Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:837
• Symbol:CASP4
• Description:caspase 4

DataSource: http://genomecrispr.dkfz.de/#!/results/CASP4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
104948667	104948690	11	-	26472758	Jiyoye	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	1.009211395585971	[55]	[84]	6	hSpCas9	negative selection	23759
104949666	104949689	11	+	26472758	Jiyoye	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.15738308674061008	[628]	[528]	1	hSpCas9	negative selection	23760
104948596	104948619	11	-	26472758	Jiyoye	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.6391221095555701	[42]	[100]	8	hSpCas9	negative selection	23761
104951015	104951038	11	-	26472758	Jiyoye	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	-0.025784025770232866	[134]	[99]	0	hSpCas9	negative selection	23762
104951001	104951024	11	+	26472758	Jiyoye	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.3423242371559053	[90]	[86]	2	hSpCas9	negative selection	23763
104949757	104949780	11	-	26472758	Jiyoye	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.10909402857287864	[74]	[60]	0	hSpCas9	negative selection	23764
104951059	104951082	11	-	26472758	Jiyoye	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	-0.6342445458741073	[211]	[102]	-4	hSpCas9	negative selection	23765
104948563	104948586	11	-	26472758	Jiyoye	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	-0.364872671815778	[332]	[194]	-3	hSpCas9	negative selection	23766
104950968	104950991	11	-	26472758	Jiyoye	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.02633477784444914	[130]	[96]	0	hSpCas9	negative selection	23767
104949680	104949703	11	-	26472758	Jiyoye	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	-0.9114323550898776	[216]	[86]	-6	hSpCas9	negative selection	23768
104948667	104948690	11	-	26472758	KBM7	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.32957428046970083	[546,316]	[210,283]	3	hSpCas9	negative selection	214877
104949666	104949689	11	+	26472758	KBM7	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.7357285068768058	[2772,2276]	[2178,1776]	7	hSpCas9	negative selection	214878
104948596	104948619	11	-	26472758	KBM7	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.305781591637974	[224,187]	[238,238]	9	hSpCas9	negative selection	214879
104951015	104951038	11	-	26472758	KBM7	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.8947118193722602	[370,269]	[285,268]	8	hSpCas9	negative selection	214880
104951001	104951024	11	+	26472758	KBM7	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	1.0485518533534302	[378,213]	[270,290]	9	hSpCas9	negative selection	214881
104949757	104949780	11	-	26472758	KBM7	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.60620677843117	[392,192]	[138,260]	6	hSpCas9	negative selection	214882
104951059	104951082	11	-	26472758	KBM7	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.06308615437679721	[699,553]	[280,327]	0	hSpCas9	negative selection	214883
104948563	104948586	11	-	26472758	KBM7	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.2065884399807527	[841,880]	[455,483]	2	hSpCas9	negative selection	214884
104950968	104950991	11	-	26472758	KBM7	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	0.6409472042104642	[410,236]	[341,133]	7	hSpCas9	negative selection	214885
104949680	104949703	11	-	26472758	KBM7	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.6717564529119515	[656,833]	[503,624]	7	hSpCas9	negative selection	214886
104948667	104948690	11	-	26472758	Raji	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	1.3577068894578395	[189]	[112]	9	hSpCas9	negative selection	405995
104949666	104949689	11	+	26472758	Raji	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.45559385660861773	[1435]	[456]	4	hSpCas9	negative selection	405996
104948596	104948619	11	-	26472758	Raji	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.4468700016452662	[97]	[61]	9	hSpCas9	negative selection	405997
104951015	104951038	11	-	26472758	Raji	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.4699536147583078	[251]	[80]	4	hSpCas9	negative selection	405998
104951001	104951024	11	+	26472758	Raji	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	-0.3607653003648069	[165]	[29]	-3	hSpCas9	negative selection	405999
104949757	104949780	11	-	26472758	Raji	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.11052149497053465	[106]	[22]	-1	hSpCas9	negative selection	406000
104951059	104951082	11	-	26472758	Raji	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	-0.18945357855093253	[284]	[57]	-2	hSpCas9	negative selection	406001
104948563	104948586	11	-	26472758	Raji	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.6836463411443705	[498]	[185]	6	hSpCas9	negative selection	406002
104950968	104950991	11	-	26472758	Raji	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.6923178141405693	[187]	[26]	-5	hSpCas9	negative selection	406003
104949680	104949703	11	-	26472758	Raji	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.8291768179155554	[324]	[133]	7	hSpCas9	negative selection	406004
104948667	104948690	11	-	26472758	K562	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.24861871619573267	[342]	[343]	2	hSpCas9	negative selection	597113
104949666	104949689	11	+	26472758	K562	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.6482580203404269	[2036]	[2694]	5	hSpCas9	negative selection	597114
104948596	104948619	11	-	26472758	K562	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.2145481980843091	[121]	[238]	8	hSpCas9	negative selection	597115
104951015	104951038	11	-	26472758	K562	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.7334568083890676	[227]	[319]	6	hSpCas9	negative selection	597116
104951001	104951024	11	+	26472758	K562	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	1.4955510444439493	[141]	[337]	9	hSpCas9	negative selection	597117
104949757	104949780	11	-	26472758	K562	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.6670445977318957	[157]	[83]	-4	hSpCas9	negative selection	597118
104951059	104951082	11	-	26472758	K562	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	1.138527559075709	[324]	[603]	8	hSpCas9	negative selection	597119
104948563	104948586	11	-	26472758	K562	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	1.1271318396774963	[697]	[1286]	8	hSpCas9	negative selection	597120
104950968	104950991	11	-	26472758	K562	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	0.3121055351780216	[228]	[239]	2	hSpCas9	negative selection	597121
104949680	104949703	11	-	26472758	K562	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.09084100784129978	[712]	[640]	0	hSpCas9	negative selection	597122
104950907	104950930	11	+	26627737	DLD1	viability	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.3298287018303377	[630]	[344,243,166]	3	hSpCas9	negative selection	776502
104954939	104954962	11	+	26627737	DLD1	viability	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-0.27421094894196774	[186]	[79,46,21]	-3	hSpCas9	negative selection	776503
104950907	104950930	11	+	26627737	GBM cells	viability after 5 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	-0.030450582521254155	[278]	[178,113]	0	hSpCas9	negative selection	858817
104954939	104954962	11	+	26627737	GBM cells	viability after 5 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-0.021358932643580297	[175]	[91,93]	0	hSpCas9	negative selection	858818
104950907	104950930	11	+	26627737	GBM cells	viability after 13 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	-0.1670110218773656	[278]	[216,67]	-2	hSpCas9	negative selection	941132
104954939	104954962	11	+	26627737	GBM cells	viability after 13 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-0.3772232334777848	[175]	[83,64]	-4	hSpCas9	negative selection	941133
104950907	104950930	11	+	26627737	GBM cells	viability after 21 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	-0.7994712509409942	[278]	[84,88]	-6	hSpCas9	negative selection	1023447
104954939	104954962	11	+	26627737	GBM cells	viability after 21 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-0.1876444289629437	[175]	[84,82]	-2	hSpCas9	negative selection	1023448
104950907	104950930	11	+	26627737	RPE1	viability after 9 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.6381635069586044	[741]	[347,378]	4	hSpCas9	negative selection	1105762
104954939	104954962	11	+	26627737	RPE1	viability after 9 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	0.3673066420759883	[274]	[107,114]	2	hSpCas9	negative selection	1105763
104950907	104950930	11	+	26627737	RPE1	viability after 12 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.6748851186832645	[741]	[309,326]	4	hSpCas9	negative selection	1188077
104954939	104954962	11	+	26627737	RPE1	viability after 12 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	0.14584436863933248	[274]	[55,108]	1	hSpCas9	negative selection	1188078
104950907	104950930	11	+	26627737	RPE1	viability after 15 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.7048985328956789	[741]	[446,240]	4	hSpCas9	negative selection	1270392
104954939	104954962	11	+	26627737	RPE1	viability after 15 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-0.0678573718462101	[274]	[61,85]	0	hSpCas9	negative selection	1270393
104950907	104950930	11	+	26627737	RPE1	viability after 18 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.2644138966200174	[741]	[211,270]	1	hSpCas9	negative selection	1352707
104954939	104954962	11	+	26627737	RPE1	viability after 18 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-0.08014250571323545	[274]	[46,94]	0	hSpCas9	negative selection	1352708
104950907	104950930	11	+	26627737	HeLa	viability after 8 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	-0.1094190407985906	[517]	[102,224,270]	-1	hSpCas9	negative selection	1435022
104954939	104954962	11	+	26627737	HeLa	viability after 8 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-0.6228683239311209	[391]	[87,64,169]	-6	hSpCas9	negative selection	1435023
104950907	104950930	11	+	26627737	HeLa	viability after 12 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.8140106192209291	[517]	[662,332,145]	6	hSpCas9	negative selection	1517337
104954939	104954962	11	+	26627737	HeLa	viability after 12 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-1.016566650658297	[391]	[115,25,104]	-7	hSpCas9	negative selection	1517338
104950907	104950930	11	+	26627737	HeLa	viability after 15 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.7401199133745955	[517]	[570,249,222]	6	hSpCas9	negative selection	1599652
104954939	104954962	11	+	26627737	HeLa	viability after 15 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-1.4254404602945714	[391]	[0,33,150]	-8	hSpCas9	negative selection	1599653
104950907	104950930	11	+	26627737	HeLa	viability after 18 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.6695063159300421	[517]	[351,204,222]	5	hSpCas9	negative selection	1681967
104954939	104954962	11	+	26627737	HeLa	viability after 18 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-1.4228619715319581	[391]	[0,27,150]	-8	hSpCas9	negative selection	1681968
104950907	104950930	11	+	26627737	HCT116	viability after 6 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	1.3663611255623165	[533]	[131,262]	7	hSpCas9	negative selection	1764282
104954939	104954962	11	+	26627737	HCT116	viability after 6 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	1.549206657837991	[209]	[133,75]	7	hSpCas9	negative selection	1764283
104950907	104950930	11	+	26627737	HCT116	viability after 8 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	-0.20071258935639957	[470]	[323,192,162]	-2	hSpCas9	negative selection	1846597
104954939	104954962	11	+	26627737	HCT116	viability after 8 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	1.1103330174812513	[108]	[88,145,152]	8	hSpCas9	negative selection	1846598
104950907	104950930	11	+	26627737	HCT116	viability after 9 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.7059117584762763	[533]	[350,138]	5	hSpCas9	negative selection	1928912
104954939	104954962	11	+	26627737	HCT116	viability after 9 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	0.8874299242537764	[209]	[215,14]	6	hSpCas9	negative selection	1928913
104950907	104950930	11	+	26627737	HCT116	viability after 12 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	-0.46713284984998465	[470]	[185,196,153]	-5	hSpCas9	negative selection	2011227
104954939	104954962	11	+	26627737	HCT116	viability after 12 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	1.642230029611881	[108]	[133,287,120]	9	hSpCas9	negative selection	2011228
104950907	104950930	11	+	26627737	HCT116	viability after 15 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	-0.44222459045713525	[470]	[223,236,139]	-4	hSpCas9	negative selection	2093542
104954939	104954962	11	+	26627737	HCT116	viability after 15 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	1.0831660286675764	[108]	[95,212,84]	8	hSpCas9	negative selection	2093543
104950907	104950930	11	+	26627737	HCT116	viability after 18 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	-0.2153643563725829	[470]	[215,216,151]	-2	hSpCas9	negative selection	2175857
104954939	104954962	11	+	26627737	HCT116	viability after 18 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	1.671903447990469	[108]	[182,244,65]	9	hSpCas9	negative selection	2175858
104954966	104954989	11	-	24717434	HeLa	essential genes for diphteria toxin toxicity	AAAAAAGCCACTTAAGGTGTTGG	CASP4	ENSG00000196954	0.6380450262849776	[1797,1481,1587]	[0,0,0]	2	hSpCas9	positive selection	2380648
104954844	104954867	11	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CTAAAACTGAAGACAAAGTTCGG	CASP4	ENSG00000196954	-1.3472809121741598	[6949,5706,6604]	[0,0,0]	-9	hSpCas9	positive selection	2380649
104954803	104954826	11	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CAAGAGAAGCAACGTATGGCAGG	CASP4	ENSG00000196954	0.1333244509933402	[2442,2258,2196]	[0,0,0]	0	hSpCas9	positive selection	2380650
104954966	104954989	11	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AAAAAAGCCACTTAAGGTGTTGG	CASP4	ENSG00000196954	0.6379950446414739	[1797,1481,1587]	[0,0,0]	1	hSpCas9	positive selection	2381786
104954966	104954989	11	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AAAAAAGCCACTTAAGGTGTTGG	CASP4	ENSG00000196954	0.6379950446414739	[1797,1481,1587]	[0,0,0]	1	hSpCas9	positive selection	2381787
104954844	104954867	11	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTAAAACTGAAGACAAAGTTCGG	CASP4	ENSG00000196954	2.425442863384423	[6949,5706,6604]	[0,38,0]	5	hSpCas9	positive selection	2381788
104954844	104954867	11	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTAAAACTGAAGACAAAGTTCGG	CASP4	ENSG00000196954	2.425442863384423	[6949,5706,6604]	[0,38,0]	5	hSpCas9	positive selection	2381789
104954803	104954826	11	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CAAGAGAAGCAACGTATGGCAGG	CASP4	ENSG00000196954	0.1330592346768568	[2442,2258,2196]	[0,0,0]	0	hSpCas9	positive selection	2381790
104954803	104954826	11	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CAAGAGAAGCAACGTATGGCAGG	CASP4	ENSG00000196954	0.1330592346768568	[2442,2258,2196]	[0,0,0]	0	hSpCas9	positive selection	2381791
104968764	104968787	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGCTGAGGTGTCAACCCACAGG	CASP4	ENSG00000196954	-1.2039796322347192	[223,302]	[6,43]	-7	dCas9-VP64	positive selection	2413033
104968711	104968734	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGGAATTTAGTTTCTGACTTGG	CASP4	ENSG00000196954	0.6645419240685975	[64,147]	[39,33]	3	dCas9-VP64	positive selection	2413034
104968692	104968715	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAAATTGGCATCCAATTACTGG	CASP4	ENSG00000196954	-0.06469991916934736	[183,81]	[47,4]	0	dCas9-VP64	positive selection	2413035
104956804	104956827	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAAACAGAAGCCCAGAACTCAGG	CASP4	ENSG00000196954	-2.0368183727951807	[108,97]	[6,2]	-9	dCas9-VP64	positive selection	2461244
104956979	104957002	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAAACCCTTTCTCTAAGATCAGG	CASP4	ENSG00000196954	0.4802568110779677	[340,542]	[171,96]	2	dCas9-VP64	positive selection	2461245
104968764	104968787	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGCTGAGGTGTCAACCCACAGG	CASP4	ENSG00000196954	4.688039378097525	[110,176]	[2439,64]	9	dCas9-VP64	positive selection	2508288
104968711	104968734	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGGAATTTAGTTTCTGACTTGG	CASP4	ENSG00000196954	1.2543511862267946	[157,172]	[42,209]	7	dCas9-VP64	positive selection	2508289
104968692	104968715	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAAATTGGCATCCAATTACTGG	CASP4	ENSG00000196954	4.255369817813297	[169,262]	[56,2561]	9	dCas9-VP64	positive selection	2508290
104956804	104956827	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAAACAGAAGCCCAGAACTCAGG	CASP4	ENSG00000196954	0.13084273294048276	[88,122]	[33,40]	1	dCas9-VP64	positive selection	2556499
104956979	104957002	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAAACCCTTTCTCTAAGATCAGG	CASP4	ENSG00000196954	1.414900290727879	[55,33]	[41,36]	7	dCas9-VP64	positive selection	2556500
104951041	104951064	11	+	27013184	SW480	treatment with recombinant TRAIL	TATTGCATATGATGAGAGCCAGG	CASP4	ENSG00000196954	-0.36381210936318353	[258,132]	[34,113]	-2	hSpCas9	positive selection	2960469
104948599	104948622	11	-	27013184	SW480	treatment with recombinant TRAIL	TTCACAGTCATCTGAGAACCTAG	CASP4	ENSG00000196954	1.5631899527460433	[86,205]	[196,155]	7	hSpCas9	positive selection	2960481
104948632	104948655	11	-	27013184	SW480	treatment with recombinant TRAIL	CAGAGACTCTCCAGCATCCTTGG	CASP4	ENSG00000196954	0.573607889544426	[261,479]	[184,298]	3	hSpCas9	positive selection	2960484
104968506	104968529	11	+	27013184	SW480	treatment with recombinant TRAIL	GAAAAGGACTCACCTGCCATAGG	CASP4	ENSG00000196954	-3.811189874771764	[39,94]	[1,1]	-9	hSpCas9	positive selection	2966396
104968507	104968530	11	+	27013184	SW480	treatment with recombinant TRAIL	AAAAGGACTCACCTGCCATAGGG	CASP4	ENSG00000196954	1.3438019427490737	[413,742]	[596,646]	6	hSpCas9	positive selection	2966397
104948615	104948638	11	+	27013184	SW480	treatment with recombinant TRAIL	CTGTGAAGAGGCCACTTCCAAGG	CASP4	ENSG00000196954	0.42572523522093264	[335,266]	[145,219]	2	hSpCas9	positive selection	2966398
104948660	104948683	11	+	27013184	SW480	treatment with recombinant TRAIL	CAGTTCCCCACGGTTTGCTATGG	CASP4	ENSG00000196954	0.0440825522852798	[171,80]	[48,70]	0	hSpCas9	positive selection	2966399
104968498	104968521	11	-	27013184	SW480	treatment with recombinant TRAIL	AGGTGAGTCCTTTTCTGACTAGG	CASP4	ENSG00000196954	-0.38560440551078323	[428,745]	[136,263]	-2	hSpCas9	positive selection	2966400
104954924	104954947	11	+	27013184	SW480	treatment with recombinant TRAIL	AGTTATCCAAAACACCAGTGAGG	CASP4	ENSG00000196954	0.7374018885810606	[291,230]	[154,239]	3	hSpCas9	positive selection	2966401
104954939	104954962	11	+	27013184	SW480	treatment with recombinant TRAIL	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	3.0782889264248476	[129,91]	[380,452]	9	hSpCas9	positive selection	2966402
104947082	104947105	11	-	27013184	SW480	treatment with recombinant TRAIL	CCTAGAGGAAGTATTTCGGAAGG	CASP4	ENSG00000196954	-1.8492666127384774	[349,626]	[94,2]	-7	hSpCas9	positive selection	2966403
104954940	104954963	11	+	27013184	SW480	treatment with recombinant TRAIL	AGTGAGGAAATCTTTGCCCAGGG	CASP4	ENSG00000196954	0.015419695243436116	[263,351]	[111,161]	0	hSpCas9	positive selection	2966404
104947086	104947109	11	-	27013184	SW480	treatment with recombinant TRAIL	GCCACCTAGAGGAAGTATTTCGG	CASP4	ENSG00000196954	0.8479828873984389	[46,114]	[67,49]	4	hSpCas9	positive selection	2966405
104968518	104968541	11	-	27013184	SW480	treatment with recombinant TRAIL	CAGAGGCTGTTCCCTATGGCAGG	CASP4	ENSG00000196954	0.6856461353445402	[598,398]	[309,412]	3	hSpCas9	positive selection	2966407
104947162	104947185	11	-	27013184	SW480	treatment with recombinant TRAIL	TCCTGGAGAGACAGCACAATGGG	CASP4	ENSG00000196954	0.24927338033044505	[222,312]	[212,24]	1	hSpCas9	positive selection	2966408
104947179	104947202	11	-	27013184	SW480	treatment with recombinant TRAIL	TCATTATAGACAACGTGTCCTGG	CASP4	ENSG00000196954	-1.1092391994929542	[1,25]	[2,1]	-5	hSpCas9	positive selection	2966409
104948656	104948679	11	-	27013184	SW480	treatment with recombinant TRAIL	AGCAAACCGTGGGGAACTGTGGG	CASP4	ENSG00000196954	-0.25155433041274233	[362,650]	[167,194]	-1	hSpCas9	positive selection	2966410
104968522	104968545	11	-	27013184	SW480	treatment with recombinant TRAIL	AGGACAGAGGCTGTTCCCTATGG	CASP4	ENSG00000196954	0.2816097142306626	[84,103]	[18,91]	1	hSpCas9	positive selection	2966411
104948657	104948680	11	-	27013184	SW480	treatment with recombinant TRAIL	TAGCAAACCGTGGGGAACTGTGG	CASP4	ENSG00000196954	0.5542394500915487	[250,197]	[151,131]	2	hSpCas9	positive selection	2966412
104948665	104948688	11	-	27013184	SW480	treatment with recombinant TRAIL	TGTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.6123972776037456	[99,40]	[46,49]	3	hSpCas9	positive selection	2966413
104948666	104948689	11	-	27013184	SW480	treatment with recombinant TRAIL	ATGTCTCCATAGCAAACCGTGGG	CASP4	ENSG00000196954	-1.988767459695081	[86,186]	[13,14]	-7	hSpCas9	positive selection	2966414
104948667	104948690	11	-	27013184	SW480	treatment with recombinant TRAIL	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.8648674794272813	[346,376]	[164,451]	4	hSpCas9	positive selection	2966415
104954737	104954760	11	-	27013184	SW480	treatment with recombinant TRAIL	CCCAATAAAAAAGGTAAGACTGG	CASP4	ENSG00000196954	-1.8491812755227959	[28,1]	[1,1]	-7	hSpCas9	positive selection	2966416
104954807	104954830	11	-	27013184	SW480	treatment with recombinant TRAIL	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.21079455551208695	[250,274]	[88,109]	-1	hSpCas9	positive selection	2966417
104954894	104954917	11	-	27013184	SW480	treatment with recombinant TRAIL	ACAAAATGTACTGAACTGGAAGG	CASP4	ENSG00000196954	0.9495596815058682	[27,54]	[7,69]	4	hSpCas9	positive selection	2966418
104954898	104954921	11	-	27013184	SW480	treatment with recombinant TRAIL	TGGAACAAAATGTACTGAACTGG	CASP4	ENSG00000196954	-0.6826445410785604	[48,69]	[23,3]	-3	hSpCas9	positive selection	2966419
104954921	104954944	11	-	27013184	SW480	treatment with recombinant TRAIL	CACTGGTGTTTTGGATAACTTGG	CASP4	ENSG00000196954	2.263168918572864	[185,189]	[405,364]	8	hSpCas9	positive selection	2966420
104954930	104954953	11	-	27013184	SW480	treatment with recombinant TRAIL	AGATTTCCTCACTGGTGTTTTGG	CASP4	ENSG00000196954	1.1699230751305958	[216,351]	[191,381]	5	hSpCas9	positive selection	2966421
104954938	104954961	11	-	27013184	SW480	treatment with recombinant TRAIL	CTGGGCAAAGATTTCCTCACTGG	CASP4	ENSG00000196954	-1.2775789452781614	[260,527]	[70,63]	-5	hSpCas9	positive selection	2966422
104954998	104955021	11	-	27013184	SW480	treatment with recombinant TRAIL	ATCTTTCTATTTCTAACAGAAGG	CASP4	ENSG00000196954	-2.500849780393354	[57,38]	[4,1]	-8	hSpCas9	positive selection	2966423
104947082	104947105	11	+	27013184	SW480	treatment with recombinant TRAIL	CCTTCCGAAATACTTCCTCTAGG	CASP4	ENSG00000196954	1.9153826028128038	[391,354]	[582,649]	8	hSpCas9	positive selection	2966424
104947085	104947108	11	+	27013184	SW480	treatment with recombinant TRAIL	TCCGAAATACTTCCTCTAGGTGG	CASP4	ENSG00000196954	0.4254332703144046	[1,12]	[1,6]	2	hSpCas9	positive selection	2966425
104947106	104947129	11	+	27013184	SW480	treatment with recombinant TRAIL	GGCAGCACCAAGAATATTTCTGG	CASP4	ENSG00000196954	-2.32603155250484	[544,238]	[24,48]	-8	hSpCas9	positive selection	2966426
104951002	104951025	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.26996146096255536	[4,4]	[5,4]	6	hSpCas9	positive selection	2976415
104950988	104951011	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCTGACTTTGACATCACAGGG	CASP4	ENSG00000196954	-0.07964254209993486	[2,3]	[2,2]	-1	hSpCas9	positive selection	2976416
104950968	104950991	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	0.24116580548460081	[2,3]	[1,4]	5	hSpCas9	positive selection	2976417
104951961	104951984	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGATTCTCCTGACTCAGGTGG	CASP4	ENSG00000196954	-0.350663740126387	[3,3]	[2,1]	-5	hSpCas9	positive selection	2976418
104951002	104951025	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.17633993583943797	[4,4]	[4,3]	3	hSpCas9	positive selection	3044273
104950988	104951011	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCTGACTTTGACATCACAGGG	CASP4	ENSG00000196954	0.29305219277404193	[2,2]	[2,2]	5	hSpCas9	positive selection	3044274
104950968	104950991	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	0.14936758483387058	[2,2]	[3,0]	2	hSpCas9	positive selection	3044275
104951961	104951984	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGATTCTCCTGACTCAGGTGG	CASP4	ENSG00000196954	0.06758651388176082	[3,3]	[3,1]	1	hSpCas9	positive selection	3044276
104954959	104954982		+	24336571	A375	resistance to PLX after 7 days	AGGGATTCCAACACCTTAAGTGG	CASP4	ENSG00000196954	-0.22093067339924954	[5,5]	[4,4]	-6	hSpCas9	positive selection	3160733
104954807	104954830		-	24336571	A375	resistance to PLX after 7 days	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.1895202410405359	[26,23]	[20,22]	-6	hSpCas9	positive selection	3160735
104951991	104952014		-	24336571	A375	resistance to PLX after 7 days	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	-0.04251990049922161	[47,49]	[43,49]	-1	hSpCas9	positive selection	3160736
104954959	104954982		+	24336571	A375	resistance to PLX after 14 days	AGGGATTCCAACACCTTAAGTGG	CASP4	ENSG00000196954	0.1570295678878213	[5,3]	[1,1]	1	hSpCas9	positive selection	3218526
104954807	104954830		-	24336571	A375	resistance to PLX after 14 days	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.7442559583521898	[26,29]	[8,5]	-8	hSpCas9	positive selection	3218528
104951991	104952014		-	24336571	A375	resistance to PLX after 14 days	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	-0.16767588807010214	[45,57]	[19,22]	-2	hSpCas9	positive selection	3218529
104954959	104954982		+	24336571	A375	viability after 7 days	AGGGATTCCAACACCTTAAGTGG	CASP4	ENSG00000196954	0.013365574395169277	[5]	[5,5]	0	hSpCas9	negative selection	3276319
104954807	104954830		-	24336571	A375	viability after 7 days	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.13872321576199553	[23]	[26,23]	2	hSpCas9	negative selection	3276321
104951991	104952014		-	24336571	A375	viability after 7 days	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.754743531725492	[29]	[47,49]	9	hSpCas9	negative selection	3276322
104954959	104954982		+	24336571	A375	viability after 14 days	AGGGATTCCAACACCTTAAGTGG	CASP4	ENSG00000196954	-0.2736176660436358	[5]	[5,3]	-3	hSpCas9	negative selection	3334112
104954807	104954830		-	24336571	A375	viability after 14 days	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.3225738582126525	[23]	[26,29]	4	hSpCas9	negative selection	3334114
104951991	104952014		-	24336571	A375	viability after 14 days	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.8648659277798119	[29]	[45,57]	9	hSpCas9	negative selection	3334115
104951991	104952014	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	-1.076457627239299	[343,300]	[0,0]	-7	hSpCas9	positive selection	3341124
104951059	104951082	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	3.146338554251614	[214,216]	[0,23]	8	hSpCas9	positive selection	3341125
104954807	104954830	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	1.9127885448296809	[52,68]	[0,1]	7	hSpCas9	positive selection	3341126
104951015	104951038	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	-0.6674862921599458	[485,485]	[1,1]	-4	hSpCas9	positive selection	3360372
104949757	104949780	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	1.4759664979211755	[54,54]	[0,0]	6	hSpCas9	positive selection	3360373
104949582	104949605	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	-0.20210540719146217	[175,175]	[0,0]	-1	hSpCas9	positive selection	3360374
104951001	104951024	11	+	26780180	HT29	viability (Avana library 4 designs)	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.266102286542093	[]	[]	0	hSpCas9	negative selection	3412696
104950988	104951011	11	-	26780180	HT29	viability (Avana library 4 designs)	GAGCTGACTTTGACATCACAGGG	CASP4	ENSG00000196954	0.274833503047912	[]	[]	1	hSpCas9	negative selection	3412697
104950968	104950991	11	-	26780180	HT29	viability (Avana library 4 designs)	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	1.05611868343664	[]	[]	4	hSpCas9	negative selection	3412698
104951960	104951983	11	+	26780180	HT29	viability (Avana library 4 designs)	GTAGATTCTCCTGACTCAGGTGG	CASP4	ENSG00000196954	0.479458589018881	[]	[]	1	hSpCas9	negative selection	3412699
104950988	104951011	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCTGACTTTGACATCACAGGG	CASP4	ENSG00000196954	0.879068185891227	[]	[]	1	hSpCas9	negative selection	3488292
104950968	104950991	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	2.99601172579942	[]	[]	4	hSpCas9	negative selection	3488293
104951001	104951024	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	2.10256218373329	[]	[]	3	hSpCas9	negative selection	3488294
104951960	104951983	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGATTCTCCTGACTCAGGTGG	CASP4	ENSG00000196954	-1.28469602052402	[]	[]	-1	hSpCas9	negative selection	3488295
104949681	104949704	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGTCTCATGGCATCCTGGAGG	CASP4	ENSG00000196954	-9.91954834286632	[]	[]	-7	hSpCas9	negative selection	3488296
104954807	104954830	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	1.81329243214667	[]	[]	2	hSpCas9	negative selection	3488297
104950988	104951011	11	-	26780180	A375	viability (Avana lentiGuide)	GAGCTGACTTTGACATCACAGGG	CASP4	ENSG00000196954	1.46499791758461	[]	[]	1	hSpCas9	negative selection	3596951
104950968	104950991	11	-	26780180	A375	viability (Avana lentiGuide)	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	0.716062364206563	[]	[]	0	hSpCas9	negative selection	3596952
104951001	104951024	11	+	26780180	A375	viability (Avana lentiGuide)	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.28380293359512	[]	[]	0	hSpCas9	negative selection	3596953
104951960	104951983	11	+	26780180	A375	viability (Avana lentiGuide)	GTAGATTCTCCTGACTCAGGTGG	CASP4	ENSG00000196954	-1.15921251601817	[]	[]	-2	hSpCas9	negative selection	3596954
104949681	104949704	11	-	26780180	A375	viability (Avana lentiGuide)	CATGTCTCATGGCATCCTGGAGG	CASP4	ENSG00000196954	13.0021863845362	[]	[]	7	hSpCas9	negative selection	3596955
104954807	104954830	11	-	26780180	A375	viability (Avana lentiGuide)	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-2.64166399392248	[]	[]	-5	hSpCas9	negative selection	3596956
104950988	104951011	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCTGACTTTGACATCACAGGG	CASP4	ENSG00000196954	0.024029878663409224	[5]	[5,4]	0	hSpCas9	positive selection	3705610
104950968	104950991	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.16951716247095022	[4]	[3,3]	-3	hSpCas9	positive selection	3705611
104951001	104951024	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.009241937041280401	[6]	[5,5]	0	hSpCas9	positive selection	3705612
104951960	104951983	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGATTCTCCTGACTCAGGTGG	CASP4	ENSG00000196954	-0.10879433342077276	[4]	[4,4]	-2	hSpCas9	positive selection	3705613
104949681	104949704	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGTCTCATGGCATCCTGGAGG	CASP4	ENSG00000196954	-0.27103379082208573	[3]	[3,1]	-4	hSpCas9	positive selection	3705614
104954807	104954830	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.051762548008394804	[5]	[5,5]	-1	hSpCas9	positive selection	3705615
104950988	104951011	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCTGACTTTGACATCACAGGG	CASP4	ENSG00000196954	0.2729877353315107	[5]	[5,5]	7	hSpCas9	positive selection	3814217
104950968	104950991	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.7674606108185733	[4]	[1,2]	-7	hSpCas9	positive selection	3814218
104951001	104951024	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.14574036145993413	[6]	[6,6]	3	hSpCas9	positive selection	3814219
104951960	104951983	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGATTCTCCTGACTCAGGTGG	CASP4	ENSG00000196954	-0.049409776556686755	[5]	[3,5]	0	hSpCas9	positive selection	3814220
104949681	104949704	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGTCTCATGGCATCCTGGAGG	CASP4	ENSG00000196954	-0.05054258912356435	[4]	[4,1]	0	hSpCas9	positive selection	3814221
104954807	104954830	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.14792993593825401	[5]	[5,4]	3	hSpCas9	positive selection	3814222
104949757	104949780	11	-	26780180	A375	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	1.03538061297851	[]	[]	5	hSpCas9	negative selection	3922517
104951015	104951038	11	-	26780180	A375	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.294627201118044	[]	[]	0	hSpCas9	negative selection	3922518
104949582	104949605	11	-	26780180	A375	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.740854260013438	[]	[]	2	hSpCas9	negative selection	3922519
104951059	104951082	11	-	26780180	A375	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.415343211541801	[]	[]	1	hSpCas9	negative selection	3922520
104954807	104954830	11	-	26780180	A375	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	1.03333108144678	[]	[]	5	hSpCas9	negative selection	3922521
104951991	104952014	11	-	26780180	A375	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.379760869376281	[]	[]	0	hSpCas9	negative selection	3922522
104949757	104949780	11	-	26780180	HT29	viability (GeCKOv2 library)	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.853116015553971	[]	[]	3	hSpCas9	negative selection	4030483
104951015	104951038	11	-	26780180	HT29	viability (GeCKOv2 library)	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.196577910827074	[]	[]	0	hSpCas9	negative selection	4030484
104949582	104949605	11	-	26780180	HT29	viability (GeCKOv2 library)	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	1.09561267463688	[]	[]	5	hSpCas9	negative selection	4030485
104951059	104951082	11	-	26780180	HT29	viability (GeCKOv2 library)	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.952336388177243	[]	[]	4	hSpCas9	negative selection	4030486
104954807	104954830	11	-	26780180	HT29	viability (GeCKOv2 library)	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.713111406477769	[]	[]	2	hSpCas9	negative selection	4030487
104951991	104952014	11	-	26780180	HT29	viability (GeCKOv2 library)	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.300010559365158	[]	[]	0	hSpCas9	negative selection	4030488
104954959	104954982	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGGGATTCCAACACCTTAAGTGG	CASP4	ENSG00000196954	-0.15059433427579821	[2]	[1,0]	-4	hSpCas9	positive selection	4188826
104954807	104954830	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.07676516656992219	[4]	[2,2]	-2	hSpCas9	positive selection	4188828
104951991	104952014	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.3398574744185364	[5]	[5,4]	7	hSpCas9	positive selection	4188829
104954959	104954982	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGGGATTCCAACACCTTAAGTGG	CASP4	ENSG00000196954	0.2799150330935668	[1]	[0,0,0,0]	2	hSpCas9	positive selection	4252848
104954807	104954830	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.0512932248951512	[4]	[3,4,1,0]	0	hSpCas9	positive selection	4252850
104951991	104952014	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	-0.0021694106487790132	[5]	[2,4,3,0]	0	hSpCas9	positive selection	4252851
104951991	104952014	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.2582340768295693	[4]	[3,3]	5	hSpCas9	positive selection	4261012
104951059	104951082	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.2691478058107206	[3]	[3,3]	5	hSpCas9	positive selection	4261013
104954807	104954830	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.04266683677048572	[2]	[1,1]	0	hSpCas9	positive selection	4261014
104951015	104951038	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.47273758165075563	[3]	[3,4]	8	hSpCas9	positive selection	4325290
104949757	104949780	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.22771357676423054	[1]	[1,1]	4	hSpCas9	positive selection	4325291
104949582	104949605	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.2091644445488401	[2]	[3,1]	4	hSpCas9	positive selection	4325292
104948665	104948687	11	-	27760321	OCIAML3	viability	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.06919828767155162	[642,550]	[493,480]	0	hSpCas9	negative selection	4385805
104950963	104950985	11	-	27760321	OCIAML3	viability	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.9543542435088421	[674,525]	[967,819]	9	hSpCas9	negative selection	4385806
104950981	104951003	11	-	27760321	OCIAML3	viability	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.5968839250315974	[263,207]	[170,415]	7	hSpCas9	negative selection	4385807
104951002	104951024	11	+	27760321	OCIAML3	viability	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.4341312434596617	[908,745]	[831,919]	5	hSpCas9	negative selection	4385808
104951991	104952013	11	-	27760321	OCIAML3	viability	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.30856729589467535	[442,344]	[368,391]	3	hSpCas9	negative selection	4385809
104948665	104948687	11	-	27760321	OCIAML2	viability	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.4524780273834778	[642,550]	[575,767]	6	hSpCas9	negative selection	4469268
104950963	104950985	11	-	27760321	OCIAML2	viability	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.11566601371112595	[674,525]	[482,574]	1	hSpCas9	negative selection	4469269
104950981	104951003	11	-	27760321	OCIAML2	viability	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.37949112323402534	[263,207]	[219,281]	5	hSpCas9	negative selection	4469270
104951002	104951024	11	+	27760321	OCIAML2	viability	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.2592559313073505	[908,745]	[745,864]	3	hSpCas9	negative selection	4469271
104951991	104952013	11	-	27760321	OCIAML2	viability	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.4333494136795277	[442,344]	[344,535]	6	hSpCas9	negative selection	4469272
104948665	104948687	11	-	27760321	MV411	viability	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.652840658508894	[642,550]	[527,751]	5	hSpCas9	negative selection	4552731
104950963	104950985	11	-	27760321	MV411	viability	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.45621019324224543	[674,525]	[666,348]	3	hSpCas9	negative selection	4552732
104950981	104951003	11	-	27760321	MV411	viability	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.2559482185051706	[263,207]	[145,242]	1	hSpCas9	negative selection	4552733
104951002	104951024	11	+	27760321	MV411	viability	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.1826087528778978	[908,745]	[346,1021]	1	hSpCas9	negative selection	4552734
104951991	104952013	11	-	27760321	MV411	viability	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.14278050167923018	[442,344]	[358,173]	1	hSpCas9	negative selection	4552735
104948665	104948687	11	-	27760321	HL60	viability	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.34901520193890073	[642,550]	[660,574]	4	hSpCas9	negative selection	4636194
104950963	104950985	11	-	27760321	HL60	viability	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.32338320435412027	[674,525]	[660,554]	4	hSpCas9	negative selection	4636195
104950981	104951003	11	-	27760321	HL60	viability	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.3400878401408285	[263,207]	[240,243]	4	hSpCas9	negative selection	4636196
104951002	104951024	11	+	27760321	HL60	viability	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.2462291343946338	[908,745]	[877,712]	3	hSpCas9	negative selection	4636197
104951991	104952013	11	-	27760321	HL60	viability	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	-0.05237386554594589	[442,344]	[265,352]	0	hSpCas9	negative selection	4636198
104948665	104948687	11	-	27760321	HT1080	viability	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	-0.3809636348445853	[550,429]	[108,194]	-2	hSpCas9	negative selection	4719657
104950963	104950985	11	-	27760321	HT1080	viability	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	-1.4292704432202248	[525,410]	[1,142]	-5	hSpCas9	negative selection	4719658
104950981	104951003	11	-	27760321	HT1080	viability	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.8648538693048011	[207,162]	[136,131]	5	hSpCas9	negative selection	4719659
104951002	104951024	11	+	27760321	HT1080	viability	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	1.1274596146950275	[745,581]	[564,591]	6	hSpCas9	negative selection	4719660
104951991	104952013	11	-	27760321	HT1080	viability	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.49166398421790447	[344,268]	[54,299]	2	hSpCas9	negative selection	4719661
104948665	104948687	11	-	27760321	HT29	viability after 7 days	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.16564239120106644	[550,429]	[969,718,476]	2	hSpCas9	negative selection	4803120
104950963	104950985	11	-	27760321	HT29	viability after 7 days	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.3806186985028434	[525,410]	[849,1011,507]	6	hSpCas9	negative selection	4803121
104950981	104951003	11	-	27760321	HT29	viability after 7 days	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.16099897531802265	[207,162]	[277,116,401]	2	hSpCas9	negative selection	4803122
104951002	104951024	11	+	27760321	HT29	viability after 7 days	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.34973502300046677	[745,581]	[1136,1168,966]	5	hSpCas9	negative selection	4803123
104951991	104952013	11	-	27760321	HT29	viability after 7 days	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.7047141663026502	[344,268]	[886,412,662]	9	hSpCas9	negative selection	4803124
104948665	104948687	11	-	27760321	HT29	viability after 25 days	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.19576406770202165	[550,429]	[640,651,630]	2	hSpCas9	negative selection	4886583
104950963	104950985	11	-	27760321	HT29	viability after 25 days	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.5128496718155713	[525,410]	[703,685,920]	5	hSpCas9	negative selection	4886584
104950981	104951003	11	-	27760321	HT29	viability after 25 days	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.2857823607496186	[207,162]	[200,247,337]	3	hSpCas9	negative selection	4886585
104951002	104951024	11	+	27760321	HT29	viability after 25 days	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.8639869093789838	[745,581]	[1274,1145,1766]	8	hSpCas9	negative selection	4886586
104951991	104952013	11	-	27760321	HT29	viability after 25 days	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	1.0423736085011877	[344,268]	[932,405,824]	9	hSpCas9	negative selection	4886587
104948665	104948687	11	-	27760321	HT29	viability after 22 days	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.39699760056543626	[550,429]	[613,937,690]	4	hSpCas9	negative selection	4970046
104950963	104950985	11	-	27760321	HT29	viability after 22 days	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.5581663837531041	[525,410]	[753,915,722]	6	hSpCas9	negative selection	4970047
104950981	104951003	11	-	27760321	HT29	viability after 22 days	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.1865664635996378	[207,162]	[242,282,205]	1	hSpCas9	negative selection	4970048
104951002	104951024	11	+	27760321	HT29	viability after 22 days	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.848195368991346	[745,581]	[1789,1120,1221]	8	hSpCas9	negative selection	4970049
104951991	104952013	11	-	27760321	HT29	viability after 22 days	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	1.1255021719200928	[344,268]	[990,546,778]	9	hSpCas9	negative selection	4970050
104948665	104948687	11	-	27760321	HT29	viability after 19 days	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.5313816251964354	[550,429]	[940,762,743]	5	hSpCas9	negative selection	5053509
104950963	104950985	11	-	27760321	HT29	viability after 19 days	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.36357281462892416	[525,410]	[932,917,258]	3	hSpCas9	negative selection	5053510
104950981	104951003	11	-	27760321	HT29	viability after 19 days	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	-0.24727688989222374	[207,162]	[321,151,80]	-2	hSpCas9	negative selection	5053511
104951002	104951024	11	+	27760321	HT29	viability after 19 days	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.552804172507938	[745,581]	[1193,1000,1152]	5	hSpCas9	negative selection	5053512
104951991	104952013	11	-	27760321	HT29	viability after 19 days	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.9992045074478633	[344,268]	[1100,566,486]	9	hSpCas9	negative selection	5053513
104948665	104948687	11	-	27760321	HT29	viability after 16 days	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.6589439148138967	[550,429]	[913,1086,596]	7	hSpCas9	negative selection	5136972
104950963	104950985	11	-	27760321	HT29	viability after 16 days	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.3666910125542601	[525,410]	[631,883,501]	4	hSpCas9	negative selection	5136973
104950981	104951003	11	-	27760321	HT29	viability after 16 days	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	-0.14080809838496178	[207,162]	[205,130,230]	-1	hSpCas9	negative selection	5136974
104951002	104951024	11	+	27760321	HT29	viability after 16 days	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.7719828760134155	[745,581]	[1497,1347,978]	8	hSpCas9	negative selection	5136975
104951991	104952013	11	-	27760321	HT29	viability after 16 days	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.4645634206036533	[344,268]	[614,283,540]	5	hSpCas9	negative selection	5136976
104948665	104948687	11	-	27760321	HT29	viability after 13 days	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.6958688717178512	[550,429]	[1189,951,639]	8	hSpCas9	negative selection	5220435
104950963	104950985	11	-	27760321	HT29	viability after 13 days	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.4757401019389598	[525,410]	[639,858,767]	6	hSpCas9	negative selection	5220436
104950981	104951003	11	-	27760321	HT29	viability after 13 days	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.13368692385782488	[207,162]	[306,228,175]	1	hSpCas9	negative selection	5220437
104951002	104951024	11	+	27760321	HT29	viability after 13 days	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.8561441104068577	[745,581]	[1637,1178,1366]	9	hSpCas9	negative selection	5220438
104951991	104952013	11	-	27760321	HT29	viability after 13 days	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.5698108639312749	[344,268]	[802,353,433]	7	hSpCas9	negative selection	5220439
104948665	104948687	11	-	27760321	HT29	viability after 10 days	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.34434813357077837	[550,429]	[1002,748,583]	4	hSpCas9	negative selection	5303898
104950963	104950985	11	-	27760321	HT29	viability after 10 days	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.38841424655269025	[525,410]	[729,900,671]	5	hSpCas9	negative selection	5303899
104950981	104951003	11	-	27760321	HT29	viability after 10 days	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	-0.40610955737378784	[207,162]	[191,137,192]	-5	hSpCas9	negative selection	5303900
104951002	104951024	11	+	27760321	HT29	viability after 10 days	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.6163296659694331	[745,581]	[1354,964,1478]	8	hSpCas9	negative selection	5303901
104951991	104952013	11	-	27760321	HT29	viability after 10 days	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.6183243602524823	[344,268]	[606,358,787]	8	hSpCas9	negative selection	5303902
104948665	104948687	11	-	27760321	MOLM13	viability	GTCTCCATAGCAAACCGTGGGG	CASP4	ENSG00000196954	0.1801576827712747	[642,550]	[501,276]	1	hSpCas9	negative selection	5387361
104950963	104950985	11	-	27760321	MOLM13	viability	AAGGAGCTACTTGAGGGTCTGG	CASP4	ENSG00000196954	0.6157798407759862	[674,525]	[621,424]	4	hSpCas9	negative selection	5387362
104950981	104951003	11	-	27760321	MOLM13	viability	TTTGACATCACAGGGATGAAGG	CASP4	ENSG00000196954	0.8261758449079479	[263,207]	[206,257]	6	hSpCas9	negative selection	5387363
104951002	104951024	11	+	27760321	MOLM13	viability	AGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.8416681667892058	[908,745]	[1058,639]	6	hSpCas9	negative selection	5387364
104951991	104952013	11	-	27760321	MOLM13	viability	CCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	-0.23919553012890082	[442,344]	[300,89]	-2	hSpCas9	negative selection	5387365
104954454	104954477	11	+	27661255	K562	viability	GGTCACAGGTGACAGAATCTAGG	CASP4	ENSG00000196954	0.2483436617428758	[238,361]	[329,242]	8	dCas9-KRAB	negative selection	5468210
104968152	104968175	11	+	27661255	K562	viability	GCGAAAAAGGTTTGTGATCTGGG	CASP4	ENSG00000196954	-0.028505712143415386	[761,701]	[558,586]	-1	dCas9-KRAB	negative selection	5468211
104968343	104968366	11	-	27661255	K562	viability	GGTGTTAGAGATATTGACGGAGG	CASP4	ENSG00000196954	0.23202913311432358	[721,970]	[945,656]	7	dCas9-KRAB	negative selection	5468212
104944382	104944405	11	+	27661255	K562	viability	GTGTGTGTGTGTGTAAGAAAGGG	CASP4	ENSG00000196954	-0.020068994186342753	[913,924]	[768,685]	-1	dCas9-KRAB	negative selection	5479311
104951991	104952014	11	-	27260156	BXPC3	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.2221289787075338	[1072]	[1263,1092,1218,1715]	5	hSpCas9	negative selection	5533472
104951059	104951082	11	-	27260156	BXPC3	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.06631141049954375	[584]	[559,577,731,709]	1	hSpCas9	negative selection	5533473
104954807	104954830	11	-	27260156	BXPC3	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.06115112362385877	[235]	[242,216,306,266]	1	hSpCas9	negative selection	5533474
104951015	104951038	11	-	27260156	BXPC3	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.23760476263095565	[783]	[888,950,982,1056]	5	hSpCas9	negative selection	5597750
104949757	104949780	11	-	27260156	BXPC3	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.3961022707439432	[122]	[70,87,91,148]	-7	hSpCas9	negative selection	5597751
104949582	104949605	11	-	27260156	BXPC3	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.6072792979507657	[391]	[597,472,700,749]	9	hSpCas9	negative selection	5597752
104951991	104952014	11	-	27260156	A673	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.18087821673129878	[1072]	[1474,1442,1390,1536]	4	hSpCas9	negative selection	5654723
104951059	104951082	11	-	27260156	A673	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.063697806134354	[584]	[818,657,747,720]	1	hSpCas9	negative selection	5654724
104954807	104954830	11	-	27260156	A673	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.07458718133386211	[235]	[280,147,298,356]	-2	hSpCas9	negative selection	5654725
104951015	104951038	11	-	27260156	A673	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.12258538937317887	[783]	[1161,961,971,1018]	3	hSpCas9	negative selection	5719001
104949757	104949780	11	-	27260156	A673	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.00759899016825627	[122]	[173,181,117,113]	0	hSpCas9	negative selection	5719002
104949582	104949605	11	-	27260156	A673	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.19714019768356106	[391]	[526,534,566,525]	5	hSpCas9	negative selection	5719003
104951991	104952014	11	-	27260156	A375	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.18654554119406952	[1072]	[1193,1486,1735,1303]	2	hSpCas9	negative selection	5775974
104951059	104951082	11	-	27260156	A375	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.22945606359056453	[584]	[631,1018,840,744]	3	hSpCas9	negative selection	5775975
104954807	104954830	11	-	27260156	A375	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.22762779484683615	[235]	[181,214,281,255]	-3	hSpCas9	negative selection	5775976
104951015	104951038	11	-	27260156	A375	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.49943525102857456	[783]	[1373,1535,1158,1154]	7	hSpCas9	negative selection	5840252
104949757	104949780	11	-	27260156	A375	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.1780177223119488	[122]	[103,138,232,168]	2	hSpCas9	negative selection	5840253
104949582	104949605	11	-	27260156	A375	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.4081458383125879	[391]	[548,607,722,553]	6	hSpCas9	negative selection	5840254
104951991	104952014	11	-	27260156	COLO741	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.2699749607642472	[1072]	[1791,1645,1537]	5	hSpCas9	negative selection	5897225
104951059	104951082	11	-	27260156	COLO741	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.13755660448042056	[584]	[1018,860,616]	3	hSpCas9	negative selection	5897226
104954807	104954830	11	-	27260156	COLO741	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.39451734875853595	[235]	[342,446,393]	7	hSpCas9	negative selection	5897227
104951015	104951038	11	-	27260156	COLO741	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.46086493766943903	[783]	[1726,1335,1118]	8	hSpCas9	negative selection	5961503
104949757	104949780	11	-	27260156	COLO741	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.04953131519607412	[122]	[150,191,114]	-1	hSpCas9	negative selection	5961504
104949582	104949605	11	-	27260156	COLO741	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.3428631090683687	[391]	[599,730,574]	7	hSpCas9	negative selection	5961505
104951991	104952014	11	-	27260156	CAL120	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	-0.04285174906704459	[1072]	[1322,1498,1073]	0	hSpCas9	negative selection	6018476
104951059	104951082	11	-	27260156	CAL120	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	-0.5037772806288646	[584]	[537,564,441]	-6	hSpCas9	negative selection	6018477
104954807	104954830	11	-	27260156	CAL120	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.22691124385968653	[235]	[79,452,194]	-3	hSpCas9	negative selection	6018478
104951015	104951038	11	-	27260156	CAL120	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.3630283469076575	[783]	[1110,1483,1148]	5	hSpCas9	negative selection	6082754
104949757	104949780	11	-	27260156	CAL120	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.03617666087364202	[122]	[410,52,46]	0	hSpCas9	negative selection	6082755
104949582	104949605	11	-	27260156	CAL120	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.28686735855983575	[391]	[635,546,607]	4	hSpCas9	negative selection	6082756
104951991	104952014	11	-	27260156	CADOES1	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.28153731477342436	[1072]	[978,1337,1343,1190]	5	hSpCas9	negative selection	6139727
104951059	104951082	11	-	27260156	CADOES1	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.6441129269122514	[584]	[931,546,1178,737]	9	hSpCas9	negative selection	6139728
104954807	104954830	11	-	27260156	CADOES1	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.15557553395177126	[235]	[120,153,221,294]	-3	hSpCas9	negative selection	6139729
104951015	104951038	11	-	27260156	CADOES1	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.20008492416257062	[783]	[786,780,856,928]	3	hSpCas9	negative selection	6204005
104949757	104949780	11	-	27260156	CADOES1	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.05352068640208052	[122]	[147,96,155,71]	0	hSpCas9	negative selection	6204006
104949582	104949605	11	-	27260156	CADOES1	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.3295773406250733	[391]	[496,407,402,526]	5	hSpCas9	negative selection	6204007
104951991	104952014	11	-	27260156	EWS502	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.38128569986741234	[1072]	[1119,1466,1648,1744]	6	hSpCas9	negative selection	6260978
104951059	104951082	11	-	27260156	EWS502	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.15805454970118937	[584]	[723,513,630,911]	2	hSpCas9	negative selection	6260979
104954807	104954830	11	-	27260156	EWS502	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.030974643463362206	[235]	[178,329,292,222]	0	hSpCas9	negative selection	6260980
104951015	104951038	11	-	27260156	EWS502	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.32307500016083235	[783]	[1061,887,1060,1151]	5	hSpCas9	negative selection	6325256
104949757	104949780	11	-	27260156	EWS502	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.8204475143719105	[122]	[76,55,77,84]	-8	hSpCas9	negative selection	6325257
104949582	104949605	11	-	27260156	EWS502	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.3572344902490564	[391]	[417,568,585,567]	6	hSpCas9	negative selection	6325258
104951991	104952014	11	-	27260156	EW8	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.38036566552457596	[1072]	[2034,776,774,1095]	7	hSpCas9	negative selection	6382229
104951059	104951082	11	-	27260156	EW8	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.12880383024009673	[584]	[680,512,399,515]	2	hSpCas9	negative selection	6382230
104954807	104954830	11	-	27260156	EW8	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.13450771473001422	[235]	[249,150,118,193]	-3	hSpCas9	negative selection	6382231
104951015	104951038	11	-	27260156	EW8	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.0766839739616686	[783]	[828,708,534,645]	1	hSpCas9	negative selection	6446507
104949757	104949780	11	-	27260156	EW8	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.021515995555044354	[122]	[103,133,70,88]	0	hSpCas9	negative selection	6446508
104949582	104949605	11	-	27260156	EW8	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.29948743802238215	[391]	[388,408,388,375]	5	hSpCas9	negative selection	6446509
104951991	104952014	11	-	27260156	CORL105	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.2083338520171918	[1072]	[1376,1422,1574,1446]	4	hSpCas9	negative selection	6503480
104951059	104951082	11	-	27260156	CORL105	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.7047790287699336	[584]	[1236,917,1020,1280]	9	hSpCas9	negative selection	6503481
104954807	104954830	11	-	27260156	CORL105	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.017589143320025702	[235]	[416,165,298,220]	0	hSpCas9	negative selection	6503482
104951015	104951038	11	-	27260156	CORL105	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.4149804914179155	[783]	[1129,1118,1439,1237]	7	hSpCas9	negative selection	6567758
104949757	104949780	11	-	27260156	CORL105	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.52129613923546	[122]	[111,65,104,119]	-7	hSpCas9	negative selection	6567759
104949582	104949605	11	-	27260156	CORL105	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.4425741459132809	[391]	[564,721,681,530]	7	hSpCas9	negative selection	6567760
104951991	104952014	11	-	27260156	HS294T	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.11219363585374964	[1072]	[554,343,434,451]	1	hSpCas9	negative selection	6624731
104951059	104951082	11	-	27260156	HS294T	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.3088698480230537	[584]	[215,213,284,439]	4	hSpCas9	negative selection	6624732
104954807	104954830	11	-	27260156	HS294T	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	1.1578950075681549	[235]	[392,101,93,210]	9	hSpCas9	negative selection	6624733
104951015	104951038	11	-	27260156	HS294T	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.023965947312863056	[783]	[277,304,342,308]	0	hSpCas9	negative selection	6689009
104949757	104949780	11	-	27260156	HS294T	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.17510905873242488	[122]	[37,29,89,59]	2	hSpCas9	negative selection	6689010
104949582	104949605	11	-	27260156	HS294T	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.6718573893127442	[391]	[181,229,303,257]	8	hSpCas9	negative selection	6689011
104951991	104952014	11	-	27260156	HCC44	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.34659753623292144	[1072]	[1426,1564,1694,1486]	5	hSpCas9	negative selection	6745982
104951059	104951082	11	-	27260156	HCC44	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.17559072994258812	[584]	[813,765,901,537]	3	hSpCas9	negative selection	6745983
104954807	104954830	11	-	27260156	HCC44	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.07183895356266534	[235]	[401,239,240,247]	1	hSpCas9	negative selection	6745984
104951015	104951038	11	-	27260156	HCC44	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.51483468471385	[783]	[1289,1312,1494,1002]	8	hSpCas9	negative selection	6810260
104949757	104949780	11	-	27260156	HCC44	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.22905630008488975	[122]	[64,157,157,89]	-4	hSpCas9	negative selection	6810261
104949582	104949605	11	-	27260156	HCC44	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.1367888776590623	[391]	[638,492,649,213]	2	hSpCas9	negative selection	6810262
104951991	104952014	11	-	27260156	G402	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.6327376014901309	[1072]	[2205,2689,1969,1343]	7	hSpCas9	negative selection	6867233
104951059	104951082	11	-	27260156	G402	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	-0.18901945704624398	[584]	[760,465,735,552]	-2	hSpCas9	negative selection	6867234
104954807	104954830	11	-	27260156	G402	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.11746204021559958	[235]	[216,543,321,171]	1	hSpCas9	negative selection	6867235
104951015	104951038	11	-	27260156	G402	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.24465297753858728	[783]	[1205,1092,819,1404]	3	hSpCas9	negative selection	6931511
104949757	104949780	11	-	27260156	G402	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.06189043627874247	[122]	[129,177,85,225]	0	hSpCas9	negative selection	6931512
104949582	104949605	11	-	27260156	G402	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.5858059723107205	[391]	[974,554,659,706]	7	hSpCas9	negative selection	6931513
104951991	104952014	11	-	27260156	L33	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.008057229147010903	[1072]	[1151,409,622,1168]	0	hSpCas9	negative selection	6988484
104951059	104951082	11	-	27260156	L33	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.5660345029772962	[584]	[922,278,705,737]	9	hSpCas9	negative selection	6988485
104954807	104954830	11	-	27260156	L33	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.07546725090087913	[235]	[234,98,168,150]	-2	hSpCas9	negative selection	6988486
104951015	104951038	11	-	27260156	L33	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.16726341577521464	[783]	[952,393,576,688]	3	hSpCas9	negative selection	7052762
104949757	104949780	11	-	27260156	L33	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.3313984485555823	[122]	[160,75,102,108]	7	hSpCas9	negative selection	7052763
104949582	104949605	11	-	27260156	L33	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.34629731112130413	[391]	[477,221,323,458]	7	hSpCas9	negative selection	7052764
104951991	104952014	11	-	27260156	K562	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.7098733549515781	[1072]	[1435,1698,1435,1639]	8	hSpCas9	negative selection	7109735
104951059	104951082	11	-	27260156	K562	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.5766473801638319	[584]	[464,955,845,806]	7	hSpCas9	negative selection	7109736
104954807	104954830	11	-	27260156	K562	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.635016184431404	[235]	[167,681,144,311]	7	hSpCas9	negative selection	7109737
104951015	104951038	11	-	27260156	K562	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.44666185590270546	[783]	[1383,770,615,1033]	5	hSpCas9	negative selection	7174013
104949757	104949780	11	-	27260156	K562	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.14172559932979767	[122]	[85,187,78,127]	1	hSpCas9	negative selection	7174014
104949582	104949605	11	-	27260156	K562	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.4052552469103361	[391]	[398,442,363,610]	5	hSpCas9	negative selection	7174015
104951991	104952014	11	-	27260156	HT29	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.27822470665866406	[1072]	[1651,1624,1656,1411]	5	hSpCas9	negative selection	7230986
104951059	104951082	11	-	27260156	HT29	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.3990546232068722	[584]	[916,1212,867,786]	7	hSpCas9	negative selection	7230987
104954807	104954830	11	-	27260156	HT29	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.08464865666669885	[235]	[307,373,175,237]	-2	hSpCas9	negative selection	7230988
104951015	104951038	11	-	27260156	HT29	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.3332447641735329	[783]	[1423,1306,1056,1050]	6	hSpCas9	negative selection	7295264
104949757	104949780	11	-	27260156	HT29	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.22796946883746827	[122]	[146,107,157,99]	-4	hSpCas9	negative selection	7295265
104949582	104949605	11	-	27260156	HT29	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.4055033833345147	[391]	[672,750,544,571]	7	hSpCas9	negative selection	7295266
104951991	104952014	11	-	27260156	MHHES1	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.2815996520660473	[1072]	[1701,1603,1333,1285]	5	hSpCas9	negative selection	7352237
104951059	104951082	11	-	27260156	MHHES1	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.4866316754668178	[584]	[1142,1039,932,656]	8	hSpCas9	negative selection	7352238
104954807	104954830	11	-	27260156	MHHES1	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.37692417763499964	[235]	[272,222,190,149]	-6	hSpCas9	negative selection	7352239
104951015	104951038	11	-	27260156	MHHES1	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.012557085648207233	[783]	[1081,789,1027,700]	0	hSpCas9	negative selection	7416515
104949757	104949780	11	-	27260156	MHHES1	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.47714836772087077	[122]	[61,84,112,123]	-7	hSpCas9	negative selection	7416516
104949582	104949605	11	-	27260156	MHHES1	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	-0.03617965104325771	[391]	[521,518,415,304]	0	hSpCas9	negative selection	7416517
104951991	104952014	11	-	27260156	MEWO	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.0111183239611361	[1072]	[1202,954,913]	0	hSpCas9	negative selection	7473488
104951059	104951082	11	-	27260156	MEWO	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.5059950059414318	[584]	[739,837,745]	8	hSpCas9	negative selection	7473489
104954807	104954830	11	-	27260156	MEWO	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.11564583200590328	[235]	[255,209,254]	2	hSpCas9	negative selection	7473490
104951015	104951038	11	-	27260156	MEWO	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.3228489047224695	[783]	[949,796,1011]	7	hSpCas9	negative selection	7537766
104949757	104949780	11	-	27260156	MEWO	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.40467384967154096	[122]	[91,34,134]	-7	hSpCas9	negative selection	7537767
104949582	104949605	11	-	27260156	MEWO	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.38354288757326754	[391]	[610,449,399]	7	hSpCas9	negative selection	7537768
104951991	104952014	11	-	27260156	LNCAPCLONEFGC	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.3514284447272431	[1072]	[1396,1023,1450,1129]	5	hSpCas9	negative selection	7594739
104951059	104951082	11	-	27260156	LNCAPCLONEFGC	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.19188185597690638	[584]	[596,447,723,679]	3	hSpCas9	negative selection	7594740
104954807	104954830	11	-	27260156	LNCAPCLONEFGC	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.19618788319428093	[235]	[254,179,388,180]	3	hSpCas9	negative selection	7594741
104951015	104951038	11	-	27260156	LNCAPCLONEFGC	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.4277859277020871	[783]	[1020,1104,904,770]	6	hSpCas9	negative selection	7659017
104949757	104949780	11	-	27260156	LNCAPCLONEFGC	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.553024364672376	[122]	[66,64,91,82]	-7	hSpCas9	negative selection	7659018
104949582	104949605	11	-	27260156	LNCAPCLONEFGC	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.4549135772155446	[391]	[532,401,504,513]	7	hSpCas9	negative selection	7659019
104951991	104952014	11	-	27260156	PANC0327	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.30728897239646535	[1072]	[1084,980,1192,1475]	4	hSpCas9	negative selection	7715990
104951059	104951082	11	-	27260156	PANC0327	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.736439442536279	[584]	[1080,587,1158,688]	9	hSpCas9	negative selection	7715991
104954807	104954830	11	-	27260156	PANC0327	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.11886880232846164	[235]	[335,206,107,130]	-2	hSpCas9	negative selection	7715992
104951015	104951038	11	-	27260156	PANC0327	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.2586878108744567	[783]	[923,579,1014,853]	4	hSpCas9	negative selection	7780268
104949757	104949780	11	-	27260156	PANC0327	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.21876063929829437	[122]	[43,52,239,39]	-3	hSpCas9	negative selection	7780269
104949582	104949605	11	-	27260156	PANC0327	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.2874070118971175	[391]	[607,327,274,515]	4	hSpCas9	negative selection	7780270
104951991	104952014	11	-	27260156	NCIH2009	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.36248847156969033	[1072]	[2245,1861,1734]	5	hSpCas9	negative selection	7837241
104951059	104951082	11	-	27260156	NCIH2009	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.7002604131215231	[584]	[1394,1052,1551]	8	hSpCas9	negative selection	7837242
104954807	104954830	11	-	27260156	NCIH2009	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.2911967534814168	[235]	[525,345,362]	4	hSpCas9	negative selection	7837243
104951015	104951038	11	-	27260156	NCIH2009	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.4406241953610054	[783]	[1845,1342,1341]	6	hSpCas9	negative selection	7901519
104949757	104949780	11	-	27260156	NCIH2009	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.10080445270207727	[122]	[185,122,244]	1	hSpCas9	negative selection	7901520
104949582	104949605	11	-	27260156	NCIH2009	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.38717122534361015	[391]	[900,502,783]	5	hSpCas9	negative selection	7901521
104951991	104952014	11	-	27260156	NCIH1373	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.5256452555169047	[1072]	[2163,1451,1366,540]	5	hSpCas9	negative selection	7958492
104951059	104951082	11	-	27260156	NCIH1373	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.6934935398857571	[584]	[1049,706,955,418]	7	hSpCas9	negative selection	7958493
104954807	104954830	11	-	27260156	NCIH1373	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.19585454355349485	[235]	[399,159,130,70]	-2	hSpCas9	negative selection	7958494
104951015	104951038	11	-	27260156	NCIH1373	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.6653756512788928	[783]	[1536,1397,1480,303]	6	hSpCas9	negative selection	8022770
104949757	104949780	11	-	27260156	NCIH1373	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.6816671528250788	[122]	[144,41,82,22]	-6	hSpCas9	negative selection	8022771
104949582	104949605	11	-	27260156	NCIH1373	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.8665043402813213	[391]	[1223,438,453,320]	8	hSpCas9	negative selection	8022772
104951991	104952014	11	-	27260156	PATU8902	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.6582483608178442	[1072]	[2548,2507,2126,2278]	7	hSpCas9	negative selection	8079743
104951059	104951082	11	-	27260156	PATU8902	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.18620145589754938	[584]	[1120,848,753,1030]	2	hSpCas9	negative selection	8079744
104954807	104954830	11	-	27260156	PATU8902	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.31570400536087684	[235]	[197,185,245,451]	-3	hSpCas9	negative selection	8079745
104951015	104951038	11	-	27260156	PATU8902	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.2904131181568014	[783]	[960,1587,790,2246]	3	hSpCas9	negative selection	8144021
104949757	104949780	11	-	27260156	PATU8902	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.9360681745099662	[122]	[70,58,68,173]	-7	hSpCas9	negative selection	8144022
104949582	104949605	11	-	27260156	PATU8902	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.43228610129100165	[391]	[763,445,952,717]	4	hSpCas9	negative selection	8144023
104951991	104952014	11	-	27260156	PANC1	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.4621938907279892	[1072]	[1512,1511,1148,975]	7	hSpCas9	negative selection	8200994
104951059	104951082	11	-	27260156	PANC1	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.1737590932981768	[584]	[410,705,553,610]	2	hSpCas9	negative selection	8200995
104954807	104954830	11	-	27260156	PANC1	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.18526754027305503	[235]	[149,284,183,122]	-3	hSpCas9	negative selection	8200996
104951015	104951038	11	-	27260156	PANC1	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.5309122276893873	[783]	[1035,993,1036,834]	8	hSpCas9	negative selection	8265272
104949757	104949780	11	-	27260156	PANC1	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.42770167498520406	[122]	[114,116,135,185]	7	hSpCas9	negative selection	8265273
104949582	104949605	11	-	27260156	PANC1	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.37437500419025815	[391]	[367,405,560,404]	6	hSpCas9	negative selection	8265274
104951991	104952014	11	-	27260156	PANC0813	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.09803430556464554	[1072]	[1406,1156,1624,1218]	1	hSpCas9	negative selection	8322245
104951059	104951082	11	-	27260156	PANC0813	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.49012765563232036	[584]	[1194,755,784,1133]	7	hSpCas9	negative selection	8322246
104954807	104954830	11	-	27260156	PANC0813	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.0670725043424063	[235]	[270,253,188,339]	-1	hSpCas9	negative selection	8322247
104951015	104951038	11	-	27260156	PANC0813	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.3957439033829152	[783]	[1373,1337,1141,1015]	6	hSpCas9	negative selection	8386523
104949757	104949780	11	-	27260156	PANC0813	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.4910506273472808	[122]	[350,154,146,173]	7	hSpCas9	negative selection	8386524
104949582	104949605	11	-	27260156	PANC0813	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.40012552756902087	[391]	[532,682,606,599]	6	hSpCas9	negative selection	8386525
104951991	104952014	11	-	27260156	RDES	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.3779320597574618	[1072]	[1260,1574,1778,1875]	6	hSpCas9	negative selection	8443496
104951059	104951082	11	-	27260156	RDES	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.09453607329961133	[584]	[731,643,679,808]	1	hSpCas9	negative selection	8443497
104954807	104954830	11	-	27260156	RDES	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.2301521985140269	[235]	[161,241,288,243]	-4	hSpCas9	negative selection	8443498
104951015	104951038	11	-	27260156	RDES	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.1427331494587748	[783]	[682,856,1170,1391]	2	hSpCas9	negative selection	8507774
104949757	104949780	11	-	27260156	RDES	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.24914135099791768	[122]	[127,109,94,139]	-4	hSpCas9	negative selection	8507775
104949582	104949605	11	-	27260156	RDES	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.4165980000822627	[391]	[551,467,715,693]	6	hSpCas9	negative selection	8507776
104951991	104952014	11	-	27260156	PC3	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.03766491132550143	[1072]	[720,1032,1748,1203]	0	hSpCas9	negative selection	8564747
104951059	104951082	11	-	27260156	PC3	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.08278218051680031	[584]	[403,656,1109,514]	1	hSpCas9	negative selection	8564748
104954807	104954830	11	-	27260156	PC3	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.022081340876500155	[235]	[172,296,281,186]	0	hSpCas9	negative selection	8564749
104951015	104951038	11	-	27260156	PC3	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.35997912946598387	[783]	[581,1112,1669,991]	7	hSpCas9	negative selection	8629025
104949757	104949780	11	-	27260156	PC3	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.44929825239549936	[122]	[73,82,130,82]	-8	hSpCas9	negative selection	8629026
104949582	104949605	11	-	27260156	PC3	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.004024387255072148	[391]	[311,445,421,381]	0	hSpCas9	negative selection	8629027
104951991	104952014	11	-	27260156	PATU8988T	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.2922357884424067	[1072]	[1103,1463,1128,1412]	5	hSpCas9	negative selection	8685998
104951059	104951082	11	-	27260156	PATU8988T	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.25326490150714404	[584]	[601,578,964,523]	4	hSpCas9	negative selection	8685999
104954807	104954830	11	-	27260156	PATU8988T	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.016943594890704516	[235]	[242,170,210,297]	0	hSpCas9	negative selection	8686000
104951015	104951038	11	-	27260156	PATU8988T	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.39101884951081856	[783]	[920,990,1137,914]	6	hSpCas9	negative selection	8750276
104949757	104949780	11	-	27260156	PATU8988T	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-1.5532614336210546	[122]	[43,33,55,25]	-9	hSpCas9	negative selection	8750277
104949582	104949605	11	-	27260156	PATU8988T	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.5415279953136507	[391]	[499,508,600,593]	8	hSpCas9	negative selection	8750278
104951991	104952014	11	-	27260156	T47D	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.34178044289668086	[1072]	[1691,1494,1544,1613]	7	hSpCas9	negative selection	8807249
104951059	104951082	11	-	27260156	T47D	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.1525241640040353	[584]	[778,684,799,771]	3	hSpCas9	negative selection	8807250
104954807	104954830	11	-	27260156	T47D	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.5718344577114063	[235]	[193,197,203,140]	-8	hSpCas9	negative selection	8807251
104951015	104951038	11	-	27260156	T47D	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.21223658498035414	[783]	[1071,834,1160,1185]	4	hSpCas9	negative selection	8871527
104949757	104949780	11	-	27260156	T47D	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.07127777387443013	[122]	[145,94,162,144]	-1	hSpCas9	negative selection	8871528
104949582	104949605	11	-	27260156	T47D	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.3352167972170904	[391]	[629,562,542,569]	7	hSpCas9	negative selection	8871529
104951991	104952014	11	-	27260156	SU8686	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.1676134840245289	[1072]	[1279,970,1187,1380]	3	hSpCas9	negative selection	8928500
104951059	104951082	11	-	27260156	SU8686	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.480667990758383	[584]	[806,791,726,923]	7	hSpCas9	negative selection	8928501
104954807	104954830	11	-	27260156	SU8686	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.014620481794959561	[235]	[207,177,274,282]	0	hSpCas9	negative selection	8928502
104951015	104951038	11	-	27260156	SU8686	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.4856235145150577	[783]	[880,912,1178,1485]	7	hSpCas9	negative selection	8992778
104949757	104949780	11	-	27260156	SU8686	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.10522170252638396	[122]	[71,136,124,121]	-2	hSpCas9	negative selection	8992779
104949582	104949605	11	-	27260156	SU8686	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.42596896330153533	[391]	[424,412,603,698]	7	hSpCas9	negative selection	8992780
104951991	104952014	11	-	27260156	SKES1	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.058517986877719474	[1072]	[1488,1015,1170,842]	1	hSpCas9	negative selection	9049751
104951059	104951082	11	-	27260156	SKES1	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.25725920652114614	[584]	[708,634,775,659]	5	hSpCas9	negative selection	9049752
104954807	104954830	11	-	27260156	SKES1	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	0.1736698646665651	[235]	[183,243,264,342]	4	hSpCas9	negative selection	9049753
104951015	104951038	11	-	27260156	SKES1	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.46282766107327655	[783]	[1222,1299,913,929]	8	hSpCas9	negative selection	9114029
104949757	104949780	11	-	27260156	SKES1	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.2628545873259658	[122]	[223,70,127,163]	5	hSpCas9	negative selection	9114030
104949582	104949605	11	-	27260156	SKES1	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.016267646987335765	[391]	[446,480,379,298]	0	hSpCas9	negative selection	9114031
104951991	104952014	11	-	27260156	TOV112D	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.4033869472975502	[1072]	[1974,1563,1028,1202]	7	hSpCas9	negative selection	9171002
104951059	104951082	11	-	27260156	TOV112D	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.21373613952446252	[584]	[737,798,639,576]	4	hSpCas9	negative selection	9171003
104954807	104954830	11	-	27260156	TOV112D	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.2769661975205131	[235]	[290,298,113,111]	-5	hSpCas9	negative selection	9171004
104951015	104951038	11	-	27260156	TOV112D	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.2974095321754796	[783]	[981,1328,769,870]	5	hSpCas9	negative selection	9235280
104949757	104949780	11	-	27260156	TOV112D	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.5078255654741182	[122]	[125,89,27,105]	-7	hSpCas9	negative selection	9235281
104949582	104949605	11	-	27260156	TOV112D	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.16774723380315926	[391]	[450,572,343,428]	3	hSpCas9	negative selection	9235282
104951991	104952014	11	-	27260156	TC71	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.2782455319190986	[1072]	[1507,1312,1300,1461]	6	hSpCas9	negative selection	9292253
104951059	104951082	11	-	27260156	TC71	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.12453569875152981	[584]	[577,684,740,733]	3	hSpCas9	negative selection	9292254
104954807	104954830	11	-	27260156	TC71	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.17321460049667303	[235]	[211,241,207,236]	-4	hSpCas9	negative selection	9292255
104951015	104951038	11	-	27260156	TC71	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.36960214567568495	[783]	[883,1120,1073,1280]	8	hSpCas9	negative selection	9356531
104949757	104949780	11	-	27260156	TC71	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.10422679287812153	[122]	[127,77,192,86]	-3	hSpCas9	negative selection	9356532
104949582	104949605	11	-	27260156	TC71	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.2719023926192255	[391]	[595,453,436,544]	6	hSpCas9	negative selection	9356533
104951991	104952014	11	-	27260156	TC32	viability	TCCTGCAGCTCATCCGAATATGG	CASP4	ENSG00000196954	0.29805287696779703	[1072]	[1088,1087,1589,1252]	5	hSpCas9	negative selection	9413504
104951059	104951082	11	-	27260156	TC32	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.2181769762384887	[584]	[520,457,784,879]	4	hSpCas9	negative selection	9413505
104954807	104954830	11	-	27260156	TC32	viability	TATGCAAGAGAAGCAACGTATGG	CASP4	ENSG00000196954	-0.41699974018026054	[235]	[147,140,216,168]	-7	hSpCas9	negative selection	9413506
104951015	104951038	11	-	27260156	TC32	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.1711999957943381	[783]	[888,598,954,931]	3	hSpCas9	negative selection	9477782
104949757	104949780	11	-	27260156	TC32	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.876133626431399	[122]	[52,0,120,111]	-9	hSpCas9	negative selection	9477783
104949582	104949605	11	-	27260156	TC32	viability	CCGCAACTGCCTCAGTCTGAAGG	CASP4	ENSG00000196954	0.25723569900524074	[391]	[333,400,558,491]	4	hSpCas9	negative selection	9477784
104950907	104950930	11	+	27869803	HPAFII	viability after 27 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.5722546212495703	[435]	[606,118,NaN]	4	hSpCas9	negative selection	9539502
104954939	104954962	11	+	27869803	HPAFII	viability after 27 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	0.05615179077961363	[157]	[87,84,NaN]	0	hSpCas9	negative selection	9539503
104950907	104950930	11	+	27869803	HPAFII	viability after 15 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.04310847472713153	[435]	[779,297,NaN]	0	hSpCas9	negative selection	9621951
104954939	104954962	11	+	27869803	HPAFII	viability after 15 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	0.08959609818865233	[157]	[221,154,NaN]	1	hSpCas9	negative selection	9621952
104950907	104950930	11	+	27869803	ASPC1	viability after 36 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.618455252215746	[1002]	[701,881,142]	6	hSpCas9	negative selection	9704400
104954939	104954962	11	+	27869803	ASPC1	viability after 36 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	1.0542002039984064	[455]	[37,340,523]	8	hSpCas9	negative selection	9704401
104950907	104950930	11	+	27869803	PATU8988S	viability after 35 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	1.4640052970807411	[728]	[799,819,NaN]	9	hSpCas9	negative selection	9786849
104954939	104954962	11	+	27869803	PATU8988S	viability after 35 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	0.09675925985507705	[359]	[175,133,NaN]	1	hSpCas9	negative selection	9786850
104950907	104950930	11	+	27869803	PATU8988S	viability after 31 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	1.1400354979648024	[728]	[582,713,NaN]	9	hSpCas9	negative selection	9869298
104954939	104954962	11	+	27869803	PATU8988S	viability after 31 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	0.24086490447617548	[359]	[122,228,NaN]	3	hSpCas9	negative selection	9869299
104950907	104950930	11	+	27869803	HPAFII	viability after 35 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.6924540486425879	[435]	[573,111,NaN]	4	hSpCas9	negative selection	9951747
104954939	104954962	11	+	27869803	HPAFII	viability after 35 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	0.22821800273901977	[157]	[72,116,NaN]	1	hSpCas9	negative selection	9951748
104950907	104950930	11	+	27869803	HPAFII	viability after 31 days	CGGCTGAGGGATTCTTACCCTGG	CASP4	ENSG00000196954	0.38527822926017796	[435]	[477,146,NaN]	2	hSpCas9	negative selection	10034196
104954939	104954962	11	+	27869803	HPAFII	viability after 31 days	CAGTGAGGAAATCTTTGCCCAGG	CASP4	ENSG00000196954	-0.5137222532528622	[157]	[30,95,NaN]	-3	hSpCas9	negative selection	10034197
104948667	104948690	11	-	28162770	P31FUJ	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.23130590143239177	[223]	[308]	2	hSpCas9	negative selection	10126205
104949666	104949689	11	+	28162770	P31FUJ	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.10352771074316047	[1534]	[1937]	1	hSpCas9	negative selection	10126206
104948596	104948619	11	-	28162770	P31FUJ	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.1799793209240972	[79]	[212]	9	hSpCas9	negative selection	10126207
104951015	104951038	11	-	28162770	P31FUJ	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.3287013234827887	[123]	[182]	3	hSpCas9	negative selection	10126208
104951001	104951024	11	+	28162770	P31FUJ	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.03911035276586794	[134]	[162]	0	hSpCas9	negative selection	10126209
104949757	104949780	11	-	28162770	P31FUJ	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.245660675006099	[88]	[123]	2	hSpCas9	negative selection	10126210
104951059	104951082	11	-	28162770	P31FUJ	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.07614803647477375	[267]	[331]	0	hSpCas9	negative selection	10126211
104948563	104948586	11	-	28162770	P31FUJ	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.7115838203746219	[475]	[915]	7	hSpCas9	negative selection	10126212
104950968	104950991	11	-	28162770	P31FUJ	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.01584366912855851	[227]	[264]	0	hSpCas9	negative selection	10126213
104949680	104949703	11	-	28162770	P31FUJ	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.016337759761034354	[312]	[371]	0	hSpCas9	negative selection	10126214
104948667	104948690	11	-	28162770	TF1	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	NaN	[NaN]	[220]	1	hSpCas9	negative selection	10295571
104949666	104949689	11	+	28162770	TF1	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	NaN	[NaN]	[1383]	1	hSpCas9	negative selection	10295572
104948596	104948619	11	-	28162770	TF1	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10295573
104951015	104951038	11	-	28162770	TF1	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10295574
104951001	104951024	11	+	28162770	TF1	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10295575
104949757	104949780	11	-	28162770	TF1	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10295576
104951059	104951082	11	-	28162770	TF1	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	NaN	[NaN]	[371]	1	hSpCas9	negative selection	10295577
104948563	104948586	11	-	28162770	TF1	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	NaN	[NaN]	[547]	1	hSpCas9	negative selection	10295578
104950968	104950991	11	-	28162770	TF1	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10295579
104949680	104949703	11	-	28162770	TF1	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	NaN	[NaN]	[435]	1	hSpCas9	negative selection	10295580
104948667	104948690	11	-	28162770	SKM1	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.8164000616606112	[52]	[164]	7	hSpCas9	negative selection	10464937
104949666	104949689	11	+	28162770	SKM1	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	-0.09740466128621783	[327]	[541]	-1	hSpCas9	negative selection	10464938
104948596	104948619	11	-	28162770	SKM1	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	0.9187554753065748	[37]	[126]	8	hSpCas9	negative selection	10464939
104951015	104951038	11	-	28162770	SKM1	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.5405683813627027	[34]	[89]	5	hSpCas9	negative selection	10464940
104951001	104951024	11	+	28162770	SKM1	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.23689199103156294	[35]	[74]	2	hSpCas9	negative selection	10464941
104949757	104949780	11	-	28162770	SKM1	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.3074285251922473	[27]	[39]	-3	hSpCas9	negative selection	10464942
104951059	104951082	11	-	28162770	SKM1	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	-0.023635559191656053	[68]	[119]	0	hSpCas9	negative selection	10464943
104948563	104948586	11	-	28162770	SKM1	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.04608662647241357	[102]	[187]	0	hSpCas9	negative selection	10464944
104950968	104950991	11	-	28162770	SKM1	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	0.608632656307857	[45]	[123]	6	hSpCas9	negative selection	10464945
104949680	104949703	11	-	28162770	SKM1	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	1.15888947903029	[56]	[224]	9	hSpCas9	negative selection	10464946
104948667	104948690	11	-	28162770	SKM1	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.8164000616606112	[52]	[164]	7	hSpCas9	negative selection	10634303
104949666	104949689	11	+	28162770	SKM1	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	-0.09740466128621783	[327]	[541]	-1	hSpCas9	negative selection	10634304
104948596	104948619	11	-	28162770	SKM1	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	0.9187554753065748	[37]	[126]	8	hSpCas9	negative selection	10634305
104951015	104951038	11	-	28162770	SKM1	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.5405683813627027	[34]	[89]	5	hSpCas9	negative selection	10634306
104951001	104951024	11	+	28162770	SKM1	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.23689199103156294	[35]	[74]	2	hSpCas9	negative selection	10634307
104949757	104949780	11	-	28162770	SKM1	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.3074285251922473	[27]	[39]	-3	hSpCas9	negative selection	10634308
104951059	104951082	11	-	28162770	SKM1	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	-0.023635559191656053	[68]	[119]	0	hSpCas9	negative selection	10634309
104948563	104948586	11	-	28162770	SKM1	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.04608662647241357	[102]	[187]	0	hSpCas9	negative selection	10634310
104950968	104950991	11	-	28162770	SKM1	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	0.608632656307857	[45]	[123]	6	hSpCas9	negative selection	10634311
104949680	104949703	11	-	28162770	SKM1	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	1.15888947903029	[56]	[224]	9	hSpCas9	negative selection	10634312
104948667	104948690	11	-	28162770	PL21	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	-0.5841316944552427	[247]	[71]	-4	hSpCas9	negative selection	10803669
104949666	104949689	11	+	28162770	PL21	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.602861791334925	[999]	[660]	5	hSpCas9	negative selection	10803670
104948596	104948619	11	-	28162770	PL21	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.2803099631733033	[139]	[147]	9	hSpCas9	negative selection	10803671
104951015	104951038	11	-	28162770	PL21	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	1.6401811198980585	[142]	[193]	9	hSpCas9	negative selection	10803672
104951001	104951024	11	+	28162770	PL21	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	-0.674329503426821	[120]	[32]	-5	hSpCas9	negative selection	10803673
104949757	104949780	11	-	28162770	PL21	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.507117367910711	[96]	[59]	4	hSpCas9	negative selection	10803674
104951059	104951082	11	-	28162770	PL21	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.04115009072816339	[229]	[102]	0	hSpCas9	negative selection	10803675
104948563	104948586	11	-	28162770	PL21	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.854450161901211	[351]	[276]	7	hSpCas9	negative selection	10803676
104950968	104950991	11	-	28162770	PL21	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.2181730168223847	[146]	[54]	-1	hSpCas9	negative selection	10803677
104949680	104949703	11	-	28162770	PL21	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	1.1241907612560216	[233]	[221]	8	hSpCas9	negative selection	10803678
104948667	104948690	11	-	28162770	P31FUJ	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.23130590143239177	[223]	[308]	2	hSpCas9	negative selection	10973035
104949666	104949689	11	+	28162770	P31FUJ	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.10352771074316047	[1534]	[1937]	1	hSpCas9	negative selection	10973036
104948596	104948619	11	-	28162770	P31FUJ	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.1799793209240972	[79]	[212]	9	hSpCas9	negative selection	10973037
104951015	104951038	11	-	28162770	P31FUJ	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.3287013234827887	[123]	[182]	3	hSpCas9	negative selection	10973038
104951001	104951024	11	+	28162770	P31FUJ	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.03911035276586794	[134]	[162]	0	hSpCas9	negative selection	10973039
104949757	104949780	11	-	28162770	P31FUJ	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.245660675006099	[88]	[123]	2	hSpCas9	negative selection	10973040
104951059	104951082	11	-	28162770	P31FUJ	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.07614803647477375	[267]	[331]	0	hSpCas9	negative selection	10973041
104948563	104948586	11	-	28162770	P31FUJ	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.7115838203746219	[475]	[915]	7	hSpCas9	negative selection	10973042
104950968	104950991	11	-	28162770	P31FUJ	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.01584366912855851	[227]	[264]	0	hSpCas9	negative selection	10973043
104949680	104949703	11	-	28162770	P31FUJ	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.016337759761034354	[312]	[371]	0	hSpCas9	negative selection	10973044
104948667	104948690	11	-	28162770	OCIAML5	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.7841646001676693	[128]	[400]	7	hSpCas9	negative selection	11142401
104949666	104949689	11	+	28162770	OCIAML5	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.6090973213945374	[680]	[1874]	5	hSpCas9	negative selection	11142402
104948596	104948619	11	-	28162770	OCIAML5	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	0.6763124014907915	[77]	[224]	6	hSpCas9	negative selection	11142403
104951015	104951038	11	-	28162770	OCIAML5	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.42804134832873836	[69]	[169]	3	hSpCas9	negative selection	11142404
104951001	104951024	11	+	28162770	OCIAML5	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.3703258504724508	[62]	[146]	3	hSpCas9	negative selection	11142405
104949757	104949780	11	-	28162770	OCIAML5	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.4109678349697967	[34]	[83]	3	hSpCas9	negative selection	11142406
104951059	104951082	11	-	28162770	OCIAML5	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.5008144523522775	[165]	[423]	4	hSpCas9	negative selection	11142407
104948563	104948586	11	-	28162770	OCIAML5	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.7966964405588821	[316]	[993]	7	hSpCas9	negative selection	11142408
104950968	104950991	11	-	28162770	OCIAML5	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	1.029752002787689	[88]	[327]	8	hSpCas9	negative selection	11142409
104949680	104949703	11	-	28162770	OCIAML5	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.2458471856629273	[177]	[380]	2	hSpCas9	negative selection	11142410
104948667	104948690	11	-	28162770	EOL1	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.7854358919785609	[358]	[325]	7	hSpCas9	negative selection	11311767
104949666	104949689	11	+	28162770	EOL1	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.43147153397141924	[1474]	[1047]	4	hSpCas9	negative selection	11311768
104948596	104948619	11	-	28162770	EOL1	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.3931663110542223	[184]	[255]	9	hSpCas9	negative selection	11311769
104951015	104951038	11	-	28162770	EOL1	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.34970948812308567	[212]	[142]	3	hSpCas9	negative selection	11311770
104951001	104951024	11	+	28162770	EOL1	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.5095102722916907	[227]	[170]	4	hSpCas9	negative selection	11311771
104949757	104949780	11	-	28162770	EOL1	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.5171576781703893	[181]	[66]	-4	hSpCas9	negative selection	11311772
104951059	104951082	11	-	28162770	EOL1	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	1.7204446489595309	[306]	[532]	9	hSpCas9	negative selection	11311773
104948563	104948586	11	-	28162770	EOL1	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.2333004777101637	[527]	[326]	2	hSpCas9	negative selection	11311774
104950968	104950991	11	-	28162770	EOL1	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.26714785254299694	[216]	[94]	-2	hSpCas9	negative selection	11311775
104949680	104949703	11	-	28162770	EOL1	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.06489084784300747	[322]	[177]	0	hSpCas9	negative selection	11311776
104948667	104948690	11	-	28162770	MOLM13	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.15564745162715066	[333]	[268]	1	hSpCas9	negative selection	11481133
104949666	104949689	11	+	28162770	MOLM13	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.29252229503401805	[1493]	[1322]	2	hSpCas9	negative selection	11481134
104948596	104948619	11	-	28162770	MOLM13	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	0.5881836152622905	[206]	[224]	4	hSpCas9	negative selection	11481135
104951015	104951038	11	-	28162770	MOLM13	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.8620295399301567	[225]	[296]	6	hSpCas9	negative selection	11481136
104951001	104951024	11	+	28162770	MOLM13	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.7973511491173486	[190]	[239]	6	hSpCas9	negative selection	11481137
104949757	104949780	11	-	28162770	MOLM13	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.23837941539871077	[154]	[94]	-1	hSpCas9	negative selection	11481138
104951059	104951082	11	-	28162770	MOLM13	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.33956528456903934	[422]	[386]	2	hSpCas9	negative selection	11481139
104948563	104948586	11	-	28162770	MOLM13	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	1.2571068764463837	[525]	[908]	8	hSpCas9	negative selection	11481140
104950968	104950991	11	-	28162770	MOLM13	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.06330186273559674	[236]	[163]	0	hSpCas9	negative selection	11481141
104949680	104949703	11	-	28162770	MOLM13	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.6203154906914982	[340]	[378]	4	hSpCas9	negative selection	11481142
104948667	104948690	11	-	28162770	HEL	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.7868400579847157	[237]	[262]	6	hSpCas9	negative selection	11650499
104949666	104949689	11	+	28162770	HEL	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.5192948807605018	[1255]	[1152]	4	hSpCas9	negative selection	11650500
104948596	104948619	11	-	28162770	HEL	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	0.39906975103349424	[147]	[124]	3	hSpCas9	negative selection	11650501
104951015	104951038	11	-	28162770	HEL	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	-0.2840121859690045	[191]	[100]	-2	hSpCas9	negative selection	11650502
104951001	104951024	11	+	28162770	HEL	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.9792643031006774	[117]	[148]	8	hSpCas9	negative selection	11650503
104949757	104949780	11	-	28162770	HEL	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	1.5002945669801515	[116]	[211]	9	hSpCas9	negative selection	11650504
104951059	104951082	11	-	28162770	HEL	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.31985877730221624	[378]	[302]	2	hSpCas9	negative selection	11650505
104948563	104948586	11	-	28162770	HEL	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.6392997480335859	[419]	[418]	5	hSpCas9	negative selection	11650506
104950968	104950991	11	-	28162770	HEL	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.8860408333276752	[276]	[95]	-5	hSpCas9	negative selection	11650507
104949680	104949703	11	-	28162770	HEL	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.8226479220152914	[255]	[289]	7	hSpCas9	negative selection	11650508
104948667	104948690	11	-	28162770	MV411	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.005161705115779014	[206]	[174]	0	hSpCas9	negative selection	11819865
104949666	104949689	11	+	28162770	MV411	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.8376023667459855	[1014]	[1527]	7	hSpCas9	negative selection	11819866
104948596	104948619	11	-	28162770	MV411	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.502010377868373	[113]	[271]	9	hSpCas9	negative selection	11819867
104951015	104951038	11	-	28162770	MV411	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.9718031081693479	[91]	[151]	8	hSpCas9	negative selection	11819868
104951001	104951024	11	+	28162770	MV411	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	-0.19037125615472666	[148]	[109]	-1	hSpCas9	negative selection	11819869
104949757	104949780	11	-	28162770	MV411	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.5826374477749121	[79]	[44]	-4	hSpCas9	negative selection	11819870
104951059	104951082	11	-	28162770	MV411	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.08337478837312273	[306]	[273]	0	hSpCas9	negative selection	11819871
104948563	104948586	11	-	28162770	MV411	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.3131254538500169	[321]	[336]	2	hSpCas9	negative selection	11819872
104950968	104950991	11	-	28162770	MV411	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.36197799366292005	[118]	[77]	-3	hSpCas9	negative selection	11819873
104949680	104949703	11	-	28162770	MV411	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.7201905479179065	[244]	[339]	6	hSpCas9	negative selection	11819874
104948667	104948690	11	-	28162770	MONOMAC1	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	1.450661409009565	[119]	[375]	9	hSpCas9	negative selection	11989231
104949666	104949689	11	+	28162770	MONOMAC1	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.4378463914453916	[728]	[1131]	4	hSpCas9	negative selection	11989232
104948596	104948619	11	-	28162770	MONOMAC1	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	1.1336084649289175	[65]	[165]	8	hSpCas9	negative selection	11989233
104951015	104951038	11	-	28162770	MONOMAC1	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	-0.25253195965125724	[105]	[101]	-2	hSpCas9	negative selection	11989234
104951001	104951024	11	+	28162770	MONOMAC1	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	-0.3080681594482976	[80]	[74]	-3	hSpCas9	negative selection	11989235
104949757	104949780	11	-	28162770	MONOMAC1	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.1469175541578076	[51]	[65]	1	hSpCas9	negative selection	11989236
104951059	104951082	11	-	28162770	MONOMAC1	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	-0.1460529183407489	[138]	[143]	-1	hSpCas9	negative selection	11989237
104948563	104948586	11	-	28162770	MONOMAC1	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.3251428198806089	[226]	[325]	3	hSpCas9	negative selection	11989238
104950968	104950991	11	-	28162770	MONOMAC1	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	0.28054211828800296	[78]	[109]	3	hSpCas9	negative selection	11989239
104949680	104949703	11	-	28162770	MONOMAC1	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.04669203597744925	[162]	[192]	0	hSpCas9	negative selection	11989240
104948667	104948690	11	-	28162770	OCIAML2	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.21621228949820848	[40]	[263]	2	hSpCas9	negative selection	12158597
104949666	104949689	11	+	28162770	OCIAML2	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.31139549154269597	[196]	[1354]	3	hSpCas9	negative selection	12158598
104948596	104948619	11	-	28162770	OCIAML2	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	0.9274012487309928	[23]	[252]	8	hSpCas9	negative selection	12158599
104951015	104951038	11	-	28162770	OCIAML2	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.460107512320725	[23]	[182]	4	hSpCas9	negative selection	12158600
104951001	104951024	11	+	28162770	OCIAML2	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.5293701747578388	[18]	[151]	5	hSpCas9	negative selection	12158601
104949757	104949780	11	-	28162770	OCIAML2	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	0.381812986343981	[17]	[129]	3	hSpCas9	negative selection	12158602
104951059	104951082	11	-	28162770	OCIAML2	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.10970122674734917	[51]	[310]	1	hSpCas9	negative selection	12158603
104948563	104948586	11	-	28162770	OCIAML2	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.6831755108368743	[59]	[533]	6	hSpCas9	negative selection	12158604
104950968	104950991	11	-	28162770	OCIAML2	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.7731925952625924	[36]	[119]	-5	hSpCas9	negative selection	12158605
104949680	104949703	11	-	28162770	OCIAML2	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	0.2188886065215847	[50]	[328]	2	hSpCas9	negative selection	12158606
104948667	104948690	11	-	28162770	OCIAML3	viability	AATGTCTCCATAGCAAACCGTGG	CASP4	ENSG00000196954	0.26557724050599874	[61]	[224]	2	hSpCas9	negative selection	12327963
104949666	104949689	11	+	28162770	OCIAML3	viability	CAGTTCCGCAGATTCCCTCCAGG	CASP4	ENSG00000196954	0.7133721459940436	[298]	[1479]	6	hSpCas9	negative selection	12327964
104948596	104948619	11	-	28162770	OCIAML3	viability	ACAGTCATCTGAGAACCTAGAGG	CASP4	ENSG00000196954	0.632060439155683	[27]	[130]	6	hSpCas9	negative selection	12327965
104951015	104951038	11	-	28162770	OCIAML3	viability	AGTTTGACCATCTGCCTCCGAGG	CASP4	ENSG00000196954	0.37902531207556744	[26]	[105]	3	hSpCas9	negative selection	12327966
104951001	104951024	11	+	28162770	OCIAML3	viability	AAGTCAGCTCCATTCCTCGGAGG	CASP4	ENSG00000196954	0.9084927002050202	[26]	[152]	7	hSpCas9	negative selection	12327967
104949757	104949780	11	-	28162770	OCIAML3	viability	AGGATATGGAGTCAGCGCTGAGG	CASP4	ENSG00000196954	-0.6464750602182986	[27]	[53]	-5	hSpCas9	negative selection	12327968
104951059	104951082	11	-	28162770	OCIAML3	viability	GAGAAACAACCGCACACGCCTGG	CASP4	ENSG00000196954	0.1843606528526056	[78]	[270]	1	hSpCas9	negative selection	12327969
104948563	104948586	11	-	28162770	OCIAML3	viability	TTACAAGACCCACGTGGAGAAGG	CASP4	ENSG00000196954	0.5289198815809797	[103]	[452]	5	hSpCas9	negative selection	12327970
104950968	104950991	11	-	28162770	OCIAML3	viability	GGGATGAAGGAGCTACTTGAGGG	CASP4	ENSG00000196954	-0.1789701410453193	[53]	[143]	-1	hSpCas9	negative selection	12327971
104949680	104949703	11	-	28162770	OCIAML3	viability	ATGTCTCATGGCATCCTGGAGGG	CASP4	ENSG00000196954	-0.08352335556228348	[52]	[150]	0	hSpCas9	negative selection	12327972