| 546991 | 547014 | 16 | - | 26472758 | Jiyoye | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 6.361371691892748 | [0] | [61] | 9 | hSpCas9 | negative selection | 23270 | 546991 | 547014 | 16 | - | 26472758 | KBM7 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | -0.18132888552555348 | [155,67] | [57,32] | -2 | hSpCas9 | negative selection | 214388 | 546991 | 547014 | 16 | - | 26472758 | Raji | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 0.5224210346524436 | [11] | [3] | 5 | hSpCas9 | negative selection | 405506 | 546991 | 547014 | 16 | - | 26472758 | K562 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 0.26627816163018636 | [130] | [132] | 2 | hSpCas9 | negative selection | 596624 | 531305 | 531328 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | ATTTGGGAGGCTGAGGCAGGAAG | CAPN15 | ENSG00000103326 | 1.0311422578945828 | [46,428] | [158,53] | 4 | dCas9-VP64 | positive selection | 2400087 | 527699 | 527722 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCCTGTGGGAGCCGTAGTCCGGG | CAPN15 | ENSG00000103326 | 0.32937436535714343 | [23,101] | [29,3] | 1 | dCas9-VP64 | positive selection | 2438370 | 531221 | 531244 | CHR_HSCHR16_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCCTGTGGGAGCCGTAGTCCGGG | CAPN15 | ENSG00000282214 | 0.32937436535714343 | [23,101] | [29,3] | 1 | dCas9-VP64 | positive selection | 2438371 | 531239 | 531262 | CHR_HSCHR16_CTG2 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGCGCTGTGAATCGCGCGCCCGG | CAPN15 | ENSG00000282214 | 0.4435493196354503 | [18,37] | [6,8] | 2 | dCas9-VP64 | positive selection | 2438372 | 527717 | 527740 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGCGCTGTGAATCGCGCGCCCGG | CAPN15 | ENSG00000103326 | 0.4435493196354503 | [18,37] | [6,8] | 2 | dCas9-VP64 | positive selection | 2438373 | 536446 | 536469 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGAGTCTCGCTCTGTCGCCCCGG | CAPN15 | ENSG00000103326 | -0.5315818005101806 | [14,129] | [5,15] | -3 | dCas9-VP64 | positive selection | 2444239 | 531305 | 531328 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | ATTTGGGAGGCTGAGGCAGGAAG | CAPN15 | ENSG00000103326 | 0.6350691816100226 | [174,241] | [44,161] | 5 | dCas9-VP64 | positive selection | 2495342 | 527699 | 527722 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCCTGTGGGAGCCGTAGTCCGGG | CAPN15 | ENSG00000103326 | -0.8290158066266011 | [184,88] | [33,15] | -7 | dCas9-VP64 | positive selection | 2533625 | 531221 | 531244 | CHR_HSCHR16_CTG2 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCCTGTGGGAGCCGTAGTCCGGG | CAPN15 | ENSG00000282214 | -0.8290158066266011 | [184,88] | [33,15] | -7 | dCas9-VP64 | positive selection | 2533626 | 531239 | 531262 | CHR_HSCHR16_CTG2 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGCGCTGTGAATCGCGCGCCCGG | CAPN15 | ENSG00000282214 | -0.6197501553090186 | [90,17] | [15,6] | -6 | dCas9-VP64 | positive selection | 2533627 | 527717 | 527740 | 16 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGCGCTGTGAATCGCGCGCCCGG | CAPN15 | ENSG00000103326 | -0.6197501553090186 | [90,17] | [15,6] | -6 | dCas9-VP64 | positive selection | 2533628 | 536446 | 536469 | 16 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGAGTCTCGCTCTGTCGCCCCGG | CAPN15 | ENSG00000103326 | 0.35722745049512583 | [51,32] | [17,15] | 3 | dCas9-VP64 | positive selection | 2539494 | 546899 | 546922 | 16 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCGCCAGTGCTCCATCTGCGAGG | CAPN15 | ENSG00000103326 | 0.10020741971157304 | [2,3] | [3,2] | 2 | hSpCas9 | positive selection | 2976227 | 546899 | 546922 | 16 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCGCCAGTGCTCCATCTGCGAGG | CAPN15 | ENSG00000103326 | 0.9218629759270462 | [2,2] | [3,3] | 9 | hSpCas9 | positive selection | 3044085 | 546898 | 546921 | 16 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GCGCCAGTGCTCCATCTGCGAGG | CAPN15 | ENSG00000103326 | 0.589220161184289 | [] | [] | 2 | hSpCas9 | negative selection | 3412504 | 546898 | 546921 | 16 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCGCCAGTGCTCCATCTGCGAGG | CAPN15 | ENSG00000103326 | 4.39161741703131 | [] | [] | 7 | hSpCas9 | negative selection | 3488001 | 547112 | 547135 | 16 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCCATCCTGGGGGAGCCCAAGGG | CAPN15 | ENSG00000103326 | 4.43304183846963 | [] | [] | 7 | hSpCas9 | negative selection | 3488002 | 546898 | 546921 | 16 | + | 26780180 | A375 | viability (Avana lentiGuide) | GCGCCAGTGCTCCATCTGCGAGG | CAPN15 | ENSG00000103326 | 1.78405301128256 | [] | [] | 2 | hSpCas9 | negative selection | 3596660 | 547112 | 547135 | 16 | + | 26780180 | A375 | viability (Avana lentiGuide) | GCCATCCTGGGGGAGCCCAAGGG | CAPN15 | ENSG00000103326 | -0.259926219133451 | [] | [] | 0 | hSpCas9 | negative selection | 3596661 | 546898 | 546921 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCGCCAGTGCTCCATCTGCGAGG | CAPN15 | ENSG00000103326 | -0.024909568257691972 | [3] | [4,3] | 0 | hSpCas9 | positive selection | 3705319 | 547112 | 547135 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCCATCCTGGGGGAGCCCAAGGG | CAPN15 | ENSG00000103326 | 0.1827068997928331 | [4] | [5,4] | 5 | hSpCas9 | positive selection | 3705320 | 546898 | 546921 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCGCCAGTGCTCCATCTGCGAGG | CAPN15 | ENSG00000103326 | -0.8759355298923616 | [5] | [1,1] | -8 | hSpCas9 | positive selection | 3813926 | 547112 | 547135 | 16 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCCATCCTGGGGGAGCCCAAGGG | CAPN15 | ENSG00000103326 | -0.39438010425701847 | [5] | [2,3] | -5 | hSpCas9 | positive selection | 3813927 | 546843 | 546866 | 16 | - | 26780180 | A375 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 1.23695591396288 | [] | [] | 6 | hSpCas9 | negative selection | 3922221 | 536049 | 536072 | 16 | - | 26780180 | A375 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.849292075863425 | [] | [] | 3 | hSpCas9 | negative selection | 3922222 | 536080 | 536103 | 16 | - | 26780180 | A375 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | 1.06610767241115 | [] | [] | 5 | hSpCas9 | negative selection | 3922223 | 546843 | 546866 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.890051783160308 | [] | [] | 4 | hSpCas9 | negative selection | 4030187 | 536049 | 536072 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.980130686871737 | [] | [] | 4 | hSpCas9 | negative selection | 4030188 | 536080 | 536103 | 16 | - | 26780180 | HT29 | viability (GeCKOv2 library) | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | 0.75979299065908 | [] | [] | 3 | hSpCas9 | negative selection | 4030189 | 546843 | 546866 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.002377892387463082 | [2] | [1,1] | 0 | hSpCas9 | positive selection | 4299797 | 536080 | 536103 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | 0.05771619808498166 | [3] | [2,2] | 1 | hSpCas9 | positive selection | 4364050 | 536049 | 536072 | 16 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.09228076367441965 | [2] | [1,1] | 1 | hSpCas9 | positive selection | 4364051 | 527776 | 527799 | 16 | + | 27661255 | K562 | viability | GGCCGGGCGCTACGCTACGAAGG | CAPN15 | ENSG00000103326 | 0.14147258726669826 | [605,674] | [586,542] | 5 | dCas9-KRAB | negative selection | 5468036 | 527909 | 527932 | 16 | + | 27661255 | K562 | viability | GGGGCCCCGCCGCTCTCCGGAGG | CAPN15 | ENSG00000103326 | 0.14148738520689247 | [520,595] | [525,460] | 5 | dCas9-KRAB | negative selection | 5468037 | 528150 | 528173 | 16 | + | 27661255 | K562 | viability | GCGCGCCGGGCTCCGAGCCAGGG | CAPN15 | ENSG00000103326 | 0.11390881032325106 | [588,557] | [553,446] | 4 | dCas9-KRAB | negative selection | 5468038 | 528244 | 528267 | 16 | + | 27661255 | K562 | viability | GGCTGGGCGATGCTTCGCAGAGG | CAPN15 | ENSG00000103326 | 0.17386121998162624 | [577,673] | [649,487] | 6 | dCas9-KRAB | negative selection | 5468039 | 546843 | 546866 | 16 | - | 27260156 | BXPC3 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.04875633208618846 | [291] | [329,311,190,344] | -1 | hSpCas9 | negative selection | 5572257 | 536080 | 536103 | 16 | - | 27260156 | BXPC3 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.14800665390551068 | [611] | [437,579,684,625] | -3 | hSpCas9 | negative selection | 5636510 | 536049 | 536072 | 16 | - | 27260156 | BXPC3 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.12066214535515918 | [248] | [240,201,200,323] | -3 | hSpCas9 | negative selection | 5636511 | 546843 | 546866 | 16 | - | 27260156 | A673 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.20560291063645564 | [291] | [424,430,380,379] | 5 | hSpCas9 | negative selection | 5693508 | 536080 | 536103 | 16 | - | 27260156 | A673 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.07636778859471904 | [611] | [811,577,666,748] | -2 | hSpCas9 | negative selection | 5757761 | 536049 | 536072 | 16 | - | 27260156 | A673 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.0517302166172261 | [248] | [268,311,282,373] | 1 | hSpCas9 | negative selection | 5757762 | 546843 | 546866 | 16 | - | 27260156 | A375 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.35849349643604134 | [291] | [199,333,345,199] | -5 | hSpCas9 | negative selection | 5814759 | 536080 | 536103 | 16 | - | 27260156 | A375 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.3304499040585825 | [611] | [514,621,473,656] | -5 | hSpCas9 | negative selection | 5879012 | 536049 | 536072 | 16 | - | 27260156 | A375 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.6591446677410008 | [248] | [147,301,107,192] | -7 | hSpCas9 | negative selection | 5879013 | 546843 | 546866 | 16 | - | 27260156 | COLO741 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.23056359194343068 | [291] | [507,468,347] | 5 | hSpCas9 | negative selection | 5936010 | 536080 | 536103 | 16 | - | 27260156 | COLO741 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | 0.0908739811763149 | [611] | [931,910,673] | 2 | hSpCas9 | negative selection | 6000263 | 536049 | 536072 | 16 | - | 27260156 | COLO741 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.2027090819728984 | [248] | [361,255,221] | -4 | hSpCas9 | negative selection | 6000264 | 546843 | 546866 | 16 | - | 27260156 | CAL120 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.197410941232659 | [291] | [364,287,304] | -3 | hSpCas9 | negative selection | 6057261 | 536080 | 536103 | 16 | - | 27260156 | CAL120 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.3208431683605219 | [611] | [901,536,436] | -5 | hSpCas9 | negative selection | 6121514 | 536049 | 536072 | 16 | - | 27260156 | CAL120 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.5542653494273697 | [248] | [477,476,413] | 8 | hSpCas9 | negative selection | 6121515 | 546843 | 546866 | 16 | - | 27260156 | CADOES1 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.09259323337109937 | [291] | [224,240,216,338] | -1 | hSpCas9 | negative selection | 6178512 | 536080 | 536103 | 16 | - | 27260156 | CADOES1 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.20348964961747454 | [611] | [421,465,527,563] | -4 | hSpCas9 | negative selection | 6242765 | 536049 | 536072 | 16 | - | 27260156 | CADOES1 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.10828536292196034 | [248] | [214,202,343,235] | 2 | hSpCas9 | negative selection | 6242766 | 546843 | 546866 | 16 | - | 27260156 | EWS502 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.0480565685452331 | [291] | [274,284,322,407] | 0 | hSpCas9 | negative selection | 6299763 | 536080 | 536103 | 16 | - | 27260156 | EWS502 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | 0.03985482423827186 | [611] | [490,686,612,908] | 0 | hSpCas9 | negative selection | 6364016 | 536049 | 536072 | 16 | - | 27260156 | EWS502 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.33891665711390107 | [248] | [345,407,241,330] | 6 | hSpCas9 | negative selection | 6364017 | 546843 | 546866 | 16 | - | 27260156 | EW8 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.019626648084939524 | [291] | [353,175,228,187] | 0 | hSpCas9 | negative selection | 6421014 | 536080 | 536103 | 16 | - | 27260156 | EW8 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.03208979428276082 | [611] | [624,465,427,444] | 0 | hSpCas9 | negative selection | 6485267 | 536049 | 536072 | 16 | - | 27260156 | EW8 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.07288456880041139 | [248] | [313,180,173,196] | 1 | hSpCas9 | negative selection | 6485268 | 546843 | 546866 | 16 | - | 27260156 | CORL105 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.22407080221780296 | [291] | [194,300,300,370] | -4 | hSpCas9 | negative selection | 6542265 | 536080 | 536103 | 16 | - | 27260156 | CORL105 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.07853447457799106 | [611] | [551,652,732,779] | -1 | hSpCas9 | negative selection | 6606518 | 536049 | 536072 | 16 | - | 27260156 | CORL105 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.3464426328154765 | [248] | [244,262,234,174] | -6 | hSpCas9 | negative selection | 6606519 | 546843 | 546866 | 16 | - | 27260156 | HS294T | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.3833432230354277 | [291] | [121,112,245,103] | 5 | hSpCas9 | negative selection | 6663516 | 536080 | 536103 | 16 | - | 27260156 | HS294T | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.20455766820636279 | [611] | [185,157,200,293] | -3 | hSpCas9 | negative selection | 6727769 | 536049 | 536072 | 16 | - | 27260156 | HS294T | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.20339569631190624 | [248] | [76,94,75,86] | -3 | hSpCas9 | negative selection | 6727770 | 546843 | 546866 | 16 | - | 27260156 | HCC44 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.4154773564889986 | [291] | [533,409,395,423] | 6 | hSpCas9 | negative selection | 6784767 | 536080 | 536103 | 16 | - | 27260156 | HCC44 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | 0.06157037001330956 | [611] | [711,492,924,816] | 0 | hSpCas9 | negative selection | 6849020 | 536049 | 536072 | 16 | - | 27260156 | HCC44 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.07596724764694696 | [248] | [416,381,208,164] | 1 | hSpCas9 | negative selection | 6849021 | 546843 | 546866 | 16 | - | 27260156 | G402 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.38090726726757507 | [291] | [350,341,362,62] | -5 | hSpCas9 | negative selection | 6906018 | 536080 | 536103 | 16 | - | 27260156 | G402 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.30905115636496827 | [611] | [508,923,465,518] | -4 | hSpCas9 | negative selection | 6970271 | 536049 | 536072 | 16 | - | 27260156 | G402 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.3564089902911901 | [248] | [287,347,333,558] | 4 | hSpCas9 | negative selection | 6970272 | 546843 | 546866 | 16 | - | 27260156 | L33 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.04238484279320498 | [291] | [266,165,180,243] | 1 | hSpCas9 | negative selection | 7027269 | 536080 | 536103 | 16 | - | 27260156 | L33 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.13464483839787175 | [611] | [435,256,323,652] | -3 | hSpCas9 | negative selection | 7091522 | 536049 | 536072 | 16 | - | 27260156 | L33 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.19741948454360092 | [248] | [155,85,123,305] | -4 | hSpCas9 | negative selection | 7091523 | 546843 | 546866 | 16 | - | 27260156 | K562 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.3388133909916755 | [291] | [326,228,144,136] | -4 | hSpCas9 | negative selection | 7148520 | 536080 | 536103 | 16 | - | 27260156 | K562 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.11942353861015698 | [611] | [401,1039,386,221] | -1 | hSpCas9 | negative selection | 7212773 | 536049 | 536072 | 16 | - | 27260156 | K562 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.3952464925736511 | [248] | [63,259,225,122] | -5 | hSpCas9 | negative selection | 7212774 | 546843 | 546866 | 16 | - | 27260156 | HT29 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.08623148230369493 | [291] | [372,436,311,236] | -2 | hSpCas9 | negative selection | 7269771 | 536080 | 536103 | 16 | - | 27260156 | HT29 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.1261254197103825 | [611] | [771,756,621,594] | -3 | hSpCas9 | negative selection | 7334024 | 536049 | 536072 | 16 | - | 27260156 | HT29 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.17522129095065575 | [248] | [365,235,266,212] | -4 | hSpCas9 | negative selection | 7334025 | 546843 | 546866 | 16 | - | 27260156 | MHHES1 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.23240155081058028 | [291] | [387,483,515,202] | 4 | hSpCas9 | negative selection | 7391022 | 536080 | 536103 | 16 | - | 27260156 | MHHES1 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.11141649259862108 | [611] | [761,677,733,431] | -2 | hSpCas9 | negative selection | 7455275 | 536049 | 536072 | 16 | - | 27260156 | MHHES1 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.07041724821946205 | [248] | [443,154,347,240] | 1 | hSpCas9 | negative selection | 7455276 | 546843 | 546866 | 16 | - | 27260156 | MEWO | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.1936766882348705 | [291] | [412,253,289] | 4 | hSpCas9 | negative selection | 7512273 | 536080 | 536103 | 16 | - | 27260156 | MEWO | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | 0.09872587384263581 | [611] | [603,704,527] | 2 | hSpCas9 | negative selection | 7576526 | 536049 | 536072 | 16 | - | 27260156 | MEWO | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.03429431324959464 | [248] | [211,308,157] | 0 | hSpCas9 | negative selection | 7576527 | 546843 | 546866 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.22376999380436202 | [291] | [256,266,208,166] | -4 | hSpCas9 | negative selection | 7633524 | 536080 | 536103 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.3680078880605028 | [611] | [234,289,860,408] | -5 | hSpCas9 | negative selection | 7697777 | 536049 | 536072 | 16 | - | 27260156 | LNCAPCLONEFGC | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.10802039448221745 | [248] | [241,277,310,148] | 1 | hSpCas9 | negative selection | 7697778 | 546843 | 546866 | 16 | - | 27260156 | PANC0327 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.41101501312774147 | [291] | [131,135,345,168] | -5 | hSpCas9 | negative selection | 7754775 | 536080 | 536103 | 16 | - | 27260156 | PANC0327 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.5310295575157369 | [611] | [346,259,659,250] | -6 | hSpCas9 | negative selection | 7819028 | 536049 | 536072 | 16 | - | 27260156 | PANC0327 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.26793436427036277 | [248] | [265,86,204,195] | -4 | hSpCas9 | negative selection | 7819029 | 546843 | 546866 | 16 | - | 27260156 | NCIH2009 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.12531665295726613 | [291] | [422,325,382] | -2 | hSpCas9 | negative selection | 7876026 | 536080 | 536103 | 16 | - | 27260156 | NCIH2009 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.16895408807786427 | [611] | [956,607,756] | -2 | hSpCas9 | negative selection | 7940279 | 536049 | 536072 | 16 | - | 27260156 | NCIH2009 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.2380486658429034 | [248] | [638,322,314] | 3 | hSpCas9 | negative selection | 7940280 | 546843 | 546866 | 16 | - | 27260156 | NCIH1373 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.5048237626206062 | [291] | [278,175,173,81] | -5 | hSpCas9 | negative selection | 7997277 | 536080 | 536103 | 16 | - | 27260156 | NCIH1373 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.2008567669652195 | [611] | [658,787,543,96] | -2 | hSpCas9 | negative selection | 8061530 | 536049 | 536072 | 16 | - | 27260156 | NCIH1373 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.449683587976237 | [248] | [256,355,77,29] | -4 | hSpCas9 | negative selection | 8061531 | 546843 | 546866 | 16 | - | 27260156 | PATU8902 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.018174711314352443 | [291] | [358,608,210,532] | 0 | hSpCas9 | negative selection | 8118528 | 536080 | 536103 | 16 | - | 27260156 | PATU8902 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.35825766170153894 | [611] | [670,461,723,796] | -4 | hSpCas9 | negative selection | 8182781 | 536049 | 536072 | 16 | - | 27260156 | PATU8902 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.16089213705536098 | [248] | [248,136,256,649] | -2 | hSpCas9 | negative selection | 8182782 | 546843 | 546866 | 16 | - | 27260156 | PANC1 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.4057880523434114 | [291] | [254,240,127,145] | -6 | hSpCas9 | negative selection | 8239779 | 536080 | 536103 | 16 | - | 27260156 | PANC1 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.09485979589420046 | [611] | [415,625,617,353] | -1 | hSpCas9 | negative selection | 8304032 | 536049 | 536072 | 16 | - | 27260156 | PANC1 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.32616464132505973 | [248] | [137,306,140,128] | -5 | hSpCas9 | negative selection | 8304033 | 546843 | 546866 | 16 | - | 27260156 | PANC0813 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.1401688800134938 | [291] | [221,356,391,267] | -2 | hSpCas9 | negative selection | 8361030 | 536080 | 536103 | 16 | - | 27260156 | PANC0813 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.46996105104348684 | [611] | [622,614,483,370] | -6 | hSpCas9 | negative selection | 8425283 | 536049 | 536072 | 16 | - | 27260156 | PANC0813 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.4818719627754754 | [248] | [364,142,194,151] | -6 | hSpCas9 | negative selection | 8425284 | 546843 | 546866 | 16 | - | 27260156 | RDES | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.2280217392711612 | [291] | [278,192,293,399] | -4 | hSpCas9 | negative selection | 8482281 | 536080 | 536103 | 16 | - | 27260156 | RDES | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | 0.20930868166782418 | [611] | [643,678,1022,965] | 3 | hSpCas9 | negative selection | 8546534 | 536049 | 536072 | 16 | - | 27260156 | RDES | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.37685896984403133 | [248] | [433,293,435,293] | 6 | hSpCas9 | negative selection | 8546535 | 546843 | 546866 | 16 | - | 27260156 | PC3 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.07610890109186341 | [291] | [203,297,524,298] | 1 | hSpCas9 | negative selection | 8603532 | 536080 | 536103 | 16 | - | 27260156 | PC3 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.2262113551231272 | [611] | [254,674,844,501] | -5 | hSpCas9 | negative selection | 8667785 | 536049 | 536072 | 16 | - | 27260156 | PC3 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.10666379053722619 | [248] | [123,217,526,350] | 2 | hSpCas9 | negative selection | 8667786 | 546843 | 546866 | 16 | - | 27260156 | PATU8988T | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.35451865743965444 | [291] | [325,228,595,268] | 6 | hSpCas9 | negative selection | 8724783 | 536080 | 536103 | 16 | - | 27260156 | PATU8988T | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.22235406803630003 | [611] | [526,420,384,703] | -4 | hSpCas9 | negative selection | 8789036 | 536049 | 536072 | 16 | - | 27260156 | PATU8988T | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.030347534736650972 | [248] | [317,230,177,213] | 0 | hSpCas9 | negative selection | 8789037 | 546843 | 546866 | 16 | - | 27260156 | T47D | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.024283251809675943 | [291] | [359,321,327,328] | 0 | hSpCas9 | negative selection | 8846034 | 536080 | 536103 | 16 | - | 27260156 | T47D | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.25053682738606053 | [611] | [628,593,595,577] | -5 | hSpCas9 | negative selection | 8910287 | 536049 | 536072 | 16 | - | 27260156 | T47D | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.04278963960970028 | [248] | [340,315,274,260] | 0 | hSpCas9 | negative selection | 8910288 | 546843 | 546866 | 16 | - | 27260156 | SU8686 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.22170282946209907 | [291] | [226,228,226,324] | -4 | hSpCas9 | negative selection | 8967285 | 536080 | 536103 | 16 | - | 27260156 | SU8686 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.302817268138913 | [611] | [408,541,416,616] | -5 | hSpCas9 | negative selection | 9031538 | 536049 | 536072 | 16 | - | 27260156 | SU8686 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.028164378529977663 | [248] | [184,222,277,299] | 0 | hSpCas9 | negative selection | 9031539 | 546843 | 546866 | 16 | - | 27260156 | SKES1 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.14022686186118838 | [291] | [332,364,255,332] | 3 | hSpCas9 | negative selection | 9088536 | 536080 | 536103 | 16 | - | 27260156 | SKES1 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.06272962400444587 | [611] | [695,697,440,533] | -1 | hSpCas9 | negative selection | 9152789 | 536049 | 536072 | 16 | - | 27260156 | SKES1 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.0044872843926268 | [248] | [260,320,295,138] | 0 | hSpCas9 | negative selection | 9152790 | 546843 | 546866 | 16 | - | 27260156 | TOV112D | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.23181868564899788 | [291] | [342,199,177,269] | -4 | hSpCas9 | negative selection | 9209787 | 536080 | 536103 | 16 | - | 27260156 | TOV112D | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | 0.09189815862422857 | [611] | [678,819,532,623] | 1 | hSpCas9 | negative selection | 9274040 | 536049 | 536072 | 16 | - | 27260156 | TOV112D | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.3477976131425895 | [248] | [334,472,264,237] | 6 | hSpCas9 | negative selection | 9274041 | 546843 | 546866 | 16 | - | 27260156 | TC71 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | 0.04289046537441432 | [291] | [337,317,358,269] | 1 | hSpCas9 | negative selection | 9331038 | 536080 | 536103 | 16 | - | 27260156 | TC71 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.09429516185782999 | [611] | [657,668,470,666] | -2 | hSpCas9 | negative selection | 9395291 | 536049 | 536072 | 16 | - | 27260156 | TC71 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | 0.18480061848039175 | [248] | [245,296,333,338] | 4 | hSpCas9 | negative selection | 9395292 | 546843 | 546866 | 16 | - | 27260156 | TC32 | viability | ACAGGACCACTCTCCGACCGTGG | CAPN15 | ENSG00000103326 | -0.13056186660425695 | [291] | [337,155,292,230] | -2 | hSpCas9 | negative selection | 9452289 | 536080 | 536103 | 16 | - | 27260156 | TC32 | viability | ACGTGAATCACCCAGTGCAGTGG | CAPN15 | ENSG00000103326 | -0.046424760934859144 | [611] | [546,473,632,585] | -1 | hSpCas9 | negative selection | 9516542 | 536049 | 536072 | 16 | - | 27260156 | TC32 | viability | ACGCAGGTCAGGTCAGTCCGTGG | CAPN15 | ENSG00000103326 | -0.2401477055932345 | [248] | [154,132,220,312] | -4 | hSpCas9 | negative selection | 9516543 | 546991 | 547014 | 16 | - | 28162770 | P31FUJ | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 0.5490176255360881 | [56] | [97] | 6 | hSpCas9 | negative selection | 10125716 | 546991 | 547014 | 16 | - | 28162770 | TF1 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | NaN | [NaN] | [95] | 1 | hSpCas9 | negative selection | 10295082 | 546991 | 547014 | 16 | - | 28162770 | SKM1 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | -0.0850361038557994 | [17] | [29] | 0 | hSpCas9 | negative selection | 10464448 | 546991 | 547014 | 16 | - | 28162770 | SKM1 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | -0.0850361038557994 | [17] | [29] | 0 | hSpCas9 | negative selection | 10633814 | 546991 | 547014 | 16 | - | 28162770 | PL21 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 0.6976392739601369 | [33] | [23] | 6 | hSpCas9 | negative selection | 10803180 | 546991 | 547014 | 16 | - | 28162770 | P31FUJ | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 0.5490176255360881 | [56] | [97] | 6 | hSpCas9 | negative selection | 10972546 | 546991 | 547014 | 16 | - | 28162770 | OCIAML5 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 1.5229728604829278 | [15] | [82] | 9 | hSpCas9 | negative selection | 11141912 | 546991 | 547014 | 16 | - | 28162770 | EOL1 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | -0.0014516469856886705 | [75] | [39] | 0 | hSpCas9 | negative selection | 11311278 | 546991 | 547014 | 16 | - | 28162770 | MOLM13 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 0.637814382986891 | [47] | [53] | 5 | hSpCas9 | negative selection | 11480644 | 546991 | 547014 | 16 | - | 28162770 | HEL | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 1.1402384914711736 | [67] | [95] | 8 | hSpCas9 | negative selection | 11650010 | 546991 | 547014 | 16 | - | 28162770 | MV411 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | 0.8621473948979836 | [31] | [48] | 7 | hSpCas9 | negative selection | 11819376 | 546991 | 547014 | 16 | - | 28162770 | MONOMAC1 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | -1.0450337536145038 | [26] | [14] | -7 | hSpCas9 | negative selection | 11988742 | 546991 | 547014 | 16 | - | 28162770 | OCIAML2 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | -0.31308854825568133 | [12] | [57] | -3 | hSpCas9 | negative selection | 12158108 | 546991 | 547014 | 16 | - | 28162770 | OCIAML3 | viability | GGAAGTTGCGGAAGGTGCAGCGG | CAPN15 | ENSG00000103326 | -1.387556762856737 | [12] | [14] | -7 | hSpCas9 | negative selection | 12327474 |