Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:836
• Symbol:CASP3
• Description:caspase 3

DataSource: http://genomecrispr.dkfz.de/#!/results/CASP3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
184631073	184631096	4	-	26472758	Jiyoye	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.03520660411891541	[87]	[67]	0	hSpCas9	negative selection	23749
184631129	184631152	4	-	26472758	Jiyoye	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	-0.04430411374103049	[293]	[214]	0	hSpCas9	negative selection	23750
184631883	184631906	4	-	26472758	Jiyoye	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.5382743717786167	[430]	[471]	4	hSpCas9	negative selection	23751
184631147	184631170	4	-	26472758	Jiyoye	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.9005074067614612	[129]	[182]	6	hSpCas9	negative selection	23752
184631026	184631049	4	+	26472758	Jiyoye	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.7509337244174511	[222]	[282]	5	hSpCas9	negative selection	23753
184631111	184631134	4	-	26472758	Jiyoye	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.9486362435904431	[201]	[293]	6	hSpCas9	negative selection	23754
184631047	184631070	4	+	26472758	Jiyoye	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.7762004830278811	[222]	[287]	5	hSpCas9	negative selection	23755
184635372	184635395	4	-	26472758	Jiyoye	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.2004339602773424	[381]	[330]	1	hSpCas9	negative selection	23756
184632350	184632373	4	-	26472758	Jiyoye	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.5540167698351445	[139]	[154]	4	hSpCas9	negative selection	23757
184632334	184632357	4	+	26472758	Jiyoye	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.24139690941615943	[303]	[270]	1	hSpCas9	negative selection	23758
184631073	184631096	4	-	26472758	KBM7	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.7487259356875015	[190,124]	[145,101]	7	hSpCas9	negative selection	214867
184631129	184631152	4	-	26472758	KBM7	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.26770380673288097	[1377,1307]	[867,666]	2	hSpCas9	negative selection	214868
184631883	184631906	4	-	26472758	KBM7	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.6853659929274265	[2366,1622]	[1854,1157]	7	hSpCas9	negative selection	214869
184631147	184631170	4	-	26472758	KBM7	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.18796583710615317	[507,412]	[249,240]	2	hSpCas9	negative selection	214870
184631026	184631049	4	+	26472758	KBM7	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.6131863770918837	[1238,1024]	[767,847]	6	hSpCas9	negative selection	214871
184631111	184631134	4	-	26472758	KBM7	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	1.0547995704743531	[970,756]	[943,741]	9	hSpCas9	negative selection	214872
184631047	184631070	4	+	26472758	KBM7	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.2788949606043255	[632,813]	[296,529]	3	hSpCas9	negative selection	214873
184635372	184635395	4	-	26472758	KBM7	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.4455258680042937	[1372,1021]	[758,758]	5	hSpCas9	negative selection	214874
184632350	184632373	4	-	26472758	KBM7	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.6677137693668682	[487,552]	[380,403]	7	hSpCas9	negative selection	214875
184632334	184632357	4	+	26472758	KBM7	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.5973989195616921	[992,557]	[433,631]	6	hSpCas9	negative selection	214876
184631073	184631096	4	-	26472758	Raji	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.9423242891031031	[73]	[32]	8	hSpCas9	negative selection	405985
184631129	184631152	4	-	26472758	Raji	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	-0.3264736286464045	[642]	[118]	-3	hSpCas9	negative selection	405986
184631883	184631906	4	-	26472758	Raji	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.6746065053230554	[790]	[292]	6	hSpCas9	negative selection	405987
184631147	184631170	4	-	26472758	Raji	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	1.164716710439551	[147]	[76]	8	hSpCas9	negative selection	405988
184631026	184631049	4	+	26472758	Raji	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.6623837980788884	[372]	[136]	6	hSpCas9	negative selection	405989
184631111	184631134	4	-	26472758	Raji	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.06507273051563511	[518]	[125]	0	hSpCas9	negative selection	405990
184631047	184631070	4	+	26472758	Raji	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.05529502422514554	[563]	[135]	0	hSpCas9	negative selection	405991
184635372	184635395	4	-	26472758	Raji	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.2926866379748274	[590]	[167]	2	hSpCas9	negative selection	405992
184632350	184632373	4	-	26472758	Raji	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.42782593015045695	[341]	[58]	-4	hSpCas9	negative selection	405993
184632334	184632357	4	+	26472758	Raji	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	-0.0994288744953904	[613]	[132]	-1	hSpCas9	negative selection	405994
184631073	184631096	4	-	26472758	K562	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.002600807742348943	[161]	[136]	0	hSpCas9	negative selection	597103
184631129	184631152	4	-	26472758	K562	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.443118491748117	[1069]	[1227]	3	hSpCas9	negative selection	597104
184631883	184631906	4	-	26472758	K562	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.8733115522645005	[1476]	[2283]	7	hSpCas9	negative selection	597105
184631147	184631170	4	-	26472758	K562	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	-0.37060100691088915	[290]	[189]	-2	hSpCas9	negative selection	597106
184631026	184631049	4	+	26472758	K562	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.7013205345755258	[933]	[1281]	6	hSpCas9	negative selection	597107
184631111	184631134	4	-	26472758	K562	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.6262893630100914	[824]	[1074]	5	hSpCas9	negative selection	597108
184631047	184631070	4	+	26472758	K562	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.4145423516795814	[806]	[907]	3	hSpCas9	negative selection	597109
184635372	184635395	4	-	26472758	K562	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	1.0740999238357503	[915]	[1627]	8	hSpCas9	negative selection	597110
184632350	184632373	4	-	26472758	K562	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	1.2737626892485912	[364]	[744]	9	hSpCas9	negative selection	597111
184632334	184632357	4	+	26472758	K562	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.8250938699845048	[673]	[1007]	7	hSpCas9	negative selection	597112
184629373	184629396	4	+	26627737	DLD1	viability	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.7496884779652973	[684]	[306,417,357]	7	hSpCas9	negative selection	824634
184629374	184629397	4	+	26627737	DLD1	viability	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.630393912123951	[474]	[237,295,167]	6	hSpCas9	negative selection	824635
184629379	184629402	4	-	26627737	DLD1	viability	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.2564038940113864	[535]	[100,262,233]	2	hSpCas9	negative selection	824636
184629436	184629459	4	+	26627737	DLD1	viability	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.8259970461668389	[581]	[292,475,220]	7	hSpCas9	negative selection	824637
184631057	184631080	4	+	26627737	DLD1	viability	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	0.04061587709588821	[113]	[22,93,0]	0	hSpCas9	negative selection	824638
184629373	184629396	4	+	26627737	GBM cells	viability after 5 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.024444756969544512	[395]	[193,237]	0	hSpCas9	negative selection	906949
184629374	184629397	4	+	26627737	GBM cells	viability after 5 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.201982942521732	[384]	[233,240]	3	hSpCas9	negative selection	906950
184629379	184629402	4	-	26627737	GBM cells	viability after 5 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.11392676585653583	[279]	[183,140]	1	hSpCas9	negative selection	906951
184629436	184629459	4	+	26627737	GBM cells	viability after 5 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.05054509178765609	[387]	[205,224]	0	hSpCas9	negative selection	906952
184631057	184631080	4	+	26627737	GBM cells	viability after 5 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-0.03695578769459895	[87]	[35,55]	0	hSpCas9	negative selection	906953
184629373	184629396	4	+	26627737	GBM cells	viability after 13 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.06402674270464181	[395]	[276,181]	0	hSpCas9	negative selection	989264
184629374	184629397	4	+	26627737	GBM cells	viability after 13 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.6477351138918668	[384]	[318,333]	7	hSpCas9	negative selection	989265
184629379	184629402	4	-	26627737	GBM cells	viability after 13 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.3829801432515841	[279]	[212,185]	5	hSpCas9	negative selection	989266
184629436	184629459	4	+	26627737	GBM cells	viability after 13 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.457152669486548	[387]	[304,275]	6	hSpCas9	negative selection	989267
184631057	184631080	4	+	26627737	GBM cells	viability after 13 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-0.09351271779459358	[87]	[25,59]	-1	hSpCas9	negative selection	989268
184629373	184629396	4	+	26627737	GBM cells	viability after 21 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.02265957356420334	[395]	[240,197]	0	hSpCas9	negative selection	1071579
184629374	184629397	4	+	26627737	GBM cells	viability after 21 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.7785994199200896	[384]	[374,343]	7	hSpCas9	negative selection	1071580
184629379	184629402	4	-	26627737	GBM cells	viability after 21 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.13225288482666797	[279]	[184,149]	1	hSpCas9	negative selection	1071581
184629436	184629459	4	+	26627737	GBM cells	viability after 21 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.7681158389034799	[387]	[370,347]	7	hSpCas9	negative selection	1071582
184631057	184631080	4	+	26627737	GBM cells	viability after 21 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-1.3645553972901256	[87]	[16,19]	-8	hSpCas9	negative selection	1071583
184629373	184629396	4	+	26627737	RPE1	viability after 9 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.30427296691022754	[1561]	[285,537]	-2	hSpCas9	negative selection	1153894
184629374	184629397	4	+	26627737	RPE1	viability after 9 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.569547571773849	[880]	[476,321]	4	hSpCas9	negative selection	1153895
184629379	184629402	4	-	26627737	RPE1	viability after 9 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	-0.33499433257265454	[1335]	[345,312]	-2	hSpCas9	negative selection	1153896
184629436	184629459	4	+	26627737	RPE1	viability after 9 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.05061899550176663	[1585]	[340,657]	0	hSpCas9	negative selection	1153897
184631057	184631080	4	+	26627737	RPE1	viability after 9 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-0.5711523952671607	[385]	[0,184]	-4	hSpCas9	negative selection	1153898
184629373	184629396	4	+	26627737	RPE1	viability after 12 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.23976745532752552	[1561]	[266,448]	-2	hSpCas9	negative selection	1236209
184629374	184629397	4	+	26627737	RPE1	viability after 12 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.48740750451044723	[880]	[376,283]	3	hSpCas9	negative selection	1236210
184629379	184629402	4	-	26627737	RPE1	viability after 12 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	-0.5130963452942554	[1335]	[200,304]	-4	hSpCas9	negative selection	1236211
184629436	184629459	4	+	26627737	RPE1	viability after 12 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.17216840951071055	[1585]	[534,421]	1	hSpCas9	negative selection	1236212
184631057	184631080	4	+	26627737	RPE1	viability after 12 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-1.1079522194735132	[385]	[17,79]	-6	hSpCas9	negative selection	1236213
184629373	184629396	4	+	26627737	RPE1	viability after 15 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.15158455345055988	[1561]	[437,358]	-1	hSpCas9	negative selection	1318524
184629374	184629397	4	+	26627737	RPE1	viability after 15 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.4960015346868414	[880]	[521,186]	3	hSpCas9	negative selection	1318525
184629379	184629402	4	-	26627737	RPE1	viability after 15 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	-0.2613388621084711	[1335]	[297,331]	-2	hSpCas9	negative selection	1318526
184629436	184629459	4	+	26627737	RPE1	viability after 15 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.21552968673697315	[1585]	[608,435]	1	hSpCas9	negative selection	1318527
184631057	184631080	4	+	26627737	RPE1	viability after 15 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-0.8383130165037174	[385]	[28,91]	-5	hSpCas9	negative selection	1318528
184629373	184629396	4	+	26627737	RPE1	viability after 18 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.6445193454016112	[1561]	[215,326]	-4	hSpCas9	negative selection	1400839
184629374	184629397	4	+	26627737	RPE1	viability after 18 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.3557217017570179	[880]	[383,218]	2	hSpCas9	negative selection	1400840
184629379	184629402	4	-	26627737	RPE1	viability after 18 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	-0.47290474375966535	[1335]	[296,219]	-3	hSpCas9	negative selection	1400841
184629436	184629459	4	+	26627737	RPE1	viability after 18 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.32828773260549404	[1585]	[562,509]	2	hSpCas9	negative selection	1400842
184631057	184631080	4	+	26627737	RPE1	viability after 18 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-1.4464291478315179	[385]	[0,77]	-7	hSpCas9	negative selection	1400843
184629373	184629396	4	+	26627737	HeLa	viability after 8 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.6848872958457106	[495]	[271,473,282]	6	hSpCas9	negative selection	1483154
184629374	184629397	4	+	26627737	HeLa	viability after 8 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.30376535503938046	[542]	[408,232,260]	3	hSpCas9	negative selection	1483155
184629379	184629402	4	-	26627737	HeLa	viability after 8 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	-0.24127372290045923	[318]	[154,64,138]	-2	hSpCas9	negative selection	1483156
184629436	184629459	4	+	26627737	HeLa	viability after 8 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.021578155658328768	[915]	[344,396,454]	0	hSpCas9	negative selection	1483157
184631057	184631080	4	+	26627737	HeLa	viability after 8 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-1.4072929499052866	[140]	[44,2,25]	-8	hSpCas9	negative selection	1483158
184629373	184629396	4	+	26627737	HeLa	viability after 12 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.39633465422434133	[495]	[429,184,207]	3	hSpCas9	negative selection	1565469
184629374	184629397	4	+	26627737	HeLa	viability after 12 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.19218543126763582	[542]	[198,307,254]	1	hSpCas9	negative selection	1565470
184629379	184629402	4	-	26627737	HeLa	viability after 12 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.5380531363994984	[318]	[242,141,195]	4	hSpCas9	negative selection	1565471
184629436	184629459	4	+	26627737	HeLa	viability after 12 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.09638092504032936	[915]	[597,196,290]	-1	hSpCas9	negative selection	1565472
184631057	184631080	4	+	26627737	HeLa	viability after 12 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-2.4975603710926864	[140]	[17,11,0]	-9	hSpCas9	negative selection	1565473
184629373	184629396	4	+	26627737	HeLa	viability after 15 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.06170737537896681	[495]	[230,189,210]	0	hSpCas9	negative selection	1647784
184629374	184629397	4	+	26627737	HeLa	viability after 15 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.13586452912642194	[542]	[203,247,279]	1	hSpCas9	negative selection	1647785
184629379	184629402	4	-	26627737	HeLa	viability after 15 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.2392118404202392	[318]	[174,89,197]	2	hSpCas9	negative selection	1647786
184629436	184629459	4	+	26627737	HeLa	viability after 15 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.19133451121854872	[915]	[379,200,403]	-2	hSpCas9	negative selection	1647787
184631057	184631080	4	+	26627737	HeLa	viability after 15 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-1.0651868357597054	[140]	[16,6,60]	-7	hSpCas9	negative selection	1647788
184629373	184629396	4	+	26627737	HeLa	viability after 18 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.05233878542125736	[495]	[146,163,210]	0	hSpCas9	negative selection	1730099
184629374	184629397	4	+	26627737	HeLa	viability after 18 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.13232507735213456	[542]	[139,199,279]	1	hSpCas9	negative selection	1730100
184629379	184629402	4	-	26627737	HeLa	viability after 18 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.2361254672421576	[318]	[117,72,197]	2	hSpCas9	negative selection	1730101
184629436	184629459	4	+	26627737	HeLa	viability after 18 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.21126158116443827	[915]	[244,167,403]	-2	hSpCas9	negative selection	1730102
184631057	184631080	4	+	26627737	HeLa	viability after 18 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-0.9976700016400317	[140]	[12,6,60]	-7	hSpCas9	negative selection	1730103
184629373	184629396	4	+	26627737	HCT116	viability after 6 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.24685417701386653	[804]	[76,122]	-1	hSpCas9	negative selection	1812414
184629374	184629397	4	+	26627737	HCT116	viability after 6 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.2479602161227109	[1037]	[439,57]	1	hSpCas9	negative selection	1812415
184629379	184629402	4	-	26627737	HCT116	viability after 6 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.8410664732253732	[405]	[230,49]	4	hSpCas9	negative selection	1812416
184629436	184629459	4	+	26627737	HCT116	viability after 6 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.1549254897821114	[1015]	[405,51]	0	hSpCas9	negative selection	1812417
184631057	184631080	4	+	26627737	HCT116	viability after 6 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	1.2515447628388539	[45]	[42,2]	6	hSpCas9	negative selection	1812418
184629373	184629396	4	+	26627737	HCT116	viability after 8 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.2127648191530822	[521]	[219,268,254]	-2	hSpCas9	negative selection	1894729
184629374	184629397	4	+	26627737	HCT116	viability after 8 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.4165126168751734	[642]	[252,346,196]	-5	hSpCas9	negative selection	1894730
184629379	184629402	4	-	26627737	HCT116	viability after 8 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.049433020019929885	[218]	[158,152,63]	0	hSpCas9	negative selection	1894731
184629436	184629459	4	+	26627737	HCT116	viability after 8 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.4347173783167505	[655]	[286,194,319]	-5	hSpCas9	negative selection	1894732
184631057	184631080	4	+	26627737	HCT116	viability after 8 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	1.3770497911775323	[25]	[17,31,60]	9	hSpCas9	negative selection	1894733
184629373	184629396	4	+	26627737	HCT116	viability after 9 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.2665423556959567	[804]	[214,292]	2	hSpCas9	negative selection	1977044
184629374	184629397	4	+	26627737	HCT116	viability after 9 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.6323107634620873	[1037]	[213,150]	-4	hSpCas9	negative selection	1977045
184629379	184629402	4	-	26627737	HCT116	viability after 9 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.6435295829103964	[405]	[351,24]	4	hSpCas9	negative selection	1977046
184629436	184629459	4	+	26627737	HCT116	viability after 9 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.3236685944336859	[1015]	[324,350]	2	hSpCas9	negative selection	1977047
184631057	184631080	4	+	26627737	HCT116	viability after 9 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	3.1979214767351265	[45]	[0,200]	9	hSpCas9	negative selection	1977048
184629373	184629396	4	+	26627737	HCT116	viability after 12 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.030424746089292132	[521]	[288,226,286]	0	hSpCas9	negative selection	2059359
184629374	184629397	4	+	26627737	HCT116	viability after 12 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.3885956162033821	[642]	[314,283,170]	-4	hSpCas9	negative selection	2059360
184629379	184629402	4	-	26627737	HCT116	viability after 12 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.8735676645652074	[218]	[169,202,262]	7	hSpCas9	negative selection	2059361
184629436	184629459	4	+	26627737	HCT116	viability after 12 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.3473985531899023	[655]	[160,329,332]	-4	hSpCas9	negative selection	2059362
184631057	184631080	4	+	26627737	HCT116	viability after 12 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	1.6178519425204136	[25]	[73,0,46]	9	hSpCas9	negative selection	2059363
184629373	184629396	4	+	26627737	HCT116	viability after 15 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.4831502722884165	[521]	[210,301,130]	-5	hSpCas9	negative selection	2141674
184629374	184629397	4	+	26627737	HCT116	viability after 15 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.2902930072318447	[642]	[352,247,310]	-3	hSpCas9	negative selection	2141675
184629379	184629402	4	-	26627737	HCT116	viability after 15 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.7800918938179369	[218]	[113,178,340]	6	hSpCas9	negative selection	2141676
184629436	184629459	4	+	26627737	HCT116	viability after 15 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.321141069067451	[655]	[271,321,306]	-3	hSpCas9	negative selection	2141677
184631057	184631080	4	+	26627737	HCT116	viability after 15 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	1.9777011697509765	[25]	[63,48,63]	9	hSpCas9	negative selection	2141678
184629373	184629396	4	+	26627737	HCT116	viability after 18 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.9745051509629916	[521]	[139,168,70]	-7	hSpCas9	negative selection	2223989
184629374	184629397	4	+	26627737	HCT116	viability after 18 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.11800167796506655	[642]	[358,250,249]	-1	hSpCas9	negative selection	2223990
184629379	184629402	4	-	26627737	HCT116	viability after 18 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.5633356269470458	[218]	[114,107,253]	5	hSpCas9	negative selection	2223991
184629436	184629459	4	+	26627737	HCT116	viability after 18 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.1333756374291597	[655]	[159,242,475]	-1	hSpCas9	negative selection	2223992
184631057	184631080	4	+	26627737	HCT116	viability after 18 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	1.3289215945864994	[25]	[48,4,42]	8	hSpCas9	negative selection	2223993
184632267	184632290	4	-	24336569	HL60	viability	ATTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	-0.5192079227669057	[1109]	[1638]	-5	hSpCas9	negative selection	2254476
184632334	184632357	4	+	24336569	HL60	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	-0.7903291592871369	[643]	[787]	-6	hSpCas9	negative selection	2254477
184632349	184632372	4	-	24336569	HL60	viability	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	-0.33259641740639845	[675]	[1135]	-3	hSpCas9	negative selection	2254478
184632378	184632401	4	-	24336569	HL60	viability	CAAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	-0.9857989913336584	[422]	[451]	-7	hSpCas9	negative selection	2254479
184632383	184632406	4	-	24336569	HL60	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.18445137464143901	[666]	[1603]	1	hSpCas9	negative selection	2254480
184635326	184635349	4	+	24336569	HL60	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.4470850911869934	[338]	[977]	4	hSpCas9	negative selection	2254481
184635372	184635395	4	-	24336569	HL60	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	-0.24857408646415458	[511]	[911]	-2	hSpCas9	negative selection	2254482
184635383	184635406	4	-	24336569	HL60	viability	GGAAGCGAATCAATGGACTCTGG	CASP3	ENSG00000164305	-0.22456499159693588	[735]	[1332]	-2	hSpCas9	negative selection	2254483
184635390	184635413	4	-	24336569	HL60	viability	CATACATGGAAGCGAATCAATGG	CASP3	ENSG00000164305	-0.7686591436167135	[697]	[866]	-6	hSpCas9	negative selection	2254484
184635404	184635427	4	-	24336569	HL60	viability	CTAAACAGAAAGATCATACATGG	CASP3	ENSG00000164305	-0.22539389353826406	[494]	[895]	-2	hSpCas9	negative selection	2254485
184632267	184632290	4	-	24336569	KBM7	viability	ATTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	-0.26691638340391566	[936]	[2123]	-2	hSpCas9	negative selection	2321653
184632334	184632357	4	+	24336569	KBM7	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.8444065829810403	[184]	[905]	7	hSpCas9	negative selection	2321654
184632349	184632372	4	-	24336569	KBM7	viability	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	0.4332735381581128	[409]	[1509]	4	hSpCas9	negative selection	2321655
184632378	184632401	4	-	24336569	KBM7	viability	CAAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	-0.7914556669064875	[355]	[560]	-6	hSpCas9	negative selection	2321656
184632383	184632406	4	-	24336569	KBM7	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.7576720919661715	[380]	[1756]	6	hSpCas9	negative selection	2321657
184635326	184635349	4	+	24336569	KBM7	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.051653430146389734	[519]	[1469]	0	hSpCas9	negative selection	2321658
184635372	184635395	4	-	24336569	KBM7	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.4083698333964606	[391]	[1418]	4	hSpCas9	negative selection	2321659
184635383	184635406	4	-	24336569	KBM7	viability	GGAAGCGAATCAATGGACTCTGG	CASP3	ENSG00000164305	0.2515009847795946	[489]	[1590]	2	hSpCas9	negative selection	2321660
184635390	184635413	4	-	24336569	KBM7	viability	CATACATGGAAGCGAATCAATGG	CASP3	ENSG00000164305	-0.3640385010061793	[519]	[1101]	-3	hSpCas9	negative selection	2321661
184635404	184635427	4	-	24336569	KBM7	viability	CTAAACAGAAAGATCATACATGG	CASP3	ENSG00000164305	0.7617797549547831	[412]	[1909]	6	hSpCas9	negative selection	2321662
184635390	184635415	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	ATCATACATGGAAGCGAATCAATGG	CASP3	ENSG00000164305	10.712640654347991	[4041,4765,3652]	[42,8260,4]	9	hSpCas9	positive selection	2380639
184635390	184635415	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	ATCATACATGGAAGCGAATCAATGG	CASP3	ENSG00000164305	10.712640654347991	[4041,4765,3652]	[42,8260,4]	9	hSpCas9	positive selection	2380640
184635390	184635415	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	ATCATACATGGAAGCGAATCAATGG	CASP3	ENSG00000164305	10.712640654347991	[4041,4765,3652]	[42,8260,4]	9	hSpCas9	positive selection	2380641
184638405	184638429	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	ATTCAAAATCCATTAAAAATTTGG	CASP3	ENSG00000164305	12.647295473493159	[4765,4969,5080]	[65,15230,22482]	9	hSpCas9	positive selection	2380642
184638405	184638429	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	ATTCAAAATCCATTAAAAATTTGG	CASP3	ENSG00000164305	12.647295473493159	[4765,4969,5080]	[65,15230,22482]	9	hSpCas9	positive selection	2380643
184638405	184638429	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	ATTCAAAATCCATTAAAAATTTGG	CASP3	ENSG00000164305	12.647295473493159	[4765,4969,5080]	[65,15230,22482]	9	hSpCas9	positive selection	2380644
184635339	184635365	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TTATAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-0.4542270262601509	[8942,7681,7592]	[4,0,0]	-4	hSpCas9	positive selection	2380645
184635339	184635365	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TTATAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-0.4542270262601509	[8942,7681,7592]	[4,0,0]	-4	hSpCas9	positive selection	2380646
184635339	184635365	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TTATAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-0.4542270262601509	[8942,7681,7592]	[4,0,0]	-4	hSpCas9	positive selection	2380647
184635390	184635415	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ATCATACATGGAAGCGAATCAATGG	CASP3	ENSG00000164305	0.2763136513742682	[4041,4765,3652]	[0,1,2]	0	hSpCas9	positive selection	2381777
184635390	184635415	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ATCATACATGGAAGCGAATCAATGG	CASP3	ENSG00000164305	0.2763136513742682	[4041,4765,3652]	[0,1,2]	0	hSpCas9	positive selection	2381778
184635390	184635415	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ATCATACATGGAAGCGAATCAATGG	CASP3	ENSG00000164305	0.2763136513742682	[4041,4765,3652]	[0,1,2]	0	hSpCas9	positive selection	2381779
184638405	184638429	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ATTCAAAATCCATTAAAAATTTGG	CASP3	ENSG00000164305	6.416245323639136	[4765,4969,5080]	[285,154,61]	8	hSpCas9	positive selection	2381780
184638405	184638429	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ATTCAAAATCCATTAAAAATTTGG	CASP3	ENSG00000164305	6.416245323639136	[4765,4969,5080]	[285,154,61]	8	hSpCas9	positive selection	2381781
184638405	184638429	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ATTCAAAATCCATTAAAAATTTGG	CASP3	ENSG00000164305	6.416245323639136	[4765,4969,5080]	[285,154,61]	8	hSpCas9	positive selection	2381782
184635339	184635365	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TTATAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	10.303999702143573	[8942,7681,7592]	[5347,3,6773]	9	hSpCas9	positive selection	2381783
184635339	184635365	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TTATAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	10.303999702143573	[8942,7681,7592]	[5347,3,6773]	9	hSpCas9	positive selection	2381784
184635339	184635365	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TTATAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	10.303999702143573	[8942,7681,7592]	[5347,3,6773]	9	hSpCas9	positive selection	2381785
184649435	184649458	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCGCGGAAGCAGTGCAGACGCGG	CASP3	ENSG00000164305	-1.408606422060835	[96,82]	[7,5]	-7	dCas9-VP64	positive selection	2467495
184649502	184649525	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCGAGGGGCCGACAGGGGCGG	CASP3	ENSG00000164305	0.484164281385898	[105,9]	[1,33]	2	dCas9-VP64	positive selection	2467496
184649458	184649481	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGCACATCTCCCGGCGGCGGG	CASP3	ENSG00000164305	2.173125561213762	[1,10]	[5,6]	7	dCas9-VP64	positive selection	2467497
184649435	184649458	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCGCGGAAGCAGTGCAGACGCGG	CASP3	ENSG00000164305	0.40776027600948517	[78,80]	[52,16]	3	dCas9-VP64	positive selection	2562750
184649502	184649525	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCGAGGGGCCGACAGGGGCGG	CASP3	ENSG00000164305	-1.082492959435925	[50,33]	[7,3]	-9	dCas9-VP64	positive selection	2562751
184649458	184649481	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGCACATCTCCCGGCGGCGGG	CASP3	ENSG00000164305	0.6925566996850177	[36,35]	[32,5]	5	dCas9-VP64	positive selection	2562752
184635354	184635377	4	+	27013184	SW480	treatment with recombinant TRAIL	CCATTTTATAACTGTTGTCCAGG	CASP3	ENSG00000164305	0.23582792683413878	[445,535]	[296,176]	1	hSpCas9	positive selection	2963261
184635355	184635378	4	+	27013184	SW480	treatment with recombinant TRAIL	CATTTTATAACTGTTGTCCAGGG	CASP3	ENSG00000164305	3.5671922227490906	[59,143]	[474,541]	9	hSpCas9	positive selection	2963262
184638429	184638452	4	-	27013184	SW480	treatment with recombinant TRAIL	GGAGAACACTGAAAACTCAGTGG	CASP3	ENSG00000164305	2.734141227435635	[75,190]	[158,666]	9	hSpCas9	positive selection	2963265
184638450	184638473	4	-	27013184	SW480	treatment with recombinant TRAIL	CTAGTTAATAAAGGTATCCATGG	CASP3	ENSG00000164305	-0.9444217990253185	[67,22]	[8,12]	-4	hSpCas9	positive selection	2963266
184632334	184632357	4	+	27013184	SW480	treatment with recombinant TRAIL	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	2.8800982704181997	[334,293]	[727,1398]	9	hSpCas9	positive selection	2963267
184632379	184632402	4	+	27013184	SW480	treatment with recombinant TRAIL	CAGACCGAGATGTCATTCCTTGG	CASP3	ENSG00000164305	1.858471937255069	[384,452]	[678,610]	8	hSpCas9	positive selection	2963268
184629391	184629414	4	-	27013184	SW480	treatment with recombinant TRAIL	ATTTATGCACATTCTTACCCGGG	CASP3	ENSG00000164305	2.8947062345340457	[685,780]	[2325,2360]	9	hSpCas9	positive selection	2963269
184629392	184629415	4	-	27013184	SW480	treatment with recombinant TRAIL	AATTTATGCACATTCTTACCCGG	CASP3	ENSG00000164305	-0.08251135580616009	[426,268]	[76,240]	0	hSpCas9	positive selection	2963270
184629464	184629487	4	-	27013184	SW480	treatment with recombinant TRAIL	GAAATTCAAAGGATGGCTCCTGG	CASP3	ENSG00000164305	0.46354545727306784	[72,127]	[33,92]	2	hSpCas9	positive selection	2963271
184629471	184629494	4	-	27013184	SW480	treatment with recombinant TRAIL	TCTTGGCGAAATTCAAAGGATGG	CASP3	ENSG00000164305	3.029897856958277	[89,83]	[262,370]	9	hSpCas9	positive selection	2963272
184629475	184629498	4	-	27013184	SW480	treatment with recombinant TRAIL	TTATTCTTGGCGAAATTCAAAGG	CASP3	ENSG00000164305	0.1612585485004952	[118,197]	[87,55]	0	hSpCas9	positive selection	2963273
184629488	184629511	4	-	27013184	SW480	treatment with recombinant TRAIL	GCCTTTTAGGTTATTATTCTTGG	CASP3	ENSG00000164305	-0.6925679120473596	[45,92]	[17,17]	-3	hSpCas9	positive selection	2963274
184638433	184638456	4	+	27013184	SW480	treatment with recombinant TRAIL	TGAGTTTTCAGTGTTCTCCATGG	CASP3	ENSG00000164305	2.7967194004903497	[98,177]	[398,412]	9	hSpCas9	positive selection	2963275
184631790	184631813	4	-	27013184	SW480	treatment with recombinant TRAIL	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	2.787116663709199	[207,157]	[346,842]	9	hSpCas9	positive selection	2963276
184631874	184631897	4	-	27013184	SW480	treatment with recombinant TRAIL	CTTCTGAGCCATGGTGAAGAAGG	CASP3	ENSG00000164305	5.517089545305843	[2,7]	[126,71]	9	hSpCas9	positive selection	2963277
184632349	184632372	4	-	27013184	SW480	treatment with recombinant TRAIL	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	2.1068475498118167	[192,183]	[268,467]	8	hSpCas9	positive selection	2963278
184632350	184632373	4	-	27013184	SW480	treatment with recombinant TRAIL	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	2.7305500205139817	[61,46]	[131,194]	9	hSpCas9	positive selection	2963279
184632378	184632401	4	-	27013184	SW480	treatment with recombinant TRAIL	CAAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	1.9954316757507986	[75,187]	[121,355]	8	hSpCas9	positive selection	2963280
184635293	184635316	4	-	27013184	SW480	treatment with recombinant TRAIL	AAGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	1.7386867281558747	[68,76]	[64,160]	7	hSpCas9	positive selection	2963281
184632383	184632406	4	-	27013184	SW480	treatment with recombinant TRAIL	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	2.759211683391479	[51,157]	[285,302]	9	hSpCas9	positive selection	2963282
184632396	184632419	4	-	27013184	SW480	treatment with recombinant TRAIL	AAGTAATTCTTTCTGTTCCAAGG	CASP3	ENSG00000164305	1.7650703661664409	[442,344]	[438,790]	7	hSpCas9	positive selection	2963283
184629404	184629427	4	+	27013184	SW480	treatment with recombinant TRAIL	GTGCATAAATTCAAGCTTGTCGG	CASP3	ENSG00000164305	1.7304601051885755	[54,96]	[61,168]	7	hSpCas9	positive selection	2963284
184635354	184635377	4	-	27013184	SW480	treatment with recombinant TRAIL	CCTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	-2.1175215651440142	[10,30]	[1,1]	-7	hSpCas9	positive selection	2963285
184629422	184629445	4	+	27013184	SW480	treatment with recombinant TRAIL	GTCGGCATACTGTTTCAGCATGG	CASP3	ENSG00000164305	2.048115741414013	[340,164]	[261,754]	8	hSpCas9	positive selection	2963286
184635372	184635395	4	-	27013184	SW480	treatment with recombinant TRAIL	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	4.276056529820545	[726,782]	[6805,5558]	9	hSpCas9	positive selection	2963287
184629436	184629459	4	+	27013184	SW480	treatment with recombinant TRAIL	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	2.96756069918535	[46,35]	[182,82]	9	hSpCas9	positive selection	2963288
184635383	184635406	4	-	27013184	SW480	treatment with recombinant TRAIL	GGAAGCGAATCAATGGACTCTGG	CASP3	ENSG00000164305	1.0351059055560485	[43,50]	[30,56]	5	hSpCas9	positive selection	2963289
184629487	184629510	4	+	27013184	SW480	treatment with recombinant TRAIL	GCCAAGAATAATAACCTAAAAGG	CASP3	ENSG00000164305	-1.3515979962475053	[103,287]	[6,66]	-6	hSpCas9	positive selection	2963290
184635390	184635413	4	-	27013184	SW480	treatment with recombinant TRAIL	CATACATGGAAGCGAATCAATGG	CASP3	ENSG00000164305	-1.6475978785272374	[24,1]	[1,1]	-6	hSpCas9	positive selection	2963291
184635404	184635427	4	-	27013184	SW480	treatment with recombinant TRAIL	CTAAACAGAAAGATCATACATGG	CASP3	ENSG00000164305	2.1136459088732593	[19,27]	[25,69]	8	hSpCas9	positive selection	2963292
184632335	184632358	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.1602979643515015	[4,4]	[4,3]	3	hSpCas9	positive selection	2976411
184638429	184638452	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGAACACTGAAAACTCAGTGG	CASP3	ENSG00000164305	0.1914056503108536	[3,3]	[3,3]	4	hSpCas9	positive selection	2976412
184631883	184631906	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.2486680421261082	[3,4]	[4,4]	5	hSpCas9	positive selection	2976413
184632349	184632372	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	0.33706767585957176	[4,4]	[4,5]	7	hSpCas9	positive selection	2976414
184632335	184632358	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.2508333100482134	[4,4]	[4,3]	4	hSpCas9	positive selection	3044269
184638429	184638452	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGAACACTGAAAACTCAGTGG	CASP3	ENSG00000164305	1.053042540292041	[3,3]	[2,6]	9	hSpCas9	positive selection	3044270
184631883	184631906	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.08331099730809777	[3,3]	[2,2]	1	hSpCas9	positive selection	3044271
184632349	184632372	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	0.14827658814842182	[4,4]	[4,3]	2	hSpCas9	positive selection	3044272
184635372	184635395		-	24336571	A375	resistance to PLX after 7 days	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.11200901246070244	[8,7]	[8,8]	4	hSpCas9	positive selection	3160728
184635326	184635349		+	24336571	A375	resistance to PLX after 7 days	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.07226825757468922	[10,8]	[9,11]	2	hSpCas9	positive selection	3160729
184635339	184635362		-	24336571	A375	resistance to PLX after 7 days	TAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-0.22113015862231455	[5,5]	[5,4]	-6	hSpCas9	positive selection	3160730
184638397	184638420		+	24336571	A375	resistance to PLX after 7 days	TCACGGTTCCAAATTTTTAATGG	CASP3	ENSG00000164305	0.05409502051220172	[3,5]	[4,5]	2	hSpCas9	positive selection	3160731
184638433	184638456		+	24336571	A375	resistance to PLX after 7 days	TGAGTTTTCAGTGTTCTCCATGG	CASP3	ENSG00000164305	-0.040631595710049484	[20,18]	[19,17]	-1	hSpCas9	positive selection	3160732
184635372	184635395		-	24336571	A375	resistance to PLX after 14 days	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.15790575053129674	[8,4]	[2,3]	1	hSpCas9	positive selection	3218521
184635326	184635349		+	24336571	A375	resistance to PLX after 14 days	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.4081310344692348	[9,11]	[7,5]	4	hSpCas9	positive selection	3218522
184635339	184635362		-	24336571	A375	resistance to PLX after 14 days	TAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.19552049735971644	[4,2]	[1,1]	2	hSpCas9	positive selection	3218523
184638397	184638420		+	24336571	A375	resistance to PLX after 14 days	TCACGGTTCCAAATTTTTAATGG	CASP3	ENSG00000164305	0.11073917213427387	[3,6]	[2,2]	1	hSpCas9	positive selection	3218524
184638433	184638456		+	24336571	A375	resistance to PLX after 14 days	TGAGTTTTCAGTGTTCTCCATGG	CASP3	ENSG00000164305	-0.3310787313501191	[22,14]	[6,6]	-4	hSpCas9	positive selection	3218525
184635372	184635395		-	24336571	A375	viability after 7 days	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	-0.35274202336197424	[10]	[8,7]	-5	hSpCas9	negative selection	3276314
184635326	184635349		+	24336571	A375	viability after 7 days	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	-0.1747983687366654	[11]	[10,8]	-2	hSpCas9	negative selection	3276315
184635339	184635362		-	24336571	A375	viability after 7 days	TAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-0.39019376217176227	[8]	[5,5]	-5	hSpCas9	negative selection	3276316
184638397	184638420		+	24336571	A375	viability after 7 days	TCACGGTTCCAAATTTTTAATGG	CASP3	ENSG00000164305	-0.3495324158406866	[6]	[3,5]	-5	hSpCas9	negative selection	3276317
184638433	184638456		+	24336571	A375	viability after 7 days	TGAGTTTTCAGTGTTCTCCATGG	CASP3	ENSG00000164305	-0.008730817708085592	[20]	[20,18]	0	hSpCas9	negative selection	3276318
184635372	184635395		-	24336571	A375	viability after 14 days	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	-0.5884206405225848	[10]	[8,4]	-6	hSpCas9	negative selection	3334107
184635326	184635349		+	24336571	A375	viability after 14 days	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	-0.036416331765121324	[11]	[9,11]	0	hSpCas9	negative selection	3334108
184635339	184635362		-	24336571	A375	viability after 14 days	TAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-1.0373850949545254	[8]	[4,2]	-8	hSpCas9	negative selection	3334109
184638397	184638420		+	24336571	A375	viability after 14 days	TCACGGTTCCAAATTTTTAATGG	CASP3	ENSG00000164305	-0.2573219365800291	[6]	[3,6]	-3	hSpCas9	negative selection	3334110
184638433	184638456		+	24336571	A375	viability after 14 days	TGAGTTTTCAGTGTTCTCCATGG	CASP3	ENSG00000164305	-0.050653712305737786	[20]	[22,14]	0	hSpCas9	negative selection	3334111
184632350	184632373	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.6947773888765028	[192,302]	[0,0]	-5	hSpCas9	positive selection	3341121
184635326	184635349	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	-1.0146554916540915	[325,291]	[0,0]	-6	hSpCas9	positive selection	3341122
184635372	184635395	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.5935239639339417	[84,117]	[0,0]	3	hSpCas9	positive selection	3341123
184632383	184632406	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	-1.36838263161863	[394,394]	[0,0]	-8	hSpCas9	positive selection	3360369
184631790	184631813	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	0.1280431945008686	[139,139]	[0,0]	0	hSpCas9	positive selection	3360370
184631762	184631785	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	7.255403899314807	[750,750]	[749,749]	9	hSpCas9	positive selection	3360371
184632334	184632357	4	+	26780180	HT29	viability (Avana library 4 designs)	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.198547722539392	[]	[]	0	hSpCas9	negative selection	3412692
184638429	184638452	4	-	26780180	HT29	viability (Avana library 4 designs)	GGAGAACACTGAAAACTCAGTGG	CASP3	ENSG00000164305	0.381166591340028	[]	[]	1	hSpCas9	negative selection	3412693
184631883	184631906	4	-	26780180	HT29	viability (Avana library 4 designs)	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.847064178763785	[]	[]	3	hSpCas9	negative selection	3412694
184632349	184632372	4	-	26780180	HT29	viability (Avana library 4 designs)	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	-0.130684585349754	[]	[]	-2	hSpCas9	negative selection	3412695
184632334	184632357	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	2.94221994637201	[]	[]	4	hSpCas9	negative selection	3488286
184631883	184631906	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	2.27368137724008	[]	[]	3	hSpCas9	negative selection	3488287
184632349	184632372	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	0.511003332371028	[]	[]	0	hSpCas9	negative selection	3488288
184638429	184638452	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGAACACTGAAAACTCAGTGG	CASP3	ENSG00000164305	-10.2164689307057	[]	[]	-7	hSpCas9	negative selection	3488289
184635404	184635427	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTAAACAGAAAGATCATACATGG	CASP3	ENSG00000164305	-9.94633807417255	[]	[]	-7	hSpCas9	negative selection	3488290
184635372	184635395	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.139020147023153	[]	[]	0	hSpCas9	negative selection	3488291
184632334	184632357	4	+	26780180	A375	viability (Avana lentiGuide)	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	-4.13412142635296	[]	[]	-7	hSpCas9	negative selection	3596945
184631883	184631906	4	-	26780180	A375	viability (Avana lentiGuide)	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	-0.803573836739011	[]	[]	-1	hSpCas9	negative selection	3596946
184632349	184632372	4	-	26780180	A375	viability (Avana lentiGuide)	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	-1.23764953173147	[]	[]	-2	hSpCas9	negative selection	3596947
184638429	184638452	4	-	26780180	A375	viability (Avana lentiGuide)	GGAGAACACTGAAAACTCAGTGG	CASP3	ENSG00000164305	9.21788779916707	[]	[]	6	hSpCas9	negative selection	3596948
184635404	184635427	4	-	26780180	A375	viability (Avana lentiGuide)	CTAAACAGAAAGATCATACATGG	CASP3	ENSG00000164305	-1.27835864236321	[]	[]	-2	hSpCas9	negative selection	3596949
184635372	184635395	4	-	26780180	A375	viability (Avana lentiGuide)	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	-0.897925509243533	[]	[]	-1	hSpCas9	negative selection	3596950
184632334	184632357	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.17325304628349725	[6]	[6,6]	5	hSpCas9	positive selection	3705604
184631883	184631906	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.12447865478069836	[5]	[6,5]	3	hSpCas9	positive selection	3705605
184632349	184632372	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	-0.1635878938855165	[5]	[6,3]	-3	hSpCas9	positive selection	3705606
184638429	184638452	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGAACACTGAAAACTCAGTGG	CASP3	ENSG00000164305	-0.9389504670223323	[4]	[1,1]	-8	hSpCas9	positive selection	3705607
184635404	184635427	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAAACAGAAAGATCATACATGG	CASP3	ENSG00000164305	-1.01121164601879	[9]	[3,3]	-8	hSpCas9	positive selection	3705608
184635372	184635395	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	-0.059816017051106035	[5]	[6,4]	-1	hSpCas9	positive selection	3705609
184632334	184632357	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.3126329594992238	[6]	[6,6]	8	hSpCas9	positive selection	3814211
184631883	184631906	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	-0.16072780712506265	[6]	[4,4]	-2	hSpCas9	positive selection	3814212
184632349	184632372	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCGATGCAGCAAACCTCAGGG	CASP3	ENSG00000164305	0.15258919210230276	[6]	[6,6]	3	hSpCas9	positive selection	3814213
184638429	184638452	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGAACACTGAAAACTCAGTGG	CASP3	ENSG00000164305	-0.37667884697543963	[4]	[1,3]	-5	hSpCas9	positive selection	3814214
184635404	184635427	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAAACAGAAAGATCATACATGG	CASP3	ENSG00000164305	0.3270386607262212	[5]	[6,5]	8	hSpCas9	positive selection	3814215
184635372	184635395	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.11134812400520176	[6]	[6,4]	2	hSpCas9	positive selection	3814216
184635372	184635395	4	-	26780180	A375	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	1.31253851582647	[]	[]	7	hSpCas9	negative selection	3922511
184632350	184632373	4	-	26780180	A375	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.970180883613473	[]	[]	4	hSpCas9	negative selection	3922512
184635326	184635349	4	+	26780180	A375	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	1.44269397839905	[]	[]	8	hSpCas9	negative selection	3922513
184631790	184631813	4	-	26780180	A375	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	0.807703712900369	[]	[]	3	hSpCas9	negative selection	3922514
184631762	184631785	4	+	26780180	A375	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.999740416984994	[]	[]	4	hSpCas9	negative selection	3922515
184632383	184632406	4	-	26780180	A375	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	1.10205106625965	[]	[]	5	hSpCas9	negative selection	3922516
184635372	184635395	4	-	26780180	HT29	viability (GeCKOv2 library)	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	1.09433816867736	[]	[]	5	hSpCas9	negative selection	4030477
184632350	184632373	4	-	26780180	HT29	viability (GeCKOv2 library)	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	1.70201029732292	[]	[]	8	hSpCas9	negative selection	4030478
184635326	184635349	4	+	26780180	HT29	viability (GeCKOv2 library)	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.86278447446398	[]	[]	3	hSpCas9	negative selection	4030479
184631790	184631813	4	-	26780180	HT29	viability (GeCKOv2 library)	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	1.59710880352223	[]	[]	8	hSpCas9	negative selection	4030480
184631762	184631785	4	+	26780180	HT29	viability (GeCKOv2 library)	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	1.20665329404236	[]	[]	6	hSpCas9	negative selection	4030481
184632383	184632406	4	-	26780180	HT29	viability (GeCKOv2 library)	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.512366903839898	[]	[]	1	hSpCas9	negative selection	4030482
184635372	184635395	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	-0.26917125962183974	[3]	[1,1]	-6	hSpCas9	positive selection	4188821
184635326	184635349	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.12503145044233155	[3]	[1,2]	3	hSpCas9	positive selection	4188822
184635339	184635362	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-0.4535487049178777	[2]	[1,0]	-8	hSpCas9	positive selection	4188823
184638397	184638420	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCACGGTTCCAAATTTTTAATGG	CASP3	ENSG00000164305	-0.1133222465045362	[2]	[1,1]	-3	hSpCas9	positive selection	4188824
184638433	184638456	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAGTTTTCAGTGTTCTCCATGG	CASP3	ENSG00000164305	0.022654187370201112	[4]	[2,2]	0	hSpCas9	positive selection	4188825
184635372	184635395	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	1.0221146716530283	[3]	[0,2,1,4]	7	hSpCas9	positive selection	4252843
184635326	184635349	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.19155362622868416	[3]	[2,0,5,0]	1	hSpCas9	positive selection	4252844
184635339	184635362	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.17283752480548206	[2]	[2,0,1,0]	1	hSpCas9	positive selection	4252845
184638397	184638420	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCACGGTTCCAAATTTTTAATGG	CASP3	ENSG00000164305	0.7530314986662425	[1]	[1,2,1,0]	5	hSpCas9	positive selection	4252846
184638433	184638456	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAGTTTTCAGTGTTCTCCATGG	CASP3	ENSG00000164305	0.6895526152244359	[4]	[1,2,2,2]	4	hSpCas9	positive selection	4252847
184632350	184632373	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.3491087886181412	[3]	[2,1]	-6	hSpCas9	positive selection	4261009
184635326	184635349	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	-0.04195979986382037	[4]	[3,2]	-1	hSpCas9	positive selection	4261010
184635372	184635395	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.3294975221945884	[2]	[3,2]	6	hSpCas9	positive selection	4261011
184632383	184632406	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.2396712053124971	[3]	[3,2]	5	hSpCas9	positive selection	4325287
184631790	184631813	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.11522141523256726	[2]	[2,0]	-2	hSpCas9	positive selection	4325288
184631762	184631785	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.1804249564330932	[5]	[4,4]	3	hSpCas9	positive selection	4325289
184632267	184632289	4	-	27760321	OCIAML3	viability	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	0.3716991029610687	[309,290]	[213,421]	4	hSpCas9	negative selection	4385800
184632378	184632400	4	-	27760321	OCIAML3	viability	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.618726599979808	[492,430]	[428,715]	7	hSpCas9	negative selection	4385801
184635293	184635315	4	-	27760321	OCIAML3	viability	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-0.8612388130902078	[118,99]	[49,42]	-7	hSpCas9	negative selection	4385802
184635339	184635361	4	-	27760321	OCIAML3	viability	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.5971819137806196	[39,27]	[34,45]	7	hSpCas9	negative selection	4385803
184635354	184635376	4	-	27760321	OCIAML3	viability	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	2.6963512785850727	[17,4]	[27,91]	9	hSpCas9	negative selection	4385804
184632267	184632289	4	-	27760321	OCIAML2	viability	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	-0.391068594945602	[309,290]	[153,226]	-4	hSpCas9	negative selection	4469263
184632378	184632400	4	-	27760321	OCIAML2	viability	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.6042480866964741	[492,430]	[540,600]	7	hSpCas9	negative selection	4469264
184635293	184635315	4	-	27760321	OCIAML2	viability	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	0.6550820860058	[118,99]	[103,184]	8	hSpCas9	negative selection	4469265
184635339	184635361	4	-	27760321	OCIAML2	viability	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.13031661856377452	[39,27]	[21,39]	1	hSpCas9	negative selection	4469266
184635354	184635376	4	-	27760321	OCIAML2	viability	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	-0.5414964468837189	[17,4]	[9,0]	-6	hSpCas9	negative selection	4469267
184632267	184632289	4	-	27760321	MV411	viability	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	0.9422095270111993	[309,290]	[248,579]	7	hSpCas9	negative selection	4552726
184632378	184632400	4	-	27760321	MV411	viability	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	1.3880457481081558	[492,430]	[981,516]	8	hSpCas9	negative selection	4552727
184635293	184635315	4	-	27760321	MV411	viability	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	0.8346382596636912	[118,99]	[95,176]	6	hSpCas9	negative selection	4552728
184635339	184635361	4	-	27760321	MV411	viability	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.9884974859689066	[39,27]	[65,10]	7	hSpCas9	negative selection	4552729
184635354	184635376	4	-	27760321	MV411	viability	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	4.444112611211798	[17,4]	[0,393]	9	hSpCas9	negative selection	4552730
184632267	184632289	4	-	27760321	HL60	viability	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	0.8893296671626776	[309,290]	[421,489]	8	hSpCas9	negative selection	4636189
184632378	184632400	4	-	27760321	HL60	viability	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.023557630320579726	[492,430]	[324,443]	0	hSpCas9	negative selection	4636190
184635293	184635315	4	-	27760321	HL60	viability	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-0.5012058345876884	[118,99]	[77,46]	-5	hSpCas9	negative selection	4636191
184635339	184635361	4	-	27760321	HL60	viability	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.3775534305235344	[39,27]	[24,46]	5	hSpCas9	negative selection	4636192
184635354	184635376	4	-	27760321	HL60	viability	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	-3.1681741473632323	[17,4]	[0,0]	-9	hSpCas9	negative selection	4636193
184632267	184632289	4	-	27760321	HT1080	viability	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	0.2876155777413193	[290,226]	[92,161]	1	hSpCas9	negative selection	4719652
184632378	184632400	4	-	27760321	HT1080	viability	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	1.676452664123388	[430,336]	[204,799]	8	hSpCas9	negative selection	4719653
184635293	184635315	4	-	27760321	HT1080	viability	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	1.6202287600549803	[99,77]	[150,62]	8	hSpCas9	negative selection	4719654
184635339	184635361	4	-	27760321	HT1080	viability	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.7496762502959853	[27,21]	[0,33]	4	hSpCas9	negative selection	4719655
184635354	184635376	4	-	27760321	HT1080	viability	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	-0.8443172389209588	[4,3]	[0,0]	-4	hSpCas9	negative selection	4719656
184632267	184632289	4	-	27760321	HT29	viability after 7 days	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	-0.2783304771877443	[290,226]	[224,372,219]	-4	hSpCas9	negative selection	4803115
184632378	184632400	4	-	27760321	HT29	viability after 7 days	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.42506263472673067	[430,336]	[636,709,637]	6	hSpCas9	negative selection	4803116
184635293	184635315	4	-	27760321	HT29	viability after 7 days	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-1.148515157028418	[99,77]	[58,18,76]	-8	hSpCas9	negative selection	4803117
184635339	184635361	4	-	27760321	HT29	viability after 7 days	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-0.11097843592749035	[27,21]	[61,5,25]	-2	hSpCas9	negative selection	4803118
184635354	184635376	4	-	27760321	HT29	viability after 7 days	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	-0.881543251793091	[4,3]	[0,0,6]	-8	hSpCas9	negative selection	4803119
184632267	184632289	4	-	27760321	HT29	viability after 25 days	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	0.25203139167030625	[290,226]	[281,403,377]	2	hSpCas9	negative selection	4886578
184632378	184632400	4	-	27760321	HT29	viability after 25 days	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.44874082384072245	[430,336]	[473,739,588]	5	hSpCas9	negative selection	4886579
184635293	184635315	4	-	27760321	HT29	viability after 25 days	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-1.3241882708015722	[99,77]	[36,35,49]	-7	hSpCas9	negative selection	4886580
184635339	184635361	4	-	27760321	HT29	viability after 25 days	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.1677638241097612	[27,21]	[19,27,50]	1	hSpCas9	negative selection	4886581
184635354	184635376	4	-	27760321	HT29	viability after 25 days	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	-0.3613201750826631	[4,3]	[5,0,4]	-4	hSpCas9	negative selection	4886582
184632267	184632289	4	-	27760321	HT29	viability after 22 days	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	0.2537732757523359	[290,226]	[408,360,298]	2	hSpCas9	negative selection	4970041
184632378	184632400	4	-	27760321	HT29	viability after 22 days	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.1046093159713708	[430,336]	[411,526,494]	1	hSpCas9	negative selection	4970042
184635293	184635315	4	-	27760321	HT29	viability after 22 days	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-2.1546133344674545	[99,77]	[5,17,45]	-8	hSpCas9	negative selection	4970043
184635339	184635361	4	-	27760321	HT29	viability after 22 days	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.6038303080630594	[27,21]	[13,35,82]	6	hSpCas9	negative selection	4970044
184635354	184635376	4	-	27760321	HT29	viability after 22 days	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	0.01905462172064354	[4,3]	[1,0,12]	0	hSpCas9	negative selection	4970045
184632267	184632289	4	-	27760321	HT29	viability after 19 days	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	0.5216372915437307	[290,226]	[600,192,496]	5	hSpCas9	negative selection	5053504
184632378	184632400	4	-	27760321	HT29	viability after 19 days	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.7500405121115433	[430,336]	[339,803,1018]	7	hSpCas9	negative selection	5053505
184635293	184635315	4	-	27760321	HT29	viability after 19 days	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-0.16778911807889374	[99,77]	[15,238,11]	-1	hSpCas9	negative selection	5053506
184635339	184635361	4	-	27760321	HT29	viability after 19 days	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-0.4376856011146528	[27,21]	[0,5,52]	-4	hSpCas9	negative selection	5053507
184635354	184635376	4	-	27760321	HT29	viability after 19 days	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	1.8039294566075617	[4,3]	[0,0,48]	9	hSpCas9	negative selection	5053508
184632267	184632289	4	-	27760321	HT29	viability after 16 days	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	-0.016298602831647857	[290,226]	[275,189,394]	0	hSpCas9	negative selection	5136967
184632378	184632400	4	-	27760321	HT29	viability after 16 days	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.31729162160347446	[430,336]	[259,649,666]	3	hSpCas9	negative selection	5136968
184635293	184635315	4	-	27760321	HT29	viability after 16 days	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-0.8322919748237534	[99,77]	[16,58,87]	-6	hSpCas9	negative selection	5136969
184635339	184635361	4	-	27760321	HT29	viability after 16 days	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	-1.9686302758501504	[27,21]	[0,1,17]	-8	hSpCas9	negative selection	5136970
184635354	184635376	4	-	27760321	HT29	viability after 16 days	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	-0.9866831977360491	[4,3]	[5,0,0]	-7	hSpCas9	negative selection	5136971
184632267	184632289	4	-	27760321	HT29	viability after 13 days	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	-0.06609700581916866	[290,226]	[288,370,205]	-1	hSpCas9	negative selection	5220430
184632378	184632400	4	-	27760321	HT29	viability after 13 days	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.21630337985320328	[430,336]	[379,603,565]	2	hSpCas9	negative selection	5220431
184635293	184635315	4	-	27760321	HT29	viability after 13 days	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-1.459055914987859	[99,77]	[9,86,16]	-8	hSpCas9	negative selection	5220432
184635339	184635361	4	-	27760321	HT29	viability after 13 days	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	0.5825138735326085	[27,21]	[15,12,97]	7	hSpCas9	negative selection	5220433
184635354	184635376	4	-	27760321	HT29	viability after 13 days	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	1.6758893207552985	[4,3]	[30,0,17]	9	hSpCas9	negative selection	5220434
184632267	184632289	4	-	27760321	HT29	viability after 10 days	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	-0.05024200074832741	[290,226]	[467,345,127]	0	hSpCas9	negative selection	5303893
184632378	184632400	4	-	27760321	HT29	viability after 10 days	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	0.22778969794143558	[430,336]	[450,601,630]	3	hSpCas9	negative selection	5303894
184635293	184635315	4	-	27760321	HT29	viability after 10 days	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-0.849254432909182	[99,77]	[48,126,11]	-7	hSpCas9	negative selection	5303895
184635339	184635361	4	-	27760321	HT29	viability after 10 days	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	1.5478247882380414	[27,21]	[105,66,99]	9	hSpCas9	negative selection	5303896
184635354	184635376	4	-	27760321	HT29	viability after 10 days	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	0.16474990206745854	[4,3]	[5,7,4]	2	hSpCas9	negative selection	5303897
184632267	184632289	4	-	27760321	MOLM13	viability	TTGTGGAATTGATGCGTGATGG	CASP3	ENSG00000164305	0.9882932306076644	[309,290]	[227,428]	7	hSpCas9	negative selection	5387356
184632378	184632400	4	-	27760321	MOLM13	viability	AAGGAATGACATCTCGGTCTGG	CASP3	ENSG00000164305	1.0954046586364279	[492,430]	[767,374]	7	hSpCas9	negative selection	5387357
184635293	184635315	4	-	27760321	MOLM13	viability	AGAATTTTCATAAAAGCACTGG	CASP3	ENSG00000164305	-0.964018968910195	[118,99]	[3,54]	-5	hSpCas9	negative selection	5387358
184635339	184635361	4	-	27760321	MOLM13	viability	AAAATGGATTATCCTGAGATGG	CASP3	ENSG00000164305	2.1664695032151506	[39,27]	[183,0]	9	hSpCas9	negative selection	5387359
184635354	184635376	4	-	27760321	MOLM13	viability	CTGGACAACAGTTATAAAATGG	CASP3	ENSG00000164305	-2.6342471727415004	[17,4]	[0,0]	-8	hSpCas9	negative selection	5387360
184649344	184649367	4	+	27661255	K562	viability	GGGCTGACGGCCCGGAGCGAGGG	CASP3	ENSG00000164305	-0.14625039093990955	[370,317]	[291,212]	-5	dCas9-KRAB	negative selection	5468208
184649404	184649427	4	-	27661255	K562	viability	GGATGGGTGCTATTGTGAGGCGG	CASP3	ENSG00000164305	-0.05476356646332045	[856,845]	[742,579]	-2	dCas9-KRAB	negative selection	5468209
184632350	184632373	4	-	27260156	BXPC3	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.009138513301558682	[786]	[839,773,850,845]	0	hSpCas9	negative selection	5533469
184635326	184635349	4	+	27260156	BXPC3	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	-0.037439163304476386	[995]	[1037,901,1022,1103]	-1	hSpCas9	negative selection	5533470
184635372	184635395	4	-	27260156	BXPC3	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.4939963409943844	[409]	[603,680,534,581]	9	hSpCas9	negative selection	5533471
184632383	184632406	4	-	27260156	BXPC3	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.2925801110342602	[671]	[655,1001,928,864]	6	hSpCas9	negative selection	5597747
184631790	184631813	4	-	27260156	BXPC3	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.37733135879914864	[400]	[269,299,325,410]	-7	hSpCas9	negative selection	5597748
184631762	184631785	4	+	27260156	BXPC3	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.1312792915223251	[2502]	[2659,2650,2886,3341]	3	hSpCas9	negative selection	5597749
184632350	184632373	4	-	27260156	A673	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.06245086854969062	[786]	[928,846,822,1030]	-1	hSpCas9	negative selection	5654720
184635326	184635349	4	+	27260156	A673	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.12391041698355143	[995]	[1413,1270,1255,1281]	3	hSpCas9	negative selection	5654721
184635372	184635395	4	-	27260156	A673	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.34150424026044707	[409]	[839,454,566,663]	7	hSpCas9	negative selection	5654722
184632383	184632406	4	-	27260156	A673	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.31167784238817786	[671]	[1105,889,1001,1021]	7	hSpCas9	negative selection	5718998
184631790	184631813	4	-	27260156	A673	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.3781406082606236	[400]	[390,311,391,390]	-7	hSpCas9	negative selection	5718999
184631762	184631785	4	+	27260156	A673	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.054468228332757995	[2502]	[3687,2815,2842,3211]	1	hSpCas9	negative selection	5719000
184632350	184632373	4	-	27260156	A375	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.10351295084946299	[786]	[1190,1279,819,728]	1	hSpCas9	negative selection	5775971
184635326	184635349	4	+	27260156	A375	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.08659646891660056	[995]	[1331,1396,1507,777]	1	hSpCas9	negative selection	5775972
184635372	184635395	4	-	27260156	A375	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.4050642437251399	[409]	[723,793,544,508]	6	hSpCas9	negative selection	5775973
184632383	184632406	4	-	27260156	A375	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.1405043461690033	[671]	[736,1119,872,772]	2	hSpCas9	negative selection	5840249
184631790	184631813	4	-	27260156	A375	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.12829844091905035	[400]	[268,475,425,533]	-2	hSpCas9	negative selection	5840250
184631762	184631785	4	+	27260156	A375	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.40806789383244935	[2502]	[3832,4414,3367,3950]	6	hSpCas9	negative selection	5840251
184632350	184632373	4	-	27260156	COLO741	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.06757495703966687	[786]	[1252,987,942]	1	hSpCas9	negative selection	5897222
184635326	184635349	4	+	27260156	COLO741	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	-0.005787757210353739	[995]	[1136,1441,1213]	0	hSpCas9	negative selection	5897223
184635372	184635395	4	-	27260156	COLO741	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.15072807329120924	[409]	[667,493,587]	3	hSpCas9	negative selection	5897224
184632383	184632406	4	-	27260156	COLO741	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.6152887033507273	[671]	[1734,1266,999]	9	hSpCas9	negative selection	5961500
184631790	184631813	4	-	27260156	COLO741	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.9133408530783749	[400]	[388,286,157]	-9	hSpCas9	negative selection	5961501
184631762	184631785	4	+	27260156	COLO741	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.11838105959539869	[2502]	[3801,3490,3164]	2	hSpCas9	negative selection	5961502
184632350	184632373	4	-	27260156	CAL120	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.17016045065530838	[786]	[923,885,1461]	2	hSpCas9	negative selection	6018473
184635326	184635349	4	+	27260156	CAL120	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.3555758193681433	[995]	[1656,1607,1503]	5	hSpCas9	negative selection	6018474
184635372	184635395	4	-	27260156	CAL120	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.36027837348169545	[409]	[852,356,781]	5	hSpCas9	negative selection	6018475
184632383	184632406	4	-	27260156	CAL120	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.38471309228324413	[671]	[1118,677,1474]	6	hSpCas9	negative selection	6082751
184631790	184631813	4	-	27260156	CAL120	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.09503954639543777	[400]	[663,356,410]	-1	hSpCas9	negative selection	6082752
184631762	184631785	4	+	27260156	CAL120	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.313922118065908	[2502]	[4953,3302,3525]	5	hSpCas9	negative selection	6082753
184632350	184632373	4	-	27260156	CADOES1	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.13646224799800766	[786]	[533,755,735,636]	-2	hSpCas9	negative selection	6139724
184635326	184635349	4	+	27260156	CADOES1	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.09122767955886446	[995]	[1095,824,1053,970]	1	hSpCas9	negative selection	6139725
184635372	184635395	4	-	27260156	CADOES1	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.032244316851746196	[409]	[316,464,390,386]	0	hSpCas9	negative selection	6139726
184632383	184632406	4	-	27260156	CADOES1	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.3817115118651119	[671]	[1060,689,750,751]	6	hSpCas9	negative selection	6204002
184631790	184631813	4	-	27260156	CADOES1	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.033317460667469045	[400]	[271,483,394,304]	0	hSpCas9	negative selection	6204003
184631762	184631785	4	+	27260156	CADOES1	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.32647506364860224	[2502]	[3184,3283,2686,2504]	5	hSpCas9	negative selection	6204004
184632350	184632373	4	-	27260156	EWS502	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.22238383502132042	[786]	[826,913,815,1375]	4	hSpCas9	negative selection	6260975
184635326	184635349	4	+	27260156	EWS502	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.11162321980777823	[995]	[1013,1077,1060,1439]	2	hSpCas9	negative selection	6260976
184635372	184635395	4	-	27260156	EWS502	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.18694870756955115	[409]	[491,412,552,523]	3	hSpCas9	negative selection	6260977
184632383	184632406	4	-	27260156	EWS502	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.16499516186338148	[671]	[593,836,996,785]	3	hSpCas9	negative selection	6325253
184631790	184631813	4	-	27260156	EWS502	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.11376552778919036	[400]	[350,395,338,493]	-2	hSpCas9	negative selection	6325254
184631762	184631785	4	+	27260156	EWS502	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.1374901072944077	[2502]	[2672,2978,3005,3031]	2	hSpCas9	negative selection	6325255
184632350	184632373	4	-	27260156	EW8	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.09771789284071064	[786]	[612,644,443,707]	-2	hSpCas9	negative selection	6382226
184635326	184635349	4	+	27260156	EW8	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.14177514569448113	[995]	[914,910,712,1052]	2	hSpCas9	negative selection	6382227
184635372	184635395	4	-	27260156	EW8	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.3069661107520695	[409]	[613,419,308,339]	5	hSpCas9	negative selection	6382228
184632383	184632406	4	-	27260156	EW8	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.2850980918406253	[671]	[746,714,538,681]	5	hSpCas9	negative selection	6446504
184631790	184631813	4	-	27260156	EW8	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	0.02132476636133071	[400]	[528,231,221,374]	0	hSpCas9	negative selection	6446505
184631762	184631785	4	+	27260156	EW8	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.1622044346495919	[2502]	[2317,2355,2208,2205]	3	hSpCas9	negative selection	6446506
184632350	184632373	4	-	27260156	CORL105	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.06920235424759902	[786]	[894,872,1136,986]	1	hSpCas9	negative selection	6503477
184635326	184635349	4	+	27260156	CORL105	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.3004000951556203	[995]	[1457,1468,1382,1424]	5	hSpCas9	negative selection	6503478
184635372	184635395	4	-	27260156	CORL105	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.23990138385786924	[409]	[611,492,585,581]	4	hSpCas9	negative selection	6503479
184632383	184632406	4	-	27260156	CORL105	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.4741673390262925	[671]	[827,1068,1454,1066]	8	hSpCas9	negative selection	6567755
184631790	184631813	4	-	27260156	CORL105	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.03579227986192135	[400]	[560,305,645,354]	0	hSpCas9	negative selection	6567756
184631762	184631785	4	+	27260156	CORL105	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.3892971894365589	[2502]	[3630,3986,4513,3315]	7	hSpCas9	negative selection	6567757
184632350	184632373	4	-	27260156	HS294T	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.11680383235610392	[786]	[250,259,336,510]	1	hSpCas9	negative selection	6624728
184635326	184635349	4	+	27260156	HS294T	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.38367450212563226	[995]	[352,662,463,543]	5	hSpCas9	negative selection	6624729
184635372	184635395	4	-	27260156	HS294T	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.37475053461283026	[409]	[206,193,118,320]	5	hSpCas9	negative selection	6624730
184632383	184632406	4	-	27260156	HS294T	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	-0.12702907394740048	[671]	[190,155,259,373]	-2	hSpCas9	negative selection	6689006
184631790	184631813	4	-	27260156	HS294T	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.6101606392451839	[400]	[132,85,79,104]	-7	hSpCas9	negative selection	6689007
184631762	184631785	4	+	27260156	HS294T	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.16408729500377506	[2502]	[1005,998,916,1489]	2	hSpCas9	negative selection	6689008
184632350	184632373	4	-	27260156	HCC44	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.3314861837658144	[786]	[1345,886,1134,1157]	5	hSpCas9	negative selection	6745979
184635326	184635349	4	+	27260156	HCC44	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.5998973411837403	[995]	[1551,2124,1834,1265]	8	hSpCas9	negative selection	6745980
184635372	184635395	4	-	27260156	HCC44	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.4969782401655599	[409]	[502,303,1064,840]	7	hSpCas9	negative selection	6745981
184632383	184632406	4	-	27260156	HCC44	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.3580636999695693	[671]	[1012,843,1203,891]	6	hSpCas9	negative selection	6810257
184631790	184631813	4	-	27260156	HCC44	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.1485248438900963	[400]	[432,234,450,543]	-2	hSpCas9	negative selection	6810258
184631762	184631785	4	+	27260156	HCC44	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.15808482455820938	[2502]	[3567,2667,3334,3174]	2	hSpCas9	negative selection	6810259
184632350	184632373	4	-	27260156	G402	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.2492195352988953	[786]	[1260,797,1031,1451]	3	hSpCas9	negative selection	6867230
184635326	184635349	4	+	27260156	G402	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.20738229884864268	[995]	[1153,1689,1403,1342]	2	hSpCas9	negative selection	6867231
184635372	184635395	4	-	27260156	G402	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	-0.0021494209421263066	[409]	[637,780,419,207]	0	hSpCas9	negative selection	6867232
184632383	184632406	4	-	27260156	G402	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.3607452337882521	[671]	[1654,832,851,946]	4	hSpCas9	negative selection	6931508
184631790	184631813	4	-	27260156	G402	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	0.1993035584224124	[400]	[984,528,372,423]	2	hSpCas9	negative selection	6931509
184631762	184631785	4	+	27260156	G402	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.46635778376240333	[2502]	[4260,4418,4999,3247]	6	hSpCas9	negative selection	6931510
184632350	184632373	4	-	27260156	L33	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.0679870483200492	[786]	[683,329,491,1028]	1	hSpCas9	negative selection	6988481
184635326	184635349	4	+	27260156	L33	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.22625201841334608	[995]	[1204,399,703,1355]	5	hSpCas9	negative selection	6988482
184635372	184635395	4	-	27260156	L33	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.02170029514245092	[409]	[399,229,221,350]	0	hSpCas9	negative selection	6988483
184632383	184632406	4	-	27260156	L33	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.18524870985997555	[671]	[648,384,425,791]	4	hSpCas9	negative selection	7052759
184631790	184631813	4	-	27260156	L33	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.24313159620701297	[400]	[366,122,246,294]	-5	hSpCas9	negative selection	7052760
184631762	184631785	4	+	27260156	L33	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	-0.009815142300680257	[2502]	[2254,1102,1702,2295]	0	hSpCas9	negative selection	7052761
184632350	184632373	4	-	27260156	K562	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.13727222088702218	[786]	[1374,649,680,444]	1	hSpCas9	negative selection	7109732
184635326	184635349	4	+	27260156	K562	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.584363098816737	[995]	[1175,1527,888,1660]	7	hSpCas9	negative selection	7109733
184635372	184635395	4	-	27260156	K562	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.06642147768612267	[409]	[326,385,299,491]	0	hSpCas9	negative selection	7109734
184632383	184632406	4	-	27260156	K562	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.5343008190947487	[671]	[1069,841,957,624]	6	hSpCas9	negative selection	7174010
184631790	184631813	4	-	27260156	K562	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.0349113063458798	[400]	[368,237,514,270]	0	hSpCas9	negative selection	7174011
184631762	184631785	4	+	27260156	K562	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.44142255061649305	[2502]	[3298,2482,3310,2960]	5	hSpCas9	negative selection	7174012
184632350	184632373	4	-	27260156	HT29	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.17363562498246854	[786]	[1389,910,1190,853]	3	hSpCas9	negative selection	7230983
184635326	184635349	4	+	27260156	HT29	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.23785327094705	[995]	[1371,1730,1367,1270]	4	hSpCas9	negative selection	7230984
184635372	184635395	4	-	27260156	HT29	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.19238380257141488	[409]	[617,615,526,525]	4	hSpCas9	negative selection	7230985
184632383	184632406	4	-	27260156	HT29	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.33671445208010964	[671]	[1045,1274,967,871]	6	hSpCas9	negative selection	7295261
184631790	184631813	4	-	27260156	HT29	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.05327125343536243	[400]	[419,448,610,398]	-1	hSpCas9	negative selection	7295262
184631762	184631785	4	+	27260156	HT29	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.25272719614004924	[2502]	[4368,3952,3440,2888]	5	hSpCas9	negative selection	7295263
184632350	184632373	4	-	27260156	MHHES1	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.11283381351638244	[786]	[1094,947,797,532]	-2	hSpCas9	negative selection	7352234
184635326	184635349	4	+	27260156	MHHES1	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.33885959595120596	[995]	[1429,1731,1512,1080]	6	hSpCas9	negative selection	7352235
184635372	184635395	4	-	27260156	MHHES1	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.19041748590025948	[409]	[652,451,593,427]	3	hSpCas9	negative selection	7352236
184632383	184632406	4	-	27260156	MHHES1	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.3851327016602504	[671]	[991,1270,848,873]	7	hSpCas9	negative selection	7416512
184631790	184631813	4	-	27260156	MHHES1	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.4257485457438243	[400]	[456,388,325,213]	-7	hSpCas9	negative selection	7416513
184631762	184631785	4	+	27260156	MHHES1	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.3718266105712571	[2502]	[3628,4144,4010,2939]	6	hSpCas9	negative selection	7416514
184632350	184632373	4	-	27260156	MEWO	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.1496135369911884	[786]	[637,690,656]	-3	hSpCas9	negative selection	7473485
184635326	184635349	4	+	27260156	MEWO	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.061097646433553976	[995]	[1102,874,963]	1	hSpCas9	negative selection	7473486
184635372	184635395	4	-	27260156	MEWO	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.02616237902478863	[409]	[406,367,399]	0	hSpCas9	negative selection	7473487
184632383	184632406	4	-	27260156	MEWO	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.3001700205154253	[671]	[908,832,605]	6	hSpCas9	negative selection	7537763
184631790	184631813	4	-	27260156	MEWO	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.48249000438503714	[400]	[299,184,326]	-8	hSpCas9	negative selection	7537764
184631762	184631785	4	+	27260156	MEWO	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	-0.1273143321854251	[2502]	[2651,1673,2205]	-3	hSpCas9	negative selection	7537765
184632350	184632373	4	-	27260156	LNCAPCLONEFGC	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.10628020150700557	[786]	[832,605,891,765]	1	hSpCas9	negative selection	7594736
184635326	184635349	4	+	27260156	LNCAPCLONEFGC	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.044798532696675775	[995]	[923,794,1063,967]	0	hSpCas9	negative selection	7594737
184635372	184635395	4	-	27260156	LNCAPCLONEFGC	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.583704562848997	[409]	[530,499,668,546]	8	hSpCas9	negative selection	7594738
184632383	184632406	4	-	27260156	LNCAPCLONEFGC	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.24067880917150186	[671]	[593,868,718,686]	4	hSpCas9	negative selection	7659014
184631790	184631813	4	-	27260156	LNCAPCLONEFGC	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.13101771618494223	[400]	[302,376,289,347]	-2	hSpCas9	negative selection	7659015
184631762	184631785	4	+	27260156	LNCAPCLONEFGC	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.40708743156558524	[2502]	[3066,2917,3223,2851]	6	hSpCas9	negative selection	7659016
184632350	184632373	4	-	27260156	PANC0327	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.10153498334983357	[786]	[650,549,936,879]	1	hSpCas9	negative selection	7715987
184635326	184635349	4	+	27260156	PANC0327	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.23756315681804763	[995]	[1069,820,1078,1232]	3	hSpCas9	negative selection	7715988
184635372	184635395	4	-	27260156	PANC0327	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.13255380507421555	[409]	[372,565,259,373]	2	hSpCas9	negative selection	7715989
184632383	184632406	4	-	27260156	PANC0327	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.45109651689935215	[671]	[1259,861,475,695]	6	hSpCas9	negative selection	7780265
184631790	184631813	4	-	27260156	PANC0327	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.152529160038552	[400]	[547,229,233,299]	-2	hSpCas9	negative selection	7780266
184631762	184631785	4	+	27260156	PANC0327	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.317526361914807	[2502]	[2964,2708,2581,2849]	5	hSpCas9	negative selection	7780267
184632350	184632373	4	-	27260156	NCIH2009	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.33497103293463415	[786]	[1488,1200,1491]	4	hSpCas9	negative selection	7837238
184635326	184635349	4	+	27260156	NCIH2009	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.4819171614952331	[995]	[2054,1509,2291]	6	hSpCas9	negative selection	7837239
184635372	184635395	4	-	27260156	NCIH2009	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.3977243320723445	[409]	[800,692,778]	5	hSpCas9	negative selection	7837240
184632383	184632406	4	-	27260156	NCIH2009	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.6354315643089701	[671]	[2270,1157,1109]	8	hSpCas9	negative selection	7901516
184631790	184631813	4	-	27260156	NCIH2009	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	0.22884737682216827	[400]	[868,467,676]	3	hSpCas9	negative selection	7901517
184631762	184631785	4	+	27260156	NCIH2009	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.26704755074967723	[2502]	[5050,3657,4084]	3	hSpCas9	negative selection	7901518
184632350	184632373	4	-	27260156	NCIH1373	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.4448932146840049	[786]	[978,1782,1047,228]	4	hSpCas9	negative selection	7958489
184635326	184635349	4	+	27260156	NCIH1373	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.3163981137079521	[995]	[2225,975,1324,312]	3	hSpCas9	negative selection	7958490
184635372	184635395	4	-	27260156	NCIH1373	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.6016128526849348	[409]	[894,992,545,86]	6	hSpCas9	negative selection	7958491
184632383	184632406	4	-	27260156	NCIH1373	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.12979348125768198	[671]	[1280,804,576,183]	1	hSpCas9	negative selection	8022767
184631790	184631813	4	-	27260156	NCIH1373	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	0.17023703875958812	[400]	[501,587,426,129]	1	hSpCas9	negative selection	8022768
184631762	184631785	4	+	27260156	NCIH1373	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.611490693525162	[2502]	[4435,4681,3840,1088]	6	hSpCas9	negative selection	8022769
184632350	184632373	4	-	27260156	PATU8902	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.29468247645315604	[786]	[1277,1634,1253,1208]	3	hSpCas9	negative selection	8079740
184635326	184635349	4	+	27260156	PATU8902	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.7071420965854209	[995]	[1881,2652,1628,3153]	7	hSpCas9	negative selection	8079741
184635372	184635395	4	-	27260156	PATU8902	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.5689596154496731	[409]	[949,940,511,1093]	6	hSpCas9	negative selection	8079742
184632383	184632406	4	-	27260156	PATU8902	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.647775699468625	[671]	[1171,2009,1248,1486]	6	hSpCas9	negative selection	8144018
184631790	184631813	4	-	27260156	PATU8902	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-1.1348358015319	[400]	[192,209,388,179]	-7	hSpCas9	negative selection	8144019
184631762	184631785	4	+	27260156	PATU8902	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.6738962917740765	[2502]	[5127,5789,4952,6620]	7	hSpCas9	negative selection	8144020
184632350	184632373	4	-	27260156	PANC1	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.18602803057541295	[786]	[731,777,741,806]	3	hSpCas9	negative selection	8200991
184635326	184635349	4	+	27260156	PANC1	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.268571715044986	[995]	[831,1233,1159,940]	4	hSpCas9	negative selection	8200992
184635372	184635395	4	-	27260156	PANC1	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.2725556461621803	[409]	[371,684,373,332]	4	hSpCas9	negative selection	8200993
184632383	184632406	4	-	27260156	PANC1	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.3732971667089334	[671]	[796,1024,643,592]	6	hSpCas9	negative selection	8265269
184631790	184631813	4	-	27260156	PANC1	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	0.02891368076873252	[400]	[239,596,323,299]	0	hSpCas9	negative selection	8265270
184631762	184631785	4	+	27260156	PANC1	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.2602565368316294	[2502]	[2472,3668,2517,1930]	4	hSpCas9	negative selection	8265271
184632350	184632373	4	-	27260156	PANC0813	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.29145699649775414	[786]	[1412,1103,1111,931]	5	hSpCas9	negative selection	8322242
184635326	184635349	4	+	27260156	PANC0813	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.27860529088609787	[995]	[1719,1380,1163,1434]	4	hSpCas9	negative selection	8322243
184635372	184635395	4	-	27260156	PANC0813	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.021331429189272666	[409]	[491,402,621,440]	0	hSpCas9	negative selection	8322244
184632383	184632406	4	-	27260156	PANC0813	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.37398898141603776	[671]	[1256,956,1215,700]	6	hSpCas9	negative selection	8386520
184631790	184631813	4	-	27260156	PANC0813	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	0.4566194117214126	[400]	[882,464,536,716]	7	hSpCas9	negative selection	8386521
184631762	184631785	4	+	27260156	PANC0813	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.12436899186747308	[2502]	[3396,3309,2964,3160]	2	hSpCas9	negative selection	8386522
184632350	184632373	4	-	27260156	RDES	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.19573007834387024	[786]	[747,995,1287,1182]	3	hSpCas9	negative selection	8443493
184635326	184635349	4	+	27260156	RDES	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.2955190162882415	[995]	[1098,1459,1256,1894]	5	hSpCas9	negative selection	8443494
184635372	184635395	4	-	27260156	RDES	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.5520295963980884	[409]	[589,705,632,857]	8	hSpCas9	negative selection	8443495
184632383	184632406	4	-	27260156	RDES	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.23322837887944337	[671]	[632,864,1140,1065]	4	hSpCas9	negative selection	8507771
184631790	184631813	4	-	27260156	RDES	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.0037089148518235915	[400]	[354,415,604,486]	0	hSpCas9	negative selection	8507772
184631762	184631785	4	+	27260156	RDES	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.36623318463666843	[2502]	[2860,3611,3914,4694]	6	hSpCas9	negative selection	8507773
184632350	184632373	4	-	27260156	PC3	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.04864825435505127	[786]	[498,743,1187,1033]	1	hSpCas9	negative selection	8564744
184635326	184635349	4	+	27260156	PC3	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.20256130793883198	[995]	[851,1191,1809,960]	4	hSpCas9	negative selection	8564745
184635372	184635395	4	-	27260156	PC3	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.10456810174349845	[409]	[255,277,843,594]	2	hSpCas9	negative selection	8564746
184632383	184632406	4	-	27260156	PC3	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.4539990404089558	[671]	[547,1084,1515,814]	8	hSpCas9	negative selection	8629022
184631790	184631813	4	-	27260156	PC3	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.6981135859398591	[400]	[94,242,566,256]	-9	hSpCas9	negative selection	8629023
184631762	184631785	4	+	27260156	PC3	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.012499449448200028	[2502]	[1644,2397,3951,2775]	0	hSpCas9	negative selection	8629024
184632350	184632373	4	-	27260156	PATU8988T	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.09008925845667692	[786]	[481,1070,636,700]	-1	hSpCas9	negative selection	8685995
184635326	184635349	4	+	27260156	PATU8988T	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.027165838873638437	[995]	[794,1069,972,1102]	0	hSpCas9	negative selection	8685996
184635372	184635395	4	-	27260156	PATU8988T	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	-0.012736991429987715	[409]	[345,467,332,434]	0	hSpCas9	negative selection	8685997
184632383	184632406	4	-	27260156	PATU8988T	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.19414342465858891	[671]	[571,590,821,990]	3	hSpCas9	negative selection	8750273
184631790	184631813	4	-	27260156	PATU8988T	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	0.3131295054530924	[400]	[741,500,296,381]	5	hSpCas9	negative selection	8750274
184631762	184631785	4	+	27260156	PATU8988T	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.045871408474114084	[2502]	[2287,2363,2710,2617]	0	hSpCas9	negative selection	8750275
184632350	184632373	4	-	27260156	T47D	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.08512635915571987	[786]	[813,854,955,829]	-2	hSpCas9	negative selection	8807246
184635326	184635349	4	+	27260156	T47D	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.3388051578472755	[995]	[1534,1356,1528,1456]	7	hSpCas9	negative selection	8807247
184635372	184635395	4	-	27260156	T47D	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.318050028238379	[409]	[651,537,636,557]	6	hSpCas9	negative selection	8807248
184632383	184632406	4	-	27260156	T47D	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.30136170633640225	[671]	[919,983,1035,913]	6	hSpCas9	negative selection	8871524
184631790	184631813	4	-	27260156	T47D	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.1837930324896735	[400]	[456,372,357,462]	-4	hSpCas9	negative selection	8871525
184631762	184631785	4	+	27260156	T47D	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.20050944094747258	[2502]	[3246,3392,3462,3290]	4	hSpCas9	negative selection	8871526
184632350	184632373	4	-	27260156	SU8686	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.11279673198299212	[786]	[785,816,934,842]	2	hSpCas9	negative selection	8928497
184635326	184635349	4	+	27260156	SU8686	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.35450437094714626	[995]	[985,1199,1256,1709]	6	hSpCas9	negative selection	8928498
184635372	184635395	4	-	27260156	SU8686	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.04732375190980989	[409]	[501,351,376,448]	0	hSpCas9	negative selection	8928499
184632383	184632406	4	-	27260156	SU8686	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.1410009710507487	[671]	[703,652,769,837]	2	hSpCas9	negative selection	8992775
184631790	184631813	4	-	27260156	SU8686	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.18804806916275196	[400]	[292,345,319,457]	-3	hSpCas9	negative selection	8992776
184631762	184631785	4	+	27260156	SU8686	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.2792126142350537	[2502]	[2762,2396,3427,3660]	5	hSpCas9	negative selection	8992777
184632350	184632373	4	-	27260156	SKES1	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.13641525628481932	[786]	[722,1096,899,744]	3	hSpCas9	negative selection	9049748
184635326	184635349	4	+	27260156	SKES1	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.12829229921708896	[995]	[1262,989,983,1106]	3	hSpCas9	negative selection	9049749
184635372	184635395	4	-	27260156	SKES1	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.1872137773511056	[409]	[298,672,535,362]	4	hSpCas9	negative selection	9049750
184632383	184632406	4	-	27260156	SKES1	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.3239973881050384	[671]	[782,860,919,783]	6	hSpCas9	negative selection	9114026
184631790	184631813	4	-	27260156	SKES1	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.13528062338300767	[400]	[416,412,310,329]	-3	hSpCas9	negative selection	9114027
184631762	184631785	4	+	27260156	SKES1	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.14600184738227595	[2502]	[3100,3175,2490,2397]	3	hSpCas9	negative selection	9114028
184632350	184632373	4	-	27260156	TOV112D	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.10770777776704954	[786]	[892,614,988,844]	2	hSpCas9	negative selection	9170999
184635326	184635349	4	+	27260156	TOV112D	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.29079164976850036	[995]	[1045,1557,1172,1171]	5	hSpCas9	negative selection	9171000
184635372	184635395	4	-	27260156	TOV112D	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.49710509153006543	[409]	[515,693,691,441]	8	hSpCas9	negative selection	9171001
184632383	184632406	4	-	27260156	TOV112D	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.1539672309576765	[671]	[828,697,662,796]	3	hSpCas9	negative selection	9235277
184631790	184631813	4	-	27260156	TOV112D	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.3939414244289789	[400]	[301,252,208,440]	-7	hSpCas9	negative selection	9235278
184631762	184631785	4	+	27260156	TOV112D	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.19565131506367273	[2502]	[2726,3563,2562,2785]	4	hSpCas9	negative selection	9235279
184632350	184632373	4	-	27260156	TC71	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.039803521241624895	[786]	[802,857,947,857]	1	hSpCas9	negative selection	9292250
184635326	184635349	4	+	27260156	TC71	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.12308950568251387	[995]	[1282,1059,1190,1109]	3	hSpCas9	negative selection	9292251
184635372	184635395	4	-	27260156	TC71	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.06577584216644194	[409]	[434,464,378,570]	1	hSpCas9	negative selection	9292252
184632383	184632406	4	-	27260156	TC71	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.268611032055984	[671]	[780,936,948,798]	6	hSpCas9	negative selection	9356528
184631790	184631813	4	-	27260156	TC71	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.5982962786509882	[400]	[271,219,352,288]	-9	hSpCas9	negative selection	9356529
184631762	184631785	4	+	27260156	TC71	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.05466955385700789	[2502]	[2742,2493,2732,3204]	1	hSpCas9	negative selection	9356530
184632350	184632373	4	-	27260156	TC32	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.03002096674492427	[786]	[746,560,1001,783]	0	hSpCas9	negative selection	9413501
184635326	184635349	4	+	27260156	TC32	viability	ATTATACATAAACCCATCTCAGG	CASP3	ENSG00000164305	0.08260945305371625	[995]	[928,834,1237,1011]	1	hSpCas9	negative selection	9413502
184635372	184635395	4	-	27260156	TC32	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	-0.11332457087807576	[409]	[392,106,601,441]	-2	hSpCas9	negative selection	9413503
184632383	184632406	4	-	27260156	TC32	viability	TGTTCCAAGGAATGACATCTCGG	CASP3	ENSG00000164305	0.04386749313092819	[671]	[607,431,878,782]	0	hSpCas9	negative selection	9477779
184631790	184631813	4	-	27260156	TC32	viability	GATCGTTGTAGAAGTCTAACTGG	CASP3	ENSG00000164305	-0.5399718056890455	[400]	[233,177,473,203]	-8	hSpCas9	negative selection	9477780
184631762	184631785	4	+	27260156	TC32	viability	TACCTGAATAATGAAAAGTTTGG	CASP3	ENSG00000164305	0.2447809857697214	[2502]	[2367,2390,3507,3053]	4	hSpCas9	negative selection	9477781
184629373	184629396	4	+	27869803	HPAFII	viability after 27 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.7620061650391001	[300]	[419,141,NaN]	6	hSpCas9	negative selection	9587711
184629374	184629397	4	+	27869803	HPAFII	viability after 27 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.8220371763553549	[294]	[102,74,NaN]	-5	hSpCas9	negative selection	9587712
184629379	184629402	4	-	27869803	HPAFII	viability after 27 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.8434028420899489	[161]	[208,105,NaN]	6	hSpCas9	negative selection	9587713
184629436	184629459	4	+	27869803	HPAFII	viability after 27 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.6949171529405019	[399]	[100,153,NaN]	-5	hSpCas9	negative selection	9587714
184631057	184631080	4	+	27869803	HPAFII	viability after 27 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	1.4715474122002714	[52]	[121,39,NaN]	9	hSpCas9	negative selection	9587715
184629373	184629396	4	+	27869803	HPAFII	viability after 15 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.6328778319370861	[300]	[611,432,NaN]	7	hSpCas9	negative selection	9670160
184629374	184629397	4	+	27869803	HPAFII	viability after 15 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.19819354803299905	[294]	[448,168,NaN]	-2	hSpCas9	negative selection	9670161
184629379	184629402	4	-	27869803	HPAFII	viability after 15 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	1.0529201206989351	[161]	[597,213,NaN]	9	hSpCas9	negative selection	9670162
184629436	184629459	4	+	27869803	HPAFII	viability after 15 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.6473445740635366	[399]	[271,275,NaN]	-6	hSpCas9	negative selection	9670163
184631057	184631080	4	+	27869803	HPAFII	viability after 15 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	1.3070418472322056	[52]	[209,97,NaN]	9	hSpCas9	negative selection	9670164
184629373	184629396	4	+	27869803	ASPC1	viability after 36 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.8584405265146285	[768]	[621,450,414]	8	hSpCas9	negative selection	9752609
184629374	184629397	4	+	27869803	ASPC1	viability after 36 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.0006454501012451708	[1039]	[348,640,147]	0	hSpCas9	negative selection	9752610
184629379	184629402	4	-	27869803	ASPC1	viability after 36 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	1.4274341189739195	[437]	[456,313,451]	9	hSpCas9	negative selection	9752611
184629436	184629459	4	+	27869803	ASPC1	viability after 36 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.21262995298412612	[961]	[302,424,416]	2	hSpCas9	negative selection	9752612
184631057	184631080	4	+	27869803	ASPC1	viability after 36 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-0.020956164152499124	[261]	[117,129,37]	0	hSpCas9	negative selection	9752613
184629373	184629396	4	+	27869803	PATU8988S	viability after 35 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	0.4121004178212276	[712]	[207,556,NaN]	4	hSpCas9	negative selection	9835058
184629374	184629397	4	+	27869803	PATU8988S	viability after 35 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	0.014772361994281669	[916]	[426,318,NaN]	0	hSpCas9	negative selection	9835059
184629379	184629402	4	-	27869803	PATU8988S	viability after 35 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.07209307143253647	[488]	[222,190,NaN]	0	hSpCas9	negative selection	9835060
184629436	184629459	4	+	27869803	PATU8988S	viability after 35 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.4952090781667666	[876]	[655,338,NaN]	5	hSpCas9	negative selection	9835061
184631057	184631080	4	+	27869803	PATU8988S	viability after 35 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	0.15662340701002786	[144]	[106,22,NaN]	1	hSpCas9	negative selection	9835062
184629373	184629396	4	+	27869803	PATU8988S	viability after 31 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	-0.10942708633963244	[712]	[153,402,NaN]	-1	hSpCas9	negative selection	9917507
184629374	184629397	4	+	27869803	PATU8988S	viability after 31 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.057539591675935586	[916]	[309,403,NaN]	0	hSpCas9	negative selection	9917508
184629379	184629402	4	-	27869803	PATU8988S	viability after 31 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.039525029435021286	[488]	[206,191,NaN]	0	hSpCas9	negative selection	9917509
184629436	184629459	4	+	27869803	PATU8988S	viability after 31 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	0.03246028554792557	[876]	[431,262,NaN]	0	hSpCas9	negative selection	9917510
184631057	184631080	4	+	27869803	PATU8988S	viability after 31 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	-0.6469978365663658	[144]	[50,18,NaN]	-6	hSpCas9	negative selection	9917511
184629373	184629396	4	+	27869803	HPAFII	viability after 35 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	1.2051925779048365	[300]	[443,246,NaN]	7	hSpCas9	negative selection	9999956
184629374	184629397	4	+	27869803	HPAFII	viability after 35 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.9186296632109507	[294]	[86,69,NaN]	-5	hSpCas9	negative selection	9999957
184629379	184629402	4	-	27869803	HPAFII	viability after 35 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	0.8832466496158455	[161]	[226,65,NaN]	6	hSpCas9	negative selection	9999958
184629436	184629459	4	+	27869803	HPAFII	viability after 35 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.4167317106406878	[399]	[130,174,NaN]	-3	hSpCas9	negative selection	9999959
184631057	184631080	4	+	27869803	HPAFII	viability after 35 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	1.189478757439099	[52]	[95,21,NaN]	7	hSpCas9	negative selection	9999960
184629373	184629396	4	+	27869803	HPAFII	viability after 31 days	TTGCCACCTTTCGGTTAACCCGG	CASP3	ENSG00000164305	1.1015887078178526	[300]	[395,325,NaN]	7	hSpCas9	negative selection	10082405
184629374	184629397	4	+	27869803	HPAFII	viability after 31 days	TGCCACCTTTCGGTTAACCCGGG	CASP3	ENSG00000164305	-0.8480861000412341	[294]	[68,116,NaN]	-5	hSpCas9	negative selection	10082406
184629379	184629402	4	-	27869803	HPAFII	viability after 31 days	TCTTACCCGGGTTAACCGAAAGG	CASP3	ENSG00000164305	1.1165665538921365	[161]	[255,132,NaN]	8	hSpCas9	negative selection	10082407
184629436	184629459	4	+	27869803	HPAFII	viability after 31 days	TCAGCATGGCACAAAGCGACTGG	CASP3	ENSG00000164305	-0.8051812536800682	[399]	[138,116,NaN]	-5	hSpCas9	negative selection	10082408
184631057	184631080	4	+	27869803	HPAFII	viability after 31 days	TACAAGAAGTCGGCCTCCACTGG	CASP3	ENSG00000164305	1.310720361919514	[52]	[135,5,NaN]	8	hSpCas9	negative selection	10082409
184631073	184631096	4	-	28162770	P31FUJ	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.4615715130273593	[109]	[177]	5	hSpCas9	negative selection	10126195
184631129	184631152	4	-	28162770	P31FUJ	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.09927384584906673	[594]	[748]	1	hSpCas9	negative selection	10126196
184631883	184631906	4	-	28162770	P31FUJ	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.8554738045648946	[625]	[1330]	8	hSpCas9	negative selection	10126197
184631147	184631170	4	-	28162770	P31FUJ	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.28459701249414304	[152]	[218]	3	hSpCas9	negative selection	10126198
184631026	184631049	4	+	28162770	P31FUJ	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.46283226322828674	[346]	[561]	5	hSpCas9	negative selection	10126199
184631111	184631134	4	-	28162770	P31FUJ	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.8078397800829673	[279]	[575]	8	hSpCas9	negative selection	10126200
184631047	184631070	4	+	28162770	P31FUJ	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.3557715498591567	[398]	[599]	4	hSpCas9	negative selection	10126201
184635372	184635395	4	-	28162770	P31FUJ	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.6510350960359574	[613]	[1132]	7	hSpCas9	negative selection	10126202
184632350	184632373	4	-	28162770	P31FUJ	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.16154352124455684	[394]	[414]	-1	hSpCas9	negative selection	10126203
184632334	184632357	4	+	28162770	P31FUJ	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.43634507764775843	[526]	[837]	5	hSpCas9	negative selection	10126204
184631073	184631096	4	-	28162770	TF1	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10295561
184631129	184631152	4	-	28162770	TF1	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	NaN	[NaN]	[479]	1	hSpCas9	negative selection	10295562
184631883	184631906	4	-	28162770	TF1	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	NaN	[NaN]	[651]	1	hSpCas9	negative selection	10295563
184631147	184631170	4	-	28162770	TF1	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10295564
184631026	184631049	4	+	28162770	TF1	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	NaN	[NaN]	[363]	1	hSpCas9	negative selection	10295565
184631111	184631134	4	-	28162770	TF1	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	NaN	[NaN]	[443]	1	hSpCas9	negative selection	10295566
184631047	184631070	4	+	28162770	TF1	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	NaN	[NaN]	[365]	1	hSpCas9	negative selection	10295567
184635372	184635395	4	-	28162770	TF1	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	NaN	[NaN]	[1010]	1	hSpCas9	negative selection	10295568
184632350	184632373	4	-	28162770	TF1	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	NaN	[NaN]	[404]	1	hSpCas9	negative selection	10295569
184632334	184632357	4	+	28162770	TF1	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	NaN	[NaN]	[687]	1	hSpCas9	negative selection	10295570
184631073	184631096	4	-	28162770	SKM1	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	-0.47407839460169854	[32]	[41]	-4	hSpCas9	negative selection	10464927
184631129	184631152	4	-	28162770	SKM1	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.3646990161711334	[151]	[345]	3	hSpCas9	negative selection	10464928
184631883	184631906	4	-	28162770	SKM1	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	-0.2392776694968488	[214]	[321]	-2	hSpCas9	negative selection	10464929
184631147	184631170	4	-	28162770	SKM1	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.23786975795539309	[58]	[122]	2	hSpCas9	negative selection	10464930
184631026	184631049	4	+	28162770	SKM1	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.2517079881610036	[123]	[260]	2	hSpCas9	negative selection	10464931
184631111	184631134	4	-	28162770	SKM1	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.26779497232864014	[108]	[231]	2	hSpCas9	negative selection	10464932
184631047	184631070	4	+	28162770	SKM1	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.09782795329401106	[110]	[209]	0	hSpCas9	negative selection	10464933
184635372	184635395	4	-	28162770	SKM1	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.664107415772865	[150]	[422]	6	hSpCas9	negative selection	10464934
184632350	184632373	4	-	28162770	SKM1	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.1992669187316456	[100]	[204]	2	hSpCas9	negative selection	10464935
184632334	184632357	4	+	28162770	SKM1	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.1779983019779945	[104]	[209]	1	hSpCas9	negative selection	10464936
184631073	184631096	4	-	28162770	SKM1	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	-0.47407839460169854	[32]	[41]	-4	hSpCas9	negative selection	10634293
184631129	184631152	4	-	28162770	SKM1	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.3646990161711334	[151]	[345]	3	hSpCas9	negative selection	10634294
184631883	184631906	4	-	28162770	SKM1	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	-0.2392776694968488	[214]	[321]	-2	hSpCas9	negative selection	10634295
184631147	184631170	4	-	28162770	SKM1	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.23786975795539309	[58]	[122]	2	hSpCas9	negative selection	10634296
184631026	184631049	4	+	28162770	SKM1	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.2517079881610036	[123]	[260]	2	hSpCas9	negative selection	10634297
184631111	184631134	4	-	28162770	SKM1	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.26779497232864014	[108]	[231]	2	hSpCas9	negative selection	10634298
184631047	184631070	4	+	28162770	SKM1	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.09782795329401106	[110]	[209]	0	hSpCas9	negative selection	10634299
184635372	184635395	4	-	28162770	SKM1	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.664107415772865	[150]	[422]	6	hSpCas9	negative selection	10634300
184632350	184632373	4	-	28162770	SKM1	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.1992669187316456	[100]	[204]	2	hSpCas9	negative selection	10634301
184632334	184632357	4	+	28162770	SKM1	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.1779983019779945	[104]	[209]	1	hSpCas9	negative selection	10634302
184631073	184631096	4	-	28162770	PL21	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	-0.15495534433324176	[109]	[42]	-1	hSpCas9	negative selection	10803659
184631129	184631152	4	-	28162770	PL21	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.13976699650983826	[487]	[233]	1	hSpCas9	negative selection	10803660
184631883	184631906	4	-	28162770	PL21	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.6345424386350949	[702]	[474]	5	hSpCas9	negative selection	10803661
184631147	184631170	4	-	28162770	PL21	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.5856903492677834	[172]	[112]	5	hSpCas9	negative selection	10803662
184631026	184631049	4	+	28162770	PL21	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.28836679750105554	[332]	[176]	2	hSpCas9	negative selection	10803663
184631111	184631134	4	-	28162770	PL21	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	-0.3335423812881428	[303]	[104]	-2	hSpCas9	negative selection	10803664
184631047	184631070	4	+	28162770	PL21	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.4933886333701215	[314]	[192]	4	hSpCas9	negative selection	10803665
184635372	184635395	4	-	28162770	PL21	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	1.5478840011808197	[575]	[732]	9	hSpCas9	negative selection	10803666
184632350	184632373	4	-	28162770	PL21	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.36324041681770064	[258]	[144]	3	hSpCas9	negative selection	10803667
184632334	184632357	4	+	28162770	PL21	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.9210669985637547	[397]	[327]	7	hSpCas9	negative selection	10803668
184631073	184631096	4	-	28162770	P31FUJ	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.4615715130273593	[109]	[177]	5	hSpCas9	negative selection	10973025
184631129	184631152	4	-	28162770	P31FUJ	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.09927384584906673	[594]	[748]	1	hSpCas9	negative selection	10973026
184631883	184631906	4	-	28162770	P31FUJ	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.8554738045648946	[625]	[1330]	8	hSpCas9	negative selection	10973027
184631147	184631170	4	-	28162770	P31FUJ	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.28459701249414304	[152]	[218]	3	hSpCas9	negative selection	10973028
184631026	184631049	4	+	28162770	P31FUJ	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.46283226322828674	[346]	[561]	5	hSpCas9	negative selection	10973029
184631111	184631134	4	-	28162770	P31FUJ	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.8078397800829673	[279]	[575]	8	hSpCas9	negative selection	10973030
184631047	184631070	4	+	28162770	P31FUJ	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.3557715498591567	[398]	[599]	4	hSpCas9	negative selection	10973031
184635372	184635395	4	-	28162770	P31FUJ	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.6510350960359574	[613]	[1132]	7	hSpCas9	negative selection	10973032
184632350	184632373	4	-	28162770	P31FUJ	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.16154352124455684	[394]	[414]	-1	hSpCas9	negative selection	10973033
184632334	184632357	4	+	28162770	P31FUJ	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.43634507764775843	[526]	[837]	5	hSpCas9	negative selection	10973034
184631073	184631096	4	-	28162770	OCIAML5	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	-0.791525028928946	[69]	[72]	-5	hSpCas9	negative selection	11142391
184631129	184631152	4	-	28162770	OCIAML5	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.15703563624325545	[394]	[794]	1	hSpCas9	negative selection	11142392
184631883	184631906	4	-	28162770	OCIAML5	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.8240076025088563	[270]	[865]	7	hSpCas9	negative selection	11142393
184631147	184631170	4	-	28162770	OCIAML5	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.48897034697106995	[89]	[227]	4	hSpCas9	negative selection	11142394
184631026	184631049	4	+	28162770	OCIAML5	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.777872838575543	[199]	[618]	6	hSpCas9	negative selection	11142395
184631111	184631134	4	-	28162770	OCIAML5	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.826610364679353	[148]	[476]	7	hSpCas9	negative selection	11142396
184631047	184631070	4	+	28162770	OCIAML5	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	-0.31903186218670165	[263]	[381]	-2	hSpCas9	negative selection	11142397
184635372	184635395	4	-	28162770	OCIAML5	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.6838303707748081	[318]	[924]	6	hSpCas9	negative selection	11142398
184632350	184632373	4	-	28162770	OCIAML5	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.2442595462110273	[209]	[448]	2	hSpCas9	negative selection	11142399
184632334	184632357	4	+	28162770	OCIAML5	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.8249764300988449	[262]	[840]	7	hSpCas9	negative selection	11142400
184631073	184631096	4	-	28162770	EOL1	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.45626825101471136	[183]	[132]	4	hSpCas9	negative selection	11311757
184631129	184631152	4	-	28162770	EOL1	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.5177137813170771	[642]	[484]	5	hSpCas9	negative selection	11311758
184631883	184631906	4	-	28162770	EOL1	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.040889482199732985	[1154]	[625]	0	hSpCas9	negative selection	11311759
184631147	184631170	4	-	28162770	EOL1	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	-0.41403766727043617	[391]	[154]	-3	hSpCas9	negative selection	11311760
184631026	184631049	4	+	28162770	EOL1	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.21601058573084564	[669]	[409]	2	hSpCas9	negative selection	11311761
184631111	184631134	4	-	28162770	EOL1	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	1.573969471926427	[444]	[697]	9	hSpCas9	negative selection	11311762
184631047	184631070	4	+	28162770	EOL1	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.3395852708493783	[461]	[307]	3	hSpCas9	negative selection	11311763
184635372	184635395	4	-	28162770	EOL1	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.41441594152255123	[694]	[487]	4	hSpCas9	negative selection	11311764
184632350	184632373	4	-	28162770	EOL1	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.477550672000811	[406]	[153]	-4	hSpCas9	negative selection	11311765
184632334	184632357	4	+	28162770	EOL1	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.4017642621092654	[578]	[402]	3	hSpCas9	negative selection	11311766
184631073	184631096	4	-	28162770	MOLM13	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	1.2048549757107851	[152]	[254]	8	hSpCas9	negative selection	11481123
184631129	184631152	4	-	28162770	MOLM13	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	-0.301587156999773	[732]	[429]	-2	hSpCas9	negative selection	11481124
184631883	184631906	4	-	28162770	MOLM13	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	1.1484155458953456	[880]	[1411]	8	hSpCas9	negative selection	11481125
184631147	184631170	4	-	28162770	MOLM13	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	1.3870773359564814	[256]	[485]	9	hSpCas9	negative selection	11481126
184631026	184631049	4	+	28162770	MOLM13	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	1.1929563924642161	[486]	[804]	8	hSpCas9	negative selection	11481127
184631111	184631134	4	-	28162770	MOLM13	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	1.4416918645941357	[388]	[763]	9	hSpCas9	negative selection	11481128
184631047	184631070	4	+	28162770	MOLM13	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.22783829371162423	[410]	[347]	1	hSpCas9	negative selection	11481129
184635372	184635395	4	-	28162770	MOLM13	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.6016984217367722	[781]	[857]	4	hSpCas9	negative selection	11481130
184632350	184632373	4	-	28162770	MOLM13	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.3547504061938439	[410]	[379]	2	hSpCas9	negative selection	11481131
184632334	184632357	4	+	28162770	MOLM13	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.550075136899824	[579]	[613]	4	hSpCas9	negative selection	11481132
184631073	184631096	4	-	28162770	HEL	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.0006324241755919502	[102]	[65]	0	hSpCas9	negative selection	11650489
184631129	184631152	4	-	28162770	HEL	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.5766496415425844	[535]	[511]	5	hSpCas9	negative selection	11650490
184631883	184631906	4	-	28162770	HEL	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	1.2348082192157728	[809]	[1220]	9	hSpCas9	negative selection	11650491
184631147	184631170	4	-	28162770	HEL	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.379704426166563	[287]	[239]	3	hSpCas9	negative selection	11650492
184631026	184631049	4	+	28162770	HEL	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.8350455271475135	[532]	[608]	7	hSpCas9	negative selection	11650493
184631111	184631134	4	-	28162770	HEL	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	1.5208804891272578	[320]	[589]	9	hSpCas9	negative selection	11650494
184631047	184631070	4	+	28162770	HEL	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.13053267371451482	[347]	[243]	1	hSpCas9	negative selection	11650495
184635372	184635395	4	-	28162770	HEL	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.4176422017355308	[622]	[532]	3	hSpCas9	negative selection	11650496
184632350	184632373	4	-	28162770	HEL	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.9557986980976103	[358]	[445]	8	hSpCas9	negative selection	11650497
184632334	184632357	4	+	28162770	HEL	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.9286815451441939	[478]	[583]	7	hSpCas9	negative selection	11650498
184631073	184631096	4	-	28162770	MV411	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.5162543092105751	[82]	[99]	4	hSpCas9	negative selection	11819855
184631129	184631152	4	-	28162770	MV411	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.3150234468387101	[416]	[436]	2	hSpCas9	negative selection	11819856
184631883	184631906	4	-	28162770	MV411	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.3271647432535094	[615]	[650]	3	hSpCas9	negative selection	11819857
184631147	184631170	4	-	28162770	MV411	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	-0.026556067040884965	[184]	[152]	0	hSpCas9	negative selection	11819858
184631026	184631049	4	+	28162770	MV411	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.5417680871061079	[379]	[465]	5	hSpCas9	negative selection	11819859
184631111	184631134	4	-	28162770	MV411	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.6556537842056052	[317]	[421]	6	hSpCas9	negative selection	11819860
184631047	184631070	4	+	28162770	MV411	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.8798926559827749	[248]	[385]	7	hSpCas9	negative selection	11819861
184635372	184635395	4	-	28162770	MV411	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.9737806572087215	[517]	[856]	8	hSpCas9	negative selection	11819862
184632350	184632373	4	-	28162770	MV411	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.32422812732492307	[323]	[217]	-2	hSpCas9	negative selection	11819863
184632334	184632357	4	+	28162770	MV411	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.5245777239232996	[457]	[554]	5	hSpCas9	negative selection	11819864
184631073	184631096	4	-	28162770	MONOMAC1	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	-0.13733060093528604	[70]	[73]	-1	hSpCas9	negative selection	11989221
184631129	184631152	4	-	28162770	MONOMAC1	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.29711936933689276	[305]	[430]	3	hSpCas9	negative selection	11989222
184631883	184631906	4	-	28162770	MONOMAC1	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.08853583260999276	[433]	[528]	0	hSpCas9	negative selection	11989223
184631147	184631170	4	-	28162770	MONOMAC1	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	-0.5624923174878371	[142]	[110]	-5	hSpCas9	negative selection	11989224
184631026	184631049	4	+	28162770	MONOMAC1	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.648885731257538	[231]	[416]	6	hSpCas9	negative selection	11989225
184631111	184631134	4	-	28162770	MONOMAC1	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	-0.19703684705955365	[186]	[186]	-2	hSpCas9	negative selection	11989226
184631047	184631070	4	+	28162770	MONOMAC1	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	1.2530913166876518	[197]	[540]	9	hSpCas9	negative selection	11989227
184635372	184635395	4	-	28162770	MONOMAC1	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.533356093183166	[351]	[583]	5	hSpCas9	negative selection	11989228
184632350	184632373	4	-	28162770	MONOMAC1	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.41829930270512106	[187]	[287]	4	hSpCas9	negative selection	11989229
184632334	184632357	4	+	28162770	MONOMAC1	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	-0.1741727387078167	[312]	[317]	-1	hSpCas9	negative selection	11989230
184631073	184631096	4	-	28162770	OCIAML2	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	0.36890550256459265	[18]	[135]	3	hSpCas9	negative selection	12158587
184631129	184631152	4	-	28162770	OCIAML2	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.09179010682790656	[85]	[507]	0	hSpCas9	negative selection	12158588
184631883	184631906	4	-	28162770	OCIAML2	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.7391511650142646	[118]	[1100]	7	hSpCas9	negative selection	12158589
184631147	184631170	4	-	28162770	OCIAML2	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.3194471053836073	[47]	[331]	3	hSpCas9	negative selection	12158590
184631026	184631049	4	+	28162770	OCIAML2	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.09669251634326437	[95]	[568]	0	hSpCas9	negative selection	12158591
184631111	184631134	4	-	28162770	OCIAML2	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	0.9816301379928813	[54]	[601]	8	hSpCas9	negative selection	12158592
184631047	184631070	4	+	28162770	OCIAML2	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.888451268062667	[45]	[471]	8	hSpCas9	negative selection	12158593
184635372	184635395	4	-	28162770	OCIAML2	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.20345856595197875	[101]	[650]	2	hSpCas9	negative selection	12158594
184632350	184632373	4	-	28162770	OCIAML2	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	0.8608843184743991	[44]	[452]	8	hSpCas9	negative selection	12158595
184632334	184632357	4	+	28162770	OCIAML2	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.7543365397581131	[59]	[560]	7	hSpCas9	negative selection	12158596
184631073	184631096	4	-	28162770	OCIAML3	viability	GGCGTGTCATAAAATACCAGTGG	CASP3	ENSG00000164305	-0.470625224818881	[27]	[60]	-4	hSpCas9	negative selection	12327953
184631129	184631152	4	-	28162770	OCIAML3	viability	CGTGGTACAGAACTGGACTGTGG	CASP3	ENSG00000164305	0.635474205798604	[115]	[543]	6	hSpCas9	negative selection	12327954
184631883	184631906	4	-	28162770	OCIAML3	viability	GTTTGTGTGCTTCTGAGCCATGG	CASP3	ENSG00000164305	0.3538696285997043	[154]	[597]	3	hSpCas9	negative selection	12327955
184631147	184631170	4	-	28162770	OCIAML3	viability	TCTAACACCCAGGCCTGCCGTGG	CASP3	ENSG00000164305	0.6496154590634097	[52]	[250]	6	hSpCas9	negative selection	12327956
184631026	184631049	4	+	28162770	OCIAML3	viability	AACGTTCTCACCAGGTGCTGTGG	CASP3	ENSG00000164305	0.648612589239986	[85]	[406]	6	hSpCas9	negative selection	12327957
184631111	184631134	4	-	28162770	OCIAML3	viability	TGTGGCATTGAGACAGACAGTGG	CASP3	ENSG00000164305	1.0462372958981825	[63]	[398]	8	hSpCas9	negative selection	12327958
184631047	184631070	4	+	28162770	OCIAML3	viability	GGAGTATGCATACAAGAAGTCGG	CASP3	ENSG00000164305	0.21824608114628008	[83]	[294]	2	hSpCas9	negative selection	12327959
184635372	184635395	4	-	28162770	OCIAML3	viability	AATGGACTCTGGAATATCCCTGG	CASP3	ENSG00000164305	0.45867267635201436	[120]	[501]	4	hSpCas9	negative selection	12327960
184632350	184632373	4	-	28162770	OCIAML3	viability	ATGTCGATGCAGCAAACCTCAGG	CASP3	ENSG00000164305	-0.04857350378964426	[73]	[215]	0	hSpCas9	negative selection	12327961
184632334	184632357	4	+	28162770	OCIAML3	viability	AGTTTCTGAATGTTTCCCTGAGG	CASP3	ENSG00000164305	0.7533430514431059	[89]	[457]	6	hSpCas9	negative selection	12327962