Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:773
• Symbol:CACNA1A
• Description:calcium voltage-gated channel subunit alpha1 A

DataSource: http://genomecrispr.dkfz.de/#!/results/CACNA1A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
13298713	13298736	19	-	26472758	Jiyoye	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-1.4341268724750682	[128]	[35]	-7	hSpCas9	negative selection	22377
13298914	13298937	19	-	26472758	Jiyoye	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	2.3140659771143923	[11]	[44]	9	hSpCas9	negative selection	22378
13298558	13298581	19	-	26472758	Jiyoye	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	22379
13285131	13285154	19	-	26472758	Jiyoye	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	0.04617772193991879	[130]	[101]	0	hSpCas9	negative selection	22380
13262763	13262786	19	+	26472758	Jiyoye	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	1.2109099878847804	[113]	[198]	7	hSpCas9	negative selection	22381
13231833	13231856	19	+	26472758	Jiyoye	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.7978162264772501	[163]	[214]	5	hSpCas9	negative selection	22382
13506012	13506035	19	+	26472758	Jiyoye	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	3.214530303563477	[0]	[6]	9	hSpCas9	negative selection	22383
13452886	13452909	19	-	26472758	Jiyoye	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	0.14414097567207979	[161]	[134]	1	hSpCas9	negative selection	22384
13334454	13334477	19	-	26472758	Jiyoye	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	0.13341456907902122	[80]	[66]	1	hSpCas9	negative selection	22385
13317208	13317231	19	+	26472758	Jiyoye	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-3.293264336635219	[12]	[0]	-9	hSpCas9	negative selection	22386
13298713	13298736	19	-	26472758	KBM7	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-0.14041009653855063	[439,223]	[163,113]	-1	hSpCas9	negative selection	213495
13298914	13298937	19	-	26472758	KBM7	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-1.0443940069351774	[178,119]	[22,42]	-7	hSpCas9	negative selection	213496
13298558	13298581	19	-	26472758	KBM7	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-2.287425766094102	[166,152]	[16,13]	-8	hSpCas9	negative selection	213497
13285131	13285154	19	-	26472758	KBM7	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	0.009476733429313877	[438,289]	[183,156]	0	hSpCas9	negative selection	213498
13262763	13262786	19	+	26472758	KBM7	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.25776994291867344	[654,345]	[304,245]	2	hSpCas9	negative selection	213499
13231833	13231856	19	+	26472758	KBM7	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.36587688247222727	[775,488]	[409,345]	4	hSpCas9	negative selection	213500
13506012	13506035	19	+	26472758	KBM7	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.332015568382265	[65,36]	[22,14]	-3	hSpCas9	negative selection	213501
13452886	13452909	19	-	26472758	KBM7	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	0.18254468003527125	[1160,878]	[515,559]	1	hSpCas9	negative selection	213502
13334454	13334477	19	-	26472758	KBM7	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	-0.08971191609105689	[381,204]	[110,139]	-1	hSpCas9	negative selection	213503
13317208	13317231	19	+	26472758	KBM7	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-1.7696696110237409	[35,45]	[0,9]	-8	hSpCas9	negative selection	213504
13298713	13298736	19	-	26472758	Raji	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-1.2618502742921196	[154]	[14]	-7	hSpCas9	negative selection	404613
13298914	13298937	19	-	26472758	Raji	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-0.35204808326369763	[76]	[13]	-3	hSpCas9	negative selection	404614
13298558	13298581	19	-	26472758	Raji	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-3.1405439780699864	[75]	[1]	-9	hSpCas9	negative selection	404615
13285131	13285154	19	-	26472758	Raji	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-0.9105383726236629	[161]	[19]	-6	hSpCas9	negative selection	404616
13262763	13262786	19	+	26472758	Raji	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	-0.11103998375990283	[241]	[51]	-1	hSpCas9	negative selection	404617
13231833	13231856	19	+	26472758	Raji	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.37997676963223814	[350]	[105]	3	hSpCas9	negative selection	404618
13506012	13506035	19	+	26472758	Raji	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	0.47935231276055745	[33]	[10]	4	hSpCas9	negative selection	404619
13452886	13452909	19	-	26472758	Raji	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	0.010707515961925762	[431]	[100]	0	hSpCas9	negative selection	404620
13334454	13334477	19	-	26472758	Raji	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	-0.589689331669094	[213]	[32]	-5	hSpCas9	negative selection	404621
13317208	13317231	19	+	26472758	Raji	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	4.914738457431204	[0]	[6]	9	hSpCas9	negative selection	404622
13298713	13298736	19	-	26472758	K562	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-3.9926204696344025	[395]	[20]	-9	hSpCas9	negative selection	595731
13298914	13298937	19	-	26472758	K562	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-1.5705493785010325	[94]	[26]	-7	hSpCas9	negative selection	595732
13298558	13298581	19	-	26472758	K562	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-4.316296226808031	[117]	[4]	-9	hSpCas9	negative selection	595733
13285131	13285154	19	-	26472758	K562	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-2.256479508266235	[299]	[52]	-7	hSpCas9	negative selection	595734
13262763	13262786	19	+	26472758	K562	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.5672863830174237	[306]	[383]	4	hSpCas9	negative selection	595735
13231833	13231856	19	+	26472758	K562	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	-0.3871938663535308	[549]	[354]	-3	hSpCas9	negative selection	595736
13506012	13506035	19	+	26472758	K562	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-1.053261820974238	[58]	[23]	-5	hSpCas9	negative selection	595737
13452886	13452909	19	-	26472758	K562	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	-0.806482170633591	[749]	[361]	-5	hSpCas9	negative selection	595738
13334454	13334477	19	-	26472758	K562	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	-0.2794552636553033	[288]	[200]	-2	hSpCas9	negative selection	595739
13317208	13317231	19	+	26472758	K562	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-3.8430441135838915	[16]	[0]	-9	hSpCas9	negative selection	595740
13359751	13359774	19	+	26627737	DLD1	viability	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	0.7846350790591408	[35]	[19,17,19]	7	hSpCas9	negative selection	802771
13365406	13365429	19	+	26627737	DLD1	viability	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.19723695285476656	[680]	[206,232,127]	-2	hSpCas9	negative selection	802772
13371757	13371780	19	-	26627737	DLD1	viability	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.07153449116434485	[317]	[88,105,89]	0	hSpCas9	negative selection	802773
13452932	13452955	19	+	26627737	DLD1	viability	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	1.0978767693256237	[131]	[116,77,71]	8	hSpCas9	negative selection	802774
13455154	13455177	19	-	26627737	DLD1	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.8503833294698884	[407]	[16,48,39]	-8	hSpCas9	negative selection	802776
13505966	13505989	19	+	26627737	DLD1	viability	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.2425720085006624	[1221]	[595,294,456]	2	hSpCas9	negative selection	802780
13359751	13359774	19	+	26627737	GBM cells	viability after 5 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-1.3234785464507626	[6]	[0,1]	-9	hSpCas9	negative selection	885086
13365406	13365429	19	+	26627737	GBM cells	viability after 5 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.13521189824735158	[353]	[223,192]	2	hSpCas9	negative selection	885087
13371757	13371780	19	-	26627737	GBM cells	viability after 5 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.1214061094939104	[142]	[100,39]	-2	hSpCas9	negative selection	885088
13452932	13452955	19	+	26627737	GBM cells	viability after 5 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.347503933875556	[169]	[105,125]	5	hSpCas9	negative selection	885089
13455154	13455177	19	-	26627737	GBM cells	viability after 5 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.1894419995351615	[100]	[68,25]	-3	hSpCas9	negative selection	885091
13505966	13505989	19	+	26627737	GBM cells	viability after 5 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	-0.04918502320228457	[818]	[417,430]	0	hSpCas9	negative selection	885095
13359751	13359774	19	+	26627737	GBM cells	viability after 13 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-1.3906628202731195	[6]	[1,0]	-9	hSpCas9	negative selection	967401
13365406	13365429	19	+	26627737	GBM cells	viability after 13 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.021913576575960603	[353]	[197,181]	0	hSpCas9	negative selection	967402
13371757	13371780	19	-	26627737	GBM cells	viability after 13 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	0.20699545834341315	[142]	[104,76]	2	hSpCas9	negative selection	967403
13452932	13452955	19	+	26627737	GBM cells	viability after 13 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.6431527659293227	[169]	[180,113]	7	hSpCas9	negative selection	967404
13455154	13455177	19	-	26627737	GBM cells	viability after 13 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.046987492636117	[100]	[36,17]	-8	hSpCas9	negative selection	967406
13505966	13505989	19	+	26627737	GBM cells	viability after 13 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	-0.07942750056792236	[818]	[526,333]	-1	hSpCas9	negative selection	967410
13359751	13359774	19	+	26627737	GBM cells	viability after 21 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.6180748188513157	[6]	[2,1]	-5	hSpCas9	negative selection	1049716
13365406	13365429	19	+	26627737	GBM cells	viability after 21 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.455915379605627	[353]	[146,133]	-4	hSpCas9	negative selection	1049717
13371757	13371780	19	-	26627737	GBM cells	viability after 21 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.35100452066663057	[142]	[62,58]	-3	hSpCas9	negative selection	1049718
13452932	13452955	19	+	26627737	GBM cells	viability after 21 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.8968274990221118	[169]	[207,138]	8	hSpCas9	negative selection	1049719
13455154	13455177	19	-	26627737	GBM cells	viability after 21 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.13797431885701839	[100]	[52,46]	-1	hSpCas9	negative selection	1049721
13505966	13505989	19	+	26627737	GBM cells	viability after 21 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	-0.0744891198370714	[818]	[432,412]	0	hSpCas9	negative selection	1049725
13359751	13359774	19	+	26627737	RPE1	viability after 9 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	0.31639698891413337	[83]	[30,34]	2	hSpCas9	negative selection	1132031
13365406	13365429	19	+	26627737	RPE1	viability after 9 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.8142578222260738	[760]	[352,503]	5	hSpCas9	negative selection	1132032
13371757	13371780	19	-	26627737	RPE1	viability after 9 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	0.8266829137525324	[280]	[169,137]	5	hSpCas9	negative selection	1132033
13452932	13452955	19	+	26627737	RPE1	viability after 9 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.16089281304555691	[483]	[121,152]	-1	hSpCas9	negative selection	1132034
13455154	13455177	19	-	26627737	RPE1	viability after 9 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.43950162051014674	[235]	[73,133]	3	hSpCas9	negative selection	1132036
13505966	13505989	19	+	26627737	RPE1	viability after 9 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.43159230696549766	[2217]	[829,1073]	3	hSpCas9	negative selection	1132040
13359751	13359774	19	+	26627737	RPE1	viability after 12 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.2811931201347724	[83]	[20,15]	-2	hSpCas9	negative selection	1214346
13365406	13365429	19	+	26627737	RPE1	viability after 12 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	1.0603257233412062	[760]	[370,484]	6	hSpCas9	negative selection	1214347
13371757	13371780	19	-	26627737	RPE1	viability after 12 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.08682715536215202	[280]	[107,31]	0	hSpCas9	negative selection	1214348
13452932	13452955	19	+	26627737	RPE1	viability after 12 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.4915931923372501	[483]	[74,110]	-3	hSpCas9	negative selection	1214349
13455154	13455177	19	-	26627737	RPE1	viability after 12 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.48828077016087823	[235]	[51,37]	-3	hSpCas9	negative selection	1214351
13505966	13505989	19	+	26627737	RPE1	viability after 12 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.4994293876497822	[2217]	[855,827]	3	hSpCas9	negative selection	1214355
13359751	13359774	19	+	26627737	RPE1	viability after 15 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.3991936025777951	[83]	[16,18]	-3	hSpCas9	negative selection	1296661
13365406	13365429	19	+	26627737	RPE1	viability after 15 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.6565908446191171	[760]	[291,384]	4	hSpCas9	negative selection	1296662
13371757	13371780	19	-	26627737	RPE1	viability after 15 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	1.2749176637961257	[280]	[256,129]	7	hSpCas9	negative selection	1296663
13452932	13452955	19	+	26627737	RPE1	viability after 15 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.2828519948084627	[483]	[218,115]	1	hSpCas9	negative selection	1296664
13455154	13455177	19	-	26627737	RPE1	viability after 15 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.16901211026353957	[235]	[99,50]	1	hSpCas9	negative selection	1296666
13505966	13505989	19	+	26627737	RPE1	viability after 15 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.7792986278708609	[2217]	[1394,769]	5	hSpCas9	negative selection	1296670
13359751	13359774	19	+	26627737	RPE1	viability after 18 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.19032534984775262	[83]	[15,23]	-1	hSpCas9	negative selection	1378976
13365406	13365429	19	+	26627737	RPE1	viability after 18 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.9374315464037731	[760]	[241,554]	5	hSpCas9	negative selection	1378977
13371757	13371780	19	-	26627737	RPE1	viability after 18 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	0.21451815430078547	[280]	[43,134]	1	hSpCas9	negative selection	1378978
13452932	13452955	19	+	26627737	RPE1	viability after 18 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.2015926475455161	[483]	[115,110]	-1	hSpCas9	negative selection	1378979
13455154	13455177	19	-	26627737	RPE1	viability after 18 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.21555430505627804	[235]	[57,90]	1	hSpCas9	negative selection	1378981
13505966	13505989	19	+	26627737	RPE1	viability after 18 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.7225696315177257	[2217]	[1022,949]	4	hSpCas9	negative selection	1378985
13359751	13359774	19	+	26627737	HeLa	viability after 8 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-1.281029003453521	[643]	[143,103,104]	-8	hSpCas9	negative selection	1461291
13365406	13365429	19	+	26627737	HeLa	viability after 8 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.2948552698641446	[519]	[169,330,305]	2	hSpCas9	negative selection	1461292
13371757	13371780	19	-	26627737	HeLa	viability after 8 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	1.3556371058476473	[87]	[89,100,100]	8	hSpCas9	negative selection	1461293
13452932	13452955	19	+	26627737	HeLa	viability after 8 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.08254282920464973	[236]	[24,84,192]	0	hSpCas9	negative selection	1461294
13455154	13455177	19	-	26627737	HeLa	viability after 8 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-2.108120625324803	[328]	[1,1,84]	-9	hSpCas9	negative selection	1461296
13505966	13505989	19	+	26627737	HeLa	viability after 8 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.1634411709361676	[997]	[598,533,359]	1	hSpCas9	negative selection	1461300
13359751	13359774	19	+	26627737	HeLa	viability after 12 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-1.0190968191023568	[643]	[157,109,128]	-7	hSpCas9	negative selection	1543606
13365406	13365429	19	+	26627737	HeLa	viability after 12 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.20689968169198852	[519]	[306,302,129]	1	hSpCas9	negative selection	1543607
13371757	13371780	19	-	26627737	HeLa	viability after 12 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	1.9595053339699409	[87]	[112,98,215]	9	hSpCas9	negative selection	1543608
13452932	13452955	19	+	26627737	HeLa	viability after 12 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.7591096594937332	[236]	[18,52,100]	-6	hSpCas9	negative selection	1543609
13455154	13455177	19	-	26627737	HeLa	viability after 12 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-2.788538187022544	[328]	[2,5,50]	-9	hSpCas9	negative selection	1543611
13505966	13505989	19	+	26627737	HeLa	viability after 12 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.6151469302508028	[997]	[873,586,445]	5	hSpCas9	negative selection	1543615
13359751	13359774	19	+	26627737	HeLa	viability after 15 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.9321720340631405	[643]	[102,191,115]	-7	hSpCas9	negative selection	1625921
13365406	13365429	19	+	26627737	HeLa	viability after 15 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.0883939129481478	[519]	[156,125,406]	0	hSpCas9	negative selection	1625922
13371757	13371780	19	-	26627737	HeLa	viability after 15 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	1.0488081954672424	[87]	[82,79,57]	7	hSpCas9	negative selection	1625923
13452932	13452955	19	+	26627737	HeLa	viability after 15 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.13343764849253126	[236]	[57,46,221]	1	hSpCas9	negative selection	1625924
13455154	13455177	19	-	26627737	HeLa	viability after 15 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.7730975038743	[328]	[56,0,60]	-9	hSpCas9	negative selection	1625926
13505966	13505989	19	+	26627737	HeLa	viability after 15 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.5344987215377319	[997]	[546,412,823]	4	hSpCas9	negative selection	1625930
13359751	13359774	19	+	26627737	HeLa	viability after 18 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.9698771926197962	[643]	[62,157,115]	-7	hSpCas9	negative selection	1708236
13365406	13365429	19	+	26627737	HeLa	viability after 18 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.05974850749946908	[519]	[96,103,406]	0	hSpCas9	negative selection	1708237
13371757	13371780	19	-	26627737	HeLa	viability after 18 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	1.0519674646029267	[87]	[56,64,57]	7	hSpCas9	negative selection	1708238
13452932	13452955	19	+	26627737	HeLa	viability after 18 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.16360595486142337	[236]	[39,42,221]	1	hSpCas9	negative selection	1708239
13455154	13455177	19	-	26627737	HeLa	viability after 18 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.7377175830445282	[328]	[39,0,60]	-9	hSpCas9	negative selection	1708241
13505966	13505989	19	+	26627737	HeLa	viability after 18 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.5400348480525017	[997]	[368,344,823]	4	hSpCas9	negative selection	1708245
13359751	13359774	19	+	26627737	HCT116	viability after 6 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-3.3474692326293773	[281]	[4,3]	-9	hSpCas9	negative selection	1790551
13365406	13365429	19	+	26627737	HCT116	viability after 6 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.9010640618457366	[1043]	[553,169]	5	hSpCas9	negative selection	1790552
13371757	13371780	19	-	26627737	HCT116	viability after 6 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-4.118814626438109	[495]	[8,1]	-9	hSpCas9	negative selection	1790553
13452932	13452955	19	+	26627737	HCT116	viability after 6 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.44822936820393244	[441]	[77,35]	-3	hSpCas9	negative selection	1790554
13455154	13455177	19	-	26627737	HCT116	viability after 6 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.5104066946206345	[149]	[22,12]	-3	hSpCas9	negative selection	1790556
13505966	13505989	19	+	26627737	HCT116	viability after 6 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	1.126017146591058	[1226]	[420,420]	6	hSpCas9	negative selection	1790560
13359751	13359774	19	+	26627737	HCT116	viability after 8 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	0.4653721095359383	[268]	[238,123,250]	5	hSpCas9	negative selection	1872866
13365406	13365429	19	+	26627737	HCT116	viability after 8 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.26811059934228926	[441]	[148,188,266]	-3	hSpCas9	negative selection	1872867
13371757	13371780	19	-	26627737	HCT116	viability after 8 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.5299746905949232	[205]	[86,70,77]	-6	hSpCas9	negative selection	1872868
13452932	13452955	19	+	26627737	HCT116	viability after 8 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.11013628481903193	[126]	[92,65,67]	1	hSpCas9	negative selection	1872869
13455154	13455177	19	-	26627737	HCT116	viability after 8 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.2147322760324215	[99]	[70,59,60]	2	hSpCas9	negative selection	1872871
13505966	13505989	19	+	26627737	HCT116	viability after 8 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.22594182429103649	[855]	[548,562,542]	2	hSpCas9	negative selection	1872875
13359751	13359774	19	+	26627737	HCT116	viability after 9 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-1.6032369830792208	[281]	[2,41]	-8	hSpCas9	negative selection	1955181
13365406	13365429	19	+	26627737	HCT116	viability after 9 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.6582958246950215	[1043]	[530,367]	5	hSpCas9	negative selection	1955182
13371757	13371780	19	-	26627737	HCT116	viability after 9 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.3445239241546338	[495]	[129,83]	-2	hSpCas9	negative selection	1955183
13452932	13452955	19	+	26627737	HCT116	viability after 9 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.4935381794415551	[441]	[156,25]	-3	hSpCas9	negative selection	1955184
13455154	13455177	19	-	26627737	HCT116	viability after 9 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-4.0360957041386465	[149]	[2,1]	-9	hSpCas9	negative selection	1955186
13505966	13505989	19	+	26627737	HCT116	viability after 9 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.8006203137704598	[1226]	[649,507]	5	hSpCas9	negative selection	1955190
13359751	13359774	19	+	26627737	HCT116	viability after 12 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.05574098650348275	[268]	[142,118,144]	0	hSpCas9	negative selection	2037496
13365406	13365429	19	+	26627737	HCT116	viability after 12 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.6339052281279041	[441]	[119,162,168]	-6	hSpCas9	negative selection	2037497
13371757	13371780	19	-	26627737	HCT116	viability after 12 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.04708755829492062	[205]	[55,119,142]	0	hSpCas9	negative selection	2037498
13452932	13452955	19	+	26627737	HCT116	viability after 12 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.4526847615716192	[126]	[118,107,44]	4	hSpCas9	negative selection	2037499
13455154	13455177	19	-	26627737	HCT116	viability after 12 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.8254983660221733	[99]	[60,42,176]	7	hSpCas9	negative selection	2037501
13505966	13505989	19	+	26627737	HCT116	viability after 12 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.42330630538919745	[855]	[672,618,511]	4	hSpCas9	negative selection	2037505
13359751	13359774	19	+	26627737	HCT116	viability after 15 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	0.6410849219884731	[268]	[242,154,323]	6	hSpCas9	negative selection	2119811
13365406	13365429	19	+	26627737	HCT116	viability after 15 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.058159184433018596	[441]	[181,305,235]	0	hSpCas9	negative selection	2119812
13371757	13371780	19	-	26627737	HCT116	viability after 15 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.00028370522613530014	[205]	[56,139,149]	0	hSpCas9	negative selection	2119813
13452932	13452955	19	+	26627737	HCT116	viability after 15 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.3375410401968255	[126]	[149,80,52]	3	hSpCas9	negative selection	2119814
13455154	13455177	19	-	26627737	HCT116	viability after 15 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.6398565671274763	[99]	[40,85,134]	6	hSpCas9	negative selection	2119816
13505966	13505989	19	+	26627737	HCT116	viability after 15 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.549318410273961	[855]	[888,583,705]	5	hSpCas9	negative selection	2119820
13359751	13359774	19	+	26627737	HCT116	viability after 18 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	0.2724797905697283	[268]	[153,91,232]	2	hSpCas9	negative selection	2202126
13365406	13365429	19	+	26627737	HCT116	viability after 18 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.13907490386305044	[441]	[334,150,224]	1	hSpCas9	negative selection	2202127
13371757	13371780	19	-	26627737	HCT116	viability after 18 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.7744822071126429	[205]	[32,39,104]	-6	hSpCas9	negative selection	2202128
13452932	13452955	19	+	26627737	HCT116	viability after 18 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.9679493837269599	[126]	[177,115,63]	7	hSpCas9	negative selection	2202129
13455154	13455177	19	-	26627737	HCT116	viability after 18 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.13119171257026574	[99]	[42,29,88]	1	hSpCas9	negative selection	2202131
13505966	13505989	19	+	26627737	HCT116	viability after 18 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.28636822110347016	[855]	[694,298,534]	2	hSpCas9	negative selection	2202135
13506002	13506025	19	+	24336569	HL60	viability	TAACCGTGAGGCAGTTCTGTCGG	CACNA1A	ENSG00000141837	-0.403187977943423	[882]	[1412]	-4	hSpCas9	negative selection	2254103
13506007	13506030	19	+	24336569	HL60	viability	GTGAGGCAGTTCTGTCGGACGGG	CACNA1A	ENSG00000141837	-0.3180163780017753	[528]	[897]	-3	hSpCas9	negative selection	2254104
13506047	13506070	19	-	24336569	HL60	viability	GGCGCAGAGAGCGCGGACCATGG	CACNA1A	ENSG00000141837	0.20191461922623277	[621]	[1513]	2	hSpCas9	negative selection	2254105
13506054	13506077	19	-	24336569	HL60	viability	AGTCAATGGCGCAGAGAGCGCGG	CACNA1A	ENSG00000141837	-0.2210701679244781	[823]	[1495]	-2	hSpCas9	negative selection	2254106
13506068	13506091	19	-	24336569	HL60	viability	AAGGATGTACAAGCAGTCAATGG	CACNA1A	ENSG00000141837	0.8847110217228374	[560]	[2191]	7	hSpCas9	negative selection	2254107
13506124	13506147	19	-	24336569	HL60	viability	AGCGGAGGCGGGCGAGGAGCCGG	CACNA1A	ENSG00000141837	-0.5063861888395843	[536]	[799]	-4	hSpCas9	negative selection	2254108
13506135	13506158	19	-	24336569	HL60	viability	TGGTCGTGGGCAGCGGAGGCGGG	CACNA1A	ENSG00000141837	0.3541956221042635	[1284]	[3475]	3	hSpCas9	negative selection	2254109
13506186	13506209	19	-	24336569	HL60	viability	ACGAGATGCCGGCCCGCTACGGG	CACNA1A	ENSG00000141837	0.34737919817497803	[519]	[1399]	3	hSpCas9	negative selection	2254110
13506197	13506220	19	+	24336569	HL60	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.5390920014219993	[386]	[1189]	5	hSpCas9	negative selection	2254111
13506211	13506234	19	-	24336569	HL60	viability	CTTTGCAGAATGGCCCGCTTCGG	CACNA1A	ENSG00000141837	-0.23264256127590785	[582]	[1049]	-2	hSpCas9	negative selection	2254112
13506002	13506025	19	+	24336569	KBM7	viability	TAACCGTGAGGCAGTTCTGTCGG	CACNA1A	ENSG00000141837	0.5826455179544352	[554]	[2266]	5	hSpCas9	negative selection	2321280
13506007	13506030	19	+	24336569	KBM7	viability	GTGAGGCAGTTCTGTCGGACGGG	CACNA1A	ENSG00000141837	0.5565135580850006	[351]	[1411]	5	hSpCas9	negative selection	2321281
13506047	13506070	19	-	24336569	KBM7	viability	GGCGCAGAGAGCGCGGACCATGG	CACNA1A	ENSG00000141837	-0.250299236198803	[504]	[1157]	-2	hSpCas9	negative selection	2321282
13506054	13506077	19	-	24336569	KBM7	viability	AGTCAATGGCGCAGAGAGCGCGG	CACNA1A	ENSG00000141837	-0.5704176454266096	[875]	[1608]	-4	hSpCas9	negative selection	2321283
13506068	13506091	19	-	24336569	KBM7	viability	AAGGATGTACAAGCAGTCAATGG	CACNA1A	ENSG00000141837	-0.2602684203094877	[778]	[1773]	-2	hSpCas9	negative selection	2321284
13506124	13506147	19	-	24336569	KBM7	viability	AGCGGAGGCGGGCGAGGAGCCGG	CACNA1A	ENSG00000141837	-1.924961810070224	[464]	[333]	-8	hSpCas9	negative selection	2321285
13506135	13506158	19	-	24336569	KBM7	viability	TGGTCGTGGGCAGCGGAGGCGGG	CACNA1A	ENSG00000141837	0.2131867717359246	[932]	[2949]	2	hSpCas9	negative selection	2321286
13506186	13506209	19	-	24336569	KBM7	viability	ACGAGATGCCGGCCCGCTACGGG	CACNA1A	ENSG00000141837	-0.6831566396596345	[457]	[777]	-5	hSpCas9	negative selection	2321287
13506197	13506220	19	+	24336569	KBM7	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.2510569915267729	[430]	[1398]	2	hSpCas9	negative selection	2321288
13506211	13506234	19	-	24336569	KBM7	viability	CTTTGCAGAATGGCCCGCTTCGG	CACNA1A	ENSG00000141837	-0.1643376715769406	[513]	[1250]	-1	hSpCas9	negative selection	2321289
13259258	13259281	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCTCAGCCTCCTGAGTAGCCGG	CACNA1A	ENSG00000141837	-0.29935217365489764	[71,81]	[9,16]	-1	dCas9-VP64	positive selection	2389898
13433416	13433439	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACACCACTGCACTCCAGCCTCGG	CACNA1A	ENSG00000141837	-0.9885038950311584	[179,367]	[28,30]	-6	dCas9-VP64	positive selection	2395969
13416224	13416247	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCTGTGGTCCCAGCTACTCGG	CACNA1A	ENSG00000141837	-1.0019767452838857	[448,49]	[42,8]	-6	dCas9-VP64	positive selection	2399846
13434489	13434512	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGTAATTGGATCATGGGGGCAG	CACNA1A	ENSG00000141837	0.13367549039552562	[0,268]	[0,66]	0	dCas9-VP64	positive selection	2403181
13495496	13495519	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGACCATCCTGGCTAACAGGG	CACNA1A	ENSG00000141837	-1.1174807317499718	[30,74]	[4,4]	-6	dCas9-VP64	positive selection	2405357
13548633	13548656	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CATGCCACTGCACTCCAGCCAAG	CACNA1A	ENSG00000141837	0.07732275682136047	[9,85]	[6,14]	0	dCas9-VP64	positive selection	2406699
13528937	13528960	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCACTTTGGTAGGCCAAGGTAGG	CACNA1A	ENSG00000141837	0.5553943551630764	[8,10]	[3,1]	2	dCas9-VP64	positive selection	2418561
13528940	13528963	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACCTTGGCCTACCAAAGTGCTGG	CACNA1A	ENSG00000141837	2.0515604839822705	[68,78]	[51,85]	7	dCas9-VP64	positive selection	2418602
13290667	13290690	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTTGGGCGG	CACNA1A	ENSG00000141837	-1.8840232515636643	[4,58]	[0,1]	-9	dCas9-VP64	positive selection	2423304
13600759	13600782	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGGCTGGAGTGCAGTGGTGG	CACNA1A	ENSG00000141837	-1.2921060931449064	[66,2]	[3,0]	-7	dCas9-VP64	positive selection	2435217
13583508	13583531	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCTCAGCACTTTGGGGGG	CACNA1A	ENSG00000141837	0.15607651136927458	[32,6]	[6,1]	0	dCas9-VP64	positive selection	2438165
13622164	13622187	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTCTGTCGCCCCAG	CACNA1A	ENSG00000141837	-0.5315818005101806	[14,129]	[5,15]	-3	dCas9-VP64	positive selection	2444199
13506550	13506573	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCGAGGCAAAAAATAACCGAGG	CACNA1A	ENSG00000141837	-0.5318284831019165	[73,33]	[12,1]	-3	dCas9-VP64	positive selection	2455236
13506521	13506544	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCCTCCCCCCTCCTCCCCGGG	CACNA1A	ENSG00000141837	2.912420072933693	[147,215]	[25,601]	8	dCas9-VP64	positive selection	2455237
13506580	13506603	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGTGGACTGGGGATTGCCTGG	CACNA1A	ENSG00000141837	0.5203348433599564	[8,29]	[1,9]	2	dCas9-VP64	positive selection	2455238
13378700	13378723	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCCAGGCTGGAGTGCAGCAG	CACNA1A	ENSG00000141837	-0.014347572194705283	[459,63]	[82,26]	0	dCas9-VP64	positive selection	2457875
13347958	13347981	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCCAGGCTGGAGTGCAGGGG	CACNA1A	ENSG00000141837	-0.014347572194705283	[459,63]	[82,26]	0	dCas9-VP64	positive selection	2457918
13309208	13309231	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAGACTAGCCTGGCCAACACAG	CACNA1A	ENSG00000141837	0.3601150748164519	[269,268]	[95,53]	1	dCas9-VP64	positive selection	2458908
13328108	13328131	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGTCTTGAACGG	CACNA1A	ENSG00000141837	-1.0535100245106288	[123,340]	[31,16]	-6	dCas9-VP64	positive selection	2459101
13386050	13386073	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGTGATCCGCCCACCTTAG	CACNA1A	ENSG00000141837	-1.8266088487663314	[149,166]	[13,3]	-8	dCas9-VP64	positive selection	2465111
13234223	13234246	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCGGG	CACNA1A	ENSG00000141837	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468721
13384654	13384677	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCACCACTGCACTCCAGCCTAG	CACNA1A	ENSG00000141837	3.0347564003538725	[8,6]	[27,0]	8	dCas9-VP64	positive selection	2470755
13293487	13293510	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCACCACTGCACTCCAGCCGGG	CACNA1A	ENSG00000141837	3.0347564003538725	[8,6]	[27,0]	8	dCas9-VP64	positive selection	2470789
13310864	13310887	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACTGCAACCTCTGCCTCCCCAG	CACNA1A	ENSG00000141837	-0.5062023598928189	[190,459]	[52,47]	-2	dCas9-VP64	positive selection	2470952
13454444	13454467	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACTGCAACCTCTGCCTCCCGGG	CACNA1A	ENSG00000141837	-0.5062023598928189	[190,459]	[52,47]	-2	dCas9-VP64	positive selection	2470995
13614611	13614634	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGTTTGAGACCAGCTCAG	CACNA1A	ENSG00000141837	0.362963240197711	[121,64]	[24,26]	1	dCas9-VP64	positive selection	2472569
13434863	13434886	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAGCCTTGACCTCCCAGG	CACNA1A	ENSG00000141837	-0.13547020725059378	[412,709]	[41,189]	0	dCas9-VP64	positive selection	2474494
13259258	13259281	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCTCAGCCTCCTGAGTAGCCGG	CACNA1A	ENSG00000141837	0.6576184974956476	[246,231]	[69,172]	5	dCas9-VP64	positive selection	2485153
13433416	13433439	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACACCACTGCACTCCAGCCTCGG	CACNA1A	ENSG00000141837	0.0430865282742412	[329,462]	[142,122]	0	dCas9-VP64	positive selection	2491224
13416224	13416247	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCTGTGGTCCCAGCTACTCGG	CACNA1A	ENSG00000141837	0.3516116254360768	[311,292]	[125,125]	3	dCas9-VP64	positive selection	2495101
13434489	13434512	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGTAATTGGATCATGGGGGCAG	CACNA1A	ENSG00000141837	0.3137604569902953	[35,90]	[26,23]	2	dCas9-VP64	positive selection	2498436
13495496	13495519	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGACCATCCTGGCTAACAGGG	CACNA1A	ENSG00000141837	-0.3866569806865121	[139,148]	[35,34]	-4	dCas9-VP64	positive selection	2500612
13548633	13548656	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CATGCCACTGCACTCCAGCCAAG	CACNA1A	ENSG00000141837	-0.2649826808475564	[463,106]	[139,20]	-3	dCas9-VP64	positive selection	2501954
13528937	13528960	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCACTTTGGTAGGCCAAGGTAGG	CACNA1A	ENSG00000141837	-0.8671691922358802	[189,124]	[32,22]	-7	dCas9-VP64	positive selection	2513816
13528940	13528963	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACCTTGGCCTACCAAAGTGCTGG	CACNA1A	ENSG00000141837	-0.05988777688383007	[304,168]	[116,33]	0	dCas9-VP64	positive selection	2513857
13290667	13290690	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTTGGGCGG	CACNA1A	ENSG00000141837	-0.3040415459965904	[20,19]	[5,3]	-3	dCas9-VP64	positive selection	2518559
13600759	13600782	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGGCTGGAGTGCAGTGGTGG	CACNA1A	ENSG00000141837	0.4307409852930557	[33,0]	[13,0]	3	dCas9-VP64	positive selection	2530472
13583508	13583531	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCTCAGCACTTTGGGGGG	CACNA1A	ENSG00000141837	-0.09854114350347812	[128,153]	[28,55]	-1	dCas9-VP64	positive selection	2533420
13622164	13622187	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTCTGTCGCCCCAG	CACNA1A	ENSG00000141837	0.35722745049512583	[51,32]	[17,15]	3	dCas9-VP64	positive selection	2539454
13506550	13506573	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCGAGGCAAAAAATAACCGAGG	CACNA1A	ENSG00000141837	-0.21424162741153024	[114,77]	[39,14]	-2	dCas9-VP64	positive selection	2550491
13506521	13506544	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCCTCCCCCCTCCTCCCCGGG	CACNA1A	ENSG00000141837	0.8190221441567589	[97,184]	[85,75]	5	dCas9-VP64	positive selection	2550492
13506580	13506603	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGTGGACTGGGGATTGCCTGG	CACNA1A	ENSG00000141837	1.9065595525969259	[54,144]	[155,89]	8	dCas9-VP64	positive selection	2550493
13378700	13378723	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCCAGGCTGGAGTGCAGCAG	CACNA1A	ENSG00000141837	-0.8839666549432982	[334,175]	[40,48]	-8	dCas9-VP64	positive selection	2553130
13347958	13347981	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCCAGGCTGGAGTGCAGGGG	CACNA1A	ENSG00000141837	-0.8839666549432982	[334,175]	[40,48]	-8	dCas9-VP64	positive selection	2553173
13309208	13309231	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAGACTAGCCTGGCCAACACAG	CACNA1A	ENSG00000141837	-0.8374586120276372	[108,300]	[27,44]	-7	dCas9-VP64	positive selection	2554163
13328108	13328131	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGTCTTGAACGG	CACNA1A	ENSG00000141837	-0.34576882282637056	[98,186]	[34,36]	-4	dCas9-VP64	positive selection	2554356
13386050	13386073	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGTGATCCGCCCACCTTAG	CACNA1A	ENSG00000141837	0.6108739619638027	[154,293]	[174,51]	4	dCas9-VP64	positive selection	2560366
13234223	13234246	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCGGG	CACNA1A	ENSG00000141837	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2563976
13384654	13384677	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCACCACTGCACTCCAGCCTAG	CACNA1A	ENSG00000141837	0.038175304513698105	[60,77]	[26,18]	0	dCas9-VP64	positive selection	2566010
13293487	13293510	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCACCACTGCACTCCAGCCGGG	CACNA1A	ENSG00000141837	0.038175304513698105	[60,77]	[26,18]	0	dCas9-VP64	positive selection	2566044
13310864	13310887	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACTGCAACCTCTGCCTCCCCAG	CACNA1A	ENSG00000141837	0.6085406430083108	[122,167]	[85,58]	4	dCas9-VP64	positive selection	2566207
13454444	13454467	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACTGCAACCTCTGCCTCCCGGG	CACNA1A	ENSG00000141837	0.6085406430083108	[122,167]	[85,58]	4	dCas9-VP64	positive selection	2566250
13614611	13614634	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGTTTGAGACCAGCTCAG	CACNA1A	ENSG00000141837	-1.016658803330618	[35,140]	[14,11]	-8	dCas9-VP64	positive selection	2567824
13434863	13434886	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAGCCTTGACCTCCCAGG	CACNA1A	ENSG00000141837	0.2584978845854493	[172,83]	[35,62]	2	dCas9-VP64	positive selection	2569749
13506184	13506207	19	-	27260157	DLD1	viability	GAGATGCCGGCCCGCTACGGGGG	CACNA1A	ENSG00000141837	0.0498943740690472	[]	[]	3	hSpCas9	negative selection	2576239
13452916	13452939	19	+	27260157	DLD1	viability	TCCTCAAGTAGGAGCCTTTGTGG	CACNA1A	ENSG00000141837	0.480777941324471	[]	[]	8	hSpCas9	negative selection	2578166
13506141	13506164	19	+	27260157	DLD1	viability	TCCGCTGCCCACGACCACCCCGG	CACNA1A	ENSG00000141837	-0.127154166168581	[]	[]	-1	hSpCas9	negative selection	2580546
13506007	13506030	19	+	27260157	DLD1	viability	GTGAGGCAGTTCTGTCGGACGGG	CACNA1A	ENSG00000141837	-0.367702810877184	[]	[]	-3	hSpCas9	negative selection	2582202
13506197	13506220	19	-	27260157	DLD1	viability	CCGCTTCGGAGACGAGATGCCGG	CACNA1A	ENSG00000141837	-0.399686018383113	[]	[]	-3	hSpCas9	negative selection	2583312
13506197	13506220	19	+	27260157	DLD1	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.520799862048008	[]	[]	8	hSpCas9	negative selection	2583577
13505990	13506013	19	+	27260157	DLD1	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.100863360129082	[]	[]	3	hSpCas9	negative selection	2585636
13506211	13506234	19	-	27260157	DLD1	viability	CTTTGCAGAATGGCCCGCTTCGG	CACNA1A	ENSG00000141837	0.439752858808596	[]	[]	7	hSpCas9	negative selection	2605363
13506135	13506158	19	-	27260157	DLD1	viability	TGGTCGTGGGCAGCGGAGGCGGG	CACNA1A	ENSG00000141837	0.0368134364923183	[]	[]	0	hSpCas9	negative selection	2608271
13505997	13506020	19	-	27260157	DLD1	viability	AGAACTGCCTCACGGTTAACCGG	CACNA1A	ENSG00000141837	-0.743663589900039	[]	[]	-5	hSpCas9	negative selection	2613129
13506078	13506101	19	+	27260157	DLD1	viability	CTTGTACATCCTTTGCGCCCCGG	CACNA1A	ENSG00000141837	-0.77184854887861	[]	[]	-6	hSpCas9	negative selection	2613733
13506068	13506091	19	-	27260157	DLD1	viability	AAGGATGTACAAGCAGTCAATGG	CACNA1A	ENSG00000141837	1.2072415920972	[]	[]	9	hSpCas9	negative selection	2613864
13506186	13506209	19	-	27260157	DLD1	viability	ACGAGATGCCGGCCCGCTACGGG	CACNA1A	ENSG00000141837	0.0469726111982057	[]	[]	3	hSpCas9	negative selection	2614530
13506054	13506077	19	-	27260157	DLD1	viability	AGTCAATGGCGCAGAGAGCGCGG	CACNA1A	ENSG00000141837	0.586191143301565	[]	[]	8	hSpCas9	negative selection	2615917
13506124	13506147	19	-	27260157	DLD1	viability	AGCGGAGGCGGGCGAGGAGCCGG	CACNA1A	ENSG00000141837	-1.24032889471229	[]	[]	-7	hSpCas9	negative selection	2616698
13455154	13455177	19	-	27260157	DLD1	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.539062350796396	[]	[]	-4	hSpCas9	negative selection	2618343
13506002	13506025	19	+	27260157	DLD1	viability	TAACCGTGAGGCAGTTCTGTCGG	CACNA1A	ENSG00000141837	-0.448256073652015	[]	[]	-4	hSpCas9	negative selection	2621433
13506047	13506070	19	-	27260157	DLD1	viability	GGCGCAGAGAGCGCGGACCATGG	CACNA1A	ENSG00000141837	0.189944443591156	[]	[]	3	hSpCas9	negative selection	2623391
13455164	13455187	19	+	27260157	DLD1	viability	GACGATGCAATTCGCTATGATGG	CACNA1A	ENSG00000141837	0.431382838845427	[]	[]	7	hSpCas9	negative selection	2623466
13506184	13506207	19	-	27260157	HT1080	viability	GAGATGCCGGCCCGCTACGGGGG	CACNA1A	ENSG00000141837	-0.462447385548743	[]	[]	-7	hSpCas9	negative selection	2652369
13452916	13452939	19	+	27260157	HT1080	viability	TCCTCAAGTAGGAGCCTTTGTGG	CACNA1A	ENSG00000141837	-0.42344624967954	[]	[]	-7	hSpCas9	negative selection	2654296
13506141	13506164	19	+	27260157	HT1080	viability	TCCGCTGCCCACGACCACCCCGG	CACNA1A	ENSG00000141837	-0.0163442799544911	[]	[]	0	hSpCas9	negative selection	2656676
13506007	13506030	19	+	27260157	HT1080	viability	GTGAGGCAGTTCTGTCGGACGGG	CACNA1A	ENSG00000141837	0.924117974549543	[]	[]	7	hSpCas9	negative selection	2658332
13506197	13506220	19	-	27260157	HT1080	viability	CCGCTTCGGAGACGAGATGCCGG	CACNA1A	ENSG00000141837	0.366885916244697	[]	[]	3	hSpCas9	negative selection	2659442
13506197	13506220	19	+	27260157	HT1080	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.0561596387070882	[]	[]	0	hSpCas9	negative selection	2659707
13505990	13506013	19	+	27260157	HT1080	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.0680511073775567	[]	[]	0	hSpCas9	negative selection	2661766
13506211	13506234	19	-	27260157	HT1080	viability	CTTTGCAGAATGGCCCGCTTCGG	CACNA1A	ENSG00000141837	-0.124228937165155	[]	[]	0	hSpCas9	negative selection	2681493
13506135	13506158	19	-	27260157	HT1080	viability	TGGTCGTGGGCAGCGGAGGCGGG	CACNA1A	ENSG00000141837	0.511677417436461	[]	[]	4	hSpCas9	negative selection	2684401
13505997	13506020	19	-	27260157	HT1080	viability	AGAACTGCCTCACGGTTAACCGG	CACNA1A	ENSG00000141837	0.153529178518587	[]	[]	1	hSpCas9	negative selection	2689259
13506078	13506101	19	+	27260157	HT1080	viability	CTTGTACATCCTTTGCGCCCCGG	CACNA1A	ENSG00000141837	-1.1842578181061	[]	[]	-8	hSpCas9	negative selection	2689863
13506068	13506091	19	-	27260157	HT1080	viability	AAGGATGTACAAGCAGTCAATGG	CACNA1A	ENSG00000141837	0.558743632594158	[]	[]	5	hSpCas9	negative selection	2689994
13506186	13506209	19	-	27260157	HT1080	viability	ACGAGATGCCGGCCCGCTACGGG	CACNA1A	ENSG00000141837	0.11116175632415	[]	[]	1	hSpCas9	negative selection	2690660
13506054	13506077	19	-	27260157	HT1080	viability	AGTCAATGGCGCAGAGAGCGCGG	CACNA1A	ENSG00000141837	0.602605906203354	[]	[]	5	hSpCas9	negative selection	2692047
13506124	13506147	19	-	27260157	HT1080	viability	AGCGGAGGCGGGCGAGGAGCCGG	CACNA1A	ENSG00000141837	-1.18574411271895	[]	[]	-8	hSpCas9	negative selection	2692828
13455154	13455177	19	-	27260157	HT1080	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.636217876501986	[]	[]	-8	hSpCas9	negative selection	2694473
13506002	13506025	19	+	27260157	HT1080	viability	TAACCGTGAGGCAGTTCTGTCGG	CACNA1A	ENSG00000141837	-0.709819395977171	[]	[]	-8	hSpCas9	negative selection	2697563
13506047	13506070	19	-	27260157	HT1080	viability	GGCGCAGAGAGCGCGGACCATGG	CACNA1A	ENSG00000141837	0.341734435733903	[]	[]	3	hSpCas9	negative selection	2699521
13455164	13455187	19	+	27260157	HT1080	viability	GACGATGCAATTCGCTATGATGG	CACNA1A	ENSG00000141837	0.881495164119188	[]	[]	7	hSpCas9	negative selection	2699596
13506184	13506207	19	-	27260157	MKN45	viability	GAGATGCCGGCCCGCTACGGGGG	CACNA1A	ENSG00000141837	-0.329057684135184	[]	[]	-1	hSpCas9	negative selection	2728499
13452916	13452939	19	+	27260157	MKN45	viability	TCCTCAAGTAGGAGCCTTTGTGG	CACNA1A	ENSG00000141837	-0.311160390938222	[]	[]	-1	hSpCas9	negative selection	2730426
13506141	13506164	19	+	27260157	MKN45	viability	TCCGCTGCCCACGACCACCCCGG	CACNA1A	ENSG00000141837	0.0171927066237099	[]	[]	0	hSpCas9	negative selection	2732806
13506007	13506030	19	+	27260157	MKN45	viability	GTGAGGCAGTTCTGTCGGACGGG	CACNA1A	ENSG00000141837	-0.241741700357489	[]	[]	-1	hSpCas9	negative selection	2734462
13506197	13506220	19	-	27260157	MKN45	viability	CCGCTTCGGAGACGAGATGCCGG	CACNA1A	ENSG00000141837	0.284337069975502	[]	[]	5	hSpCas9	negative selection	2735572
13506197	13506220	19	+	27260157	MKN45	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.0880830007712311	[]	[]	0	hSpCas9	negative selection	2735837
13505990	13506013	19	+	27260157	MKN45	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.348283004268356	[]	[]	-1	hSpCas9	negative selection	2737896
13506211	13506234	19	-	27260157	MKN45	viability	CTTTGCAGAATGGCCCGCTTCGG	CACNA1A	ENSG00000141837	-0.0331199520721157	[]	[]	0	hSpCas9	negative selection	2757623
13506135	13506158	19	-	27260157	MKN45	viability	TGGTCGTGGGCAGCGGAGGCGGG	CACNA1A	ENSG00000141837	0.0676452275204278	[]	[]	0	hSpCas9	negative selection	2760531
13505997	13506020	19	-	27260157	MKN45	viability	AGAACTGCCTCACGGTTAACCGG	CACNA1A	ENSG00000141837	-0.412203136226758	[]	[]	-6	hSpCas9	negative selection	2765389
13506078	13506101	19	+	27260157	MKN45	viability	CTTGTACATCCTTTGCGCCCCGG	CACNA1A	ENSG00000141837	-0.942438038807779	[]	[]	-7	hSpCas9	negative selection	2765993
13506068	13506091	19	-	27260157	MKN45	viability	AAGGATGTACAAGCAGTCAATGG	CACNA1A	ENSG00000141837	-0.093711212460664	[]	[]	0	hSpCas9	negative selection	2766124
13506186	13506209	19	-	27260157	MKN45	viability	ACGAGATGCCGGCCCGCTACGGG	CACNA1A	ENSG00000141837	0.527650641431495	[]	[]	6	hSpCas9	negative selection	2766790
13506054	13506077	19	-	27260157	MKN45	viability	AGTCAATGGCGCAGAGAGCGCGG	CACNA1A	ENSG00000141837	0.824711257568548	[]	[]	8	hSpCas9	negative selection	2768177
13506124	13506147	19	-	27260157	MKN45	viability	AGCGGAGGCGGGCGAGGAGCCGG	CACNA1A	ENSG00000141837	-1.56524379691548	[]	[]	-9	hSpCas9	negative selection	2768958
13455154	13455177	19	-	27260157	MKN45	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.12128694541117	[]	[]	-8	hSpCas9	negative selection	2770603
13506002	13506025	19	+	27260157	MKN45	viability	TAACCGTGAGGCAGTTCTGTCGG	CACNA1A	ENSG00000141837	-0.52725165890656	[]	[]	-6	hSpCas9	negative selection	2773693
13506047	13506070	19	-	27260157	MKN45	viability	GGCGCAGAGAGCGCGGACCATGG	CACNA1A	ENSG00000141837	-0.393284245204702	[]	[]	-1	hSpCas9	negative selection	2775651
13455164	13455187	19	+	27260157	MKN45	viability	GACGATGCAATTCGCTATGATGG	CACNA1A	ENSG00000141837	-0.560989717825148	[]	[]	-6	hSpCas9	negative selection	2775726
13506184	13506207	19	-	27260157	RKO	viability	GAGATGCCGGCCCGCTACGGGGG	CACNA1A	ENSG00000141837	0.363344047545909	[]	[]	2	hSpCas9	negative selection	2804629
13452916	13452939	19	+	27260157	RKO	viability	TCCTCAAGTAGGAGCCTTTGTGG	CACNA1A	ENSG00000141837	-1.69563867573048	[]	[]	-9	hSpCas9	negative selection	2806556
13506141	13506164	19	+	27260157	RKO	viability	TCCGCTGCCCACGACCACCCCGG	CACNA1A	ENSG00000141837	-0.311175073848396	[]	[]	-6	hSpCas9	negative selection	2808936
13506007	13506030	19	+	27260157	RKO	viability	GTGAGGCAGTTCTGTCGGACGGG	CACNA1A	ENSG00000141837	0.797821803372616	[]	[]	8	hSpCas9	negative selection	2810592
13506197	13506220	19	-	27260157	RKO	viability	CCGCTTCGGAGACGAGATGCCGG	CACNA1A	ENSG00000141837	0.515648586177786	[]	[]	2	hSpCas9	negative selection	2811702
13506197	13506220	19	+	27260157	RKO	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.690318273788493	[]	[]	-7	hSpCas9	negative selection	2811967
13505990	13506013	19	+	27260157	RKO	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.405663113654736	[]	[]	2	hSpCas9	negative selection	2814026
13506211	13506234	19	-	27260157	RKO	viability	CTTTGCAGAATGGCCCGCTTCGG	CACNA1A	ENSG00000141837	0.37681280948811	[]	[]	2	hSpCas9	negative selection	2833753
13506135	13506158	19	-	27260157	RKO	viability	TGGTCGTGGGCAGCGGAGGCGGG	CACNA1A	ENSG00000141837	0.276492811979832	[]	[]	1	hSpCas9	negative selection	2836661
13505997	13506020	19	-	27260157	RKO	viability	AGAACTGCCTCACGGTTAACCGG	CACNA1A	ENSG00000141837	1.02986014897879	[]	[]	9	hSpCas9	negative selection	2841519
13506078	13506101	19	+	27260157	RKO	viability	CTTGTACATCCTTTGCGCCCCGG	CACNA1A	ENSG00000141837	-0.645970925516751	[]	[]	-7	hSpCas9	negative selection	2842123
13506068	13506091	19	-	27260157	RKO	viability	AAGGATGTACAAGCAGTCAATGG	CACNA1A	ENSG00000141837	0.909912230222643	[]	[]	8	hSpCas9	negative selection	2842254
13506186	13506209	19	-	27260157	RKO	viability	ACGAGATGCCGGCCCGCTACGGG	CACNA1A	ENSG00000141837	0.576318891102861	[]	[]	3	hSpCas9	negative selection	2842920
13506054	13506077	19	-	27260157	RKO	viability	AGTCAATGGCGCAGAGAGCGCGG	CACNA1A	ENSG00000141837	1.01299737412865	[]	[]	9	hSpCas9	negative selection	2844307
13506124	13506147	19	-	27260157	RKO	viability	AGCGGAGGCGGGCGAGGAGCCGG	CACNA1A	ENSG00000141837	-1.83258179847376	[]	[]	-9	hSpCas9	negative selection	2845088
13455154	13455177	19	-	27260157	RKO	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.0249628735414272	[]	[]	0	hSpCas9	negative selection	2846733
13506002	13506025	19	+	27260157	RKO	viability	TAACCGTGAGGCAGTTCTGTCGG	CACNA1A	ENSG00000141837	-0.566200630980002	[]	[]	-7	hSpCas9	negative selection	2849823
13506047	13506070	19	-	27260157	RKO	viability	GGCGCAGAGAGCGCGGACCATGG	CACNA1A	ENSG00000141837	-0.570711348139295	[]	[]	-7	hSpCas9	negative selection	2851781
13455164	13455187	19	+	27260157	RKO	viability	GACGATGCAATTCGCTATGATGG	CACNA1A	ENSG00000141837	-0.326117595110803	[]	[]	-6	hSpCas9	negative selection	2851856
13506184	13506207	19	-	27260157	SF268	viability	GAGATGCCGGCCCGCTACGGGGG	CACNA1A	ENSG00000141837	-0.880260315577251	[]	[]	-6	hSpCas9	negative selection	2880759
13452916	13452939	19	+	27260157	SF268	viability	TCCTCAAGTAGGAGCCTTTGTGG	CACNA1A	ENSG00000141837	-0.404334021384292	[]	[]	-3	hSpCas9	negative selection	2882686
13506141	13506164	19	+	27260157	SF268	viability	TCCGCTGCCCACGACCACCCCGG	CACNA1A	ENSG00000141837	0.161491991288648	[]	[]	0	hSpCas9	negative selection	2885066
13506007	13506030	19	+	27260157	SF268	viability	GTGAGGCAGTTCTGTCGGACGGG	CACNA1A	ENSG00000141837	-0.0161493568030451	[]	[]	0	hSpCas9	negative selection	2886722
13506197	13506220	19	-	27260157	SF268	viability	CCGCTTCGGAGACGAGATGCCGG	CACNA1A	ENSG00000141837	0.452628193019533	[]	[]	7	hSpCas9	negative selection	2887832
13506197	13506220	19	+	27260157	SF268	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-1.11446716841411	[]	[]	-7	hSpCas9	negative selection	2888097
13505990	13506013	19	+	27260157	SF268	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.321944669325646	[]	[]	-3	hSpCas9	negative selection	2890156
13506211	13506234	19	-	27260157	SF268	viability	CTTTGCAGAATGGCCCGCTTCGG	CACNA1A	ENSG00000141837	0.0343984784484554	[]	[]	0	hSpCas9	negative selection	2909883
13506135	13506158	19	-	27260157	SF268	viability	TGGTCGTGGGCAGCGGAGGCGGG	CACNA1A	ENSG00000141837	0.0653309514016488	[]	[]	0	hSpCas9	negative selection	2912791
13505997	13506020	19	-	27260157	SF268	viability	AGAACTGCCTCACGGTTAACCGG	CACNA1A	ENSG00000141837	0.302017889323147	[]	[]	4	hSpCas9	negative selection	2917649
13506078	13506101	19	+	27260157	SF268	viability	CTTGTACATCCTTTGCGCCCCGG	CACNA1A	ENSG00000141837	-1.18135082485918	[]	[]	-7	hSpCas9	negative selection	2918253
13506068	13506091	19	-	27260157	SF268	viability	AAGGATGTACAAGCAGTCAATGG	CACNA1A	ENSG00000141837	0.116720552780513	[]	[]	0	hSpCas9	negative selection	2918384
13506186	13506209	19	-	27260157	SF268	viability	ACGAGATGCCGGCCCGCTACGGG	CACNA1A	ENSG00000141837	0.0844271597781518	[]	[]	0	hSpCas9	negative selection	2919050
13506054	13506077	19	-	27260157	SF268	viability	AGTCAATGGCGCAGAGAGCGCGG	CACNA1A	ENSG00000141837	0.513712501485492	[]	[]	7	hSpCas9	negative selection	2920437
13506124	13506147	19	-	27260157	SF268	viability	AGCGGAGGCGGGCGAGGAGCCGG	CACNA1A	ENSG00000141837	-1.44355874349678	[]	[]	-8	hSpCas9	negative selection	2921218
13455154	13455177	19	-	27260157	SF268	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.38224831652571	[]	[]	-7	hSpCas9	negative selection	2922863
13506002	13506025	19	+	27260157	SF268	viability	TAACCGTGAGGCAGTTCTGTCGG	CACNA1A	ENSG00000141837	-0.521462766209192	[]	[]	-4	hSpCas9	negative selection	2925953
13506047	13506070	19	-	27260157	SF268	viability	GGCGCAGAGAGCGCGGACCATGG	CACNA1A	ENSG00000141837	0.0801590187474518	[]	[]	0	hSpCas9	negative selection	2927911
13455164	13455187	19	+	27260157	SF268	viability	GACGATGCAATTCGCTATGATGG	CACNA1A	ENSG00000141837	0.0286050506250956	[]	[]	0	hSpCas9	negative selection	2927986
13332905	13332928	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGAGGTGATCCTCGCCGAGG	CACNA1A	ENSG00000141837	-0.4854493329670103	[3,3]	[3,0]	-6	hSpCas9	positive selection	2975866
13286955	13286978	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTTCCTCAGAGAGAACCAGGG	CACNA1A	ENSG00000141837	0.14761607741448063	[2,2]	[4,0]	3	hSpCas9	positive selection	2975867
13506145	13506168	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCCCACGACCACCCCGGCGG	CACNA1A	ENSG00000141837	0.09101459053686901	[3,3]	[3,2]	2	hSpCas9	positive selection	2975868
13334439	13334462	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGCTTCAGAAAAGCCCGCCGG	CACNA1A	ENSG00000141837	0.08337401375524983	[2,3]	[3,1]	1	hSpCas9	positive selection	2975869
13332905	13332928	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGAGGTGATCCTCGCCGAGG	CACNA1A	ENSG00000141837	-0.3302388387222991	[3,3]	[3,0]	-5	hSpCas9	positive selection	3043724
13286955	13286978	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTTCCTCAGAGAGAACCAGGG	CACNA1A	ENSG00000141837	-0.4292149276037075	[2,2]	[2,0]	-6	hSpCas9	positive selection	3043725
13506145	13506168	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCCCACGACCACCCCGGCGG	CACNA1A	ENSG00000141837	0.0003141243675081895	[3,3]	[3,1]	0	hSpCas9	positive selection	3043726
13334439	13334462	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGCTTCAGAAAAGCCCGCCGG	CACNA1A	ENSG00000141837	0.38766459976199263	[2,2]	[2,2]	6	hSpCas9	positive selection	3043727
13506197	13506220		+	24336571	A375	resistance to PLX after 7 days	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.007652741961757581	[5,6]	[6,6]	0	hSpCas9	positive selection	3160167
13506005	13506028		-	24336571	A375	resistance to PLX after 7 days	CGTCCGACAGAACTGCCTCACGG	CACNA1A	ENSG00000141837	0.11067840801800632	[35,33]	[41,32]	3	hSpCas9	positive selection	3160168
13455154	13455177		-	24336571	A375	resistance to PLX after 7 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.2383312978166811	[14,11]	[15,15]	7	hSpCas9	positive selection	3160169
13455167	13455190		+	24336571	A375	resistance to PLX after 7 days	GATGCAATTCGCTATGATGGTGG	CACNA1A	ENSG00000141837	-0.001258616116808553	[16,12]	[14,13]	0	hSpCas9	positive selection	3160171
13506197	13506220		+	24336571	A375	resistance to PLX after 14 days	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.6378025932113305	[6,9]	[1,1]	-7	hSpCas9	positive selection	3217960
13506005	13506028		-	24336571	A375	resistance to PLX after 14 days	CGTCCGACAGAACTGCCTCACGG	CACNA1A	ENSG00000141837	0.637090094004406	[19,29]	[18,16]	6	hSpCas9	positive selection	3217961
13455154	13455177		-	24336571	A375	resistance to PLX after 14 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.43228129278071065	[15,8]	[8,5]	4	hSpCas9	positive selection	3217962
13455167	13455190		+	24336571	A375	resistance to PLX after 14 days	GATGCAATTCGCTATGATGGTGG	CACNA1A	ENSG00000141837	-0.37476153248027877	[18,11]	[4,5]	-4	hSpCas9	positive selection	3217964
13506197	13506220		+	24336571	A375	viability after 7 days	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.7952857889837733	[12]	[5,6]	-8	hSpCas9	negative selection	3275753
13506005	13506028		-	24336571	A375	viability after 7 days	CGTCCGACAGAACTGCCTCACGG	CACNA1A	ENSG00000141837	0.16889961451282054	[32]	[35,33]	2	hSpCas9	negative selection	3275754
13455154	13455177		-	24336571	A375	viability after 7 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.878609769206792	[26]	[14,11]	-8	hSpCas9	negative selection	3275755
13455167	13455190		+	24336571	A375	viability after 7 days	GATGCAATTCGCTATGATGGTGG	CACNA1A	ENSG00000141837	-0.08103772535786946	[16]	[16,12]	-1	hSpCas9	negative selection	3275757
13506197	13506220		+	24336571	A375	viability after 14 days	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.5433403514722193	[12]	[6,9]	-6	hSpCas9	negative selection	3333546
13506005	13506028		-	24336571	A375	viability after 14 days	CGTCCGACAGAACTGCCTCACGG	CACNA1A	ENSG00000141837	-0.2838306237108621	[32]	[19,29]	-3	hSpCas9	negative selection	3333547
13455154	13455177		-	24336571	A375	viability after 14 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.0065183088053749	[26]	[15,8]	-8	hSpCas9	negative selection	3333548
13455167	13455190		+	24336571	A375	viability after 14 days	GATGCAATTCGCTATGATGGTGG	CACNA1A	ENSG00000141837	0.026549162458310183	[16]	[18,11]	0	hSpCas9	negative selection	3333550
13455154	13455177	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	1.3751627017396932	[55,61]	[0,0]	6	hSpCas9	positive selection	3340711
13506197	13506220	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.9198063310751526	[60,100]	[0,0]	4	hSpCas9	positive selection	3340712
13505990	13506013	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.3099900901189069	[109,136]	[0,0]	1	hSpCas9	positive selection	3340713
13455102	13455125	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	-0.3865299783288896	[399,399]	[1,1]	-2	hSpCas9	positive selection	3359964
13452917	13452940	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	1.148801754667666	[68,68]	[0,0]	5	hSpCas9	positive selection	3359965
13452990	13453013	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	-1.3792984090978138	[397,397]	[0,0]	-8	hSpCas9	positive selection	3359966
13332905	13332928	19	-	26780180	HT29	viability (Avana library 4 designs)	AGAAGAGGTGATCCTCGCCGAGG	CACNA1A	ENSG00000141837	1.40628031747869	[]	[]	5	hSpCas9	negative selection	3412141
13286955	13286978	19	-	26780180	HT29	viability (Avana library 4 designs)	GCCTTCCTCAGAGAGAACCAGGG	CACNA1A	ENSG00000141837	1.58097657299725	[]	[]	6	hSpCas9	negative selection	3412142
13506144	13506167	19	+	26780180	HT29	viability (Avana library 4 designs)	GCTGCCCACGACCACCCCGGCGG	CACNA1A	ENSG00000141837	0.558593360934979	[]	[]	2	hSpCas9	negative selection	3412143
13334438	13334461	19	+	26780180	HT29	viability (Avana library 4 designs)	TCAGCTTCAGAAAAGCCCGCCGG	CACNA1A	ENSG00000141837	0.285516586837315	[]	[]	1	hSpCas9	negative selection	3412144
13332905	13332928	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGAGGTGATCCTCGCCGAGG	CACNA1A	ENSG00000141837	-0.34240520144593	[]	[]	0	hSpCas9	negative selection	3487457
13334438	13334461	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCTTCAGAAAAGCCCGCCGG	CACNA1A	ENSG00000141837	1.46582138454043	[]	[]	2	hSpCas9	negative selection	3487458
13286955	13286978	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTTCCTCAGAGAGAACCAGGG	CACNA1A	ENSG00000141837	-2.81160096584451	[]	[]	-3	hSpCas9	negative selection	3487459
13506144	13506167	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCCCACGACCACCCCGGCGG	CACNA1A	ENSG00000141837	2.85146711044072	[]	[]	4	hSpCas9	negative selection	3487460
13452932	13452955	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.650616613029071	[]	[]	0	hSpCas9	negative selection	3487461
13330265	13330288	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGATCCTCAGCCTCTTCGGGG	CACNA1A	ENSG00000141837	6.97740505557225	[]	[]	9	hSpCas9	negative selection	3487462
13332905	13332928	19	-	26780180	A375	viability (Avana lentiGuide)	AGAAGAGGTGATCCTCGCCGAGG	CACNA1A	ENSG00000141837	1.47973405116145	[]	[]	1	hSpCas9	negative selection	3596116
13334438	13334461	19	+	26780180	A375	viability (Avana lentiGuide)	TCAGCTTCAGAAAAGCCCGCCGG	CACNA1A	ENSG00000141837	-3.05553972776233	[]	[]	-5	hSpCas9	negative selection	3596117
13286955	13286978	19	-	26780180	A375	viability (Avana lentiGuide)	GCCTTCCTCAGAGAGAACCAGGG	CACNA1A	ENSG00000141837	27.7044274306305	[]	[]	9	hSpCas9	negative selection	3596118
13506144	13506167	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGCCCACGACCACCCCGGCGG	CACNA1A	ENSG00000141837	-4.17513850546241	[]	[]	-7	hSpCas9	negative selection	3596119
13452932	13452955	19	+	26780180	A375	viability (Avana lentiGuide)	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-4.43154840743666	[]	[]	-7	hSpCas9	negative selection	3596120
13330265	13330288	19	+	26780180	A375	viability (Avana lentiGuide)	GCTGATCCTCAGCCTCTTCGGGG	CACNA1A	ENSG00000141837	-2.69324324198165	[]	[]	-5	hSpCas9	negative selection	3596121
13332905	13332928	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGAGGTGATCCTCGCCGAGG	CACNA1A	ENSG00000141837	-0.013105556281920505	[4]	[5,3]	0	hSpCas9	positive selection	3704775
13334438	13334461	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCTTCAGAAAAGCCCGCCGG	CACNA1A	ENSG00000141837	-0.8510316550388122	[4]	[2,0]	-8	hSpCas9	positive selection	3704776
13286955	13286978	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTTCCTCAGAGAGAACCAGGG	CACNA1A	ENSG00000141837	-0.681135273713054	[4]	[1,2]	-7	hSpCas9	positive selection	3704777
13506144	13506167	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCCCACGACCACCCCGGCGG	CACNA1A	ENSG00000141837	0.33648220311376015	[4]	[5,6]	8	hSpCas9	positive selection	3704778
13452932	13452955	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.005226950336644498	[4]	[4,4]	0	hSpCas9	positive selection	3704779
13330265	13330288	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGATCCTCAGCCTCTTCGGGG	CACNA1A	ENSG00000141837	0.37835446381177196	[4]	[6,6]	9	hSpCas9	positive selection	3704780
13332905	13332928	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGAGGTGATCCTCGCCGAGG	CACNA1A	ENSG00000141837	-0.4570894861780037	[5]	[1,3]	-5	hSpCas9	positive selection	3813382
13334438	13334461	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCTTCAGAAAAGCCCGCCGG	CACNA1A	ENSG00000141837	-0.5332971320904726	[4]	[2,2]	-6	hSpCas9	positive selection	3813383
13286955	13286978	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTTCCTCAGAGAGAACCAGGG	CACNA1A	ENSG00000141837	-1.584072310772152	[4]	[0,0]	-9	hSpCas9	positive selection	3813384
13506144	13506167	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCCCACGACCACCCCGGCGG	CACNA1A	ENSG00000141837	0.04664750110013128	[5]	[4,4]	1	hSpCas9	positive selection	3813385
13452932	13452955	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.0986898392004478	[4]	[3,3]	-1	hSpCas9	positive selection	3813386
13330265	13330288	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGATCCTCAGCCTCTTCGGGG	CACNA1A	ENSG00000141837	0.14838869108684732	[5]	[5,4]	3	hSpCas9	positive selection	3813387
13505990	13506013	19	+	26780180	A375	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	1.301989778099	[]	[]	7	hSpCas9	negative selection	3921682
13506197	13506220	19	+	26780180	A375	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	1.1050651679492	[]	[]	5	hSpCas9	negative selection	3921683
13455102	13455125	19	+	26780180	A375	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.507807727996883	[]	[]	1	hSpCas9	negative selection	3921684
13455154	13455177	19	-	26780180	A375	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	1.17167373530641	[]	[]	6	hSpCas9	negative selection	3921685
13452990	13453013	19	-	26780180	A375	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.830254162869227	[]	[]	3	hSpCas9	negative selection	3921686
13452917	13452940	19	-	26780180	A375	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	0.889500795341174	[]	[]	4	hSpCas9	negative selection	3921687
13505990	13506013	19	+	26780180	HT29	viability (GeCKOv2 library)	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	1.48547832670399	[]	[]	7	hSpCas9	negative selection	4029648
13506197	13506220	19	+	26780180	HT29	viability (GeCKOv2 library)	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.480224503106139	[]	[]	1	hSpCas9	negative selection	4029649
13455102	13455125	19	+	26780180	HT29	viability (GeCKOv2 library)	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.763445445209407	[]	[]	3	hSpCas9	negative selection	4029650
13455154	13455177	19	-	26780180	HT29	viability (GeCKOv2 library)	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	1.71345253261122	[]	[]	8	hSpCas9	negative selection	4029651
13452990	13453013	19	-	26780180	HT29	viability (GeCKOv2 library)	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.245621757251647	[]	[]	0	hSpCas9	negative selection	4029652
13452917	13452940	19	-	26780180	HT29	viability (GeCKOv2 library)	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	1.31553893027066	[]	[]	6	hSpCas9	negative selection	4029653
13506197	13506220	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.2551311902097323	[3]	[2,0]	-6	hSpCas9	positive selection	4188235
13506005	13506028	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTCCGACAGAACTGCCTCACGG	CACNA1A	ENSG00000141837	0.11924875634073656	[5]	[3,4]	3	hSpCas9	positive selection	4188236
13455154	13455177	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.10120830223967091	[3]	[2,2]	2	hSpCas9	positive selection	4188237
13455167	13455190	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATGCAATTCGCTATGATGGTGG	CACNA1A	ENSG00000141837	0.07394570641730878	[3]	[2,2]	2	hSpCas9	positive selection	4188239
13506197	13506220	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.0006718873770131042	[3]	[3,0,1,0]	0	hSpCas9	positive selection	4252257
13506005	13506028	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTCCGACAGAACTGCCTCACGG	CACNA1A	ENSG00000141837	0.9458186584450805	[5]	[3,2,4,4]	6	hSpCas9	positive selection	4252258
13455154	13455177	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.11140082135423456	[4]	[2,2,1,0]	-1	hSpCas9	positive selection	4252259
13455167	13455190	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATGCAATTCGCTATGATGGTGG	CACNA1A	ENSG00000141837	0.9199338686628769	[3]	[0,0,2,4]	6	hSpCas9	positive selection	4252261
13455154	13455177	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.5649756908544281	[2]	[0,0]	-8	hSpCas9	positive selection	4260575
13506197	13506220	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.19736319428651045	[2]	[2,0]	-4	hSpCas9	positive selection	4260576
13505990	13506013	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.004892534126033091	[2]	[2,1]	0	hSpCas9	positive selection	4260577
13455102	13455125	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.1351345590925322	[4]	[4,2]	2	hSpCas9	positive selection	4324856
13452917	13452940	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	0.1977359073814231	[1]	[1,1]	4	hSpCas9	positive selection	4324857
13452990	13453013	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.19224314105558604	[3]	[4,2]	4	hSpCas9	positive selection	4324858
13286671	13286693	19	-	27760321	OCIAML3	viability	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.15589489201276707	[525,373]	[301,499]	1	hSpCas9	negative selection	4385083
13298588	13298610	19	-	27760321	OCIAML3	viability	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.29834979685619123	[683,553]	[523,680]	3	hSpCas9	negative selection	4385084
13298926	13298948	19	+	27760321	OCIAML3	viability	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	0.2783690525445893	[638,639]	[503,744]	3	hSpCas9	negative selection	4385085
13299027	13299049	19	+	27760321	OCIAML3	viability	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	-0.06287440691121149	[825,650]	[485,631]	0	hSpCas9	negative selection	4385086
13371733	13371755	19	-	27760321	OCIAML3	viability	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	-0.01537378861127442	[569,526]	[354,514]	0	hSpCas9	negative selection	4385087
13286671	13286693	19	-	27760321	OCIAML2	viability	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.27739965234997527	[525,373]	[398,485]	3	hSpCas9	negative selection	4468546
13298588	13298610	19	-	27760321	OCIAML2	viability	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.4828500412876723	[683,553]	[582,844]	6	hSpCas9	negative selection	4468547
13298926	13298948	19	+	27760321	OCIAML2	viability	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	0.24285296173870052	[638,639]	[539,711]	3	hSpCas9	negative selection	4468548
13299027	13299049	19	+	27760321	OCIAML2	viability	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.07282668041714035	[825,650]	[496,791]	0	hSpCas9	negative selection	4468549
13371733	13371755	19	-	27760321	OCIAML2	viability	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	0.597774984212858	[569,526]	[652,695]	7	hSpCas9	negative selection	4468550
13286671	13286693	19	-	27760321	MV411	viability	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.8802311378364547	[525,373]	[798,152]	6	hSpCas9	negative selection	4552009
13298588	13298610	19	-	27760321	MV411	viability	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	-0.16906632553851292	[683,553]	[83,777]	-1	hSpCas9	negative selection	4552010
13298926	13298948	19	+	27760321	MV411	viability	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	-0.11724663322893175	[638,639]	[112,806]	-1	hSpCas9	negative selection	4552011
13299027	13299049	19	+	27760321	MV411	viability	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.34737362681492523	[825,650]	[635,585]	2	hSpCas9	negative selection	4552012
13371733	13371755	19	-	27760321	MV411	viability	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	-0.6896890234196749	[569,526]	[251,182]	-5	hSpCas9	negative selection	4552013
13286671	13286693	19	-	27760321	HL60	viability	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.4051709586359894	[525,373]	[568,388]	5	hSpCas9	negative selection	4635472
13298588	13298610	19	-	27760321	HL60	viability	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.07194205773495721	[683,553]	[500,557]	0	hSpCas9	negative selection	4635473
13298926	13298948	19	+	27760321	HL60	viability	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	0.2820456107143986	[638,639]	[713,555]	3	hSpCas9	negative selection	4635474
13299027	13299049	19	+	27760321	HL60	viability	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.17863841172917194	[825,650]	[541,822]	2	hSpCas9	negative selection	4635475
13371733	13371755	19	-	27760321	HL60	viability	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	-0.10832772505697497	[569,526]	[437,391]	-1	hSpCas9	negative selection	4635476
13286671	13286693	19	-	27760321	HT1080	viability	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	1.8057477388194516	[373,291]	[606,306]	8	hSpCas9	negative selection	4718935
13298588	13298610	19	-	27760321	HT1080	viability	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	-0.03278992888273197	[553,432]	[111,279]	0	hSpCas9	negative selection	4718936
13298926	13298948	19	+	27760321	HT1080	viability	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	1.6117732886867207	[639,499]	[757,623]	8	hSpCas9	negative selection	4718937
13299027	13299049	19	+	27760321	HT1080	viability	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.015745480974434956	[650,507]	[93,385]	0	hSpCas9	negative selection	4718938
13371733	13371755	19	-	27760321	HT1080	viability	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	0.0006612958061480434	[526,410]	[163,211]	0	hSpCas9	negative selection	4718939
13286671	13286693	19	-	27760321	HT29	viability after 7 days	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.5204944802757498	[373,291]	[698,613,542]	7	hSpCas9	negative selection	4802398
13298588	13298610	19	-	27760321	HT29	viability after 7 days	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.5106941712818581	[553,432]	[1085,687,960]	7	hSpCas9	negative selection	4802399
13298926	13298948	19	+	27760321	HT29	viability after 7 days	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	-0.06990238501940704	[639,499]	[883,690,549]	-1	hSpCas9	negative selection	4802400
13299027	13299049	19	+	27760321	HT29	viability after 7 days	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.40858279675054243	[650,507]	[799,1067,1067]	6	hSpCas9	negative selection	4802401
13371733	13371755	19	-	27760321	HT29	viability after 7 days	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	0.03861106017098953	[526,410]	[705,402,755]	0	hSpCas9	negative selection	4802402
13286671	13286693	19	-	27760321	HT29	viability after 25 days	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.5364300246225187	[373,291]	[446,659,554]	6	hSpCas9	negative selection	4885861
13298588	13298610	19	-	27760321	HT29	viability after 25 days	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.3461882100549799	[553,432]	[586,673,917]	3	hSpCas9	negative selection	4885862
13298926	13298948	19	+	27760321	HT29	viability after 25 days	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	0.4467876966999086	[639,499]	[890,557,1250]	5	hSpCas9	negative selection	4885863
13299027	13299049	19	+	27760321	HT29	viability after 25 days	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	-0.046186932906045364	[650,507]	[492,509,962]	0	hSpCas9	negative selection	4885864
13371733	13371755	19	-	27760321	HT29	viability after 25 days	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	-0.18875368837354642	[526,410]	[376,575,461]	-2	hSpCas9	negative selection	4885865
13286671	13286693	19	-	27760321	HT29	viability after 22 days	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.6490925966221842	[373,291]	[432,748,633]	7	hSpCas9	negative selection	4969324
13298588	13298610	19	-	27760321	HT29	viability after 22 days	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.5191606680923575	[553,432]	[637,988,830]	6	hSpCas9	negative selection	4969325
13298926	13298948	19	+	27760321	HT29	viability after 22 days	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	0.26971393142411537	[639,499]	[1028,657,688]	3	hSpCas9	negative selection	4969326
13299027	13299049	19	+	27760321	HT29	viability after 22 days	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.1805752944093304	[650,507]	[775,664,836]	1	hSpCas9	negative selection	4969327
13371733	13371755	19	-	27760321	HT29	viability after 22 days	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	0.13757804754933306	[526,410]	[334,683,778]	1	hSpCas9	negative selection	4969328
13286671	13286693	19	-	27760321	HT29	viability after 19 days	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.377133746185006	[373,291]	[413,562,497]	3	hSpCas9	negative selection	5052787
13298588	13298610	19	-	27760321	HT29	viability after 19 days	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.3169084860282886	[553,432]	[637,812,652]	3	hSpCas9	negative selection	5052788
13298926	13298948	19	+	27760321	HT29	viability after 19 days	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	-0.13174809258926834	[639,499]	[681,494,615]	-1	hSpCas9	negative selection	5052789
13299027	13299049	19	+	27760321	HT29	viability after 19 days	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.027087038342178404	[650,507]	[885,712,456]	0	hSpCas9	negative selection	5052790
13371733	13371755	19	-	27760321	HT29	viability after 19 days	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	-0.13539755868299347	[526,410]	[739,263,486]	-1	hSpCas9	negative selection	5052791
13286671	13286693	19	-	27760321	HT29	viability after 16 days	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.7790079656922159	[373,291]	[553,1051,292]	8	hSpCas9	negative selection	5136250
13298588	13298610	19	-	27760321	HT29	viability after 16 days	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.05746189705446303	[553,432]	[833,507,407]	0	hSpCas9	negative selection	5136251
13298926	13298948	19	+	27760321	HT29	viability after 16 days	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	0.1316203373367998	[639,499]	[989,485,652]	1	hSpCas9	negative selection	5136252
13299027	13299049	19	+	27760321	HT29	viability after 16 days	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.32896414834070176	[650,507]	[940,660,856]	3	hSpCas9	negative selection	5136253
13371733	13371755	19	-	27760321	HT29	viability after 16 days	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	0.41000736130319654	[526,410]	[616,535,934]	4	hSpCas9	negative selection	5136254
13286671	13286693	19	-	27760321	HT29	viability after 13 days	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.46343087641557285	[373,291]	[465,478,645]	6	hSpCas9	negative selection	5219713
13298588	13298610	19	-	27760321	HT29	viability after 13 days	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.38140187610622045	[553,432]	[960,549,726]	5	hSpCas9	negative selection	5219714
13298926	13298948	19	+	27760321	HT29	viability after 13 days	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	0.2865501860910079	[639,499]	[925,509,972]	3	hSpCas9	negative selection	5219715
13299027	13299049	19	+	27760321	HT29	viability after 13 days	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.08789334228253809	[650,507]	[1138,537,479]	1	hSpCas9	negative selection	5219716
13371733	13371755	19	-	27760321	HT29	viability after 13 days	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	0.08160098258179899	[526,410]	[721,535,474]	1	hSpCas9	negative selection	5219717
13286671	13286693	19	-	27760321	HT29	viability after 10 days	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	0.17473824602972057	[373,291]	[552,614,248]	2	hSpCas9	negative selection	5303176
13298588	13298610	19	-	27760321	HT29	viability after 10 days	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.5023306347805144	[553,432]	[911,865,840]	6	hSpCas9	negative selection	5303177
13298926	13298948	19	+	27760321	HT29	viability after 10 days	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	0.3237644183872034	[639,499]	[767,1121,790]	4	hSpCas9	negative selection	5303178
13299027	13299049	19	+	27760321	HT29	viability after 10 days	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	0.31180200816828085	[650,507]	[1109,800,782]	4	hSpCas9	negative selection	5303179
13371733	13371755	19	-	27760321	HT29	viability after 10 days	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	-0.022291484507824144	[526,410]	[657,547,523]	0	hSpCas9	negative selection	5303180
13286671	13286693	19	-	27760321	MOLM13	viability	CGCCGGACGCCCAACAACCCGG	CACNA1A	ENSG00000141837	2.45858637796968	[525,373]	[2324,576]	9	hSpCas9	negative selection	5386639
13298588	13298610	19	-	27760321	MOLM13	viability	CGCTCCAGCCACGTACGAGGGG	CACNA1A	ENSG00000141837	0.3631410654789834	[683,553]	[314,558]	2	hSpCas9	negative selection	5386640
13298926	13298948	19	+	27760321	MOLM13	viability	GGTCCGACTCGCGGCCGTAGGG	CACNA1A	ENSG00000141837	0.36058247635241925	[638,639]	[258,639]	2	hSpCas9	negative selection	5386641
13299027	13299049	19	+	27760321	MOLM13	viability	CGGGCCCGATCGTGGTAGCGGG	CACNA1A	ENSG00000141837	-0.20223406585341697	[825,650]	[536,208]	-1	hSpCas9	negative selection	5386642
13371733	13371755	19	-	27760321	MOLM13	viability	TTTGACCTACGGACGCTGAGGG	CACNA1A	ENSG00000141837	0.35663568537888346	[569,526]	[627,198]	2	hSpCas9	negative selection	5386643
13506087	13506110	19	-	27661255	K562	viability	GCGGGCAGCCCGGGGCGCAAAGG	CACNA1A	ENSG00000141837	0.20952015312907468	[219,261]	[202,237]	7	dCas9-KRAB	negative selection	5467677
13455154	13455177	19	-	27260156	BXPC3	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.19267313755014825	[319]	[281,232,284,384]	-4	hSpCas9	negative selection	5533035
13506197	13506220	19	+	27260156	BXPC3	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.00674256522030664	[342]	[358,247,350,489]	0	hSpCas9	negative selection	5533036
13505990	13506013	19	+	27260156	BXPC3	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.06690999029694555	[360]	[360,375,382,472]	1	hSpCas9	negative selection	5533037
13455102	13455125	19	+	27260156	BXPC3	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.2617210001298873	[1248]	[1569,1411,1466,1843]	6	hSpCas9	negative selection	5597316
13452917	13452940	19	-	27260156	BXPC3	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.6099037439015862	[194]	[87,161,112,178]	-8	hSpCas9	negative selection	5597317
13452990	13453013	19	-	27260156	BXPC3	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.0819679545026199	[623]	[613,713,749,686]	1	hSpCas9	negative selection	5597318
13455154	13455177	19	-	27260156	A673	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.22942543838730756	[319]	[306,342,336,319]	-5	hSpCas9	negative selection	5654286
13506197	13506220	19	+	27260156	A673	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.10655595923772099	[342]	[580,352,359,500]	2	hSpCas9	negative selection	5654287
13505990	13506013	19	+	27260156	A673	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.21323214819427422	[360]	[369,418,412,285]	-5	hSpCas9	negative selection	5654288
13455102	13455125	19	+	27260156	A673	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.08976701742700666	[1248]	[1812,1514,1483,1596]	2	hSpCas9	negative selection	5718567
13452917	13452940	19	-	27260156	A673	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.20529610663110498	[194]	[231,147,195,242]	-5	hSpCas9	negative selection	5718568
13452990	13453013	19	-	27260156	A673	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.11382038024205826	[623]	[924,770,766,791]	2	hSpCas9	negative selection	5718569
13455154	13455177	19	-	27260156	A375	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.43838622755463497	[319]	[281,252,222,333]	-6	hSpCas9	negative selection	5775537
13506197	13506220	19	+	27260156	A375	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.44747150542368275	[342]	[335,296,277,266]	-6	hSpCas9	negative selection	5775538
13505990	13506013	19	+	27260156	A375	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.15936520107732433	[360]	[453,268,469,639]	2	hSpCas9	negative selection	5775539
13455102	13455125	19	+	27260156	A375	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.32354346555725666	[1248]	[1734,2240,1640,1744]	5	hSpCas9	negative selection	5839818
13452917	13452940	19	-	27260156	A375	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.1424448519189656	[194]	[279,248,159,148]	-2	hSpCas9	negative selection	5839819
13452990	13453013	19	-	27260156	A375	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.5823613789571229	[623]	[851,1619,900,1062]	8	hSpCas9	negative selection	5839820
13455154	13455177	19	-	27260156	COLO741	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.48584494103552855	[319]	[291,287,294]	-8	hSpCas9	negative selection	5896788
13506197	13506220	19	+	27260156	COLO741	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.029664429543958093	[342]	[472,434,385]	0	hSpCas9	negative selection	5896789
13505990	13506013	19	+	27260156	COLO741	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.14209993468723053	[360]	[555,367,345]	-3	hSpCas9	negative selection	5896790
13455102	13455125	19	+	27260156	COLO741	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.0674388424270882	[1248]	[1883,1509,1638]	1	hSpCas9	negative selection	5961069
13452917	13452940	19	-	27260156	COLO741	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.2020539717993679	[194]	[230,237,183]	-4	hSpCas9	negative selection	5961070
13452990	13453013	19	-	27260156	COLO741	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.3101281782209259	[623]	[944,807,1190]	6	hSpCas9	negative selection	5961071
13455154	13455177	19	-	27260156	CAL120	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.5101544814419982	[319]	[952,451,357]	7	hSpCas9	negative selection	6018039
13506197	13506220	19	+	27260156	CAL120	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.04018235946243398	[342]	[410,279,617]	0	hSpCas9	negative selection	6018040
13505990	13506013	19	+	27260156	CAL120	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.18075917064579985	[360]	[563,540,431]	2	hSpCas9	negative selection	6018041
13455102	13455125	19	+	27260156	CAL120	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.2742779402236357	[1248]	[2421,1649,1651]	4	hSpCas9	negative selection	6082320
13452917	13452940	19	-	27260156	CAL120	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.26090245387235966	[194]	[208,172,225]	-4	hSpCas9	negative selection	6082321
13452990	13453013	19	-	27260156	CAL120	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.13580294683516342	[623]	[748,862,929]	2	hSpCas9	negative selection	6082322
13455154	13455177	19	-	27260156	CADOES1	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.8310922820522	[319]	[136,148,169,214]	-9	hSpCas9	negative selection	6139290
13506197	13506220	19	+	27260156	CADOES1	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.00734866937798434	[342]	[243,295,454,272]	0	hSpCas9	negative selection	6139291
13505990	13506013	19	+	27260156	CADOES1	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.13075178279542465	[360]	[179,379,488,423]	2	hSpCas9	negative selection	6139292
13455102	13455125	19	+	27260156	CADOES1	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.15693556514957652	[1248]	[1208,1242,1168,1569]	2	hSpCas9	negative selection	6203571
13452917	13452940	19	-	27260156	CADOES1	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.24511222063918137	[194]	[112,103,192,203]	-4	hSpCas9	negative selection	6203572
13452990	13453013	19	-	27260156	CADOES1	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.2990065407755386	[623]	[621,891,721,616]	5	hSpCas9	negative selection	6203573
13455154	13455177	19	-	27260156	EWS502	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.2686587749276076	[319]	[260,239,368,257]	-5	hSpCas9	negative selection	6260541
13506197	13506220	19	+	27260156	EWS502	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.14438657467541982	[342]	[313,352,272,376]	-3	hSpCas9	negative selection	6260542
13505990	13506013	19	+	27260156	EWS502	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.17551931987919073	[360]	[367,379,172,430]	-3	hSpCas9	negative selection	6260543
13455102	13455125	19	+	27260156	EWS502	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.3098015536100498	[1248]	[1575,1465,1553,1995]	5	hSpCas9	negative selection	6324822
13452917	13452940	19	-	27260156	EWS502	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	0.17078274459003362	[194]	[290,205,152,274]	3	hSpCas9	negative selection	6324823
13452990	13453013	19	-	27260156	EWS502	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.22357709082832428	[623]	[441,648,1093,961]	4	hSpCas9	negative selection	6324824
13455154	13455177	19	-	27260156	EW8	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.3325345083761745	[319]	[251,178,128,280]	-6	hSpCas9	negative selection	6381792
13506197	13506220	19	+	27260156	EW8	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.0486885829030369	[342]	[314,261,252,251]	-1	hSpCas9	negative selection	6381793
13505990	13506013	19	+	27260156	EW8	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.1897221113014917	[360]	[292,192,267,272]	-4	hSpCas9	negative selection	6381794
13455102	13455125	19	+	27260156	EW8	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.10854870821866758	[1248]	[1487,1107,844,1006]	2	hSpCas9	negative selection	6446073
13452917	13452940	19	-	27260156	EW8	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.1204791107677734	[194]	[108,100,202,153]	-2	hSpCas9	negative selection	6446074
13452990	13453013	19	-	27260156	EW8	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.35922264482927607	[623]	[812,715,533,567]	6	hSpCas9	negative selection	6446075
13455154	13455177	19	-	27260156	CORL105	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.48681919933573314	[319]	[254,282,232,291]	-7	hSpCas9	negative selection	6503043
13506197	13506220	19	+	27260156	CORL105	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.1201611694630984	[342]	[365,383,444,549]	2	hSpCas9	negative selection	6503044
13505990	13506013	19	+	27260156	CORL105	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.26239639353286603	[360]	[572,415,747,332]	5	hSpCas9	negative selection	6503045
13455102	13455125	19	+	27260156	CORL105	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	-0.0507834010460968	[1248]	[1342,1252,1556,1515]	-1	hSpCas9	negative selection	6567324
13452917	13452940	19	-	27260156	CORL105	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.3961220558864986	[194]	[234,136,249,86]	-6	hSpCas9	negative selection	6567325
13452990	13453013	19	-	27260156	CORL105	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.20749230912123545	[623]	[935,789,1042,640]	4	hSpCas9	negative selection	6567326
13455154	13455177	19	-	27260156	HS294T	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.32011837198723736	[319]	[70,59,170,97]	-4	hSpCas9	negative selection	6624294
13506197	13506220	19	+	27260156	HS294T	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.0026468024879693353	[342]	[96,128,128,188]	0	hSpCas9	negative selection	6624295
13505990	13506013	19	+	27260156	HS294T	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.24876366498128005	[360]	[113,124,105,125]	-3	hSpCas9	negative selection	6624296
13455102	13455125	19	+	27260156	HS294T	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.08162132540678702	[1248]	[435,430,616,579]	1	hSpCas9	negative selection	6688575
13452917	13452940	19	-	27260156	HS294T	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.3789236656041759	[194]	[17,56,75,89]	-5	hSpCas9	negative selection	6688576
13452990	13453013	19	-	27260156	HS294T	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.36165830514332337	[623]	[257,422,269,284]	5	hSpCas9	negative selection	6688577
13455154	13455177	19	-	27260156	HCC44	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.2853098218899873	[319]	[218,228,450,314]	-4	hSpCas9	negative selection	6745545
13506197	13506220	19	+	27260156	HCC44	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.3216018639263972	[342]	[550,471,676,282]	5	hSpCas9	negative selection	6745546
13505990	13506013	19	+	27260156	HCC44	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.3476528573500773	[360]	[621,452,386,604]	5	hSpCas9	negative selection	6745547
13455102	13455125	19	+	27260156	HCC44	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.2740524156862125	[1248]	[1649,1719,2211,1328]	4	hSpCas9	negative selection	6809826
13452917	13452940	19	-	27260156	HCC44	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.029216174145231477	[194]	[339,142,268,143]	0	hSpCas9	negative selection	6809827
13452990	13453013	19	-	27260156	HCC44	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.37026544390378485	[623]	[1141,728,1088,763]	6	hSpCas9	negative selection	6809828
13455154	13455177	19	-	27260156	G402	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.39525109357406507	[319]	[499,458,171,896]	5	hSpCas9	negative selection	6866796
13506197	13506220	19	+	27260156	G402	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.39243374982493373	[342]	[287,324,378,279]	-5	hSpCas9	negative selection	6866797
13505990	13506013	19	+	27260156	G402	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.15749016742809155	[360]	[328,538,569,503]	2	hSpCas9	negative selection	6866798
13455102	13455125	19	+	27260156	G402	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.14522830114445395	[1248]	[1373,1252,1799,2211]	1	hSpCas9	negative selection	6931077
13452917	13452940	19	-	27260156	G402	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.056615153990465794	[194]	[217,222,213,255]	0	hSpCas9	negative selection	6931078
13452990	13453013	19	-	27260156	G402	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.44410446084972305	[623]	[1250,1221,728,981]	5	hSpCas9	negative selection	6931079
13455154	13455177	19	-	27260156	L33	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.019866463692568392	[319]	[329,182,158,232]	0	hSpCas9	negative selection	6988047
13506197	13506220	19	+	27260156	L33	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.44728793919200655	[342]	[487,189,254,511]	8	hSpCas9	negative selection	6988048
13505990	13506013	19	+	27260156	L33	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.22326943609431246	[360]	[459,141,252,474]	5	hSpCas9	negative selection	6988049
13455102	13455125	19	+	27260156	L33	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	-0.26420942086103993	[1248]	[1243,399,615,954]	-6	hSpCas9	negative selection	7052328
13452917	13452940	19	-	27260156	L33	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.16295834736380166	[194]	[217,72,100,138]	-4	hSpCas9	negative selection	7052329
13452990	13453013	19	-	27260156	L33	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.19959847816283877	[623]	[724,289,432,743]	4	hSpCas9	negative selection	7052330
13455154	13455177	19	-	27260156	K562	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.0388345349870467	[319]	[271,95,148,53]	-8	hSpCas9	negative selection	7109298
13506197	13506220	19	+	27260156	K562	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.2915309380431731	[342]	[394,223,550,318]	3	hSpCas9	negative selection	7109299
13505990	13506013	19	+	27260156	K562	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.3608604547762216	[360]	[320,208,300,177]	-4	hSpCas9	negative selection	7109300
13455102	13455125	19	+	27260156	K562	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.37404622867786186	[1248]	[1616,1344,1457,1340]	5	hSpCas9	negative selection	7173579
13452917	13452940	19	-	27260156	K562	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-1.0925514681290205	[194]	[118,114,59,39]	-8	hSpCas9	negative selection	7173580
13452990	13453013	19	-	27260156	K562	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.7577387899325458	[623]	[1119,707,816,1081]	8	hSpCas9	negative selection	7173581
13455154	13455177	19	-	27260156	HT29	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.06971891929818108	[319]	[471,367,263,381]	-1	hSpCas9	negative selection	7230549
13506197	13506220	19	+	27260156	HT29	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.0025606108749548495	[342]	[517,519,362,292]	0	hSpCas9	negative selection	7230550
13505990	13506013	19	+	27260156	HT29	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.151637982135914	[360]	[468,392,425,305]	-3	hSpCas9	negative selection	7230551
13455102	13455125	19	+	27260156	HT29	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.2645966800624864	[1248]	[1921,1983,1800,1621]	5	hSpCas9	negative selection	7294830
13452917	13452940	19	-	27260156	HT29	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.086347792805614	[194]	[288,101,234,255]	-2	hSpCas9	negative selection	7294831
13452990	13453013	19	-	27260156	HT29	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.40157906597863297	[623]	[1209,1177,957,720]	7	hSpCas9	negative selection	7294832
13455154	13455177	19	-	27260156	MHHES1	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.11520352924277943	[319]	[465,624,342,196]	2	hSpCas9	negative selection	7351800
13506197	13506220	19	+	27260156	MHHES1	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.08688825474060685	[342]	[467,376,475,332]	1	hSpCas9	negative selection	7351801
13505990	13506013	19	+	27260156	MHHES1	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.022668623250953368	[360]	[422,519,400,288]	0	hSpCas9	negative selection	7351802
13455102	13455125	19	+	27260156	MHHES1	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.06052413715940408	[1248]	[1312,1691,1480,1373]	1	hSpCas9	negative selection	7416081
13452917	13452940	19	-	27260156	MHHES1	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.42603652826672156	[194]	[108,157,155,208]	-7	hSpCas9	negative selection	7416082
13452990	13453013	19	-	27260156	MHHES1	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.06856630605592301	[623]	[824,753,664,705]	1	hSpCas9	negative selection	7416083
13455154	13455177	19	-	27260156	MEWO	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.2550609374614653	[319]	[358,373,338]	5	hSpCas9	negative selection	7473051
13506197	13506220	19	+	27260156	MEWO	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.3991657408229714	[342]	[414,395,456]	8	hSpCas9	negative selection	7473052
13505990	13506013	19	+	27260156	MEWO	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.052385819319100635	[360]	[489,284,302]	1	hSpCas9	negative selection	7473053
13455102	13455125	19	+	27260156	MEWO	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.15389661025696832	[1248]	[1812,942,1244]	3	hSpCas9	negative selection	7537332
13452917	13452940	19	-	27260156	MEWO	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.07908531793797713	[194]	[172,198,145]	-2	hSpCas9	negative selection	7537333
13452990	13453013	19	-	27260156	MEWO	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.1847371828544891	[623]	[733,689,579]	4	hSpCas9	negative selection	7537334
13455154	13455177	19	-	27260156	LNCAPCLONEFGC	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.42160784938203755	[319]	[164,177,370,177]	-6	hSpCas9	negative selection	7594302
13506197	13506220	19	+	27260156	LNCAPCLONEFGC	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.14034097842515347	[342]	[416,203,535,248]	2	hSpCas9	negative selection	7594303
13505990	13506013	19	+	27260156	LNCAPCLONEFGC	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.32627677073171757	[360]	[347,500,477,317]	5	hSpCas9	negative selection	7594304
13455102	13455125	19	+	27260156	LNCAPCLONEFGC	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.4577275530679279	[1248]	[1422,1662,1683,1458]	7	hSpCas9	negative selection	7658583
13452917	13452940	19	-	27260156	LNCAPCLONEFGC	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.4798546021244705	[194]	[140,167,122,70]	-6	hSpCas9	negative selection	7658584
13452990	13453013	19	-	27260156	LNCAPCLONEFGC	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.44518810046099594	[623]	[637,804,957,704]	7	hSpCas9	negative selection	7658585
13455154	13455177	19	-	27260156	PANC0327	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.6084924018144653	[319]	[296,152,131,176]	-7	hSpCas9	negative selection	7715553
13506197	13506220	19	+	27260156	PANC0327	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.5682353363373697	[342]	[362,79,189,217]	-7	hSpCas9	negative selection	7715554
13505990	13506013	19	+	27260156	PANC0327	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.18736265137415403	[360]	[337,205,377,218]	-3	hSpCas9	negative selection	7715555
13455102	13455125	19	+	27260156	PANC0327	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.1674346040272805	[1248]	[1423,1352,940,1265]	2	hSpCas9	negative selection	7779834
13452917	13452940	19	-	27260156	PANC0327	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.1292747236223033	[194]	[129,189,139,166]	-2	hSpCas9	negative selection	7779835
13452990	13453013	19	-	27260156	PANC0327	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	-0.07179255596731654	[623]	[457,457,697,498]	-1	hSpCas9	negative selection	7779836
13455154	13455177	19	-	27260156	NCIH2009	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.04523818775706734	[319]	[515,296,583]	0	hSpCas9	negative selection	7836804
13506197	13506220	19	+	27260156	NCIH2009	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.36162522642753075	[342]	[783,639,454]	5	hSpCas9	negative selection	7836805
13505990	13506013	19	+	27260156	NCIH2009	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.2511787564699456	[360]	[752,602,473]	3	hSpCas9	negative selection	7836806
13455102	13455125	19	+	27260156	NCIH2009	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.08886173248018792	[1248]	[1849,1878,1833]	1	hSpCas9	negative selection	7901085
13452917	13452940	19	-	27260156	NCIH2009	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.06119644912240396	[194]	[322,325,144]	-1	hSpCas9	negative selection	7901086
13452990	13453013	19	-	27260156	NCIH2009	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.0822956370358987	[623]	[1195,834,791]	1	hSpCas9	negative selection	7901087
13455154	13455177	19	-	27260156	NCIH1373	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.9952401191504598	[319]	[230,129,135,62]	-7	hSpCas9	negative selection	7958055
13506197	13506220	19	+	27260156	NCIH1373	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.24275566363908163	[342]	[354,290,269,103]	-2	hSpCas9	negative selection	7958056
13505990	13506013	19	+	27260156	NCIH1373	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.04162629095532855	[360]	[244,473,319,158]	0	hSpCas9	negative selection	7958057
13455102	13455125	19	+	27260156	NCIH1373	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.06257772829886243	[1248]	[1351,931,2250,346]	0	hSpCas9	negative selection	8022336
13452917	13452940	19	-	27260156	NCIH1373	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-1.17980097234423	[194]	[74,83,110,29]	-8	hSpCas9	negative selection	8022337
13452990	13453013	19	-	27260156	NCIH1373	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.7544870805838446	[623]	[2086,470,819,416]	7	hSpCas9	negative selection	8022338
13455154	13455177	19	-	27260156	PATU8902	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.5914458949974428	[319]	[116,89,111,298]	-8	hSpCas9	negative selection	8079306
13506197	13506220	19	+	27260156	PATU8902	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-1.09241333284396	[342]	[156,391,100,284]	-7	hSpCas9	negative selection	8079307
13505990	13506013	19	+	27260156	PATU8902	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.015731184397270948	[360]	[413,280,670,584]	0	hSpCas9	negative selection	8079308
13455102	13455125	19	+	27260156	PATU8902	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	-0.2276832898381973	[1248]	[2001,1729,824,1545]	-2	hSpCas9	negative selection	8143587
13452917	13452940	19	-	27260156	PATU8902	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-1.1412604935631772	[194]	[67,135,27,306]	-7	hSpCas9	negative selection	8143588
13452990	13453013	19	-	27260156	PATU8902	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	-0.08106207024715789	[623]	[709,1033,701,872]	-1	hSpCas9	negative selection	8143589
13455154	13455177	19	-	27260156	PANC1	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.6787167759153094	[319]	[156,214,175,148]	-7	hSpCas9	negative selection	8200557
13506197	13506220	19	+	27260156	PANC1	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.20254124265590723	[342]	[214,319,290,214]	-3	hSpCas9	negative selection	8200558
13505990	13506013	19	+	27260156	PANC1	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.08398757397000012	[360]	[276,376,322,340]	1	hSpCas9	negative selection	8200559
13455102	13455125	19	+	27260156	PANC1	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.14511428803475934	[1248]	[1196,1803,1165,756]	2	hSpCas9	negative selection	8264838
13452917	13452940	19	-	27260156	PANC1	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.26798068500420835	[194]	[191,222,73,88]	-4	hSpCas9	negative selection	8264839
13452990	13453013	19	-	27260156	PANC1	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.4261370087739908	[623]	[509,963,1044,451]	7	hSpCas9	negative selection	8264840
13455154	13455177	19	-	27260156	PANC0813	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.1536120041462662	[319]	[363,354,290,342]	-3	hSpCas9	negative selection	8321808
13506197	13506220	19	+	27260156	PANC0813	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.3953240988240631	[342]	[491,590,534,498]	6	hSpCas9	negative selection	8321809
13505990	13506013	19	+	27260156	PANC0813	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.01932954354897304	[360]	[557,243,342,533]	0	hSpCas9	negative selection	8321810
13455102	13455125	19	+	27260156	PANC0813	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	-0.2559172890472061	[1248]	[1454,987,1419,1079]	-4	hSpCas9	negative selection	8386089
13452917	13452940	19	-	27260156	PANC0813	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.059783616243529236	[194]	[179,266,226,201]	-1	hSpCas9	negative selection	8386090
13452990	13453013	19	-	27260156	PANC0813	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.013943098865513037	[623]	[843,753,677,694]	0	hSpCas9	negative selection	8386091
13455154	13455177	19	-	27260156	RDES	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.948956289237693	[319]	[123,203,244,200]	-9	hSpCas9	negative selection	8443059
13506197	13506220	19	+	27260156	RDES	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.036000212838563805	[342]	[285,407,418,443]	0	hSpCas9	negative selection	8443060
13505990	13506013	19	+	27260156	RDES	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.006389500817722549	[360]	[331,433,379,543]	0	hSpCas9	negative selection	8443061
13455102	13455125	19	+	27260156	RDES	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.20950792265840823	[1248]	[1456,1472,1844,1925]	3	hSpCas9	negative selection	8507340
13452917	13452940	19	-	27260156	RDES	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.33490190814363285	[194]	[158,109,302,143]	-5	hSpCas9	negative selection	8507341
13452990	13453013	19	-	27260156	RDES	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.536366579148726	[623]	[880,907,1049,1393]	8	hSpCas9	negative selection	8507342
13455154	13455177	19	-	27260156	PC3	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-1.2307584088172865	[319]	[112,145,160,124]	-9	hSpCas9	negative selection	8564310
13506197	13506220	19	+	27260156	PC3	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.3543386834099457	[342]	[241,517,772,385]	7	hSpCas9	negative selection	8564311
13505990	13506013	19	+	27260156	PC3	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-4.25858488291575e-05	[360]	[135,394,521,529]	0	hSpCas9	negative selection	8564312
13455102	13455125	19	+	27260156	PC3	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.004203101052854485	[1248]	[700,1048,2606,1312]	0	hSpCas9	negative selection	8628591
13452917	13452940	19	-	27260156	PC3	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.1330661431541429	[194]	[85,253,238,174]	-3	hSpCas9	negative selection	8628592
13452990	13453013	19	-	27260156	PC3	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.3262291446777263	[623]	[606,651,1145,850]	7	hSpCas9	negative selection	8628593
13455154	13455177	19	-	27260156	PATU8988T	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.3180545074732335	[319]	[288,199,177,327]	-5	hSpCas9	negative selection	8685561
13506197	13506220	19	+	27260156	PATU8988T	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.10204398310214868	[342]	[476,277,240,230]	-2	hSpCas9	negative selection	8685562
13505990	13506013	19	+	27260156	PATU8988T	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.04095667487946941	[360]	[298,275,421,435]	0	hSpCas9	negative selection	8685563
13455102	13455125	19	+	27260156	PATU8988T	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.1798851125351435	[1248]	[1513,1718,1188,1056]	3	hSpCas9	negative selection	8749842
13452917	13452940	19	-	27260156	PATU8988T	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	0.09746710857984686	[194]	[305,223,89,188]	1	hSpCas9	negative selection	8749843
13452990	13453013	19	-	27260156	PATU8988T	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.29450424445813533	[623]	[860,791,554,758]	5	hSpCas9	negative selection	8749844
13455154	13455177	19	-	27260156	T47D	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.302224321709618	[319]	[369,266,274,300]	-6	hSpCas9	negative selection	8806812
13506197	13506220	19	+	27260156	T47D	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.2079057951675873	[342]	[478,392,438,543]	4	hSpCas9	negative selection	8806813
13505990	13506013	19	+	27260156	T47D	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.22115085972122356	[360]	[367,354,391,326]	-5	hSpCas9	negative selection	8806814
13455102	13455125	19	+	27260156	T47D	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.3354293054399258	[1248]	[1813,1791,1817,1925]	7	hSpCas9	negative selection	8871093
13452917	13452940	19	-	27260156	T47D	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.33244608905209705	[194]	[184,178,152,205]	-6	hSpCas9	negative selection	8871094
13452990	13453013	19	-	27260156	T47D	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.375874596701218	[623]	[863,886,985,1042]	7	hSpCas9	negative selection	8871095
13455154	13455177	19	-	27260156	SU8686	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.2872074248101496	[319]	[154,224,269,432]	-5	hSpCas9	negative selection	8928063
13506197	13506220	19	+	27260156	SU8686	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.21616182959980043	[342]	[316,380,458,439]	3	hSpCas9	negative selection	8928064
13505990	13506013	19	+	27260156	SU8686	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.04998146378072721	[360]	[370,217,469,456]	0	hSpCas9	negative selection	8928065
13455102	13455125	19	+	27260156	SU8686	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	-0.07939510989716103	[1248]	[1262,840,1427,1189]	-1	hSpCas9	negative selection	8992344
13452917	13452940	19	-	27260156	SU8686	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.3563317576618108	[194]	[150,94,121,258]	-5	hSpCas9	negative selection	8992345
13452990	13453013	19	-	27260156	SU8686	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.32461974459758997	[623]	[812,731,745,807]	5	hSpCas9	negative selection	8992346
13455154	13455177	19	-	27260156	SKES1	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.2681144816926886	[319]	[329,241,224,266]	-5	hSpCas9	negative selection	9049314
13506197	13506220	19	+	27260156	SKES1	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.020181919156990358	[342]	[418,400,357,235]	0	hSpCas9	negative selection	9049315
13505990	13506013	19	+	27260156	SKES1	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	0.0381016813882874	[360]	[503,304,414,272]	0	hSpCas9	negative selection	9049316
13455102	13455125	19	+	27260156	SKES1	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.07012147307085748	[1248]	[1414,1340,1220,1265]	1	hSpCas9	negative selection	9113595
13452917	13452940	19	-	27260156	SKES1	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.008446185819939833	[194]	[194,215,193,171]	0	hSpCas9	negative selection	9113596
13452990	13453013	19	-	27260156	SKES1	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.40938076065589885	[623]	[871,1003,871,603]	8	hSpCas9	negative selection	9113597
13455154	13455177	19	-	27260156	TOV112D	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.5786275184515866	[319]	[330,260,134,153]	-8	hSpCas9	negative selection	9170565
13506197	13506220	19	+	27260156	TOV112D	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.5341943088817568	[342]	[442,581,362,613]	8	hSpCas9	negative selection	9170566
13505990	13506013	19	+	27260156	TOV112D	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.2516254317309922	[360]	[369,376,299,193]	-5	hSpCas9	negative selection	9170567
13455102	13455125	19	+	27260156	TOV112D	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	-0.012336301620534229	[1248]	[1165,1138,1494,1130]	0	hSpCas9	negative selection	9234846
13452917	13452940	19	-	27260156	TOV112D	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	-0.3176751393112396	[194]	[100,278,152,119]	-6	hSpCas9	negative selection	9234847
13452990	13453013	19	-	27260156	TOV112D	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.34128561715715605	[623]	[752,1069,871,542]	6	hSpCas9	negative selection	9234848
13455154	13455177	19	-	27260156	TC71	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.1062436111663414	[319]	[302,336,326,306]	-3	hSpCas9	negative selection	9291816
13506197	13506220	19	+	27260156	TC71	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	0.4208835765497233	[342]	[559,399,430,583]	8	hSpCas9	negative selection	9291817
13505990	13506013	19	+	27260156	TC71	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.06798808444006499	[360]	[402,357,391,318]	-2	hSpCas9	negative selection	9291818
13455102	13455125	19	+	27260156	TC71	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.16536808862626828	[1248]	[1506,1476,1419,1610]	4	hSpCas9	negative selection	9356097
13452917	13452940	19	-	27260156	TC71	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	0.026351443108525663	[194]	[229,216,199,203]	0	hSpCas9	negative selection	9356098
13452990	13453013	19	-	27260156	TC71	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.03979819134063267	[623]	[664,799,587,701]	1	hSpCas9	negative selection	9356099
13455154	13455177	19	-	27260156	TC32	viability	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	-0.7968407377489939	[319]	[146,85,340,174]	-9	hSpCas9	negative selection	9413067
13506197	13506220	19	+	27260156	TC32	viability	CCGGCATCTCGTCTCCGAAGCGG	CACNA1A	ENSG00000141837	-0.1722444049727324	[342]	[307,158,347,373]	-3	hSpCas9	negative selection	9413068
13505990	13506013	19	+	27260156	TC32	viability	AGAGAGACCGGTTAACCGTGAGG	CACNA1A	ENSG00000141837	-0.12587524002534028	[360]	[226,260,459,333]	-2	hSpCas9	negative selection	9413069
13455102	13455125	19	+	27260156	TC32	viability	CTCACCAGCCGTTCAGACATCGG	CACNA1A	ENSG00000141837	0.1648121317307416	[1248]	[1085,1002,1714,1615]	3	hSpCas9	negative selection	9477348
13452917	13452940	19	-	27260156	TC32	viability	TCCACAAAGGCTCCTACTTGAGG	CACNA1A	ENSG00000141837	0.09968422475657035	[194]	[191,217,197,153]	1	hSpCas9	negative selection	9477349
13452990	13453013	19	-	27260156	TC32	viability	GACACAGAACCATACTTCATTGG	CACNA1A	ENSG00000141837	0.31626660990240624	[623]	[666,563,931,824]	5	hSpCas9	negative selection	9477350
13359751	13359774	19	+	27869803	HPAFII	viability after 27 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	0.03002772334652115	[209]	[85,134,NaN]	0	hSpCas9	negative selection	9565807
13365406	13365429	19	+	27869803	HPAFII	viability after 27 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.357750486848088	[344]	[182,106,NaN]	-3	hSpCas9	negative selection	9565808
13371757	13371780	19	-	27869803	HPAFII	viability after 27 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-1.2967781615286398	[177]	[18,53,NaN]	-7	hSpCas9	negative selection	9565809
13452932	13452955	19	+	27869803	HPAFII	viability after 27 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.2453802031911334	[172]	[91,63,NaN]	-2	hSpCas9	negative selection	9565810
13455154	13455177	19	-	27869803	HPAFII	viability after 27 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.6948801927991916	[82]	[98,46,NaN]	5	hSpCas9	negative selection	9565812
13505966	13505989	19	+	27869803	HPAFII	viability after 27 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	1.5076558694840636	[456]	[692,674,NaN]	9	hSpCas9	negative selection	9565816
13359751	13359774	19	+	27869803	HPAFII	viability after 15 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	0.06663566460797535	[209]	[363,156,NaN]	0	hSpCas9	negative selection	9648256
13365406	13365429	19	+	27869803	HPAFII	viability after 15 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.457951135894505	[344]	[301,249,NaN]	-5	hSpCas9	negative selection	9648257
13371757	13371780	19	-	27869803	HPAFII	viability after 15 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-1.3147761341537803	[177]	[87,69,NaN]	-8	hSpCas9	negative selection	9648258
13452932	13452955	19	+	27869803	HPAFII	viability after 15 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.35180142731596387	[172]	[260,73,NaN]	-4	hSpCas9	negative selection	9648259
13455154	13455177	19	-	27869803	HPAFII	viability after 15 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.3690008922561552	[82]	[129,105,NaN]	4	hSpCas9	negative selection	9648261
13505966	13505989	19	+	27869803	HPAFII	viability after 15 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	1.4213050139747425	[456]	[1558,1163,NaN]	9	hSpCas9	negative selection	9648265
13359751	13359774	19	+	27869803	ASPC1	viability after 36 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	0.5853624054528066	[458]	[464,299,32]	6	hSpCas9	negative selection	9730705
13365406	13365429	19	+	27869803	ASPC1	viability after 36 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	0.16434304946615774	[1160]	[326,721,325]	1	hSpCas9	negative selection	9730706
13371757	13371780	19	-	27869803	ASPC1	viability after 36 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-1.365406108558581	[494]	[129,89,3]	-8	hSpCas9	negative selection	9730707
13452932	13452955	19	+	27869803	ASPC1	viability after 36 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-1.0385210337278286	[338]	[68,73,35]	-7	hSpCas9	negative selection	9730708
13455154	13455177	19	-	27869803	ASPC1	viability after 36 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.35285486241787933	[266]	[86,107,148]	3	hSpCas9	negative selection	9730710
13505966	13505989	19	+	27869803	ASPC1	viability after 36 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.5069544489185349	[1385]	[621,998,478]	5	hSpCas9	negative selection	9730714
13359751	13359774	19	+	27869803	PATU8988S	viability after 35 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.7576106035944268	[524]	[152,96,NaN]	-6	hSpCas9	negative selection	9813154
13365406	13365429	19	+	27869803	PATU8988S	viability after 35 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.037447961345796976	[869]	[303,378,NaN]	0	hSpCas9	negative selection	9813155
13371757	13371780	19	-	27869803	PATU8988S	viability after 35 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-0.7583533628622166	[385]	[49,133,NaN]	-6	hSpCas9	negative selection	9813156
13452932	13452955	19	+	27869803	PATU8988S	viability after 35 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.02658663999560429	[239]	[79,116,NaN]	0	hSpCas9	negative selection	9813157
13455154	13455177	19	-	27869803	PATU8988S	viability after 35 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.38443380573270614	[199]	[168,40,NaN]	4	hSpCas9	negative selection	9813159
13505966	13505989	19	+	27869803	PATU8988S	viability after 35 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.36885750972002507	[1253]	[732,570,NaN]	4	hSpCas9	negative selection	9813163
13359751	13359774	19	+	27869803	PATU8988S	viability after 31 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.47125835239826636	[524]	[172,122,NaN]	-5	hSpCas9	negative selection	9895603
13365406	13365429	19	+	27869803	PATU8988S	viability after 31 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.09213692284903219	[869]	[346,297,NaN]	-1	hSpCas9	negative selection	9895604
13371757	13371780	19	-	27869803	PATU8988S	viability after 31 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-1.3785308891139114	[385]	[45,75,NaN]	-8	hSpCas9	negative selection	9895605
13452932	13452955	19	+	27869803	PATU8988S	viability after 31 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	0.16589667540189512	[239]	[109,103,NaN]	2	hSpCas9	negative selection	9895606
13455154	13455177	19	-	27869803	PATU8988S	viability after 31 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.388168947680017	[199]	[150,44,NaN]	5	hSpCas9	negative selection	9895608
13505966	13505989	19	+	27869803	PATU8988S	viability after 31 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	0.4474760554391719	[1253]	[581,808,NaN]	5	hSpCas9	negative selection	9895612
13359751	13359774	19	+	27869803	HPAFII	viability after 35 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	0.26481047585907025	[209]	[59,203,NaN]	1	hSpCas9	negative selection	9978052
13365406	13365429	19	+	27869803	HPAFII	viability after 35 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.3058230223207543	[344]	[137,144,NaN]	-2	hSpCas9	negative selection	9978053
13371757	13371780	19	-	27869803	HPAFII	viability after 35 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-2.0853948632365906	[177]	[16,25,NaN]	-8	hSpCas9	negative selection	9978054
13452932	13452955	19	+	27869803	HPAFII	viability after 35 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.12769208038879232	[172]	[50,112,NaN]	-1	hSpCas9	negative selection	9978055
13455154	13455177	19	-	27869803	HPAFII	viability after 35 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.6238794259711664	[82]	[36,95,NaN]	4	hSpCas9	negative selection	9978057
13505966	13505989	19	+	27869803	HPAFII	viability after 35 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	1.726769711224883	[456]	[856,662,NaN]	9	hSpCas9	negative selection	9978061
13359751	13359774	19	+	27869803	HPAFII	viability after 31 days	GCGGGCTCTTCTGTCCCACATGG	CACNA1A	ENSG00000141837	-0.86518051088572	[209]	[57,71,NaN]	-5	hSpCas9	negative selection	10060501
13365406	13365429	19	+	27869803	HPAFII	viability after 31 days	AGGAGGCCGATCTGCAGCAAAGG	CACNA1A	ENSG00000141837	-0.7337800249294377	[344]	[125,105,NaN]	-5	hSpCas9	negative selection	10060502
13371757	13371780	19	-	27869803	HPAFII	viability after 31 days	CATCTTGGCGACAGTTGGGACGG	CACNA1A	ENSG00000141837	-1.1838677319078963	[177]	[20,68,NaN]	-6	hSpCas9	negative selection	10060503
13452932	13452955	19	+	27869803	HPAFII	viability after 31 days	TTTGTGGAAGGCAAACCCAAGGG	CACNA1A	ENSG00000141837	-0.3158548090992185	[172]	[77,77,NaN]	-2	hSpCas9	negative selection	10060504
13455154	13455177	19	-	27869803	HPAFII	viability after 31 days	GAATTGCATCGTCCTCGCACTGG	CACNA1A	ENSG00000141837	0.17453880232774188	[82]	[42,62,NaN]	1	hSpCas9	negative selection	10060506
13505966	13505989	19	+	27869803	HPAFII	viability after 31 days	CCACGTTGTCTTCGCTGAAGAGG	CACNA1A	ENSG00000141837	1.7314739862069404	[456]	[888,810,NaN]	9	hSpCas9	negative selection	10060510
13298713	13298736	19	-	28162770	P31FUJ	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-1.8635683947486599	[95]	[30]	-8	hSpCas9	negative selection	10124827
13298914	13298937	19	-	28162770	P31FUJ	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	0.9263963904348753	[89]	[200]	9	hSpCas9	negative selection	10124828
13298558	13298581	19	-	28162770	P31FUJ	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-4.83766426257324	[72]	[2]	-9	hSpCas9	negative selection	10124829
13285131	13285154	19	-	28162770	P31FUJ	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	0.4094351016585267	[106]	[166]	4	hSpCas9	negative selection	10124830
13262763	13262786	19	+	28162770	P31FUJ	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.32205826451735853	[225]	[331]	3	hSpCas9	negative selection	10124831
13231833	13231856	19	+	28162770	P31FUJ	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.05084723126316826	[358]	[436]	0	hSpCas9	negative selection	10124832
13506012	13506035	19	+	28162770	P31FUJ	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.692233823051676	[21]	[15]	-5	hSpCas9	negative selection	10124833
13452886	13452909	19	-	28162770	P31FUJ	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	1.0726108036899669	[368]	[911]	9	hSpCas9	negative selection	10124834
13334454	13334477	19	-	28162770	P31FUJ	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	0.5015379203450041	[219]	[365]	5	hSpCas9	negative selection	10124835
13317208	13317231	19	+	28162770	P31FUJ	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-4.625119627193138	[20]	[0]	-9	hSpCas9	negative selection	10124836
13298713	13298736	19	-	28162770	TF1	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10294193
13298914	13298937	19	-	28162770	TF1	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10294194
13298558	13298581	19	-	28162770	TF1	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10294195
13285131	13285154	19	-	28162770	TF1	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[126]	1	hSpCas9	negative selection	10294196
13262763	13262786	19	+	28162770	TF1	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[202]	1	hSpCas9	negative selection	10294197
13231833	13231856	19	+	28162770	TF1	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[188]	1	hSpCas9	negative selection	10294198
13506012	13506035	19	+	28162770	TF1	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10294199
13452886	13452909	19	-	28162770	TF1	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[308]	1	hSpCas9	negative selection	10294200
13334454	13334477	19	-	28162770	TF1	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10294201
13317208	13317231	19	+	28162770	TF1	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	NaN	[NaN]	[6]	1	hSpCas9	negative selection	10294202
13298713	13298736	19	-	28162770	SKM1	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-0.9649596518640484	[52]	[47]	-6	hSpCas9	negative selection	10463559
13298914	13298937	19	-	28162770	SKM1	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-1.3365748708517637	[29]	[20]	-7	hSpCas9	negative selection	10463560
13298558	13298581	19	-	28162770	SKM1	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-4.0950201924284215	[28]	[2]	-9	hSpCas9	negative selection	10463561
13285131	13285154	19	-	28162770	SKM1	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-0.001551118352718206	[46]	[82]	0	hSpCas9	negative selection	10463562
13262763	13262786	19	+	28162770	SKM1	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.05442361685946201	[66]	[122]	0	hSpCas9	negative selection	10463563
13231833	13231856	19	+	28162770	SKM1	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	-0.2425773808422793	[86]	[129]	-2	hSpCas9	negative selection	10463564
13506012	13506035	19	+	28162770	SKM1	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.5000736031346436	[3]	[4]	-4	hSpCas9	negative selection	10463565
13452886	13452909	19	-	28162770	SKM1	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	-0.35093016382883385	[100]	[139]	-3	hSpCas9	negative selection	10463566
13334454	13334477	19	-	28162770	SKM1	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	-0.2005133212757353	[38]	[59]	-2	hSpCas9	negative selection	10463567
13317208	13317231	19	+	28162770	SKM1	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-0.5000736031346436	[3]	[4]	-4	hSpCas9	negative selection	10463568
13298713	13298736	19	-	28162770	SKM1	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-0.9649596518640484	[52]	[47]	-6	hSpCas9	negative selection	10632925
13298914	13298937	19	-	28162770	SKM1	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-1.3365748708517637	[29]	[20]	-7	hSpCas9	negative selection	10632926
13298558	13298581	19	-	28162770	SKM1	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-4.0950201924284215	[28]	[2]	-9	hSpCas9	negative selection	10632927
13285131	13285154	19	-	28162770	SKM1	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-0.001551118352718206	[46]	[82]	0	hSpCas9	negative selection	10632928
13262763	13262786	19	+	28162770	SKM1	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.05442361685946201	[66]	[122]	0	hSpCas9	negative selection	10632929
13231833	13231856	19	+	28162770	SKM1	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	-0.2425773808422793	[86]	[129]	-2	hSpCas9	negative selection	10632930
13506012	13506035	19	+	28162770	SKM1	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.5000736031346436	[3]	[4]	-4	hSpCas9	negative selection	10632931
13452886	13452909	19	-	28162770	SKM1	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	-0.35093016382883385	[100]	[139]	-3	hSpCas9	negative selection	10632932
13334454	13334477	19	-	28162770	SKM1	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	-0.2005133212757353	[38]	[59]	-2	hSpCas9	negative selection	10632933
13317208	13317231	19	+	28162770	SKM1	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-0.5000736031346436	[3]	[4]	-4	hSpCas9	negative selection	10632934
13298713	13298736	19	-	28162770	PL21	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	0.308515775534112	[140]	[75]	2	hSpCas9	negative selection	10802291
13298914	13298937	19	-	28162770	PL21	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	0.8028041169439353	[53]	[40]	7	hSpCas9	negative selection	10802292
13298558	13298581	19	-	28162770	PL21	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-3.7067509811191988	[29]	[0]	-9	hSpCas9	negative selection	10802293
13285131	13285154	19	-	28162770	PL21	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-1.4481488216006653	[162]	[25]	-7	hSpCas9	negative selection	10802294
13262763	13262786	19	+	28162770	PL21	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.7237015705463332	[223]	[160]	6	hSpCas9	negative selection	10802295
13231833	13231856	19	+	28162770	PL21	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.4799986429644728	[340]	[206]	4	hSpCas9	negative selection	10802296
13506012	13506035	19	+	28162770	PL21	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.38482288623183614	[2]	[0]	-3	hSpCas9	negative selection	10802297
13452886	13452909	19	-	28162770	PL21	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	0.4285224736681509	[308]	[180]	4	hSpCas9	negative selection	10802298
13334454	13334477	19	-	28162770	PL21	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	-1.1391705586262786	[166]	[32]	-6	hSpCas9	negative selection	10802299
13317208	13317231	19	+	28162770	PL21	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-1.5003001036517727	[25]	[3]	-7	hSpCas9	negative selection	10802300
13298713	13298736	19	-	28162770	P31FUJ	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-1.8635683947486599	[95]	[30]	-8	hSpCas9	negative selection	10971657
13298914	13298937	19	-	28162770	P31FUJ	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	0.9263963904348753	[89]	[200]	9	hSpCas9	negative selection	10971658
13298558	13298581	19	-	28162770	P31FUJ	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-4.83766426257324	[72]	[2]	-9	hSpCas9	negative selection	10971659
13285131	13285154	19	-	28162770	P31FUJ	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	0.4094351016585267	[106]	[166]	4	hSpCas9	negative selection	10971660
13262763	13262786	19	+	28162770	P31FUJ	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.32205826451735853	[225]	[331]	3	hSpCas9	negative selection	10971661
13231833	13231856	19	+	28162770	P31FUJ	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.05084723126316826	[358]	[436]	0	hSpCas9	negative selection	10971662
13506012	13506035	19	+	28162770	P31FUJ	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.692233823051676	[21]	[15]	-5	hSpCas9	negative selection	10971663
13452886	13452909	19	-	28162770	P31FUJ	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	1.0726108036899669	[368]	[911]	9	hSpCas9	negative selection	10971664
13334454	13334477	19	-	28162770	P31FUJ	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	0.5015379203450041	[219]	[365]	5	hSpCas9	negative selection	10971665
13317208	13317231	19	+	28162770	P31FUJ	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-4.625119627193138	[20]	[0]	-9	hSpCas9	negative selection	10971666
13298713	13298736	19	-	28162770	OCIAML5	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-1.9374580620946416	[86]	[40]	-8	hSpCas9	negative selection	11141023
13298914	13298937	19	-	28162770	OCIAML5	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-1.589032165030203	[44]	[26]	-7	hSpCas9	negative selection	11141024
13298558	13298581	19	-	28162770	OCIAML5	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	0.017872888571630163	[28]	[52]	0	hSpCas9	negative selection	11141025
13285131	13285154	19	-	28162770	OCIAML5	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-0.42792686447790074	[78]	[105]	-3	hSpCas9	negative selection	11141026
13262763	13262786	19	+	28162770	OCIAML5	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.10518378167666595	[136]	[265]	0	hSpCas9	negative selection	11141027
13231833	13231856	19	+	28162770	OCIAML5	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	-0.4570037713464192	[199]	[262]	-3	hSpCas9	negative selection	11141028
13506012	13506035	19	+	28162770	OCIAML5	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-4.659421492921601	[27]	[1]	-9	hSpCas9	negative selection	11141029
13452886	13452909	19	-	28162770	OCIAML5	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	0.46338718986281546	[267]	[666]	4	hSpCas9	negative selection	11141030
13334454	13334477	19	-	28162770	OCIAML5	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	-0.24147826246734644	[92]	[141]	-2	hSpCas9	negative selection	11141031
13317208	13317231	19	+	28162770	OCIAML5	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	0.9134681754989802	[9]	[33]	7	hSpCas9	negative selection	11141032
13298713	13298736	19	-	28162770	EOL1	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-0.7285862317922008	[194]	[61]	-5	hSpCas9	negative selection	11310389
13298914	13298937	19	-	28162770	EOL1	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-0.9685370245129534	[103]	[27]	-6	hSpCas9	negative selection	11310390
13298558	13298581	19	-	28162770	EOL1	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-2.4677696512082257	[104]	[9]	-8	hSpCas9	negative selection	11310391
13285131	13285154	19	-	28162770	EOL1	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-0.8277930484825875	[282]	[83]	-5	hSpCas9	negative selection	11310392
13262763	13262786	19	+	28162770	EOL1	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.024083445121448832	[391]	[209]	0	hSpCas9	negative selection	11310393
13231833	13231856	19	+	28162770	EOL1	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	-1.0476042434763488	[666]	[169]	-6	hSpCas9	negative selection	11310394
13506012	13506035	19	+	28162770	EOL1	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-3.5348838470667627	[21]	[0]	-9	hSpCas9	negative selection	11310395
13452886	13452909	19	-	28162770	EOL1	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	0.15538526116323936	[437]	[256]	1	hSpCas9	negative selection	11310396
13334454	13334477	19	-	28162770	EOL1	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	1.6060182531450373	[158]	[254]	9	hSpCas9	negative selection	11310397
13317208	13317231	19	+	28162770	EOL1	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	0.754622770128222	[26]	[23]	6	hSpCas9	negative selection	11310398
13298713	13298736	19	-	28162770	MOLM13	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-2.204535960426917	[152]	[23]	-7	hSpCas9	negative selection	11479755
13298914	13298937	19	-	28162770	MOLM13	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-0.054063321650776874	[111]	[77]	0	hSpCas9	negative selection	11479756
13298558	13298581	19	-	28162770	MOLM13	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-1.599224814313958	[87]	[20]	-7	hSpCas9	negative selection	11479757
13285131	13285154	19	-	28162770	MOLM13	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-0.056531577241526465	[209]	[145]	0	hSpCas9	negative selection	11479758
13262763	13262786	19	+	28162770	MOLM13	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.18324851952140983	[295]	[242]	1	hSpCas9	negative selection	11479759
13231833	13231856	19	+	28162770	MOLM13	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.6558790987488827	[387]	[441]	5	hSpCas9	negative selection	11479760
13506012	13506035	19	+	28162770	MOLM13	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	2.0779428632285653	[18]	[57]	9	hSpCas9	negative selection	11479761
13452886	13452909	19	-	28162770	MOLM13	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	-0.12407650691433991	[412]	[273]	-1	hSpCas9	negative selection	11479762
13334454	13334477	19	-	28162770	MOLM13	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	-0.2751379654088286	[158]	[94]	-2	hSpCas9	negative selection	11479763
13317208	13317231	19	+	28162770	MOLM13	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-2.339465540513026	[13]	[1]	-8	hSpCas9	negative selection	11479764
13298713	13298736	19	-	28162770	HEL	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-0.5213805477607496	[185]	[82]	-4	hSpCas9	negative selection	11649121
13298914	13298937	19	-	28162770	HEL	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	0.9359352083444031	[70]	[86]	7	hSpCas9	negative selection	11649122
13298558	13298581	19	-	28162770	HEL	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-5.401655287358096	[65]	[0]	-9	hSpCas9	negative selection	11649123
13285131	13285154	19	-	28162770	HEL	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	0.1937540007981755	[171]	[125]	1	hSpCas9	negative selection	11649124
13262763	13262786	19	+	28162770	HEL	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.5723495041089589	[251]	[239]	5	hSpCas9	negative selection	11649125
13231833	13231856	19	+	28162770	HEL	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.10547307331049705	[356]	[245]	0	hSpCas9	negative selection	11649126
13506012	13506035	19	+	28162770	HEL	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	1.029761955109604	[12]	[16]	8	hSpCas9	negative selection	11649127
13452886	13452909	19	-	28162770	HEL	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	-0.21335175660092953	[428]	[236]	-1	hSpCas9	negative selection	11649128
13334454	13334477	19	-	28162770	HEL	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	0.8420476402237635	[134]	[154]	7	hSpCas9	negative selection	11649129
13317208	13317231	19	+	28162770	HEL	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	0.5902714121062216	[27]	[26]	5	hSpCas9	negative selection	11649130
13298713	13298736	19	-	28162770	MV411	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-1.2944562280464946	[98]	[33]	-7	hSpCas9	negative selection	11818487
13298914	13298937	19	-	28162770	MV411	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-1.1778682839498957	[93]	[34]	-6	hSpCas9	negative selection	11818488
13298558	13298581	19	-	28162770	MV411	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-3.922487450659537	[17]	[0]	-9	hSpCas9	negative selection	11818489
13285131	13285154	19	-	28162770	MV411	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-0.8330523670775926	[128]	[60]	-5	hSpCas9	negative selection	11818490
13262763	13262786	19	+	28162770	MV411	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.33587551545035926	[173]	[184]	3	hSpCas9	negative selection	11818491
13231833	13231856	19	+	28162770	MV411	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	-0.3398688904066801	[307]	[204]	-3	hSpCas9	negative selection	11818492
13506012	13506035	19	+	28162770	MV411	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.7525624492172245	[7]	[3]	-5	hSpCas9	negative selection	11818493
13452886	13452909	19	-	28162770	MV411	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	0.5340587769341851	[272]	[332]	5	hSpCas9	negative selection	11818494
13334454	13334477	19	-	28162770	MV411	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	2.415332016997717	[78]	[354]	9	hSpCas9	negative selection	11818495
13317208	13317231	19	+	28162770	MV411	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-4.39641863899195	[24]	[0]	-9	hSpCas9	negative selection	11818496
13298713	13298736	19	-	28162770	MONOMAC1	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-1.384663850235325	[81]	[35]	-8	hSpCas9	negative selection	11987853
13298914	13298937	19	-	28162770	MONOMAC1	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	0.734250402856432	[42]	[81]	7	hSpCas9	negative selection	11987854
13298558	13298581	19	-	28162770	MONOMAC1	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-5.366961848501866	[35]	[0]	-9	hSpCas9	negative selection	11987855
13285131	13285154	19	-	28162770	MONOMAC1	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-0.05183893151961816	[84]	[93]	0	hSpCas9	negative selection	11987856
13262763	13262786	19	+	28162770	MONOMAC1	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.4559024474776092	[151]	[238]	4	hSpCas9	negative selection	11987857
13231833	13231856	19	+	28162770	MONOMAC1	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.1615599578752055	[201]	[258]	1	hSpCas9	negative selection	11987858
13506012	13506035	19	+	28162770	MONOMAC1	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.7819993477807099	[5]	[3]	-6	hSpCas9	negative selection	11987859
13452886	13452909	19	-	28162770	MONOMAC1	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	1.0785975955538736	[227]	[551]	8	hSpCas9	negative selection	11987860
13334454	13334477	19	-	28162770	MONOMAC1	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	1.0577770519692715	[87]	[209]	8	hSpCas9	negative selection	11987861
13317208	13317231	19	+	28162770	MONOMAC1	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	1.5191701869398555	[6]	[22]	9	hSpCas9	negative selection	11987862
13298713	13298736	19	-	28162770	OCIAML2	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-2.705095078879184	[19]	[16]	-9	hSpCas9	negative selection	12157219
13298914	13298937	19	-	28162770	OCIAML2	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-0.7544227912427526	[13]	[45]	-5	hSpCas9	negative selection	12157220
13298558	13298581	19	-	28162770	OCIAML2	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-5.377520420850679	[14]	[1]	-9	hSpCas9	negative selection	12157221
13285131	13285154	19	-	28162770	OCIAML2	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	0.028602801453110893	[25]	[146]	0	hSpCas9	negative selection	12157222
13262763	13262786	19	+	28162770	OCIAML2	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	-0.04793875341988196	[46]	[251]	0	hSpCas9	negative selection	12157223
13231833	13231856	19	+	28162770	OCIAML2	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.24881800766601536	[57]	[381]	2	hSpCas9	negative selection	12157224
13506012	13506035	19	+	28162770	OCIAML2	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.6632749031845577	[1]	[6]	-5	hSpCas9	negative selection	12157225
13452886	13452909	19	-	28162770	OCIAML2	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	-0.27876227091917183	[57]	[264]	-2	hSpCas9	negative selection	12157226
13334454	13334477	19	-	28162770	OCIAML2	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	-0.5902114409948336	[21]	[80]	-4	hSpCas9	negative selection	12157227
13317208	13317231	19	+	28162770	OCIAML2	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-0.47062982524216146	[1]	[7]	-4	hSpCas9	negative selection	12157228
13298713	13298736	19	-	28162770	OCIAML3	viability	GGAGGGTCCGGAGGACAAGGCGG	CACNA1A	ENSG00000141837	-0.9684031551056609	[34]	[53]	-6	hSpCas9	negative selection	12326585
13298914	13298937	19	-	28162770	OCIAML3	viability	CGAGTCGGACCACCACGCCCGGG	CACNA1A	ENSG00000141837	-0.5940076403241634	[22]	[45]	-4	hSpCas9	negative selection	12326586
13298558	13298581	19	-	28162770	OCIAML3	viability	GGAGGGAGGACAAGGAGCGGAGG	CACNA1A	ENSG00000141837	-4.053439258961461	[10]	[1]	-9	hSpCas9	negative selection	12326587
13285131	13285154	19	-	28162770	OCIAML3	viability	GAGGAGGAGGAAGACGACCGTGG	CACNA1A	ENSG00000141837	-1.0503859349839066	[58]	[85]	-6	hSpCas9	negative selection	12326588
13262763	13262786	19	+	28162770	OCIAML3	viability	TAAGAGGTCGTAGCACCCGGAGG	CACNA1A	ENSG00000141837	0.028187766595968167	[50]	[156]	0	hSpCas9	negative selection	12326589
13231833	13231856	19	+	28162770	OCIAML3	viability	GTTGTGCCAAGCTTCCCCGGTGG	CACNA1A	ENSG00000141837	0.10331722585295067	[106]	[346]	1	hSpCas9	negative selection	12326590
13506012	13506035	19	+	28162770	OCIAML3	viability	GCAGTTCTGTCGGACGGGGATGG	CACNA1A	ENSG00000141837	-0.17897014104531994	[2]	[7]	-1	hSpCas9	negative selection	12326591
13452886	13452909	19	-	28162770	OCIAML3	viability	GAATGTCATGGACTTTGTGGTGG	CACNA1A	ENSG00000141837	0.4015327114851367	[80]	[322]	4	hSpCas9	negative selection	12326592
13334454	13334477	19	-	28162770	OCIAML3	viability	GGGAACGGGTGGAGAACCGGCGG	CACNA1A	ENSG00000141837	0.33760538469558676	[26]	[102]	3	hSpCas9	negative selection	12326593
13317208	13317231	19	+	28162770	OCIAML3	viability	CCTGAGTTTTGACCATGCGGCGG	CACNA1A	ENSG00000141837	-1.594007640324163	[1]	[1]	-8	hSpCas9	negative selection	12326594