Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:841
• Symbol:CASP8
• Description:caspase 8

DataSource: http://genomecrispr.dkfz.de/#!/results/CASP8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
201266665	201266688	2	-	26472758	Jiyoye	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	1.123382415505282	[55]	[91]	7	hSpCas9	negative selection	23799
201272662	201272685	2	+	26472758	Jiyoye	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.9584740908108071	[66]	[25]	-6	hSpCas9	negative selection	23800
201266750	201266773	2	+	26472758	Jiyoye	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	1.2529285939213621	[142]	[256]	7	hSpCas9	negative selection	23801
201276845	201276868	2	+	26472758	Jiyoye	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	0.6213001868587208	[74]	[86]	4	hSpCas9	negative selection	23802
201266545	201266568	2	-	26472758	Jiyoye	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.4230293327067105	[180]	[182]	3	hSpCas9	negative selection	23803
201266563	201266586	2	+	26472758	Jiyoye	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.2706023286304294	[154]	[140]	2	hSpCas9	negative selection	23804
201276860	201276883	2	-	26472758	Jiyoye	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.9521714749093848	[60]	[88]	6	hSpCas9	negative selection	23805
201266582	201266605	2	+	26472758	Jiyoye	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.8874405035603362	[199]	[278]	6	hSpCas9	negative selection	23806
201266608	201266631	2	-	26472758	Jiyoye	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.028663758252143623	[90]	[69]	0	hSpCas9	negative selection	23807
201266717	201266740	2	+	26472758	Jiyoye	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	0.18478296016942553	[20]	[17]	1	hSpCas9	negative selection	23808
201266665	201266688	2	-	26472758	KBM7	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	0.7045517546883291	[321,209]	[267,139]	7	hSpCas9	negative selection	214917
201272662	201272685	2	+	26472758	KBM7	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	1.4439410089228306	[129,174]	[123,265]	9	hSpCas9	negative selection	214918
201266750	201266773	2	+	26472758	KBM7	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	1.1749019566322114	[756,849]	[688,1016]	9	hSpCas9	negative selection	214919
201276845	201276868	2	+	26472758	KBM7	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	0.9024107734189815	[225,209]	[270,120]	8	hSpCas9	negative selection	214920
201266545	201266568	2	-	26472758	KBM7	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	1.6967251585616698	[738,586]	[1048,962]	9	hSpCas9	negative selection	214921
201266563	201266586	2	+	26472758	KBM7	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.7031002845567766	[560,384]	[461,262]	7	hSpCas9	negative selection	214922
201276860	201276883	2	-	26472758	KBM7	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	1.6717889029719448	[184,185]	[244,309]	9	hSpCas9	negative selection	214923
201266582	201266605	2	+	26472758	KBM7	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	1.1689533516679913	[701,805]	[822,791]	9	hSpCas9	negative selection	214924
201266608	201266631	2	-	26472758	KBM7	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	1.3754408920111725	[189,145]	[208,197]	9	hSpCas9	negative selection	214925
201266717	201266740	2	+	26472758	KBM7	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	1.2936112128341075	[82,76]	[95,88]	9	hSpCas9	negative selection	214926
201266665	201266688	2	-	26472758	Raji	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	0.7255129000299548	[85]	[32]	6	hSpCas9	negative selection	406035
201272662	201272685	2	+	26472758	Raji	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	1.8806126735265773	[54]	[46]	9	hSpCas9	negative selection	406036
201266750	201266773	2	+	26472758	Raji	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.8041054975939019	[268]	[108]	7	hSpCas9	negative selection	406037
201276845	201276868	2	+	26472758	Raji	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	0.5668151540108967	[95]	[32]	5	hSpCas9	negative selection	406038
201266545	201266568	2	-	26472758	Raji	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.4983354161281303	[301]	[98]	5	hSpCas9	negative selection	406039
201266563	201266586	2	+	26472758	Raji	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.07318871026822138	[203]	[44]	0	hSpCas9	negative selection	406040
201276860	201276883	2	-	26472758	Raji	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.4867971249217221	[122]	[39]	4	hSpCas9	negative selection	406041
201266582	201266605	2	+	26472758	Raji	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.5048484052044936	[412]	[135]	5	hSpCas9	negative selection	406042
201266608	201266631	2	-	26472758	Raji	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.13692781098761486	[144]	[36]	1	hSpCas9	negative selection	406043
201266717	201266740	2	+	26472758	Raji	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	0.3968901525685844	[35]	[10]	4	hSpCas9	negative selection	406044
201266665	201266688	2	-	26472758	K562	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	-0.22365353393426524	[313]	[226]	-1	hSpCas9	negative selection	597153
201272662	201272685	2	+	26472758	K562	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	0.6856877685184704	[108]	[147]	5	hSpCas9	negative selection	597154
201266750	201266773	2	+	26472758	K562	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.665814523005656	[565]	[757]	5	hSpCas9	negative selection	597155
201276845	201276868	2	+	26472758	K562	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	0.13479423649194888	[204]	[189]	1	hSpCas9	negative selection	597156
201266545	201266568	2	-	26472758	K562	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.6968532156057323	[713]	[976]	6	hSpCas9	negative selection	597157
201266563	201266586	2	+	26472758	K562	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.6120243969484536	[285]	[368]	5	hSpCas9	negative selection	597158
201276860	201276883	2	-	26472758	K562	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.38778290283762407	[133]	[147]	3	hSpCas9	negative selection	597159
201266582	201266605	2	+	26472758	K562	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.8360581760320112	[502]	[757]	7	hSpCas9	negative selection	597160
201266608	201266631	2	-	26472758	K562	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	1.106915203916512	[120]	[219]	8	hSpCas9	negative selection	597161
201266717	201266740	2	+	26472758	K562	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	1.9073837403888763	[23]	[75]	9	hSpCas9	negative selection	597162
201258310	201258333	2	-	26627737	DLD1	viability	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	2.2525670287331536	[93]	[151,141,127]	9	hSpCas9	negative selection	809911
201266563	201266586	2	+	26627737	DLD1	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.348392378019032	[810]	[247,384,335]	3	hSpCas9	negative selection	809912
201269563	201269586	2	+	26627737	DLD1	viability	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.1957761615758778	[733]	[344,128,133]	-2	hSpCas9	negative selection	809913
201274917	201274940	2	+	26627737	DLD1	viability	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	-0.12909837761578546	[1014]	[362,341,183]	-1	hSpCas9	negative selection	809914
201276924	201276947	2	+	26627737	DLD1	viability	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	-0.6107789833529293	[517]	[120,151,54]	-5	hSpCas9	negative selection	809915
201285121	201285144	2	-	26627737	DLD1	viability	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.07290218823572686	[338]	[124,97,81]	-1	hSpCas9	negative selection	809916
201258310	201258333	2	-	26627737	GBM cells	viability after 5 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	1.0345689742432516	[141]	[175,135]	9	hSpCas9	negative selection	892226
201266563	201266586	2	+	26627737	GBM cells	viability after 5 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.27866256271250345	[448]	[170,225]	-4	hSpCas9	negative selection	892227
201269563	201269586	2	+	26627737	GBM cells	viability after 5 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.1268164002077321	[395]	[188,199]	-2	hSpCas9	negative selection	892228
201274917	201274940	2	+	26627737	GBM cells	viability after 5 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	-0.0003139440603321386	[621]	[285,380]	0	hSpCas9	negative selection	892229
201276924	201276947	2	+	26627737	GBM cells	viability after 5 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.6090718642122892	[238]	[173,216]	8	hSpCas9	negative selection	892230
201285121	201285144	2	-	26627737	GBM cells	viability after 5 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	0.7970342608664721	[131]	[141,103]	9	hSpCas9	negative selection	892231
201258310	201258333	2	-	26627737	GBM cells	viability after 13 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.2841208031703456	[141]	[143,52]	3	hSpCas9	negative selection	974541
201266563	201266586	2	+	26627737	GBM cells	viability after 13 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.7492180022435262	[448]	[150,139]	-7	hSpCas9	negative selection	974542
201269563	201269586	2	+	26627737	GBM cells	viability after 13 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.008912826142435715	[395]	[255,178]	0	hSpCas9	negative selection	974543
201274917	201274940	2	+	26627737	GBM cells	viability after 13 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.22095897661262076	[621]	[378,404]	3	hSpCas9	negative selection	974544
201276924	201276947	2	+	26627737	GBM cells	viability after 13 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.6789704852160112	[238]	[259,164]	8	hSpCas9	negative selection	974545
201285121	201285144	2	-	26627737	GBM cells	viability after 13 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	1.0167399192818387	[131]	[177,117]	9	hSpCas9	negative selection	974546
201258310	201258333	2	-	26627737	GBM cells	viability after 21 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	-0.34906171126342656	[141]	[58,61]	-3	hSpCas9	negative selection	1056856
201266563	201266586	2	+	26627737	GBM cells	viability after 21 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.5493242046685888	[448]	[173,159]	-5	hSpCas9	negative selection	1056857
201269563	201269586	2	+	26627737	GBM cells	viability after 21 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.15957620070343004	[395]	[189,194]	-1	hSpCas9	negative selection	1056858
201274917	201274940	2	+	26627737	GBM cells	viability after 21 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.5342345544889249	[621]	[515,464]	5	hSpCas9	negative selection	1056859
201276924	201276947	2	+	26627737	GBM cells	viability after 21 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.7480654476138802	[238]	[227,208]	7	hSpCas9	negative selection	1056860
201285121	201285144	2	-	26627737	GBM cells	viability after 21 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	1.0575873975012842	[131]	[142,154]	9	hSpCas9	negative selection	1056861
201258310	201258333	2	-	26627737	RPE1	viability after 9 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	1.2169986919949212	[270]	[153,252]	7	hSpCas9	negative selection	1139171
201266563	201266586	2	+	26627737	RPE1	viability after 9 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.14551488810100632	[1323]	[423,502]	1	hSpCas9	negative selection	1139172
201269563	201269586	2	+	26627737	RPE1	viability after 9 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-1.4633887432365476	[2304]	[138,419]	-8	hSpCas9	negative selection	1139173
201274917	201274940	2	+	26627737	RPE1	viability after 9 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.3475951218323243	[1649]	[710,587]	2	hSpCas9	negative selection	1139174
201276924	201276947	2	+	26627737	RPE1	viability after 9 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.7392188252587102	[880]	[259,718]	5	hSpCas9	negative selection	1139175
201285121	201285144	2	-	26627737	RPE1	viability after 9 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	1.1214028379289114	[183]	[99,157]	7	hSpCas9	negative selection	1139176
201258310	201258333	2	-	26627737	RPE1	viability after 12 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	1.3271823821548199	[270]	[154,211]	7	hSpCas9	negative selection	1221486
201266563	201266586	2	+	26627737	RPE1	viability after 12 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.4479446969637112	[1323]	[356,620]	3	hSpCas9	negative selection	1221487
201269563	201269586	2	+	26627737	RPE1	viability after 12 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-2.3366244548401434	[2304]	[125,118]	-9	hSpCas9	negative selection	1221488
201274917	201274940	2	+	26627737	RPE1	viability after 12 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	-0.02452192998513203	[1649]	[446,423]	0	hSpCas9	negative selection	1221489
201276924	201276947	2	+	26627737	RPE1	viability after 12 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.6107939928080474	[880]	[291,434]	4	hSpCas9	negative selection	1221490
201285121	201285144	2	-	26627737	RPE1	viability after 12 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	0.8956633001488365	[183]	[90,92]	5	hSpCas9	negative selection	1221491
201258310	201258333	2	-	26627737	RPE1	viability after 15 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	1.1994950152979151	[270]	[200,151]	7	hSpCas9	negative selection	1303801
201266563	201266586	2	+	26627737	RPE1	viability after 15 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.07804230226669118	[1323]	[431,359]	0	hSpCas9	negative selection	1303802
201269563	201269586	2	+	26627737	RPE1	viability after 15 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-2.289843193549531	[2304]	[57,205]	-8	hSpCas9	negative selection	1303803
201274917	201274940	2	+	26627737	RPE1	viability after 15 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.48235186752657677	[1649]	[676,627]	3	hSpCas9	negative selection	1303804
201276924	201276947	2	+	26627737	RPE1	viability after 15 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.4519477944220889	[880]	[205,470]	3	hSpCas9	negative selection	1303805
201285121	201285144	2	-	26627737	RPE1	viability after 15 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	1.232798412159003	[183]	[131,112]	7	hSpCas9	negative selection	1303806
201258310	201258333	2	-	26627737	RPE1	viability after 18 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	1.1163542538231197	[270]	[130,187]	6	hSpCas9	negative selection	1386116
201266563	201266586	2	+	26627737	RPE1	viability after 18 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.1407029118984524	[1323]	[230,567]	0	hSpCas9	negative selection	1386117
201269563	201269586	2	+	26627737	RPE1	viability after 18 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-1.9816964630784955	[2304]	[69,250]	-8	hSpCas9	negative selection	1386118
201274917	201274940	2	+	26627737	RPE1	viability after 18 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.06190186191698177	[1649]	[429,501]	0	hSpCas9	negative selection	1386119
201276924	201276947	2	+	26627737	RPE1	viability after 18 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.2747420626399454	[880]	[203,376]	1	hSpCas9	negative selection	1386120
201285121	201285144	2	-	26627737	RPE1	viability after 18 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	1.2552822359794187	[183]	[104,132]	7	hSpCas9	negative selection	1386121
201258310	201258333	2	-	26627737	HeLa	viability after 8 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	-0.6688624039543826	[549]	[123,233,91]	-6	hSpCas9	negative selection	1468431
201266563	201266586	2	+	26627737	HeLa	viability after 8 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.15347351116749175	[784]	[335,229,357]	-1	hSpCas9	negative selection	1468432
201269563	201269586	2	+	26627737	HeLa	viability after 8 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.17337538758676507	[703]	[303,289,230]	-2	hSpCas9	negative selection	1468433
201274917	201274940	2	+	26627737	HeLa	viability after 8 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.1429950479174853	[1069]	[418,389,698]	1	hSpCas9	negative selection	1468434
201276924	201276947	2	+	26627737	HeLa	viability after 8 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.12664696421828903	[418]	[325,157,144]	1	hSpCas9	negative selection	1468435
201285121	201285144	2	-	26627737	HeLa	viability after 8 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	0.738167371154612	[242]	[138,206,174]	6	hSpCas9	negative selection	1468436
201258310	201258333	2	-	26627737	HeLa	viability after 12 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	-0.2727949803439281	[549]	[86,201,270]	-2	hSpCas9	negative selection	1550746
201266563	201266586	2	+	26627737	HeLa	viability after 12 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.24776789909996222	[784]	[486,229,457]	2	hSpCas9	negative selection	1550747
201269563	201269586	2	+	26627737	HeLa	viability after 12 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.03385010665226451	[703]	[218,233,402]	0	hSpCas9	negative selection	1550748
201274917	201274940	2	+	26627737	HeLa	viability after 12 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.26296858550296887	[1069]	[470,455,670]	2	hSpCas9	negative selection	1550749
201276924	201276947	2	+	26627737	HeLa	viability after 12 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.16686197397432362	[418]	[136,217,223]	1	hSpCas9	negative selection	1550750
201285121	201285144	2	-	26627737	HeLa	viability after 12 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	0.3313581186784681	[242]	[169,119,90]	3	hSpCas9	negative selection	1550751
201258310	201258333	2	-	26627737	HeLa	viability after 15 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	-0.2645306567578726	[549]	[79,312,165]	-2	hSpCas9	negative selection	1633061
201266563	201266586	2	+	26627737	HeLa	viability after 15 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.021242929557577228	[784]	[354,154,473]	0	hSpCas9	negative selection	1633062
201269563	201269586	2	+	26627737	HeLa	viability after 15 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	0.10783148905102835	[703]	[270,286,373]	0	hSpCas9	negative selection	1633063
201274917	201274940	2	+	26627737	HeLa	viability after 15 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.4391815756344497	[1069]	[412,662,706]	3	hSpCas9	negative selection	1633064
201276924	201276947	2	+	26627737	HeLa	viability after 15 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	1.0886601876218485	[418]	[367,263,463]	7	hSpCas9	negative selection	1633065
201285121	201285144	2	-	26627737	HeLa	viability after 15 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	0.8973913076327633	[242]	[283,161,98]	6	hSpCas9	negative selection	1633066
201258310	201258333	2	-	26627737	HeLa	viability after 18 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	-0.2749737114023242	[549]	[47,262,165]	-2	hSpCas9	negative selection	1715376
201266563	201266586	2	+	26627737	HeLa	viability after 18 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.042877246340821684	[784]	[239,137,473]	0	hSpCas9	negative selection	1715377
201269563	201269586	2	+	26627737	HeLa	viability after 18 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	0.05861874369613007	[703]	[166,230,373]	0	hSpCas9	negative selection	1715378
201274917	201274940	2	+	26627737	HeLa	viability after 18 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.449574358300463	[1069]	[294,536,706]	4	hSpCas9	negative selection	1715379
201276924	201276947	2	+	26627737	HeLa	viability after 18 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	1.091121460060643	[418]	[250,214,463]	7	hSpCas9	negative selection	1715380
201285121	201285144	2	-	26627737	HeLa	viability after 18 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	0.934476318737672	[242]	[199,133,98]	7	hSpCas9	negative selection	1715381
201258310	201258333	2	-	26627737	HCT116	viability after 6 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	-0.7873226967633753	[222]	[9,25]	-4	hSpCas9	negative selection	1797691
201266563	201266586	2	+	26627737	HCT116	viability after 6 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.5600881576156673	[1879]	[106,251]	-3	hSpCas9	negative selection	1797692
201269563	201269586	2	+	26627737	HCT116	viability after 6 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	0.6853842637616175	[734]	[228,161]	4	hSpCas9	negative selection	1797693
201274917	201274940	2	+	26627737	HCT116	viability after 6 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.17819173621813078	[1173]	[193,216]	1	hSpCas9	negative selection	1797694
201276924	201276947	2	+	26627737	HCT116	viability after 6 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.3014461523842488	[701]	[242,76]	1	hSpCas9	negative selection	1797695
201285121	201285144	2	-	26627737	HCT116	viability after 6 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-1.1160459593125958	[480]	[50,25]	-6	hSpCas9	negative selection	1797696
201258310	201258333	2	-	26627737	HCT116	viability after 8 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.19862071819442728	[184]	[108,139,101]	2	hSpCas9	negative selection	1880006
201266563	201266586	2	+	26627737	HCT116	viability after 8 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.10017108502537042	[440]	[311,263,206]	1	hSpCas9	negative selection	1880007
201269563	201269586	2	+	26627737	HCT116	viability after 8 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.24339647095269523	[582]	[275,331,206]	-3	hSpCas9	negative selection	1880008
201274917	201274940	2	+	26627737	HCT116	viability after 8 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.21867920062064572	[665]	[402,391,484]	2	hSpCas9	negative selection	1880009
201276924	201276947	2	+	26627737	HCT116	viability after 8 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	-0.02088919317125154	[331]	[154,247,137]	0	hSpCas9	negative selection	1880010
201285121	201285144	2	-	26627737	HCT116	viability after 8 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.0746805022781552	[245]	[111,157,115]	-1	hSpCas9	negative selection	1880011
201258310	201258333	2	-	26627737	HCT116	viability after 9 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.7702579249847846	[222]	[162,52]	5	hSpCas9	negative selection	1962321
201266563	201266586	2	+	26627737	HCT116	viability after 9 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.9312250711687	[1879]	[484,87]	-6	hSpCas9	negative selection	1962322
201269563	201269586	2	+	26627737	HCT116	viability after 9 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	1.2060965560476538	[734]	[387,503]	7	hSpCas9	negative selection	1962323
201274917	201274940	2	+	26627737	HCT116	viability after 9 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.6330134514971083	[1173]	[851,196]	4	hSpCas9	negative selection	1962324
201276924	201276947	2	+	26627737	HCT116	viability after 9 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	-2.6473512677984896	[701]	[44,17]	-9	hSpCas9	negative selection	1962325
201285121	201285144	2	-	26627737	HCT116	viability after 9 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-1.1189596152529666	[480]	[33,78]	-7	hSpCas9	negative selection	1962326
201258310	201258333	2	-	26627737	HCT116	viability after 12 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.22498255214405505	[184]	[50,179,116]	2	hSpCas9	negative selection	2044636
201266563	201266586	2	+	26627737	HCT116	viability after 12 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.059895862603955574	[440]	[223,310,133]	0	hSpCas9	negative selection	2044637
201269563	201269586	2	+	26627737	HCT116	viability after 12 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.10201860790400741	[582]	[227,390,244]	-1	hSpCas9	negative selection	2044638
201274917	201274940	2	+	26627737	HCT116	viability after 12 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	-0.007563089992754568	[665]	[319,389,337]	0	hSpCas9	negative selection	2044639
201276924	201276947	2	+	26627737	HCT116	viability after 12 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.13051249072088933	[331]	[162,213,198]	1	hSpCas9	negative selection	2044640
201285121	201285144	2	-	26627737	HCT116	viability after 12 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	0.1937701363227434	[245]	[167,113,158]	2	hSpCas9	negative selection	2044641
201258310	201258333	2	-	26627737	HCT116	viability after 15 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.4408407474665063	[184]	[150,181,100]	4	hSpCas9	negative selection	2126951
201266563	201266586	2	+	26627737	HCT116	viability after 15 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.012382763730812596	[440]	[300,307,163]	0	hSpCas9	negative selection	2126952
201269563	201269586	2	+	26627737	HCT116	viability after 15 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.30398256708502824	[582]	[188,292,320]	-3	hSpCas9	negative selection	2126953
201274917	201274940	2	+	26627737	HCT116	viability after 15 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.2801204256419447	[665]	[620,460,331]	3	hSpCas9	negative selection	2126954
201276924	201276947	2	+	26627737	HCT116	viability after 15 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.6842067686149422	[331]	[286,344,284]	6	hSpCas9	negative selection	2126955
201285121	201285144	2	-	26627737	HCT116	viability after 15 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.4966602624889593	[245]	[80,111,104]	-5	hSpCas9	negative selection	2126956
201258310	201258333	2	-	26627737	HCT116	viability after 18 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.3321894830649678	[184]	[186,45,108]	3	hSpCas9	negative selection	2209266
201266563	201266586	2	+	26627737	HCT116	viability after 18 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.16917156150391488	[440]	[181,401,118]	1	hSpCas9	negative selection	2209267
201269563	201269586	2	+	26627737	HCT116	viability after 18 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.9629617947941246	[582]	[149,148,133]	-7	hSpCas9	negative selection	2209268
201274917	201274940	2	+	26627737	HCT116	viability after 18 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.20826168786670518	[665]	[160,577,362]	1	hSpCas9	negative selection	2209269
201276924	201276947	2	+	26627737	HCT116	viability after 18 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.3785267296445532	[331]	[176,289,150]	3	hSpCas9	negative selection	2209270
201285121	201285144	2	-	26627737	HCT116	viability after 18 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.2300126404985215	[245]	[71,80,154]	-2	hSpCas9	negative selection	2209271
201266496	201266519	2	+	24336569	HL60	viability	AGCAGAAATCTTTATGATATTGG	CASP8	ENSG00000064012	-0.13605907590180988	[376]	[725]	-1	hSpCas9	negative selection	2254506
201266522	201266545	2	+	24336569	HL60	viability	ACAACTGGACAGTGAAGATCTGG	CASP8	ENSG00000064012	-0.6811538870966053	[959]	[1266]	-6	hSpCas9	negative selection	2254507
201266545	201266568	2	-	24336569	HL60	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	-0.5377353783728656	[626]	[913]	-5	hSpCas9	negative selection	2254508
201266558	201266581	2	-	24336569	HL60	viability	GCGGAATGTAGTCCAGGCTCAGG	CASP8	ENSG00000064012	0.7932334906491745	[573]	[2104]	6	hSpCas9	negative selection	2254509
201266563	201266586	2	+	24336569	HL60	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.3151213480611583	[524]	[892]	-3	hSpCas9	negative selection	2254510
201266577	201266600	2	-	24336569	HL60	viability	ATGGGTTCTTGCTTCCTTTGCGG	CASP8	ENSG00000064012	0.43931422172756995	[405]	[1164]	4	hSpCas9	negative selection	2254511
201266582	201266605	2	+	24336569	HL60	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.8059537508027954	[362]	[1342]	6	hSpCas9	negative selection	2254512
201266595	201266618	2	-	24336569	HL60	viability	AACATCAAGGCATCCTTGATGGG	CASP8	ENSG00000064012	0.5768206321059501	[389]	[1230]	5	hSpCas9	negative selection	2254513
201266608	201266631	2	-	24336569	HL60	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-1.1388515827864163	[358]	[344]	-8	hSpCas9	negative selection	2254514
201266654	201266677	2	+	24336569	HL60	viability	AAGCAATCTGTCCTTCCTGAAGG	CASP8	ENSG00000064012	-0.06501357984830203	[217]	[440]	0	hSpCas9	negative selection	2254515
201266496	201266519	2	+	24336569	KBM7	viability	AGCAGAAATCTTTATGATATTGG	CASP8	ENSG00000064012	0.7827983218035603	[295]	[1388]	7	hSpCas9	negative selection	2321683
201266522	201266545	2	+	24336569	KBM7	viability	ACAACTGGACAGTGAAGATCTGG	CASP8	ENSG00000064012	1.4690206100395644	[542]	[4099]	9	hSpCas9	negative selection	2321684
201266545	201266568	2	-	24336569	KBM7	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	1.9472073266800476	[277]	[2923]	9	hSpCas9	negative selection	2321685
201266558	201266581	2	-	24336569	KBM7	viability	GCGGAATGTAGTCCAGGCTCAGG	CASP8	ENSG00000064012	1.5936583196453655	[512]	[4222]	9	hSpCas9	negative selection	2321686
201266563	201266586	2	+	24336569	KBM7	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.9811939987519341	[587]	[3165]	8	hSpCas9	negative selection	2321687
201266577	201266600	2	-	24336569	KBM7	viability	ATGGGTTCTTGCTTCCTTTGCGG	CASP8	ENSG00000064012	1.3028928799947632	[302]	[2038]	9	hSpCas9	negative selection	2321688
201266582	201266605	2	+	24336569	KBM7	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	1.5293655672234518	[204]	[1613]	9	hSpCas9	negative selection	2321689
201266595	201266618	2	-	24336569	KBM7	viability	AACATCAAGGCATCCTTGATGGG	CASP8	ENSG00000064012	0.11532893776115116	[790]	[2336]	1	hSpCas9	negative selection	2321690
201266608	201266631	2	-	24336569	KBM7	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	1.3955468565305438	[238]	[1714]	9	hSpCas9	negative selection	2321691
201266654	201266677	2	+	24336569	KBM7	viability	AAGCAATCTGTCCTTCCTGAAGG	CASP8	ENSG00000064012	0.9198973716804746	[105]	[546]	7	hSpCas9	negative selection	2321692
201266562	201266586	2	+	24717434	HeLa	essential genes for diphteria toxin toxicity	AGCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.6980324864741554	[4033,4668,3549]	[0,0,0]	-6	hSpCas9	positive selection	2380666
201266679	201266704	2	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CTGCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.07451566217223764	[2640,2242,3069]	[0,0,0]	0	hSpCas9	positive selection	2380667
201272660	201272685	2	+	24717434	HeLa	essential genes for diphteria toxin toxicity	AGATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.6737836411069709	[3828,4270,3937]	[0,0,0]	-6	hSpCas9	positive selection	2380668
201266562	201266586	2	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	2.6703537853628787	[4033,4668,3549]	[0,28,0]	5	hSpCas9	positive selection	2381813
201266562	201266586	2	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	2.6703537853628787	[4033,4668,3549]	[0,28,0]	5	hSpCas9	positive selection	2381814
201266679	201266704	2	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTGCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.07395286569056946	[2640,2242,3069]	[0,0,0]	-1	hSpCas9	positive selection	2381815
201266679	201266704	2	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTGCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.07395286569056946	[2640,2242,3069]	[0,0,0]	-1	hSpCas9	positive selection	2381816
201272660	201272685	2	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.6741653689309175	[3828,4270,3937]	[0,0,0]	-6	hSpCas9	positive selection	2381817
201272660	201272685	2	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AGATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.6741653689309175	[3828,4270,3937]	[0,0,0]	-6	hSpCas9	positive selection	2381818
201257867	201257890	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGGGTTATTATTACTAAATGG	CASP8	ENSG00000064012	-0.09635857226829472	[56,137]	[9,30]	0	dCas9-VP64	positive selection	2393155
201257922	201257945	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAAACTAAAGCCCGAGCGCTGG	CASP8	ENSG00000064012	-0.5493547037549111	[10,64]	[4,5]	-3	dCas9-VP64	positive selection	2393156
201257848	201257871	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCATATTACTTGCCACCGACAGG	CASP8	ENSG00000064012	-2.980241783263219	[312,41]	[2,5]	-9	dCas9-VP64	positive selection	2393157
201247092	201247115	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCAGGAGAATTGCTTGAGCTGG	CASP8	ENSG00000064012	-0.19954682720326655	[3,28]	[2,1]	-1	dCas9-VP64	positive selection	2401400
201260314	201260337	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCATCCAAAGTCACAGCCAGGG	CASP8	ENSG00000064012	-0.5552303893187602	[189,218]	[13,47]	-3	dCas9-VP64	positive selection	2461298
201260375	201260398	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAAAAGGCCTGGTGGTCCAGG	CASP8	ENSG00000064012	3.4759877392663068	[9,60]	[118,57]	9	dCas9-VP64	positive selection	2461299
201260357	201260380	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGCCCTGCGTGCGGTCTCCTGG	CASP8	ENSG00000064012	-1.5353201345546967	[353,152]	[18,17]	-8	dCas9-VP64	positive selection	2461300
201257867	201257890	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGGGTTATTATTACTAAATGG	CASP8	ENSG00000064012	-0.056016513661029166	[61,158]	[16,49]	0	dCas9-VP64	positive selection	2488410
201257922	201257945	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAAACTAAAGCCCGAGCGCTGG	CASP8	ENSG00000064012	-1.5230069567687154	[62,156]	[9,13]	-9	dCas9-VP64	positive selection	2488411
201257848	201257871	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCATATTACTTGCCACCGACAGG	CASP8	ENSG00000064012	0.12754543545739025	[135,65]	[41,29]	1	dCas9-VP64	positive selection	2488412
201247092	201247115	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCAGGAGAATTGCTTGAGCTGG	CASP8	ENSG00000064012	-0.014077665466813771	[22,101]	[15,22]	0	dCas9-VP64	positive selection	2496655
201260314	201260337	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCATCCAAAGTCACAGCCAGGG	CASP8	ENSG00000064012	-1.3056670068854608	[105,199]	[18,19]	-9	dCas9-VP64	positive selection	2556553
201260375	201260398	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAAAAGGCCTGGTGGTCCAGG	CASP8	ENSG00000064012	-0.2565265542358184	[32,68]	[9,16]	-2	dCas9-VP64	positive selection	2556554
201260357	201260380	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGCCCTGCGTGCGGTCTCCTGG	CASP8	ENSG00000064012	-0.18877671623756787	[195,191]	[50,59]	-2	dCas9-VP64	positive selection	2556555
201266468	201266491	2	+	27013184	SW480	treatment with recombinant TRAIL	TCTCCTGCCTTTTAAAAAGATGG	CASP8	ENSG00000064012	-0.4557615755637564	[118,91]	[14,59]	-2	hSpCas9	positive selection	2954298
201272625	201272648	2	+	27013184	SW480	treatment with recombinant TRAIL	CTCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	3.305968743570788	[397,759]	[2425,2368]	9	hSpCas9	positive selection	2954299
201258216	201258239	2	+	27013184	SW480	treatment with recombinant TRAIL	AACAGGAAGTGAGGCCATGGAGG	CASP8	ENSG00000064012	0.7682264615000656	[6,36]	[8,23]	4	hSpCas9	positive selection	2954300
201266496	201266519	2	+	27013184	SW480	treatment with recombinant TRAIL	AGCAGAAATCTTTATGATATTGG	CASP8	ENSG00000064012	-4.455151756415011	[51,160]	[1,1]	-9	hSpCas9	positive selection	2954301
201272643	201272666	2	+	27013184	SW480	treatment with recombinant TRAIL	GCTGGATATTTTCATAGAGATGG	CASP8	ENSG00000064012	3.5438158190888336	[43,37]	[61,414]	9	hSpCas9	positive selection	2954302
201284795	201284818	2	+	27013184	SW480	treatment with recombinant TRAIL	TGTTCAAATTTCACTTTTCAGGG	CASP8	ENSG00000064012	0.8708597599146141	[149,119]	[55,180]	4	hSpCas9	positive selection	2954303
201284979	201285002	2	+	27013184	SW480	treatment with recombinant TRAIL	CATCTATGGCACTGATGGACAGG	CASP8	ENSG00000064012	4.356847753173754	[603,798]	[5731,6686]	9	hSpCas9	positive selection	2954304
201284982	201285005	2	+	27013184	SW480	treatment with recombinant TRAIL	CTATGGCACTGATGGACAGGAGG	CASP8	ENSG00000064012	3.4621083111593056	[368,635]	[2393,2246]	9	hSpCas9	positive selection	2954305
201276918	201276941	2	+	27013184	SW480	treatment with recombinant TRAIL	TGCCCAAACTTCACAGCATTAGG	CASP8	ENSG00000064012	-0.671756382684925	[245,571]	[58,174]	-3	hSpCas9	positive selection	2954306
201285016	201285039	2	+	27013184	SW480	treatment with recombinant TRAIL	GAGCTGACATCTCAGTTCACTGG	CASP8	ENSG00000064012	4.37089243919287	[22,53]	[413,213]	9	hSpCas9	positive selection	2954307
201266681	201266704	2	+	27013184	SW480	treatment with recombinant TRAIL	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	3.254775166177948	[148,269]	[560,1238]	9	hSpCas9	positive selection	2954308
201266714	201266737	2	+	27013184	SW480	treatment with recombinant TRAIL	TACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	5.282239022607926	[48,178]	[1431,2365]	9	hSpCas9	positive selection	2954309
201285078	201285101	2	+	27013184	SW480	treatment with recombinant TRAIL	TTTTATTCAGGCTTGTCAGGGGG	CASP8	ENSG00000064012	1.6501206627116727	[236,336]	[281,525]	7	hSpCas9	positive selection	2954310
201266717	201266740	2	+	27013184	SW480	treatment with recombinant TRAIL	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	3.619636395673534	[91,120]	[470,681]	9	hSpCas9	positive selection	2954311
201276929	201276952	2	+	27013184	SW480	treatment with recombinant TRAIL	CACAGCATTAGGGACAGGAATGG	CASP8	ENSG00000064012	2.5483600436397027	[96,74]	[233,198]	9	hSpCas9	positive selection	2954312
201276940	201276963	2	+	27013184	SW480	treatment with recombinant TRAIL	GGACAGGAATGGAACACACTTGG	CASP8	ENSG00000064012	3.645122633873295	[110,112]	[597,612]	9	hSpCas9	positive selection	2954313
201285141	201285164	2	+	27013184	SW480	treatment with recombinant TRAIL	GGAGCAACCCTATTTAGAAATGG	CASP8	ENSG00000064012	1.6076029871722457	[31,150]	[126,93]	7	hSpCas9	positive selection	2954314
201266745	201266768	2	+	27013184	SW480	treatment with recombinant TRAIL	GAAAGGGAACTTCAGACACCAGG	CASP8	ENSG00000064012	3.6784015443719005	[203,203]	[786,1610]	9	hSpCas9	positive selection	2954315
201272755	201272778	2	+	27013184	SW480	treatment with recombinant TRAIL	GACTATGAAGAATTCAGCAAAGG	CASP8	ENSG00000064012	0.022559157175059075	[184,169]	[87,63]	0	hSpCas9	positive selection	2954316
201285174	201285197	2	+	27013184	SW480	treatment with recombinant TRAIL	ACCTCAAACGAGATATATCCCGG	CASP8	ENSG00000064012	4.444562684472486	[47,38]	[298,573]	9	hSpCas9	positive selection	2954317
201266749	201266772	2	+	27013184	SW480	treatment with recombinant TRAIL	GGGAACTTCAGACACCAGGCAGG	CASP8	ENSG00000064012	2.9490576911447355	[478,505]	[1453,1897]	9	hSpCas9	positive selection	2954318
201272776	201272799	2	+	27013184	SW480	treatment with recombinant TRAIL	GGTAGAAACAACCTGACAGCCGG	CASP8	ENSG00000064012	2.006670405804373	[202,129]	[321,254]	8	hSpCas9	positive selection	2954319
201258217	201258240	2	+	27013184	SW480	treatment with recombinant TRAIL	ACAGGAAGTGAGGCCATGGAGGG	CASP8	ENSG00000064012	0.6481945794520612	[318,414]	[208,296]	3	hSpCas9	positive selection	2954320
201266497	201266520	2	+	27013184	SW480	treatment with recombinant TRAIL	GCAGAAATCTTTATGATATTGGG	CASP8	ENSG00000064012	-0.2611371567258184	[160,180]	[52,72]	-1	hSpCas9	positive selection	2954321
201272651	201272674	2	+	27013184	SW480	treatment with recombinant TRAIL	TTTTCATAGAGATGGAGAAGAGG	CASP8	ENSG00000064012	1.9092640460538617	[54,38]	[59,101]	8	hSpCas9	positive selection	2954322
201266750	201266773	2	+	27013184	SW480	treatment with recombinant TRAIL	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.5984820371637911	[301,225]	[125,243]	3	hSpCas9	positive selection	2954323
201272777	201272800	2	+	27013184	SW480	treatment with recombinant TRAIL	GTAGAAACAACCTGACAGCCGGG	CASP8	ENSG00000064012	0.8812516581899321	[429,585]	[349,466]	4	hSpCas9	positive selection	2954324
201285195	201285218	2	+	27013184	SW480	treatment with recombinant TRAIL	GGATGAGGCTGACTTTCTGCTGG	CASP8	ENSG00000064012	3.953618998805495	[374,340]	[1581,3572]	9	hSpCas9	positive selection	2954325
201266770	201266793	2	+	27013184	SW480	treatment with recombinant TRAIL	GGGCTCAAATTTCTGCCTACAGG	CASP8	ENSG00000064012	2.010397926146913	[669,754]	[887,1721]	8	hSpCas9	positive selection	2954326
201272627	201272650	2	-	27013184	SW480	treatment with recombinant TRAIL	ATCCAGCAGGTTCTAAGAGGAGG	CASP8	ENSG00000064012	0.8510667836516068	[59,55]	[48,39]	4	hSpCas9	positive selection	2954327
201285196	201285219	2	+	27013184	SW480	treatment with recombinant TRAIL	GATGAGGCTGACTTTCTGCTGGG	CASP8	ENSG00000064012	3.2148534479316804	[411,261]	[1366,1390]	9	hSpCas9	positive selection	2954328
201266773	201266796	2	+	27013184	SW480	treatment with recombinant TRAIL	CTCAAATTTCTGCCTACAGGTGG	CASP8	ENSG00000064012	-0.10952157218732708	[303,196]	[85,124]	0	hSpCas9	positive selection	2954329
201285197	201285220	2	+	27013184	SW480	treatment with recombinant TRAIL	ATGAGGCTGACTTTCTGCTGGGG	CASP8	ENSG00000064012	0.7131790514088876	[104,72]	[51,80]	3	hSpCas9	positive selection	2954330
201272640	201272663	2	-	27013184	SW480	treatment with recombinant TRAIL	TCTCTATGAAAATATCCAGCAGG	CASP8	ENSG00000064012	1.3291887081872922	[39,69]	[25,103]	6	hSpCas9	positive selection	2954331
201258230	201258253	2	-	27013184	SW480	treatment with recombinant TRAIL	GGCTCTTCTGCCTCCCTCCATGG	CASP8	ENSG00000064012	0.28914089409454125	[1022,931]	[427,644]	1	hSpCas9	positive selection	2954332
201266777	201266800	2	+	27013184	SW480	treatment with recombinant TRAIL	AATTTCTGCCTACAGGTGGGTGG	CASP8	ENSG00000064012	2.032650968153698	[726,596]	[904,1568]	8	hSpCas9	positive selection	2954333
201258251	201258274	2	-	27013184	SW480	treatment with recombinant TRAIL	TTTACTTTCAATAACCACCCTGG	CASP8	ENSG00000064012	1.3181722465061425	[183,228]	[172,286]	6	hSpCas9	positive selection	2954334
201276844	201276867	2	-	27013184	SW480	treatment with recombinant TRAIL	CCCGAGGTTTGCTTTTCATTTGG	CASP8	ENSG00000064012	1.1998123480380471	[341,388]	[280,472]	5	hSpCas9	positive selection	2954335
201258285	201258308	2	-	27013184	SW480	treatment with recombinant TRAIL	AGGGGGTGGGAAAGGCTCCCAGG	CASP8	ENSG00000064012	1.9946939363645162	[34,64]	[34,152]	8	hSpCas9	positive selection	2954336
201266443	201266466	2	-	27013184	SW480	treatment with recombinant TRAIL	ATAATCTAAGTCAAAATAAATGG	CASP8	ENSG00000064012	-5.460166319756979	[229,172]	[1,1]	-9	hSpCas9	positive selection	2954337
201285251	201285274	2	+	27013184	SW480	treatment with recombinant TRAIL	GAAACCCTGCAGAGGGAACCTGG	CASP8	ENSG00000064012	1.750864411348287	[85,190]	[51,396]	7	hSpCas9	positive selection	2954338
201258293	201258316	2	-	27013184	SW480	treatment with recombinant TRAIL	AGCAGGGAAGGGGGTGGGAAAGG	CASP8	ENSG00000064012	2.9368869132593796	[1,10]	[1,45]	9	hSpCas9	positive selection	2954339
201266545	201266568	2	-	27013184	SW480	treatment with recombinant TRAIL	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	2.4468850092005625	[190,179]	[482,372]	9	hSpCas9	positive selection	2954340
201266548	201266571	2	-	27013184	SW480	treatment with recombinant TRAIL	GTCCAGGCTCAGGAACTTGAGGG	CASP8	ENSG00000064012	3.3902953589400155	[35,138]	[354,403]	9	hSpCas9	positive selection	2954341
201284825	201284848	2	-	27013184	SW480	treatment with recombinant TRAIL	ATGAAGCTCTTCAAAGGTCGTGG	CASP8	ENSG00000064012	1.4540381928563413	[282,340]	[156,662]	6	hSpCas9	positive selection	2954342
201266549	201266572	2	-	27013184	SW480	treatment with recombinant TRAIL	AGTCCAGGCTCAGGAACTTGAGG	CASP8	ENSG00000064012	3.7768388783767533	[850,611]	[4592,4099]	9	hSpCas9	positive selection	2954343
201258220	201258243	2	+	27013184	SW480	treatment with recombinant TRAIL	GGAAGTGAGGCCATGGAGGGAGG	CASP8	ENSG00000064012	-1.1934591258459113	[60,2]	[8,2]	-5	hSpCas9	positive selection	2954344
201272652	201272675	2	+	27013184	SW480	treatment with recombinant TRAIL	TTTCATAGAGATGGAGAAGAGGG	CASP8	ENSG00000064012	2.130796312187015	[190,537]	[608,731]	8	hSpCas9	positive selection	2954345
201284898	201284921	2	+	27013184	SW480	treatment with recombinant TRAIL	TTTGAAAATCTACCAACTCATGG	CASP8	ENSG00000064012	0.8560884024050095	[20,19]	[20,8]	4	hSpCas9	positive selection	2954346
201258302	201258325	2	-	27013184	SW480	treatment with recombinant TRAIL	CACGTGCTCAGCAGGGAAGGGGG	CASP8	ENSG00000064012	-1.7870264047722244	[363,980]	[71,92]	-7	hSpCas9	positive selection	2954347
201266558	201266581	2	-	27013184	SW480	treatment with recombinant TRAIL	GCGGAATGTAGTCCAGGCTCAGG	CASP8	ENSG00000064012	3.9166486307480186	[102,287]	[676,1993]	9	hSpCas9	positive selection	2954348
201272703	201272726	2	-	27013184	SW480	treatment with recombinant TRAIL	TTTGGGCACAGACTCTTTTCAGG	CASP8	ENSG00000064012	2.2807651905026445	[280,194]	[237,889]	8	hSpCas9	positive selection	2954349
201266564	201266587	2	-	27013184	SW480	treatment with recombinant TRAIL	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	2.518046219111011	[108,206]	[158,693]	9	hSpCas9	positive selection	2954350
201272720	201272743	2	-	27013184	SW480	treatment with recombinant TRAIL	CAGCAGGCTCTTGTTGATTTGGG	CASP8	ENSG00000064012	2.9542740939021654	[9,48]	[96,86]	9	hSpCas9	positive selection	2954351
201266577	201266600	2	-	27013184	SW480	treatment with recombinant TRAIL	ATGGGTTCTTGCTTCCTTTGCGG	CASP8	ENSG00000064012	2.244227908215726	[499,651]	[1103,1248]	8	hSpCas9	positive selection	2954352
201272721	201272744	2	-	27013184	SW480	treatment with recombinant TRAIL	TCAGCAGGCTCTTGTTGATTTGG	CASP8	ENSG00000064012	-0.37200647677134735	[527,813]	[254,168]	-2	hSpCas9	positive selection	2954353
201284862	201284885	2	-	27013184	SW480	treatment with recombinant TRAIL	GCTCTACTGTGCAGTCATCGTGG	CASP8	ENSG00000064012	3.633379662368956	[154,244]	[1113,957]	9	hSpCas9	positive selection	2954354
201266595	201266618	2	-	27013184	SW480	treatment with recombinant TRAIL	AACATCAAGGCATCCTTGATGGG	CASP8	ENSG00000064012	0.8942244477839438	[252,593]	[199,508]	4	hSpCas9	positive selection	2954355
201272736	201272759	2	-	27013184	SW480	treatment with recombinant TRAIL	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	4.955745234422872	[94,121]	[1821,888]	9	hSpCas9	positive selection	2954356
201266608	201266631	2	-	27013184	SW480	treatment with recombinant TRAIL	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	4.540644788172377	[19,114]	[694,550]	9	hSpCas9	positive selection	2954357
201284955	201284978	2	-	27013184	SW480	treatment with recombinant TRAIL	TGCCCTTGTCTCCATGGGAGAGG	CASP8	ENSG00000064012	-0.541275549086891	[226,430]	[72,125]	-2	hSpCas9	positive selection	2954358
201266621	201266644	2	-	27013184	SW480	treatment with recombinant TRAIL	TTCTCTTTTCCTGGAGTCTCTGG	CASP8	ENSG00000064012	-0.6644524159859034	[518,384]	[56,220]	-3	hSpCas9	positive selection	2954359
201284960	201284983	2	-	27013184	SW480	treatment with recombinant TRAIL	GATGATGCCCTTGTCTCCATGGG	CASP8	ENSG00000064012	5.254473659295405	[999,1348]	[17677,21103]	9	hSpCas9	positive selection	2954360
201266665	201266688	2	-	27013184	SW480	treatment with recombinant TRAIL	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	3.4128623011809953	[69,126]	[431,453]	9	hSpCas9	positive selection	2954361
201285005	201285028	2	-	27013184	SW480	treatment with recombinant TRAIL	AGATGTCAGCTCATAGATGGGGG	CASP8	ENSG00000064012	1.7557230463161422	[20,101]	[45,138]	7	hSpCas9	positive selection	2954362
201266669	201266692	2	-	27013184	SW480	treatment with recombinant TRAIL	TTCGGAAGAGCAGCTCCTTCAGG	CASP8	ENSG00000064012	0.9836639027736688	[256,241]	[210,216]	4	hSpCas9	positive selection	2954363
201285006	201285029	2	-	27013184	SW480	treatment with recombinant TRAIL	GAGATGTCAGCTCATAGATGGGG	CASP8	ENSG00000064012	2.335352756277042	[42,72]	[70,197]	8	hSpCas9	positive selection	2954364
201258233	201258256	2	+	27013184	SW480	treatment with recombinant TRAIL	TGGAGGGAGGCAGAAGAGCCAGG	CASP8	ENSG00000064012	2.481579789528163	[30,47]	[28,184]	9	hSpCas9	positive selection	2954365
201266507	201266530	2	+	27013184	SW480	treatment with recombinant TRAIL	TTATGATATTGGGGAACAACTGG	CASP8	ENSG00000064012	1.85614841068558	[198,87]	[176,309]	8	hSpCas9	positive selection	2954366
201272661	201272684	2	+	27013184	SW480	treatment with recombinant TRAIL	GATGGAGAAGAGGGTCATCCTGG	CASP8	ENSG00000064012	-2.0707754094482875	[56,150]	[1,21]	-7	hSpCas9	positive selection	2954367
201284913	201284936	2	+	27013184	SW480	treatment with recombinant TRAIL	ACTCATGGACCACAGTAACATGG	CASP8	ENSG00000064012	4.087660093206821	[145,260]	[1155,1881]	9	hSpCas9	positive selection	2954368
201266687	201266710	2	-	27013184	SW480	treatment with recombinant TRAIL	GCAAATCCAGTCTATTAATTCGG	CASP8	ENSG00000064012	0.9977229280798454	[68,161]	[31,186]	5	hSpCas9	positive selection	2954369
201285007	201285030	2	-	27013184	SW480	treatment with recombinant TRAIL	TGAGATGTCAGCTCATAGATGGG	CASP8	ENSG00000064012	2.303151724791043	[1,6]	[11,4]	8	hSpCas9	positive selection	2954370
201266716	201266739	2	-	27013184	SW480	treatment with recombinant TRAIL	CTCCTTTCTAGTGTTTAGGTAGG	CASP8	ENSG00000064012	3.9672534998437614	[86,157]	[644,1033]	9	hSpCas9	positive selection	2954371
201266720	201266743	2	-	27013184	SW480	treatment with recombinant TRAIL	TCTCCTCCTTTCTAGTGTTTAGG	CASP8	ENSG00000064012	3.03249116053389	[354,289]	[1197,1078]	9	hSpCas9	positive selection	2954372
201266763	201266786	2	-	27013184	SW480	treatment with recombinant TRAIL	GCAGAAATTTGAGCCCTGCCTGG	CASP8	ENSG00000064012	3.3191424884959533	[256,200]	[736,1366]	9	hSpCas9	positive selection	2954373
201285049	201285072	2	-	27013184	SW480	treatment with recombinant TRAIL	TTGGGTTTTCCAGCAAGGGAAGG	CASP8	ENSG00000064012	0.7246697984409154	[453,1133]	[424,714]	3	hSpCas9	positive selection	2954374
201266785	201266808	2	-	27013184	SW480	treatment with recombinant TRAIL	GGGAGTTTCCACCCACCTGTAGG	CASP8	ENSG00000064012	3.034808169100072	[60,172]	[259,589]	9	hSpCas9	positive selection	2954375
201285067	201285090	2	-	27013184	SW480	treatment with recombinant TRAIL	GCCTGAATAAAAAACACTTTGGG	CASP8	ENSG00000064012	1.5680209679586763	[416,605]	[431,944]	7	hSpCas9	positive selection	2954376
201285068	201285091	2	-	27013184	SW480	treatment with recombinant TRAIL	AGCCTGAATAAAAAACACTTTGG	CASP8	ENSG00000064012	0.6840338912299992	[22,48]	[5,49]	3	hSpCas9	positive selection	2954377
201258237	201258260	2	+	27013184	SW480	treatment with recombinant TRAIL	GGGAGGCAGAAGAGCCAGGGTGG	CASP8	ENSG00000064012	-3.087327119510394	[167,129]	[5,9]	-9	hSpCas9	positive selection	2954378
201272662	201272685	2	+	27013184	SW480	treatment with recombinant TRAIL	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	3.9510161941941413	[193,370]	[1749,1950]	9	hSpCas9	positive selection	2954379
201284944	201284967	2	+	27013184	SW480	treatment with recombinant TRAIL	ATCTGCTGTATCCTCTCCCATGG	CASP8	ENSG00000064012	3.468223574408087	[207,251]	[987,1232]	9	hSpCas9	positive selection	2954380
201285148	201285171	2	-	27013184	SW480	treatment with recombinant TRAIL	GATAAATCCATTTCTAAATAGGG	CASP8	ENSG00000064012	4.018851684173492	[27,91]	[339,484]	9	hSpCas9	positive selection	2954381
201258267	201258290	2	+	27013184	SW480	treatment with recombinant TRAIL	AAGTAAAAGAAACTTCTTCCTGG	CASP8	ENSG00000064012	0.49231431264158676	[5,11]	[1,9]	2	hSpCas9	positive selection	2954382
201266546	201266569	2	+	27013184	SW480	treatment with recombinant TRAIL	CTCCCTCAAGTTCCTGAGCCTGG	CASP8	ENSG00000064012	1.5335148577225257	[223,357]	[339,378]	7	hSpCas9	positive selection	2954383
201276843	201276866	2	+	27013184	SW480	treatment with recombinant TRAIL	ACCAAATGAAAAGCAAACCTCGG	CASP8	ENSG00000064012	2.8189131764472286	[148,25]	[176,433]	9	hSpCas9	positive selection	2954384
201284952	201284975	2	+	27013184	SW480	treatment with recombinant TRAIL	TATCCTCTCCCATGGAGACAAGG	CASP8	ENSG00000064012	1.4839441067883299	[564,636]	[598,895]	7	hSpCas9	positive selection	2954385
201285269	201285292	2	-	27013184	SW480	treatment with recombinant TRAIL	GCAAAGTGACTGGATGTACCAGG	CASP8	ENSG00000064012	3.439079193619819	[107,175]	[517,838]	9	hSpCas9	positive selection	2954386
201285291	201285314	2	-	27013184	SW480	treatment with recombinant TRAIL	GACATCGCTCTCTCAGGCTCTGG	CASP8	ENSG00000064012	3.870501063932989	[398,524]	[3039,2653]	9	hSpCas9	positive selection	2954387
201266563	201266586	2	+	27013184	SW480	treatment with recombinant TRAIL	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	4.814283472203241	[137,66]	[1200,1398]	9	hSpCas9	positive selection	2954388
201266582	201266605	2	+	27013184	SW480	treatment with recombinant TRAIL	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	3.7276563007163555	[112,144]	[659,827]	9	hSpCas9	positive selection	2954389
201276844	201276867	2	+	27013184	SW480	treatment with recombinant TRAIL	CCAAATGAAAAGCAAACCTCGGG	CASP8	ENSG00000064012	3.7193854813527287	[207,211]	[963,1517]	9	hSpCas9	positive selection	2954390
201284965	201284988	2	+	27013184	SW480	treatment with recombinant TRAIL	GGAGACAAGGGCATCATCTATGG	CASP8	ENSG00000064012	2.676331971456132	[395,362]	[898,1266]	9	hSpCas9	positive selection	2954391
201266612	201266635	2	+	27013184	SW480	treatment with recombinant TRAIL	GATGTTATTCCAGAGACTCCAGG	CASP8	ENSG00000064012	2.7322516958697127	[161,163]	[507,408]	9	hSpCas9	positive selection	2954392
201276845	201276868	2	+	27013184	SW480	treatment with recombinant TRAIL	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	3.1233327746839525	[87,91]	[234,483]	9	hSpCas9	positive selection	2954393
201284974	201284997	2	+	27013184	SW480	treatment with recombinant TRAIL	GGCATCATCTATGGCACTGATGG	CASP8	ENSG00000064012	5.325913010974482	[57,200]	[1207,3445]	9	hSpCas9	positive selection	2954394
201266687	201266710	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAATCCAGTCTATTAATTCGG	CASP8	ENSG00000064012	-0.017416533549664825	[4,4]	[4,2]	0	hSpCas9	positive selection	2976431
201266564	201266587	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.22905458967531367	[2,2]	[3,2]	5	hSpCas9	positive selection	2976432
201266751	201266774	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	-0.7019328652943883	[2,2]	[2,0]	-8	hSpCas9	positive selection	2976433
201266785	201266808	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGAGTTTCCACCCACCTGTAGG	CASP8	ENSG00000064012	-0.22825243768247633	[3,2]	[2,1]	-3	hSpCas9	positive selection	2976434
201266687	201266710	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAATCCAGTCTATTAATTCGG	CASP8	ENSG00000064012	0.11787209015313721	[4,4]	[4,2]	2	hSpCas9	positive selection	3044289
201266564	201266587	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.01699389206659463	[2,2]	[3,0]	0	hSpCas9	positive selection	3044290
201266751	201266774	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	-0.07020936005928452	[2,2]	[2,1]	-1	hSpCas9	positive selection	3044291
201266785	201266808	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGAGTTTCCACCCACCTGTAGG	CASP8	ENSG00000064012	0.012272197771756546	[3,3]	[1,2]	0	hSpCas9	positive selection	3044292
201271542	201271565		+	24336571	A375	resistance to PLX after 7 days	AAGTGAGCAGATCAGAATTGAGG	CASP8	ENSG00000064012	-0.14469716783188002	[32,33]	[31,28]	-5	hSpCas9	positive selection	3160752
201272736	201272759		-	24336571	A375	resistance to PLX after 7 days	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.07495505358959154	[45,42]	[45,46]	2	hSpCas9	positive selection	3160753
201271600	201271623		+	24336571	A375	resistance to PLX after 7 days	ATGCAAACTGGATGATGACATGG	CASP8	ENSG00000064012	0.027244395767705876	[24,23]	[24,24]	1	hSpCas9	positive selection	3160754
201266681	201266704		+	24336571	A375	resistance to PLX after 7 days	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.34593792049731364	[3,4]	[5,5]	8	hSpCas9	positive selection	3160755
201269584	201269607		+	24336571	A375	resistance to PLX after 7 days	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.08031999804894174	[4,5]	[5,5]	2	hSpCas9	positive selection	3160757
201271596	201271619		-	24336571	A375	resistance to PLX after 7 days	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	-0.13609088658776258	[107,110]	[97,100]	-4	hSpCas9	positive selection	3160758
201266714	201266737		+	24336571	A375	resistance to PLX after 7 days	TACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	0.29259166380196244	[5,5]	[8,5]	7	hSpCas9	positive selection	3160759
201266564	201266587		-	24336571	A375	resistance to PLX after 7 days	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	-0.25409751079843257	[18,16]	[13,14]	-7	hSpCas9	positive selection	3160760
201269571	201269594		-	24336571	A375	resistance to PLX after 7 days	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.6005401990190335	[7,8]	[14,11]	9	hSpCas9	positive selection	3160761
201271542	201271565		+	24336571	A375	resistance to PLX after 14 days	AAGTGAGCAGATCAGAATTGAGG	CASP8	ENSG00000064012	-0.42713464686172586	[33,22]	[7,10]	-5	hSpCas9	positive selection	3218545
201272736	201272759		-	24336571	A375	resistance to PLX after 14 days	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.02480873007771134	[64,52]	[29,25]	0	hSpCas9	positive selection	3218546
201271600	201271623		+	24336571	A375	resistance to PLX after 14 days	ATGCAAACTGGATGATGACATGG	CASP8	ENSG00000064012	-0.7148560722171493	[29,33]	[7,9]	-8	hSpCas9	positive selection	3218547
201266681	201266704		+	24336571	A375	resistance to PLX after 14 days	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.252674814201594	[8,3]	[2,1]	-3	hSpCas9	positive selection	3218548
201269584	201269607		+	24336571	A375	resistance to PLX after 14 days	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	-0.29492823621780895	[4,5]	[1,1]	-3	hSpCas9	positive selection	3218550
201271596	201271619		-	24336571	A375	resistance to PLX after 14 days	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.5373665661638265	[116,113]	[76,79]	5	hSpCas9	positive selection	3218551
201266714	201266737		+	24336571	A375	resistance to PLX after 14 days	TACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-0.24994910825188787	[5,7]	[1,2]	-3	hSpCas9	positive selection	3218552
201266564	201266587		-	24336571	A375	resistance to PLX after 14 days	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	-0.5068068679253754	[16,17]	[5,4]	-6	hSpCas9	positive selection	3218553
201269571	201269594		-	24336571	A375	resistance to PLX after 14 days	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	1.2634750892829991	[9,7]	[8,10]	8	hSpCas9	positive selection	3218554
201271542	201271565		+	24336571	A375	viability after 7 days	AAGTGAGCAGATCAGAATTGAGG	CASP8	ENSG00000064012	0.02418261162846891	[34]	[32,33]	0	hSpCas9	negative selection	3276338
201272736	201272759		-	24336571	A375	viability after 7 days	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.21751209031293617	[54]	[45,42]	-3	hSpCas9	negative selection	3276339
201271600	201271623		+	24336571	A375	viability after 7 days	ATGCAAACTGGATGATGACATGG	CASP8	ENSG00000064012	1.0835142969460199	[11]	[24,23]	9	hSpCas9	negative selection	3276340
201266681	201266704		+	24336571	A375	viability after 7 days	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-1.1140249259713373	[10]	[3,4]	-9	hSpCas9	negative selection	3276341
201269584	201269607		+	24336571	A375	viability after 7 days	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	-0.4939762884998753	[8]	[4,5]	-6	hSpCas9	negative selection	3276343
201271596	201271619		-	24336571	A375	viability after 7 days	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	1.355876395739707	[44]	[107,110]	9	hSpCas9	negative selection	3276344
201266714	201266737		+	24336571	A375	viability after 7 days	TACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-0.28961547877198	[7]	[5,5]	-4	hSpCas9	negative selection	3276345
201266564	201266587		-	24336571	A375	viability after 7 days	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	1.2578424127566643	[7]	[18,16]	9	hSpCas9	negative selection	3276346
201269571	201269594		-	24336571	A375	viability after 7 days	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	-0.07308442425086153	[9]	[7,8]	-1	hSpCas9	negative selection	3276347
201271542	201271565		+	24336571	A375	viability after 14 days	AAGTGAGCAGATCAGAATTGAGG	CASP8	ENSG00000064012	-0.1957006046445351	[34]	[33,22]	-2	hSpCas9	negative selection	3334131
201272736	201272759		-	24336571	A375	viability after 14 days	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.20207715004369797	[54]	[64,52]	2	hSpCas9	negative selection	3334132
201271600	201271623		+	24336571	A375	viability after 14 days	ATGCAAACTGGATGATGACATGG	CASP8	ENSG00000064012	1.4847114364423382	[11]	[29,33]	9	hSpCas9	negative selection	3334133
201266681	201266704		+	24336571	A375	viability after 14 days	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.604952756257791	[10]	[8,3]	-6	hSpCas9	negative selection	3334134
201269584	201269607		+	24336571	A375	viability after 14 days	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	-0.4836367072858685	[8]	[4,5]	-5	hSpCas9	negative selection	3334136
201271596	201271619		-	24336571	A375	viability after 14 days	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	1.4532885418385204	[44]	[116,113]	9	hSpCas9	negative selection	3334137
201266714	201266737		+	24336571	A375	viability after 14 days	TACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-0.06621534750521008	[7]	[5,7]	0	hSpCas9	negative selection	3334138
201266564	201266587		-	24336571	A375	viability after 14 days	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	1.2341741116452094	[7]	[16,17]	9	hSpCas9	negative selection	3334139
201269571	201269594		-	24336571	A375	viability after 14 days	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	-0.050784447459459536	[9]	[9,7]	0	hSpCas9	negative selection	3334140
201269571	201269594	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	-0.5720856314849662	[219,234]	[0,0]	-4	hSpCas9	positive selection	3341136
201269584	201269607	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	7.911112600156357	[175,202]	[594,0]	9	hSpCas9	positive selection	3341137
201266564	201266587	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	2.7640070679135387	[25,18]	[0,0]	8	hSpCas9	positive selection	3341138
201266681	201266704	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	1.4759664979211755	[54,54]	[0,0]	6	hSpCas9	positive selection	3360384
201272736	201272759	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	1.0675016525658179	[72,72]	[0,0]	5	hSpCas9	positive selection	3360385
201271596	201271619	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	-2.4274224089757905	[822,822]	[0,0]	-9	hSpCas9	positive selection	3360386
201266687	201266710	2	-	26780180	HT29	viability (Avana library 4 designs)	GCAAATCCAGTCTATTAATTCGG	CASP8	ENSG00000064012	-0.429166915714846	[]	[]	-6	hSpCas9	negative selection	3412712
201266563	201266586	2	+	26780180	HT29	viability (Avana library 4 designs)	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.406175984612765	[]	[]	1	hSpCas9	negative selection	3412713
201266750	201266773	2	+	26780180	HT29	viability (Avana library 4 designs)	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	1.14101591302062	[]	[]	4	hSpCas9	negative selection	3412714
201266785	201266808	2	-	26780180	HT29	viability (Avana library 4 designs)	GGGAGTTTCCACCCACCTGTAGG	CASP8	ENSG00000064012	1.86418180783737	[]	[]	7	hSpCas9	negative selection	3412715
201266750	201266773	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	2.6109339488068	[]	[]	4	hSpCas9	negative selection	3488316
201266563	201266586	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	3.12825399592355	[]	[]	5	hSpCas9	negative selection	3488317
201266785	201266808	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGAGTTTCCACCCACCTGTAGG	CASP8	ENSG00000064012	2.08835260135974	[]	[]	3	hSpCas9	negative selection	3488318
201266687	201266710	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAATCCAGTCTATTAATTCGG	CASP8	ENSG00000064012	-6.81058667898519	[]	[]	-6	hSpCas9	negative selection	3488319
201266630	201266653	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGGAAAAGAGAATGTTGGAGG	CASP8	ENSG00000064012	4.60866323667194	[]	[]	7	hSpCas9	negative selection	3488320
201266774	201266797	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	-0.0274930964570986	[]	[]	0	hSpCas9	negative selection	3488321
201266750	201266773	2	+	26780180	A375	viability (Avana lentiGuide)	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	-6.40606072703991	[]	[]	-9	hSpCas9	negative selection	3596975
201266563	201266586	2	+	26780180	A375	viability (Avana lentiGuide)	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.548785916695531	[]	[]	-1	hSpCas9	negative selection	3596976
201266785	201266808	2	-	26780180	A375	viability (Avana lentiGuide)	GGGAGTTTCCACCCACCTGTAGG	CASP8	ENSG00000064012	-2.1025392261926	[]	[]	-4	hSpCas9	negative selection	3596977
201266687	201266710	2	-	26780180	A375	viability (Avana lentiGuide)	GCAAATCCAGTCTATTAATTCGG	CASP8	ENSG00000064012	-5.88316709757785	[]	[]	-8	hSpCas9	negative selection	3596978
201266630	201266653	2	+	26780180	A375	viability (Avana lentiGuide)	CCAGGAAAAGAGAATGTTGGAGG	CASP8	ENSG00000064012	-5.93630193028879	[]	[]	-8	hSpCas9	negative selection	3596979
201266774	201266797	2	+	26780180	A375	viability (Avana lentiGuide)	TCAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	-3.38381052793303	[]	[]	-6	hSpCas9	negative selection	3596980
201266750	201266773	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	-0.048866410013744546	[4]	[5,3]	-1	hSpCas9	positive selection	3705634
201266563	201266586	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.19419768159549722	[4]	[4,2]	-3	hSpCas9	positive selection	3705635
201266785	201266808	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGAGTTTCCACCCACCTGTAGG	CASP8	ENSG00000064012	-0.02422289536613581	[4]	[4,4]	0	hSpCas9	positive selection	3705636
201266687	201266710	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAATCCAGTCTATTAATTCGG	CASP8	ENSG00000064012	-0.44930893273269557	[6]	[4,3]	-6	hSpCas9	positive selection	3705637
201266630	201266653	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGGAAAAGAGAATGTTGGAGG	CASP8	ENSG00000064012	0.22107412561643908	[4]	[5,4]	6	hSpCas9	positive selection	3705638
201266774	201266797	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.054760621586217195	[6]	[6,6]	1	hSpCas9	positive selection	3705639
201266750	201266773	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.0017303855034946358	[4]	[3,3]	0	hSpCas9	positive selection	3814241
201266563	201266586	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.5193910605002532	[4]	[1,3]	-6	hSpCas9	positive selection	3814242
201266785	201266808	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGAGTTTCCACCCACCTGTAGG	CASP8	ENSG00000064012	-0.11159364650787718	[5]	[5,2]	-1	hSpCas9	positive selection	3814243
201266687	201266710	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAATCCAGTCTATTAATTCGG	CASP8	ENSG00000064012	0.38297242044726365	[6]	[6,7]	9	hSpCas9	positive selection	3814244
201266630	201266653	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGGAAAAGAGAATGTTGGAGG	CASP8	ENSG00000064012	0.4483404545258473	[5]	[6,5]	9	hSpCas9	positive selection	3814245
201266774	201266797	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.3232977515455746	[6]	[7,6]	8	hSpCas9	positive selection	3814246
201272736	201272759	2	-	26780180	A375	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	1.2621592145909	[]	[]	6	hSpCas9	negative selection	3922541
201266681	201266704	2	+	26780180	A375	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.502137827747375	[]	[]	1	hSpCas9	negative selection	3922542
201269584	201269607	2	+	26780180	A375	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.0356005824015085	[]	[]	0	hSpCas9	negative selection	3922543
201271596	201271619	2	-	26780180	A375	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	-0.180650704546865	[]	[]	-5	hSpCas9	negative selection	3922544
201266564	201266587	2	-	26780180	A375	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.852544839092678	[]	[]	3	hSpCas9	negative selection	3922545
201269571	201269594	2	-	26780180	A375	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.769444273292384	[]	[]	3	hSpCas9	negative selection	3922546
201272736	201272759	2	-	26780180	HT29	viability (GeCKOv2 library)	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	1.5605170178999	[]	[]	8	hSpCas9	negative selection	4030507
201266681	201266704	2	+	26780180	HT29	viability (GeCKOv2 library)	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.895455325988056	[]	[]	4	hSpCas9	negative selection	4030508
201269584	201269607	2	+	26780180	HT29	viability (GeCKOv2 library)	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	-0.0466683034574443	[]	[]	-1	hSpCas9	negative selection	4030509
201271596	201271619	2	-	26780180	HT29	viability (GeCKOv2 library)	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	-0.0547377359365846	[]	[]	-2	hSpCas9	negative selection	4030510
201266564	201266587	2	-	26780180	HT29	viability (GeCKOv2 library)	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	1.12592549741857	[]	[]	5	hSpCas9	negative selection	4030511
201269571	201269594	2	-	26780180	HT29	viability (GeCKOv2 library)	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	1.27055815150753	[]	[]	6	hSpCas9	negative selection	4030512
201271542	201271565	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGTGAGCAGATCAGAATTGAGG	CASP8	ENSG00000064012	0.07410052871671874	[5]	[4,3]	2	hSpCas9	positive selection	4188845
201272736	201272759	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.2813683412424597	[5]	[4,4]	7	hSpCas9	positive selection	4188846
201271600	201271623	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGCAAACTGGATGATGACATGG	CASP8	ENSG00000064012	0.13018637746455816	[4]	[3,3]	3	hSpCas9	positive selection	4188847
201266681	201266704	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.6541272613054578	[1]	[1,0]	9	hSpCas9	positive selection	4188848
201269584	201269607	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	-0.30554952812182645	[2]	[1,0]	-6	hSpCas9	positive selection	4188850
201271596	201271619	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.28252230217253105	[6]	[4,6]	7	hSpCas9	positive selection	4188851
201266714	201266737	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-0.29087441711920525	[2]	[1,0]	-6	hSpCas9	positive selection	4188852
201266564	201266587	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.13141604847514932	[3]	[2,2]	3	hSpCas9	positive selection	4188853
201269571	201269594	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.3081692033905321	[3]	[2,3]	7	hSpCas9	positive selection	4188854
201271542	201271565	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGTGAGCAGATCAGAATTGAGG	CASP8	ENSG00000064012	1.0401091230518755	[4]	[5,3,4,3]	7	hSpCas9	positive selection	4252867
201272736	201272759	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.9483922309743957	[5]	[3,3,5,4]	6	hSpCas9	positive selection	4252868
201271600	201271623	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGCAAACTGGATGATGACATGG	CASP8	ENSG00000064012	1.0254710354174426	[4]	[4,0,4,4]	7	hSpCas9	positive selection	4252869
201266681	201266704	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.40598826456158854	[2]	[1,0,0,0]	-6	hSpCas9	positive selection	4252870
201269584	201269607	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	-0.5050615711270159	[2]	[0,0,0,0]	-7	hSpCas9	positive selection	4252872
201271596	201271619	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.981535926333029	[7]	[4,6,5,6]	7	hSpCas9	positive selection	4252873
201266714	201266737	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	0.5519424563290715	[2]	[3,1,1,0]	4	hSpCas9	positive selection	4252874
201266564	201266587	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.40121430342549447	[1]	[0,2,1,0]	3	hSpCas9	positive selection	4252875
201269571	201269594	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.2673347496053202	[1]	[2,0,0,0]	2	hSpCas9	positive selection	4252876
201269571	201269594	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.5544894372679687	[3]	[3,4]	9	hSpCas9	positive selection	4261024
201269584	201269607	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.4140264623616297	[3]	[3,3]	8	hSpCas9	positive selection	4261025
201266564	201266587	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	-0.7470627707892322	[1]	[0,0]	-9	hSpCas9	positive selection	4261026
201266681	201266704	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.816081751232742	[1]	[2,2]	9	hSpCas9	positive selection	4325302
201272736	201272759	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.39127262635538124	[2]	[0,1]	-7	hSpCas9	positive selection	4325303
201271596	201271619	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.5059074178431073	[4]	[5,5]	9	hSpCas9	positive selection	4325304
201266564	201266586	2	+	27760321	OCIAML3	viability	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.024553024761665765	[746,643]	[399,706]	0	hSpCas9	negative selection	4385827
201266608	201266630	2	-	27760321	OCIAML3	viability	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	1.8196083245576955	[79,54]	[151,225]	9	hSpCas9	negative selection	4385828
201266715	201266737	2	+	27760321	OCIAML3	viability	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-0.35317016161097303	[36,14]	[4,28]	-4	hSpCas9	negative selection	4385829
201266775	201266797	2	+	27760321	OCIAML3	viability	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.8062083590449257	[748,586]	[827,1010]	8	hSpCas9	negative selection	4385830
201272626	201272648	2	+	27760321	OCIAML3	viability	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	0.426241367715158	[429,398]	[380,506]	5	hSpCas9	negative selection	4385831
201266564	201266586	2	+	27760321	OCIAML2	viability	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.09439409258351317	[746,643]	[427,653]	-1	hSpCas9	negative selection	4469290
201266608	201266630	2	-	27760321	OCIAML2	viability	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.4340261560400016	[79,54]	[46,106]	6	hSpCas9	negative selection	4469291
201266715	201266737	2	+	27760321	OCIAML2	viability	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-0.14438655080412488	[36,14]	[17,18]	-2	hSpCas9	negative selection	4469292
201266775	201266797	2	+	27760321	OCIAML2	viability	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.6320574567322298	[748,586]	[701,1002]	8	hSpCas9	negative selection	4469293
201272626	201272648	2	+	27760321	OCIAML2	viability	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	0.24432215715997402	[429,398]	[335,477]	3	hSpCas9	negative selection	4469294
201266564	201266586	2	+	27760321	MV411	viability	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.6156834567546184	[746,643]	[813,531]	4	hSpCas9	negative selection	4552753
201266608	201266630	2	-	27760321	MV411	viability	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.33172032649086836	[79,54]	[0,85]	-2	hSpCas9	negative selection	4552754
201266715	201266737	2	+	27760321	MV411	viability	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	1.1379407362496137	[36,14]	[0,89]	8	hSpCas9	negative selection	4552755
201266775	201266797	2	+	27760321	MV411	viability	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	1.7024001445892911	[748,586]	[1695,1017]	9	hSpCas9	negative selection	4552756
201272626	201272648	2	+	27760321	MV411	viability	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	-0.09937734600469132	[429,398]	[226,297]	0	hSpCas9	negative selection	4552757
201266564	201266586	2	+	27760321	HL60	viability	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.2707406257180054	[746,643]	[666,700]	3	hSpCas9	negative selection	4636216
201266608	201266630	2	-	27760321	HL60	viability	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-1.3653678104289462	[79,54]	[25,15]	-8	hSpCas9	negative selection	4636217
201266715	201266737	2	+	27760321	HL60	viability	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	1.5421384366424244	[36,14]	[89,27]	9	hSpCas9	negative selection	4636218
201266775	201266797	2	+	27760321	HL60	viability	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.7455563641571102	[748,586]	[967,845]	8	hSpCas9	negative selection	4636219
201272626	201272648	2	+	27760321	HL60	viability	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	-0.21208659793687945	[429,398]	[287,296]	-2	hSpCas9	negative selection	4636220
201266564	201266586	2	+	27760321	HT1080	viability	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.5257836340635824	[643,502]	[274,387]	2	hSpCas9	negative selection	4719679
201266608	201266630	2	-	27760321	HT1080	viability	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.6563207360936145	[54,42]	[9,14]	-3	hSpCas9	negative selection	4719680
201266715	201266737	2	+	27760321	HT1080	viability	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-2.429279739642115	[14,11]	[0,0]	-7	hSpCas9	negative selection	4719681
201266775	201266797	2	+	27760321	HT1080	viability	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	1.80741319075021	[586,457]	[781,669]	8	hSpCas9	negative selection	4719682
201272626	201272648	2	+	27760321	HT1080	viability	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	0.9434351385130322	[398,311]	[290,251]	5	hSpCas9	negative selection	4719683
201266564	201266586	2	+	27760321	HT29	viability after 7 days	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.411962700784839	[643,502]	[1484,842,694]	6	hSpCas9	negative selection	4803142
201266608	201266630	2	-	27760321	HT29	viability after 7 days	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.3559401917321403	[54,42]	[44,83,18]	-5	hSpCas9	negative selection	4803143
201266715	201266737	2	+	27760321	HT29	viability after 7 days	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	0.6197379603308564	[14,11]	[21,48,8]	8	hSpCas9	negative selection	4803144
201266775	201266797	2	+	27760321	HT29	viability after 7 days	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	-0.008116319870964173	[586,457]	[735,775,505]	0	hSpCas9	negative selection	4803145
201272626	201272648	2	+	27760321	HT29	viability after 7 days	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	-0.09087744828745592	[398,311]	[333,463,473]	-1	hSpCas9	negative selection	4803146
201266564	201266586	2	+	27760321	HT29	viability after 25 days	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.48885570325388583	[643,502]	[871,977,909]	5	hSpCas9	negative selection	4886605
201266608	201266630	2	-	27760321	HT29	viability after 25 days	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.4305042133840038	[54,42]	[80,51,94]	5	hSpCas9	negative selection	4886606
201266715	201266737	2	+	27760321	HT29	viability after 25 days	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-0.7019793654440258	[14,11]	[11,0,15]	-5	hSpCas9	negative selection	4886607
201266775	201266797	2	+	27760321	HT29	viability after 25 days	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.23260354013041262	[586,457]	[710,742,642]	2	hSpCas9	negative selection	4886608
201272626	201272648	2	+	27760321	HT29	viability after 25 days	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	0.32331804983653123	[398,311]	[415,512,611]	3	hSpCas9	negative selection	4886609
201266564	201266586	2	+	27760321	HT29	viability after 22 days	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.5983445321211376	[643,502]	[700,1059,1260]	6	hSpCas9	negative selection	4970068
201266608	201266630	2	-	27760321	HT29	viability after 22 days	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	1.2807193959942051	[54,42]	[216,32,160]	9	hSpCas9	negative selection	4970069
201266715	201266737	2	+	27760321	HT29	viability after 22 days	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	1.3616883805442161	[14,11]	[63,0,54]	9	hSpCas9	negative selection	4970070
201266775	201266797	2	+	27760321	HT29	viability after 22 days	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.16783992411805726	[586,457]	[706,632,694]	1	hSpCas9	negative selection	4970071
201272626	201272648	2	+	27760321	HT29	viability after 22 days	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	0.27502800686786455	[398,311]	[589,455,442]	3	hSpCas9	negative selection	4970072
201266564	201266586	2	+	27760321	HT29	viability after 19 days	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.7315758459628419	[643,502]	[995,1146,1112]	7	hSpCas9	negative selection	5053531
201266608	201266630	2	-	27760321	HT29	viability after 19 days	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.4400945320145526	[54,42]	[32,20,67]	-4	hSpCas9	negative selection	5053532
201266715	201266737	2	+	27760321	HT29	viability after 19 days	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-1.164776488378684	[14,11]	[17,0,2]	-7	hSpCas9	negative selection	5053533
201266775	201266797	2	+	27760321	HT29	viability after 19 days	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.42808092134244013	[586,457]	[829,883,703]	4	hSpCas9	negative selection	5053534
201272626	201272648	2	+	27760321	HT29	viability after 19 days	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	-0.41928088780977074	[398,311]	[325,275,311]	-4	hSpCas9	negative selection	5053535
201266564	201266586	2	+	27760321	HT29	viability after 16 days	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.5465529195717502	[643,502]	[918,927,962]	6	hSpCas9	negative selection	5136994
201266608	201266630	2	-	27760321	HT29	viability after 16 days	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.6876022321007129	[54,42]	[36,10,54]	-6	hSpCas9	negative selection	5136995
201266715	201266737	2	+	27760321	HT29	viability after 16 days	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	-0.2744423669970386	[14,11]	[0,28,5]	-3	hSpCas9	negative selection	5136996
201266775	201266797	2	+	27760321	HT29	viability after 16 days	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.4393931732391956	[586,457]	[692,965,704]	5	hSpCas9	negative selection	5136997
201272626	201272648	2	+	27760321	HT29	viability after 16 days	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	0.21438155736623618	[398,311]	[424,499,454]	2	hSpCas9	negative selection	5136998
201266564	201266586	2	+	27760321	HT29	viability after 13 days	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.6316920087903843	[643,502]	[1237,976,885]	7	hSpCas9	negative selection	5220457
201266608	201266630	2	-	27760321	HT29	viability after 13 days	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.6887159911309042	[54,42]	[13,41,48]	-6	hSpCas9	negative selection	5220458
201266715	201266737	2	+	27760321	HT29	viability after 13 days	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	0.8306625603806328	[14,11]	[49,11,21]	9	hSpCas9	negative selection	5220459
201266775	201266797	2	+	27760321	HT29	viability after 13 days	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.18188078002289343	[586,457]	[757,625,678]	2	hSpCas9	negative selection	5220460
201272626	201272648	2	+	27760321	HT29	viability after 13 days	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	-0.12828262519643227	[398,311]	[351,451,330]	-1	hSpCas9	negative selection	5220461
201266564	201266586	2	+	27760321	HT29	viability after 10 days	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.46509092916639583	[643,502]	[858,1100,1007]	6	hSpCas9	negative selection	5303920
201266608	201266630	2	-	27760321	HT29	viability after 10 days	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.10015388322466023	[54,42]	[24,128,44]	1	hSpCas9	negative selection	5303921
201266715	201266737	2	+	27760321	HT29	viability after 10 days	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	1.5462540186305205	[14,11]	[60,25,59]	9	hSpCas9	negative selection	5303922
201266775	201266797	2	+	27760321	HT29	viability after 10 days	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.265894843521596	[586,457]	[810,751,788]	3	hSpCas9	negative selection	5303923
201272626	201272648	2	+	27760321	HT29	viability after 10 days	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	-0.27955399480957394	[398,311]	[429,254,407]	-4	hSpCas9	negative selection	5303924
201266564	201266586	2	+	27760321	MOLM13	viability	CCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	1.3840952287319594	[746,643]	[794,1213]	8	hSpCas9	negative selection	5387383
201266608	201266630	2	-	27760321	MOLM13	viability	AGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	1.0132665531521403	[79,54]	[163,0]	7	hSpCas9	negative selection	5387384
201266715	201266737	2	+	27760321	MOLM13	viability	ACCTACCTAAACACTAGAAAGG	CASP8	ENSG00000064012	3.8368684732891807	[36,14]	[0,374]	9	hSpCas9	negative selection	5387385
201266775	201266797	2	+	27760321	MOLM13	viability	CAAATTTCTGCCTACAGGTGGG	CASP8	ENSG00000064012	0.9352909360519909	[748,586]	[1066,416]	6	hSpCas9	negative selection	5387386
201272626	201272648	2	+	27760321	MOLM13	viability	TCCTCCTCTTAGAACCTGCTGG	CASP8	ENSG00000064012	0.45955736752201715	[429,398]	[211,414]	3	hSpCas9	negative selection	5387387
201233477	201233500	2	+	27661255	K562	viability	GTCTGAGCTGGTCTGAAGGCTGG	CASP8	ENSG00000064012	-0.12920196243438414	[677,780]	[592,478]	-4	dCas9-KRAB	negative selection	5468221
201233565	201233588	2	+	27661255	K562	viability	GCTGCCTGAGGAATACCAGTGGG	CASP8	ENSG00000064012	0.2369556908337904	[563,613]	[578,531]	7	dCas9-KRAB	negative selection	5468222
201233935	201233958	2	+	27661255	K562	viability	GTCAAGACATCAGTAGAAGGAGG	CASP8	ENSG00000064012	0.10033616543706567	[775,937]	[847,631]	3	dCas9-KRAB	negative selection	5468223
201260592	201260615	2	+	27661255	K562	viability	GTGCTACCATCGTGAGAGTAAGG	CASP8	ENSG00000064012	0.06560180745696237	[617,586]	[596,424]	2	dCas9-KRAB	negative selection	5468224
201233521	201233544	2	-	27661255	K562	viability	GCTGTTGGCGGGGTACAGGCAGG	CASP8	ENSG00000064012	0.04396140195607057	[317,334]	[293,246]	1	dCas9-KRAB	negative selection	5468225
201260580	201260603	2	-	27661255	K562	viability	GATGGTAGCACCTTCGTCACAGG	CASP8	ENSG00000064012	0.09103953703515932	[1530,1473]	[1417,1160]	3	dCas9-KRAB	negative selection	5468226
201269571	201269594	2	-	27260156	BXPC3	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.24491081019864636	[568]	[586,699,645,920]	5	hSpCas9	negative selection	5533484
201269584	201269607	2	+	27260156	BXPC3	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.11566934657571754	[583]	[505,681,712,770]	2	hSpCas9	negative selection	5533485
201266564	201266587	2	-	27260156	BXPC3	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.5272141557513315	[138]	[177,194,221,250]	9	hSpCas9	negative selection	5533486
201266681	201266704	2	+	27260156	BXPC3	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.2945650374197222	[129]	[91,114,218,263]	6	hSpCas9	negative selection	5597762
201272736	201272759	2	-	27260156	BXPC3	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.03425823234312453	[240]	[229,289,239,272]	0	hSpCas9	negative selection	5597763
201271596	201271619	2	-	27260156	BXPC3	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.18349636964855343	[1782]	[2185,1853,2083,2367]	4	hSpCas9	negative selection	5597764
201269571	201269594	2	-	27260156	A673	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.27796646215944654	[568]	[857,806,762,891]	6	hSpCas9	negative selection	5654735
201269584	201269607	2	+	27260156	A673	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.199080994160533	[583]	[842,780,756,844]	5	hSpCas9	negative selection	5654736
201266564	201266587	2	-	27260156	A673	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.22681200416463065	[138]	[291,149,149,201]	5	hSpCas9	negative selection	5654737
201266681	201266704	2	+	27260156	A673	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.048316796620542	[129]	[173,166,111,195]	1	hSpCas9	negative selection	5719013
201272736	201272759	2	-	27260156	A673	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.36723393535769877	[240]	[237,197,224,238]	-7	hSpCas9	negative selection	5719014
201271596	201271619	2	-	27260156	A673	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.11255742468518415	[1782]	[2623,2213,2049,2411]	2	hSpCas9	negative selection	5719015
201269571	201269594	2	-	27260156	A375	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.5374145708293312	[568]	[985,1228,1086,629]	7	hSpCas9	negative selection	5775986
201269584	201269607	2	+	27260156	A375	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.394063736362577	[583]	[809,905,936,925]	6	hSpCas9	negative selection	5775987
201266564	201266587	2	-	27260156	A375	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.0770377121083079	[138]	[221,146,220,99]	1	hSpCas9	negative selection	5775988
201266681	201266704	2	+	27260156	A375	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.22789375995911398	[129]	[303,193,150,76]	3	hSpCas9	negative selection	5840264
201272736	201272759	2	-	27260156	A375	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.40962078895830933	[240]	[300,382,557,265]	6	hSpCas9	negative selection	5840265
201271596	201271619	2	-	27260156	A375	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.4177818469867556	[1782]	[2974,3025,2725,2463]	6	hSpCas9	negative selection	5840266
201269571	201269594	2	-	27260156	COLO741	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.28203005157372485	[568]	[884,977,793]	6	hSpCas9	negative selection	5897237
201269584	201269607	2	+	27260156	COLO741	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.09390247080489206	[583]	[1015,711,685]	2	hSpCas9	negative selection	5897238
201266564	201266587	2	-	27260156	COLO741	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.2580007169488783	[138]	[211,300,129]	5	hSpCas9	negative selection	5897239
201266681	201266704	2	+	27260156	COLO741	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.5012202775888335	[129]	[127,83,138]	-8	hSpCas9	negative selection	5961515
201272736	201272759	2	-	27260156	COLO741	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.18831445970692617	[240]	[345,319,158]	-4	hSpCas9	negative selection	5961516
201271596	201271619	2	-	27260156	COLO741	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.23790637915174706	[1782]	[2691,2979,2403]	5	hSpCas9	negative selection	5961517
201269571	201269594	2	-	27260156	CAL120	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.5110484346143077	[568]	[1015,848,1159]	7	hSpCas9	negative selection	6018488
201269584	201269607	2	+	27260156	CAL120	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.5167593956790113	[583]	[1530,804,859]	7	hSpCas9	negative selection	6018489
201266564	201266587	2	-	27260156	CAL120	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.010886478047049675	[138]	[158,160,199]	0	hSpCas9	negative selection	6018490
201266681	201266704	2	+	27260156	CAL120	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.22774314113844096	[129]	[213,228,129]	3	hSpCas9	negative selection	6082766
201272736	201272759	2	-	27260156	CAL120	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.11144084752280459	[240]	[352,322,169]	-2	hSpCas9	negative selection	6082767
201271596	201271619	2	-	27260156	CAL120	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.2994926745177495	[1782]	[2705,2970,2513]	4	hSpCas9	negative selection	6082768
201269571	201269594	2	-	27260156	CADOES1	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.37966276085259876	[568]	[724,735,631,659]	6	hSpCas9	negative selection	6139739
201269584	201269607	2	+	27260156	CADOES1	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.15877377533580667	[583]	[497,591,565,775]	2	hSpCas9	negative selection	6139740
201266564	201266587	2	-	27260156	CADOES1	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.07216897433371972	[138]	[102,134,136,169]	1	hSpCas9	negative selection	6139741
201266681	201266704	2	+	27260156	CADOES1	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.389984963519602	[129]	[202,93,164,171]	6	hSpCas9	negative selection	6204017
201272736	201272759	2	-	27260156	CADOES1	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.059517023146429704	[240]	[193,325,141,197]	-1	hSpCas9	negative selection	6204018
201271596	201271619	2	-	27260156	CADOES1	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.5367117226666105	[1782]	[2557,2112,2352,2604]	8	hSpCas9	negative selection	6204019
201269571	201269594	2	-	27260156	EWS502	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.1364407107938298	[568]	[521,742,621,781]	2	hSpCas9	negative selection	6260990
201269584	201269607	2	+	27260156	EWS502	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	-0.010580715184816403	[583]	[555,401,715,810]	0	hSpCas9	negative selection	6260991
201266564	201266587	2	-	27260156	EWS502	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.5956992305955597	[138]	[191,221,164,319]	8	hSpCas9	negative selection	6260992
201266681	201266704	2	+	27260156	EWS502	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.394465922201759	[129]	[115,134,249,236]	7	hSpCas9	negative selection	6325268
201272736	201272759	2	-	27260156	EWS502	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.2747288899795448	[240]	[204,200,139,303]	-5	hSpCas9	negative selection	6325269
201271596	201271619	2	-	27260156	EWS502	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.3385379352913822	[1782]	[2082,2821,2367,2280]	6	hSpCas9	negative selection	6325270
201269571	201269594	2	-	27260156	EW8	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.43775943449323684	[568]	[521,593,490,899]	7	hSpCas9	negative selection	6382241
201269584	201269607	2	+	27260156	EW8	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.003489741021363124	[583]	[649,531,351,402]	0	hSpCas9	negative selection	6382242
201266564	201266587	2	-	27260156	EW8	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.4507554258665005	[138]	[185,195,119,122]	7	hSpCas9	negative selection	6382243
201266681	201266704	2	+	27260156	EW8	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.31072421422766405	[129]	[162,120,111,132]	5	hSpCas9	negative selection	6446519
201272736	201272759	2	-	27260156	EW8	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.336149490984885	[240]	[130,173,213,86]	-6	hSpCas9	negative selection	6446520
201271596	201271619	2	-	27260156	EW8	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.2816961809422964	[1782]	[1747,1758,1660,1867]	5	hSpCas9	negative selection	6446521
201269571	201269594	2	-	27260156	CORL105	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.5206032009807577	[568]	[952,887,1155,857]	8	hSpCas9	negative selection	6503492
201269584	201269607	2	+	27260156	CORL105	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.12139652453325245	[583]	[524,807,992,678]	2	hSpCas9	negative selection	6503493
201266564	201266587	2	-	27260156	CORL105	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.020022748625624587	[138]	[176,107,231,154]	0	hSpCas9	negative selection	6503494
201266681	201266704	2	+	27260156	CORL105	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.3379839969199565	[129]	[233,156,138,232]	6	hSpCas9	negative selection	6567770
201272736	201272759	2	-	27260156	CORL105	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.8527015998746048	[240]	[88,215,203,119]	-9	hSpCas9	negative selection	6567771
201271596	201271619	2	-	27260156	CORL105	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.37886433154403676	[1782]	[2611,2401,3234,2690]	7	hSpCas9	negative selection	6567772
201269571	201269594	2	-	27260156	HS294T	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.7928085333813767	[568]	[261,556,237,489]	8	hSpCas9	negative selection	6624743
201269584	201269607	2	+	27260156	HS294T	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.3106447882062136	[583]	[166,225,294,476]	4	hSpCas9	negative selection	6624744
201266564	201266587	2	-	27260156	HS294T	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.25319756955198125	[138]	[42,50,57,114]	3	hSpCas9	negative selection	6624745
201266681	201266704	2	+	27260156	HS294T	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.7957589372736957	[129]	[24,12,263,48]	8	hSpCas9	negative selection	6689021
201272736	201272759	2	-	27260156	HS294T	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.25235551911305376	[240]	[61,141,49,53]	-4	hSpCas9	negative selection	6689022
201271596	201271619	2	-	27260156	HS294T	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.45175817165920185	[1782]	[1028,986,656,1113]	6	hSpCas9	negative selection	6689023
201269571	201269594	2	-	27260156	HCC44	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.10247394873205773	[568]	[893,644,547,671]	1	hSpCas9	negative selection	6745994
201269584	201269607	2	+	27260156	HCC44	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.38058082813917143	[583]	[1100,715,879,783]	6	hSpCas9	negative selection	6745995
201266564	201266587	2	-	27260156	HCC44	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.022138763916165427	[138]	[85,113,278,177]	0	hSpCas9	negative selection	6745996
201266681	201266704	2	+	27260156	HCC44	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.1981732910203713	[129]	[327,131,100,121]	3	hSpCas9	negative selection	6810272
201272736	201272759	2	-	27260156	HCC44	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.35808021694941183	[240]	[240,222,700,299]	6	hSpCas9	negative selection	6810273
201271596	201271619	2	-	27260156	HCC44	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.18984001143810358	[1782]	[2600,2051,2591,2057]	3	hSpCas9	negative selection	6810274
201269571	201269594	2	-	27260156	G402	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.4489849905024115	[568]	[1430,636,1138,646]	5	hSpCas9	negative selection	6867245
201269584	201269607	2	+	27260156	G402	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.40509018921272527	[583]	[1231,1272,731,610]	5	hSpCas9	negative selection	6867246
201266564	201266587	2	-	27260156	G402	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.0678862282157493	[138]	[117,288,117,182]	0	hSpCas9	negative selection	6867247
201266681	201266704	2	+	27260156	G402	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.3617632547491798	[129]	[104,192,368,135]	4	hSpCas9	negative selection	6931523
201272736	201272759	2	-	27260156	G402	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.8900327167558375	[240]	[73,216,169,163]	-8	hSpCas9	negative selection	6931524
201271596	201271619	2	-	27260156	G402	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.6435688325474169	[1782]	[3767,4697,2215,3045]	7	hSpCas9	negative selection	6931525
201269571	201269594	2	-	27260156	L33	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.36794750594412373	[568]	[819,272,503,647]	7	hSpCas9	negative selection	6988496
201269584	201269607	2	+	27260156	L33	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.24441343688497325	[583]	[583,318,434,714]	5	hSpCas9	negative selection	6988497
201266564	201266587	2	-	27260156	L33	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.4932088048935299	[138]	[100,93,140,229]	8	hSpCas9	negative selection	6988498
201266681	201266704	2	+	27260156	L33	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.3106745845998009	[129]	[110,40,51,124]	-6	hSpCas9	negative selection	7052774
201272736	201272759	2	-	27260156	L33	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.5374401660280317	[240]	[104,73,98,221]	-8	hSpCas9	negative selection	7052775
201271596	201271619	2	-	27260156	L33	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	-0.14364611887775824	[1782]	[1578,617,1106,1608]	-3	hSpCas9	negative selection	7052776
201269571	201269594	2	-	27260156	K562	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.3481258776669953	[568]	[491,724,886,475]	4	hSpCas9	negative selection	7109747
201269584	201269607	2	+	27260156	K562	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.6494321843569222	[583]	[907,895,762,705]	8	hSpCas9	negative selection	7109748
201266564	201266587	2	-	27260156	K562	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.5191350468256264	[138]	[201,265,123,126]	6	hSpCas9	negative selection	7109749
201266681	201266704	2	+	27260156	K562	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	1.241129612162084	[129]	[155,214,460,247]	9	hSpCas9	negative selection	7174025
201272736	201272759	2	-	27260156	K562	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.03827890308158677	[240]	[133,332,222,189]	0	hSpCas9	negative selection	7174026
201271596	201271619	2	-	27260156	K562	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.18414856422881254	[1782]	[1850,1499,2165,1669]	2	hSpCas9	negative selection	7174027
201269571	201269594	2	-	27260156	HT29	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.24343930205544428	[568]	[894,898,650,834]	5	hSpCas9	negative selection	7230998
201269584	201269607	2	+	27260156	HT29	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.2158804367254578	[583]	[774,774,873,855]	4	hSpCas9	negative selection	7230999
201266564	201266587	2	-	27260156	HT29	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.05445358213398466	[138]	[223,167,156,156]	1	hSpCas9	negative selection	7231000
201266681	201266704	2	+	27260156	HT29	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.7194614613962973	[129]	[92,120,100,72]	-8	hSpCas9	negative selection	7295276
201272736	201272759	2	-	27260156	HT29	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.2863961670266282	[240]	[206,301,213,238]	-5	hSpCas9	negative selection	7295277
201271596	201271619	2	-	27260156	HT29	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.27812639375163606	[1782]	[2718,3118,2426,2316]	5	hSpCas9	negative selection	7295278
201269571	201269594	2	-	27260156	MHHES1	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	-0.10970398996232841	[568]	[643,519,822,416]	-2	hSpCas9	negative selection	7352249
201269584	201269607	2	+	27260156	MHHES1	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.31505793717610736	[583]	[760,797,719,936]	6	hSpCas9	negative selection	7352250
201266564	201266587	2	-	27260156	MHHES1	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	-0.44045317317512667	[138]	[147,120,118,82]	-7	hSpCas9	negative selection	7352251
201266681	201266704	2	+	27260156	MHHES1	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.3950330001347886	[129]	[88,93,95,149]	-6	hSpCas9	negative selection	7416527
201272736	201272759	2	-	27260156	MHHES1	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.02788474472961633	[240]	[168,397,343,205]	0	hSpCas9	negative selection	7416528
201271596	201271619	2	-	27260156	MHHES1	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.30123141293955547	[1782]	[3346,2205,2386,2072]	5	hSpCas9	negative selection	7416529
201269571	201269594	2	-	27260156	MEWO	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.28574666595530196	[568]	[664,603,680]	6	hSpCas9	negative selection	7473500
201269584	201269607	2	+	27260156	MEWO	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.17592323132879056	[583]	[875,549,475]	4	hSpCas9	negative selection	7473501
201266564	201266587	2	-	27260156	MEWO	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	-0.1136353806930459	[138]	[143,153,66]	-2	hSpCas9	negative selection	7473502
201266681	201266704	2	+	27260156	MEWO	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.07103718902887346	[129]	[253,68,84]	1	hSpCas9	negative selection	7537778
201272736	201272759	2	-	27260156	MEWO	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	0.03138256736438605	[240]	[238,208,244]	0	hSpCas9	negative selection	7537779
201271596	201271619	2	-	27260156	MEWO	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.00507081387686914	[1782]	[1959,1669,1446]	0	hSpCas9	negative selection	7537780
201269571	201269594	2	-	27260156	LNCAPCLONEFGC	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.6967771522609377	[568]	[744,939,1090,597]	9	hSpCas9	negative selection	7594751
201269584	201269607	2	+	27260156	LNCAPCLONEFGC	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.1046273109932247	[583]	[535,467,715,583]	1	hSpCas9	negative selection	7594752
201266564	201266587	2	-	27260156	LNCAPCLONEFGC	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.5832052482462822	[138]	[166,109,349,156]	8	hSpCas9	negative selection	7594753
201266681	201266704	2	+	27260156	LNCAPCLONEFGC	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.021096901930573564	[129]	[63,135,123,140]	0	hSpCas9	negative selection	7659029
201272736	201272759	2	-	27260156	LNCAPCLONEFGC	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.2657068459502898	[240]	[161,135,237,201]	-4	hSpCas9	negative selection	7659030
201271596	201271619	2	-	27260156	LNCAPCLONEFGC	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.4574598903559175	[1782]	[2263,1784,2484,2402]	7	hSpCas9	negative selection	7659031
201269571	201269594	2	-	27260156	PANC0327	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.5969906391927646	[568]	[790,685,718,873]	8	hSpCas9	negative selection	7716002
201269584	201269607	2	+	27260156	PANC0327	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.35346397934938817	[583]	[704,619,678,655]	5	hSpCas9	negative selection	7716003
201266564	201266587	2	-	27260156	PANC0327	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.279526053030434	[138]	[246,106,160,97]	4	hSpCas9	negative selection	7716004
201266681	201266704	2	+	27260156	PANC0327	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.664659077725468	[129]	[88,61,29,112]	-7	hSpCas9	negative selection	7780280
201272736	201272759	2	-	27260156	PANC0327	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.03718977447013172	[240]	[343,111,183,217]	0	hSpCas9	negative selection	7780281
201271596	201271619	2	-	27260156	PANC0327	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.48787122649934567	[1782]	[2299,2166,2046,2382]	7	hSpCas9	negative selection	7780282
201269571	201269594	2	-	27260156	NCIH2009	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.2741962397609007	[568]	[1065,1027,807]	4	hSpCas9	negative selection	7837253
201269584	201269607	2	+	27260156	NCIH2009	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.4258921880034869	[583]	[1127,756,1413]	6	hSpCas9	negative selection	7837254
201266564	201266587	2	-	27260156	NCIH2009	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.39995154549731704	[138]	[388,175,230]	5	hSpCas9	negative selection	7837255
201266681	201266704	2	+	27260156	NCIH2009	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.5739677501851357	[129]	[126,111,127]	-6	hSpCas9	negative selection	7901531
201272736	201272759	2	-	27260156	NCIH2009	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.21088551038025516	[240]	[251,267,344]	-3	hSpCas9	negative selection	7901532
201271596	201271619	2	-	27260156	NCIH2009	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.2708761125750634	[1782]	[3513,2692,2910]	4	hSpCas9	negative selection	7901533
201269571	201269594	2	-	27260156	NCIH1373	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.5804446720002464	[568]	[1049,1037,985,190]	6	hSpCas9	negative selection	7958504
201269584	201269607	2	+	27260156	NCIH1373	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.25926524656655	[583]	[1013,844,657,166]	2	hSpCas9	negative selection	7958505
201266564	201266587	2	-	27260156	NCIH1373	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.28111182685336056	[138]	[123,98,251,74]	2	hSpCas9	negative selection	7958506
201266681	201266704	2	+	27260156	NCIH1373	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.3703452182826459	[129]	[183,61,99,31]	-4	hSpCas9	negative selection	8022782
201272736	201272759	2	-	27260156	NCIH1373	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.41190881473247876	[240]	[264,69,222,73]	-4	hSpCas9	negative selection	8022783
201271596	201271619	2	-	27260156	NCIH1373	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.6800475917608853	[1782]	[4451,3045,2812,700]	6	hSpCas9	negative selection	8022784
201269571	201269594	2	-	27260156	PATU8902	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.24170683906924084	[568]	[1174,786,867,922]	2	hSpCas9	negative selection	8079755
201269584	201269607	2	+	27260156	PATU8902	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.08906258065486533	[583]	[1366,242,999,790]	0	hSpCas9	negative selection	8079756
201266564	201266587	2	-	27260156	PATU8902	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.6025404875618252	[138]	[392,586,78,152]	6	hSpCas9	negative selection	8079757
201266681	201266704	2	+	27260156	PATU8902	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.3531458437024997	[129]	[342,108,152,350]	3	hSpCas9	negative selection	8144033
201272736	201272759	2	-	27260156	PATU8902	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-1.517682244915371	[240]	[35,65,204,141]	-8	hSpCas9	negative selection	8144034
201271596	201271619	2	-	27260156	PATU8902	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.8570882278562784	[1782]	[3332,4398,4545,5840]	8	hSpCas9	negative selection	8144035
201269571	201269594	2	-	27260156	PANC1	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.37853534581242143	[568]	[616,853,655,475]	6	hSpCas9	negative selection	8201006
201269584	201269607	2	+	27260156	PANC1	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.4354879572868227	[583]	[566,761,820,587]	7	hSpCas9	negative selection	8201007
201266564	201266587	2	-	27260156	PANC1	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.22051549369713586	[138]	[87,182,184,112]	3	hSpCas9	negative selection	8201008
201266681	201266704	2	+	27260156	PANC1	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.17861533694214327	[129]	[67,140,178,120]	3	hSpCas9	negative selection	8265284
201272736	201272759	2	-	27260156	PANC1	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.3038101731285592	[240]	[122,115,324,105]	-5	hSpCas9	negative selection	8265285
201271596	201271619	2	-	27260156	PANC1	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.4191859811287366	[1782]	[2173,2655,2007,1527]	6	hSpCas9	negative selection	8265286
201269571	201269594	2	-	27260156	PANC0813	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.21267715367256113	[568]	[1109,658,754,612]	3	hSpCas9	negative selection	8322257
201269584	201269607	2	+	27260156	PANC0813	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.06324893574452933	[583]	[745,713,685,721]	1	hSpCas9	negative selection	8322258
201266564	201266587	2	-	27260156	PANC0813	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.19489312360265276	[138]	[330,189,121,120]	3	hSpCas9	negative selection	8322259
201266681	201266704	2	+	27260156	PANC0813	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.19612093219427673	[129]	[63,229,144,89]	-3	hSpCas9	negative selection	8386535
201272736	201272759	2	-	27260156	PANC0813	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.3722947012623088	[240]	[251,136,135,344]	-5	hSpCas9	negative selection	8386536
201271596	201271619	2	-	27260156	PANC0813	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.38463011982436157	[1782]	[3079,2178,2886,2814]	6	hSpCas9	negative selection	8386537
201269571	201269594	2	-	27260156	RDES	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.19649715369545095	[568]	[734,608,763,907]	3	hSpCas9	negative selection	8443508
201269584	201269607	2	+	27260156	RDES	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.21187459723768848	[583]	[619,775,659,1112]	3	hSpCas9	negative selection	8443509
201266564	201266587	2	-	27260156	RDES	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.6749887021437844	[138]	[281,162,290,284]	9	hSpCas9	negative selection	8443510
201266681	201266704	2	+	27260156	RDES	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.06131882513053055	[129]	[166,167,146,127]	1	hSpCas9	negative selection	8507786
201272736	201272759	2	-	27260156	RDES	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.41243026680815986	[240]	[162,200,167,320]	-6	hSpCas9	negative selection	8507787
201271596	201271619	2	-	27260156	RDES	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.43579037352098293	[1782]	[2217,2703,2714,3628]	7	hSpCas9	negative selection	8507788
201269571	201269594	2	-	27260156	PC3	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.48114841733494773	[568]	[440,877,1366,782]	8	hSpCas9	negative selection	8564759
201269584	201269607	2	+	27260156	PC3	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.3308372061347851	[583]	[473,722,1103,815]	7	hSpCas9	negative selection	8564760
201266564	201266587	2	-	27260156	PC3	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.4561956385182213	[138]	[191,148,190,201]	8	hSpCas9	negative selection	8564761
201266681	201266704	2	+	27260156	PC3	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.3181208719528108	[129]	[133,127,154,222]	6	hSpCas9	negative selection	8629037
201272736	201272759	2	-	27260156	PC3	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.16348524135554254	[240]	[177,142,365,223]	-4	hSpCas9	negative selection	8629038
201271596	201271619	2	-	27260156	PC3	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.11863545996444413	[1782]	[1555,1650,3098,1806]	2	hSpCas9	negative selection	8629039
201269571	201269594	2	-	27260156	PATU8988T	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.5981203303459581	[568]	[784,826,910,801]	8	hSpCas9	negative selection	8686010
201269584	201269607	2	+	27260156	PATU8988T	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.21185045654244544	[583]	[626,712,578,705]	3	hSpCas9	negative selection	8686011
201266564	201266587	2	-	27260156	PATU8988T	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.4416319904956254	[138]	[154,152,158,266]	7	hSpCas9	negative selection	8686012
201266681	201266704	2	+	27260156	PATU8988T	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-1.212635037749713	[129]	[41,38,79,53]	-9	hSpCas9	negative selection	8750288
201272736	201272759	2	-	27260156	PATU8988T	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.6688477698477824	[240]	[147,72,123,241]	-8	hSpCas9	negative selection	8750289
201271596	201271619	2	-	27260156	PATU8988T	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.25652523112597825	[1782]	[2190,1984,2025,2020]	4	hSpCas9	negative selection	8750290
201269571	201269594	2	-	27260156	T47D	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.4089018190724355	[568]	[841,869,866,943]	8	hSpCas9	negative selection	8807261
201269584	201269607	2	+	27260156	T47D	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.39700926115654583	[583]	[931,883,785,986]	8	hSpCas9	negative selection	8807262
201266564	201266587	2	-	27260156	T47D	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.39291509159646276	[138]	[207,216,212,211]	8	hSpCas9	negative selection	8807263
201266681	201266704	2	+	27260156	T47D	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.11206952892598787	[129]	[167,185,118,180]	2	hSpCas9	negative selection	8871539
201272736	201272759	2	-	27260156	T47D	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.4273898941120948	[240]	[249,185,221,177]	-7	hSpCas9	negative selection	8871540
201271596	201271619	2	-	27260156	T47D	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.23635300912719304	[1782]	[2525,2078,2524,2695]	5	hSpCas9	negative selection	8871541
201269571	201269594	2	-	27260156	SU8686	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.12280489454886329	[568]	[421,518,790,787]	2	hSpCas9	negative selection	8928512
201269584	201269607	2	+	27260156	SU8686	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.44945876883421226	[583]	[582,743,892,1003]	7	hSpCas9	negative selection	8928513
201266564	201266587	2	-	27260156	SU8686	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.4166654516771777	[138]	[208,168,196,153]	7	hSpCas9	negative selection	8928514
201266681	201266704	2	+	27260156	SU8686	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.19374307753439335	[129]	[163,82,94,103]	-3	hSpCas9	negative selection	8992790
201272736	201272759	2	-	27260156	SU8686	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.41200846100789934	[240]	[125,149,171,297]	-6	hSpCas9	negative selection	8992791
201271596	201271619	2	-	27260156	SU8686	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.13640852496876832	[1782]	[1692,1723,2085,2387]	2	hSpCas9	negative selection	8992792
201269571	201269594	2	-	27260156	SKES1	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.2958749078354893	[568]	[600,857,695,637]	6	hSpCas9	negative selection	9049763
201269584	201269607	2	+	27260156	SKES1	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.2376672229715477	[583]	[646,709,855,539]	5	hSpCas9	negative selection	9049764
201266564	201266587	2	-	27260156	SKES1	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.279438883317606	[138]	[279,202,147,71]	6	hSpCas9	negative selection	9049765
201266681	201266704	2	+	27260156	SKES1	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.21271474065282603	[129]	[120,167,72,94]	-5	hSpCas9	negative selection	9114041
201272736	201272759	2	-	27260156	SKES1	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.44643105078000445	[240]	[276,264,67,125]	-7	hSpCas9	negative selection	9114042
201271596	201271619	2	-	27260156	SKES1	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.10443201304525429	[1782]	[2142,1918,1856,1760]	2	hSpCas9	negative selection	9114043
201269571	201269594	2	-	27260156	TOV112D	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.2505784602103973	[568]	[387,798,627,894]	5	hSpCas9	negative selection	9171014
201269584	201269607	2	+	27260156	TOV112D	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.352576693530037	[583]	[470,924,910,700]	6	hSpCas9	negative selection	9171015
201266564	201266587	2	-	27260156	TOV112D	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.6355937343377391	[138]	[299,321,137,139]	9	hSpCas9	negative selection	9171016
201266681	201266704	2	+	27260156	TOV112D	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.03412554148062785	[129]	[178,78,112,151]	0	hSpCas9	negative selection	9235292
201272736	201272759	2	-	27260156	TOV112D	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.14374454044277996	[240]	[243,209,286,134]	-3	hSpCas9	negative selection	9235293
201271596	201271619	2	-	27260156	TOV112D	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.027364311108198924	[1782]	[1812,2217,1588,1755]	0	hSpCas9	negative selection	9235294
201269571	201269594	2	-	27260156	TC71	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.3784858165799495	[568]	[834,930,610,799]	8	hSpCas9	negative selection	9292265
201269584	201269607	2	+	27260156	TC71	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.2443826167433057	[583]	[816,631,727,790]	6	hSpCas9	negative selection	9292266
201266564	201266587	2	-	27260156	TC71	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.09068891531509382	[138]	[172,183,115,162]	2	hSpCas9	negative selection	9292267
201266681	201266704	2	+	27260156	TC71	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	0.08448421945691531	[129]	[92,177,146,175]	2	hSpCas9	negative selection	9356543
201272736	201272759	2	-	27260156	TC71	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.4329809487782277	[240]	[193,171,165,236]	-8	hSpCas9	negative selection	9356544
201271596	201271619	2	-	27260156	TC71	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.14442561478102967	[1782]	[1846,2038,2185,2398]	3	hSpCas9	negative selection	9356545
201269571	201269594	2	-	27260156	TC32	viability	TGATCGACCCTCCGCCAGAAAGG	CASP8	ENSG00000064012	0.10931902010904854	[568]	[654,404,643,637]	2	hSpCas9	negative selection	9413516
201269584	201269607	2	+	27260156	TC32	viability	GGGTCGATCATCTATTAATAAGG	CASP8	ENSG00000064012	0.06752719822877584	[583]	[580,511,686,522]	1	hSpCas9	negative selection	9413517
201266564	201266587	2	-	27260156	TC32	viability	TCCTTTGCGGAATGTAGTCCAGG	CASP8	ENSG00000064012	0.27276023184812703	[138]	[122,192,188,108]	5	hSpCas9	negative selection	9413518
201266681	201266704	2	+	27260156	TC32	viability	GCTCTTCCGAATTAATAGACTGG	CASP8	ENSG00000064012	-0.01383879266037713	[129]	[101,80,185,137]	0	hSpCas9	negative selection	9477794
201272736	201272759	2	-	27260156	TC32	viability	AGTCGTTGATTATCTTCAGCAGG	CASP8	ENSG00000064012	-0.8976212927487268	[240]	[77,74,181,181]	-9	hSpCas9	negative selection	9477795
201271596	201271619	2	-	27260156	TC32	viability	GTCATCATCCAGTTTGCATTTGG	CASP8	ENSG00000064012	0.34741337062715116	[1782]	[2010,1608,2734,2375]	6	hSpCas9	negative selection	9477796
201258310	201258333	2	-	27869803	HPAFII	viability after 27 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.53396543383998	[157]	[26,197,NaN]	4	hSpCas9	negative selection	9572959
201266563	201266586	2	+	27869803	HPAFII	viability after 27 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.22966700467264622	[514]	[147,299,NaN]	-2	hSpCas9	negative selection	9572960
201269563	201269586	2	+	27869803	HPAFII	viability after 27 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.11270759785396844	[306]	[163,136,NaN]	-1	hSpCas9	negative selection	9572961
201274917	201274940	2	+	27869803	HPAFII	viability after 27 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.5510393188000304	[724]	[624,502,NaN]	4	hSpCas9	negative selection	9572962
201276924	201276947	2	+	27869803	HPAFII	viability after 27 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.20365347277633244	[246]	[172,129,NaN]	1	hSpCas9	negative selection	9572963
201285121	201285144	2	-	27869803	HPAFII	viability after 27 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.29551162509322015	[124]	[52,53,NaN]	-2	hSpCas9	negative selection	9572964
201258310	201258333	2	-	27869803	HPAFII	viability after 15 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.3855811533538058	[157]	[227,217,NaN]	4	hSpCas9	negative selection	9655408
201266563	201266586	2	+	27869803	HPAFII	viability after 15 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.010524649546498122	[514]	[509,573,NaN]	0	hSpCas9	negative selection	9655409
201269563	201269586	2	+	27869803	HPAFII	viability after 15 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	-0.006071292457563049	[306]	[396,285,NaN]	0	hSpCas9	negative selection	9655410
201274917	201274940	2	+	27869803	HPAFII	viability after 15 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.07959978361401565	[724]	[1291,531,NaN]	0	hSpCas9	negative selection	9655411
201276924	201276947	2	+	27869803	HPAFII	viability after 15 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.07490091422081535	[246]	[323,251,NaN]	0	hSpCas9	negative selection	9655412
201285121	201285144	2	-	27869803	HPAFII	viability after 15 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.02432208114283041	[124]	[83,161,NaN]	0	hSpCas9	negative selection	9655413
201258310	201258333	2	-	27869803	ASPC1	viability after 36 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.6163017522613853	[313]	[15,211,237]	6	hSpCas9	negative selection	9737857
201266563	201266586	2	+	27869803	ASPC1	viability after 36 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.5954180503131928	[1383]	[341,549,117]	-5	hSpCas9	negative selection	9737858
201269563	201269586	2	+	27869803	ASPC1	viability after 36 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	0.8263583823687333	[1084]	[1293,450,402]	7	hSpCas9	negative selection	9737859
201274917	201274940	2	+	27869803	ASPC1	viability after 36 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.39366383122219206	[1371]	[928,893,201]	4	hSpCas9	negative selection	9737860
201276924	201276947	2	+	27869803	ASPC1	viability after 36 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	-0.22540664855525974	[712]	[183,77,337]	-2	hSpCas9	negative selection	9737861
201285121	201285144	2	-	27869803	ASPC1	viability after 36 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	0.50046882342911	[418]	[305,181,154]	5	hSpCas9	negative selection	9737862
201258310	201258333	2	-	27869803	PATU8988S	viability after 35 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	-0.817144882021363	[391]	[135,42,NaN]	-7	hSpCas9	negative selection	9820306
201266563	201266586	2	+	27869803	PATU8988S	viability after 35 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.32865660013143705	[873]	[468,414,NaN]	4	hSpCas9	negative selection	9820307
201269563	201269586	2	+	27869803	PATU8988S	viability after 35 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	0.2375762830997845	[814]	[386,386,NaN]	2	hSpCas9	negative selection	9820308
201274917	201274940	2	+	27869803	PATU8988S	viability after 35 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.2375715806513492	[1301]	[507,728,NaN]	2	hSpCas9	negative selection	9820309
201276924	201276947	2	+	27869803	PATU8988S	viability after 35 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.6817414539276976	[507]	[410,244,NaN]	7	hSpCas9	negative selection	9820310
201285121	201285144	2	-	27869803	PATU8988S	viability after 35 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.8796874413100113	[433]	[93,95,NaN]	-7	hSpCas9	negative selection	9820311
201258310	201258333	2	-	27869803	PATU8988S	viability after 31 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	-0.9685654121383637	[391]	[56,108,NaN]	-7	hSpCas9	negative selection	9902755
201266563	201266586	2	+	27869803	PATU8988S	viability after 31 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.5156035846348146	[873]	[378,649,NaN]	6	hSpCas9	negative selection	9902756
201269563	201269586	2	+	27869803	PATU8988S	viability after 31 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	0.35835667027502904	[814]	[453,368,NaN]	4	hSpCas9	negative selection	9902757
201274917	201274940	2	+	27869803	PATU8988S	viability after 31 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.02055071567963873	[1301]	[391,697,NaN]	0	hSpCas9	negative selection	9902758
201276924	201276947	2	+	27869803	PATU8988S	viability after 31 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.47524420572507275	[507]	[241,331,NaN]	6	hSpCas9	negative selection	9902759
201285121	201285144	2	-	27869803	PATU8988S	viability after 31 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.9298440858519259	[433]	[85,96,NaN]	-7	hSpCas9	negative selection	9902760
201258310	201258333	2	-	27869803	HPAFII	viability after 35 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	1.02111155699168	[157]	[0,343,NaN]	7	hSpCas9	negative selection	9985204
201266563	201266586	2	+	27869803	HPAFII	viability after 35 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.10631967313816282	[514]	[179,393,NaN]	0	hSpCas9	negative selection	9985205
201269563	201269586	2	+	27869803	HPAFII	viability after 35 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	0.1640837725572719	[306]	[215,126,NaN]	1	hSpCas9	negative selection	9985206
201274917	201274940	2	+	27869803	HPAFII	viability after 35 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.6928414677858801	[724]	[581,605,NaN]	4	hSpCas9	negative selection	9985207
201276924	201276947	2	+	27869803	HPAFII	viability after 35 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.1411296690213359	[246]	[159,112,NaN]	0	hSpCas9	negative selection	9985208
201285121	201285144	2	-	27869803	HPAFII	viability after 35 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.8742624905794671	[124]	[18,51,NaN]	-5	hSpCas9	negative selection	9985209
201258310	201258333	2	-	27869803	HPAFII	viability after 31 days	CCTAACTCCACGTGCTCAGCAGG	CASP8	ENSG00000064012	0.7373717732379294	[157]	[9,297,NaN]	5	hSpCas9	negative selection	10067653
201266563	201266586	2	+	27869803	HPAFII	viability after 31 days	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.20165714475826801	[514]	[206,468,NaN]	1	hSpCas9	negative selection	10067654
201269563	201269586	2	+	27869803	HPAFII	viability after 31 days	AGTCTGTACCTTTCTGGCGGAGG	CASP8	ENSG00000064012	0.4068756557278061	[306]	[237,217,NaN]	3	hSpCas9	negative selection	10067655
201274917	201274940	2	+	27869803	HPAFII	viability after 31 days	CTCGGACTCTCCAAGAGAACAGG	CASP8	ENSG00000064012	0.6260727154352093	[724]	[615,640,NaN]	4	hSpCas9	negative selection	10067656
201276924	201276947	2	+	27869803	HPAFII	viability after 31 days	AACTTCACAGCATTAGGGACAGG	CASP8	ENSG00000064012	0.5608602154623492	[246]	[192,216,NaN]	4	hSpCas9	negative selection	10067657
201285121	201285144	2	-	27869803	HPAFII	viability after 31 days	TCCTCTGAATCAGTCTCAACAGG	CASP8	ENSG00000064012	-0.10561302564311426	[124]	[24,108,NaN]	0	hSpCas9	negative selection	10067658
201266665	201266688	2	-	28162770	P31FUJ	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	1.1473405044182794	[67]	[176]	9	hSpCas9	negative selection	10126245
201272662	201272685	2	+	28162770	P31FUJ	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.16326127116130174	[80]	[84]	-1	hSpCas9	negative selection	10126246
201266750	201266773	2	+	28162770	P31FUJ	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.6285608201281336	[190]	[346]	7	hSpCas9	negative selection	10126247
201276845	201276868	2	+	28162770	P31FUJ	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	1.1457094188393513	[94]	[246]	9	hSpCas9	negative selection	10126248
201266545	201266568	2	-	28162770	P31FUJ	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.9760118104215287	[182]	[422]	9	hSpCas9	negative selection	10126249
201266563	201266586	2	+	28162770	P31FUJ	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.9129689353191568	[173]	[384]	9	hSpCas9	negative selection	10126250
201276860	201276883	2	-	28162770	P31FUJ	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	-0.15734997598491318	[148]	[156]	-1	hSpCas9	negative selection	10126251
201266582	201266605	2	+	28162770	P31FUJ	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.8478162557939058	[347]	[735]	8	hSpCas9	negative selection	10126252
201266608	201266631	2	-	28162770	P31FUJ	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.3893932025057528	[101]	[156]	4	hSpCas9	negative selection	10126253
201266717	201266740	2	+	28162770	P31FUJ	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	0.5205578280024961	[34]	[58]	6	hSpCas9	negative selection	10126254
201266665	201266688	2	-	28162770	TF1	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10295611
201272662	201272685	2	+	28162770	TF1	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10295612
201266750	201266773	2	+	28162770	TF1	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10295613
201276845	201276868	2	+	28162770	TF1	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10295614
201266545	201266568	2	-	28162770	TF1	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10295615
201266563	201266586	2	+	28162770	TF1	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10295616
201276860	201276883	2	-	28162770	TF1	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10295617
201266582	201266605	2	+	28162770	TF1	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	NaN	[NaN]	[761]	1	hSpCas9	negative selection	10295618
201266608	201266631	2	-	28162770	TF1	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	NaN	[NaN]	[137]	1	hSpCas9	negative selection	10295619
201266717	201266740	2	+	28162770	TF1	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10295620
201266665	201266688	2	-	28162770	SKM1	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	0.12737222890802635	[28]	[55]	1	hSpCas9	negative selection	10464977
201272662	201272685	2	+	28162770	SKM1	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	0.2175266661646318	[17]	[36]	2	hSpCas9	negative selection	10464978
201266750	201266773	2	+	28162770	SKM1	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.951112899617166	[66]	[228]	8	hSpCas9	negative selection	10464979
201276845	201276868	2	+	28162770	SKM1	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	-0.8220016980220055	[19]	[19]	-6	hSpCas9	negative selection	10464980
201266545	201266568	2	-	28162770	SKM1	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.28818121972841737	[62]	[135]	3	hSpCas9	negative selection	10464981
201266563	201266586	2	+	28162770	SKM1	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.36242287311542204	[43]	[99]	3	hSpCas9	negative selection	10464982
201276860	201276883	2	-	28162770	SKM1	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.8320024471288023	[33]	[106]	7	hSpCas9	negative selection	10464983
201266582	201266605	2	+	28162770	SKM1	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.8409633147004238	[101]	[322]	7	hSpCas9	negative selection	10464984
201266608	201266631	2	-	28162770	SKM1	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.6569424517515091	[32]	[36]	-5	hSpCas9	negative selection	10464985
201266717	201266740	2	+	28162770	SKM1	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	1.7846558737984697	[10]	[66]	9	hSpCas9	negative selection	10464986
201266665	201266688	2	-	28162770	SKM1	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	0.12737222890802635	[28]	[55]	1	hSpCas9	negative selection	10634343
201272662	201272685	2	+	28162770	SKM1	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	0.2175266661646318	[17]	[36]	2	hSpCas9	negative selection	10634344
201266750	201266773	2	+	28162770	SKM1	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.951112899617166	[66]	[228]	8	hSpCas9	negative selection	10634345
201276845	201276868	2	+	28162770	SKM1	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	-0.8220016980220055	[19]	[19]	-6	hSpCas9	negative selection	10634346
201266545	201266568	2	-	28162770	SKM1	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.28818121972841737	[62]	[135]	3	hSpCas9	negative selection	10634347
201266563	201266586	2	+	28162770	SKM1	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.36242287311542204	[43]	[99]	3	hSpCas9	negative selection	10634348
201276860	201276883	2	-	28162770	SKM1	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.8320024471288023	[33]	[106]	7	hSpCas9	negative selection	10634349
201266582	201266605	2	+	28162770	SKM1	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.8409633147004238	[101]	[322]	7	hSpCas9	negative selection	10634350
201266608	201266631	2	-	28162770	SKM1	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.6569424517515091	[32]	[36]	-5	hSpCas9	negative selection	10634351
201266717	201266740	2	+	28162770	SKM1	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	1.7846558737984697	[10]	[66]	9	hSpCas9	negative selection	10634352
201266665	201266688	2	-	28162770	PL21	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	1.438299351684085	[77]	[91]	9	hSpCas9	negative selection	10803709
201272662	201272685	2	+	28162770	PL21	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.12178848039804246	[69]	[27]	-1	hSpCas9	negative selection	10803710
201266750	201266773	2	+	28162770	PL21	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.25592739267506703	[278]	[144]	2	hSpCas9	negative selection	10803711
201276845	201276868	2	+	28162770	PL21	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	0.3229963622748536	[89]	[48]	3	hSpCas9	negative selection	10803712
201266545	201266568	2	-	28162770	PL21	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.30799560424998784	[218]	[117]	2	hSpCas9	negative selection	10803713
201266563	201266586	2	+	28162770	PL21	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.15600419573595514	[127]	[49]	-1	hSpCas9	negative selection	10803714
201276860	201276883	2	-	28162770	PL21	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.10060394093840563	[104]	[48]	0	hSpCas9	negative selection	10803715
201266582	201266605	2	+	28162770	PL21	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.6465412846774993	[272]	[185]	5	hSpCas9	negative selection	10803716
201266608	201266631	2	-	28162770	PL21	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-1.2737915738430923	[99]	[17]	-7	hSpCas9	negative selection	10803717
201266717	201266740	2	+	28162770	PL21	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	-0.8587540745642483	[24]	[5]	-5	hSpCas9	negative selection	10803718
201266665	201266688	2	-	28162770	P31FUJ	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	1.1473405044182794	[67]	[176]	9	hSpCas9	negative selection	10973075
201272662	201272685	2	+	28162770	P31FUJ	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.16326127116130174	[80]	[84]	-1	hSpCas9	negative selection	10973076
201266750	201266773	2	+	28162770	P31FUJ	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.6285608201281336	[190]	[346]	7	hSpCas9	negative selection	10973077
201276845	201276868	2	+	28162770	P31FUJ	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	1.1457094188393513	[94]	[246]	9	hSpCas9	negative selection	10973078
201266545	201266568	2	-	28162770	P31FUJ	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.9760118104215287	[182]	[422]	9	hSpCas9	negative selection	10973079
201266563	201266586	2	+	28162770	P31FUJ	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.9129689353191568	[173]	[384]	9	hSpCas9	negative selection	10973080
201276860	201276883	2	-	28162770	P31FUJ	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	-0.15734997598491318	[148]	[156]	-1	hSpCas9	negative selection	10973081
201266582	201266605	2	+	28162770	P31FUJ	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.8478162557939058	[347]	[735]	8	hSpCas9	negative selection	10973082
201266608	201266631	2	-	28162770	P31FUJ	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.3893932025057528	[101]	[156]	4	hSpCas9	negative selection	10973083
201266717	201266740	2	+	28162770	P31FUJ	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	0.5205578280024961	[34]	[58]	6	hSpCas9	negative selection	10973084
201266665	201266688	2	-	28162770	OCIAML5	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	-0.05929918502943898	[70]	[122]	0	hSpCas9	negative selection	11142441
201272662	201272685	2	+	28162770	OCIAML5	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	0.36474481820915106	[36]	[85]	3	hSpCas9	negative selection	11142442
201266750	201266773	2	+	28162770	OCIAML5	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.5176900491139805	[88]	[229]	4	hSpCas9	negative selection	11142443
201276845	201276868	2	+	28162770	OCIAML5	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	-0.1431153528673874	[51]	[84]	-1	hSpCas9	negative selection	11142444
201266545	201266568	2	-	28162770	OCIAML5	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.22235827026255772	[169]	[357]	1	hSpCas9	negative selection	11142445
201266563	201266586	2	+	28162770	OCIAML5	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.9427430978744936	[65]	[228]	7	hSpCas9	negative selection	11142446
201276860	201276883	2	-	28162770	OCIAML5	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	-1.2963686646480355	[82]	[60]	-6	hSpCas9	negative selection	11142447
201266582	201266605	2	+	28162770	OCIAML5	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.4875998012635685	[193]	[490]	4	hSpCas9	negative selection	11142448
201266608	201266631	2	-	28162770	OCIAML5	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.827413528641449	[63]	[204]	7	hSpCas9	negative selection	11142449
201266717	201266740	2	+	28162770	OCIAML5	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	-0.1475224543901681	[26]	[43]	-1	hSpCas9	negative selection	11142450
201266665	201266688	2	-	28162770	EOL1	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	0.31109671388968263	[178]	[116]	3	hSpCas9	negative selection	11311807
201272662	201272685	2	+	28162770	EOL1	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.09071898508277587	[94]	[46]	0	hSpCas9	negative selection	11311808
201266750	201266773	2	+	28162770	EOL1	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.5896806209756742	[419]	[332]	5	hSpCas9	negative selection	11311809
201276845	201276868	2	+	28162770	EOL1	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	1.1398157584736008	[173]	[201]	8	hSpCas9	negative selection	11311810
201266545	201266568	2	-	28162770	EOL1	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	-0.26487340549757504	[446]	[195]	-2	hSpCas9	negative selection	11311811
201266563	201266586	2	+	28162770	EOL1	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.15990255022877695	[298]	[140]	-1	hSpCas9	negative selection	11311812
201276860	201276883	2	-	28162770	EOL1	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.8790331123181658	[160]	[155]	7	hSpCas9	negative selection	11311813
201266582	201266605	2	+	28162770	EOL1	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.41815432322348833	[401]	[282]	4	hSpCas9	negative selection	11311814
201266608	201266631	2	-	28162770	EOL1	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.7853850238989092	[86]	[78]	7	hSpCas9	negative selection	11311815
201266717	201266740	2	+	28162770	EOL1	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	0.13605187676424624	[18]	[10]	1	hSpCas9	negative selection	11311816
201266665	201266688	2	-	28162770	MOLM13	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	0.2155022199102935	[161]	[135]	1	hSpCas9	negative selection	11481173
201272662	201272685	2	+	28162770	MOLM13	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-1.4125290027027486	[80]	[21]	-6	hSpCas9	negative selection	11481174
201266750	201266773	2	+	28162770	MOLM13	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.05725706138573605	[435]	[327]	0	hSpCas9	negative selection	11481175
201276845	201276868	2	+	28162770	MOLM13	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	0.42631027779317954	[175]	[170]	3	hSpCas9	negative selection	11481176
201266545	201266568	2	-	28162770	MOLM13	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	1.0666247318874673	[277]	[420]	7	hSpCas9	negative selection	11481177
201266563	201266586	2	+	28162770	MOLM13	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	0.45140125875600984	[263]	[260]	3	hSpCas9	negative selection	11481178
201276860	201276883	2	-	28162770	MOLM13	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	1.337220429778405	[178]	[326]	8	hSpCas9	negative selection	11481179
201266582	201266605	2	+	28162770	MOLM13	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.8132533530166114	[402]	[511]	6	hSpCas9	negative selection	11481180
201266608	201266631	2	-	28162770	MOLM13	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.4914686339580753	[209]	[107]	-3	hSpCas9	negative selection	11481181
201266717	201266740	2	+	28162770	MOLM13	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	-0.026875310204999003	[30]	[21]	0	hSpCas9	negative selection	11481182
201266665	201266688	2	-	28162770	HEL	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	0.3083197929297977	[144]	[114]	2	hSpCas9	negative selection	11650539
201272662	201272685	2	+	28162770	HEL	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	0.7605753222942151	[46]	[50]	6	hSpCas9	negative selection	11650540
201266750	201266773	2	+	28162770	HEL	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.17325354869913678	[341]	[246]	1	hSpCas9	negative selection	11650541
201276845	201276868	2	+	28162770	HEL	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	0.4486517798840544	[142]	[124]	4	hSpCas9	negative selection	11650542
201266545	201266568	2	-	28162770	HEL	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.8663648532759154	[333]	[389]	7	hSpCas9	negative selection	11650543
201266563	201266586	2	+	28162770	HEL	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.06775455080465811	[233]	[142]	0	hSpCas9	negative selection	11650544
201276860	201276883	2	-	28162770	HEL	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.3797044261665632	[137]	[114]	3	hSpCas9	negative selection	11650545
201266582	201266605	2	+	28162770	HEL	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.7060414139088748	[378]	[395]	6	hSpCas9	negative selection	11650546
201266608	201266631	2	-	28162770	HEL	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.43920278153581926	[162]	[76]	-3	hSpCas9	negative selection	11650547
201266717	201266740	2	+	28162770	HEL	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	-0.880823124056656	[22]	[7]	-5	hSpCas9	negative selection	11650548
201266665	201266688	2	-	28162770	MV411	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	0.06583074429282754	[92]	[81]	0	hSpCas9	negative selection	11819905
201272662	201272685	2	+	28162770	MV411	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.3164633344105514	[33]	[22]	-2	hSpCas9	negative selection	11819906
201266750	201266773	2	+	28162770	MV411	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.20896340296813978	[189]	[184]	1	hSpCas9	negative selection	11819907
201276845	201276868	2	+	28162770	MV411	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	-1.833482444600792	[109]	[25]	-8	hSpCas9	negative selection	11819908
201266545	201266568	2	-	28162770	MV411	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.16787029346445712	[204]	[193]	1	hSpCas9	negative selection	11819909
201266563	201266586	2	+	28162770	MV411	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.6536474231445373	[154]	[82]	-5	hSpCas9	negative selection	11819910
201276860	201276883	2	-	28162770	MV411	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.23264054885469487	[97]	[96]	2	hSpCas9	negative selection	11819911
201266582	201266605	2	+	28162770	MV411	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.4981936268381326	[294]	[350]	4	hSpCas9	negative selection	11819912
201266608	201266631	2	-	28162770	MV411	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.16304536349240284	[87]	[82]	1	hSpCas9	negative selection	11819913
201266717	201266740	2	+	28162770	MV411	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	-1.0155968550510188	[23]	[9]	-6	hSpCas9	negative selection	11819914
201266665	201266688	2	-	28162770	MONOMAC1	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	-0.47575287512561726	[73]	[60]	-4	hSpCas9	negative selection	11989271
201272662	201272685	2	+	28162770	MONOMAC1	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	0.6856062023022873	[31]	[58]	6	hSpCas9	negative selection	11989272
201266750	201266773	2	+	28162770	MONOMAC1	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.10814798399323233	[207]	[256]	1	hSpCas9	negative selection	11989273
201276845	201276868	2	+	28162770	MONOMAC1	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	2.8412912715995455	[64]	[533]	9	hSpCas9	negative selection	11989274
201266545	201266568	2	-	28162770	MONOMAC1	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.12489124782780847	[167]	[209]	1	hSpCas9	negative selection	11989275
201266563	201266586	2	+	28162770	MONOMAC1	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.07674261334184174	[91]	[99]	0	hSpCas9	negative selection	11989276
201276860	201276883	2	-	28162770	MONOMAC1	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.36292164753170814	[96]	[142]	3	hSpCas9	negative selection	11989277
201266582	201266605	2	+	28162770	MONOMAC1	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	-0.4147903735924811	[206]	[177]	-4	hSpCas9	negative selection	11989278
201266608	201266631	2	-	28162770	MONOMAC1	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	0.6711732803849051	[62]	[114]	6	hSpCas9	negative selection	11989279
201266717	201266740	2	+	28162770	MONOMAC1	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	-0.366961848501866	[17]	[15]	-3	hSpCas9	negative selection	11989280
201266665	201266688	2	-	28162770	OCIAML2	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	-0.405338364990442	[26]	[112]	-3	hSpCas9	negative selection	12158637
201272662	201272685	2	+	28162770	OCIAML2	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	-0.0971714297147166	[10]	[56]	-1	hSpCas9	negative selection	12158638
201266750	201266773	2	+	28162770	OCIAML2	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.1504664615327081	[45]	[282]	1	hSpCas9	negative selection	12158639
201276845	201276868	2	+	28162770	OCIAML2	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	-0.12580132824472007	[24]	[126]	-1	hSpCas9	negative selection	12158640
201266545	201266568	2	-	28162770	OCIAML2	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	0.3141472488402331	[45]	[316]	3	hSpCas9	negative selection	12158641
201266563	201266586	2	+	28162770	OCIAML2	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.2742326124386577	[35]	[164]	-2	hSpCas9	negative selection	12158642
201276860	201276883	2	-	28162770	OCIAML2	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	-0.06123888910445929	[15]	[84]	0	hSpCas9	negative selection	12158643
201266582	201266605	2	+	28162770	OCIAML2	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.35111618912106457	[56]	[402]	3	hSpCas9	negative selection	12158644
201266608	201266631	2	-	28162770	OCIAML2	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.6018743585204137	[22]	[83]	-4	hSpCas9	negative selection	12158645
201266717	201266740	2	+	28162770	OCIAML2	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	2.483566485144714	[0]	[30]	9	hSpCas9	negative selection	12158646
201266665	201266688	2	-	28162770	OCIAML3	viability	GAAGAGCAGCTCCTTCAGGAAGG	CASP8	ENSG00000064012	-0.7094848577440993	[25]	[47]	-5	hSpCas9	negative selection	12328003
201272662	201272685	2	+	28162770	OCIAML3	viability	ATGGAGAAGAGGGTCATCCTGGG	CASP8	ENSG00000064012	0.4334730960979438	[12]	[52]	4	hSpCas9	negative selection	12328004
201266750	201266773	2	+	28162770	OCIAML3	viability	GGAACTTCAGACACCAGGCAGGG	CASP8	ENSG00000064012	0.4205406682449921	[73]	[298]	4	hSpCas9	negative selection	12328005
201276845	201276868	2	+	28162770	OCIAML3	viability	CAAATGAAAAGCAAACCTCGGGG	CASP8	ENSG00000064012	-0.13944177685868187	[26]	[73]	-1	hSpCas9	negative selection	12328006
201266545	201266568	2	-	28162770	OCIAML3	viability	CAGGCTCAGGAACTTGAGGGAGG	CASP8	ENSG00000064012	1.0700735775145958	[67]	[430]	8	hSpCas9	negative selection	12328007
201266563	201266586	2	+	28162770	OCIAML3	viability	GCCTGGACTACATTCCGCAAAGG	CASP8	ENSG00000064012	-0.06676063745929445	[50]	[146]	0	hSpCas9	negative selection	12328008
201276860	201276883	2	-	28162770	OCIAML3	viability	ATGATCAGACAGTATCCCCGAGG	CASP8	ENSG00000064012	0.8978454560055115	[23]	[134]	7	hSpCas9	negative selection	12328009
201266582	201266605	2	+	28162770	OCIAML3	viability	AAGGAAGCAAGAACCCATCAAGG	CASP8	ENSG00000064012	0.11321061044799097	[97]	[319]	1	hSpCas9	negative selection	12328010
201266608	201266631	2	-	28162770	OCIAML3	viability	GAGTCTCTGGAATAACATCAAGG	CASP8	ENSG00000064012	-0.6913048416790784	[22]	[42]	-5	hSpCas9	negative selection	12328011
201266717	201266740	2	+	28162770	OCIAML3	viability	CTACCTAAACACTAGAAAGGAGG	CASP8	ENSG00000064012	-1.8164000616606115	[6]	[5]	-8	hSpCas9	negative selection	12328012