Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:839
• Symbol:CASP6
• Description:caspase 6

DataSource: http://genomecrispr.dkfz.de/#!/results/CASP6

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
109694643	109694666	4	-	26472758	Jiyoye	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.1855609030520604	[308]	[264]	1	hSpCas9	negative selection	23779
109690999	109691022	4	-	26472758	Jiyoye	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.6702097873396671	[64]	[77]	5	hSpCas9	negative selection	23780
109690973	109690996	4	+	26472758	Jiyoye	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	1.8131677411817102	[59]	[158]	8	hSpCas9	negative selection	23781
109690887	109690910	4	+	26472758	Jiyoye	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.6049057486080521	[176]	[202]	4	hSpCas9	negative selection	23782
109694626	109694649	4	+	26472758	Jiyoye	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.3127106975023808	[70]	[132]	7	hSpCas9	negative selection	23783
109690919	109690942	4	-	26472758	Jiyoye	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.5771003829481858	[343]	[386]	4	hSpCas9	negative selection	23784
109694550	109694573	4	-	26472758	Jiyoye	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.9477437628685759	[32]	[47]	6	hSpCas9	negative selection	23785
109703386	109703409	4	-	26472758	Jiyoye	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	-0.5599932260267544	[390]	[199]	-4	hSpCas9	negative selection	23786
109690853	109690876	4	+	26472758	Jiyoye	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.42138924072557427	[201]	[203]	3	hSpCas9	negative selection	23787
109694665	109694688	4	+	26472758	Jiyoye	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	-0.17778711921528279	[221]	[147]	-1	hSpCas9	negative selection	23788
109694643	109694666	4	-	26472758	KBM7	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.289183410396497	[1360,1105]	[899,529]	3	hSpCas9	negative selection	214897
109690999	109691022	4	-	26472758	KBM7	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.1021490284467169	[588,418]	[284,220]	1	hSpCas9	negative selection	214898
109690973	109690996	4	+	26472758	KBM7	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	-0.009919562370222845	[1105,920]	[590,363]	0	hSpCas9	negative selection	214899
109690887	109690910	4	+	26472758	KBM7	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.0175274362327823	[886,905]	[363,467]	0	hSpCas9	negative selection	214900
109694626	109694649	4	+	26472758	KBM7	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.3487419110607255	[402,315]	[164,101]	-3	hSpCas9	negative selection	214901
109690919	109690942	4	-	26472758	KBM7	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.27760125938147784	[1616,1549]	[1122,709]	3	hSpCas9	negative selection	214902
109694550	109694573	4	-	26472758	KBM7	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.2899595921349932	[512,471]	[258,304]	3	hSpCas9	negative selection	214903
109703386	109703409	4	-	26472758	KBM7	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.28171728874633617	[1517,1476]	[822,890]	3	hSpCas9	negative selection	214904
109690853	109690876	4	+	26472758	KBM7	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.17080151439164876	[711,592]	[318,365]	1	hSpCas9	negative selection	214905
109694665	109694688	4	+	26472758	KBM7	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.41212242236046503	[1092,605]	[461,568]	4	hSpCas9	negative selection	214906
109694643	109694666	4	-	26472758	Raji	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.20099802767581476	[529]	[106]	-2	hSpCas9	negative selection	406015
109690999	109691022	4	-	26472758	Raji	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.31529536996930596	[328]	[94]	3	hSpCas9	negative selection	406016
109690973	109690996	4	+	26472758	Raji	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.6680984898480784	[319]	[117]	6	hSpCas9	negative selection	406017
109690887	109690910	4	+	26472758	Raji	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.39511680515558384	[339]	[59]	-3	hSpCas9	negative selection	406018
109694626	109694649	4	+	26472758	Raji	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.47935231276055734	[169]	[54]	4	hSpCas9	negative selection	406019
109690919	109690942	4	-	26472758	Raji	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.6180813871541648	[670]	[238]	6	hSpCas9	negative selection	406020
109694550	109694573	4	-	26472758	Raji	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	-0.06516693547553618	[274]	[60]	0	hSpCas9	negative selection	406021
109703386	109703409	4	-	26472758	Raji	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.359013177935144	[634]	[188]	3	hSpCas9	negative selection	406022
109690853	109690876	4	+	26472758	Raji	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.4968859425453058	[341]	[111]	5	hSpCas9	negative selection	406023
109694665	109694688	4	+	26472758	Raji	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.6048831948444164	[254]	[89]	6	hSpCas9	negative selection	406024
109694643	109694666	4	-	26472758	K562	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.004467934945694418	[991]	[839]	0	hSpCas9	negative selection	597133
109690999	109691022	4	-	26472758	K562	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.8515769745017994	[429]	[654]	7	hSpCas9	negative selection	597134
109690973	109690996	4	+	26472758	K562	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	1.3496217595130717	[541]	[1165]	9	hSpCas9	negative selection	597135
109690887	109690910	4	+	26472758	K562	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.34187247428320877	[600]	[642]	2	hSpCas9	negative selection	597136
109694626	109694649	4	+	26472758	K562	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.7838915299048205	[246]	[358]	6	hSpCas9	negative selection	597137
109690919	109690942	4	-	26472758	K562	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.11167753638202971	[1239]	[1130]	0	hSpCas9	negative selection	597138
109694550	109694573	4	-	26472758	K562	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	-0.04826113991587165	[353]	[288]	0	hSpCas9	negative selection	597139
109703386	109703409	4	-	26472758	K562	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.4861012989173976	[1315]	[1555]	4	hSpCas9	negative selection	597140
109690853	109690876	4	+	26472758	K562	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.3756632609446995	[608]	[666]	3	hSpCas9	negative selection	597141
109694665	109694688	4	+	26472758	K562	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	1.2918396322760668	[403]	[834]	9	hSpCas9	negative selection	597142
109689450	109689473	4	-	26627737	DLD1	viability	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	-0.02010231126229911	[678]	[219,119,273]	0	hSpCas9	negative selection	823532
109689468	109689491	4	+	26627737	DLD1	viability	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.583483240887511	[52]	[26,31,16]	6	hSpCas9	negative selection	823533
109690887	109690910	4	+	26627737	DLD1	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	1.1749844708671864	[602]	[470,536,293]	9	hSpCas9	negative selection	823534
109694626	109694649	4	+	26627737	DLD1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-1.284136399682969	[509]	[63,75,57]	-8	hSpCas9	negative selection	823535
109697621	109697644	4	-	26627737	DLD1	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.0052555812997983065	[282]	[63,134,71]	0	hSpCas9	negative selection	823536
109697660	109697683	4	-	26627737	DLD1	viability	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.5589593183798595	[202]	[84,79,111]	5	hSpCas9	negative selection	823537
109689450	109689473	4	-	26627737	GBM cells	viability after 5 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.11879069830335076	[327]	[239,141]	2	hSpCas9	negative selection	905847
109689468	109689491	4	+	26627737	GBM cells	viability after 5 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	-0.5161236243931584	[59]	[17,26]	-7	hSpCas9	negative selection	905848
109690887	109690910	4	+	26627737	GBM cells	viability after 5 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.19313433413548542	[452]	[219,204]	-3	hSpCas9	negative selection	905849
109694626	109694649	4	+	26627737	GBM cells	viability after 5 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.02877192029842432	[213]	[123,100]	0	hSpCas9	negative selection	905850
109697621	109697644	4	-	26627737	GBM cells	viability after 5 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.02360962233500019	[143]	[65,90]	0	hSpCas9	negative selection	905851
109697660	109697683	4	-	26627737	GBM cells	viability after 5 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.29074398300320403	[140]	[103,80]	4	hSpCas9	negative selection	905852
109689450	109689473	4	-	26627737	GBM cells	viability after 13 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.49249782477307136	[327]	[315,196]	6	hSpCas9	negative selection	988162
109689468	109689491	4	+	26627737	GBM cells	viability after 13 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	-0.6512825507099889	[59]	[28,13]	-6	hSpCas9	negative selection	988163
109690887	109690910	4	+	26627737	GBM cells	viability after 13 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.11934948210373586	[452]	[292,171]	-1	hSpCas9	negative selection	988164
109694626	109694649	4	+	26627737	GBM cells	viability after 13 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.05087281126087073	[213]	[153,77]	0	hSpCas9	negative selection	988165
109697621	109697644	4	-	26627737	GBM cells	viability after 13 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.46509983159746154	[143]	[87,123]	6	hSpCas9	negative selection	988166
109697660	109697683	4	-	26627737	GBM cells	viability after 13 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.10925968120129692	[140]	[92,73]	1	hSpCas9	negative selection	988167
109689450	109689473	4	-	26627737	GBM cells	viability after 21 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.5741621603389084	[327]	[269,260]	6	hSpCas9	negative selection	1070477
109689468	109689491	4	+	26627737	GBM cells	viability after 21 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	-0.7047292011054975	[59]	[19,19]	-6	hSpCas9	negative selection	1070478
109690887	109690910	4	+	26627737	GBM cells	viability after 21 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.39503987659115736	[452]	[206,168]	-4	hSpCas9	negative selection	1070479
109694626	109694649	4	+	26627737	GBM cells	viability after 21 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.5073212760094912	[213]	[170,159]	5	hSpCas9	negative selection	1070480
109697621	109697644	4	-	26627737	GBM cells	viability after 21 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.3580065542424648	[143]	[93,105]	4	hSpCas9	negative selection	1070481
109697660	109697683	4	-	26627737	GBM cells	viability after 21 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.36890469138494164	[140]	[88,107]	4	hSpCas9	negative selection	1070482
109689450	109689473	4	-	26627737	RPE1	viability after 9 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	-0.5826417099762061	[1313]	[337,192]	-4	hSpCas9	negative selection	1152792
109689468	109689491	4	+	26627737	RPE1	viability after 9 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	2.4187842068936254	[62]	[87,127]	9	hSpCas9	negative selection	1152793
109690887	109690910	4	+	26627737	RPE1	viability after 9 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.31081276090337207	[1771]	[441,453]	-2	hSpCas9	negative selection	1152794
109694626	109694649	4	+	26627737	RPE1	viability after 9 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.17204247444263343	[527]	[130,166]	-1	hSpCas9	negative selection	1152795
109697621	109697644	4	-	26627737	RPE1	viability after 9 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.8906480083664371	[241]	[153,122]	6	hSpCas9	negative selection	1152796
109697660	109697683	4	-	26627737	RPE1	viability after 9 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	1.3358726687437437	[483]	[316,466]	7	hSpCas9	negative selection	1152797
109689450	109689473	4	-	26627737	RPE1	viability after 12 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	-0.5878229873544522	[1313]	[230,238]	-4	hSpCas9	negative selection	1235107
109689468	109689491	4	+	26627737	RPE1	viability after 12 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	2.2642684177547374	[62]	[57,105]	9	hSpCas9	negative selection	1235108
109690887	109690910	4	+	26627737	RPE1	viability after 12 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.027893899520554877	[1771]	[565,399]	0	hSpCas9	negative selection	1235109
109694626	109694649	4	+	26627737	RPE1	viability after 12 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.0970349172857996	[527]	[187,73]	0	hSpCas9	negative selection	1235110
109697621	109697644	4	-	26627737	RPE1	viability after 12 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.3592236529558448	[241]	[62,104]	2	hSpCas9	negative selection	1235111
109697660	109697683	4	-	26627737	RPE1	viability after 12 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	1.168201602695226	[483]	[282,301]	7	hSpCas9	negative selection	1235112
109689450	109689473	4	-	26627737	RPE1	viability after 15 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	-0.3806194536045972	[1313]	[256,312]	-2	hSpCas9	negative selection	1317422
109689468	109689491	4	+	26627737	RPE1	viability after 15 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	2.963198668453617	[62]	[111,164]	9	hSpCas9	negative selection	1317423
109690887	109690910	4	+	26627737	RPE1	viability after 15 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.4221879549249571	[1771]	[312,432]	-3	hSpCas9	negative selection	1317424
109694626	109694649	4	+	26627737	RPE1	viability after 15 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.43847183839239373	[527]	[291,115]	3	hSpCas9	negative selection	1317425
109697621	109697644	4	-	26627737	RPE1	viability after 15 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.34308775756027177	[241]	[67,104]	2	hSpCas9	negative selection	1317426
109697660	109697683	4	-	26627737	RPE1	viability after 15 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	1.2449100107162618	[483]	[296,350]	7	hSpCas9	negative selection	1317427
109689450	109689473	4	-	26627737	RPE1	viability after 18 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	-0.8519915944253732	[1313]	[136,259]	-5	hSpCas9	negative selection	1399737
109689468	109689491	4	+	26627737	RPE1	viability after 18 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	3.0272901758283313	[62]	[68,212]	9	hSpCas9	negative selection	1399738
109690887	109690910	4	+	26627737	RPE1	viability after 18 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.05260474198453813	[1771]	[448,473]	0	hSpCas9	negative selection	1399739
109694626	109694649	4	+	26627737	RPE1	viability after 18 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.4968529022227681	[527]	[143,54]	-3	hSpCas9	negative selection	1399740
109697621	109697644	4	-	26627737	RPE1	viability after 18 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.12813998367825352	[241]	[23,121]	0	hSpCas9	negative selection	1399741
109697660	109697683	4	-	26627737	RPE1	viability after 18 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	1.2751266045269412	[483]	[406,218]	7	hSpCas9	negative selection	1399742
109689450	109689473	4	-	26627737	HeLa	viability after 8 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.6372942518533843	[464]	[457,340,185]	5	hSpCas9	negative selection	1482052
109689468	109689491	4	+	26627737	HeLa	viability after 8 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	-1.5824978748666818	[255]	[35,62,13]	-9	hSpCas9	negative selection	1482053
109690887	109690910	4	+	26627737	HeLa	viability after 8 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.6852170128091954	[982]	[320,383,115]	-6	hSpCas9	negative selection	1482054
109694626	109694649	4	+	26627737	HeLa	viability after 8 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-1.8702139687103914	[276]	[37,13,46]	-9	hSpCas9	negative selection	1482055
109697621	109697644	4	-	26627737	HeLa	viability after 8 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.8728927067368828	[180]	[107,220,98]	7	hSpCas9	negative selection	1482056
109697660	109697683	4	-	26627737	HeLa	viability after 8 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.2902686806494673	[224]	[111,177,70]	2	hSpCas9	negative selection	1482057
109689450	109689473	4	-	26627737	HeLa	viability after 12 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.5227100599233576	[464]	[355,186,296]	4	hSpCas9	negative selection	1564367
109689468	109689491	4	+	26627737	HeLa	viability after 12 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	-1.3798005287591457	[255]	[26,45,47]	-8	hSpCas9	negative selection	1564368
109690887	109690910	4	+	26627737	HeLa	viability after 12 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-1.2709175628423424	[982]	[149,257,86]	-8	hSpCas9	negative selection	1564369
109694626	109694649	4	+	26627737	HeLa	viability after 12 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.735438617141311	[276]	[62,31,114]	-6	hSpCas9	negative selection	1564370
109697621	109697644	4	-	26627737	HeLa	viability after 12 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.368464840090291	[180]	[55,17,103]	-3	hSpCas9	negative selection	1564371
109697660	109697683	4	-	26627737	HeLa	viability after 12 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	-0.04348102219312078	[224]	[27,154,78]	0	hSpCas9	negative selection	1564372
109689450	109689473	4	-	26627737	HeLa	viability after 15 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	-0.02143124821446618	[464]	[177,214,164]	0	hSpCas9	negative selection	1646682
109689468	109689491	4	+	26627737	HeLa	viability after 15 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	-1.701853789332393	[255]	[20,9,67]	-9	hSpCas9	negative selection	1646683
109690887	109690910	4	+	26627737	HeLa	viability after 15 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.16341778172247334	[982]	[491,487,356]	1	hSpCas9	negative selection	1646684
109694626	109694649	4	+	26627737	HeLa	viability after 15 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-1.0357866249205465	[276]	[24,65,75]	-7	hSpCas9	negative selection	1646685
109697621	109697644	4	-	26627737	HeLa	viability after 15 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.08036729417320365	[180]	[85,52,95]	0	hSpCas9	negative selection	1646686
109697660	109697683	4	-	26627737	HeLa	viability after 15 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.7503675847161139	[224]	[92,119,257]	6	hSpCas9	negative selection	1646687
109689450	109689473	4	-	26627737	HeLa	viability after 18 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.018366978375164295	[464]	[127,179,164]	0	hSpCas9	negative selection	1728997
109689468	109689491	4	+	26627737	HeLa	viability after 18 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	-1.6454284914086093	[255]	[15,8,67]	-8	hSpCas9	negative selection	1728998
109690887	109690910	4	+	26627737	HeLa	viability after 18 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.15781790998132927	[982]	[329,399,356]	1	hSpCas9	negative selection	1728999
109694626	109694649	4	+	26627737	HeLa	viability after 18 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.9659540193014624	[276]	[20,55,75]	-7	hSpCas9	negative selection	1729000
109697621	109697644	4	-	26627737	HeLa	viability after 18 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.11599093448892317	[180]	[58,46,95]	1	hSpCas9	negative selection	1729001
109697660	109697683	4	-	26627737	HeLa	viability after 18 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.7431756000174543	[224]	[57,102,257]	6	hSpCas9	negative selection	1729002
109689450	109689473	4	-	26627737	HCT116	viability after 6 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	-0.40669431136821577	[1163]	[41,190]	-2	hSpCas9	negative selection	1811312
109689468	109689491	4	+	26627737	HCT116	viability after 6 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	-2.201104462395837	[116]	[3,3]	-8	hSpCas9	negative selection	1811313
109690887	109690910	4	+	26627737	HCT116	viability after 6 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.7984335906261795	[1057]	[238,316]	4	hSpCas9	negative selection	1811314
109694626	109694649	4	+	26627737	HCT116	viability after 6 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.8536338299571136	[521]	[105,11]	-5	hSpCas9	negative selection	1811315
109697621	109697644	4	-	26627737	HCT116	viability after 6 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.032802777844690434	[270]	[11,60]	0	hSpCas9	negative selection	1811316
109697660	109697683	4	-	26627737	HCT116	viability after 6 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	-0.7308156312940155	[318]	[55,15]	-4	hSpCas9	negative selection	1811317
109689450	109689473	4	-	26627737	HCT116	viability after 8 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.2975806060691279	[356]	[228,244,250]	3	hSpCas9	negative selection	1893627
109689468	109689491	4	+	26627737	HCT116	viability after 8 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.9951523992900879	[44]	[36,56,53]	8	hSpCas9	negative selection	1893628
109690887	109690910	4	+	26627737	HCT116	viability after 8 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.08931332263101799	[442]	[308,169,210]	-1	hSpCas9	negative selection	1893629
109694626	109694649	4	+	26627737	HCT116	viability after 8 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.27695715899555085	[206]	[92,144,44]	-3	hSpCas9	negative selection	1893630
109697621	109697644	4	-	26627737	HCT116	viability after 8 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.6647365008053503	[231]	[121,67,52]	-7	hSpCas9	negative selection	1893631
109697660	109697683	4	-	26627737	HCT116	viability after 8 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.6647700403553635	[158]	[155,122,137]	6	hSpCas9	negative selection	1893632
109689450	109689473	4	-	26627737	HCT116	viability after 9 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	-0.24755431538471762	[1163]	[277,248]	-2	hSpCas9	negative selection	1975942
109689468	109689491	4	+	26627737	HCT116	viability after 9 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	1.4381937587955615	[116]	[44,115]	8	hSpCas9	negative selection	1975943
109690887	109690910	4	+	26627737	HCT116	viability after 9 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.6248016521057043	[1057]	[185,180]	-4	hSpCas9	negative selection	1975944
109694626	109694649	4	+	26627737	HCT116	viability after 9 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.011475006130819893	[521]	[44,211]	0	hSpCas9	negative selection	1975945
109697621	109697644	4	-	26627737	HCT116	viability after 9 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-1.7325733385849265	[270]	[42,4]	-8	hSpCas9	negative selection	1975946
109697660	109697683	4	-	26627737	HCT116	viability after 9 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	-0.346527613842025	[318]	[109,32]	-2	hSpCas9	negative selection	1975947
109689450	109689473	4	-	26627737	HCT116	viability after 12 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.5680372256639994	[356]	[306,241,281]	5	hSpCas9	negative selection	2058257
109689468	109689491	4	+	26627737	HCT116	viability after 12 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.03092832845763871	[44]	[30,28,11]	0	hSpCas9	negative selection	2058258
109690887	109690910	4	+	26627737	HCT116	viability after 12 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.10605235846805283	[442]	[264,273,211]	1	hSpCas9	negative selection	2058259
109694626	109694649	4	+	26627737	HCT116	viability after 12 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.15686332318701507	[206]	[120,126,115]	1	hSpCas9	negative selection	2058260
109697621	109697644	4	-	26627737	HCT116	viability after 12 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.176722754053629	[231]	[204,115,85]	1	hSpCas9	negative selection	2058261
109697660	109697683	4	-	26627737	HCT116	viability after 12 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.7830021247003883	[158]	[94,117,221]	7	hSpCas9	negative selection	2058262
109689450	109689473	4	-	26627737	HCT116	viability after 15 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.6310545992032055	[356]	[314,298,337]	6	hSpCas9	negative selection	2140572
109689468	109689491	4	+	26627737	HCT116	viability after 15 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.058929428847834586	[44]	[36,18,25]	0	hSpCas9	negative selection	2140573
109690887	109690910	4	+	26627737	HCT116	viability after 15 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.007688197788318085	[442]	[503,221,65]	0	hSpCas9	negative selection	2140574
109694626	109694649	4	+	26627737	HCT116	viability after 15 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.11577252015497369	[206]	[101,54,224]	1	hSpCas9	negative selection	2140575
109697621	109697644	4	-	26627737	HCT116	viability after 15 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.4574177925304159	[231]	[152,137,7]	-5	hSpCas9	negative selection	2140576
109697660	109697683	4	-	26627737	HCT116	viability after 15 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.885410453434067	[158]	[143,103,253]	7	hSpCas9	negative selection	2140577
109689450	109689473	4	-	26627737	HCT116	viability after 18 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.13594452129412843	[356]	[261,167,137]	1	hSpCas9	negative selection	2222887
109689468	109689491	4	+	26627737	HCT116	viability after 18 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	-0.342337895164488	[44]	[13,13,23]	-3	hSpCas9	negative selection	2222888
109690887	109690910	4	+	26627737	HCT116	viability after 18 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.5104795921856112	[442]	[376,294,240]	4	hSpCas9	negative selection	2222889
109694626	109694649	4	+	26627737	HCT116	viability after 18 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.15562647888461367	[206]	[109,89,136]	1	hSpCas9	negative selection	2222890
109697621	109697644	4	-	26627737	HCT116	viability after 18 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.7615354889845019	[231]	[94,66,34]	-6	hSpCas9	negative selection	2222891
109697660	109697683	4	-	26627737	HCT116	viability after 18 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.8073053740528702	[158]	[152,45,213]	6	hSpCas9	negative selection	2222892
109694574	109694597	4	-	24336569	HL60	viability	ACATTAACTGGCTTGTTCAAAGG	CASP6	ENSG00000138794	0.42774897940571077	[390]	[1112]	4	hSpCas9	negative selection	2254486
109694586	109694609	4	-	24336569	HL60	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.9814352822976244	[389]	[417]	-7	hSpCas9	negative selection	2254487
109694626	109694649	4	+	24336569	HL60	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.40482121811139005	[599]	[1680]	3	hSpCas9	negative selection	2254488
109694632	109694655	4	+	24336569	HL60	viability	GATTGCCTTCGCCATGGCTCAGG	CASP6	ENSG00000138794	1.397268073967337	[107]	[601]	8	hSpCas9	negative selection	2254489
109694637	109694660	4	-	24336569	HL60	viability	GTCTTCCTGAGCCATGGCGAAGG	CASP6	ENSG00000138794	0.7819012073492579	[165]	[603]	6	hSpCas9	negative selection	2254490
109694643	109694666	4	-	24336569	HL60	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.32028309186649784	[448]	[760]	-3	hSpCas9	negative selection	2254491
109694654	109694677	4	+	24336569	HL60	viability	GAAGACACACACAAAGCAATCGG	CASP6	ENSG00000138794	0.6102584004110869	[1327]	[4289]	5	hSpCas9	negative selection	2254492
109694665	109694688	4	+	24336569	HL60	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	-0.44258605438045995	[568]	[885]	-4	hSpCas9	negative selection	2254493
109703379	109703402	4	-	24336569	HL60	viability	GCTGCAATGAGCTCGGCCTCGGG	CASP6	ENSG00000138794	-0.14109381526723622	[530]	[1018]	-1	hSpCas9	negative selection	2254494
109703386	109703409	4	-	24336569	HL60	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	-0.08737275751967166	[366]	[730]	0	hSpCas9	negative selection	2254495
109694574	109694597	4	-	24336569	KBM7	viability	ACATTAACTGGCTTGTTCAAAGG	CASP6	ENSG00000138794	-0.7751538545773871	[383]	[611]	-5	hSpCas9	negative selection	2321663
109694586	109694609	4	-	24336569	KBM7	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	1.1594770750228902	[215]	[1315]	8	hSpCas9	negative selection	2321664
109694626	109694649	4	+	24336569	KBM7	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.38053428567551884	[344]	[1224]	3	hSpCas9	negative selection	2321665
109694632	109694655	4	+	24336569	KBM7	viability	GATTGCCTTCGCCATGGCTCAGG	CASP6	ENSG00000138794	0.7045658874519525	[253]	[1128]	6	hSpCas9	negative selection	2321666
109694637	109694660	4	-	24336569	KBM7	viability	GTCTTCCTGAGCCATGGCGAAGG	CASP6	ENSG00000138794	-0.923028212523548	[316]	[455]	-6	hSpCas9	negative selection	2321667
109694643	109694666	4	-	24336569	KBM7	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.352261671851415	[329]	[1148]	3	hSpCas9	negative selection	2321668
109694654	109694677	4	+	24336569	KBM7	viability	GAAGACACACACAAAGCAATCGG	CASP6	ENSG00000138794	0.40889349207341263	[1253]	[4540]	4	hSpCas9	negative selection	2321669
109694665	109694688	4	+	24336569	KBM7	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.38555652911111177	[411]	[1467]	3	hSpCas9	negative selection	2321670
109703379	109703402	4	-	24336569	KBM7	viability	GCTGCAATGAGCTCGGCCTCGGG	CASP6	ENSG00000138794	0.3263433353068136	[342]	[1172]	3	hSpCas9	negative selection	2321671
109703386	109703409	4	-	24336569	KBM7	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.5073329139225794	[259]	[1007]	4	hSpCas9	negative selection	2321672
109703367	109703391	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CTCGGCCTCGGGGCTCCGCAGGGG	CASP6	ENSG00000138794	-0.8341431949186205	[5289,3601,4635]	[0,0,0]	-7	hSpCas9	positive selection	2380657
109703359	109703381	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GGGCTCCGCAGGGGGCACCCGG	CASP6	ENSG00000138794	0.8700837947161426	[1767,1560,833]	[0,0,0]	3	hSpCas9	positive selection	2380658
109694637	109694661	4	-	24717434	HeLa	essential genes for diphteria toxin toxicity	TGTCTTCCTGAGCCATGGCGAAGG	CASP6	ENSG00000138794	-1.3027206280417407	[7006,5224,6463]	[0,0,0]	-9	hSpCas9	positive selection	2380659
109703367	109703391	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTCGGCCTCGGGGCTCCGCAGGGG	CASP6	ENSG00000138794	3.1358194361227376	[5289,3601,4635]	[16,28,0]	6	hSpCas9	positive selection	2381798
109703367	109703391	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTCGGCCTCGGGGCTCCGCAGGGG	CASP6	ENSG00000138794	3.1358194361227376	[5289,3601,4635]	[16,28,0]	6	hSpCas9	positive selection	2381799
109703367	109703391	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTCGGCCTCGGGGCTCCGCAGGGG	CASP6	ENSG00000138794	3.1358194361227376	[5289,3601,4635]	[16,28,0]	6	hSpCas9	positive selection	2381800
109703359	109703381	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GGGCTCCGCAGGGGGCACCCGG	CASP6	ENSG00000138794	0.8685767216338908	[1767,1560,833]	[0,0,0]	2	hSpCas9	positive selection	2381801
109703359	109703381	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GGGCTCCGCAGGGGGCACCCGG	CASP6	ENSG00000138794	0.8685767216338908	[1767,1560,833]	[0,0,0]	2	hSpCas9	positive selection	2381802
109703359	109703381	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GGGCTCCGCAGGGGGCACCCGG	CASP6	ENSG00000138794	0.8685767216338908	[1767,1560,833]	[0,0,0]	2	hSpCas9	positive selection	2381803
109694637	109694661	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGTCTTCCTGAGCCATGGCGAAGG	CASP6	ENSG00000138794	2.470138985569597	[7006,5224,6463]	[0,38,0]	5	hSpCas9	positive selection	2381804
109694637	109694661	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGTCTTCCTGAGCCATGGCGAAGG	CASP6	ENSG00000138794	2.470138985569597	[7006,5224,6463]	[0,38,0]	5	hSpCas9	positive selection	2381805
109694637	109694661	4	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	TGTCTTCCTGAGCCATGGCGAAGG	CASP6	ENSG00000138794	2.470138985569597	[7006,5224,6463]	[0,38,0]	5	hSpCas9	positive selection	2381806
109703565	109703588	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGAGCTTTAACTCTGGGAAGG	CASP6	ENSG00000138794	2.82657450085379	[0,0]	[1,0]	8	dCas9-VP64	positive selection	2413036
109694873	109694896	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCACTCCAGCCCTGG	CASP6	ENSG00000138794	0.5268875283082193	[1,6]	[1,0]	2	dCas9-VP64	positive selection	2458634
109703565	109703588	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGAGCTTTAACTCTGGGAAGG	CASP6	ENSG00000138794	1.0049061711866196	[322,100]	[61,213]	6	dCas9-VP64	positive selection	2508291
109694873	109694896	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCACTCCAGCCCTGG	CASP6	ENSG00000138794	1.3449939631950025	[38,32]	[23,34]	7	dCas9-VP64	positive selection	2553889
109694522	109694545	4	+	27013184	SW480	treatment with recombinant TRAIL	TACCTGAATGATAAATATCTTGG	CASP6	ENSG00000138794	-1.193519630061216	[443,511]	[75,108]	-5	hSpCas9	positive selection	2960636
109697605	109697628	4	+	27013184	SW480	treatment with recombinant TRAIL	GTAGATAAAACTACTACCTGCGG	CASP6	ENSG00000138794	-2.660423973141243	[16,43]	[1,1]	-8	hSpCas9	positive selection	2960637
109694523	109694546	4	+	27013184	SW480	treatment with recombinant TRAIL	ACCTGAATGATAAATATCTTGGG	CASP6	ENSG00000138794	0.879878702292086	[955,1301]	[807,992]	4	hSpCas9	positive selection	2960638
109697606	109697629	4	+	27013184	SW480	treatment with recombinant TRAIL	TAGATAAAACTACTACCTGCGGG	CASP6	ENSG00000138794	1.2714160294582557	[146,148]	[66,277]	6	hSpCas9	positive selection	2960639
109694574	109694597	4	-	27013184	SW480	treatment with recombinant TRAIL	ACATTAACTGGCTTGTTCAAAGG	CASP6	ENSG00000138794	1.891734206076129	[83,142]	[35,378]	8	hSpCas9	positive selection	2960640
109697660	109697683	4	-	27013184	SW480	treatment with recombinant TRAIL	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	-0.46381465670779953	[129,105]	[54,11]	-2	hSpCas9	positive selection	2960641
109694586	109694609	4	-	27013184	SW480	treatment with recombinant TRAIL	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.19364316426819805	[57,203]	[1,110]	-1	hSpCas9	positive selection	2960642
109697681	109697704	4	-	27013184	SW480	treatment with recombinant TRAIL	TCAATCATGAGAGGTTCTTTTGG	CASP6	ENSG00000138794	1.126452996050044	[61,87]	[102,21]	5	hSpCas9	positive selection	2960643
109694637	109694660	4	-	27013184	SW480	treatment with recombinant TRAIL	GTCTTCCTGAGCCATGGCGAAGG	CASP6	ENSG00000138794	0.8477165213905788	[62,164]	[51,131]	4	hSpCas9	positive selection	2960644
109697690	109697713	4	-	27013184	SW480	treatment with recombinant TRAIL	CTTTAATCTTCAATCATGAGAGG	CASP6	ENSG00000138794	1.583922041742623	[1,1]	[2,1]	7	hSpCas9	positive selection	2960645
109697752	109697775	4	-	27013184	SW480	treatment with recombinant TRAIL	TAACAGAGAAATGTTTGATCCGG	CASP6	ENSG00000138794	1.365736738999882	[98,61]	[66,125]	6	hSpCas9	positive selection	2960646
109690916	109690939	4	-	27013184	SW480	treatment with recombinant TRAIL	GGACACCAACATAACTGAGGTGG	CASP6	ENSG00000138794	2.971575002353804	[61,212]	[353,568]	9	hSpCas9	positive selection	2960647
109690919	109690942	4	-	27013184	SW480	treatment with recombinant TRAIL	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	2.274688948023032	[4526,5001]	[11513,7614]	8	hSpCas9	positive selection	2960648
109690884	109690907	4	+	27013184	SW480	treatment with recombinant TRAIL	TCCAGCAGGCAGCGTGTAAACGG	CASP6	ENSG00000138794	-0.6564994201070395	[922,854]	[230,262]	-3	hSpCas9	positive selection	2960649
109694536	109694559	4	+	27013184	SW480	treatment with recombinant TRAIL	ATATCTTGGGTTTTCCAACCAGG	CASP6	ENSG00000138794	-0.27781660857784596	[137,56]	[16,62]	-1	hSpCas9	positive selection	2960650
109697630	109697653	4	+	27013184	SW480	treatment with recombinant TRAIL	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	2.2090247975505823	[89,93]	[91,312]	8	hSpCas9	positive selection	2960651
109690967	109690990	4	-	27013184	SW480	treatment with recombinant TRAIL	CGATGTGCCAGTCATTCCTTTGG	CASP6	ENSG00000138794	-0.6504794251396371	[505,777]	[173,171]	-3	hSpCas9	positive selection	2960652
109690911	109690934	4	+	27013184	SW480	treatment with recombinant TRAIL	TGCATCCACCTCAGTTATGTTGG	CASP6	ENSG00000138794	0.6665579049446393	[357,547]	[209,438]	3	hSpCas9	positive selection	2960653
109694626	109694649	4	+	27013184	SW480	treatment with recombinant TRAIL	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.0409792754163787	[18,43]	[7,53]	5	hSpCas9	positive selection	2960654
109694632	109694655	4	+	27013184	SW480	treatment with recombinant TRAIL	GATTGCCTTCGCCATGGCTCAGG	CASP6	ENSG00000138794	-0.968520898504482	[346,216]	[67,56]	-4	hSpCas9	positive selection	2960655
109690960	109690983	4	+	27013184	SW480	treatment with recombinant TRAIL	ACTACATCCAAAGGAATGACTGG	CASP6	ENSG00000138794	0.1053370904164681	[467,606]	[322,137]	0	hSpCas9	positive selection	2960656
109694665	109694688	4	+	27013184	SW480	treatment with recombinant TRAIL	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	-0.3748479197767629	[495,457]	[155,163]	-2	hSpCas9	positive selection	2960657
109690973	109690996	4	+	27013184	SW480	treatment with recombinant TRAIL	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	-0.7423846000882905	[848,960]	[291,146]	-3	hSpCas9	positive selection	2960658
109694687	109694710	4	+	27013184	SW480	treatment with recombinant TRAIL	GCTAACAGTTGACACTATAAAGG	CASP6	ENSG00000138794	0.4610861772378625	[1,4]	[1,1]	2	hSpCas9	positive selection	2960659
109697621	109697644	4	-	27013184	SW480	treatment with recombinant TRAIL	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	3.050831049507297	[19,10]	[67,40]	9	hSpCas9	positive selection	2960660
109694524	109694547	4	-	27013184	SW480	treatment with recombinant TRAIL	ACCCAAGATATTTATCATTCAGG	CASP6	ENSG00000138794	-1.302858129563055	[340,460]	[29,124]	-6	hSpCas9	positive selection	2960661
109697655	109697678	4	-	27013184	SW480	treatment with recombinant TRAIL	TTAACACTGCCAGAAAGGCGGGG	CASP6	ENSG00000138794	2.1794448361486745	[120,186]	[239,373]	8	hSpCas9	positive selection	2960662
109694550	109694573	4	-	27013184	SW480	treatment with recombinant TRAIL	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.8394668199033181	[355,329]	[195,364]	4	hSpCas9	positive selection	2960663
109697656	109697679	4	-	27013184	SW480	treatment with recombinant TRAIL	CTTAACACTGCCAGAAAGGCGGG	CASP6	ENSG00000138794	-0.49305949224147694	[237,424]	[134,47]	-2	hSpCas9	positive selection	2960664
109694554	109694577	4	-	27013184	SW480	treatment with recombinant TRAIL	AGGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	1.6886153845717644	[22,30]	[34,39]	7	hSpCas9	positive selection	2960665
109694666	109694689	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.6913327194404001	[3,3]	[3,5]	9	hSpCas9	positive selection	2976423
109703386	109703409	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.3793837503320732	[5,5]	[4,6]	7	hSpCas9	positive selection	2976424
109703364	109703387	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGCCCCCTGCGGAGCCCCGAGG	CASP6	ENSG00000138794	1.1693899835870094	[1,1]	[2,5]	9	hSpCas9	positive selection	2976425
109694643	109694666	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.06004029005316762	[3,3]	[4,1]	-1	hSpCas9	positive selection	2976426
109694666	109694689	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	-0.1339633211047208	[3,3]	[3,0]	-2	hSpCas9	positive selection	3044281
109703386	109703409	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.1412275758554818	[5,5]	[5,3]	2	hSpCas9	positive selection	3044282
109703364	109703387	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGCCCCCTGCGGAGCCCCGAGG	CASP6	ENSG00000138794	1.0932617259338615	[1,1]	[0,3]	9	hSpCas9	positive selection	3044283
109694643	109694666	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.00922916139014901	[3,3]	[2,2]	0	hSpCas9	positive selection	3044284
109698299	109698322		-	24336571	A375	resistance to PLX after 7 days	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.16660925192680764	[4,5]	[5,5]	5	hSpCas9	positive selection	3160741
109694626	109694649		+	24336571	A375	resistance to PLX after 7 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.16141761844329072	[26,25]	[24,20]	-5	hSpCas9	positive selection	3160742
109698290	109698313		+	24336571	A375	resistance to PLX after 7 days	ACAGCTTTACCTTTTATAGAAGG	CASP6	ENSG00000138794	-0.3750901732429801	[3,2]	[1,2]	-9	hSpCas9	positive selection	3160743
109694586	109694609		-	24336571	A375	resistance to PLX after 7 days	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.5286145125244543	[8,8]	[4,6]	-9	hSpCas9	positive selection	3160744
109690884	109690907		+	24336571	A375	resistance to PLX after 7 days	TCCAGCAGGCAGCGTGTAAACGG	CASP6	ENSG00000138794	-0.21362859549670798	[7,7]	[6,5]	-6	hSpCas9	positive selection	3160746
109690885	109690908		-	24336571	A375	resistance to PLX after 7 days	TCCGTTTACACGCTGCCTGCTGG	CASP6	ENSG00000138794	0.042533388157560914	[31,33]	[30,36]	1	hSpCas9	positive selection	3160747
109698299	109698322		-	24336571	A375	resistance to PLX after 14 days	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.5534269239559275	[6,3]	[3,3]	5	hSpCas9	positive selection	3218534
109694626	109694649		+	24336571	A375	resistance to PLX after 14 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.33649495764895065	[20,33]	[14,16]	3	hSpCas9	positive selection	3218535
109698290	109698313		+	24336571	A375	resistance to PLX after 14 days	ACAGCTTTACCTTTTATAGAAGG	CASP6	ENSG00000138794	0.6551926845909015	[2,1]	[1,1]	6	hSpCas9	positive selection	3218536
109694586	109694609		-	24336571	A375	resistance to PLX after 14 days	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.9459981648573018	[14,6]	[1,1]	-9	hSpCas9	positive selection	3218537
109690884	109690907		+	24336571	A375	resistance to PLX after 14 days	TCCAGCAGGCAGCGTGTAAACGG	CASP6	ENSG00000138794	1.1560773188000844	[11,8]	[8,11]	8	hSpCas9	positive selection	3218539
109690885	109690908		-	24336571	A375	resistance to PLX after 14 days	TCCGTTTACACGCTGCCTGCTGG	CASP6	ENSG00000138794	-0.59624151698696	[33,34]	[10,9]	-7	hSpCas9	positive selection	3218540
109698299	109698322		-	24336571	A375	viability after 7 days	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	-0.21569198275988077	[6]	[4,5]	-3	hSpCas9	negative selection	3276327
109694626	109694649		+	24336571	A375	viability after 7 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.1672719826243363	[30]	[26,25]	-2	hSpCas9	negative selection	3276328
109698290	109698313		+	24336571	A375	viability after 7 days	ACAGCTTTACCTTTTATAGAAGG	CASP6	ENSG00000138794	-0.6085809058856755	[5]	[3,2]	-7	hSpCas9	negative selection	3276329
109694586	109694609		-	24336571	A375	viability after 7 days	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.7566788660291103	[16]	[8,8]	-8	hSpCas9	negative selection	3276330
109690884	109690907		+	24336571	A375	viability after 7 days	TCCAGCAGGCAGCGTGTAAACGG	CASP6	ENSG00000138794	0.4540799168167581	[5]	[7,7]	7	hSpCas9	negative selection	3276332
109690885	109690908		-	24336571	A375	viability after 7 days	TCCGTTTACACGCTGCCTGCTGG	CASP6	ENSG00000138794	0.18202454628767684	[30]	[31,33]	2	hSpCas9	negative selection	3276333
109698299	109698322		-	24336571	A375	viability after 14 days	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	-0.11634469579539852	[6]	[6,3]	-1	hSpCas9	negative selection	3334120
109694626	109694649		+	24336571	A375	viability after 14 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.061875479146960455	[30]	[20,33]	0	hSpCas9	negative selection	3334121
109698290	109698313		+	24336571	A375	viability after 14 days	ACAGCTTTACCTTTTATAGAAGG	CASP6	ENSG00000138794	-1.1670007565456773	[5]	[2,1]	-9	hSpCas9	negative selection	3334122
109694586	109694609		-	24336571	A375	viability after 14 days	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.4717199611704159	[16]	[14,6]	-5	hSpCas9	negative selection	3334123
109690884	109690907		+	24336571	A375	viability after 14 days	TCCAGCAGGCAGCGTGTAAACGG	CASP6	ENSG00000138794	0.905005523005224	[5]	[11,8]	9	hSpCas9	negative selection	3334125
109690885	109690908		-	24336571	A375	viability after 14 days	TCCGTTTACACGCTGCCTGCTGG	CASP6	ENSG00000138794	0.2640200996817179	[30]	[33,34]	3	hSpCas9	negative selection	3334126
109697621	109697644	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	1.241355524871788	[96,31]	[0,0]	5	hSpCas9	positive selection	3341130
109697630	109697653	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.21043914977450548	[179,173]	[0,0]	-1	hSpCas9	positive selection	3341131
109694626	109694649	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.629685043460007	[80,116]	[0,0]	3	hSpCas9	positive selection	3341132
109694586	109694609	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.9905396707509337	[76,76]	[0,0]	4	hSpCas9	positive selection	3360378
109696410	109696433	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	-0.3201026165899134	[190,190]	[0,0]	-2	hSpCas9	positive selection	3360379
109698299	109698322	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	-0.9521271541831147	[295,295]	[0,0]	-6	hSpCas9	positive selection	3360380
109694665	109694688	4	+	26780180	HT29	viability (Avana library 4 designs)	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	1.28453884468021	[]	[]	5	hSpCas9	negative selection	3412704
109703386	109703409	4	-	26780180	HT29	viability (Avana library 4 designs)	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	-0.0653010817617133	[]	[]	-1	hSpCas9	negative selection	3412705
109703363	109703386	4	+	26780180	HT29	viability (Avana library 4 designs)	GTGCCCCCTGCGGAGCCCCGAGG	CASP6	ENSG00000138794	1.95477787313335	[]	[]	7	hSpCas9	negative selection	3412706
109694643	109694666	4	-	26780180	HT29	viability (Avana library 4 designs)	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.768980098124665	[]	[]	3	hSpCas9	negative selection	3412707
109694643	109694666	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	1.78286116128034	[]	[]	2	hSpCas9	negative selection	3488304
109703363	109703386	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTGCCCCCTGCGGAGCCCCGAGG	CASP6	ENSG00000138794	6.10213426365562	[]	[]	9	hSpCas9	negative selection	3488305
109694665	109694688	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	4.00370796370424	[]	[]	6	hSpCas9	negative selection	3488306
109703386	109703409	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	4.13640494959369	[]	[]	6	hSpCas9	negative selection	3488307
109690919	109690942	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	-0.327714442760532	[]	[]	0	hSpCas9	negative selection	3488308
109690999	109691022	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	3.51530309545892	[]	[]	5	hSpCas9	negative selection	3488309
109694643	109694666	4	-	26780180	A375	viability (Avana lentiGuide)	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	8.85265162566528	[]	[]	6	hSpCas9	negative selection	3596963
109703363	109703386	4	+	26780180	A375	viability (Avana lentiGuide)	GTGCCCCCTGCGGAGCCCCGAGG	CASP6	ENSG00000138794	-4.62664327708417	[]	[]	-7	hSpCas9	negative selection	3596964
109694665	109694688	4	+	26780180	A375	viability (Avana lentiGuide)	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	-3.00940039122834	[]	[]	-5	hSpCas9	negative selection	3596965
109703386	109703409	4	-	26780180	A375	viability (Avana lentiGuide)	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.136404353587569	[]	[]	0	hSpCas9	negative selection	3596966
109690919	109690942	4	-	26780180	A375	viability (Avana lentiGuide)	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	7.18819514478898	[]	[]	5	hSpCas9	negative selection	3596967
109690999	109691022	4	-	26780180	A375	viability (Avana lentiGuide)	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	4.56438294022711	[]	[]	4	hSpCas9	negative selection	3596968
109694643	109694666	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.04993004457124025	[5]	[5,4]	-1	hSpCas9	positive selection	3705622
109703363	109703386	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGCCCCCTGCGGAGCCCCGAGG	CASP6	ENSG00000138794	0.2319536489633559	[2]	[4,2]	6	hSpCas9	positive selection	3705623
109694665	109694688	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.14333538462099163	[3]	[4,3]	4	hSpCas9	positive selection	3705624
109703386	109703409	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.32801237725113586	[5]	[7,7]	8	hSpCas9	positive selection	3705625
109690919	109690942	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.19955281802760094	[4]	[4,4]	5	hSpCas9	positive selection	3705626
109690999	109691022	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.13780292694254886	[6]	[7,6]	3	hSpCas9	positive selection	3705627
109694643	109694666	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.09271051804970226	[5]	[3,4]	-1	hSpCas9	positive selection	3814229
109703363	109703386	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGCCCCCTGCGGAGCCCCGAGG	CASP6	ENSG00000138794	-0.5895459589174965	[4]	[1,2]	-6	hSpCas9	positive selection	3814230
109694665	109694688	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.2045490545453295	[5]	[6,3]	5	hSpCas9	positive selection	3814231
109703386	109703409	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.2865046654560577	[7]	[7,7]	7	hSpCas9	positive selection	3814232
109690919	109690942	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.20046189643202983	[5]	[4,5]	5	hSpCas9	positive selection	3814233
109690999	109691022	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.0996365173433986	[6]	[6,4]	2	hSpCas9	positive selection	3814234
109698299	109698322	4	-	26780180	A375	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	1.02589753987282	[]	[]	5	hSpCas9	negative selection	3922529
109694626	109694649	4	+	26780180	A375	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.454416347659345	[]	[]	1	hSpCas9	negative selection	3922530
109697630	109697653	4	+	26780180	A375	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	1.21333063569362	[]	[]	6	hSpCas9	negative selection	3922531
109696410	109696433	4	-	26780180	A375	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.328025877486161	[]	[]	0	hSpCas9	negative selection	3922532
109697621	109697644	4	-	26780180	A375	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	1.69241837158007	[]	[]	9	hSpCas9	negative selection	3922533
109694586	109694609	4	-	26780180	A375	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.833468583974218	[]	[]	3	hSpCas9	negative selection	3922534
109698299	109698322	4	-	26780180	HT29	viability (GeCKOv2 library)	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.139420553995798	[]	[]	0	hSpCas9	negative selection	4030495
109694626	109694649	4	+	26780180	HT29	viability (GeCKOv2 library)	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.322538491130133	[]	[]	0	hSpCas9	negative selection	4030496
109697630	109697653	4	+	26780180	HT29	viability (GeCKOv2 library)	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	1.38861373791309	[]	[]	7	hSpCas9	negative selection	4030497
109696410	109696433	4	-	26780180	HT29	viability (GeCKOv2 library)	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.713209412303928	[]	[]	2	hSpCas9	negative selection	4030498
109697621	109697644	4	-	26780180	HT29	viability (GeCKOv2 library)	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	1.95993568732556	[]	[]	9	hSpCas9	negative selection	4030499
109694586	109694609	4	-	26780180	HT29	viability (GeCKOv2 library)	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	1.54114544330618	[]	[]	7	hSpCas9	negative selection	4030500
109698299	109698322	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.019309664195333254	[2]	[1,1]	0	hSpCas9	positive selection	4188834
109694626	109694649	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.653531262907318	[4]	[6,3]	9	hSpCas9	positive selection	4188835
109698290	109698313	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAGCTTTACCTTTTATAGAAGG	CASP6	ENSG00000138794	-0.10810294765420703	[0]	[0,0]	-3	hSpCas9	positive selection	4188836
109694586	109694609	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.29446124945284646	[2]	[1,0]	-6	hSpCas9	positive selection	4188837
109690884	109690907	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCAGCAGGCAGCGTGTAAACGG	CASP6	ENSG00000138794	0.4325862019995357	[2]	[2,3]	8	hSpCas9	positive selection	4188839
109690885	109690908	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCGTTTACACGCTGCCTGCTGG	CASP6	ENSG00000138794	-0.012710968048551513	[4]	[2,3]	0	hSpCas9	positive selection	4188840
109698299	109698322	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	-0.07673591535199253	[2]	[0,2,0,0]	-1	hSpCas9	positive selection	4252856
109694626	109694649	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.1274690849423024	[5]	[6,2,3,5]	8	hSpCas9	positive selection	4252857
109698290	109698313	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAGCTTTACCTTTTATAGAAGG	CASP6	ENSG00000138794	0.7473023697162793	[1]	[0,3,0,0]	5	hSpCas9	positive selection	4252858
109694586	109694609	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.9237064600929494	[4]	[3,2,4,3]	6	hSpCas9	positive selection	4252859
109690884	109690907	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCAGCAGGCAGCGTGTAAACGG	CASP6	ENSG00000138794	1.1602809340738387	[2]	[4,2,1,2]	8	hSpCas9	positive selection	4252861
109690885	109690908	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCGTTTACACGCTGCCTGCTGG	CASP6	ENSG00000138794	0.8343978723007581	[4]	[2,4,1,4]	5	hSpCas9	positive selection	4252862
109697621	109697644	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.02754504090147661	[2]	[2,1]	0	hSpCas9	positive selection	4261018
109697630	109697653	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	0.18089862339032914	[4]	[3,3]	3	hSpCas9	positive selection	4261019
109694626	109694649	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.40733809037232716	[2]	[2,2]	8	hSpCas9	positive selection	4261020
109694586	109694609	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.4611038568988406	[2]	[3,1]	8	hSpCas9	positive selection	4325296
109696410	109696433	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.805403126347972	[2]	[3,5]	9	hSpCas9	positive selection	4325297
109698299	109698322	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.12336626889996724	[3]	[3,2]	2	hSpCas9	positive selection	4325298
109690888	109690910	4	+	27760321	OCIAML3	viability	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.3602233499816364	[660,566]	[329,428]	-4	hSpCas9	negative selection	4385817
109690952	109690974	4	+	27760321	OCIAML3	viability	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	0.8352143462260226	[30,9]	[10,48]	8	hSpCas9	negative selection	4385818
109690974	109690996	4	+	27760321	OCIAML3	viability	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.5743776572172506	[743,601]	[647,950]	6	hSpCas9	negative selection	4385819
109694554	109694576	4	-	27760321	OCIAML3	viability	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	0.5987886485475216	[531,443]	[582,565]	7	hSpCas9	negative selection	4385820
109694586	109694608	4	-	27760321	OCIAML3	viability	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.4799975362454876	[103,77]	[64,141]	6	hSpCas9	negative selection	4385821
109690888	109690910	4	+	27760321	OCIAML2	viability	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.41137418550557736	[660,566]	[548,802]	5	hSpCas9	negative selection	4469280
109690952	109690974	4	+	27760321	OCIAML2	viability	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	0.7725851464104005	[30,9]	[34,16]	9	hSpCas9	negative selection	4469281
109690974	109690996	4	+	27760321	OCIAML2	viability	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	-0.01344710537346172	[743,601]	[403,710]	0	hSpCas9	negative selection	4469282
109694554	109694576	4	-	27760321	OCIAML2	viability	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	-0.17683013500279512	[531,443]	[314,390]	-2	hSpCas9	negative selection	4469283
109694586	109694608	4	-	27760321	OCIAML2	viability	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.5404742685403874	[103,77]	[22,85]	-6	hSpCas9	negative selection	4469284
109690888	109690910	4	+	27760321	MV411	viability	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.17197683096012928	[660,566]	[341,624]	1	hSpCas9	negative selection	4552743
109690952	109690974	4	+	27760321	MV411	viability	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	-0.8928029610418609	[30,9]	[10,0]	-5	hSpCas9	negative selection	4552744
109690974	109690996	4	+	27760321	MV411	viability	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	1.3128027830205697	[743,601]	[797,1546]	8	hSpCas9	negative selection	4552745
109694554	109694576	4	-	27760321	MV411	viability	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	1.041186659916768	[531,443]	[161,1407]	7	hSpCas9	negative selection	4552746
109694586	109694608	4	-	27760321	MV411	viability	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	1.4047738506095433	[103,77]	[227,51]	8	hSpCas9	negative selection	4552747
109690888	109690910	4	+	27760321	HL60	viability	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.03030522381169687	[660,566]	[416,609]	0	hSpCas9	negative selection	4636206
109690952	109690974	4	+	27760321	HL60	viability	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	0.10723001696858958	[30,9]	[11,22]	1	hSpCas9	negative selection	4636207
109690974	109690996	4	+	27760321	HL60	viability	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.28338562729903194	[743,601]	[664,665]	3	hSpCas9	negative selection	4636208
109694554	109694576	4	-	27760321	HL60	viability	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	-0.05436322064735287	[531,443]	[342,423]	0	hSpCas9	negative selection	4636209
109694586	109694608	4	-	27760321	HL60	viability	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-2.5428558531451606	[103,77]	[0,24]	-9	hSpCas9	negative selection	4636210
109690888	109690910	4	+	27760321	HT1080	viability	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.18313858105184133	[566,442]	[33,333]	-1	hSpCas9	negative selection	4719669
109690952	109690974	4	+	27760321	HT1080	viability	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	-1.8443172389209588	[9,7]	[0,0]	-6	hSpCas9	negative selection	4719670
109690974	109690996	4	+	27760321	HT1080	viability	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	-2.0189437152816776	[601,469]	[24,82]	-6	hSpCas9	negative selection	4719671
109694554	109694576	4	-	27760321	HT1080	viability	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	0.445334660088462	[443,346]	[183,247]	2	hSpCas9	negative selection	4719672
109694586	109694608	4	-	27760321	HT1080	viability	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	1.87954193500275	[77,60]	[88,115]	8	hSpCas9	negative selection	4719673
109690888	109690910	4	+	27760321	HT29	viability after 7 days	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.15768084375725255	[566,442]	[802,460,912]	2	hSpCas9	negative selection	4803132
109690952	109690974	4	+	27760321	HT29	viability after 7 days	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	0.6872409454554607	[9,7]	[16,28,9]	9	hSpCas9	negative selection	4803133
109690974	109690996	4	+	27760321	HT29	viability after 7 days	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	-0.2201586887360087	[601,469]	[901,379,537]	-3	hSpCas9	negative selection	4803134
109694554	109694576	4	-	27760321	HT29	viability after 7 days	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	0.4769649738604408	[443,346]	[847,638,656]	7	hSpCas9	negative selection	4803135
109694586	109694608	4	-	27760321	HT29	viability after 7 days	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.6325027538014738	[77,60]	[88,51,36]	-7	hSpCas9	negative selection	4803136
109690888	109690910	4	+	27760321	HT29	viability after 25 days	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.5270927441782465	[566,442]	[853,758,884]	6	hSpCas9	negative selection	4886595
109690952	109690974	4	+	27760321	HT29	viability after 25 days	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	0.9256903391010312	[9,7]	[23,0,34]	9	hSpCas9	negative selection	4886596
109690974	109690996	4	+	27760321	HT29	viability after 25 days	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.13620509647737034	[601,469]	[602,686,739]	1	hSpCas9	negative selection	4886597
109694554	109694576	4	-	27760321	HT29	viability after 25 days	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	0.4759032071770638	[443,346]	[608,633,644]	5	hSpCas9	negative selection	4886598
109694586	109694608	4	-	27760321	HT29	viability after 25 days	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.2767493421918181	[77,60]	[125,9,156]	3	hSpCas9	negative selection	4886599
109690888	109690910	4	+	27760321	HT29	viability after 22 days	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.6687191126961698	[566,442]	[1083,881,812]	7	hSpCas9	negative selection	4970058
109690952	109690974	4	+	27760321	HT29	viability after 22 days	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	1.6133959725329103	[9,7]	[26,13,54]	9	hSpCas9	negative selection	4970059
109690974	109690996	4	+	27760321	HT29	viability after 22 days	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	-0.22435778505625592	[601,469]	[624,396,566]	-2	hSpCas9	negative selection	4970060
109694554	109694576	4	-	27760321	HT29	viability after 22 days	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	0.6279835209843461	[443,346]	[823,662,628]	7	hSpCas9	negative selection	4970061
109694586	109694608	4	-	27760321	HT29	viability after 22 days	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.987291039284854	[77,60]	[35,15,69]	-6	hSpCas9	negative selection	4970062
109690888	109690910	4	+	27760321	HT29	viability after 19 days	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.5026609866542072	[566,442]	[1308,301,891]	5	hSpCas9	negative selection	5053521
109690952	109690974	4	+	27760321	HT29	viability after 19 days	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	1.00388155264754	[9,7]	[15,10,33]	9	hSpCas9	negative selection	5053522
109690974	109690996	4	+	27760321	HT29	viability after 19 days	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.086584804590775	[601,469]	[790,523,651]	0	hSpCas9	negative selection	5053523
109694554	109694576	4	-	27760321	HT29	viability after 19 days	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	0.5104280235297534	[443,346]	[990,494,488]	5	hSpCas9	negative selection	5053524
109694586	109694608	4	-	27760321	HT29	viability after 19 days	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.604990120240485	[77,60]	[132,0,31]	-5	hSpCas9	negative selection	5053525
109690888	109690910	4	+	27760321	HT29	viability after 16 days	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.5648125159247668	[566,442]	[630,1061,788]	6	hSpCas9	negative selection	5136984
109690952	109690974	4	+	27760321	HT29	viability after 16 days	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	1.4634246906838775	[9,7]	[7,48,23]	9	hSpCas9	negative selection	5136985
109690974	109690996	4	+	27760321	HT29	viability after 16 days	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.034852659012196585	[601,469]	[691,625,531]	0	hSpCas9	negative selection	5136986
109694554	109694576	4	-	27760321	HT29	viability after 16 days	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	0.4476616947444403	[443,346]	[732,630,457]	5	hSpCas9	negative selection	5136987
109694586	109694608	4	-	27760321	HT29	viability after 16 days	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.7709320785736684	[77,60]	[221,113,70]	8	hSpCas9	negative selection	5136988
109690888	109690910	4	+	27760321	HT29	viability after 13 days	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.6900610109673122	[566,442]	[1211,831,799]	8	hSpCas9	negative selection	5220447
109690952	109690974	4	+	27760321	HT29	viability after 13 days	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	-0.13775826094896448	[9,7]	[0,25,1]	-2	hSpCas9	negative selection	5220448
109690974	109690996	4	+	27760321	HT29	viability after 13 days	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.10242584177166969	[601,469]	[937,532,538]	1	hSpCas9	negative selection	5220449
109694554	109694576	4	-	27760321	HT29	viability after 13 days	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	0.6995302244526339	[443,346]	[1015,596,628]	8	hSpCas9	negative selection	5220450
109694586	109694608	4	-	27760321	HT29	viability after 13 days	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.47707531888018306	[77,60]	[174,90,72]	6	hSpCas9	negative selection	5220451
109690888	109690910	4	+	27760321	HT29	viability after 10 days	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.22489181683810544	[566,442]	[968,799,449]	3	hSpCas9	negative selection	5303910
109690952	109690974	4	+	27760321	HT29	viability after 10 days	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	0.7891261367090676	[9,7]	[2,19,34]	9	hSpCas9	negative selection	5303911
109690974	109690996	4	+	27760321	HT29	viability after 10 days	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.19524437607748024	[601,469]	[769,953,583]	2	hSpCas9	negative selection	5303912
109694554	109694576	4	-	27760321	HT29	viability after 10 days	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	0.20207328491721285	[443,346]	[856,434,411]	2	hSpCas9	negative selection	5303913
109694586	109694608	4	-	27760321	HT29	viability after 10 days	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.05536942376893972	[77,60]	[80,153,18]	0	hSpCas9	negative selection	5303914
109690888	109690910	4	+	27760321	MOLM13	viability	GCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.9567049602620833	[660,566]	[564,759]	6	hSpCas9	negative selection	5387373
109690952	109690974	4	+	27760321	MOLM13	viability	GATTATCTACTACATCCAAAGG	CASP6	ENSG00000138794	0.5408824534103673	[30,9]	[33,0]	4	hSpCas9	negative selection	5387374
109690974	109690996	4	+	27760321	MOLM13	viability	AATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	-0.2717000729757866	[743,601]	[267,350]	-2	hSpCas9	negative selection	5387375
109694554	109694576	4	-	27760321	MOLM13	viability	GGAGACAAGTGTCACAGCCTGG	CASP6	ENSG00000138794	1.3616487492514355	[531,443]	[1314,184]	8	hSpCas9	negative selection	5387376
109694586	109694608	4	-	27760321	MOLM13	viability	TCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.490408611103492	[103,77]	[77,65]	3	hSpCas9	negative selection	5387377
109702993	109703016	4	+	27661255	K562	viability	GGGAACGCCAGGCCCGCGTGGGG	CASP6	ENSG00000138794	0.425293858375667	[532,699]	[690,629]	9	dCas9-KRAB	negative selection	5468215
109703051	109703074	4	+	27661255	K562	viability	GAAAGCGCTCATCGCCCCGGAGG	CASP6	ENSG00000138794	-0.24474710361606733	[778,790]	[534,523]	-6	dCas9-KRAB	negative selection	5468216
109703333	109703356	4	-	27661255	K562	viability	GTAGGCAGGGGGCGTCGACTGGG	CASP6	ENSG00000138794	0.3076789919174514	[907,956]	[980,869]	8	dCas9-KRAB	negative selection	5468217
109697621	109697644	4	-	27260156	BXPC3	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.14450520922663168	[295]	[255,314,219,332]	-3	hSpCas9	negative selection	5533478
109697630	109697653	4	+	27260156	BXPC3	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.37678670477261067	[996]	[975,623,761,838]	-7	hSpCas9	negative selection	5533479
109694626	109694649	4	+	27260156	BXPC3	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.34679275849513813	[314]	[400,437,432,398]	7	hSpCas9	negative selection	5533480
109694586	109694609	4	-	27260156	BXPC3	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.2135479592391789	[223]	[133,218,233,229]	-5	hSpCas9	negative selection	5597756
109696410	109696433	4	-	27260156	BXPC3	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.17187818312569586	[449]	[439,536,516,645]	4	hSpCas9	negative selection	5597757
109698299	109698322	4	-	27260156	BXPC3	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.15657820164506697	[659]	[725,655,816,900]	3	hSpCas9	negative selection	5597758
109697621	109697644	4	-	27260156	A673	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.21831366469945923	[295]	[255,319,348,288]	-5	hSpCas9	negative selection	5654729
109697630	109697653	4	+	27260156	A673	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.16563012277775324	[996]	[1180,1125,891,1081]	-4	hSpCas9	negative selection	5654730
109694626	109694649	4	+	27260156	A673	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.07402198957325212	[314]	[491,333,415,359]	1	hSpCas9	negative selection	5654731
109694586	109694609	4	-	27260156	A673	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.13852736154821976	[223]	[271,335,334,232]	3	hSpCas9	negative selection	5719007
109696410	109696433	4	-	27260156	A673	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	-0.035142769902495444	[449]	[608,491,401,621]	-1	hSpCas9	negative selection	5719008
109698299	109698322	4	-	27260156	A673	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.15951296434422235	[659]	[1074,797,931,749]	4	hSpCas9	negative selection	5719009
109697621	109697644	4	-	27260156	A375	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.1377153745102806	[295]	[432,275,335,217]	-2	hSpCas9	negative selection	5775980
109697630	109697653	4	+	27260156	A375	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.0931104663460316	[996]	[825,1276,1178,1102]	-1	hSpCas9	negative selection	5775981
109694626	109694649	4	+	27260156	A375	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.608961831112357	[314]	[468,613,613,552]	8	hSpCas9	negative selection	5775982
109694586	109694609	4	-	27260156	A375	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.5256356768596845	[223]	[310,439,298,453]	7	hSpCas9	negative selection	5840258
109696410	109696433	4	-	27260156	A375	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.3030621636749139	[449]	[662,868,634,475]	4	hSpCas9	negative selection	5840259
109698299	109698322	4	-	27260156	A375	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.4617877762980983	[659]	[1032,1021,1139,1043]	6	hSpCas9	negative selection	5840260
109697621	109697644	4	-	27260156	COLO741	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.031000152236600353	[295]	[363,356,431]	0	hSpCas9	negative selection	5897231
109697630	109697653	4	+	27260156	COLO741	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.1732615360522839	[996]	[1330,1133,951]	-4	hSpCas9	negative selection	5897232
109694626	109694649	4	+	27260156	COLO741	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.4077153701751003	[314]	[577,572,458]	8	hSpCas9	negative selection	5897233
109694586	109694609	4	-	27260156	COLO741	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.013763466137244107	[223]	[448,218,216]	0	hSpCas9	negative selection	5961509
109696410	109696433	4	-	27260156	COLO741	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.10572668357746952	[449]	[569,652,626]	2	hSpCas9	negative selection	5961510
109698299	109698322	4	-	27260156	COLO741	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.17166861607524198	[659]	[1108,974,788]	3	hSpCas9	negative selection	5961511
109697621	109697644	4	-	27260156	CAL120	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.09204281259547908	[295]	[419,238,387]	-1	hSpCas9	negative selection	6018482
109697630	109697653	4	+	27260156	CAL120	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	0.15149920043035503	[996]	[886,1759,1411]	2	hSpCas9	negative selection	6018483
109694626	109694649	4	+	27260156	CAL120	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.5411415060898838	[314]	[540,455,706]	7	hSpCas9	negative selection	6018484
109694586	109694609	4	-	27260156	CAL120	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.4940036168770876	[223]	[425,499,258]	7	hSpCas9	negative selection	6082760
109696410	109696433	4	-	27260156	CAL120	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.629687692533412	[449]	[1363,625,686]	8	hSpCas9	negative selection	6082761
109698299	109698322	4	-	27260156	CAL120	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.41034005274461083	[659]	[1214,1453,631]	6	hSpCas9	negative selection	6082762
109697621	109697644	4	-	27260156	CADOES1	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.585217200688092	[295]	[180,158,259,131]	-8	hSpCas9	negative selection	6139733
109697630	109697653	4	+	27260156	CADOES1	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.327780398192944	[996]	[726,607,803,818]	-5	hSpCas9	negative selection	6139734
109694626	109694649	4	+	27260156	CADOES1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.19328353715289542	[314]	[327,248,368,395]	3	hSpCas9	negative selection	6139735
109694586	109694609	4	-	27260156	CADOES1	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.1457947317492222	[223]	[291,258,238,127]	2	hSpCas9	negative selection	6204011
109696410	109696433	4	-	27260156	CADOES1	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.09047128240598434	[449]	[259,489,484,551]	1	hSpCas9	negative selection	6204012
109698299	109698322	4	-	27260156	CADOES1	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.2857250021879204	[659]	[671,709,893,715]	5	hSpCas9	negative selection	6204013
109697621	109697644	4	-	27260156	EWS502	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.2828979137508978	[295]	[282,229,221,294]	-5	hSpCas9	negative selection	6260984
109697630	109697653	4	+	27260156	EWS502	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.25317346915719574	[996]	[862,916,989,764]	-4	hSpCas9	negative selection	6260985
109694626	109694649	4	+	27260156	EWS502	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.2399661066884971	[314]	[502,275,410,374]	4	hSpCas9	negative selection	6260986
109694586	109694609	4	-	27260156	EWS502	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.3493511442112258	[223]	[156,164,198,230]	-6	hSpCas9	negative selection	6325262
109696410	109696433	4	-	27260156	EWS502	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.22313361127730408	[449]	[571,517,547,586]	4	hSpCas9	negative selection	6325263
109698299	109698322	4	-	27260156	EWS502	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.4335729165000738	[659]	[809,732,1024,1252]	7	hSpCas9	negative selection	6325264
109697621	109697644	4	-	27260156	EW8	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.05055109218584097	[295]	[289,294,104,263]	-1	hSpCas9	negative selection	6382235
109697630	109697653	4	+	27260156	EW8	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.19763657888270036	[996]	[866,805,477,721]	-4	hSpCas9	negative selection	6382236
109694626	109694649	4	+	27260156	EW8	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.2356232231915692	[314]	[460,220,323,208]	4	hSpCas9	negative selection	6382237
109694586	109694609	4	-	27260156	EW8	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.018779328171333987	[223]	[159,146,135,277]	0	hSpCas9	negative selection	6446513
109696410	109696433	4	-	27260156	EW8	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.6738652119478583	[449]	[581,453,344,982]	9	hSpCas9	negative selection	6446514
109698299	109698322	4	-	27260156	EW8	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.06930927253649533	[659]	[818,566,382,532]	1	hSpCas9	negative selection	6446515
109697621	109697644	4	-	27260156	CORL105	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.08792777116572337	[295]	[536,304,339,293]	1	hSpCas9	negative selection	6503486
109697630	109697653	4	+	27260156	CORL105	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.3828558442470945	[996]	[922,1043,882,726]	-6	hSpCas9	negative selection	6503487
109694626	109694649	4	+	27260156	CORL105	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.25757217128818366	[314]	[468,394,571,349]	5	hSpCas9	negative selection	6503488
109694586	109694609	4	-	27260156	CORL105	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.08026342653242469	[223]	[239,317,249,182]	-1	hSpCas9	negative selection	6567764
109696410	109696433	4	-	27260156	CORL105	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.06804715894757349	[449]	[878,544,392,378]	1	hSpCas9	negative selection	6567765
109698299	109698322	4	-	27260156	CORL105	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.27282459735154063	[659]	[956,815,1199,805]	5	hSpCas9	negative selection	6567766
109697621	109697644	4	-	27260156	HS294T	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.523397162332297	[295]	[79,62,89,86]	-6	hSpCas9	negative selection	6624737
109697630	109697653	4	+	27260156	HS294T	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.34407883382179005	[996]	[183,307,360,385]	-5	hSpCas9	negative selection	6624738
109694626	109694649	4	+	27260156	HS294T	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.19388448510156964	[314]	[96,151,63,112]	-3	hSpCas9	negative selection	6624739
109694586	109694609	4	-	27260156	HS294T	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.12989831708758182	[223]	[65,92,60,174]	1	hSpCas9	negative selection	6689015
109696410	109696433	4	-	27260156	HS294T	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.2198439009503495	[449]	[186,137,308,174]	3	hSpCas9	negative selection	6689016
109698299	109698322	4	-	27260156	HS294T	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	-0.08411606997903714	[659]	[199,220,258,295]	-1	hSpCas9	negative selection	6689017
109697621	109697644	4	-	27260156	HCC44	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.40648675477478924	[295]	[343,254,166,235]	-6	hSpCas9	negative selection	6745988
109697630	109697653	4	+	27260156	HCC44	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.08772966017504102	[996]	[1112,848,1183,1142]	-1	hSpCas9	negative selection	6745989
109694626	109694649	4	+	27260156	HCC44	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.4473189832129444	[314]	[499,391,566,507]	7	hSpCas9	negative selection	6745990
109694586	109694609	4	-	27260156	HCC44	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.3830504699566216	[223]	[311,293,382,341]	6	hSpCas9	negative selection	6810266
109696410	109696433	4	-	27260156	HCC44	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.37661888538847266	[449]	[765,505,796,624]	6	hSpCas9	negative selection	6810267
109698299	109698322	4	-	27260156	HCC44	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.2883420999908288	[659]	[782,685,1039,1163]	5	hSpCas9	negative selection	6810268
109697621	109697644	4	-	27260156	G402	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.27121636162422	[295]	[355,133,202,491]	-3	hSpCas9	negative selection	6867239
109697630	109697653	4	+	27260156	G402	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.3204391538367545	[996]	[1163,1220,725,830]	-4	hSpCas9	negative selection	6867240
109694626	109694649	4	+	27260156	G402	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.5058475986509381	[314]	[681,433,443,629]	6	hSpCas9	negative selection	6867241
109694586	109694609	4	-	27260156	G402	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.4738446782639769	[223]	[381,540,252,351]	6	hSpCas9	negative selection	6931517
109696410	109696433	4	-	27260156	G402	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.2080362179319893	[449]	[971,559,750,311]	2	hSpCas9	negative selection	6931518
109698299	109698322	4	-	27260156	G402	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.5184505015312176	[659]	[1474,948,1080,1139]	6	hSpCas9	negative selection	6931519
109697621	109697644	4	-	27260156	L33	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.25251228075568855	[295]	[182,171,133,179]	-5	hSpCas9	negative selection	6988490
109697630	109697653	4	+	27260156	L33	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.07360180863285848	[996]	[932,400,590,937]	-2	hSpCas9	negative selection	6988491
109694626	109694649	4	+	27260156	L33	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.21416047579653485	[314]	[345,150,265,324]	4	hSpCas9	negative selection	6988492
109694586	109694609	4	-	27260156	L33	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.14908460705549986	[223]	[145,103,111,230]	-3	hSpCas9	negative selection	7052768
109696410	109696433	4	-	27260156	L33	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	-0.053051578030719374	[449]	[508,138,248,487]	-1	hSpCas9	negative selection	7052769
109698299	109698322	4	-	27260156	L33	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.13355538934795552	[659]	[696,318,395,789]	3	hSpCas9	negative selection	7052770
109697621	109697644	4	-	27260156	K562	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.22477836156979103	[295]	[177,245,166,295]	-3	hSpCas9	negative selection	7109741
109697630	109697653	4	+	27260156	K562	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.1802129082666013	[996]	[782,909,840,612]	-2	hSpCas9	negative selection	7109742
109694626	109694649	4	+	27260156	K562	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.5347677332731551	[314]	[344,330,524,407]	6	hSpCas9	negative selection	7109743
109694586	109694609	4	-	27260156	K562	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.20747004375669287	[223]	[422,148,223,142]	2	hSpCas9	negative selection	7174019
109696410	109696433	4	-	27260156	K562	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	-0.11117141837283466	[449]	[458,423,333,280]	-1	hSpCas9	negative selection	7174020
109698299	109698322	4	-	27260156	K562	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.13448985485888332	[659]	[971,445,226,908]	1	hSpCas9	negative selection	7174021
109697621	109697644	4	-	27260156	HT29	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.00852980218680588	[295]	[381,363,321,376]	0	hSpCas9	negative selection	7230992
109697630	109697653	4	+	27260156	HT29	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.042486470355312056	[996]	[1130,1370,1178,1046]	-1	hSpCas9	negative selection	7230993
109694626	109694649	4	+	27260156	HT29	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.35283973378288397	[314]	[462,625,426,450]	7	hSpCas9	negative selection	7230994
109694586	109694609	4	-	27260156	HT29	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.28651416146613673	[223]	[372,361,239,353]	5	hSpCas9	negative selection	7295270
109696410	109696433	4	-	27260156	HT29	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.252773714126786	[449]	[762,758,597,516]	5	hSpCas9	negative selection	7295271
109698299	109698322	4	-	27260156	HT29	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.3175665803579766	[659]	[983,1182,959,892]	6	hSpCas9	negative selection	7295272
109697621	109697644	4	-	27260156	MHHES1	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.1195526084966807	[295]	[417,330,389,315]	2	hSpCas9	negative selection	7352243
109697630	109697653	4	+	27260156	MHHES1	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	0.07186598252739818	[996]	[908,1192,1369,1188]	1	hSpCas9	negative selection	7352244
109694626	109694649	4	+	27260156	MHHES1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.5377236685395487	[314]	[708,643,408,358]	8	hSpCas9	negative selection	7352245
109694586	109694609	4	-	27260156	MHHES1	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.21431855755057483	[223]	[198,240,273,163]	-4	hSpCas9	negative selection	7416521
109696410	109696433	4	-	27260156	MHHES1	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	-0.14469115091440965	[449]	[377,446,540,448]	-3	hSpCas9	negative selection	7416522
109698299	109698322	4	-	27260156	MHHES1	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.3787527330865049	[659]	[1094,1143,1038,669]	6	hSpCas9	negative selection	7416523
109697621	109697644	4	-	27260156	MEWO	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.20022046185711628	[295]	[208,212,294]	-4	hSpCas9	negative selection	7473494
109697630	109697653	4	+	27260156	MEWO	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.10788259744340489	[996]	[1019,737,868]	-2	hSpCas9	negative selection	7473495
109694626	109694649	4	+	27260156	MEWO	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.2132141074134929	[314]	[500,282,271]	4	hSpCas9	negative selection	7473496
109694586	109694609	4	-	27260156	MEWO	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.07730814837136624	[223]	[173,247,231]	1	hSpCas9	negative selection	7537772
109696410	109696433	4	-	27260156	MEWO	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.20793645709432435	[449]	[577,379,518]	4	hSpCas9	negative selection	7537773
109698299	109698322	4	-	27260156	MEWO	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.11138819240420217	[659]	[824,575,630]	2	hSpCas9	negative selection	7537774
109697621	109697644	4	-	27260156	LNCAPCLONEFGC	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.1606107896429465	[295]	[152,185,329,308]	-3	hSpCas9	negative selection	7594745
109697630	109697653	4	+	27260156	LNCAPCLONEFGC	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.24000089267239288	[996]	[926,574,745,816]	-4	hSpCas9	negative selection	7594746
109694626	109694649	4	+	27260156	LNCAPCLONEFGC	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.08514472173403798	[314]	[246,274,276,277]	-1	hSpCas9	negative selection	7594747
109694586	109694609	4	-	27260156	LNCAPCLONEFGC	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.20074941017861925	[223]	[249,260,303,125]	3	hSpCas9	negative selection	7659023
109696410	109696433	4	-	27260156	LNCAPCLONEFGC	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.007169052335102309	[449]	[288,267,718,419]	0	hSpCas9	negative selection	7659024
109698299	109698322	4	-	27260156	LNCAPCLONEFGC	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.28546240412535473	[659]	[728,716,775,699]	4	hSpCas9	negative selection	7659025
109697621	109697644	4	-	27260156	PANC0327	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.5516895059171041	[295]	[242,198,88,188]	-7	hSpCas9	negative selection	7715996
109697630	109697653	4	+	27260156	PANC0327	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	0.012223874241954258	[996]	[751,1041,603,1142]	0	hSpCas9	negative selection	7715997
109694626	109694649	4	+	27260156	PANC0327	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.21997408327493773	[314]	[268,372,417,232]	3	hSpCas9	negative selection	7715998
109694586	109694609	4	-	27260156	PANC0327	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.3060259389560499	[223]	[151,281,440,96]	4	hSpCas9	negative selection	7780274
109696410	109696433	4	-	27260156	PANC0327	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.3671147691848751	[449]	[316,335,1034,381]	5	hSpCas9	negative selection	7780275
109698299	109698322	4	-	27260156	PANC0327	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.5227013059390814	[659]	[1148,714,614,930]	7	hSpCas9	negative selection	7780276
109697621	109697644	4	-	27260156	NCIH2009	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.04733880033538029	[295]	[396,555,319]	0	hSpCas9	negative selection	7837247
109697630	109697653	4	+	27260156	NCIH2009	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.4780982826027813	[996]	[1719,709,715]	-6	hSpCas9	negative selection	7837248
109694626	109694649	4	+	27260156	NCIH2009	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.23071654464365243	[314]	[598,390,576]	3	hSpCas9	negative selection	7837249
109694586	109694609	4	-	27260156	NCIH2009	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.44607278867351896	[223]	[568,235,504]	6	hSpCas9	negative selection	7901525
109696410	109696433	4	-	27260156	NCIH2009	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.2983176186190952	[449]	[708,576,1022]	4	hSpCas9	negative selection	7901526
109698299	109698322	4	-	27260156	NCIH2009	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.2131012770418339	[659]	[1311,1010,930]	3	hSpCas9	negative selection	7901527
109697621	109697644	4	-	27260156	NCIH1373	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.029965935308746805	[295]	[228,264,174,168]	0	hSpCas9	negative selection	7958498
109697630	109697653	4	+	27260156	NCIH1373	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.5170172684829779	[996]	[752,838,887,161]	-5	hSpCas9	negative selection	7958499
109694626	109694649	4	+	27260156	NCIH1373	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.9826127422697652	[314]	[1490,614,587,51]	8	hSpCas9	negative selection	7958500
109694586	109694609	4	-	27260156	NCIH1373	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.7758347284069305	[223]	[503,320,459,119]	7	hSpCas9	negative selection	8022776
109696410	109696433	4	-	27260156	NCIH1373	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.20538585110775576	[449]	[527,617,396,205]	2	hSpCas9	negative selection	8022777
109698299	109698322	4	-	27260156	NCIH1373	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.5840386187074585	[659]	[1124,1040,912,362]	6	hSpCas9	negative selection	8022778
109697621	109697644	4	-	27260156	PATU8902	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.22336181411126066	[295]	[415,256,156,666]	-2	hSpCas9	negative selection	8079749
109697630	109697653	4	+	27260156	PATU8902	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.47418476040059787	[996]	[856,1200,690,1367]	-5	hSpCas9	negative selection	8079750
109694626	109694649	4	+	27260156	PATU8902	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.11788472218815055	[314]	[627,394,400,495]	1	hSpCas9	negative selection	8079751
109694586	109694609	4	-	27260156	PATU8902	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.8107700295668296	[223]	[440,281,1089,187]	8	hSpCas9	negative selection	8144027
109696410	109696433	4	-	27260156	PATU8902	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	-0.05881487622176877	[449]	[617,631,338,918]	0	hSpCas9	negative selection	8144028
109698299	109698322	4	-	27260156	PATU8902	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.5594919192079134	[659]	[1548,1596,931,1448]	6	hSpCas9	negative selection	8144029
109697621	109697644	4	-	27260156	PANC1	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.011597990471344244	[295]	[123,335,265,291]	0	hSpCas9	negative selection	8201000
109697630	109697653	4	+	27260156	PANC1	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.1851459273955086	[996]	[730,746,1128,446]	-3	hSpCas9	negative selection	8201001
109694626	109694649	4	+	27260156	PANC1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.14058945700090958	[314]	[277,433,366,160]	2	hSpCas9	negative selection	8201002
109694586	109694609	4	-	27260156	PANC1	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.18070632886556115	[223]	[222,174,224,233]	3	hSpCas9	negative selection	8265278
109696410	109696433	4	-	27260156	PANC1	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.12436471992925564	[449]	[437,566,527,210]	2	hSpCas9	negative selection	8265279
109698299	109698322	4	-	27260156	PANC1	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.33096847158395093	[659]	[829,589,744,656]	5	hSpCas9	negative selection	8265280
109697621	109697644	4	-	27260156	PANC0813	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.15926650340853665	[295]	[408,481,329,335]	2	hSpCas9	negative selection	8322251
109697630	109697653	4	+	27260156	PANC0813	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.2889438339375565	[996]	[955,1295,781,805]	-4	hSpCas9	negative selection	8322252
109694626	109694649	4	+	27260156	PANC0813	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.18899696917932496	[314]	[528,375,468,327]	3	hSpCas9	negative selection	8322253
109694586	109694609	4	-	27260156	PANC0813	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.011183370628902845	[223]	[410,241,288,138]	0	hSpCas9	negative selection	8386529
109696410	109696433	4	-	27260156	PANC0813	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	-0.014552312055733305	[449]	[667,416,452,564]	0	hSpCas9	negative selection	8386530
109698299	109698322	4	-	27260156	PANC0813	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.24807754771566504	[659]	[927,747,932,1064]	4	hSpCas9	negative selection	8386531
109697621	109697644	4	-	27260156	RDES	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.14500944505942137	[295]	[219,229,380,441]	-2	hSpCas9	negative selection	8443502
109697630	109697653	4	+	27260156	RDES	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.279462383524286	[996]	[686,947,1162,1029]	-5	hSpCas9	negative selection	8443503
109694626	109694649	4	+	27260156	RDES	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.13021347356620427	[314]	[309,331,313,365]	-2	hSpCas9	negative selection	8443504
109694586	109694609	4	-	27260156	RDES	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.5847945964070312	[223]	[254,337,473,525]	8	hSpCas9	negative selection	8507780
109696410	109696433	4	-	27260156	RDES	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.06495032888395372	[449]	[358,550,456,868]	1	hSpCas9	negative selection	8507781
109698299	109698322	4	-	27260156	RDES	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.4357046180645976	[659]	[841,811,1279,1245]	7	hSpCas9	negative selection	8507782
109697621	109697644	4	-	27260156	PC3	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.35272949346006843	[295]	[121,178,432,303]	-7	hSpCas9	negative selection	8564753
109697630	109697653	4	+	27260156	PC3	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.16500817831760362	[996]	[604,907,1367,879]	-4	hSpCas9	negative selection	8564754
109694626	109694649	4	+	27260156	PC3	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.16088234954404435	[314]	[188,208,555,292]	-4	hSpCas9	negative selection	8564755
109694586	109694609	4	-	27260156	PC3	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.29566995099625437	[223]	[125,144,419,134]	-6	hSpCas9	negative selection	8629031
109696410	109696433	4	-	27260156	PC3	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.24423813030520214	[449]	[379,363,699,775]	5	hSpCas9	negative selection	8629032
109698299	109698322	4	-	27260156	PC3	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	-0.2954056625362588	[659]	[457,522,734,467]	-6	hSpCas9	negative selection	8629033
109697621	109697644	4	-	27260156	PATU8988T	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.15011242693424198	[295]	[433,276,207,101]	-3	hSpCas9	negative selection	8686004
109697630	109697653	4	+	27260156	PATU8988T	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.11320056548603841	[996]	[798,930,960,872]	-2	hSpCas9	negative selection	8686005
109694626	109694649	4	+	27260156	PATU8988T	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.40252314085864005	[314]	[346,514,350,407]	6	hSpCas9	negative selection	8686006
109694586	109694609	4	-	27260156	PATU8988T	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.11662441787722566	[223]	[202,364,139,244]	2	hSpCas9	negative selection	8750282
109696410	109696433	4	-	27260156	PATU8988T	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.20652738885340594	[449]	[480,624,379,536]	3	hSpCas9	negative selection	8750283
109698299	109698322	4	-	27260156	PATU8988T	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.33462944049501653	[659]	[564,1059,729,893]	6	hSpCas9	negative selection	8750284
109697621	109697644	4	-	27260156	T47D	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.3036937182782149	[295]	[214,264,360,275]	-6	hSpCas9	negative selection	8807255
109697630	109697653	4	+	27260156	T47D	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.09858332670859737	[996]	[969,896,1309,1176]	-2	hSpCas9	negative selection	8807256
109694626	109694649	4	+	27260156	T47D	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.33608951476838733	[314]	[452,401,495,507]	7	hSpCas9	negative selection	8807257
109694586	109694609	4	-	27260156	T47D	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.004376547306959244	[223]	[213,245,265,323]	0	hSpCas9	negative selection	8871533
109696410	109696433	4	-	27260156	T47D	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.3487580050301443	[449]	[774,613,620,665]	7	hSpCas9	negative selection	8871534
109698299	109698322	4	-	27260156	T47D	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.28675735178083184	[659]	[1097,746,946,977]	6	hSpCas9	negative selection	8871535
109697621	109697644	4	-	27260156	SU8686	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.02472299537549727	[295]	[311,199,359,290]	0	hSpCas9	negative selection	8928506
109697630	109697653	4	+	27260156	SU8686	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.3178906614844501	[996]	[749,651,844,972]	-5	hSpCas9	negative selection	8928507
109694626	109694649	4	+	27260156	SU8686	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.41657482980088334	[314]	[424,385,439,416]	7	hSpCas9	negative selection	8928508
109694586	109694609	4	-	27260156	SU8686	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	-0.14102603764779853	[223]	[225,164,209,205]	-2	hSpCas9	negative selection	8992784
109696410	109696433	4	-	27260156	SU8686	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.14229549670524577	[449]	[325,445,519,739]	2	hSpCas9	negative selection	8992785
109698299	109698322	4	-	27260156	SU8686	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.23708760271546392	[659]	[712,799,802,765]	4	hSpCas9	negative selection	8992786
109697621	109697644	4	-	27260156	SKES1	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.17139817340413266	[295]	[276,295,282,202]	-4	hSpCas9	negative selection	9049757
109697630	109697653	4	+	27260156	SKES1	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.15439588366582757	[996]	[1222,1006,729,690]	-3	hSpCas9	negative selection	9049758
109694626	109694649	4	+	27260156	SKES1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.27121070365754246	[314]	[487,492,264,305]	6	hSpCas9	negative selection	9049759
109694586	109694609	4	-	27260156	SKES1	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.2511246265340662	[223]	[369,267,340,113]	5	hSpCas9	negative selection	9114035
109696410	109696433	4	-	27260156	SKES1	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.27985470560288644	[449]	[629,591,465,508]	6	hSpCas9	negative selection	9114036
109698299	109698322	4	-	27260156	SKES1	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.10106121581191618	[659]	[601,835,802,589]	2	hSpCas9	negative selection	9114037
109697621	109697644	4	-	27260156	TOV112D	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.4088269511565361	[295]	[139,280,145,329]	-7	hSpCas9	negative selection	9171008
109697630	109697653	4	+	27260156	TOV112D	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.29721910259442463	[996]	[845,1058,716,693]	-5	hSpCas9	negative selection	9171009
109694626	109694649	4	+	27260156	TOV112D	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.2766915169109433	[314]	[463,413,324,340]	5	hSpCas9	negative selection	9171010
109694586	109694609	4	-	27260156	TOV112D	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.5928486986440554	[223]	[307,204,410,391]	9	hSpCas9	negative selection	9235286
109696410	109696433	4	-	27260156	TOV112D	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.33121057016209554	[449]	[416,945,499,486]	6	hSpCas9	negative selection	9235287
109698299	109698322	4	-	27260156	TOV112D	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.22685802205937633	[659]	[530,656,830,1017]	4	hSpCas9	negative selection	9235288
109697621	109697644	4	-	27260156	TC71	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.186633167915781	[295]	[303,184,308,317]	-5	hSpCas9	negative selection	9292259
109697630	109697653	4	+	27260156	TC71	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.08765362851443514	[996]	[1067,947,995,1009]	-2	hSpCas9	negative selection	9292260
109694626	109694649	4	+	27260156	TC71	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.44679907830907045	[314]	[486,429,484,435]	8	hSpCas9	negative selection	9292261
109694586	109694609	4	-	27260156	TC71	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.039262121495867275	[223]	[240,234,228,284]	1	hSpCas9	negative selection	9356537
109696410	109696433	4	-	27260156	TC71	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.21729102065840072	[449]	[479,502,670,588]	5	hSpCas9	negative selection	9356538
109698299	109698322	4	-	27260156	TC71	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.05284928625462271	[659]	[678,724,762,770]	1	hSpCas9	negative selection	9356539
109697621	109697644	4	-	27260156	TC32	viability	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	-0.01467896933226942	[295]	[274,214,304,319]	0	hSpCas9	negative selection	9413510
109697630	109697653	4	+	27260156	TC32	viability	AAGATTGTCTCTATCTGCGCAGG	CASP6	ENSG00000138794	-0.15667133929060506	[996]	[592,799,1330,710]	-3	hSpCas9	negative selection	9413511
109694626	109694649	4	+	27260156	TC32	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.4531894157259669	[314]	[463,289,443,442]	7	hSpCas9	negative selection	9413512
109694586	109694609	4	-	27260156	TC32	viability	ATCGAAATTCAGACATTAACTGG	CASP6	ENSG00000138794	0.42986323990162134	[223]	[241,253,313,330]	7	hSpCas9	negative selection	9477788
109696410	109696433	4	-	27260156	TC32	viability	ACTACTGCTCAAAATTCATGAGG	CASP6	ENSG00000138794	0.017592850790090396	[449]	[386,341,584,437]	0	hSpCas9	negative selection	9477789
109698299	109698322	4	-	27260156	TC32	viability	AAACAGATGCCTTCTATAAAAGG	CASP6	ENSG00000138794	0.3230542772297075	[659]	[700,678,973,781]	5	hSpCas9	negative selection	9477790
109689450	109689473	4	-	27869803	HPAFII	viability after 27 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	1.238733377907776	[280]	[370,329,NaN]	8	hSpCas9	negative selection	9586603
109689468	109689491	4	+	27869803	HPAFII	viability after 27 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.6603983838521728	[56]	[36,55,NaN]	5	hSpCas9	negative selection	9586604
109690887	109690910	4	+	27869803	HPAFII	viability after 27 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.1564191773991609	[486]	[286,181,NaN]	-1	hSpCas9	negative selection	9586605
109694626	109694649	4	+	27869803	HPAFII	viability after 27 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.9421696296756974	[160]	[190,138,NaN]	7	hSpCas9	negative selection	9586606
109697621	109697644	4	-	27869803	HPAFII	viability after 27 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.795977532065453	[121]	[112,109,NaN]	6	hSpCas9	negative selection	9586607
109697660	109697683	4	-	27869803	HPAFII	viability after 27 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	1.7011623728314267	[86]	[121,170,NaN]	9	hSpCas9	negative selection	9586608
109689450	109689473	4	-	27869803	HPAFII	viability after 15 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.9531469458476537	[280]	[736,489,NaN]	9	hSpCas9	negative selection	9669052
109689468	109689491	4	+	27869803	HPAFII	viability after 15 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.7183408585479547	[56]	[167,58,NaN]	7	hSpCas9	negative selection	9669053
109690887	109690910	4	+	27869803	HPAFII	viability after 15 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.017211120159390192	[486]	[615,475,NaN]	0	hSpCas9	negative selection	9669054
109694626	109694649	4	+	27869803	HPAFII	viability after 15 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.5524582305932081	[160]	[410,155,NaN]	6	hSpCas9	negative selection	9669055
109697621	109697644	4	-	27869803	HPAFII	viability after 15 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.23447289303669971	[121]	[218,113,NaN]	2	hSpCas9	negative selection	9669056
109697660	109697683	4	-	27869803	HPAFII	viability after 15 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.900121624775013	[86]	[118,208,NaN]	8	hSpCas9	negative selection	9669057
109689450	109689473	4	-	27869803	ASPC1	viability after 36 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.41073081005898104	[729]	[551,307,209]	4	hSpCas9	negative selection	9751501
109689468	109689491	4	+	27869803	ASPC1	viability after 36 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.8994483770062047	[123]	[22,113,93]	8	hSpCas9	negative selection	9751502
109690887	109690910	4	+	27869803	ASPC1	viability after 36 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.8184187536462942	[1050]	[866,744,407]	7	hSpCas9	negative selection	9751503
109694626	109694649	4	+	27869803	ASPC1	viability after 36 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.7250139349537781	[504]	[154,85,87]	-6	hSpCas9	negative selection	9751504
109697621	109697644	4	-	27869803	ASPC1	viability after 36 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.1477201789728299	[400]	[315,122,65]	1	hSpCas9	negative selection	9751505
109697660	109697683	4	-	27869803	ASPC1	viability after 36 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	-1.6053973053268464	[367]	[51,60,19]	-8	hSpCas9	negative selection	9751506
109689450	109689473	4	-	27869803	PATU8988S	viability after 35 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.5607843000686924	[594]	[344,361,NaN]	6	hSpCas9	negative selection	9833950
109689468	109689491	4	+	27869803	PATU8988S	viability after 35 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.5619102969066434	[142]	[93,75,NaN]	6	hSpCas9	negative selection	9833951
109690887	109690910	4	+	27869803	PATU8988S	viability after 35 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.41240996031084176	[1066]	[273,371,NaN]	-4	hSpCas9	negative selection	9833952
109694626	109694649	4	+	27869803	PATU8988S	viability after 35 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.43975732496227654	[393]	[98,331,NaN]	5	hSpCas9	negative selection	9833953
109697621	109697644	4	-	27869803	PATU8988S	viability after 35 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.822609444045167	[274]	[144,246,NaN]	8	hSpCas9	negative selection	9833954
109697660	109697683	4	-	27869803	PATU8988S	viability after 35 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	0.3911544437611302	[211]	[100,122,NaN]	4	hSpCas9	negative selection	9833955
109689450	109689473	4	-	27869803	PATU8988S	viability after 31 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	0.5887133094418009	[594]	[186,572,NaN]	7	hSpCas9	negative selection	9916399
109689468	109689491	4	+	27869803	PATU8988S	viability after 31 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.10017277488613496	[142]	[61,59,NaN]	1	hSpCas9	negative selection	9916400
109690887	109690910	4	+	27869803	PATU8988S	viability after 31 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.054690358080456525	[1066]	[373,454,NaN]	0	hSpCas9	negative selection	9916401
109694626	109694649	4	+	27869803	PATU8988S	viability after 31 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.19581403324193475	[393]	[98,282,NaN]	2	hSpCas9	negative selection	9916402
109697621	109697644	4	-	27869803	PATU8988S	viability after 31 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.929661696712546	[274]	[174,251,NaN]	9	hSpCas9	negative selection	9916403
109697660	109697683	4	-	27869803	PATU8988S	viability after 31 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	-0.06950046952693589	[211]	[69,93,NaN]	-1	hSpCas9	negative selection	9916404
109689450	109689473	4	-	27869803	HPAFII	viability after 35 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	1.765877329942902	[280]	[519,442,NaN]	9	hSpCas9	negative selection	9998848
109689468	109689491	4	+	27869803	HPAFII	viability after 35 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	0.9538014895789828	[56]	[77,30,NaN]	6	hSpCas9	negative selection	9998849
109690887	109690910	4	+	27869803	HPAFII	viability after 35 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.21285501942915774	[486]	[247,172,NaN]	-1	hSpCas9	negative selection	9998850
109694626	109694649	4	+	27869803	HPAFII	viability after 35 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.4813079278730799	[160]	[299,145,NaN]	8	hSpCas9	negative selection	9998851
109697621	109697644	4	-	27869803	HPAFII	viability after 35 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	1.4855179072461748	[121]	[179,164,NaN]	8	hSpCas9	negative selection	9998852
109697660	109697683	4	-	27869803	HPAFII	viability after 35 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	1.4932493911846019	[86]	[107,141,NaN]	8	hSpCas9	negative selection	9998853
109689450	109689473	4	-	27869803	HPAFII	viability after 31 days	AACTCCTCACACTGGTGAACAGG	CASP6	ENSG00000138794	1.5747819767068765	[280]	[408,535,NaN]	9	hSpCas9	negative selection	10081297
109689468	109689491	4	+	27869803	HPAFII	viability after 31 days	GAGTTCTGTGAACTCTAAGGAGG	CASP6	ENSG00000138794	1.1013687520613895	[56]	[93,40,NaN]	7	hSpCas9	negative selection	10081298
109690887	109690910	4	+	27869803	HPAFII	viability after 31 days	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	-0.006943921156744914	[486]	[271,271,NaN]	0	hSpCas9	negative selection	10081299
109694626	109694649	4	+	27869803	HPAFII	viability after 31 days	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.4167967382046474	[160]	[335,137,NaN]	9	hSpCas9	negative selection	10081300
109697621	109697644	4	-	27869803	HPAFII	viability after 31 days	ATAGAGACAATCTTACCCGCAGG	CASP6	ENSG00000138794	0.6930521818922598	[121]	[114,105,NaN]	5	hSpCas9	negative selection	10081301
109697660	109697683	4	-	27869803	HPAFII	viability after 31 days	GGCACTTAACACTGCCAGAAAGG	CASP6	ENSG00000138794	1.8317712666213817	[86]	[135,214,NaN]	9	hSpCas9	negative selection	10081302
109694643	109694666	4	-	28162770	P31FUJ	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.05086353419154588	[404]	[492]	0	hSpCas9	negative selection	10126225
109690999	109691022	4	-	28162770	P31FUJ	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.5116385103139741	[230]	[386]	6	hSpCas9	negative selection	10126226
109690973	109690996	4	+	28162770	P31FUJ	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.6982504418681298	[224]	[428]	7	hSpCas9	negative selection	10126227
109690887	109690910	4	+	28162770	P31FUJ	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.5402828155584795	[212]	[363]	6	hSpCas9	negative selection	10126228
109694626	109694649	4	+	28162770	P31FUJ	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.1045559310425899	[92]	[234]	9	hSpCas9	negative selection	10126229
109690919	109690942	4	-	28162770	P31FUJ	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.41955116203688614	[473]	[744]	5	hSpCas9	negative selection	10126230
109694550	109694573	4	-	28162770	P31FUJ	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.5620833656810089	[165]	[287]	6	hSpCas9	negative selection	10126231
109703386	109703409	4	-	28162770	P31FUJ	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.26799984864277904	[799]	[1131]	3	hSpCas9	negative selection	10126232
109690853	109690876	4	+	28162770	P31FUJ	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.5884919086010992	[411]	[727]	6	hSpCas9	negative selection	10126233
109694665	109694688	4	+	28162770	P31FUJ	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	1.0282969965137014	[372]	[893]	9	hSpCas9	negative selection	10126234
109694643	109694666	4	-	28162770	TF1	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	NaN	[NaN]	[285]	1	hSpCas9	negative selection	10295591
109690999	109691022	4	-	28162770	TF1	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10295592
109690973	109690996	4	+	28162770	TF1	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	NaN	[NaN]	[271]	1	hSpCas9	negative selection	10295593
109690887	109690910	4	+	28162770	TF1	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10295594
109694626	109694649	4	+	28162770	TF1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10295595
109690919	109690942	4	-	28162770	TF1	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	NaN	[NaN]	[285]	1	hSpCas9	negative selection	10295596
109694550	109694573	4	-	28162770	TF1	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10295597
109703386	109703409	4	-	28162770	TF1	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	NaN	[NaN]	[970]	1	hSpCas9	negative selection	10295598
109690853	109690876	4	+	28162770	TF1	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	NaN	[NaN]	[601]	1	hSpCas9	negative selection	10295599
109694665	109694688	4	+	28162770	TF1	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	NaN	[NaN]	[500]	1	hSpCas9	negative selection	10295600
109694643	109694666	4	-	28162770	SKM1	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.18333174628103532	[134]	[270]	1	hSpCas9	negative selection	10464957
109690999	109691022	4	-	28162770	SKM1	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.22332229248748475	[46]	[96]	2	hSpCas9	negative selection	10464958
109690973	109690996	4	+	28162770	SKM1	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.9616046212629896	[69]	[240]	8	hSpCas9	negative selection	10464959
109690887	109690910	4	+	28162770	SKM1	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.6947893000575713	[64]	[185]	6	hSpCas9	negative selection	10464960
109694626	109694649	4	+	28162770	SKM1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.5150332892555651	[37]	[95]	5	hSpCas9	negative selection	10464961
109690919	109690942	4	-	28162770	SKM1	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.255534902449015	[162]	[343]	2	hSpCas9	negative selection	10464962
109694550	109694573	4	-	28162770	SKM1	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.8725852938736488	[37]	[122]	8	hSpCas9	negative selection	10464963
109703386	109703409	4	-	28162770	SKM1	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.3734236757141731	[161]	[370]	3	hSpCas9	negative selection	10464964
109690853	109690876	4	+	28162770	SKM1	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.8616947562845103	[79]	[256]	7	hSpCas9	negative selection	10464965
109694665	109694688	4	+	28162770	SKM1	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.965268977992266	[92]	[320]	8	hSpCas9	negative selection	10464966
109694643	109694666	4	-	28162770	SKM1	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.18333174628103532	[134]	[270]	1	hSpCas9	negative selection	10634323
109690999	109691022	4	-	28162770	SKM1	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.22332229248748475	[46]	[96]	2	hSpCas9	negative selection	10634324
109690973	109690996	4	+	28162770	SKM1	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.9616046212629896	[69]	[240]	8	hSpCas9	negative selection	10634325
109690887	109690910	4	+	28162770	SKM1	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.6947893000575713	[64]	[185]	6	hSpCas9	negative selection	10634326
109694626	109694649	4	+	28162770	SKM1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.5150332892555651	[37]	[95]	5	hSpCas9	negative selection	10634327
109690919	109690942	4	-	28162770	SKM1	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.255534902449015	[162]	[343]	2	hSpCas9	negative selection	10634328
109694550	109694573	4	-	28162770	SKM1	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.8725852938736488	[37]	[122]	8	hSpCas9	negative selection	10634329
109703386	109703409	4	-	28162770	SKM1	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.3734236757141731	[161]	[370]	3	hSpCas9	negative selection	10634330
109690853	109690876	4	+	28162770	SKM1	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.8616947562845103	[79]	[256]	7	hSpCas9	negative selection	10634331
109694665	109694688	4	+	28162770	SKM1	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.965268977992266	[92]	[320]	8	hSpCas9	negative selection	10634332
109694643	109694666	4	-	28162770	PL21	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.4350960927130597	[437]	[140]	-3	hSpCas9	negative selection	10803689
109690999	109691022	4	-	28162770	PL21	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	1.0860678477805252	[170]	[157]	8	hSpCas9	negative selection	10803690
109690973	109690996	4	+	28162770	PL21	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	-0.3507610501582031	[292]	[99]	-3	hSpCas9	negative selection	10803691
109690887	109690910	4	+	28162770	PL21	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.16771813679694275	[224]	[109]	1	hSpCas9	negative selection	10803692
109694626	109694649	4	+	28162770	PL21	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.49102229006376125	[154]	[47]	-4	hSpCas9	negative selection	10803693
109690919	109690942	4	-	28162770	PL21	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.15766269812515743	[516]	[250]	1	hSpCas9	negative selection	10803694
109694550	109694573	4	-	28162770	PL21	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.5263678468103079	[133]	[83]	4	hSpCas9	negative selection	10803695
109703386	109703409	4	-	28162770	PL21	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.4762640197635577	[511]	[309]	4	hSpCas9	negative selection	10803696
109690853	109690876	4	+	28162770	PL21	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	-0.5664296927217839	[278]	[81]	-4	hSpCas9	negative selection	10803697
109694665	109694688	4	+	28162770	PL21	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	1.188955875996644	[258]	[256]	8	hSpCas9	negative selection	10803698
109694643	109694666	4	-	28162770	P31FUJ	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.05086353419154588	[404]	[492]	0	hSpCas9	negative selection	10973055
109690999	109691022	4	-	28162770	P31FUJ	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.5116385103139741	[230]	[386]	6	hSpCas9	negative selection	10973056
109690973	109690996	4	+	28162770	P31FUJ	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.6982504418681298	[224]	[428]	7	hSpCas9	negative selection	10973057
109690887	109690910	4	+	28162770	P31FUJ	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.5402828155584795	[212]	[363]	6	hSpCas9	negative selection	10973058
109694626	109694649	4	+	28162770	P31FUJ	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.1045559310425899	[92]	[234]	9	hSpCas9	negative selection	10973059
109690919	109690942	4	-	28162770	P31FUJ	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.41955116203688614	[473]	[744]	5	hSpCas9	negative selection	10973060
109694550	109694573	4	-	28162770	P31FUJ	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.5620833656810089	[165]	[287]	6	hSpCas9	negative selection	10973061
109703386	109703409	4	-	28162770	P31FUJ	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.26799984864277904	[799]	[1131]	3	hSpCas9	negative selection	10973062
109690853	109690876	4	+	28162770	P31FUJ	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.5884919086010992	[411]	[727]	6	hSpCas9	negative selection	10973063
109694665	109694688	4	+	28162770	P31FUJ	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	1.0282969965137014	[372]	[893]	9	hSpCas9	negative selection	10973064
109694643	109694666	4	-	28162770	OCIAML5	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.13001152113874065	[161]	[319]	1	hSpCas9	negative selection	11142421
109690999	109691022	4	-	28162770	OCIAML5	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	-0.054979984260219966	[140]	[244]	0	hSpCas9	negative selection	11142422
109690973	109690996	4	+	28162770	OCIAML5	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	1.3772369776572473	[118]	[557]	9	hSpCas9	negative selection	11142423
109690887	109690910	4	+	28162770	OCIAML5	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.7536544900239567	[114]	[349]	6	hSpCas9	negative selection	11142424
109694626	109694649	4	+	28162770	OCIAML5	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.8872240762484529	[61]	[206]	7	hSpCas9	negative selection	11142425
109690919	109690942	4	-	28162770	OCIAML5	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.7745888781571195	[215]	[666]	6	hSpCas9	negative selection	11142426
109694550	109694573	4	-	28162770	OCIAML5	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.8303617392927766	[61]	[198]	7	hSpCas9	negative selection	11142427
109703386	109703409	4	-	28162770	OCIAML5	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.25855260181593365	[388]	[839]	2	hSpCas9	negative selection	11142428
109690853	109690876	4	+	28162770	OCIAML5	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.5895317546859816	[221]	[602]	5	hSpCas9	negative selection	11142429
109694665	109694688	4	+	28162770	OCIAML5	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.6692798305611877	[169]	[487]	6	hSpCas9	negative selection	11142430
109694643	109694666	4	-	28162770	EOL1	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.03452196437458355	[833]	[428]	0	hSpCas9	negative selection	11311787
109690999	109691022	4	-	28162770	EOL1	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.36778216268003044	[227]	[154]	3	hSpCas9	negative selection	11311788
109690973	109690996	4	+	28162770	EOL1	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.28776407494852896	[495]	[318]	2	hSpCas9	negative selection	11311789
109690887	109690910	4	+	28162770	EOL1	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.9903724075301259	[406]	[425]	8	hSpCas9	negative selection	11311790
109694626	109694649	4	+	28162770	EOL1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.7217308885708473	[243]	[423]	9	hSpCas9	negative selection	11311791
109690919	109690942	4	-	28162770	EOL1	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.28711785095524256	[937]	[602]	2	hSpCas9	negative selection	11311792
109694550	109694573	4	-	28162770	EOL1	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	1.7408358183981465	[137]	[242]	9	hSpCas9	negative selection	11311793
109703386	109703409	4	-	28162770	EOL1	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.6757506033935134	[725]	[610]	6	hSpCas9	negative selection	11311794
109690853	109690876	4	+	28162770	EOL1	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	-0.7442463199540924	[371]	[116]	-5	hSpCas9	negative selection	11311795
109694665	109694688	4	+	28162770	EOL1	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.6637142739300119	[392]	[327]	6	hSpCas9	negative selection	11311796
109694643	109694666	4	-	28162770	MOLM13	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.28955214028606624	[515]	[455]	2	hSpCas9	negative selection	11481153
109690999	109691022	4	-	28162770	MOLM13	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.09865557187885965	[216]	[167]	0	hSpCas9	negative selection	11481154
109690973	109690996	4	+	28162770	MOLM13	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	1.393711793163473	[428]	[814]	9	hSpCas9	negative selection	11481155
109690887	109690910	4	+	28162770	MOLM13	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.866003577786954	[342]	[451]	6	hSpCas9	negative selection	11481156
109694626	109694649	4	+	28162770	MOLM13	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.2827779762875906	[190]	[335]	8	hSpCas9	negative selection	11481157
109690919	109690942	4	-	28162770	MOLM13	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.7230995709318606	[831]	[992]	5	hSpCas9	negative selection	11481158
109694550	109694573	4	-	28162770	MOLM13	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.0802851123888475	[190]	[145]	0	hSpCas9	negative selection	11481159
109703386	109703409	4	-	28162770	MOLM13	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.49494567997483685	[897]	[914]	3	hSpCas9	negative selection	11481160
109690853	109690876	4	+	28162770	MOLM13	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	-0.10895438620967379	[442]	[296]	0	hSpCas9	negative selection	11481161
109694665	109694688	4	+	28162770	MOLM13	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	1.0224782332222162	[351]	[516]	7	hSpCas9	negative selection	11481162
109694643	109694666	4	-	28162770	HEL	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.6572093148086904	[495]	[500]	5	hSpCas9	negative selection	11650519
109690999	109691022	4	-	28162770	HEL	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	-0.015287130910522752	[242]	[153]	0	hSpCas9	negative selection	11650520
109690973	109690996	4	+	28162770	HEL	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	1.4739511542597432	[316]	[563]	9	hSpCas9	negative selection	11650521
109690887	109690910	4	+	28162770	HEL	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.025765936376579923	[318]	[207]	0	hSpCas9	negative selection	11650522
109694626	109694649	4	+	28162770	HEL	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.6036390123114165	[186]	[181]	5	hSpCas9	negative selection	11650523
109690919	109690942	4	-	28162770	HEL	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.402133607405879	[650]	[550]	3	hSpCas9	negative selection	11650524
109694550	109694573	4	-	28162770	HEL	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	-0.33062604149617636	[160]	[81]	-2	hSpCas9	negative selection	11650525
109703386	109703409	4	-	28162770	HEL	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.35817126461692195	[647]	[531]	3	hSpCas9	negative selection	11650526
109690853	109690876	4	+	28162770	HEL	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.11549182913548794	[342]	[237]	0	hSpCas9	negative selection	11650527
109694665	109694688	4	+	28162770	HEL	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.37331879115325206	[316]	[262]	3	hSpCas9	negative selection	11650528
109694643	109694666	4	-	28162770	MV411	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.012387298575128325	[448]	[374]	0	hSpCas9	negative selection	11819885
109690999	109691022	4	-	28162770	MV411	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	-1.8934249850570744	[171]	[38]	-8	hSpCas9	negative selection	11819886
109690973	109690996	4	+	28162770	MV411	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.7315166944912704	[305]	[427]	6	hSpCas9	negative selection	11819887
109690887	109690910	4	+	28162770	MV411	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.7876617367386469	[261]	[380]	7	hSpCas9	negative selection	11819888
109694626	109694649	4	+	28162770	MV411	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.067616513197963	[127]	[225]	8	hSpCas9	negative selection	11819889
109690919	109690942	4	-	28162770	MV411	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	-0.046553667601463955	[536]	[437]	0	hSpCas9	negative selection	11819890
109694550	109694573	4	-	28162770	MV411	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.9478772689238674	[95]	[155]	8	hSpCas9	negative selection	11819891
109703386	109703409	4	-	28162770	MV411	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.7566047009617272	[507]	[722]	6	hSpCas9	negative selection	11819892
109690853	109690876	4	+	28162770	MV411	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	-0.11666567969296604	[268]	[208]	-1	hSpCas9	negative selection	11819893
109694665	109694688	4	+	28162770	MV411	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	1.2355143834069562	[242]	[481]	9	hSpCas9	negative selection	11819894
109694643	109694666	4	-	28162770	MONOMAC1	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.41664447078312916	[314]	[481]	4	hSpCas9	negative selection	11989251
109690999	109691022	4	-	28162770	MONOMAC1	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.07332089958009916	[130]	[157]	0	hSpCas9	negative selection	11989252
109690973	109690996	4	+	28162770	MONOMAC1	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.030373649043518858	[163]	[191]	0	hSpCas9	negative selection	11989253
109690887	109690910	4	+	28162770	MONOMAC1	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.4578276668917589	[140]	[221]	4	hSpCas9	negative selection	11989254
109694626	109694649	4	+	28162770	MONOMAC1	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	0.6748068014497641	[99]	[182]	6	hSpCas9	negative selection	11989255
109690919	109690942	4	-	28162770	MONOMAC1	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	-0.08631002919302255	[350]	[378]	0	hSpCas9	negative selection	11989256
109694550	109694573	4	-	28162770	MONOMAC1	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	1.0329687583867693	[80]	[189]	8	hSpCas9	negative selection	11989257
109703386	109703409	4	-	28162770	MONOMAC1	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.7756026895484536	[345]	[678]	7	hSpCas9	negative selection	11989258
109690853	109690876	4	+	28162770	MONOMAC1	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	-0.13181918761307299	[172]	[180]	-1	hSpCas9	negative selection	11989259
109694665	109694688	4	+	28162770	MONOMAC1	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.15867956128409222	[210]	[269]	1	hSpCas9	negative selection	11989260
109694643	109694666	4	-	28162770	OCIAML2	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	0.3889550555880009	[61]	[449]	4	hSpCas9	negative selection	12158617
109690999	109691022	4	-	28162770	OCIAML2	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	0.45929173902169806	[28]	[220]	4	hSpCas9	negative selection	12158618
109690973	109690996	4	+	28162770	OCIAML2	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.2108406563323414	[52]	[339]	2	hSpCas9	negative selection	12158619
109690887	109690910	4	+	28162770	OCIAML2	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.7875223592118864	[36]	[353]	7	hSpCas9	negative selection	12158620
109694626	109694649	4	+	28162770	OCIAML2	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	1.1732263645325633	[13]	[174]	9	hSpCas9	negative selection	12158621
109690919	109690942	4	-	28162770	OCIAML2	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	0.05791936657372854	[112]	[651]	0	hSpCas9	negative selection	12158622
109694550	109694573	4	-	28162770	OCIAML2	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	0.9037656895393367	[26]	[279]	8	hSpCas9	negative selection	12158623
109703386	109703409	4	-	28162770	OCIAML2	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	0.27287861479081665	[98]	[662]	2	hSpCas9	negative selection	12158624
109690853	109690876	4	+	28162770	OCIAML2	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	0.6134344395463132	[49]	[423]	6	hSpCas9	negative selection	12158625
109694665	109694688	4	+	28162770	OCIAML2	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	0.8512982696452012	[46]	[469]	8	hSpCas9	negative selection	12158626
109694643	109694666	4	-	28162770	OCIAML3	viability	GTGTGTGTCTTCCTGAGCCATGG	CASP6	ENSG00000138794	-0.2231699449558544	[144]	[374]	-2	hSpCas9	negative selection	12327983
109690999	109691022	4	-	28162770	OCIAML3	viability	CTTGTCTTGTAGGCATGTCGGGG	CASP6	ENSG00000138794	1.0454026444193694	[51]	[323]	8	hSpCas9	negative selection	12327984
109690973	109690996	4	+	28162770	OCIAML3	viability	GAATGACTGGCACATCGTGCTGG	CASP6	ENSG00000138794	0.3624907210392504	[100]	[391]	3	hSpCas9	negative selection	12327985
109690887	109690910	4	+	28162770	OCIAML3	viability	AGCAGGCAGCGTGTAAACGGAGG	CASP6	ENSG00000138794	0.6076262208454875	[54]	[252]	5	hSpCas9	negative selection	12327986
109694626	109694649	4	+	28162770	OCIAML3	viability	AAATGTGATTGCCTTCGCCATGG	CASP6	ENSG00000138794	-0.09805014566175185	[38]	[109]	-1	hSpCas9	negative selection	12327987
109690919	109690942	4	-	28162770	OCIAML3	viability	GTTGGACACCAACATAACTGAGG	CASP6	ENSG00000138794	-0.4679541373177666	[114]	[250]	-4	hSpCas9	negative selection	12327988
109694550	109694573	4	-	28162770	OCIAML3	viability	GACAAGTGTCACAGCCTGGTTGG	CASP6	ENSG00000138794	-0.7403971273056864	[56]	[102]	-5	hSpCas9	negative selection	12327989
109703386	109703409	4	-	28162770	OCIAML3	viability	GCGTTTGGCTGCAATGAGCTCGG	CASP6	ENSG00000138794	-0.060760176147162115	[141]	[410]	0	hSpCas9	negative selection	12327990
109690853	109690876	4	+	28162770	OCIAML3	viability	CTGCAACAGAGTAACACATGAGG	CASP6	ENSG00000138794	1.5548557455903196	[68]	[611]	9	hSpCas9	negative selection	12327991
109694665	109694688	4	+	28162770	OCIAML3	viability	CAAAGCAATCGGCATCTGCGTGG	CASP6	ENSG00000138794	1.545922620820312	[80]	[713]	9	hSpCas9	negative selection	12327992