Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:777
• Symbol:CACNA1E
• Description:calcium voltage-gated channel subunit alpha1 E

DataSource: http://genomecrispr.dkfz.de/#!/results/CACNA1E

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
181577817	181577840	1	-	26472758	Jiyoye	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-0.6986192825167233	[197]	[91]	-5	hSpCas9	negative selection	22416
181785391	181785414	1	+	26472758	Jiyoye	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-1.8266218031028236	[126]	[26]	-8	hSpCas9	negative selection	22417
181651357	181651380	1	-	26472758	Jiyoye	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.6128504078973875	[123]	[142]	4	hSpCas9	negative selection	22418
181710989	181711012	1	+	26472758	Jiyoye	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.07112617837385815	[153]	[121]	0	hSpCas9	negative selection	22419
181718123	181718146	1	-	26472758	Jiyoye	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.7080418608654062	[68]	[84]	5	hSpCas9	negative selection	22420
181732468	181732491	1	+	26472758	Jiyoye	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.679124464888347	[154]	[72]	-5	hSpCas9	negative selection	22421
181732622	181732645	1	+	26472758	Jiyoye	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-0.9605564029946136	[79]	[30]	-6	hSpCas9	negative selection	22422
181736372	181736395	1	+	26472758	Jiyoye	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	1.0592520780855665	[34]	[54]	7	hSpCas9	negative selection	22423
181739200	181739223	1	+	26472758	Jiyoye	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	-0.31271669930139123	[335]	[203]	-2	hSpCas9	negative selection	22424
181756944	181756967	1	+	26472758	Jiyoye	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-0.49971521410264497	[104]	[55]	-4	hSpCas9	negative selection	22425
181733555	181733578	1	+	26472758	Jiyoye	viability	GAGCAGGAGCCAGAAGGCAGCAG	CACNA1E	ENSG00000198216	-2.070871915298771	[155]	[27]	-8	hSpCas9	negative selection	130748
181577817	181577840	1	-	26472758	KBM7	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	0.4333809000664592	[561,466]	[368,285]	4	hSpCas9	negative selection	213534
181785391	181785414	1	+	26472758	KBM7	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-0.9998328619718972	[405,396]	[89,98]	-6	hSpCas9	negative selection	213535
181651357	181651380	1	-	26472758	KBM7	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.2227674355526027	[1008,700]	[380,302]	-2	hSpCas9	negative selection	213536
181710989	181711012	1	+	26472758	KBM7	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.2652548614203349	[623,515]	[262,371]	2	hSpCas9	negative selection	213537
181718123	181718146	1	-	26472758	KBM7	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.06977066706593144	[451,430]	[257,182]	0	hSpCas9	negative selection	213538
181732468	181732491	1	+	26472758	KBM7	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.5995200230864798	[935,799]	[343,200]	-5	hSpCas9	negative selection	213539
181732622	181732645	1	+	26472758	KBM7	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	0.381863719716664	[268,265]	[143,182]	4	hSpCas9	negative selection	213540
181736372	181736395	1	+	26472758	KBM7	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.5820075777789689	[275,498]	[185,367]	6	hSpCas9	negative selection	213541
181739200	181739223	1	+	26472758	KBM7	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.31770326385684666	[1413,1101]	[741,721]	3	hSpCas9	negative selection	213542
181756944	181756967	1	+	26472758	KBM7	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-0.8060846322010047	[665,481]	[169,136]	-6	hSpCas9	negative selection	213543
181733555	181733578	1	+	26472758	KBM7	viability	GAGCAGGAGCCAGAAGGCAGCAG	CACNA1E	ENSG00000198216	-2.289831696874331	[390,284]	[38,25]	-8	hSpCas9	negative selection	321866
181577817	181577840	1	-	26472758	Raji	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	0.5224210346524432	[287]	[95]	5	hSpCas9	negative selection	404652
181785391	181785414	1	+	26472758	Raji	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-1.0545041470032945	[178]	[19]	-6	hSpCas9	negative selection	404653
181651357	181651380	1	-	26472758	Raji	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.0749620576812221	[404]	[98]	0	hSpCas9	negative selection	404654
181710989	181711012	1	+	26472758	Raji	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.703750799367005	[335]	[126]	6	hSpCas9	negative selection	404655
181718123	181718146	1	-	26472758	Raji	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.1986793693931499	[198]	[52]	1	hSpCas9	negative selection	404656
181732468	181732491	1	+	26472758	Raji	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-1.3229670193997485	[441]	[40]	-7	hSpCas9	negative selection	404657
181732622	181732645	1	+	26472758	Raji	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-0.35204808326369774	[142]	[25]	-3	hSpCas9	negative selection	404658
181736372	181736395	1	+	26472758	Raji	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.36714280917453246	[146]	[43]	3	hSpCas9	negative selection	404659
181739200	181739223	1	+	26472758	Raji	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.07891688007153919	[562]	[137]	0	hSpCas9	negative selection	404660
181756944	181756967	1	+	26472758	Raji	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-1.1984248941504858	[266]	[26]	-7	hSpCas9	negative selection	404661
181733555	181733578	1	+	26472758	Raji	viability	GAGCAGGAGCCAGAAGGCAGCAG	CACNA1E	ENSG00000198216	-1.4666078475265534	[130]	[10]	-7	hSpCas9	negative selection	512984
181577817	181577840	1	-	26472758	K562	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-0.19885245234134097	[343]	[252]	-1	hSpCas9	negative selection	595770
181785391	181785414	1	+	26472758	K562	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-3.501008445247956	[227]	[16]	-8	hSpCas9	negative selection	595771
181651357	181651380	1	-	26472758	K562	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.03859117923912925	[533]	[462]	0	hSpCas9	negative selection	595772
181710989	181711012	1	+	26472758	K562	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	-0.28443867116955895	[579]	[401]	-2	hSpCas9	negative selection	595773
181718123	181718146	1	-	26472758	K562	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.9491961955424647	[280]	[457]	7	hSpCas9	negative selection	595774
181732468	181732491	1	+	26472758	K562	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-2.276818175444322	[619]	[107]	-7	hSpCas9	negative selection	595775
181732622	181732645	1	+	26472758	K562	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-1.2580816128627363	[254]	[89]	-6	hSpCas9	negative selection	595776
181736372	181736395	1	+	26472758	K562	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.3905755631758093	[271]	[300]	3	hSpCas9	negative selection	595777
181739200	181739223	1	+	26472758	K562	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	-0.08363547001775706	[1061]	[845]	0	hSpCas9	negative selection	595778
181756944	181756967	1	+	26472758	K562	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-2.7424058835858194	[435]	[54]	-8	hSpCas9	negative selection	595779
181733555	181733578	1	+	26472758	K562	viability	GAGCAGGAGCCAGAAGGCAGCAG	CACNA1E	ENSG00000198216	-3.3776330917899293	[393]	[31]	-8	hSpCas9	negative selection	704102
181483791	181483814	1	+	26627737	DLD1	viability	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	1.5873866807881338	[124]	[70,180,104]	9	hSpCas9	negative selection	767882
181510566	181510589	1	-	26627737	DLD1	viability	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.418207785502434	[1205]	[490,831,242]	4	hSpCas9	negative selection	767883
181511463	181511486	1	-	26627737	DLD1	viability	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.4960989755998939	[1469]	[331,370,282]	-5	hSpCas9	negative selection	767884
181577835	181577858	1	-	26627737	DLD1	viability	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-0.5740076230312772	[436]	[50,80,135]	-5	hSpCas9	negative selection	767891
181580649	181580672	1	+	26627737	DLD1	viability	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.4239483317486077	[728]	[250,416,260]	4	hSpCas9	negative selection	767892
181651357	181651380	1	-	26627737	DLD1	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.16845053511164565	[220]	[98,29,54]	-2	hSpCas9	negative selection	767893
181483791	181483814	1	+	26627737	GBM cells	viability after 5 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	0.45271544412038117	[155]	[139,88]	6	hSpCas9	negative selection	850197
181510566	181510589	1	-	26627737	GBM cells	viability after 5 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.08566260715318097	[520]	[318,273]	1	hSpCas9	negative selection	850198
181511463	181511486	1	-	26627737	GBM cells	viability after 5 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.634386506012978	[575]	[172,224]	-7	hSpCas9	negative selection	850199
181577835	181577858	1	-	26627737	GBM cells	viability after 5 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	1.000793488904899	[81]	[117,57]	9	hSpCas9	negative selection	850206
181580649	181580672	1	+	26627737	GBM cells	viability after 5 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.00033350080301808305	[552]	[299,292]	0	hSpCas9	negative selection	850207
181651357	181651380	1	-	26627737	GBM cells	viability after 5 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.13314733434661297	[181]	[115,61]	-2	hSpCas9	negative selection	850208
181483791	181483814	1	+	26627737	GBM cells	viability after 13 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	0.08501364334062533	[155]	[134,52]	1	hSpCas9	negative selection	932512
181510566	181510589	1	-	26627737	GBM cells	viability after 13 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.4438309382093384	[520]	[437,340]	5	hSpCas9	negative selection	932513
181511463	181511486	1	-	26627737	GBM cells	viability after 13 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.8795545846688625	[575]	[181,159]	-7	hSpCas9	negative selection	932514
181577835	181577858	1	-	26627737	GBM cells	viability after 13 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	0.20960905402478014	[81]	[51,50]	2	hSpCas9	negative selection	932521
181580649	181580672	1	+	26627737	GBM cells	viability after 13 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.22175418069267683	[552]	[350,348]	3	hSpCas9	negative selection	932522
181651357	181651380	1	-	26627737	GBM cells	viability after 13 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.2817293841002466	[181]	[140,102]	3	hSpCas9	negative selection	932523
181483791	181483814	1	+	26627737	GBM cells	viability after 21 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-1.4613517546397141	[155]	[35,25]	-8	hSpCas9	negative selection	1014827
181510566	181510589	1	-	26627737	GBM cells	viability after 21 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.13926235626028838	[520]	[317,305]	1	hSpCas9	negative selection	1014828
181511463	181511486	1	-	26627737	GBM cells	viability after 21 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-1.0283280489773736	[575]	[166,140]	-7	hSpCas9	negative selection	1014829
181577835	181577858	1	-	26627737	GBM cells	viability after 21 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	1.412641494656216	[81]	[127,109]	9	hSpCas9	negative selection	1014836
181580649	181580672	1	+	26627737	GBM cells	viability after 21 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.1059760657342852	[552]	[338,308]	1	hSpCas9	negative selection	1014837
181651357	181651380	1	-	26627737	GBM cells	viability after 21 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.0004993485395566877	[181]	[100,96]	0	hSpCas9	negative selection	1014838
181483791	181483814	1	+	26627737	RPE1	viability after 9 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	1.0852843255698672	[275]	[164,206]	6	hSpCas9	negative selection	1097142
181510566	181510589	1	-	26627737	RPE1	viability after 9 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	1.3962481593549354	[1339]	[998,1239]	7	hSpCas9	negative selection	1097143
181511463	181511486	1	-	26627737	RPE1	viability after 9 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.7312765420571452	[2405]	[320,624]	-5	hSpCas9	negative selection	1097144
181577835	181577858	1	-	26627737	RPE1	viability after 9 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-0.23038977598462632	[813]	[204,232]	-2	hSpCas9	negative selection	1097151
181580649	181580672	1	+	26627737	RPE1	viability after 9 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	1.7806012188434222	[800]	[737,1020]	8	hSpCas9	negative selection	1097152
181651357	181651380	1	-	26627737	RPE1	viability after 9 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.9872013424931453	[661]	[128,72]	-6	hSpCas9	negative selection	1097153
181483791	181483814	1	+	26627737	RPE1	viability after 12 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	1.512782772121632	[275]	[214,207]	8	hSpCas9	negative selection	1179457
181510566	181510589	1	-	26627737	RPE1	viability after 12 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	1.2375692093184574	[1339]	[828,869]	7	hSpCas9	negative selection	1179458
181511463	181511486	1	-	26627737	RPE1	viability after 12 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.7459898046122752	[2405]	[297,477]	-5	hSpCas9	negative selection	1179459
181577835	181577858	1	-	26627737	RPE1	viability after 12 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-0.7695568599095663	[813]	[86,171]	-5	hSpCas9	negative selection	1179466
181580649	181580672	1	+	26627737	RPE1	viability after 12 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	1.5839278279798246	[800]	[666,621]	8	hSpCas9	negative selection	1179467
181651357	181651380	1	-	26627737	RPE1	viability after 12 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.9265798207668715	[661]	[129,54]	-6	hSpCas9	negative selection	1179468
181483791	181483814	1	+	26627737	RPE1	viability after 15 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	1.5692907536245615	[275]	[248,214]	8	hSpCas9	negative selection	1261772
181510566	181510589	1	-	26627737	RPE1	viability after 15 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	1.065620542651663	[1339]	[686,895]	6	hSpCas9	negative selection	1261773
181511463	181511486	1	-	26627737	RPE1	viability after 15 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.5756076679051032	[2405]	[417,493]	-4	hSpCas9	negative selection	1261774
181577835	181577858	1	-	26627737	RPE1	viability after 15 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-1.1669874406116092	[813]	[127,77]	-6	hSpCas9	negative selection	1261781
181580649	181580672	1	+	26627737	RPE1	viability after 15 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	1.440188023144345	[800]	[594,633]	7	hSpCas9	negative selection	1261782
181651357	181651380	1	-	26627737	RPE1	viability after 15 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-1.1607069102278127	[661]	[68,97]	-6	hSpCas9	negative selection	1261783
181483791	181483814	1	+	26627737	RPE1	viability after 18 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	0.5061586567586147	[275]	[84,127]	3	hSpCas9	negative selection	1344087
181510566	181510589	1	-	26627737	RPE1	viability after 18 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	1.2952966561394246	[1339]	[829,948]	7	hSpCas9	negative selection	1344088
181511463	181511486	1	-	26627737	RPE1	viability after 18 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.9021491502026348	[2405]	[330,364]	-5	hSpCas9	negative selection	1344089
181577835	181577858	1	-	26627737	RPE1	viability after 18 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-1.1838222356895913	[813]	[116,74]	-6	hSpCas9	negative selection	1344096
181580649	181580672	1	+	26627737	RPE1	viability after 18 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	1.6735306042906928	[800]	[661,718]	8	hSpCas9	negative selection	1344097
181651357	181651380	1	-	26627737	RPE1	viability after 18 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.8251790137938154	[661]	[95,105]	-5	hSpCas9	negative selection	1344098
181483791	181483814	1	+	26627737	HeLa	viability after 8 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	1.2297918131723862	[162]	[169,150,177]	8	hSpCas9	negative selection	1426402
181510566	181510589	1	-	26627737	HeLa	viability after 8 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.6575581242202375	[637]	[611,493,258]	5	hSpCas9	negative selection	1426403
181511463	181511486	1	-	26627737	HeLa	viability after 8 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.0513110916576629	[620]	[386,219,206]	0	hSpCas9	negative selection	1426404
181577835	181577858	1	-	26627737	HeLa	viability after 8 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	2.5016228666912843	[56]	[116,273,32]	9	hSpCas9	negative selection	1426411
181580649	181580672	1	+	26627737	HeLa	viability after 8 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.07737719658807629	[1128]	[522,576,319]	0	hSpCas9	negative selection	1426412
181651357	181651380	1	-	26627737	HeLa	viability after 8 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	1.4105762720504447	[88]	[46,182,68]	8	hSpCas9	negative selection	1426413
181483791	181483814	1	+	26627737	HeLa	viability after 12 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	0.5313344471515477	[162]	[20,161,99]	4	hSpCas9	negative selection	1508717
181510566	181510589	1	-	26627737	HeLa	viability after 12 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.24989288055642478	[637]	[312,148,495]	2	hSpCas9	negative selection	1508718
181511463	181511486	1	-	26627737	HeLa	viability after 12 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.44816818804060365	[620]	[447,191,429]	4	hSpCas9	negative selection	1508719
181577835	181577858	1	-	26627737	HeLa	viability after 12 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	2.0958755979748926	[56]	[25,99,173]	9	hSpCas9	negative selection	1508726
181580649	181580672	1	+	26627737	HeLa	viability after 12 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.691082817802657	[1128]	[266,244,358]	-6	hSpCas9	negative selection	1508727
181651357	181651380	1	-	26627737	HeLa	viability after 12 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.3843459380202774	[88]	[47,85,5]	3	hSpCas9	negative selection	1508728
181483791	181483814	1	+	26627737	HeLa	viability after 15 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	1.609038550742791	[162]	[286,130,186]	9	hSpCas9	negative selection	1591032
181510566	181510589	1	-	26627737	HeLa	viability after 15 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.9623543074166312	[637]	[526,375,623]	7	hSpCas9	negative selection	1591033
181511463	181511486	1	-	26627737	HeLa	viability after 15 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.40328467097227527	[620]	[261,201,556]	3	hSpCas9	negative selection	1591034
181577835	181577858	1	-	26627737	HeLa	viability after 15 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	2.557974002531672	[56]	[140,142,124]	9	hSpCas9	negative selection	1591041
181580649	181580672	1	+	26627737	HeLa	viability after 15 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.16916021496561462	[1128]	[268,454,511]	-1	hSpCas9	negative selection	1591042
181651357	181651380	1	-	26627737	HeLa	viability after 15 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.8699166494752404	[88]	[91,55,48]	6	hSpCas9	negative selection	1591043
181483791	181483814	1	+	26627737	HeLa	viability after 18 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	1.6245460669066993	[162]	[193,111,186]	9	hSpCas9	negative selection	1673347
181510566	181510589	1	-	26627737	HeLa	viability after 18 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.9660572765408151	[637]	[357,308,623]	7	hSpCas9	negative selection	1673348
181511463	181511486	1	-	26627737	HeLa	viability after 18 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.3646103639117184	[620]	[157,167,556]	3	hSpCas9	negative selection	1673349
181577835	181577858	1	-	26627737	HeLa	viability after 18 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	2.546352427521875	[56]	[95,113,124]	9	hSpCas9	negative selection	1673356
181580649	181580672	1	+	26627737	HeLa	viability after 18 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.1384471589114573	[1128]	[182,394,511]	-1	hSpCas9	negative selection	1673357
181651357	181651380	1	-	26627737	HeLa	viability after 18 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.6985626522786097	[88]	[49,42,48]	5	hSpCas9	negative selection	1673358
181483791	181483814	1	+	26627737	HCT116	viability after 6 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-0.22349335984542756	[462]	[149,13]	-1	hSpCas9	negative selection	1755662
181510566	181510589	1	-	26627737	HCT116	viability after 6 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	1.84256758267618	[913]	[388,584]	8	hSpCas9	negative selection	1755663
181511463	181511486	1	-	26627737	HCT116	viability after 6 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-1.4828835307155077	[1079]	[130,21]	-7	hSpCas9	negative selection	1755664
181577835	181577858	1	-	26627737	HCT116	viability after 6 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-1.3392817640062653	[455]	[37,22]	-6	hSpCas9	negative selection	1755671
181580649	181580672	1	+	26627737	HCT116	viability after 6 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	1.227402764266194	[1028]	[167,494]	6	hSpCas9	negative selection	1755672
181651357	181651380	1	-	26627737	HCT116	viability after 6 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.26046407735702687	[578]	[41,145]	1	hSpCas9	negative selection	1755673
181483791	181483814	1	+	26627737	HCT116	viability after 8 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-0.682022655059978	[397]	[115,180,112]	-7	hSpCas9	negative selection	1837977
181510566	181510589	1	-	26627737	HCT116	viability after 8 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	-0.31617091639487627	[1004]	[519,557,259]	-4	hSpCas9	negative selection	1837978
181511463	181511486	1	-	26627737	HCT116	viability after 8 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.3584821859172105	[639]	[315,322,187]	-4	hSpCas9	negative selection	1837979
181577835	181577858	1	-	26627737	HCT116	viability after 8 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	0.18901655708593212	[127]	[63,102,73]	2	hSpCas9	negative selection	1837986
181580649	181580672	1	+	26627737	HCT116	viability after 8 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.34261182051715133	[587]	[377,362,489]	4	hSpCas9	negative selection	1837987
181651357	181651380	1	-	26627737	HCT116	viability after 8 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-1.181110757816326	[268]	[34,130,29]	-9	hSpCas9	negative selection	1837988
181483791	181483814	1	+	26627737	HCT116	viability after 9 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	0.6951468966359123	[462]	[355,76]	5	hSpCas9	negative selection	1920292
181510566	181510589	1	-	26627737	HCT116	viability after 9 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	1.3887946255254389	[913]	[499,748]	8	hSpCas9	negative selection	1920293
181511463	181511486	1	-	26627737	HCT116	viability after 9 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.452434535195371	[1079]	[426,368]	3	hSpCas9	negative selection	1920294
181577835	181577858	1	-	26627737	HCT116	viability after 9 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-1.0583133062748782	[455]	[53,61]	-6	hSpCas9	negative selection	1920301
181580649	181580672	1	+	26627737	HCT116	viability after 9 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.6117737875302142	[1028]	[195,166]	-4	hSpCas9	negative selection	1920302
181651357	181651380	1	-	26627737	HCT116	viability after 9 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.7005233787400583	[578]	[69,114]	-5	hSpCas9	negative selection	1920303
181483791	181483814	1	+	26627737	HCT116	viability after 12 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-0.9477429009481941	[397]	[103,161,60]	-8	hSpCas9	negative selection	2002607
181510566	181510589	1	-	26627737	HCT116	viability after 12 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.04606318979343316	[1004]	[587,622,422]	0	hSpCas9	negative selection	2002608
181511463	181511486	1	-	26627737	HCT116	viability after 12 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.18908262683502008	[639]	[325,321,234]	-2	hSpCas9	negative selection	2002609
181577835	181577858	1	-	26627737	HCT116	viability after 12 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	0.5731241021121178	[127]	[76,171,54]	5	hSpCas9	negative selection	2002616
181580649	181580672	1	+	26627737	HCT116	viability after 12 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.35305244346252374	[587]	[465,361,348]	3	hSpCas9	negative selection	2002617
181651357	181651380	1	-	26627737	HCT116	viability after 12 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-1.71262142943189	[268]	[33,34,60]	-9	hSpCas9	negative selection	2002618
181483791	181483814	1	+	26627737	HCT116	viability after 15 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-0.6714202966585023	[397]	[156,198,76]	-6	hSpCas9	negative selection	2084922
181510566	181510589	1	-	26627737	HCT116	viability after 15 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	-0.31666678804650483	[1004]	[345,568,460]	-3	hSpCas9	negative selection	2084923
181511463	181511486	1	-	26627737	HCT116	viability after 15 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.22418461494169906	[639]	[500,304,489]	2	hSpCas9	negative selection	2084924
181577835	181577858	1	-	26627737	HCT116	viability after 15 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	0.7617534187201436	[127]	[102,119,147]	6	hSpCas9	negative selection	2084931
181580649	181580672	1	+	26627737	HCT116	viability after 15 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.5755981650311424	[587]	[759,277,502]	5	hSpCas9	negative selection	2084932
181651357	181651380	1	-	26627737	HCT116	viability after 15 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.9419779603350614	[268]	[68,102,67]	-7	hSpCas9	negative selection	2084933
181483791	181483814	1	+	26627737	HCT116	viability after 18 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-0.7875093440939929	[397]	[88,149,91]	-6	hSpCas9	negative selection	2167237
181510566	181510589	1	-	26627737	HCT116	viability after 18 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	-0.22099367103931344	[1004]	[323,382,551]	-2	hSpCas9	negative selection	2167238
181511463	181511486	1	-	26627737	HCT116	viability after 18 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.4041359496989345	[639]	[294,501,425]	3	hSpCas9	negative selection	2167239
181577835	181577858	1	-	26627737	HCT116	viability after 18 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	0.6257290484204536	[127]	[102,61,124]	5	hSpCas9	negative selection	2167246
181580649	181580672	1	+	26627737	HCT116	viability after 18 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.6569059112907951	[587]	[715,394,226]	5	hSpCas9	negative selection	2167247
181651357	181651380	1	-	26627737	HCT116	viability after 18 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.8901123194221198	[268]	[11,106,89]	-7	hSpCas9	negative selection	2167248
181633532	181633555	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGCACTGCACTCCAGCCTGGG	CACNA1E	ENSG00000198216	0.14919512582895444	[137,141]	[31,35]	0	dCas9-VP64	positive selection	2409505
181483394	181483417	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGTGTTCAGGGACCAGAGAGG	CACNA1E	ENSG00000198216	2.051787666630101	[114,8]	[99,7]	7	dCas9-VP64	positive selection	2412192
181483349	181483372	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCAAACATAGCTCCTCTTCTGG	CACNA1E	ENSG00000198216	-1.7106559990621502	[730,112]	[36,16]	-8	dCas9-VP64	positive selection	2412193
181483416	181483439	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTTTCAAAATGCCAGTGTGTGG	CACNA1E	ENSG00000198216	-0.08241214638517791	[1436,29]	[285,2]	0	dCas9-VP64	positive selection	2412194
181599122	181599145	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACACACTGGGGCCTATCGGAGG	CACNA1E	ENSG00000198216	1.453933568101652	[32,14]	[18,9]	5	dCas9-VP64	positive selection	2462585
181671234	181671257	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCTGGTCTCAAACTCCTCAG	CACNA1E	ENSG00000198216	1.754298476960665	[131,229]	[162,104]	6	dCas9-VP64	positive selection	2469891
181578522	181578545	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGCCACTGCACTCCAGCCTTGG	CACNA1E	ENSG00000198216	0.6631647882125523	[138,30]	[44,11]	3	dCas9-VP64	positive selection	2473821
181633532	181633555	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGCACTGCACTCCAGCCTGGG	CACNA1E	ENSG00000198216	0.26947116138715255	[117,96]	[23,58]	2	dCas9-VP64	positive selection	2504760
181483394	181483417	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGTGTTCAGGGACCAGAGAGG	CACNA1E	ENSG00000198216	0.5132518168390848	[43,132]	[57,23]	4	dCas9-VP64	positive selection	2507447
181483349	181483372	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCAAACATAGCTCCTCTTCTGG	CACNA1E	ENSG00000198216	0.6725896022549788	[78,153]	[34,82]	5	dCas9-VP64	positive selection	2507448
181483416	181483439	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTTTCAAAATGCCAGTGTGTGG	CACNA1E	ENSG00000198216	-0.6651651271749084	[106,62]	[21,12]	-6	dCas9-VP64	positive selection	2507449
181599122	181599145	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACACACTGGGGCCTATCGGAGG	CACNA1E	ENSG00000198216	1.0550576295542908	[73,85]	[10,93]	6	dCas9-VP64	positive selection	2557840
181671234	181671257	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCTGGTCTCAAACTCCTCAG	CACNA1E	ENSG00000198216	0.3544513964898359	[322,573]	[129,237]	3	dCas9-VP64	positive selection	2565146
181578522	181578545	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGCCACTGCACTCCAGCCTTGG	CACNA1E	ENSG00000198216	-0.07877572482445189	[107,69]	[28,25]	0	dCas9-VP64	positive selection	2569076
181483861	181483884	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAAGCAGACGAAAGCACAGAGG	CACNA1E	ENSG00000198216	0.009786808005391334	[4,4]	[4,3]	0	hSpCas9	positive selection	2975882
181710973	181710996	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGAGAGTGGAGAACCGAAGGG	CACNA1E	ENSG00000198216	0.14817972367663645	[3,3]	[4,2]	3	hSpCas9	positive selection	2975883
181710987	181711010	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTTCATGAAAGCCCTTCGG	CACNA1E	ENSG00000198216	0.006761943239770238	[3,4]	[2,3]	0	hSpCas9	positive selection	2975884
181483839	181483862	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGGCGGCCGCCTGCCCCGAGG	CACNA1E	ENSG00000198216	-0.532371372762817	[2,2]	[1,0]	-7	hSpCas9	positive selection	2975885
181483861	181483884	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAAGCAGACGAAAGCACAGAGG	CACNA1E	ENSG00000198216	0.343228533027992	[4,4]	[5,3]	6	hSpCas9	positive selection	3043740
181710973	181710996	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGAGAGTGGAGAACCGAAGGG	CACNA1E	ENSG00000198216	-0.1617811422789516	[3,3]	[2,1]	-2	hSpCas9	positive selection	3043741
181710987	181711010	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTTCATGAAAGCCCTTCGG	CACNA1E	ENSG00000198216	-0.6860826177130914	[3,3]	[2,0]	-8	hSpCas9	positive selection	3043742
181483839	181483862	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGGCGGCCGCCTGCCCCGAGG	CACNA1E	ENSG00000198216	0.026290679428193964	[2,2]	[3,0]	0	hSpCas9	positive selection	3043743
181577784	181577807		+	24336571	A375	resistance to PLX after 7 days	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.08780175558336722	[37,40]	[42,40]	3	hSpCas9	positive selection	3160178
181511374	181511397		+	24336571	A375	resistance to PLX after 7 days	AAGACAGAACCTTATTTCATTGG	CACNA1E	ENSG00000198216	-0.08409585580741652	[56,58]	[50,56]	-2	hSpCas9	positive selection	3160179
181577842	181577865		-	24336571	A375	resistance to PLX after 7 days	ATCCCTGACACGAGCTTCAAAGG	CACNA1E	ENSG00000198216	-0.018463743713262093	[24,25]	[23,24]	0	hSpCas9	positive selection	3160180
181511488	181511511		+	24336571	A375	resistance to PLX after 7 days	GACTTCATCGTGGTCCTCAGTGG	CACNA1E	ENSG00000198216	-0.006546133215644678	[36,39]	[40,34]	0	hSpCas9	positive selection	3160181
181577784	181577807		+	24336571	A375	resistance to PLX after 14 days	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.2965253169262301	[37,37]	[24,17]	3	hSpCas9	positive selection	3217971
181511374	181511397		+	24336571	A375	resistance to PLX after 14 days	AAGACAGAACCTTATTTCATTGG	CACNA1E	ENSG00000198216	1.7147027323613795	[52,54]	[85,80]	9	hSpCas9	positive selection	3217972
181577842	181577865		-	24336571	A375	resistance to PLX after 14 days	ATCCCTGACACGAGCTTCAAAGG	CACNA1E	ENSG00000198216	-0.22461134397385463	[38,31]	[12,14]	-2	hSpCas9	positive selection	3217973
181511488	181511511		+	24336571	A375	resistance to PLX after 14 days	GACTTCATCGTGGTCCTCAGTGG	CACNA1E	ENSG00000198216	-0.7600319215885596	[45,39]	[11,10]	-8	hSpCas9	positive selection	3217974
181577784	181577807		+	24336571	A375	viability after 7 days	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.16776738077757436	[46]	[37,40]	-2	hSpCas9	negative selection	3275764
181511374	181511397		+	24336571	A375	viability after 7 days	AAGACAGAACCTTATTTCATTGG	CACNA1E	ENSG00000198216	0.1563273618341463	[54]	[56,58]	2	hSpCas9	negative selection	3275765
181577842	181577865		-	24336571	A375	viability after 7 days	ATCCCTGACACGAGCTTCAAAGG	CACNA1E	ENSG00000198216	-0.013501282439060014	[26]	[24,25]	0	hSpCas9	negative selection	3275766
181511488	181511511		+	24336571	A375	viability after 7 days	GACTTCATCGTGGTCCTCAGTGG	CACNA1E	ENSG00000198216	0.17836333119614256	[35]	[36,39]	2	hSpCas9	negative selection	3275767
181577784	181577807		+	24336571	A375	viability after 14 days	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.204027765439168	[46]	[37,37]	-2	hSpCas9	negative selection	3333557
181511374	181511397		+	24336571	A375	viability after 14 days	AAGACAGAACCTTATTTCATTGG	CACNA1E	ENSG00000198216	0.08381562855779512	[54]	[52,54]	1	hSpCas9	negative selection	3333558
181577842	181577865		-	24336571	A375	viability after 14 days	ATCCCTGACACGAGCTTCAAAGG	CACNA1E	ENSG00000198216	0.5066475545982069	[26]	[38,31]	6	hSpCas9	negative selection	3333559
181511488	181511511		+	24336571	A375	viability after 14 days	GACTTCATCGTGGTCCTCAGTGG	CACNA1E	ENSG00000198216	0.3632633148420792	[35]	[45,39]	4	hSpCas9	negative selection	3333560
181577784	181577807	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.3564692704866606	[176,214]	[0,0]	-2	hSpCas9	positive selection	3340723
181579203	181579226	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	-1.033836962413978	[350,274]	[0,0]	-7	hSpCas9	positive selection	3340724
181511433	181511456	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.9822363670197242	[68,85]	[0,0]	4	hSpCas9	positive selection	3340725
181511456	181511479	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.748298337748043	[256,256]	[0,0]	-5	hSpCas9	positive selection	3359976
181577787	181577810	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	-0.16893854325626279	[171,171]	[0,0]	-1	hSpCas9	positive selection	3359977
181579107	181579130	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	-2.147815251690509	[677,677]	[0,0]	-9	hSpCas9	positive selection	3359978
181483860	181483883	1	+	26780180	HT29	viability (Avana library 4 designs)	ACAAGCAGACGAAAGCACAGAGG	CACNA1E	ENSG00000198216	0.505107727286504	[]	[]	2	hSpCas9	negative selection	3412157
181710972	181710995	1	+	26780180	HT29	viability (Avana library 4 designs)	AGAGAGAGTGGAGAACCGAAGGG	CACNA1E	ENSG00000198216	1.43483708732834	[]	[]	5	hSpCas9	negative selection	3412158
181710987	181711010	1	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCTTCATGAAAGCCCTTCGG	CACNA1E	ENSG00000198216	0.449431406400989	[]	[]	1	hSpCas9	negative selection	3412159
181483839	181483862	1	-	26780180	HT29	viability (Avana library 4 designs)	GTAGGCGGCCGCCTGCCCCGAGG	CACNA1E	ENSG00000198216	1.25191190009742	[]	[]	5	hSpCas9	negative selection	3412160
181483839	181483862	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGGCGGCCGCCTGCCCCGAGG	CACNA1E	ENSG00000198216	7.36581583323544	[]	[]	9	hSpCas9	negative selection	3487481
181710972	181710995	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGAGAGTGGAGAACCGAAGGG	CACNA1E	ENSG00000198216	-0.286477682423662	[]	[]	0	hSpCas9	negative selection	3487482
181710987	181711010	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTTCATGAAAGCCCTTCGG	CACNA1E	ENSG00000198216	2.35574731484174	[]	[]	3	hSpCas9	negative selection	3487483
181483860	181483883	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAAGCAGACGAAAGCACAGAGG	CACNA1E	ENSG00000198216	-1.76387952855857	[]	[]	-2	hSpCas9	negative selection	3487484
181511432	181511455	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTATGGAAGATGAACCCCAGGG	CACNA1E	ENSG00000198216	-1.23396244507651	[]	[]	-1	hSpCas9	negative selection	3487485
181720217	181720240	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGACCACCAAATTCCGTAGGG	CACNA1E	ENSG00000198216	-1.17039792216152	[]	[]	-1	hSpCas9	negative selection	3487486
181483839	181483862	1	-	26780180	A375	viability (Avana lentiGuide)	GTAGGCGGCCGCCTGCCCCGAGG	CACNA1E	ENSG00000198216	9.01367550564563	[]	[]	6	hSpCas9	negative selection	3596140
181710972	181710995	1	+	26780180	A375	viability (Avana lentiGuide)	AGAGAGAGTGGAGAACCGAAGGG	CACNA1E	ENSG00000198216	-2.22775569955907	[]	[]	-4	hSpCas9	negative selection	3596141
181710987	181711010	1	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTTCATGAAAGCCCTTCGG	CACNA1E	ENSG00000198216	4.87744077768679	[]	[]	4	hSpCas9	negative selection	3596142
181483860	181483883	1	+	26780180	A375	viability (Avana lentiGuide)	ACAAGCAGACGAAAGCACAGAGG	CACNA1E	ENSG00000198216	1.12367943639357	[]	[]	1	hSpCas9	negative selection	3596143
181511432	181511455	1	-	26780180	A375	viability (Avana lentiGuide)	CTTATGGAAGATGAACCCCAGGG	CACNA1E	ENSG00000198216	-6.63310998731793	[]	[]	-9	hSpCas9	negative selection	3596144
181720217	181720240	1	-	26780180	A375	viability (Avana lentiGuide)	GGAGACCACCAAATTCCGTAGGG	CACNA1E	ENSG00000198216	0.84204797449357	[]	[]	1	hSpCas9	negative selection	3596145
181483839	181483862	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGGCGGCCGCCTGCCCCGAGG	CACNA1E	ENSG00000198216	0.3605030161364796	[4]	[5,5]	9	hSpCas9	positive selection	3704799
181710972	181710995	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGAGAGTGGAGAACCGAAGGG	CACNA1E	ENSG00000198216	0.024491538599036154	[5]	[5,5]	0	hSpCas9	positive selection	3704800
181710987	181711010	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTTCATGAAAGCCCTTCGG	CACNA1E	ENSG00000198216	-0.22352159625852458	[4]	[3,2]	-4	hSpCas9	positive selection	3704801
181483860	181483883	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAAGCAGACGAAAGCACAGAGG	CACNA1E	ENSG00000198216	0.07014807083994365	[5]	[6,5]	1	hSpCas9	positive selection	3704802
181511432	181511455	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTATGGAAGATGAACCCCAGGG	CACNA1E	ENSG00000198216	-0.3757485620600728	[5]	[3,4]	-5	hSpCas9	positive selection	3704803
181720217	181720240	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGACCACCAAATTCCGTAGGG	CACNA1E	ENSG00000198216	-0.21903106468489042	[5]	[4,4]	-3	hSpCas9	positive selection	3704804
181483839	181483862	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGGCGGCCGCCTGCCCCGAGG	CACNA1E	ENSG00000198216	-0.15511670882979112	[4]	[3,3]	-2	hSpCas9	positive selection	3813406
181710972	181710995	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGAGAGTGGAGAACCGAAGGG	CACNA1E	ENSG00000198216	-0.16147606793217745	[5]	[4,2]	-2	hSpCas9	positive selection	3813407
181710987	181711010	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTTCATGAAAGCCCTTCGG	CACNA1E	ENSG00000198216	-0.17779030734091636	[5]	[5,2]	-2	hSpCas9	positive selection	3813408
181483860	181483883	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAAGCAGACGAAAGCACAGAGG	CACNA1E	ENSG00000198216	0.3353436997094219	[6]	[6,7]	8	hSpCas9	positive selection	3813409
181511432	181511455	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTATGGAAGATGAACCCCAGGG	CACNA1E	ENSG00000198216	0.30354208569170854	[5]	[6,5]	8	hSpCas9	positive selection	3813410
181720217	181720240	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGACCACCAAATTCCGTAGGG	CACNA1E	ENSG00000198216	0.07022939526992326	[5]	[6,4]	1	hSpCas9	positive selection	3813411
181577784	181577807	1	+	26780180	A375	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	1.30417514368018	[]	[]	7	hSpCas9	negative selection	3921706
181579107	181579130	1	+	26780180	A375	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.301502838819366	[]	[]	0	hSpCas9	negative selection	3921707
181511433	181511456	1	-	26780180	A375	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	1.06724807102084	[]	[]	5	hSpCas9	negative selection	3921708
181579203	181579226	1	+	26780180	A375	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.8881890375028	[]	[]	4	hSpCas9	negative selection	3921709
181511456	181511479	1	+	26780180	A375	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	1.01979752344073	[]	[]	5	hSpCas9	negative selection	3921710
181577787	181577810	1	-	26780180	A375	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.531918051798059	[]	[]	1	hSpCas9	negative selection	3921711
181577784	181577807	1	+	26780180	HT29	viability (GeCKOv2 library)	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.472628122904858	[]	[]	1	hSpCas9	negative selection	4029672
181579107	181579130	1	+	26780180	HT29	viability (GeCKOv2 library)	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	-0.0423649952653133	[]	[]	-1	hSpCas9	negative selection	4029673
181511433	181511456	1	-	26780180	HT29	viability (GeCKOv2 library)	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.721460681562026	[]	[]	2	hSpCas9	negative selection	4029674
181579203	181579226	1	+	26780180	HT29	viability (GeCKOv2 library)	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	1.17293815291473	[]	[]	5	hSpCas9	negative selection	4029675
181511456	181511479	1	+	26780180	HT29	viability (GeCKOv2 library)	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	0.903382134365307	[]	[]	4	hSpCas9	negative selection	4029676
181577787	181577810	1	-	26780180	HT29	viability (GeCKOv2 library)	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.285506057184278	[]	[]	0	hSpCas9	negative selection	4029677
181577784	181577807	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.11312095148374984	[5]	[3,4]	3	hSpCas9	positive selection	4188246
181511374	181511397	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGACAGAACCTTATTTCATTGG	CACNA1E	ENSG00000198216	0.4718405090583572	[5]	[4,6]	8	hSpCas9	positive selection	4188247
181577842	181577865	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCCCTGACACGAGCTTCAAAGG	CACNA1E	ENSG00000198216	0.22134554259713896	[4]	[3,3]	5	hSpCas9	positive selection	4188248
181511488	181511511	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACTTCATCGTGGTCCTCAGTGG	CACNA1E	ENSG00000198216	0.011589154686665992	[5]	[3,3]	0	hSpCas9	positive selection	4188249
181577784	181577807	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	1.26517730752397	[5]	[5,5,2,7]	9	hSpCas9	positive selection	4252268
181511374	181511397	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGACAGAACCTTATTTCATTGG	CACNA1E	ENSG00000198216	0.9957202783623169	[5]	[5,4,3,5]	7	hSpCas9	positive selection	4252269
181577842	181577865	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCCCTGACACGAGCTTCAAAGG	CACNA1E	ENSG00000198216	0.314142810509672	[4]	[1,6,3,0]	2	hSpCas9	positive selection	4252270
181511488	181511511	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACTTCATCGTGGTCCTCAGTGG	CACNA1E	ENSG00000198216	0.3839868144890571	[4]	[3,4,4,0]	3	hSpCas9	positive selection	4252271
181577784	181577807	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.3119948134678716	[3]	[2,0]	-6	hSpCas9	positive selection	4260587
181579203	181579226	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.05335130922020437	[3]	[3,2]	1	hSpCas9	positive selection	4260588
181511433	181511456	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.009055323584434255	[2]	[1,1]	0	hSpCas9	positive selection	4260589
181511456	181511479	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	0.3515497309208454	[3]	[3,4]	7	hSpCas9	positive selection	4324868
181577787	181577810	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.18714873030838042	[1]	[2,0]	4	hSpCas9	positive selection	4324869
181579107	181579130	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.5442117569130529	[4]	[5,5]	9	hSpCas9	positive selection	4324870
181726152	181726174	1	-	27760321	OCIAML3	viability	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	0.9004458019387354	[69,39]	[63,97]	9	hSpCas9	negative selection	4385103
181732557	181732579	1	-	27760321	OCIAML3	viability	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.3593603671874932	[403,357]	[388,371]	4	hSpCas9	negative selection	4385104
181732854	181732876	1	+	27760321	OCIAML3	viability	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.2588538176305518	[478,417]	[416,420]	3	hSpCas9	negative selection	4385105
181733654	181733676	1	+	27760321	OCIAML3	viability	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	0.428608114077379	[587,472]	[352,818]	5	hSpCas9	negative selection	4385106
181733708	181733730	1	+	27760321	OCIAML3	viability	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.8697508078512742	[733,578]	[824,1071]	8	hSpCas9	negative selection	4385107
181726152	181726174	1	-	27760321	OCIAML2	viability	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	0.22204494227683202	[69,39]	[43,59]	3	hSpCas9	negative selection	4468566
181732557	181732579	1	-	27760321	OCIAML2	viability	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.1573136576593798	[403,357]	[362,316]	2	hSpCas9	negative selection	4468567
181732854	181732876	1	+	27760321	OCIAML2	viability	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	-0.18638008285042032	[478,417]	[217,449]	-2	hSpCas9	negative selection	4468568
181733654	181733676	1	+	27760321	OCIAML2	viability	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	0.4220309150980085	[587,472]	[585,552]	6	hSpCas9	negative selection	4468569
181733708	181733730	1	+	27760321	OCIAML2	viability	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.36332011349325344	[733,578]	[582,804]	5	hSpCas9	negative selection	4468570
181726152	181726174	1	-	27760321	MV411	viability	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	0.5513167610185783	[69,39]	[16,104]	4	hSpCas9	negative selection	4552029
181732557	181732579	1	-	27760321	MV411	viability	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	1.3951402096276828	[403,357]	[624,712]	8	hSpCas9	negative selection	4552030
181732854	181732876	1	+	27760321	MV411	viability	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.2273338680785755	[478,417]	[443,197]	1	hSpCas9	negative selection	4552031
181733654	181733676	1	+	27760321	MV411	viability	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	0.37866332802855585	[587,472]	[444,463]	2	hSpCas9	negative selection	4552032
181733708	181733730	1	+	27760321	MV411	viability	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.14826034366489638	[733,578]	[522,407]	1	hSpCas9	negative selection	4552033
181726152	181726174	1	-	27760321	HL60	viability	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	-0.711539517176452	[69,39]	[23,29]	-6	hSpCas9	negative selection	4635492
181732557	181732579	1	-	27760321	HL60	viability	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.5078487042897052	[403,357]	[335,553]	6	hSpCas9	negative selection	4635493
181732854	181732876	1	+	27760321	HL60	viability	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.25765320560924054	[478,417]	[436,436]	3	hSpCas9	negative selection	4635494
181733654	181733676	1	+	27760321	HL60	viability	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	0.4046607071123577	[587,472]	[551,589]	5	hSpCas9	negative selection	4635495
181733708	181733730	1	+	27760321	HL60	viability	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.4358326451759357	[733,578]	[646,798]	5	hSpCas9	negative selection	4635496
181726152	181726174	1	-	27760321	HT1080	viability	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	-3.8213028996417866	[39,30]	[0,0]	-8	hSpCas9	negative selection	4718955
181732557	181732579	1	-	27760321	HT1080	viability	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.873149067188191	[357,279]	[217,248]	5	hSpCas9	negative selection	4718956
181732854	181732876	1	+	27760321	HT1080	viability	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	1.4903698292507368	[417,325]	[507,315]	7	hSpCas9	negative selection	4718957
181733654	181733676	1	+	27760321	HT1080	viability	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	1.6946542408217469	[472,368]	[613,464]	8	hSpCas9	negative selection	4718958
181733708	181733730	1	+	27760321	HT1080	viability	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.5885669504804821	[578,451]	[325,289]	3	hSpCas9	negative selection	4718959
181726152	181726174	1	-	27760321	HT29	viability after 7 days	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	0.4697251688872006	[39,30]	[96,88,9]	7	hSpCas9	negative selection	4802418
181732557	181732579	1	-	27760321	HT29	viability after 7 days	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.17478718610766267	[357,279]	[376,594,405]	2	hSpCas9	negative selection	4802419
181732854	181732876	1	+	27760321	HT29	viability after 7 days	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.17889992262167587	[417,325]	[571,234,811]	2	hSpCas9	negative selection	4802420
181733654	181733676	1	+	27760321	HT29	viability after 7 days	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	0.6528087070348731	[472,368]	[1159,812,629]	8	hSpCas9	negative selection	4802421
181733708	181733730	1	+	27760321	HT29	viability after 7 days	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.45819481322649547	[578,451]	[1076,985,697]	7	hSpCas9	negative selection	4802422
181726152	181726174	1	-	27760321	HT29	viability after 25 days	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	1.176338150800095	[39,30]	[89,126,53]	9	hSpCas9	negative selection	4885881
181732557	181732579	1	-	27760321	HT29	viability after 25 days	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.6725834431076478	[357,279]	[415,729,609]	7	hSpCas9	negative selection	4885882
181732854	181732876	1	+	27760321	HT29	viability after 25 days	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.414420517284577	[417,325]	[616,405,684]	4	hSpCas9	negative selection	4885883
181733654	181733676	1	+	27760321	HT29	viability after 25 days	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	1.2237328588919993	[472,368]	[846,1326,1222]	9	hSpCas9	negative selection	4885884
181733708	181733730	1	+	27760321	HT29	viability after 25 days	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.8414520338490218	[578,451]	[526,1405,1289]	8	hSpCas9	negative selection	4885885
181726152	181726174	1	-	27760321	HT29	viability after 22 days	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	0.5572040365369486	[39,30]	[120,43,13]	6	hSpCas9	negative selection	4969344
181732557	181732579	1	-	27760321	HT29	viability after 22 days	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.5320723537683105	[357,279]	[253,977,373]	6	hSpCas9	negative selection	4969345
181732854	181732876	1	+	27760321	HT29	viability after 22 days	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.6095972580570489	[417,325]	[686,478,802]	6	hSpCas9	negative selection	4969346
181733654	181733676	1	+	27760321	HT29	viability after 22 days	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	1.2492730745380176	[472,368]	[1082,1212,1176]	9	hSpCas9	negative selection	4969347
181733708	181733730	1	+	27760321	HT29	viability after 22 days	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.834372549475992	[578,451]	[710,1251,1235]	8	hSpCas9	negative selection	4969348
181726152	181726174	1	-	27760321	HT29	viability after 19 days	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	0.8069324066037962	[39,30]	[81,111,21]	8	hSpCas9	negative selection	5052807
181732557	181732579	1	-	27760321	HT29	viability after 19 days	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.3950534346428368	[357,279]	[533,516,396]	4	hSpCas9	negative selection	5052808
181732854	181732876	1	+	27760321	HT29	viability after 19 days	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.4140496009226089	[417,325]	[593,407,695]	4	hSpCas9	negative selection	5052809
181733654	181733676	1	+	27760321	HT29	viability after 19 days	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	1.4892468017328502	[472,368]	[705,1751,1521]	9	hSpCas9	negative selection	5052810
181733708	181733730	1	+	27760321	HT29	viability after 19 days	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	1.0240990423648495	[578,451]	[724,1284,1523]	9	hSpCas9	negative selection	5052811
181726152	181726174	1	-	27760321	HT29	viability after 16 days	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	1.6588646886807175	[39,30]	[127,98,149]	9	hSpCas9	negative selection	5136270
181732557	181732579	1	-	27760321	HT29	viability after 16 days	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.5729505088306251	[357,279]	[476,329,785]	6	hSpCas9	negative selection	5136271
181732854	181732876	1	+	27760321	HT29	viability after 16 days	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.3717271428166499	[417,325]	[647,489,488]	4	hSpCas9	negative selection	5136272
181733654	181733676	1	+	27760321	HT29	viability after 16 days	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	0.7173842329300731	[472,368]	[719,812,783]	8	hSpCas9	negative selection	5136273
181733708	181733730	1	+	27760321	HT29	viability after 16 days	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.8493446665165049	[578,451]	[738,956,1394]	8	hSpCas9	negative selection	5136274
181726152	181726174	1	-	27760321	HT29	viability after 13 days	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	0.19109304185086895	[39,30]	[88,40,12]	2	hSpCas9	negative selection	5219733
181732557	181732579	1	-	27760321	HT29	viability after 13 days	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.2101321365757841	[357,279]	[386,409,483]	2	hSpCas9	negative selection	5219734
181732854	181732876	1	+	27760321	HT29	viability after 13 days	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.257954995816822	[417,325]	[563,469,513]	3	hSpCas9	negative selection	5219735
181733654	181733676	1	+	27760321	HT29	viability after 13 days	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	0.6149994534472557	[472,368]	[899,586,755]	7	hSpCas9	negative selection	5219736
181733708	181733730	1	+	27760321	HT29	viability after 13 days	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.8607003318184309	[578,451]	[746,1176,1319]	9	hSpCas9	negative selection	5219737
181726152	181726174	1	-	27760321	HT29	viability after 10 days	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	-0.04607622505813813	[39,30]	[74,33,19]	0	hSpCas9	negative selection	5303196
181732557	181732579	1	-	27760321	HT29	viability after 10 days	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.6037618460233727	[357,279]	[552,709,556]	7	hSpCas9	negative selection	5303197
181732854	181732876	1	+	27760321	HT29	viability after 10 days	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	0.34805875085521243	[417,325]	[778,378,608]	5	hSpCas9	negative selection	5303198
181733654	181733676	1	+	27760321	HT29	viability after 10 days	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	0.8114501214014254	[472,368]	[856,946,962]	9	hSpCas9	negative selection	5303199
181733708	181733730	1	+	27760321	HT29	viability after 10 days	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	0.7268129480967959	[578,451]	[1239,1037,919]	8	hSpCas9	negative selection	5303200
181726152	181726174	1	-	27760321	MOLM13	viability	AGCTGACTCACTCGATCGAAGG	CACNA1E	ENSG00000198216	-0.7044741332963693	[69,39]	[22,14]	-4	hSpCas9	negative selection	5386659
181732557	181732579	1	-	27760321	MOLM13	viability	CTGGGTCGCCGATAAAGGCTGG	CACNA1E	ENSG00000198216	0.9564098280119756	[403,357]	[672,197]	6	hSpCas9	negative selection	5386660
181732854	181732876	1	+	27760321	MOLM13	viability	ATCGCCGCGTCAGGACAGAAGG	CACNA1E	ENSG00000198216	-0.5201320498881497	[478,417]	[235,124]	-3	hSpCas9	negative selection	5386661
181733654	181733676	1	+	27760321	MOLM13	viability	ATCACGGCCAACACGGACAAGG	CACNA1E	ENSG00000198216	1.1106914862745647	[587,472]	[1049,295]	7	hSpCas9	negative selection	5386662
181733708	181733730	1	+	27760321	MOLM13	viability	ATCCCCGACGTGGACCCCTTGG	CACNA1E	ENSG00000198216	1.0506344917518184	[733,578]	[851,685]	7	hSpCas9	negative selection	5386663
181483336	181483359	1	+	27661255	K562	viability	GGTGGTGCGTCTGCCAGAAGAGG	CACNA1E	ENSG00000198216	0.013289398192894541	[1428,1547]	[1376,1045]	0	dCas9-KRAB	negative selection	5467686
181483600	181483623	1	+	27661255	K562	viability	GAGCTCGCGGAGCTCCCCAGAGG	CACNA1E	ENSG00000198216	0.8419623233311342	[121,192]	[227,219]	9	dCas9-KRAB	negative selection	5467687
181483096	181483119	1	-	27661255	K562	viability	GCCAGCAGAGACGCATCCAAAGG	CACNA1E	ENSG00000198216	-0.2244130011802976	[789,737]	[522,522]	-6	dCas9-KRAB	negative selection	5467688
181483590	181483613	1	-	27661255	K562	viability	GCTCCGCGAGCTCTTCGGAGAGG	CACNA1E	ENSG00000198216	-0.17981058677595962	[141,100]	[96,76]	-5	dCas9-KRAB	negative selection	5467689
181577784	181577807	1	+	27260156	BXPC3	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.037949363878326425	[599]	[619,620,571,777]	0	hSpCas9	negative selection	5533047
181579203	181579226	1	+	27260156	BXPC3	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.4366557885589507	[840]	[1116,1029,1247,1401]	8	hSpCas9	negative selection	5533048
181511433	181511456	1	-	27260156	BXPC3	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.031061283471279122	[287]	[325,323,322,244]	0	hSpCas9	negative selection	5533049
181511456	181511479	1	+	27260156	BXPC3	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.10670419446725277	[885]	[735,874,797,1062]	-2	hSpCas9	negative selection	5597328
181577787	181577810	1	-	27260156	BXPC3	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.120023223537847	[147]	[326,304,275,450]	9	hSpCas9	negative selection	5597329
181579107	181579130	1	+	27260156	BXPC3	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.37549136082969015	[1371]	[1513,1782,1966,2260]	7	hSpCas9	negative selection	5597330
181577784	181577807	1	+	27260156	A673	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.030668379340676233	[599]	[783,673,684,810]	0	hSpCas9	negative selection	5654298
181579203	181579226	1	+	27260156	A673	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.3267355511467317	[840]	[1282,1302,1092,1393]	7	hSpCas9	negative selection	5654299
181511433	181511456	1	-	27260156	A673	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.31844530996995657	[287]	[538,372,384,441]	7	hSpCas9	negative selection	5654300
181511456	181511479	1	+	27260156	A673	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.11551098475253274	[885]	[1147,854,899,1049]	-3	hSpCas9	negative selection	5718579
181577787	181577810	1	-	27260156	A673	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.28081504185355	[147]	[493,466,418,347]	9	hSpCas9	negative selection	5718580
181579107	181579130	1	+	27260156	A673	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.27601562714082784	[1371]	[2227,1721,2069,1987]	6	hSpCas9	negative selection	5718581
181577784	181577807	1	+	27260156	A375	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.09095347094860445	[599]	[602,809,559,674]	-1	hSpCas9	negative selection	5775549
181579203	181579226	1	+	27260156	A375	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.44040157531338553	[840]	[1127,1701,1394,1170]	6	hSpCas9	negative selection	5775550
181511433	181511456	1	-	27260156	A375	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.3921176922239238	[287]	[297,204,299,218]	-5	hSpCas9	negative selection	5775551
181511456	181511479	1	+	27260156	A375	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.24789690736234804	[885]	[836,890,950,812]	-4	hSpCas9	negative selection	5839830
181577787	181577810	1	-	27260156	A375	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.868331842990488	[147]	[379,277,316,284]	9	hSpCas9	negative selection	5839831
181579107	181579130	1	+	27260156	A375	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.5485076116450072	[1371]	[2212,2353,2572,2238]	7	hSpCas9	negative selection	5839832
181577784	181577807	1	+	27260156	COLO741	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.06691881326096488	[599]	[802,727,870]	1	hSpCas9	negative selection	5896800
181579203	181579226	1	+	27260156	COLO741	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.34949013324117806	[840]	[1361,1321,1415]	7	hSpCas9	negative selection	5896801
181511433	181511456	1	-	27260156	COLO741	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.18834869108385777	[287]	[304,343,317]	-4	hSpCas9	negative selection	5896802
181511456	181511479	1	+	27260156	COLO741	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	0.009327453940748742	[885]	[1247,1014,1159]	0	hSpCas9	negative selection	5961081
181577787	181577810	1	-	27260156	COLO741	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.5105371785291646	[147]	[553,573,491]	9	hSpCas9	negative selection	5961082
181579107	181579130	1	+	27260156	COLO741	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.25727093316865735	[1371]	[2378,1823,2100]	5	hSpCas9	negative selection	5961083
181577784	181577807	1	+	27260156	CAL120	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.04650843466410287	[599]	[594,1061,631]	0	hSpCas9	negative selection	6018051
181579203	181579226	1	+	27260156	CAL120	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5870707084326364	[840]	[1971,1075,1724]	8	hSpCas9	negative selection	6018052
181511433	181511456	1	-	27260156	CAL120	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.08393159429441344	[287]	[661,231,171]	-1	hSpCas9	negative selection	6018053
181511456	181511479	1	+	27260156	CAL120	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.14585760575213624	[885]	[1242,998,787]	-2	hSpCas9	negative selection	6082332
181577787	181577810	1	-	27260156	CAL120	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.0996073549839058	[147]	[450,328,411]	9	hSpCas9	negative selection	6082333
181579107	181579130	1	+	27260156	CAL120	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.22677817238623965	[1371]	[1826,2354,1788]	3	hSpCas9	negative selection	6082334
181577784	181577807	1	+	27260156	CADOES1	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.18103018846609703	[599]	[534,447,536,446]	-3	hSpCas9	negative selection	6139302
181579203	181579226	1	+	27260156	CADOES1	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5534479578287786	[840]	[1205,917,1471,988]	8	hSpCas9	negative selection	6139303
181511433	181511456	1	-	27260156	CADOES1	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.06366807692347953	[287]	[242,154,267,362]	-1	hSpCas9	negative selection	6139304
181511456	181511479	1	+	27260156	CADOES1	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	0.02859965251154928	[885]	[722,826,980,830]	0	hSpCas9	negative selection	6203583
181577787	181577810	1	-	27260156	CADOES1	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.2222626665860246	[147]	[199,387,274,425]	9	hSpCas9	negative selection	6203584
181579107	181579130	1	+	27260156	CADOES1	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.6352493092853952	[1371]	[2033,2032,1822,2039]	9	hSpCas9	negative selection	6203585
181577784	181577807	1	+	27260156	EWS502	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.05946535808988934	[599]	[596,656,509,675]	-1	hSpCas9	negative selection	6260553
181579203	181579226	1	+	27260156	EWS502	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.29685507210302176	[840]	[1103,985,1296,983]	5	hSpCas9	negative selection	6260554
181511433	181511456	1	-	27260156	EWS502	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.10204064847728578	[287]	[287,249,532,241]	1	hSpCas9	negative selection	6260555
181511456	181511479	1	+	27260156	EWS502	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.2689096244705077	[885]	[1012,696,655,714]	-5	hSpCas9	negative selection	6324834
181577787	181577810	1	-	27260156	EWS502	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.093721648224924	[147]	[258,327,307,459]	9	hSpCas9	negative selection	6324835
181579107	181579130	1	+	27260156	EWS502	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.3648726442551382	[1371]	[1928,1653,1983,1917]	6	hSpCas9	negative selection	6324836
181577784	181577807	1	+	27260156	EW8	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.30619021695792414	[599]	[1106,460,403,519]	5	hSpCas9	negative selection	6381804
181579203	181579226	1	+	27260156	EW8	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.54892026301186	[840]	[997,1277,767,981]	8	hSpCas9	negative selection	6381805
181511433	181511456	1	-	27260156	EW8	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.020833815222269902	[287]	[247,294,195,215]	0	hSpCas9	negative selection	6381806
181511456	181511479	1	+	27260156	EW8	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.029412934418018732	[885]	[893,851,521,596]	0	hSpCas9	negative selection	6446085
181577787	181577810	1	-	27260156	EW8	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.1392013133058545	[147]	[381,226,173,300]	9	hSpCas9	negative selection	6446086
181579107	181579130	1	+	27260156	EW8	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.3120386916571476	[1371]	[1846,1270,1117,1376]	6	hSpCas9	negative selection	6446087
181577784	181577807	1	+	27260156	CORL105	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.18615041516570974	[599]	[761,866,1018,580]	3	hSpCas9	negative selection	6503055
181579203	181579226	1	+	27260156	CORL105	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.4445244845889206	[840]	[1227,1740,1168,1182]	7	hSpCas9	negative selection	6503056
181511433	181511456	1	-	27260156	CORL105	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.22577793451628292	[287]	[302,437,451,388]	4	hSpCas9	negative selection	6503057
181511456	181511479	1	+	27260156	CORL105	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.034214322851013335	[885]	[1131,860,1298,811]	0	hSpCas9	negative selection	6567336
181577787	181577810	1	-	27260156	CORL105	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.3473547911614532	[147]	[359,363,619,445]	9	hSpCas9	negative selection	6567337
181579107	181579130	1	+	27260156	CORL105	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.2253157472093319	[1371]	[1918,1601,2240,1811]	4	hSpCas9	negative selection	6567338
181577784	181577807	1	+	27260156	HS294T	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.1511140819987794	[599]	[218,215,330,270]	2	hSpCas9	negative selection	6624306
181579203	181579226	1	+	27260156	HS294T	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.1845093005802193	[840]	[409,268,384,420]	2	hSpCas9	negative selection	6624307
181511433	181511456	1	-	27260156	HS294T	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.5630034796419503	[287]	[75,49,85,92]	-7	hSpCas9	negative selection	6624308
181511456	181511479	1	+	27260156	HS294T	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.10196141338380205	[885]	[269,279,401,331]	-1	hSpCas9	negative selection	6688587
181577787	181577810	1	-	27260156	HS294T	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	2.0106048875075846	[147]	[134,214,307,281]	9	hSpCas9	negative selection	6688588
181579107	181579130	1	+	27260156	HS294T	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.8249226390265847	[1371]	[734,1347,756,917]	9	hSpCas9	negative selection	6688589
181577784	181577807	1	+	27260156	HCC44	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.19115581553455985	[599]	[1228,387,741,822]	3	hSpCas9	negative selection	6745557
181579203	181579226	1	+	27260156	HCC44	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5106327959757572	[840]	[1192,1336,1751,1188]	8	hSpCas9	negative selection	6745558
181511433	181511456	1	-	27260156	HCC44	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.167812250826471	[287]	[336,277,538,346]	2	hSpCas9	negative selection	6745559
181511456	181511479	1	+	27260156	HCC44	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.033780420433529024	[885]	[987,829,1141,996]	0	hSpCas9	negative selection	6809838
181577787	181577810	1	-	27260156	HCC44	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.021352792606712	[147]	[426,321,350,270]	9	hSpCas9	negative selection	6809839
181579107	181579130	1	+	27260156	HCC44	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.22691809832149978	[1371]	[1650,1808,2079,1742]	3	hSpCas9	negative selection	6809840
181577784	181577807	1	+	27260156	G402	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.45150035192792126	[599]	[1065,1012,1274,672]	5	hSpCas9	negative selection	6866808
181579203	181579226	1	+	27260156	G402	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.18545801505811432	[840]	[1298,837,1353,1171]	2	hSpCas9	negative selection	6866809
181511433	181511456	1	-	27260156	G402	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.04911385086711051	[287]	[372,260,117,592]	0	hSpCas9	negative selection	6866810
181511456	181511479	1	+	27260156	G402	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	0.20408175764301206	[885]	[1599,915,786,1683]	2	hSpCas9	negative selection	6931089
181577787	181577810	1	-	27260156	G402	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.313738903976556	[147]	[433,361,695,301]	9	hSpCas9	negative selection	6931090
181579107	181579130	1	+	27260156	G402	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.7176491864581942	[1371]	[2897,3001,2997,2167]	8	hSpCas9	negative selection	6931091
181577784	181577807	1	+	27260156	L33	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.3510530328183151	[599]	[830,328,549,552]	7	hSpCas9	negative selection	6988059
181579203	181579226	1	+	27260156	L33	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.08166112797402325	[840]	[868,405,570,792]	1	hSpCas9	negative selection	6988060
181511433	181511456	1	-	27260156	L33	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.47108245619847855	[287]	[200,40,147,293]	-8	hSpCas9	negative selection	6988061
181511456	181511479	1	+	27260156	L33	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.2012548523432146	[885]	[751,235,576,836]	-4	hSpCas9	negative selection	7052340
181577787	181577810	1	-	27260156	L33	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.38737587985014	[147]	[359,155,317,303]	9	hSpCas9	negative selection	7052341
181579107	181579130	1	+	27260156	L33	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.09903577689333876	[1371]	[1529,605,907,1422]	2	hSpCas9	negative selection	7052342
181577784	181577807	1	+	27260156	K562	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.22645623433545314	[599]	[947,331,226,356]	-3	hSpCas9	negative selection	7109310
181579203	181579226	1	+	27260156	K562	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.8034976676809963	[840]	[1319,2189,1026,777]	8	hSpCas9	negative selection	7109311
181511433	181511456	1	-	27260156	K562	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.6010266550294598	[287]	[302,108,117,152]	-6	hSpCas9	negative selection	7109312
181511456	181511479	1	+	27260156	K562	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.2768577685843967	[885]	[839,805,623,378]	-3	hSpCas9	negative selection	7173591
181577787	181577810	1	-	27260156	K562	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.6330388400357219	[147]	[178,521,524,390]	9	hSpCas9	negative selection	7173592
181579107	181579130	1	+	27260156	K562	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.19984314418058613	[1371]	[1534,1623,1271,1202]	2	hSpCas9	negative selection	7173593
181577784	181577807	1	+	27260156	HT29	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.01442632351639972	[599]	[664,908,615,757]	0	hSpCas9	negative selection	7230561
181579203	181579226	1	+	27260156	HT29	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.39160621305442833	[840]	[1497,1513,1210,1178]	7	hSpCas9	negative selection	7230562
181511433	181511456	1	-	27260156	HT29	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.216115759034409	[287]	[484,540,295,328]	4	hSpCas9	negative selection	7230563
181511456	181511479	1	+	27260156	HT29	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	0.05873442758122094	[885]	[1048,1265,1185,999]	1	hSpCas9	negative selection	7294842
181577787	181577810	1	-	27260156	HT29	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.2332934478489712	[147]	[474,590,305,344]	9	hSpCas9	negative selection	7294843
181579107	181579130	1	+	27260156	HT29	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.502069952807114	[1371]	[2506,2812,2186,2016]	8	hSpCas9	negative selection	7294844
181577784	181577807	1	+	27260156	MHHES1	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.18595946967813715	[599]	[696,916,984,523]	3	hSpCas9	negative selection	7351812
181579203	181579226	1	+	27260156	MHHES1	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5038868496212846	[840]	[1512,1732,1310,939]	8	hSpCas9	negative selection	7351813
181511433	181511456	1	-	27260156	MHHES1	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.1050783228426041	[287]	[268,326,415,360]	2	hSpCas9	negative selection	7351814
181511456	181511479	1	+	27260156	MHHES1	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.25891681829509205	[885]	[645,1023,840,807]	-5	hSpCas9	negative selection	7416093
181577787	181577810	1	-	27260156	MHHES1	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.9981626512800883	[147]	[319,336,363,307]	9	hSpCas9	negative selection	7416094
181579107	181579130	1	+	27260156	MHHES1	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.29234970907857427	[1371]	[2004,2025,2008,1585]	5	hSpCas9	negative selection	7416095
181577784	181577807	1	+	27260156	MEWO	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.3022182667910146	[599]	[1072,503,573]	6	hSpCas9	negative selection	7473063
181579203	181579226	1	+	27260156	MEWO	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.23828248769029325	[840]	[1188,858,786]	5	hSpCas9	negative selection	7473064
181511433	181511456	1	-	27260156	MEWO	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.46377957517120866	[287]	[621,213,327]	8	hSpCas9	negative selection	7473065
181511456	181511479	1	+	27260156	MEWO	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.1435487074510856	[885]	[1021,679,601]	-3	hSpCas9	negative selection	7537344
181577787	181577810	1	-	27260156	MEWO	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.386738758935302	[147]	[540,315,263]	9	hSpCas9	negative selection	7537345
181579107	181579130	1	+	27260156	MEWO	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.25413027669688915	[1371]	[1830,1388,1430]	5	hSpCas9	negative selection	7537346
181577784	181577807	1	+	27260156	LNCAPCLONEFGC	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.16096665524956622	[599]	[404,392,526,632]	-3	hSpCas9	negative selection	7594314
181579203	181579226	1	+	27260156	LNCAPCLONEFGC	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5591313865056707	[840]	[1058,1268,1205,958]	8	hSpCas9	negative selection	7594315
181511433	181511456	1	-	27260156	LNCAPCLONEFGC	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.04611999917422638	[287]	[163,203,318,403]	0	hSpCas9	negative selection	7594316
181511456	181511479	1	+	27260156	LNCAPCLONEFGC	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	0.10147316461475198	[885]	[771,671,1184,876]	1	hSpCas9	negative selection	7658595
181577787	181577810	1	-	27260156	LNCAPCLONEFGC	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.8695557119605046	[147]	[211,247,331,200]	9	hSpCas9	negative selection	7658596
181579107	181579130	1	+	27260156	LNCAPCLONEFGC	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.5269990433995646	[1371]	[1664,1379,2661,1613]	8	hSpCas9	negative selection	7658597
181577784	181577807	1	+	27260156	PANC0327	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.058268122097001995	[599]	[603,562,323,556]	-1	hSpCas9	negative selection	7715565
181579203	181579226	1	+	27260156	PANC0327	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.6113888114853671	[840]	[1377,657,928,1680]	8	hSpCas9	negative selection	7715566
181511433	181511456	1	-	27260156	PANC0327	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.4202224060766461	[287]	[595,340,182,269]	6	hSpCas9	negative selection	7715567
181511456	181511479	1	+	27260156	PANC0327	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.008243142601306985	[885]	[901,700,1067,479]	0	hSpCas9	negative selection	7779846
181577787	181577810	1	-	27260156	PANC0327	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.9875457949771648	[147]	[273,205,363,206]	9	hSpCas9	negative selection	7779847
181579107	181579130	1	+	27260156	PANC0327	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.4013878212119406	[1371]	[1612,1523,1768,1543]	6	hSpCas9	negative selection	7779848
181577784	181577807	1	+	27260156	NCIH2009	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.17831745837870927	[599]	[971,1100,772]	2	hSpCas9	negative selection	7836816
181579203	181579226	1	+	27260156	NCIH2009	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5982386468665285	[840]	[1862,1670,1817]	7	hSpCas9	negative selection	7836817
181511433	181511456	1	-	27260156	NCIH2009	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.26327709493526597	[287]	[405,290,322]	-4	hSpCas9	negative selection	7836818
181511456	181511479	1	+	27260156	NCIH2009	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.19088768149912494	[885]	[1214,993,1069]	-3	hSpCas9	negative selection	7901097
181577787	181577810	1	-	27260156	NCIH2009	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.7589048457619629	[147]	[409,295,355]	9	hSpCas9	negative selection	7901098
181579107	181579130	1	+	27260156	NCIH2009	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.47930743047898816	[1371]	[2971,3090,2000]	6	hSpCas9	negative selection	7901099
181577784	181577807	1	+	27260156	NCIH1373	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.3367661080794977	[599]	[686,419,509,143]	-3	hSpCas9	negative selection	7958067
181579203	181579226	1	+	27260156	NCIH1373	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.9227230798342748	[840]	[2470,1006,2050,471]	8	hSpCas9	negative selection	7958068
181511433	181511456	1	-	27260156	NCIH1373	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.4328791219402499	[287]	[194,144,116,136]	-4	hSpCas9	negative selection	7958069
181511456	181511479	1	+	27260156	NCIH1373	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.053357000446446756	[885]	[895,928,1170,211]	0	hSpCas9	negative selection	8022348
181577787	181577810	1	-	27260156	NCIH1373	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.20163629550848627	[147]	[254,125,168,60]	2	hSpCas9	negative selection	8022349
181579107	181579130	1	+	27260156	NCIH1373	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.7720378344982628	[1371]	[2186,2171,2967,832]	7	hSpCas9	negative selection	8022350
181577784	181577807	1	+	27260156	PATU8902	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.19040133863232703	[599]	[797,903,462,840]	-2	hSpCas9	negative selection	8079318
181579203	181579226	1	+	27260156	PATU8902	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.8629962754019452	[840]	[2179,2337,2117,1835]	8	hSpCas9	negative selection	8079319
181511433	181511456	1	-	27260156	PATU8902	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.6658552786064551	[287]	[342,122,311,208]	-6	hSpCas9	negative selection	8079320
181511456	181511479	1	+	27260156	PATU8902	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.19792763577321626	[885]	[1323,820,1006,1166]	-2	hSpCas9	negative selection	8143599
181577787	181577810	1	-	27260156	PATU8902	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.6510389164482442	[147]	[102,447,215,587]	7	hSpCas9	negative selection	8143600
181579107	181579130	1	+	27260156	PATU8902	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.8181265749717179	[1371]	[3748,2727,2557,4786]	8	hSpCas9	negative selection	8143601
181577784	181577807	1	+	27260156	PANC1	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.08866569049223683	[599]	[471,866,483,443]	1	hSpCas9	negative selection	8200569
181579203	181579226	1	+	27260156	PANC1	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.3896964149921659	[840]	[830,1200,861,931]	6	hSpCas9	negative selection	8200570
181511433	181511456	1	-	27260156	PANC1	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.6162247467258389	[287]	[364,217,432,449]	8	hSpCas9	negative selection	8200571
181511456	181511479	1	+	27260156	PANC1	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	0.3027769268579579	[885]	[910,1197,1065,664]	5	hSpCas9	negative selection	8264850
181577787	181577810	1	-	27260156	PANC1	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.7123816938239464	[147]	[381,748,354,266]	9	hSpCas9	negative selection	8264851
181579107	181579130	1	+	27260156	PANC1	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.41020941922761445	[1371]	[1509,2190,1563,1168]	6	hSpCas9	negative selection	8264852
181577784	181577807	1	+	27260156	PANC0813	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.20734129578315097	[599]	[1002,808,503,945]	3	hSpCas9	negative selection	8321820
181579203	181579226	1	+	27260156	PANC0813	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.4374728958884516	[840]	[1329,1354,1338,1324]	7	hSpCas9	negative selection	8321821
181511433	181511456	1	-	27260156	PANC0813	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.27715371491896623	[287]	[287,246,162,410]	-4	hSpCas9	negative selection	8321822
181511456	181511479	1	+	27260156	PANC0813	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.046011946626141165	[885]	[834,992,1360,836]	0	hSpCas9	negative selection	8386101
181577787	181577810	1	-	27260156	PANC0813	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.7558897700563684	[147]	[309,297,269,296]	9	hSpCas9	negative selection	8386102
181579107	181579130	1	+	27260156	PANC0813	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.2975221318735022	[1371]	[2159,1890,1786,2090]	5	hSpCas9	negative selection	8386103
181577784	181577807	1	+	27260156	RDES	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.16009792214831461	[599]	[525,437,759,797]	-3	hSpCas9	negative selection	8443071
181579203	181579226	1	+	27260156	RDES	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5248185803171191	[840]	[1061,1494,1366,1708]	8	hSpCas9	negative selection	8443072
181511433	181511456	1	-	27260156	RDES	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.18830203170024362	[287]	[209,281,302,393]	-3	hSpCas9	negative selection	8443073
181511456	181511479	1	+	27260156	RDES	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.060989803896217554	[885]	[728,1164,962,1068]	-1	hSpCas9	negative selection	8507352
181577787	181577810	1	-	27260156	RDES	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	0.904977962659271	[147]	[266,294,360,363]	9	hSpCas9	negative selection	8507353
181579107	181579130	1	+	27260156	RDES	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.48037993399703427	[1371]	[1821,1859,2552,2709]	7	hSpCas9	negative selection	8507354
181577784	181577807	1	+	27260156	PC3	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.10381022950942015	[599]	[287,575,1189,486]	-2	hSpCas9	negative selection	8564322
181579203	181579226	1	+	27260156	PC3	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.36115533296814395	[840]	[579,1205,2115,920]	7	hSpCas9	negative selection	8564323
181511433	181511456	1	-	27260156	PC3	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.2367271179082096	[287]	[237,242,484,462]	5	hSpCas9	negative selection	8564324
181511456	181511479	1	+	27260156	PC3	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.15400803718541356	[885]	[506,744,1215,926]	-3	hSpCas9	negative selection	8628603
181577787	181577810	1	-	27260156	PC3	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.1504006362385146	[147]	[180,251,530,471]	9	hSpCas9	negative selection	8628604
181579107	181579130	1	+	27260156	PC3	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.18999994247938767	[1371]	[1162,1548,2428,1427]	4	hSpCas9	negative selection	8628605
181577784	181577807	1	+	27260156	PATU8988T	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.2627784194798425	[599]	[396,885,940,561]	4	hSpCas9	negative selection	8685573
181579203	181579226	1	+	27260156	PATU8988T	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.3019465016594999	[840]	[906,1145,938,1031]	5	hSpCas9	negative selection	8685574
181511433	181511456	1	-	27260156	PATU8988T	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.43095302236552147	[287]	[430,420,222,436]	7	hSpCas9	negative selection	8685575
181511456	181511479	1	+	27260156	PATU8988T	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.05117093819958063	[885]	[691,686,1116,788]	-1	hSpCas9	negative selection	8749854
181577787	181577810	1	-	27260156	PATU8988T	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.2036803821900774	[147]	[299,325,358,331]	9	hSpCas9	negative selection	8749855
181579107	181579130	1	+	27260156	PATU8988T	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.3888029861686695	[1371]	[1414,1846,1496,2237]	6	hSpCas9	negative selection	8749856
181577784	181577807	1	+	27260156	T47D	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.07411110100672857	[599]	[837,565,736,819]	1	hSpCas9	negative selection	8806824
181579203	181579226	1	+	27260156	T47D	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.4015163529781206	[840]	[1354,1045,1373,1425]	8	hSpCas9	negative selection	8806825
181511433	181511456	1	-	27260156	T47D	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.03370312243204676	[287]	[315,216,447,337]	0	hSpCas9	negative selection	8806826
181511456	181511479	1	+	27260156	T47D	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.06328267379060903	[885]	[1024,878,855,1209]	-1	hSpCas9	negative selection	8871105
181577787	181577810	1	-	27260156	T47D	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.2628049908409948	[147]	[460,379,364,453]	9	hSpCas9	negative selection	8871106
181579107	181579130	1	+	27260156	T47D	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.35086476278531875	[1371]	[1884,1838,2056,2399]	7	hSpCas9	negative selection	8871107
181577784	181577807	1	+	27260156	SU8686	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.19601357205225212	[599]	[622,664,641,820]	3	hSpCas9	negative selection	8928075
181579203	181579226	1	+	27260156	SU8686	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5424641380589393	[840]	[1198,1026,1066,1647]	8	hSpCas9	negative selection	8928076
181511433	181511456	1	-	27260156	SU8686	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.04948774941857681	[287]	[306,236,338,305]	0	hSpCas9	negative selection	8928077
181511456	181511479	1	+	27260156	SU8686	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.10264741817092482	[885]	[740,673,916,992]	-2	hSpCas9	negative selection	8992356
181577787	181577810	1	-	27260156	SU8686	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.061888787954586	[147]	[358,303,280,265]	9	hSpCas9	negative selection	8992357
181579107	181579130	1	+	27260156	SU8686	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.269263527497259	[1371]	[1676,1195,1871,1902]	4	hSpCas9	negative selection	8992358
181577784	181577807	1	+	27260156	SKES1	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.1433056149053306	[599]	[833,663,623,552]	3	hSpCas9	negative selection	9049326
181579203	181579226	1	+	27260156	SKES1	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.20865581534671274	[840]	[973,994,956,947]	4	hSpCas9	negative selection	9049327
181511433	181511456	1	-	27260156	SKES1	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.20812159013039488	[287]	[375,257,397,292]	4	hSpCas9	negative selection	9049328
181511456	181511479	1	+	27260156	SKES1	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.14339510699497526	[885]	[940,897,738,662]	-3	hSpCas9	negative selection	9113607
181577787	181577810	1	-	27260156	SKES1	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.5268765210045836	[147]	[566,543,320,313]	9	hSpCas9	negative selection	9113608
181579107	181579130	1	+	27260156	SKES1	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.31982743336173547	[1371]	[2016,1738,1665,1468]	6	hSpCas9	negative selection	9113609
181577784	181577807	1	+	27260156	TOV112D	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.026422348866698142	[599]	[815,569,565,504]	0	hSpCas9	negative selection	9170577
181579203	181579226	1	+	27260156	TOV112D	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5416534482252385	[840]	[857,1588,1227,1283]	8	hSpCas9	negative selection	9170578
181511433	181511456	1	-	27260156	TOV112D	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.40468972715519486	[287]	[448,525,323,271]	7	hSpCas9	negative selection	9170579
181511456	181511479	1	+	27260156	TOV112D	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	0.0506605997719517	[885]	[1326,1071,616,735]	1	hSpCas9	negative selection	9234858
181577787	181577810	1	-	27260156	TOV112D	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.263993830258722	[147]	[342,464,317,323]	9	hSpCas9	negative selection	9234859
181579107	181579130	1	+	27260156	TOV112D	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.1444725185529141	[1371]	[1811,1544,1226,1519]	3	hSpCas9	negative selection	9234860
181577784	181577807	1	+	27260156	TC71	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	0.15810128264524026	[599]	[591,767,791,718]	4	hSpCas9	negative selection	9291828
181579203	181579226	1	+	27260156	TC71	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.3255541481784513	[840]	[1025,1201,1042,1260]	7	hSpCas9	negative selection	9291829
181511433	181511456	1	-	27260156	TC71	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	0.3066024737818763	[287]	[389,397,276,470]	7	hSpCas9	negative selection	9291830
181511456	181511479	1	+	27260156	TC71	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.20391776273770856	[885]	[862,923,706,805]	-5	hSpCas9	negative selection	9356109
181577787	181577810	1	-	27260156	TC71	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.37170012459249	[147]	[520,292,419,404]	9	hSpCas9	negative selection	9356110
181579107	181579130	1	+	27260156	TC71	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.23281794709801007	[1371]	[1718,1610,1781,1803]	6	hSpCas9	negative selection	9356111
181577784	181577807	1	+	27260156	TC32	viability	AACCCACTTCAATACTCACGTGG	CACNA1E	ENSG00000198216	-0.21143869440736232	[599]	[439,462,592,451]	-4	hSpCas9	negative selection	9413079
181579203	181579226	1	+	27260156	TC32	viability	GCATGCTTCATGAACAATTCAGG	CACNA1E	ENSG00000198216	0.5442343040450354	[840]	[1025,737,1755,1311]	8	hSpCas9	negative selection	9413080
181511433	181511456	1	-	27260156	TC32	viability	CCTTATGGAAGATGAACCCCAGG	CACNA1E	ENSG00000198216	-0.23235595234111617	[287]	[234,131,308,285]	-4	hSpCas9	negative selection	9413081
181511456	181511479	1	+	27260156	TC32	viability	GCTCTTACCTCCGCAATGGCTGG	CACNA1E	ENSG00000198216	-0.18254216414809443	[885]	[629,689,746,859]	-3	hSpCas9	negative selection	9477360
181577787	181577810	1	-	27260156	TC32	viability	GGTCCACGTGAGTATTGAAGTGG	CACNA1E	ENSG00000198216	1.2369844410313648	[147]	[284,310,478,248]	9	hSpCas9	negative selection	9477361
181579107	181579130	1	+	27260156	TC32	viability	ATGGTACCTCTTCTGCAGATTGG	CACNA1E	ENSG00000198216	0.5104057511223552	[1371]	[1546,1438,2411,2143]	8	hSpCas9	negative selection	9477362
181483791	181483814	1	+	27869803	HPAFII	viability after 27 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-0.8972383734233864	[237]	[34,93,NaN]	-6	hSpCas9	negative selection	9530859
181510566	181510589	1	-	27869803	HPAFII	viability after 27 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.7667347468442531	[404]	[340,379,NaN]	6	hSpCas9	negative selection	9530860
181511463	181511486	1	-	27869803	HPAFII	viability after 27 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.094825202993565	[516]	[256,317,NaN]	0	hSpCas9	negative selection	9530861
181577835	181577858	1	-	27869803	HPAFII	viability after 27 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-0.7516323721415037	[114]	[60,14,NaN]	-5	hSpCas9	negative selection	9530868
181580649	181580672	1	+	27869803	HPAFII	viability after 27 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.5414870111163358	[675]	[187,290,NaN]	-4	hSpCas9	negative selection	9530869
181651357	181651380	1	-	27869803	HPAFII	viability after 27 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.5357752613345768	[111]	[86,83,NaN]	4	hSpCas9	negative selection	9530870
181483791	181483814	1	+	27869803	HPAFII	viability after 15 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-0.7800854874094431	[237]	[172,133,NaN]	-7	hSpCas9	negative selection	9613308
181510566	181510589	1	-	27869803	HPAFII	viability after 15 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.8225682745399916	[404]	[836,727,NaN]	8	hSpCas9	negative selection	9613309
181511463	181511486	1	-	27869803	HPAFII	viability after 15 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.293660032400886	[516]	[493,427,NaN]	-3	hSpCas9	negative selection	9613310
181577835	181577858	1	-	27869803	HPAFII	viability after 15 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-0.1913235358046914	[114]	[217,39,NaN]	-2	hSpCas9	negative selection	9613317
181580649	181580672	1	+	27869803	HPAFII	viability after 15 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.3201010113309757	[675]	[761,469,NaN]	-4	hSpCas9	negative selection	9613318
181651357	181651380	1	-	27869803	HPAFII	viability after 15 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.6977516187195252	[111]	[230,172,NaN]	7	hSpCas9	negative selection	9613319
181483791	181483814	1	+	27869803	ASPC1	viability after 36 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	0.3520842742386594	[396]	[184,136,200]	3	hSpCas9	negative selection	9695757
181510566	181510589	1	-	27869803	ASPC1	viability after 36 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	-0.3003910236766393	[1291]	[590,288,265]	-3	hSpCas9	negative selection	9695758
181511463	181511486	1	-	27869803	ASPC1	viability after 36 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.10594841542778788	[1333]	[514,780,263]	1	hSpCas9	negative selection	9695759
181577835	181577858	1	-	27869803	ASPC1	viability after 36 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	0.6090078823097117	[320]	[264,102,156]	6	hSpCas9	negative selection	9695766
181580649	181580672	1	+	27869803	ASPC1	viability after 36 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.5227139907463643	[1223]	[756,1002,197]	5	hSpCas9	negative selection	9695767
181651357	181651380	1	-	27869803	ASPC1	viability after 36 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.21626155801641	[301]	[167,59,59]	-2	hSpCas9	negative selection	9695768
181483791	181483814	1	+	27869803	PATU8988S	viability after 35 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	0.8382803721472272	[264]	[112,268,NaN]	8	hSpCas9	negative selection	9778206
181510566	181510589	1	-	27869803	PATU8988S	viability after 35 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.8137236378683546	[1117]	[776,805,NaN]	8	hSpCas9	negative selection	9778207
181511463	181511486	1	-	27869803	PATU8988S	viability after 35 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.2959457904249422	[1224]	[562,239,NaN]	-3	hSpCas9	negative selection	9778208
181577835	181577858	1	-	27869803	PATU8988S	viability after 35 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	0.736447874239811	[163]	[129,89,NaN]	7	hSpCas9	negative selection	9778215
181580649	181580672	1	+	27869803	PATU8988S	viability after 35 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.48925502369749085	[1063]	[614,587,NaN]	5	hSpCas9	negative selection	9778216
181651357	181651380	1	-	27869803	PATU8988S	viability after 35 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.6017445963902207	[276]	[81,256,NaN]	6	hSpCas9	negative selection	9778217
181483791	181483814	1	+	27869803	PATU8988S	viability after 31 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	0.7111901387405465	[264]	[139,214,NaN]	8	hSpCas9	negative selection	9860655
181510566	181510589	1	-	27869803	PATU8988S	viability after 31 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.5186820636218383	[1117]	[573,720,NaN]	6	hSpCas9	negative selection	9860656
181511463	181511486	1	-	27869803	PATU8988S	viability after 31 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	-0.192161366212246	[1224]	[555,263,NaN]	-2	hSpCas9	negative selection	9860657
181577835	181577858	1	-	27869803	PATU8988S	viability after 31 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	0.22448442971122717	[163]	[93,53,NaN]	2	hSpCas9	negative selection	9860664
181580649	181580672	1	+	27869803	PATU8988S	viability after 31 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	0.29774270006042913	[1063]	[484,567,NaN]	3	hSpCas9	negative selection	9860665
181651357	181651380	1	-	27869803	PATU8988S	viability after 31 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.39896000748200444	[276]	[131,162,NaN]	5	hSpCas9	negative selection	9860666
181483791	181483814	1	+	27869803	HPAFII	viability after 35 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-0.9963658620824675	[237]	[26,97,NaN]	-5	hSpCas9	negative selection	9943104
181510566	181510589	1	-	27869803	HPAFII	viability after 35 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	1.0845920268505624	[404]	[431,437,NaN]	7	hSpCas9	negative selection	9943105
181511463	181511486	1	-	27869803	HPAFII	viability after 35 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.13380925863330906	[516]	[265,310,NaN]	0	hSpCas9	negative selection	9943106
181577835	181577858	1	-	27869803	HPAFII	viability after 35 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-1.1178367748552953	[114]	[31,20,NaN]	-6	hSpCas9	negative selection	9943113
181580649	181580672	1	+	27869803	HPAFII	viability after 35 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.0981463884401157	[675]	[219,431,NaN]	0	hSpCas9	negative selection	9943114
181651357	181651380	1	-	27869803	HPAFII	viability after 35 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.31803580799568665	[111]	[68,18,NaN]	-2	hSpCas9	negative selection	9943115
181483791	181483814	1	+	27869803	HPAFII	viability after 31 days	ATGGAGACTCGGACCAGAGCAGG	CACNA1E	ENSG00000198216	-1.566619544814664	[237]	[35,54,NaN]	-7	hSpCas9	negative selection	10025553
181510566	181510589	1	-	27869803	HPAFII	viability after 31 days	ACATACCAGTCTTCGGGACATGG	CACNA1E	ENSG00000198216	0.9471328392525138	[404]	[487,383,NaN]	7	hSpCas9	negative selection	10025554
181511463	181511486	1	-	27869803	HPAFII	viability after 31 days	TGACATTCCAGCCATTGCGGAGG	CACNA1E	ENSG00000198216	0.18019781353998798	[516]	[311,346,NaN]	1	hSpCas9	negative selection	10025555
181577835	181577858	1	-	27869803	HPAFII	viability after 31 days	ACACGAGCTTCAAAGGCCGCAGG	CACNA1E	ENSG00000198216	-1.3860969799516856	[114]	[28,19,NaN]	-7	hSpCas9	negative selection	10025562
181580649	181580672	1	+	27869803	HPAFII	viability after 31 days	CTGGTTATGAATGCAAGGACTGG	CACNA1E	ENSG00000198216	-0.10366278119160421	[675]	[298,411,NaN]	0	hSpCas9	negative selection	10025563
181651357	181651380	1	-	27869803	HPAFII	viability after 31 days	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.07056652435474442	[111]	[54,77,NaN]	0	hSpCas9	negative selection	10025564
181577817	181577840	1	-	28162770	P31FUJ	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-0.2592744157755698	[164]	[161]	-2	hSpCas9	negative selection	10124866
181785391	181785414	1	+	28162770	P31FUJ	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-1.6698660100232214	[175]	[64]	-8	hSpCas9	negative selection	10124867
181651357	181651380	1	-	28162770	P31FUJ	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.6151947021405715	[249]	[449]	7	hSpCas9	negative selection	10124868
181710989	181711012	1	+	28162770	P31FUJ	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.38078097424654545	[182]	[279]	4	hSpCas9	negative selection	10124869
181718123	181718146	1	-	28162770	P31FUJ	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	-0.3438335168031226	[134]	[124]	-3	hSpCas9	negative selection	10124870
181732468	181732491	1	+	28162770	P31FUJ	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.8692550203252771	[327]	[210]	-6	hSpCas9	negative selection	10124871
181732622	181732645	1	+	28162770	P31FUJ	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-0.11306296014028328	[103]	[112]	-1	hSpCas9	negative selection	10124872
181736372	181736395	1	+	28162770	P31FUJ	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.21857714192818561	[146]	[200]	2	hSpCas9	negative selection	10124873
181739200	181739223	1	+	28162770	P31FUJ	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.12532277572292827	[613]	[786]	1	hSpCas9	negative selection	10124874
181756944	181756967	1	+	28162770	P31FUJ	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-0.7744609209146744	[360]	[247]	-6	hSpCas9	negative selection	10124875
181577817	181577840	1	-	28162770	TF1	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10294232
181785391	181785414	1	+	28162770	TF1	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10294233
181651357	181651380	1	-	28162770	TF1	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[178]	1	hSpCas9	negative selection	10294234
181710989	181711012	1	+	28162770	TF1	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[145]	1	hSpCas9	negative selection	10294235
181718123	181718146	1	-	28162770	TF1	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10294236
181732468	181732491	1	+	28162770	TF1	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[157]	1	hSpCas9	negative selection	10294237
181732622	181732645	1	+	28162770	TF1	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[254]	1	hSpCas9	negative selection	10294238
181736372	181736395	1	+	28162770	TF1	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10294239
181739200	181739223	1	+	28162770	TF1	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[686]	1	hSpCas9	negative selection	10294240
181756944	181756967	1	+	28162770	TF1	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10294241
181577817	181577840	1	-	28162770	SKM1	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-0.9413006263943499	[62]	[57]	-6	hSpCas9	negative selection	10463598
181785391	181785414	1	+	28162770	SKM1	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	1.0423432026204282	[38]	[141]	8	hSpCas9	negative selection	10463599
181651357	181651380	1	-	28162770	SKM1	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.10740391688425371	[77]	[127]	-1	hSpCas9	negative selection	10463600
181710989	181711012	1	+	28162770	SKM1	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	-0.6391376408721949	[73]	[83]	-5	hSpCas9	negative selection	10463601
181718123	181718146	1	-	28162770	SKM1	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.5208860155010032	[40]	[103]	5	hSpCas9	negative selection	10463602
181732468	181732491	1	+	28162770	SKM1	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	0.18636177491262096	[85]	[172]	1	hSpCas9	negative selection	10463603
181732622	181732645	1	+	28162770	SKM1	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-1.0564669516590284	[39]	[33]	-6	hSpCas9	negative selection	10463604
181736372	181736395	1	+	28162770	SKM1	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	-1.8220016980220053	[51]	[25]	-8	hSpCas9	negative selection	10463605
181739200	181739223	1	+	28162770	SKM1	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	-0.20287259414965764	[152]	[234]	-2	hSpCas9	negative selection	10463606
181756944	181756967	1	+	28162770	SKM1	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-1.5272584324608736	[74]	[45]	-7	hSpCas9	negative selection	10463607
181577817	181577840	1	-	28162770	SKM1	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-0.9413006263943499	[62]	[57]	-6	hSpCas9	negative selection	10632964
181785391	181785414	1	+	28162770	SKM1	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	1.0423432026204282	[38]	[141]	8	hSpCas9	negative selection	10632965
181651357	181651380	1	-	28162770	SKM1	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.10740391688425371	[77]	[127]	-1	hSpCas9	negative selection	10632966
181710989	181711012	1	+	28162770	SKM1	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	-0.6391376408721949	[73]	[83]	-5	hSpCas9	negative selection	10632967
181718123	181718146	1	-	28162770	SKM1	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.5208860155010032	[40]	[103]	5	hSpCas9	negative selection	10632968
181732468	181732491	1	+	28162770	SKM1	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	0.18636177491262096	[85]	[172]	1	hSpCas9	negative selection	10632969
181732622	181732645	1	+	28162770	SKM1	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-1.0564669516590284	[39]	[33]	-6	hSpCas9	negative selection	10632970
181736372	181736395	1	+	28162770	SKM1	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	-1.8220016980220053	[51]	[25]	-8	hSpCas9	negative selection	10632971
181739200	181739223	1	+	28162770	SKM1	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	-0.20287259414965764	[152]	[234]	-2	hSpCas9	negative selection	10632972
181756944	181756967	1	+	28162770	SKM1	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-1.5272584324608736	[74]	[45]	-7	hSpCas9	negative selection	10632973
181577817	181577840	1	-	28162770	PL21	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-0.8222281985391345	[194]	[47]	-5	hSpCas9	negative selection	10802330
181785391	181785414	1	+	28162770	PL21	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-1.481684425484425	[153]	[23]	-7	hSpCas9	negative selection	10802331
181651357	181651380	1	-	28162770	PL21	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	-0.4867025002510496	[263]	[81]	-3	hSpCas9	negative selection	10802332
181710989	181711012	1	+	28162770	PL21	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	-0.8984884182383956	[226]	[52]	-6	hSpCas9	negative selection	10802333
181718123	181718146	1	-	28162770	PL21	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.28166949998591845	[171]	[90]	2	hSpCas9	negative selection	10802334
181732468	181732491	1	+	28162770	PL21	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	0.018104930769013095	[328]	[144]	0	hSpCas9	negative selection	10802335
181732622	181732645	1	+	28162770	PL21	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	0.8680635642258749	[106]	[84]	7	hSpCas9	negative selection	10802336
181736372	181736395	1	+	28162770	PL21	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	-1.0155890765661169	[143]	[30]	-6	hSpCas9	negative selection	10802337
181739200	181739223	1	+	28162770	PL21	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.5616138373527555	[438]	[281]	5	hSpCas9	negative selection	10802338
181756944	181756967	1	+	28162770	PL21	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-0.526484035455427	[277]	[83]	-4	hSpCas9	negative selection	10802339
181577817	181577840	1	-	28162770	P31FUJ	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-0.2592744157755698	[164]	[161]	-2	hSpCas9	negative selection	10971696
181785391	181785414	1	+	28162770	P31FUJ	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-1.6698660100232214	[175]	[64]	-8	hSpCas9	negative selection	10971697
181651357	181651380	1	-	28162770	P31FUJ	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.6151947021405715	[249]	[449]	7	hSpCas9	negative selection	10971698
181710989	181711012	1	+	28162770	P31FUJ	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.38078097424654545	[182]	[279]	4	hSpCas9	negative selection	10971699
181718123	181718146	1	-	28162770	P31FUJ	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	-0.3438335168031226	[134]	[124]	-3	hSpCas9	negative selection	10971700
181732468	181732491	1	+	28162770	P31FUJ	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.8692550203252771	[327]	[210]	-6	hSpCas9	negative selection	10971701
181732622	181732645	1	+	28162770	P31FUJ	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-0.11306296014028328	[103]	[112]	-1	hSpCas9	negative selection	10971702
181736372	181736395	1	+	28162770	P31FUJ	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.21857714192818561	[146]	[200]	2	hSpCas9	negative selection	10971703
181739200	181739223	1	+	28162770	P31FUJ	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.12532277572292827	[613]	[786]	1	hSpCas9	negative selection	10971704
181756944	181756967	1	+	28162770	P31FUJ	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-0.7744609209146744	[360]	[247]	-6	hSpCas9	negative selection	10971705
181577817	181577840	1	-	28162770	OCIAML5	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	0.599807696595218	[86]	[237]	5	hSpCas9	negative selection	11141062
181785391	181785414	1	+	28162770	OCIAML5	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-2.1870508185768056	[110]	[43]	-8	hSpCas9	negative selection	11141063
181651357	181651380	1	-	28162770	OCIAML5	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.3387977682706785	[151]	[346]	3	hSpCas9	negative selection	11141064
181710989	181711012	1	+	28162770	OCIAML5	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.5067268177752275	[84]	[217]	4	hSpCas9	negative selection	11141065
181718123	181718146	1	-	28162770	OCIAML5	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	-0.16556604368077876	[63]	[102]	-1	hSpCas9	negative selection	11141066
181732468	181732491	1	+	28162770	OCIAML5	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.5550848331068657	[174]	[214]	-4	hSpCas9	negative selection	11141067
181732622	181732645	1	+	28162770	OCIAML5	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-1.0391521234644923	[73]	[64]	-6	hSpCas9	negative selection	11141068
181736372	181736395	1	+	28162770	OCIAML5	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.2570551515161156	[69]	[150]	2	hSpCas9	negative selection	11141069
181739200	181739223	1	+	28162770	OCIAML5	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.25976747532475253	[365]	[790]	2	hSpCas9	negative selection	11141070
181756944	181756967	1	+	28162770	OCIAML5	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-1.4319580820377311	[141]	[94]	-7	hSpCas9	negative selection	11141071
181577817	181577840	1	-	28162770	EOL1	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	0.47263020659054394	[382]	[279]	4	hSpCas9	negative selection	11310428
181785391	181785414	1	+	28162770	EOL1	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-1.4601160786647902	[187]	[35]	-7	hSpCas9	negative selection	11310429
181651357	181651380	1	-	28162770	EOL1	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.27335157244929165	[467]	[297]	2	hSpCas9	negative selection	11310430
181710989	181711012	1	+	28162770	EOL1	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.1777790023739697	[442]	[263]	1	hSpCas9	negative selection	11310431
181718123	181718146	1	-	28162770	EOL1	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.6677723562084229	[275]	[230]	6	hSpCas9	negative selection	11310432
181732468	181732491	1	+	28162770	EOL1	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.23142578448918194	[565]	[253]	-2	hSpCas9	negative selection	11310433
181732622	181732645	1	+	28162770	EOL1	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	0.11497842844748818	[162]	[92]	1	hSpCas9	negative selection	11310434
181736372	181736395	1	+	28162770	EOL1	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	-0.6956041576129217	[165]	[53]	-5	hSpCas9	negative selection	11310435
181739200	181739223	1	+	28162770	EOL1	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.38761796727118003	[575]	[396]	3	hSpCas9	negative selection	11310436
181756944	181756967	1	+	28162770	EOL1	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-0.8138455268595292	[336]	[100]	-5	hSpCas9	negative selection	11310437
181577817	181577840	1	-	28162770	MOLM13	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-0.3138579274798972	[348]	[202]	-2	hSpCas9	negative selection	11479794
181785391	181785414	1	+	28162770	MOLM13	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-1.8896626230735047	[163]	[31]	-7	hSpCas9	negative selection	11479795
181651357	181651380	1	-	28162770	MOLM13	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.49019954326966725	[384]	[390]	3	hSpCas9	negative selection	11479796
181710989	181711012	1	+	28162770	MOLM13	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.41580087039612484	[281]	[271]	3	hSpCas9	negative selection	11479797
181718123	181718146	1	-	28162770	MOLM13	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.7182127356288188	[189]	[225]	5	hSpCas9	negative selection	11479798
181732468	181732491	1	+	28162770	MOLM13	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.7545030397918691	[398]	[170]	-4	hSpCas9	negative selection	11479799
181732622	181732645	1	+	28162770	MOLM13	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-1.375385114767968	[182]	[50]	-6	hSpCas9	negative selection	11479800
181736372	181736395	1	+	28162770	MOLM13	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.2481081736646688	[183]	[157]	1	hSpCas9	negative selection	11479801
181739200	181739223	1	+	28162770	MOLM13	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	-0.5264195063775654	[758]	[380]	-3	hSpCas9	negative selection	11479802
181756944	181756967	1	+	28162770	MOLM13	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-2.520037786154846	[356]	[44]	-8	hSpCas9	negative selection	11479803
181577817	181577840	1	-	28162770	HEL	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	0.2391969715593426	[249]	[188]	2	hSpCas9	negative selection	11649160
181785391	181785414	1	+	28162770	HEL	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-3.1273350739777874	[190]	[13]	-9	hSpCas9	negative selection	11649161
181651357	181651380	1	-	28162770	HEL	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	1.528935598571237	[322]	[596]	9	hSpCas9	negative selection	11649162
181710989	181711012	1	+	28162770	HEL	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.422094072950176	[274]	[235]	3	hSpCas9	negative selection	11649163
181718123	181718146	1	-	28162770	HEL	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.7587048500486819	[226]	[245]	6	hSpCas9	negative selection	11649164
181732468	181732491	1	+	28162770	HEL	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.820661688839886	[454]	[164]	-5	hSpCas9	negative selection	11649165
181732622	181732645	1	+	28162770	HEL	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-0.40718639333132534	[146]	[70]	-3	hSpCas9	negative selection	11649166
181736372	181736395	1	+	28162770	HEL	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.3404692628834629	[163]	[132]	3	hSpCas9	negative selection	11649167
181739200	181739223	1	+	28162770	HEL	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.43023198477434743	[605]	[522]	3	hSpCas9	negative selection	11649168
181756944	181756967	1	+	28162770	HEL	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-0.7141957127149186	[291]	[113]	-5	hSpCas9	negative selection	11649169
181577817	181577840	1	-	28162770	MV411	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-1.074490544104587	[179]	[71]	-6	hSpCas9	negative selection	11818526
181785391	181785414	1	+	28162770	MV411	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-1.1704149641031225	[170]	[63]	-6	hSpCas9	negative selection	11818527
181651357	181651380	1	-	28162770	MV411	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.2717874121985242	[234]	[238]	2	hSpCas9	negative selection	11818528
181710989	181711012	1	+	28162770	MV411	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	0.07424483550655198	[220]	[195]	0	hSpCas9	negative selection	11818529
181718123	181718146	1	-	28162770	MV411	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.05777633127920073	[137]	[120]	0	hSpCas9	negative selection	11818530
181732468	181732491	1	+	28162770	MV411	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.09734775239897464	[333]	[262]	0	hSpCas9	negative selection	11818531
181732622	181732645	1	+	28162770	MV411	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	0.1082748031111499	[86]	[78]	0	hSpCas9	negative selection	11818532
181736372	181736395	1	+	28162770	MV411	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.6829391526213349	[104]	[141]	6	hSpCas9	negative selection	11818533
181739200	181739223	1	+	28162770	MV411	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.4794586733170001	[383]	[450]	4	hSpCas9	negative selection	11818534
181756944	181756967	1	+	28162770	MV411	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-1.1222569630353143	[260]	[100]	-6	hSpCas9	negative selection	11818535
181577817	181577840	1	-	28162770	MONOMAC1	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	0.036022499328750346	[153]	[180]	0	hSpCas9	negative selection	11987892
181785391	181785414	1	+	28162770	MONOMAC1	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	0.041475239640171024	[88]	[104]	0	hSpCas9	negative selection	11987893
181651357	181651380	1	-	28162770	MONOMAC1	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.17168545930674972	[181]	[234]	1	hSpCas9	negative selection	11987894
181710989	181711012	1	+	28162770	MONOMAC1	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	-0.8392741531324589	[166]	[106]	-6	hSpCas9	negative selection	11987895
181718123	181718146	1	-	28162770	MONOMAC1	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.5323155629967773	[113]	[188]	5	hSpCas9	negative selection	11987896
181732468	181732491	1	+	28162770	MONOMAC1	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	0.0297340147874684	[187]	[219]	0	hSpCas9	negative selection	11987897
181732622	181732645	1	+	28162770	MONOMAC1	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-0.2543700221255052	[76]	[73]	-2	hSpCas9	negative selection	11987898
181736372	181736395	1	+	28162770	MONOMAC1	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	-0.8003778770955646	[78]	[51]	-6	hSpCas9	negative selection	11987899
181739200	181739223	1	+	28162770	MONOMAC1	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	-0.172707517697813	[293]	[298]	-1	hSpCas9	negative selection	11987900
181756944	181756967	1	+	28162770	MONOMAC1	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	0.4600754394174379	[155]	[245]	4	hSpCas9	negative selection	11987901
181577817	181577840	1	-	28162770	OCIAML2	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	0.1687804595013713	[38]	[242]	1	hSpCas9	negative selection	12157258
181785391	181785414	1	+	28162770	OCIAML2	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-2.29005757960034	[29]	[33]	-8	hSpCas9	negative selection	12157259
181651357	181651380	1	-	28162770	OCIAML2	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.2949049211208158	[49]	[339]	3	hSpCas9	negative selection	12157260
181710989	181711012	1	+	28162770	OCIAML2	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	-0.5505981299455762	[50]	[192]	-4	hSpCas9	negative selection	12157261
181718123	181718146	1	-	28162770	OCIAML2	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	0.009802092007688334	[30]	[172]	0	hSpCas9	negative selection	12157262
181732468	181732491	1	+	28162770	OCIAML2	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	-0.5824206506997178	[56]	[210]	-4	hSpCas9	negative selection	12157263
181732622	181732645	1	+	28162770	OCIAML2	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-0.7206080782505087	[21]	[73]	-5	hSpCas9	negative selection	12157264
181736372	181736395	1	+	28162770	OCIAML2	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	0.0392312202382763	[22]	[130]	0	hSpCas9	negative selection	12157265
181739200	181739223	1	+	28162770	OCIAML2	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.35403764505868396	[70]	[502]	3	hSpCas9	negative selection	12157266
181756944	181756967	1	+	28162770	OCIAML2	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-0.07009189565843249	[24]	[131]	0	hSpCas9	negative selection	12157267
181577817	181577840	1	-	28162770	OCIAML3	viability	GCAGGACACGCACAGCCCGGAGG	CACNA1E	ENSG00000198216	-0.734870176164013	[42]	[77]	-5	hSpCas9	negative selection	12326624
181785391	181785414	1	+	28162770	OCIAML3	viability	GAAGCAGAGGCAGCAGCTGGAGG	CACNA1E	ENSG00000198216	-1.066076084639386	[42]	[61]	-6	hSpCas9	negative selection	12326625
181651357	181651380	1	-	28162770	OCIAML3	viability	GAAGTACAGCCAATTCCAGGTGG	CACNA1E	ENSG00000198216	0.49214900342555146	[64]	[275]	4	hSpCas9	negative selection	12326626
181710989	181711012	1	+	28162770	OCIAML3	viability	GAAGGGCTTTCATGAAGCTGCGG	CACNA1E	ENSG00000198216	-0.2032176872919966	[44]	[117]	-1	hSpCas9	negative selection	12326627
181718123	181718146	1	-	28162770	OCIAML3	viability	GAAGAGTGAAAATAAAGGCGAGG	CACNA1E	ENSG00000198216	-0.9067950813550565	[58]	[94]	-6	hSpCas9	negative selection	12326628
181732468	181732491	1	+	28162770	OCIAML3	viability	GGAGGCCCTCAACAGAGAGGAGG	CACNA1E	ENSG00000198216	0.005676366103758601	[64]	[196]	0	hSpCas9	negative selection	12326629
181732622	181732645	1	+	28162770	OCIAML3	viability	GAGGAGGAGCGCATCAGCCGTGG	CACNA1E	ENSG00000198216	-0.49212802630494956	[40]	[87]	-4	hSpCas9	negative selection	12326630
181736372	181736395	1	+	28162770	OCIAML3	viability	GCGTGAGACAGGCAAAGCCATGG	CACNA1E	ENSG00000198216	1.467103873979224	[25]	[216]	9	hSpCas9	negative selection	12326631
181739200	181739223	1	+	28162770	OCIAML3	viability	GAACATCCTGGACTTTGTGGTGG	CACNA1E	ENSG00000198216	0.3811889686752643	[131]	[518]	3	hSpCas9	negative selection	12326632
181756944	181756967	1	+	28162770	OCIAML3	viability	GATGTGACAGAGGAAGACCGAGG	CACNA1E	ENSG00000198216	-1.120938019673904	[66]	[92]	-7	hSpCas9	negative selection	12326633