Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:378807
• Symbol:CATSPER4
• Description:cation channel sperm associated 4

DataSource: http://genomecrispr.dkfz.de/#!/results/CATSPER4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
26191396	26191419	1	-	26472758	Jiyoye	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	1.7822148128527981	[31]	[82]	8	hSpCas9	negative selection	23914
26199946	26199969	1	-	26472758	Jiyoye	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-1.2366808082688516	[24]	[7]	-7	hSpCas9	negative selection	23915
26197969	26197992	1	+	26472758	Jiyoye	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	2.9921378822270293	[0]	[5]	9	hSpCas9	negative selection	23916
26190632	26190655	1	+	26472758	Jiyoye	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	0.6461825166932178	[110]	[130]	5	hSpCas9	negative selection	23917
26190705	26190728	1	+	26472758	Jiyoye	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	2.1149946300125633	[29]	[97]	9	hSpCas9	negative selection	23918
26190722	26190745	1	+	26472758	Jiyoye	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	0.6362008951747684	[92]	[108]	4	hSpCas9	negative selection	23919
26193830	26193853	1	-	26472758	Jiyoye	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	1.8031040578370123	[18]	[49]	8	hSpCas9	negative selection	23920
26197995	26198018	1	-	26472758	Jiyoye	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.49552741713921167	[42]	[22]	-4	hSpCas9	negative selection	23921
26198011	26198034	1	-	26472758	Jiyoye	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	-0.04850410227031621	[191]	[139]	0	hSpCas9	negative selection	23922
26199887	26199910	1	+	26472758	Jiyoye	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	0.6119951733943716	[58]	[67]	4	hSpCas9	negative selection	23923
26191396	26191419	1	-	26472758	KBM7	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	0.2207805728420904	[283,196]	[101,154]	2	hSpCas9	negative selection	215032
26199946	26199969	1	-	26472758	KBM7	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	0.8730828266041737	[247,140]	[189,139]	8	hSpCas9	negative selection	215033
26197969	26197992	1	+	26472758	KBM7	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	-0.5802170740199131	[84,24]	[17,14]	-5	hSpCas9	negative selection	215034
26190632	26190655	1	+	26472758	KBM7	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	0.2065804645457931	[470,249]	[191,188]	2	hSpCas9	negative selection	215035
26190705	26190728	1	+	26472758	KBM7	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.5261823066539943	[805,433]	[399,416]	6	hSpCas9	negative selection	215036
26190722	26190745	1	+	26472758	KBM7	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.862925189169647	[610,440]	[107,157]	-6	hSpCas9	negative selection	215037
26193830	26193853	1	-	26472758	KBM7	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	-0.4216949562320602	[209,259]	[134,37]	-4	hSpCas9	negative selection	215038
26197995	26198018	1	-	26472758	KBM7	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.6322042895882338	[174,102]	[26,53]	-5	hSpCas9	negative selection	215039
26198011	26198034	1	-	26472758	KBM7	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	0.8310147913112867	[720,786]	[389,856]	8	hSpCas9	negative selection	215040
26199887	26199910	1	+	26472758	KBM7	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	0.7879702350982725	[290,288]	[245,227]	8	hSpCas9	negative selection	215041
26191396	26191419	1	-	26472758	Raji	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	0.7068456057898709	[65]	[24]	6	hSpCas9	negative selection	406150
26199946	26199969	1	-	26472758	Raji	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-0.01126096112501962	[151]	[34]	0	hSpCas9	negative selection	406151
26197969	26197992	1	+	26472758	Raji	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	1.6923460360947558	[7]	[5]	9	hSpCas9	negative selection	406152
26190632	26190655	1	+	26472758	Raji	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	0.15985095526773496	[215]	[55]	1	hSpCas9	negative selection	406153
26190705	26190728	1	+	26472758	Raji	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.40952697824650985	[278]	[85]	4	hSpCas9	negative selection	406154
26190722	26190745	1	+	26472758	Raji	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	0.5315232417596959	[157]	[52]	5	hSpCas9	negative selection	406155
26193830	26193853	1	-	26472758	Raji	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	-1.8416325359075958	[138]	[8]	-8	hSpCas9	negative selection	406156
26197995	26198018	1	-	26472758	Raji	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.5014257073019246	[60]	[9]	-4	hSpCas9	negative selection	406157
26198011	26198034	1	-	26472758	Raji	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	0.1856087026791018	[340]	[89]	1	hSpCas9	negative selection	406158
26199887	26199910	1	+	26472758	Raji	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	-0.5791169918096191	[205]	[31]	-4	hSpCas9	negative selection	406159
26191396	26191419	1	-	26472758	K562	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	-1.7817335601895217	[166]	[40]	-7	hSpCas9	negative selection	597268
26199946	26199969	1	-	26472758	K562	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-1.3200796704949935	[209]	[70]	-6	hSpCas9	negative selection	597269
26197969	26197992	1	+	26472758	K562	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	-4.8430441135838915	[33]	[0]	-9	hSpCas9	negative selection	597270
26190632	26190655	1	+	26472758	K562	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	0.6766779674738777	[228]	[308]	5	hSpCas9	negative selection	597271
26190705	26190728	1	+	26472758	K562	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.4338166850823467	[555]	[633]	3	hSpCas9	negative selection	597272
26190722	26190745	1	+	26472758	K562	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-2.634143144883577	[352]	[47]	-8	hSpCas9	negative selection	597273
26193830	26193853	1	-	26472758	K562	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	0.7382333403294079	[195]	[275]	6	hSpCas9	negative selection	597274
26197995	26198018	1	-	26472758	K562	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-2.866005262027204	[94]	[10]	-8	hSpCas9	negative selection	597275
26198011	26198034	1	-	26472758	K562	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	-0.1659753976622957	[516]	[388]	-1	hSpCas9	negative selection	597276
26199887	26199910	1	+	26472758	K562	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	-0.22806904379629658	[332]	[239]	-1	hSpCas9	negative selection	597277
26190665	26190688	1	+	26627737	DLD1	viability	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	-0.18047775994945203	[309]	[143,71,45]	-2	hSpCas9	negative selection	770401
26191369	26191392	1	-	26627737	DLD1	viability	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.2325913576424976	[377]	[184,105,125]	2	hSpCas9	negative selection	770402
26197996	26198019	1	-	26627737	DLD1	viability	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	1.0974732270415486	[723]	[576,523,370]	8	hSpCas9	negative selection	770403
26200007	26200030	1	+	26627737	DLD1	viability	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	0.444803812280694	[287]	[167,106,95]	4	hSpCas9	negative selection	770404
26200859	26200882	1	-	26627737	DLD1	viability	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.5410601750475901	[488]	[197,332,151]	5	hSpCas9	negative selection	770405
26201413	26201436	1	+	26627737	DLD1	viability	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	2.465646811481461	[11]	[13,24,22]	9	hSpCas9	negative selection	770406
26190665	26190688	1	+	26627737	GBM cells	viability after 5 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	-0.11668298016533285	[278]	[128,146]	-2	hSpCas9	negative selection	852716
26191369	26191392	1	-	26627737	GBM cells	viability after 5 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.06369557305203821	[280]	[191,122]	1	hSpCas9	negative selection	852717
26197996	26198019	1	-	26627737	GBM cells	viability after 5 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.526945097498728	[406]	[358,269]	7	hSpCas9	negative selection	852718
26200007	26200030	1	+	26627737	GBM cells	viability after 5 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	0.04701251387481942	[147]	[37,125]	0	hSpCas9	negative selection	852719
26200859	26200882	1	-	26627737	GBM cells	viability after 5 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.2575106798204445	[403]	[261,255]	4	hSpCas9	negative selection	852720
26201413	26201436	1	+	26627737	GBM cells	viability after 5 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	1.6188059556929502	[16]	[23,31]	9	hSpCas9	negative selection	852721
26190665	26190688	1	+	26627737	GBM cells	viability after 13 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.13474561817050534	[278]	[147,180]	1	hSpCas9	negative selection	935031
26191369	26191392	1	-	26627737	GBM cells	viability after 13 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.04378326557146189	[280]	[133,175]	0	hSpCas9	negative selection	935032
26197996	26198019	1	-	26627737	GBM cells	viability after 13 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.4051482397544348	[406]	[319,269]	5	hSpCas9	negative selection	935033
26200007	26200030	1	+	26627737	GBM cells	viability after 13 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	0.25074490654557313	[147]	[78,108]	3	hSpCas9	negative selection	935034
26200859	26200882	1	-	26627737	GBM cells	viability after 13 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.16269286564599483	[403]	[294,204]	2	hSpCas9	negative selection	935035
26201413	26201436	1	+	26627737	GBM cells	viability after 13 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	0.598201631227266	[16]	[8,17]	7	hSpCas9	negative selection	935036
26190665	26190688	1	+	26627737	GBM cells	viability after 21 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.0917008420735666	[278]	[160,161]	1	hSpCas9	negative selection	1017346
26191369	26191392	1	-	26627737	GBM cells	viability after 21 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	-0.3573560896606722	[280]	[126,111]	-3	hSpCas9	negative selection	1017347
26197996	26198019	1	-	26627737	GBM cells	viability after 21 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	1.1434318028415884	[406]	[512,465]	9	hSpCas9	negative selection	1017348
26200007	26200030	1	+	26627737	GBM cells	viability after 21 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	0.6857302754526802	[147]	[144,114]	7	hSpCas9	negative selection	1017349
26200859	26200882	1	-	26627737	GBM cells	viability after 21 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.4928621882886165	[403]	[311,305]	5	hSpCas9	negative selection	1017350
26201413	26201436	1	+	26627737	GBM cells	viability after 21 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	0.3830664033895159	[16]	[10,12]	4	hSpCas9	negative selection	1017351
26190665	26190688	1	+	26627737	RPE1	viability after 9 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	3.9398488482391456	[72]	[341,361]	9	hSpCas9	negative selection	1099661
26191369	26191392	1	-	26627737	RPE1	viability after 9 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.3107822103775148	[773]	[238,379]	2	hSpCas9	negative selection	1099662
26197996	26198019	1	-	26627737	RPE1	viability after 9 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.8690828942994905	[1167]	[611,739]	5	hSpCas9	negative selection	1099663
26200007	26200030	1	+	26627737	RPE1	viability after 9 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	1.5495391471970297	[210]	[157,238]	8	hSpCas9	negative selection	1099664
26200859	26200882	1	-	26627737	RPE1	viability after 9 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.7984145312188236	[778]	[376,484]	5	hSpCas9	negative selection	1099665
26201413	26201436	1	+	26627737	RPE1	viability after 9 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	3.424408756087504	[13]	[43,50]	9	hSpCas9	negative selection	1099666
26190665	26190688	1	+	26627737	RPE1	viability after 12 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	3.85181875029899	[72]	[339,222]	9	hSpCas9	negative selection	1181976
26191369	26191392	1	-	26627737	RPE1	viability after 12 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.5544779074382166	[773]	[352,254]	3	hSpCas9	negative selection	1181977
26197996	26198019	1	-	26627737	RPE1	viability after 12 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	1.0679800281186842	[1167]	[636,679]	6	hSpCas9	negative selection	1181978
26200007	26200030	1	+	26627737	RPE1	viability after 12 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	1.479836134630941	[210]	[76,243]	7	hSpCas9	negative selection	1181979
26200859	26200882	1	-	26627737	RPE1	viability after 12 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	1.0882934194652287	[778]	[461,426]	6	hSpCas9	negative selection	1181980
26201413	26201436	1	+	26627737	RPE1	viability after 12 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	3.6132142513771357	[13]	[12,80]	9	hSpCas9	negative selection	1181981
26190665	26190688	1	+	26627737	RPE1	viability after 15 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	4.5710979631988025	[72]	[582,401]	9	hSpCas9	negative selection	1264291
26191369	26191392	1	-	26627737	RPE1	viability after 15 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.5549039518658776	[773]	[256,383]	3	hSpCas9	negative selection	1264292
26197996	26198019	1	-	26627737	RPE1	viability after 15 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	1.360075695595739	[1167]	[952,746]	7	hSpCas9	negative selection	1264293
26200007	26200030	1	+	26627737	RPE1	viability after 15 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	1.328880733129418	[210]	[68,227]	7	hSpCas9	negative selection	1264294
26200859	26200882	1	-	26627737	RPE1	viability after 15 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	1.469480471318441	[778]	[540,676]	7	hSpCas9	negative selection	1264295
26201413	26201436	1	+	26627737	RPE1	viability after 15 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	3.1017607894019164	[13]	[5,60]	9	hSpCas9	negative selection	1264296
26190665	26190688	1	+	26627737	RPE1	viability after 18 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	4.740918894506642	[72]	[403,657]	9	hSpCas9	negative selection	1346606
26191369	26191392	1	-	26627737	RPE1	viability after 18 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	-0.0852681746630581	[773]	[251,137]	0	hSpCas9	negative selection	1346607
26197996	26198019	1	-	26627737	RPE1	viability after 18 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	1.4354438368272655	[1167]	[794,913]	7	hSpCas9	negative selection	1346608
26200007	26200030	1	+	26627737	RPE1	viability after 18 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	1.783802092363976	[210]	[66,333]	8	hSpCas9	negative selection	1346609
26200859	26200882	1	-	26627737	RPE1	viability after 18 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.9370591958741251	[778]	[358,448]	5	hSpCas9	negative selection	1346610
26201413	26201436	1	+	26627737	RPE1	viability after 18 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	4.364117045736193	[13]	[42,114]	9	hSpCas9	negative selection	1346611
26190665	26190688	1	+	26627737	HeLa	viability after 8 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.7780110981751828	[227]	[290,179,72]	6	hSpCas9	negative selection	1428921
26191369	26191392	1	-	26627737	HeLa	viability after 8 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.3194246938697778	[482]	[171,422,177]	3	hSpCas9	negative selection	1428922
26197996	26198019	1	-	26627737	HeLa	viability after 8 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	1.0402525940761378	[395]	[516,124,449]	7	hSpCas9	negative selection	1428923
26200007	26200030	1	+	26627737	HeLa	viability after 8 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.04281369594741885	[278]	[49,205,84]	0	hSpCas9	negative selection	1428924
26200859	26200882	1	-	26627737	HeLa	viability after 8 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.45872800534691294	[926]	[335,380,180]	-4	hSpCas9	negative selection	1428925
26201413	26201436	1	+	26627737	HeLa	viability after 8 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	2.491158357211982	[11]	[70,22,4]	9	hSpCas9	negative selection	1428926
26190665	26190688	1	+	26627737	HeLa	viability after 12 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.6983786215090542	[227]	[196,95,172]	5	hSpCas9	negative selection	1511236
26191369	26191392	1	-	26627737	HeLa	viability after 12 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.08926208162008431	[482]	[197,255,177]	0	hSpCas9	negative selection	1511237
26197996	26198019	1	-	26627737	HeLa	viability after 12 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	1.3802842711084606	[395]	[543,458,274]	8	hSpCas9	negative selection	1511238
26200007	26200030	1	+	26627737	HeLa	viability after 12 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.2847591824255917	[278]	[149,80,55]	-3	hSpCas9	negative selection	1511239
26200859	26200882	1	-	26627737	HeLa	viability after 12 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.3748572705335351	[926]	[252,248,387]	-3	hSpCas9	negative selection	1511240
26201413	26201436	1	+	26627737	HeLa	viability after 12 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	4.040588703406981	[11]	[129,64,52]	9	hSpCas9	negative selection	1511241
26190665	26190688	1	+	26627737	HeLa	viability after 15 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.42418295348437984	[227]	[158,91,121]	3	hSpCas9	negative selection	1593551
26191369	26191392	1	-	26627737	HeLa	viability after 15 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.46661558601275266	[482]	[301,213,300]	4	hSpCas9	negative selection	1593552
26197996	26198019	1	-	26627737	HeLa	viability after 15 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	1.4311084299331054	[395]	[463,353,489]	8	hSpCas9	negative selection	1593553
26200007	26200030	1	+	26627737	HeLa	viability after 15 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.53744872784281	[278]	[98,14,123]	-5	hSpCas9	negative selection	1593554
26200859	26200882	1	-	26627737	HeLa	viability after 15 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.5380367281050622	[926]	[52,280,463]	-5	hSpCas9	negative selection	1593555
26201413	26201436	1	+	26627737	HeLa	viability after 15 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	2.638921808249753	[11]	[44,40,2]	9	hSpCas9	negative selection	1593556
26190665	26190688	1	+	26627737	HeLa	viability after 18 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.38661837664463994	[227]	[98,77,121]	3	hSpCas9	negative selection	1675866
26191369	26191392	1	-	26627737	HeLa	viability after 18 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.49796294468792157	[482]	[215,174,300]	4	hSpCas9	negative selection	1675867
26197996	26198019	1	-	26627737	HeLa	viability after 18 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	1.4324286374030883	[395]	[304,301,489]	8	hSpCas9	negative selection	1675868
26200007	26200030	1	+	26627737	HeLa	viability after 18 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.5638674502298036	[278]	[63,11,123]	-5	hSpCas9	negative selection	1675869
26200859	26200882	1	-	26627737	HeLa	viability after 18 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.5712369163618775	[926]	[26,228,463]	-5	hSpCas9	negative selection	1675870
26201413	26201436	1	+	26627737	HeLa	viability after 18 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	2.523448420600837	[11]	[23,35,2]	9	hSpCas9	negative selection	1675871
26190665	26190688	1	+	26627737	HCT116	viability after 6 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	1.5790115484303433	[116]	[72,44]	7	hSpCas9	negative selection	1758181
26191369	26191392	1	-	26627737	HCT116	viability after 6 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	2.650325387025437	[413]	[396,414]	9	hSpCas9	negative selection	1758182
26197996	26198019	1	-	26627737	HCT116	viability after 6 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.06913274379133894	[1516]	[449,139]	0	hSpCas9	negative selection	1758183
26200007	26200030	1	+	26627737	HCT116	viability after 6 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.071505343895514	[426]	[108,38]	0	hSpCas9	negative selection	1758184
26200859	26200882	1	-	26627737	HCT116	viability after 6 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.2623594355110662	[1178]	[75,302]	1	hSpCas9	negative selection	1758185
26201413	26201436	1	+	26627737	HCT116	viability after 6 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	0.12461411292019164	[48]	[19,1]	0	hSpCas9	negative selection	1758186
26190665	26190688	1	+	26627737	HCT116	viability after 8 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	-0.7229672152204397	[433]	[183,76,173]	-7	hSpCas9	negative selection	1840496
26191369	26191392	1	-	26627737	HCT116	viability after 8 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.6729951896502977	[254]	[303,102,265]	6	hSpCas9	negative selection	1840497
26197996	26198019	1	-	26627737	HCT116	viability after 8 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.030804811438821078	[574]	[288,240,438]	0	hSpCas9	negative selection	1840498
26200007	26200030	1	+	26627737	HCT116	viability after 8 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.4476305186654468	[246]	[156,91,51]	-5	hSpCas9	negative selection	1840499
26200859	26200882	1	-	26627737	HCT116	viability after 8 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.26281424577215906	[626]	[221,295,343]	-3	hSpCas9	negative selection	1840500
26201413	26201436	1	+	26627737	HCT116	viability after 8 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	1.3622894262324676	[14]	[30,17,14]	9	hSpCas9	negative selection	1840501
26190665	26190688	1	+	26627737	HCT116	viability after 9 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	2.1115369615539654	[116]	[277,21]	9	hSpCas9	negative selection	1922811
26191369	26191392	1	-	26627737	HCT116	viability after 9 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	1.407235281280295	[413]	[276,305]	8	hSpCas9	negative selection	1922812
26197996	26198019	1	-	26627737	HCT116	viability after 9 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.6839789893608215	[1516]	[590,697]	5	hSpCas9	negative selection	1922813
26200007	26200030	1	+	26627737	HCT116	viability after 9 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.12979119735840572	[426]	[106,101]	-1	hSpCas9	negative selection	1922814
26200859	26200882	1	-	26627737	HCT116	viability after 9 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.3098782005186158	[1178]	[301,215]	-2	hSpCas9	negative selection	1922815
26201413	26201436	1	+	26627737	HCT116	viability after 9 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	-3.7097200327617403	[48]	[0,0]	-9	hSpCas9	negative selection	1922816
26190665	26190688	1	+	26627737	HCT116	viability after 12 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	-0.37523605002749294	[433]	[100,253,180]	-4	hSpCas9	negative selection	2005126
26191369	26191392	1	-	26627737	HCT116	viability after 12 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.21065126130519068	[254]	[176,59,223]	2	hSpCas9	negative selection	2005127
26197996	26198019	1	-	26627737	HCT116	viability after 12 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.5719039437400559	[574]	[432,532,384]	5	hSpCas9	negative selection	2005128
26200007	26200030	1	+	26627737	HCT116	viability after 12 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.47590469206147035	[246]	[130,64,79]	-5	hSpCas9	negative selection	2005129
26200859	26200882	1	-	26627737	HCT116	viability after 12 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.3847612091720829	[626]	[263,289,202]	-4	hSpCas9	negative selection	2005130
26201413	26201436	1	+	26627737	HCT116	viability after 12 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	0.5407937302024197	[14]	[13,3,15]	5	hSpCas9	negative selection	2005131
26190665	26190688	1	+	26627737	HCT116	viability after 15 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	-0.5736393019407969	[433]	[206,196,103]	-5	hSpCas9	negative selection	2087441
26191369	26191392	1	-	26627737	HCT116	viability after 15 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.6515653605685854	[254]	[325,77,296]	6	hSpCas9	negative selection	2087442
26197996	26198019	1	-	26627737	HCT116	viability after 15 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.6068701655338029	[574]	[467,576,459]	5	hSpCas9	negative selection	2087443
26200007	26200030	1	+	26627737	HCT116	viability after 15 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.3779327216038587	[246]	[102,136,86]	-4	hSpCas9	negative selection	2087444
26200859	26200882	1	-	26627737	HCT116	viability after 15 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.13761082971317418	[626]	[280,550,342]	1	hSpCas9	negative selection	2087445
26201413	26201436	1	+	26627737	HCT116	viability after 15 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	1.6852940929683249	[14]	[25,36,19]	9	hSpCas9	negative selection	2087446
26190665	26190688	1	+	26627737	HCT116	viability after 18 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	-1.376842630428154	[433]	[61,125,49]	-8	hSpCas9	negative selection	2169756
26191369	26191392	1	-	26627737	HCT116	viability after 18 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.606825093849388	[254]	[124,146,298]	5	hSpCas9	negative selection	2169757
26197996	26198019	1	-	26627737	HCT116	viability after 18 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.9618061021347639	[574]	[512,555,554]	7	hSpCas9	negative selection	2169758
26200007	26200030	1	+	26627737	HCT116	viability after 18 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	0.008575369531255872	[246]	[179,132,42]	0	hSpCas9	negative selection	2169759
26200859	26200882	1	-	26627737	HCT116	viability after 18 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.04507950926940918	[626]	[172,440,255]	0	hSpCas9	negative selection	2169760
26201413	26201436	1	+	26627737	HCT116	viability after 18 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	0.3341647631592166	[14]	[16,0,9]	3	hSpCas9	negative selection	2169761
26195038	26195061	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCACTGCACTCCAGCCTGG	CATSPER4	ENSG00000188782	0.6031003623548207	[86,54]	[14,31]	2	dCas9-VP64	positive selection	2416291
26195541	26195564	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGCCACTGCACTCCAGCCCAGG	CATSPER4	ENSG00000188782	0.5268875283082193	[1,6]	[1,0]	2	dCas9-VP64	positive selection	2458611
26195038	26195061	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCACTGCACTCCAGCCTGG	CATSPER4	ENSG00000188782	-0.5652196159145948	[243,309]	[59,60]	-5	dCas9-VP64	positive selection	2511546
26195541	26195564	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGCCACTGCACTCCAGCCCAGG	CATSPER4	ENSG00000188782	1.3449939631950025	[38,32]	[23,34]	7	dCas9-VP64	positive selection	2553866
26190820	26190843	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAGGAAATCACGAACAAAGCGG	CATSPER4	ENSG00000188782	0.232571521086952	[4,4]	[4,4]	5	hSpCas9	positive selection	2976483
26190816	26190839	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTGTTCGTGATTTCCTGGCGG	CATSPER4	ENSG00000188782	0.23224181339136	[3,4]	[4,4]	5	hSpCas9	positive selection	2976484
26190802	26190825	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	-0.043142666998686796	[3,2]	[2,1]	0	hSpCas9	positive selection	2976485
26190633	26190656	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.8017622717037372	[3,2]	[2,0]	-8	hSpCas9	positive selection	2976486
26190820	26190843	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAGGAAATCACGAACAAAGCGG	CATSPER4	ENSG00000188782	0.13987434810820748	[4,4]	[4,2]	2	hSpCas9	positive selection	3044341
26190816	26190839	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTGTTCGTGATTTCCTGGCGG	CATSPER4	ENSG00000188782	0.8462589910129882	[3,3]	[4,5]	9	hSpCas9	positive selection	3044342
26190802	26190825	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	0.024472014550794202	[3,3]	[4,0]	0	hSpCas9	positive selection	3044343
26190633	26190656	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.05720493916041608	[3,3]	[1,1]	-1	hSpCas9	positive selection	3044344
26190770	26190793		-	24336571	A375	resistance to PLX after 7 days	CCGACCGTAGGACTCGTGAATGG	CATSPER4	ENSG00000188782	-0.09745480508040838	[7,5]	[5,6]	-3	hSpCas9	positive selection	3160807
26190819	26190842		-	24336571	A375	resistance to PLX after 7 days	CCGCTTTGTTCGTGATTTCCTGG	CATSPER4	ENSG00000188782	-0.2217553487576416	[13,15]	[12,11]	-6	hSpCas9	positive selection	3160808
26190801	26190824		+	24336571	A375	resistance to PLX after 7 days	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	0.1843723132843187	[12,12]	[15,13]	5	hSpCas9	positive selection	3160809
26191390	26191413		-	24336571	A375	resistance to PLX after 7 days	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	-0.6266480626504609	[4,5]	[2,3]	-9	hSpCas9	positive selection	3160810
26190770	26190793		-	24336571	A375	resistance to PLX after 14 days	CCGACCGTAGGACTCGTGAATGG	CATSPER4	ENSG00000188782	1.4442848332614533	[4,4]	[5,5]	8	hSpCas9	positive selection	3218600
26190819	26190842		-	24336571	A375	resistance to PLX after 14 days	CCGCTTTGTTCGTGATTTCCTGG	CATSPER4	ENSG00000188782	-0.5258168186047572	[11,23]	[4,5]	-6	hSpCas9	positive selection	3218601
26190801	26190824		+	24336571	A375	resistance to PLX after 14 days	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	-0.3177784618914351	[15,18]	[5,5]	-4	hSpCas9	positive selection	3218602
26191390	26191413		-	24336571	A375	resistance to PLX after 14 days	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	-0.8353840816507266	[5,9]	[1,1]	-8	hSpCas9	positive selection	3218603
26190770	26190793		-	24336571	A375	viability after 7 days	CCGACCGTAGGACTCGTGAATGG	CATSPER4	ENSG00000188782	0.1147086739987776	[6]	[7,5]	1	hSpCas9	negative selection	3276393
26190819	26190842		-	24336571	A375	viability after 7 days	CCGCTTTGTTCGTGATTTCCTGG	CATSPER4	ENSG00000188782	0.12050919481020732	[14]	[13,15]	1	hSpCas9	negative selection	3276394
26190801	26190824		+	24336571	A375	viability after 7 days	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	0.1778915614443551	[11]	[12,12]	2	hSpCas9	negative selection	3276395
26191390	26191413		-	24336571	A375	viability after 7 days	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.30432374010298613	[4]	[4,5]	4	hSpCas9	negative selection	3276396
26190770	26190793		-	24336571	A375	viability after 14 days	CCGACCGTAGGACTCGTGAATGG	CATSPER4	ENSG00000188782	-0.3209957448334191	[6]	[4,4]	-4	hSpCas9	negative selection	3334186
26190819	26190842		-	24336571	A375	viability after 14 days	CCGCTTTGTTCGTGATTTCCTGG	CATSPER4	ENSG00000188782	0.38835346543312194	[14]	[11,23]	5	hSpCas9	negative selection	3334187
26190801	26190824		+	24336571	A375	viability after 14 days	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	0.5533256630878127	[11]	[15,18]	7	hSpCas9	negative selection	3334188
26191390	26191413		-	24336571	A375	viability after 14 days	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.7845437856477492	[4]	[5,9]	8	hSpCas9	negative selection	3334189
26190766	26190789	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.11401626029165614	[176,153]	[0,0]	0	hSpCas9	positive selection	3341175
26190655	26190678	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	-0.34676062098728566	[203,184]	[0,0]	-2	hSpCas9	positive selection	3341176
26191403	26191426	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	-1.5579838242884982	[446,453]	[0,0]	-9	hSpCas9	positive selection	3341177
26191390	26191413	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	1.0675016525658179	[72,72]	[0,0]	5	hSpCas9	positive selection	3360419
26193825	26193848	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	-2.1668400773722647	[686,686]	[0,0]	-9	hSpCas9	positive selection	3360420
26193809	26193832	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.028076007416413237	[155,155]	[0,0]	0	hSpCas9	positive selection	3360421
26190819	26190842	1	+	26780180	HT29	viability (Avana library 4 designs)	CCAGGAAATCACGAACAAAGCGG	CATSPER4	ENSG00000188782	0.281058514877849	[]	[]	1	hSpCas9	negative selection	3412764
26190816	26190839	1	-	26780180	HT29	viability (Avana library 4 designs)	CTTTGTTCGTGATTTCCTGGCGG	CATSPER4	ENSG00000188782	1.15954878437748	[]	[]	4	hSpCas9	negative selection	3412765
26190801	26190824	1	+	26780180	HT29	viability (Avana library 4 designs)	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	-1.11216988724156	[]	[]	-9	hSpCas9	negative selection	3412766
26190632	26190655	1	+	26780180	HT29	viability (Avana library 4 designs)	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	2.27520675732609	[]	[]	7	hSpCas9	negative selection	3412767
26190816	26190839	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTGTTCGTGATTTCCTGGCGG	CATSPER4	ENSG00000188782	2.50028974067684	[]	[]	4	hSpCas9	negative selection	3488394
26190819	26190842	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGGAAATCACGAACAAAGCGG	CATSPER4	ENSG00000188782	-3.6777149504387	[]	[]	-4	hSpCas9	negative selection	3488395
26190801	26190824	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	4.9313429959957	[]	[]	8	hSpCas9	negative selection	3488396
26190632	26190655	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-1.35186754279912	[]	[]	-2	hSpCas9	negative selection	3488397
26197966	26197989	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGTGCATGTGTGCATGGCGG	CATSPER4	ENSG00000188782	3.32649435262694	[]	[]	5	hSpCas9	negative selection	3488398
26193830	26193853	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	-2.67404809329257	[]	[]	-3	hSpCas9	negative selection	3488399
26190816	26190839	1	-	26780180	A375	viability (Avana lentiGuide)	CTTTGTTCGTGATTTCCTGGCGG	CATSPER4	ENSG00000188782	-1.93352150191412	[]	[]	-3	hSpCas9	negative selection	3597053
26190819	26190842	1	+	26780180	A375	viability (Avana lentiGuide)	CCAGGAAATCACGAACAAAGCGG	CATSPER4	ENSG00000188782	-6.32928363363974	[]	[]	-9	hSpCas9	negative selection	3597054
26190801	26190824	1	+	26780180	A375	viability (Avana lentiGuide)	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	-2.61145424875179	[]	[]	-4	hSpCas9	negative selection	3597055
26190632	26190655	1	+	26780180	A375	viability (Avana lentiGuide)	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	8.16061600507243	[]	[]	6	hSpCas9	negative selection	3597056
26197966	26197989	1	+	26780180	A375	viability (Avana lentiGuide)	TCTGGTGCATGTGTGCATGGCGG	CATSPER4	ENSG00000188782	1.60383595748212	[]	[]	1	hSpCas9	negative selection	3597057
26193830	26193853	1	-	26780180	A375	viability (Avana lentiGuide)	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	-7.261333192357	[]	[]	-9	hSpCas9	negative selection	3597058
26190816	26190839	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTGTTCGTGATTTCCTGGCGG	CATSPER4	ENSG00000188782	-0.09780947224596712	[5]	[5,4]	-2	hSpCas9	positive selection	3705712
26190819	26190842	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGGAAATCACGAACAAAGCGG	CATSPER4	ENSG00000188782	-0.1752544262399064	[5]	[5,3]	-3	hSpCas9	positive selection	3705713
26190801	26190824	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	-0.30380930375650117	[3]	[2,1]	-4	hSpCas9	positive selection	3705714
26190632	26190655	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	0.039456437559253627	[4]	[5,3]	1	hSpCas9	positive selection	3705715
26197966	26197989	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGTGCATGTGTGCATGGCGG	CATSPER4	ENSG00000188782	0.2547698644298487	[6]	[7,6]	7	hSpCas9	positive selection	3705716
26193830	26193853	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	-0.22804734449888686	[5]	[4,4]	-4	hSpCas9	positive selection	3705717
26190816	26190839	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTGTTCGTGATTTCCTGGCGG	CATSPER4	ENSG00000188782	0.2614081243283456	[6]	[6,6]	7	hSpCas9	positive selection	3814319
26190819	26190842	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGGAAATCACGAACAAAGCGG	CATSPER4	ENSG00000188782	-0.2548952600798245	[6]	[3,4]	-3	hSpCas9	positive selection	3814320
26190801	26190824	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	-0.04528661218797403	[4]	[2,4]	0	hSpCas9	positive selection	3814321
26190632	26190655	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	0.1587462551685526	[4]	[4,4]	4	hSpCas9	positive selection	3814322
26197966	26197989	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGTGCATGTGTGCATGGCGG	CATSPER4	ENSG00000188782	0.11697820820137733	[7]	[6,6]	2	hSpCas9	positive selection	3814323
26193830	26193853	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	0.2345040103395317	[5]	[5,5]	6	hSpCas9	positive selection	3814324
26190766	26190789	1	+	26780180	A375	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.702850653173652	[]	[]	2	hSpCas9	negative selection	3922624
26190655	26190678	1	+	26780180	A375	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	1.14922931147975	[]	[]	6	hSpCas9	negative selection	3922625
26193825	26193848	1	+	26780180	A375	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	-0.576870983098171	[]	[]	-9	hSpCas9	negative selection	3922626
26191390	26191413	1	-	26780180	A375	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.351849798097303	[]	[]	0	hSpCas9	negative selection	3922627
26193809	26193832	1	-	26780180	A375	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	1.0608694845828	[]	[]	5	hSpCas9	negative selection	3922628
26191403	26191426	1	+	26780180	A375	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	1.02767407441256	[]	[]	5	hSpCas9	negative selection	3922629
26190766	26190789	1	+	26780180	HT29	viability (GeCKOv2 library)	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.992315470526672	[]	[]	4	hSpCas9	negative selection	4030590
26190655	26190678	1	+	26780180	HT29	viability (GeCKOv2 library)	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	1.23188098299809	[]	[]	6	hSpCas9	negative selection	4030591
26193825	26193848	1	+	26780180	HT29	viability (GeCKOv2 library)	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	-0.611314213463748	[]	[]	-9	hSpCas9	negative selection	4030592
26191390	26191413	1	-	26780180	HT29	viability (GeCKOv2 library)	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	1.16842383981685	[]	[]	5	hSpCas9	negative selection	4030593
26193809	26193832	1	-	26780180	HT29	viability (GeCKOv2 library)	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	1.54786606005675	[]	[]	7	hSpCas9	negative selection	4030594
26191403	26191426	1	+	26780180	HT29	viability (GeCKOv2 library)	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.798638297254844	[]	[]	3	hSpCas9	negative selection	4030595
26190770	26190793	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGACCGTAGGACTCGTGAATGG	CATSPER4	ENSG00000188782	0.3300134930478918	[2]	[1,2]	7	hSpCas9	positive selection	4188900
26190819	26190842	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGCTTTGTTCGTGATTTCCTGG	CATSPER4	ENSG00000188782	-0.013993708198159252	[3]	[2,2]	0	hSpCas9	positive selection	4188901
26190801	26190824	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	-0.1288028367464002	[3]	[1,2]	-3	hSpCas9	positive selection	4188902
26191390	26191413	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	-0.6040491833813064	[2]	[0,0]	-9	hSpCas9	positive selection	4188903
26190770	26190793	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGACCGTAGGACTCGTGAATGG	CATSPER4	ENSG00000188782	1.237920653522174	[2]	[0,0,2,3]	8	hSpCas9	positive selection	4252922
26190819	26190842	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGCTTTGTTCGTGATTTCCTGG	CATSPER4	ENSG00000188782	0.33062445999758006	[3]	[2,0,3,0]	2	hSpCas9	positive selection	4252923
26190801	26190824	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCAAGTGCTCATCAACCGCCAGG	CATSPER4	ENSG00000188782	0.008007907484504362	[2]	[0,2,1,0]	0	hSpCas9	positive selection	4252924
26191390	26191413	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.11621306748456986	[3]	[1,1,0,0]	0	hSpCas9	positive selection	4252925
26190766	26190789	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.24425278075977638	[3]	[2,3]	5	hSpCas9	positive selection	4261063
26190655	26190678	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.36808846898721065	[3]	[3,3]	7	hSpCas9	positive selection	4261064
26191403	26191426	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.20321215127315928	[4]	[4,3]	4	hSpCas9	positive selection	4261065
26191390	26191413	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.12176537856135616	[1]	[1,1]	2	hSpCas9	positive selection	4325341
26193825	26193848	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.5412173518888501	[4]	[4,4]	9	hSpCas9	positive selection	4325342
26193809	26193832	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.35665050462991066	[2]	[2,0]	-6	hSpCas9	positive selection	4325343
26190706	26190728	1	+	27760321	OCIAML3	viability	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.1357505267922441	[387,331]	[267,360]	1	hSpCas9	negative selection	4385889
26190782	26190804	1	-	27760321	OCIAML3	viability	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.5416419169313369	[1311,1172]	[1215,1668]	6	hSpCas9	negative selection	4385890
26190825	26190847	1	+	27760321	OCIAML3	viability	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	0.05812126217927949	[174,149]	[48,239]	0	hSpCas9	negative selection	4385891
26197995	26198017	1	-	27760321	OCIAML3	viability	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.16056619327115684	[956,742]	[663,833]	1	hSpCas9	negative selection	4385892
26198293	26198315	1	-	27760321	OCIAML3	viability	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	1.1467361144077337	[47,36]	[79,63]	9	hSpCas9	negative selection	4385893
26190706	26190728	1	+	27760321	OCIAML2	viability	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.08248610610970894	[387,331]	[268,357]	1	hSpCas9	negative selection	4469352
26190782	26190804	1	-	27760321	OCIAML2	viability	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.24689601377338444	[1311,1172]	[1059,1363]	3	hSpCas9	negative selection	4469353
26190825	26190847	1	+	27760321	OCIAML2	viability	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	-0.09417876569214512	[174,149]	[92,161]	-1	hSpCas9	negative selection	4469354
26197995	26198017	1	-	27760321	OCIAML2	viability	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.2941441184295137	[956,742]	[517,607]	-4	hSpCas9	negative selection	4469355
26198293	26198315	1	-	27760321	OCIAML2	viability	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	-0.25928434351701446	[47,36]	[15,44]	-3	hSpCas9	negative selection	4469356
26190706	26190728	1	+	27760321	MV411	viability	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	1.2238564775810081	[387,331]	[503,626]	8	hSpCas9	negative selection	4552815
26190782	26190804	1	-	27760321	MV411	viability	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.7120309828294267	[1311,1172]	[1549,1027]	5	hSpCas9	negative selection	4552816
26190825	26190847	1	+	27760321	MV411	viability	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	0.7963966315747529	[174,149]	[275,49]	6	hSpCas9	negative selection	4552817
26197995	26198017	1	-	27760321	MV411	viability	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.15693790892247006	[956,742]	[580,680]	1	hSpCas9	negative selection	4552818
26198293	26198315	1	-	27760321	MV411	viability	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	0.2271421058874612	[47,36]	[16,55]	1	hSpCas9	negative selection	4552819
26190706	26190728	1	+	27760321	HL60	viability	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.5900308750291077	[387,331]	[252,132]	-6	hSpCas9	negative selection	4636278
26190782	26190804	1	-	27760321	HL60	viability	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.5970874499467964	[1311,1172]	[1741,1311]	7	hSpCas9	negative selection	4636279
26190825	26190847	1	+	27760321	HL60	viability	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	-1.8159941656163843	[174,149]	[56,16]	-9	hSpCas9	negative selection	4636280
26197995	26198017	1	-	27760321	HL60	viability	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.2806206701936773	[956,742]	[503,634]	-3	hSpCas9	negative selection	4636281
26198293	26198315	1	-	27760321	HL60	viability	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	-0.6149683241477981	[47,36]	[5,39]	-6	hSpCas9	negative selection	4636282
26190706	26190728	1	+	27760321	HT1080	viability	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.1773711433606785	[331,258]	[124,141]	0	hSpCas9	negative selection	4719741
26190782	26190804	1	-	27760321	HT1080	viability	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	1.181424204785657	[1172,915]	[558,1364]	6	hSpCas9	negative selection	4719742
26190825	26190847	1	+	27760321	HT1080	viability	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	-1.0010219383617702	[149,116]	[6,47]	-4	hSpCas9	negative selection	4719743
26197995	26198017	1	-	27760321	HT1080	viability	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.5644558471062693	[742,579]	[213,138]	-3	hSpCas9	negative selection	4719744
26198293	26198315	1	-	27760321	HT1080	viability	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	0.24967235123074127	[36,28]	[28,0]	1	hSpCas9	negative selection	4719745
26190706	26190728	1	+	27760321	HT29	viability after 7 days	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.03194143987543496	[331,258]	[615,314,269]	0	hSpCas9	negative selection	4803204
26190782	26190804	1	-	27760321	HT29	viability after 7 days	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.44634714006724274	[1172,915]	[1828,1860,1797]	6	hSpCas9	negative selection	4803205
26190825	26190847	1	+	27760321	HT29	viability after 7 days	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	-1.0246147937904642	[149,116]	[137,81,41]	-8	hSpCas9	negative selection	4803206
26197995	26198017	1	-	27760321	HT29	viability after 7 days	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.20568949589808538	[742,579]	[1053,899,996]	3	hSpCas9	negative selection	4803207
26198293	26198315	1	-	27760321	HT29	viability after 7 days	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	-0.1945659631902399	[36,28]	[5,70,29]	-3	hSpCas9	negative selection	4803208
26190706	26190728	1	+	27760321	HT29	viability after 25 days	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.23309637335932948	[331,258]	[313,256,288]	-2	hSpCas9	negative selection	4886667
26190782	26190804	1	-	27760321	HT29	viability after 25 days	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.6444544471111244	[1172,915]	[1506,1767,2397]	7	hSpCas9	negative selection	4886668
26190825	26190847	1	+	27760321	HT29	viability after 25 days	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	-0.061250998160021775	[149,116]	[109,138,196]	0	hSpCas9	negative selection	4886669
26197995	26198017	1	-	27760321	HT29	viability after 25 days	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.4011915087092689	[742,579]	[992,992,1008]	4	hSpCas9	negative selection	4886670
26198293	26198315	1	-	27760321	HT29	viability after 25 days	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	1.0250947764618306	[36,28]	[25,133,72]	9	hSpCas9	negative selection	4886671
26190706	26190728	1	+	27760321	HT29	viability after 22 days	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.31264730821249026	[331,258]	[260,237,326]	-3	hSpCas9	negative selection	4970130
26190782	26190804	1	-	27760321	HT29	viability after 22 days	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.7180461873683439	[1172,915]	[2018,1644,2296]	7	hSpCas9	negative selection	4970131
26190825	26190847	1	+	27760321	HT29	viability after 22 days	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	0.40330240748757284	[149,116]	[195,161,254]	4	hSpCas9	negative selection	4970132
26197995	26198017	1	-	27760321	HT29	viability after 22 days	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.3918347667043688	[742,579]	[1151,963,888]	4	hSpCas9	negative selection	4970133
26198293	26198315	1	-	27760321	HT29	viability after 22 days	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	-0.13600059853057944	[36,28]	[8,47,47]	-1	hSpCas9	negative selection	4970134
26190706	26190728	1	+	27760321	HT29	viability after 19 days	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.01989163014491413	[331,258]	[568,343,145]	0	hSpCas9	negative selection	5053593
26190782	26190804	1	-	27760321	HT29	viability after 19 days	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.6685740169874197	[1172,915]	[1830,1847,2004]	6	hSpCas9	negative selection	5053594
26190825	26190847	1	+	27760321	HT29	viability after 19 days	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	-0.8947487887315111	[149,116]	[144,55,52]	-6	hSpCas9	negative selection	5053595
26197995	26198017	1	-	27760321	HT29	viability after 19 days	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.2672374755254264	[742,579]	[1177,913,675]	2	hSpCas9	negative selection	5053596
26198293	26198315	1	-	27760321	HT29	viability after 19 days	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	-0.6833257214189383	[36,28]	[23,7,37]	-5	hSpCas9	negative selection	5053597
26190706	26190728	1	+	27760321	HT29	viability after 16 days	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.5952590378608549	[331,258]	[487,314,698]	7	hSpCas9	negative selection	5137056
26190782	26190804	1	-	27760321	HT29	viability after 16 days	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.550407212226786	[1172,915]	[1329,1943,1817]	6	hSpCas9	negative selection	5137057
26190825	26190847	1	+	27760321	HT29	viability after 16 days	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	0.0449075446523608	[149,116]	[59,127,265]	0	hSpCas9	negative selection	5137058
26197995	26198017	1	-	27760321	HT29	viability after 16 days	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.3947788503622144	[742,579]	[1308,1037,601]	4	hSpCas9	negative selection	5137059
26198293	26198315	1	-	27760321	HT29	viability after 16 days	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	0.4990112715315971	[36,28]	[107,45,7]	6	hSpCas9	negative selection	5137060
26190706	26190728	1	+	27760321	HT29	viability after 13 days	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.2089946965936299	[331,258]	[404,197,286]	-2	hSpCas9	negative selection	5220519
26190782	26190804	1	-	27760321	HT29	viability after 13 days	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.3376272429276095	[1172,915]	[1334,1675,1579]	4	hSpCas9	negative selection	5220520
26190825	26190847	1	+	27760321	HT29	viability after 13 days	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	0.4383061152359744	[149,116]	[174,353,106]	5	hSpCas9	negative selection	5220521
26197995	26198017	1	-	27760321	HT29	viability after 13 days	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.3698244413233499	[742,579]	[1424,901,666]	5	hSpCas9	negative selection	5220522
26198293	26198315	1	-	27760321	HT29	viability after 13 days	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	0.2249682716086432	[36,28]	[92,27,14]	3	hSpCas9	negative selection	5220523
26190706	26190728	1	+	27760321	HT29	viability after 10 days	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.1983698702119127	[331,258]	[441,336,486]	2	hSpCas9	negative selection	5303982
26190782	26190804	1	-	27760321	HT29	viability after 10 days	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.48535791788181837	[1172,915]	[1704,2121,1661]	6	hSpCas9	negative selection	5303983
26190825	26190847	1	+	27760321	HT29	viability after 10 days	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	-0.7169072249411332	[149,116]	[97,138,68]	-7	hSpCas9	negative selection	5303984
26197995	26198017	1	-	27760321	HT29	viability after 10 days	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.21370516018880703	[742,579]	[818,974,1076]	3	hSpCas9	negative selection	5303985
26198293	26198315	1	-	27760321	HT29	viability after 10 days	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	-0.9621963830468512	[36,28]	[0,20,40]	-7	hSpCas9	negative selection	5303986
26190706	26190728	1	+	27760321	MOLM13	viability	GACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.9942127194101213	[387,331]	[808,57]	7	hSpCas9	negative selection	5387445
26190782	26190804	1	-	27760321	MOLM13	viability	TGCTCCTCTGGCCGACCGTAGG	CATSPER4	ENSG00000188782	0.771673834472856	[1311,1172]	[1339,1071]	5	hSpCas9	negative selection	5387446
26190825	26190847	1	+	27760321	MOLM13	viability	AATCACGAACAAAGCGGTAAGG	CATSPER4	ENSG00000188782	0.024602957517883883	[174,149]	[173,23]	0	hSpCas9	negative selection	5387447
26197995	26198017	1	-	27760321	MOLM13	viability	ACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.3659337302930816	[956,742]	[792,460]	2	hSpCas9	negative selection	5387448
26198293	26198315	1	-	27760321	MOLM13	viability	AAGAGTGTTACTCCAAACACGG	CATSPER4	ENSG00000188782	-2.496170066813226	[47,36]	[7,0]	-8	hSpCas9	negative selection	5387449
26190632	26190655	1	+	27661255	K562	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	0.03263295226821672	[1566,2016]	[1672,1273]	1	dCas9-KRAB	negative selection	5468279
26190694	26190717	1	+	27661255	K562	viability	GGGACTCAGGAGGACCGTATGGG	CATSPER4	ENSG00000188782	0.025254738866889476	[698,943]	[755,585]	0	dCas9-KRAB	negative selection	5468280
26190845	26190868	1	+	27661255	K562	viability	GGATAGCTCTCGCCCCACAGTGG	CATSPER4	ENSG00000188782	0.00810430495599923	[422,320]	[275,320]	0	dCas9-KRAB	negative selection	5468281
26190766	26190789	1	+	27260156	BXPC3	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.003991388914101612	[633]	[606,763,565,722]	0	hSpCas9	negative selection	5533523
26190655	26190678	1	+	27260156	BXPC3	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.24071238076405488	[693]	[703,931,789,1029]	5	hSpCas9	negative selection	5533524
26191403	26191426	1	+	27260156	BXPC3	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.06472020596309891	[1564]	[1590,1751,1572,1955]	1	hSpCas9	negative selection	5533525
26191390	26191413	1	-	27260156	BXPC3	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.18721778313834392	[146]	[119,150,193,250]	4	hSpCas9	negative selection	5597801
26193825	26193848	1	+	27260156	BXPC3	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.4212246812038014	[1045]	[1281,1245,1626,1765]	8	hSpCas9	negative selection	5597802
26193809	26193832	1	-	27260156	BXPC3	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.40328629538730654	[299]	[258,242,242,193]	-7	hSpCas9	negative selection	5597803
26190766	26190789	1	+	27260156	A673	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.05115362074689461	[633]	[766,782,779,822]	1	hSpCas9	negative selection	5654774
26190655	26190678	1	+	27260156	A673	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.2716802905403418	[693]	[1052,909,933,1140]	6	hSpCas9	negative selection	5654775
26191403	26191426	1	+	27260156	A673	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.2474442055550128	[1564]	[2518,2130,2231,2062]	6	hSpCas9	negative selection	5654776
26191390	26191413	1	-	27260156	A673	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.23007201696941282	[146]	[200,170,241,213]	5	hSpCas9	negative selection	5719052
26193825	26193848	1	+	27260156	A673	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.46165492224060767	[1045]	[1834,1595,1656,1849]	9	hSpCas9	negative selection	5719053
26193809	26193832	1	-	27260156	A673	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.1386338064822109	[299]	[329,281,330,368]	-3	hSpCas9	negative selection	5719054
26190766	26190789	1	+	27260156	A375	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.1330858149881043	[633]	[869,834,872,685]	2	hSpCas9	negative selection	5776025
26190655	26190678	1	+	27260156	A375	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.4174814709669943	[693]	[1254,1285,909,923]	6	hSpCas9	negative selection	5776026
26191403	26191426	1	+	27260156	A375	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.1361917857407493	[1564]	[1890,2062,2151,1936]	2	hSpCas9	negative selection	5776027
26191390	26191413	1	-	27260156	A375	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.325084537707107	[146]	[360,208,187,113]	5	hSpCas9	negative selection	5840303
26193825	26193848	1	+	27260156	A375	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.7096445040523904	[1045]	[1882,2709,1940,1596]	9	hSpCas9	negative selection	5840304
26193809	26193832	1	-	27260156	A375	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.05739558608490558	[299]	[438,284,433,197]	-1	hSpCas9	negative selection	5840305
26190766	26190789	1	+	27260156	COLO741	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.23803218809608345	[633]	[1088,857,929]	5	hSpCas9	negative selection	5897276
26190655	26190678	1	+	27260156	COLO741	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.2713319181362053	[693]	[1228,1139,867]	6	hSpCas9	negative selection	5897277
26191403	26191426	1	+	27260156	COLO741	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.1637751619247001	[1564]	[2454,2347,1951]	3	hSpCas9	negative selection	5897278
26191390	26191413	1	-	27260156	COLO741	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.5221191036766883	[146]	[315,248,248]	9	hSpCas9	negative selection	5961554
26193825	26193848	1	+	27260156	COLO741	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.464801122495053	[1045]	[1669,1986,1856]	8	hSpCas9	negative selection	5961555
26193809	26193832	1	-	27260156	COLO741	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.15575400087833446	[299]	[377,349,308]	-3	hSpCas9	negative selection	5961556
26190766	26190789	1	+	27260156	CAL120	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.12282157519198494	[633]	[524,1056,942]	1	hSpCas9	negative selection	6018527
26190655	26190678	1	+	27260156	CAL120	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.3165666744884613	[693]	[1047,1046,1125]	5	hSpCas9	negative selection	6018528
26191403	26191426	1	+	27260156	CAL120	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.39187838104597716	[1564]	[2526,2773,2362]	6	hSpCas9	negative selection	6018529
26191390	26191413	1	-	27260156	CAL120	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.1882884973166956	[146]	[165,254,197]	3	hSpCas9	negative selection	6082805
26193825	26193848	1	+	27260156	CAL120	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.6750875570874928	[1045]	[2598,1892,1824]	8	hSpCas9	negative selection	6082806
26193809	26193832	1	-	27260156	CAL120	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.3666089710403263	[299]	[334,230,308]	-5	hSpCas9	negative selection	6082807
26190766	26190789	1	+	27260156	CADOES1	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.1755248525254226	[633]	[403,576,606,499]	-3	hSpCas9	negative selection	6139778
26190655	26190678	1	+	27260156	CADOES1	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.09738507068564395	[693]	[695,618,678,770]	1	hSpCas9	negative selection	6139779
26191403	26191426	1	+	27260156	CADOES1	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.24717754985112306	[1564]	[1704,1836,1628,1739]	4	hSpCas9	negative selection	6139780
26191390	26191413	1	-	27260156	CADOES1	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.19768894088578248	[146]	[165,112,141,207]	3	hSpCas9	negative selection	6204056
26193825	26193848	1	+	27260156	CADOES1	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.579543145169499	[1045]	[1513,1276,1508,1516]	8	hSpCas9	negative selection	6204057
26193809	26193832	1	-	27260156	CADOES1	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.4619105909953788	[299]	[198,162,250,196]	-7	hSpCas9	negative selection	6204058
26190766	26190789	1	+	27260156	EWS502	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.08156841928842823	[633]	[807,662,675,679]	1	hSpCas9	negative selection	6261029
26190655	26190678	1	+	27260156	EWS502	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.42801245820328415	[693]	[751,1038,1066,1131]	7	hSpCas9	negative selection	6261030
26191403	26191426	1	+	27260156	EWS502	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.33029138166033256	[1564]	[2051,1750,2140,2426]	6	hSpCas9	negative selection	6261031
26191390	26191413	1	-	27260156	EWS502	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.2767537836320484	[146]	[214,109,296,128]	5	hSpCas9	negative selection	6325307
26193825	26193848	1	+	27260156	EWS502	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.6713809158695987	[1045]	[1381,1765,1823,2153]	9	hSpCas9	negative selection	6325308
26193809	26193832	1	-	27260156	EWS502	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.16263361046252833	[299]	[292,264,198,382]	-3	hSpCas9	negative selection	6325309
26190766	26190789	1	+	27260156	EW8	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.07017348454570588	[633]	[596,606,401,579]	1	hSpCas9	negative selection	6382280
26190655	26190678	1	+	27260156	EW8	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.33079142293927255	[693]	[723,964,444,740]	6	hSpCas9	negative selection	6382281
26191403	26191426	1	+	27260156	EW8	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.2339252001461194	[1564]	[1748,1594,1255,1430]	4	hSpCas9	negative selection	6382282
26191390	26191413	1	-	27260156	EW8	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	-0.058097285260226394	[146]	[171,98,82,114]	-1	hSpCas9	negative selection	6446558
26193825	26193848	1	+	27260156	EW8	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.7623908117188563	[1045]	[1783,1571,1177,1296]	9	hSpCas9	negative selection	6446559
26193809	26193832	1	-	27260156	EW8	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.0784902961196352	[299]	[308,260,172,195]	-1	hSpCas9	negative selection	6446560
26190766	26190789	1	+	27260156	CORL105	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.2841419680850567	[633]	[827,970,1010,817]	5	hSpCas9	negative selection	6503531
26190655	26190678	1	+	27260156	CORL105	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.7464724278379506	[693]	[1285,1286,1669,1255]	9	hSpCas9	negative selection	6503532
26191403	26191426	1	+	27260156	CORL105	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.3153507448522288	[1564]	[2358,2296,2492,2005]	6	hSpCas9	negative selection	6503533
26191390	26191413	1	-	27260156	CORL105	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.09647993432416202	[146]	[145,178,211,201]	1	hSpCas9	negative selection	6567809
26193825	26193848	1	+	27260156	CORL105	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.6490788776104968	[1045]	[1868,1993,2105,1737]	9	hSpCas9	negative selection	6567810
26193809	26193832	1	-	27260156	CORL105	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	0.14571124582278927	[299]	[327,349,411,465]	2	hSpCas9	negative selection	6567811
26190766	26190789	1	+	27260156	HS294T	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.2482343987450803	[633]	[248,283,243,410]	3	hSpCas9	negative selection	6624782
26190655	26190678	1	+	27260156	HS294T	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.8386344719444312	[693]	[353,422,390,820]	9	hSpCas9	negative selection	6624783
26191403	26191426	1	+	27260156	HS294T	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.26841836544154507	[1564]	[593,789,600,980]	3	hSpCas9	negative selection	6624784
26191390	26191413	1	-	27260156	HS294T	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.6350037735099066	[146]	[105,58,93,93]	8	hSpCas9	negative selection	6689060
26193825	26193848	1	+	27260156	HS294T	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.44146494549886217	[1045]	[433,463,827,469]	6	hSpCas9	negative selection	6689061
26193809	26193832	1	-	27260156	HS294T	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.032140406143596145	[299]	[115,143,78,112]	0	hSpCas9	negative selection	6689062
26190766	26190789	1	+	27260156	HCC44	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.0432764900651717	[633]	[948,669,606,729]	0	hSpCas9	negative selection	6746033
26190655	26190678	1	+	27260156	HCC44	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.3648700526230364	[693]	[1062,1072,1001,894]	6	hSpCas9	negative selection	6746034
26191403	26191426	1	+	27260156	HCC44	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.08378052057050622	[1564]	[2328,1486,2215,1619]	1	hSpCas9	negative selection	6746035
26191390	26191413	1	-	27260156	HCC44	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.68477692599074	[146]	[267,203,238,356]	9	hSpCas9	negative selection	6810311
26193825	26193848	1	+	27260156	HCC44	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.7328625963736892	[1045]	[1840,1739,2294,2046]	9	hSpCas9	negative selection	6810312
26193809	26193832	1	-	27260156	HCC44	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	0.12100298336403637	[299]	[320,461,286,370]	2	hSpCas9	negative selection	6810313
26190766	26190789	1	+	27260156	G402	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.132264877689447	[633]	[832,907,1190,475]	1	hSpCas9	negative selection	6867284
26190655	26190678	1	+	27260156	G402	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.37838081378767496	[693]	[1588,770,901,1183]	5	hSpCas9	negative selection	6867285
26191403	26191426	1	+	27260156	G402	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.32924718024912236	[1564]	[2531,2582,2395,2119]	4	hSpCas9	negative selection	6867286
26191390	26191413	1	-	27260156	G402	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.3558021284823234	[146]	[145,332,176,253]	4	hSpCas9	negative selection	6931562
26193825	26193848	1	+	27260156	G402	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.4949494760662103	[1045]	[2207,2024,1523,1516]	6	hSpCas9	negative selection	6931563
26193809	26193832	1	-	27260156	G402	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.6982714538272251	[299]	[216,165,227,282]	-7	hSpCas9	negative selection	6931564
26190766	26190789	1	+	27260156	L33	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.12263655767300724	[633]	[602,202,378,626]	-3	hSpCas9	negative selection	6988535
26190655	26190678	1	+	27260156	L33	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.46170314764497156	[693]	[1008,417,474,1034]	8	hSpCas9	negative selection	6988536
26191403	26191426	1	+	27260156	L33	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.12934823795670636	[1564]	[1779,692,1090,1638]	3	hSpCas9	negative selection	6988537
26191390	26191413	1	-	27260156	L33	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.2778038570235748	[146]	[225,68,110,140]	6	hSpCas9	negative selection	7052813
26193825	26193848	1	+	27260156	L33	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.5012947670658128	[1045]	[1483,633,941,1392]	8	hSpCas9	negative selection	7052814
26193809	26193832	1	-	27260156	L33	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.17875643140397446	[299]	[260,111,184,231]	-4	hSpCas9	negative selection	7052815
26190766	26190789	1	+	27260156	K562	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.6393877385342899	[633]	[875,1061,861,728]	7	hSpCas9	negative selection	7109786
26190655	26190678	1	+	27260156	K562	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.4758310018038192	[693]	[748,635,1518,535]	6	hSpCas9	negative selection	7109787
26191403	26191426	1	+	27260156	K562	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	-0.08670652344484475	[1564]	[1468,1132,1454,1186]	-1	hSpCas9	negative selection	7109788
26191390	26191413	1	-	27260156	K562	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	-0.42899478897977206	[146]	[131,22,160,72]	-5	hSpCas9	negative selection	7174064
26193825	26193848	1	+	27260156	K562	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.39079369369770145	[1045]	[1461,1220,1348,889]	5	hSpCas9	negative selection	7174065
26193809	26193832	1	-	27260156	K562	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.7788532187770557	[299]	[173,161,225,69]	-7	hSpCas9	negative selection	7174066
26190766	26190789	1	+	27260156	HT29	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.2061518418022163	[633]	[1096,1016,790,695]	4	hSpCas9	negative selection	7231037
26190655	26190678	1	+	27260156	HT29	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.35587045624534674	[693]	[1324,1146,1013,874]	7	hSpCas9	negative selection	7231038
26191403	26191426	1	+	27260156	HT29	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.2922712808353114	[1564]	[2742,2494,2124,2022]	6	hSpCas9	negative selection	7231039
26191390	26191413	1	-	27260156	HT29	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.19438545489297576	[146]	[340,204,139,147]	4	hSpCas9	negative selection	7295315
26193825	26193848	1	+	27260156	HT29	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.5409827778873864	[1045]	[1597,2381,1888,1577]	9	hSpCas9	negative selection	7295316
26193809	26193832	1	-	27260156	HT29	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.16942276977761417	[299]	[387,391,268,263]	-3	hSpCas9	negative selection	7295317
26190766	26190789	1	+	27260156	MHHES1	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.3648909871646923	[633]	[1362,1082,705,639]	6	hSpCas9	negative selection	7352288
26190655	26190678	1	+	27260156	MHHES1	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.21425449111196593	[693]	[883,965,1004,783]	4	hSpCas9	negative selection	7352289
26191403	26191426	1	+	27260156	MHHES1	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.35552130250493974	[1564]	[2297,2516,2612,1704]	6	hSpCas9	negative selection	7352290
26191390	26191413	1	-	27260156	MHHES1	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.28550259563024283	[146]	[190,372,210,73]	5	hSpCas9	negative selection	7416566
26193825	26193848	1	+	27260156	MHHES1	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.40030946744770546	[1045]	[1979,1812,1200,1319]	7	hSpCas9	negative selection	7416567
26193809	26193832	1	-	27260156	MHHES1	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	0.11320082552120514	[299]	[331,384,493,264]	2	hSpCas9	negative selection	7416568
26190766	26190789	1	+	27260156	MEWO	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.26506887433276993	[633]	[695,468,354]	-5	hSpCas9	negative selection	7473539
26190655	26190678	1	+	27260156	MEWO	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.1211640649898208	[693]	[732,610,779]	2	hSpCas9	negative selection	7473540
26191403	26191426	1	+	27260156	MEWO	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.2820312399306899	[1564]	[2143,1347,1920]	6	hSpCas9	negative selection	7473541
26191390	26191413	1	-	27260156	MEWO	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.21123631086849204	[146]	[156,194,124]	4	hSpCas9	negative selection	7537817
26193825	26193848	1	+	27260156	MEWO	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.5019562852135195	[1045]	[1661,1317,1230]	8	hSpCas9	negative selection	7537818
26193809	26193832	1	-	27260156	MEWO	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.4900567148740954	[299]	[248,196,162]	-8	hSpCas9	negative selection	7537819
26190766	26190789	1	+	27260156	LNCAPCLONEFGC	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.05322962421377003	[633]	[886,416,606,479]	0	hSpCas9	negative selection	7594790
26190655	26190678	1	+	27260156	LNCAPCLONEFGC	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.21089042716198692	[693]	[826,704,750,629]	3	hSpCas9	negative selection	7594791
26191403	26191426	1	+	27260156	LNCAPCLONEFGC	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.5853618316615115	[1564]	[1882,1928,2694,2101]	8	hSpCas9	negative selection	7594792
26191390	26191413	1	-	27260156	LNCAPCLONEFGC	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.32959322961659643	[146]	[169,155,187,158]	5	hSpCas9	negative selection	7659068
26193825	26193848	1	+	27260156	LNCAPCLONEFGC	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.8099255128632994	[1045]	[1668,1463,2265,1346]	9	hSpCas9	negative selection	7659069
26193809	26193832	1	-	27260156	LNCAPCLONEFGC	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	0.3165479613705486	[299]	[208,204,507,467]	5	hSpCas9	negative selection	7659070
26190766	26190789	1	+	27260156	PANC0327	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.060410496352413356	[633]	[342,750,601,420]	-1	hSpCas9	negative selection	7716041
26190655	26190678	1	+	27260156	PANC0327	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.5842725256800316	[693]	[1267,724,992,764]	8	hSpCas9	negative selection	7716042
26191403	26191426	1	+	27260156	PANC0327	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	-0.014119734608469159	[1564]	[1427,1175,1279,1651]	0	hSpCas9	negative selection	7716043
26191390	26191413	1	-	27260156	PANC0327	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.26581425235429457	[146]	[151,190,82,196]	4	hSpCas9	negative selection	7780319
26193825	26193848	1	+	27260156	PANC0327	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.7028309226191625	[1045]	[1395,1626,1577,1423]	8	hSpCas9	negative selection	7780320
26193809	26193832	1	-	27260156	PANC0327	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	0.081523952424007	[299]	[405,289,251,188]	1	hSpCas9	negative selection	7780321
26190766	26190789	1	+	27260156	NCIH2009	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.022224647864093616	[633]	[1247,788,730]	0	hSpCas9	negative selection	7837292
26190655	26190678	1	+	27260156	NCIH2009	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.6453670207464335	[693]	[1506,1428,1610]	8	hSpCas9	negative selection	7837293
26191403	26191426	1	+	27260156	NCIH2009	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.4406451636228552	[1564]	[3194,2842,2906]	6	hSpCas9	negative selection	7837294
26191390	26191413	1	-	27260156	NCIH2009	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.16798232314355732	[146]	[252,298,142]	2	hSpCas9	negative selection	7901570
26193825	26193848	1	+	27260156	NCIH2009	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.5834639953383227	[1045]	[2811,2070,1807]	7	hSpCas9	negative selection	7901571
26193809	26193832	1	-	27260156	NCIH2009	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	0.057422529227800445	[299]	[379,251,667]	0	hSpCas9	negative selection	7901572
26190766	26190789	1	+	27260156	NCIH1373	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.2205922718769463	[633]	[1110,352,412,176]	-2	hSpCas9	negative selection	7958543
26190655	26190678	1	+	27260156	NCIH1373	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.4061913504590414	[693]	[1207,895,1206,218]	4	hSpCas9	negative selection	7958544
26191403	26191426	1	+	27260156	NCIH1373	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.6149651705348882	[1564]	[3359,1475,2810,882]	6	hSpCas9	negative selection	7958545
26191390	26191413	1	-	27260156	NCIH1373	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.7331138187860953	[146]	[300,166,190,121]	7	hSpCas9	negative selection	8022821
26193825	26193848	1	+	27260156	NCIH1373	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.509497154905395	[1045]	[1954,1446,1708,425]	5	hSpCas9	negative selection	8022822
26193809	26193832	1	-	27260156	NCIH1373	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.6840178247859011	[299]	[330,74,228,61]	-6	hSpCas9	negative selection	8022823
26190766	26190789	1	+	27260156	PATU8902	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.044443097390826636	[633]	[544,875,988,1249]	0	hSpCas9	negative selection	8079794
26190655	26190678	1	+	27260156	PATU8902	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.5387246656879208	[693]	[1443,1836,965,1481]	5	hSpCas9	negative selection	8079795
26191403	26191426	1	+	27260156	PATU8902	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.6163075337436847	[1564]	[3466,3327,3138,3469]	6	hSpCas9	negative selection	8079796
26191390	26191413	1	-	27260156	PATU8902	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.5356452245650893	[146]	[221,526,164,307]	5	hSpCas9	negative selection	8144072
26193825	26193848	1	+	27260156	PATU8902	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.7687243035375195	[1045]	[2575,2389,2428,2530]	7	hSpCas9	negative selection	8144073
26193809	26193832	1	-	27260156	PATU8902	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	0.39847544855841344	[299]	[480,629,241,977]	4	hSpCas9	negative selection	8144074
26190766	26190789	1	+	27260156	PANC1	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.1554781753960175	[633]	[560,492,462,437]	-3	hSpCas9	negative selection	8201045
26190655	26190678	1	+	27260156	PANC1	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.3113861527809212	[693]	[755,747,800,656]	5	hSpCas9	negative selection	8201046
26191403	26191426	1	+	27260156	PANC1	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.0093609187428918	[1564]	[1372,1710,1449,989]	0	hSpCas9	negative selection	8201047
26191390	26191413	1	-	27260156	PANC1	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	-0.01563001842422218	[146]	[124,138,102,131]	0	hSpCas9	negative selection	8265323
26193825	26193848	1	+	27260156	PANC1	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.536408851146104	[1045]	[1370,1696,1250,1000]	8	hSpCas9	negative selection	8265324
26193809	26193832	1	-	27260156	PANC1	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.20615016706183042	[299]	[186,310,363,72]	-3	hSpCas9	negative selection	8265325
26190766	26190789	1	+	27260156	PANC0813	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.08645619330538845	[633]	[625,1008,594,573]	-1	hSpCas9	negative selection	8322296
26190655	26190678	1	+	27260156	PANC0813	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.5368454953075268	[693]	[1307,954,1156,1312]	8	hSpCas9	negative selection	8322297
26191403	26191426	1	+	27260156	PANC0813	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.2092090015460284	[1564]	[2080,1879,2482,2054]	3	hSpCas9	negative selection	8322298
26191390	26191413	1	-	27260156	PANC0813	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.49693078312657346	[146]	[252,174,260,283]	7	hSpCas9	negative selection	8386574
26193825	26193848	1	+	27260156	PANC0813	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.5086116850508919	[1045]	[1852,1900,1640,1610]	7	hSpCas9	negative selection	8386575
26193809	26193832	1	-	27260156	PANC0813	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.08618547254179454	[299]	[380,352,325,274]	-1	hSpCas9	negative selection	8386576
26190766	26190789	1	+	27260156	RDES	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.26651948200377995	[633]	[577,556,615,674]	-4	hSpCas9	negative selection	8443547
26190655	26190678	1	+	27260156	RDES	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.0738873368699523	[693]	[642,745,958,1080]	1	hSpCas9	negative selection	8443548
26191403	26191426	1	+	27260156	RDES	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.10157476291906486	[1564]	[1594,1858,2141,2196]	1	hSpCas9	negative selection	8443549
26191390	26191413	1	-	27260156	RDES	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.20989851317192332	[146]	[133,209,232,215]	3	hSpCas9	negative selection	8507825
26193825	26193848	1	+	27260156	RDES	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.435483468298282	[1045]	[1442,1609,1677,1791]	7	hSpCas9	negative selection	8507826
26193809	26193832	1	-	27260156	RDES	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.24681225342372137	[299]	[203,233,300,467]	-4	hSpCas9	negative selection	8507827
26190766	26190789	1	+	27260156	PC3	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.21913072647422732	[633]	[545,586,1069,884]	5	hSpCas9	negative selection	8564798
26190655	26190678	1	+	27260156	PC3	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.3105571278623821	[693]	[598,745,1214,1046]	6	hSpCas9	negative selection	8564799
26191403	26191426	1	+	27260156	PC3	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.2607840725111852	[1564]	[957,1949,2946,2300]	5	hSpCas9	negative selection	8564800
26191390	26191413	1	-	27260156	PC3	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.34794757816995925	[146]	[144,183,200,218]	7	hSpCas9	negative selection	8629076
26193825	26193848	1	+	27260156	PC3	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.617258492566606	[1045]	[1079,1270,2776,1819]	9	hSpCas9	negative selection	8629077
26193809	26193832	1	-	27260156	PC3	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	0.0844982032416347	[299]	[267,269,381,358]	2	hSpCas9	negative selection	8629078
26190766	26190789	1	+	27260156	PATU8988T	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.46635658339751157	[633]	[900,961,674,861]	7	hSpCas9	negative selection	8686049
26190655	26190678	1	+	27260156	PATU8988T	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.4917156766779538	[693]	[757,1063,781,1201]	8	hSpCas9	negative selection	8686050
26191403	26191426	1	+	27260156	PATU8988T	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.19817936830775973	[1564]	[1742,1813,1371,2047]	3	hSpCas9	negative selection	8686051
26191390	26191413	1	-	27260156	PATU8988T	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.8073827060695131	[146]	[252,307,304,122]	9	hSpCas9	negative selection	8750327
26193825	26193848	1	+	27260156	PATU8988T	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.504552743608599	[1045]	[1449,1510,1376,1402]	8	hSpCas9	negative selection	8750328
26193809	26193832	1	-	27260156	PATU8988T	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.0033521019778426364	[299]	[243,498,257,165]	0	hSpCas9	negative selection	8750329
26190766	26190789	1	+	27260156	T47D	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.031066654891208467	[633]	[721,686,768,848]	0	hSpCas9	negative selection	8807300
26190655	26190678	1	+	27260156	T47D	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.2937930957293382	[693]	[965,867,928,1219]	6	hSpCas9	negative selection	8807301
26191403	26191426	1	+	27260156	T47D	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.27742274146197676	[1564]	[2357,2063,2168,2262]	6	hSpCas9	negative selection	8807302
26191390	26191413	1	-	27260156	T47D	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.12785232343938358	[146]	[190,167,159,232]	2	hSpCas9	negative selection	8871578
26193825	26193848	1	+	27260156	T47D	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.7015326713570214	[1045]	[2077,1628,1974,2284]	9	hSpCas9	negative selection	8871579
26193809	26193832	1	-	27260156	T47D	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.09663426564310218	[299]	[251,361,389,297]	-2	hSpCas9	negative selection	8871580
26190766	26190789	1	+	27260156	SU8686	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.13281866984597585	[633]	[552,699,631,915]	2	hSpCas9	negative selection	8928551
26190655	26190678	1	+	27260156	SU8686	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.5229316125687353	[693]	[965,786,1067,1189]	8	hSpCas9	negative selection	8928552
26191403	26191426	1	+	27260156	SU8686	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.38245559538757323	[1564]	[1740,1696,2521,2238]	6	hSpCas9	negative selection	8928553
26191390	26191413	1	-	27260156	SU8686	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.5386810558357438	[146]	[194,139,208,331]	8	hSpCas9	negative selection	8992829
26193825	26193848	1	+	27260156	SU8686	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.4952096228040914	[1045]	[1291,1140,1574,1975]	8	hSpCas9	negative selection	8992830
26193809	26193832	1	-	27260156	SU8686	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.6131931614082952	[299]	[183,179,203,214]	-7	hSpCas9	negative selection	8992831
26190766	26190789	1	+	27260156	SKES1	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.052173876127396324	[633]	[888,606,493,496]	-1	hSpCas9	negative selection	9049802
26190655	26190678	1	+	27260156	SKES1	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.3341398706593851	[693]	[1033,931,625,916]	7	hSpCas9	negative selection	9049803
26191403	26191426	1	+	27260156	SKES1	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.3137051845387324	[1564]	[2024,2153,1913,1712]	6	hSpCas9	negative selection	9049804
26191390	26191413	1	-	27260156	SKES1	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.4398635499635182	[146]	[222,291,173,127]	8	hSpCas9	negative selection	9114080
26193825	26193848	1	+	27260156	SKES1	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.5445719667826454	[1045]	[1922,1843,1265,1177]	9	hSpCas9	negative selection	9114081
26193809	26193832	1	-	27260156	SKES1	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.026303720333168634	[299]	[202,532,240,220]	0	hSpCas9	negative selection	9114082
26190766	26190789	1	+	27260156	TOV112D	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.027687916983850702	[633]	[660,708,557,587]	0	hSpCas9	negative selection	9171053
26190655	26190678	1	+	27260156	TOV112D	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.3116879260528568	[693]	[989,980,901,622]	6	hSpCas9	negative selection	9171054
26191403	26191426	1	+	27260156	TOV112D	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.23316907547655363	[1564]	[2069,2052,1600,1716]	4	hSpCas9	negative selection	9171055
26191390	26191413	1	-	27260156	TOV112D	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	-0.20788733384458946	[146]	[73,170,183,87]	-4	hSpCas9	negative selection	9235331
26193825	26193848	1	+	27260156	TOV112D	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.596053150417295	[1045]	[1604,1799,1300,1677]	9	hSpCas9	negative selection	9235332
26193809	26193832	1	-	27260156	TOV112D	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.42094554743025137	[299]	[164,193,306,218]	-7	hSpCas9	negative selection	9235333
26190766	26190789	1	+	27260156	TC71	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	-0.06923322008758281	[633]	[659,625,670,631]	-2	hSpCas9	negative selection	9292304
26190655	26190678	1	+	27260156	TC71	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.13192845728951041	[693]	[752,861,775,875]	3	hSpCas9	negative selection	9292305
26191403	26191426	1	+	27260156	TC71	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.30186675227629367	[1564]	[1819,1944,2158,2368]	7	hSpCas9	negative selection	9292306
26191390	26191413	1	-	27260156	TC71	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.42684345128905776	[146]	[137,178,251,282]	8	hSpCas9	negative selection	9356582
26193825	26193848	1	+	27260156	TC71	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.5568769244855891	[1045]	[1669,1682,1555,1693]	9	hSpCas9	negative selection	9356583
26193809	26193832	1	-	27260156	TC71	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.3852635158231851	[299]	[222,197,246,321]	-8	hSpCas9	negative selection	9356584
26190766	26190789	1	+	27260156	TC32	viability	AGTACCATTCACGAGTCCTACGG	CATSPER4	ENSG00000188782	0.12695095854384258	[633]	[691,610,612,645]	2	hSpCas9	negative selection	9413555
26190655	26190678	1	+	27260156	TC32	viability	CAGCAATGGACCTCCCATACAGG	CATSPER4	ENSG00000188782	0.17314768209897102	[693]	[677,496,948,919]	3	hSpCas9	negative selection	9413556
26191403	26191426	1	+	27260156	TC32	viability	TCTCCGTACCAACTCCTACCTGG	CATSPER4	ENSG00000188782	0.38205093346459895	[1564]	[1691,1494,2623,2059]	6	hSpCas9	negative selection	9413557
26191390	26191413	1	-	27260156	TC32	viability	GGTACGGAGAGCGATGGTGATGG	CATSPER4	ENSG00000188782	0.18258120879610074	[146]	[167,92,214,175]	3	hSpCas9	negative selection	9477833
26193825	26193848	1	+	27260156	TC32	viability	GCTGACCATCCTTCTTTGTGAGG	CATSPER4	ENSG00000188782	0.6218810504162147	[1045]	[1561,1077,2066,1506]	9	hSpCas9	negative selection	9477834
26193809	26193832	1	-	27260156	TC32	viability	GGTCAGCACAATGTCATCTATGG	CATSPER4	ENSG00000188782	-0.13644307913933418	[299]	[198,236,318,281]	-2	hSpCas9	negative selection	9477835
26190665	26190688	1	+	27869803	HPAFII	viability after 27 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.9512317224403487	[208]	[8,381,NaN]	7	hSpCas9	negative selection	9533389
26191369	26191392	1	-	27869803	HPAFII	viability after 27 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	1.7996054224526694	[248]	[656,287,NaN]	9	hSpCas9	negative selection	9533390
26197996	26198019	1	-	27869803	HPAFII	viability after 27 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.31680798469235616	[604]	[531,282,NaN]	2	hSpCas9	negative selection	9533391
26200007	26200030	1	+	27869803	HPAFII	viability after 27 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.08944269346661038	[123]	[33,83,NaN]	0	hSpCas9	negative selection	9533392
26200859	26200882	1	-	27869803	HPAFII	viability after 27 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.15524107598244072	[283]	[126,198,NaN]	1	hSpCas9	negative selection	9533393
26201413	26201436	1	+	27869803	HPAFII	viability after 27 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	-0.7522412326868939	[29]	[16,2,NaN]	-5	hSpCas9	negative selection	9533394
26190665	26190688	1	+	27869803	HPAFII	viability after 15 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.849368064940059	[208]	[207,526,NaN]	8	hSpCas9	negative selection	9615838
26191369	26191392	1	-	27869803	HPAFII	viability after 15 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.5129253809074885	[248]	[490,313,NaN]	6	hSpCas9	negative selection	9615839
26197996	26198019	1	-	27869803	HPAFII	viability after 15 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.23684420108633497	[604]	[1121,544,NaN]	2	hSpCas9	negative selection	9615840
26200007	26200030	1	+	27869803	HPAFII	viability after 15 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	0.335026548508658	[123]	[193,151,NaN]	4	hSpCas9	negative selection	9615841
26200859	26200882	1	-	27869803	HPAFII	viability after 15 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.004109560373617538	[283]	[357,270,NaN]	0	hSpCas9	negative selection	9615842
26201413	26201436	1	+	27869803	HPAFII	viability after 15 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	-0.5545648908575584	[29]	[45,6,NaN]	-5	hSpCas9	negative selection	9615843
26190665	26190688	1	+	27869803	ASPC1	viability after 36 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.8618608525912669	[487]	[287,187,417]	8	hSpCas9	negative selection	9698287
26191369	26191392	1	-	27869803	ASPC1	viability after 36 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.7568059109227059	[496]	[474,289,164]	7	hSpCas9	negative selection	9698288
26197996	26198019	1	-	27869803	ASPC1	viability after 36 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.1407977472516666	[1434]	[654,451,553]	1	hSpCas9	negative selection	9698289
26200007	26200030	1	+	27869803	ASPC1	viability after 36 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	-0.9549177588113641	[434]	[99,16,110]	-7	hSpCas9	negative selection	9698290
26200859	26200882	1	-	27869803	ASPC1	viability after 36 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	1.073396262817956	[799]	[950,566,342]	8	hSpCas9	negative selection	9698291
26201413	26201436	1	+	27869803	ASPC1	viability after 36 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	-4.308402661582923	[56]	[0,0,0]	-9	hSpCas9	negative selection	9698292
26190665	26190688	1	+	27869803	PATU8988S	viability after 35 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	-0.3874881649451688	[431]	[135,129,NaN]	-4	hSpCas9	negative selection	9780736
26191369	26191392	1	-	27869803	PATU8988S	viability after 35 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	0.13830399899941606	[551]	[325,162,NaN]	1	hSpCas9	negative selection	9780737
26197996	26198019	1	-	27869803	PATU8988S	viability after 35 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.7243054290715567	[1255]	[714,956,NaN]	7	hSpCas9	negative selection	9780738
26200007	26200030	1	+	27869803	PATU8988S	viability after 35 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	1.2344505204432425	[383]	[316,410,NaN]	9	hSpCas9	negative selection	9780739
26200859	26200882	1	-	27869803	PATU8988S	viability after 35 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.019825714772213468	[590]	[355,112,NaN]	0	hSpCas9	negative selection	9780740
26201413	26201436	1	+	27869803	PATU8988S	viability after 35 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	-2.0118584602757426	[49]	[1,7,NaN]	-9	hSpCas9	negative selection	9780741
26190665	26190688	1	+	27869803	PATU8988S	viability after 31 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	-0.3845467380108082	[431]	[94,178,NaN]	-4	hSpCas9	negative selection	9863185
26191369	26191392	1	-	27869803	PATU8988S	viability after 31 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	-0.35584957135899886	[551]	[138,213,NaN]	-4	hSpCas9	negative selection	9863186
26197996	26198019	1	-	27869803	PATU8988S	viability after 31 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.7534533093114579	[1255]	[732,985,NaN]	8	hSpCas9	negative selection	9863187
26200007	26200030	1	+	27869803	PATU8988S	viability after 31 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	0.9216168199448616	[383]	[293,284,NaN]	8	hSpCas9	negative selection	9863188
26200859	26200882	1	-	27869803	PATU8988S	viability after 31 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	-0.036764914669053836	[590]	[267,180,NaN]	0	hSpCas9	negative selection	9863189
26201413	26201436	1	+	27869803	PATU8988S	viability after 31 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	-3.675759089180144	[49]	[1,0,NaN]	-9	hSpCas9	negative selection	9863190
26190665	26190688	1	+	27869803	HPAFII	viability after 35 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.8865852679758474	[208]	[6,407,NaN]	6	hSpCas9	negative selection	9945634
26191369	26191392	1	-	27869803	HPAFII	viability after 35 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	1.813326740174066	[248]	[609,254,NaN]	9	hSpCas9	negative selection	9945635
26197996	26198019	1	-	27869803	HPAFII	viability after 35 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.3111078098953113	[604]	[474,272,NaN]	2	hSpCas9	negative selection	9945636
26200007	26200030	1	+	27869803	HPAFII	viability after 35 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	0.8402788517550841	[123]	[70,158,NaN]	5	hSpCas9	negative selection	9945637
26200859	26200882	1	-	27869803	HPAFII	viability after 35 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	1.0452390662007427	[283]	[180,426,NaN]	7	hSpCas9	negative selection	9945638
26201413	26201436	1	+	27869803	HPAFII	viability after 35 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	-0.872309166013999	[29]	[12,2,NaN]	-5	hSpCas9	negative selection	9945639
26190665	26190688	1	+	27869803	HPAFII	viability after 31 days	CCTCCCATACAGGCCTCGAGGGG	CATSPER4	ENSG00000188782	0.7023614380108232	[208]	[8,388,NaN]	5	hSpCas9	negative selection	10028083
26191369	26191392	1	-	27869803	HPAFII	viability after 31 days	GGCATTGATCACCAGCAGCAGGG	CATSPER4	ENSG00000188782	1.887210336669136	[248]	[548,481,NaN]	9	hSpCas9	negative selection	10028084
26197996	26198019	1	-	27869803	HPAFII	viability after 31 days	TGACGCGGATGATCCGGGCGAGG	CATSPER4	ENSG00000188782	0.03960403827601011	[604]	[437,251,NaN]	0	hSpCas9	negative selection	10028085
26200007	26200030	1	+	27869803	HPAFII	viability after 31 days	AATGATGAAGGCAGGAGAGCAGG	CATSPER4	ENSG00000188782	0.7976122387249356	[123]	[41,206,NaN]	6	hSpCas9	negative selection	10028086
26200859	26200882	1	-	27869803	HPAFII	viability after 31 days	CACAATGCACCAGTGGCAGCTGG	CATSPER4	ENSG00000188782	0.43884550087294705	[283]	[138,299,NaN]	3	hSpCas9	negative selection	10028087
26201413	26201436	1	+	27869803	HPAFII	viability after 31 days	ACAGGCGCTCGTCGACGAGCGGG	CATSPER4	ENSG00000188782	-2.058144170046345	[29]	[4,2,NaN]	-8	hSpCas9	negative selection	10028088
26191396	26191419	1	-	28162770	P31FUJ	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	1.2129975486351523	[57]	[157]	9	hSpCas9	negative selection	10126368
26199946	26199969	1	-	28162770	P31FUJ	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	0.2336206811313764	[130]	[180]	2	hSpCas9	negative selection	10126369
26197969	26197992	1	+	28162770	P31FUJ	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	0.25262462275586284	[9]	[13]	2	hSpCas9	negative selection	10126370
26190632	26190655	1	+	28162770	P31FUJ	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.3615355185365813	[163]	[149]	-3	hSpCas9	negative selection	10126371
26190705	26190728	1	+	28162770	P31FUJ	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.10727132233051978	[175]	[191]	-1	hSpCas9	negative selection	10126372
26190722	26190745	1	+	28162770	P31FUJ	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.6826051218538989	[167]	[122]	-5	hSpCas9	negative selection	10126373
26193830	26193853	1	-	28162770	P31FUJ	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	0.2654486631134465	[79]	[112]	3	hSpCas9	negative selection	10126374
26197995	26198018	1	-	28162770	P31FUJ	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.47565872831054246	[70]	[59]	-4	hSpCas9	negative selection	10126375
26198011	26198034	1	-	28162770	P31FUJ	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	0.1720061625475786	[459]	[608]	1	hSpCas9	negative selection	10126376
26199887	26199910	1	+	28162770	P31FUJ	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	0.25658263632454636	[155]	[218]	2	hSpCas9	negative selection	10126377
26191396	26191419	1	-	28162770	TF1	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10295734
26199946	26199969	1	-	28162770	TF1	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[58]	1	hSpCas9	negative selection	10295735
26197969	26197992	1	+	28162770	TF1	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10295736
26190632	26190655	1	+	28162770	TF1	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[25]	1	hSpCas9	negative selection	10295737
26190705	26190728	1	+	28162770	TF1	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10295738
26190722	26190745	1	+	28162770	TF1	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10295739
26193830	26193853	1	-	28162770	TF1	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10295740
26197995	26198018	1	-	28162770	TF1	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10295741
26198011	26198034	1	-	28162770	TF1	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[435]	1	hSpCas9	negative selection	10295742
26199887	26199910	1	+	28162770	TF1	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10295743
26191396	26191419	1	-	28162770	SKM1	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	-0.9595052217719404	[21]	[19]	-6	hSpCas9	negative selection	10465100
26199946	26199969	1	-	28162770	SKM1	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-0.880895387075574	[24]	[23]	-6	hSpCas9	negative selection	10465101
26197969	26197992	1	+	28162770	SKM1	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	-3.6293566200796095	[6]	[0]	-9	hSpCas9	negative selection	10465102
26190632	26190655	1	+	28162770	SKM1	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.9289169019385176	[41]	[38]	-6	hSpCas9	negative selection	10465103
26190705	26190728	1	+	28162770	SKM1	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.08780049300641635	[32]	[61]	0	hSpCas9	negative selection	10465104
26190722	26190745	1	+	28162770	SKM1	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.9948382948842212	[61]	[54]	-6	hSpCas9	negative selection	10465105
26193830	26193853	1	-	28162770	SKM1	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	1.1615101791894256	[21]	[86]	9	hSpCas9	negative selection	10465106
26197995	26198018	1	-	28162770	SKM1	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.6024961305059044	[18]	[50]	6	hSpCas9	negative selection	10465107
26198011	26198034	1	-	28162770	SKM1	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	-0.0009718390673250088	[89]	[158]	0	hSpCas9	negative selection	10465108
26199887	26199910	1	+	28162770	SKM1	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	0.38444917944542084	[38]	[89]	4	hSpCas9	negative selection	10465109
26191396	26191419	1	-	28162770	SKM1	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	-0.9595052217719404	[21]	[19]	-6	hSpCas9	negative selection	10634466
26199946	26199969	1	-	28162770	SKM1	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-0.880895387075574	[24]	[23]	-6	hSpCas9	negative selection	10634467
26197969	26197992	1	+	28162770	SKM1	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	-3.6293566200796095	[6]	[0]	-9	hSpCas9	negative selection	10634468
26190632	26190655	1	+	28162770	SKM1	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.9289169019385176	[41]	[38]	-6	hSpCas9	negative selection	10634469
26190705	26190728	1	+	28162770	SKM1	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.08780049300641635	[32]	[61]	0	hSpCas9	negative selection	10634470
26190722	26190745	1	+	28162770	SKM1	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.9948382948842212	[61]	[54]	-6	hSpCas9	negative selection	10634471
26193830	26193853	1	-	28162770	SKM1	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	1.1615101791894256	[21]	[86]	9	hSpCas9	negative selection	10634472
26197995	26198018	1	-	28162770	SKM1	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.6024961305059044	[18]	[50]	6	hSpCas9	negative selection	10634473
26198011	26198034	1	-	28162770	SKM1	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	-0.0009718390673250088	[89]	[158]	0	hSpCas9	negative selection	10634474
26199887	26199910	1	+	28162770	SKM1	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	0.38444917944542084	[38]	[89]	4	hSpCas9	negative selection	10634475
26191396	26191419	1	-	28162770	PL21	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	1.6350766712058689	[53]	[72]	9	hSpCas9	negative selection	10803832
26199946	26199969	1	-	28162770	PL21	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	1.0905151233148218	[122]	[113]	8	hSpCas9	negative selection	10803833
26197969	26197992	1	+	28162770	PL21	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	-1.3848228862318361	[5]	[0]	-7	hSpCas9	negative selection	10803834
26190632	26190655	1	+	28162770	PL21	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.23726569781797835	[194]	[71]	-2	hSpCas9	negative selection	10803835
26190705	26190728	1	+	28162770	PL21	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.4722857274821755	[203]	[63]	-3	hSpCas9	negative selection	10803836
26190722	26190745	1	+	28162770	PL21	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-1.713604652160261	[210]	[27]	-8	hSpCas9	negative selection	10803837
26193830	26193853	1	-	28162770	PL21	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	-0.06289479134447373	[71]	[29]	0	hSpCas9	negative selection	10803838
26197995	26198018	1	-	28162770	PL21	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.9253912675945388	[47]	[10]	-6	hSpCas9	negative selection	10803839
26198011	26198034	1	-	28162770	PL21	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	-0.7185602834088316	[275]	[72]	-5	hSpCas9	negative selection	10803840
26199887	26199910	1	+	28162770	PL21	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	2.0116945250762095	[97]	[171]	9	hSpCas9	negative selection	10803841
26191396	26191419	1	-	28162770	P31FUJ	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	1.2129975486351523	[57]	[157]	9	hSpCas9	negative selection	10973198
26199946	26199969	1	-	28162770	P31FUJ	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	0.2336206811313764	[130]	[180]	2	hSpCas9	negative selection	10973199
26197969	26197992	1	+	28162770	P31FUJ	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	0.25262462275586284	[9]	[13]	2	hSpCas9	negative selection	10973200
26190632	26190655	1	+	28162770	P31FUJ	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.3615355185365813	[163]	[149]	-3	hSpCas9	negative selection	10973201
26190705	26190728	1	+	28162770	P31FUJ	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.10727132233051978	[175]	[191]	-1	hSpCas9	negative selection	10973202
26190722	26190745	1	+	28162770	P31FUJ	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.6826051218538989	[167]	[122]	-5	hSpCas9	negative selection	10973203
26193830	26193853	1	-	28162770	P31FUJ	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	0.2654486631134465	[79]	[112]	3	hSpCas9	negative selection	10973204
26197995	26198018	1	-	28162770	P31FUJ	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.47565872831054246	[70]	[59]	-4	hSpCas9	negative selection	10973205
26198011	26198034	1	-	28162770	P31FUJ	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	0.1720061625475786	[459]	[608]	1	hSpCas9	negative selection	10973206
26199887	26199910	1	+	28162770	P31FUJ	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	0.25658263632454636	[155]	[218]	2	hSpCas9	negative selection	10973207
26191396	26191419	1	-	28162770	OCIAML5	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	0.7499694432161004	[27]	[84]	6	hSpCas9	negative selection	11142564
26199946	26199969	1	-	28162770	OCIAML5	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	0.09902382865505677	[74]	[144]	0	hSpCas9	negative selection	11142565
26197969	26197992	1	+	28162770	OCIAML5	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	-2.8520665708639967	[3]	[0]	-8	hSpCas9	negative selection	11142566
26190632	26190655	1	+	28162770	OCIAML5	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.8687453120106274	[86]	[85]	-5	hSpCas9	negative selection	11142567
26190705	26190728	1	+	28162770	OCIAML5	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.4977405565988019	[81]	[208]	4	hSpCas9	negative selection	11142568
26190722	26190745	1	+	28162770	OCIAML5	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	0.8297574691097482	[71]	[230]	7	hSpCas9	negative selection	11142569
26193830	26193853	1	-	28162770	OCIAML5	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	0.483536460920442	[41]	[105]	4	hSpCas9	negative selection	11142570
26197995	26198018	1	-	28162770	OCIAML5	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.1415731880589819	[43]	[71]	-1	hSpCas9	negative selection	11142571
26198011	26198034	1	-	28162770	OCIAML5	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	-0.10690964147213977	[280]	[470]	-1	hSpCas9	negative selection	11142572
26199887	26199910	1	+	28162770	OCIAML5	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	-0.13347950601264524	[78]	[129]	-1	hSpCas9	negative selection	11142573
26191396	26191419	1	-	28162770	EOL1	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	0.04002498899047069	[119]	[64]	0	hSpCas9	negative selection	11311930
26199946	26199969	1	-	28162770	EOL1	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-1.1940967249280847	[151]	[34]	-7	hSpCas9	negative selection	11311931
26197969	26197992	1	+	28162770	EOL1	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	1.2326700669328665	[20]	[25]	8	hSpCas9	negative selection	11311932
26190632	26190655	1	+	28162770	EOL1	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.4130335876283134	[277]	[109]	-3	hSpCas9	negative selection	11311933
26190705	26190728	1	+	28162770	EOL1	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.6096744342171228	[305]	[245]	5	hSpCas9	negative selection	11311934
26190722	26190745	1	+	28162770	EOL1	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.5972867505851576	[312]	[108]	-4	hSpCas9	negative selection	11311935
26193830	26193853	1	-	28162770	EOL1	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	0.7977906292845959	[106]	[97]	7	hSpCas9	negative selection	11311936
26197995	26198018	1	-	28162770	EOL1	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.054078577636898384	[66]	[33]	0	hSpCas9	negative selection	11311937
26198011	26198034	1	-	28162770	EOL1	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	0.9779211224463313	[397]	[412]	8	hSpCas9	negative selection	11311938
26199887	26199910	1	+	28162770	EOL1	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	1.3637221767308882	[162]	[220]	9	hSpCas9	negative selection	11311939
26191396	26191419	1	-	28162770	MOLM13	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	1.1288007354990335	[73]	[116]	8	hSpCas9	negative selection	11481296
26199946	26199969	1	-	28162770	MOLM13	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-1.1170731191765777	[107]	[35]	-5	hSpCas9	negative selection	11481297
26197969	26197992	1	+	28162770	MOLM13	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	-3.780038131899007	[18]	[0]	-9	hSpCas9	negative selection	11481298
26190632	26190655	1	+	28162770	MOLM13	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.031681627945932905	[245]	[173]	0	hSpCas9	negative selection	11481299
26190705	26190728	1	+	28162770	MOLM13	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.9634167986837905	[182]	[257]	7	hSpCas9	negative selection	11481300
26190722	26190745	1	+	28162770	MOLM13	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.9504232497671261	[293]	[109]	-5	hSpCas9	negative selection	11481301
26193830	26193853	1	-	28162770	MOLM13	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	0.8664387580348539	[175]	[231]	6	hSpCas9	negative selection	11481302
26197995	26198018	1	-	28162770	MOLM13	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.10987761777237348	[99]	[66]	0	hSpCas9	negative selection	11481303
26198011	26198034	1	-	28162770	MOLM13	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	-0.3206065132617095	[436]	[252]	-2	hSpCas9	negative selection	11481304
26199887	26199910	1	+	28162770	MOLM13	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	0.2350045863904887	[160]	[136]	1	hSpCas9	negative selection	11481305
26191396	26191419	1	-	28162770	HEL	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	1.3227485413544873	[92]	[148]	9	hSpCas9	negative selection	11650662
26199946	26199969	1	-	28162770	HEL	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-2.32304545266173	[124]	[15]	-8	hSpCas9	negative selection	11650663
26197969	26197992	1	+	28162770	HEL	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	4.1021704506376535	[6]	[76]	9	hSpCas9	negative selection	11650664
26190632	26190655	1	+	28162770	HEL	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	0.642738832000357	[238]	[238]	5	hSpCas9	negative selection	11650665
26190705	26190728	1	+	28162770	HEL	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.2901469721411063	[251]	[131]	-2	hSpCas9	negative selection	11650666
26190722	26190745	1	+	28162770	HEL	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	0.08233343552317954	[232]	[157]	0	hSpCas9	negative selection	11650667
26193830	26193853	1	-	28162770	HEL	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	0.14154468897179862	[91]	[64]	1	hSpCas9	negative selection	11650668
26197995	26198018	1	-	28162770	HEL	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.3352348616696441	[64]	[32]	-2	hSpCas9	negative selection	11650669
26198011	26198034	1	-	28162770	HEL	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	0.1995681937374164	[396]	[291]	1	hSpCas9	negative selection	11650670
26199887	26199910	1	+	28162770	HEL	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	-0.8529563306237119	[140]	[49]	-5	hSpCas9	negative selection	11650671
26191396	26191419	1	-	28162770	MV411	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	0.017955704660008065	[67]	[57]	0	hSpCas9	negative selection	11820028
26199946	26199969	1	-	28162770	MV411	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-1.5025841962088773	[110]	[32]	-7	hSpCas9	negative selection	11820029
26197969	26197992	1	+	28162770	MV411	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	0.5953608542030824	[10]	[13]	5	hSpCas9	negative selection	11820030
26190632	26190655	1	+	28162770	MV411	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.054452790868041945	[142]	[115]	0	hSpCas9	negative selection	11820031
26190705	26190728	1	+	28162770	MV411	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.397467490394663	[171]	[109]	-3	hSpCas9	negative selection	11820032
26190722	26190745	1	+	28162770	MV411	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.9749548705536727	[244]	[104]	-6	hSpCas9	negative selection	11820033
26193830	26193853	1	-	28162770	MV411	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	1.4913631336688646	[56]	[134]	9	hSpCas9	negative selection	11820034
26197995	26198018	1	-	28162770	MV411	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.4895280433834308	[54]	[32]	-4	hSpCas9	negative selection	11820035
26198011	26198034	1	-	28162770	MV411	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	0.20393591214618867	[302]	[293]	1	hSpCas9	negative selection	11820036
26199887	26199910	1	+	28162770	MV411	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	0.04211864280526867	[97]	[84]	0	hSpCas9	negative selection	11820037
26191396	26191419	1	-	28162770	MONOMAC1	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	-0.020159084975474473	[45]	[51]	0	hSpCas9	negative selection	11989394
26199946	26199969	1	-	28162770	MONOMAC1	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	0.8854253131324191	[67]	[143]	7	hSpCas9	negative selection	11989395
26197969	26197992	1	+	28162770	MONOMAC1	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	-4.0043917691171576	[13]	[0]	-9	hSpCas9	negative selection	11989396
26190632	26190655	1	+	28162770	MONOMAC1	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.2822042303222309	[156]	[147]	-2	hSpCas9	negative selection	11989397
26190705	26190728	1	+	28162770	MONOMAC1	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	-0.2536203754259212	[129]	[124]	-2	hSpCas9	negative selection	11989398
26190722	26190745	1	+	28162770	MONOMAC1	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.7954198635430316	[161]	[106]	-6	hSpCas9	negative selection	11989399
26193830	26193853	1	-	28162770	MONOMAC1	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	-0.6120743463383975	[51]	[38]	-5	hSpCas9	negative selection	11989400
26197995	26198018	1	-	28162770	MONOMAC1	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.446819342715171	[15]	[24]	4	hSpCas9	negative selection	11989401
26198011	26198034	1	-	28162770	MONOMAC1	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	-0.42081182244612014	[173]	[148]	-4	hSpCas9	negative selection	11989402
26199887	26199910	1	+	28162770	MONOMAC1	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	-0.5096270773675797	[76]	[61]	-4	hSpCas9	negative selection	11989403
26191396	26191419	1	-	28162770	OCIAML2	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	-1.0986610478552035	[16]	[43]	-6	hSpCas9	negative selection	12158760
26199946	26199969	1	-	28162770	OCIAML2	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	-0.44956820971433165	[16]	[68]	-4	hSpCas9	negative selection	12158761
26197969	26197992	1	+	28162770	OCIAML2	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	-0.8856673245210054	[0]	[2]	-6	hSpCas9	negative selection	12158762
26190632	26190655	1	+	28162770	OCIAML2	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	-0.09048711640950322	[33]	[176]	0	hSpCas9	negative selection	12158763
26190705	26190728	1	+	28162770	OCIAML2	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.21828363951790328	[28]	[186]	2	hSpCas9	negative selection	12158764
26190722	26190745	1	+	28162770	OCIAML2	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	-0.8672887952061505	[51]	[157]	-6	hSpCas9	negative selection	12158765
26193830	26193853	1	-	28162770	OCIAML2	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	-0.30916640254804484	[18]	[84]	-3	hSpCas9	negative selection	12158766
26197995	26198018	1	-	28162770	OCIAML2	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	-0.28620525410473396	[10]	[49]	-2	hSpCas9	negative selection	12158767
26198011	26198034	1	-	28162770	OCIAML2	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	0.8562645225385503	[57]	[581]	8	hSpCas9	negative selection	12158768
26199887	26199910	1	+	28162770	OCIAML2	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	-0.13911568152560075	[29]	[150]	-1	hSpCas9	negative selection	12158769
26191396	26191419	1	-	28162770	OCIAML3	viability	GGAGTTGGTACGGAGAGCGATGG	CATSPER4	ENSG00000188782	0.33199177823205983	[19]	[75]	3	hSpCas9	negative selection	12328126
26199946	26199969	1	-	28162770	OCIAML3	viability	GATGCCAATGAAGGCACCGATGG	CATSPER4	ENSG00000188782	0.5129075635923488	[12]	[55]	5	hSpCas9	negative selection	12328127
26197969	26197992	1	+	28162770	OCIAML3	viability	GGTGCATGTGTGCATGGCGGTGG	CATSPER4	ENSG00000188782	1.3445918150116931	[2]	[22]	9	hSpCas9	negative selection	12328128
26190632	26190655	1	+	28162770	OCIAML3	viability	GGGATAATGAAAAGGCCTGGTGG	CATSPER4	ENSG00000188782	0.31957760785836353	[42]	[161]	3	hSpCas9	negative selection	12328129
26190705	26190728	1	+	28162770	OCIAML3	viability	GGACCGTATGGGGTTTGGAGGGG	CATSPER4	ENSG00000188782	0.34683028720769304	[55]	[214]	3	hSpCas9	negative selection	12328130
26190722	26190745	1	+	28162770	OCIAML3	viability	GAGGGGCAGTAGCTGCACTGAGG	CATSPER4	ENSG00000188782	0.15601410666748933	[43]	[147]	1	hSpCas9	negative selection	12328131
26193830	26193853	1	-	28162770	OCIAML3	viability	GAGAACCTCACAAAGAAGGATGG	CATSPER4	ENSG00000188782	-0.6720101523254363	[18]	[35]	-5	hSpCas9	negative selection	12328132
26197995	26198018	1	-	28162770	OCIAML3	viability	GACGCGGATGATCCGGGCGAGGG	CATSPER4	ENSG00000188782	0.5759173611181492	[7]	[35]	5	hSpCas9	negative selection	12328133
26198011	26198034	1	-	28162770	OCIAML3	viability	GCACCGACTGCAGGATGACGCGG	CATSPER4	ENSG00000188782	-0.09924294857458515	[76]	[216]	-1	hSpCas9	negative selection	12328134
26199887	26199910	1	+	28162770	OCIAML3	viability	AGAGAAGAGGGAATATGCAATGG	CATSPER4	ENSG00000188782	0.11540223132148164	[36]	[120]	1	hSpCas9	negative selection	12328135