Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8573
• Symbol:CASK
• Description:calcium/calmodulin dependent serine protein kinase

DataSource: http://genomecrispr.dkfz.de/#!/results/CASK

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41660445	41660468	X	-	26472758	Jiyoye	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	1.3464213504267772	[96]	[185]	7	hSpCas9	negative selection	23669
41853129	41853152	X	-	26472758	Jiyoye	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.6412970954244285	[209]	[246]	5	hSpCas9	negative selection	23670
41561579	41561602	X	-	26472758	Jiyoye	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.8123313692707532	[292]	[387]	5	hSpCas9	negative selection	23671
41671508	41671531	X	+	26472758	Jiyoye	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	0.3131318915907356	[205]	[192]	2	hSpCas9	negative selection	23672
41636587	41636610	X	-	26472758	Jiyoye	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	-0.15432814639129389	[182]	[123]	-1	hSpCas9	negative selection	23673
41626668	41626691	X	+	26472758	Jiyoye	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	1.7325756683000408	[82]	[207]	8	hSpCas9	negative selection	23674
41626626	41626649	X	+	26472758	Jiyoye	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	-0.31944826843887386	[277]	[167]	-2	hSpCas9	negative selection	23675
41578433	41578456	X	+	26472758	Jiyoye	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.6042122285654273	[81]	[93]	4	hSpCas9	negative selection	23676
41553843	41553866	X	+	26472758	Jiyoye	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	2.055703011004496	[110]	[347]	8	hSpCas9	negative selection	23677
41542784	41542807	X	-	26472758	Jiyoye	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.28578027399121986	[284]	[261]	2	hSpCas9	negative selection	23678
41660445	41660468	X	-	26472758	KBM7	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.6522932377168342	[641,452]	[485,321]	7	hSpCas9	negative selection	214787
41853129	41853152	X	-	26472758	KBM7	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.5753058523010988	[898,1073]	[629,763]	6	hSpCas9	negative selection	214788
41561579	41561602	X	-	26472758	KBM7	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.7560894328314456	[946,810]	[782,617]	8	hSpCas9	negative selection	214789
41671508	41671531	X	+	26472758	KBM7	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-0.24558389949433357	[753,709]	[397,194]	-2	hSpCas9	negative selection	214790
41636587	41636610	X	-	26472758	KBM7	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.31542880227946324	[607,485]	[299,333]	3	hSpCas9	negative selection	214791
41626668	41626691	X	+	26472758	KBM7	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.8044839644020125	[838,658]	[600,618]	8	hSpCas9	negative selection	214792
41626626	41626649	X	+	26472758	KBM7	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.5025010093739134	[784,625]	[479,454]	5	hSpCas9	negative selection	214793
41578433	41578456	X	+	26472758	KBM7	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.6343122085244535	[298,279]	[237,187]	7	hSpCas9	negative selection	214794
41553843	41553866	X	+	26472758	KBM7	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.4423364692897145	[790,872]	[492,575]	5	hSpCas9	negative selection	214795
41542784	41542807	X	-	26472758	KBM7	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.508403009653215	[1163,1049]	[945,555]	5	hSpCas9	negative selection	214796
41660445	41660468	X	-	26472758	Raji	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	1.0134073871645857	[221]	[103]	8	hSpCas9	negative selection	405905
41853129	41853152	X	-	26472758	Raji	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.3666263620450192	[507]	[151]	3	hSpCas9	negative selection	405906
41561579	41561602	X	-	26472758	Raji	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.8886114297158484	[397]	[170]	7	hSpCas9	negative selection	405907
41671508	41671531	X	+	26472758	Raji	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-0.18539821385424643	[293]	[59]	-1	hSpCas9	negative selection	405908
41636587	41636610	X	-	26472758	Raji	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.7118988335161562	[341]	[129]	6	hSpCas9	negative selection	405909
41626668	41626691	X	+	26472758	Raji	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.7649913379265216	[354]	[139]	7	hSpCas9	negative selection	405910
41626626	41626649	X	+	26472758	Raji	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.30808088561072844	[535]	[153]	3	hSpCas9	negative selection	405911
41578433	41578456	X	+	26472758	Raji	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	1.0885245081222839	[153]	[75]	8	hSpCas9	negative selection	405912
41553843	41553866	X	+	26472758	Raji	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	1.0535166633948636	[381]	[183]	8	hSpCas9	negative selection	405913
41542784	41542807	X	-	26472758	Raji	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	-0.33691855841043883	[663]	[121]	-3	hSpCas9	negative selection	405914
41660445	41660468	X	-	26472758	K562	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.7024083721298378	[363]	[499]	6	hSpCas9	negative selection	597023
41853129	41853152	X	-	26472758	K562	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.5778720858239417	[772]	[973]	5	hSpCas9	negative selection	597024
41561579	41561602	X	-	26472758	K562	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.8483821903176588	[703]	[1069]	7	hSpCas9	negative selection	597025
41671508	41671531	X	+	26472758	K562	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-0.3678019800991331	[560]	[366]	-2	hSpCas9	negative selection	597026
41636587	41636610	X	-	26472758	K562	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.5644472896383274	[607]	[758]	4	hSpCas9	negative selection	597027
41626668	41626691	X	+	26472758	K562	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.5189750033954601	[581]	[703]	4	hSpCas9	negative selection	597028
41626626	41626649	X	+	26472758	K562	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	1.426055481432255	[517]	[1174]	9	hSpCas9	negative selection	597029
41578433	41578456	X	+	26472758	K562	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.6216541942329061	[260]	[338]	5	hSpCas9	negative selection	597030
41553843	41553866	X	+	26472758	K562	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.7170525282847267	[533]	[740]	6	hSpCas9	negative selection	597031
41542784	41542807	X	-	26472758	K562	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.7855934957452808	[891]	[1297]	6	hSpCas9	negative selection	597032
41578430	41578453	X	+	26627737	DLD1	viability	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	0.2518156425299558	[140]	[70,52,35]	2	hSpCas9	negative selection	845632
41609996	41610019	X	-	26627737	DLD1	viability	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.7258341613779367	[875]	[246,730,400]	7	hSpCas9	negative selection	845633
41660428	41660451	X	+	26627737	DLD1	viability	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.6278366089507224	[913]	[653,337,342]	6	hSpCas9	negative selection	845634
41745523	41745546	X	-	26627737	DLD1	viability	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	1.0118204185225876	[229]	[175,132,127]	8	hSpCas9	negative selection	845639
41853114	41853137	X	-	26627737	DLD1	viability	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	1.2182452294203627	[165]	[94,63,189]	9	hSpCas9	negative selection	845640
41922968	41922991	X	+	26627737	DLD1	viability	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.04768705288678199	[913]	[89,622,150]	0	hSpCas9	negative selection	845641
41578430	41578453	X	+	26627737	GBM cells	viability after 5 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	0.6240540336551019	[146]	[119,122]	8	hSpCas9	negative selection	927947
41609996	41610019	X	-	26627737	GBM cells	viability after 5 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.14972197838622026	[315]	[166,208]	2	hSpCas9	negative selection	927948
41660428	41660451	X	+	26627737	GBM cells	viability after 5 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.2053705610106078	[599]	[362,378]	3	hSpCas9	negative selection	927949
41745523	41745546	X	-	26627737	GBM cells	viability after 5 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.536343795500977	[116]	[87,93]	7	hSpCas9	negative selection	927954
41853114	41853137	X	-	26627737	GBM cells	viability after 5 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.9368817250847061	[149]	[114,192]	9	hSpCas9	negative selection	927955
41922968	41922991	X	+	26627737	GBM cells	viability after 5 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.0257064055334556	[380]	[239,175]	0	hSpCas9	negative selection	927956
41578430	41578453	X	+	26627737	GBM cells	viability after 13 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.005086625360309904	[146]	[68,87]	0	hSpCas9	negative selection	1010262
41609996	41610019	X	-	26627737	GBM cells	viability after 13 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.5657953979836134	[315]	[314,203]	7	hSpCas9	negative selection	1010263
41660428	41660451	X	+	26627737	GBM cells	viability after 13 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.3262556744246785	[599]	[368,439]	4	hSpCas9	negative selection	1010264
41745523	41745546	X	-	26627737	GBM cells	viability after 13 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.02082601661762684	[116]	[43,80]	0	hSpCas9	negative selection	1010269
41853114	41853137	X	-	26627737	GBM cells	viability after 13 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.8820324014999074	[149]	[208,101]	8	hSpCas9	negative selection	1010270
41922968	41922991	X	+	26627737	GBM cells	viability after 13 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.3293423666890222	[380]	[190,142]	-4	hSpCas9	negative selection	1010271
41578430	41578453	X	+	26627737	GBM cells	viability after 21 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	0.903382685757621	[146]	[163,135]	8	hSpCas9	negative selection	1092577
41609996	41610019	X	-	26627737	GBM cells	viability after 21 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.5866853590947847	[315]	[261,253]	6	hSpCas9	negative selection	1092578
41660428	41660451	X	+	26627737	GBM cells	viability after 21 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.5655007061324999	[599]	[519,447]	6	hSpCas9	negative selection	1092579
41745523	41745546	X	-	26627737	GBM cells	viability after 21 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	-0.14408391343649352	[116]	[56,57]	-1	hSpCas9	negative selection	1092584
41853114	41853137	X	-	26627737	GBM cells	viability after 21 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.5780730031777465	[149]	[117,124]	6	hSpCas9	negative selection	1092585
41922968	41922991	X	+	26627737	GBM cells	viability after 21 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.41202473152203867	[380]	[153,156]	-4	hSpCas9	negative selection	1092586
41578430	41578453	X	+	26627737	RPE1	viability after 9 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.4091088762359246	[479]	[103,124]	-3	hSpCas9	negative selection	1174892
41609996	41610019	X	-	26627737	RPE1	viability after 9 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.41760679775123155	[1325]	[550,558]	3	hSpCas9	negative selection	1174893
41660428	41660451	X	+	26627737	RPE1	viability after 9 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	1.7391858283043535	[530]	[330,843]	8	hSpCas9	negative selection	1174894
41745523	41745546	X	-	26627737	RPE1	viability after 9 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.9855288935576448	[411]	[233,282]	6	hSpCas9	negative selection	1174899
41853114	41853137	X	-	26627737	RPE1	viability after 9 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	1.691889988287558	[273]	[284,266]	8	hSpCas9	negative selection	1174900
41922968	41922991	X	+	26627737	RPE1	viability after 9 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.1426065511009892	[1486]	[312,561]	-1	hSpCas9	negative selection	1174901
41578430	41578453	X	+	26627737	RPE1	viability after 12 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.33472137246396294	[479]	[93,110]	-2	hSpCas9	negative selection	1257207
41609996	41610019	X	-	26627737	RPE1	viability after 12 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.5149301526252895	[1325]	[493,524]	3	hSpCas9	negative selection	1257208
41660428	41660451	X	+	26627737	RPE1	viability after 12 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	2.173627921054662	[530]	[596,692]	9	hSpCas9	negative selection	1257209
41745523	41745546	X	-	26627737	RPE1	viability after 12 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.3988706772476769	[411]	[177,111]	2	hSpCas9	negative selection	1257214
41853114	41853137	X	-	26627737	RPE1	viability after 12 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	1.5598205019171423	[273]	[183,251]	8	hSpCas9	negative selection	1257215
41922968	41922991	X	+	26627737	RPE1	viability after 12 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.08798011664327188	[1486]	[428,419]	0	hSpCas9	negative selection	1257216
41578430	41578453	X	+	26627737	RPE1	viability after 15 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.7008902728770664	[479]	[137,30]	-4	hSpCas9	negative selection	1339522
41609996	41610019	X	-	26627737	RPE1	viability after 15 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	1.1901830138842646	[1325]	[973,741]	6	hSpCas9	negative selection	1339523
41660428	41660451	X	+	26627737	RPE1	viability after 15 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	2.239508427037751	[530]	[605,808]	9	hSpCas9	negative selection	1339524
41745523	41745546	X	-	26627737	RPE1	viability after 15 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.43741684469885767	[411]	[223,93]	3	hSpCas9	negative selection	1339529
41853114	41853137	X	-	26627737	RPE1	viability after 15 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.9185850408939622	[273]	[173,119]	5	hSpCas9	negative selection	1339530
41922968	41922991	X	+	26627737	RPE1	viability after 15 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.5507486162786784	[1486]	[418,159]	-3	hSpCas9	negative selection	1339531
41578430	41578453	X	+	26627737	RPE1	viability after 18 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-1.0433107845617235	[479]	[43,82]	-6	hSpCas9	negative selection	1421837
41609996	41610019	X	-	26627737	RPE1	viability after 18 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.8663700572867091	[1325]	[677,624]	5	hSpCas9	negative selection	1421838
41660428	41660451	X	+	26627737	RPE1	viability after 18 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	2.4953878493888593	[530]	[648,977]	9	hSpCas9	negative selection	1421839
41745523	41745546	X	-	26627737	RPE1	viability after 18 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.3745164935209716	[411]	[191,92]	2	hSpCas9	negative selection	1421844
41853114	41853137	X	-	26627737	RPE1	viability after 18 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	1.120683233148587	[273]	[110,213]	6	hSpCas9	negative selection	1421845
41922968	41922991	X	+	26627737	RPE1	viability after 18 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.9401804260997753	[1486]	[256,157]	-5	hSpCas9	negative selection	1421846
41578430	41578453	X	+	26627737	HeLa	viability after 8 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	0.09046570490687839	[305]	[308,68,87]	0	hSpCas9	negative selection	1504152
41609996	41610019	X	-	26627737	HeLa	viability after 8 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.49072236705296873	[542]	[492,347,199]	4	hSpCas9	negative selection	1504153
41660428	41660451	X	+	26627737	HeLa	viability after 8 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	-0.30750043561845497	[720]	[325,263,190]	-3	hSpCas9	negative selection	1504154
41745523	41745546	X	-	26627737	HeLa	viability after 8 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.10772731842119537	[278]	[239,8,164]	1	hSpCas9	negative selection	1504159
41853114	41853137	X	-	26627737	HeLa	viability after 8 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	-0.7325538914416247	[568]	[214,118,128]	-6	hSpCas9	negative selection	1504160
41922968	41922991	X	+	26627737	HeLa	viability after 8 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.2575508822962645	[443]	[236,237,219]	2	hSpCas9	negative selection	1504161
41578430	41578453	X	+	26627737	HeLa	viability after 12 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	0.0835218858457174	[305]	[150,147,101]	0	hSpCas9	negative selection	1586467
41609996	41610019	X	-	26627737	HeLa	viability after 12 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.5080870665291912	[542]	[279,283,395]	4	hSpCas9	negative selection	1586468
41660428	41660451	X	+	26627737	HeLa	viability after 12 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.094690768324454	[720]	[439,148,386]	0	hSpCas9	negative selection	1586469
41745523	41745546	X	-	26627737	HeLa	viability after 12 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	-0.09430581111773079	[278]	[129,66,131]	-1	hSpCas9	negative selection	1586474
41853114	41853137	X	-	26627737	HeLa	viability after 12 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	-1.3670309735407749	[568]	[61,134,70]	-8	hSpCas9	negative selection	1586475
41922968	41922991	X	+	26627737	HeLa	viability after 12 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.5133555450190983	[443]	[261,230,295]	4	hSpCas9	negative selection	1586476
41578430	41578453	X	+	26627737	HeLa	viability after 15 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	0.38692711214917186	[305]	[155,154,178]	3	hSpCas9	negative selection	1668782
41609996	41610019	X	-	26627737	HeLa	viability after 15 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.9637917143618162	[542]	[368,436,492]	7	hSpCas9	negative selection	1668783
41660428	41660451	X	+	26627737	HeLa	viability after 15 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.1618301318852564	[720]	[336,101,563]	1	hSpCas9	negative selection	1668784
41745523	41745546	X	-	26627737	HeLa	viability after 15 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	-0.6399452795487246	[278]	[82,44,91]	-5	hSpCas9	negative selection	1668789
41853114	41853137	X	-	26627737	HeLa	viability after 15 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	-1.0215522190748982	[568]	[70,131,141]	-7	hSpCas9	negative selection	1668790
41922968	41922991	X	+	26627737	HeLa	viability after 15 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.5626822342505634	[443]	[64,320,429]	4	hSpCas9	negative selection	1668791
41578430	41578453	X	+	26627737	HeLa	viability after 18 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	0.3998632365658082	[305]	[106,128,178]	3	hSpCas9	negative selection	1751097
41609996	41610019	X	-	26627737	HeLa	viability after 18 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.941140373325658	[542]	[239,354,492]	7	hSpCas9	negative selection	1751098
41660428	41660451	X	+	26627737	HeLa	viability after 18 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.15394141298222874	[720]	[222,83,563]	1	hSpCas9	negative selection	1751099
41745523	41745546	X	-	26627737	HeLa	viability after 18 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	-0.6676761421218704	[278]	[53,35,91]	-5	hSpCas9	negative selection	1751104
41853114	41853137	X	-	26627737	HeLa	viability after 18 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	-1.011694086297771	[568]	[46,111,141]	-7	hSpCas9	negative selection	1751105
41922968	41922991	X	+	26627737	HeLa	viability after 18 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.5664282392568144	[443]	[39,271,429]	4	hSpCas9	negative selection	1751106
41578430	41578453	X	+	26627737	HCT116	viability after 6 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	2.3936618005319343	[229]	[160,205]	9	hSpCas9	negative selection	1833412
41609996	41610019	X	-	26627737	HCT116	viability after 6 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	1.8561406242620426	[915]	[336,622]	8	hSpCas9	negative selection	1833413
41660428	41660451	X	+	26627737	HCT116	viability after 6 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.2951805838013988	[1414]	[426,187]	1	hSpCas9	negative selection	1833414
41745523	41745546	X	-	26627737	HCT116	viability after 6 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	3.488852984569168	[133]	[46,340]	9	hSpCas9	negative selection	1833419
41853114	41853137	X	-	26627737	HCT116	viability after 6 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.07026122809405294	[488]	[217,4]	0	hSpCas9	negative selection	1833420
41922968	41922991	X	+	26627737	HCT116	viability after 6 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.565285090640178	[1181]	[292,264]	3	hSpCas9	negative selection	1833421
41578430	41578453	X	+	26627737	HCT116	viability after 8 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.8195109724810969	[292]	[56,138,77]	-7	hSpCas9	negative selection	1915727
41609996	41610019	X	-	26627737	HCT116	viability after 8 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.9472031612266336	[252]	[295,168,340]	8	hSpCas9	negative selection	1915728
41660428	41660451	X	+	26627737	HCT116	viability after 8 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.028797078660076858	[920]	[547,345,657]	0	hSpCas9	negative selection	1915729
41745523	41745546	X	-	26627737	HCT116	viability after 8 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	1.018538549962425	[159]	[190,244,100]	8	hSpCas9	negative selection	1915734
41853114	41853137	X	-	26627737	HCT116	viability after 8 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.8492820917783557	[108]	[156,101,66]	7	hSpCas9	negative selection	1915735
41922968	41922991	X	+	26627737	HCT116	viability after 8 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	1.058889198944196	[255]	[330,314,236]	8	hSpCas9	negative selection	1915736
41578430	41578453	X	+	26627737	HCT116	viability after 9 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	1.535233191375491	[229]	[53,275]	8	hSpCas9	negative selection	1998042
41609996	41610019	X	-	26627737	HCT116	viability after 9 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.4136367955421206	[915]	[279,361]	3	hSpCas9	negative selection	1998043
41660428	41660451	X	+	26627737	HCT116	viability after 9 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.25550236725228026	[1414]	[526,390]	2	hSpCas9	negative selection	1998044
41745523	41745546	X	-	26627737	HCT116	viability after 9 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	1.3516855636863994	[133]	[135,55]	8	hSpCas9	negative selection	1998049
41853114	41853137	X	-	26627737	HCT116	viability after 9 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	-0.28711239266032157	[488]	[125,91]	-2	hSpCas9	negative selection	1998050
41922968	41922991	X	+	26627737	HCT116	viability after 9 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	1.2646809595606197	[1181]	[549,922]	8	hSpCas9	negative selection	1998051
41578430	41578453	X	+	26627737	HCT116	viability after 12 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-1.134194431548098	[292]	[74,68,65]	-8	hSpCas9	negative selection	2080357
41609996	41610019	X	-	26627737	HCT116	viability after 12 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	1.3662549421896908	[252]	[253,379,402]	9	hSpCas9	negative selection	2080358
41660428	41660451	X	+	26627737	HCT116	viability after 12 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	-0.03609902258905251	[920]	[347,428,648]	0	hSpCas9	negative selection	2080359
41745523	41745546	X	-	26627737	HCT116	viability after 12 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.7089529771812557	[159]	[106,136,170]	6	hSpCas9	negative selection	2080364
41853114	41853137	X	-	26627737	HCT116	viability after 12 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	1.3215749075273742	[108]	[161,148,116]	8	hSpCas9	negative selection	2080365
41922968	41922991	X	+	26627737	HCT116	viability after 12 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	1.3852719947748966	[255]	[127,271,671]	9	hSpCas9	negative selection	2080366
41578430	41578453	X	+	26627737	HCT116	viability after 15 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.529569575866672	[292]	[165,95,93]	-5	hSpCas9	negative selection	2162672
41609996	41610019	X	-	26627737	HCT116	viability after 15 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	1.041905804014902	[252]	[269,164,456]	8	hSpCas9	negative selection	2162673
41660428	41660451	X	+	26627737	HCT116	viability after 15 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.031090231713992944	[920]	[826,436,393]	0	hSpCas9	negative selection	2162674
41745523	41745546	X	-	26627737	HCT116	viability after 15 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	1.545337608781514	[159]	[210,266,318]	9	hSpCas9	negative selection	2162679
41853114	41853137	X	-	26627737	HCT116	viability after 15 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.8930423884712051	[108]	[177,122,55]	7	hSpCas9	negative selection	2162680
41922968	41922991	X	+	26627737	HCT116	viability after 15 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	1.5480801794288954	[255]	[494,480,322]	9	hSpCas9	negative selection	2162681
41578430	41578453	X	+	26627737	HCT116	viability after 18 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-1.1702622490497407	[292]	[72,82,29]	-8	hSpCas9	negative selection	2244987
41609996	41610019	X	-	26627737	HCT116	viability after 18 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	1.925493883614885	[252]	[429,357,619]	9	hSpCas9	negative selection	2244988
41660428	41660451	X	+	26627737	HCT116	viability after 18 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	-0.5597830027669144	[920]	[225,334,344]	-5	hSpCas9	negative selection	2244989
41745523	41745546	X	-	26627737	HCT116	viability after 18 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	1.2457251866278924	[159]	[91,291,157]	8	hSpCas9	negative selection	2244994
41853114	41853137	X	-	26627737	HCT116	viability after 18 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	1.1405786820052455	[108]	[90,113,144]	8	hSpCas9	negative selection	2244995
41922968	41922991	X	+	26627737	HCT116	viability after 18 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	1.5221985981055632	[255]	[258,398,407]	9	hSpCas9	negative selection	2244996
41787202	41787225	X	-	24336569	HL60	viability	TTGGAGACATATAGCTCAGATGG	CASK	ENSG00000147044	0.4844400642765752	[507]	[1503]	4	hSpCas9	negative selection	2254446
41787220	41787243	X	+	24336569	HL60	viability	TCCAATAACTCTACAATGTGTGG	CASK	ENSG00000147044	-0.2071722288633424	[1479]	[2712]	-2	hSpCas9	negative selection	2254447
41853111	41853134	X	+	24336569	HL60	viability	TTACCTTCTGTACTTAACCCTGG	CASK	ENSG00000147044	0.504700145302013	[399]	[1200]	4	hSpCas9	negative selection	2254448
41853128	41853151	X	-	24336569	HL60	viability	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	0.17303362325041197	[564]	[1347]	1	hSpCas9	negative selection	2254449
41853182	41853205	X	-	24336569	HL60	viability	GATGTATCAACAGAGAAACTGGG	CASK	ENSG00000147044	0.9381728023925555	[601]	[2440]	7	hSpCas9	negative selection	2254450
41853200	41853223	X	+	24336569	HL60	viability	ACATCGTCGTACAACACTGAAGG	CASK	ENSG00000147044	0.6591719322687817	[1687]	[5640]	5	hSpCas9	negative selection	2254451
41922933	41922956	X	-	24336569	HL60	viability	TACGAGCTGTGCGAGGTGATCGG	CASK	ENSG00000147044	0.37169522400319766	[942]	[2581]	3	hSpCas9	negative selection	2254452
41922940	41922963	X	-	24336569	HL60	viability	GGATGTGTACGAGCTGTGCGAGG	CASK	ENSG00000147044	-0.4360490829976098	[591]	[925]	-4	hSpCas9	negative selection	2254453
41922961	41922984	X	-	24336569	HL60	viability	CGACGACGACGTGCTGTTCGAGG	CASK	ENSG00000147044	0.4851927455730147	[845]	[2505]	4	hSpCas9	negative selection	2254454
41922968	41922991	X	+	24336569	HL60	viability	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.038578287775719755	[579]	[1194]	0	hSpCas9	negative selection	2254455
41787202	41787225	X	-	24336569	KBM7	viability	TTGGAGACATATAGCTCAGATGG	CASK	ENSG00000147044	0.5161702771817565	[402]	[1571]	5	hSpCas9	negative selection	2321623
41787220	41787243	X	+	24336569	KBM7	viability	TCCAATAACTCTACAATGTGTGG	CASK	ENSG00000147044	0.6886970238170499	[587]	[2584]	6	hSpCas9	negative selection	2321624
41853111	41853134	X	+	24336569	KBM7	viability	TTACCTTCTGTACTTAACCCTGG	CASK	ENSG00000147044	0.8674152322039417	[291]	[1452]	7	hSpCas9	negative selection	2321625
41853128	41853151	X	-	24336569	KBM7	viability	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	1.003157237554482	[468]	[2563]	8	hSpCas9	negative selection	2321626
41853182	41853205	X	-	24336569	KBM7	viability	GATGTATCAACAGAGAAACTGGG	CASK	ENSG00000147044	-0.058603993856234826	[781]	[2047]	0	hSpCas9	negative selection	2321627
41853200	41853223	X	+	24336569	KBM7	viability	ACATCGTCGTACAACACTGAAGG	CASK	ENSG00000147044	0.6056646359383062	[1442]	[5988]	5	hSpCas9	negative selection	2321628
41922933	41922956	X	-	24336569	KBM7	viability	TACGAGCTGTGCGAGGTGATCGG	CASK	ENSG00000147044	1.398077226423687	[376]	[2709]	9	hSpCas9	negative selection	2321629
41922940	41922963	X	-	24336569	KBM7	viability	GGATGTGTACGAGCTGTGCGAGG	CASK	ENSG00000147044	0.48759088253926264	[585]	[2240]	4	hSpCas9	negative selection	2321630
41922961	41922984	X	-	24336569	KBM7	viability	CGACGACGACGTGCTGTTCGAGG	CASK	ENSG00000147044	0.05996899060575778	[771]	[2194]	0	hSpCas9	negative selection	2321631
41922968	41922991	X	+	24336569	KBM7	viability	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.11153142632752905	[487]	[1437]	1	hSpCas9	negative selection	2321632
41745041	41745064	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTTTCGCTCTTGTTGCCCAAG	CASK	ENSG00000147044	-0.7837275452001344	[95,22]	[7,5]	-4	dCas9-VP64	positive selection	2394496
41923138	41923161	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAAGGCGCCGCAGTCTCTGGG	CASK	ENSG00000147044	1.9496502447773114	[43,21]	[29,24]	6	dCas9-VP64	positive selection	2397321
41923115	41923138	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GACGCTCGAGTGGGGCCGCGAGG	CASK	ENSG00000147044	2.7835957231488404	[11,18]	[43,1]	8	dCas9-VP64	positive selection	2397322
41923162	41923185	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCAGGCGACCGCCCCGGCGCGG	CASK	ENSG00000147044	0.7311413523720649	[106,14]	[21,20]	3	dCas9-VP64	positive selection	2397323
41643045	41643068	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATCAGATGGTTGTAGTTGTGTGG	CASK	ENSG00000147044	1.2754949334465935	[38,164]	[76,30]	5	dCas9-VP64	positive selection	2398967
41702550	41702573	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTTGGGAGGCCAAGGCGGGCAG	CASK	ENSG00000147044	0.09588317305989913	[114,12]	[10,18]	0	dCas9-VP64	positive selection	2411117
41809086	41809109	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCAGGAAGCTCAAACTGGGTGG	CASK	ENSG00000147044	-1.2834902115453883	[110,41]	[9,2]	-7	dCas9-VP64	positive selection	2421810
41591498	41591521	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTTTGTCTCCCAGG	CASK	ENSG00000147044	-0.7059861923714007	[63,29]	[9,1]	-4	dCas9-VP64	positive selection	2425246
41688802	41688825	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATTTCCTAAAGTTCAGTGTTGG	CASK	ENSG00000147044	-1.8700807746527133	[123,114]	[4,8]	-8	dCas9-VP64	positive selection	2437592
41688807	41688830	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAACCAACACTGAACTTTAGG	CASK	ENSG00000147044	0.08253237280740278	[367,139]	[96,16]	0	dCas9-VP64	positive selection	2437593
41688825	41688848	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGAGCTTAAAGTTGTTCCATGG	CASK	ENSG00000147044	-0.5694546930362289	[98,118]	[21,8]	-3	dCas9-VP64	positive selection	2437594
41715576	41715599	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCATTGCACTCCAGCCCAG	CASK	ENSG00000147044	3.359380449218091	[189,5]	[417,3]	8	dCas9-VP64	positive selection	2446591
41723957	41723980	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATCGTGCAAACAAAGGTTACTGG	CASK	ENSG00000147044	0.6983518125572359	[71,476]	[27,175]	3	dCas9-VP64	positive selection	2462940
41724034	41724057	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATTTCTGTAGTGGGAGGAAGTGG	CASK	ENSG00000147044	1.3717853812345953	[147,169]	[168,6]	5	dCas9-VP64	positive selection	2462941
41723950	41723973	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGTCAATCGTGCAAACAAAGG	CASK	ENSG00000147044	1.3106252011748158	[36,30]	[22,13]	5	dCas9-VP64	positive selection	2462942
41785034	41785057	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGTTCTGTTGCCCAGGCTAG	CASK	ENSG00000147044	-0.6863317618464422	[59,137]	[14,10]	-3	dCas9-VP64	positive selection	2464078
41908121	41908144	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTTTGGGAGGCTGAAGGAG	CASK	ENSG00000147044	6.35516198632701	[126,1064]	[8429,13566]	9	dCas9-VP64	positive selection	2467062
41612264	41612287	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCCTGGCCGCCCATCGTCTGAG	CASK	ENSG00000147044	-0.0329650900813252	[388,64]	[87,4]	0	dCas9-VP64	positive selection	2468136
41597903	41597926	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAAGCAGTCTGCCCACCTTGG	CASK	ENSG00000147044	0.20576949065447114	[17,35]	[6,5]	1	dCas9-VP64	positive selection	2476400
41745041	41745064	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTTTCGCTCTTGTTGCCCAAG	CASK	ENSG00000147044	-0.16320683952806103	[88,58]	[29,12]	-1	dCas9-VP64	positive selection	2489751
41923138	41923161	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAAGGCGCCGCAGTCTCTGGG	CASK	ENSG00000147044	-0.5939130043169374	[55,265]	[39,28]	-6	dCas9-VP64	positive selection	2492576
41923115	41923138	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GACGCTCGAGTGGGGCCGCGAGG	CASK	ENSG00000147044	2.150702755340605	[19,12]	[7,37]	8	dCas9-VP64	positive selection	2492577
41923162	41923185	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCAGGCGACCGCCCCGGCGCGG	CASK	ENSG00000147044	-0.8401195735108602	[148,101]	[22,21]	-7	dCas9-VP64	positive selection	2492578
41643045	41643068	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATCAGATGGTTGTAGTTGTGTGG	CASK	ENSG00000147044	0.6191055033012778	[76,91]	[39,43]	4	dCas9-VP64	positive selection	2494222
41702550	41702573	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTTGGGAGGCCAAGGCGGGCAG	CASK	ENSG00000147044	3.077269363618506	[19,18]	[13,93]	9	dCas9-VP64	positive selection	2506372
41809086	41809109	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCAGGAAGCTCAAACTGGGTGG	CASK	ENSG00000147044	-0.4862249962475964	[248,57]	[62,10]	-5	dCas9-VP64	positive selection	2517065
41591498	41591521	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTTTGTCTCCCAGG	CASK	ENSG00000147044	1.0992483033047402	[46,34]	[13,41]	7	dCas9-VP64	positive selection	2520501
41688802	41688825	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATTTCCTAAAGTTCAGTGTTGG	CASK	ENSG00000147044	-0.7341314212610015	[244,678]	[50,125]	-7	dCas9-VP64	positive selection	2532847
41688807	41688830	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAACCAACACTGAACTTTAGG	CASK	ENSG00000147044	0.2913635705661465	[93,189]	[27,81]	2	dCas9-VP64	positive selection	2532848
41688825	41688848	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGAGCTTAAAGTTGTTCCATGG	CASK	ENSG00000147044	-0.17249511251201569	[126,149]	[31,46]	-2	dCas9-VP64	positive selection	2532849
41715576	41715599	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCATTGCACTCCAGCCCAG	CASK	ENSG00000147044	0.626840615877442	[158,168]	[52,109]	4	dCas9-VP64	positive selection	2541846
41723957	41723980	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATCGTGCAAACAAAGGTTACTGG	CASK	ENSG00000147044	2.027430443556602	[76,56]	[57,118]	8	dCas9-VP64	positive selection	2558195
41724034	41724057	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATTTCTGTAGTGGGAGGAAGTGG	CASK	ENSG00000147044	0.4195266635259312	[93,127]	[37,57]	3	dCas9-VP64	positive selection	2558196
41723950	41723973	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGTCAATCGTGCAAACAAAGG	CASK	ENSG00000147044	-0.8711363501415567	[236,104]	[43,17]	-7	dCas9-VP64	positive selection	2558197
41785034	41785057	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGTTCTGTTGCCCAGGCTAG	CASK	ENSG00000147044	-0.6931781766025115	[37,108]	[16,10]	-6	dCas9-VP64	positive selection	2559333
41908121	41908144	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTTTGGGAGGCTGAAGGAG	CASK	ENSG00000147044	6.970706058095935	[220,255]	[14367,5508]	9	dCas9-VP64	positive selection	2562317
41612264	41612287	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCCTGGCCGCCCATCGTCTGAG	CASK	ENSG00000147044	-0.3398026399627511	[257,143]	[72,31]	-3	dCas9-VP64	positive selection	2563391
41597903	41597926	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAAGCAGTCTGCCCACCTTGG	CASK	ENSG00000147044	0.6530020702020014	[53,174]	[34,79]	5	dCas9-VP64	positive selection	2571655
41922962	41922985	X	+	27013184	SW480	treatment with recombinant TRAIL	CTCGAACAGCACGTCGTCGTCGG	CASK	ENSG00000147044	1.2124738110114626	[1,1]	[1,1]	6	hSpCas9	positive selection	2961749
41922968	41922991	X	+	27013184	SW480	treatment with recombinant TRAIL	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.8672203513364594	[390,420]	[110,73]	-4	hSpCas9	positive selection	2961750
41853182	41853205	X	-	27013184	SW480	treatment with recombinant TRAIL	GATGTATCAACAGAGAAACTGGG	CASK	ENSG00000147044	-0.7620559066875825	[422,363]	[113,81]	-3	hSpCas9	positive selection	2961751
41589551	41589574	X	-	27013184	SW480	treatment with recombinant TRAIL	CAAAGTCTTCACCACAAATCAGG	CASK	ENSG00000147044	-1.1459303762173585	[326,451]	[52,105]	-5	hSpCas9	positive selection	2961752
41665311	41665334	X	+	27013184	SW480	treatment with recombinant TRAIL	CTTTCCTTGGTTCCGTAAAAAGG	CASK	ENSG00000147044	0.32020655537089215	[30,64]	[29,17]	1	hSpCas9	positive selection	2961753
41853183	41853206	X	-	27013184	SW480	treatment with recombinant TRAIL	CGATGTATCAACAGAGAAACTGG	CASK	ENSG00000147044	0.7770239600239555	[113,176]	[55,175]	4	hSpCas9	positive selection	2961754
41665380	41665403	X	+	27013184	SW480	treatment with recombinant TRAIL	ACGTCTACAGGCTTTCCGTAAGG	CASK	ENSG00000147044	2.2487528071778247	[1208,906]	[1690,2917]	8	hSpCas9	positive selection	2961755
41665416	41665439	X	+	27013184	SW480	treatment with recombinant TRAIL	ACTTCTGGTGCCATAAAATGAGG	CASK	ENSG00000147044	-2.448279506209759	[122,483]	[11,37]	-8	hSpCas9	positive selection	2961756
41787220	41787243	X	+	27013184	SW480	treatment with recombinant TRAIL	TCCAATAACTCTACAATGTGTGG	CASK	ENSG00000147044	1.6723453556647987	[41,82]	[61,113]	7	hSpCas9	positive selection	2961757
41922985	41923008	X	+	27013184	SW480	treatment with recombinant TRAIL	CCATGGTCCGGAGGGGATAGCGG	CASK	ENSG00000147044	2.057267074301991	[161,199]	[144,573]	8	hSpCas9	positive selection	2961758
41787246	41787269	X	+	27013184	SW480	treatment with recombinant TRAIL	TTTCAGCATATGACAGATACTGG	CASK	ENSG00000147044	1.7353916635037923	[179,142]	[129,382]	7	hSpCas9	positive selection	2961759
41853111	41853134	X	+	27013184	SW480	treatment with recombinant TRAIL	TTACCTTCTGTACTTAACCCTGG	CASK	ENSG00000147044	1.597351431730094	[179,116]	[159,250]	7	hSpCas9	positive selection	2961760
41787188	41787211	X	-	27013184	SW480	treatment with recombinant TRAIL	CTCAGATGGAATGCTTTACATGG	CASK	ENSG00000147044	-2.2370285486242714	[240,269]	[7,44]	-8	hSpCas9	positive selection	2961761
41787221	41787244	X	-	27013184	SW480	treatment with recombinant TRAIL	TCCACACATTGTAGAGTTATTGG	CASK	ENSG00000147044	-5.379616410514194	[135,260]	[1,1]	-9	hSpCas9	positive selection	2961762
41787272	41787295	X	-	27013184	SW480	treatment with recombinant TRAIL	TTGTTTTACAGATCTAAAGCGGG	CASK	ENSG00000147044	-2.7151188051477275	[447,410]	[10,52]	-8	hSpCas9	positive selection	2961763
41787273	41787296	X	-	27013184	SW480	treatment with recombinant TRAIL	TTTGTTTTACAGATCTAAAGCGG	CASK	ENSG00000147044	1.5038371063981177	[320,471]	[358,644]	7	hSpCas9	positive selection	2961764
41853128	41853151	X	+	27013184	SW480	treatment with recombinant TRAIL	CCCTGGACTTGATGTGAACTTGG	CASK	ENSG00000147044	-4.6980192424862395	[130,161]	[1,2]	-9	hSpCas9	positive selection	2961765
41589525	41589548	X	+	27013184	SW480	treatment with recombinant TRAIL	CTCTGTACTGCATCGCTTGGAGG	CASK	ENSG00000147044	-1.9417135740764635	[237,267]	[12,49]	-7	hSpCas9	positive selection	2961766
41589540	41589563	X	+	27013184	SW480	treatment with recombinant TRAIL	CTTGGAGGATTCCTGATTTGTGG	CASK	ENSG00000147044	-0.16048546414029685	[160,109]	[20,98]	0	hSpCas9	positive selection	2961767
41853200	41853223	X	+	27013184	SW480	treatment with recombinant TRAIL	ACATCGTCGTACAACACTGAAGG	CASK	ENSG00000147044	-0.19330818937709626	[55,100]	[32,22]	-1	hSpCas9	positive selection	2961768
41853201	41853224	X	+	27013184	SW480	treatment with recombinant TRAIL	CATCGTCGTACAACACTGAAGGG	CASK	ENSG00000147044	-1.861999216885931	[303,282]	[3,78]	-7	hSpCas9	positive selection	2961769
41853114	41853137	X	-	27013184	SW480	treatment with recombinant TRAIL	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	-1.3982842274892715	[124,281]	[32,30]	-6	hSpCas9	positive selection	2961770
41665373	41665396	X	-	27013184	SW480	treatment with recombinant TRAIL	GAAAGCCTGTAGACGTCTGGGGG	CASK	ENSG00000147044	-0.4258168202493604	[684,471]	[166,219]	-2	hSpCas9	positive selection	2961771
41665374	41665397	X	-	27013184	SW480	treatment with recombinant TRAIL	GGAAAGCCTGTAGACGTCTGGGG	CASK	ENSG00000147044	-0.3700627795875603	[154,196]	[20,110]	-2	hSpCas9	positive selection	2961772
41665375	41665398	X	-	27013184	SW480	treatment with recombinant TRAIL	CGGAAAGCCTGTAGACGTCTGGG	CASK	ENSG00000147044	-1.7136143096285221	[6,24]	[1,1]	-7	hSpCas9	positive selection	2961773
41665376	41665399	X	-	27013184	SW480	treatment with recombinant TRAIL	ACGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	-1.3480111097255123	[2510,124]	[46,517]	-6	hSpCas9	positive selection	2961774
41853128	41853151	X	-	27013184	SW480	treatment with recombinant TRAIL	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	-0.17054517440026773	[75,114]	[30,42]	0	hSpCas9	positive selection	2961775
41561579	41561602	X	-	27013184	SW480	treatment with recombinant TRAIL	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.6229889715103222	[178,185]	[85,170]	3	hSpCas9	positive selection	2961776
41561594	41561617	X	-	27013184	SW480	treatment with recombinant TRAIL	AGAAATCAATGGCATCAGTGTGG	CASK	ENSG00000147044	0.01541303608497957	[306,289]	[106,163]	0	hSpCas9	positive selection	2961777
41853129	41853152	X	-	27013184	SW480	treatment with recombinant TRAIL	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	-0.4027578102272085	[301,441]	[47,220]	-2	hSpCas9	positive selection	2961778
41853202	41853225	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATCGTCGTACAACACTGAAGGG	CASK	ENSG00000147044	0.16397826491201675	[3,3]	[3,2]	3	hSpCas9	positive selection	2976380
41853128	41853151	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	-0.1885074509715225	[4,4]	[4,1]	-3	hSpCas9	positive selection	2976381
41671494	41671517	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTGCCTCAAAAGAAAACTCGG	CASK	ENSG00000147044	0.261711341191621	[5,5]	[5,5]	5	hSpCas9	positive selection	2976382
41922940	41922963	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATGTGTACGAGCTGTGCGAGG	CASK	ENSG00000147044	-0.2762985573742127	[3,3]	[4,0]	-4	hSpCas9	positive selection	2976383
41853202	41853225	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATCGTCGTACAACACTGAAGGG	CASK	ENSG00000147044	0.18875453242132317	[3,3]	[3,2]	3	hSpCas9	positive selection	3044238
41853128	41853151	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	0.14812504694546652	[4,4]	[4,2]	2	hSpCas9	positive selection	3044239
41671494	41671517	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTGCCTCAAAAGAAAACTCGG	CASK	ENSG00000147044	0.16463597265664998	[5,5]	[4,3]	3	hSpCas9	positive selection	3044240
41922940	41922963	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATGTGTACGAGCTGTGCGAGG	CASK	ENSG00000147044	-0.40896762337356757	[3,3]	[2,0]	-6	hSpCas9	positive selection	3044241
41636577	41636600		-	24336571	A375	resistance to PLX after 7 days	CAATGCAAGGAGGAAACTAAAGG	CASK	ENSG00000147044	0.2650943316276403	[13,13]	[17,15]	7	hSpCas9	positive selection	3160686
41636605	41636628		-	24336571	A375	resistance to PLX after 7 days	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	-0.022381312664234265	[32,34]	[33,32]	0	hSpCas9	positive selection	3160687
41626624	41626647		+	24336571	A375	resistance to PLX after 7 days	GAGAAATCTGGTAACTCTTCAGG	CASK	ENSG00000147044	0.06657779850789958	[18,18]	[18,20]	2	hSpCas9	positive selection	3160688
41626603	41626626		-	24336571	A375	resistance to PLX after 7 days	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.15057885151458272	[108,101]	[117,114]	5	hSpCas9	positive selection	3160689
41636577	41636600		-	24336571	A375	resistance to PLX after 14 days	CAATGCAAGGAGGAAACTAAAGG	CASK	ENSG00000147044	-0.21438001858211148	[17,12]	[6,4]	-2	hSpCas9	positive selection	3218479
41636605	41636628		-	24336571	A375	resistance to PLX after 14 days	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	-0.5514035038187252	[31,34]	[8,11]	-6	hSpCas9	positive selection	3218480
41626624	41626647		+	24336571	A375	resistance to PLX after 14 days	GAGAAATCTGGTAACTCTTCAGG	CASK	ENSG00000147044	0.12327745198931517	[24,25]	[12,12]	1	hSpCas9	positive selection	3218481
41626603	41626626		-	24336571	A375	resistance to PLX after 14 days	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	3.8877660372220535	[108,111]	[808,723]	9	hSpCas9	positive selection	3218482
41636577	41636600		-	24336571	A375	viability after 7 days	CAATGCAAGGAGGAAACTAAAGG	CASK	ENSG00000147044	-0.8545083456981052	[26]	[13,13]	-8	hSpCas9	negative selection	3276272
41636605	41636628		-	24336571	A375	viability after 7 days	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.3894217711916388	[26]	[32,34]	6	hSpCas9	negative selection	3276273
41626624	41626647		+	24336571	A375	viability after 7 days	GAGAAATCTGGTAACTCTTCAGG	CASK	ENSG00000147044	-0.003325922592236963	[19]	[18,18]	0	hSpCas9	negative selection	3276274
41626603	41626626		-	24336571	A375	viability after 7 days	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.8145186220821627	[62]	[108,101]	9	hSpCas9	negative selection	3276275
41636577	41636600		-	24336571	A375	viability after 14 days	CAATGCAAGGAGGAAACTAAAGG	CASK	ENSG00000147044	-0.664961191672757	[26]	[17,12]	-7	hSpCas9	negative selection	3334065
41636605	41636628		-	24336571	A375	viability after 14 days	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.39114892880729824	[26]	[31,34]	5	hSpCas9	negative selection	3334066
41626624	41626647		+	24336571	A375	viability after 14 days	GAGAAATCTGGTAACTCTTCAGG	CASK	ENSG00000147044	0.43389203128800624	[19]	[24,25]	5	hSpCas9	negative selection	3334067
41626603	41626626		-	24336571	A375	viability after 14 days	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.8944649074444713	[62]	[108,111]	9	hSpCas9	negative selection	3334068
41610011	41610034	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	-0.6025231916086654	[201,262]	[0,0]	-4	hSpCas9	positive selection	3341098
41626603	41626626	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.7294318858138065	[577,528]	[0,10]	3	hSpCas9	positive selection	3341099
41626594	41626617	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.7728257814032353	[95,82]	[0,0]	4	hSpCas9	positive selection	3341100
41609978	41610001	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.4841407749553118	[213,213]	[0,0]	-3	hSpCas9	positive selection	3360346
41636606	41636629	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	-1.316320976047487	[380,380]	[0,0]	-8	hSpCas9	positive selection	3360347
41636605	41636628	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.5430806937797126	[104,104]	[0,0]	2	hSpCas9	positive selection	3360348
41853201	41853224	X	+	26780180	HT29	viability (Avana library 4 designs)	CATCGTCGTACAACACTGAAGGG	CASK	ENSG00000147044	0.842691885937866	[]	[]	3	hSpCas9	negative selection	3412661
41853128	41853151	X	-	26780180	HT29	viability (Avana library 4 designs)	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	-0.403100039749602	[]	[]	-6	hSpCas9	negative selection	3412662
41671494	41671517	X	-	26780180	HT29	viability (Avana library 4 designs)	CCTTGCCTCAAAAGAAAACTCGG	CASK	ENSG00000147044	-0.0943328495896796	[]	[]	-1	hSpCas9	negative selection	3412663
41922940	41922963	X	-	26780180	HT29	viability (Avana library 4 designs)	GGATGTGTACGAGCTGTGCGAGG	CASK	ENSG00000147044	0.945920870120989	[]	[]	3	hSpCas9	negative selection	3412664
41922940	41922963	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGTGTACGAGCTGTGCGAGG	CASK	ENSG00000147044	8.46123597482039	[]	[]	9	hSpCas9	negative selection	3488237
41853201	41853224	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATCGTCGTACAACACTGAAGGG	CASK	ENSG00000147044	-5.73638594950867	[]	[]	-6	hSpCas9	negative selection	3488238
41671494	41671517	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGCCTCAAAAGAAAACTCGG	CASK	ENSG00000147044	-1.04331080081254	[]	[]	-1	hSpCas9	negative selection	3488239
41853128	41853151	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	3.9234810186434	[]	[]	6	hSpCas9	negative selection	3488240
41660429	41660452	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCATGTACCTTAAGCCATGGG	CASK	ENSG00000147044	4.49184381092214	[]	[]	7	hSpCas9	negative selection	3488241
41853111	41853134	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTACCTTCTGTACTTAACCCTGG	CASK	ENSG00000147044	-5.09962446201919	[]	[]	-5	hSpCas9	negative selection	3488242
41922940	41922963	X	-	26780180	A375	viability (Avana lentiGuide)	GGATGTGTACGAGCTGTGCGAGG	CASK	ENSG00000147044	-5.70708824111246	[]	[]	-8	hSpCas9	negative selection	3596896
41853201	41853224	X	+	26780180	A375	viability (Avana lentiGuide)	CATCGTCGTACAACACTGAAGGG	CASK	ENSG00000147044	-2.08110265771256	[]	[]	-4	hSpCas9	negative selection	3596897
41671494	41671517	X	-	26780180	A375	viability (Avana lentiGuide)	CCTTGCCTCAAAAGAAAACTCGG	CASK	ENSG00000147044	-3.61645017815697	[]	[]	-6	hSpCas9	negative selection	3596898
41853128	41853151	X	-	26780180	A375	viability (Avana lentiGuide)	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	-6.85274164641034	[]	[]	-9	hSpCas9	negative selection	3596899
41660429	41660452	X	+	26780180	A375	viability (Avana lentiGuide)	GCTCATGTACCTTAAGCCATGGG	CASK	ENSG00000147044	-2.651968686213	[]	[]	-5	hSpCas9	negative selection	3596900
41853111	41853134	X	+	26780180	A375	viability (Avana lentiGuide)	TTACCTTCTGTACTTAACCCTGG	CASK	ENSG00000147044	-2.36573069089245	[]	[]	-4	hSpCas9	negative selection	3596901
41922940	41922963	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGTGTACGAGCTGTGCGAGG	CASK	ENSG00000147044	0.4460137563134208	[4]	[6,6]	9	hSpCas9	positive selection	3705555
41853201	41853224	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATCGTCGTACAACACTGAAGGG	CASK	ENSG00000147044	0.10698315248422854	[4]	[5,5]	2	hSpCas9	positive selection	3705556
41671494	41671517	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGCCTCAAAAGAAAACTCGG	CASK	ENSG00000147044	-0.3860991486239549	[6]	[5,3]	-5	hSpCas9	positive selection	3705557
41853128	41853151	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	0.17012808213231068	[5]	[5,6]	4	hSpCas9	positive selection	3705558
41660429	41660452	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCATGTACCTTAAGCCATGGG	CASK	ENSG00000147044	0.14893096986228413	[4]	[5,4]	4	hSpCas9	positive selection	3705559
41853111	41853134	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACCTTCTGTACTTAACCCTGG	CASK	ENSG00000147044	-0.32476452537099987	[7]	[5,5]	-5	hSpCas9	positive selection	3705560
41922940	41922963	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGTGTACGAGCTGTGCGAGG	CASK	ENSG00000147044	0.2806049624558029	[5]	[5,4]	7	hSpCas9	positive selection	3814162
41853201	41853224	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATCGTCGTACAACACTGAAGGG	CASK	ENSG00000147044	0.2252740549158991	[5]	[4,4]	6	hSpCas9	positive selection	3814163
41671494	41671517	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGCCTCAAAAGAAAACTCGG	CASK	ENSG00000147044	0.27111379593316437	[7]	[7,6]	7	hSpCas9	positive selection	3814164
41853128	41853151	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAAGTTCACATCAAGTCCAGGG	CASK	ENSG00000147044	0.4174235333444369	[5]	[6,6]	9	hSpCas9	positive selection	3814165
41660429	41660452	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCATGTACCTTAAGCCATGGG	CASK	ENSG00000147044	-0.004734072722979793	[5]	[4,3]	0	hSpCas9	positive selection	3814166
41853111	41853134	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACCTTCTGTACTTAACCCTGG	CASK	ENSG00000147044	0.24690932056426784	[8]	[8,8]	6	hSpCas9	positive selection	3814167
41626594	41626617	X	+	26780180	A375	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.686685515081918	[]	[]	2	hSpCas9	negative selection	3922465
41636605	41636628	X	-	26780180	A375	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.24209244023689	[]	[]	0	hSpCas9	negative selection	3922466
41610011	41610034	X	-	26780180	A375	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.281301254620646	[]	[]	0	hSpCas9	negative selection	3922467
41636606	41636629	X	+	26780180	A375	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.976440165575942	[]	[]	4	hSpCas9	negative selection	3922468
41609978	41610001	X	+	26780180	A375	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	1.6788705498354	[]	[]	9	hSpCas9	negative selection	3922469
41626603	41626626	X	-	26780180	A375	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	-0.121103508950238	[]	[]	-4	hSpCas9	negative selection	3922470
41626594	41626617	X	+	26780180	HT29	viability (GeCKOv2 library)	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	1.5081517122486	[]	[]	7	hSpCas9	negative selection	4030431
41636605	41636628	X	-	26780180	HT29	viability (GeCKOv2 library)	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.516931938547182	[]	[]	1	hSpCas9	negative selection	4030432
41610011	41610034	X	-	26780180	HT29	viability (GeCKOv2 library)	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.3357041609655	[]	[]	0	hSpCas9	negative selection	4030433
41636606	41636629	X	+	26780180	HT29	viability (GeCKOv2 library)	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.400231339484902	[]	[]	1	hSpCas9	negative selection	4030434
41609978	41610001	X	+	26780180	HT29	viability (GeCKOv2 library)	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	2.4441388329124	[]	[]	9	hSpCas9	negative selection	4030435
41626603	41626626	X	-	26780180	HT29	viability (GeCKOv2 library)	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	-0.0500170828576712	[]	[]	-1	hSpCas9	negative selection	4030436
41636577	41636600	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATGCAAGGAGGAAACTAAAGG	CASK	ENSG00000147044	0.08460486615274466	[3]	[2,2]	2	hSpCas9	positive selection	4188778
41636605	41636628	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.021562787512393156	[5]	[3,3]	0	hSpCas9	positive selection	4188779
41626624	41626647	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGAAATCTGGTAACTCTTCAGG	CASK	ENSG00000147044	0.2125071344923012	[4]	[2,3]	5	hSpCas9	positive selection	4188780
41626603	41626626	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.7325649787245977	[6]	[5,9]	9	hSpCas9	positive selection	4188781
41636577	41636600	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATGCAAGGAGGAAACTAAAGG	CASK	ENSG00000147044	0.3166374728242261	[4]	[1,3,5,0]	2	hSpCas9	positive selection	4252800
41636605	41636628	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	1.0669158359952018	[4]	[4,5,3,4]	7	hSpCas9	positive selection	4252801
41626624	41626647	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGAAATCTGGTAACTCTTCAGG	CASK	ENSG00000147044	0.669305632361378	[3]	[4,4,4,0]	4	hSpCas9	positive selection	4252802
41626603	41626626	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	1.0209413039941162	[5]	[4,6,5,4]	7	hSpCas9	positive selection	4252803
41610011	41610034	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.3898274806142046	[3]	[4,3]	7	hSpCas9	positive selection	4260986
41626603	41626626	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.34487000319818073	[4]	[5,4]	7	hSpCas9	positive selection	4260987
41626594	41626617	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.28198654269791634	[2]	[2,0]	-5	hSpCas9	positive selection	4260988
41609978	41610001	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.6789499484122019	[3]	[2,0]	-9	hSpCas9	positive selection	4325264
41636606	41636629	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.09491560410164424	[3]	[3,2]	2	hSpCas9	positive selection	4325265
41636605	41636628	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	-0.010300348658539002	[2]	[2,1]	0	hSpCas9	positive selection	4325266
41578506	41578528	X	+	27760321	OCIAML3	viability	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	-0.05537746449774439	[298,231]	[210,181]	0	hSpCas9	negative selection	4385751
41586942	41586964	X	-	27760321	OCIAML3	viability	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	1.4948281194491488	[228,178]	[331,595]	9	hSpCas9	negative selection	4385752
41610011	41610033	X	-	27760321	OCIAML3	viability	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.7035128103425536	[372,289]	[354,502]	8	hSpCas9	negative selection	4385753
41665376	41665398	X	-	27760321	OCIAML3	viability	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	-0.4246663972160081	[618,557]	[286,414]	-4	hSpCas9	negative selection	4385754
41671478	41671500	X	-	27760321	OCIAML3	viability	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	0.6917443368759121	[437,343]	[425,574]	7	hSpCas9	negative selection	4385755
41578506	41578528	X	+	27760321	OCIAML2	viability	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	0.2342839954626183	[298,231]	[145,388]	3	hSpCas9	negative selection	4469214
41586942	41586964	X	-	27760321	OCIAML2	viability	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	1.0725446538366101	[228,178]	[238,483]	9	hSpCas9	negative selection	4469215
41610011	41610033	X	-	27760321	OCIAML2	viability	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.12000494866503025	[372,289]	[231,364]	1	hSpCas9	negative selection	4469216
41665376	41665398	X	-	27760321	OCIAML2	viability	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	0.49707850143526944	[618,557]	[612,747]	6	hSpCas9	negative selection	4469217
41671478	41671500	X	-	27760321	OCIAML2	viability	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	0.9611889853460068	[437,343]	[666,538]	9	hSpCas9	negative selection	4469218
41578506	41578528	X	+	27760321	MV411	viability	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	0.34187254319978777	[298,231]	[78,432]	2	hSpCas9	negative selection	4552677
41586942	41586964	X	-	27760321	MV411	viability	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	0.5799964656424801	[228,178]	[45,430]	4	hSpCas9	negative selection	4552678
41610011	41610033	X	-	27760321	MV411	viability	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	-0.00034380910538744924	[372,289]	[187,260]	0	hSpCas9	negative selection	4552679
41665376	41665398	X	-	27760321	MV411	viability	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	0.001215130828738975	[618,557]	[269,565]	0	hSpCas9	negative selection	4552680
41671478	41671500	X	-	27760321	MV411	viability	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	0.3883837772828669	[437,343]	[223,502]	2	hSpCas9	negative selection	4552681
41578506	41578528	X	+	27760321	HL60	viability	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	-0.14600794748420776	[298,231]	[181,207]	-2	hSpCas9	negative selection	4636140
41586942	41586964	X	-	27760321	HL60	viability	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	0.11452403759021035	[228,178]	[201,154]	1	hSpCas9	negative selection	4636141
41610011	41610033	X	-	27760321	HL60	viability	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.07141933408547418	[372,289]	[250,315]	0	hSpCas9	negative selection	4636142
41665376	41665398	X	-	27760321	HL60	viability	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	1.0550369323420505	[618,557]	[1109,878]	9	hSpCas9	negative selection	4636143
41671478	41671500	X	-	27760321	HL60	viability	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	0.0029677184316094785	[437,343]	[365,266]	0	hSpCas9	negative selection	4636144
41578506	41578528	X	+	27760321	HT1080	viability	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	0.709146566802668	[231,180]	[91,180]	4	hSpCas9	negative selection	4719603
41586942	41586964	X	-	27760321	HT1080	viability	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	0.9263335059055943	[178,139]	[136,102]	5	hSpCas9	negative selection	4719604
41610011	41610033	X	-	27760321	HT1080	viability	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	-1.128244950130091	[289,226]	[17,78]	-4	hSpCas9	negative selection	4719605
41665376	41665398	X	-	27760321	HT1080	viability	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	0.1149890529535359	[557,435]	[212,215]	0	hSpCas9	negative selection	4719606
41671478	41671500	X	-	27760321	HT1080	viability	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	1.1281448286352442	[343,268]	[222,314]	6	hSpCas9	negative selection	4719607
41578506	41578528	X	+	27760321	HT29	viability after 7 days	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	-0.6169243535783193	[231,180]	[143,262,109]	-7	hSpCas9	negative selection	4803066
41586942	41586964	X	-	27760321	HT29	viability after 7 days	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	0.12373266694800478	[178,139]	[412,152,133]	2	hSpCas9	negative selection	4803067
41610011	41610033	X	-	27760321	HT29	viability after 7 days	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	-0.3258309138538137	[289,226]	[352,291,165]	-5	hSpCas9	negative selection	4803068
41665376	41665398	X	-	27760321	HT29	viability after 7 days	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	-0.10842838846050884	[557,435]	[608,425,739]	-1	hSpCas9	negative selection	4803069
41671478	41671500	X	-	27760321	HT29	viability after 7 days	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	0.7334201270366036	[343,268]	[813,694,483]	9	hSpCas9	negative selection	4803070
41578506	41578528	X	+	27760321	HT29	viability after 25 days	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	-0.36780798077570287	[231,180]	[37,314,206]	-4	hSpCas9	negative selection	4886529
41586942	41586964	X	-	27760321	HT29	viability after 25 days	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	1.108186976732582	[178,139]	[529,399,221]	9	hSpCas9	negative selection	4886530
41610011	41610033	X	-	27760321	HT29	viability after 25 days	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.38107260016470845	[289,226]	[221,531,412]	4	hSpCas9	negative selection	4886531
41665376	41665398	X	-	27760321	HT29	viability after 25 days	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	0.06470315249882708	[557,435]	[524,594,673]	0	hSpCas9	negative selection	4886532
41671478	41671500	X	-	27760321	HT29	viability after 25 days	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	0.4079682551692385	[343,268]	[398,394,619]	4	hSpCas9	negative selection	4886533
41578506	41578528	X	+	27760321	HT29	viability after 22 days	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	0.20582832493951442	[231,180]	[240,194,391]	2	hSpCas9	negative selection	4969992
41586942	41586964	X	-	27760321	HT29	viability after 22 days	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	1.2029001162119994	[178,139]	[690,396,175]	9	hSpCas9	negative selection	4969993
41610011	41610033	X	-	27760321	HT29	viability after 22 days	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	-0.23792636647261456	[289,226]	[65,383,315]	-2	hSpCas9	negative selection	4969994
41665376	41665398	X	-	27760321	HT29	viability after 22 days	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	0.1608072085371003	[557,435]	[452,537,943]	1	hSpCas9	negative selection	4969995
41671478	41671500	X	-	27760321	HT29	viability after 22 days	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	0.4375946607588553	[343,268]	[558,363,514]	5	hSpCas9	negative selection	4969996
41578506	41578528	X	+	27760321	HT29	viability after 19 days	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	-0.33188565047725516	[231,180]	[183,233,145]	-3	hSpCas9	negative selection	5053455
41586942	41586964	X	-	27760321	HT29	viability after 19 days	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	-0.35200486556994726	[178,139]	[257,45,136]	-3	hSpCas9	negative selection	5053456
41610011	41610033	X	-	27760321	HT29	viability after 19 days	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.6131268639373283	[289,226]	[413,444,491]	6	hSpCas9	negative selection	5053457
41665376	41665398	X	-	27760321	HT29	viability after 19 days	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	0.3566037422893883	[557,435]	[623,922,628]	3	hSpCas9	negative selection	5053458
41671478	41671500	X	-	27760321	HT29	viability after 19 days	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	1.018556805107399	[343,268]	[595,536,974]	9	hSpCas9	negative selection	5053459
41578506	41578528	X	+	27760321	HT29	viability after 16 days	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	0.20685749628601724	[231,180]	[157,443,182]	2	hSpCas9	negative selection	5136918
41586942	41586964	X	-	27760321	HT29	viability after 16 days	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	0.4067318748112083	[178,139]	[369,211,140]	4	hSpCas9	negative selection	5136919
41610011	41610033	X	-	27760321	HT29	viability after 16 days	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.06811707783278498	[289,226]	[386,249,281]	0	hSpCas9	negative selection	5136920
41665376	41665398	X	-	27760321	HT29	viability after 16 days	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	0.024976229309511433	[557,435]	[358,594,722]	0	hSpCas9	negative selection	5136921
41671478	41671500	X	-	27760321	HT29	viability after 16 days	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	0.8086963220991881	[343,268]	[754,472,591]	8	hSpCas9	negative selection	5136922
41578506	41578528	X	+	27760321	HT29	viability after 13 days	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	-0.04952691056060288	[231,180]	[240,249,204]	0	hSpCas9	negative selection	5220381
41586942	41586964	X	-	27760321	HT29	viability after 13 days	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	0.3824853422961364	[178,139]	[269,252,202]	5	hSpCas9	negative selection	5220382
41610011	41610033	X	-	27760321	HT29	viability after 13 days	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	-0.06489444003254674	[289,226]	[257,276,322]	-1	hSpCas9	negative selection	5220383
41665376	41665398	X	-	27760321	HT29	viability after 13 days	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	-0.14366856988038956	[557,435]	[402,588,570]	-2	hSpCas9	negative selection	5220384
41671478	41671500	X	-	27760321	HT29	viability after 13 days	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	1.03872081986291	[343,268]	[979,769,457]	9	hSpCas9	negative selection	5220385
41578506	41578528	X	+	27760321	HT29	viability after 10 days	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	0.21420408444558825	[231,180]	[303,492,109]	3	hSpCas9	negative selection	5303844
41586942	41586964	X	-	27760321	HT29	viability after 10 days	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	0.4696671794703998	[178,139]	[430,338,63]	6	hSpCas9	negative selection	5303845
41610011	41610033	X	-	27760321	HT29	viability after 10 days	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.06962964595062399	[289,226]	[325,218,464]	0	hSpCas9	negative selection	5303846
41665376	41665398	X	-	27760321	HT29	viability after 10 days	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	0.01625914113849497	[557,435]	[468,663,747]	0	hSpCas9	negative selection	5303847
41671478	41671500	X	-	27760321	HT29	viability after 10 days	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	0.6912398613133462	[343,268]	[636,732,489]	8	hSpCas9	negative selection	5303848
41578506	41578528	X	+	27760321	MOLM13	viability	ACGTCGTGAGTCTGAAGTAAGG	CASK	ENSG00000147044	0.17121817064829814	[298,231]	[113,212]	1	hSpCas9	negative selection	5387307
41586942	41586964	X	-	27760321	MOLM13	viability	CCTGAGAATAACGACGCAAAGG	CASK	ENSG00000147044	0.33756294984835433	[228,178]	[171,120]	2	hSpCas9	negative selection	5387308
41610011	41610033	X	-	27760321	MOLM13	viability	CCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.057460553334354014	[372,289]	[229,161]	0	hSpCas9	negative selection	5387309
41665376	41665398	X	-	27760321	MOLM13	viability	CGGAAAGCCTGTAGACGTCTGG	CASK	ENSG00000147044	0.5258793112677204	[618,557]	[361,575]	3	hSpCas9	negative selection	5387310
41671478	41671500	X	-	27760321	MOLM13	viability	ACTCGGCACCTGTTAAACTTGG	CASK	ENSG00000147044	1.1339820490434271	[437,343]	[447,508]	7	hSpCas9	negative selection	5387311
41923015	41923038	X	+	27661255	K562	viability	GTGGAGGGCTTCGAAAACGGGGG	CASK	ENSG00000147044	-0.09036960760770762	[1570,1550]	[1306,1055]	-3	dCas9-KRAB	negative selection	5468175
41923046	41923069	X	-	27661255	K562	viability	GGGCTGGGCACTGAGCTCTTGGG	CASK	ENSG00000147044	0.37131605796704203	[23,22]	[26,21]	9	dCas9-KRAB	negative selection	5468176
41923066	41923089	X	-	27661255	K562	viability	GAGGGGAGGAGGCGATCCCGGGG	CASK	ENSG00000147044	0.200638586680713	[356,512]	[379,410]	7	dCas9-KRAB	negative selection	5468177
41923080	41923103	X	-	27661255	K562	viability	GGCTCGCGGGTCCTGAGGGGAGG	CASK	ENSG00000147044	0.11069152912155755	[297,386]	[286,299]	4	dCas9-KRAB	negative selection	5468178
41923083	41923106	X	-	27661255	K562	viability	GAGGGCTCGCGGGTCCTGAGGGG	CASK	ENSG00000147044	0.1775752964265095	[990,1090]	[1055,838]	6	dCas9-KRAB	negative selection	5468179
41610011	41610034	X	-	27260156	BXPC3	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.3813439823738576	[822]	[960,1042,1164,1358]	7	hSpCas9	negative selection	5533446
41626603	41626626	X	-	27260156	BXPC3	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.3102380632264927	[1846]	[2178,2131,2378,2982]	6	hSpCas9	negative selection	5533447
41626594	41626617	X	+	27260156	BXPC3	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.33840109983611605	[371]	[542,430,459,531]	7	hSpCas9	negative selection	5533448
41609978	41610001	X	+	27260156	BXPC3	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.027257236189972	[588]	[613,508,633,775]	0	hSpCas9	negative selection	5597724
41636606	41636629	X	+	27260156	BXPC3	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.3562075017633356	[889]	[1007,1179,1423,1165]	7	hSpCas9	negative selection	5597725
41636605	41636628	X	-	27260156	BXPC3	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.1927837628607948	[401]	[430,501,598,379]	4	hSpCas9	negative selection	5597726
41610011	41610034	X	-	27260156	A673	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.4828517367639362	[822]	[1259,1325,1646,1266]	9	hSpCas9	negative selection	5654697
41626603	41626626	X	-	27260156	A673	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.24780658445588988	[1846]	[2831,2597,2464,2659]	6	hSpCas9	negative selection	5654698
41626594	41626617	X	+	27260156	A673	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.3210642539623664	[371]	[610,597,553,467]	7	hSpCas9	negative selection	5654699
41609978	41610001	X	+	27260156	A673	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.13542514665947092	[588]	[655,556,590,781]	-3	hSpCas9	negative selection	5718975
41636606	41636629	X	+	27260156	A673	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.1590061095836487	[889]	[1248,1048,1209,1276]	4	hSpCas9	negative selection	5718976
41636605	41636628	X	-	27260156	A673	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.1750859232962449	[401]	[606,482,530,567]	4	hSpCas9	negative selection	5718977
41610011	41610034	X	-	27260156	A375	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.8036359039647571	[822]	[1721,1999,1774,1298]	9	hSpCas9	negative selection	5775948
41626603	41626626	X	-	27260156	A375	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.4369918135338955	[1846]	[3165,3244,3028,2346]	6	hSpCas9	negative selection	5775949
41626594	41626617	X	+	27260156	A375	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.20646981168926273	[371]	[354,605,379,656]	3	hSpCas9	negative selection	5775950
41609978	41610001	X	+	27260156	A375	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.07239230572342026	[588]	[688,757,815,641]	1	hSpCas9	negative selection	5840226
41636606	41636629	X	+	27260156	A375	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.3323443210185403	[889]	[1152,1596,1560,995]	5	hSpCas9	negative selection	5840227
41636605	41636628	X	-	27260156	A375	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.13867797497948256	[401]	[580,632,450,427]	2	hSpCas9	negative selection	5840228
41610011	41610034	X	-	27260156	COLO741	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.4892250136720828	[822]	[1697,1335,1413]	8	hSpCas9	negative selection	5897199
41626603	41626626	X	-	27260156	COLO741	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.282825201895079	[1846]	[3026,3159,2463]	6	hSpCas9	negative selection	5897200
41626594	41626617	X	+	27260156	COLO741	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.19219202456861173	[371]	[668,616,365]	4	hSpCas9	negative selection	5897201
41609978	41610001	X	+	27260156	COLO741	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.37202380982105543	[588]	[642,630,481]	-7	hSpCas9	negative selection	5961477
41636606	41636629	X	+	27260156	COLO741	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	-0.07108470980325932	[889]	[1216,1065,980]	-1	hSpCas9	negative selection	5961478
41636605	41636628	X	-	27260156	COLO741	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	-0.06560245413297594	[401]	[538,510,429]	-1	hSpCas9	negative selection	5961479
41610011	41610034	X	-	27260156	CAL120	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.4068083646934535	[822]	[1890,1077,1186]	6	hSpCas9	negative selection	6018450
41626603	41626626	X	-	27260156	CAL120	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.40331393086096123	[1846]	[3737,2672,2815]	6	hSpCas9	negative selection	6018451
41626594	41626617	X	+	27260156	CAL120	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.42841002688823926	[371]	[536,488,825]	6	hSpCas9	negative selection	6018452
41609978	41610001	X	+	27260156	CAL120	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.3009840286067243	[588]	[585,702,495]	-4	hSpCas9	negative selection	6082728
41636606	41636629	X	+	27260156	CAL120	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.4872599516636401	[889]	[2121,1264,1358]	7	hSpCas9	negative selection	6082729
41636605	41636628	X	-	27260156	CAL120	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.2833914386262445	[401]	[528,608,674]	4	hSpCas9	negative selection	6082730
41610011	41610034	X	-	27260156	CADOES1	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.39580824763502953	[822]	[842,975,860,1361]	6	hSpCas9	negative selection	6139701
41626603	41626626	X	-	27260156	CADOES1	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.2286829576796381	[1846]	[1987,1857,1942,2271]	4	hSpCas9	negative selection	6139702
41626594	41626617	X	+	27260156	CADOES1	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.03343558779557926	[371]	[372,302,364,309]	0	hSpCas9	negative selection	6139703
41609978	41610001	X	+	27260156	CADOES1	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.29021980975041906	[588]	[497,430,408,453]	-5	hSpCas9	negative selection	6203979
41636606	41636629	X	+	27260156	CADOES1	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.4916329670637075	[889]	[1236,1159,946,1316]	7	hSpCas9	negative selection	6203980
41636605	41636628	X	-	27260156	CADOES1	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.4739981855929971	[401]	[406,758,571,332]	7	hSpCas9	negative selection	6203981
41610011	41610034	X	-	27260156	EWS502	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.50470440346622	[822]	[1107,1180,1245,1439]	8	hSpCas9	negative selection	6260952
41626603	41626626	X	-	27260156	EWS502	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.3828648778535271	[1846]	[2180,2618,2590,2867]	6	hSpCas9	negative selection	6260953
41626594	41626617	X	+	27260156	EWS502	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.3631131280091891	[371]	[421,438,696,480]	6	hSpCas9	negative selection	6260954
41609978	41610001	X	+	27260156	EWS502	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.3098010571776857	[588]	[438,648,467,452]	-5	hSpCas9	negative selection	6325230
41636606	41636629	X	+	27260156	EWS502	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.3132360513770597	[889]	[1036,1222,1247,1188]	5	hSpCas9	negative selection	6325231
41636605	41636628	X	-	27260156	EWS502	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.31712073658023454	[401]	[566,521,370,662]	5	hSpCas9	negative selection	6325232
41610011	41610034	X	-	27260156	EW8	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.4151043303185491	[822]	[1264,731,936,653]	7	hSpCas9	negative selection	6382203
41626603	41626626	X	-	27260156	EW8	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.1687990486849864	[1846]	[2240,1694,1224,1703]	3	hSpCas9	negative selection	6382204
41626594	41626617	X	+	27260156	EW8	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.44760564231168287	[371]	[573,503,245,365]	7	hSpCas9	negative selection	6382205
41609978	41610001	X	+	27260156	EW8	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.5245306435673289	[588]	[367,340,328,292]	-7	hSpCas9	negative selection	6446481
41636606	41636629	X	+	27260156	EW8	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.2514566460222295	[889]	[1006,931,757,768]	4	hSpCas9	negative selection	6446482
41636605	41636628	X	-	27260156	EW8	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.27118124168452556	[401]	[421,444,333,383]	5	hSpCas9	negative selection	6446483
41610011	41610034	X	-	27260156	CORL105	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.1978914476996052	[822]	[1140,1177,1152,955]	3	hSpCas9	negative selection	6503454
41626603	41626626	X	-	27260156	CORL105	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.30553412062023466	[1846]	[2151,2526,3744,2417]	5	hSpCas9	negative selection	6503455
41626594	41626617	X	+	27260156	CORL105	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.21336023419634131	[371]	[346,367,391,396]	-4	hSpCas9	negative selection	6503456
41609978	41610001	X	+	27260156	CORL105	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.2745612490843958	[588]	[662,416,726,503]	-5	hSpCas9	negative selection	6567732
41636606	41636629	X	+	27260156	CORL105	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.05822325766050673	[889]	[976,874,1184,1316]	1	hSpCas9	negative selection	6567733
41636605	41636628	X	-	27260156	CORL105	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.3152327006452652	[401]	[422,656,687,582]	6	hSpCas9	negative selection	6567734
41610011	41610034	X	-	27260156	HS294T	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.9551794373187625	[822]	[595,596,455,859]	9	hSpCas9	negative selection	6624705
41626603	41626626	X	-	27260156	HS294T	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.3098090975430756	[1846]	[828,879,891,953]	4	hSpCas9	negative selection	6624706
41626594	41626617	X	+	27260156	HS294T	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.2356634787682692	[371]	[116,122,109,141]	-3	hSpCas9	negative selection	6624707
41609978	41610001	X	+	27260156	HS294T	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.0683399946451308	[588]	[155,260,125,351]	-1	hSpCas9	negative selection	6688983
41636606	41636629	X	+	27260156	HS294T	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.22486506041989884	[889]	[293,478,405,442]	3	hSpCas9	negative selection	6688984
41636605	41636628	X	-	27260156	HS294T	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.8520885052159661	[401]	[217,469,216,202]	9	hSpCas9	negative selection	6688985
41610011	41610034	X	-	27260156	HCC44	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.4289912524834094	[822]	[1529,1052,1412,1092]	7	hSpCas9	negative selection	6745956
41626603	41626626	X	-	27260156	HCC44	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.2860415546132	[1846]	[2531,2447,2795,2449]	4	hSpCas9	negative selection	6745957
41626594	41626617	X	+	27260156	HCC44	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.1952573372471895	[371]	[546,285,483,634]	3	hSpCas9	negative selection	6745958
41609978	41610001	X	+	27260156	HCC44	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.06302777147429578	[588]	[546,608,864,561]	-1	hSpCas9	negative selection	6810234
41636606	41636629	X	+	27260156	HCC44	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.20506400105713285	[889]	[998,1299,1291,1032]	3	hSpCas9	negative selection	6810235
41636605	41636628	X	-	27260156	HCC44	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.05403100831542457	[401]	[424,323,821,392]	0	hSpCas9	negative selection	6810236
41610011	41610034	X	-	27260156	G402	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.638275880529954	[822]	[2127,1667,1169,1376]	7	hSpCas9	negative selection	6867207
41626603	41626626	X	-	27260156	G402	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.4029768524675943	[1846]	[2996,3254,2893,2789]	5	hSpCas9	negative selection	6867208
41626594	41626617	X	+	27260156	G402	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.49584919617407064	[371]	[209,402,257,399]	-6	hSpCas9	negative selection	6867209
41609978	41610001	X	+	27260156	G402	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.10315682707320117	[588]	[980,669,979,491]	1	hSpCas9	negative selection	6931485
41636606	41636629	X	+	27260156	G402	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.5506141045276723	[889]	[1757,1609,1450,1563]	6	hSpCas9	negative selection	6931486
41636605	41636628	X	-	27260156	G402	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.623674779855818	[401]	[628,1349,397,663]	7	hSpCas9	negative selection	6931487
41610011	41610034	X	-	27260156	L33	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.5364215517031556	[822]	[1223,526,639,1243]	9	hSpCas9	negative selection	6988458
41626603	41626626	X	-	27260156	L33	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.34398898201947437	[1846]	[2200,1010,1485,2347]	7	hSpCas9	negative selection	6988459
41626594	41626617	X	+	27260156	L33	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.06805423052342341	[371]	[320,125,217,443]	-1	hSpCas9	negative selection	6988460
41609978	41610001	X	+	27260156	L33	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.35450862770584385	[588]	[480,239,244,385]	-7	hSpCas9	negative selection	7052736
41636606	41636629	X	+	27260156	L33	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	-0.09113010875773953	[889]	[883,377,484,762]	-2	hSpCas9	negative selection	7052737
41636605	41636628	X	-	27260156	L33	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.11246116205661173	[401]	[457,165,253,469]	2	hSpCas9	negative selection	7052738
41610011	41610034	X	-	27260156	K562	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.8590718714584127	[822]	[1399,1215,1297,1373]	9	hSpCas9	negative selection	7109709
41626603	41626626	X	-	27260156	K562	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.5044373713844352	[1846]	[2560,2580,2427,1813]	6	hSpCas9	negative selection	7109710
41626594	41626617	X	+	27260156	K562	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.09879328956506106	[371]	[687,315,306,150]	1	hSpCas9	negative selection	7109711
41609978	41610001	X	+	27260156	K562	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.24844041857585036	[588]	[391,309,629,417]	-3	hSpCas9	negative selection	7173987
41636606	41636629	X	+	27260156	K562	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.3798836499442516	[889]	[1173,854,1142,946]	5	hSpCas9	negative selection	7173988
41636605	41636628	X	-	27260156	K562	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.25788053279381623	[401]	[235,399,497,539]	3	hSpCas9	negative selection	7173989
41610011	41610034	X	-	27260156	HT29	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.44227624243856245	[822]	[1461,1426,1271,1288]	8	hSpCas9	negative selection	7230960
41626603	41626626	X	-	27260156	HT29	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.2993298052052362	[1846]	[2907,2734,2658,2740]	6	hSpCas9	negative selection	7230961
41626594	41626617	X	+	27260156	HT29	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.15330084873408292	[371]	[610,477,483,447]	3	hSpCas9	negative selection	7230962
41609978	41610001	X	+	27260156	HT29	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.06746549641434402	[588]	[658,706,747,621]	-1	hSpCas9	negative selection	7295238
41636606	41636629	X	+	27260156	HT29	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.0871491452330676	[889]	[1178,1063,1122,1209]	1	hSpCas9	negative selection	7295239
41636605	41636628	X	-	27260156	HT29	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.16945016517101832	[401]	[608,581,535,482]	3	hSpCas9	negative selection	7295240
41610011	41610034	X	-	27260156	MHHES1	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.5320758273012813	[822]	[1445,1353,1383,1194]	8	hSpCas9	negative selection	7352211
41626603	41626626	X	-	27260156	MHHES1	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.49360624199730085	[1846]	[3673,2650,2994,2492]	8	hSpCas9	negative selection	7352212
41626594	41626617	X	+	27260156	MHHES1	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.1661519853037296	[371]	[418,697,387,397]	3	hSpCas9	negative selection	7352213
41609978	41610001	X	+	27260156	MHHES1	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.20831574358377675	[588]	[731,546,735,959]	4	hSpCas9	negative selection	7416489
41636606	41636629	X	+	27260156	MHHES1	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.41033535085433226	[889]	[1155,1690,1388,1125]	7	hSpCas9	negative selection	7416490
41636605	41636628	X	-	27260156	MHHES1	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.6357119105921413	[401]	[590,910,850,500]	9	hSpCas9	negative selection	7416491
41610011	41610034	X	-	27260156	MEWO	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.5001562047285404	[822]	[1344,965,1005]	8	hSpCas9	negative selection	7473462
41626603	41626626	X	-	27260156	MEWO	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.16038958976977669	[1846]	[1931,1982,1877]	3	hSpCas9	negative selection	7473463
41626594	41626617	X	+	27260156	MEWO	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.014727601760240794	[371]	[342,362,346]	0	hSpCas9	negative selection	7473464
41609978	41610001	X	+	27260156	MEWO	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.16766974511086435	[588]	[731,370,415]	-4	hSpCas9	negative selection	7537740
41636606	41636629	X	+	27260156	MEWO	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	-0.09542304552776759	[889]	[898,590,871]	-2	hSpCas9	negative selection	7537741
41636605	41636628	X	-	27260156	MEWO	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.1334130143072904	[401]	[499,300,453]	3	hSpCas9	negative selection	7537742
41610011	41610034	X	-	27260156	LNCAPCLONEFGC	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.49219515719640805	[822]	[864,1010,1318,1044]	7	hSpCas9	negative selection	7594713
41626603	41626626	X	-	27260156	LNCAPCLONEFGC	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.49840777596437635	[1846]	[2547,2337,2318,2238]	7	hSpCas9	negative selection	7594714
41626594	41626617	X	+	27260156	LNCAPCLONEFGC	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.10677518809995251	[371]	[234,349,466,417]	1	hSpCas9	negative selection	7594715
41609978	41610001	X	+	27260156	LNCAPCLONEFGC	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.26401741290886765	[588]	[806,581,660,515]	4	hSpCas9	negative selection	7658991
41636606	41636629	X	+	27260156	LNCAPCLONEFGC	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.4338845146038345	[889]	[1177,1154,1078,935]	6	hSpCas9	negative selection	7658992
41636605	41636628	X	-	27260156	LNCAPCLONEFGC	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.20664944622963538	[401]	[352,419,507,413]	3	hSpCas9	negative selection	7658993
41610011	41610034	X	-	27260156	PANC0327	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.2994407515690156	[822]	[1076,776,909,864]	4	hSpCas9	negative selection	7715964
41626603	41626626	X	-	27260156	PANC0327	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.1975492471176319	[1846]	[2838,1191,1912,1748]	3	hSpCas9	negative selection	7715965
41626594	41626617	X	+	27260156	PANC0327	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.008095379504825084	[371]	[168,413,259,446]	0	hSpCas9	negative selection	7715966
41609978	41610001	X	+	27260156	PANC0327	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.06522292460125123	[588]	[791,525,365,527]	0	hSpCas9	negative selection	7780242
41636606	41636629	X	+	27260156	PANC0327	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.39839163437200875	[889]	[906,1113,861,1263]	6	hSpCas9	negative selection	7780243
41636605	41636628	X	-	27260156	PANC0327	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	-0.136365413165758	[401]	[363,228,320,400]	-2	hSpCas9	negative selection	7780244
41610011	41610034	X	-	27260156	NCIH2009	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	1.0185454287109392	[822]	[2830,2196,2057]	9	hSpCas9	negative selection	7837215
41626603	41626626	X	-	27260156	NCIH2009	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.7063063154700926	[1846]	[4840,3764,4150]	8	hSpCas9	negative selection	7837216
41626594	41626617	X	+	27260156	NCIH2009	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.06179296415752644	[371]	[418,464,593]	-1	hSpCas9	negative selection	7837217
41609978	41610001	X	+	27260156	NCIH2009	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.00571875812140038	[588]	[989,614,889]	0	hSpCas9	negative selection	7901493
41636606	41636629	X	+	27260156	NCIH2009	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.21354192537024563	[889]	[1534,1523,1280]	3	hSpCas9	negative selection	7901494
41636605	41636628	X	-	27260156	NCIH2009	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.3309972943817085	[401]	[816,658,664]	4	hSpCas9	negative selection	7901495
41610011	41610034	X	-	27260156	NCIH1373	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.609540261070562	[822]	[1517,1385,1159,418]	6	hSpCas9	negative selection	7958466
41626603	41626626	X	-	27260156	NCIH1373	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.7304269409741011	[1846]	[3191,3700,2951,1009]	7	hSpCas9	negative selection	7958467
41626594	41626617	X	+	27260156	NCIH1373	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.13930175441935436	[371]	[368,295,773,101]	1	hSpCas9	negative selection	7958468
41609978	41610001	X	+	27260156	NCIH1373	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.37347789607542997	[588]	[512,1270,582,252]	3	hSpCas9	negative selection	8022744
41636606	41636629	X	+	27260156	NCIH1373	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.647478549525092	[889]	[2330,1141,793,576]	6	hSpCas9	negative selection	8022745
41636605	41636628	X	-	27260156	NCIH1373	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.6976365655393497	[401]	[469,727,584,294]	7	hSpCas9	negative selection	8022746
41610011	41610034	X	-	27260156	PATU8902	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	1.1362907596521337	[822]	[2324,3654,1955,2240]	9	hSpCas9	negative selection	8079717
41626603	41626626	X	-	27260156	PATU8902	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.6038133857469796	[1846]	[4357,4784,2534,4331]	6	hSpCas9	negative selection	8079718
41626594	41626617	X	+	27260156	PATU8902	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.5440901388546938	[371]	[681,941,553,909]	5	hSpCas9	negative selection	8079719
41609978	41610001	X	+	27260156	PATU8902	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.16909478895547647	[588]	[1171,640,711,1245]	1	hSpCas9	negative selection	8143995
41636606	41636629	X	+	27260156	PATU8902	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.8520106931119887	[889]	[2403,2139,2045,2408]	8	hSpCas9	negative selection	8143996
41636605	41636628	X	-	27260156	PATU8902	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.6783948088227343	[401]	[836,655,773,1401]	7	hSpCas9	negative selection	8143997
41610011	41610034	X	-	27260156	PANC1	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.5473366321958055	[822]	[957,1512,937,837]	8	hSpCas9	negative selection	8200968
41626603	41626626	X	-	27260156	PANC1	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.24505585948000985	[1846]	[1665,2525,1832,1640]	4	hSpCas9	negative selection	8200969
41626594	41626617	X	+	27260156	PANC1	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.4290115173389399	[371]	[339,466,575,353]	7	hSpCas9	negative selection	8200970
41609978	41610001	X	+	27260156	PANC1	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.07875360433334452	[588]	[357,575,643,371]	-1	hSpCas9	negative selection	8265246
41636606	41636629	X	+	27260156	PANC1	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.2898392383657832	[889]	[900,1208,734,932]	4	hSpCas9	negative selection	8265247
41636605	41636628	X	-	27260156	PANC1	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.23863189836260265	[401]	[361,609,434,279]	4	hSpCas9	negative selection	8265248
41610011	41610034	X	-	27260156	PANC0813	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.49381883206594024	[822]	[1331,1458,1203,1439]	7	hSpCas9	negative selection	8322219
41626603	41626626	X	-	27260156	PANC0813	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.3447872318522991	[1846]	[3112,2648,2710,2585]	5	hSpCas9	negative selection	8322220
41626594	41626617	X	+	27260156	PANC0813	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.09579366147323254	[371]	[449,363,419,404]	-1	hSpCas9	negative selection	8322221
41609978	41610001	X	+	27260156	PANC0813	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.43684118051896004	[588]	[613,472,456,508]	-6	hSpCas9	negative selection	8386497
41636606	41636629	X	+	27260156	PANC0813	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.014157519521774797	[889]	[1190,1088,1052,908]	0	hSpCas9	negative selection	8386498
41636605	41636628	X	-	27260156	PANC0813	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	-0.17055173478005997	[401]	[538,357,433,360]	-3	hSpCas9	negative selection	8386499
41610011	41610034	X	-	27260156	RDES	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.5998063810474803	[822]	[1170,1257,1570,1834]	8	hSpCas9	negative selection	8443470
41626603	41626626	X	-	27260156	RDES	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.45330943923595135	[1846]	[2463,2753,3128,3387]	7	hSpCas9	negative selection	8443471
41626594	41626617	X	+	27260156	RDES	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.5038602291400863	[371]	[476,583,608,797]	7	hSpCas9	negative selection	8443472
41609978	41610001	X	+	27260156	RDES	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.11962050017100742	[588]	[647,545,675,602]	-2	hSpCas9	negative selection	8507748
41636606	41636629	X	+	27260156	RDES	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.3884402998326696	[889]	[1245,1217,1514,1380]	6	hSpCas9	negative selection	8507749
41636605	41636628	X	-	27260156	RDES	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.144061262052104	[401]	[275,503,606,732]	2	hSpCas9	negative selection	8507750
41610011	41610034	X	-	27260156	PC3	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.5019730795187971	[822]	[563,1208,2014,1368]	8	hSpCas9	negative selection	8564721
41626603	41626626	X	-	27260156	PC3	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.2950342747585475	[1846]	[1523,2034,4099,2191]	6	hSpCas9	negative selection	8564722
41626594	41626617	X	+	27260156	PC3	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.1265545474488018	[371]	[204,324,766,528]	3	hSpCas9	negative selection	8564723
41609978	41610001	X	+	27260156	PC3	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.017916261191403493	[588]	[317,633,1267,483]	0	hSpCas9	negative selection	8628999
41636606	41636629	X	+	27260156	PC3	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	-0.0756477370841604	[889]	[466,601,1585,1120]	-2	hSpCas9	negative selection	8629000
41636605	41636628	X	-	27260156	PC3	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	-0.09971852573582557	[401]	[210,428,482,452]	-2	hSpCas9	negative selection	8629001
41610011	41610034	X	-	27260156	PATU8988T	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.36600176103068516	[822]	[854,1320,1059,878]	6	hSpCas9	negative selection	8685972
41626603	41626626	X	-	27260156	PATU8988T	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.4102732959578914	[1846]	[2460,2562,1959,2539]	7	hSpCas9	negative selection	8685973
41626594	41626617	X	+	27260156	PATU8988T	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.10855571512507695	[371]	[284,326,261,470]	-2	hSpCas9	negative selection	8685974
41609978	41610001	X	+	27260156	PATU8988T	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.3040532868028508	[588]	[337,471,536,499]	-5	hSpCas9	negative selection	8750250
41636606	41636629	X	+	27260156	PATU8988T	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.46736198914504523	[889]	[1158,1541,901,1189]	7	hSpCas9	negative selection	8750251
41636605	41636628	X	-	27260156	PATU8988T	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.5434987069574753	[401]	[667,620,355,632]	8	hSpCas9	negative selection	8750252
41610011	41610034	X	-	27260156	T47D	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.43445474566795084	[822]	[1247,1323,1360,1243]	8	hSpCas9	negative selection	8807223
41626603	41626626	X	-	27260156	T47D	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.29274110988723856	[1846]	[2563,2537,2763,2683]	6	hSpCas9	negative selection	8807224
41626594	41626617	X	+	27260156	T47D	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.22481009494753146	[371]	[505,446,606,467]	5	hSpCas9	negative selection	8807225
41609978	41610001	X	+	27260156	T47D	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.11823424135295965	[588]	[570,590,577,797]	-3	hSpCas9	negative selection	8871501
41636606	41636629	X	+	27260156	T47D	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.22528220039589641	[889]	[1241,1111,1278,1222]	5	hSpCas9	negative selection	8871502
41636605	41636628	X	-	27260156	T47D	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.18281697760759952	[401]	[544,510,578,490]	4	hSpCas9	negative selection	8871503
41610011	41610034	X	-	27260156	SU8686	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.68003020545256	[822]	[1080,1227,1549,1421]	9	hSpCas9	negative selection	8928474
41626603	41626626	X	-	27260156	SU8686	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.38449299009673576	[1846]	[2077,2209,2574,2813]	6	hSpCas9	negative selection	8928475
41626594	41626617	X	+	27260156	SU8686	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	-0.07079602773267019	[371]	[322,308,372,416]	-1	hSpCas9	negative selection	8928476
41609978	41610001	X	+	27260156	SU8686	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	0.0033240614352288422	[588]	[643,467,650,583]	0	hSpCas9	negative selection	8992752
41636606	41636629	X	+	27260156	SU8686	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.18354746121296783	[889]	[816,981,1179,1059]	3	hSpCas9	negative selection	8992753
41636605	41636628	X	-	27260156	SU8686	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.3564942444371024	[401]	[412,544,438,670]	6	hSpCas9	negative selection	8992754
41610011	41610034	X	-	27260156	SKES1	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.5093848716751856	[822]	[1256,1300,946,1185]	8	hSpCas9	negative selection	9049725
41626603	41626626	X	-	27260156	SKES1	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.48371722201522105	[1846]	[2703,2929,2339,2389]	8	hSpCas9	negative selection	9049726
41626594	41626617	X	+	27260156	SKES1	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.3085098488097242	[371]	[523,494,402,428]	6	hSpCas9	negative selection	9049727
41609978	41610001	X	+	27260156	SKES1	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.10893025672979942	[588]	[419,578,653,509]	-2	hSpCas9	negative selection	9114003
41636606	41636629	X	+	27260156	SKES1	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.31656023824061374	[889]	[1458,1183,1075,788]	6	hSpCas9	negative selection	9114004
41636605	41636628	X	-	27260156	SKES1	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	-0.033042121366137545	[401]	[488,532,340,248]	0	hSpCas9	negative selection	9114005
41610011	41610034	X	-	27260156	TOV112D	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.37452416693725854	[822]	[1066,1435,721,1135]	7	hSpCas9	negative selection	9170976
41626603	41626626	X	-	27260156	TOV112D	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.23910888207508507	[1846]	[2288,2587,2097,1871]	4	hSpCas9	negative selection	9170977
41626594	41626617	X	+	27260156	TOV112D	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.38098011158946204	[371]	[428,517,537,458]	7	hSpCas9	negative selection	9170978
41609978	41610001	X	+	27260156	TOV112D	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.21336107777312358	[588]	[475,450,529,558]	-4	hSpCas9	negative selection	9235254
41636606	41636629	X	+	27260156	TOV112D	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.12718711816079697	[889]	[1416,1032,756,743]	2	hSpCas9	negative selection	9235255
41636605	41636628	X	-	27260156	TOV112D	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	-0.13075681435692632	[401]	[329,612,342,244]	-3	hSpCas9	negative selection	9235256
41610011	41610034	X	-	27260156	TC71	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.37408139378827676	[822]	[1103,1080,1052,1351]	8	hSpCas9	negative selection	9292227
41626603	41626626	X	-	27260156	TC71	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.2660086805450341	[1846]	[2429,2209,2296,2600]	6	hSpCas9	negative selection	9292228
41626594	41626617	X	+	27260156	TC71	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.17103956667951223	[371]	[546,374,367,509]	4	hSpCas9	negative selection	9292229
41609978	41610001	X	+	27260156	TC71	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.3283106542500915	[588]	[431,458,548,575]	-7	hSpCas9	negative selection	9356505
41636606	41636629	X	+	27260156	TC71	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.2884197953781996	[889]	[1282,1156,1030,1192]	7	hSpCas9	negative selection	9356506
41636605	41636628	X	-	27260156	TC71	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.1062972280212629	[401]	[507,420,436,490]	2	hSpCas9	negative selection	9356507
41610011	41610034	X	-	27260156	TC32	viability	CCCCTTAGGAGCAGTCTCACAGG	CASK	ENSG00000147044	0.6083408700438353	[822]	[970,1143,1435,1173]	8	hSpCas9	negative selection	9413478
41626603	41626626	X	-	27260156	TC32	viability	TCCGAAGACCCTACCTCCTCAGG	CASK	ENSG00000147044	0.37088074734666576	[1846]	[1990,1777,2981,2439]	6	hSpCas9	negative selection	9413479
41626594	41626617	X	+	27260156	TC32	viability	ATCCAATTACCTGAGGAGGTAGG	CASK	ENSG00000147044	0.10519462427309939	[371]	[458,222,442,417]	2	hSpCas9	negative selection	9413480
41609978	41610001	X	+	27260156	TC32	viability	TAAGCGCATGAATCTCTTCCAGG	CASK	ENSG00000147044	-0.26472215036885166	[588]	[432,242,739,540]	-5	hSpCas9	negative selection	9477756
41636606	41636629	X	+	27260156	TC32	viability	CTCAGCTGCTCTACTGTTTCTGG	CASK	ENSG00000147044	0.5436350195005416	[889]	[1249,970,1600,1129]	8	hSpCas9	negative selection	9477757
41636605	41636628	X	-	27260156	TC32	viability	CAGAAACAGTAGAGCAGCTGAGG	CASK	ENSG00000147044	0.10128447124359367	[401]	[377,275,589,439]	1	hSpCas9	negative selection	9477758
41578430	41578453	X	+	27869803	HPAFII	viability after 27 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	0.41289233034546297	[162]	[16,194,NaN]	3	hSpCas9	negative selection	9608743
41609996	41610019	X	-	27869803	HPAFII	viability after 27 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	1.0014918125880046	[293]	[315,303,NaN]	8	hSpCas9	negative selection	9608744
41660428	41660451	X	+	27869803	HPAFII	viability after 27 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	1.063169124045809	[404]	[439,448,NaN]	8	hSpCas9	negative selection	9608745
41745523	41745546	X	-	27869803	HPAFII	viability after 27 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.6370047781907928	[149]	[114,128,NaN]	5	hSpCas9	negative selection	9608750
41853114	41853137	X	-	27869803	HPAFII	viability after 27 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.10120562466060734	[117]	[35,91,NaN]	0	hSpCas9	negative selection	9608751
41922968	41922991	X	+	27869803	HPAFII	viability after 27 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.8458736839571546	[387]	[526,232,NaN]	7	hSpCas9	negative selection	9608752
41578430	41578453	X	+	27869803	HPAFII	viability after 15 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	0.2539003536122754	[162]	[108,270,NaN]	3	hSpCas9	negative selection	9691192
41609996	41610019	X	-	27869803	HPAFII	viability after 15 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.9368202576707033	[293]	[750,513,NaN]	8	hSpCas9	negative selection	9691193
41660428	41660451	X	+	27869803	HPAFII	viability after 15 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.94209145387811	[404]	[810,851,NaN]	9	hSpCas9	negative selection	9691194
41745523	41745546	X	-	27869803	HPAFII	viability after 15 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	-0.6613175467438281	[149]	[96,104,NaN]	-6	hSpCas9	negative selection	9691199
41853114	41853137	X	-	27869803	HPAFII	viability after 15 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.6388720915935924	[117]	[231,175,NaN]	7	hSpCas9	negative selection	9691200
41922968	41922991	X	+	27869803	HPAFII	viability after 15 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	0.5706371435331847	[387]	[926,427,NaN]	6	hSpCas9	negative selection	9691201
41578430	41578453	X	+	27869803	ASPC1	viability after 36 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.16038113620608463	[357]	[160,111,75]	-2	hSpCas9	negative selection	9773641
41609996	41610019	X	-	27869803	ASPC1	viability after 36 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	-0.31895487466085554	[1098]	[148,476,280]	-3	hSpCas9	negative selection	9773642
41660428	41660451	X	+	27869803	ASPC1	viability after 36 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	-0.49966816246495604	[1253]	[422,428,131]	-5	hSpCas9	negative selection	9773643
41745523	41745546	X	-	27869803	ASPC1	viability after 36 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.1780878913497017	[387]	[162,191,113]	1	hSpCas9	negative selection	9773648
41853114	41853137	X	-	27869803	ASPC1	viability after 36 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	-1.008647764310839	[506]	[148,57,67]	-7	hSpCas9	negative selection	9773649
41922968	41922991	X	+	27869803	ASPC1	viability after 36 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-1.0379232214919965	[1043]	[352,65,140]	-7	hSpCas9	negative selection	9773650
41578430	41578453	X	+	27869803	PATU8988S	viability after 35 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.04426022038583255	[274]	[67,146,NaN]	0	hSpCas9	negative selection	9856090
41609996	41610019	X	-	27869803	PATU8988S	viability after 35 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	-0.3728133289140498	[933]	[292,287,NaN]	-4	hSpCas9	negative selection	9856091
41660428	41660451	X	+	27869803	PATU8988S	viability after 35 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	-1.0245778880078737	[992]	[234,157,NaN]	-7	hSpCas9	negative selection	9856092
41745523	41745546	X	-	27869803	PATU8988S	viability after 35 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	-0.2501066974948267	[331]	[81,142,NaN]	-3	hSpCas9	negative selection	9856097
41853114	41853137	X	-	27869803	PATU8988S	viability after 35 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	-0.7711752602527167	[395]	[71,114,NaN]	-6	hSpCas9	negative selection	9856098
41922968	41922991	X	+	27869803	PATU8988S	viability after 35 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.5797196462583118	[1010]	[246,297,NaN]	-5	hSpCas9	negative selection	9856099
41578430	41578453	X	+	27869803	PATU8988S	viability after 31 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.3927833443873082	[274]	[79,87,NaN]	-4	hSpCas9	negative selection	9938539
41609996	41610019	X	-	27869803	PATU8988S	viability after 31 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.09068312586367588	[933]	[334,474,NaN]	1	hSpCas9	negative selection	9938540
41660428	41660451	X	+	27869803	PATU8988S	viability after 31 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	-0.5669927533341963	[992]	[250,287,NaN]	-6	hSpCas9	negative selection	9938541
41745523	41745546	X	-	27869803	PATU8988S	viability after 31 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	-0.7324626281670172	[331]	[69,91,NaN]	-7	hSpCas9	negative selection	9938546
41853114	41853137	X	-	27869803	PATU8988S	viability after 31 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	-0.9689075848356183	[395]	[37,134,NaN]	-7	hSpCas9	negative selection	9938547
41922968	41922991	X	+	27869803	PATU8988S	viability after 31 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	-0.47008985004437015	[1010]	[228,369,NaN]	-5	hSpCas9	negative selection	9938548
41578430	41578453	X	+	27869803	HPAFII	viability after 35 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.47609293821485366	[162]	[0,124,NaN]	-3	hSpCas9	negative selection	10020988
41609996	41610019	X	-	27869803	HPAFII	viability after 35 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.9455537250569114	[293]	[288,283,NaN]	6	hSpCas9	negative selection	10020989
41660428	41660451	X	+	27869803	HPAFII	viability after 35 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.6261649353110734	[404]	[164,486,NaN]	4	hSpCas9	negative selection	10020990
41745523	41745546	X	-	27869803	HPAFII	viability after 35 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	0.8769619011854903	[149]	[114,166,NaN]	6	hSpCas9	negative selection	10020995
41853114	41853137	X	-	27869803	HPAFII	viability after 35 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.5672121281138016	[117]	[48,132,NaN]	3	hSpCas9	negative selection	10020996
41922968	41922991	X	+	27869803	HPAFII	viability after 35 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	1.7434346931681808	[387]	[620,698,NaN]	9	hSpCas9	negative selection	10020997
41578430	41578453	X	+	27869803	HPAFII	viability after 31 days	ATCGCCGTTTAAATAGGGAGAGG	CASK	ENSG00000147044	-0.24937362166169086	[162]	[8,150,NaN]	-2	hSpCas9	negative selection	10103437
41609996	41610019	X	-	27869803	HPAFII	viability after 31 days	CTCACAGGTGCTGGACAGCCTGG	CASK	ENSG00000147044	0.7661435011998482	[293]	[271,289,NaN]	5	hSpCas9	negative selection	10103438
41660428	41660451	X	+	27869803	HPAFII	viability after 31 days	TGCTCATGTACCTTAAGCCATGG	CASK	ENSG00000147044	0.6023443172777434	[404]	[167,537,NaN]	4	hSpCas9	negative selection	10103439
41745523	41745546	X	-	27869803	HPAFII	viability after 31 days	TGTACAGTGAAGCTGTAGCCAGG	CASK	ENSG00000147044	-0.36769943338723565	[149]	[25,107,NaN]	-2	hSpCas9	negative selection	10103444
41853114	41853137	X	-	27869803	HPAFII	viability after 31 days	AGTCCAGGGTTAAGTACAGAAGG	CASK	ENSG00000147044	0.38225560209639087	[117]	[70,102,NaN]	2	hSpCas9	negative selection	10103445
41922968	41922991	X	+	27869803	HPAFII	viability after 31 days	CAGCACGTCGTCGTCGGCCATGG	CASK	ENSG00000147044	1.249152164593275	[387]	[530,502,NaN]	8	hSpCas9	negative selection	10103446
41660445	41660468	X	-	28162770	P31FUJ	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.5532289488341786	[184]	[318]	6	hSpCas9	negative selection	10126116
41853129	41853152	X	-	28162770	P31FUJ	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.39162744764401425	[636]	[981]	4	hSpCas9	negative selection	10126117
41561579	41561602	X	-	28162770	P31FUJ	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.3406340429257503	[376]	[560]	4	hSpCas9	negative selection	10126118
41671508	41671531	X	+	28162770	P31FUJ	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-0.8672848409793336	[162]	[104]	-6	hSpCas9	negative selection	10126119
41636587	41636610	X	-	28162770	P31FUJ	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.3537057651646808	[310]	[466]	4	hSpCas9	negative selection	10126120
41626668	41626691	X	+	28162770	P31FUJ	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.5943611987234056	[309]	[549]	6	hSpCas9	negative selection	10126121
41626626	41626649	X	+	28162770	P31FUJ	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.33382847353452005	[527]	[781]	3	hSpCas9	negative selection	10126122
41578433	41578456	X	+	28162770	P31FUJ	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.45987411360703073	[171]	[277]	5	hSpCas9	negative selection	10126123
41553843	41553866	X	+	28162770	P31FUJ	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.7441358887223963	[535]	[1054]	8	hSpCas9	negative selection	10126124
41542784	41542807	X	-	28162770	P31FUJ	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.4401910606604982	[497]	[793]	5	hSpCas9	negative selection	10126125
41660445	41660468	X	-	28162770	TF1	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10295482
41853129	41853152	X	-	28162770	TF1	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	NaN	[NaN]	[871]	1	hSpCas9	negative selection	10295483
41561579	41561602	X	-	28162770	TF1	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	NaN	[NaN]	[406]	1	hSpCas9	negative selection	10295484
41671508	41671531	X	+	28162770	TF1	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	NaN	[NaN]	[221]	1	hSpCas9	negative selection	10295485
41636587	41636610	X	-	28162770	TF1	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	NaN	[NaN]	[342]	1	hSpCas9	negative selection	10295486
41626668	41626691	X	+	28162770	TF1	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	NaN	[NaN]	[533]	1	hSpCas9	negative selection	10295487
41626626	41626649	X	+	28162770	TF1	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	NaN	[NaN]	[472]	1	hSpCas9	negative selection	10295488
41578433	41578456	X	+	28162770	TF1	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	NaN	[NaN]	[257]	1	hSpCas9	negative selection	10295489
41553843	41553866	X	+	28162770	TF1	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	NaN	[NaN]	[661]	1	hSpCas9	negative selection	10295490
41542784	41542807	X	-	28162770	TF1	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	NaN	[NaN]	[767]	1	hSpCas9	negative selection	10295491
41660445	41660468	X	-	28162770	SKM1	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.07490480901389068	[57]	[107]	0	hSpCas9	negative selection	10464848
41853129	41853152	X	-	28162770	SKM1	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.027131636351366728	[140]	[253]	0	hSpCas9	negative selection	10464849
41561579	41561602	X	-	28162770	SKM1	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.5219527031953555	[116]	[296]	5	hSpCas9	negative selection	10464850
41671508	41671531	X	+	28162770	SKM1	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-0.728892293630524	[44]	[47]	-5	hSpCas9	negative selection	10464851
41636587	41636610	X	-	28162770	SKM1	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.43175489422377755	[64]	[154]	4	hSpCas9	negative selection	10464852
41626668	41626691	X	+	28162770	SKM1	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.768607365840293	[84]	[255]	7	hSpCas9	negative selection	10464853
41626626	41626649	X	+	28162770	SKM1	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.6068416007818689	[90]	[244]	6	hSpCas9	negative selection	10464854
41578433	41578456	X	+	28162770	SKM1	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	-0.9569312781081141	[55]	[50]	-6	hSpCas9	negative selection	10464855
41553843	41553866	X	+	28162770	SKM1	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	1.1779983019779943	[110]	[443]	9	hSpCas9	negative selection	10464856
41542784	41542807	X	-	28162770	SKM1	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.4299775193027924	[130]	[311]	4	hSpCas9	negative selection	10464857
41660445	41660468	X	-	28162770	SKM1	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.07490480901389068	[57]	[107]	0	hSpCas9	negative selection	10634214
41853129	41853152	X	-	28162770	SKM1	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.027131636351366728	[140]	[253]	0	hSpCas9	negative selection	10634215
41561579	41561602	X	-	28162770	SKM1	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.5219527031953555	[116]	[296]	5	hSpCas9	negative selection	10634216
41671508	41671531	X	+	28162770	SKM1	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-0.728892293630524	[44]	[47]	-5	hSpCas9	negative selection	10634217
41636587	41636610	X	-	28162770	SKM1	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.43175489422377755	[64]	[154]	4	hSpCas9	negative selection	10634218
41626668	41626691	X	+	28162770	SKM1	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.768607365840293	[84]	[255]	7	hSpCas9	negative selection	10634219
41626626	41626649	X	+	28162770	SKM1	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.6068416007818689	[90]	[244]	6	hSpCas9	negative selection	10634220
41578433	41578456	X	+	28162770	SKM1	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	-0.9569312781081141	[55]	[50]	-6	hSpCas9	negative selection	10634221
41553843	41553866	X	+	28162770	SKM1	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	1.1779983019779943	[110]	[443]	9	hSpCas9	negative selection	10634222
41542784	41542807	X	-	28162770	SKM1	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.4299775193027924	[130]	[311]	4	hSpCas9	negative selection	10634223
41660445	41660468	X	-	28162770	PL21	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	1.2799929221785349	[245]	[259]	9	hSpCas9	negative selection	10803580
41853129	41853152	X	-	28162770	PL21	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	1.3564428453679958	[401]	[447]	9	hSpCas9	negative selection	10803581
41561579	41561602	X	-	28162770	PL21	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	-0.26019623171809103	[398]	[144]	-2	hSpCas9	negative selection	10803582
41671508	41671531	X	+	28162770	PL21	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	0.10757349575324746	[176]	[82]	0	hSpCas9	negative selection	10803583
41636587	41636610	X	-	28162770	PL21	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	-0.036466666066828635	[237]	[100]	0	hSpCas9	negative selection	10803584
41626668	41626691	X	+	28162770	PL21	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.5027023845097516	[299]	[184]	4	hSpCas9	negative selection	10803585
41626626	41626649	X	+	28162770	PL21	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	-0.536825979676886	[359]	[107]	-4	hSpCas9	negative selection	10803586
41578433	41578456	X	+	28162770	PL21	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.18128058723800436	[153]	[75]	1	hSpCas9	negative selection	10803587
41553843	41553866	X	+	28162770	PL21	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.7614508471458309	[327]	[241]	6	hSpCas9	negative selection	10803588
41542784	41542807	X	-	28162770	PL21	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.965933861714745	[326]	[277]	7	hSpCas9	negative selection	10803589
41660445	41660468	X	-	28162770	P31FUJ	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.5532289488341786	[184]	[318]	6	hSpCas9	negative selection	10972946
41853129	41853152	X	-	28162770	P31FUJ	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.39162744764401425	[636]	[981]	4	hSpCas9	negative selection	10972947
41561579	41561602	X	-	28162770	P31FUJ	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.3406340429257503	[376]	[560]	4	hSpCas9	negative selection	10972948
41671508	41671531	X	+	28162770	P31FUJ	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-0.8672848409793336	[162]	[104]	-6	hSpCas9	negative selection	10972949
41636587	41636610	X	-	28162770	P31FUJ	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.3537057651646808	[310]	[466]	4	hSpCas9	negative selection	10972950
41626668	41626691	X	+	28162770	P31FUJ	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.5943611987234056	[309]	[549]	6	hSpCas9	negative selection	10972951
41626626	41626649	X	+	28162770	P31FUJ	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.33382847353452005	[527]	[781]	3	hSpCas9	negative selection	10972952
41578433	41578456	X	+	28162770	P31FUJ	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.45987411360703073	[171]	[277]	5	hSpCas9	negative selection	10972953
41553843	41553866	X	+	28162770	P31FUJ	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.7441358887223963	[535]	[1054]	8	hSpCas9	negative selection	10972954
41542784	41542807	X	-	28162770	P31FUJ	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.4401910606604982	[497]	[793]	5	hSpCas9	negative selection	10972955
41660445	41660468	X	-	28162770	OCIAML5	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.03427664734043581	[98]	[182]	0	hSpCas9	negative selection	11142312
41853129	41853152	X	-	28162770	OCIAML5	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.1643411856576158	[305]	[618]	1	hSpCas9	negative selection	11142313
41561579	41561602	X	-	28162770	OCIAML5	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.9593238644287638	[152]	[536]	8	hSpCas9	negative selection	11142314
41671508	41671531	X	+	28162770	OCIAML5	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	1.2174185294572872	[75]	[318]	9	hSpCas9	negative selection	11142315
41636587	41636610	X	-	28162770	OCIAML5	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.9720154375990557	[97]	[346]	8	hSpCas9	negative selection	11142316
41626668	41626691	X	+	28162770	OCIAML5	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.9129309589443128	[157]	[536]	7	hSpCas9	negative selection	11142317
41626626	41626649	X	+	28162770	OCIAML5	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.4404320471607248	[415]	[1018]	4	hSpCas9	negative selection	11142318
41578433	41578456	X	+	28162770	OCIAML5	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	1.7821394488770081	[71]	[446]	9	hSpCas9	negative selection	11142319
41553843	41553866	X	+	28162770	OCIAML5	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.2524893601785927	[305]	[657]	2	hSpCas9	negative selection	11142320
41542784	41542807	X	-	28162770	OCIAML5	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.9383650481571388	[195]	[677]	7	hSpCas9	negative selection	11142321
41660445	41660468	X	-	28162770	EOL1	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.882422295897858	[416]	[404]	7	hSpCas9	negative selection	11311678
41853129	41853152	X	-	28162770	EOL1	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.6615133657367407	[581]	[484]	6	hSpCas9	negative selection	11311679
41561579	41561602	X	-	28162770	EOL1	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.8491403689125121	[647]	[614]	7	hSpCas9	negative selection	11311680
41671508	41671531	X	+	28162770	EOL1	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-1.2153824895739405	[356]	[80]	-7	hSpCas9	negative selection	11311681
41636587	41636610	X	-	28162770	EOL1	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.5839810933227105	[408]	[322]	5	hSpCas9	negative selection	11311682
41626668	41626691	X	+	28162770	EOL1	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.7602583047976548	[510]	[455]	6	hSpCas9	negative selection	11311683
41626626	41626649	X	+	28162770	EOL1	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.5496707967342133	[554]	[427]	5	hSpCas9	negative selection	11311684
41578433	41578456	X	+	28162770	EOL1	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.8176325676540226	[139]	[129]	7	hSpCas9	negative selection	11311685
41553843	41553866	X	+	28162770	EOL1	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.6525179888242131	[546]	[452]	6	hSpCas9	negative selection	11311686
41542784	41542807	X	-	28162770	EOL1	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.8658384642720753	[651]	[625]	7	hSpCas9	negative selection	11311687
41660445	41660468	X	-	28162770	MOLM13	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	1.5991339148228314	[314]	[689]	9	hSpCas9	negative selection	11481044
41853129	41853152	X	-	28162770	MOLM13	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.014618747533955645	[700]	[511]	0	hSpCas9	negative selection	11481045
41561579	41561602	X	-	28162770	MOLM13	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	1.4649055231057577	[483]	[965]	9	hSpCas9	negative selection	11481046
41671508	41671531	X	+	28162770	MOLM13	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	0.33552916107060354	[307]	[280]	2	hSpCas9	negative selection	11481047
41636587	41636610	X	-	28162770	MOLM13	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	1.1015257290014246	[407]	[632]	8	hSpCas9	negative selection	11481048
41626668	41626691	X	+	28162770	MOLM13	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	1.4114400511263931	[429]	[826]	9	hSpCas9	negative selection	11481049
41626626	41626649	X	+	28162770	MOLM13	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	-0.08481275545397926	[596]	[406]	0	hSpCas9	negative selection	11481050
41578433	41578456	X	+	28162770	MOLM13	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.8807525095890857	[165]	[220]	6	hSpCas9	negative selection	11481051
41553843	41553866	X	+	28162770	MOLM13	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.1779041791599707	[669]	[547]	1	hSpCas9	negative selection	11481052
41542784	41542807	X	-	28162770	MOLM13	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	-0.6462816383747322	[735]	[339]	-4	hSpCas9	negative selection	11481053
41660445	41660468	X	-	28162770	HEL	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.42903213853013134	[275]	[237]	3	hSpCas9	negative selection	11650410
41853129	41853152	X	-	28162770	HEL	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	1.3497888482622755	[535]	[874]	9	hSpCas9	negative selection	11650411
41561579	41561602	X	-	28162770	HEL	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.7566200215552292	[486]	[526]	6	hSpCas9	negative selection	11650412
41671508	41671531	X	+	28162770	HEL	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	0.8589194244035421	[265]	[308]	7	hSpCas9	negative selection	11650413
41636587	41636610	X	-	28162770	HEL	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.9817220910674493	[369]	[467]	8	hSpCas9	negative selection	11650414
41626668	41626691	X	+	28162770	HEL	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	1.5722512245325806	[366]	[698]	9	hSpCas9	negative selection	11650415
41626626	41626649	X	+	28162770	HEL	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	-0.09834287063808123	[467]	[279]	0	hSpCas9	negative selection	11650416
41578433	41578456	X	+	28162770	HEL	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.35894586599976575	[167]	[137]	3	hSpCas9	negative selection	11650417
41553843	41553866	X	+	28162770	HEL	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	-0.18060582093810995	[498]	[281]	-1	hSpCas9	negative selection	11650418
41542784	41542807	X	-	28162770	HEL	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.10744371609389058	[570]	[393]	0	hSpCas9	negative selection	11650419
41660445	41660468	X	-	28162770	MV411	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	1.2368424355435765	[204]	[406]	9	hSpCas9	negative selection	11819776
41853129	41853152	X	-	28162770	MV411	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.08759370412054213	[409]	[366]	0	hSpCas9	negative selection	11819777
41561579	41561602	X	-	28162770	MV411	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.5858210613311954	[400]	[506]	5	hSpCas9	negative selection	11819778
41671508	41671531	X	+	28162770	MV411	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-0.06450645553196503	[179]	[144]	0	hSpCas9	negative selection	11819779
41636587	41636610	X	-	28162770	MV411	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.9146148147921189	[215]	[342]	7	hSpCas9	negative selection	11819780
41626668	41626691	X	+	28162770	MV411	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.9671595726470847	[302]	[498]	8	hSpCas9	negative selection	11819781
41626626	41626649	X	+	28162770	MV411	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.8110507313104982	[294]	[435]	7	hSpCas9	negative selection	11819782
41578433	41578456	X	+	28162770	MV411	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	-0.13259349866815529	[94]	[72]	-1	hSpCas9	negative selection	11819783
41553843	41553866	X	+	28162770	MV411	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.5975575733802807	[374]	[477]	5	hSpCas9	negative selection	11819784
41542784	41542807	X	-	28162770	MV411	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	1.2774947846389555	[379]	[775]	9	hSpCas9	negative selection	11819785
41660445	41660468	X	-	28162770	MONOMAC1	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.8253309659689009	[159]	[324]	7	hSpCas9	negative selection	11989142
41853129	41853152	X	-	28162770	MONOMAC1	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.29152116970854003	[262]	[368]	3	hSpCas9	negative selection	11989143
41561579	41561602	X	-	28162770	MONOMAC1	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.344233063634205	[256]	[373]	3	hSpCas9	negative selection	11989144
41671508	41671531	X	+	28162770	MONOMAC1	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	0.5603928496663682	[125]	[212]	5	hSpCas9	negative selection	11989145
41636587	41636610	X	-	28162770	MONOMAC1	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.9358574234377917	[170]	[374]	8	hSpCas9	negative selection	11989146
41626668	41626691	X	+	28162770	MONOMAC1	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.43597778306774426	[186]	[289]	4	hSpCas9	negative selection	11989147
41626626	41626649	X	+	28162770	MONOMAC1	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.8453984192608431	[200]	[413]	7	hSpCas9	negative selection	11989148
41578433	41578456	X	+	28162770	MONOMAC1	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.19398377110075452	[105]	[138]	2	hSpCas9	negative selection	11989149
41553843	41553866	X	+	28162770	MONOMAC1	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	1.3171043164719056	[166]	[476]	9	hSpCas9	negative selection	11989150
41542784	41542807	X	-	28162770	MONOMAC1	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.6509600594953964	[279]	[503]	6	hSpCas9	negative selection	11989151
41660445	41660468	X	-	28162770	OCIAML2	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	1.041015997836074	[36]	[421]	8	hSpCas9	negative selection	12158508
41853129	41853152	X	-	28162770	OCIAML2	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.6652536028396117	[80]	[711]	6	hSpCas9	negative selection	12158509
41561579	41561602	X	-	28162770	OCIAML2	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.3820740839903165	[84]	[613]	3	hSpCas9	negative selection	12158510
41671508	41671531	X	+	28162770	OCIAML2	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	0.21669439310867278	[33]	[218]	2	hSpCas9	negative selection	12158511
41636587	41636610	X	-	28162770	OCIAML2	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	1.1143326754789948	[34]	[419]	9	hSpCas9	negative selection	12158512
41626668	41626691	X	+	28162770	OCIAML2	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.9986664133046919	[52]	[586]	8	hSpCas9	negative selection	12158513
41626626	41626649	X	+	28162770	OCIAML2	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	0.47552020081358415	[57]	[446]	4	hSpCas9	negative selection	12158514
41578433	41578456	X	+	28162770	OCIAML2	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	1.1213874330129454	[16]	[204]	9	hSpCas9	negative selection	12158515
41553843	41553866	X	+	28162770	OCIAML2	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.4625048696168844	[68]	[526]	4	hSpCas9	negative selection	12158516
41542784	41542807	X	-	28162770	OCIAML2	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.24857692229446626	[93]	[618]	2	hSpCas9	negative selection	12158517
41660445	41660468	X	-	28162770	OCIAML3	viability	ATGAAGCACTGAATCACCCATGG	CASK	ENSG00000147044	0.25398926623078677	[64]	[233]	2	hSpCas9	negative selection	12327874
41853129	41853152	X	-	28162770	OCIAML3	viability	GCCAAGTTCACATCAAGTCCAGG	CASK	ENSG00000147044	0.767968615203267	[134]	[693]	7	hSpCas9	negative selection	12327875
41561579	41561602	X	-	28162770	OCIAML3	viability	CAGTGTGGCTAACCAAACAGTGG	CASK	ENSG00000147044	0.2782368124774641	[117]	[431]	2	hSpCas9	negative selection	12327876
41671508	41671531	X	+	28162770	OCIAML3	viability	GAGGCAAGGAGAACACAGTGGGG	CASK	ENSG00000147044	-1.1324275551082892	[60]	[83]	-7	hSpCas9	negative selection	12327877
41636587	41636610	X	-	28162770	OCIAML3	viability	TGAGGAAATTCAATGCAAGGAGG	CASK	ENSG00000147044	0.3115276756723445	[70]	[265]	3	hSpCas9	negative selection	12327878
41626668	41626691	X	+	28162770	OCIAML3	viability	GAATTTGTGACTTGACACAGCGG	CASK	ENSG00000147044	0.4019792971692133	[89]	[358]	4	hSpCas9	negative selection	12327879
41626626	41626649	X	+	28162770	OCIAML3	viability	GAAATCTGGTAACTCTTCAGGGG	CASK	ENSG00000147044	-0.40534607630026487	[135]	[309]	-3	hSpCas9	negative selection	12327880
41578433	41578456	X	+	28162770	OCIAML3	viability	GCCGTTTAAATAGGGAGAGGTGG	CASK	ENSG00000147044	0.5249334323993443	[31]	[138]	5	hSpCas9	negative selection	12327881
41553843	41553866	X	+	28162770	OCIAML3	viability	GAATGCCAGCTTCTTTACAGGGG	CASK	ENSG00000147044	0.42132401343182746	[116]	[472]	4	hSpCas9	negative selection	12327882
41542784	41542807	X	-	28162770	OCIAML3	viability	GCGAGTAGCTTGCATTGCCATGG	CASK	ENSG00000147044	0.6309587246761112	[119]	[560]	6	hSpCas9	negative selection	12327883