Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:842
• Symbol:CASP9
• Description:caspase 9

DataSource: http://genomecrispr.dkfz.de/#!/results/CASP9

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
15506971	15506994	1	+	26472758	Jiyoye	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.22826403118738603	[462]	[408]	1	hSpCas9	negative selection	23809
15506916	15506939	1	-	26472758	Jiyoye	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.06015630565568042	[144]	[113]	0	hSpCas9	negative selection	23810
15506036	15506059	1	-	26472758	Jiyoye	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-1.3177173803597575	[237]	[71]	-7	hSpCas9	negative selection	23811
15518140	15518163	1	-	26472758	Jiyoye	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	0.039443597005386355	[39]	[30]	0	hSpCas9	negative selection	23812
15518124	15518147	1	-	26472758	Jiyoye	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	1.314065977114392	[23]	[44]	7	hSpCas9	negative selection	23813
15506898	15506921	1	-	26472758	Jiyoye	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.7492110498418105	[227]	[288]	5	hSpCas9	negative selection	23814
15504648	15504671	1	-	26472758	Jiyoye	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-1.6771409044276018	[228]	[53]	-8	hSpCas9	negative selection	23815
15495426	15495449	1	-	26472758	Jiyoye	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.6229865890043791	[144]	[70]	-4	hSpCas9	negative selection	23816
15495352	15495375	1	+	26472758	Jiyoye	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	2.4071753815058727	[0]	[3]	9	hSpCas9	negative selection	23817
15507024	15507047	1	+	26472758	Jiyoye	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.45744858798709687	[281]	[291]	3	hSpCas9	negative selection	23818
15506971	15506994	1	+	26472758	KBM7	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.030074761605372924	[1772,1561]	[916,693]	0	hSpCas9	negative selection	214927
15506916	15506939	1	-	26472758	KBM7	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.27663045410851317	[868,833]	[668,322]	3	hSpCas9	negative selection	214928
15506036	15506059	1	-	26472758	KBM7	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-0.7990602968482	[735,599]	[150,204]	-6	hSpCas9	negative selection	214929
15518140	15518163	1	-	26472758	KBM7	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	0.8626736060785363	[89,58]	[106,22]	8	hSpCas9	negative selection	214930
15518124	15518147	1	-	26472758	KBM7	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	1.0445227482842998	[134,195]	[214,118]	9	hSpCas9	negative selection	214931
15506898	15506921	1	-	26472758	KBM7	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.5477124384055081	[1068,859]	[728,595]	6	hSpCas9	negative selection	214932
15504648	15504671	1	-	26472758	KBM7	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	0.12496953551372292	[589,282]	[181,247]	1	hSpCas9	negative selection	214933
15495426	15495449	1	-	26472758	KBM7	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	0.45235637633157877	[297,147]	[200,83]	5	hSpCas9	negative selection	214934
15495352	15495375	1	+	26472758	KBM7	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	0.2167422691340204	[13,71]	[1,45]	2	hSpCas9	negative selection	214935
15507024	15507047	1	+	26472758	KBM7	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.38979532819612417	[1541,1634]	[1320,686]	4	hSpCas9	negative selection	214936
15506971	15506994	1	+	26472758	Raji	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.04344922961950082	[668]	[159]	0	hSpCas9	negative selection	406045
15506916	15506939	1	-	26472758	Raji	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	-0.67397617815106	[274]	[39]	-5	hSpCas9	negative selection	406046
15506036	15506059	1	-	26472758	Raji	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-0.026099470100652666	[214]	[48]	0	hSpCas9	negative selection	406047
15518140	15518163	1	-	26472758	Raji	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	1.1073835353735997	[25]	[12]	8	hSpCas9	negative selection	406048
15518124	15518147	1	-	26472758	Raji	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	-0.11178498508856216	[148]	[31]	-1	hSpCas9	negative selection	406049
15506898	15506921	1	-	26472758	Raji	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.8435027258541091	[340]	[141]	7	hSpCas9	negative selection	406050
15504648	15504671	1	-	26472758	Raji	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-1.9297057833616205	[393]	[23]	-8	hSpCas9	negative selection	406051
15495426	15495449	1	-	26472758	Raji	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	0.630061757840413	[141]	[50]	6	hSpCas9	negative selection	406052
15495352	15495375	1	+	26472758	Raji	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	1.0369942074822016	[20]	[9]	8	hSpCas9	negative selection	406053
15507024	15507047	1	+	26472758	Raji	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.12214688804534024	[874]	[220]	1	hSpCas9	negative selection	406054
15506971	15506994	1	+	26472758	K562	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.4355440884034585	[1305]	[1490]	3	hSpCas9	negative selection	597163
15506916	15506939	1	-	26472758	K562	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.4316344639018336	[598]	[681]	3	hSpCas9	negative selection	597164
15506036	15506059	1	-	26472758	K562	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-0.7946508370121455	[523]	[254]	-5	hSpCas9	negative selection	597165
15518140	15518163	1	-	26472758	K562	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	0.24441872766644668	[33]	[33]	1	hSpCas9	negative selection	597166
15518124	15518147	1	-	26472758	K562	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	1.0877905488375923	[242]	[435]	8	hSpCas9	negative selection	597167
15506898	15506921	1	-	26472758	K562	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.6435297676381535	[796]	[1050]	5	hSpCas9	negative selection	597168
15504648	15504671	1	-	26472758	K562	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-1.3405437730547094	[563]	[187]	-6	hSpCas9	negative selection	597169
15495426	15495449	1	-	26472758	K562	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	0.34550485278076126	[247]	[265]	2	hSpCas9	negative selection	597170
15495352	15495375	1	+	26472758	K562	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	0.022026306329999024	[27]	[23]	0	hSpCas9	negative selection	597171
15507024	15507047	1	+	26472758	K562	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.6151715311555412	[1132]	[1464]	5	hSpCas9	negative selection	597172
15493882	15493905	1	+	26627737	DLD1	viability	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.16721345923685704	[464]	[140,228,127]	1	hSpCas9	negative selection	766723
15495420	15495443	1	+	26627737	DLD1	viability	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-1.0090706568154677	[337]	[37,25,86]	-7	hSpCas9	negative selection	766724
15504688	15504711	1	+	26627737	DLD1	viability	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-1.5259078290043173	[539]	[73,64,39]	-8	hSpCas9	negative selection	766742
15507031	15507054	1	+	26627737	DLD1	viability	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-2.136925993828008	[200]	[9,0,28]	-9	hSpCas9	negative selection	766748
15518124	15518147	1	+	26627737	DLD1	viability	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-0.5742361741949215	[639]	[106,154,140]	-5	hSpCas9	negative selection	766760
15524188	15524211	1	-	26627737	DLD1	viability	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.014752702229046344	[668]	[210,229,195]	0	hSpCas9	negative selection	766761
15493882	15493905	1	+	26627737	GBM cells	viability after 5 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.2505259940228958	[278]	[183,171]	4	hSpCas9	negative selection	849038
15495420	15495443	1	+	26627737	GBM cells	viability after 5 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	0.009787092370880934	[337]	[216,147]	0	hSpCas9	negative selection	849039
15504688	15504711	1	+	26627737	GBM cells	viability after 5 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.4202636089856422	[392]	[153,160]	-6	hSpCas9	negative selection	849057
15507031	15507054	1	+	26627737	GBM cells	viability after 5 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.5095509704696719	[72]	[21,32]	-7	hSpCas9	negative selection	849063
15518124	15518147	1	+	26627737	GBM cells	viability after 5 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.017233842074446698	[233]	[129,123]	0	hSpCas9	negative selection	849075
15524188	15524211	1	-	26627737	GBM cells	viability after 5 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.4108129134171185	[323]	[216,244]	6	hSpCas9	negative selection	849076
15493882	15493905	1	+	26627737	GBM cells	viability after 13 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.2267256300962298	[278]	[180,173]	3	hSpCas9	negative selection	931353
15495420	15495443	1	+	26627737	GBM cells	viability after 13 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	0.1162482170541781	[337]	[243,161]	1	hSpCas9	negative selection	931354
15504688	15504711	1	+	26627737	GBM cells	viability after 13 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.14344064471489704	[392]	[229,162]	-2	hSpCas9	negative selection	931372
15507031	15507054	1	+	26627737	GBM cells	viability after 13 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.6407142812762883	[72]	[4,41]	-6	hSpCas9	negative selection	931378
15518124	15518147	1	+	26627737	GBM cells	viability after 13 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-0.07203085451744981	[233]	[165,83]	-1	hSpCas9	negative selection	931390
15524188	15524211	1	-	26627737	GBM cells	viability after 13 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.45487833187360543	[323]	[294,196]	6	hSpCas9	negative selection	931391
15493882	15493905	1	+	26627737	GBM cells	viability after 21 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.04110312385896253	[278]	[156,154]	0	hSpCas9	negative selection	1013668
15495420	15495443	1	+	26627737	GBM cells	viability after 21 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.11588301091932673	[337]	[193,146]	-1	hSpCas9	negative selection	1013669
15504688	15504711	1	+	26627737	GBM cells	viability after 21 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.433255877070286	[392]	[166,149]	-4	hSpCas9	negative selection	1013687
15507031	15507054	1	+	26627737	GBM cells	viability after 21 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	0.7174546371832806	[72]	[71,58]	7	hSpCas9	negative selection	1013693
15518124	15518147	1	+	26627737	GBM cells	viability after 21 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.5259187570846253	[233]	[181,183]	5	hSpCas9	negative selection	1013705
15524188	15524211	1	-	26627737	GBM cells	viability after 21 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.5529147254575673	[323]	[287,230]	5	hSpCas9	negative selection	1013706
15493882	15493905	1	+	26627737	RPE1	viability after 9 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.7958371261861282	[920]	[176,151]	-5	hSpCas9	negative selection	1095983
15495420	15495443	1	+	26627737	RPE1	viability after 9 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.8256319740396733	[1256]	[118,354]	-5	hSpCas9	negative selection	1095984
15504688	15504711	1	+	26627737	RPE1	viability after 9 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.0527824829786224	[707]	[214,211]	0	hSpCas9	negative selection	1096002
15507031	15507054	1	+	26627737	RPE1	viability after 9 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	1.1958292947939708	[73]	[25,87]	7	hSpCas9	negative selection	1096008
15518124	15518147	1	+	26627737	RPE1	viability after 9 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.3178929302460684	[795]	[345,264]	2	hSpCas9	negative selection	1096020
15524188	15524211	1	-	26627737	RPE1	viability after 9 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.5081840521851049	[1041]	[193,274]	-4	hSpCas9	negative selection	1096021
15493882	15493905	1	+	26627737	RPE1	viability after 12 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.02749110181334416	[920]	[251,232]	0	hSpCas9	negative selection	1178298
15495420	15495443	1	+	26627737	RPE1	viability after 12 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.6797309391230719	[1256]	[102,324]	-5	hSpCas9	negative selection	1178299
15504688	15504711	1	+	26627737	RPE1	viability after 12 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.013401471917359048	[707]	[220,153]	0	hSpCas9	negative selection	1178317
15507031	15507054	1	+	26627737	RPE1	viability after 12 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.30563385882054916	[73]	[1,30]	-2	hSpCas9	negative selection	1178323
15518124	15518147	1	+	26627737	RPE1	viability after 12 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.12897047554603816	[795]	[296,166]	0	hSpCas9	negative selection	1178335
15524188	15524211	1	-	26627737	RPE1	viability after 12 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.5794909880263092	[1041]	[164,210]	-4	hSpCas9	negative selection	1178336
15493882	15493905	1	+	26627737	RPE1	viability after 15 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.08211743929880544	[920]	[98,387]	0	hSpCas9	negative selection	1260613
15495420	15495443	1	+	26627737	RPE1	viability after 15 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.9461008436864955	[1256]	[96,268]	-5	hSpCas9	negative selection	1260614
15504688	15504711	1	+	26627737	RPE1	viability after 15 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	0.1371934003615082	[707]	[261,179]	0	hSpCas9	negative selection	1260632
15507031	15507054	1	+	26627737	RPE1	viability after 15 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	1.4040624448307697	[73]	[32,76]	7	hSpCas9	negative selection	1260638
15518124	15518147	1	+	26627737	RPE1	viability after 15 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-0.6308082214548053	[795]	[149,140]	-4	hSpCas9	negative selection	1260650
15524188	15524211	1	-	26627737	RPE1	viability after 15 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.7244152241676285	[1041]	[183,172]	-4	hSpCas9	negative selection	1260651
15493882	15493905	1	+	26627737	RPE1	viability after 18 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.40316397256990316	[920]	[171,204]	-3	hSpCas9	negative selection	1342928
15495420	15495443	1	+	26627737	RPE1	viability after 18 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.606397051729842	[1256]	[129,321]	-4	hSpCas9	negative selection	1342929
15504688	15504711	1	+	26627737	RPE1	viability after 18 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	0.003495352714817601	[707]	[206,174]	0	hSpCas9	negative selection	1342947
15507031	15507054	1	+	26627737	RPE1	viability after 18 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	0.4226400790357876	[73]	[19,33]	2	hSpCas9	negative selection	1342953
15518124	15518147	1	+	26627737	RPE1	viability after 18 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.27746122092594117	[795]	[343,170]	1	hSpCas9	negative selection	1342965
15524188	15524211	1	-	26627737	RPE1	viability after 18 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.541527096318411	[1041]	[198,186]	-3	hSpCas9	negative selection	1342966
15493882	15493905	1	+	26627737	HeLa	viability after 8 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.36947752243485765	[342]	[303,136,163]	3	hSpCas9	negative selection	1425243
15495420	15495443	1	+	26627737	HeLa	viability after 8 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	0.6610651433433693	[395]	[356,235,244]	5	hSpCas9	negative selection	1425244
15504688	15504711	1	+	26627737	HeLa	viability after 8 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	0.4151089610332144	[312]	[202,171,174]	4	hSpCas9	negative selection	1425262
15507031	15507054	1	+	26627737	HeLa	viability after 8 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	0.8517779646348747	[103]	[129,63,62]	7	hSpCas9	negative selection	1425268
15518124	15518147	1	+	26627737	HeLa	viability after 8 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	1.1540544901973748	[141]	[168,135,115]	8	hSpCas9	negative selection	1425280
15524188	15524211	1	-	26627737	HeLa	viability after 8 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.2579442170350078	[674]	[308,257,187]	-2	hSpCas9	negative selection	1425281
15493882	15493905	1	+	26627737	HeLa	viability after 12 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.08212359194157846	[342]	[160,163,123]	0	hSpCas9	negative selection	1507558
15495420	15495443	1	+	26627737	HeLa	viability after 12 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	0.06899167599537823	[395]	[234,56,236]	0	hSpCas9	negative selection	1507559
15504688	15504711	1	+	26627737	HeLa	viability after 12 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	0.33125043031824136	[312]	[207,129,154]	3	hSpCas9	negative selection	1507577
15507031	15507054	1	+	26627737	HeLa	viability after 12 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-1.193813597370503	[103]	[6,18,29]	-8	hSpCas9	negative selection	1507583
15518124	15518147	1	+	26627737	HeLa	viability after 12 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	1.8056009470830143	[141]	[79,306,213]	9	hSpCas9	negative selection	1507595
15524188	15524211	1	-	26627737	HeLa	viability after 12 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.27574928450032443	[674]	[285,200,208]	-2	hSpCas9	negative selection	1507596
15493882	15493905	1	+	26627737	HeLa	viability after 15 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.515799028885183	[342]	[110,93,86]	-4	hSpCas9	negative selection	1589873
15495420	15495443	1	+	26627737	HeLa	viability after 15 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	0.07098823259344109	[395]	[161,129,219]	0	hSpCas9	negative selection	1589874
15504688	15504711	1	+	26627737	HeLa	viability after 15 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.21399092772442407	[312]	[68,79,186]	-2	hSpCas9	negative selection	1589892
15507031	15507054	1	+	26627737	HeLa	viability after 15 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-1.74666926354103	[103]	[20,0,15]	-9	hSpCas9	negative selection	1589898
15518124	15518147	1	+	26627737	HeLa	viability after 15 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	1.38526667038381	[141]	[186,72,195]	8	hSpCas9	negative selection	1589910
15524188	15524211	1	-	26627737	HeLa	viability after 15 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.08112485520812474	[674]	[335,270,163]	0	hSpCas9	negative selection	1589911
15493882	15493905	1	+	26627737	HeLa	viability after 18 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.5383391889518943	[342]	[72,75,86]	-5	hSpCas9	negative selection	1672188
15495420	15495443	1	+	26627737	HeLa	viability after 18 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	0.11833034486851204	[395]	[120,105,219]	1	hSpCas9	negative selection	1672189
15504688	15504711	1	+	26627737	HeLa	viability after 18 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.17858218673731707	[312]	[50,66,186]	-1	hSpCas9	negative selection	1672207
15507031	15507054	1	+	26627737	HeLa	viability after 18 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-1.8037945323423836	[103]	[12,0,15]	-9	hSpCas9	negative selection	1672213
15518124	15518147	1	+	26627737	HeLa	viability after 18 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	1.3851308311691988	[141]	[128,55,195]	8	hSpCas9	negative selection	1672225
15524188	15524211	1	-	26627737	HeLa	viability after 18 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.0032110103812684754	[674]	[248,229,163]	0	hSpCas9	negative selection	1672226
15493882	15493905	1	+	26627737	HCT116	viability after 6 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.9935917146649553	[624]	[107,16]	-5	hSpCas9	negative selection	1754503
15495420	15495443	1	+	26627737	HCT116	viability after 6 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	0.34704473489983256	[1022]	[181,216]	2	hSpCas9	negative selection	1754504
15504688	15504711	1	+	26627737	HCT116	viability after 6 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	2.01014039403964	[605]	[94,542]	8	hSpCas9	negative selection	1754522
15507031	15507054	1	+	26627737	HCT116	viability after 6 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.13809466487003696	[27]	[3,3]	0	hSpCas9	negative selection	1754528
15518124	15518147	1	+	26627737	HCT116	viability after 6 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-1.2431655766164167	[624]	[65,27]	-6	hSpCas9	negative selection	1754540
15524188	15524211	1	-	26627737	HCT116	viability after 6 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.5267030199267353	[562]	[287,38]	3	hSpCas9	negative selection	1754541
15493882	15493905	1	+	26627737	HCT116	viability after 8 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.16469349449304793	[344]	[118,228,159]	-2	hSpCas9	negative selection	1836818
15495420	15495443	1	+	26627737	HCT116	viability after 8 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.17357120651650154	[419]	[218,204,191]	-2	hSpCas9	negative selection	1836819
15504688	15504711	1	+	26627737	HCT116	viability after 8 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.7964202104895272	[354]	[128,163,45]	-7	hSpCas9	negative selection	1836837
15507031	15507054	1	+	26627737	HCT116	viability after 8 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.9751891878627197	[78]	[8,18,37]	-8	hSpCas9	negative selection	1836843
15518124	15518147	1	+	26627737	HCT116	viability after 8 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	1.2827876628050818	[107]	[121,168,142]	9	hSpCas9	negative selection	1836855
15524188	15524211	1	-	26627737	HCT116	viability after 8 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.15180828481022313	[457]	[292,189,199]	-2	hSpCas9	negative selection	1836856
15493882	15493905	1	+	26627737	HCT116	viability after 9 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.4679007308658253	[624]	[222,236]	3	hSpCas9	negative selection	1919133
15495420	15495443	1	+	26627737	HCT116	viability after 9 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-1.069933665211782	[1022]	[190,81]	-6	hSpCas9	negative selection	1919134
15504688	15504711	1	+	26627737	HCT116	viability after 9 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	0.1958645272393484	[605]	[224,153]	1	hSpCas9	negative selection	1919152
15507031	15507054	1	+	26627737	HCT116	viability after 9 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	1.9461732464260901	[27]	[1,49]	9	hSpCas9	negative selection	1919158
15518124	15518147	1	+	26627737	HCT116	viability after 9 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.5037155294959894	[624]	[368,131]	3	hSpCas9	negative selection	1919170
15524188	15524211	1	-	26627737	HCT116	viability after 9 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-2.2495729346747	[562]	[20,39]	-9	hSpCas9	negative selection	1919171
15493882	15493905	1	+	26627737	HCT116	viability after 12 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.6818380309929998	[344]	[81,162,97]	-6	hSpCas9	negative selection	2001448
15495420	15495443	1	+	26627737	HCT116	viability after 12 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.4835666285817958	[419]	[173,150,146]	-5	hSpCas9	negative selection	2001449
15504688	15504711	1	+	26627737	HCT116	viability after 12 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.5581447317809781	[354]	[131,181,66]	-6	hSpCas9	negative selection	2001467
15507031	15507054	1	+	26627737	HCT116	viability after 12 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-1.1841196364429967	[78]	[7,29,17]	-8	hSpCas9	negative selection	2001473
15518124	15518147	1	+	26627737	HCT116	viability after 12 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.8771792706804924	[107]	[132,94,81]	7	hSpCas9	negative selection	2001485
15524188	15524211	1	-	26627737	HCT116	viability after 12 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.2652549056732819	[457]	[202,313,358]	2	hSpCas9	negative selection	2001486
15493882	15493905	1	+	26627737	HCT116	viability after 15 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.9096868670211016	[344]	[121,56,138]	-7	hSpCas9	negative selection	2083763
15495420	15495443	1	+	26627737	HCT116	viability after 15 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.3809646803104141	[419]	[307,108,153]	-4	hSpCas9	negative selection	2083764
15504688	15504711	1	+	26627737	HCT116	viability after 15 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.2292637644451929	[354]	[262,128,140]	-2	hSpCas9	negative selection	2083782
15507031	15507054	1	+	26627737	HCT116	viability after 15 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-1.6991880728645723	[78]	[29,10,2]	-9	hSpCas9	negative selection	2083788
15518124	15518147	1	+	26627737	HCT116	viability after 15 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.9155741336197796	[107]	[127,162,61]	7	hSpCas9	negative selection	2083800
15524188	15524211	1	-	26627737	HCT116	viability after 15 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.14970812383137588	[457]	[370,304,209]	1	hSpCas9	negative selection	2083801
15493882	15493905	1	+	26627737	HCT116	viability after 18 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.700494163444025	[344]	[277,217,322]	6	hSpCas9	negative selection	2166078
15495420	15495443	1	+	26627737	HCT116	viability after 18 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.40957530366608325	[419]	[132,148,177]	-4	hSpCas9	negative selection	2166079
15504688	15504711	1	+	26627737	HCT116	viability after 18 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.26299540450459874	[354]	[237,78,114]	-2	hSpCas9	negative selection	2166097
15507031	15507054	1	+	26627737	HCT116	viability after 18 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.42451714595956624	[78]	[29,30,23]	-4	hSpCas9	negative selection	2166103
15518124	15518147	1	+	26627737	HCT116	viability after 18 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.9450844625095984	[107]	[134,116,45]	7	hSpCas9	negative selection	2166115
15524188	15524211	1	-	26627737	HCT116	viability after 18 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.1914263568366219	[457]	[265,268,220]	1	hSpCas9	negative selection	2166116
15507887	15507910	1	-	24336569	HL60	viability	AGGTGCTCTTGAGAGTTTGAGGG	CASP9	ENSG00000132906	0.4868196589456296	[376]	[1117]	4	hSpCas9	negative selection	2254526
15518109	15518132	1	-	24336569	HL60	viability	TCTGGAGGATTTGGTGATGTCGG	CASP9	ENSG00000132906	-0.8639871697065648	[1511]	[1757]	-7	hSpCas9	negative selection	2254527
15518118	15518141	1	-	24336569	HL60	viability	GACATTGGTTCTGGAGGATTTGG	CASP9	ENSG00000132906	0.35671119037015997	[316]	[858]	3	hSpCas9	negative selection	2254528
15518124	15518147	1	-	24336569	HL60	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	0.053608596866276614	[269]	[592]	0	hSpCas9	negative selection	2254529
15518129	15518152	1	+	24336569	HL60	viability	AGAACCAATGTCCACTGGTCTGG	CASP9	ENSG00000132906	0.8826540220357779	[803]	[3136]	7	hSpCas9	negative selection	2254530
15518139	15518162	1	+	24336569	HL60	viability	TCCACTGGTCTGGGTGTTTCCGG	CASP9	ENSG00000132906	1.595729273019941	[153]	[984]	9	hSpCas9	negative selection	2254531
15518154	15518177	1	+	24336569	HL60	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	-0.4792870445555406	[360]	[547]	-4	hSpCas9	negative selection	2254532
15518169	15518192	1	+	24336569	HL60	viability	ACCTCTGGTTTGCGAATCTCTGG	CASP9	ENSG00000132906	0.5305286060614083	[281]	[861]	5	hSpCas9	negative selection	2254533
15518184	15518207	1	+	24336569	HL60	viability	ATCTCTGGTCTGAGCACCACTGG	CASP9	ENSG00000132906	0.05627721693085497	[1102]	[2426]	0	hSpCas9	negative selection	2254534
15518249	15518272	1	-	24336569	HL60	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	-1.1790748972553187	[213]	[199]	-8	hSpCas9	negative selection	2254535
15507887	15507910	1	-	24336569	KBM7	viability	AGGTGCTCTTGAGAGTTTGAGGG	CASP9	ENSG00000132906	0.30788274123471304	[464]	[1569]	3	hSpCas9	negative selection	2321703
15518109	15518132	1	-	24336569	KBM7	viability	TCTGGAGGATTTGGTGATGTCGG	CASP9	ENSG00000132906	-0.37852377983438235	[978]	[2053]	-3	hSpCas9	negative selection	2321704
15518118	15518141	1	-	24336569	KBM7	viability	GACATTGGTTCTGGAGGATTTGG	CASP9	ENSG00000132906	0.36514223525853684	[344]	[1211]	3	hSpCas9	negative selection	2321705
15518124	15518147	1	-	24336569	KBM7	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	1.4343650419294052	[104]	[773]	9	hSpCas9	negative selection	2321706
15518129	15518152	1	+	24336569	KBM7	viability	AGAACCAATGTCCACTGGTCTGG	CASP9	ENSG00000132906	0.10618868256867975	[934]	[2744]	1	hSpCas9	negative selection	2321707
15518139	15518162	1	+	24336569	KBM7	viability	TCCACTGGTCTGGGTGTTTCCGG	CASP9	ENSG00000132906	-0.7848944004032086	[270]	[428]	-6	hSpCas9	negative selection	2321708
15518154	15518177	1	+	24336569	KBM7	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.1852118292628887	[177]	[551]	1	hSpCas9	negative selection	2321709
15518169	15518192	1	+	24336569	KBM7	viability	ACCTCTGGTTTGCGAATCTCTGG	CASP9	ENSG00000132906	0.7336611181212639	[126]	[575]	6	hSpCas9	negative selection	2321710
15518184	15518207	1	+	24336569	KBM7	viability	ATCTCTGGTCTGAGCACCACTGG	CASP9	ENSG00000132906	0.3588959439746645	[702]	[2458]	3	hSpCas9	negative selection	2321711
15518249	15518272	1	-	24336569	KBM7	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	-0.12904967812338475	[84]	[211]	-1	hSpCas9	negative selection	2321712
15524171	15524194	1	-	24717434	HeLa	essential genes for diphteria toxin toxicity	AAGCGGATCGGCGGCTCCTGCGG	CASP9	ENSG00000132906	0.12577756200066936	[2403,2041,2484]	[0,0,0]	0	hSpCas9	positive selection	2380669
15524162	15524184	1	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GCGGCTCCTGCGGCGGTGCCGG	CASP9	ENSG00000132906	2.6525969031046803	[433,400,368]	[0,0,0]	6	hSpCas9	positive selection	2380670
15524077	15524102	1	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CTGTTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	-0.23713226078290084	[2713,2682,3487]	[0,0,0]	-2	hSpCas9	positive selection	2380671
15524171	15524194	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AAGCGGATCGGCGGCTCCTGCGG	CASP9	ENSG00000132906	2.126043734773658	[2403,2041,2484]	[0,9,0]	4	hSpCas9	positive selection	2381819
15524171	15524194	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AAGCGGATCGGCGGCTCCTGCGG	CASP9	ENSG00000132906	2.126043734773658	[2403,2041,2484]	[0,9,0]	4	hSpCas9	positive selection	2381820
15524171	15524194	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	AAGCGGATCGGCGGCTCCTGCGG	CASP9	ENSG00000132906	2.126043734773658	[2403,2041,2484]	[0,9,0]	4	hSpCas9	positive selection	2381821
15524162	15524184	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCGGCTCCTGCGGCGGTGCCGG	CASP9	ENSG00000132906	3.8745934213348288	[433,400,368]	[2,2,0]	6	hSpCas9	positive selection	2381822
15524162	15524184	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCGGCTCCTGCGGCGGTGCCGG	CASP9	ENSG00000132906	3.8745934213348288	[433,400,368]	[2,2,0]	6	hSpCas9	positive selection	2381823
15524162	15524184	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCGGCTCCTGCGGCGGTGCCGG	CASP9	ENSG00000132906	3.8745934213348288	[433,400,368]	[2,2,0]	6	hSpCas9	positive selection	2381824
15524077	15524102	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTGTTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	3.9063038297086123	[2713,2682,3487]	[0,50,0]	7	hSpCas9	positive selection	2381825
15524077	15524102	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTGTTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	3.9063038297086123	[2713,2682,3487]	[0,50,0]	7	hSpCas9	positive selection	2381826
15524077	15524102	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTGTTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	3.9063038297086123	[2713,2682,3487]	[0,50,0]	7	hSpCas9	positive selection	2381827
15524527	15524550	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGACGCAGTGGTGGATTCTGG	CASP9	ENSG00000132906	-1.7050815349151403	[0,51]	[0,1]	-8	dCas9-VP64	positive selection	2413040
15524571	15524594	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTGACGTGAGGTCAGTGCGGGG	CASP9	ENSG00000132906	2.592436331005833	[0,21]	[9,20]	8	dCas9-VP64	positive selection	2413041
15524615	15524638	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGAGATGCGTCCTGCGGGCGGG	CASP9	ENSG00000132906	1.3028298938044736	[13,34]	[3,22]	5	dCas9-VP64	positive selection	2413042
15511662	15511685	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTGATCCCAGCACTTGGG	CASP9	ENSG00000132906	-0.36624742611917555	[139,91]	[7,31]	-2	dCas9-VP64	positive selection	2425064
15518898	15518921	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCACTCTGTCACCCAGG	CASP9	ENSG00000132906	0.5662063265134789	[296,266]	[152,24]	2	dCas9-VP64	positive selection	2439480
15524926	15524949	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGATTGACCTTGGGGGCGGGG	CASP9	ENSG00000132906	-0.4987369687902041	[40,15]	[4,2]	-2	dCas9-VP64	positive selection	2460389
15524859	15524882	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGATTCTGGGGTCGGCGCGAGG	CASP9	ENSG00000132906	3.020719161580856	[47,83]	[100,137]	8	dCas9-VP64	positive selection	2460390
15524903	15524926	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGGGCGTGGGTTGAATCCTGG	CASP9	ENSG00000132906	0.8606001816178749	[78,85]	[21,43]	3	dCas9-VP64	positive selection	2460391
15524527	15524550	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGACGCAGTGGTGGATTCTGG	CASP9	ENSG00000132906	2.2769108840239114	[1,11]	[1,18]	8	dCas9-VP64	positive selection	2508295
15524571	15524594	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTGACGTGAGGTCAGTGCGGGG	CASP9	ENSG00000132906	-1.6068637288864853	[30,207]	[9,13]	-9	dCas9-VP64	positive selection	2508296
15524615	15524638	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGAGATGCGTCCTGCGGGCGGG	CASP9	ENSG00000132906	0.7331405574332461	[126,121]	[45,87]	5	dCas9-VP64	positive selection	2508297
15511662	15511685	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTGATCCCAGCACTTGGG	CASP9	ENSG00000132906	0.7408412199076642	[275,405]	[66,295]	5	dCas9-VP64	positive selection	2520319
15518898	15518921	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCACTCTGTCACCCAGG	CASP9	ENSG00000132906	-0.8868396810076964	[300,188]	[54,31]	-8	dCas9-VP64	positive selection	2534735
15524926	15524949	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGATTGACCTTGGGGGCGGGG	CASP9	ENSG00000132906	0.1985772528678038	[64,101]	[45,15]	1	dCas9-VP64	positive selection	2555644
15524859	15524882	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGATTCTGGGGTCGGCGCGAGG	CASP9	ENSG00000132906	0.37118516573535	[31,24]	[11,10]	3	dCas9-VP64	positive selection	2555645
15524903	15524926	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGGGCGTGGGTTGAATCCTGG	CASP9	ENSG00000132906	0.8298421096257866	[220,66]	[147,24]	5	dCas9-VP64	positive selection	2555646
15518129	15518152	1	+	27013184	SW480	treatment with recombinant TRAIL	AGAACCAATGTCCACTGGTCTGG	CASP9	ENSG00000132906	0.5224937447940713	[167,271]	[194,45]	2	hSpCas9	positive selection	2959884
15524068	15524091	1	+	27013184	SW480	treatment with recombinant TRAIL	CCTGGATGTCCTCGATCATATGG	CASP9	ENSG00000132906	-0.9201410189760592	[273,569]	[39,168]	-4	hSpCas9	positive selection	2959885
15524069	15524092	1	+	27013184	SW480	treatment with recombinant TRAIL	CTGGATGTCCTCGATCATATGGG	CASP9	ENSG00000132906	1.0676069931011765	[891,742]	[810,651]	5	hSpCas9	positive selection	2959886
15524070	15524093	1	+	27013184	SW480	treatment with recombinant TRAIL	TGGATGTCCTCGATCATATGGGG	CASP9	ENSG00000132906	1.7764539737785512	[209,201]	[328,270]	7	hSpCas9	positive selection	2959887
15524086	15524109	1	+	27013184	SW480	treatment with recombinant TRAIL	TATGGGGCCTGAACAGCTCGCGG	CASP9	ENSG00000132906	0.44719447512146104	[196,328]	[102,219]	2	hSpCas9	positive selection	2959888
15524095	15524118	1	+	27013184	SW480	treatment with recombinant TRAIL	TGAACAGCTCGCGGCTCAGCAGG	CASP9	ENSG00000132906	1.2353635191250414	[271,320]	[362,207]	6	hSpCas9	positive selection	2959889
15524110	15524133	1	+	27013184	SW480	treatment with recombinant TRAIL	TCAGCAGGGCGTCCCAGAGCTGG	CASP9	ENSG00000132906	-0.22529700209290882	[573,560]	[134,315]	-1	hSpCas9	positive selection	2959890
15524143	15524166	1	+	27013184	SW480	treatment with recombinant TRAIL	GCTCTTCCACCAGCCGCAGCCGG	CASP9	ENSG00000132906	0.9591133536187342	[1130,1155]	[1094,763]	4	hSpCas9	positive selection	2959891
15518263	15518286	1	+	27013184	SW480	treatment with recombinant TRAIL	GAAACGAAGCCAGCATGTCCTGG	CASP9	ENSG00000132906	-2.781644147537871	[419,492]	[39,11]	-8	hSpCas9	positive selection	2959892
15518282	15518305	1	+	27013184	SW480	treatment with recombinant TRAIL	CTGGCCTGTGTCCTCTAAGCAGG	CASP9	ENSG00000132906	0.5468287251826733	[642,841]	[367,596]	2	hSpCas9	positive selection	2959893
15518295	15518318	1	+	27013184	SW480	treatment with recombinant TRAIL	TCTAAGCAGGAGATGAACAAAGG	CASP9	ENSG00000132906	-0.33358873395093425	[172,80]	[41,48]	-1	hSpCas9	positive selection	2959894
15518342	15518365	1	+	27013184	SW480	treatment with recombinant TRAIL	CAGATCTATGATCAGCTGCCTGG	CASP9	ENSG00000132906	-1.2059675442809996	[225,132]	[9,68]	-5	hSpCas9	positive selection	2959895
15518390	15518413	1	+	27013184	SW480	treatment with recombinant TRAIL	TGCCCGCTGTTTGGAAAGAAAGG	CASP9	ENSG00000132906	0.08269426966358889	[197,236]	[39,181]	0	hSpCas9	positive selection	2959896
15518394	15518417	1	+	27013184	SW480	treatment with recombinant TRAIL	CGCTGTTTGGAAAGAAAGGCAGG	CASP9	ENSG00000132906	-0.3724886897096935	[5,5]	[1,1]	-2	hSpCas9	positive selection	2959897
15518133	15518156	1	-	27013184	SW480	treatment with recombinant TRAIL	ACACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	-0.2652215736318518	[246,124]	[31,120]	-1	hSpCas9	positive selection	2959898
15518200	15518223	1	-	27013184	SW480	treatment with recombinant TRAIL	CCTAGAAAACCTTACCCCAGTGG	CASP9	ENSG00000132906	2.165510739952329	[156,275]	[398,422]	8	hSpCas9	positive selection	2959899
15518249	15518272	1	-	27013184	SW480	treatment with recombinant TRAIL	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.5380026220146108	[36,69]	[25,41]	2	hSpCas9	positive selection	2959900
15518154	15518177	1	+	27013184	SW480	treatment with recombinant TRAIL	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	-2.1134779830836767	[570,681]	[42,88]	-7	hSpCas9	positive selection	2959901
15518286	15518309	1	-	27013184	SW480	treatment with recombinant TRAIL	ATCTCCTGCTTAGAGGACACAGG	CASP9	ENSG00000132906	-0.6749546365294866	[144,103]	[48,12]	-3	hSpCas9	positive selection	2959902
15518293	15518316	1	-	27013184	SW480	treatment with recombinant TRAIL	TTTGTTCATCTCCTGCTTAGAGG	CASP9	ENSG00000132906	-1.8868104751153285	[440,675]	[32,107]	-7	hSpCas9	positive selection	2959903
15518330	15518353	1	-	27013184	SW480	treatment with recombinant TRAIL	TCATAGATCTGGAGACTCGAGGG	CASP9	ENSG00000132906	0.6344530255984931	[254,216]	[112,224]	3	hSpCas9	positive selection	2959904
15518331	15518354	1	-	27013184	SW480	treatment with recombinant TRAIL	ATCATAGATCTGGAGACTCGAGG	CASP9	ENSG00000132906	-0.6244837885199133	[67,92]	[1,50]	-3	hSpCas9	positive selection	2959905
15518341	15518364	1	-	27013184	SW480	treatment with recombinant TRAIL	CAGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.7958224963793408	[633,778]	[398,702]	4	hSpCas9	positive selection	2959906
15518360	15518383	1	-	27013184	SW480	treatment with recombinant TRAIL	GATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	-2.881238296353621	[359,473]	[19,29]	-8	hSpCas9	positive selection	2959907
15518365	15518388	1	-	27013184	SW480	treatment with recombinant TRAIL	CTCTGGATCTCGGCGGGATCAGG	CASP9	ENSG00000132906	0.11568760810710255	[400,474]	[194,214]	0	hSpCas9	positive selection	2959908
15518375	15518398	1	-	27013184	SW480	treatment with recombinant TRAIL	AGCGGGCAGGCTCTGGATCTCGG	CASP9	ENSG00000132906	1.118917296486824	[219,297]	[177,326]	5	hSpCas9	positive selection	2959909
15518382	15518405	1	-	27013184	SW480	treatment with recombinant TRAIL	TCCAAACAGCGGGCAGGCTCTGG	CASP9	ENSG00000132906	-6.341550144669449	[204,579]	[1,1]	-9	hSpCas9	positive selection	2959910
15518388	15518411	1	-	27013184	SW480	treatment with recombinant TRAIL	TTTCTTTCCAAACAGCGGGCAGG	CASP9	ENSG00000132906	1.575043890396171	[15,15]	[1,46]	7	hSpCas9	positive selection	2959911
15518392	15518415	1	-	27013184	SW480	treatment with recombinant TRAIL	TGCCTTTCTTTCCAAACAGCGGG	CASP9	ENSG00000132906	-0.16882444301806807	[195,300]	[86,102]	0	hSpCas9	positive selection	2959912
15518393	15518416	1	-	27013184	SW480	treatment with recombinant TRAIL	CTGCCTTTCTTTCCAAACAGCGG	CASP9	ENSG00000132906	0.6980796784190777	[285,125]	[220,46]	3	hSpCas9	positive selection	2959913
15524188	15524211	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.19837181940601648	[2,3]	[1,1]	-3	hSpCas9	positive selection	2976435
15524087	15524110	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TATGGGGCCTGAACAGCTCGCGG	CASP9	ENSG00000132906	-0.6190785941043595	[2,3]	[2,0]	-7	hSpCas9	positive selection	2976436
15518330	15518353	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCATAGATCTGGAGACTCGAGGG	CASP9	ENSG00000132906	-0.3337900113208516	[3,3]	[4,0]	-5	hSpCas9	positive selection	2976437
15518296	15518319	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTAAGCAGGAGATGAACAAAGG	CASP9	ENSG00000132906	-0.3010068409439201	[3,3]	[2,1]	-4	hSpCas9	positive selection	2976438
15524188	15524211	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.6245815018958669	[2,2]	[1,4]	8	hSpCas9	positive selection	3044293
15524087	15524110	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TATGGGGCCTGAACAGCTCGCGG	CASP9	ENSG00000132906	-0.11583250815498256	[2,2]	[1,1]	-2	hSpCas9	positive selection	3044294
15518330	15518353	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCATAGATCTGGAGACTCGAGGG	CASP9	ENSG00000132906	0.05181597550059881	[3,3]	[3,1]	0	hSpCas9	positive selection	3044295
15518296	15518319	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTAAGCAGGAGATGAACAAAGG	CASP9	ENSG00000132906	-0.39566797688080496	[3,3]	[3,0]	-6	hSpCas9	positive selection	3044296
15518341	15518364		-	24336571	A375	resistance to PLX after 7 days	CAGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	-0.18854618480156762	[12,12]	[11,10]	-6	hSpCas9	positive selection	3160762
15507888	15507911		-	24336571	A375	resistance to PLX after 7 days	CAGGTGCTCTTGAGAGTTTGAGG	CASP9	ENSG00000132906	-0.30708623695120785	[14,19]	[14,11]	-8	hSpCas9	positive selection	3160763
15518249	15518272		-	24336571	A375	resistance to PLX after 7 days	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	-0.014548225519322264	[11,11]	[10,12]	0	hSpCas9	positive selection	3160764
15518341	15518364		-	24336571	A375	resistance to PLX after 14 days	CAGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	-0.5844475547886638	[10,12]	[3,1]	-7	hSpCas9	positive selection	3218555
15507888	15507911		-	24336571	A375	resistance to PLX after 14 days	CAGGTGCTCTTGAGAGTTTGAGG	CASP9	ENSG00000132906	-0.1571418998531801	[13,18]	[5,6]	-2	hSpCas9	positive selection	3218556
15518249	15518272		-	24336571	A375	resistance to PLX after 14 days	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	-0.8370243828433058	[12,17]	[3,2]	-8	hSpCas9	positive selection	3218557
15518341	15518364		-	24336571	A375	viability after 7 days	CAGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.44570090698318826	[9]	[12,12]	6	hSpCas9	negative selection	3276348
15507888	15507911		-	24336571	A375	viability after 7 days	CAGGTGCTCTTGAGAGTTTGAGG	CASP9	ENSG00000132906	0.5347182332833678	[11]	[14,19]	7	hSpCas9	negative selection	3276349
15518249	15518272		-	24336571	A375	viability after 7 days	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	-1.042480678060147	[26]	[11,11]	-9	hSpCas9	negative selection	3276350
15518341	15518364		-	24336571	A375	viability after 14 days	CAGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.3671211355876827	[9]	[10,12]	5	hSpCas9	negative selection	3334141
15507888	15507911		-	24336571	A375	viability after 14 days	CAGGTGCTCTTGAGAGTTTGAGG	CASP9	ENSG00000132906	0.4960857517770001	[11]	[13,18]	6	hSpCas9	negative selection	3334142
15518249	15518272		-	24336571	A375	viability after 14 days	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	-0.6407268809473546	[26]	[12,17]	-7	hSpCas9	negative selection	3334143
15518249	15518272	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.2379353489025191	[164,93]	[0,0]	1	hSpCas9	positive selection	3341142
15506019	15506042	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	1.88467450148239	[30,51]	[0,0]	7	hSpCas9	positive selection	3341143
15518154	15518177	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.47579506484618445	[111,107]	[0,0]	2	hSpCas9	positive selection	3341144
15507002	15507025	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	1.1280431945008687	[69,69]	[0,0]	5	hSpCas9	positive selection	3360390
15506959	15506982	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.9225828785690994	[289,289]	[0,0]	-6	hSpCas9	positive selection	3360391
15505989	15506012	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.07741712143090063	[289,289]	[1,1]	0	hSpCas9	positive selection	3360392
15524188	15524211	1	-	26780180	HT29	viability (Avana library 4 designs)	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.556536020403577	[]	[]	2	hSpCas9	negative selection	3412716
15524086	15524109	1	+	26780180	HT29	viability (Avana library 4 designs)	TATGGGGCCTGAACAGCTCGCGG	CASP9	ENSG00000132906	1.74720663223743	[]	[]	6	hSpCas9	negative selection	3412717
15518330	15518353	1	-	26780180	HT29	viability (Avana library 4 designs)	TCATAGATCTGGAGACTCGAGGG	CASP9	ENSG00000132906	0.928538861565342	[]	[]	3	hSpCas9	negative selection	3412718
15518295	15518318	1	+	26780180	HT29	viability (Avana library 4 designs)	TCTAAGCAGGAGATGAACAAAGG	CASP9	ENSG00000132906	1.77211864856422	[]	[]	6	hSpCas9	negative selection	3412719
15518330	15518353	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCATAGATCTGGAGACTCGAGGG	CASP9	ENSG00000132906	-5.40847383978456	[]	[]	-5	hSpCas9	negative selection	3488322
15524188	15524211	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.523184056530355	[]	[]	0	hSpCas9	negative selection	3488323
15524086	15524109	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TATGGGGCCTGAACAGCTCGCGG	CASP9	ENSG00000132906	2.54208298868027	[]	[]	4	hSpCas9	negative selection	3488324
15518295	15518318	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTAAGCAGGAGATGAACAAAGG	CASP9	ENSG00000132906	-5.73599841461154	[]	[]	-6	hSpCas9	negative selection	3488325
15524180	15524203	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCATGGACGAAGCGGATCGGCGG	CASP9	ENSG00000132906	1.45615543011344	[]	[]	2	hSpCas9	negative selection	3488326
15524096	15524119	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAACAGCTCGCGGCTCAGCAGGG	CASP9	ENSG00000132906	6.2172361328171	[]	[]	9	hSpCas9	negative selection	3488327
15518330	15518353	1	-	26780180	A375	viability (Avana lentiGuide)	TCATAGATCTGGAGACTCGAGGG	CASP9	ENSG00000132906	-1.32460284786232	[]	[]	-2	hSpCas9	negative selection	3596981
15524188	15524211	1	-	26780180	A375	viability (Avana lentiGuide)	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	1.32497332570482	[]	[]	1	hSpCas9	negative selection	3596982
15524086	15524109	1	+	26780180	A375	viability (Avana lentiGuide)	TATGGGGCCTGAACAGCTCGCGG	CASP9	ENSG00000132906	-5.11562733013043	[]	[]	-8	hSpCas9	negative selection	3596983
15518295	15518318	1	+	26780180	A375	viability (Avana lentiGuide)	TCTAAGCAGGAGATGAACAAAGG	CASP9	ENSG00000132906	3.51463820039444	[]	[]	3	hSpCas9	negative selection	3596984
15524180	15524203	1	-	26780180	A375	viability (Avana lentiGuide)	CCATGGACGAAGCGGATCGGCGG	CASP9	ENSG00000132906	4.72897986371817	[]	[]	4	hSpCas9	negative selection	3596985
15524096	15524119	1	+	26780180	A375	viability (Avana lentiGuide)	GAACAGCTCGCGGCTCAGCAGGG	CASP9	ENSG00000132906	-2.45943142763772	[]	[]	-4	hSpCas9	negative selection	3596986
15518330	15518353	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATAGATCTGGAGACTCGAGGG	CASP9	ENSG00000132906	-0.40320194930240605	[5]	[4,3]	-5	hSpCas9	positive selection	3705640
15524188	15524211	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.4551032631313038	[4]	[3,2]	-6	hSpCas9	positive selection	3705641
15524086	15524109	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TATGGGGCCTGAACAGCTCGCGG	CASP9	ENSG00000132906	-0.0852661402284989	[4]	[4,3]	-1	hSpCas9	positive selection	3705642
15518295	15518318	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTAAGCAGGAGATGAACAAAGG	CASP9	ENSG00000132906	-0.11149548354041663	[5]	[5,4]	-2	hSpCas9	positive selection	3705643
15524180	15524203	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATGGACGAAGCGGATCGGCGG	CASP9	ENSG00000132906	0.22465134380899088	[3]	[4,4]	6	hSpCas9	positive selection	3705644
15524096	15524119	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAACAGCTCGCGGCTCAGCAGGG	CASP9	ENSG00000132906	0.1709673681815643	[5]	[6,5]	4	hSpCas9	positive selection	3705645
15518330	15518353	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATAGATCTGGAGACTCGAGGG	CASP9	ENSG00000132906	0.22332579428906607	[4]	[4,5]	6	hSpCas9	positive selection	3814247
15524188	15524211	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.3858920036221617	[5]	[2,3]	-5	hSpCas9	positive selection	3814248
15524086	15524109	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TATGGGGCCTGAACAGCTCGCGG	CASP9	ENSG00000132906	0.025397026057273397	[4]	[4,3]	0	hSpCas9	positive selection	3814249
15518295	15518318	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTAAGCAGGAGATGAACAAAGG	CASP9	ENSG00000132906	0.09681559280290619	[5]	[5,4]	2	hSpCas9	positive selection	3814250
15524180	15524203	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATGGACGAAGCGGATCGGCGG	CASP9	ENSG00000132906	-0.015918156590157995	[5]	[2,5]	0	hSpCas9	positive selection	3814251
15524096	15524119	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAACAGCTCGCGGCTCAGCAGGG	CASP9	ENSG00000132906	0.3584357238056819	[6]	[6,7]	9	hSpCas9	positive selection	3814252
15506959	15506982	1	+	26780180	A375	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	1.32320822604705	[]	[]	7	hSpCas9	negative selection	3922553
15505989	15506012	1	-	26780180	A375	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.955971270762504	[]	[]	4	hSpCas9	negative selection	3922554
15506019	15506042	1	+	26780180	A375	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	1.02012130366402	[]	[]	5	hSpCas9	negative selection	3922555
15518249	15518272	1	-	26780180	A375	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.962702150067619	[]	[]	4	hSpCas9	negative selection	3922556
15507002	15507025	1	-	26780180	A375	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.871243489463585	[]	[]	3	hSpCas9	negative selection	3922557
15518154	15518177	1	+	26780180	A375	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	1.30417410944834	[]	[]	7	hSpCas9	negative selection	3922558
15506959	15506982	1	+	26780180	HT29	viability (GeCKOv2 library)	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	0.922605016568676	[]	[]	4	hSpCas9	negative selection	4030519
15505989	15506012	1	-	26780180	HT29	viability (GeCKOv2 library)	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.51140642782905	[]	[]	1	hSpCas9	negative selection	4030520
15506019	15506042	1	+	26780180	HT29	viability (GeCKOv2 library)	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.90792268549579	[]	[]	4	hSpCas9	negative selection	4030521
15518249	15518272	1	-	26780180	HT29	viability (GeCKOv2 library)	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	1.10588921923174	[]	[]	5	hSpCas9	negative selection	4030522
15507002	15507025	1	-	26780180	HT29	viability (GeCKOv2 library)	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	1.16036148746306	[]	[]	5	hSpCas9	negative selection	4030523
15518154	15518177	1	+	26780180	HT29	viability (GeCKOv2 library)	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	1.6261410931456	[]	[]	8	hSpCas9	negative selection	4030524
15518341	15518364	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	-0.15815604303665026	[3]	[2,1]	-4	hSpCas9	positive selection	4188855
15507888	15507911	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGGTGCTCTTGAGAGTTTGAGG	CASP9	ENSG00000132906	0.03305727794341298	[4]	[2,2]	0	hSpCas9	positive selection	4188856
15518249	15518272	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	-0.1342573410706962	[3]	[2,1]	-3	hSpCas9	positive selection	4188857
15518341	15518364	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.9396553122663862	[2]	[4,3,0,0]	6	hSpCas9	positive selection	4252877
15507888	15507911	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGGTGCTCTTGAGAGTTTGAGG	CASP9	ENSG00000132906	-0.004578719490138328	[3]	[1,1,3,0]	0	hSpCas9	positive selection	4252878
15518249	15518272	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.8324640145436255	[4]	[4,3,1,3]	5	hSpCas9	positive selection	4252879
15518249	15518272	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.09223540470040523	[3]	[3,1]	1	hSpCas9	positive selection	4261030
15506019	15506042	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.26625220105950115	[1]	[1,0]	-5	hSpCas9	positive selection	4261031
15518154	15518177	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	-0.05134000997738465	[2]	[2,1]	-1	hSpCas9	positive selection	4261032
15507002	15507025	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	-0.18581482592366516	[1]	[1,0]	-4	hSpCas9	positive selection	4325308
15506959	15506982	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.2234963747141406	[3]	[2,1]	-4	hSpCas9	positive selection	4325309
15505989	15506012	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.21470355601849384	[3]	[3,2]	4	hSpCas9	positive selection	4325310
15506067	15506089	1	-	27760321	OCIAML3	viability	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	-0.49152730929333766	[491,454]	[196,349]	-5	hSpCas9	negative selection	4385832
15506890	15506912	1	+	27760321	OCIAML3	viability	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	-0.21122837635400926	[1000,825]	[421,864]	-2	hSpCas9	negative selection	4385833
15506972	15506994	1	+	27760321	OCIAML3	viability	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.6180751953619965	[641,587]	[324,297]	-6	hSpCas9	negative selection	4385834
15518133	15518155	1	-	27760321	OCIAML3	viability	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.7842621580266411	[641,501]	[578,1007]	8	hSpCas9	negative selection	4385835
15518170	15518192	1	-	27760321	OCIAML3	viability	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.5483300871145169	[500,393]	[448,585]	6	hSpCas9	negative selection	4385836
15518341	15518363	1	-	27760321	OCIAML3	viability	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.5779963223530861	[351,262]	[328,390]	7	hSpCas9	negative selection	4385837
15518360	15518382	1	-	27760321	OCIAML3	viability	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	0.5652369145491241	[172,594]	[408,539]	6	hSpCas9	negative selection	4385838
15524077	15524099	1	-	27760321	OCIAML3	viability	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	-0.033191725945013295	[705,576]	[509,458]	0	hSpCas9	negative selection	4385839
15506067	15506089	1	-	27760321	OCIAML2	viability	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	0.3406233123350655	[491,454]	[409,583]	4	hSpCas9	negative selection	4469295
15506890	15506912	1	+	27760321	OCIAML2	viability	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	-0.004830228473439391	[1000,825]	[607,897]	0	hSpCas9	negative selection	4469296
15506972	15506994	1	+	27760321	OCIAML2	viability	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.017292070377446345	[641,587]	[449,545]	0	hSpCas9	negative selection	4469297
15518133	15518155	1	-	27760321	OCIAML2	viability	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.5966491094401363	[641,501]	[527,914]	7	hSpCas9	negative selection	4469298
15518170	15518192	1	-	27760321	OCIAML2	viability	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.5531623187403172	[500,393]	[465,608]	7	hSpCas9	negative selection	4469299
15518341	15518363	1	-	27760321	OCIAML2	viability	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.5610519375227012	[351,262]	[302,443]	7	hSpCas9	negative selection	4469300
15518360	15518382	1	-	27760321	OCIAML2	viability	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	0.6452508833297335	[172,594]	[498,522]	8	hSpCas9	negative selection	4469301
15524077	15524099	1	-	27760321	OCIAML2	viability	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.48950759595023197	[705,576]	[604,882]	6	hSpCas9	negative selection	4469302
15506067	15506089	1	-	27760321	MV411	viability	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	-0.3494728156658225	[491,454]	[78,494]	-2	hSpCas9	negative selection	4552758
15506890	15506912	1	+	27760321	MV411	viability	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	1.0181945382112683	[1000,825]	[913,1667]	7	hSpCas9	negative selection	4552759
15506972	15506994	1	+	27760321	MV411	viability	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.5002708512759176	[641,587]	[413,813]	3	hSpCas9	negative selection	4552760
15518133	15518155	1	-	27760321	MV411	viability	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	-0.8774751758756549	[641,501]	[48,436]	-5	hSpCas9	negative selection	4552761
15518170	15518192	1	-	27760321	MV411	viability	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	1.809117592315299	[500,393]	[1119,889]	9	hSpCas9	negative selection	4552762
15518341	15518363	1	-	27760321	MV411	viability	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	1.3972494673633062	[351,262]	[160,1083]	8	hSpCas9	negative selection	4552763
15518360	15518382	1	-	27760321	MV411	viability	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	1.1746625910689572	[172,594]	[249,1124]	8	hSpCas9	negative selection	4552764
15524077	15524099	1	-	27760321	MV411	viability	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	1.1153578230128447	[705,576]	[1121,597]	7	hSpCas9	negative selection	4552765
15506067	15506089	1	-	27760321	HL60	viability	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	-0.48332892453229065	[491,454]	[299,251]	-5	hSpCas9	negative selection	4636221
15506890	15506912	1	+	27760321	HL60	viability	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	0.32109079648924177	[1000,825]	[876,981]	4	hSpCas9	negative selection	4636222
15506972	15506994	1	+	27760321	HL60	viability	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.45112266549102487	[641,587]	[312,424]	-5	hSpCas9	negative selection	4636223
15518133	15518155	1	-	27760321	HL60	viability	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	-0.1918986018225736	[641,501]	[415,395]	-2	hSpCas9	negative selection	4636224
15518170	15518192	1	-	27760321	HL60	viability	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.5517510601862394	[500,393]	[659,396]	6	hSpCas9	negative selection	4636225
15518341	15518363	1	-	27760321	HL60	viability	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.44889102185371677	[351,262]	[237,447]	5	hSpCas9	negative selection	4636226
15518360	15518382	1	-	27760321	HL60	viability	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	0.27676677778995756	[172,594]	[444,348]	3	hSpCas9	negative selection	4636227
15524077	15524099	1	-	27760321	HL60	viability	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.6085544402372487	[705,576]	[679,916]	7	hSpCas9	negative selection	4636228
15506067	15506089	1	-	27760321	HT1080	viability	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	-0.27393398608334335	[454,354]	[110,157]	-1	hSpCas9	negative selection	4719684
15506890	15506912	1	+	27760321	HT1080	viability	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	-0.2752626127932871	[825,644]	[370,100]	-1	hSpCas9	negative selection	4719685
15506972	15506994	1	+	27760321	HT1080	viability	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-1.0341878434187435	[587,458]	[150,47]	-4	hSpCas9	negative selection	4719686
15518133	15518155	1	-	27760321	HT1080	viability	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	-2.658274555128307	[501,391]	[0,57]	-7	hSpCas9	negative selection	4719687
15518170	15518192	1	-	27760321	HT1080	viability	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	1.2247542690325148	[393,307]	[238,422]	6	hSpCas9	negative selection	4719688
15518341	15518363	1	-	27760321	HT1080	viability	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.06130898482416425	[262,204]	[49,148]	0	hSpCas9	negative selection	4719689
15518360	15518382	1	-	27760321	HT1080	viability	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	1.2327269348608434	[594,463]	[383,617]	6	hSpCas9	negative selection	4719690
15524077	15524099	1	-	27760321	HT1080	viability	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.8014691599960073	[576,449]	[419,286]	4	hSpCas9	negative selection	4719691
15506067	15506089	1	-	27760321	HT29	viability after 7 days	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	-0.2801678888171608	[454,354]	[537,291,469]	-4	hSpCas9	negative selection	4803147
15506890	15506912	1	+	27760321	HT29	viability after 7 days	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	-0.3054022931622914	[825,644]	[817,935,554]	-4	hSpCas9	negative selection	4803148
15506972	15506994	1	+	27760321	HT29	viability after 7 days	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.495036689437031	[587,458]	[757,330,385]	-6	hSpCas9	negative selection	4803149
15518133	15518155	1	-	27760321	HT29	viability after 7 days	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.7079765535168128	[501,391]	[993,921,907]	9	hSpCas9	negative selection	4803150
15518170	15518192	1	-	27760321	HT29	viability after 7 days	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.6601430618274	[393,307]	[904,644,618]	8	hSpCas9	negative selection	4803151
15518341	15518363	1	-	27760321	HT29	viability after 7 days	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.4044352234668517	[262,204]	[454,410,337]	6	hSpCas9	negative selection	4803152
15518360	15518382	1	-	27760321	HT29	viability after 7 days	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	0.04601608332894014	[594,463]	[604,706,778]	0	hSpCas9	negative selection	4803153
15524077	15524099	1	-	27760321	HT29	viability after 7 days	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.4908481516373979	[576,449]	[1122,672,1010]	7	hSpCas9	negative selection	4803154
15506067	15506089	1	-	27760321	HT29	viability after 25 days	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	-0.23639822916890518	[454,354]	[319,414,453]	-3	hSpCas9	negative selection	4886610
15506890	15506912	1	+	27760321	HT29	viability after 25 days	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	-0.02848834838026626	[825,644]	[729,716,1053]	0	hSpCas9	negative selection	4886611
15506972	15506994	1	+	27760321	HT29	viability after 25 days	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.1211529923547055	[587,458]	[529,498,629]	-1	hSpCas9	negative selection	4886612
15518133	15518155	1	-	27760321	HT29	viability after 25 days	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.5492126359575811	[501,391]	[528,816,927]	6	hSpCas9	negative selection	4886613
15518170	15518192	1	-	27760321	HT29	viability after 25 days	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.40298131477469845	[393,307]	[321,506,802]	4	hSpCas9	negative selection	4886614
15518341	15518363	1	-	27760321	HT29	viability after 25 days	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.8208989574854474	[262,204]	[354,490,589]	8	hSpCas9	negative selection	4886615
15518360	15518382	1	-	27760321	HT29	viability after 25 days	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	-0.1634761022592049	[594,463]	[592,471,552]	-2	hSpCas9	negative selection	4886616
15524077	15524099	1	-	27760321	HT29	viability after 25 days	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.638872465925229	[576,449]	[1008,843,876]	7	hSpCas9	negative selection	4886617
15506067	15506089	1	-	27760321	HT29	viability after 22 days	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	-0.21982522979603755	[454,354]	[414,356,433]	-2	hSpCas9	negative selection	4970073
15506890	15506912	1	+	27760321	HT29	viability after 22 days	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	-0.16561413727130003	[825,644]	[881,617,770]	-2	hSpCas9	negative selection	4970074
15506972	15506994	1	+	27760321	HT29	viability after 22 days	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.21957749045450914	[587,458]	[1050,419,632]	2	hSpCas9	negative selection	4970075
15518133	15518155	1	-	27760321	HT29	viability after 22 days	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.6483361567225145	[501,391]	[683,862,886]	7	hSpCas9	negative selection	4970076
15518170	15518192	1	-	27760321	HT29	viability after 22 days	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.6737294045214356	[393,307]	[495,814,634]	7	hSpCas9	negative selection	4970077
15518341	15518363	1	-	27760321	HT29	viability after 22 days	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.4903541723666509	[262,204]	[336,330,473]	5	hSpCas9	negative selection	4970078
15518360	15518382	1	-	27760321	HT29	viability after 22 days	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	-0.20665721035379525	[594,463]	[409,492,692]	-2	hSpCas9	negative selection	4970079
15524077	15524099	1	-	27760321	HT29	viability after 22 days	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.4948655377490976	[576,449]	[1033,751,716]	5	hSpCas9	negative selection	4970080
15506067	15506089	1	-	27760321	HT29	viability after 19 days	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	0.20199936269903288	[454,354]	[1006,277,368]	1	hSpCas9	negative selection	5053536
15506890	15506912	1	+	27760321	HT29	viability after 19 days	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	0.11709924847086217	[825,644]	[801,827,1087]	1	hSpCas9	negative selection	5053537
15506972	15506994	1	+	27760321	HT29	viability after 19 days	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.2523251617627593	[587,458]	[853,486,808]	2	hSpCas9	negative selection	5053538
15518133	15518155	1	-	27760321	HT29	viability after 19 days	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.5239544563772696	[501,391]	[853,754,612]	5	hSpCas9	negative selection	5053539
15518170	15518192	1	-	27760321	HT29	viability after 19 days	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.5320179790616755	[393,307]	[675,276,789]	5	hSpCas9	negative selection	5053540
15518341	15518363	1	-	27760321	HT29	viability after 19 days	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.9374382233409064	[262,204]	[430,381,707]	8	hSpCas9	negative selection	5053541
15518360	15518382	1	-	27760321	HT29	viability after 19 days	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	0.22801116046818737	[594,463]	[631,613,866]	2	hSpCas9	negative selection	5053542
15524077	15524099	1	-	27760321	HT29	viability after 19 days	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.40466417587430503	[576,449]	[758,773,795]	4	hSpCas9	negative selection	5053543
15506067	15506089	1	-	27760321	HT29	viability after 16 days	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	0.07929757157533171	[454,354]	[400,390,638]	0	hSpCas9	negative selection	5136999
15506890	15506912	1	+	27760321	HT29	viability after 16 days	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	0.10026835871269357	[825,644]	[1217,651,813]	1	hSpCas9	negative selection	5137000
15506972	15506994	1	+	27760321	HT29	viability after 16 days	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.004365806488735746	[587,458]	[725,526,523]	0	hSpCas9	negative selection	5137001
15518133	15518155	1	-	27760321	HT29	viability after 16 days	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.48845767750328756	[501,391]	[841,627,649]	5	hSpCas9	negative selection	5137002
15518170	15518192	1	-	27760321	HT29	viability after 16 days	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.8255666776856329	[393,307]	[937,650,522]	8	hSpCas9	negative selection	5137003
15518341	15518363	1	-	27760321	HT29	viability after 16 days	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.9447029647894081	[262,204]	[510,664,331]	9	hSpCas9	negative selection	5137004
15518360	15518382	1	-	27760321	HT29	viability after 16 days	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	-0.2355398988551985	[594,463]	[574,546,392]	-3	hSpCas9	negative selection	5137005
15524077	15524099	1	-	27760321	HT29	viability after 16 days	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.459337956321321	[576,449]	[979,843,561]	5	hSpCas9	negative selection	5137006
15506067	15506089	1	-	27760321	HT29	viability after 13 days	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	-0.6990078788706882	[454,354]	[171,364,328]	-6	hSpCas9	negative selection	5220462
15506890	15506912	1	+	27760321	HT29	viability after 13 days	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	-0.19819101822097995	[825,644]	[665,781,780]	-2	hSpCas9	negative selection	5220463
15506972	15506994	1	+	27760321	HT29	viability after 13 days	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.2665500552559803	[587,458]	[662,802,725]	3	hSpCas9	negative selection	5220464
15518133	15518155	1	-	27760321	HT29	viability after 13 days	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.5237239699229079	[501,391]	[863,690,684]	6	hSpCas9	negative selection	5220465
15518170	15518192	1	-	27760321	HT29	viability after 13 days	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.5964490748142721	[393,307]	[576,582,682]	7	hSpCas9	negative selection	5220466
15518341	15518363	1	-	27760321	HT29	viability after 13 days	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.7410256723365544	[262,204]	[317,618,425]	8	hSpCas9	negative selection	5220467
15518360	15518382	1	-	27760321	HT29	viability after 13 days	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	-0.10539960705118462	[594,463]	[417,533,749]	-1	hSpCas9	negative selection	5220468
15524077	15524099	1	-	27760321	HT29	viability after 13 days	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.32396370964580357	[576,449]	[1008,562,668]	4	hSpCas9	negative selection	5220469
15506067	15506089	1	-	27760321	HT29	viability after 10 days	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	0.12653729374346603	[454,354]	[294,527,825]	1	hSpCas9	negative selection	5303925
15506890	15506912	1	+	27760321	HT29	viability after 10 days	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	0.10201304599519245	[825,644]	[947,1007,1000]	1	hSpCas9	negative selection	5303926
15506972	15506994	1	+	27760321	HT29	viability after 10 days	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.07460309949978494	[587,458]	[884,743,442]	1	hSpCas9	negative selection	5303927
15518133	15518155	1	-	27760321	HT29	viability after 10 days	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.4317651724035813	[501,391]	[631,858,769]	6	hSpCas9	negative selection	5303928
15518170	15518192	1	-	27760321	HT29	viability after 10 days	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	0.8755278536729391	[393,307]	[1311,752,355]	9	hSpCas9	negative selection	5303929
15518341	15518363	1	-	27760321	HT29	viability after 10 days	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	0.7350162615011737	[262,204]	[531,492,434]	8	hSpCas9	negative selection	5303930
15518360	15518382	1	-	27760321	HT29	viability after 10 days	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	0.0945941976537521	[594,463]	[560,519,1023]	1	hSpCas9	negative selection	5303931
15524077	15524099	1	-	27760321	HT29	viability after 10 days	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.5215346090715987	[576,449]	[938,736,1075]	7	hSpCas9	negative selection	5303932
15506067	15506089	1	-	27760321	MOLM13	viability	CTCTTGTAGAAAATGGTGCTGG	CASP9	ENSG00000132906	-0.20636481248847144	[491,454]	[102,340]	-1	hSpCas9	negative selection	5387388
15506890	15506912	1	+	27760321	MOLM13	viability	TGAGTGTACCTTGGCAGTCAGG	CASP9	ENSG00000132906	0.5520000306340827	[1000,825]	[1408,192]	4	hSpCas9	negative selection	5387389
15506972	15506994	1	+	27760321	MOLM13	viability	TCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.5747489058716281	[641,587]	[339,666]	4	hSpCas9	negative selection	5387390
15518133	15518155	1	-	27760321	MOLM13	viability	CACCCAGACCAGTGGACATTGG	CASP9	ENSG00000132906	0.25496043926192524	[641,501]	[321,433]	1	hSpCas9	negative selection	5387391
15518170	15518192	1	-	27760321	MOLM13	viability	CCAGAGATTCGCAAACCAGAGG	CASP9	ENSG00000132906	1.336044426577273	[500,393]	[508,738]	8	hSpCas9	negative selection	5387392
15518341	15518363	1	-	27760321	MOLM13	viability	AGGCAGCTGATCATAGATCTGG	CASP9	ENSG00000132906	1.014890918930656	[351,262]	[460,250]	7	hSpCas9	negative selection	5387393
15518360	15518382	1	-	27760321	MOLM13	viability	ATCTCGGCGGGATCAGGCCAGG	CASP9	ENSG00000132906	1.5163552267069953	[172,594]	[457,812]	9	hSpCas9	negative selection	5387394
15524077	15524099	1	-	27760321	MOLM13	viability	TTCAGGCCCCATATGATCGAGG	CASP9	ENSG00000132906	0.8241986381450754	[705,576]	[729,558]	6	hSpCas9	negative selection	5387395
15524025	15524048	1	+	27661255	K562	viability	GGGACCCGGCCGTGCAGCGCGGG	CASP9	ENSG00000132906	-0.08738333588982886	[720,672]	[582,474]	-3	dCas9-KRAB	negative selection	5468232
15524204	15524227	1	+	27661255	K562	viability	GAGTAGCCAACTAAGACTCCAGG	CASP9	ENSG00000132906	0.11404112784843451	[904,951]	[957,668]	4	dCas9-KRAB	negative selection	5468233
15524008	15524031	1	-	27661255	K562	viability	GGTCCCCACGCCCCTCGAGGAGG	CASP9	ENSG00000132906	0.18180630300415596	[983,1009]	[984,832]	6	dCas9-KRAB	negative selection	5468234
15524188	15524211	1	-	27661255	K562	viability	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.12945644699488823	[501,503]	[376,358]	-4	dCas9-KRAB	negative selection	5468235
15524227	15524250	1	-	27661255	K562	viability	GGCCCGGAAGCGGACTGAGGCGG	CASP9	ENSG00000132906	0.16277666585653755	[400,663]	[526,424]	5	dCas9-KRAB	negative selection	5468236
15524370	15524393	1	-	27661255	K562	viability	GACGCAAGAGCGACTCCTGGGGG	CASP9	ENSG00000132906	0.025296959864717583	[497,364]	[369,337]	0	dCas9-KRAB	negative selection	5468237
15518249	15518272	1	-	27260156	BXPC3	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.10331848564792234	[472]	[502,468,484,689]	2	hSpCas9	negative selection	5533490
15506019	15506042	1	+	27260156	BXPC3	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.04195883434651515	[195]	[200,113,272,214]	-1	hSpCas9	negative selection	5533491
15518154	15518177	1	+	27260156	BXPC3	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	-0.06772587864918661	[384]	[360,384,368,425]	-1	hSpCas9	negative selection	5533492
15507002	15507025	1	-	27260156	BXPC3	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.26859398318218464	[127]	[115,161,123,257]	6	hSpCas9	negative selection	5597768
15506959	15506982	1	+	27260156	BXPC3	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.4216731278230906	[678]	[408,637,532,544]	-7	hSpCas9	negative selection	5597769
15505989	15506012	1	-	27260156	BXPC3	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.10086243222046476	[622]	[580,687,732,815]	2	hSpCas9	negative selection	5597770
15518249	15518272	1	-	27260156	A673	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.10702141254706626	[472]	[652,542,552,708]	2	hSpCas9	negative selection	5654741
15506019	15506042	1	+	27260156	A673	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.14955570759387982	[195]	[315,159,302,273]	3	hSpCas9	negative selection	5654742
15518154	15518177	1	+	27260156	A673	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.26175373684273734	[384]	[665,519,478,565]	6	hSpCas9	negative selection	5654743
15507002	15507025	1	-	27260156	A673	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.31665334444532545	[127]	[228,163,103,278]	7	hSpCas9	negative selection	5719019
15506959	15506982	1	+	27260156	A673	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.24120595454579913	[678]	[809,603,713,642]	-5	hSpCas9	negative selection	5719020
15505989	15506012	1	-	27260156	A673	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.07194071929535134	[622]	[960,811,674,711]	1	hSpCas9	negative selection	5719021
15518249	15518272	1	-	27260156	A375	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.7146293266955467	[472]	[1123,1166,825,582]	9	hSpCas9	negative selection	5775992
15506019	15506042	1	+	27260156	A375	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.29971583122322953	[195]	[172,112,325,127]	-4	hSpCas9	negative selection	5775993
15518154	15518177	1	+	27260156	A375	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.3485340146682715	[384]	[356,717,606,618]	5	hSpCas9	negative selection	5775994
15507002	15507025	1	-	27260156	A375	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.2708857779708811	[127]	[245,122,123,215]	4	hSpCas9	negative selection	5840270
15506959	15506982	1	+	27260156	A375	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.5976256981706072	[678]	[523,545,499,526]	-7	hSpCas9	negative selection	5840271
15505989	15506012	1	-	27260156	A375	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.3417279867545555	[622]	[952,1190,835,761]	5	hSpCas9	negative selection	5840272
15518249	15518272	1	-	27260156	COLO741	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.0720863676581857	[472]	[818,524,579]	1	hSpCas9	negative selection	5897243
15506019	15506042	1	+	27260156	COLO741	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.2690928554126023	[195]	[290,341,272]	5	hSpCas9	negative selection	5897244
15518154	15518177	1	+	27260156	COLO741	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.22445897417889182	[384]	[650,653,434]	5	hSpCas9	negative selection	5897245
15507002	15507025	1	-	27260156	COLO741	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.18900786314103413	[127]	[233,88,235]	4	hSpCas9	negative selection	5961521
15506959	15506982	1	+	27260156	COLO741	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.3004084453608026	[678]	[701,709,699]	-6	hSpCas9	negative selection	5961522
15505989	15506012	1	-	27260156	COLO741	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.33938804439208736	[622]	[956,1078,980]	7	hSpCas9	negative selection	5961523
15518249	15518272	1	-	27260156	CAL120	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.23739538045628766	[472]	[776,687,629]	3	hSpCas9	negative selection	6018494
15506019	15506042	1	+	27260156	CAL120	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.4194843512573627	[195]	[511,255,239]	6	hSpCas9	negative selection	6018495
15518154	15518177	1	+	27260156	CAL120	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	-0.18194742871219582	[384]	[576,342,370]	-3	hSpCas9	negative selection	6018496
15507002	15507025	1	-	27260156	CAL120	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.16698534546146937	[127]	[150,245,135]	2	hSpCas9	negative selection	6082772
15506959	15506982	1	+	27260156	CAL120	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.6351082526055056	[678]	[436,644,533]	-7	hSpCas9	negative selection	6082773
15505989	15506012	1	-	27260156	CAL120	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.2514519792201577	[622]	[1124,659,1011]	4	hSpCas9	negative selection	6082774
15518249	15518272	1	-	27260156	CADOES1	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.23767110465348462	[472]	[425,512,591,544]	4	hSpCas9	negative selection	6139745
15506019	15506042	1	+	27260156	CADOES1	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.007359407682799857	[195]	[151,208,163,208]	0	hSpCas9	negative selection	6139746
15518154	15518177	1	+	27260156	CADOES1	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.0728379058655308	[384]	[331,411,325,438]	1	hSpCas9	negative selection	6139747
15507002	15507025	1	-	27260156	CADOES1	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.6021750644325765	[127]	[73,228,244,174]	8	hSpCas9	negative selection	6204023
15506959	15506982	1	+	27260156	CADOES1	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.5976882664299549	[678]	[325,425,562,351]	-8	hSpCas9	negative selection	6204024
15505989	15506012	1	-	27260156	CADOES1	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.4616746743202894	[622]	[837,709,832,810]	7	hSpCas9	negative selection	6204025
15518249	15518272	1	-	27260156	EWS502	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.2881427803872624	[472]	[636,401,636,786]	5	hSpCas9	negative selection	6260996
15506019	15506042	1	+	27260156	EWS502	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.22377316748106235	[195]	[235,126,199,139]	-4	hSpCas9	negative selection	6260997
15518154	15518177	1	+	27260156	EWS502	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.28009843189037653	[384]	[428,501,422,641]	5	hSpCas9	negative selection	6260998
15507002	15507025	1	-	27260156	EWS502	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.19417131668670717	[127]	[98,194,180,149]	3	hSpCas9	negative selection	6325274
15506959	15506982	1	+	27260156	EWS502	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.5011854265996424	[678]	[437,652,433,506]	-7	hSpCas9	negative selection	6325275
15505989	15506012	1	-	27260156	EWS502	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.21822122250586817	[622]	[651,867,705,856]	4	hSpCas9	negative selection	6325276
15518249	15518272	1	-	27260156	EW8	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.0916477517723093	[472]	[335,506,349,441]	1	hSpCas9	negative selection	6382247
15506019	15506042	1	+	27260156	EW8	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.48828644794542875	[195]	[320,177,230,169]	8	hSpCas9	negative selection	6382248
15518154	15518177	1	+	27260156	EW8	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.12123616148819436	[384]	[367,392,249,363]	2	hSpCas9	negative selection	6382249
15507002	15507025	1	-	27260156	EW8	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.21228258377095965	[127]	[281,99,44,83]	4	hSpCas9	negative selection	6446525
15506959	15506982	1	+	27260156	EW8	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.15028571427885418	[678]	[613,404,372,622]	-3	hSpCas9	negative selection	6446526
15505989	15506012	1	-	27260156	EW8	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.22772747152802408	[622]	[620,498,709,515]	4	hSpCas9	negative selection	6446527
15518249	15518272	1	-	27260156	CORL105	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.3904534954101008	[472]	[606,638,782,879]	7	hSpCas9	negative selection	6503498
15506019	15506042	1	+	27260156	CORL105	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.1094574440877698	[195]	[222,231,238,293]	2	hSpCas9	negative selection	6503499
15518154	15518177	1	+	27260156	CORL105	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.5678523698608944	[384]	[760,594,668,651]	9	hSpCas9	negative selection	6503500
15507002	15507025	1	-	27260156	CORL105	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.3595858023691343	[127]	[234,185,218,134]	6	hSpCas9	negative selection	6567776
15506959	15506982	1	+	27260156	CORL105	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.19157994328006162	[678]	[731,707,663,675]	-4	hSpCas9	negative selection	6567777
15505989	15506012	1	-	27260156	CORL105	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.2381069244206151	[622]	[786,779,1047,853]	4	hSpCas9	negative selection	6567778
15518249	15518272	1	-	27260156	HS294T	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	-0.04623891483731201	[472]	[170,165,153,225]	0	hSpCas9	negative selection	6624749
15506019	15506042	1	+	27260156	HS294T	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.3745797081779296	[195]	[126,97,75,86]	5	hSpCas9	negative selection	6624750
15518154	15518177	1	+	27260156	HS294T	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.242361861329287	[384]	[140,132,146,309]	3	hSpCas9	negative selection	6624751
15507002	15507025	1	-	27260156	HS294T	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.5674911364669488	[127]	[115,60,55,52]	7	hSpCas9	negative selection	6689027
15506959	15506982	1	+	27260156	HS294T	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.6572996336671364	[678]	[122,116,210,230]	-7	hSpCas9	negative selection	6689028
15505989	15506012	1	-	27260156	HS294T	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.31887355326357314	[622]	[439,314,194,223]	4	hSpCas9	negative selection	6689029
15518249	15518272	1	-	27260156	HCC44	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.4736571085859677	[472]	[610,808,1030,548]	7	hSpCas9	negative selection	6746000
15506019	15506042	1	+	27260156	HCC44	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.22171227561407902	[195]	[321,176,138,127]	-4	hSpCas9	negative selection	6746001
15518154	15518177	1	+	27260156	HCC44	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.01034764715593367	[384]	[516,401,412,426]	0	hSpCas9	negative selection	6746002
15507002	15507025	1	-	27260156	HCC44	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.35736703470248665	[127]	[275,149,104,207]	6	hSpCas9	negative selection	6810278
15506959	15506982	1	+	27260156	HCC44	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	0.06684975096453716	[678]	[743,807,907,763]	1	hSpCas9	negative selection	6810279
15505989	15506012	1	-	27260156	HCC44	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.28279908938393483	[622]	[779,766,976,921]	4	hSpCas9	negative selection	6810280
15518249	15518272	1	-	27260156	G402	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.6415566771383898	[472]	[1043,564,851,1126]	7	hSpCas9	negative selection	6867251
15506019	15506042	1	+	27260156	G402	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.7840808607703855	[195]	[259,214,91,15]	-7	hSpCas9	negative selection	6867252
15518154	15518177	1	+	27260156	G402	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.5192375549925833	[384]	[724,810,284,874]	6	hSpCas9	negative selection	6867253
15507002	15507025	1	-	27260156	G402	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.9965276205096316	[127]	[421,340,295,208]	9	hSpCas9	negative selection	6931529
15506959	15506982	1	+	27260156	G402	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.5290162725438817	[678]	[471,483,669,644]	-6	hSpCas9	negative selection	6931530
15505989	15506012	1	-	27260156	G402	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	1.1237443529629751	[622]	[1688,1576,2104,1267]	9	hSpCas9	negative selection	6931531
15518249	15518272	1	-	27260156	L33	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.07725688759374268	[472]	[586,152,328,509]	1	hSpCas9	negative selection	6988502
15506019	15506042	1	+	27260156	L33	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.37846196703720203	[195]	[221,104,171,267]	7	hSpCas9	negative selection	6988503
15518154	15518177	1	+	27260156	L33	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.2759207265287035	[384]	[428,175,278,561]	6	hSpCas9	negative selection	6988504
15507002	15507025	1	-	27260156	L33	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	-0.7058106520911043	[127]	[48,35,86,39]	-9	hSpCas9	negative selection	7052780
15506959	15506982	1	+	27260156	L33	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.11429270629581889	[678]	[567,329,355,570]	-3	hSpCas9	negative selection	7052781
15505989	15506012	1	-	27260156	L33	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	-0.1221257930626724	[622]	[552,226,352,620]	-3	hSpCas9	negative selection	7052782
15518249	15518272	1	-	27260156	K562	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.6292928717500845	[472]	[726,600,675,599]	7	hSpCas9	negative selection	7109753
15506019	15506042	1	+	27260156	K562	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.6269416436519577	[195]	[245,561,190,106]	7	hSpCas9	negative selection	7109754
15518154	15518177	1	+	27260156	K562	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.7468380246269322	[384]	[445,406,460,916]	8	hSpCas9	negative selection	7109755
15507002	15507025	1	-	27260156	K562	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	-0.0785868992687091	[127]	[175,37,102,113]	-1	hSpCas9	negative selection	7174031
15506959	15506982	1	+	27260156	K562	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.4717177670335897	[678]	[457,493,493,309]	-5	hSpCas9	negative selection	7174032
15505989	15506012	1	-	27260156	K562	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.14266741418157047	[622]	[745,647,486,574]	1	hSpCas9	negative selection	7174033
15518249	15518272	1	-	27260156	HT29	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.4853137593947873	[472]	[893,989,874,513]	8	hSpCas9	negative selection	7231004
15506019	15506042	1	+	27260156	HT29	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.07720867643707385	[195]	[268,284,200,162]	-2	hSpCas9	negative selection	7231005
15518154	15518177	1	+	27260156	HT29	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.3041342713201497	[384]	[583,737,516,492]	6	hSpCas9	negative selection	7231006
15507002	15507025	1	-	27260156	HT29	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.38703559948975674	[127]	[155,255,284,125]	7	hSpCas9	negative selection	7295282
15506959	15506982	1	+	27260156	HT29	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.3297281294591888	[678]	[838,660,608,541]	-6	hSpCas9	negative selection	7295283
15505989	15506012	1	-	27260156	HT29	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.269545177622744	[622]	[876,930,996,846]	5	hSpCas9	negative selection	7295284
15518249	15518272	1	-	27260156	MHHES1	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.3712508122470097	[472]	[828,634,496,769]	6	hSpCas9	negative selection	7352255
15506019	15506042	1	+	27260156	MHHES1	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.04294922100039544	[195]	[214,219,199,216]	-1	hSpCas9	negative selection	7352256
15518154	15518177	1	+	27260156	MHHES1	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.024091529788043076	[384]	[661,444,427,282]	0	hSpCas9	negative selection	7352257
15507002	15507025	1	-	27260156	MHHES1	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.16526903027608864	[127]	[84,162,243,145]	3	hSpCas9	negative selection	7416533
15506959	15506982	1	+	27260156	MHHES1	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.7183057835333012	[678]	[676,529,338,358]	-8	hSpCas9	negative selection	7416534
15505989	15506012	1	-	27260156	MHHES1	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.3348489447628251	[622]	[967,1162,922,576]	6	hSpCas9	negative selection	7416535
15518249	15518272	1	-	27260156	MEWO	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.2637187747046582	[472]	[524,427,639]	6	hSpCas9	negative selection	7473506
15506019	15506042	1	+	27260156	MEWO	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.04006547344048683	[195]	[293,186,104]	0	hSpCas9	negative selection	7473507
15518154	15518177	1	+	27260156	MEWO	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.008096926444960961	[384]	[380,405,302]	0	hSpCas9	negative selection	7473508
15507002	15507025	1	-	27260156	MEWO	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	-0.00017627935393949024	[127]	[123,121,113]	0	hSpCas9	negative selection	7537784
15506959	15506982	1	+	27260156	MEWO	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	0.027983403651403504	[678]	[791,622,555]	0	hSpCas9	negative selection	7537785
15505989	15506012	1	-	27260156	MEWO	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.27765155336438374	[622]	[782,562,788]	6	hSpCas9	negative selection	7537786
15518249	15518272	1	-	27260156	LNCAPCLONEFGC	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.46037792243346226	[472]	[503,587,565,697]	7	hSpCas9	negative selection	7594757
15506019	15506042	1	+	27260156	LNCAPCLONEFGC	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.2853339110415406	[195]	[182,183,302,210]	4	hSpCas9	negative selection	7594758
15518154	15518177	1	+	27260156	LNCAPCLONEFGC	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.5895456245489932	[384]	[449,479,785,425]	8	hSpCas9	negative selection	7594759
15507002	15507025	1	-	27260156	LNCAPCLONEFGC	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.4535437754520393	[127]	[146,130,137,217]	7	hSpCas9	negative selection	7659035
15506959	15506982	1	+	27260156	LNCAPCLONEFGC	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	0.0003879354941498381	[678]	[781,628,369,638]	0	hSpCas9	negative selection	7659036
15505989	15506012	1	-	27260156	LNCAPCLONEFGC	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.5676657514904838	[622]	[774,680,912,998]	8	hSpCas9	negative selection	7659037
15518249	15518272	1	-	27260156	PANC0327	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.2395740768211391	[472]	[475,481,376,648]	3	hSpCas9	negative selection	7716008
15506019	15506042	1	+	27260156	PANC0327	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.41735467439049734	[195]	[348,110,139,354]	6	hSpCas9	negative selection	7716009
15518154	15518177	1	+	27260156	PANC0327	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	-0.03063597034496679	[384]	[373,392,368,198]	0	hSpCas9	negative selection	7716010
15507002	15507025	1	-	27260156	PANC0327	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.04467628609512908	[127]	[69,171,51,163]	0	hSpCas9	negative selection	7780286
15506959	15506982	1	+	27260156	PANC0327	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.14538822943170615	[678]	[661,526,466,536]	-2	hSpCas9	negative selection	7780287
15505989	15506012	1	-	27260156	PANC0327	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.34939360201774716	[622]	[820,627,908,481]	5	hSpCas9	negative selection	7780288
15518249	15518272	1	-	27260156	NCIH2009	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.3370328170361721	[472]	[954,924,644]	4	hSpCas9	negative selection	7837259
15506019	15506042	1	+	27260156	NCIH2009	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	1.334416203208305	[195]	[534,621,883]	9	hSpCas9	negative selection	7837260
15518154	15518177	1	+	27260156	NCIH2009	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.28836469713398505	[384]	[765,557,668]	4	hSpCas9	negative selection	7837261
15507002	15507025	1	-	27260156	NCIH2009	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.6686249294900228	[127]	[394,240,238]	8	hSpCas9	negative selection	7901537
15506959	15506982	1	+	27260156	NCIH2009	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	0.14180520469620228	[678]	[978,980,1165]	2	hSpCas9	negative selection	7901538
15505989	15506012	1	-	27260156	NCIH2009	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.3459257581439733	[622]	[1117,846,1358]	5	hSpCas9	negative selection	7901539
15518249	15518272	1	-	27260156	NCIH1373	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	1.0940894863427018	[472]	[1623,659,679,454]	9	hSpCas9	negative selection	7958510
15506019	15506042	1	+	27260156	NCIH1373	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.10367711430834015	[195]	[123,103,482,23]	-1	hSpCas9	negative selection	7958511
15518154	15518177	1	+	27260156	NCIH1373	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.30389432071505773	[384]	[526,355,575,182]	3	hSpCas9	negative selection	7958512
15507002	15507025	1	-	27260156	NCIH1373	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.4736129846402013	[127]	[465,67,61,68]	4	hSpCas9	negative selection	8022788
15506959	15506982	1	+	27260156	NCIH1373	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.4153763682751632	[678]	[622,586,684,98]	-4	hSpCas9	negative selection	8022789
15505989	15506012	1	-	27260156	NCIH1373	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.8865099317989771	[622]	[1993,541,1268,409]	8	hSpCas9	negative selection	8022790
15518249	15518272	1	-	27260156	PATU8902	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.45772658202685546	[472]	[807,897,651,1376]	5	hSpCas9	negative selection	8079761
15506019	15506042	1	+	27260156	PATU8902	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.7657060386610861	[195]	[184,142,63,288]	-6	hSpCas9	negative selection	8079762
15518154	15518177	1	+	27260156	PATU8902	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.08821092378319698	[384]	[542,712,374,712]	0	hSpCas9	negative selection	8079763
15507002	15507025	1	-	27260156	PATU8902	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	1.1537872186542946	[127]	[420,263,525,329]	9	hSpCas9	negative selection	8144039
15506959	15506982	1	+	27260156	PATU8902	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.5038743842807615	[678]	[889,721,588,452]	-5	hSpCas9	negative selection	8144040
15505989	15506012	1	-	27260156	PATU8902	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.40977446799496076	[622]	[1260,817,1096,1475]	4	hSpCas9	negative selection	8144041
15518249	15518272	1	-	27260156	PANC1	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.3430115567564799	[472]	[553,431,475,563]	5	hSpCas9	negative selection	8201012
15506019	15506042	1	+	27260156	PANC1	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.22468351574450685	[195]	[116,138,208,113]	-4	hSpCas9	negative selection	8201013
15518154	15518177	1	+	27260156	PANC1	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.09356802410002343	[384]	[365,416,349,294]	1	hSpCas9	negative selection	8201014
15507002	15507025	1	-	27260156	PANC1	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.9584017393923093	[127]	[183,93,408,151]	9	hSpCas9	negative selection	8265290
15506959	15506982	1	+	27260156	PANC1	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.46615056237497227	[678]	[446,408,418,405]	-6	hSpCas9	negative selection	8265291
15505989	15506012	1	-	27260156	PANC1	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.2694747806265073	[622]	[700,867,690,395]	4	hSpCas9	negative selection	8265292
15518249	15518272	1	-	27260156	PANC0813	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.6385035713905418	[472]	[1506,730,712,581]	8	hSpCas9	negative selection	8322263
15506019	15506042	1	+	27260156	PANC0813	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.3272993700154482	[195]	[308,337,246,263]	5	hSpCas9	negative selection	8322264
15518154	15518177	1	+	27260156	PANC0813	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.5137422358192418	[384]	[486,422,791,853]	7	hSpCas9	negative selection	8322265
15507002	15507025	1	-	27260156	PANC0813	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.18128825977648266	[127]	[177,175,169,158]	3	hSpCas9	negative selection	8386541
15506959	15506982	1	+	27260156	PANC0813	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.22324764990597	[678]	[782,711,674,576]	-4	hSpCas9	negative selection	8386542
15505989	15506012	1	-	27260156	PANC0813	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.30742131861399	[622]	[1133,893,757,857]	5	hSpCas9	negative selection	8386543
15518249	15518272	1	-	27260156	RDES	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.4887946346617168	[472]	[662,608,894,929]	7	hSpCas9	negative selection	8443514
15506019	15506042	1	+	27260156	RDES	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.011037798437310231	[195]	[183,212,273,245]	0	hSpCas9	negative selection	8443515
15518154	15518177	1	+	27260156	RDES	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.12102284475305261	[384]	[360,477,385,750]	2	hSpCas9	negative selection	8443516
15507002	15507025	1	-	27260156	RDES	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.09079318177106566	[127]	[134,193,129,163]	1	hSpCas9	negative selection	8507792
15506959	15506982	1	+	27260156	RDES	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.8951016914297919	[678]	[394,388,419,478]	-9	hSpCas9	negative selection	8507793
15505989	15506012	1	-	27260156	RDES	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.6087621099904654	[622]	[787,939,1263,1496]	8	hSpCas9	negative selection	8507794
15518249	15518272	1	-	27260156	PC3	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.08052629015640005	[472]	[284,350,1248,458]	1	hSpCas9	negative selection	8564765
15506019	15506042	1	+	27260156	PC3	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.26384207456322073	[195]	[132,258,378,245]	6	hSpCas9	negative selection	8564766
15518154	15518177	1	+	27260156	PC3	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	-0.04622361664787855	[384]	[271,290,800,293]	-1	hSpCas9	negative selection	8564767
15507002	15507025	1	-	27260156	PC3	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	-0.42693887367428474	[127]	[42,185,94,63]	-7	hSpCas9	negative selection	8629043
15506959	15506982	1	+	27260156	PC3	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.1170852074888547	[678]	[344,567,1147,714]	-3	hSpCas9	negative selection	8629044
15505989	15506012	1	-	27260156	PC3	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.22035572286239036	[622]	[568,734,1084,620]	5	hSpCas9	negative selection	8629045
15518249	15518272	1	-	27260156	PATU8988T	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.15474028091349523	[472]	[414,499,578,541]	2	hSpCas9	negative selection	8686016
15506019	15506042	1	+	27260156	PATU8988T	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.2108934132844491	[195]	[240,189,252,186]	3	hSpCas9	negative selection	8686017
15518154	15518177	1	+	27260156	PATU8988T	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.5475395723747971	[384]	[611,423,574,552]	8	hSpCas9	negative selection	8686018
15507002	15507025	1	-	27260156	PATU8988T	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.8049355301923975	[127]	[252,324,124,168]	9	hSpCas9	negative selection	8750294
15506959	15506982	1	+	27260156	PATU8988T	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.5212225954183747	[678]	[483,428,396,521]	-7	hSpCas9	negative selection	8750295
15505989	15506012	1	-	27260156	PATU8988T	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.19078498293100787	[622]	[591,617,702,840]	3	hSpCas9	negative selection	8750296
15518249	15518272	1	-	27260156	T47D	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.2512252767406834	[472]	[619,599,616,795]	5	hSpCas9	negative selection	8807267
15506019	15506042	1	+	27260156	T47D	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.08273726800401371	[195]	[273,163,217,320]	1	hSpCas9	negative selection	8807268
15518154	15518177	1	+	27260156	T47D	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.17721047250064836	[384]	[468,486,505,569]	4	hSpCas9	negative selection	8807269
15507002	15507025	1	-	27260156	T47D	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.4659421637170744	[127]	[205,160,252,206]	8	hSpCas9	negative selection	8871545
15506959	15506982	1	+	27260156	T47D	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.2702809083154974	[678]	[741,540,695,653]	-5	hSpCas9	negative selection	8871546
15505989	15506012	1	-	27260156	T47D	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.14125261742970607	[622]	[728,739,819,920]	3	hSpCas9	negative selection	8871547
15518249	15518272	1	-	27260156	SU8686	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.4877020445416779	[472]	[481,659,685,848]	7	hSpCas9	negative selection	8928518
15506019	15506042	1	+	27260156	SU8686	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.3320899095020414	[195]	[138,302,292,247]	5	hSpCas9	negative selection	8928519
15518154	15518177	1	+	27260156	SU8686	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.00382565883309266	[384]	[349,325,488,375]	0	hSpCas9	negative selection	8928520
15507002	15507025	1	-	27260156	SU8686	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	-0.25421410343492346	[127]	[130,110,55,124]	-4	hSpCas9	negative selection	8992796
15506959	15506982	1	+	27260156	SU8686	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.45429731325966416	[678]	[334,424,732,503]	-6	hSpCas9	negative selection	8992797
15505989	15506012	1	-	27260156	SU8686	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.18841805567466385	[622]	[611,541,728,1008]	3	hSpCas9	negative selection	8992798
15518249	15518272	1	-	27260156	SKES1	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.21502668116440737	[472]	[425,600,695,459]	4	hSpCas9	negative selection	9049769
15506019	15506042	1	+	27260156	SKES1	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.054859710241329296	[195]	[169,268,192,183]	1	hSpCas9	negative selection	9049770
15518154	15518177	1	+	27260156	SKES1	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.08018726676673307	[384]	[408,394,473,346]	1	hSpCas9	negative selection	9049771
15507002	15507025	1	-	27260156	SKES1	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	-0.023617841043985788	[127]	[150,172,69,117]	0	hSpCas9	negative selection	9114047
15506959	15506982	1	+	27260156	SKES1	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.41313573978204465	[678]	[622,598,437,408]	-7	hSpCas9	negative selection	9114048
15505989	15506012	1	-	27260156	SKES1	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.1924021298796894	[622]	[840,897,516,629]	4	hSpCas9	negative selection	9114049
15518249	15518272	1	-	27260156	TOV112D	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.23813973379516973	[472]	[375,986,398,561]	4	hSpCas9	negative selection	9171020
15506019	15506042	1	+	27260156	TOV112D	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.1932144038157524	[195]	[45,182,179,266]	-4	hSpCas9	negative selection	9171021
15518154	15518177	1	+	27260156	TOV112D	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.029513529990590703	[384]	[287,290,476,480]	0	hSpCas9	negative selection	9171022
15507002	15507025	1	-	27260156	TOV112D	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.3510801818276128	[127]	[195,166,188,106]	6	hSpCas9	negative selection	9235298
15506959	15506982	1	+	27260156	TOV112D	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.49302329261636235	[678]	[460,500,506,465]	-7	hSpCas9	negative selection	9235299
15505989	15506012	1	-	27260156	TOV112D	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.5537036636072289	[622]	[1119,799,861,869]	8	hSpCas9	negative selection	9235300
15518249	15518272	1	-	27260156	TC71	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.24629096811142134	[472]	[533,736,548,587]	6	hSpCas9	negative selection	9292271
15506019	15506042	1	+	27260156	TC71	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	-0.12113622207824637	[195]	[118,136,252,267]	-3	hSpCas9	negative selection	9292272
15518154	15518177	1	+	27260156	TC71	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.2863087067852859	[384]	[529,430,497,556]	7	hSpCas9	negative selection	9292273
15507002	15507025	1	-	27260156	TC71	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.19871942858331804	[127]	[181,151,127,168]	5	hSpCas9	negative selection	9356549
15506959	15506982	1	+	27260156	TC71	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.4415583967816612	[678]	[499,555,551,535]	-8	hSpCas9	negative selection	9356550
15505989	15506012	1	-	27260156	TC71	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.12208594648579663	[622]	[601,831,620,866]	3	hSpCas9	negative selection	9356551
15518249	15518272	1	-	27260156	TC32	viability	CTTCGTTTCTGCGAACTAACAGG	CASP9	ENSG00000132906	0.3429991205421604	[472]	[399,514,850,542]	6	hSpCas9	negative selection	9413522
15506019	15506042	1	+	27260156	TC32	viability	CGCAGCAGTCCAGAGCACCGTGG	CASP9	ENSG00000132906	0.1852135420335259	[195]	[159,166,290,245]	3	hSpCas9	negative selection	9413523
15518154	15518177	1	+	27260156	TC32	viability	GTTTCCGGTCTGAGAACCTCTGG	CASP9	ENSG00000132906	0.3579767593204358	[384]	[459,378,520,510]	6	hSpCas9	negative selection	9413524
15507002	15507025	1	-	27260156	TC32	viability	GTGAACTTCTGCCGTGAGTCCGG	CASP9	ENSG00000132906	0.4803331513911775	[127]	[121,101,303,189]	7	hSpCas9	negative selection	9477800
15506959	15506982	1	+	27260156	TC32	viability	CAACTTCTCACAGTCGATGTTGG	CASP9	ENSG00000132906	-0.6068121987700252	[678]	[381,304,510,522]	-8	hSpCas9	negative selection	9477801
15505989	15506012	1	-	27260156	TC32	viability	CATTCTCTCTCACGGCTGTCAGG	CASP9	ENSG00000132906	0.5871753804022739	[622]	[750,758,1061,991]	8	hSpCas9	negative selection	9477802
15493882	15493905	1	+	27869803	HPAFII	viability after 27 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.05622260581480809	[385]	[270,160,NaN]	0	hSpCas9	negative selection	9529700
15495420	15495443	1	+	27869803	HPAFII	viability after 27 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.4054993096176598	[365]	[153,137,NaN]	-3	hSpCas9	negative selection	9529701
15504688	15504711	1	+	27869803	HPAFII	viability after 27 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.662637771796948	[224]	[47,96,NaN]	-5	hSpCas9	negative selection	9529719
15507031	15507054	1	+	27869803	HPAFII	viability after 27 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.72449624220399	[45]	[24,5,NaN]	-5	hSpCas9	negative selection	9529725
15518124	15518147	1	+	27869803	HPAFII	viability after 27 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-2.342278920368821	[234]	[1,42,NaN]	-8	hSpCas9	negative selection	9529737
15524188	15524211	1	-	27869803	HPAFII	viability after 27 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.8020453616682537	[403]	[141,104,NaN]	-5	hSpCas9	negative selection	9529738
15493882	15493905	1	+	27869803	HPAFII	viability after 15 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.7487659901925046	[385]	[384,160,NaN]	-7	hSpCas9	negative selection	9612149
15495420	15495443	1	+	27869803	HPAFII	viability after 15 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.5537751628655263	[365]	[246,280,NaN]	-5	hSpCas9	negative selection	9612150
15504688	15504711	1	+	27869803	HPAFII	viability after 15 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.4703655332041359	[224]	[213,149,NaN]	-5	hSpCas9	negative selection	9612168
15507031	15507054	1	+	27869803	HPAFII	viability after 15 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.341545925944843	[45]	[30,43,NaN]	-4	hSpCas9	negative selection	9612174
15518124	15518147	1	+	27869803	HPAFII	viability after 15 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-0.4580656584150561	[234]	[62,258,NaN]	-5	hSpCas9	negative selection	9612186
15524188	15524211	1	-	27869803	HPAFII	viability after 15 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.625855807586291	[403]	[326,252,NaN]	-6	hSpCas9	negative selection	9612187
15493882	15493905	1	+	27869803	ASPC1	viability after 36 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.027286945176429406	[731]	[166,310,258]	0	hSpCas9	negative selection	9694598
15495420	15495443	1	+	27869803	ASPC1	viability after 36 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.9931970407011355	[841]	[285,119,70]	-7	hSpCas9	negative selection	9694599
15504688	15504711	1	+	27869803	ASPC1	viability after 36 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.06420941537512248	[628]	[403,288,8]	0	hSpCas9	negative selection	9694617
15507031	15507054	1	+	27869803	ASPC1	viability after 36 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.18208718837806082	[135]	[10,119,0]	-2	hSpCas9	negative selection	9694623
15518124	15518147	1	+	27869803	ASPC1	viability after 36 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	0.5517589869604044	[525]	[273,98,397]	5	hSpCas9	negative selection	9694635
15524188	15524211	1	-	27869803	ASPC1	viability after 36 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.33564564177016987	[850]	[651,241,281]	3	hSpCas9	negative selection	9694636
15493882	15493905	1	+	27869803	PATU8988S	viability after 35 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.38810943398940456	[627]	[330,330,NaN]	4	hSpCas9	negative selection	9777047
15495420	15495443	1	+	27869803	PATU8988S	viability after 35 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.5268452289296414	[677]	[200,177,NaN]	-5	hSpCas9	negative selection	9777048
15504688	15504711	1	+	27869803	PATU8988S	viability after 35 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.12173844554572737	[569]	[206,214,NaN]	-1	hSpCas9	negative selection	9777066
15507031	15507054	1	+	27869803	PATU8988S	viability after 35 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	0.6056611719304785	[114]	[60,79,NaN]	6	hSpCas9	negative selection	9777072
15518124	15518147	1	+	27869803	PATU8988S	viability after 35 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-0.2487535220455295	[502]	[169,170,NaN]	-3	hSpCas9	negative selection	9777084
15524188	15524211	1	-	27869803	PATU8988S	viability after 35 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.7141099657155558	[718]	[493,455,NaN]	7	hSpCas9	negative selection	9777085
15493882	15493905	1	+	27869803	PATU8988S	viability after 31 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	-0.2232510904417488	[627]	[166,274,NaN]	-3	hSpCas9	negative selection	9859496
15495420	15495443	1	+	27869803	PATU8988S	viability after 31 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.7275196836412661	[677]	[135,197,NaN]	-7	hSpCas9	negative selection	9859497
15504688	15504711	1	+	27869803	PATU8988S	viability after 31 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	0.2665615909269702	[569]	[312,222,NaN]	3	hSpCas9	negative selection	9859515
15507031	15507054	1	+	27869803	PATU8988S	viability after 31 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.8523177869125371	[114]	[20,30,NaN]	-7	hSpCas9	negative selection	9859521
15518124	15518147	1	+	27869803	PATU8988S	viability after 31 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-0.506077755472356	[502]	[76,222,NaN]	-5	hSpCas9	negative selection	9859533
15524188	15524211	1	-	27869803	PATU8988S	viability after 31 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	0.7504584586635066	[718]	[469,497,NaN]	8	hSpCas9	negative selection	9859534
15493882	15493905	1	+	27869803	HPAFII	viability after 35 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	1.1550797808166782	[385]	[667,172,NaN]	7	hSpCas9	negative selection	9941945
15495420	15495443	1	+	27869803	HPAFII	viability after 35 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-0.3391853219924409	[365]	[137,155,NaN]	-2	hSpCas9	negative selection	9941946
15504688	15504711	1	+	27869803	HPAFII	viability after 35 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.32446207715511977	[224]	[18,171,NaN]	-2	hSpCas9	negative selection	9941964
15507031	15507054	1	+	27869803	HPAFII	viability after 35 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-0.9631790325898191	[45]	[18,3,NaN]	-5	hSpCas9	negative selection	9941970
15518124	15518147	1	+	27869803	HPAFII	viability after 35 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-2.5859634494802903	[234]	[0,40,NaN]	-8	hSpCas9	negative selection	9941982
15524188	15524211	1	-	27869803	HPAFII	viability after 35 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-1.169519382060123	[403]	[57,127,NaN]	-6	hSpCas9	negative selection	9941983
15493882	15493905	1	+	27869803	HPAFII	viability after 31 days	CAGCACTCACCCTAAGCAGGAGG	CASP9	ENSG00000132906	0.6302535685519429	[385]	[464,193,NaN]	4	hSpCas9	negative selection	10024394
15495420	15495443	1	+	27869803	HPAFII	viability after 31 days	TGGAGGCCACCTCAAACCCATGG	CASP9	ENSG00000132906	-1.1091142704514592	[365]	[88,101,NaN]	-6	hSpCas9	negative selection	10024395
15504688	15504711	1	+	27869803	HPAFII	viability after 31 days	ACAATCTTCTCGACCGACACAGG	CASP9	ENSG00000132906	-0.3616050097306387	[224]	[70,127,NaN]	-2	hSpCas9	negative selection	10024413
15507031	15507054	1	+	27869803	HPAFII	viability after 31 days	GATAATGAGGCAGTGGCCACAGG	CASP9	ENSG00000132906	-1.599095445631494	[45]	[8,7,NaN]	-7	hSpCas9	negative selection	10024419
15518124	15518147	1	+	27869803	HPAFII	viability after 31 days	CCTCCAGAACCAATGTCCACTGG	CASP9	ENSG00000132906	-2.6236068553759573	[234]	[7,35,NaN]	-8	hSpCas9	negative selection	10024431
15524188	15524211	1	-	27869803	HPAFII	viability after 31 days	GCTACTCGCCATGGACGAAGCGG	CASP9	ENSG00000132906	-0.7342741381623962	[403]	[153,116,NaN]	-5	hSpCas9	negative selection	10024432
15506971	15506994	1	+	28162770	P31FUJ	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.0225582735339942	[376]	[449]	0	hSpCas9	negative selection	10126265
15506916	15506939	1	-	28162770	P31FUJ	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.37815550483972205	[329]	[503]	4	hSpCas9	negative selection	10126266
15506036	15506059	1	-	28162770	P31FUJ	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	0.08035568084525158	[197]	[245]	0	hSpCas9	negative selection	10126267
15518140	15518163	1	-	28162770	P31FUJ	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	0.48848176751955785	[36]	[60]	5	hSpCas9	negative selection	10126268
15518124	15518147	1	-	28162770	P31FUJ	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	0.5577444299566716	[110]	[191]	6	hSpCas9	negative selection	10126269
15506898	15506921	1	-	28162770	P31FUJ	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.2741577843055044	[303]	[431]	3	hSpCas9	negative selection	10126270
15504648	15504671	1	-	28162770	P31FUJ	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-0.35626589164550204	[316]	[290]	-3	hSpCas9	negative selection	10126271
15495426	15495449	1	-	28162770	P31FUJ	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.1250883871141254	[128]	[138]	-1	hSpCas9	negative selection	10126272
15495352	15495375	1	+	28162770	P31FUJ	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-0.9946424672196144	[38]	[22]	-6	hSpCas9	negative selection	10126273
15507024	15507047	1	+	28162770	P31FUJ	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.4010251197104566	[715]	[1110]	4	hSpCas9	negative selection	10126274
15506971	15506994	1	+	28162770	TF1	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	NaN	[NaN]	[316]	1	hSpCas9	negative selection	10295631
15506916	15506939	1	-	28162770	TF1	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	NaN	[NaN]	[377]	1	hSpCas9	negative selection	10295632
15506036	15506059	1	-	28162770	TF1	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10295633
15518140	15518163	1	-	28162770	TF1	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10295634
15518124	15518147	1	-	28162770	TF1	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10295635
15506898	15506921	1	-	28162770	TF1	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	NaN	[NaN]	[298]	1	hSpCas9	negative selection	10295636
15504648	15504671	1	-	28162770	TF1	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10295637
15495426	15495449	1	-	28162770	TF1	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	NaN	[NaN]	[63]	1	hSpCas9	negative selection	10295638
15495352	15495375	1	+	28162770	TF1	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10295639
15507024	15507047	1	+	28162770	TF1	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	NaN	[NaN]	[869]	1	hSpCas9	negative selection	10295640
15506971	15506994	1	+	28162770	SKM1	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.404213587727127	[130]	[174]	-3	hSpCas9	negative selection	10464997
15506916	15506939	1	-	28162770	SKM1	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.2293451819782148	[68]	[142]	2	hSpCas9	negative selection	10464998
15506036	15506059	1	-	28162770	SKM1	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-0.9628642338618553	[85]	[77]	-6	hSpCas9	negative selection	10464999
15518140	15518163	1	-	28162770	SKM1	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	2.315501825727929	[9]	[87]	9	hSpCas9	negative selection	10465000
15518124	15518147	1	-	28162770	SKM1	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	1.0011205398939151	[25]	[91]	8	hSpCas9	negative selection	10465001
15506898	15506921	1	-	28162770	SKM1	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.09961040329327853	[103]	[196]	0	hSpCas9	negative selection	10465002
15504648	15504671	1	-	28162770	SKM1	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-0.2005133212757354	[51]	[79]	-2	hSpCas9	negative selection	10465003
15495426	15495449	1	-	28162770	SKM1	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.5071283606685936	[40]	[50]	-4	hSpCas9	negative selection	10465004
15495352	15495375	1	+	28162770	SKM1	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-1.5224414161630975	[12]	[7]	-7	hSpCas9	negative selection	10465005
15507024	15507047	1	+	28162770	SKM1	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.7297939387639514	[175]	[515]	7	hSpCas9	negative selection	10465006
15506971	15506994	1	+	28162770	SKM1	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.404213587727127	[130]	[174]	-3	hSpCas9	negative selection	10634363
15506916	15506939	1	-	28162770	SKM1	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.2293451819782148	[68]	[142]	2	hSpCas9	negative selection	10634364
15506036	15506059	1	-	28162770	SKM1	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-0.9628642338618553	[85]	[77]	-6	hSpCas9	negative selection	10634365
15518140	15518163	1	-	28162770	SKM1	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	2.315501825727929	[9]	[87]	9	hSpCas9	negative selection	10634366
15518124	15518147	1	-	28162770	SKM1	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	1.0011205398939151	[25]	[91]	8	hSpCas9	negative selection	10634367
15506898	15506921	1	-	28162770	SKM1	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.09961040329327853	[103]	[196]	0	hSpCas9	negative selection	10634368
15504648	15504671	1	-	28162770	SKM1	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-0.2005133212757354	[51]	[79]	-2	hSpCas9	negative selection	10634369
15495426	15495449	1	-	28162770	SKM1	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.5071283606685936	[40]	[50]	-4	hSpCas9	negative selection	10634370
15495352	15495375	1	+	28162770	SKM1	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-1.5224414161630975	[12]	[7]	-7	hSpCas9	negative selection	10634371
15507024	15507047	1	+	28162770	SKM1	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.7297939387639514	[175]	[515]	7	hSpCas9	negative selection	10634372
15506971	15506994	1	+	28162770	PL21	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.4713487299556428	[480]	[150]	-3	hSpCas9	negative selection	10803729
15506916	15506939	1	-	28162770	PL21	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	1.1762928725349522	[182]	[179]	8	hSpCas9	negative selection	10803730
15506036	15506059	1	-	28162770	PL21	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	0.4015195024093244	[246]	[141]	3	hSpCas9	negative selection	10803731
15518140	15518163	1	-	28162770	PL21	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	-0.15349734012538052	[45]	[17]	-1	hSpCas9	negative selection	10803732
15518124	15518147	1	-	28162770	PL21	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	-1.0093137511396297	[110]	[23]	-6	hSpCas9	negative selection	10803733
15506898	15506921	1	-	28162770	PL21	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.22271746246452984	[316]	[160]	2	hSpCas9	negative selection	10803734
15504648	15504671	1	-	28162770	PL21	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-0.006311262978106455	[209]	[90]	0	hSpCas9	negative selection	10803735
15495426	15495449	1	-	28162770	PL21	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	1.6486001153056145	[95]	[130]	9	hSpCas9	negative selection	10803736
15495352	15495375	1	+	28162770	PL21	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-0.7473929656165441	[26]	[6]	-5	hSpCas9	negative selection	10803737
15507024	15507047	1	+	28162770	PL21	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	-0.2351868073307024	[548]	[202]	-2	hSpCas9	negative selection	10803738
15506971	15506994	1	+	28162770	P31FUJ	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.0225582735339942	[376]	[449]	0	hSpCas9	negative selection	10973095
15506916	15506939	1	-	28162770	P31FUJ	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.37815550483972205	[329]	[503]	4	hSpCas9	negative selection	10973096
15506036	15506059	1	-	28162770	P31FUJ	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	0.08035568084525158	[197]	[245]	0	hSpCas9	negative selection	10973097
15518140	15518163	1	-	28162770	P31FUJ	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	0.48848176751955785	[36]	[60]	5	hSpCas9	negative selection	10973098
15518124	15518147	1	-	28162770	P31FUJ	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	0.5577444299566716	[110]	[191]	6	hSpCas9	negative selection	10973099
15506898	15506921	1	-	28162770	P31FUJ	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.2741577843055044	[303]	[431]	3	hSpCas9	negative selection	10973100
15504648	15504671	1	-	28162770	P31FUJ	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-0.35626589164550204	[316]	[290]	-3	hSpCas9	negative selection	10973101
15495426	15495449	1	-	28162770	P31FUJ	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.1250883871141254	[128]	[138]	-1	hSpCas9	negative selection	10973102
15495352	15495375	1	+	28162770	P31FUJ	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-0.9946424672196144	[38]	[22]	-6	hSpCas9	negative selection	10973103
15507024	15507047	1	+	28162770	P31FUJ	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.4010251197104566	[715]	[1110]	4	hSpCas9	negative selection	10973104
15506971	15506994	1	+	28162770	OCIAML5	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.19252358016007343	[222]	[459]	1	hSpCas9	negative selection	11142461
15506916	15506939	1	-	28162770	OCIAML5	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	1.1288246061882985	[151]	[599]	8	hSpCas9	negative selection	11142462
15506036	15506059	1	-	28162770	OCIAML5	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-1.3705336597982463	[158]	[110]	-7	hSpCas9	negative selection	11142463
15518140	15518163	1	-	28162770	OCIAML5	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	0.23039558932797588	[16]	[35]	2	hSpCas9	negative selection	11142464
15518124	15518147	1	-	28162770	OCIAML5	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	-0.15904432428538773	[59]	[96]	-1	hSpCas9	negative selection	11142465
15506898	15506921	1	-	28162770	OCIAML5	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.49999349536451987	[198]	[507]	4	hSpCas9	negative selection	11142466
15504648	15504671	1	-	28162770	OCIAML5	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-1.4541025849440945	[169]	[111]	-7	hSpCas9	negative selection	11142467
15495426	15495449	1	-	28162770	OCIAML5	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.6170465411997996	[129]	[152]	-4	hSpCas9	negative selection	11142468
15495352	15495375	1	+	28162770	OCIAML5	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-1.7265356887801384	[21]	[11]	-7	hSpCas9	negative selection	11142469
15507024	15507047	1	+	28162770	OCIAML5	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.18435683738587683	[351]	[721]	1	hSpCas9	negative selection	11142470
15506971	15506994	1	+	28162770	EOL1	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.3324783843551187	[813]	[539]	3	hSpCas9	negative selection	11311827
15506916	15506939	1	-	28162770	EOL1	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	-0.4295949481819975	[316]	[123]	-3	hSpCas9	negative selection	11311828
15506036	15506059	1	-	28162770	EOL1	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-2.2238440683221365	[531]	[59]	-8	hSpCas9	negative selection	11311829
15518140	15518163	1	-	28162770	EOL1	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	0.3196857134116735	[72]	[47]	3	hSpCas9	negative selection	11311830
15518124	15518147	1	-	28162770	EOL1	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	0.022951475631529106	[169]	[90]	0	hSpCas9	negative selection	11311831
15506898	15506921	1	-	28162770	EOL1	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.0024144429765481368	[558]	[294]	0	hSpCas9	negative selection	11311832
15504648	15504671	1	-	28162770	EOL1	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-0.2119910613772311	[298]	[135]	-2	hSpCas9	negative selection	11311833
15495426	15495449	1	-	28162770	EOL1	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.02541154592986994	[169]	[87]	0	hSpCas9	negative selection	11311834
15495352	15495375	1	+	28162770	EOL1	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-0.8530598070930178	[23]	[6]	-5	hSpCas9	negative selection	11311835
15507024	15507047	1	+	28162770	EOL1	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.20443409564097115	[765]	[464]	1	hSpCas9	negative selection	11311836
15506971	15506994	1	+	28162770	MOLM13	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	1.126168559908656	[632]	[998]	8	hSpCas9	negative selection	11481193
15506916	15506939	1	-	28162770	MOLM13	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.8489067718909193	[353]	[460]	6	hSpCas9	negative selection	11481194
15506036	15506059	1	-	28162770	MOLM13	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-1.324818764548624	[342]	[98]	-6	hSpCas9	negative selection	11481195
15518140	15518163	1	-	28162770	MOLM13	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	0.4678893815445788	[51]	[51]	3	hSpCas9	negative selection	11481196
15518124	15518147	1	-	28162770	MOLM13	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	0.17484240664434558	[135]	[110]	1	hSpCas9	negative selection	11481197
15506898	15506921	1	-	28162770	MOLM13	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.3986821061903355	[426]	[406]	3	hSpCas9	negative selection	11481198
15504648	15504671	1	-	28162770	MOLM13	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-2.0756531917965964	[308]	[52]	-7	hSpCas9	negative selection	11481199
15495426	15495449	1	-	28162770	MOLM13	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.4526761509610162	[105]	[55]	-3	hSpCas9	negative selection	11481200
15495352	15495375	1	+	28162770	MOLM13	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-1.9013444281211398	[30]	[5]	-7	hSpCas9	negative selection	11481201
15507024	15507047	1	+	28162770	MOLM13	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.9067736227777905	[674]	[914]	7	hSpCas9	negative selection	11481202
15506971	15506994	1	+	28162770	HEL	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.5697593866432513	[668]	[635]	5	hSpCas9	negative selection	11650559
15506916	15506939	1	-	28162770	HEL	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.22929811765584257	[300]	[225]	1	hSpCas9	negative selection	11650560
15506036	15506059	1	-	28162770	HEL	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-0.3438406522373213	[320]	[161]	-2	hSpCas9	negative selection	11650561
15518140	15518163	1	-	28162770	HEL	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	-0.028638420538272147	[42]	[26]	0	hSpCas9	negative selection	11650562
15518124	15518147	1	-	28162770	HEL	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	0.5432031584494423	[134]	[125]	4	hSpCas9	negative selection	11650563
15506898	15506921	1	-	28162770	HEL	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.8602545330620531	[380]	[442]	7	hSpCas9	negative selection	11650564
15504648	15504671	1	-	28162770	HEL	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-0.4306343543298623	[241]	[114]	-3	hSpCas9	negative selection	11650565
15495426	15495449	1	-	28162770	HEL	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-1.1298506718965702	[122]	[35]	-6	hSpCas9	negative selection	11650566
15495352	15495375	1	+	28162770	HEL	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-0.3572611679996429	[31]	[15]	-2	hSpCas9	negative selection	11650567
15507024	15507047	1	+	28162770	HEL	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.8800546991727778	[631]	[744]	7	hSpCas9	negative selection	11650568
15506971	15506994	1	+	28162770	MV411	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.07971010504470888	[409]	[364]	0	hSpCas9	negative selection	11819925
15506916	15506939	1	-	28162770	MV411	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.5751020152192821	[250]	[314]	5	hSpCas9	negative selection	11819926
15506036	15506059	1	-	28162770	MV411	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	0.16582378522912322	[199]	[188]	1	hSpCas9	negative selection	11819927
15518140	15518163	1	-	28162770	MV411	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	-0.8305649612184975	[37]	[17]	-5	hSpCas9	negative selection	11819928
15518124	15518147	1	-	28162770	MV411	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	-0.5262865933935486	[105]	[61]	-4	hSpCas9	negative selection	11819929
15506898	15506921	1	-	28162770	MV411	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.12766019592921385	[363]	[334]	1	hSpCas9	negative selection	11819930
15504648	15504671	1	-	28162770	MV411	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-0.908480592665658	[204]	[91]	-6	hSpCas9	negative selection	11819931
15495426	15495449	1	-	28162770	MV411	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-1.1631947693760671	[108]	[40]	-6	hSpCas9	negative selection	11819932
15495352	15495375	1	+	28162770	MV411	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	0.24743755078277507	[18]	[18]	2	hSpCas9	negative selection	11819933
15507024	15507047	1	+	28162770	MV411	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.4444128822239044	[498]	[571]	4	hSpCas9	negative selection	11819934
15506971	15506994	1	+	28162770	MONOMAC1	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.18784767560489346	[312]	[314]	-2	hSpCas9	negative selection	11989291
15506916	15506939	1	-	28162770	MONOMAC1	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.07598164734686219	[167]	[202]	0	hSpCas9	negative selection	11989292
15506036	15506059	1	-	28162770	MONOMAC1	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-1.240891136648981	[166]	[80]	-7	hSpCas9	negative selection	11989293
15518140	15518163	1	-	28162770	MONOMAC1	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	-0.14973113228119717	[29]	[30]	-1	hSpCas9	negative selection	11989294
15518124	15518147	1	-	28162770	MONOMAC1	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	0.4121731999082797	[58]	[89]	4	hSpCas9	negative selection	11989295
15506898	15506921	1	-	28162770	MONOMAC1	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	-0.10127786425412277	[203]	[217]	-1	hSpCas9	negative selection	11989296
15504648	15504671	1	-	28162770	MONOMAC1	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-1.3169463107947503	[162]	[74]	-7	hSpCas9	negative selection	11989297
15495426	15495449	1	-	28162770	MONOMAC1	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.4784497822082022	[78]	[64]	-4	hSpCas9	negative selection	11989298
15495352	15495375	1	+	28162770	MONOMAC1	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-1.1970368470595534	[17]	[8]	-7	hSpCas9	negative selection	11989299
15507024	15507047	1	+	28162770	MONOMAC1	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	1.1910526133353767	[357]	[936]	9	hSpCas9	negative selection	11989300
15506971	15506994	1	+	28162770	OCIAML2	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	0.21022810270131376	[96]	[621]	2	hSpCas9	negative selection	12158657
15506916	15506939	1	-	28162770	OCIAML2	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	0.016816169564732752	[50]	[285]	0	hSpCas9	negative selection	12158658
15506036	15506059	1	-	28162770	OCIAML2	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	0.16495874854896297	[55]	[347]	1	hSpCas9	negative selection	12158659
15518140	15518163	1	-	28162770	OCIAML2	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	1.425534363773299	[8]	[133]	9	hSpCas9	negative selection	12158660
15518124	15518147	1	-	28162770	OCIAML2	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	-0.12013257815802791	[19]	[101]	-1	hSpCas9	negative selection	12158661
15506898	15506921	1	-	28162770	OCIAML2	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.16599479530148742	[63]	[397]	1	hSpCas9	negative selection	12158662
15504648	15504671	1	-	28162770	OCIAML2	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	-0.31630167885086724	[30]	[137]	-3	hSpCas9	negative selection	12158663
15495426	15495449	1	-	28162770	OCIAML2	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.4543280129130607	[21]	[88]	-4	hSpCas9	negative selection	12158664
15495352	15495375	1	+	28162770	OCIAML2	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-3.0555923259633175	[2]	[1]	-9	hSpCas9	negative selection	12158665
15507024	15507047	1	+	28162770	OCIAML2	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.22459846625358915	[127]	[828]	2	hSpCas9	negative selection	12158666
15506971	15506994	1	+	28162770	OCIAML3	viability	GTCGATGTTGGAGCCAGTGCGGG	CASP9	ENSG00000132906	-0.4521749459112039	[120]	[266]	-3	hSpCas9	negative selection	12328023
15506916	15506939	1	-	28162770	OCIAML3	viability	GCATTTCATGGTGGAGGTGAAGG	CASP9	ENSG00000132906	1.0920409855113073	[61]	[398]	8	hSpCas9	negative selection	12328024
15506036	15506059	1	-	28162770	OCIAML3	viability	GAGCTGGCGCAGCAGGACCACGG	CASP9	ENSG00000132906	-1.5130876449405957	[51]	[54]	-8	hSpCas9	negative selection	12328025
15518140	15518163	1	-	28162770	OCIAML3	viability	ACCGGAAACACCCAGACCAGTGG	CASP9	ENSG00000132906	0.05806905625553016	[6]	[21]	0	hSpCas9	negative selection	12328026
15518124	15518147	1	-	28162770	OCIAML3	viability	CCAGTGGACATTGGTTCTGGAGG	CASP9	ENSG00000132906	0.9836500597737596	[32]	[196]	8	hSpCas9	negative selection	12328027
15506898	15506921	1	-	28162770	OCIAML3	viability	GAAGGGCGACCTGACTGCCAAGG	CASP9	ENSG00000132906	0.8239831763440282	[60]	[325]	7	hSpCas9	negative selection	12328028
15504648	15504671	1	-	28162770	OCIAML3	viability	CCAGCTGCCCCAGCCTGGGAGGG	CASP9	ENSG00000132906	0.5455437120746305	[63]	[281]	5	hSpCas9	negative selection	12328029
15495426	15495449	1	-	28162770	OCIAML3	viability	GAAAGACCATGGGTTTGAGGTGG	CASP9	ENSG00000132906	-0.19545826383388842	[21]	[57]	-1	hSpCas9	negative selection	12328030
15495352	15495375	1	+	28162770	OCIAML3	viability	CAAACCTTCCTGGAACGGGGTGG	CASP9	ENSG00000132906	-0.33097323449036953	[4]	[11]	-3	hSpCas9	negative selection	12328031
15507024	15507047	1	+	28162770	OCIAML3	viability	CATTGTTGATAATGAGGCAGTGG	CASP9	ENSG00000132906	0.30281691170044134	[162]	[606]	3	hSpCas9	negative selection	12328032