Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10203
• Symbol:CALCRL
• Description:calcitonin receptor like receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/CALCRL

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
187380466	187380489	2	-	26472758	Jiyoye	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	3.063522515463795	[22]	[144]	9	hSpCas9	negative selection	22799
187380479	187380502	2	+	26472758	Jiyoye	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.24453770268984854	[468]	[418]	1	hSpCas9	negative selection	22800
187363378	187363401	2	+	26472758	Jiyoye	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	1.277540101089278	[63]	[116]	7	hSpCas9	negative selection	22801
187360649	187360672	2	-	26472758	Jiyoye	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	0.4637589098722408	[74]	[77]	3	hSpCas9	negative selection	22802
187359068	187359091	2	+	26472758	Jiyoye	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.8677275400370859	[116]	[160]	6	hSpCas9	negative selection	22803
187383269	187383292	2	-	26472758	Jiyoye	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.1798674697553091	[342]	[292]	1	hSpCas9	negative selection	22804
187383172	187383195	2	-	26472758	Jiyoye	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	-0.69591811145823	[57]	[26]	-5	hSpCas9	negative selection	22805
187363408	187363431	2	-	26472758	Jiyoye	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	-0.7113390897535168	[316]	[145]	-5	hSpCas9	negative selection	22806
187352155	187352178	2	-	26472758	Jiyoye	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.6317356395250315	[94]	[110]	4	hSpCas9	negative selection	22807
187359245	187359268	2	+	26472758	Jiyoye	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	-0.7739943771040616	[160]	[70]	-5	hSpCas9	negative selection	22808
187380466	187380489	2	-	26472758	KBM7	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.9710557181474422	[289,300]	[326,226]	9	hSpCas9	negative selection	213917
187380479	187380502	2	+	26472758	KBM7	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.8161669539351388	[1750,1887]	[1246,1762]	8	hSpCas9	negative selection	213918
187363378	187363401	2	+	26472758	KBM7	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.38867419688952365	[292,198]	[116,177]	4	hSpCas9	negative selection	213919
187360649	187360672	2	-	26472758	KBM7	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	-0.004003478727398813	[214,207]	[146,56]	0	hSpCas9	negative selection	213920
187359068	187359091	2	+	26472758	KBM7	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.6001140562272295	[576,503]	[394,374]	6	hSpCas9	negative selection	213921
187383269	187383292	2	-	26472758	KBM7	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.4717140345683357	[1251,924]	[913,512]	5	hSpCas9	negative selection	213922
187383172	187383195	2	-	26472758	KBM7	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.375586255795639	[253,243]	[117,182]	4	hSpCas9	negative selection	213923
187363408	187363431	2	-	26472758	KBM7	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	-0.19330667376706845	[969,1038]	[396,433]	-2	hSpCas9	negative selection	213924
187352155	187352178	2	-	26472758	KBM7	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.43592156363005125	[702,574]	[238,551]	5	hSpCas9	negative selection	213925
187359245	187359268	2	+	26472758	KBM7	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	0.3971167745993936	[429,450]	[307,244]	4	hSpCas9	negative selection	213926
187380466	187380489	2	-	26472758	Raji	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.003046875558863904	[171]	[39]	0	hSpCas9	negative selection	405035
187380479	187380502	2	+	26472758	Raji	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.6433085427862009	[777]	[281]	6	hSpCas9	negative selection	405036
187363378	187363401	2	+	26472758	Raji	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.7699339448515721	[168]	[22]	-5	hSpCas9	negative selection	405037
187360649	187360672	2	-	26472758	Raji	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	1.4021268009347312	[74]	[45]	9	hSpCas9	negative selection	405038
187359068	187359091	2	+	26472758	Raji	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.9287413168301781	[248]	[109]	8	hSpCas9	negative selection	405039
187383269	187383292	2	-	26472758	Raji	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	1.0234317570411402	[512]	[241]	8	hSpCas9	negative selection	405040
187383172	187383195	2	-	26472758	Raji	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.3815584988125936	[171]	[51]	3	hSpCas9	negative selection	405041
187363408	187363431	2	-	26472758	Raji	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.40324933367476556	[390]	[119]	4	hSpCas9	negative selection	405042
187352155	187352178	2	-	26472758	Raji	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.34636191586383014	[382]	[112]	3	hSpCas9	negative selection	405043
187359245	187359268	2	+	26472758	Raji	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	0.573404963371248	[138]	[47]	5	hSpCas9	negative selection	405044
187380466	187380489	2	-	26472758	K562	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	1.1813400450430667	[186]	[357]	8	hSpCas9	negative selection	596153
187380479	187380502	2	+	26472758	K562	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.30801888989520565	[1419]	[1483]	2	hSpCas9	negative selection	596154
187363378	187363401	2	+	26472758	K562	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.6741030029096922	[195]	[263]	5	hSpCas9	negative selection	596155
187360649	187360672	2	-	26472758	K562	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	-0.22124484468236538	[86]	[62]	-1	hSpCas9	negative selection	596156
187359068	187359091	2	+	26472758	K562	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.8451688437378454	[514]	[780]	7	hSpCas9	negative selection	596157
187383269	187383292	2	-	26472758	K562	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.3523185383714842	[836]	[901]	2	hSpCas9	negative selection	596158
187383172	187383195	2	-	26472758	K562	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.44051440529466745	[260]	[298]	3	hSpCas9	negative selection	596159
187363408	187363431	2	-	26472758	K562	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.24062714850407274	[761]	[759]	1	hSpCas9	negative selection	596160
187352155	187352178	2	-	26472758	K562	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.7072768639520497	[496]	[684]	6	hSpCas9	negative selection	596161
187359245	187359268	2	+	26472758	K562	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	0.24858235260798323	[345]	[346]	2	hSpCas9	negative selection	596162
187346260	187346283	2	+	26627737	DLD1	viability	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.47544535499021845	[351]	[248,136,82]	5	hSpCas9	negative selection	809606
187352163	187352186	2	+	26627737	DLD1	viability	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.13812303360324396	[167]	[13,101,31]	-1	hSpCas9	negative selection	809607
187363378	187363401	2	+	26627737	DLD1	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.32066371567236396	[98]	[16,78,23]	3	hSpCas9	negative selection	809608
187363396	187363419	2	-	26627737	DLD1	viability	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.0883289104649485	[1095]	[407,523,193]	0	hSpCas9	negative selection	809609
187380730	187380753	2	-	26627737	DLD1	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.6102714483290909	[425]	[116,94,54]	-5	hSpCas9	negative selection	809610
187346260	187346283	2	+	26627737	GBM cells	viability after 5 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.5216312976022599	[175]	[172,97]	7	hSpCas9	negative selection	891921
187352163	187352186	2	+	26627737	GBM cells	viability after 5 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.8254516825008869	[113]	[32,35]	-8	hSpCas9	negative selection	891922
187363378	187363401	2	+	26627737	GBM cells	viability after 5 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	1.0244447569695447	[21]	[22,24]	9	hSpCas9	negative selection	891923
187363396	187363419	2	-	26627737	GBM cells	viability after 5 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.004915228742573996	[563]	[294,311]	0	hSpCas9	negative selection	891924
187380730	187380753	2	-	26627737	GBM cells	viability after 5 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.11565892620158691	[198]	[99,96]	-2	hSpCas9	negative selection	891925
187346260	187346283	2	+	26627737	GBM cells	viability after 13 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.6796432856148003	[175]	[206,108]	8	hSpCas9	negative selection	974236
187352163	187352186	2	+	26627737	GBM cells	viability after 13 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.28879926626671804	[113]	[75,29]	-3	hSpCas9	negative selection	974237
187363378	187363401	2	+	26627737	GBM cells	viability after 13 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	1.0605749215864528	[21]	[25,23]	9	hSpCas9	negative selection	974238
187363396	187363419	2	-	26627737	GBM cells	viability after 13 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.029279387508469368	[563]	[335,292]	0	hSpCas9	negative selection	974239
187380730	187380753	2	-	26627737	GBM cells	viability after 13 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.7304198354417355	[198]	[182,175]	8	hSpCas9	negative selection	974240
187346260	187346283	2	+	26627737	GBM cells	viability after 21 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.3914508572459505	[175]	[138,112]	4	hSpCas9	negative selection	1056551
187352163	187352186	2	+	26627737	GBM cells	viability after 21 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-1.6788093232276569	[113]	[22,15]	-8	hSpCas9	negative selection	1056552
187363378	187363401	2	+	26627737	GBM cells	viability after 21 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	1.6504750486561632	[21]	[36,37]	9	hSpCas9	negative selection	1056553
187363396	187363419	2	-	26627737	GBM cells	viability after 21 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.6744381628262583	[563]	[511,467]	6	hSpCas9	negative selection	1056554
187380730	187380753	2	-	26627737	GBM cells	viability after 21 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.33660067186294723	[198]	[135,136]	3	hSpCas9	negative selection	1056555
187346260	187346283	2	+	26627737	RPE1	viability after 9 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	-0.12049161949040162	[865]	[258,236]	-1	hSpCas9	negative selection	1138866
187352163	187352186	2	+	26627737	RPE1	viability after 9 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.9598099352309244	[289]	[128,237]	6	hSpCas9	negative selection	1138867
187363378	187363401	2	+	26627737	RPE1	viability after 9 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.6790279017217551	[84]	[1,94]	4	hSpCas9	negative selection	1138868
187363396	187363419	2	-	26627737	RPE1	viability after 9 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.12004688415581688	[1876]	[573,721]	0	hSpCas9	negative selection	1138869
187380730	187380753	2	-	26627737	RPE1	viability after 9 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	4.170794884207182	[63]	[328,401]	9	hSpCas9	negative selection	1138870
187346260	187346283	2	+	26627737	RPE1	viability after 12 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	-0.0018229214396856541	[865]	[210,254]	0	hSpCas9	negative selection	1221181
187352163	187352186	2	+	26627737	RPE1	viability after 12 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	1.0822746969492187	[289]	[180,147]	6	hSpCas9	negative selection	1221182
187363378	187363401	2	+	26627737	RPE1	viability after 12 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.7378985236794424	[84]	[6,70]	5	hSpCas9	negative selection	1221183
187363396	187363419	2	-	26627737	RPE1	viability after 12 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	-0.3258199128583765	[1876]	[311,497]	-2	hSpCas9	negative selection	1221184
187380730	187380753	2	-	26627737	RPE1	viability after 12 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	4.520045143907127	[63]	[496,285]	9	hSpCas9	negative selection	1221185
187346260	187346283	2	+	26627737	RPE1	viability after 15 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	-0.11583329090207685	[865]	[221,229]	0	hSpCas9	negative selection	1303496
187352163	187352186	2	+	26627737	RPE1	viability after 15 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.6963366783942389	[289]	[136,128]	4	hSpCas9	negative selection	1303497
187363378	187363401	2	+	26627737	RPE1	viability after 15 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.10583350051445706	[84]	[2,40]	0	hSpCas9	negative selection	1303498
187363396	187363419	2	-	26627737	RPE1	viability after 15 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	-0.38831042695088125	[1876]	[339,468]	-2	hSpCas9	negative selection	1303499
187380730	187380753	2	-	26627737	RPE1	viability after 15 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	3.9551875203081726	[63]	[375,188]	9	hSpCas9	negative selection	1303500
187346260	187346283	2	+	26627737	RPE1	viability after 18 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	-0.3490863866099756	[865]	[211,152]	-2	hSpCas9	negative selection	1385811
187352163	187352186	2	+	26627737	RPE1	viability after 18 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.8261893664410453	[289]	[189,83]	5	hSpCas9	negative selection	1385812
187363378	187363401	2	+	26627737	RPE1	viability after 18 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	1.0956846950661099	[84]	[5,94]	6	hSpCas9	negative selection	1385813
187363396	187363419	2	-	26627737	RPE1	viability after 18 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	-0.26415856828638695	[1876]	[269,583]	-2	hSpCas9	negative selection	1385814
187380730	187380753	2	-	26627737	RPE1	viability after 18 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	4.3310390790172715	[63]	[423,265]	9	hSpCas9	negative selection	1385815
187346260	187346283	2	+	26627737	HeLa	viability after 8 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	1.3056097309205401	[161]	[215,201,117]	8	hSpCas9	negative selection	1468126
187352163	187352186	2	+	26627737	HeLa	viability after 8 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.43870587912904735	[252]	[17,148,63]	-4	hSpCas9	negative selection	1468127
187363378	187363401	2	+	26627737	HeLa	viability after 8 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	1.9297263382631338	[45]	[148,81,17]	9	hSpCas9	negative selection	1468128
187363396	187363419	2	-	26627737	HeLa	viability after 8 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.008286988376319693	[877]	[398,283,466]	0	hSpCas9	negative selection	1468129
187380730	187380753	2	-	26627737	HeLa	viability after 8 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.8601346885440713	[299]	[275,169,270]	7	hSpCas9	negative selection	1468130
187346260	187346283	2	+	26627737	HeLa	viability after 12 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	1.3587740048159347	[161]	[200,142,174]	8	hSpCas9	negative selection	1550441
187352163	187352186	2	+	26627737	HeLa	viability after 12 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.20787977830313664	[252]	[132,50,92]	-2	hSpCas9	negative selection	1550442
187363378	187363401	2	+	26627737	HeLa	viability after 12 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	1.6697712844146964	[45]	[111,59,10]	9	hSpCas9	negative selection	1550443
187363396	187363419	2	-	26627737	HeLa	viability after 12 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.22513117648329262	[877]	[565,258,468]	2	hSpCas9	negative selection	1550444
187380730	187380753	2	-	26627737	HeLa	viability after 12 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	1.183000887162942	[299]	[186,278,375]	8	hSpCas9	negative selection	1550445
187346260	187346283	2	+	26627737	HeLa	viability after 15 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	1.047198660168403	[161]	[165,111,129]	7	hSpCas9	negative selection	1632756
187352163	187352186	2	+	26627737	HeLa	viability after 15 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.6544641334463903	[252]	[59,309,113]	5	hSpCas9	negative selection	1632757
187363378	187363401	2	+	26627737	HeLa	viability after 15 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.4047017099753951	[45]	[1,67,2]	3	hSpCas9	negative selection	1632758
187363396	187363419	2	-	26627737	HeLa	viability after 15 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.2677695114642975	[877]	[304,600,382]	2	hSpCas9	negative selection	1632759
187380730	187380753	2	-	26627737	HeLa	viability after 15 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.6592562837865839	[299]	[176,206,194]	5	hSpCas9	negative selection	1632760
187346260	187346283	2	+	26627737	HeLa	viability after 18 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	1.0375244552310203	[161]	[110,90,129]	7	hSpCas9	negative selection	1715071
187352163	187352186	2	+	26627737	HeLa	viability after 18 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.6780219119076062	[252]	[37,265,113]	5	hSpCas9	negative selection	1715072
187363378	187363401	2	+	26627737	HeLa	viability after 18 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.5742477437161138	[45]	[1,62,2]	4	hSpCas9	negative selection	1715073
187363396	187363419	2	-	26627737	HeLa	viability after 18 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.3116318732303418	[877]	[226,501,382]	2	hSpCas9	negative selection	1715074
187380730	187380753	2	-	26627737	HeLa	viability after 18 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.6681412634960202	[299]	[118,173,194]	5	hSpCas9	negative selection	1715075
187346260	187346283	2	+	26627737	HCT116	viability after 6 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.021517445831789828	[398]	[53,68]	0	hSpCas9	negative selection	1797386
187352163	187352186	2	+	26627737	HCT116	viability after 6 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.02318247289655151	[80]	[27,3]	0	hSpCas9	negative selection	1797387
187363378	187363401	2	+	26627737	HCT116	viability after 6 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.023159855513057326	[385]	[31,74]	0	hSpCas9	negative selection	1797388
187363396	187363419	2	-	26627737	HCT116	viability after 6 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.03906199795959142	[1318]	[330,147]	0	hSpCas9	negative selection	1797389
187380730	187380753	2	-	26627737	HCT116	viability after 6 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.4495216325826631	[688]	[261,84]	2	hSpCas9	negative selection	1797390
187346260	187346283	2	+	26627737	HCT116	viability after 8 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	2.586652964416763	[46]	[53,180,228]	9	hSpCas9	negative selection	1879701
187352163	187352186	2	+	26627737	HCT116	viability after 8 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.45951697916017586	[207]	[93,52,102]	-5	hSpCas9	negative selection	1879702
187363378	187363401	2	+	26627737	HCT116	viability after 8 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.19685455424232723	[90]	[41,27,60]	-2	hSpCas9	negative selection	1879703
187363396	187363419	2	-	26627737	HCT116	viability after 8 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.31082053210706717	[684]	[483,462,457]	3	hSpCas9	negative selection	1879704
187380730	187380753	2	-	26627737	HCT116	viability after 8 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.7589396268959734	[179]	[126,223,151]	7	hSpCas9	negative selection	1879705
187346260	187346283	2	+	26627737	HCT116	viability after 9 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.006090386767672262	[398]	[87,121]	0	hSpCas9	negative selection	1962016
187352163	187352186	2	+	26627737	HCT116	viability after 9 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.8293921924593093	[80]	[81,3]	6	hSpCas9	negative selection	1962017
187363378	187363401	2	+	26627737	HCT116	viability after 9 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.22989141270063151	[385]	[40,183]	1	hSpCas9	negative selection	1962018
187363396	187363419	2	-	26627737	HCT116	viability after 9 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.9517490097256647	[1318]	[535,795]	6	hSpCas9	negative selection	1962019
187380730	187380753	2	-	26627737	HCT116	viability after 9 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.3076372439768106	[688]	[220,232]	2	hSpCas9	negative selection	1962020
187346260	187346283	2	+	26627737	HCT116	viability after 12 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	2.8593997161373887	[46]	[103,246,194]	9	hSpCas9	negative selection	2044331
187352163	187352186	2	+	26627737	HCT116	viability after 12 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.5993190559601924	[207]	[66,75,73]	-6	hSpCas9	negative selection	2044332
187363378	187363401	2	+	26627737	HCT116	viability after 12 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.772776094253588	[90]	[15,26,41]	-7	hSpCas9	negative selection	2044333
187363396	187363419	2	-	26627737	HCT116	viability after 12 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.27320967270677476	[684]	[390,517,401]	3	hSpCas9	negative selection	2044334
187380730	187380753	2	-	26627737	HCT116	viability after 12 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	1.3945502636012161	[179]	[289,105,342]	9	hSpCas9	negative selection	2044335
187346260	187346283	2	+	26627737	HCT116	viability after 15 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	2.5718362966987387	[46]	[149,154,174]	9	hSpCas9	negative selection	2126646
187352163	187352186	2	+	26627737	HCT116	viability after 15 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.15947230827280012	[207]	[100,136,157]	1	hSpCas9	negative selection	2126647
187363378	187363401	2	+	26627737	HCT116	viability after 15 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.15798153361984957	[90]	[65,62,46]	1	hSpCas9	negative selection	2126648
187363396	187363419	2	-	26627737	HCT116	viability after 15 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.3870744344468273	[684]	[587,672,293]	4	hSpCas9	negative selection	2126649
187380730	187380753	2	-	26627737	HCT116	viability after 15 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.953180740229594	[179]	[209,138,251]	7	hSpCas9	negative selection	2126650
187346260	187346283	2	+	26627737	HCT116	viability after 18 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	2.055867660702504	[46]	[81,128,68]	9	hSpCas9	negative selection	2208961
187352163	187352186	2	+	26627737	HCT116	viability after 18 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.7774406272907917	[207]	[30,69,74]	-6	hSpCas9	negative selection	2208962
187363378	187363401	2	+	26627737	HCT116	viability after 18 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.47942536274738545	[90]	[42,23,27]	-4	hSpCas9	negative selection	2208963
187363396	187363419	2	-	26627737	HCT116	viability after 18 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.9359616363302341	[684]	[864,715,298]	7	hSpCas9	negative selection	2208964
187380730	187380753	2	-	26627737	HCT116	viability after 18 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	1.4836249233706535	[179]	[241,175,319]	9	hSpCas9	negative selection	2208965
187448383	187448406	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGAAAGGAGTGCTGCTTTCCTGG	CALCRL	ENSG00000064989	0.0021614313444513478	[45,52]	[2,18]	0	dCas9-VP64	positive selection	2438614
187448432	187448455	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTGAACAGAGAGAGATCATAGG	CALCRL	ENSG00000064989	-0.6955611213095998	[320,163]	[40,22]	-4	dCas9-VP64	positive selection	2438616
187448383	187448406	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGAAAGGAGTGCTGCTTTCCTGG	CALCRL	ENSG00000064989	0.20391588160851803	[82,67]	[19,34]	1	dCas9-VP64	positive selection	2533869
187448432	187448455	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTGAACAGAGAGAGATCATAGG	CALCRL	ENSG00000064989	-0.04833747033411184	[190,193]	[63,56]	0	dCas9-VP64	positive selection	2533871
187380462	187380485	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATACCTTCACTTTCTCGTGGG	CALCRL	ENSG00000064989	0.18602382387942928	[6,6]	[6,6]	4	hSpCas9	positive selection	2976037
187383269	187383292	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-0.023383003928884663	[3,3]	[3,1]	0	hSpCas9	positive selection	2976038
187380764	187380787	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	-1.0048369541707396	[3,3]	[1,0]	-9	hSpCas9	positive selection	2976039
187363484	187363507	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-0.17640470522125035	[3,4]	[3,2]	-3	hSpCas9	positive selection	2976040
187380462	187380485	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATACCTTCACTTTCTCGTGGG	CALCRL	ENSG00000064989	0.012795833016853497	[6,6]	[5,3]	0	hSpCas9	positive selection	3043895
187383269	187383292	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-0.14921200849360075	[3,3]	[3,0]	-2	hSpCas9	positive selection	3043896
187380764	187380787	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	-0.06424813078141596	[3,3]	[3,1]	-1	hSpCas9	positive selection	3043897
187363484	187363507	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-0.27111073767704597	[3,3]	[3,0]	-4	hSpCas9	positive selection	3043898
187380460	187380483		+	24336571	A375	resistance to PLX after 7 days	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.22248540344416523	[20,22]	[23,26]	6	hSpCas9	positive selection	3160334
187380466	187380489		-	24336571	A375	resistance to PLX after 7 days	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.6585516084126988	[3,4]	[7,6]	9	hSpCas9	positive selection	3160335
187380730	187380753		-	24336571	A375	resistance to PLX after 7 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.20310116345359192	[12,9]	[9,9]	-6	hSpCas9	positive selection	3160336
187380460	187380483		+	24336571	A375	resistance to PLX after 14 days	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	-0.9640678524489172	[21,28]	[5,4]	-9	hSpCas9	positive selection	3218127
187380466	187380489		-	24336571	A375	resistance to PLX after 14 days	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.7027967044786141	[3,1]	[1,1]	6	hSpCas9	positive selection	3218128
187380730	187380753		-	24336571	A375	resistance to PLX after 14 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.5431494584046382	[13,12]	[4,3]	-6	hSpCas9	positive selection	3218129
187380460	187380483		+	24336571	A375	viability after 7 days	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	-0.12891627865873645	[24]	[20,22]	-2	hSpCas9	negative selection	3275920
187380466	187380489		-	24336571	A375	viability after 7 days	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.6128882275412632	[7]	[3,4]	-7	hSpCas9	negative selection	3275921
187380730	187380753		-	24336571	A375	viability after 7 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.39267213938000267	[8]	[12,9]	6	hSpCas9	negative selection	3275922
187380460	187380483		+	24336571	A375	viability after 14 days	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.09369806292929761	[24]	[21,28]	1	hSpCas9	negative selection	3333713
187380466	187380489		-	24336571	A375	viability after 14 days	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-1.1228591298482566	[7]	[3,1]	-8	hSpCas9	negative selection	3333714
187380730	187380753		-	24336571	A375	viability after 14 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.6444664833790734	[8]	[13,12]	7	hSpCas9	negative selection	3333715
187380730	187380753	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.7086466484783841	[254,244]	[0,0]	-5	hSpCas9	positive selection	3340841
187363373	187363396	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	-0.26864232772931507	[154,213]	[0,0]	-2	hSpCas9	positive selection	3340842
187380460	187380483	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.16660836236189885	[106,165]	[0,0]	0	hSpCas9	positive selection	3340843
187380765	187380788	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.35000410230377543	[194,194]	[0,0]	-2	hSpCas9	positive selection	3360090
187380466	187380489	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.04787284581688529	[147,147]	[0,0]	0	hSpCas9	positive selection	3360091
187363484	187363507	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-1.2345268848838393	[359,359]	[0,0]	-7	hSpCas9	positive selection	3360092
187380461	187380484	2	+	26780180	HT29	viability (Avana library 4 designs)	ACATACCTTCACTTTCTCGTGGG	CALCRL	ENSG00000064989	0.376068536342688	[]	[]	1	hSpCas9	negative selection	3412314
187383269	187383292	2	-	26780180	HT29	viability (Avana library 4 designs)	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	1.17555576282695	[]	[]	4	hSpCas9	negative selection	3412315
187380764	187380787	2	-	26780180	HT29	viability (Avana library 4 designs)	CGTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.848446183821035	[]	[]	3	hSpCas9	negative selection	3412316
187363484	187363507	2	-	26780180	HT29	viability (Avana library 4 designs)	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-0.139262990963729	[]	[]	-2	hSpCas9	negative selection	3412317
187380764	187380787	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.831041006850598	[]	[]	1	hSpCas9	negative selection	3487716
187363484	187363507	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.097365597496303	[]	[]	0	hSpCas9	negative selection	3487717
187380461	187380484	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACATACCTTCACTTTCTCGTGGG	CALCRL	ENSG00000064989	-3.05677423658617	[]	[]	-4	hSpCas9	negative selection	3487718
187383269	187383292	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-1.31431939363368	[]	[]	-2	hSpCas9	negative selection	3487719
187383253	187383276	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGAGGACTCAATTCAGTTGGG	CALCRL	ENSG00000064989	3.06294144313537	[]	[]	5	hSpCas9	negative selection	3487720
187378991	187379014	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	-1.09991805972285	[]	[]	-1	hSpCas9	negative selection	3487721
187380764	187380787	2	-	26780180	A375	viability (Avana lentiGuide)	CGTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	1.17833611517987	[]	[]	1	hSpCas9	negative selection	3596375
187363484	187363507	2	-	26780180	A375	viability (Avana lentiGuide)	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-2.85409470868045	[]	[]	-5	hSpCas9	negative selection	3596376
187380461	187380484	2	+	26780180	A375	viability (Avana lentiGuide)	ACATACCTTCACTTTCTCGTGGG	CALCRL	ENSG00000064989	1.24466544280183	[]	[]	1	hSpCas9	negative selection	3596377
187383269	187383292	2	-	26780180	A375	viability (Avana lentiGuide)	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-4.64244777552957	[]	[]	-7	hSpCas9	negative selection	3596378
187383253	187383276	2	-	26780180	A375	viability (Avana lentiGuide)	CCTGAGGACTCAATTCAGTTGGG	CALCRL	ENSG00000064989	-2.81395228173291	[]	[]	-5	hSpCas9	negative selection	3596379
187378991	187379014	2	-	26780180	A375	viability (Avana lentiGuide)	TACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	-6.80776966856731	[]	[]	-9	hSpCas9	negative selection	3596380
187380764	187380787	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	-0.10858910205567979	[5]	[5,3]	-2	hSpCas9	positive selection	3705034
187363484	187363507	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-0.11196638707322745	[5]	[5,3]	-2	hSpCas9	positive selection	3705035
187380461	187380484	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATACCTTCACTTTCTCGTGGG	CALCRL	ENSG00000064989	-0.281786672932715	[7]	[6,5]	-4	hSpCas9	positive selection	3705036
187383269	187383292	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-0.1786373179369097	[5]	[5,4]	-3	hSpCas9	positive selection	3705037
187383253	187383276	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGAGGACTCAATTCAGTTGGG	CALCRL	ENSG00000064989	0.25267895551461855	[6]	[7,7]	7	hSpCas9	positive selection	3705038
187378991	187379014	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	-0.02333996709898911	[6]	[6,5]	0	hSpCas9	positive selection	3705039
187380764	187380787	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.3218749023681143	[5]	[6,5]	8	hSpCas9	positive selection	3813641
187363484	187363507	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-0.3766286912294413	[5]	[3,2]	-5	hSpCas9	positive selection	3813642
187380461	187380484	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATACCTTCACTTTCTCGTGGG	CALCRL	ENSG00000064989	0.1888340995735911	[8]	[8,7]	4	hSpCas9	positive selection	3813643
187383269	187383292	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.16195376179395224	[5]	[4,5]	4	hSpCas9	positive selection	3813644
187383253	187383276	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGAGGACTCAATTCAGTTGGG	CALCRL	ENSG00000064989	0.27384235872766866	[7]	[7,7]	7	hSpCas9	positive selection	3813645
187378991	187379014	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.44528571241695425	[5]	[6,6]	9	hSpCas9	positive selection	3813646
187380460	187380483	2	+	26780180	A375	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	1.08583143840408	[]	[]	5	hSpCas9	negative selection	3921938
187380765	187380788	2	-	26780180	A375	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	1.67703088148051	[]	[]	9	hSpCas9	negative selection	3921939
187380466	187380489	2	-	26780180	A375	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.974134446212617	[]	[]	4	hSpCas9	negative selection	3921940
187363373	187363396	2	+	26780180	A375	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.509465515892436	[]	[]	1	hSpCas9	negative selection	3921941
187380730	187380753	2	-	26780180	A375	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.849759345388976	[]	[]	3	hSpCas9	negative selection	3921942
187363484	187363507	2	-	26780180	A375	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.294228058733443	[]	[]	0	hSpCas9	negative selection	3921943
187380460	187380483	2	+	26780180	HT29	viability (GeCKOv2 library)	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	-0.0474025318049007	[]	[]	-1	hSpCas9	negative selection	4029904
187380765	187380788	2	-	26780180	HT29	viability (GeCKOv2 library)	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	2.01655355532894	[]	[]	9	hSpCas9	negative selection	4029905
187380466	187380489	2	-	26780180	HT29	viability (GeCKOv2 library)	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.965209632437266	[]	[]	4	hSpCas9	negative selection	4029906
187363373	187363396	2	+	26780180	HT29	viability (GeCKOv2 library)	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.632920262783695	[]	[]	2	hSpCas9	negative selection	4029907
187380730	187380753	2	-	26780180	HT29	viability (GeCKOv2 library)	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.616968612436154	[]	[]	2	hSpCas9	negative selection	4029908
187363484	187363507	2	-	26780180	HT29	viability (GeCKOv2 library)	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.443837736116259	[]	[]	1	hSpCas9	negative selection	4029909
187380460	187380483	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	-0.1395277969301847	[4]	[2,2]	-3	hSpCas9	positive selection	4188405
187380466	187380489	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.2646319637356593	[2]	[1,0]	-6	hSpCas9	positive selection	4188406
187380730	187380753	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.38159228854957705	[2]	[2,1]	8	hSpCas9	positive selection	4188407
187380460	187380483	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	1.0958316907652115	[4]	[2,5,4,4]	8	hSpCas9	positive selection	4252427
187380466	187380489	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.09816703549682373	[3]	[1,0,3,0]	-1	hSpCas9	positive selection	4252428
187380730	187380753	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	1.2261751748712761	[2]	[0,2,4,3]	8	hSpCas9	positive selection	4252429
187380730	187380753	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.3040467508615697	[3]	[4,3]	6	hSpCas9	positive selection	4260707
187363373	187363396	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.2829075423251912	[3]	[3,3]	6	hSpCas9	positive selection	4260708
187380460	187380483	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.08514011765088876	[2]	[3,1]	1	hSpCas9	positive selection	4260709
187380765	187380788	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.5368688251106121	[3]	[1,0]	-8	hSpCas9	positive selection	4324987
187380466	187380489	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.21291795572823402	[2]	[2,2]	4	hSpCas9	positive selection	4324988
187363484	187363507	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.6215133072459252	[3]	[3,4]	9	hSpCas9	positive selection	4324989
187363484	187363506	2	-	27760321	OCIAML3	viability	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.3734001249418808	[422,283]	[277,451]	4	hSpCas9	negative selection	4385301
187378991	187379013	2	-	27760321	OCIAML3	viability	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	1.2359444845502434	[287,219]	[452,478]	9	hSpCas9	negative selection	4385302
187380480	187380502	2	+	27760321	OCIAML3	viability	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	-0.12139642562750597	[38,29]	[31,14]	-1	hSpCas9	negative selection	4385303
187380730	187380752	2	-	27760321	OCIAML3	viability	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.20809608670923596	[584,464]	[252,483]	-2	hSpCas9	negative selection	4385304
187380764	187380786	2	-	27760321	OCIAML3	viability	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	-0.1266658654597561	[269,219]	[148,207]	-1	hSpCas9	negative selection	4385305
187363484	187363506	2	-	27760321	OCIAML2	viability	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.5750938119084887	[422,283]	[360,498]	7	hSpCas9	negative selection	4468764
187378991	187379013	2	-	27760321	OCIAML2	viability	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.522430408523783	[287,219]	[228,376]	7	hSpCas9	negative selection	4468765
187380480	187380502	2	+	27760321	OCIAML2	viability	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	1.7694028050214197	[38,29]	[71,123]	9	hSpCas9	negative selection	4468766
187380730	187380752	2	-	27760321	OCIAML2	viability	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.008904229213231835	[584,464]	[343,518]	0	hSpCas9	negative selection	4468767
187380764	187380786	2	-	27760321	OCIAML2	viability	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.2957420003641158	[269,219]	[213,278]	4	hSpCas9	negative selection	4468768
187363484	187363506	2	-	27760321	MV411	viability	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-0.31386339356307663	[422,283]	[8,449]	-2	hSpCas9	negative selection	4552227
187378991	187379013	2	-	27760321	MV411	viability	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.07169364120039656	[287,219]	[171,178]	0	hSpCas9	negative selection	4552228
187380480	187380502	2	+	27760321	MV411	viability	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	-4.498096861762832	[38,29]	[0,0]	-9	hSpCas9	negative selection	4552229
187380730	187380752	2	-	27760321	MV411	viability	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	1.496619072602857	[584,464]	[1029,883]	9	hSpCas9	negative selection	4552230
187380764	187380786	2	-	27760321	MV411	viability	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	-0.5741086023694242	[269,219]	[161,26]	-4	hSpCas9	negative selection	4552231
187363484	187363506	2	-	27760321	HL60	viability	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-0.040718351076227954	[422,283]	[247,307]	0	hSpCas9	negative selection	4635690
187378991	187379013	2	-	27760321	HL60	viability	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.43048382865459517	[287,219]	[259,295]	5	hSpCas9	negative selection	4635691
187380480	187380502	2	+	27760321	HL60	viability	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.6380168524052734	[38,29]	[27,59]	7	hSpCas9	negative selection	4635692
187380730	187380752	2	-	27760321	HL60	viability	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.6011936275023573	[584,464]	[649,642]	7	hSpCas9	negative selection	4635693
187380764	187380786	2	-	27760321	HL60	viability	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	3.4395860514587344	[269,219]	[895,3500]	9	hSpCas9	negative selection	4635694
187363484	187363506	2	-	27760321	HT1080	viability	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.8324252571244852	[283,221]	[115,248]	4	hSpCas9	negative selection	4719153
187378991	187379013	2	-	27760321	HT1080	viability	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	1.108826040602625	[219,171]	[271,54]	6	hSpCas9	negative selection	4719154
187380480	187380502	2	+	27760321	HT1080	viability	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	1.388806908376508	[29,23]	[0,57]	7	hSpCas9	negative selection	4719155
187380730	187380752	2	-	27760321	HT1080	viability	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.5329660026881586	[464,362]	[251,223]	3	hSpCas9	negative selection	4719156
187380764	187380786	2	-	27760321	HT1080	viability	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	-1.5527865044660696	[219,171]	[7,46]	-5	hSpCas9	negative selection	4719157
187363484	187363506	2	-	27760321	HT29	viability after 7 days	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.28657739304494956	[283,221]	[426,206,554]	4	hSpCas9	negative selection	4802616
187378991	187379013	2	-	27760321	HT29	viability after 7 days	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.2953971747683185	[219,171]	[336,272,320]	4	hSpCas9	negative selection	4802617
187380480	187380502	2	+	27760321	HT29	viability after 7 days	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.04703982314296562	[29,23]	[89,7,17]	0	hSpCas9	negative selection	4802618
187380730	187380752	2	-	27760321	HT29	viability after 7 days	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.11521685557364597	[464,362]	[728,554,469]	1	hSpCas9	negative selection	4802619
187380764	187380786	2	-	27760321	HT29	viability after 7 days	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.05093323812248074	[219,171]	[394,146,259]	0	hSpCas9	negative selection	4802620
187363484	187363506	2	-	27760321	HT29	viability after 25 days	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.7825692481817716	[283,221]	[320,585,606]	8	hSpCas9	negative selection	4886079
187378991	187379013	2	-	27760321	HT29	viability after 25 days	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.5931115316985455	[219,171]	[360,319,329]	6	hSpCas9	negative selection	4886080
187380480	187380502	2	+	27760321	HT29	viability after 25 days	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	-0.00470710848523348	[29,23]	[20,40,30]	0	hSpCas9	negative selection	4886081
187380730	187380752	2	-	27760321	HT29	viability after 25 days	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.7980865965396692	[464,362]	[898,860,687]	8	hSpCas9	negative selection	4886082
187380764	187380786	2	-	27760321	HT29	viability after 25 days	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	-0.03663920935152998	[219,171]	[125,304,230]	0	hSpCas9	negative selection	4886083
187363484	187363506	2	-	27760321	HT29	viability after 22 days	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.9269387266475468	[283,221]	[695,368,599]	9	hSpCas9	negative selection	4969542
187378991	187379013	2	-	27760321	HT29	viability after 22 days	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.582026567511041	[219,171]	[238,375,405]	6	hSpCas9	negative selection	4969543
187380480	187380502	2	+	27760321	HT29	viability after 22 days	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.09528065470840863	[29,23]	[0,72,26]	0	hSpCas9	negative selection	4969544
187380730	187380752	2	-	27760321	HT29	viability after 22 days	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.6557715317335711	[464,362]	[1052,549,649]	7	hSpCas9	negative selection	4969545
187380764	187380786	2	-	27760321	HT29	viability after 22 days	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.4955666417462318	[219,171]	[179,277,505]	5	hSpCas9	negative selection	4969546
187363484	187363506	2	-	27760321	HT29	viability after 19 days	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.4733881143849777	[283,221]	[709,251,279]	4	hSpCas9	negative selection	5053005
187378991	187379013	2	-	27760321	HT29	viability after 19 days	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.25689421551812874	[219,171]	[218,221,353]	2	hSpCas9	negative selection	5053006
187380480	187380502	2	+	27760321	HT29	viability after 19 days	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	-0.9845572168637089	[29,23]	[24,10,11]	-6	hSpCas9	negative selection	5053007
187380730	187380752	2	-	27760321	HT29	viability after 19 days	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.9001340254567732	[464,362]	[765,719,1141]	8	hSpCas9	negative selection	5053008
187380764	187380786	2	-	27760321	HT29	viability after 19 days	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.49193938479386917	[219,171]	[255,356,325]	5	hSpCas9	negative selection	5053009
187363484	187363506	2	-	27760321	HT29	viability after 16 days	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.5175661925608694	[283,221]	[461,444,312]	6	hSpCas9	negative selection	5136468
187378991	187379013	2	-	27760321	HT29	viability after 16 days	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.5557409536060411	[219,171]	[265,579,108]	6	hSpCas9	negative selection	5136469
187380480	187380502	2	+	27760321	HT29	viability after 16 days	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.5821710509183027	[29,23]	[8,23,99]	6	hSpCas9	negative selection	5136470
187380730	187380752	2	-	27760321	HT29	viability after 16 days	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.260672453282139	[464,362]	[696,481,500]	3	hSpCas9	negative selection	5136471
187380764	187380786	2	-	27760321	HT29	viability after 16 days	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.486203057188523	[219,171]	[478,221,238]	5	hSpCas9	negative selection	5136472
187363484	187363506	2	-	27760321	HT29	viability after 13 days	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.47247163345313636	[283,221]	[447,252,513]	6	hSpCas9	negative selection	5219931
187378991	187379013	2	-	27760321	HT29	viability after 13 days	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.8045319555528816	[219,171]	[428,562,210]	9	hSpCas9	negative selection	5219932
187380480	187380502	2	+	27760321	HT29	viability after 13 days	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.9370833390570494	[29,23]	[33,64,79]	9	hSpCas9	negative selection	5219933
187380730	187380752	2	-	27760321	HT29	viability after 13 days	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.4246173298303926	[464,362]	[632,879,433]	5	hSpCas9	negative selection	5219934
187380764	187380786	2	-	27760321	HT29	viability after 13 days	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.20746389774261786	[219,171]	[165,360,260]	2	hSpCas9	negative selection	5219935
187363484	187363506	2	-	27760321	HT29	viability after 10 days	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.4136403460419298	[283,221]	[331,372,552]	5	hSpCas9	negative selection	5303394
187378991	187379013	2	-	27760321	HT29	viability after 10 days	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	0.3078436319676784	[219,171]	[290,351,267]	4	hSpCas9	negative selection	5303395
187380480	187380502	2	+	27760321	HT29	viability after 10 days	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	-0.4028720343400911	[29,23]	[10,59,6]	-5	hSpCas9	negative selection	5303396
187380730	187380752	2	-	27760321	HT29	viability after 10 days	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.6362852780324609	[464,362]	[729,671,999]	8	hSpCas9	negative selection	5303397
187380764	187380786	2	-	27760321	HT29	viability after 10 days	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.04074698090135764	[219,171]	[155,209,384]	0	hSpCas9	negative selection	5303398
187363484	187363506	2	-	27760321	MOLM13	viability	TAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	1.1250656314664529	[422,283]	[712,187]	7	hSpCas9	negative selection	5386857
187378991	187379013	2	-	27760321	MOLM13	viability	ACCTGACCATAATTGGACACGG	CALCRL	ENSG00000064989	-0.13870175888524738	[287,219]	[173,90]	-1	hSpCas9	negative selection	5386858
187380480	187380502	2	+	27760321	MOLM13	viability	TGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.6983257664356337	[38,29]	[66,0]	5	hSpCas9	negative selection	5386859
187380730	187380752	2	-	27760321	MOLM13	viability	GCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.72666286321062	[584,464]	[457,511]	5	hSpCas9	negative selection	5386860
187380764	187380786	2	-	27760321	MOLM13	viability	GTTTACTGCAACAGAACCTGGG	CALCRL	ENSG00000064989	0.4733757434077595	[269,219]	[285,109]	3	hSpCas9	negative selection	5386861
187448115	187448138	2	+	27661255	K562	viability	GATTTACCCACAAGCAAGGTGGG	CALCRL	ENSG00000064989	0.06672041132187512	[525,472]	[395,437]	2	dCas9-KRAB	negative selection	5467830
187447791	187447814	2	-	27661255	K562	viability	GCAAGTATTAAAAATCTAAATGG	CALCRL	ENSG00000064989	-0.013149501269587138	[565,597]	[463,456]	0	dCas9-KRAB	negative selection	5467831
187380730	187380753	2	-	27260156	BXPC3	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.1784870025567138	[902]	[1057,1034,1035,1149]	4	hSpCas9	negative selection	5533167
187363373	187363396	2	+	27260156	BXPC3	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.19883160410415496	[628]	[640,747,804,844]	4	hSpCas9	negative selection	5533168
187380460	187380483	2	+	27260156	BXPC3	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.49768534724705943	[356]	[439,466,532,698]	9	hSpCas9	negative selection	5533169
187380765	187380788	2	-	27260156	BXPC3	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.017444375222300523	[588]	[635,567,585,710]	0	hSpCas9	negative selection	5597447
187380466	187380489	2	-	27260156	BXPC3	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.033009837639958683	[351]	[364,404,287,452]	0	hSpCas9	negative selection	5597448
187363484	187363507	2	-	27260156	BXPC3	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.1376430824420548	[691]	[613,790,952,849]	3	hSpCas9	negative selection	5597449
187380730	187380753	2	-	27260156	A673	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.04981208752705335	[902]	[1350,903,919,1052]	-1	hSpCas9	negative selection	5654418
187363373	187363396	2	+	27260156	A673	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.02934725820720191	[628]	[869,716,630,883]	0	hSpCas9	negative selection	5654419
187380460	187380483	2	+	27260156	A673	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.5006790057807444	[356]	[755,520,585,579]	9	hSpCas9	negative selection	5654420
187380765	187380788	2	-	27260156	A673	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.0038971162144145755	[588]	[817,624,688,702]	0	hSpCas9	negative selection	5718698
187380466	187380489	2	-	27260156	A673	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.019589790205217672	[351]	[468,341,412,452]	0	hSpCas9	negative selection	5718699
187363484	187363507	2	-	27260156	A673	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.24648479963908299	[691]	[953,912,1146,919]	6	hSpCas9	negative selection	5718700
187380730	187380753	2	-	27260156	A375	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.4505538948224326	[902]	[1543,1641,1287,1327]	6	hSpCas9	negative selection	5775669
187363373	187363396	2	+	27260156	A375	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.2703532538495393	[628]	[904,976,1065,635]	4	hSpCas9	negative selection	5775670
187380460	187380483	2	+	27260156	A375	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.6709993823216707	[356]	[687,847,628,529]	8	hSpCas9	negative selection	5775671
187380765	187380788	2	-	27260156	A375	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.01670077458562158	[588]	[582,876,722,573]	0	hSpCas9	negative selection	5839949
187380466	187380489	2	-	27260156	A375	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.09128787263956123	[351]	[523,323,531,363]	1	hSpCas9	negative selection	5839950
187363484	187363507	2	-	27260156	A375	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.4102988933978565	[691]	[903,1441,1113,902]	6	hSpCas9	negative selection	5839951
187380730	187380753	2	-	27260156	COLO741	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.21786528056995103	[902]	[1591,1189,1266]	4	hSpCas9	negative selection	5896920
187363373	187363396	2	+	27260156	COLO741	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.07499289372665685	[628]	[851,947,745]	1	hSpCas9	negative selection	5896921
187380460	187380483	2	+	27260156	COLO741	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.5255710103982522	[356]	[783,650,551]	9	hSpCas9	negative selection	5896922
187380765	187380788	2	-	27260156	COLO741	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.04879872477595837	[588]	[893,695,754]	1	hSpCas9	negative selection	5961200
187380466	187380489	2	-	27260156	COLO741	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.1848600801701386	[351]	[466,398,330]	-4	hSpCas9	negative selection	5961201
187363484	187363507	2	-	27260156	COLO741	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.2094846165015305	[691]	[1155,955,967]	4	hSpCas9	negative selection	5961202
187380730	187380753	2	-	27260156	CAL120	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.1876502319883706	[902]	[1435,1018,1404]	3	hSpCas9	negative selection	6018171
187363373	187363396	2	+	27260156	CAL120	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.31205708794483805	[628]	[1186,778,980]	5	hSpCas9	negative selection	6018172
187380460	187380483	2	+	27260156	CAL120	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.4642411928426031	[356]	[816,489,562]	7	hSpCas9	negative selection	6018173
187380765	187380788	2	-	27260156	CAL120	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.398337734567716	[588]	[1473,809,694]	6	hSpCas9	negative selection	6082451
187380466	187380489	2	-	27260156	CAL120	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.08412409860317027	[351]	[187,854,310]	1	hSpCas9	negative selection	6082452
187363484	187363507	2	-	27260156	CAL120	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.05935648916145775	[691]	[940,688,1064]	0	hSpCas9	negative selection	6082453
187380730	187380753	2	-	27260156	CADOES1	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.41646437198604525	[902]	[1271,940,1169,1098]	7	hSpCas9	negative selection	6139422
187363373	187363396	2	+	27260156	CADOES1	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.47039315931112474	[628]	[638,829,695,1087]	7	hSpCas9	negative selection	6139423
187380460	187380483	2	+	27260156	CADOES1	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.43887562481968906	[356]	[499,379,394,527]	7	hSpCas9	negative selection	6139424
187380765	187380788	2	-	27260156	CADOES1	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.15734737003388488	[588]	[849,512,492,585]	2	hSpCas9	negative selection	6203702
187380466	187380489	2	-	27260156	CADOES1	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.06456616517114616	[351]	[421,476,244,220]	1	hSpCas9	negative selection	6203703
187363484	187363507	2	-	27260156	CADOES1	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.13677373995672149	[691]	[719,705,578,829]	2	hSpCas9	negative selection	6203704
187380730	187380753	2	-	27260156	EWS502	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.14754112372483763	[902]	[891,979,1359,1026]	2	hSpCas9	negative selection	6260673
187363373	187363396	2	+	27260156	EWS502	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.11079361482099254	[628]	[684,607,883,707]	2	hSpCas9	negative selection	6260674
187380460	187380483	2	+	27260156	EWS502	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.3465996675543036	[356]	[414,357,605,562]	6	hSpCas9	negative selection	6260675
187380765	187380788	2	-	27260156	EWS502	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.10786340085348775	[588]	[554,495,598,676]	-2	hSpCas9	negative selection	6324953
187380466	187380489	2	-	27260156	EWS502	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.033200588451497426	[351]	[448,418,197,375]	0	hSpCas9	negative selection	6324954
187363484	187363507	2	-	27260156	EWS502	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.38920515649522325	[691]	[886,836,1019,1117]	6	hSpCas9	negative selection	6324955
187380730	187380753	2	-	27260156	EW8	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.1738708907722204	[902]	[887,863,759,805]	3	hSpCas9	negative selection	6381924
187363373	187363396	2	+	27260156	EW8	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.47611900929067824	[628]	[752,646,538,927]	8	hSpCas9	negative selection	6381925
187380460	187380483	2	+	27260156	EW8	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.7283399541730711	[356]	[580,553,346,467]	9	hSpCas9	negative selection	6381926
187380765	187380788	2	-	27260156	EW8	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.1209923921197184	[588]	[474,489,576,517]	2	hSpCas9	negative selection	6446204
187380466	187380489	2	-	27260156	EW8	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.4559865341853887	[351]	[670,342,284,313]	7	hSpCas9	negative selection	6446205
187363484	187363507	2	-	27260156	EW8	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.30764500539366557	[691]	[651,825,571,740]	5	hSpCas9	negative selection	6446206
187380730	187380753	2	-	27260156	CORL105	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.19506514848766643	[902]	[1139,1057,1591,1110]	3	hSpCas9	negative selection	6503175
187363373	187363396	2	+	27260156	CORL105	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.1809092370024626	[628]	[880,817,942,715]	3	hSpCas9	negative selection	6503176
187380460	187380483	2	+	27260156	CORL105	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.4221418190220044	[356]	[649,479,731,409]	7	hSpCas9	negative selection	6503177
187380765	187380788	2	-	27260156	CORL105	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.15431102714100375	[588]	[746,581,1052,734]	3	hSpCas9	negative selection	6567455
187380466	187380489	2	-	27260156	CORL105	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.2987891285365689	[351]	[465,454,658,470]	5	hSpCas9	negative selection	6567456
187363484	187363507	2	-	27260156	CORL105	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.19553017880828893	[691]	[959,1083,900,759]	3	hSpCas9	negative selection	6567457
187380730	187380753	2	-	27260156	HS294T	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.5292425968528016	[902]	[541,395,435,666]	7	hSpCas9	negative selection	6624426
187363373	187363396	2	+	27260156	HS294T	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	-0.09249245195653194	[628]	[191,207,296,216]	-1	hSpCas9	negative selection	6624427
187380460	187380483	2	+	27260156	HS294T	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.231504578788427	[356]	[129,146,128,261]	3	hSpCas9	negative selection	6624428
187380765	187380788	2	-	27260156	HS294T	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.001546753170951265	[588]	[235,209,186,287]	0	hSpCas9	negative selection	6688706
187380466	187380489	2	-	27260156	HS294T	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.11091591281228858	[351]	[132,130,194,126]	1	hSpCas9	negative selection	6688707
187363484	187363507	2	-	27260156	HS294T	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.010783625180576073	[691]	[175,261,332,324]	0	hSpCas9	negative selection	6688708
187380730	187380753	2	-	27260156	HCC44	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.5558745058311669	[902]	[1331,1330,1902,1504]	8	hSpCas9	negative selection	6745677
187363373	187363396	2	+	27260156	HCC44	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.5301513162961913	[628]	[1179,849,1261,892]	8	hSpCas9	negative selection	6745678
187380460	187380483	2	+	27260156	HCC44	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.517912205181766	[356]	[636,637,413,586]	8	hSpCas9	negative selection	6745679
187380765	187380788	2	-	27260156	HCC44	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.06075718234582028	[588]	[649,660,795,684]	0	hSpCas9	negative selection	6809957
187380466	187380489	2	-	27260156	HCC44	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.023465906027631656	[351]	[409,434,435,337]	0	hSpCas9	negative selection	6809958
187363484	187363507	2	-	27260156	HCC44	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.01315662623453584	[691]	[893,711,780,784]	0	hSpCas9	negative selection	6809959
187380730	187380753	2	-	27260156	G402	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.5145140465076965	[902]	[2155,1780,1066,1390]	6	hSpCas9	negative selection	6866928
187363373	187363396	2	+	27260156	G402	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.23389836721220097	[628]	[1485,762,933,518]	3	hSpCas9	negative selection	6866929
187380460	187380483	2	+	27260156	G402	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.30311984645582923	[356]	[663,383,759,357]	4	hSpCas9	negative selection	6866930
187380765	187380788	2	-	27260156	G402	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.6611400264369103	[588]	[1059,1447,826,1209]	7	hSpCas9	negative selection	6931208
187380466	187380489	2	-	27260156	G402	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.2979429849253227	[351]	[466,1130,172,372]	4	hSpCas9	negative selection	6931209
187363484	187363507	2	-	27260156	G402	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.1830134076270189	[691]	[1381,1188,647,698]	2	hSpCas9	negative selection	6931210
187380730	187380753	2	-	27260156	L33	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.18756439907932498	[902]	[866,529,638,940]	4	hSpCas9	negative selection	6988179
187363373	187363396	2	+	27260156	L33	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	-0.03997014316174391	[628]	[529,237,373,741]	-1	hSpCas9	negative selection	6988180
187380460	187380483	2	+	27260156	L33	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.2614711416480637	[356]	[391,170,280,455]	5	hSpCas9	negative selection	6988181
187380765	187380788	2	-	27260156	L33	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.19303147029504325	[588]	[648,331,409,582]	4	hSpCas9	negative selection	7052459
187380466	187380489	2	-	27260156	L33	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.01481317863491971	[351]	[431,144,202,311]	0	hSpCas9	negative selection	7052460
187363484	187363507	2	-	27260156	L33	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.4352247739077372	[691]	[1036,305,615,975]	8	hSpCas9	negative selection	7052461
187380730	187380753	2	-	27260156	K562	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.08052250051313536	[902]	[1078,1066,495,781]	1	hSpCas9	negative selection	7109430
187363373	187363396	2	+	27260156	K562	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.7828966062946789	[628]	[831,1047,1154,813]	8	hSpCas9	negative selection	7109431
187380460	187380483	2	+	27260156	K562	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.8268961517491933	[356]	[403,314,1045,465]	9	hSpCas9	negative selection	7109432
187380765	187380788	2	-	27260156	K562	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.3706046291792366	[588]	[871,844,735,314]	5	hSpCas9	negative selection	7173710
187380466	187380489	2	-	27260156	K562	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.7036854725847197	[351]	[190,251,233,102]	-7	hSpCas9	negative selection	7173711
187363484	187363507	2	-	27260156	K562	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.34082228844219453	[691]	[984,800,723,632]	4	hSpCas9	negative selection	7173712
187380730	187380753	2	-	27260156	HT29	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.17418430359207893	[902]	[1387,1206,1335,1046]	3	hSpCas9	negative selection	7230681
187363373	187363396	2	+	27260156	HT29	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.22031748976852933	[628]	[1163,829,791,797]	4	hSpCas9	negative selection	7230682
187380460	187380483	2	+	27260156	HT29	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.41326095153274345	[356]	[522,500,688,582]	7	hSpCas9	negative selection	7230683
187380765	187380788	2	-	27260156	HT29	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.0025370634594704122	[588]	[649,863,682,678]	0	hSpCas9	negative selection	7294961
187380466	187380489	2	-	27260156	HT29	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.12709482082883883	[351]	[398,526,582,368]	2	hSpCas9	negative selection	7294962
187363484	187363507	2	-	27260156	HT29	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.1508336160809448	[691]	[966,795,1241,738]	3	hSpCas9	negative selection	7294963
187380730	187380753	2	-	27260156	MHHES1	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.13670348054514725	[902]	[1010,1325,1116,1022]	2	hSpCas9	negative selection	7351932
187363373	187363396	2	+	27260156	MHHES1	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.23246416628903405	[628]	[945,1010,799,631]	4	hSpCas9	negative selection	7351933
187380460	187380483	2	+	27260156	MHHES1	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.4802762032727902	[356]	[610,696,505,459]	8	hSpCas9	negative selection	7351934
187380765	187380788	2	-	27260156	MHHES1	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.1521473060234217	[588]	[654,892,718,682]	3	hSpCas9	negative selection	7416212
187380466	187380489	2	-	27260156	MHHES1	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.055791110121757914	[351]	[316,668,409,286]	1	hSpCas9	negative selection	7416213
187363484	187363507	2	-	27260156	MHHES1	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.3940922850901287	[691]	[1087,1025,1092,902]	7	hSpCas9	negative selection	7416214
187380730	187380753	2	-	27260156	MEWO	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.051385864597409237	[902]	[982,829,664]	-1	hSpCas9	negative selection	7473183
187363373	187363396	2	+	27260156	MEWO	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.24320031114046609	[628]	[621,894,556]	5	hSpCas9	negative selection	7473184
187380460	187380483	2	+	27260156	MEWO	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.619174669470486	[356]	[557,440,548]	9	hSpCas9	negative selection	7473185
187380765	187380788	2	-	27260156	MEWO	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.10834482589598612	[588]	[544,505,488]	-2	hSpCas9	negative selection	7537463
187380466	187380489	2	-	27260156	MEWO	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.3454592798364481	[351]	[540,398,338]	7	hSpCas9	negative selection	7537464
187363484	187363507	2	-	27260156	MEWO	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.04168289977343764	[691]	[850,620,562]	0	hSpCas9	negative selection	7537465
187380730	187380753	2	-	27260156	LNCAPCLONEFGC	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.4011514241963017	[902]	[1215,881,1116,1120]	6	hSpCas9	negative selection	7594434
187363373	187363396	2	+	27260156	LNCAPCLONEFGC	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.3938552138245888	[628]	[688,904,661,715]	6	hSpCas9	negative selection	7594435
187380460	187380483	2	+	27260156	LNCAPCLONEFGC	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.6019216038230663	[356]	[490,395,549,540]	8	hSpCas9	negative selection	7594436
187380765	187380788	2	-	27260156	LNCAPCLONEFGC	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.11338181114714341	[588]	[570,437,528,441]	-2	hSpCas9	negative selection	7658714
187380466	187380489	2	-	27260156	LNCAPCLONEFGC	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.2536020051039786	[351]	[222,314,469,532]	4	hSpCas9	negative selection	7658715
187363484	187363507	2	-	27260156	LNCAPCLONEFGC	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.3711413950782336	[691]	[735,862,1056,620]	6	hSpCas9	negative selection	7658716
187380730	187380753	2	-	27260156	PANC0327	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.10794849575592913	[902]	[821,666,1104,885]	1	hSpCas9	negative selection	7715685
187363373	187363396	2	+	27260156	PANC0327	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.6281898768664502	[628]	[1222,587,759,947]	8	hSpCas9	negative selection	7715686
187380460	187380483	2	+	27260156	PANC0327	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	-0.004400190317380315	[356]	[226,300,262,467]	0	hSpCas9	negative selection	7715687
187380765	187380788	2	-	27260156	PANC0327	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.07093118440789331	[588]	[497,507,490,493]	-1	hSpCas9	negative selection	7779965
187380466	187380489	2	-	27260156	PANC0327	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.3565877687770353	[351]	[221,203,205,347]	-5	hSpCas9	negative selection	7779966
187363484	187363507	2	-	27260156	PANC0327	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.3408223420555573	[691]	[918,662,668,888]	5	hSpCas9	negative selection	7779967
187380730	187380753	2	-	27260156	NCIH2009	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.554196658617601	[902]	[2076,1509,2017]	7	hSpCas9	negative selection	7836936
187363373	187363396	2	+	27260156	NCIH2009	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.3259594565930832	[628]	[1545,1031,813]	4	hSpCas9	negative selection	7836937
187380460	187380483	2	+	27260156	NCIH2009	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.750410842783672	[356]	[896,579,1054]	9	hSpCas9	negative selection	7836938
187380765	187380788	2	-	27260156	NCIH2009	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.19039553634775913	[588]	[1040,697,1100]	2	hSpCas9	negative selection	7901216
187380466	187380489	2	-	27260156	NCIH2009	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.09887244319333871	[351]	[533,449,597]	1	hSpCas9	negative selection	7901217
187363484	187363507	2	-	27260156	NCIH2009	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-0.03203571567845387	[691]	[1158,800,919]	0	hSpCas9	negative selection	7901218
187380730	187380753	2	-	27260156	NCIH1373	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.4081820552982256	[902]	[2061,1324,1009,281]	4	hSpCas9	negative selection	7958187
187363373	187363396	2	+	27260156	NCIH1373	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.2994068860160402	[628]	[840,520,900,330]	3	hSpCas9	negative selection	7958188
187380460	187380483	2	+	27260156	NCIH1373	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	-0.2543099039251358	[356]	[331,266,414,86]	-3	hSpCas9	negative selection	7958189
187380765	187380788	2	-	27260156	NCIH1373	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.2561619816080382	[588]	[1471,557,564,179]	2	hSpCas9	negative selection	8022467
187380466	187380489	2	-	27260156	NCIH1373	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.11747041066888947	[351]	[371,468,273,85]	-1	hSpCas9	negative selection	8022468
187363484	187363507	2	-	27260156	NCIH1373	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	-0.07414527589198622	[691]	[615,841,681,203]	0	hSpCas9	negative selection	8022469
187380730	187380753	2	-	27260156	PATU8902	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.5389683243030514	[902]	[2382,2544,818,1800]	5	hSpCas9	negative selection	8079438
187363373	187363396	2	+	27260156	PATU8902	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.4108198748444339	[628]	[1409,1155,602,1684]	4	hSpCas9	negative selection	8079439
187380460	187380483	2	+	27260156	PATU8902	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.6004384020090032	[356]	[798,671,515,1127]	6	hSpCas9	negative selection	8079440
187380765	187380788	2	-	27260156	PATU8902	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.5963656886030577	[588]	[958,936,1142,2034]	6	hSpCas9	negative selection	8143718
187380466	187380489	2	-	27260156	PATU8902	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.3470833057828106	[351]	[301,848,651,691]	3	hSpCas9	negative selection	8143719
187363484	187363507	2	-	27260156	PATU8902	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.42214077279646767	[691]	[1883,1352,766,1277]	4	hSpCas9	negative selection	8143720
187380730	187380753	2	-	27260156	PANC1	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.1362001040617984	[902]	[934,896,760,814]	2	hSpCas9	negative selection	8200689
187363373	187363396	2	+	27260156	PANC1	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.5184223871678995	[628]	[718,629,1055,668]	8	hSpCas9	negative selection	8200690
187380460	187380483	2	+	27260156	PANC1	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.608868966558106	[356]	[490,426,515,426]	8	hSpCas9	negative selection	8200691
187380765	187380788	2	-	27260156	PANC1	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.20063108890951858	[588]	[702,759,577,347]	3	hSpCas9	negative selection	8264969
187380466	187380489	2	-	27260156	PANC1	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.05792757976794716	[351]	[210,336,306,309]	-1	hSpCas9	negative selection	8264970
187363484	187363507	2	-	27260156	PANC1	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.37729618018937205	[691]	[867,1133,693,496]	6	hSpCas9	negative selection	8264971
187380730	187380753	2	-	27260156	PANC0813	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.3213973268731103	[902]	[1001,1347,1616,1304]	5	hSpCas9	negative selection	8321940
187363373	187363396	2	+	27260156	PANC0813	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.06481281962373348	[628]	[830,799,778,689]	1	hSpCas9	negative selection	8321941
187380460	187380483	2	+	27260156	PANC0813	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.15369448288629028	[356]	[394,488,563,413]	2	hSpCas9	negative selection	8321942
187380765	187380788	2	-	27260156	PANC0813	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.08019090255227929	[588]	[894,530,1006,519]	1	hSpCas9	negative selection	8386220
187380466	187380489	2	-	27260156	PANC0813	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.40611362012265956	[351]	[509,501,668,508]	6	hSpCas9	negative selection	8386221
187363484	187363507	2	-	27260156	PANC0813	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.17009531259465804	[691]	[794,725,1258,869]	2	hSpCas9	negative selection	8386222
187380730	187380753	2	-	27260156	RDES	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.19527631901541675	[902]	[983,1152,1163,1514]	3	hSpCas9	negative selection	8443191
187363373	187363396	2	+	27260156	RDES	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.4458669773497615	[628]	[732,954,1098,1223]	7	hSpCas9	negative selection	8443192
187380460	187380483	2	+	27260156	RDES	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.4083417383117817	[356]	[433,590,546,621]	6	hSpCas9	negative selection	8443193
187380765	187380788	2	-	27260156	RDES	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.1755550891298357	[588]	[549,757,772,1047]	3	hSpCas9	negative selection	8507471
187380466	187380489	2	-	27260156	RDES	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.15812206465582257	[351]	[300,336,551,688]	2	hSpCas9	negative selection	8507472
187363484	187363507	2	-	27260156	RDES	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.2008439754680731	[691]	[778,870,972,1065]	3	hSpCas9	negative selection	8507473
187380730	187380753	2	-	27260156	PC3	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.10594505075852467	[902]	[541,886,1830,1061]	2	hSpCas9	negative selection	8564442
187363373	187363396	2	+	27260156	PC3	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.26543942789070957	[628]	[398,855,1288,764]	6	hSpCas9	negative selection	8564443
187380460	187380483	2	+	27260156	PC3	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.4918947625551552	[356]	[282,406,976,580]	8	hSpCas9	negative selection	8564444
187380765	187380788	2	-	27260156	PC3	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.06260016622784159	[588]	[285,641,959,586]	-1	hSpCas9	negative selection	8628722
187380466	187380489	2	-	27260156	PC3	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.07288214054997189	[351]	[195,255,836,273]	-2	hSpCas9	negative selection	8628723
187363484	187363507	2	-	27260156	PC3	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.21359062428271713	[691]	[515,809,1238,850]	5	hSpCas9	negative selection	8628724
187380730	187380753	2	-	27260156	PATU8988T	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.2909386511658083	[902]	[885,1019,1282,1073]	5	hSpCas9	negative selection	8685693
187363373	187363396	2	+	27260156	PATU8988T	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.06830331245050164	[628]	[544,761,654,594]	1	hSpCas9	negative selection	8685694
187380460	187380483	2	+	27260156	PATU8988T	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.6345812878867267	[356]	[431,712,405,615]	9	hSpCas9	negative selection	8685695
187380765	187380788	2	-	27260156	PATU8988T	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.04375448362540185	[588]	[565,656,344,661]	0	hSpCas9	negative selection	8749973
187380466	187380489	2	-	27260156	PATU8988T	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.04117877277524257	[351]	[234,566,212,330]	0	hSpCas9	negative selection	8749974
187363484	187363507	2	-	27260156	PATU8988T	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.47166424189617784	[691]	[958,992,878,880]	7	hSpCas9	negative selection	8749975
187380730	187380753	2	-	27260156	T47D	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.18684977375748058	[902]	[1239,1198,1175,1173]	4	hSpCas9	negative selection	8806944
187363373	187363396	2	+	27260156	T47D	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.37333693407892393	[628]	[992,891,953,962]	7	hSpCas9	negative selection	8806945
187380460	187380483	2	+	27260156	T47D	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.49435153374780766	[356]	[654,525,497,673]	9	hSpCas9	negative selection	8806946
187380765	187380788	2	-	27260156	T47D	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.005977055779049167	[588]	[769,659,652,651]	0	hSpCas9	negative selection	8871224
187380466	187380489	2	-	27260156	T47D	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.1605860327421253	[351]	[393,483,497,453]	3	hSpCas9	negative selection	8871225
187363484	187363507	2	-	27260156	T47D	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.3461447515137953	[691]	[1027,1002,969,1102]	7	hSpCas9	negative selection	8871226
187380730	187380753	2	-	27260156	SU8686	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.237680735716419	[902]	[1110,972,1014,1130]	4	hSpCas9	negative selection	8928195
187363373	187363396	2	+	27260156	SU8686	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.11902748305636529	[628]	[645,562,777,749]	2	hSpCas9	negative selection	8928196
187380460	187380483	2	+	27260156	SU8686	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.4527734166786484	[356]	[530,415,433,568]	7	hSpCas9	negative selection	8928197
187380765	187380788	2	-	27260156	SU8686	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.07590607271208027	[588]	[503,456,588,705]	-1	hSpCas9	negative selection	8992475
187380466	187380489	2	-	27260156	SU8686	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.1950978081820663	[351]	[403,347,380,480]	3	hSpCas9	negative selection	8992476
187363484	187363507	2	-	27260156	SU8686	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.5156124148092911	[691]	[899,879,1169,995]	8	hSpCas9	negative selection	8992477
187380730	187380753	2	-	27260156	SKES1	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.11368812109653303	[902]	[990,1138,917,874]	2	hSpCas9	negative selection	9049446
187363373	187363396	2	+	27260156	SKES1	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.1922124245491325	[628]	[997,725,645,550]	4	hSpCas9	negative selection	9049447
187380460	187380483	2	+	27260156	SKES1	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.5183560326899253	[356]	[650,708,457,287]	9	hSpCas9	negative selection	9049448
187380765	187380788	2	-	27260156	SKES1	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.07333993772508668	[588]	[575,561,711,397]	-2	hSpCas9	negative selection	9113726
187380466	187380489	2	-	27260156	SKES1	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.03626687524197003	[351]	[293,385,294,384]	-1	hSpCas9	negative selection	9113727
187363484	187363507	2	-	27260156	SKES1	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.4050436325260346	[691]	[1168,840,894,783]	8	hSpCas9	negative selection	9113728
187380730	187380753	2	-	27260156	TOV112D	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.12571580738421906	[902]	[781,924,905,723]	-2	hSpCas9	negative selection	9170697
187363373	187363396	2	+	27260156	TOV112D	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.28547245538344074	[628]	[741,1192,633,607]	5	hSpCas9	negative selection	9170698
187380460	187380483	2	+	27260156	TOV112D	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.5345308418909915	[356]	[587,583,477,444]	8	hSpCas9	negative selection	9170699
187380765	187380788	2	-	27260156	TOV112D	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.03654151400272376	[588]	[863,462,617,464]	0	hSpCas9	negative selection	9234977
187380466	187380489	2	-	27260156	TOV112D	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.3514744134512733	[351]	[452,513,269,573]	6	hSpCas9	negative selection	9234978
187363484	187363507	2	-	27260156	TOV112D	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.23046902600512342	[691]	[945,1201,612,602]	4	hSpCas9	negative selection	9234979
187380730	187380753	2	-	27260156	TC71	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.002593415459981596	[902]	[942,930,836,1185]	0	hSpCas9	negative selection	9291948
187363373	187363396	2	+	27260156	TC71	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.14160351161235446	[628]	[617,874,730,754]	3	hSpCas9	negative selection	9291949
187380460	187380483	2	+	27260156	TC71	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.44616962443748875	[356]	[636,479,449,517]	8	hSpCas9	negative selection	9291950
187380765	187380788	2	-	27260156	TC71	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	-0.23457656813010858	[588]	[481,639,561,457]	-6	hSpCas9	negative selection	9356228
187380466	187380489	2	-	27260156	TC71	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.008368898961647109	[351]	[470,386,356,277]	0	hSpCas9	negative selection	9356229
187363484	187363507	2	-	27260156	TC71	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.3165526480651839	[691]	[895,1069,922,798]	7	hSpCas9	negative selection	9356230
187380730	187380753	2	-	27260156	TC32	viability	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.24770092304829916	[902]	[873,735,1312,1233]	4	hSpCas9	negative selection	9413199
187363373	187363396	2	+	27260156	TC32	viability	TACAGGATTTGTGGCTACTAAGG	CALCRL	ENSG00000064989	0.5333824127367639	[628]	[711,758,1117,881]	8	hSpCas9	negative selection	9413200
187380460	187380483	2	+	27260156	TC32	viability	GACATACCTTCACTTTCTCGTGG	CALCRL	ENSG00000064989	0.6142526916417643	[356]	[313,412,749,660]	8	hSpCas9	negative selection	9413201
187380765	187380788	2	-	27260156	TC32	viability	GCGTTTACTGCAACAGAACCTGG	CALCRL	ENSG00000064989	0.001229668474577783	[588]	[547,433,679,589]	0	hSpCas9	negative selection	9477479
187380466	187380489	2	-	27260156	TC32	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.08440083191479791	[351]	[235,164,484,448]	-1	hSpCas9	negative selection	9477480
187363484	187363507	2	-	27260156	TC32	viability	TTAGGAGCCTAAGTTGCCAAAGG	CALCRL	ENSG00000064989	0.33215147998191186	[691]	[611,742,1038,929]	6	hSpCas9	negative selection	9477481
187346260	187346283	2	+	27869803	HPAFII	viability after 27 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.25569921764953657	[240]	[117,178,NaN]	2	hSpCas9	negative selection	9572654
187352163	187352186	2	+	27869803	HPAFII	viability after 27 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.5866640488909771	[113]	[52,28,NaN]	-4	hSpCas9	negative selection	9572655
187363378	187363401	2	+	27869803	HPAFII	viability after 27 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-1.7755202452284564	[73]	[6,14,NaN]	-8	hSpCas9	negative selection	9572656
187363396	187363419	2	-	27869803	HPAFII	viability after 27 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.004093348236490102	[458]	[175,296,NaN]	0	hSpCas9	negative selection	9572657
187380730	187380753	2	-	27869803	HPAFII	viability after 27 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.40526112978301587	[210]	[93,190,NaN]	3	hSpCas9	negative selection	9572658
187346260	187346283	2	+	27869803	HPAFII	viability after 15 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.4632664549296645	[240]	[390,335,NaN]	5	hSpCas9	negative selection	9655103
187352163	187352186	2	+	27869803	HPAFII	viability after 15 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.4610106077875108	[113]	[151,178,NaN]	5	hSpCas9	negative selection	9655104
187363378	187363401	2	+	27869803	HPAFII	viability after 15 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-1.3857857762866623	[73]	[43,21,NaN]	-8	hSpCas9	negative selection	9655105
187363396	187363419	2	-	27869803	HPAFII	viability after 15 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	-0.21213565724409944	[458]	[386,449,NaN]	-2	hSpCas9	negative selection	9655106
187380730	187380753	2	-	27869803	HPAFII	viability after 15 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.4455726763712524	[210]	[396,253,NaN]	5	hSpCas9	negative selection	9655107
187346260	187346283	2	+	27869803	ASPC1	viability after 36 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.25474610442777834	[447]	[406,110,89]	2	hSpCas9	negative selection	9737552
187352163	187352186	2	+	27869803	ASPC1	viability after 36 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	1.7651443314167632	[239]	[222,590,81]	9	hSpCas9	negative selection	9737553
187363378	187363401	2	+	27869803	ASPC1	viability after 36 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-1.0140947423969022	[164]	[55,35,2]	-7	hSpCas9	negative selection	9737554
187363396	187363419	2	-	27869803	ASPC1	viability after 36 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.48950267712843765	[1414]	[951,890,347]	5	hSpCas9	negative selection	9737555
187380730	187380753	2	-	27869803	ASPC1	viability after 36 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-1.7043961552639169	[405]	[34,79,19]	-9	hSpCas9	negative selection	9737556
187346260	187346283	2	+	27869803	PATU8988S	viability after 35 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	-0.8486758465836163	[471]	[131,78,NaN]	-7	hSpCas9	negative selection	9820001
187352163	187352186	2	+	27869803	PATU8988S	viability after 35 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.1534751550727591	[221]	[75,122,NaN]	1	hSpCas9	negative selection	9820002
187363378	187363401	2	+	27869803	PATU8988S	viability after 35 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.6654749929127934	[113]	[5,51,NaN]	-6	hSpCas9	negative selection	9820003
187363396	187363419	2	-	27869803	PATU8988S	viability after 35 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	-0.2837653713747018	[1128]	[379,366,NaN]	-3	hSpCas9	negative selection	9820004
187380730	187380753	2	-	27869803	PATU8988S	viability after 35 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.22051897904229634	[381]	[150,112,NaN]	-2	hSpCas9	negative selection	9820005
187346260	187346283	2	+	27869803	PATU8988S	viability after 31 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	-0.9622448934687949	[471]	[89,104,NaN]	-7	hSpCas9	negative selection	9902450
187352163	187352186	2	+	27869803	PATU8988S	viability after 31 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	0.3568261043041804	[221]	[115,109,NaN]	4	hSpCas9	negative selection	9902451
187363378	187363401	2	+	27869803	PATU8988S	viability after 31 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.039369080725740524	[113]	[18,81,NaN]	0	hSpCas9	negative selection	9902452
187363396	187363419	2	-	27869803	PATU8988S	viability after 31 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.13688248155566263	[1128]	[428,578,NaN]	1	hSpCas9	negative selection	9902453
187380730	187380753	2	-	27869803	PATU8988S	viability after 31 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.28516881672209987	[381]	[233,123,NaN]	3	hSpCas9	negative selection	9902454
187346260	187346283	2	+	27869803	HPAFII	viability after 35 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.882067743053178	[240]	[174,280,NaN]	6	hSpCas9	negative selection	9984899
187352163	187352186	2	+	27869803	HPAFII	viability after 35 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-1.1697922729758758	[113]	[35,13,NaN]	-6	hSpCas9	negative selection	9984900
187363378	187363401	2	+	27869803	HPAFII	viability after 35 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-3.5864768973131262	[73]	[4,0,NaN]	-9	hSpCas9	negative selection	9984901
187363396	187363419	2	-	27869803	HPAFII	viability after 35 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.006247476091824522	[458]	[159,315,NaN]	0	hSpCas9	negative selection	9984902
187380730	187380753	2	-	27869803	HPAFII	viability after 35 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	0.2838396033518291	[210]	[98,164,NaN]	1	hSpCas9	negative selection	9984903
187346260	187346283	2	+	27869803	HPAFII	viability after 31 days	GGACAGTCATGACTATAACCTGG	CALCRL	ENSG00000064989	0.8567412030560364	[240]	[142,355,NaN]	6	hSpCas9	negative selection	10067348
187352163	187352186	2	+	27869803	HPAFII	viability after 31 days	ATCTTTCCTTCAGGTCGCCATGG	CALCRL	ENSG00000064989	-0.24615878207260922	[113]	[74,30,NaN]	-2	hSpCas9	negative selection	10067349
187363378	187363401	2	+	27869803	HPAFII	viability after 31 days	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-1.4691915703451732	[73]	[14,14,NaN]	-7	hSpCas9	negative selection	10067350
187363396	187363419	2	-	27869803	HPAFII	viability after 31 days	CACTGCAGTGGCCAACAACCAGG	CALCRL	ENSG00000064989	0.00228805285498046	[458]	[112,415,NaN]	0	hSpCas9	negative selection	10067351
187380730	187380753	2	-	27869803	HPAFII	viability after 31 days	TGCTGGAACGATGTTGCAGCAGG	CALCRL	ENSG00000064989	-0.10636827550726793	[210]	[42,182,NaN]	0	hSpCas9	negative selection	10067352
187380466	187380489	2	-	28162770	P31FUJ	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.023855314142882333	[76]	[88]	0	hSpCas9	negative selection	10125245
187380479	187380502	2	+	28162770	P31FUJ	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.4820230479732408	[1089]	[1788]	5	hSpCas9	negative selection	10125246
187363378	187363401	2	+	28162770	P31FUJ	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.7585846652809134	[83]	[166]	8	hSpCas9	negative selection	10125247
187360649	187360672	2	-	28162770	P31FUJ	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	0.4987089596597196	[52]	[87]	5	hSpCas9	negative selection	10125248
187359068	187359091	2	+	28162770	P31FUJ	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.6576843108391308	[170]	[316]	7	hSpCas9	negative selection	10125249
187383269	187383292	2	-	28162770	P31FUJ	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-0.23671725441776192	[368]	[367]	-2	hSpCas9	negative selection	10125250
187383172	187383195	2	-	28162770	P31FUJ	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.7998024610175489	[174]	[357]	8	hSpCas9	negative selection	10125251
187363408	187363431	2	-	28162770	P31FUJ	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.03268368041351111	[489]	[588]	0	hSpCas9	negative selection	10125252
187352155	187352178	2	-	28162770	P31FUJ	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.6160680042501004	[366]	[660]	7	hSpCas9	negative selection	10125253
187359245	187359268	2	+	28162770	P31FUJ	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	-0.09912376918240935	[205]	[225]	-1	hSpCas9	negative selection	10125254
187380466	187380489	2	-	28162770	TF1	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10294611
187380479	187380502	2	+	28162770	TF1	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	NaN	[NaN]	[580]	1	hSpCas9	negative selection	10294612
187363378	187363401	2	+	28162770	TF1	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10294613
187360649	187360672	2	-	28162770	TF1	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	NaN	[NaN]	[93]	1	hSpCas9	negative selection	10294614
187359068	187359091	2	+	28162770	TF1	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	NaN	[NaN]	[322]	1	hSpCas9	negative selection	10294615
187383269	187383292	2	-	28162770	TF1	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	NaN	[NaN]	[426]	1	hSpCas9	negative selection	10294616
187383172	187383195	2	-	28162770	TF1	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10294617
187363408	187363431	2	-	28162770	TF1	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	NaN	[NaN]	[487]	1	hSpCas9	negative selection	10294618
187352155	187352178	2	-	28162770	TF1	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	NaN	[NaN]	[354]	1	hSpCas9	negative selection	10294619
187359245	187359268	2	+	28162770	TF1	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	NaN	[NaN]	[154]	1	hSpCas9	negative selection	10294620
187380466	187380489	2	-	28162770	SKM1	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.48994230829273466	[28]	[71]	5	hSpCas9	negative selection	10463977
187380479	187380502	2	+	28162770	SKM1	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.8762603668137166	[203]	[661]	8	hSpCas9	negative selection	10463978
187363378	187363401	2	+	28162770	SKM1	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.08503610385579918	[23]	[39]	0	hSpCas9	negative selection	10463979
187360649	187360672	2	-	28162770	SKM1	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	0.35857054761981555	[14]	[33]	3	hSpCas9	negative selection	10463980
187359068	187359091	2	+	28162770	SKM1	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.09814499428877976	[64]	[122]	0	hSpCas9	negative selection	10463981
187383269	187383292	2	-	28162770	SKM1	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-0.04888710038283395	[133]	[228]	0	hSpCas9	negative selection	10463982
187383172	187383195	2	-	28162770	SKM1	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.10399772053421746	[39]	[75]	1	hSpCas9	negative selection	10463983
187363408	187363431	2	-	28162770	SKM1	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.04620842942245318	[125]	[229]	0	hSpCas9	negative selection	10463984
187352155	187352178	2	-	28162770	SKM1	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	-0.35965848396480504	[89]	[123]	-3	hSpCas9	negative selection	10463985
187359245	187359268	2	+	28162770	SKM1	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	0.04589476597064929	[39]	[72]	0	hSpCas9	negative selection	10463986
187380466	187380489	2	-	28162770	SKM1	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.48994230829273466	[28]	[71]	5	hSpCas9	negative selection	10633343
187380479	187380502	2	+	28162770	SKM1	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.8762603668137166	[203]	[661]	8	hSpCas9	negative selection	10633344
187363378	187363401	2	+	28162770	SKM1	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.08503610385579918	[23]	[39]	0	hSpCas9	negative selection	10633345
187360649	187360672	2	-	28162770	SKM1	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	0.35857054761981555	[14]	[33]	3	hSpCas9	negative selection	10633346
187359068	187359091	2	+	28162770	SKM1	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.09814499428877976	[64]	[122]	0	hSpCas9	negative selection	10633347
187383269	187383292	2	-	28162770	SKM1	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-0.04888710038283395	[133]	[228]	0	hSpCas9	negative selection	10633348
187383172	187383195	2	-	28162770	SKM1	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.10399772053421746	[39]	[75]	1	hSpCas9	negative selection	10633349
187363408	187363431	2	-	28162770	SKM1	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.04620842942245318	[125]	[229]	0	hSpCas9	negative selection	10633350
187352155	187352178	2	-	28162770	SKM1	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	-0.35965848396480504	[89]	[123]	-3	hSpCas9	negative selection	10633351
187359245	187359268	2	+	28162770	SKM1	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	0.04589476597064929	[39]	[72]	0	hSpCas9	negative selection	10633352
187380466	187380489	2	-	28162770	PL21	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.5735845296870036	[105]	[30]	-4	hSpCas9	negative selection	10802709
187380479	187380502	2	+	28162770	PL21	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.5878697677724285	[719]	[470]	5	hSpCas9	negative selection	10802710
187363378	187363401	2	+	28162770	PL21	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	1.1371298169635196	[116]	[111]	8	hSpCas9	negative selection	10802711
187360649	187360672	2	-	28162770	PL21	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	-0.022252806847127715	[76]	[32]	0	hSpCas9	negative selection	10802712
187359068	187359091	2	+	28162770	PL21	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.9474968145021221	[248]	[208]	7	hSpCas9	negative selection	10802713
187383269	187383292	2	-	28162770	PL21	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-0.2828746786055305	[477]	[170]	-2	hSpCas9	negative selection	10802714
187383172	187383195	2	-	28162770	PL21	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	-1.3062130515354695	[124]	[21]	-7	hSpCas9	negative selection	10802715
187363408	187363431	2	-	28162770	PL21	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	-0.3132696252068021	[353]	[123]	-2	hSpCas9	negative selection	10802716
187352155	187352178	2	-	28162770	PL21	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.6795363595645422	[273]	[190]	6	hSpCas9	negative selection	10802717
187359245	187359268	2	+	28162770	PL21	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	-0.20321607974188832	[163]	[61]	-1	hSpCas9	negative selection	10802718
187380466	187380489	2	-	28162770	P31FUJ	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.023855314142882333	[76]	[88]	0	hSpCas9	negative selection	10972075
187380479	187380502	2	+	28162770	P31FUJ	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.4820230479732408	[1089]	[1788]	5	hSpCas9	negative selection	10972076
187363378	187363401	2	+	28162770	P31FUJ	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.7585846652809134	[83]	[166]	8	hSpCas9	negative selection	10972077
187360649	187360672	2	-	28162770	P31FUJ	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	0.4987089596597196	[52]	[87]	5	hSpCas9	negative selection	10972078
187359068	187359091	2	+	28162770	P31FUJ	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.6576843108391308	[170]	[316]	7	hSpCas9	negative selection	10972079
187383269	187383292	2	-	28162770	P31FUJ	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	-0.23671725441776192	[368]	[367]	-2	hSpCas9	negative selection	10972080
187383172	187383195	2	-	28162770	P31FUJ	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.7998024610175489	[174]	[357]	8	hSpCas9	negative selection	10972081
187363408	187363431	2	-	28162770	P31FUJ	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.03268368041351111	[489]	[588]	0	hSpCas9	negative selection	10972082
187352155	187352178	2	-	28162770	P31FUJ	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.6160680042501004	[366]	[660]	7	hSpCas9	negative selection	10972083
187359245	187359268	2	+	28162770	P31FUJ	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	-0.09912376918240935	[205]	[225]	-1	hSpCas9	negative selection	10972084
187380466	187380489	2	-	28162770	OCIAML5	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.14793342913600305	[82]	[165]	1	hSpCas9	negative selection	11141441
187380479	187380502	2	+	28162770	OCIAML5	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.6290601188726193	[527]	[1473]	5	hSpCas9	negative selection	11141442
187363378	187363401	2	+	28162770	OCIAML5	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.5415972776222798	[50]	[133]	5	hSpCas9	negative selection	11141443
187360649	187360672	2	-	28162770	OCIAML5	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	1.2791779624142556	[20]	[91]	9	hSpCas9	negative selection	11141444
187359068	187359091	2	+	28162770	OCIAML5	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.1824218055212934	[123]	[253]	1	hSpCas9	negative selection	11141445
187383269	187383292	2	-	28162770	OCIAML5	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.4001204527328044	[266]	[635]	3	hSpCas9	negative selection	11141446
187383172	187383195	2	-	28162770	OCIAML5	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	-1.1611706253937757	[139]	[112]	-6	hSpCas9	negative selection	11141447
187363408	187363431	2	-	28162770	OCIAML5	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	-0.06101346113549333	[355]	[615]	0	hSpCas9	negative selection	11141448
187352155	187352178	2	-	28162770	OCIAML5	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.5428907337874675	[207]	[546]	5	hSpCas9	negative selection	11141449
187359245	187359268	2	+	28162770	OCIAML5	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	0.17424470625185018	[162]	[331]	1	hSpCas9	negative selection	11141450
187380466	187380489	2	-	28162770	EOL1	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	1.0247119334959665	[152]	[163]	8	hSpCas9	negative selection	11310807
187380479	187380502	2	+	28162770	EOL1	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.4127891918945561	[950]	[666]	4	hSpCas9	negative selection	11310808
187363378	187363401	2	+	28162770	EOL1	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.25996810278601035	[148]	[93]	2	hSpCas9	negative selection	11310809
187360649	187360672	2	-	28162770	EOL1	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	-0.7510172779315281	[114]	[35]	-5	hSpCas9	negative selection	11310810
187359068	187359091	2	+	28162770	EOL1	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	1.1433823734937933	[347]	[404]	8	hSpCas9	negative selection	11310811
187383269	187383292	2	-	28162770	EOL1	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.27883123977028235	[775]	[495]	2	hSpCas9	negative selection	11310812
187383172	187383195	2	-	28162770	EOL1	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.377059976268041	[132]	[90]	3	hSpCas9	negative selection	11310813
187363408	187363431	2	-	28162770	EOL1	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.8916558900131598	[487]	[476]	7	hSpCas9	negative selection	11310814
187352155	187352178	2	-	28162770	EOL1	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.4049390088434781	[409]	[285]	3	hSpCas9	negative selection	11310815
187359245	187359268	2	+	28162770	EOL1	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	-0.47462332224928827	[210]	[79]	-4	hSpCas9	negative selection	11310816
187380466	187380489	2	-	28162770	MOLM13	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.3773770886391363	[147]	[138]	2	hSpCas9	negative selection	11480173
187380479	187380502	2	+	28162770	MOLM13	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.4033405337186535	[1096]	[1048]	3	hSpCas9	negative selection	11480174
187363378	187363401	2	+	28162770	MOLM13	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.38300048395806585	[139]	[131]	3	hSpCas9	negative selection	11480175
187360649	187360672	2	-	28162770	MOLM13	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	-0.5046298820333142	[103]	[52]	-3	hSpCas9	negative selection	11480176
187359068	187359091	2	+	28162770	MOLM13	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	1.278228162041004	[344]	[604]	8	hSpCas9	negative selection	11480177
187383269	187383292	2	-	28162770	MOLM13	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	1.2446455615166236	[564]	[967]	8	hSpCas9	negative selection	11480178
187383172	187383195	2	-	28162770	MOLM13	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.005098750817366993	[214]	[155]	0	hSpCas9	negative selection	11480179
187363408	187363431	2	-	28162770	MOLM13	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	-0.1892951570942354	[767]	[486]	-1	hSpCas9	negative selection	11480180
187352155	187352178	2	-	28162770	MOLM13	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.7492571131074771	[403]	[490]	5	hSpCas9	negative selection	11480181
187359245	187359268	2	+	28162770	MOLM13	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	0.9824625543743373	[195]	[279]	7	hSpCas9	negative selection	11480182
187380466	187380489	2	-	28162770	HEL	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.9745823957528019	[115]	[145]	8	hSpCas9	negative selection	11649539
187380479	187380502	2	+	28162770	HEL	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.37970442616656297	[905]	[754]	3	hSpCas9	negative selection	11649540
187363378	187363401	2	+	28162770	HEL	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.3197864625809804	[151]	[77]	-2	hSpCas9	negative selection	11649541
187360649	187360672	2	-	28162770	HEL	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	-0.001117357774367611	[124]	[79]	0	hSpCas9	negative selection	11649542
187359068	187359091	2	+	28162770	HEL	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	1.0546770926203142	[232]	[309]	8	hSpCas9	negative selection	11649543
187383269	187383292	2	-	28162770	HEL	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.6963989651599584	[474]	[492]	6	hSpCas9	negative selection	11649544
187383172	187383195	2	-	28162770	HEL	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	1.0035559402813141	[182]	[234]	8	hSpCas9	negative selection	11649545
187363408	187363431	2	-	28162770	HEL	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.3693819547987016	[532]	[440]	3	hSpCas9	negative selection	11649546
187352155	187352178	2	-	28162770	HEL	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	-0.6791892628870055	[299]	[119]	-4	hSpCas9	negative selection	11649547
187359245	187359268	2	+	28162770	HEL	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	1.298090660612911	[159]	[251]	9	hSpCas9	negative selection	11649548
187380466	187380489	2	-	28162770	MV411	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.6100076301674837	[90]	[116]	5	hSpCas9	negative selection	11818905
187380479	187380502	2	+	28162770	MV411	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.7138604363285306	[654]	[904]	6	hSpCas9	negative selection	11818906
187363378	187363401	2	+	28162770	MV411	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	1.0082498869033492	[71]	[121]	8	hSpCas9	negative selection	11818907
187360649	187360672	2	-	28162770	MV411	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	1.0993389117936414	[40]	[73]	8	hSpCas9	negative selection	11818908
187359068	187359091	2	+	28162770	MV411	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	1.7627945840180648	[183]	[525]	9	hSpCas9	negative selection	11818909
187383269	187383292	2	-	28162770	MV411	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.3010008271981839	[422]	[438]	2	hSpCas9	negative selection	11818910
187383172	187383195	2	-	28162770	MV411	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.5551049525449682	[121]	[150]	5	hSpCas9	negative selection	11818911
187363408	187363431	2	-	28162770	MV411	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	1.1739236264665307	[311]	[592]	9	hSpCas9	negative selection	11818912
187352155	187352178	2	-	28162770	MV411	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.3094985189150268	[272]	[284]	2	hSpCas9	negative selection	11818913
187359245	187359268	2	+	28162770	MV411	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	0.4065040367503938	[162]	[181]	3	hSpCas9	negative selection	11818914
187380466	187380489	2	-	28162770	MONOMAC1	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	0.7098537485489648	[39]	[74]	6	hSpCas9	negative selection	11988271
187380479	187380502	2	+	28162770	MONOMAC1	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.09918686505620933	[486]	[597]	1	hSpCas9	negative selection	11988272
187363378	187363401	2	+	28162770	MONOMAC1	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.4120497380304039	[64]	[55]	-4	hSpCas9	negative selection	11988273
187360649	187360672	2	-	28162770	MONOMAC1	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	-0.24143096641800743	[32]	[31]	-2	hSpCas9	negative selection	11988274
187359068	187359091	2	+	28162770	MONOMAC1	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.25731357624411644	[180]	[247]	2	hSpCas9	negative selection	11988275
187383269	187383292	2	-	28162770	MONOMAC1	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	1.0213402779446734	[256]	[597]	8	hSpCas9	negative selection	11988276
187383172	187383195	2	-	28162770	MONOMAC1	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.6774322708565875	[71]	[131]	6	hSpCas9	negative selection	11988277
187363408	187363431	2	-	28162770	MONOMAC1	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.030498877552853965	[239]	[280]	0	hSpCas9	negative selection	11988278
187352155	187352178	2	-	28162770	MONOMAC1	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.8159410069386563	[165]	[334]	7	hSpCas9	negative selection	11988279
187359245	187359268	2	+	28162770	MONOMAC1	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	-0.559606926444262	[107]	[83]	-5	hSpCas9	negative selection	11988280
187380466	187380489	2	-	28162770	OCIAML2	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-1.0873011856906554	[22]	[59]	-6	hSpCas9	negative selection	12157637
187380479	187380502	2	+	28162770	OCIAML2	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.7368122546283151	[96]	[895]	7	hSpCas9	negative selection	12157638
187363378	187363401	2	+	28162770	OCIAML2	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	0.8147723936200872	[15]	[155]	7	hSpCas9	negative selection	12157639
187360649	187360672	2	-	28162770	OCIAML2	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	0.3524924126737594	[12]	[91]	3	hSpCas9	negative selection	12157640
187359068	187359091	2	+	28162770	OCIAML2	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.4050760651808316	[52]	[388]	4	hSpCas9	negative selection	12157641
187383269	187383292	2	-	28162770	OCIAML2	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.5899117166928896	[69]	[583]	6	hSpCas9	negative selection	12157642
187383172	187383195	2	-	28162770	OCIAML2	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	1.1538610396656326	[14]	[184]	9	hSpCas9	negative selection	12157643
187363408	187363431	2	-	28162770	OCIAML2	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.8538722133090274	[55]	[560]	8	hSpCas9	negative selection	12157644
187352155	187352178	2	-	28162770	OCIAML2	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	0.44393469825177834	[49]	[376]	4	hSpCas9	negative selection	12157645
187359245	187359268	2	+	28162770	OCIAML2	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	1.3521003227023587	[19]	[282]	9	hSpCas9	negative selection	12157646
187380466	187380489	2	-	28162770	OCIAML3	viability	TAACACCCACGAGAAAGTGAAGG	CALCRL	ENSG00000064989	-0.057954740083953404	[29]	[86]	0	hSpCas9	negative selection	12327003
187380479	187380502	2	+	28162770	OCIAML3	viability	GTGGGTGTTAACATTACACTGGG	CALCRL	ENSG00000064989	0.6492635106882005	[195]	[927]	6	hSpCas9	negative selection	12327004
187363378	187363401	2	+	28162770	OCIAML3	viability	GATTTGTGGCTACTAAGGCCTGG	CALCRL	ENSG00000064989	-0.3272210996292617	[31]	[76]	-3	hSpCas9	negative selection	12327005
187360649	187360672	2	-	28162770	OCIAML3	viability	CCTACACACACTCATTGTGGTGG	CALCRL	ENSG00000064989	0.9689285540669941	[10]	[64]	8	hSpCas9	negative selection	12327006
187359068	187359091	2	+	28162770	OCIAML3	viability	AAGCAGCACAAATTGGGCCATGG	CALCRL	ENSG00000064989	0.48128048698007403	[55]	[235]	4	hSpCas9	negative selection	12327007
187383269	187383292	2	-	28162770	OCIAML3	viability	AGAATTAGAAGAGAGTCCTGAGG	CALCRL	ENSG00000064989	0.3591981481968958	[93]	[363]	3	hSpCas9	negative selection	12327008
187383172	187383195	2	-	28162770	OCIAML3	viability	GACCCCATTCAACAAGCAGAAGG	CALCRL	ENSG00000064989	0.8830395212301057	[36]	[205]	7	hSpCas9	negative selection	12327009
187363408	187363431	2	-	28162770	OCIAML3	viability	AATCATTCACCTCACTGCAGTGG	CALCRL	ENSG00000064989	0.020101206056509446	[97]	[299]	0	hSpCas9	negative selection	12327010
187352155	187352178	2	-	28162770	OCIAML3	viability	ACCTGAAGGAAAGATTGCAGAGG	CALCRL	ENSG00000064989	-0.562643469414828	[90]	[185]	-4	hSpCas9	negative selection	12327011
187359245	187359268	2	+	28162770	OCIAML3	viability	TGTATACAAGCAGGAATCAGTGG	CALCRL	ENSG00000064989	0.5997641030725169	[39]	[182]	5	hSpCas9	negative selection	12327012