Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:114769
• Symbol:CARD16
• Description:caspase recruitment domain family member 16

DataSource: http://genomecrispr.dkfz.de/#!/results/CARD16

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
105044404	105044427	11	-	26472758	Jiyoye	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.3377105618427735	[233]	[222]	2	hSpCas9	negative selection	23466
105044483	105044506	11	+	26472758	Jiyoye	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	-0.7874720493476702	[102]	[44]	-5	hSpCas9	negative selection	23468
105044554	105044577	11	-	26472758	Jiyoye	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.21688693890422295	[560]	[363]	-1	hSpCas9	negative selection	23469
105041426	105041449	11	+	26472758	Jiyoye	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	-0.24749609102668724	[158]	[100]	-2	hSpCas9	negative selection	23470
105041628	105041651	11	-	26472758	Jiyoye	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.29261561724301777	[130]	[120]	2	hSpCas9	negative selection	23471
105041496	105041519	11	-	26472758	Jiyoye	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.3179080434087862	[99]	[93]	2	hSpCas9	negative selection	23472
105041664	105041687	11	+	26472758	Jiyoye	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	4.930737337562886	[0]	[22]	9	hSpCas9	negative selection	23473
105044391	105044414	11	-	26472758	Jiyoye	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-0.7303281422440615	[54]	[24]	-5	hSpCas9	negative selection	23474
105041535	105041558	11	-	26472758	Jiyoye	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	-0.40695807318279265	[159]	[90]	-3	hSpCas9	negative selection	23475
105041702	105041725	11	-	26472758	Jiyoye	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	-0.2831401193615113	[141]	[87]	-2	hSpCas9	negative selection	23476
105044644	105044667	11	-	26472758	Jiyoye	viability	CCAAACAGACAAGGTCCTGAAGG	CARD16	ENSG00000204397	-0.4783658939092118	[108]	[58]	-3	hSpCas9	negative selection	23487
105041695	105041718	11	+	26472758	Jiyoye	viability	GGGTTGTCCTGCACTGCCTGAAG	CARD16	ENSG00000204397	0.2885308850072544	[75]	[69]	2	hSpCas9	negative selection	23708
105044404	105044427	11	-	26472758	KBM7	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.6997776681045392	[1071,767]	[898,510]	7	hSpCas9	negative selection	214584
105044483	105044506	11	+	26472758	KBM7	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	0.6160781605245731	[246,160]	[133,153]	6	hSpCas9	negative selection	214586
105044554	105044577	11	-	26472758	KBM7	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.7632767024053937	[1492,1353]	[1420,880]	8	hSpCas9	negative selection	214587
105041426	105041449	11	+	26472758	KBM7	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.8757801204443192	[599,609]	[770,304]	8	hSpCas9	negative selection	214588
105041628	105041651	11	-	26472758	KBM7	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.29587510364738984	[550,342]	[278,229]	3	hSpCas9	negative selection	214589
105041496	105041519	11	-	26472758	KBM7	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.6908594845148475	[360,278]	[195,280]	7	hSpCas9	negative selection	214590
105041664	105041687	11	+	26472758	KBM7	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	0.7634390567819463	[222,320]	[256,190]	8	hSpCas9	negative selection	214591
105044391	105044414	11	-	26472758	KBM7	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-0.26375250425529395	[170,131]	[42,72]	-3	hSpCas9	negative selection	214592
105041535	105041558	11	-	26472758	KBM7	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	-0.12600969542013984	[338,367]	[168,139]	-1	hSpCas9	negative selection	214593
105041702	105041725	11	-	26472758	KBM7	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	1.3773114643028	[405,464]	[854,254]	9	hSpCas9	negative selection	214594
105044644	105044667	11	-	26472758	KBM7	viability	CCAAACAGACAAGGTCCTGAAGG	CARD16	ENSG00000204397	0.4364742476271595	[474,391]	[340,214]	5	hSpCas9	negative selection	214605
105041695	105041718	11	+	26472758	KBM7	viability	GGGTTGTCCTGCACTGCCTGAAG	CARD16	ENSG00000204397	0.8995327647990601	[385,384]	[325,351]	8	hSpCas9	negative selection	214826
105044404	105044427	11	-	26472758	Raji	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	-0.3323160181395135	[471]	[86]	-3	hSpCas9	negative selection	405702
105044483	105044506	11	+	26472758	Raji	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	-0.17272438381913569	[101]	[20]	-1	hSpCas9	negative selection	405704
105044554	105044577	11	-	26472758	Raji	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.967395818085391	[464]	[210]	8	hSpCas9	negative selection	405705
105041426	105041449	11	+	26472758	Raji	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.7669590968688476	[156]	[61]	7	hSpCas9	negative selection	405706
105041628	105041651	11	-	26472758	Raji	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.8498873130812356	[207]	[86]	7	hSpCas9	negative selection	405707
105041496	105041519	11	-	26472758	Raji	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.3819398111026128	[290]	[87]	3	hSpCas9	negative selection	405708
105041664	105041687	11	+	26472758	Raji	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	1.0004683314570875	[55]	[25]	8	hSpCas9	negative selection	405709
105044391	105044414	11	-	26472758	Raji	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-4.477578965347557	[95]	[0]	-9	hSpCas9	negative selection	405710
105041535	105041558	11	-	26472758	Raji	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.7485901467343749	[217]	[84]	7	hSpCas9	negative selection	405711
105041702	105041725	11	-	26472758	Raji	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.41706803450621477	[141]	[43]	4	hSpCas9	negative selection	405712
105044644	105044667	11	-	26472758	Raji	viability	CCAAACAGACAAGGTCCTGAAGG	CARD16	ENSG00000204397	0.4964258261194988	[167]	[54]	5	hSpCas9	negative selection	405723
105041695	105041718	11	+	26472758	Raji	viability	GGGTTGTCCTGCACTGCCTGAAG	CARD16	ENSG00000204397	-0.20797190559027667	[218]	[43]	-2	hSpCas9	negative selection	405944
105044404	105044427	11	-	26472758	K562	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.3810417539579315	[744]	[818]	3	hSpCas9	negative selection	596820
105044483	105044506	11	+	26472758	K562	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	0.14573445280704012	[241]	[225]	1	hSpCas9	negative selection	596822
105044554	105044577	11	-	26472758	K562	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.4003543338796265	[1208]	[1346]	3	hSpCas9	negative selection	596823
105041426	105041449	11	+	26472758	K562	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	1.0842615024729556	[413]	[740]	8	hSpCas9	negative selection	596824
105041628	105041651	11	-	26472758	K562	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.6554431644386672	[269]	[358]	5	hSpCas9	negative selection	596825
105041496	105041519	11	-	26472758	K562	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.993267313348575	[265]	[446]	8	hSpCas9	negative selection	596826
105041664	105041687	11	+	26472758	K562	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	2.0209126860192903	[161]	[554]	9	hSpCas9	negative selection	596827
105044391	105044414	11	-	26472758	K562	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	0.6994226342629355	[88]	[121]	6	hSpCas9	negative selection	596828
105041535	105041558	11	-	26472758	K562	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.9461634617634521	[339]	[552]	7	hSpCas9	negative selection	596829
105041702	105041725	11	-	26472758	K562	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.027320605999512193	[407]	[350]	0	hSpCas9	negative selection	596830
105044644	105044667	11	-	26472758	K562	viability	CCAAACAGACAAGGTCCTGAAGG	CARD16	ENSG00000204397	-0.11815135171826138	[350]	[272]	-1	hSpCas9	negative selection	596841
105041695	105041718	11	+	26472758	K562	viability	GGGTTGTCCTGCACTGCCTGAAG	CARD16	ENSG00000204397	0.829381228387603	[297]	[446]	7	hSpCas9	negative selection	597062
105071701	105071724	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCAACAGAGAGTGTATCTTTGG	CARD16	ENSG00000204397	-1.1004281373792884	[179,492]	[14,55]	-6	dCas9-VP64	positive selection	2388091
105045504	105045527	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGATCAGGGTAGGAGGGGAATGG	CARD16	ENSG00000204397	1.5803287739276748	[56,77]	[78,6]	6	dCas9-VP64	positive selection	2416606
105045427	105045450	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACAGTTCTGATTCTTTCTCTGGG	CARD16	ENSG00000204397	2.656346283063073	[579,238]	[491,644]	8	dCas9-VP64	positive selection	2461917
105045479	105045502	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATTCTTTTTTCTCCAGCCCTTGG	CARD16	ENSG00000204397	-0.3118529633484812	[133,141]	[40,5]	-1	dCas9-VP64	positive selection	2461918
105045454	105045477	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCATCAGAGAGTGTATCCAAGG	CARD16	ENSG00000204397	1.527291328271563	[172,111]	[22,162]	5	dCas9-VP64	positive selection	2461919
105071701	105071724	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCAACAGAGAGTGTATCTTTGG	CARD16	ENSG00000204397	-0.29177922422115493	[148,106]	[36,30]	-3	dCas9-VP64	positive selection	2483346
105045504	105045527	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGATCAGGGTAGGAGGGGAATGG	CARD16	ENSG00000204397	0.06651584267111366	[193,139]	[37,74]	0	dCas9-VP64	positive selection	2511861
105045427	105045450	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACAGTTCTGATTCTTTCTCTGGG	CARD16	ENSG00000204397	1.4678923219670366	[968,398]	[1077,197]	7	dCas9-VP64	positive selection	2557172
105045479	105045502	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATTCTTTTTTCTCCAGCCCTTGG	CARD16	ENSG00000204397	-0.05598546264399917	[140,219]	[47,63]	0	dCas9-VP64	positive selection	2557173
105045454	105045477	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCATCAGAGAGTGTATCCAAGG	CARD16	ENSG00000204397	0.07641777942124084	[62,95]	[14,37]	0	dCas9-VP64	positive selection	2557174
105044385	105044408	11	-	27013184	SW480	treatment with recombinant TRAIL	CTGGGACTCTCAGCAGGTAAGGG	CARD16	ENSG00000204397	-2.19142203134687	[681,1199]	[75,101]	-7	hSpCas9	positive selection	2960411
105044464	105044487	11	-	27013184	SW480	treatment with recombinant TRAIL	CGTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	-0.5957109725751712	[73,82]	[18,26]	-3	hSpCas9	positive selection	2960421
105044470	105044493	11	-	27013184	SW480	treatment with recombinant TRAIL	TGACTCCGTTATTCCGAAAGGGG	CARD16	ENSG00000204397	-1.2982032496272673	[516,725]	[47,191]	-5	hSpCas9	positive selection	2960422
105044471	105044494	11	-	27013184	SW480	treatment with recombinant TRAIL	TTGACTCCGTTATTCCGAAAGGG	CARD16	ENSG00000204397	-1.2860118484593257	[563,540]	[66,141]	-5	hSpCas9	positive selection	2960425
105044472	105044495	11	-	27013184	SW480	treatment with recombinant TRAIL	ATTGACTCCGTTATTCCGAAAGG	CARD16	ENSG00000204397	0.016512409543518736	[232,377]	[125,136]	0	hSpCas9	positive selection	2960426
105044512	105044535	11	-	27013184	SW480	treatment with recombinant TRAIL	ACGTGAAAATGCTACAGTTATGG	CARD16	ENSG00000204397	1.1426643749971248	[318,316]	[300,305]	5	hSpCas9	positive selection	2960429
105044587	105044610	11	-	27013184	SW480	treatment with recombinant TRAIL	AGGTACAATAAATGGCTTACTGG	CARD16	ENSG00000204397	1.226634024632515	[69,179]	[169,51]	6	hSpCas9	positive selection	2960431
105044465	105044488	11	+	27013184	SW480	treatment with recombinant TRAIL	CTGTGCCCCTTTCGGAATAACGG	CARD16	ENSG00000204397	-1.1433371193023492	[253,373]	[56,64]	-5	hSpCas9	positive selection	2960447
105044482	105044505	11	+	27013184	SW480	treatment with recombinant TRAIL	TAACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	0.24183774056347218	[44,43]	[11,37]	1	hSpCas9	positive selection	2960450
105044483	105044506	11	+	27013184	SW480	treatment with recombinant TRAIL	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	1.1526905166958028	[113,140]	[121,119]	5	hSpCas9	positive selection	2960452
105044597	105044620	11	+	27013184	SW480	treatment with recombinant TRAIL	ATTTATTGTACCTTCACCCATGG	CARD16	ENSG00000204397	-0.04477191799304717	[184,213]	[39,143]	0	hSpCas9	positive selection	2960454
105044602	105044625	11	+	27013184	SW480	treatment with recombinant TRAIL	TTGTACCTTCACCCATGGAATGG	CARD16	ENSG00000204397	1.5412782341574744	[9,83]	[44,68]	7	hSpCas9	positive selection	2960456
105045277	105045300	11	+	27013184	SW480	treatment with recombinant TRAIL	AGTAAAAGACTCACCGGCCATGG	CARD16	ENSG00000204397	-0.7683775065986378	[30,75]	[17,5]	-3	hSpCas9	positive selection	2960457
105045277	105045300	11	+	27013184	SW480	treatment with recombinant TRAIL	AGTAAAAGACTCACCGGCCATGG	CARD16	ENSG00000204397	-0.7766506409059908	[40,72]	[13,13]	-4	hSpCas9	positive selection	2960460
105044613	105044636	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGCTGTTTATCCATTCCATGGG	CARD16	ENSG00000204397	0.14084134544239219	[4,4]	[4,3]	3	hSpCas9	positive selection	2976304
105044566	105044589	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATGAATTATTACAGACAAGGG	CARD16	ENSG00000204397	-0.5985430467723809	[3,3]	[2,0]	-7	hSpCas9	positive selection	2976305
105044545	105044568	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTGCTGAACCAGGAAGAGATGG	CARD16	ENSG00000204397	0.3760100086326169	[3,3]	[4,3]	7	hSpCas9	positive selection	2976306
105045290	105045313	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TAGGAGAGAAAAGCCATGGCCGG	CARD16	ENSG00000204397	-0.2884392982075632	[4,3]	[3,1]	-4	hSpCas9	positive selection	2976307
105044613	105044636	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGCTGTTTATCCATTCCATGGG	CARD16	ENSG00000204397	0.09069035537578415	[4,4]	[3,2]	1	hSpCas9	positive selection	3044162
105044566	105044589	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATGAATTATTACAGACAAGGG	CARD16	ENSG00000204397	-0.06649402879462493	[3,3]	[2,2]	-1	hSpCas9	positive selection	3044163
105044545	105044568	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTGCTGAACCAGGAAGAGATGG	CARD16	ENSG00000204397	-0.14696341701792612	[3,3]	[4,0]	-2	hSpCas9	positive selection	3044164
105045290	105045313	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TAGGAGAGAAAAGCCATGGCCGG	CARD16	ENSG00000204397	-0.3288142644768788	[4,4]	[4,0]	-5	hSpCas9	positive selection	3044165
105044554	105044577		-	24336571	A375	resistance to PLX after 7 days	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.4884518096600474	[38,32]	[50,49]	9	hSpCas9	positive selection	3160612
105041499	105041522		+	24336571	A375	resistance to PLX after 7 days	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.09514424077296502	[4,5]	[5,4]	3	hSpCas9	positive selection	3160613
105044391	105044414		-	24336571	A375	resistance to PLX after 7 days	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-0.002001701156370439	[5,4]	[5,4]	0	hSpCas9	positive selection	3160614
105041628	105041651		-	24336571	A375	resistance to PLX after 7 days	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	-0.04195393087684085	[1,1]	[1,1]	-1	hSpCas9	positive selection	3160615
105043515	105043538		+	24336571	A375	resistance to PLX after 7 days	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	-0.024937609084346918	[15,12]	[14,13]	0	hSpCas9	positive selection	3160616
105044554	105044577		-	24336571	A375	resistance to PLX after 14 days	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	4.877669612227855	[40,23]	[480,426]	9	hSpCas9	positive selection	3218405
105041499	105041522		+	24336571	A375	resistance to PLX after 14 days	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.4652072552243578	[4,1]	[1,1]	4	hSpCas9	positive selection	3218406
105044391	105044414		-	24336571	A375	resistance to PLX after 14 days	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-0.31602793587795475	[5,6]	[1,1]	-4	hSpCas9	positive selection	3218407
105041628	105041651		-	24336571	A375	resistance to PLX after 14 days	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.5269151496158733	[2,1]	[1,1]	5	hSpCas9	positive selection	3218408
105043515	105043538		+	24336571	A375	resistance to PLX after 14 days	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.3269325509229385	[9,13]	[8,3]	3	hSpCas9	positive selection	3218409
105044554	105044577		-	24336571	A375	viability after 7 days	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.21564592726923304	[32]	[38,32]	3	hSpCas9	negative selection	3276198
105041499	105041522		+	24336571	A375	viability after 7 days	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.8199888167261912	[9]	[4,5]	-8	hSpCas9	negative selection	3276199
105044391	105044414		-	24336571	A375	viability after 7 days	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-0.9730699382212492	[11]	[5,4]	-8	hSpCas9	negative selection	3276200
105041628	105041651		-	24336571	A375	viability after 7 days	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	-0.14012635781728733	[2]	[1,1]	-2	hSpCas9	negative selection	3276201
105043515	105043538		+	24336571	A375	viability after 7 days	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.26740812704382333	[12]	[15,12]	4	hSpCas9	negative selection	3276202
105044554	105044577		-	24336571	A375	viability after 14 days	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.0828307537484867	[32]	[40,23]	1	hSpCas9	negative selection	3333991
105041499	105041522		+	24336571	A375	viability after 14 days	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-1.2817526015640128	[9]	[4,1]	-9	hSpCas9	negative selection	3333992
105044391	105044414		-	24336571	A375	viability after 14 days	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-0.7530953194710307	[11]	[5,6]	-7	hSpCas9	negative selection	3333993
105041628	105041651		-	24336571	A375	viability after 14 days	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.12156270652177859	[2]	[2,1]	1	hSpCas9	negative selection	3333994
105043515	105043538		+	24336571	A375	viability after 14 days	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.006317829720381439	[12]	[9,13]	0	hSpCas9	negative selection	3333995
105041628	105041651	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.3442412582014466	[122,117]	[0,0]	1	hSpCas9	positive selection	3341044
105041425	105041448	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	-1.3720065968732476	[394,396]	[0,0]	-8	hSpCas9	positive selection	3341045
105043515	105043538	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	-1.3310944914626894	[372,396]	[0,0]	-8	hSpCas9	positive selection	3341046
105044614	105044637	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.24609895602258094	[128,128]	[0,0]	1	hSpCas9	positive selection	3360290
105044554	105044577	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.4637729772613501	[210,210]	[0,0]	-3	hSpCas9	positive selection	3360291
105041499	105041522	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	1.8310614567437373	[42,42]	[0,0]	7	hSpCas9	positive selection	3360292
105044613	105044636	11	-	26780180	HT29	viability (Avana library 4 designs)	AAGCTGTTTATCCATTCCATGGG	CARD16	ENSG00000204397	-0.266871793929313	[]	[]	-4	hSpCas9	negative selection	3412583
105044566	105044589	11	-	26780180	HT29	viability (Avana library 4 designs)	GGATGAATTATTACAGACAAGGG	CARD16	ENSG00000204397	0.0942204325215149	[]	[]	0	hSpCas9	negative selection	3412584
105044545	105044568	11	-	26780180	HT29	viability (Avana library 4 designs)	GGTGCTGAACCAGGAAGAGATGG	CARD16	ENSG00000204397	0.244683124306613	[]	[]	0	hSpCas9	negative selection	3412585
105045290	105045313	11	-	26780180	HT29	viability (Avana library 4 designs)	TAGGAGAGAAAAGCCATGGCCGG	CARD16	ENSG00000204397	1.18779397520295	[]	[]	4	hSpCas9	negative selection	3412586
105044566	105044589	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGAATTATTACAGACAAGGG	CARD16	ENSG00000204397	-9.46356644653704	[]	[]	-7	hSpCas9	negative selection	3488118
105044613	105044636	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAGCTGTTTATCCATTCCATGGG	CARD16	ENSG00000204397	-3.9780107740465	[]	[]	-4	hSpCas9	negative selection	3488119
105044545	105044568	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGCTGAACCAGGAAGAGATGG	CARD16	ENSG00000204397	0.188007297560902	[]	[]	0	hSpCas9	negative selection	3488120
105045290	105045313	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	TAGGAGAGAAAAGCCATGGCCGG	CARD16	ENSG00000204397	-2.49568010657145	[]	[]	-3	hSpCas9	negative selection	3488121
105044644	105044667	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAACAGACAAGGTCCTGAAGG	CARD16	ENSG00000204397	-2.52825661441143	[]	[]	-3	hSpCas9	negative selection	3488122
105045277	105045300	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTAAAAGACTCACCGGCCATGG	CARD16	ENSG00000204397	2.82054991811211	[]	[]	4	hSpCas9	negative selection	3488123
105044566	105044589	11	-	26780180	A375	viability (Avana lentiGuide)	GGATGAATTATTACAGACAAGGG	CARD16	ENSG00000204397	-1.07278252738587	[]	[]	-2	hSpCas9	negative selection	3596777
105044613	105044636	11	-	26780180	A375	viability (Avana lentiGuide)	AAGCTGTTTATCCATTCCATGGG	CARD16	ENSG00000204397	-2.37339601176951	[]	[]	-4	hSpCas9	negative selection	3596778
105044545	105044568	11	-	26780180	A375	viability (Avana lentiGuide)	GGTGCTGAACCAGGAAGAGATGG	CARD16	ENSG00000204397	-6.53723647036284	[]	[]	-9	hSpCas9	negative selection	3596779
105045290	105045313	11	-	26780180	A375	viability (Avana lentiGuide)	TAGGAGAGAAAAGCCATGGCCGG	CARD16	ENSG00000204397	10.2180404256499	[]	[]	7	hSpCas9	negative selection	3596780
105044644	105044667	11	-	26780180	A375	viability (Avana lentiGuide)	CCAAACAGACAAGGTCCTGAAGG	CARD16	ENSG00000204397	0.408943861367879	[]	[]	0	hSpCas9	negative selection	3596781
105045277	105045300	11	+	26780180	A375	viability (Avana lentiGuide)	AGTAAAAGACTCACCGGCCATGG	CARD16	ENSG00000204397	5.31611943996548	[]	[]	5	hSpCas9	negative selection	3596782
105044566	105044589	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGAATTATTACAGACAAGGG	CARD16	ENSG00000204397	-0.8423223776117936	[7]	[5,2]	-8	hSpCas9	positive selection	3705436
105044613	105044636	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGCTGTTTATCCATTCCATGGG	CARD16	ENSG00000204397	-0.22132295663568724	[6]	[5,5]	-3	hSpCas9	positive selection	3705437
105044545	105044568	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGCTGAACCAGGAAGAGATGG	CARD16	ENSG00000204397	-0.2150021737311599	[4]	[3,3]	-3	hSpCas9	positive selection	3705438
105045290	105045313	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TAGGAGAGAAAAGCCATGGCCGG	CARD16	ENSG00000204397	-0.0574535459549137	[6]	[5,5]	-1	hSpCas9	positive selection	3705439
105044644	105044667	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAACAGACAAGGTCCTGAAGG	CARD16	ENSG00000204397	-0.16988763767005635	[5]	[5,4]	-3	hSpCas9	positive selection	3705440
105045277	105045300	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTAAAAGACTCACCGGCCATGG	CARD16	ENSG00000204397	0.1639377839188048	[6]	[7,7]	4	hSpCas9	positive selection	3705441
105044566	105044589	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGAATTATTACAGACAAGGG	CARD16	ENSG00000204397	0.08415468265689516	[5]	[4,4]	1	hSpCas9	positive selection	3814043
105044613	105044636	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGCTGTTTATCCATTCCATGGG	CARD16	ENSG00000204397	0.05915050765683977	[5]	[6,3]	1	hSpCas9	positive selection	3814044
105044545	105044568	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGCTGAACCAGGAAGAGATGG	CARD16	ENSG00000204397	0.3042842074970236	[5]	[6,4]	8	hSpCas9	positive selection	3814045
105045290	105045313	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TAGGAGAGAAAAGCCATGGCCGG	CARD16	ENSG00000204397	0.16333348011314613	[5]	[4,6]	4	hSpCas9	positive selection	3814046
105044644	105044667	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAACAGACAAGGTCCTGAAGG	CARD16	ENSG00000204397	0.18596169989822198	[6]	[6,6]	4	hSpCas9	positive selection	3814047
105045277	105045300	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTAAAAGACTCACCGGCCATGG	CARD16	ENSG00000204397	0.11067004826807869	[7]	[6,6]	2	hSpCas9	positive selection	3814048
105044614	105044637	11	-	26780180	A375	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.251694850001342	[]	[]	0	hSpCas9	negative selection	3922346
105044554	105044577	11	-	26780180	A375	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	1.29786662207926	[]	[]	7	hSpCas9	negative selection	3922347
105041499	105041522	11	+	26780180	A375	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.640056623966232	[]	[]	2	hSpCas9	negative selection	3922348
105041628	105041651	11	-	26780180	A375	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	1.24097676355581	[]	[]	6	hSpCas9	negative selection	3922349
105041425	105041448	11	+	26780180	A375	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.533754145979421	[]	[]	1	hSpCas9	negative selection	3922350
105043515	105043538	11	+	26780180	A375	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	1.42040174661905	[]	[]	7	hSpCas9	negative selection	3922351
105044614	105044637	11	-	26780180	HT29	viability (GeCKOv2 library)	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	1.20887059543569	[]	[]	6	hSpCas9	negative selection	4030312
105044554	105044577	11	-	26780180	HT29	viability (GeCKOv2 library)	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	1.32060983236488	[]	[]	6	hSpCas9	negative selection	4030313
105041499	105041522	11	+	26780180	HT29	viability (GeCKOv2 library)	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	1.32295407468116	[]	[]	6	hSpCas9	negative selection	4030314
105041628	105041651	11	-	26780180	HT29	viability (GeCKOv2 library)	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	1.12116117153353	[]	[]	5	hSpCas9	negative selection	4030315
105041425	105041448	11	+	26780180	HT29	viability (GeCKOv2 library)	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.768480160018378	[]	[]	3	hSpCas9	negative selection	4030316
105043515	105043538	11	+	26780180	HT29	viability (GeCKOv2 library)	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	1.12648869287149	[]	[]	5	hSpCas9	negative selection	4030317
105044554	105044577	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.6869683121019953	[5]	[3,8]	9	hSpCas9	positive selection	4188701
105041499	105041522	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.004724581720157772	[2]	[1,0]	0	hSpCas9	positive selection	4188702
105044391	105044414	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-0.21207793012788578	[3]	[2,0]	-5	hSpCas9	positive selection	4188703
105041628	105041651	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	-0.019780696034371714	[1]	[1,0]	0	hSpCas9	positive selection	4188704
105043515	105043538	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.15482602838263573	[3]	[2,2]	4	hSpCas9	positive selection	4188705
105044554	105044577	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.501572079821166	[4]	[4,3,5,0]	3	hSpCas9	positive selection	4252723
105041499	105041522	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	1.0996768965553123	[2]	[0,0,1,3]	8	hSpCas9	positive selection	4252724
105044391	105044414	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-0.12654635133958764	[3]	[0,3,1,0]	-2	hSpCas9	positive selection	4252725
105041628	105041651	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.07049390690048035	[2]	[1,2,0,0]	0	hSpCas9	positive selection	4252726
105043515	105043538	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	-0.15066142304284474	[3]	[2,1,1,0]	-2	hSpCas9	positive selection	4252727
105041628	105041651	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.27365890536190807	[2]	[2,1]	5	hSpCas9	positive selection	4260926
105041425	105041448	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.24152874364256133	[3]	[4,2]	5	hSpCas9	positive selection	4260927
105043515	105043538	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.2909961881026224	[4]	[4,4]	6	hSpCas9	positive selection	4260928
105044614	105044637	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.26688306006421014	[2]	[2,2]	5	hSpCas9	positive selection	4325204
105044554	105044577	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.1545513290855662	[2]	[2,2]	3	hSpCas9	positive selection	4325205
105041499	105041522	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.4578341560100674	[1]	[0,0]	-7	hSpCas9	positive selection	4325206
105041580	105041602	11	+	27760321	OCIAML3	viability	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-0.7079741423649697	[0,2]	[0,0]	-6	hSpCas9	negative selection	4385651
105041665	105041687	11	-	27760321	OCIAML3	viability	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.5245735359672177	[633,448]	[583,626]	6	hSpCas9	negative selection	4385652
105044464	105044486	11	-	27760321	OCIAML3	viability	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	0.07414694891246909	[232,197]	[122,246]	0	hSpCas9	negative selection	4385653
105044483	105044505	11	+	27760321	OCIAML3	viability	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	-0.21362863450717196	[253,223]	[146,178]	-2	hSpCas9	negative selection	4385654
105044537	105044559	11	+	27760321	OCIAML3	viability	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	0.8154480120047223	[416,361]	[453,639]	8	hSpCas9	negative selection	4385655
105044554	105044576	11	-	27760321	OCIAML3	viability	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.4891294032132215	[507,455]	[488,579]	6	hSpCas9	negative selection	4385656
105044567	105044589	11	-	27760321	OCIAML3	viability	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	1.3129538012937756	[15,24]	[31,51]	9	hSpCas9	negative selection	4385657
105041580	105041602	11	+	27760321	OCIAML2	viability	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-0.7567195076300184	[0,2]	[0,0]	-7	hSpCas9	negative selection	4469114
105041665	105041687	11	-	27760321	OCIAML2	viability	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.01733936713202011	[633,448]	[435,441]	0	hSpCas9	negative selection	4469115
105044464	105044486	11	-	27760321	OCIAML2	viability	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	0.22367848138858715	[232,197]	[157,261]	3	hSpCas9	negative selection	4469116
105044483	105044505	11	+	27760321	OCIAML2	viability	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	-0.18197348296224825	[253,223]	[132,218]	-2	hSpCas9	negative selection	4469117
105044537	105044559	11	+	27760321	OCIAML2	viability	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	0.5685360860449862	[416,361]	[428,514]	7	hSpCas9	negative selection	4469118
105044554	105044576	11	-	27760321	OCIAML2	viability	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.9790411248534505	[507,455]	[746,794]	9	hSpCas9	negative selection	4469119
105044567	105044589	11	-	27760321	OCIAML2	viability	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	-0.5499829266069796	[15,24]	[11,10]	-6	hSpCas9	negative selection	4469120
105041580	105041602	11	+	27760321	MV411	viability	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-0.46289557345028776	[0,2]	[0,0]	-3	hSpCas9	negative selection	4552577
105041665	105041687	11	-	27760321	MV411	viability	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.09120018179019534	[633,448]	[336,435]	0	hSpCas9	negative selection	4552578
105044464	105044486	11	-	27760321	MV411	viability	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	0.6342402656068188	[232,197]	[193,258]	5	hSpCas9	negative selection	4552579
105044483	105044505	11	+	27760321	MV411	viability	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	1.2362813424848038	[253,223]	[455,242]	8	hSpCas9	negative selection	4552580
105044537	105044559	11	+	27760321	MV411	viability	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	-0.8523247189261958	[416,361]	[153,123]	-5	hSpCas9	negative selection	4552581
105044554	105044576	11	-	27760321	MV411	viability	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.06074653573913798	[507,455]	[314,288]	0	hSpCas9	negative selection	4552582
105044567	105044589	11	-	27760321	MV411	viability	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	-3.78828450206571	[15,24]	[0,0]	-9	hSpCas9	negative selection	4552583
105041580	105041602	11	+	27760321	HL60	viability	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-0.7707657352444244	[0,2]	[0,0]	-7	hSpCas9	negative selection	4636040
105041665	105041687	11	-	27760321	HL60	viability	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.145878779024607	[633,448]	[571,390]	1	hSpCas9	negative selection	4636041
105044464	105044486	11	-	27760321	HL60	viability	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	-0.3677405097501072	[232,197]	[167,101]	-4	hSpCas9	negative selection	4636042
105044483	105044505	11	+	27760321	HL60	viability	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	-0.32704678037919	[253,223]	[116,195]	-4	hSpCas9	negative selection	4636043
105044537	105044559	11	+	27760321	HL60	viability	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	0.33755081050343916	[416,361]	[335,469]	4	hSpCas9	negative selection	4636044
105044554	105044576	11	-	27760321	HL60	viability	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.22588977470248864	[507,455]	[424,496]	2	hSpCas9	negative selection	4636045
105044567	105044589	11	-	27760321	HL60	viability	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	1.3791039174355788	[15,24]	[43,44]	9	hSpCas9	negative selection	4636046
105041580	105041602	11	+	27760321	HT1080	viability	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-0.2793348068021002	[2,2]	[0,0]	-1	hSpCas9	negative selection	4719503
105041665	105041687	11	-	27760321	HT1080	viability	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	1.0864782522761973	[448,350]	[420,247]	6	hSpCas9	negative selection	4719504
105044464	105044486	11	-	27760321	HT1080	viability	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	-2.5594174350202197	[197,154]	[20,1]	-7	hSpCas9	negative selection	4719505
105044483	105044505	11	+	27760321	HT1080	viability	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	1.4202080305463398	[223,174]	[195,230]	7	hSpCas9	negative selection	4719506
105044537	105044559	11	+	27760321	HT1080	viability	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	0.5333470414619024	[361,282]	[163,209]	3	hSpCas9	negative selection	4719507
105044554	105044576	11	-	27760321	HT1080	viability	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.825695924766615	[455,355]	[226,351]	4	hSpCas9	negative selection	4719508
105044567	105044589	11	-	27760321	HT1080	viability	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	-3.166245333808321	[24,19]	[0,0]	-7	hSpCas9	negative selection	4719509
105041580	105041602	11	+	27760321	HT29	viability after 7 days	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-1.9689950603513644	[2,2]	[0,0,0]	-9	hSpCas9	negative selection	4802966
105041665	105041687	11	-	27760321	HT29	viability after 7 days	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.6743576035672436	[448,350]	[811,762,882]	8	hSpCas9	negative selection	4802967
105044464	105044486	11	-	27760321	HT29	viability after 7 days	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	0.3555935290733029	[197,154]	[293,212,361]	5	hSpCas9	negative selection	4802968
105044483	105044505	11	+	27760321	HT29	viability after 7 days	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	0.4409415070647936	[223,174]	[398,418,236]	6	hSpCas9	negative selection	4802969
105044537	105044559	11	+	27760321	HT29	viability after 7 days	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	-0.21674882485202568	[361,282]	[291,546,225]	-3	hSpCas9	negative selection	4802970
105044554	105044576	11	-	27760321	HT29	viability after 7 days	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.10219664090545846	[455,355]	[464,749,454]	1	hSpCas9	negative selection	4802971
105044567	105044589	11	-	27760321	HT29	viability after 7 days	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	-0.36691778656501617	[24,19]	[14,50,0]	-5	hSpCas9	negative selection	4802972
105041580	105041602	11	+	27760321	HT29	viability after 25 days	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-1.799017071648624	[2,2]	[0,0,0]	-8	hSpCas9	negative selection	4886429
105041665	105041687	11	-	27760321	HT29	viability after 25 days	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.838941800478783	[448,350]	[668,762,1053]	8	hSpCas9	negative selection	4886430
105044464	105044486	11	-	27760321	HT29	viability after 25 days	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	-0.7346976318001832	[197,154]	[134,137,85]	-6	hSpCas9	negative selection	4886431
105044483	105044505	11	+	27760321	HT29	viability after 25 days	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	0.0559668520411577	[223,174]	[167,189,370]	0	hSpCas9	negative selection	4886432
105044537	105044559	11	+	27760321	HT29	viability after 25 days	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	-0.30308620248042195	[361,282]	[329,280,280]	-3	hSpCas9	negative selection	4886433
105044554	105044576	11	-	27760321	HT29	viability after 25 days	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.4771004910265453	[455,355]	[644,590,706]	5	hSpCas9	negative selection	4886434
105044567	105044589	11	-	27760321	HT29	viability after 25 days	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	0.5309286706335947	[24,19]	[33,29,48]	6	hSpCas9	negative selection	4886435
105041580	105041602	11	+	27760321	HT29	viability after 22 days	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-1.8163357035078835	[2,2]	[0,0,0]	-8	hSpCas9	negative selection	4969892
105041665	105041687	11	-	27760321	HT29	viability after 22 days	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.7573551803673971	[448,350]	[707,878,759]	8	hSpCas9	negative selection	4969893
105044464	105044486	11	-	27760321	HT29	viability after 22 days	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	-0.5002373928625126	[197,154]	[82,154,196]	-4	hSpCas9	negative selection	4969894
105044483	105044505	11	+	27760321	HT29	viability after 22 days	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	0.194218543816562	[223,174]	[295,206,287]	2	hSpCas9	negative selection	4969895
105044537	105044559	11	+	27760321	HT29	viability after 22 days	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	-0.07150071093691387	[361,282]	[279,380,405]	0	hSpCas9	negative selection	4969896
105044554	105044576	11	-	27760321	HT29	viability after 22 days	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.614025756554526	[455,355]	[696,705,752]	7	hSpCas9	negative selection	4969897
105044567	105044589	11	-	27760321	HT29	viability after 22 days	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	1.026483716868754	[24,19]	[34,38,85]	9	hSpCas9	negative selection	4969898
105041580	105041602	11	+	27760321	HT29	viability after 19 days	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-1.8004956510846704	[2,2]	[0,0,0]	-8	hSpCas9	negative selection	5053355
105041665	105041687	11	-	27760321	HT29	viability after 19 days	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	1.1412075347866315	[448,350]	[1351,551,1152]	9	hSpCas9	negative selection	5053356
105044464	105044486	11	-	27760321	HT29	viability after 19 days	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	-0.5134559628489919	[197,154]	[130,200,92]	-4	hSpCas9	negative selection	5053357
105044483	105044505	11	+	27760321	HT29	viability after 19 days	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	0.6299127294406044	[223,174]	[290,205,547]	6	hSpCas9	negative selection	5053358
105044537	105044559	11	+	27760321	HT29	viability after 19 days	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	0.5153888536449179	[361,282]	[746,559,305]	5	hSpCas9	negative selection	5053359
105044554	105044576	11	-	27760321	HT29	viability after 19 days	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.6163864578876938	[455,355]	[569,912,639]	6	hSpCas9	negative selection	5053360
105044567	105044589	11	-	27760321	HT29	viability after 19 days	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	1.3056971421313386	[24,19]	[70,87,33]	9	hSpCas9	negative selection	5053361
105041580	105041602	11	+	27760321	HT29	viability after 16 days	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-1.7690311986637486	[2,2]	[0,0,0]	-8	hSpCas9	negative selection	5136818
105041665	105041687	11	-	27760321	HT29	viability after 16 days	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.8574878185291476	[448,350]	[878,776,783]	8	hSpCas9	negative selection	5136819
105044464	105044486	11	-	27760321	HT29	viability after 16 days	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	-0.8261559604455719	[197,154]	[129,108,96]	-6	hSpCas9	negative selection	5136820
105044483	105044505	11	+	27760321	HT29	viability after 16 days	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	0.6950093337386768	[223,174]	[587,224,295]	7	hSpCas9	negative selection	5136821
105044537	105044559	11	+	27760321	HT29	viability after 16 days	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	0.08200190063854637	[361,282]	[377,321,446]	0	hSpCas9	negative selection	5136822
105044554	105044576	11	-	27760321	HT29	viability after 16 days	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.26579581276818287	[455,355]	[350,694,569]	3	hSpCas9	negative selection	5136823
105044567	105044589	11	-	27760321	HT29	viability after 16 days	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	1.0082700055368519	[24,19]	[45,76,27]	9	hSpCas9	negative selection	5136824
105041580	105041602	11	+	27760321	HT29	viability after 13 days	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-1.8213185981078865	[2,2]	[0,0,0]	-8	hSpCas9	negative selection	5220281
105041665	105041687	11	-	27760321	HT29	viability after 13 days	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.6242125194918569	[448,350]	[850,586,707]	7	hSpCas9	negative selection	5220282
105044464	105044486	11	-	27760321	HT29	viability after 13 days	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	-0.45395476186086436	[197,154]	[111,159,174]	-5	hSpCas9	negative selection	5220283
105044483	105044505	11	+	27760321	HT29	viability after 13 days	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	-0.48028633194610804	[223,174]	[50,144,293]	-5	hSpCas9	negative selection	5220284
105044537	105044559	11	+	27760321	HT29	viability after 13 days	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	-0.15815152948695355	[361,282]	[461,231,312]	-2	hSpCas9	negative selection	5220285
105044554	105044576	11	-	27760321	HT29	viability after 13 days	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.22960197014751713	[455,355]	[539,500,611]	3	hSpCas9	negative selection	5220286
105044567	105044589	11	-	27760321	HT29	viability after 13 days	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	0.8056173308357963	[24,19]	[17,36,79]	9	hSpCas9	negative selection	5220287
105041580	105041602	11	+	27760321	HT29	viability after 10 days	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-1.9273299052682304	[2,2]	[0,0,0]	-9	hSpCas9	negative selection	5303744
105041665	105041687	11	-	27760321	HT29	viability after 10 days	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	0.6050069209633717	[448,350]	[795,964,528]	8	hSpCas9	negative selection	5303745
105044464	105044486	11	-	27760321	HT29	viability after 10 days	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	-0.3699260202332926	[197,154]	[153,184,172]	-5	hSpCas9	negative selection	5303746
105044483	105044505	11	+	27760321	HT29	viability after 10 days	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	0.25618201876982405	[223,174]	[335,330,227]	3	hSpCas9	negative selection	5303747
105044537	105044559	11	+	27760321	HT29	viability after 10 days	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	-0.22998204762971736	[361,282]	[356,456,221]	-3	hSpCas9	negative selection	5303748
105044554	105044576	11	-	27760321	HT29	viability after 10 days	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.0229852611750391	[455,355]	[641,395,503]	0	hSpCas9	negative selection	5303749
105044567	105044589	11	-	27760321	HT29	viability after 10 days	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	0.3760210435620639	[24,19]	[53,17,36]	5	hSpCas9	negative selection	5303750
105041580	105041602	11	+	27760321	MOLM13	viability	TATTATTGTATTCTGAACATGG	CARD16	ENSG00000204397	-0.2368387606226925	[0,2]	[0,0]	-1	hSpCas9	negative selection	5387207
105041665	105041687	11	-	27760321	MOLM13	viability	CCACATGCTCAAGCCCAGAAGG	CARD16	ENSG00000204397	1.3234639162576192	[633,448]	[683,817]	8	hSpCas9	negative selection	5387208
105044464	105044486	11	-	27760321	MOLM13	viability	GTTATTCCGAAAGGGGCACAGG	CARD16	ENSG00000204397	1.535049598155815	[232,197]	[227,455]	9	hSpCas9	negative selection	5387209
105044483	105044505	11	+	27760321	MOLM13	viability	AACGGAGTCAATCAAAGCTCGG	CARD16	ENSG00000204397	2.506741693408918	[253,223]	[1350,265]	9	hSpCas9	negative selection	5387210
105044537	105044559	11	+	27760321	MOLM13	viability	TACTTTCTCCATCTCTTCCTGG	CARD16	ENSG00000204397	1.354526805993711	[416,361]	[196,869]	8	hSpCas9	negative selection	5387211
105044554	105044576	11	-	27760321	MOLM13	viability	CAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.842730331888386	[507,455]	[225,87]	-5	hSpCas9	negative selection	5387212
105044567	105044589	11	-	27760321	MOLM13	viability	GGATGAATTATTACAGACAAGG	CARD16	ENSG00000204397	-0.45445916385837215	[15,24]	[6,9]	-3	hSpCas9	negative selection	5387213
105045230	105045253	11	-	27661255	K562	viability	GAAAGAGTTGTGGAAAGGGCTGG	CARD16	ENSG00000204397	0.019542220833773716	[605,632]	[565,445]	0	dCas9-KRAB	negative selection	5468107
105041628	105041651	11	-	27260156	BXPC3	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.23285044338177685	[311]	[425,300,417,386]	5	hSpCas9	negative selection	5533386
105041425	105041448	11	+	27260156	BXPC3	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.42508244766453784	[940]	[1435,1178,1166,1508]	8	hSpCas9	negative selection	5533387
105043515	105043538	11	+	27260156	BXPC3	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	-0.01886325638637354	[1253]	[1011,1377,1282,1551]	0	hSpCas9	negative selection	5533388
105044614	105044637	11	-	27260156	BXPC3	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.268385300734073	[376]	[376,456,491,596]	6	hSpCas9	negative selection	5597664
105044554	105044577	11	-	27260156	BXPC3	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.2182165212904191	[451]	[402,588,603,622]	5	hSpCas9	negative selection	5597665
105041499	105041522	11	+	27260156	BXPC3	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.342402810479129	[112]	[84,78,110,99]	-6	hSpCas9	negative selection	5597666
105041628	105041651	11	-	27260156	A673	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.20984247629617075	[311]	[512,287,532,408]	5	hSpCas9	negative selection	5654637
105041425	105041448	11	+	27260156	A673	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.34948648692584405	[940]	[1620,1315,1417,1423]	7	hSpCas9	negative selection	5654638
105043515	105043538	11	+	27260156	A673	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.0085582407649063	[1253]	[1600,1329,1542,1600]	0	hSpCas9	negative selection	5654639
105044614	105044637	11	-	27260156	A673	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	-0.03485580456552395	[376]	[476,399,359,540]	-1	hSpCas9	negative selection	5718915
105044554	105044577	11	-	27260156	A673	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.013716286229491871	[451]	[592,422,488,660]	0	hSpCas9	negative selection	5718916
105041499	105041522	11	+	27260156	A673	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.3966852844413209	[112]	[112,82,108,108]	-7	hSpCas9	negative selection	5718917
105041628	105041651	11	-	27260156	A375	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.5091514705599581	[311]	[450,795,551,333]	7	hSpCas9	negative selection	5775888
105041425	105041448	11	+	27260156	A375	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.5906247861767389	[940]	[1499,1924,1945,1319]	8	hSpCas9	negative selection	5775889
105043515	105043538	11	+	27260156	A375	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.2769109470480473	[1253]	[1915,2030,1793,1428]	4	hSpCas9	negative selection	5775890
105044614	105044637	11	-	27260156	A375	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.47830165770667554	[376]	[591,832,593,478]	7	hSpCas9	negative selection	5840166
105044554	105044577	11	-	27260156	A375	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.11548251138012586	[451]	[465,498,497,485]	-2	hSpCas9	negative selection	5840167
105041499	105041522	11	+	27260156	A375	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.19942458522873352	[112]	[190,272,73,91]	3	hSpCas9	negative selection	5840168
105041628	105041651	11	-	27260156	COLO741	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.20710550116850263	[311]	[462,473,443]	4	hSpCas9	negative selection	5897139
105041425	105041448	11	+	27260156	COLO741	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.012067251225355013	[940]	[1352,1370,942]	0	hSpCas9	negative selection	5897140
105043515	105043538	11	+	27260156	COLO741	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.14081465952437777	[1253]	[2513,1335,1525]	3	hSpCas9	negative selection	5897141
105044614	105044637	11	-	27260156	COLO741	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.3229783467953055	[376]	[550,591,654]	6	hSpCas9	negative selection	5961417
105044554	105044577	11	-	27260156	COLO741	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.016772486834012938	[451]	[708,488,527]	0	hSpCas9	negative selection	5961418
105041499	105041522	11	+	27260156	COLO741	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.2829649595928543	[112]	[151,80,124]	-6	hSpCas9	negative selection	5961419
105041628	105041651	11	-	27260156	CAL120	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.08180911283997538	[311]	[363,423,436]	1	hSpCas9	negative selection	6018390
105041425	105041448	11	+	27260156	CAL120	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.6651285861631617	[940]	[1836,1330,2388]	8	hSpCas9	negative selection	6018391
105043515	105043538	11	+	27260156	CAL120	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.09635947699606962	[1253]	[1459,1580,1926]	1	hSpCas9	negative selection	6018392
105044614	105044637	11	-	27260156	CAL120	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.08952595971672678	[376]	[490,557,447]	1	hSpCas9	negative selection	6082668
105044554	105044577	11	-	27260156	CAL120	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.5799894413929119	[451]	[386,351,390]	-7	hSpCas9	negative selection	6082669
105041499	105041522	11	+	27260156	CAL120	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.3315627264197598	[112]	[64,86,174]	-5	hSpCas9	negative selection	6082670
105041628	105041651	11	-	27260156	CADOES1	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.43821759376950803	[311]	[436,264,407,464]	7	hSpCas9	negative selection	6139641
105041425	105041448	11	+	27260156	CADOES1	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.6881238948257775	[940]	[1504,1455,1274,1403]	9	hSpCas9	negative selection	6139642
105043515	105043538	11	+	27260156	CADOES1	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.18395652550293407	[1253]	[1195,1352,1348,1404]	3	hSpCas9	negative selection	6139643
105044614	105044637	11	-	27260156	CADOES1	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.1994821424040153	[376]	[251,296,648,412]	3	hSpCas9	negative selection	6203919
105044554	105044577	11	-	27260156	CADOES1	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.17754058192883743	[451]	[373,382,379,348]	-3	hSpCas9	negative selection	6203920
105041499	105041522	11	+	27260156	CADOES1	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.532253650364882	[112]	[161,114,174,155]	8	hSpCas9	negative selection	6203921
105041628	105041651	11	-	27260156	EWS502	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.4858719744801452	[311]	[447,518,534,338]	8	hSpCas9	negative selection	6260892
105041425	105041448	11	+	27260156	EWS502	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.4406944837491389	[940]	[1335,1250,1403,1426]	7	hSpCas9	negative selection	6260893
105043515	105043538	11	+	27260156	EWS502	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.06835047835214891	[1253]	[1257,1117,1810,1412]	1	hSpCas9	negative selection	6260894
105044614	105044637	11	-	27260156	EWS502	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.29348629840764406	[376]	[444,565,480,463]	5	hSpCas9	negative selection	6325170
105044554	105044577	11	-	27260156	EWS502	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.3362548950288564	[451]	[550,726,577,556]	6	hSpCas9	negative selection	6325171
105041499	105041522	11	+	27260156	EWS502	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.2139187514940697	[112]	[99,142,73,92]	-4	hSpCas9	negative selection	6325172
105041628	105041651	11	-	27260156	EW8	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.23930103212457127	[311]	[335,321,294,244]	4	hSpCas9	negative selection	6382143
105041425	105041448	11	+	27260156	EW8	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.384559907757541	[940]	[1017,1137,946,887]	7	hSpCas9	negative selection	6382144
105043515	105043538	11	+	27260156	EW8	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.026398260417957342	[1253]	[1357,1092,884,862]	0	hSpCas9	negative selection	6382145
105044614	105044637	11	-	27260156	EW8	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.044838960130887784	[376]	[339,388,243,301]	0	hSpCas9	negative selection	6446421
105044554	105044577	11	-	27260156	EW8	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.08942738239415779	[451]	[470,428,194,320]	-2	hSpCas9	negative selection	6446422
105041499	105041522	11	+	27260156	EW8	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.0030182338859132685	[112]	[83,148,39,101]	0	hSpCas9	negative selection	6446423
105041628	105041651	11	-	27260156	CORL105	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.4931476804444029	[311]	[482,567,462,531]	8	hSpCas9	negative selection	6503394
105041425	105041448	11	+	27260156	CORL105	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.4645709733393819	[940]	[1622,1387,1407,1648]	8	hSpCas9	negative selection	6503395
105043515	105043538	11	+	27260156	CORL105	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.27515853580378447	[1253]	[1528,1421,2392,1855]	5	hSpCas9	negative selection	6503396
105044614	105044637	11	-	27260156	CORL105	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.31270487181773965	[376]	[592,473,670,476]	6	hSpCas9	negative selection	6567672
105044554	105044577	11	-	27260156	CORL105	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.33242243466477567	[451]	[711,480,725,759]	6	hSpCas9	negative selection	6567673
105041499	105041522	11	+	27260156	CORL105	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.07015763163814936	[112]	[171,112,187,91]	1	hSpCas9	negative selection	6567674
105041628	105041651	11	-	27260156	HS294T	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.39292276594117204	[311]	[149,128,136,230]	5	hSpCas9	negative selection	6624645
105041425	105041448	11	+	27260156	HS294T	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.5016720173791347	[940]	[505,433,394,769]	6	hSpCas9	negative selection	6624646
105043515	105043538	11	+	27260156	HS294T	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.20812976200963185	[1253]	[571,439,471,796]	3	hSpCas9	negative selection	6624647
105044614	105044637	11	-	27260156	HS294T	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	-0.2942685048705653	[376]	[97,151,121,100]	-4	hSpCas9	negative selection	6688923
105044554	105044577	11	-	27260156	HS294T	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.15395518570084338	[451]	[114,217,141,331]	2	hSpCas9	negative selection	6688924
105041499	105041522	11	+	27260156	HS294T	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.23682893974845642	[112]	[40,47,50,69]	3	hSpCas9	negative selection	6688925
105041628	105041651	11	-	27260156	HCC44	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.6319679400411227	[311]	[635,468,536,557]	9	hSpCas9	negative selection	6745896
105041425	105041448	11	+	27260156	HCC44	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.54080449837948	[940]	[2145,1346,1466,1297]	8	hSpCas9	negative selection	6745897
105043515	105043538	11	+	27260156	HCC44	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.34596202719965596	[1253]	[2121,1631,1989,1545]	5	hSpCas9	negative selection	6745898
105044614	105044637	11	-	27260156	HCC44	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	-0.08971135705773259	[376]	[395,366,653,235]	-1	hSpCas9	negative selection	6810174
105044554	105044577	11	-	27260156	HCC44	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.20860621381859912	[451]	[690,504,673,525]	3	hSpCas9	negative selection	6810175
105041499	105041522	11	+	27260156	HCC44	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.24515435141281916	[112]	[140,104,103,83]	-4	hSpCas9	negative selection	6810176
105041628	105041651	11	-	27260156	G402	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.915116402420832	[311]	[1070,314,847,664]	9	hSpCas9	negative selection	6867147
105041425	105041448	11	+	27260156	G402	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.5465548268734919	[940]	[1816,1220,1652,1988]	6	hSpCas9	negative selection	6867148
105043515	105043538	11	+	27260156	G402	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.3670394578463434	[1253]	[2692,2079,1522,1712]	4	hSpCas9	negative selection	6867149
105044614	105044637	11	-	27260156	G402	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.20144293062002952	[376]	[518,580,754,272]	2	hSpCas9	negative selection	6931425
105044554	105044577	11	-	27260156	G402	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.2571894824723613	[451]	[589,540,461,1006]	3	hSpCas9	negative selection	6931426
105041499	105041522	11	+	27260156	G402	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.12675865049389534	[112]	[185,112,118,95]	-1	hSpCas9	negative selection	6931427
105041628	105041651	11	-	27260156	L33	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.34387506017658676	[311]	[376,153,262,412]	7	hSpCas9	negative selection	6988398
105041425	105041448	11	+	27260156	L33	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.2958289076090861	[940]	[1142,522,650,1164]	6	hSpCas9	negative selection	6988399
105043515	105043538	11	+	27260156	L33	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	-0.01096183867669076	[1253]	[1143,537,779,1281]	0	hSpCas9	negative selection	6988400
105044614	105044637	11	-	27260156	L33	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	-0.04809330194160982	[376]	[328,158,219,391]	-1	hSpCas9	negative selection	7052676
105044554	105044577	11	-	27260156	L33	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.10366497010768205	[451]	[429,118,296,488]	-2	hSpCas9	negative selection	7052677
105041499	105041522	11	+	27260156	L33	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.15970384473144805	[112]	[169,38,57,145]	3	hSpCas9	negative selection	7052678
105041628	105041651	11	-	27260156	K562	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.7591907771356418	[311]	[327,673,374,491]	8	hSpCas9	negative selection	7109649
105041425	105041448	11	+	27260156	K562	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.538104743060025	[940]	[994,887,1617,1298]	7	hSpCas9	negative selection	7109650
105043515	105043538	11	+	27260156	K562	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.39836487157651734	[1253]	[1492,949,1881,1505]	5	hSpCas9	negative selection	7109651
105044614	105044637	11	-	27260156	K562	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	1.2002941793307609	[376]	[595,317,1322,793]	9	hSpCas9	negative selection	7173927
105044554	105044577	11	-	27260156	K562	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.28345478117967005	[451]	[289,339,565,704]	3	hSpCas9	negative selection	7173928
105041499	105041522	11	+	27260156	K562	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.44691680971838954	[112]	[162,76,175,129]	5	hSpCas9	negative selection	7173929
105041628	105041651	11	-	27260156	HT29	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.5048256634553514	[311]	[533,587,584,455]	8	hSpCas9	negative selection	7230900
105041425	105041448	11	+	27260156	HT29	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.334722533348659	[940]	[1446,1645,1325,1367]	6	hSpCas9	negative selection	7230901
105043515	105043538	11	+	27260156	HT29	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.26711275737654105	[1253]	[1727,2000,2094,1542]	5	hSpCas9	negative selection	7230902
105044614	105044637	11	-	27260156	HT29	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.4026410792968427	[376]	[607,585,515,695]	7	hSpCas9	negative selection	7295178
105044554	105044577	11	-	27260156	HT29	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.11566621759892906	[451]	[649,720,524,506]	2	hSpCas9	negative selection	7295179
105041499	105041522	11	+	27260156	HT29	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.22508372289629341	[112]	[169,97,239,131]	4	hSpCas9	negative selection	7295180
105041628	105041651	11	-	27260156	MHHES1	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.2987453360872535	[311]	[393,575,380,387]	5	hSpCas9	negative selection	7352151
105041425	105041448	11	+	27260156	MHHES1	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.37842602999611663	[940]	[1890,1472,1171,1082]	6	hSpCas9	negative selection	7352152
105043515	105043538	11	+	27260156	MHHES1	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.22686430459629303	[1253]	[2095,1805,1593,1242]	4	hSpCas9	negative selection	7352153
105044614	105044637	11	-	27260156	MHHES1	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.4524398326164337	[376]	[584,800,461,502]	7	hSpCas9	negative selection	7416429
105044554	105044577	11	-	27260156	MHHES1	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.2942710060626495	[451]	[518,551,548,799]	5	hSpCas9	negative selection	7416430
105041499	105041522	11	+	27260156	MHHES1	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.32436064707742096	[112]	[164,167,54,43]	-6	hSpCas9	negative selection	7416431
105041628	105041651	11	-	27260156	MEWO	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.48463458689498984	[311]	[529,356,361]	8	hSpCas9	negative selection	7473402
105041425	105041448	11	+	27260156	MEWO	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.1652260822226308	[940]	[1108,975,899]	3	hSpCas9	negative selection	7473403
105043515	105043538	11	+	27260156	MEWO	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	-0.09932142131096144	[1253]	[1112,1022,1152]	-2	hSpCas9	negative selection	7473404
105044614	105044637	11	-	27260156	MEWO	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.23651591715494125	[376]	[396,401,443]	5	hSpCas9	negative selection	7537680
105044554	105044577	11	-	27260156	MEWO	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.20187063272676006	[451]	[413,339,357]	-4	hSpCas9	negative selection	7537681
105041499	105041522	11	+	27260156	MEWO	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.07341996523350613	[112]	[117,110,105]	1	hSpCas9	negative selection	7537682
105041628	105041651	11	-	27260156	LNCAPCLONEFGC	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.2909377571055901	[311]	[292,346,373,373]	4	hSpCas9	negative selection	7594653
105041425	105041448	11	+	27260156	LNCAPCLONEFGC	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.6913369180214597	[940]	[1222,1296,1651,1381]	9	hSpCas9	negative selection	7594654
105043515	105043538	11	+	27260156	LNCAPCLONEFGC	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.2534658080376402	[1253]	[1246,1128,1700,1406]	4	hSpCas9	negative selection	7594655
105044614	105044637	11	-	27260156	LNCAPCLONEFGC	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.13843138602828328	[376]	[290,294,413,515]	2	hSpCas9	negative selection	7658931
105044554	105044577	11	-	27260156	LNCAPCLONEFGC	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.09319375694987173	[451]	[450,306,570,445]	1	hSpCas9	negative selection	7658932
105041499	105041522	11	+	27260156	LNCAPCLONEFGC	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.06854998559724024	[112]	[88,108,98,92]	-1	hSpCas9	negative selection	7658933
105041628	105041651	11	-	27260156	PANC0327	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.1711807542154063	[311]	[436,182,285,368]	2	hSpCas9	negative selection	7715904
105041425	105041448	11	+	27260156	PANC0327	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.7356857695456374	[940]	[1044,1153,2166,1204]	9	hSpCas9	negative selection	7715905
105043515	105043538	11	+	27260156	PANC0327	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.39406841475275334	[1253]	[1198,1298,1415,1939]	6	hSpCas9	negative selection	7715906
105044614	105044637	11	-	27260156	PANC0327	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.5369642806822459	[376]	[461,537,572,361]	7	hSpCas9	negative selection	7780182
105044554	105044577	11	-	27260156	PANC0327	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.7546944978958317	[451]	[785,492,972,490]	9	hSpCas9	negative selection	7780183
105041499	105041522	11	+	27260156	PANC0327	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.5249834525866746	[112]	[111,80,41,45]	-6	hSpCas9	negative selection	7780184
105041628	105041651	11	-	27260156	NCIH2009	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.864645069704705	[311]	[1348,388,758]	9	hSpCas9	negative selection	7837155
105041425	105041448	11	+	27260156	NCIH2009	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.4893090891913112	[940]	[1927,1838,1782]	6	hSpCas9	negative selection	7837156
105043515	105043538	11	+	27260156	NCIH2009	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.11978780789330967	[1253]	[2244,1648,1885]	1	hSpCas9	negative selection	7837157
105044614	105044637	11	-	27260156	NCIH2009	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.35670233395830764	[376]	[657,399,965]	5	hSpCas9	negative selection	7901433
105044554	105044577	11	-	27260156	NCIH2009	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.03942379369778294	[451]	[740,599,623]	0	hSpCas9	negative selection	7901434
105041499	105041522	11	+	27260156	NCIH2009	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.7475001499384017	[112]	[315,308,178]	8	hSpCas9	negative selection	7901435
105041628	105041651	11	-	27260156	NCIH1373	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.6661266421897786	[311]	[286,567,880,110]	6	hSpCas9	negative selection	7958406
105041425	105041448	11	+	27260156	NCIH1373	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.9524870315614715	[940]	[2122,2162,1904,514]	8	hSpCas9	negative selection	7958407
105043515	105043538	11	+	27260156	NCIH1373	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.9299275981930903	[1253]	[3437,2999,1897,642]	8	hSpCas9	negative selection	7958408
105044614	105044637	11	-	27260156	NCIH1373	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.16996836580559443	[376]	[466,352,573,135]	1	hSpCas9	negative selection	8022684
105044554	105044577	11	-	27260156	NCIH1373	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.4250185029874122	[451]	[1256,323,361,242]	4	hSpCas9	negative selection	8022685
105041499	105041522	11	+	27260156	NCIH1373	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	1.2201576793056397	[112]	[555,142,216,84]	9	hSpCas9	negative selection	8022686
105041628	105041651	11	-	27260156	PATU8902	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.4574559784977108	[311]	[760,715,307,679]	5	hSpCas9	negative selection	8079657
105041425	105041448	11	+	27260156	PATU8902	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.7274499321620216	[940]	[2491,2158,1525,2712]	7	hSpCas9	negative selection	8079658
105043515	105043538	11	+	27260156	PATU8902	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.18449177011036144	[1253]	[1727,2415,1539,2409]	1	hSpCas9	negative selection	8079659
105044614	105044637	11	-	27260156	PATU8902	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.7544472138644343	[376]	[1238,835,623,901]	7	hSpCas9	negative selection	8143935
105044554	105044577	11	-	27260156	PATU8902	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.304027649092942	[451]	[1082,613,855,489]	3	hSpCas9	negative selection	8143936
105041499	105041522	11	+	27260156	PATU8902	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.29673033894805223	[112]	[221,211,282,8]	3	hSpCas9	negative selection	8143937
105041628	105041651	11	-	27260156	PANC1	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.6921055274142633	[311]	[737,472,309,236]	9	hSpCas9	negative selection	8200908
105041425	105041448	11	+	27260156	PANC1	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.5728547312110157	[940]	[1329,1327,1302,901]	8	hSpCas9	negative selection	8200909
105043515	105043538	11	+	27260156	PANC1	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.2736329531114532	[1253]	[1405,1566,1327,989]	4	hSpCas9	negative selection	8200910
105044614	105044637	11	-	27260156	PANC1	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.4894891783762493	[376]	[354,534,367,553]	7	hSpCas9	negative selection	8265186
105044554	105044577	11	-	27260156	PANC1	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.09651337197241461	[451]	[485,507,302,378]	1	hSpCas9	negative selection	8265187
105041499	105041522	11	+	27260156	PANC1	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.28194294106806184	[112]	[127,118,131,94]	4	hSpCas9	negative selection	8265188
105041628	105041651	11	-	27260156	PANC0813	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.32724034382102307	[311]	[554,526,399,369]	5	hSpCas9	negative selection	8322159
105041425	105041448	11	+	27260156	PANC0813	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.3272970288653534	[940]	[1488,1101,1499,1459]	5	hSpCas9	negative selection	8322160
105043515	105043538	11	+	27260156	PANC0813	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.2247686768608026	[1253]	[2235,1470,1772,1464]	3	hSpCas9	negative selection	8322161
105044614	105044637	11	-	27260156	PANC0813	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	-0.03208074950085882	[376]	[555,304,376,500]	0	hSpCas9	negative selection	8386437
105044554	105044577	11	-	27260156	PANC0813	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.17522307455367367	[451]	[855,382,465,708]	3	hSpCas9	negative selection	8386438
105041499	105041522	11	+	27260156	PANC0813	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.24543089253037031	[112]	[186,178,148,118]	4	hSpCas9	negative selection	8386439
105041628	105041651	11	-	27260156	RDES	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.19591204504779047	[311]	[345,415,392,502]	3	hSpCas9	negative selection	8443410
105041425	105041448	11	+	27260156	RDES	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.5216874998190313	[940]	[1250,1417,1870,1747]	8	hSpCas9	negative selection	8443411
105043515	105043538	11	+	27260156	RDES	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.010515635546944013	[1253]	[1171,1437,1620,1630]	0	hSpCas9	negative selection	8443412
105044614	105044637	11	-	27260156	RDES	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.2434604042211931	[376]	[411,569,479,603]	4	hSpCas9	negative selection	8507688
105044554	105044577	11	-	27260156	RDES	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.3049046366890675	[451]	[554,635,584,815]	5	hSpCas9	negative selection	8507689
105041499	105041522	11	+	27260156	RDES	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.32576319675586585	[112]	[80,201,175,209]	5	hSpCas9	negative selection	8507690
105041628	105041651	11	-	27260156	PC3	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.39888505115184825	[311]	[253,370,807,392]	8	hSpCas9	negative selection	8564661
105041425	105041448	11	+	27260156	PC3	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.13087646359267668	[940]	[708,909,1821,1013]	3	hSpCas9	negative selection	8564662
105043515	105043538	11	+	27260156	PC3	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	-0.021374583436938988	[1253]	[1059,740,2083,1323]	0	hSpCas9	negative selection	8564663
105044614	105044637	11	-	27260156	PC3	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.28076991949483987	[376]	[236,495,719,534]	6	hSpCas9	negative selection	8628939
105044554	105044577	11	-	27260156	PC3	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.17099425793659437	[451]	[240,502,602,355]	-4	hSpCas9	negative selection	8628940
105041499	105041522	11	+	27260156	PC3	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.2913859890313495	[112]	[85,109,218,180]	6	hSpCas9	negative selection	8628941
105041628	105041651	11	-	27260156	PATU8988T	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.4521182624735759	[311]	[187,529,421,529]	7	hSpCas9	negative selection	8685912
105041425	105041448	11	+	27260156	PATU8988T	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.5169004506590713	[940]	[1187,1297,1465,1244]	8	hSpCas9	negative selection	8685913
105043515	105043538	11	+	27260156	PATU8988T	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.2625203557217253	[1253]	[1486,1390,1249,1702]	4	hSpCas9	negative selection	8685914
105044614	105044637	11	-	27260156	PATU8988T	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.3866047369564324	[376]	[501,483,385,539]	6	hSpCas9	negative selection	8750190
105044554	105044577	11	-	27260156	PATU8988T	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.04684454103475089	[451]	[273,728,383,443]	0	hSpCas9	negative selection	8750191
105041499	105041522	11	+	27260156	PATU8988T	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.370297064645174	[112]	[34,79,114,108]	-6	hSpCas9	negative selection	8750192
105041628	105041651	11	-	27260156	T47D	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.3988789920475925	[311]	[558,348,509,510]	8	hSpCas9	negative selection	8807163
105041425	105041448	11	+	27260156	T47D	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.34192578675360297	[940]	[1576,1213,1378,1403]	7	hSpCas9	negative selection	8807164
105043515	105043538	11	+	27260156	T47D	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.15426253039013216	[1253]	[1547,1446,1821,1699]	3	hSpCas9	negative selection	8807165
105044614	105044637	11	-	27260156	T47D	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.27046508877535436	[376]	[478,573,526,534]	6	hSpCas9	negative selection	8871441
105044554	105044577	11	-	27260156	T47D	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.14558780990631	[451]	[464,452,416,574]	-3	hSpCas9	negative selection	8871442
105041499	105041522	11	+	27260156	T47D	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.008918121225350184	[112]	[167,73,195,87]	0	hSpCas9	negative selection	8871443
105041628	105041651	11	-	27260156	SU8686	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.5467560559632512	[311]	[516,460,405,401]	8	hSpCas9	negative selection	8928414
105041425	105041448	11	+	27260156	SU8686	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.42844474944632194	[940]	[1125,1136,1324,1495]	7	hSpCas9	negative selection	8928415
105043515	105043538	11	+	27260156	SU8686	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.28592544213469595	[1253]	[1546,1355,1378,1834]	5	hSpCas9	negative selection	8928416
105044614	105044637	11	-	27260156	SU8686	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.29908504659495205	[376]	[411,263,445,799]	5	hSpCas9	negative selection	8992692
105044554	105044577	11	-	27260156	SU8686	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	-0.00033422628023224016	[451]	[377,341,586,518]	0	hSpCas9	negative selection	8992693
105041499	105041522	11	+	27260156	SU8686	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.17913078204016197	[112]	[182,97,118,98]	3	hSpCas9	negative selection	8992694
105041628	105041651	11	-	27260156	SKES1	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.4205269315142209	[311]	[414,486,342,424]	8	hSpCas9	negative selection	9049665
105041425	105041448	11	+	27260156	SKES1	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.4014489623105384	[940]	[1348,1326,1097,1203]	8	hSpCas9	negative selection	9049666
105043515	105043538	11	+	27260156	SKES1	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	-0.033174721676399566	[1253]	[1439,1181,1357,952]	0	hSpCas9	negative selection	9049667
105044614	105044637	11	-	27260156	SKES1	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.3917304202399227	[376]	[458,569,613,345]	7	hSpCas9	negative selection	9113943
105044554	105044577	11	-	27260156	SKES1	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.22878259909927778	[451]	[533,587,490,505]	5	hSpCas9	negative selection	9113944
105041499	105041522	11	+	27260156	SKES1	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.04007588684127361	[112]	[192,76,142,39]	-1	hSpCas9	negative selection	9113945
105041628	105041651	11	-	27260156	TOV112D	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	-0.10875685038493743	[311]	[291,316,245,309]	-2	hSpCas9	negative selection	9170916
105041425	105041448	11	+	27260156	TOV112D	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.41304554956109407	[940]	[977,1686,1453,988]	7	hSpCas9	negative selection	9170917
105043515	105043538	11	+	27260156	TOV112D	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.17079727311529314	[1253]	[1158,1855,1376,1349]	3	hSpCas9	negative selection	9170918
105044614	105044637	11	-	27260156	TOV112D	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.19934481321137393	[376]	[393,361,577,379]	4	hSpCas9	negative selection	9235194
105044554	105044577	11	-	27260156	TOV112D	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.1560497958242859	[451]	[572,566,429,468]	3	hSpCas9	negative selection	9235195
105041499	105041522	11	+	27260156	TOV112D	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	-0.0216286023165293	[112]	[113,62,70,183]	0	hSpCas9	negative selection	9235196
105041628	105041651	11	-	27260156	TC71	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.537656708681878	[311]	[364,626,538,406]	9	hSpCas9	negative selection	9292167
105041425	105041448	11	+	27260156	TC71	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.17014415192302468	[940]	[1005,1179,1107,1256]	4	hSpCas9	negative selection	9292168
105043515	105043538	11	+	27260156	TC71	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.03302680361577148	[1253]	[1372,1324,1332,1477]	0	hSpCas9	negative selection	9292169
105044614	105044637	11	-	27260156	TC71	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.2871147535393096	[376]	[472,619,441,435]	7	hSpCas9	negative selection	9356445
105044554	105044577	11	-	27260156	TC71	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.1284751429552897	[451]	[534,489,545,547]	3	hSpCas9	negative selection	9356446
105041499	105041522	11	+	27260156	TC71	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.05297246849497217	[112]	[119,111,115,156]	1	hSpCas9	negative selection	9356447
105041628	105041651	11	-	27260156	TC32	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.628212864004174	[311]	[362,504,516,396]	9	hSpCas9	negative selection	9413418
105041425	105041448	11	+	27260156	TC32	viability	TGCAACTCTTTACCTAAACCTGG	CARD16	ENSG00000204397	0.5200632221238268	[940]	[1422,743,1520,1548]	8	hSpCas9	negative selection	9413419
105043515	105043538	11	+	27260156	TC32	viability	TGTGTACTAAGCTAATTTCCAGG	CARD16	ENSG00000204397	0.10537460878922911	[1253]	[1336,871,1569,1417]	2	hSpCas9	negative selection	9413420
105044614	105044637	11	-	27260156	TC32	viability	AAAGCTGTTTATCCATTCCATGG	CARD16	ENSG00000204397	0.12231106252108598	[376]	[396,185,504,536]	2	hSpCas9	negative selection	9477696
105044554	105044577	11	-	27260156	TC32	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.34151596991022076	[451]	[466,654,526,421]	6	hSpCas9	negative selection	9477697
105041499	105041522	11	+	27260156	TC32	viability	CCAGAACCGCTCAATAAAATTGG	CARD16	ENSG00000204397	0.14200274884257302	[112]	[138,108,126,85]	2	hSpCas9	negative selection	9477698
105044404	105044427	11	-	28162770	P31FUJ	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.44585509126863154	[307]	[492]	5	hSpCas9	negative selection	10125921
105044483	105044506	11	+	28162770	P31FUJ	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	0.41196969154208113	[125]	[196]	4	hSpCas9	negative selection	10125922
105044554	105044577	11	-	28162770	P31FUJ	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.5192702821420359	[398]	[671]	6	hSpCas9	negative selection	10125923
105041426	105041449	11	+	28162770	P31FUJ	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.1765216436700716	[252]	[335]	1	hSpCas9	negative selection	10125924
105041628	105041651	11	-	28162770	P31FUJ	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.8559020208571015	[204]	[435]	8	hSpCas9	negative selection	10125925
105041496	105041519	11	-	28162770	P31FUJ	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	1.039110352765868	[134]	[325]	9	hSpCas9	negative selection	10125926
105041664	105041687	11	+	28162770	P31FUJ	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	0.6135746064724094	[98]	[177]	7	hSpCas9	negative selection	10125927
105044391	105044414	11	-	28162770	P31FUJ	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-1.9571677618009513	[75]	[22]	-8	hSpCas9	negative selection	10125928
105041535	105041558	11	-	28162770	P31FUJ	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.8986817207238589	[261]	[573]	8	hSpCas9	negative selection	10125929
105041702	105041725	11	-	28162770	P31FUJ	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	1.078512216448132	[190]	[473]	9	hSpCas9	negative selection	10125930
105044404	105044427	11	-	28162770	TF1	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	NaN	[NaN]	[232]	1	hSpCas9	negative selection	10295287
105044483	105044506	11	+	28162770	TF1	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10295288
105044554	105044577	11	-	28162770	TF1	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	NaN	[NaN]	[311]	1	hSpCas9	negative selection	10295289
105041426	105041449	11	+	28162770	TF1	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10295290
105041628	105041651	11	-	28162770	TF1	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10295291
105041496	105041519	11	-	28162770	TF1	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	NaN	[NaN]	[44]	1	hSpCas9	negative selection	10295292
105041664	105041687	11	+	28162770	TF1	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	NaN	[NaN]	[198]	1	hSpCas9	negative selection	10295293
105044391	105044414	11	-	28162770	TF1	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10295294
105041535	105041558	11	-	28162770	TF1	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	NaN	[NaN]	[329]	1	hSpCas9	negative selection	10295295
105041702	105041725	11	-	28162770	TF1	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	NaN	[NaN]	[248]	1	hSpCas9	negative selection	10295296
105044404	105044427	11	-	28162770	SKM1	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	-0.2564045221677804	[99]	[147]	-2	hSpCas9	negative selection	10464653
105044483	105044506	11	+	28162770	SKM1	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	0.3355395789644745	[25]	[57]	3	hSpCas9	negative selection	10464654
105044554	105044577	11	-	28162770	SKM1	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.7941554243027449	[121]	[373]	7	hSpCas9	negative selection	10464655
105041426	105041449	11	+	28162770	SKM1	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.46340052084024286	[63]	[155]	4	hSpCas9	negative selection	10464656
105041628	105041651	11	-	28162770	SKM1	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.6692463678769568	[52]	[148]	6	hSpCas9	negative selection	10464657
105041496	105041519	11	-	28162770	SKM1	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.04741419216785006	[51]	[94]	0	hSpCas9	negative selection	10464658
105041664	105041687	11	+	28162770	SKM1	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	1.1779983019779945	[22]	[91]	9	hSpCas9	negative selection	10464659
105044391	105044414	11	-	28162770	SKM1	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	0.6634251291482358	[4]	[13]	6	hSpCas9	negative selection	10464660
105041535	105041558	11	-	28162770	SKM1	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.6118948285081544	[56]	[153]	6	hSpCas9	negative selection	10464661
105041702	105041725	11	-	28162770	SKM1	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.15985095526773507	[39]	[78]	1	hSpCas9	negative selection	10464662
105044404	105044427	11	-	28162770	SKM1	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	-0.2564045221677804	[99]	[147]	-2	hSpCas9	negative selection	10634019
105044483	105044506	11	+	28162770	SKM1	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	0.3355395789644745	[25]	[57]	3	hSpCas9	negative selection	10634020
105044554	105044577	11	-	28162770	SKM1	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.7941554243027449	[121]	[373]	7	hSpCas9	negative selection	10634021
105041426	105041449	11	+	28162770	SKM1	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.46340052084024286	[63]	[155]	4	hSpCas9	negative selection	10634022
105041628	105041651	11	-	28162770	SKM1	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.6692463678769568	[52]	[148]	6	hSpCas9	negative selection	10634023
105041496	105041519	11	-	28162770	SKM1	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.04741419216785006	[51]	[94]	0	hSpCas9	negative selection	10634024
105041664	105041687	11	+	28162770	SKM1	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	1.1779983019779945	[22]	[91]	9	hSpCas9	negative selection	10634025
105044391	105044414	11	-	28162770	SKM1	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	0.6634251291482358	[4]	[13]	6	hSpCas9	negative selection	10634026
105041535	105041558	11	-	28162770	SKM1	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.6118948285081544	[56]	[153]	6	hSpCas9	negative selection	10634027
105041702	105041725	11	-	28162770	SKM1	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.15985095526773507	[39]	[78]	1	hSpCas9	negative selection	10634028
105044404	105044427	11	-	28162770	PL21	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.2519785460089382	[327]	[169]	2	hSpCas9	negative selection	10803385
105044483	105044506	11	+	28162770	PL21	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	-0.48791637919593933	[86]	[26]	-3	hSpCas9	negative selection	10803386
105044554	105044577	11	-	28162770	PL21	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.21875529265666716	[384]	[194]	2	hSpCas9	negative selection	10803387
105041426	105041449	11	+	28162770	PL21	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.3140958037864058	[291]	[157]	2	hSpCas9	negative selection	10803388
105041628	105041651	11	-	28162770	PL21	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	-0.4309930676647621	[253]	[81]	-3	hSpCas9	negative selection	10803389
105041496	105041519	11	-	28162770	PL21	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	1.3678670602273866	[145]	[163]	9	hSpCas9	negative selection	10803390
105041664	105041687	11	+	28162770	PL21	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	-1.0585946539108482	[66]	[13]	-6	hSpCas9	negative selection	10803391
105044391	105044414	11	-	28162770	PL21	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	0.30705481840583193	[51]	[27]	2	hSpCas9	negative selection	10803392
105041535	105041558	11	-	28162770	PL21	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.6635401353295629	[131]	[90]	6	hSpCas9	negative selection	10803393
105041702	105041725	11	-	28162770	PL21	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.2438609919186383	[129]	[66]	2	hSpCas9	negative selection	10803394
105044404	105044427	11	-	28162770	P31FUJ	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.44585509126863154	[307]	[492]	5	hSpCas9	negative selection	10972751
105044483	105044506	11	+	28162770	P31FUJ	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	0.41196969154208113	[125]	[196]	4	hSpCas9	negative selection	10972752
105044554	105044577	11	-	28162770	P31FUJ	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.5192702821420359	[398]	[671]	6	hSpCas9	negative selection	10972753
105041426	105041449	11	+	28162770	P31FUJ	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.1765216436700716	[252]	[335]	1	hSpCas9	negative selection	10972754
105041628	105041651	11	-	28162770	P31FUJ	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.8559020208571015	[204]	[435]	8	hSpCas9	negative selection	10972755
105041496	105041519	11	-	28162770	P31FUJ	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	1.039110352765868	[134]	[325]	9	hSpCas9	negative selection	10972756
105041664	105041687	11	+	28162770	P31FUJ	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	0.6135746064724094	[98]	[177]	7	hSpCas9	negative selection	10972757
105044391	105044414	11	-	28162770	P31FUJ	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-1.9571677618009513	[75]	[22]	-8	hSpCas9	negative selection	10972758
105041535	105041558	11	-	28162770	P31FUJ	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.8986817207238589	[261]	[573]	8	hSpCas9	negative selection	10972759
105041702	105041725	11	-	28162770	P31FUJ	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	1.078512216448132	[190]	[473]	9	hSpCas9	negative selection	10972760
105044404	105044427	11	-	28162770	OCIAML5	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	1.2894361100992315	[130]	[577]	9	hSpCas9	negative selection	11142117
105044483	105044506	11	+	28162770	OCIAML5	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	1.9073936610892956	[34]	[236]	9	hSpCas9	negative selection	11142118
105044554	105044577	11	-	28162770	OCIAML5	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.14793342913600305	[251]	[503]	1	hSpCas9	negative selection	11142119
105041426	105041449	11	+	28162770	OCIAML5	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	-0.5620089912636566	[237]	[290]	-4	hSpCas9	negative selection	11142120
105041628	105041651	11	-	28162770	OCIAML5	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	-0.22797773885301964	[193]	[298]	-2	hSpCas9	negative selection	11142121
105041496	105041519	11	-	28162770	OCIAML5	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.609837533452821	[105]	[291]	5	hSpCas9	negative selection	11142122
105041664	105041687	11	+	28162770	OCIAML5	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	1.3682633840155585	[49]	[232]	9	hSpCas9	negative selection	11142123
105044391	105044414	11	-	28162770	OCIAML5	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	0.6885018104987055	[21]	[63]	6	hSpCas9	negative selection	11142124
105041535	105041558	11	-	28162770	OCIAML5	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.6032347986285739	[158]	[435]	5	hSpCas9	negative selection	11142125
105041702	105041725	11	-	28162770	OCIAML5	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.29437699723915234	[116]	[258]	2	hSpCas9	negative selection	11142126
105044404	105044427	11	-	28162770	EOL1	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.47417719917941026	[495]	[362]	4	hSpCas9	negative selection	11311483
105044483	105044506	11	+	28162770	EOL1	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	1.9099503953575767	[148]	[294]	9	hSpCas9	negative selection	11311484
105044554	105044577	11	-	28162770	EOL1	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.6975416749209546	[782]	[668]	6	hSpCas9	negative selection	11311485
105041426	105041449	11	+	28162770	EOL1	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	-0.5117285240826484	[478]	[176]	-4	hSpCas9	negative selection	11311486
105041628	105041651	11	-	28162770	EOL1	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	-0.026817453178588885	[349]	[180]	0	hSpCas9	negative selection	11311487
105041496	105041519	11	-	28162770	EOL1	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	1.6716464717729418	[226]	[380]	9	hSpCas9	negative selection	11311488
105041664	105041687	11	+	28162770	EOL1	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	-0.7622943431698352	[131]	[40]	-5	hSpCas9	negative selection	11311489
105044391	105044414	11	-	28162770	EOL1	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	0.9610736475956485	[77]	[79]	8	hSpCas9	negative selection	11311490
105041535	105041558	11	-	28162770	EOL1	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	1.3911155714894605	[274]	[379]	9	hSpCas9	negative selection	11311491
105041702	105041725	11	-	28162770	EOL1	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	1.0685941411872413	[199]	[220]	8	hSpCas9	negative selection	11311492
105044404	105044427	11	-	28162770	MOLM13	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	1.3091083799037824	[402]	[721]	8	hSpCas9	negative selection	11480849
105044483	105044506	11	+	28162770	MOLM13	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	-0.3621856170131088	[175]	[98]	-2	hSpCas9	negative selection	11480850
105044554	105044577	11	-	28162770	MOLM13	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.82902494252444	[558]	[717]	6	hSpCas9	negative selection	11480851
105041426	105041449	11	+	28162770	MOLM13	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.11147961223644332	[433]	[338]	0	hSpCas9	negative selection	11480852
105041628	105041651	11	-	28162770	MOLM13	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	1.4419790598958864	[308]	[606]	9	hSpCas9	negative selection	11480853
105041496	105041519	11	-	28162770	MOLM13	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.9373746648457992	[155]	[215]	7	hSpCas9	negative selection	11480854
105041664	105041687	11	+	28162770	MOLM13	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	0.19703547125148568	[110]	[91]	1	hSpCas9	negative selection	11480855
105044391	105044414	11	-	28162770	MOLM13	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	1.5215273451466524	[65]	[136]	9	hSpCas9	negative selection	11480856
105041535	105041558	11	-	28162770	MOLM13	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	-0.04057498170253407	[302]	[212]	0	hSpCas9	negative selection	11480857
105041702	105041725	11	-	28162770	MOLM13	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.082599225659787	[191]	[146]	0	hSpCas9	negative selection	11480858
105044404	105044427	11	-	28162770	HEL	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	1.289340398513899	[335]	[525]	9	hSpCas9	negative selection	11650215
105044483	105044506	11	+	28162770	HEL	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	1.0088667307982542	[134]	[173]	8	hSpCas9	negative selection	11650216
105044554	105044577	11	-	28162770	HEL	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.7266400896093019	[500]	[530]	6	hSpCas9	negative selection	11650217
105041426	105041449	11	+	28162770	HEL	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.45009375405796104	[351]	[307]	4	hSpCas9	negative selection	11650218
105041628	105041651	11	-	28162770	HEL	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	1.2962150711708624	[280]	[441]	9	hSpCas9	negative selection	11650219
105041496	105041519	11	-	28162770	HEL	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.337884250471936	[209]	[169]	3	hSpCas9	negative selection	11650220
105041664	105041687	11	+	28162770	HEL	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	-0.47700041227373857	[112]	[51]	-3	hSpCas9	negative selection	11650221
105044391	105044414	11	-	28162770	HEL	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	1.1833072133630598	[54]	[79]	9	hSpCas9	negative selection	11650222
105041535	105041558	11	-	28162770	HEL	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.19835737113936885	[297]	[218]	1	hSpCas9	negative selection	11650223
105041702	105041725	11	-	28162770	HEL	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.9906621354206636	[175]	[223]	8	hSpCas9	negative selection	11650224
105044404	105044427	11	-	28162770	MV411	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.4104226552049317	[300]	[336]	3	hSpCas9	negative selection	11819581
105044483	105044506	11	+	28162770	MV411	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	0.573013422685282	[78]	[98]	5	hSpCas9	negative selection	11819582
105044554	105044577	11	-	28162770	MV411	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.3259298591020747	[464]	[490]	3	hSpCas9	negative selection	11819583
105041426	105041449	11	+	28162770	MV411	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.024183046934336372	[278]	[238]	0	hSpCas9	negative selection	11819584
105041628	105041651	11	-	28162770	MV411	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.7374884044784646	[177]	[249]	6	hSpCas9	negative selection	11819585
105041496	105041519	11	-	28162770	MV411	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.08873980476371704	[191]	[171]	0	hSpCas9	negative selection	11819586
105041664	105041687	11	+	28162770	MV411	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	1.1607259175894444	[59]	[112]	8	hSpCas9	negative selection	11819587
105044391	105044414	11	-	28162770	MV411	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-3.103059696301358	[50]	[4]	-9	hSpCas9	negative selection	11819588
105041535	105041558	11	-	28162770	MV411	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.7294060581806059	[178]	[249]	6	hSpCas9	negative selection	11819589
105041702	105041725	11	-	28162770	MV411	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	1.7387649793927014	[121]	[342]	9	hSpCas9	negative selection	11819590
105044404	105044427	11	-	28162770	MONOMAC1	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.8480510424689844	[188]	[389]	7	hSpCas9	negative selection	11988947
105044483	105044506	11	+	28162770	MONOMAC1	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	1.3302101558053152	[50]	[146]	9	hSpCas9	negative selection	11988948
105044554	105044577	11	-	28162770	MONOMAC1	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.4176729970556545	[319]	[489]	4	hSpCas9	negative selection	11988949
105041426	105041449	11	+	28162770	MONOMAC1	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.3651543460029443	[148]	[219]	3	hSpCas9	negative selection	11988950
105041628	105041651	11	-	28162770	MONOMAC1	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.8282742414696337	[112]	[229]	7	hSpCas9	negative selection	11988951
105041496	105041519	11	-	28162770	MONOMAC1	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.6564144895875044	[87]	[158]	6	hSpCas9	negative selection	11988952
105041664	105041687	11	+	28162770	MONOMAC1	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	0.5034028710815384	[39]	[64]	5	hSpCas9	negative selection	11988953
105044391	105044414	11	-	28162770	MONOMAC1	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-1.3225677291434126	[23]	[10]	-7	hSpCas9	negative selection	11988954
105041535	105041558	11	-	28162770	MONOMAC1	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	1.02708646235601	[118]	[277]	8	hSpCas9	negative selection	11988955
105041702	105041725	11	-	28162770	MONOMAC1	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.7144264783387889	[83]	[157]	6	hSpCas9	negative selection	11988956
105044404	105044427	11	-	28162770	OCIAML2	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	0.41689544549942614	[59]	[443]	4	hSpCas9	negative selection	12158313
105044483	105044506	11	+	28162770	OCIAML2	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	0.5293701747578388	[19]	[159]	5	hSpCas9	negative selection	12158314
105044554	105044577	11	-	28162770	OCIAML2	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.34699343226927004	[79]	[563]	3	hSpCas9	negative selection	12158315
105041426	105041449	11	+	28162770	OCIAML2	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	-0.26976111659158064	[81]	[376]	-2	hSpCas9	negative selection	12158316
105041628	105041651	11	-	28162770	OCIAML2	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.7846272299999133	[30]	[295]	7	hSpCas9	negative selection	12158317
105041496	105041519	11	-	28162770	OCIAML2	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.9023222726696678	[24]	[258]	8	hSpCas9	negative selection	12158318
105041664	105041687	11	+	28162770	OCIAML2	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	0.9525816054823827	[10]	[117]	8	hSpCas9	negative selection	12158319
105044391	105044414	11	-	28162770	OCIAML2	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	0.3069777534213909	[6]	[47]	3	hSpCas9	negative selection	12158320
105041535	105041558	11	-	28162770	OCIAML2	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	-0.14870173035479886	[33]	[169]	-1	hSpCas9	negative selection	12158321
105041702	105041725	11	-	28162770	OCIAML2	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	-0.11514917064377225	[33]	[173]	-1	hSpCas9	negative selection	12158322
105044404	105044427	11	-	28162770	OCIAML3	viability	CAGTTACCTGGCAGAGACGCTGG	CARD16	ENSG00000204397	1.1520601609492955	[78]	[529]	8	hSpCas9	negative selection	12327679
105044483	105044506	11	+	28162770	OCIAML3	viability	AACGGAGTCAATCAAAGCTCGGG	CARD16	ENSG00000204397	-0.009045139603006846	[37]	[113]	0	hSpCas9	negative selection	12327680
105044554	105044577	11	-	28162770	OCIAML3	viability	ACAGACAAGGGTGCTGAACCAGG	CARD16	ENSG00000204397	0.6768462699689297	[114]	[554]	6	hSpCas9	negative selection	12327681
105041426	105041449	11	+	28162770	OCIAML3	viability	GCAACTCTTTACCTAAACCTGGG	CARD16	ENSG00000204397	0.22444499061677164	[73]	[260]	2	hSpCas9	negative selection	12327682
105041628	105041651	11	-	28162770	OCIAML3	viability	GCTTTCTAGAAGACGCTCAAAGG	CARD16	ENSG00000204397	0.04644997298869662	[50]	[158]	0	hSpCas9	negative selection	12327683
105041496	105041519	11	-	28162770	OCIAML3	viability	ATTTTATTGAGCGGTTCTGGAGG	CARD16	ENSG00000204397	0.2918213397565257	[45]	[169]	2	hSpCas9	negative selection	12327684
105041664	105041687	11	+	28162770	OCIAML3	viability	GCCTTCTGGGCTTGAGCATGTGG	CARD16	ENSG00000204397	0.38461870888327	[16]	[66]	3	hSpCas9	negative selection	12327685
105044391	105044414	11	-	28162770	OCIAML3	viability	GAGACGCTGGGACTCTCAGCAGG	CARD16	ENSG00000204397	-1.6935433138750777	[14]	[13]	-8	hSpCas9	negative selection	12327686
105041535	105041558	11	-	28162770	OCIAML3	viability	CAGGCAGTTTTGAAATGCAGTGG	CARD16	ENSG00000204397	0.34683028720769304	[55]	[214]	3	hSpCas9	negative selection	12327687
105041702	105041725	11	-	28162770	OCIAML3	viability	TGCAGCTCTTCAGGCAGTGCAGG	CARD16	ENSG00000204397	0.38523379950903963	[34]	[137]	3	hSpCas9	negative selection	12327688