23527306857959834	[461]	[552,596,543,576]	5	hSpCas9	negative selection	5531011
55302787	55302810	19	+	27260156	BXPC3	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.34124247643810746	[430]	[317,364,339,406]	-6	hSpCas9	negative selection	5595293
55294379	55294402	19	-	27260156	BXPC3	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.2754931694412417	[179]	[180,115,197,121]	-6	hSpCas9	negative selection	5595294
55294376	55294399	19	+	27260156	BXPC3	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.011318200595337391	[1075]	[994,1146,1056,1370]	0	hSpCas9	negative selection	5595295
55289551	55289574	19	-	27260156	A673	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.43385583327289956	[192]	[269,365,242,369]	8	hSpCas9	negative selection	5652260
55289576	55289599	19	-	27260156	A673	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.2628717470866231	[674]	[1212,832,901,971]	6	hSpCas9	negative selection	5652261
55302763	55302786	19	+	27260156	A673	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.06912278760807791	[461]	[686,544,544,561]	1	hSpCas9	negative selection	5652262
55302787	55302810	19	+	27260156	A673	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.12819167823712602	[430]	[521,344,520,515]	-3	hSpCas9	negative selection	5716544
55294379	55294402	19	-	27260156	A673	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.8367922643020518	[179]	[150,88,112,135]	-9	hSpCas9	negative selection	5716545
55294376	55294399	19	+	27260156	A673	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.1453272895965838	[1075]	[1451,1445,1349,1469]	3	hSpCas9	negative selection	5716546
55289551	55289574	19	-	27260156	A375	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.7662252719555016	[192]	[369,406,362,393]	9	hSpCas9	negative selection	5773511
55289576	55289599	19	-	27260156	A375	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.2705308273499014	[674]	[918,1189,1130,631]	4	hSpCas9	negative selection	5773512
55302763	55302786	19	+	27260156	A375	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.5065283348060134	[461]	[680,934,729,742]	7	hSpCas9	negative selection	5773513
55302787	55302810	19	+	27260156	A375	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.22408288606907367	[430]	[300,316,485,582]	-3	hSpCas9	negative selection	5837795
55294379	55294402	19	-	27260156	A375	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.3657197598630568	[179]	[337,110,88,113]	-5	hSpCas9	negative selection	5837796
55294376	55294399	19	+	27260156	A375	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.08467194605440787	[1075]	[1387,1398,907,1606]	1	hSpCas9	negative selection	5837797
55289551	55289574	19	-	27260156	COLO741	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.6722403069742409	[192]	[319,528,327]	9	hSpCas9	negative selection	5894762
55289576	55289599	19	-	27260156	COLO741	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.2200162751697593	[674]	[1239,1122,691]	4	hSpCas9	negative selection	5894763
55302763	55302786	19	+	27260156	COLO741	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.011327143753559601	[461]	[740,506,550]	0	hSpCas9	negative selection	5894764
55302787	55302810	19	+	27260156	COLO741	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.13656239498024894	[430]	[726,550,550]	3	hSpCas9	negative selection	5959046
55294379	55294402	19	-	27260156	COLO741	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.3803664073043833	[179]	[145,146,229]	-7	hSpCas9	negative selection	5959047
55294376	55294399	19	+	27260156	COLO741	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.08569316920322967	[1075]	[1637,1536,1230]	1	hSpCas9	negative selection	5959048
55289551	55289574	19	-	27260156	CAL120	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.877643718761457	[192]	[503,550,280]	9	hSpCas9	negative selection	6016013
55289576	55289599	19	-	27260156	CAL120	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.04686350976290499	[674]	[725,1076,779]	0	hSpCas9	negative selection	6016014
55302763	55302786	19	+	27260156	CAL120	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.47640537344201866	[461]	[1109,709,628]	7	hSpCas9	negative selection	6016015
55302787	55302810	19	+	27260156	CAL120	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.23695359426773427	[430]	[263,541,528]	-3	hSpCas9	negative selection	6080297
55294379	55294402	19	-	27260156	CAL120	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.6815005686261233	[179]	[181,142,100]	-7	hSpCas9	negative selection	6080298
55294376	55294399	19	+	27260156	CAL120	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.01039672070268649	[1075]	[1297,1348,1389]	0	hSpCas9	negative selection	6080299
55289551	55289574	19	-	27260156	CADOES1	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.5595777485987485	[192]	[202,229,367,256]	8	hSpCas9	negative selection	6137264
55289576	55289599	19	-	27260156	CADOES1	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.12586396671384237	[674]	[684,659,684,710]	2	hSpCas9	negative selection	6137265
55302763	55302786	19	+	27260156	CADOES1	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	-0.047257549241702765	[461]	[432,478,321,429]	-1	hSpCas9	negative selection	6137266
55302787	55302810	19	+	27260156	CADOES1	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.2801896416428846	[430]	[479,247,257,333]	-5	hSpCas9	negative selection	6201548
55294379	55294402	19	-	27260156	CADOES1	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.3912832245598683	[179]	[111,104,179,112]	-6	hSpCas9	negative selection	6201549
55294376	55294399	19	+	27260156	CADOES1	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.02265281523725937	[1075]	[1062,949,950,975]	0	hSpCas9	negative selection	6201550
55289551	55289574	19	-	27260156	EWS502	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.5776327221151251	[192]	[226,309,331,363]	8	hSpCas9	negative selection	6258515
55289576	55289599	19	-	27260156	EWS502	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.17495378358929525	[674]	[681,774,694,1109]	3	hSpCas9	negative selection	6258516
55302763	55302786	19	+	27260156	EWS502	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.3718163385240602	[461]	[489,711,606,742]	6	hSpCas9	negative selection	6258517
55302787	55302810	19	+	27260156	EWS502	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.2028267328336757	[430]	[307,390,283,627]	-4	hSpCas9	negative selection	6322799
55294379	55294402	19	-	27260156	EWS502	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.004859384680704348	[179]	[127,149,221,274]	0	hSpCas9	negative selection	6322800
55294376	55294399	19	+	27260156	EWS502	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.3073208162941019	[1075]	[1027,1464,1649,1549]	5	hSpCas9	negative selection	6322801
55289551	55289574	19	-	27260156	EW8	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	1.026964296981943	[192]	[400,292,294,297]	9	hSpCas9	negative selection	6379766
55289576	55289599	19	-	27260156	EW8	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.36357673301990623	[674]	[775,661,739,636]	6	hSpCas9	negative selection	6379767
55302763	55302786	19	+	27260156	EW8	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.3673504043744016	[461]	[505,337,602,464]	6	hSpCas9	negative selection	6379768
55302787	55302810	19	+	27260156	EW8	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.17410418158869106	[430]	[376,249,204,429]	-3	hSpCas9	negative selection	6444050
55294379	55294402	19	-	27260156	EW8	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.24136047141583372	[179]	[144,68,118,162]	-4	hSpCas9	negative selection	6444051
55294376	55294399	19	+	27260156	EW8	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.15663482634317827	[1075]	[1154,945,765,1072]	3	hSpCas9	negative selection	6444052
55289551	55289574	19	-	27260156	CORL105	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.12605096519791736	[192]	[250,227,279,232]	2	hSpCas9	negative selection	6501017
55289576	55289599	19	-	27260156	CORL105	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.5404267628647065	[674]	[1165,1081,1252,1113]	8	hSpCas9	negative selection	6501018
55302763	55302786	19	+	27260156	CORL105	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.31895718826452296	[461]	[679,674,757,598]	6	hSpCas9	negative selection	6501019
55302787	55302810	19	+	27260156	CORL105	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.05703602814791081	[430]	[672,426,526,479]	1	hSpCas9	negative selection	6565301
55294379	55294402	19	-	27260156	CORL105	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.36114124871537023	[179]	[144,165,173,171]	-6	hSpCas9	negative selection	6565302
55294376	55294399	19	+	27260156	CORL105	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.09512389910632302	[1075]	[1365,1211,1767,1105]	1	hSpCas9	negative selection	6565303
55289551	55289574	19	-	27260156	HS294T	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	1.089040390113655	[192]	[133,252,130,106]	9	hSpCas9	negative selection	6622268
55289576	55289599	19	-	27260156	HS294T	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.46869066489540967	[674]	[346,239,270,636]	6	hSpCas9	negative selection	6622269
55302763	55302786	19	+	27260156	HS294T	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.3862210848451307	[461]	[178,377,169,200]	5	hSpCas9	negative selection	6622270
55302787	55302810	19	+	27260156	HS294T	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.18029111528334307	[430]	[107,192,106,188]	-3	hSpCas9	negative selection	6686552
55294379	55294402	19	-	27260156	HS294T	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.1263090231040187	[179]	[58,63,64,67]	-2	hSpCas9	negative selection	6686553
55294376	55294399	19	+	27260156	HS294T	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.1849062099358898	[1075]	[340,438,581,555]	2	hSpCas9	negative selection	6686554
55289551	55289574	19	-	27260156	HCC44	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.4682492014589742	[192]	[435,270,246,259]	7	hSpCas9	negative selection	6743519
55289576	55289599	19	-	27260156	HCC44	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.14025091448817428	[674]	[957,737,937,768]	2	hSpCas9	negative selection	6743520
55302763	55302786	19	+	27260156	HCC44	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	-0.06779495856142982	[461]	[561,277,522,662]	-1	hSpCas9	negative selection	6743521
55302787	55302810	19	+	27260156	HCC44	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.3858073982012464	[430]	[894,538,460,653]	6	hSpCas9	negative selection	6807803
55294379	55294402	19	-	27260156	HCC44	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.12661111450051998	[179]	[181,122,308,160]	-2	hSpCas9	negative selection	6807804
55294376	55294399	19	+	27260156	HCC44	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.33749340281511686	[1075]	[1873,1113,1733,1540]	5	hSpCas9	negative selection	6807805
55289551	55289574	19	-	27260156	G402	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.30459671307882497	[192]	[291,302,421,152]	4	hSpCas9	negative selection	6864770
55289576	55289599	19	-	27260156	G402	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.1684626016799181	[674]	[1184,852,699,990]	2	hSpCas9	negative selection	6864771
55302763	55302786	19	+	27260156	G402	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.2534443590069442	[461]	[858,572,885,401]	3	hSpCas9	negative selection	6864772
55302787	55302810	19	+	27260156	G402	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.4718592760078779	[430]	[351,400,408,351]	-5	hSpCas9	negative selection	6929054
55294379	55294402	19	-	27260156	G402	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.6505997721772516	[179]	[154,166,103,136]	-7	hSpCas9	negative selection	6929055
55294376	55294399	19	+	27260156	G402	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.5854532867350963	[1075]	[1509,1864,1562,2819]	7	hSpCas9	negative selection	6929056
55289551	55289574	19	-	27260156	L33	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.25702035802979895	[192]	[225,83,168,222]	5	hSpCas9	negative selection	6986021
55289576	55289599	19	-	27260156	L33	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.217220966994513	[674]	[819,260,519,852]	5	hSpCas9	negative selection	6986022
55302763	55302786	19	+	27260156	L33	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	-0.02665171393948134	[461]	[483,166,309,428]	0	hSpCas9	negative selection	6986023
55302787	55302810	19	+	27260156	L33	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.08100529192071841	[430]	[341,180,322,334]	-2	hSpCas9	negative selection	7050305
55294379	55294402	19	-	27260156	L33	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.17247286206256374	[179]	[180,62,86,164]	-4	hSpCas9	negative selection	7050306
55294376	55294399	19	+	27260156	L33	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.0836007537952026	[1075]	[1041,428,650,936]	-2	hSpCas9	negative selection	7050307
55289551	55289574	19	-	27260156	K562	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.8106801055315409	[192]	[300,487,202,226]	8	hSpCas9	negative selection	7107272
55289576	55289599	19	-	27260156	K562	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.2839248547214085	[674]	[871,772,722,577]	3	hSpCas9	negative selection	7107273
55302763	55302786	19	+	27260156	K562	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.12249095981310966	[461]	[521,702,234,353]	1	hSpCas9	negative selection	7107274
55302787	55302810	19	+	27260156	K562	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-1.0095169434103235	[430]	[303,194,138,136]	-8	hSpCas9	negative selection	7171556
55294379	55294402	19	-	27260156	K562	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.716899044959415	[179]	[10,51,247,70]	-7	hSpCas9	negative selection	7171557
55294376	55294399	19	+	27260156	K562	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.22025821942452084	[1075]	[872,869,745,795]	-3	hSpCas9	negative selection	7171558
55289551	55289574	19	-	27260156	HT29	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.5319745674851339	[192]	[359,268,300,410]	8	hSpCas9	negative selection	7228523
55289576	55289599	19	-	27260156	HT29	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.07588396879635018	[674]	[900,773,1068,721]	1	hSpCas9	negative selection	7228524
55302763	55302786	19	+	27260156	HT29	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.18158742378617143	[461]	[622,862,613,480]	3	hSpCas9	negative selection	7228525
55302787	55302810	19	+	27260156	HT29	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.04814239002684699	[430]	[528,447,545,497]	-1	hSpCas9	negative selection	7292807
55294379	55294402	19	-	27260156	HT29	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.32458573247276123	[179]	[184,191,175,149]	-6	hSpCas9	negative selection	7292808
55294376	55294399	19	+	27260156	HT29	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.0749850979587714	[1075]	[1177,1435,1322,1055]	-1	hSpCas9	negative selection	7292809
55289551	55289574	19	-	27260156	MHHES1	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.5479852261448505	[192]	[382,277,331,282]	8	hSpCas9	negative selection	7349774
55289576	55289599	19	-	27260156	MHHES1	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.33561236704749786	[674]	[1036,1078,915,833]	6	hSpCas9	negative selection	7349775
55302763	55302786	19	+	27260156	MHHES1	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.21385713751726093	[461]	[744,721,491,494]	4	hSpCas9	negative selection	7349776
55302787	55302810	19	+	27260156	MHHES1	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.10911339306717044	[430]	[417,596,589,481]	2	hSpCas9	negative selection	7414058
55294379	55294402	19	-	27260156	MHHES1	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.15293565089621164	[179]	[295,191,113,145]	-3	hSpCas9	negative selection	7414059
55294376	55294399	19	+	27260156	MHHES1	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.053288858884783075	[1075]	[951,1320,1329,1057]	-1	hSpCas9	negative selection	7414060
55289551	55289574	19	-	27260156	MEWO	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.626902025843946	[192]	[404,254,200]	9	hSpCas9	negative selection	7471025
55289576	55289599	19	-	27260156	MEWO	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	-0.13114884405204058	[674]	[618,569,548]	-3	hSpCas9	negative selection	7471026
55302763	55302786	19	+	27260156	MEWO	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.12262076871654053	[461]	[535,529,357]	2	hSpCas9	negative selection	7471027
55302787	55302810	19	+	27260156	MEWO	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.1212833846153639	[430]	[390,368,355]	-3	hSpCas9	negative selection	7535309
55294379	55294402	19	-	27260156	MEWO	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.14914159448730557	[179]	[188,99,173]	-3	hSpCas9	negative selection	7535310
55294376	55294399	19	+	27260156	MEWO	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.1541357985434919	[1075]	[1610,987,856]	3	hSpCas9	negative selection	7535311
55289551	55289574	19	-	27260156	LNCAPCLONEFGC	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.8947274182492151	[192]	[323,381,410,191]	9	hSpCas9	negative selection	7592276
55289576	55289599	19	-	27260156	LNCAPCLONEFGC	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.3401011164074641	[674]	[750,763,924,678]	5	hSpCas9	negative selection	7592277
55302763	55302786	19	+	27260156	LNCAPCLONEFGC	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.166151679678741	[461]	[480,366,505,535]	2	hSpCas9	negative selection	7592278
55302787	55302810	19	+	27260156	LNCAPCLONEFGC	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.10889675284083618	[430]	[323,277,454,410]	-2	hSpCas9	negative selection	7656560
55294379	55294402	19	-	27260156	LNCAPCLONEFGC	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.328606140599065	[179]	[99,131,151,138]	-5	hSpCas9	negative selection	7656561
55294376	55294399	19	+	27260156	LNCAPCLONEFGC	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.04653386882369959	[1075]	[883,1003,986,902]	0	hSpCas9	negative selection	7656562
55289551	55289574	19	-	27260156	PANC0327	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.7503926885124362	[192]	[399,230,227,310]	9	hSpCas9	negative selection	7713527
55289576	55289599	19	-	27260156	PANC0327	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.5400706426610306	[674]	[1152,489,704,1210]	7	hSpCas9	negative selection	7713528
55302763	55302786	19	+	27260156	PANC0327	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.5258926231107264	[461]	[728,618,493,528]	7	hSpCas9	negative selection	7713529
55302787	55302810	19	+	27260156	PANC0327	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.26016036727689823	[430]	[642,758,199,207]	4	hSpCas9	negative selection	7777811
55294379	55294402	19	-	27260156	PANC0327	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.21081395850668572	[179]	[219,222,110,183]	3	hSpCas9	negative selection	7777812
55294376	55294399	19	+	27260156	PANC0327	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.08803184640539596	[1075]	[911,929,985,765]	-1	hSpCas9	negative selection	7777813
55289551	55289574	19	-	27260156	NCIH2009	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.6551428704968008	[192]	[316,254,682]	8	hSpCas9	negative selection	7834778
55289576	55289599	19	-	27260156	NCIH2009	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.07506027496379364	[674]	[1135,983,886]	1	hSpCas9	negative selection	7834779
55302763	55302786	19	+	27260156	NCIH2009	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.5663531402618743	[461]	[1101,885,907]	7	hSpCas9	negative selection	7834780
55302787	55302810	19	+	27260156	NCIH2009	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.40417606217593066	[430]	[771,926,682]	5	hSpCas9	negative selection	7899062
55294379	55294402	19	-	27260156	NCIH2009	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.03680207556541881	[179]	[368,218,171]	0	hSpCas9	negative selection	7899063
55294376	55294399	19	+	27260156	NCIH2009	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.10961341987119777	[1075]	[1819,1589,1492]	1	hSpCas9	negative selection	7899064
55289551	55289574	19	-	27260156	NCIH1373	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.4677055110359679	[192]	[107,673,116,58]	4	hSpCas9	negative selection	7956029
55289576	55289599	19	-	27260156	NCIH1373	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.6818644543408979	[674]	[1818,1116,944,280]	6	hSpCas9	negative selection	7956030
55302763	55302786	19	+	27260156	NCIH1373	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.5945000798655246	[461]	[1090,345,706,287]	6	hSpCas9	negative selection	7956031
55302787	55302810	19	+	27260156	NCIH1373	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.06449618197322128	[430]	[336,242,430,226]	0	hSpCas9	negative selection	8020313
55294379	55294402	19	-	27260156	NCIH1373	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.026009091483708113	[179]	[589,111,99,21]	0	hSpCas9	negative selection	8020314
55294376	55294399	19	+	27260156	NCIH1373	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.2867754604206847	[1075]	[933,1068,754,312]	-3	hSpCas9	negative selection	8020315
55289551	55289574	19	-	27260156	PATU8902	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.49488063581866937	[192]	[634,238,198,495]	5	hSpCas9	negative selection	8077280
55289576	55289599	19	-	27260156	PATU8902	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.7894913233082593	[674]	[2007,1373,1552,1555]	8	hSpCas9	negative selection	8077281
55302763	55302786	19	+	27260156	PATU8902	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.531454005680846	[461]	[1096,1348,750,510]	5	hSpCas9	negative selection	8077282
55302787	55302810	19	+	27260156	PATU8902	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.31059768502809504	[430]	[604,362,312,721]	-3	hSpCas9	negative selection	8141564
55294379	55294402	19	-	27260156	PATU8902	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.406093439468485	[179]	[47,118,338,214]	-4	hSpCas9	negative selection	8141565
55294376	55294399	19	+	27260156	PATU8902	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.14465990968464526	[1075]	[1688,1704,1609,1615]	1	hSpCas9	negative selection	8141566
55289551	55289574	19	-	27260156	PANC1	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.5262035530571192	[192]	[152,269,332,208]	8	hSpCas9	negative selection	8198531
55289576	55289599	19	-	27260156	PANC1	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.11506090150616333	[674]	[587,840,794,366]	1	hSpCas9	negative selection	8198532
55302763	55302786	19	+	27260156	PANC1	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.12291908683616351	[461]	[397,603,392,371]	2	hSpCas9	negative selection	8198533
55302787	55302810	19	+	27260156	PANC1	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.04145044115557893	[430]	[397,427,456,191]	0	hSpCas9	negative selection	8262815
55294379	55294402	19	-	27260156	PANC1	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.6990777306714047	[179]	[102,63,104,99]	-7	hSpCas9	negative selection	8262816
55294376	55294399	19	+	27260156	PANC1	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.024238440974450715	[1075]	[1271,898,1049,569]	0	hSpCas9	negative selection	8262817
55289551	55289574	19	-	27260156	PANC0813	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.637828815011516	[192]	[526,240,264,390]	8	hSpCas9	negative selection	8319782
55289576	55289599	19	-	27260156	PANC0813	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.4909283308302582	[674]	[1502,1066,1118,818]	7	hSpCas9	negative selection	8319783
55302763	55302786	19	+	27260156	PANC0813	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.1474875321867215	[461]	[689,618,601,505]	2	hSpCas9	negative selection	8319784
55302787	55302810	19	+	27260156	PANC0813	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.25069912895946483	[430]	[646,299,356,417]	-4	hSpCas9	negative selection	8384066
55294379	55294402	19	-	27260156	PANC0813	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.22019275199380406	[179]	[300,315,207,168]	3	hSpCas9	negative selection	8384067
55294376	55294399	19	+	27260156	PANC0813	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.0666741807048088	[1075]	[1526,1161,1669,973]	1	hSpCas9	negative selection	8384068
55289551	55289574	19	-	27260156	RDES	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.76243255591535	[192]	[269,366,439,456]	9	hSpCas9	negative selection	8441033
55289576	55289599	19	-	27260156	RDES	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.36855329101867473	[674]	[798,1008,1077,1162]	6	hSpCas9	negative selection	8441034
55302763	55302786	19	+	27260156	RDES	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.21952153754821108	[461]	[575,536,628,749]	3	hSpCas9	negative selection	8441035
55302787	55302810	19	+	27260156	RDES	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.2212339338011397	[430]	[324,407,408,594]	-4	hSpCas9	negative selection	8505317
55294379	55294402	19	-	27260156	RDES	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.6097883554691326	[179]	[104,101,196,148]	-8	hSpCas9	negative selection	8505318
55294376	55294399	19	+	27260156	RDES	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.03252244782687885	[1075]	[1007,1191,1210,1476]	0	hSpCas9	negative selection	8505319
55289551	55289574	19	-	27260156	PC3	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.34288166856899593	[192]	[151,384,295,166]	7	hSpCas9	negative selection	8562284
55289576	55289599	19	-	27260156	PC3	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.005495295641496645	[674]	[425,595,1194,737]	0	hSpCas9	negative selection	8562285
55302763	55302786	19	+	27260156	PC3	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.08095463718237503	[461]	[326,411,805,554]	1	hSpCas9	negative selection	8562286
55302787	55302810	19	+	27260156	PC3	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	0.04140061559709747	[430]	[443,247,671,438]	0	hSpCas9	negative selection	8626568
55294379	55294402	19	-	27260156	PC3	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.16219915404352125	[179]	[68,275,178,144]	-4	hSpCas9	negative selection	8626569
55294376	55294399	19	+	27260156	PC3	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.20153463000610228	[1075]	[747,1254,1550,1612]	4	hSpCas9	negative selection	8626570
55289551	55289574	19	-	27260156	PATU8988T	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.8050039911485543	[192]	[331,349,316,304]	9	hSpCas9	negative selection	8683535
55289576	55289599	19	-	27260156	PATU8988T	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	-0.20916885295005844	[674]	[562,628,454,621]	-4	hSpCas9	negative selection	8683536
55302763	55302786	19	+	27260156	PATU8988T	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.08017755259786805	[461]	[494,393,613,366]	1	hSpCas9	negative selection	8683537
55302787	55302810	19	+	27260156	PATU8988T	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.30534869787694646	[430]	[315,280,327,424]	-5	hSpCas9	negative selection	8747819
55294379	55294402	19	-	27260156	PATU8988T	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.4952607595819829	[179]	[54,206,110,128]	-7	hSpCas9	negative selection	8747820
55294376	55294399	19	+	27260156	PATU8988T	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.22196244574140211	[1075]	[750,900,862,1065]	-4	hSpCas9	negative selection	8747821
55289551	55289574	19	-	27260156	T47D	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.45005651563368243	[192]	[308,363,275,273]	8	hSpCas9	negative selection	8804786
55289576	55289599	19	-	27260156	T47D	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.11470467659744688	[674]	[739,1032,816,797]	2	hSpCas9	negative selection	8804787
55302763	55302786	19	+	27260156	T47D	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.32710694088937853	[461]	[675,744,673,596]	7	hSpCas9	negative selection	8804788
55302787	55302810	19	+	27260156	T47D	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.14067387408940796	[430]	[404,352,449,627]	-3	hSpCas9	negative selection	8869070
55294379	55294402	19	-	27260156	T47D	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.2859366745669696	[179]	[159,149,211,166]	-6	hSpCas9	negative selection	8869071
55294376	55294399	19	+	27260156	T47D	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.026812910635776177	[1075]	[1330,1221,1234,1326]	0	hSpCas9	negative selection	8869072
55289551	55289574	19	-	27260156	SU8686	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.36430731319556464	[192]	[276,202,258,246]	6	hSpCas9	negative selection	8926037
55289576	55289599	19	-	27260156	SU8686	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.16975571475270534	[674]	[697,695,642,1022]	3	hSpCas9	negative selection	8926038
55302763	55302786	19	+	27260156	SU8686	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.184636910770341	[461]	[444,504,545,607]	3	hSpCas9	negative selection	8926039
55302787	55302810	19	+	27260156	SU8686	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.05426266458446495	[430]	[384,345,455,479]	-1	hSpCas9	negative selection	8990321
55294379	55294402	19	-	27260156	SU8686	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.09872036105958859	[179]	[129,215,216,206]	1	hSpCas9	negative selection	8990322
55294376	55294399	19	+	27260156	SU8686	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.07048680550193498	[1075]	[934,1015,1178,1428]	1	hSpCas9	negative selection	8990323
55289551	55289574	19	-	27260156	SKES1	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.6183158481720142	[192]	[228,353,362,236]	9	hSpCas9	negative selection	9047288
55289576	55289599	19	-	27260156	SKES1	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.30511631572698794	[674]	[871,1154,616,733]	6	hSpCas9	negative selection	9047289
55302763	55302786	19	+	27260156	SKES1	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.02500471666084404	[461]	[527,456,506,393]	0	hSpCas9	negative selection	9047290
55302787	55302810	19	+	27260156	SKES1	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.011712189653022911	[430]	[464,450,415,382]	0	hSpCas9	negative selection	9111572
55294379	55294402	19	-	27260156	SKES1	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.17572426718121825	[179]	[115,185,187,142]	-4	hSpCas9	negative selection	9111573
55294376	55294399	19	+	27260156	SKES1	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.18653628277315226	[1075]	[1385,1411,1277,882]	4	hSpCas9	negative selection	9111574
55289551	55289574	19	-	27260156	TOV112D	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.4251922307728515	[192]	[287,264,173,312]	7	hSpCas9	negative selection	9168539
55289576	55289599	19	-	27260156	TOV112D	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	-0.17477234260886826	[674]	[568,778,508,579]	-3	hSpCas9	negative selection	9168540
55302763	55302786	19	+	27260156	TOV112D	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	-0.05198713449069882	[461]	[364,427,560,419]	-1	hSpCas9	negative selection	9168541
55302787	55302810	19	+	27260156	TOV112D	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.1659421823843436	[430]	[646,413,313,197]	-3	hSpCas9	negative selection	9232823
55294379	55294402	19	-	27260156	TOV112D	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.24327925307062603	[179]	[165,81,162,180]	-5	hSpCas9	negative selection	9232824
55294376	55294399	19	+	27260156	TOV112D	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	0.24718678102155645	[1075]	[1106,2298,821,1126]	5	hSpCas9	negative selection	9232825
55289551	55289574	19	-	27260156	TC71	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.42783999387519134	[192]	[268,290,150,414]	8	hSpCas9	negative selection	9289790
55289576	55289599	19	-	27260156	TC71	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.1731678934115829	[674]	[787,877,752,848]	4	hSpCas9	negative selection	9289791
55302763	55302786	19	+	27260156	TC71	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	-0.033534413888230696	[461]	[505,500,426,503]	-1	hSpCas9	negative selection	9289792
55302787	55302810	19	+	27260156	TC71	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.1349966190445953	[430]	[403,366,419,496]	-4	hSpCas9	negative selection	9354074
55294379	55294402	19	-	27260156	TC71	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.1678280917031889	[179]	[246,114,161,160]	-4	hSpCas9	negative selection	9354075
55294376	55294399	19	+	27260156	TC71	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.042194482560537816	[1075]	[1077,1135,1102,1167]	-1	hSpCas9	negative selection	9354076
55289551	55289574	19	-	27260156	TC32	viability	GAAGAACTTTCGGGCCTCCTTGG	BRSK1	ENSG00000160469	0.5236983364312235	[192]	[235,105,387,390]	8	hSpCas9	negative selection	9411041
55289576	55289599	19	-	27260156	TC32	viability	AGTCCAGCGCAGACACAATCTGG	BRSK1	ENSG00000160469	0.19366731649333624	[674]	[726,371,1074,891]	3	hSpCas9	negative selection	9411042
55302763	55302786	19	+	27260156	TC32	viability	CCTGCCATCCAACGGAGAGCTGG	BRSK1	ENSG00000160469	0.38946556627820395	[461]	[556,304,724,797]	6	hSpCas9	negative selection	9411043
55302787	55302810	19	+	27260156	TC32	viability	CCCCGACGTCCTAGAGAGCATGG	BRSK1	ENSG00000160469	-0.20301239214145067	[430]	[385,200,480,396]	-4	hSpCas9	negative selection	9475325
55294379	55294402	19	-	27260156	TC32	viability	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.3685170297480824	[179]	[151,78,220,94]	-6	hSpCas9	negative selection	9475326
55294376	55294399	19	+	27260156	TC32	viability	CATCCTCTTCGCCCTGCTCGTGG	BRSK1	ENSG00000160469	-0.03037337170760246	[1075]	[1071,615,1139,1245]	0	hSpCas9	negative selection	9475327
55287026	55287049	19	+	27869803	HPAFII	viability after 27 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	1.2750633074671764	[233]	[474,149,NaN]	9	hSpCas9	negative selection	9569900
55289483	55289506	19	-	27869803	HPAFII	viability after 27 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.3166357049541666	[735]	[608,375,NaN]	2	hSpCas9	negative selection	9569901
55294113	55294136	19	-	27869803	HPAFII	viability after 27 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	1.1372811038288648	[85]	[195,18,NaN]	8	hSpCas9	negative selection	9569902
55294379	55294402	19	-	27869803	HPAFII	viability after 27 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.4894388040840111	[411]	[182,404,NaN]	4	hSpCas9	negative selection	9569903
55301586	55301609	19	-	27869803	HPAFII	viability after 27 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.4462981145167464	[157]	[134,94,NaN]	3	hSpCas9	negative selection	9569904
55302118	55302141	19	+	27869803	HPAFII	viability after 27 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-1.4318039874112638	[563]	[164,63,NaN]	-7	hSpCas9	negative selection	9569905
55287026	55287049	19	+	27869803	HPAFII	viability after 15 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	1.0184542440728688	[233]	[1019,191,NaN]	9	hSpCas9	negative selection	9652349
55289483	55289506	19	-	27869803	HPAFII	viability after 15 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	-0.1864580383136174	[735]	[1225,364,NaN]	-2	hSpCas9	negative selection	9652350
55294113	55294136	19	-	27869803	HPAFII	viability after 15 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	1.346581578583941	[85]	[403,129,NaN]	9	hSpCas9	negative selection	9652351
55294379	55294402	19	-	27869803	HPAFII	viability after 15 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.04132790962270638	[411]	[441,422,NaN]	0	hSpCas9	negative selection	9652352
55301586	55301609	19	-	27869803	HPAFII	viability after 15 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.5336918430612487	[157]	[259,236,NaN]	6	hSpCas9	negative selection	9652353
55302118	55302141	19	+	27869803	HPAFII	viability after 15 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.7844561270420526	[563]	[473,275,NaN]	-7	hSpCas9	negative selection	9652354
55287026	55287049	19	+	27869803	ASPC1	viability after 36 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	0.11922265659034308	[576]	[363,284,61]	1	hSpCas9	negative selection	9734798
55289483	55289506	19	-	27869803	ASPC1	viability after 36 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.5713190369184808	[1600]	[1155,831,591]	5	hSpCas9	negative selection	9734799
55294113	55294136	19	-	27869803	ASPC1	viability after 36 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	2.26375410423294	[222]	[201,939,40]	9	hSpCas9	negative selection	9734800
55294379	55294402	19	-	27869803	ASPC1	viability after 36 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	-0.028080607499815724	[836]	[178,414,256]	0	hSpCas9	negative selection	9734801
55301586	55301609	19	-	27869803	ASPC1	viability after 36 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.47979529346551314	[441]	[122,492,56]	5	hSpCas9	negative selection	9734802
55302118	55302141	19	+	27869803	ASPC1	viability after 36 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	0.3643663574882432	[1541]	[481,1155,465]	3	hSpCas9	negative selection	9734803
55287026	55287049	19	+	27869803	PATU8988S	viability after 35 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	1.2677936465708388	[487]	[586,358,NaN]	9	hSpCas9	negative selection	9817247
55289483	55289506	19	-	27869803	PATU8988S	viability after 35 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.05708746689391608	[1460]	[685,537,NaN]	0	hSpCas9	negative selection	9817248
55294113	55294136	19	-	27869803	PATU8988S	viability after 35 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	-3.4839183305223265	[207]	[1,12,NaN]	-9	hSpCas9	negative selection	9817249
55294379	55294402	19	-	27869803	PATU8988S	viability after 35 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.15717135905108315	[589]	[252,276,NaN]	1	hSpCas9	negative selection	9817250
55301586	55301609	19	-	27869803	PATU8988S	viability after 35 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.1682345294670738	[409]	[125,167,NaN]	-2	hSpCas9	negative selection	9817251
55302118	55302141	19	+	27869803	PATU8988S	viability after 35 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.8429594199602612	[1473]	[313,347,NaN]	-7	hSpCas9	negative selection	9817252
55287026	55287049	19	+	27869803	PATU8988S	viability after 31 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	1.0905437326488867	[487]	[321,531,NaN]	9	hSpCas9	negative selection	9899696
55289483	55289506	19	-	27869803	PATU8988S	viability after 31 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.2104868209851447	[1460]	[637,719,NaN]	2	hSpCas9	negative selection	9899697
55294113	55294136	19	-	27869803	PATU8988S	viability after 31 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	-1.1476422581980916	[207]	[14,65,NaN]	-8	hSpCas9	negative selection	9899698
55294379	55294402	19	-	27869803	PATU8988S	viability after 31 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.1845021037282074	[589]	[236,305,NaN]	2	hSpCas9	negative selection	9899699
55301586	55301609	19	-	27869803	PATU8988S	viability after 31 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	-0.24622002236032464	[409]	[110,171,NaN]	-3	hSpCas9	negative selection	9899700
55302118	55302141	19	+	27869803	PATU8988S	viability after 31 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.7302102656057599	[1473]	[275,453,NaN]	-7	hSpCas9	negative selection	9899701
55287026	55287049	19	+	27869803	HPAFII	viability after 35 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	1.1140607949056514	[233]	[262,248,NaN]	7	hSpCas9	negative selection	9982145
55289483	55289506	19	-	27869803	HPAFII	viability after 35 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.15055279268370114	[735]	[398,429,NaN]	0	hSpCas9	negative selection	9982146
55294113	55294136	19	-	27869803	HPAFII	viability after 35 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	0.8547602505557104	[85]	[137,11,NaN]	5	hSpCas9	negative selection	9982147
55294379	55294402	19	-	27869803	HPAFII	viability after 35 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.7532689974592818	[411]	[201,519,NaN]	5	hSpCas9	negative selection	9982148
55301586	55301609	19	-	27869803	HPAFII	viability after 35 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.8534110582861691	[157]	[120,170,NaN]	5	hSpCas9	negative selection	9982149
55302118	55302141	19	+	27869803	HPAFII	viability after 35 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.7389434968811732	[563]	[211,124,NaN]	-4	hSpCas9	negative selection	9982150
55287026	55287049	19	+	27869803	HPAFII	viability after 31 days	CCACTGCATCACGGGTCAGAAGG	BRSK1	ENSG00000160469	1.2965452199983716	[233]	[357,283,NaN]	8	hSpCas9	negative selection	10064594
55289483	55289506	19	-	27869803	HPAFII	viability after 31 days	CCGAGACGTGCTCCAGAACCAGG	BRSK1	ENSG00000160469	0.3234908261692411	[735]	[569,458,NaN]	2	hSpCas9	negative selection	10064595
55294113	55294136	19	-	27869803	HPAFII	viability after 31 days	ACCCGCAGCTGGTCTCCAGGAGG	BRSK1	ENSG00000160469	1.441630320307552	[85]	[244,6,NaN]	9	hSpCas9	negative selection	10064596
55294379	55294402	19	-	27869803	HPAFII	viability after 31 days	TTACCACGAGCAGGGCGAAGAGG	BRSK1	ENSG00000160469	0.7447370064438333	[411]	[229,558,NaN]	5	hSpCas9	negative selection	10064597
55301586	55301609	19	-	27869803	HPAFII	viability after 31 days	GGCAATCTGGAGGAATGAAGTGG	BRSK1	ENSG00000160469	0.19553540058186647	[157]	[68,136,NaN]	1	hSpCas9	negative selection	10064598
55302118	55302141	19	+	27869803	HPAFII	viability after 31 days	CGACTCACCACCCTCACAGCTGG	BRSK1	ENSG00000160469	-0.7813866071734075	[563]	[209,155,NaN]	-5	hSpCas9	negative selection	10064599
55287230	55287253	19	-	28162770	P31FUJ	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.8355349253487752	[133]	[280]	8	hSpCas9	negative selection	10119283
55306335	55306358	19	+	28162770	P31FUJ	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	0.2878010505103994	[190]	[273]	3	hSpCas9	negative selection	10119284
55289534	55289557	19	+	28162770	P31FUJ	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-0.43633559849951065	[189]	[164]	-4	hSpCas9	negative selection	10119285
55289573	55289596	19	-	28162770	P31FUJ	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	0.16260648811553258	[110]	[145]	1	hSpCas9	negative selection	10119286
55304070	55304093	19	-	28162770	P31FUJ	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.1921602199170327	[279]	[287]	-2	hSpCas9	negative selection	10119287
55304584	55304607	19	+	28162770	P31FUJ	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	0.09734639727795225	[69]	[87]	1	hSpCas9	negative selection	10119288
55304685	55304708	19	-	28162770	P31FUJ	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-1.4333351917870873	[392]	[170]	-7	hSpCas9	negative selection	10119289
55304843	55304866	19	-	28162770	P31FUJ	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	0.08768965835746467	[401]	[501]	0	hSpCas9	negative selection	10119290
55306297	55306320	19	+	28162770	P31FUJ	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	-0.10469737866669332	[279]	[305]	-1	hSpCas9	negative selection	10119291
55306322	55306345	19	-	28162770	P31FUJ	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.6428069333484311	[229]	[421]	7	hSpCas9	negative selection	10119292
55287230	55287253	19	-	28162770	TF1	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	NaN	[NaN]	[98]	1	hSpCas9	negative selection	10288649
55306335	55306358	19	+	28162770	TF1	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	NaN	[NaN]	[108]	1	hSpCas9	negative selection	10288650
55289534	55289557	19	+	28162770	TF1	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10288651
55289573	55289596	19	-	28162770	TF1	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	NaN	[NaN]	[72]	1	hSpCas9	negative selection	10288652
55304070	55304093	19	-	28162770	TF1	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10288653
55304584	55304607	19	+	28162770	TF1	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10288654
55304685	55304708	19	-	28162770	TF1	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10288655
55304843	55304866	19	-	28162770	TF1	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	NaN	[NaN]	[278]	1	hSpCas9	negative selection	10288656
55306297	55306320	19	+	28162770	TF1	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	NaN	[NaN]	[265]	1	hSpCas9	negative selection	10288657
55306322	55306345	19	-	28162770	TF1	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10288658
55287230	55287253	19	-	28162770	SKM1	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	-0.440131062678361	[65]	[85]	-4	hSpCas9	negative selection	10458015
55306335	55306358	19	+	28162770	SKM1	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	0.04589476597064929	[39]	[72]	0	hSpCas9	negative selection	10458016
55289534	55289557	19	+	28162770	SKM1	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-0.4683647434073049	[53]	[68]	-4	hSpCas9	negative selection	10458017
55289573	55289596	19	-	28162770	SKM1	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.01994107563391445	[38]	[67]	0	hSpCas9	negative selection	10458018
55304070	55304093	19	-	28162770	SKM1	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.0163797431888566	[118]	[207]	0	hSpCas9	negative selection	10458019
55304584	55304607	19	+	28162770	SKM1	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	0.27421361723729754	[28]	[61]	2	hSpCas9	negative selection	10458020
55304685	55304708	19	-	28162770	SKM1	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-0.680645848776464	[67]	[74]	-5	hSpCas9	negative selection	10458021
55304843	55304866	19	-	28162770	SKM1	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	0.2166787701420544	[91]	[188]	2	hSpCas9	negative selection	10458022
55306297	55306320	19	+	28162770	SKM1	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	1.247039946407646	[50]	[213]	9	hSpCas9	negative selection	10458023
55306322	55306345	19	-	28162770	SKM1	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.36782286085801175	[63]	[145]	3	hSpCas9	negative selection	10458024
55287230	55287253	19	-	28162770	SKM1	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	-0.440131062678361	[65]	[85]	-4	hSpCas9	negative selection	10627381
55306335	55306358	19	+	28162770	SKM1	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	0.04589476597064929	[39]	[72]	0	hSpCas9	negative selection	10627382
55289534	55289557	19	+	28162770	SKM1	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-0.4683647434073049	[53]	[68]	-4	hSpCas9	negative selection	10627383
55289573	55289596	19	-	28162770	SKM1	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.01994107563391445	[38]	[67]	0	hSpCas9	negative selection	10627384
55304070	55304093	19	-	28162770	SKM1	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.0163797431888566	[118]	[207]	0	hSpCas9	negative selection	10627385
55304584	55304607	19	+	28162770	SKM1	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	0.27421361723729754	[28]	[61]	2	hSpCas9	negative selection	10627386
55304685	55304708	19	-	28162770	SKM1	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-0.680645848776464	[67]	[74]	-5	hSpCas9	negative selection	10627387
55304843	55304866	19	-	28162770	SKM1	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	0.2166787701420544	[91]	[188]	2	hSpCas9	negative selection	10627388
55306297	55306320	19	+	28162770	SKM1	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	1.247039946407646	[50]	[213]	9	hSpCas9	negative selection	10627389
55306322	55306345	19	-	28162770	SKM1	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.36782286085801175	[63]	[145]	3	hSpCas9	negative selection	10627390
55287230	55287253	19	-	28162770	PL21	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.5356258146714041	[232]	[146]	5	hSpCas9	negative selection	10796747
55306335	55306358	19	+	28162770	PL21	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	0.5327149535761908	[134]	[84]	4	hSpCas9	negative selection	10796748
55289534	55289557	19	+	28162770	PL21	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	0.26154015915346346	[183]	[95]	2	hSpCas9	negative selection	10796749
55289573	55289596	19	-	28162770	PL21	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.3287888513175079	[100]	[34]	-2	hSpCas9	negative selection	10796750
55304070	55304093	19	-	28162770	PL21	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	0.017275557339509806	[419]	[184]	0	hSpCas9	negative selection	10796751
55304584	55304607	19	+	28162770	PL21	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	-0.022252806847127937	[69]	[29]	0	hSpCas9	negative selection	10796752
55304685	55304708	19	-	28162770	PL21	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-0.25522997882474197	[265]	[96]	-2	hSpCas9	negative selection	10796753
55304843	55304866	19	-	28162770	PL21	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	0.006893538812388633	[342]	[149]	0	hSpCas9	negative selection	10796754
55306297	55306320	19	+	28162770	PL21	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	0.07867610200365296	[160]	[73]	0	hSpCas9	negative selection	10796755
55306322	55306345	19	-	28162770	PL21	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	-0.15805202438481386	[140]	[54]	-1	hSpCas9	negative selection	10796756
55287230	55287253	19	-	28162770	P31FUJ	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.8355349253487752	[133]	[280]	8	hSpCas9	negative selection	10966113
55306335	55306358	19	+	28162770	P31FUJ	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	0.2878010505103994	[190]	[273]	3	hSpCas9	negative selection	10966114
55289534	55289557	19	+	28162770	P31FUJ	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-0.43633559849951065	[189]	[164]	-4	hSpCas9	negative selection	10966115
55289573	55289596	19	-	28162770	P31FUJ	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	0.16260648811553258	[110]	[145]	1	hSpCas9	negative selection	10966116
55304070	55304093	19	-	28162770	P31FUJ	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.1921602199170327	[279]	[287]	-2	hSpCas9	negative selection	10966117
55304584	55304607	19	+	28162770	P31FUJ	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	0.09734639727795225	[69]	[87]	1	hSpCas9	negative selection	10966118
55304685	55304708	19	-	28162770	P31FUJ	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-1.4333351917870873	[392]	[170]	-7	hSpCas9	negative selection	10966119
55304843	55304866	19	-	28162770	P31FUJ	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	0.08768965835746467	[401]	[501]	0	hSpCas9	negative selection	10966120
55306297	55306320	19	+	28162770	P31FUJ	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	-0.10469737866669332	[279]	[305]	-1	hSpCas9	negative selection	10966121
55306322	55306345	19	-	28162770	P31FUJ	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.6428069333484311	[229]	[421]	7	hSpCas9	negative selection	10966122
55287230	55287253	19	-	28162770	OCIAML5	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	1.412040869635023	[55]	[268]	9	hSpCas9	negative selection	11135479
55306335	55306358	19	+	28162770	OCIAML5	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	-0.6681037360214022	[124]	[141]	-4	hSpCas9	negative selection	11135480
55289534	55289557	19	+	28162770	OCIAML5	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-0.4940190501699826	[70]	[90]	-3	hSpCas9	negative selection	11135481
55289573	55289596	19	-	28162770	OCIAML5	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	0.006577579890461593	[74]	[135]	0	hSpCas9	negative selection	11135482
55304070	55304093	19	-	28162770	OCIAML5	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.20504310201058934	[181]	[284]	-1	hSpCas9	negative selection	11135483
55304584	55304607	19	+	28162770	OCIAML5	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	1.062203555110119	[38]	[146]	8	hSpCas9	negative selection	11135484
55304685	55304708	19	-	28162770	OCIAML5	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-1.176417328018215	[148]	[118]	-6	hSpCas9	negative selection	11135485
55304843	55304866	19	-	28162770	OCIAML5	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	-0.2870884445969957	[314]	[465]	-2	hSpCas9	negative selection	11135486
55306297	55306320	19	+	28162770	OCIAML5	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	0.20726756851840536	[130]	[272]	1	hSpCas9	negative selection	11135487
55306322	55306345	19	-	28162770	OCIAML5	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	-0.14225258295775786	[117]	[192]	-1	hSpCas9	negative selection	11135488
55287230	55287253	19	-	28162770	EOL1	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.2849500142725326	[295]	[189]	2	hSpCas9	negative selection	11304845
55306335	55306358	19	+	28162770	EOL1	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	-0.3223669688999824	[177]	[74]	-2	hSpCas9	negative selection	11304846
55289534	55289557	19	+	28162770	EOL1	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-0.3640217263703968	[341]	[139]	-3	hSpCas9	negative selection	11304847
55289573	55289596	19	-	28162770	EOL1	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-1.870632436540967	[235]	[33]	-8	hSpCas9	negative selection	11304848
55304070	55304093	19	-	28162770	EOL1	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.012611354859234147	[583]	[304]	0	hSpCas9	negative selection	11304849
55304584	55304607	19	+	28162770	EOL1	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	-2.3642134593816286	[214]	[21]	-8	hSpCas9	negative selection	11304850
55304685	55304708	19	-	28162770	EOL1	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-1.5718780545489641	[394]	[69]	-7	hSpCas9	negative selection	11304851
55304843	55304866	19	-	28162770	EOL1	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	0.13033822556985275	[436]	[251]	1	hSpCas9	negative selection	11304852
55306297	55306320	19	+	28162770	EOL1	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	0.9626829004573054	[223]	[229]	8	hSpCas9	negative selection	11304853
55306322	55306345	19	-	28162770	EOL1	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	1.0132053913909316	[283]	[301]	8	hSpCas9	negative selection	11304854
55287230	55287253	19	-	28162770	MOLM13	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.6878114340567183	[333]	[388]	5	hSpCas9	negative selection	11474211
55306335	55306358	19	+	28162770	MOLM13	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	0.11996607812427196	[195]	[153]	0	hSpCas9	negative selection	11474212
55289534	55289557	19	+	28162770	MOLM13	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-1.413466121956802	[209]	[56]	-6	hSpCas9	negative selection	11474213
55289573	55289596	19	-	28162770	MOLM13	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-1.0145033855360293	[189]	[67]	-5	hSpCas9	negative selection	11474214
55304070	55304093	19	-	28162770	MOLM13	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.15404836291779578	[493]	[320]	-1	hSpCas9	negative selection	11474215
55304584	55304607	19	+	28162770	MOLM13	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	0.9572742222835039	[103]	[145]	7	hSpCas9	negative selection	11474216
55304685	55304708	19	-	28162770	MOLM13	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-1.2676748574450154	[342]	[102]	-6	hSpCas9	negative selection	11474217
55304843	55304866	19	-	28162770	MOLM13	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	-0.40385612778298013	[440]	[240]	-2	hSpCas9	negative selection	11474218
55306297	55306320	19	+	28162770	MOLM13	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	0.12908746809282035	[257]	[203]	0	hSpCas9	negative selection	11474219
55306322	55306345	19	-	28162770	MOLM13	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	-0.041286048398272046	[342]	[240]	0	hSpCas9	negative selection	11474220
55287230	55287253	19	-	28162770	HEL	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.6526203435143209	[290]	[292]	5	hSpCas9	negative selection	11643577
55306335	55306358	19	+	28162770	HEL	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	-0.4352636800009162	[208]	[98]	-3	hSpCas9	negative selection	11643578
55289534	55289557	19	+	28162770	HEL	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-1.2337781145646427	[234]	[63]	-6	hSpCas9	negative selection	11643579
55289573	55289596	19	-	28162770	HEL	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.40335758258909715	[158]	[76]	-3	hSpCas9	negative selection	11643580
55304070	55304093	19	-	28162770	HEL	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.38889277704875397	[414]	[202]	-3	hSpCas9	negative selection	11643581
55304584	55304607	19	+	28162770	HEL	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	-0.47108106755680523	[144]	[66]	-3	hSpCas9	negative selection	11643582
55304685	55304708	19	-	28162770	HEL	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-2.54772310044465	[282]	[30]	-8	hSpCas9	negative selection	11643583
55304843	55304866	19	-	28162770	HEL	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	0.2736627887562386	[380]	[294]	2	hSpCas9	negative selection	11643584
55306297	55306320	19	+	28162770	HEL	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	0.3765647186359958	[183]	[152]	3	hSpCas9	negative selection	11643585
55306322	55306345	19	-	28162770	HEL	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	-0.25941384460149836	[227]	[121]	-2	hSpCas9	negative selection	11643586
55287230	55287253	19	-	28162770	MV411	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	-0.4895280433834308	[169]	[101]	-4	hSpCas9	negative selection	11812943
55306335	55306358	19	+	28162770	MV411	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	0.3044684958191543	[123]	[128]	2	hSpCas9	negative selection	11812944
55289534	55289557	19	+	28162770	MV411	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-1.0603463617843172	[202]	[81]	-6	hSpCas9	negative selection	11812945
55289573	55289596	19	-	28162770	MV411	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.35173880915808176	[152]	[100]	-3	hSpCas9	negative selection	11812946
55304070	55304093	19	-	28162770	MV411	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-1.8708464672129343	[342]	[78]	-8	hSpCas9	negative selection	11812947
55304584	55304607	19	+	28162770	MV411	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	0.1743740885930518	[80]	[76]	1	hSpCas9	negative selection	11812948
55304685	55304708	19	-	28162770	MV411	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-1.5157046659425042	[240]	[70]	-7	hSpCas9	negative selection	11812949
55304843	55304866	19	-	28162770	MV411	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	-0.1849471920599653	[250]	[185]	-1	hSpCas9	negative selection	11812950
55306297	55306320	19	+	28162770	MV411	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	-0.8541004756792869	[205]	[95]	-5	hSpCas9	negative selection	11812951
55306322	55306345	19	-	28162770	MV411	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.5782620461585338	[193]	[243]	5	hSpCas9	negative selection	11812952
55287230	55287253	19	-	28162770	MONOMAC1	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	-0.07058851181861439	[130]	[142]	0	hSpCas9	negative selection	11982309
55306335	55306358	19	+	28162770	MONOMAC1	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	-0.3326919464171202	[77]	[70]	-3	hSpCas9	negative selection	11982310
55289534	55289557	19	+	28162770	MONOMAC1	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	0.1932782228080589	[102]	[134]	2	hSpCas9	negative selection	11982311
55289573	55289596	19	-	28162770	MONOMAC1	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	0.20406146126141644	[77]	[102]	2	hSpCas9	negative selection	11982312
55304070	55304093	19	-	28162770	MONOMAC1	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.9957060412509354	[206]	[118]	-7	hSpCas9	negative selection	11982313
55304584	55304607	19	+	28162770	MONOMAC1	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	0.1655332323251546	[55]	[71]	1	hSpCas9	negative selection	11982314
55304685	55304708	19	-	28162770	MONOMAC1	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-1.01695523058107	[172]	[97]	-7	hSpCas9	negative selection	11982315
55304843	55304866	19	-	28162770	MONOMAC1	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	0.6237385907603722	[213]	[377]	6	hSpCas9	negative selection	11982316
55306297	55306320	19	+	28162770	MONOMAC1	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	-0.3914148922264052	[118]	[103]	-3	hSpCas9	negative selection	11982317
55306322	55306345	19	-	28162770	MONOMAC1	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.4687799061464418	[132]	[210]	4	hSpCas9	negative selection	11982318
55287230	55287253	19	-	28162770	OCIAML2	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	0.46078308950042624	[34]	[266]	4	hSpCas9	negative selection	12151675
55306335	55306358	19	+	28162770	OCIAML2	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	-0.23541336354812958	[23]	[112]	-2	hSpCas9	negative selection	12151676
55289534	55289557	19	+	28162770	OCIAML2	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	-0.7925579201295235	[39]	[127]	-5	hSpCas9	negative selection	12151677
55289573	55289596	19	-	28162770	OCIAML2	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	-0.7081291389688177	[27]	[94]	-5	hSpCas9	negative selection	12151678
55304070	55304093	19	-	28162770	OCIAML2	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	-0.22874122827991605	[62]	[297]	-2	hSpCas9	negative selection	12151679
55304584	55304607	19	+	28162770	OCIAML2	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	-0.30769125411595566	[22]	[102]	-3	hSpCas9	negative selection	12151680
55304685	55304708	19	-	28162770	OCIAML2	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-1.0443650705400633	[31]	[85]	-6	hSpCas9	negative selection	12151681
55304843	55304866	19	-	28162770	OCIAML2	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	-0.16452669751648152	[54]	[271]	-1	hSpCas9	negative selection	12151682
55306297	55306320	19	+	28162770	OCIAML2	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	-0.3186267317971112	[35]	[159]	-3	hSpCas9	negative selection	12151683
55306322	55306345	19	-	28162770	OCIAML2	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	0.21903005414568816	[30]	[199]	2	hSpCas9	negative selection	12151684
55287230	55287253	19	-	28162770	OCIAML3	viability	GTGTTCGATGAGCTTCAGGATGG	BRSK1	ENSG00000160469	-0.2135838961266564	[57]	[150]	-2	hSpCas9	negative selection	12321041
55306335	55306358	19	+	28162770	OCIAML3	viability	AAAGCCCGTCCGCTTCCAGGTGG	BRSK1	ENSG00000160469	-0.48153291106575047	[36]	[79]	-4	hSpCas9	negative selection	12321042
55289534	55289557	19	+	28162770	OCIAML3	viability	GAAGGGGAGACTGACGCCCAAGG	BRSK1	ENSG00000160469	1.3084370502531635	[64]	[485]	9	hSpCas9	negative selection	12321043
55289573	55289596	19	-	28162770	OCIAML3	viability	CCAGCGCAGACACAATCTGGCGG	BRSK1	ENSG00000160469	1.575917361118149	[22]	[206]	9	hSpCas9	negative selection	12321044
55304070	55304093	19	-	28162770	OCIAML3	viability	GCTGGAGGACAGACCCGTGGAGG	BRSK1	ENSG00000160469	0.16498426017204193	[90]	[307]	1	hSpCas9	negative selection	12321045
55304584	55304607	19	+	28162770	OCIAML3	viability	GCTGGAGATGAGGCTCGAGGCGG	BRSK1	ENSG00000160469	-0.5693455860898939	[28]	[58]	-4	hSpCas9	negative selection	12321046
55304685	55304708	19	-	28162770	OCIAML3	viability	GGGGTGTGGAGCGGGCACTGGGG	BRSK1	ENSG00000160469	-0.6335360045108005	[73]	[143]	-5	hSpCas9	negative selection	12321047
55304843	55304866	19	-	28162770	OCIAML3	viability	GTTGAGACGACTCCTCCAGGCGG	BRSK1	ENSG00000160469	-0.09969050404300739	[103]	[292]	-1	hSpCas9	negative selection	12321048
55306297	55306320	19	+	28162770	OCIAML3	viability	GCCGAGTACAAGGCCAGTGGCGG	BRSK1	ENSG00000160469	-0.0858607366538379	[44]	[127]	0	hSpCas9	negative selection	12321049
55306322	55306345	19	-	28162770	OCIAML3	viability	GACGGGCTTTTGGAAGACGGAGG	BRSK1	ENSG00000160469	-0.6398113299372878	[47]	[92]	-5	hSpCas9	negative selection	12321050