Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:933
• Symbol:CD22
• Description:CD22 molecule

DataSource: http://genomecrispr.dkfz.de/#!/results/CD22

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
35336047	35336070	19	-	26472758	Jiyoye	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-3.762749619936439	[89]	[4]	-9	hSpCas9	negative selection	27214
35332625	35332648	19	-	26472758	Jiyoye	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-0.14216320948456151	[59]	[40]	-1	hSpCas9	negative selection	27215
35336129	35336152	19	+	26472758	Jiyoye	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	1.13111429537584	[88]	[146]	7	hSpCas9	negative selection	27216
35336307	35336330	19	-	26472758	Jiyoye	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	0.04189091742412909	[379]	[294]	0	hSpCas9	negative selection	27217
35341024	35341047	19	-	26472758	Jiyoye	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.6136262589732997	[38]	[44]	4	hSpCas9	negative selection	27218
35341112	35341135	19	-	26472758	Jiyoye	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	-0.9705259664999978	[355]	[136]	-6	hSpCas9	negative selection	27219
35341789	35341812	19	-	26472758	Jiyoye	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	3.214530303563477	[0]	[6]	9	hSpCas9	negative selection	27220
35341859	35341882	19	+	26472758	Jiyoye	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	-1.0465425859370303	[125]	[45]	-6	hSpCas9	negative selection	27221
35344904	35344927	19	+	26472758	Jiyoye	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	0.8557654404957438	[84]	[115]	6	hSpCas9	negative selection	27222
35345056	35345079	19	+	26472758	Jiyoye	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-1.0318307655993013	[262]	[96]	-6	hSpCas9	negative selection	27223
35336047	35336070	19	-	26472758	KBM7	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-0.6108996585032187	[246,80]	[92,7]	-5	hSpCas9	negative selection	218332
35332625	35332648	19	-	26472758	KBM7	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-1.248634453191263	[257,181]	[33,50]	-7	hSpCas9	negative selection	218333
35336129	35336152	19	+	26472758	KBM7	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-0.16601572419081062	[690,623]	[266,282]	-2	hSpCas9	negative selection	218334
35336307	35336330	19	-	26472758	KBM7	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.002151217503114422	[1487,1131]	[694,532]	0	hSpCas9	negative selection	218335
35341024	35341047	19	-	26472758	KBM7	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.3163359345100335	[279,213]	[136,148]	3	hSpCas9	negative selection	218336
35341112	35341135	19	-	26472758	KBM7	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.5683486469176996	[1018,705]	[694,501]	6	hSpCas9	negative selection	218337
35341789	35341812	19	-	26472758	KBM7	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-0.7044814219959226	[83,94]	[23,27]	-5	hSpCas9	negative selection	218338
35341859	35341882	19	+	26472758	KBM7	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	-0.19300476161588187	[144,246]	[117,51]	-2	hSpCas9	negative selection	218339
35344904	35344927	19	+	26472758	KBM7	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	0.9062072451602833	[346,282]	[246,301]	8	hSpCas9	negative selection	218340
35345056	35345079	19	+	26472758	KBM7	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.15804366799275127	[548,586]	[149,322]	-1	hSpCas9	negative selection	218341
35336047	35336070	19	-	26472758	Raji	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-4.102069830255351	[73]	[0]	-9	hSpCas9	negative selection	409450
35332625	35332648	19	-	26472758	Raji	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	0.6870517364252428	[90]	[33]	6	hSpCas9	negative selection	409451
35336129	35336152	19	+	26472758	Raji	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.6579053907657262	[324]	[118]	6	hSpCas9	negative selection	409452
35336307	35336330	19	-	26472758	Raji	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	0.6887794210745632	[539]	[201]	6	hSpCas9	negative selection	409453
35341024	35341047	19	-	26472758	Raji	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.32977595671004756	[71]	[20]	3	hSpCas9	negative selection	409454
35341112	35341135	19	-	26472758	Raji	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.3395569775026327	[377]	[110]	3	hSpCas9	negative selection	409455
35341789	35341812	19	-	26472758	Raji	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-2.750597459753973	[28]	[0]	-9	hSpCas9	negative selection	409456
35341859	35341882	19	+	26472758	Raji	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	0.27088226765647894	[149]	[41]	2	hSpCas9	negative selection	409457
35344904	35344927	19	+	26472758	Raji	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	0.012865936589309596	[204]	[47]	0	hSpCas9	negative selection	409458
35345056	35345079	19	+	26472758	Raji	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.3325665338707319	[330]	[60]	-3	hSpCas9	negative selection	409459
35336047	35336070	19	-	26472758	K562	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-6.483501726896751	[105]	[0]	-9	hSpCas9	negative selection	600568
35332625	35332648	19	-	26472758	K562	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-2.755581272333553	[191]	[23]	-8	hSpCas9	negative selection	600569
35336129	35336152	19	+	26472758	K562	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-0.36239449427636916	[631]	[414]	-2	hSpCas9	negative selection	600570
35336307	35336330	19	-	26472758	K562	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.20867211738410463	[1049]	[766]	-1	hSpCas9	negative selection	600571
35341024	35341047	19	-	26472758	K562	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.6573937604883981	[174]	[232]	5	hSpCas9	negative selection	600572
35341112	35341135	19	-	26472758	K562	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.4263021934168141	[840]	[953]	3	hSpCas9	negative selection	600573
35341789	35341812	19	-	26472758	K562	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-4.8430441135838915	[33]	[0]	-9	hSpCas9	negative selection	600574
35341859	35341882	19	+	26472758	K562	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	-0.25034596408313103	[216]	[153]	-2	hSpCas9	negative selection	600575
35344904	35344927	19	+	26472758	K562	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	-0.4750858964335369	[437]	[265]	-3	hSpCas9	negative selection	600576
35345056	35345079	19	+	26472758	K562	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.5503141100220514	[568]	[327]	-3	hSpCas9	negative selection	600577
35332070	35332093	19	-	26627737	DLD1	viability	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.4154039543003507	[1032]	[380,608,325]	4	hSpCas9	negative selection	804149
35332834	35332857	19	-	26627737	DLD1	viability	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	0.6524889487628075	[770]	[337,488,322]	6	hSpCas9	negative selection	804150
35336102	35336125	19	-	26627737	DLD1	viability	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	1.3411702873947409	[228]	[277,198,82]	9	hSpCas9	negative selection	804151
35337966	35337989	19	+	26627737	DLD1	viability	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	-0.8418810255859921	[273]	[79,43,22]	-7	hSpCas9	negative selection	804152
35338382	35338405	19	+	26627737	DLD1	viability	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.29008459375844664	[345]	[162,45,176]	3	hSpCas9	negative selection	804153
35341117	35341140	19	-	26627737	DLD1	viability	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.8894692655175654	[419]	[132,324,270]	8	hSpCas9	negative selection	804154
35332070	35332093	19	-	26627737	GBM cells	viability after 5 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.25073873153036563	[476]	[211,217]	-4	hSpCas9	negative selection	886464
35332834	35332857	19	-	26627737	GBM cells	viability after 5 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.2799342055782429	[445]	[182,210]	-4	hSpCas9	negative selection	886465
35336102	35336125	19	-	26627737	GBM cells	viability after 5 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.44106329206786854	[56]	[30,51]	6	hSpCas9	negative selection	886466
35337966	35337989	19	+	26627737	GBM cells	viability after 5 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	1.2800040422411914	[42]	[59,51]	9	hSpCas9	negative selection	886467
35338382	35338405	19	+	26627737	GBM cells	viability after 5 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.09893848319367901	[194]	[136,86]	1	hSpCas9	negative selection	886468
35341117	35341140	19	-	26627737	GBM cells	viability after 5 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.3977197318571271	[183]	[107,151]	6	hSpCas9	negative selection	886469
35332070	35332093	19	-	26627737	GBM cells	viability after 13 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.04812854561425073	[476]	[271,263]	0	hSpCas9	negative selection	968779
35332834	35332857	19	-	26627737	GBM cells	viability after 13 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.8397042104009607	[445]	[148,123]	-7	hSpCas9	negative selection	968780
35336102	35336125	19	-	26627737	GBM cells	viability after 13 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	-0.4779168976241923	[56]	[19,23]	-5	hSpCas9	negative selection	968781
35337966	35337989	19	+	26627737	GBM cells	viability after 13 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	1.7503239770212247	[42]	[99,60]	9	hSpCas9	negative selection	968782
35338382	35338405	19	+	26627737	GBM cells	viability after 13 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.1732408263523607	[194]	[174,73]	2	hSpCas9	negative selection	968783
35341117	35341140	19	-	26627737	GBM cells	viability after 13 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.6882715645194225	[183]	[172,150]	8	hSpCas9	negative selection	968784
35332070	35332093	19	-	26627737	GBM cells	viability after 21 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.686695278275236	[476]	[160,160]	-6	hSpCas9	negative selection	1051094
35332834	35332857	19	-	26627737	GBM cells	viability after 21 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.8144671964727211	[445]	[142,132]	-6	hSpCas9	negative selection	1051095
35336102	35336125	19	-	26627737	GBM cells	viability after 21 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	-0.09026042893351693	[56]	[26,30]	-1	hSpCas9	negative selection	1051096
35337966	35337989	19	+	26627737	GBM cells	viability after 21 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	1.0748807304692019	[42]	[55,42]	9	hSpCas9	negative selection	1051097
35338382	35338405	19	+	26627737	GBM cells	viability after 21 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-0.960973051899649	[194]	[67,41]	-7	hSpCas9	negative selection	1051098
35341117	35341140	19	-	26627737	GBM cells	viability after 21 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.2070318429609807	[183]	[117,112]	2	hSpCas9	negative selection	1051099
35332070	35332093	19	-	26627737	RPE1	viability after 9 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.755405548308714	[2377]	[540,311]	-5	hSpCas9	negative selection	1133409
35332834	35332857	19	-	26627737	RPE1	viability after 9 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.3246674161389013	[1069]	[163,400]	-2	hSpCas9	negative selection	1133410
35336102	35336125	19	-	26627737	RPE1	viability after 9 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.9620866751960713	[686]	[294,578]	6	hSpCas9	negative selection	1133411
35337966	35337989	19	+	26627737	RPE1	viability after 9 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	-1.750891318499562	[555]	[35,71]	-8	hSpCas9	negative selection	1133412
35338382	35338405	19	+	26627737	RPE1	viability after 9 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-1.635193727092544	[1039]	[75,141]	-8	hSpCas9	negative selection	1133413
35341117	35341140	19	-	26627737	RPE1	viability after 9 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.6836815530104091	[683]	[291,410]	4	hSpCas9	negative selection	1133414
35332070	35332093	19	-	26627737	RPE1	viability after 12 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.8233382143914404	[2377]	[532,178]	-5	hSpCas9	negative selection	1215724
35332834	35332857	19	-	26627737	RPE1	viability after 12 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.2574762845617341	[1069]	[86,402]	-2	hSpCas9	negative selection	1215725
35336102	35336125	19	-	26627737	RPE1	viability after 12 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.6502898531672066	[686]	[227,354]	4	hSpCas9	negative selection	1215726
35337966	35337989	19	+	26627737	RPE1	viability after 12 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	-1.0794828930189664	[555]	[42,99]	-6	hSpCas9	negative selection	1215727
35338382	35338405	19	+	26627737	RPE1	viability after 12 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-1.1447298914016297	[1039]	[104,148]	-7	hSpCas9	negative selection	1215728
35341117	35341140	19	-	26627737	RPE1	viability after 12 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.8710669487293377	[683]	[339,331]	5	hSpCas9	negative selection	1215729
35332070	35332093	19	-	26627737	RPE1	viability after 15 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.6783500635509151	[2377]	[653,194]	-4	hSpCas9	negative selection	1298039
35332834	35332857	19	-	26627737	RPE1	viability after 15 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.33385828654381855	[1069]	[62,410]	-2	hSpCas9	negative selection	1298040
35336102	35336125	19	-	26627737	RPE1	viability after 15 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.641381228402665	[686]	[351,255]	4	hSpCas9	negative selection	1298041
35337966	35337989	19	+	26627737	RPE1	viability after 15 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	-1.0378856232775369	[555]	[98,54]	-6	hSpCas9	negative selection	1298042
35338382	35338405	19	+	26627737	RPE1	viability after 15 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-0.8540149595252493	[1039]	[119,203]	-5	hSpCas9	negative selection	1298043
35341117	35341140	19	-	26627737	RPE1	viability after 15 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.7634173704104692	[683]	[246,406]	5	hSpCas9	negative selection	1298044
35332070	35332093	19	-	26627737	RPE1	viability after 18 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-1.542610441344166	[2377]	[286,148]	-7	hSpCas9	negative selection	1380354
35332834	35332857	19	-	26627737	RPE1	viability after 18 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.004039249603121853	[1069]	[169,413]	0	hSpCas9	negative selection	1380355
35336102	35336125	19	-	26627737	RPE1	viability after 18 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.7412293105961159	[686]	[321,296]	4	hSpCas9	negative selection	1380356
35337966	35337989	19	+	26627737	RPE1	viability after 18 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	-0.9556650060718495	[555]	[87,65]	-5	hSpCas9	negative selection	1380357
35338382	35338405	19	+	26627737	RPE1	viability after 18 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-1.2295744465726854	[1039]	[95,144]	-6	hSpCas9	negative selection	1380358
35341117	35341140	19	-	26627737	RPE1	viability after 18 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	1.2287119224367324	[683]	[420,444]	7	hSpCas9	negative selection	1380359
35332070	35332093	19	-	26627737	HeLa	viability after 8 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.019560507981503994	[855]	[396,451,293]	0	hSpCas9	negative selection	1462669
35332834	35332857	19	-	26627737	HeLa	viability after 8 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	0.08203862728344036	[594]	[284,345,198]	0	hSpCas9	negative selection	1462670
35336102	35336125	19	-	26627737	HeLa	viability after 8 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.15307439098513942	[513]	[241,318,187]	1	hSpCas9	negative selection	1462671
35337966	35337989	19	+	26627737	HeLa	viability after 8 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	1.2130210280407858	[46]	[79,15,52]	8	hSpCas9	negative selection	1462672
35338382	35338405	19	+	26627737	HeLa	viability after 8 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.7438443356001608	[211]	[248,165,74]	6	hSpCas9	negative selection	1462673
35341117	35341140	19	-	26627737	HeLa	viability after 8 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	1.1469960808436657	[116]	[263,75,36]	8	hSpCas9	negative selection	1462674
35332070	35332093	19	-	26627737	HeLa	viability after 12 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.16177574637302772	[855]	[194,515,212]	-1	hSpCas9	negative selection	1544984
35332834	35332857	19	-	26627737	HeLa	viability after 12 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	0.5945035028886005	[594]	[482,343,292]	5	hSpCas9	negative selection	1544985
35336102	35336125	19	-	26627737	HeLa	viability after 12 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.1676210238423349	[513]	[327,175,220]	1	hSpCas9	negative selection	1544986
35337966	35337989	19	+	26627737	HeLa	viability after 12 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	1.9484155036474171	[46]	[13,94,111]	9	hSpCas9	negative selection	1544987
35338382	35338405	19	+	26627737	HeLa	viability after 12 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-0.18418709992552573	[211]	[79,14,142]	-2	hSpCas9	negative selection	1544988
35341117	35341140	19	-	26627737	HeLa	viability after 12 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	2.0475968483616187	[116]	[154,278,155]	9	hSpCas9	negative selection	1544989
35332070	35332093	19	-	26627737	HeLa	viability after 15 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.4566114985960712	[855]	[166,316,280]	-4	hSpCas9	negative selection	1627299
35332834	35332857	19	-	26627737	HeLa	viability after 15 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	0.22364081507475886	[594]	[185,341,324]	2	hSpCas9	negative selection	1627300
35336102	35336125	19	-	26627737	HeLa	viability after 15 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	-0.2121178558875966	[513]	[135,255,147]	-2	hSpCas9	negative selection	1627301
35337966	35337989	19	+	26627737	HeLa	viability after 15 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	-2.2801795792688706	[46]	[1,3,5]	-9	hSpCas9	negative selection	1627302
35338382	35338405	19	+	26627737	HeLa	viability after 15 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.22307077971686717	[211]	[131,102,63]	2	hSpCas9	negative selection	1627303
35341117	35341140	19	-	26627737	HeLa	viability after 15 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	1.7323557054808199	[116]	[83,157,239]	9	hSpCas9	negative selection	1627304
35332070	35332093	19	-	26627737	HeLa	viability after 18 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.3988956766636299	[855]	[130,263,280]	-3	hSpCas9	negative selection	1709614
35332834	35332857	19	-	26627737	HeLa	viability after 18 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	0.22796690579467938	[594]	[124,284,324]	2	hSpCas9	negative selection	1709615
35336102	35336125	19	-	26627737	HeLa	viability after 18 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	-0.22048205714929284	[513]	[89,210,147]	-2	hSpCas9	negative selection	1709616
35337966	35337989	19	+	26627737	HeLa	viability after 18 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	-2.569338464462035	[46]	[0,1,5]	-9	hSpCas9	negative selection	1709617
35338382	35338405	19	+	26627737	HeLa	viability after 18 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.25944302885126	[211]	[92,85,63]	2	hSpCas9	negative selection	1709618
35341117	35341140	19	-	26627737	HeLa	viability after 18 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	1.7600945954721712	[116]	[62,129,239]	9	hSpCas9	negative selection	1709619
35332070	35332093	19	-	26627737	HCT116	viability after 6 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.5564170829895008	[1549]	[824,100]	3	hSpCas9	negative selection	1791929
35332834	35332857	19	-	26627737	HCT116	viability after 6 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	1.1002267775388568	[647]	[365,136]	6	hSpCas9	negative selection	1791930
35336102	35336125	19	-	26627737	HCT116	viability after 6 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.012898550655503271	[509]	[174,28]	0	hSpCas9	negative selection	1791931
35337966	35337989	19	+	26627737	HCT116	viability after 6 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	0.5215169495535541	[25]	[1,7]	3	hSpCas9	negative selection	1791932
35338382	35338405	19	+	26627737	HCT116	viability after 6 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.4873198795884133	[439]	[163,59]	2	hSpCas9	negative selection	1791933
35341117	35341140	19	-	26627737	HCT116	viability after 6 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	1.4045180831539499	[394]	[233,125]	7	hSpCas9	negative selection	1791934
35332070	35332093	19	-	26627737	HCT116	viability after 8 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.36186302654469304	[765]	[290,308,383]	-4	hSpCas9	negative selection	1874244
35332834	35332857	19	-	26627737	HCT116	viability after 8 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	0.38970667487475263	[329]	[339,260,116]	4	hSpCas9	negative selection	1874245
35336102	35336125	19	-	26627737	HCT116	viability after 8 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.6501438196296536	[238]	[130,225,260]	6	hSpCas9	negative selection	1874246
35337966	35337989	19	+	26627737	HCT116	viability after 8 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	1.5728552162208331	[33]	[51,47,66]	9	hSpCas9	negative selection	1874247
35338382	35338405	19	+	26627737	HCT116	viability after 8 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.6947426769898754	[158]	[168,121,134]	6	hSpCas9	negative selection	1874248
35341117	35341140	19	-	26627737	HCT116	viability after 8 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.8400230689238768	[206]	[183,208,218]	7	hSpCas9	negative selection	1874249
35332070	35332093	19	-	26627737	HCT116	viability after 9 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-1.2405153357186003	[1549]	[268,100]	-7	hSpCas9	negative selection	1956559
35332834	35332857	19	-	26627737	HCT116	viability after 9 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	1.3477396356925326	[647]	[555,348]	8	hSpCas9	negative selection	1956560
35336102	35336125	19	-	26627737	HCT116	viability after 9 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.37279778588748014	[509]	[72,257]	2	hSpCas9	negative selection	1956561
35337966	35337989	19	+	26627737	HCT116	viability after 9 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	3.1725162655726633	[25]	[13,100]	9	hSpCas9	negative selection	1956562
35338382	35338405	19	+	26627737	HCT116	viability after 9 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.1180345034054438	[439]	[198,70]	0	hSpCas9	negative selection	1956563
35341117	35341140	19	-	26627737	HCT116	viability after 9 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	1.4825297521881662	[394]	[220,352]	8	hSpCas9	negative selection	1956564
35332070	35332093	19	-	26627737	HCT116	viability after 12 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.6989498301646236	[765]	[264,311,166]	-6	hSpCas9	negative selection	2038874
35332834	35332857	19	-	26627737	HCT116	viability after 12 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	0.21115095410417417	[329]	[233,144,218]	2	hSpCas9	negative selection	2038875
35336102	35336125	19	-	26627737	HCT116	viability after 12 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.7114471511009068	[238]	[220,178,214]	6	hSpCas9	negative selection	2038876
35337966	35337989	19	+	26627737	HCT116	viability after 12 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	0.6764654302760791	[33]	[32,16,34]	6	hSpCas9	negative selection	2038877
35338382	35338405	19	+	26627737	HCT116	viability after 12 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.23288227974858378	[158]	[120,73,96]	2	hSpCas9	negative selection	2038878
35341117	35341140	19	-	26627737	HCT116	viability after 12 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.6941061408113917	[206]	[134,109,284]	6	hSpCas9	negative selection	2038879
35332070	35332093	19	-	26627737	HCT116	viability after 15 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.058365189731575784	[765]	[324,462,466]	0	hSpCas9	negative selection	2121189
35332834	35332857	19	-	26627737	HCT116	viability after 15 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.3587654239921131	[329]	[175,138,131]	-4	hSpCas9	negative selection	2121190
35336102	35336125	19	-	26627737	HCT116	viability after 15 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.9506319057665755	[238]	[402,177,231]	7	hSpCas9	negative selection	2121191
35337966	35337989	19	+	26627737	HCT116	viability after 15 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	1.908067660672029	[33]	[21,67,122]	9	hSpCas9	negative selection	2121192
35338382	35338405	19	+	26627737	HCT116	viability after 15 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-0.5273325751536825	[158]	[82,90,18]	-5	hSpCas9	negative selection	2121193
35341117	35341140	19	-	26627737	HCT116	viability after 15 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.6520293767000725	[206]	[256,128,182]	6	hSpCas9	negative selection	2121194
35332070	35332093	19	-	26627737	HCT116	viability after 18 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.46296514924186216	[765]	[330,225,250]	-4	hSpCas9	negative selection	2203504
35332834	35332857	19	-	26627737	HCT116	viability after 18 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.08157616431416403	[329]	[190,153,104]	0	hSpCas9	negative selection	2203505
35336102	35336125	19	-	26627737	HCT116	viability after 18 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.92782772652459	[238]	[183,126,360]	7	hSpCas9	negative selection	2203506
35337966	35337989	19	+	26627737	HCT116	viability after 18 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	2.4592951721207514	[33]	[70,99,99]	9	hSpCas9	negative selection	2203507
35338382	35338405	19	+	26627737	HCT116	viability after 18 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-0.7493451617119572	[158]	[20,65,48]	-6	hSpCas9	negative selection	2203508
35341117	35341140	19	-	26627737	HCT116	viability after 18 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.8006286813559645	[206]	[182,195,140]	6	hSpCas9	negative selection	2203509
35329022	35329045	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCGGGCTCGGAGTCAGATTGG	CD22	ENSG00000012124	1.8081227730519434	[350,201]	[345,67]	6	dCas9-VP64	positive selection	2408226
35328979	35329002	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTTCTTCCTTTCCGTGTATGG	CD22	ENSG00000012124	2.491225499142968	[426,485]	[80,1089]	8	dCas9-VP64	positive selection	2408227
35329048	35329071	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGGGGAAAAGAGACGATTGAGG	CD22	ENSG00000012124	2.3120875430329253	[95,114]	[130,98]	7	dCas9-VP64	positive selection	2408228
35330095	35330118	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGGGGATCACCTGAGGTCAGG	CD22	ENSG00000012124	2.0756360988061657	[163,24]	[148,19]	7	dCas9-VP64	positive selection	2422638
35325826	35325849	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTTTGACTATGATGTGTCTTGG	CD22	ENSG00000012124	-0.9776001312623527	[52,165]	[12,10]	-6	dCas9-VP64	positive selection	2458246
35329022	35329045	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCGGGCTCGGAGTCAGATTGG	CD22	ENSG00000012124	0.4597784691781576	[148,95]	[46,62]	3	dCas9-VP64	positive selection	2503481
35328979	35329002	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTTCTTCCTTTCCGTGTATGG	CD22	ENSG00000012124	0.04606273253367088	[126,529]	[77,137]	0	dCas9-VP64	positive selection	2503482
35329048	35329071	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGGGGAAAAGAGACGATTGAGG	CD22	ENSG00000012124	1.4026637065342886	[293,207]	[126,301]	7	dCas9-VP64	positive selection	2503483
35330095	35330118	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGGGGATCACCTGAGGTCAGG	CD22	ENSG00000012124	1.4214284980238518	[47,35]	[16,54]	7	dCas9-VP64	positive selection	2517893
35325826	35325849	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTTTGACTATGATGTGTCTTGG	CD22	ENSG00000012124	-0.07117846671772021	[122,455]	[50,124]	0	dCas9-VP64	positive selection	2553501
35332715	35332738	19	-	27260157	DLD1	viability	TCTTGTCCCATCAAACTTCGAGG	CD22	ENSG00000012124	0.0771340276501964	[]	[]	3	hSpCas9	negative selection	2573881
35337918	35337941	19	+	27260157	DLD1	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.346970241797968	[]	[]	4	hSpCas9	negative selection	2574796
35332595	35332618	19	+	27260157	DLD1	viability	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	1.15096294831803	[]	[]	9	hSpCas9	negative selection	2576598
35332834	35332857	19	+	27260157	DLD1	viability	CCGGTGCACCTCAATGACAGTGG	CD22	ENSG00000012124	-0.40344174422438	[]	[]	-3	hSpCas9	negative selection	2584944
35336243	35336266	19	-	27260157	DLD1	viability	CCCATGGTGACTCCACTGTGGGG	CD22	ENSG00000012124	-0.124678630430599	[]	[]	-1	hSpCas9	negative selection	2586116
35336307	35336330	19	-	27260157	DLD1	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	0.275862616423642	[]	[]	4	hSpCas9	negative selection	2586743
35336129	35336152	19	+	27260157	DLD1	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-0.0202637230807618	[]	[]	0	hSpCas9	negative selection	2607342
35336259	35336282	19	-	27260157	DLD1	viability	GGCAGGTCACAATCTTCCCATGG	CD22	ENSG00000012124	0.56433740676197	[]	[]	8	hSpCas9	negative selection	2609005
35336134	35336157	19	-	27260157	DLD1	viability	AGGAGCCACTGCAATTGGATCGG	CD22	ENSG00000012124	0.926143372577936	[]	[]	9	hSpCas9	negative selection	2610507
35337921	35337944	19	-	27260157	DLD1	viability	GGTCCTTGGTCACTTCGCGCAGG	CD22	ENSG00000012124	-3.21717531125618	[]	[]	-9	hSpCas9	negative selection	2612324
35336120	35336143	19	-	27260157	DLD1	viability	TTGGATCGGATACCCATAGCAGG	CD22	ENSG00000012124	0.272946002086347	[]	[]	4	hSpCas9	negative selection	2614455
35332830	35332853	19	-	27260157	DLD1	viability	TGTCATTGAGGTGCACCGGGTGG	CD22	ENSG00000012124	-0.17315827915732	[]	[]	-1	hSpCas9	negative selection	2616058
35337858	35337881	19	+	27260157	DLD1	viability	CACGACGGTATCCTGGCTCAAGG	CD22	ENSG00000012124	-0.135249934224619	[]	[]	-1	hSpCas9	negative selection	2618792
35337843	35337866	19	+	27260157	DLD1	viability	CAGCAACCCGGAGTACACGACGG	CD22	ENSG00000012124	-0.131619489486624	[]	[]	-1	hSpCas9	negative selection	2622601
35336102	35336125	19	-	27260157	DLD1	viability	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.507240183898044	[]	[]	8	hSpCas9	negative selection	2623865
35332844	35332867	19	+	27260157	DLD1	viability	TCAATGACAGTGGTCAGCTGGGG	CD22	ENSG00000012124	-1.08591507498391	[]	[]	-7	hSpCas9	negative selection	2645637
35336222	35336245	19	-	27260157	DLD1	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.54732666649917	[]	[]	8	hSpCas9	negative selection	2646599
35332032	35332055	19	+	27260157	DLD1	viability	CACGACACCATGCATCTCCTCGG	CD22	ENSG00000012124	-0.0820592346668922	[]	[]	0	hSpCas9	negative selection	2648134
35332638	35332661	19	-	27260157	DLD1	viability	CTAGGGCTCTGTAGGTGCAGGGG	CD22	ENSG00000012124	-0.26195625026197	[]	[]	-2	hSpCas9	negative selection	2649405
35337849	35337872	19	-	27260157	DLD1	viability	AGGATACCGTCGTGTACTCCGGG	CD22	ENSG00000012124	0.109675543808695	[]	[]	3	hSpCas9	negative selection	2649664
35332715	35332738	19	-	27260157	HT1080	viability	TCTTGTCCCATCAAACTTCGAGG	CD22	ENSG00000012124	0.245095912584169	[]	[]	2	hSpCas9	negative selection	2650011
35337918	35337941	19	+	27260157	HT1080	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.537908178401077	[]	[]	5	hSpCas9	negative selection	2650926
35332595	35332618	19	+	27260157	HT1080	viability	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	0.837857354182057	[]	[]	7	hSpCas9	negative selection	2652728
35332834	35332857	19	+	27260157	HT1080	viability	CCGGTGCACCTCAATGACAGTGG	CD22	ENSG00000012124	-1.82381068796421	[]	[]	-9	hSpCas9	negative selection	2661074
35336243	35336266	19	-	27260157	HT1080	viability	CCCATGGTGACTCCACTGTGGGG	CD22	ENSG00000012124	-0.222310783059408	[]	[]	0	hSpCas9	negative selection	2662246
35336307	35336330	19	-	27260157	HT1080	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	0.356087666548936	[]	[]	3	hSpCas9	negative selection	2662873
35336129	35336152	19	+	27260157	HT1080	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-0.045144414730239	[]	[]	0	hSpCas9	negative selection	2683472
35336259	35336282	19	-	27260157	HT1080	viability	GGCAGGTCACAATCTTCCCATGG	CD22	ENSG00000012124	-0.932023357324485	[]	[]	-8	hSpCas9	negative selection	2685135
35336134	35336157	19	-	27260157	HT1080	viability	AGGAGCCACTGCAATTGGATCGG	CD22	ENSG00000012124	1.48408795929203	[]	[]	9	hSpCas9	negative selection	2686637
35337921	35337944	19	-	27260157	HT1080	viability	GGTCCTTGGTCACTTCGCGCAGG	CD22	ENSG00000012124	-2.31605273586711	[]	[]	-9	hSpCas9	negative selection	2688454
35336120	35336143	19	-	27260157	HT1080	viability	TTGGATCGGATACCCATAGCAGG	CD22	ENSG00000012124	0.533044923450113	[]	[]	5	hSpCas9	negative selection	2690585
35332830	35332853	19	-	27260157	HT1080	viability	TGTCATTGAGGTGCACCGGGTGG	CD22	ENSG00000012124	0.313530888258894	[]	[]	3	hSpCas9	negative selection	2692188
35337858	35337881	19	+	27260157	HT1080	viability	CACGACGGTATCCTGGCTCAAGG	CD22	ENSG00000012124	-0.0557204599779559	[]	[]	0	hSpCas9	negative selection	2694922
35337843	35337866	19	+	27260157	HT1080	viability	CAGCAACCCGGAGTACACGACGG	CD22	ENSG00000012124	0.445893929188056	[]	[]	4	hSpCas9	negative selection	2698731
35336102	35336125	19	-	27260157	HT1080	viability	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.790228349656996	[]	[]	7	hSpCas9	negative selection	2699995
35332844	35332867	19	+	27260157	HT1080	viability	TCAATGACAGTGGTCAGCTGGGG	CD22	ENSG00000012124	-0.10114763121891	[]	[]	0	hSpCas9	negative selection	2721767
35336222	35336245	19	-	27260157	HT1080	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.436859529292435	[]	[]	-7	hSpCas9	negative selection	2722729
35332032	35332055	19	+	27260157	HT1080	viability	CACGACACCATGCATCTCCTCGG	CD22	ENSG00000012124	0.100440141143848	[]	[]	1	hSpCas9	negative selection	2724264
35332638	35332661	19	-	27260157	HT1080	viability	CTAGGGCTCTGTAGGTGCAGGGG	CD22	ENSG00000012124	0.295790787419122	[]	[]	2	hSpCas9	negative selection	2725535
35337849	35337872	19	-	27260157	HT1080	viability	AGGATACCGTCGTGTACTCCGGG	CD22	ENSG00000012124	0.689738103046046	[]	[]	6	hSpCas9	negative selection	2725794
35332715	35332738	19	-	27260157	MKN45	viability	TCTTGTCCCATCAAACTTCGAGG	CD22	ENSG00000012124	0.0921196121035113	[]	[]	0	hSpCas9	negative selection	2726141
35337918	35337941	19	+	27260157	MKN45	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.211620048215983	[]	[]	-1	hSpCas9	negative selection	2727056
35332595	35332618	19	+	27260157	MKN45	viability	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	0.315829381340628	[]	[]	5	hSpCas9	negative selection	2728858
35332834	35332857	19	+	27260157	MKN45	viability	CCGGTGCACCTCAATGACAGTGG	CD22	ENSG00000012124	-1.23940768512177	[]	[]	-8	hSpCas9	negative selection	2737204
35336243	35336266	19	-	27260157	MKN45	viability	CCCATGGTGACTCCACTGTGGGG	CD22	ENSG00000012124	-1.16714162669479	[]	[]	-8	hSpCas9	negative selection	2738376
35336307	35336330	19	-	27260157	MKN45	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.877155554024344	[]	[]	-7	hSpCas9	negative selection	2739003
35336129	35336152	19	+	27260157	MKN45	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-1.34129703348539	[]	[]	-8	hSpCas9	negative selection	2759602
35336259	35336282	19	-	27260157	MKN45	viability	GGCAGGTCACAATCTTCCCATGG	CD22	ENSG00000012124	-1.71773907874886	[]	[]	-9	hSpCas9	negative selection	2761265
35336134	35336157	19	-	27260157	MKN45	viability	AGGAGCCACTGCAATTGGATCGG	CD22	ENSG00000012124	0.255460513854164	[]	[]	5	hSpCas9	negative selection	2762767
35337921	35337944	19	-	27260157	MKN45	viability	GGTCCTTGGTCACTTCGCGCAGG	CD22	ENSG00000012124	-2.11074673596203	[]	[]	-9	hSpCas9	negative selection	2764584
35336120	35336143	19	-	27260157	MKN45	viability	TTGGATCGGATACCCATAGCAGG	CD22	ENSG00000012124	0.442501468425212	[]	[]	6	hSpCas9	negative selection	2766715
35332830	35332853	19	-	27260157	MKN45	viability	TGTCATTGAGGTGCACCGGGTGG	CD22	ENSG00000012124	-0.829167815864078	[]	[]	-7	hSpCas9	negative selection	2768318
35337858	35337881	19	+	27260157	MKN45	viability	CACGACGGTATCCTGGCTCAAGG	CD22	ENSG00000012124	-1.04636138434386	[]	[]	-8	hSpCas9	negative selection	2771052
35337843	35337866	19	+	27260157	MKN45	viability	CAGCAACCCGGAGTACACGACGG	CD22	ENSG00000012124	-0.479721981386537	[]	[]	-6	hSpCas9	negative selection	2774861
35336102	35336125	19	-	27260157	MKN45	viability	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.340133998750818	[]	[]	6	hSpCas9	negative selection	2776125
35332844	35332867	19	+	27260157	MKN45	viability	TCAATGACAGTGGTCAGCTGGGG	CD22	ENSG00000012124	-0.608584816583368	[]	[]	-6	hSpCas9	negative selection	2797897
35336222	35336245	19	-	27260157	MKN45	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.247505497292425	[]	[]	5	hSpCas9	negative selection	2798859
35332032	35332055	19	+	27260157	MKN45	viability	CACGACACCATGCATCTCCTCGG	CD22	ENSG00000012124	-0.116195303197804	[]	[]	0	hSpCas9	negative selection	2800394
35332638	35332661	19	-	27260157	MKN45	viability	CTAGGGCTCTGTAGGTGCAGGGG	CD22	ENSG00000012124	-0.25766208196555	[]	[]	-1	hSpCas9	negative selection	2801665
35337849	35337872	19	-	27260157	MKN45	viability	AGGATACCGTCGTGTACTCCGGG	CD22	ENSG00000012124	-0.834564474646414	[]	[]	-7	hSpCas9	negative selection	2801924
35332715	35332738	19	-	27260157	RKO	viability	TCTTGTCCCATCAAACTTCGAGG	CD22	ENSG00000012124	0.0669045592472363	[]	[]	0	hSpCas9	negative selection	2802271
35337918	35337941	19	+	27260157	RKO	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.738314483846586	[]	[]	8	hSpCas9	negative selection	2803186
35332595	35332618	19	+	27260157	RKO	viability	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	0.424836473521636	[]	[]	2	hSpCas9	negative selection	2804988
35332834	35332857	19	+	27260157	RKO	viability	CCGGTGCACCTCAATGACAGTGG	CD22	ENSG00000012124	-0.382311334459626	[]	[]	-6	hSpCas9	negative selection	2813334
35336243	35336266	19	-	27260157	RKO	viability	CCCATGGTGACTCCACTGTGGGG	CD22	ENSG00000012124	-0.773845282612813	[]	[]	-7	hSpCas9	negative selection	2814506
35336307	35336330	19	-	27260157	RKO	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	0.497875714005585	[]	[]	2	hSpCas9	negative selection	2815133
35336129	35336152	19	+	27260157	RKO	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.00187039037408887	[]	[]	0	hSpCas9	negative selection	2835732
35336259	35336282	19	-	27260157	RKO	viability	GGCAGGTCACAATCTTCCCATGG	CD22	ENSG00000012124	-0.0404302149359909	[]	[]	0	hSpCas9	negative selection	2837395
35336134	35336157	19	-	27260157	RKO	viability	AGGAGCCACTGCAATTGGATCGG	CD22	ENSG00000012124	0.745880146838036	[]	[]	8	hSpCas9	negative selection	2838897
35337921	35337944	19	-	27260157	RKO	viability	GGTCCTTGGTCACTTCGCGCAGG	CD22	ENSG00000012124	-1.73968245550986	[]	[]	-9	hSpCas9	negative selection	2840714
35336120	35336143	19	-	27260157	RKO	viability	TTGGATCGGATACCCATAGCAGG	CD22	ENSG00000012124	0.487236146158389	[]	[]	2	hSpCas9	negative selection	2842845
35332830	35332853	19	-	27260157	RKO	viability	TGTCATTGAGGTGCACCGGGTGG	CD22	ENSG00000012124	0.0934018054311451	[]	[]	0	hSpCas9	negative selection	2844448
35337858	35337881	19	+	27260157	RKO	viability	CACGACGGTATCCTGGCTCAAGG	CD22	ENSG00000012124	0.118042121202326	[]	[]	0	hSpCas9	negative selection	2847182
35337843	35337866	19	+	27260157	RKO	viability	CAGCAACCCGGAGTACACGACGG	CD22	ENSG00000012124	-0.483358040524484	[]	[]	-6	hSpCas9	negative selection	2850991
35336102	35336125	19	-	27260157	RKO	viability	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.595685579959468	[]	[]	3	hSpCas9	negative selection	2852255
35332844	35332867	19	+	27260157	RKO	viability	TCAATGACAGTGGTCAGCTGGGG	CD22	ENSG00000012124	-1.08472116942408	[]	[]	-8	hSpCas9	negative selection	2874027
35336222	35336245	19	-	27260157	RKO	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.508531143611236	[]	[]	2	hSpCas9	negative selection	2874989
35332032	35332055	19	+	27260157	RKO	viability	CACGACACCATGCATCTCCTCGG	CD22	ENSG00000012124	0.895621720242441	[]	[]	8	hSpCas9	negative selection	2876524
35332638	35332661	19	-	27260157	RKO	viability	CTAGGGCTCTGTAGGTGCAGGGG	CD22	ENSG00000012124	0.0204540617851456	[]	[]	0	hSpCas9	negative selection	2877795
35337849	35337872	19	-	27260157	RKO	viability	AGGATACCGTCGTGTACTCCGGG	CD22	ENSG00000012124	0.103227798997337	[]	[]	0	hSpCas9	negative selection	2878054
35332715	35332738	19	-	27260157	SF268	viability	TCTTGTCCCATCAAACTTCGAGG	CD22	ENSG00000012124	-0.236320706375978	[]	[]	-2	hSpCas9	negative selection	2878401
35337918	35337941	19	+	27260157	SF268	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.480466311180514	[]	[]	7	hSpCas9	negative selection	2879316
35332595	35332618	19	+	27260157	SF268	viability	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	0.0661337496493407	[]	[]	0	hSpCas9	negative selection	2881118
35332834	35332857	19	+	27260157	SF268	viability	CCGGTGCACCTCAATGACAGTGG	CD22	ENSG00000012124	-0.599875367987657	[]	[]	-4	hSpCas9	negative selection	2889464
35336243	35336266	19	-	27260157	SF268	viability	CCCATGGTGACTCCACTGTGGGG	CD22	ENSG00000012124	-0.217615588193425	[]	[]	-2	hSpCas9	negative selection	2890636
35336307	35336330	19	-	27260157	SF268	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.259497947084699	[]	[]	-2	hSpCas9	negative selection	2891263
35336129	35336152	19	+	27260157	SF268	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-1.49306795713848	[]	[]	-8	hSpCas9	negative selection	2911862
35336259	35336282	19	-	27260157	SF268	viability	GGCAGGTCACAATCTTCCCATGG	CD22	ENSG00000012124	-1.7441164611567	[]	[]	-8	hSpCas9	negative selection	2913525
35336134	35336157	19	-	27260157	SF268	viability	AGGAGCCACTGCAATTGGATCGG	CD22	ENSG00000012124	0.332355461971105	[]	[]	4	hSpCas9	negative selection	2915027
35337921	35337944	19	-	27260157	SF268	viability	GGTCCTTGGTCACTTCGCGCAGG	CD22	ENSG00000012124	-2.58388147590968	[]	[]	-9	hSpCas9	negative selection	2916844
35336120	35336143	19	-	27260157	SF268	viability	TTGGATCGGATACCCATAGCAGG	CD22	ENSG00000012124	0.207212782087804	[]	[]	3	hSpCas9	negative selection	2918975
35332830	35332853	19	-	27260157	SF268	viability	TGTCATTGAGGTGCACCGGGTGG	CD22	ENSG00000012124	-0.393776059479417	[]	[]	-3	hSpCas9	negative selection	2920578
35337858	35337881	19	+	27260157	SF268	viability	CACGACGGTATCCTGGCTCAAGG	CD22	ENSG00000012124	-0.0523082103873965	[]	[]	0	hSpCas9	negative selection	2923312
35337843	35337866	19	+	27260157	SF268	viability	CAGCAACCCGGAGTACACGACGG	CD22	ENSG00000012124	-0.151992795747405	[]	[]	-1	hSpCas9	negative selection	2927121
35336102	35336125	19	-	27260157	SF268	viability	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.746034284535807	[]	[]	8	hSpCas9	negative selection	2928385
35332844	35332867	19	+	27260157	SF268	viability	TCAATGACAGTGGTCAGCTGGGG	CD22	ENSG00000012124	-1.3030258252229	[]	[]	-7	hSpCas9	negative selection	2950157
35336222	35336245	19	-	27260157	SF268	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.748836291055602	[]	[]	8	hSpCas9	negative selection	2951119
35332032	35332055	19	+	27260157	SF268	viability	CACGACACCATGCATCTCCTCGG	CD22	ENSG00000012124	0.467984819961824	[]	[]	7	hSpCas9	negative selection	2952654
35332638	35332661	19	-	27260157	SF268	viability	CTAGGGCTCTGTAGGTGCAGGGG	CD22	ENSG00000012124	0.359260056768266	[]	[]	4	hSpCas9	negative selection	2953925
35337849	35337872	19	-	27260157	SF268	viability	AGGATACCGTCGTGTACTCCGGG	CD22	ENSG00000012124	-0.10309190784947	[]	[]	-1	hSpCas9	negative selection	2954184
35340975	35340998	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTCATACCGGGTAACACTGGGG	CD22	ENSG00000012124	0.3983973855148962	[3,3]	[3,4]	8	hSpCas9	positive selection	2977610
35332816	35332839	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGCACACTGAGTATCCACCCGG	CD22	ENSG00000012124	-0.0821006664431135	[3,3]	[3,2]	-1	hSpCas9	positive selection	2977611
35336064	35336087	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGACTCTTGAATTTCTGGAGGG	CD22	ENSG00000012124	0.5399391911608349	[3,4]	[3,6]	9	hSpCas9	positive selection	2977612
35332765	35332788	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTTCCTTCTGAGCAGAAAAGGG	CD22	ENSG00000012124	0.04709638845738509	[4,4]	[2,3]	1	hSpCas9	positive selection	2977613
35340975	35340998	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTCATACCGGGTAACACTGGGG	CD22	ENSG00000012124	-0.10391916934324455	[3,3]	[1,2]	-1	hSpCas9	positive selection	3045468
35332816	35332839	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGCACACTGAGTATCCACCCGG	CD22	ENSG00000012124	-0.2598217128584873	[3,3]	[3,1]	-4	hSpCas9	positive selection	3045469
35336064	35336087	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGACTCTTGAATTTCTGGAGGG	CD22	ENSG00000012124	0.23563502934196018	[3,3]	[3,2]	4	hSpCas9	positive selection	3045470
35332765	35332788	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTTCCTTCTGAGCAGAAAAGGG	CD22	ENSG00000012124	-0.09998384283416778	[4,4]	[3,1]	-1	hSpCas9	positive selection	3045471
35332595	35332618		+	24336571	A375	resistance to PLX after 7 days	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	-0.14724492757576346	[69,65]	[59,61]	-5	hSpCas9	positive selection	3104015
35332903	35332926		+	24336571	A375	resistance to PLX after 7 days	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	-0.06465988252690469	[72,72]	[69,68]	-2	hSpCas9	positive selection	3104016
35336222	35336245		-	24336571	A375	resistance to PLX after 7 days	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.20749542330766457	[21,27]	[20,20]	-6	hSpCas9	positive selection	3104018
35336312	35336335		-	24336571	A375	resistance to PLX after 7 days	GTTCAGCTGCACCGTGTCATTGG	CD22	ENSG00000012124	0.10892634883199959	[60,56]	[57,67]	3	hSpCas9	positive selection	3104019
35332595	35332618		+	24336571	A375	resistance to PLX after 14 days	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	0.19389067803773452	[75,66]	[40,33]	2	hSpCas9	positive selection	3161808
35332903	35332926		+	24336571	A375	resistance to PLX after 14 days	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.12060665178478835	[78,97]	[43,45]	1	hSpCas9	positive selection	3161809
35336222	35336245		-	24336571	A375	resistance to PLX after 14 days	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.4122332824349748	[12,21]	[5,5]	-5	hSpCas9	positive selection	3161811
35336312	35336335		-	24336571	A375	resistance to PLX after 14 days	GTTCAGCTGCACCGTGTCATTGG	CD22	ENSG00000012124	0.45279265201272656	[56,57]	[38,33]	4	hSpCas9	positive selection	3161812
35332595	35332618		+	24336571	A375	viability after 7 days	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	-0.24884669164081474	[84]	[69,65]	-4	hSpCas9	negative selection	3219601
35332903	35332926		+	24336571	A375	viability after 7 days	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.19990845629002418	[66]	[72,72]	3	hSpCas9	negative selection	3219602
35336222	35336245		-	24336571	A375	viability after 7 days	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.49058340156313884	[36]	[21,27]	-6	hSpCas9	negative selection	3219604
35336312	35336335		-	24336571	A375	viability after 7 days	GTTCAGCTGCACCGTGTCATTGG	CD22	ENSG00000012124	0.09617956514376802	[57]	[60,56]	1	hSpCas9	negative selection	3219605
35332595	35332618		+	24336571	A375	viability after 14 days	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	-0.16498267676749778	[84]	[75,66]	-2	hSpCas9	negative selection	3277394
35332903	35332926		+	24336571	A375	viability after 14 days	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.4840517739926562	[66]	[78,97]	6	hSpCas9	negative selection	3277395
35336222	35336245		-	24336571	A375	viability after 14 days	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.931364837788881	[36]	[12,21]	-8	hSpCas9	negative selection	3277397
35336312	35336335		-	24336571	A375	viability after 14 days	GTTCAGCTGCACCGTGTCATTGG	CD22	ENSG00000012124	0.07553216523108874	[57]	[56,57]	1	hSpCas9	negative selection	3277398
35337850	35337873	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	0.11844376440068302	[130,150]	[0,0]	0	hSpCas9	positive selection	3341979
35332903	35332926	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	-1.3380105063091872	[351,421]	[0,0]	-8	hSpCas9	positive selection	3341980
35332539	35332562	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.7905199826979775	[80,95]	[0,0]	4	hSpCas9	positive selection	3341981
35336222	35336245	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	3.4499712893882313	[13,13]	[0,0]	9	hSpCas9	positive selection	3361208
35337918	35337941	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.41183616050145994	[114,114]	[0,0]	2	hSpCas9	positive selection	3361209
35338183	35338206	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	0.22390320990838475	[130,130]	[0,0]	1	hSpCas9	positive selection	3361210
35340975	35340998	19	-	26780180	HT29	viability (Avana library 4 designs)	ATTCATACCGGGTAACACTGGGG	CD22	ENSG00000012124	2.38345192562885	[]	[]	8	hSpCas9	negative selection	3413913
35332815	35332838	19	+	26780180	HT29	viability (Avana library 4 designs)	CTGCACACTGAGTATCCACCCGG	CD22	ENSG00000012124	1.47900422611013	[]	[]	6	hSpCas9	negative selection	3413914
35336064	35336087	19	-	26780180	HT29	viability (Avana library 4 designs)	GGGACTCTTGAATTTCTGGAGGG	CD22	ENSG00000012124	-0.0204311453990078	[]	[]	0	hSpCas9	negative selection	3413915
35332764	35332787	19	+	26780180	HT29	viability (Avana library 4 designs)	GGTTCCTTCTGAGCAGAAAAGGG	CD22	ENSG00000012124	0.747120427268787	[]	[]	3	hSpCas9	negative selection	3413916
35336064	35336087	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGACTCTTGAATTTCTGGAGGG	CD22	ENSG00000012124	-2.02339707679972	[]	[]	-2	hSpCas9	negative selection	3490173
35332815	35332838	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCACACTGAGTATCCACCCGG	CD22	ENSG00000012124	0.446911610124885	[]	[]	0	hSpCas9	negative selection	3490174
35332764	35332787	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTCCTTCTGAGCAGAAAAGGG	CD22	ENSG00000012124	-2.01034189168811	[]	[]	-2	hSpCas9	negative selection	3490175
35340975	35340998	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATTCATACCGGGTAACACTGGGG	CD22	ENSG00000012124	-1.63809841788769	[]	[]	-2	hSpCas9	negative selection	3490176
35336279	35336302	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAGCTTCAGGATGCAGATGGG	CD22	ENSG00000012124	3.85686165252401	[]	[]	6	hSpCas9	negative selection	3490177
35332638	35332661	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGGGCTCTGTAGGTGCAGGGG	CD22	ENSG00000012124	3.86459685760316	[]	[]	6	hSpCas9	negative selection	3490178
35336064	35336087	19	-	26780180	A375	viability (Avana lentiGuide)	GGGACTCTTGAATTTCTGGAGGG	CD22	ENSG00000012124	-3.00897094107806	[]	[]	-5	hSpCas9	negative selection	3598832
35332815	35332838	19	+	26780180	A375	viability (Avana lentiGuide)	CTGCACACTGAGTATCCACCCGG	CD22	ENSG00000012124	4.7186124977556	[]	[]	4	hSpCas9	negative selection	3598833
35332764	35332787	19	+	26780180	A375	viability (Avana lentiGuide)	GGTTCCTTCTGAGCAGAAAAGGG	CD22	ENSG00000012124	0.52897062332699	[]	[]	0	hSpCas9	negative selection	3598834
35340975	35340998	19	-	26780180	A375	viability (Avana lentiGuide)	ATTCATACCGGGTAACACTGGGG	CD22	ENSG00000012124	3.58952703713112	[]	[]	3	hSpCas9	negative selection	3598835
35336279	35336302	19	+	26780180	A375	viability (Avana lentiGuide)	GCCAGCTTCAGGATGCAGATGGG	CD22	ENSG00000012124	-7.10081479411359	[]	[]	-9	hSpCas9	negative selection	3598836
35332638	35332661	19	-	26780180	A375	viability (Avana lentiGuide)	CTAGGGCTCTGTAGGTGCAGGGG	CD22	ENSG00000012124	8.54262181264207	[]	[]	6	hSpCas9	negative selection	3598837
35336064	35336087	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGACTCTTGAATTTCTGGAGGG	CD22	ENSG00000012124	-0.09540700395993267	[5]	[5,4]	-1	hSpCas9	positive selection	3707491
35332815	35332838	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCACACTGAGTATCCACCCGG	CD22	ENSG00000012124	-0.4981878976556862	[4]	[3,1]	-6	hSpCas9	positive selection	3707492
35332764	35332787	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTCCTTCTGAGCAGAAAAGGG	CD22	ENSG00000012124	-0.1201026448074689	[5]	[5,3]	-2	hSpCas9	positive selection	3707493
35340975	35340998	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTCATACCGGGTAACACTGGGG	CD22	ENSG00000012124	-0.4540737947621713	[5]	[2,4]	-6	hSpCas9	positive selection	3707494
35336279	35336302	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAGCTTCAGGATGCAGATGGG	CD22	ENSG00000012124	0.24982870268573243	[4]	[5,5]	7	hSpCas9	positive selection	3707495
35332638	35332661	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGGGCTCTGTAGGTGCAGGGG	CD22	ENSG00000012124	0.22768938398321573	[5]	[6,6]	6	hSpCas9	positive selection	3707496
35336064	35336087	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGACTCTTGAATTTCTGGAGGG	CD22	ENSG00000012124	0.22120608262392433	[5]	[5,5]	5	hSpCas9	positive selection	3816098
35332815	35332838	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCACACTGAGTATCCACCCGG	CD22	ENSG00000012124	-0.05790447143170585	[5]	[5,3]	-1	hSpCas9	positive selection	3816099
35332764	35332787	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTCCTTCTGAGCAGAAAAGGG	CD22	ENSG00000012124	0.18071784443659253	[5]	[5,5]	4	hSpCas9	positive selection	3816100
35340975	35340998	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTCATACCGGGTAACACTGGGG	CD22	ENSG00000012124	0.214658725747791	[5]	[4,5]	5	hSpCas9	positive selection	3816101
35336279	35336302	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAGCTTCAGGATGCAGATGGG	CD22	ENSG00000012124	0.38255039088732373	[4]	[5,5]	9	hSpCas9	positive selection	3816102
35332638	35332661	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGGGCTCTGTAGGTGCAGGGG	CD22	ENSG00000012124	0.001625814615454968	[6]	[6,4]	0	hSpCas9	positive selection	3816103
35337918	35337941	19	+	26780180	A375	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	1.64415047420226	[]	[]	8	hSpCas9	negative selection	3924275
35337850	35337873	19	-	26780180	A375	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	1.73448327489675	[]	[]	9	hSpCas9	negative selection	3924276
35332903	35332926	19	+	26780180	A375	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	1.4412557635076	[]	[]	8	hSpCas9	negative selection	3924277
35336222	35336245	19	-	26780180	A375	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.819989883816659	[]	[]	3	hSpCas9	negative selection	3924278
35332539	35332562	19	+	26780180	A375	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.62444902030413	[]	[]	2	hSpCas9	negative selection	3924279
35338183	35338206	19	-	26780180	A375	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	1.73208107243208	[]	[]	9	hSpCas9	negative selection	3924280
35337918	35337941	19	+	26780180	HT29	viability (GeCKOv2 library)	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	1.05114979938047	[]	[]	5	hSpCas9	negative selection	4032241
35337850	35337873	19	-	26780180	HT29	viability (GeCKOv2 library)	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	2.42335849101176	[]	[]	9	hSpCas9	negative selection	4032242
35332903	35332926	19	+	26780180	HT29	viability (GeCKOv2 library)	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	2.01469181975644	[]	[]	9	hSpCas9	negative selection	4032243
35336222	35336245	19	-	26780180	HT29	viability (GeCKOv2 library)	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.888375518825747	[]	[]	4	hSpCas9	negative selection	4032244
35332539	35332562	19	+	26780180	HT29	viability (GeCKOv2 library)	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.202262477492002	[]	[]	0	hSpCas9	negative selection	4032245
35338183	35338206	19	-	26780180	HT29	viability (GeCKOv2 library)	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	1.63280554745905	[]	[]	8	hSpCas9	negative selection	4032246
35332595	35332618	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	0.2951976169538164	[5]	[4,5]	7	hSpCas9	positive selection	4126004
35332903	35332926	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.24318727212570135	[5]	[4,5]	6	hSpCas9	positive selection	4126005
35336222	35336245	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.11492816913231588	[4]	[3,2]	-3	hSpCas9	positive selection	4126007
35336312	35336335	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTTCAGCTGCACCGTGTCATTGG	CD22	ENSG00000012124	0.3065224578508997	[5]	[4,5]	7	hSpCas9	positive selection	4126008
35332595	35332618	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCCTGAAACCCTCTACGCCTGG	CD22	ENSG00000012124	1.0294905609356326	[5]	[5,4,5,4]	7	hSpCas9	positive selection	4190026
35332903	35332926	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	1.160502045385483	[6]	[5,6,5,5]	8	hSpCas9	positive selection	4190027
35336222	35336245	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	1.1340402564578802	[5]	[4,4,3,5]	8	hSpCas9	positive selection	4190029
35336312	35336335	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTTCAGCTGCACCGTGTCATTGG	CD22	ENSG00000012124	0.6303344151309964	[5]	[4,2,4,3]	4	hSpCas9	positive selection	4190030
35337850	35337873	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	0.04228176181407606	[3]	[2,3]	0	hSpCas9	positive selection	4261995
35332903	35332926	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	-0.27476379976715753	[4]	[3,1]	-5	hSpCas9	positive selection	4261996
35332539	35332562	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.14749263546782893	[2]	[3,1]	3	hSpCas9	positive selection	4261997
35336222	35336245	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.18644225061830078	[1]	[0,1]	4	hSpCas9	positive selection	4326272
35337918	35337941	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.4819427800927418	[2]	[1,0]	-8	hSpCas9	positive selection	4326273
35338183	35338206	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.3464781799548151	[2]	[1,0]	-6	hSpCas9	positive selection	4326274
35340899	35340921	19	-	27760321	OCIAML3	viability	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	0.07762501431966401	[370,279]	[242,296]	0	hSpCas9	negative selection	4387295
35340916	35340938	19	-	27760321	OCIAML3	viability	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.7448589032651443	[565,476]	[538,865]	8	hSpCas9	negative selection	4387296
35340976	35340998	19	-	27760321	OCIAML3	viability	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	0.5618215613437026	[204,189]	[145,334]	6	hSpCas9	negative selection	4387297
35341079	35341101	19	-	27760321	OCIAML3	viability	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.7462401003535895	[668,536]	[292,261]	-6	hSpCas9	negative selection	4387298
35341342	35341364	19	+	27760321	OCIAML3	viability	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.7462397595345366	[749,619]	[690,1159]	8	hSpCas9	negative selection	4387299
35340899	35340921	19	-	27760321	OCIAML2	viability	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	0.3279729492364679	[370,279]	[332,320]	4	hSpCas9	negative selection	4470758
35340916	35340938	19	-	27760321	OCIAML2	viability	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.2979416729697026	[565,476]	[432,626]	4	hSpCas9	negative selection	4470759
35340976	35340998	19	-	27760321	OCIAML2	viability	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	0.953091387521074	[204,189]	[317,297]	9	hSpCas9	negative selection	4470760
35341079	35341101	19	-	27760321	OCIAML2	viability	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.19197376795677157	[668,536]	[358,510]	-2	hSpCas9	negative selection	4470761
35341342	35341364	19	+	27760321	OCIAML2	viability	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.6999307871004966	[749,619]	[880,915]	8	hSpCas9	negative selection	4470762
35340899	35340921	19	-	27760321	MV411	viability	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	1.1662570238115808	[370,279]	[621,261]	8	hSpCas9	negative selection	4554221
35340916	35340938	19	-	27760321	MV411	viability	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	1.0414605284352805	[565,476]	[835,509]	7	hSpCas9	negative selection	4554222
35340976	35340998	19	-	27760321	MV411	viability	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	1.485521100286093	[204,189]	[376,346]	9	hSpCas9	negative selection	4554223
35341079	35341101	19	-	27760321	MV411	viability	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-1.8954352354847546	[668,536]	[43,199]	-8	hSpCas9	negative selection	4554224
35341342	35341364	19	+	27760321	MV411	viability	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.5195921308035921	[749,619]	[754,479]	4	hSpCas9	negative selection	4554225
35340899	35340921	19	-	27760321	HL60	viability	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	0.4945487195763752	[370,279]	[256,492]	6	hSpCas9	negative selection	4637684
35340916	35340938	19	-	27760321	HL60	viability	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.40785736669287814	[565,476]	[515,612]	5	hSpCas9	negative selection	4637685
35340976	35340998	19	-	27760321	HL60	viability	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	0.34129933574226534	[204,189]	[201,206]	4	hSpCas9	negative selection	4637686
35341079	35341101	19	-	27760321	HL60	viability	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.6048161797010476	[668,536]	[389,249]	-6	hSpCas9	negative selection	4637687
35341342	35341364	19	+	27760321	HL60	viability	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.030350385629280052	[749,619]	[564,572]	0	hSpCas9	negative selection	4637688
35340899	35340921	19	-	27760321	HT1080	viability	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	0.430180424714604	[279,218]	[79,192]	2	hSpCas9	negative selection	4721147
35340916	35340938	19	-	27760321	HT1080	viability	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.6928242714910285	[476,371]	[269,276]	3	hSpCas9	negative selection	4721148
35340976	35340998	19	-	27760321	HT1080	viability	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	2.296552803374058	[189,147]	[271,394]	9	hSpCas9	negative selection	4721149
35341079	35341101	19	-	27760321	HT1080	viability	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	0.1192213914271747	[536,418]	[181,233]	0	hSpCas9	negative selection	4721150
35341342	35341364	19	+	27760321	HT1080	viability	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.44145664549549857	[619,483]	[374,214]	2	hSpCas9	negative selection	4721151
35340899	35340921	19	-	27760321	HT29	viability after 7 days	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	0.25412469450049	[279,218]	[474,350,335]	4	hSpCas9	negative selection	4804610
35340916	35340938	19	-	27760321	HT29	viability after 7 days	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.20719445165055625	[476,371]	[776,560,573]	3	hSpCas9	negative selection	4804611
35340976	35340998	19	-	27760321	HT29	viability after 7 days	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	0.38962605999299027	[189,147]	[279,262,308]	6	hSpCas9	negative selection	4804612
35341079	35341101	19	-	27760321	HT29	viability after 7 days	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.2005177892277906	[536,418]	[649,495,475]	-3	hSpCas9	negative selection	4804613
35341342	35341364	19	+	27760321	HT29	viability after 7 days	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.8120042059609852	[619,483]	[1431,741,1577]	9	hSpCas9	negative selection	4804614
35340899	35340921	19	-	27760321	HT29	viability after 25 days	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	-0.03801035602777081	[279,218]	[246,402,173]	0	hSpCas9	negative selection	4888073
35340916	35340938	19	-	27760321	HT29	viability after 25 days	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.5038339493118604	[476,371]	[576,593,922]	5	hSpCas9	negative selection	4888074
35340976	35340998	19	-	27760321	HT29	viability after 25 days	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	0.4543640827600417	[189,147]	[247,233,317]	5	hSpCas9	negative selection	4888075
35341079	35341101	19	-	27760321	HT29	viability after 25 days	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.5922288889003817	[536,418]	[331,362,396]	-5	hSpCas9	negative selection	4888076
35341342	35341364	19	+	27760321	HT29	viability after 25 days	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.503745457546034	[619,483]	[816,974,894]	5	hSpCas9	negative selection	4888077
35340899	35340921	19	-	27760321	HT29	viability after 22 days	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	-0.24874792223044406	[279,218]	[118,337,274]	-3	hSpCas9	negative selection	4971536
35340916	35340938	19	-	27760321	HT29	viability after 22 days	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.48863290086665334	[476,371]	[661,746,656]	5	hSpCas9	negative selection	4971537
35340976	35340998	19	-	27760321	HT29	viability after 22 days	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	0.4156227124791152	[189,147]	[302,274,201]	4	hSpCas9	negative selection	4971538
35341079	35341101	19	-	27760321	HT29	viability after 22 days	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.17922786067945465	[536,418]	[563,410,486]	-2	hSpCas9	negative selection	4971539
35341342	35341364	19	+	27760321	HT29	viability after 22 days	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.7696735921081242	[619,483]	[794,947,1532]	8	hSpCas9	negative selection	4971540
35340899	35340921	19	-	27760321	HT29	viability after 19 days	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	-0.07105965746575482	[279,218]	[148,354,296]	0	hSpCas9	negative selection	5054999
35340916	35340938	19	-	27760321	HT29	viability after 19 days	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.652100389878713	[476,371]	[741,1049,503]	6	hSpCas9	negative selection	5055000
35340976	35340998	19	-	27760321	HT29	viability after 19 days	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	0.030134964997615477	[189,147]	[253,231,114]	0	hSpCas9	negative selection	5055001
35341079	35341101	19	-	27760321	HT29	viability after 19 days	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	0.03920670320982311	[536,418]	[603,436,644]	0	hSpCas9	negative selection	5055002
35341342	35341364	19	+	27760321	HT29	viability after 19 days	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.9375966970754473	[619,483]	[1591,1245,842]	8	hSpCas9	negative selection	5055003
35340899	35340921	19	-	27760321	HT29	viability after 16 days	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	0.19102175973251106	[279,218]	[237,296,413]	2	hSpCas9	negative selection	5138462
35340916	35340938	19	-	27760321	HT29	viability after 16 days	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.3416034205467048	[476,371]	[713,481,622]	4	hSpCas9	negative selection	5138463
35340976	35340998	19	-	27760321	HT29	viability after 16 days	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	0.6813184692666061	[189,147]	[241,290,370]	7	hSpCas9	negative selection	5138464
35341079	35341101	19	-	27760321	HT29	viability after 16 days	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.31950915719010475	[536,418]	[706,384,220]	-3	hSpCas9	negative selection	5138465
35341342	35341364	19	+	27760321	HT29	viability after 16 days	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	1.0797217495283382	[619,483]	[1446,1658,813]	9	hSpCas9	negative selection	5138466
35340899	35340921	19	-	27760321	HT29	viability after 13 days	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	0.08609181526077253	[279,218]	[280,352,288]	1	hSpCas9	negative selection	5221925
35340916	35340938	19	-	27760321	HT29	viability after 13 days	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.29124645796880333	[476,371]	[566,590,646]	3	hSpCas9	negative selection	5221926
35340976	35340998	19	-	27760321	HT29	viability after 13 days	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	-0.017055918598399167	[189,147]	[249,170,161]	0	hSpCas9	negative selection	5221927
35341079	35341101	19	-	27760321	HT29	viability after 13 days	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.5204451552329558	[536,418]	[426,403,331]	-5	hSpCas9	negative selection	5221928
35341342	35341364	19	+	27760321	HT29	viability after 13 days	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.827984450259294	[619,483]	[1331,1063,1020]	9	hSpCas9	negative selection	5221929
35340899	35340921	19	-	27760321	HT29	viability after 10 days	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	-0.36535400713205257	[279,218]	[211,364,153]	-5	hSpCas9	negative selection	5305388
35340916	35340938	19	-	27760321	HT29	viability after 10 days	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.006124135074033976	[476,371]	[568,482,542]	0	hSpCas9	negative selection	5305389
35340976	35340998	19	-	27760321	HT29	viability after 10 days	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	0.08230602011873689	[189,147]	[225,260,184]	1	hSpCas9	negative selection	5305390
35341079	35341101	19	-	27760321	HT29	viability after 10 days	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.3961461829911621	[536,418]	[495,425,437]	-5	hSpCas9	negative selection	5305391
35341342	35341364	19	+	27760321	HT29	viability after 10 days	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.7797547575626996	[619,483]	[1214,1176,1157]	9	hSpCas9	negative selection	5305392
35340899	35340921	19	-	27760321	MOLM13	viability	ATGGGGTTTTGAATCACTGTGG	CD22	ENSG00000012124	-1.6587453016921425	[370,279]	[34,76]	-7	hSpCas9	negative selection	5388851
35340916	35340938	19	-	27760321	MOLM13	viability	CTCCTTCTCGAATCGGCATGGG	CD22	ENSG00000012124	0.8776341306943851	[565,476]	[570,510]	6	hSpCas9	negative selection	5388852
35340976	35340998	19	-	27760321	MOLM13	viability	ATTCATACCGGGTAACACTGGG	CD22	ENSG00000012124	-0.8648300615325049	[204,189]	[71,51]	-5	hSpCas9	negative selection	5388853
35341079	35341101	19	-	27760321	MOLM13	viability	CAACTATTACAAGCTGCGCAGG	CD22	ENSG00000012124	-0.3571980352931835	[668,536]	[262,264]	-2	hSpCas9	negative selection	5388854
35341342	35341364	19	+	27760321	MOLM13	viability	GATGCCCCCCGAGACGTGAGGG	CD22	ENSG00000012124	0.30980097786332605	[749,619]	[511,446]	2	hSpCas9	negative selection	5388855
35329381	35329404	19	-	27661255	K562	viability	GCAAGGAGGATGCTCAAGACAGG	CD22	ENSG00000012124	0.20980922695048293	[567,512]	[550,456]	7	dCas9-KRAB	negative selection	5469382
35329479	35329502	19	-	27661255	K562	viability	GAGGGCCTTGCAGAACCTTGGGG	CD22	ENSG00000012124	0.17123541779342377	[1141,1025]	[1072,894]	6	dCas9-KRAB	negative selection	5469383
35329612	35329635	19	-	27661255	K562	viability	GAGCACAGGAGTAGGGCCCCAGG	CD22	ENSG00000012124	0.33351992468702596	[771,848]	[889,749]	9	dCas9-KRAB	negative selection	5469384
35329619	35329642	19	-	27661255	K562	viability	GTCTCTGGAGCACAGGAGTAGGG	CD22	ENSG00000012124	0.32436440364289054	[389,463]	[435,416]	9	dCas9-KRAB	negative selection	5469385
35337850	35337873	19	-	27260156	BXPC3	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.03925322617679139	[841]	[709,954,860,911]	-1	hSpCas9	negative selection	5534455
35332903	35332926	19	+	27260156	BXPC3	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.24288784958214227	[1078]	[1218,1245,1350,1560]	5	hSpCas9	negative selection	5534456
35332539	35332562	19	+	27260156	BXPC3	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.4750212792328308	[278]	[276,397,433,541]	8	hSpCas9	negative selection	5534457
35336222	35336245	19	-	27260156	BXPC3	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.0014334854375039896	[79]	[61,97,85,89]	0	hSpCas9	negative selection	5598732
35337918	35337941	19	+	27260156	BXPC3	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.11294852783400822	[340]	[303,339,422,498]	2	hSpCas9	negative selection	5598733
35338183	35338206	19	-	27260156	BXPC3	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-7.724840689160573e-05	[367]	[346,284,515,402]	0	hSpCas9	negative selection	5598734
35337850	35337873	19	-	27260156	A673	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.3669893547838367	[841]	[827,745,800,763]	-7	hSpCas9	negative selection	5655706
35332903	35332926	19	+	27260156	A673	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.20275824514652485	[1078]	[1310,1430,1665,1534]	5	hSpCas9	negative selection	5655707
35332539	35332562	19	+	27260156	A673	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.3211804708615288	[278]	[456,358,430,432]	7	hSpCas9	negative selection	5655708
35336222	35336245	19	-	27260156	A673	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.2873637949450294	[79]	[127,108,161,67]	6	hSpCas9	negative selection	5719983
35337918	35337941	19	+	27260156	A673	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.07514744552390706	[340]	[440,354,411,524]	1	hSpCas9	negative selection	5719984
35338183	35338206	19	-	27260156	A673	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.37569464715853856	[367]	[384,306,387,283]	-7	hSpCas9	negative selection	5719985
35337850	35337873	19	-	27260156	A375	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.2439222773520595	[841]	[765,1055,756,776]	-4	hSpCas9	negative selection	5776957
35332903	35332926	19	+	27260156	A375	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.34988751786082783	[1078]	[1912,1853,1561,1177]	5	hSpCas9	negative selection	5776958
35332539	35332562	19	+	27260156	A375	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.4075031212721549	[278]	[392,549,512,302]	6	hSpCas9	negative selection	5776959
35336222	35336245	19	-	27260156	A375	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.25662725658288243	[79]	[103,77,45,83]	-4	hSpCas9	negative selection	5841234
35337918	35337941	19	+	27260156	A375	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.24670455390073603	[340]	[304,414,312,320]	-4	hSpCas9	negative selection	5841235
35338183	35338206	19	-	27260156	A375	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-1.358675800113331	[367]	[151,224,117,180]	-9	hSpCas9	negative selection	5841236
35337850	35337873	19	-	27260156	COLO741	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.4832388594793583	[841]	[885,608,817]	-8	hSpCas9	negative selection	5898208
35332903	35332926	19	+	27260156	COLO741	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.3918642921523501	[1078]	[1960,1898,1591]	7	hSpCas9	negative selection	5898209
35332539	35332562	19	+	27260156	COLO741	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.25990673923038987	[278]	[457,394,428]	5	hSpCas9	negative selection	5898210
35336222	35336245	19	-	27260156	COLO741	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.06805455948076267	[79]	[70,108,135]	1	hSpCas9	negative selection	5962485
35337918	35337941	19	+	27260156	COLO741	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.07208236220089642	[340]	[526,424,307]	-1	hSpCas9	negative selection	5962486
35338183	35338206	19	-	27260156	COLO741	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.2918530965019693	[367]	[312,329,493]	-6	hSpCas9	negative selection	5962487
35337850	35337873	19	-	27260156	CAL120	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.3209998645523464	[841]	[827,997,690]	-5	hSpCas9	negative selection	6019459
35332903	35332926	19	+	27260156	CAL120	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.34320949026130787	[1078]	[1279,1864,1896]	5	hSpCas9	negative selection	6019460
35332539	35332562	19	+	27260156	CAL120	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.7834074854316119	[278]	[589,417,779]	9	hSpCas9	negative selection	6019461
35336222	35336245	19	-	27260156	CAL120	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.3937399733829836	[79]	[77,42,260]	6	hSpCas9	negative selection	6083736
35337918	35337941	19	+	27260156	CAL120	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.19622049091080923	[340]	[325,667,440]	3	hSpCas9	negative selection	6083737
35338183	35338206	19	-	27260156	CAL120	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.22930861075898307	[367]	[335,518,309]	-3	hSpCas9	negative selection	6083738
35337850	35337873	19	-	27260156	CADOES1	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.24036986945578998	[841]	[662,552,579,862]	-4	hSpCas9	negative selection	6140710
35332903	35332926	19	+	27260156	CADOES1	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.27771226440967745	[1078]	[1109,1290,984,1490]	5	hSpCas9	negative selection	6140711
35332539	35332562	19	+	27260156	CADOES1	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.37267237744731274	[278]	[332,344,352,311]	6	hSpCas9	negative selection	6140712
35336222	35336245	19	-	27260156	CADOES1	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.5511179867120672	[79]	[54,94,155,130]	8	hSpCas9	negative selection	6204987
35337918	35337941	19	+	27260156	CADOES1	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.259479352629252	[340]	[302,352,237,161]	-4	hSpCas9	negative selection	6204988
35338183	35338206	19	-	27260156	CADOES1	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.4809989968336527	[367]	[317,187,269,202]	-7	hSpCas9	negative selection	6204989
35337850	35337873	19	-	27260156	EWS502	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.22296059759751863	[841]	[812,818,819,580]	-4	hSpCas9	negative selection	6261961
35332903	35332926	19	+	27260156	EWS502	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.1953541902785032	[1078]	[987,1352,1534,1399]	3	hSpCas9	negative selection	6261962
35332539	35332562	19	+	27260156	EWS502	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.19145088195626825	[278]	[277,238,315,540]	3	hSpCas9	negative selection	6261963
35336222	35336245	19	-	27260156	EWS502	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.09547080330920421	[79]	[31,113,103,70]	-2	hSpCas9	negative selection	6326238
35337918	35337941	19	+	27260156	EWS502	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.524743301610439	[340]	[267,194,337,199]	-7	hSpCas9	negative selection	6326239
35338183	35338206	19	-	27260156	EWS502	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.3964830234927316	[367]	[216,286,372,318]	-6	hSpCas9	negative selection	6326240
35337850	35337873	19	-	27260156	EW8	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.30170242174836037	[841]	[883,592,387,412]	-5	hSpCas9	negative selection	6383212
35332903	35332926	19	+	27260156	EW8	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.11081716642195838	[1078]	[1093,1133,797,790]	2	hSpCas9	negative selection	6383213
35332539	35332562	19	+	27260156	EW8	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	-0.3035263949471758	[278]	[302,180,139,128]	-5	hSpCas9	negative selection	6383214
35336222	35336245	19	-	27260156	EW8	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-1.2142111486603455	[79]	[4,58,11,35]	-9	hSpCas9	negative selection	6447489
35337918	35337941	19	+	27260156	EW8	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.9522258161324775	[340]	[197,108,111,162]	-9	hSpCas9	negative selection	6447490
35338183	35338206	19	-	27260156	EW8	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.6389662108632086	[367]	[130,286,175,167]	-8	hSpCas9	negative selection	6447491
35337850	35337873	19	-	27260156	CORL105	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.4206652997251655	[841]	[641,564,958,813]	-6	hSpCas9	negative selection	6504463
35332903	35332926	19	+	27260156	CORL105	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.13022880835778317	[1078]	[1455,1184,1673,1266]	2	hSpCas9	negative selection	6504464
35332539	35332562	19	+	27260156	CORL105	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.017525389141667458	[278]	[363,350,284,315]	0	hSpCas9	negative selection	6504465
35336222	35336245	19	-	27260156	CORL105	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.19716403899892532	[79]	[90,67,85,180]	3	hSpCas9	negative selection	6568740
35337918	35337941	19	+	27260156	CORL105	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.021735412680879196	[340]	[511,351,386,325]	0	hSpCas9	negative selection	6568741
35338183	35338206	19	-	27260156	CORL105	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.1113063671143259	[367]	[454,386,426,332]	-2	hSpCas9	negative selection	6568742
35337850	35337873	19	-	27260156	HS294T	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.16837994845239868	[841]	[285,242,364,260]	-2	hSpCas9	negative selection	6625714
35332903	35332926	19	+	27260156	HS294T	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.5666372252324738	[1078]	[569,753,579,554]	7	hSpCas9	negative selection	6625715
35332539	35332562	19	+	27260156	HS294T	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.2599499516758322	[278]	[64,157,111,197]	3	hSpCas9	negative selection	6625716
35336222	35336245	19	-	27260156	HS294T	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.8696214513817195	[79]	[17,13,16,18]	-8	hSpCas9	negative selection	6689991
35337918	35337941	19	+	27260156	HS294T	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.4011096306940976	[340]	[69,108,115,107]	-5	hSpCas9	negative selection	6689992
35338183	35338206	19	-	27260156	HS294T	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	0.5607407419242039	[367]	[95,526,80,119]	7	hSpCas9	negative selection	6689993
35337850	35337873	19	-	27260156	HCC44	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.02454238920378482	[841]	[1067,855,921,912]	0	hSpCas9	negative selection	6746965
35332903	35332926	19	+	27260156	HCC44	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.25714115240557756	[1078]	[1568,1424,1588,1281]	4	hSpCas9	negative selection	6746966
35332539	35332562	19	+	27260156	HCC44	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.6498250763493597	[278]	[590,376,552,490]	9	hSpCas9	negative selection	6746967
35336222	35336245	19	-	27260156	HCC44	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.18612524222614857	[79]	[45,125,86,50]	-3	hSpCas9	negative selection	6811242
35337918	35337941	19	+	27260156	HCC44	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.28850628243059945	[340]	[616,398,557,348]	5	hSpCas9	negative selection	6811243
35338183	35338206	19	-	27260156	HCC44	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	0.09212461089959179	[367]	[487,420,549,340]	1	hSpCas9	negative selection	6811244
35337850	35337873	19	-	27260156	G402	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.36142385188384235	[841]	[721,719,811,919]	-4	hSpCas9	negative selection	6868216
35332903	35332926	19	+	27260156	G402	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.5847800284553859	[1078]	[2547,1872,2402,1182]	7	hSpCas9	negative selection	6868217
35332539	35332562	19	+	27260156	G402	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.26611954482958966	[278]	[594,259,365,431]	3	hSpCas9	negative selection	6868218
35336222	35336245	19	-	27260156	G402	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.7547713670125518	[79]	[79,68,69,17]	-7	hSpCas9	negative selection	6932493
35337918	35337941	19	+	27260156	G402	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.32992904130979533	[340]	[345,256,1050,400]	4	hSpCas9	negative selection	6932494
35338183	35338206	19	-	27260156	G402	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-1.1365334831277183	[367]	[125,395,173,123]	-8	hSpCas9	negative selection	6932495
35337850	35337873	19	-	27260156	L33	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.21950926246455282	[841]	[716,302,511,622]	-5	hSpCas9	negative selection	6989467
35332903	35332926	19	+	27260156	L33	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.5131133236119612	[1078]	[1497,655,973,1511]	8	hSpCas9	negative selection	6989468
35332539	35332562	19	+	27260156	L33	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.4436665231654019	[278]	[411,168,222,337]	8	hSpCas9	negative selection	6989469
35336222	35336245	19	-	27260156	L33	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.3914347643514988	[79]	[59,20,32,79]	-7	hSpCas9	negative selection	7053744
35337918	35337941	19	+	27260156	L33	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.09533133890902801	[340]	[431,165,221,265]	2	hSpCas9	negative selection	7053745
35338183	35338206	19	-	27260156	L33	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.14863572766194272	[367]	[264,127,234,377]	-3	hSpCas9	negative selection	7053746
35337850	35337873	19	-	27260156	K562	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	0.45568308928134615	[841]	[969,1144,659,1289]	6	hSpCas9	negative selection	7110718
35332903	35332926	19	+	27260156	K562	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.33610593712192816	[1078]	[970,1728,1252,918]	4	hSpCas9	negative selection	7110719
35332539	35332562	19	+	27260156	K562	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.19912716648808337	[278]	[537,226,108,279]	2	hSpCas9	negative selection	7110720
35336222	35336245	19	-	27260156	K562	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-1.067260538941901	[79]	[34,1,45,48]	-8	hSpCas9	negative selection	7174995
35337918	35337941	19	+	27260156	K562	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.6860333605237028	[340]	[250,227,234,59]	-7	hSpCas9	negative selection	7174996
35338183	35338206	19	-	27260156	K562	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.8670504119056801	[367]	[123,184,352,62]	-7	hSpCas9	negative selection	7174997
35337850	35337873	19	-	27260156	HT29	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.29156333936890366	[841]	[989,842,813,718]	-5	hSpCas9	negative selection	7231969
35332903	35332926	19	+	27260156	HT29	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.1942927167834676	[1078]	[1649,1599,1449,1332]	4	hSpCas9	negative selection	7231970
35332539	35332562	19	+	27260156	HT29	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.4908641934578211	[278]	[418,710,395,401]	8	hSpCas9	negative selection	7231971
35336222	35336245	19	-	27260156	HT29	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.03173680770570453	[79]	[44,116,112,101]	0	hSpCas9	negative selection	7296246
35337918	35337941	19	+	27260156	HT29	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.24341916838029015	[340]	[322,436,333,313]	-5	hSpCas9	negative selection	7296247
35338183	35338206	19	-	27260156	HT29	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.7222910128016373	[367]	[330,196,273,277]	-8	hSpCas9	negative selection	7296248
35337850	35337873	19	-	27260156	MHHES1	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.2614056569823042	[841]	[1059,781,739,632]	-5	hSpCas9	negative selection	7353220
35332903	35332926	19	+	27260156	MHHES1	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.522982619326432	[1078]	[1602,1976,1894,1527]	8	hSpCas9	negative selection	7353221
35332539	35332562	19	+	27260156	MHHES1	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.6653193017633752	[278]	[559,368,708,369]	9	hSpCas9	negative selection	7353222
35336222	35336245	19	-	27260156	MHHES1	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.20765056586547992	[79]	[119,156,9,43]	-4	hSpCas9	negative selection	7417497
35337918	35337941	19	+	27260156	MHHES1	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.3580019409489158	[340]	[399,510,648,408]	6	hSpCas9	negative selection	7417498
35338183	35338206	19	-	27260156	MHHES1	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.37439923999897934	[367]	[332,227,326,364]	-6	hSpCas9	negative selection	7417499
35337850	35337873	19	-	27260156	MEWO	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.07098710785533524	[841]	[788,783,683]	-1	hSpCas9	negative selection	7474471
35332903	35332926	19	+	27260156	MEWO	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.14753108704500062	[1078]	[1237,1006,1132]	3	hSpCas9	negative selection	7474472
35332539	35332562	19	+	27260156	MEWO	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.26653510881619524	[278]	[349,286,311]	6	hSpCas9	negative selection	7474473
35336222	35336245	19	-	27260156	MEWO	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.9705444430803487	[79]	[192,133,121]	9	hSpCas9	negative selection	7538748
35337918	35337941	19	+	27260156	MEWO	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.12282892282994035	[340]	[364,262,264]	-3	hSpCas9	negative selection	7538749
35338183	35338206	19	-	27260156	MEWO	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.5029310797969171	[367]	[288,186,261]	-8	hSpCas9	negative selection	7538750
35337850	35337873	19	-	27260156	LNCAPCLONEFGC	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.29119659775818907	[841]	[543,666,693,596]	-4	hSpCas9	negative selection	7595722
35332903	35332926	19	+	27260156	LNCAPCLONEFGC	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.24477017049222072	[1078]	[884,1246,1378,1152]	4	hSpCas9	negative selection	7595723
35332539	35332562	19	+	27260156	LNCAPCLONEFGC	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.09402124065192263	[278]	[231,230,369,263]	1	hSpCas9	negative selection	7595724
35336222	35336245	19	-	27260156	LNCAPCLONEFGC	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.031274271782072205	[79]	[74,39,93,79]	0	hSpCas9	negative selection	7659999
35337918	35337941	19	+	27260156	LNCAPCLONEFGC	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.14274067531285833	[340]	[275,239,301,306]	-2	hSpCas9	negative selection	7660000
35338183	35338206	19	-	27260156	LNCAPCLONEFGC	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.6282337978369013	[367]	[198,258,208,191]	-7	hSpCas9	negative selection	7660001
35337850	35337873	19	-	27260156	PANC0327	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.04807881403015968	[841]	[760,954,331,817]	0	hSpCas9	negative selection	7716973
35332903	35332926	19	+	27260156	PANC0327	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.2921856809536818	[1078]	[1218,1094,1122,1270]	4	hSpCas9	negative selection	7716974
35332539	35332562	19	+	27260156	PANC0327	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.10961275107739576	[278]	[395,304,129,243]	1	hSpCas9	negative selection	7716975
35336222	35336245	19	-	27260156	PANC0327	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.4899081880866758	[79]	[63,46,64,27]	-6	hSpCas9	negative selection	7781250
35337918	35337941	19	+	27260156	PANC0327	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.3594791803903604	[340]	[327,313,406,509]	5	hSpCas9	negative selection	7781251
35338183	35338206	19	-	27260156	PANC0327	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.059339894366154056	[367]	[219,233,189,612]	-1	hSpCas9	negative selection	7781252
35337850	35337873	19	-	27260156	NCIH2009	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	0.14049376138124614	[841]	[1437,1236,1241]	2	hSpCas9	negative selection	7838224
35332903	35332926	19	+	27260156	NCIH2009	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.43352491458156783	[1078]	[2623,1466,2139]	6	hSpCas9	negative selection	7838225
35332539	35332562	19	+	27260156	NCIH2009	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.42853397064138254	[278]	[850,386,401]	6	hSpCas9	negative selection	7838226
35336222	35336245	19	-	27260156	NCIH2009	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.4847469371304558	[79]	[81,129,26]	-6	hSpCas9	negative selection	7902501
35337918	35337941	19	+	27260156	NCIH2009	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.011615907765887501	[340]	[714,358,392]	0	hSpCas9	negative selection	7902502
35338183	35338206	19	-	27260156	NCIH2009	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.6390123262275504	[367]	[413,357,233]	-7	hSpCas9	negative selection	7902503
35337850	35337873	19	-	27260156	NCIH1373	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	0.06351722936825954	[841]	[1450,554,1240,208]	0	hSpCas9	negative selection	7959475
35332903	35332926	19	+	27260156	NCIH1373	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	1.242073095987751	[1078]	[2266,1634,2422,1392]	9	hSpCas9	negative selection	7959476
35332539	35332562	19	+	27260156	NCIH1373	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.1983840301258616	[278]	[375,283,354,113]	2	hSpCas9	negative selection	7959477
35336222	35336245	19	-	27260156	NCIH1373	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.545401822197634	[79]	[135,31,31,15]	-5	hSpCas9	negative selection	8023752
35337918	35337941	19	+	27260156	NCIH1373	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-1.1377349285380736	[340]	[73,209,259,32]	-8	hSpCas9	negative selection	8023753
35338183	35338206	19	-	27260156	NCIH1373	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-1.0786112034326334	[367]	[234,309,79,38]	-8	hSpCas9	negative selection	8023754
35337850	35337873	19	-	27260156	PATU8902	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.20348294544922452	[841]	[737,1165,716,1595]	-2	hSpCas9	negative selection	8080726
35332903	35332926	19	+	27260156	PATU8902	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.43971375887418973	[1078]	[2132,2573,1485,2093]	4	hSpCas9	negative selection	8080727
35332539	35332562	19	+	27260156	PATU8902	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	-0.150790163901115	[278]	[279,454,364,286]	-1	hSpCas9	negative selection	8080728
35336222	35336245	19	-	27260156	PATU8902	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.1862600158538772	[79]	[26,8,130,231]	-2	hSpCas9	negative selection	8145003
35337918	35337941	19	+	27260156	PATU8902	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.18535331449804343	[340]	[396,421,160,799]	-2	hSpCas9	negative selection	8145004
35338183	35338206	19	-	27260156	PATU8902	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-2.1379854330302552	[367]	[12,35,280,89]	-9	hSpCas9	negative selection	8145005
35337850	35337873	19	-	27260156	PANC1	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.27696888557432997	[841]	[468,766,627,557]	-4	hSpCas9	negative selection	8201977
35332903	35332926	19	+	27260156	PANC1	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.19832465213422212	[1078]	[857,1350,1067,1027]	3	hSpCas9	negative selection	8201978
35332539	35332562	19	+	27260156	PANC1	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.8168615898016266	[278]	[307,697,491,268]	9	hSpCas9	negative selection	8201979
35336222	35336245	19	-	27260156	PANC1	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	0.3954522793797346	[79]	[73,107,18,151]	6	hSpCas9	negative selection	8266254
35337918	35337941	19	+	27260156	PANC1	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.0024839826966080447	[340]	[392,368,147,273]	0	hSpCas9	negative selection	8266255
35338183	35338206	19	-	27260156	PANC1	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.5251454099359458	[367]	[164,183,198,305]	-7	hSpCas9	negative selection	8266256
35337850	35337873	19	-	27260156	PANC0813	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.17823787720064976	[841]	[896,1133,769,704]	-3	hSpCas9	negative selection	8323228
35332903	35332926	19	+	27260156	PANC0813	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.5133544691424474	[1078]	[1890,2009,1692,1654]	7	hSpCas9	negative selection	8323229
35332539	35332562	19	+	27260156	PANC0813	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.2745267917215236	[278]	[461,271,315,532]	4	hSpCas9	negative selection	8323230
35336222	35336245	19	-	27260156	PANC0813	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.6598172758840835	[79]	[126,8,64,43]	-7	hSpCas9	negative selection	8387505
35337918	35337941	19	+	27260156	PANC0813	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.0871070093983029	[340]	[369,439,409,291]	-1	hSpCas9	negative selection	8387506
35338183	35338206	19	-	27260156	PANC0813	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.28827675499749755	[367]	[564,254,355,263]	-4	hSpCas9	negative selection	8387507
35337850	35337873	19	-	27260156	RDES	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.20807521923600036	[841]	[641,692,1052,1035]	-4	hSpCas9	negative selection	8444479
35332903	35332926	19	+	27260156	RDES	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.33076363006893117	[1078]	[1286,1407,1698,1937]	5	hSpCas9	negative selection	8444480
35332539	35332562	19	+	27260156	RDES	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.3261010691662095	[278]	[416,233,478,495]	5	hSpCas9	negative selection	8444481
35336222	35336245	19	-	27260156	RDES	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.4118870165820887	[79]	[54,83,52,85]	-6	hSpCas9	negative selection	8508756
35337918	35337941	19	+	27260156	RDES	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.2912911504797698	[340]	[270,299,383,333]	-5	hSpCas9	negative selection	8508757
35338183	35338206	19	-	27260156	RDES	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.8099604731475971	[367]	[195,189,242,362]	-8	hSpCas9	negative selection	8508758
35337850	35337873	19	-	27260156	PC3	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.300460502266797	[841]	[474,420,1216,863]	-6	hSpCas9	negative selection	8565730
35332903	35332926	19	+	27260156	PC3	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.09900757212448874	[1078]	[915,986,1875,1081]	2	hSpCas9	negative selection	8565731
35332539	35332562	19	+	27260156	PC3	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.7550717404435886	[278]	[259,512,921,403]	9	hSpCas9	negative selection	8565732
35336222	35336245	19	-	27260156	PC3	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.35266394365304654	[79]	[48,34,128,62]	-7	hSpCas9	negative selection	8630007
35337918	35337941	19	+	27260156	PC3	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.2167671515231905	[340]	[188,439,742,400]	5	hSpCas9	negative selection	8630008
35338183	35338206	19	-	27260156	PC3	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.2821572321683315	[367]	[316,158,534,238]	-6	hSpCas9	negative selection	8630009
35337850	35337873	19	-	27260156	PATU8988T	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.61474266397467	[841]	[606,463,527,518]	-7	hSpCas9	negative selection	8686981
35332903	35332926	19	+	27260156	PATU8988T	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.2407218998648939	[1078]	[1341,1348,1111,1128]	4	hSpCas9	negative selection	8686982
35332539	35332562	19	+	27260156	PATU8988T	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.04644249794675248	[278]	[251,337,246,282]	0	hSpCas9	negative selection	8686983
35336222	35336245	19	-	27260156	PATU8988T	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.1693085502099998	[79]	[142,24,37,64]	-3	hSpCas9	negative selection	8751258
35337918	35337941	19	+	27260156	PATU8988T	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.2854774840499012	[340]	[256,387,125,327]	-5	hSpCas9	negative selection	8751259
35338183	35338206	19	-	27260156	PATU8988T	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.6860188344743787	[367]	[221,188,186,288]	-8	hSpCas9	negative selection	8751260
35337850	35337873	19	-	27260156	T47D	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.23304082003007687	[841]	[884,706,963,789]	-5	hSpCas9	negative selection	8808232
35332903	35332926	19	+	27260156	T47D	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.21961379380878054	[1078]	[1645,1276,1504,1441]	5	hSpCas9	negative selection	8808233
35332539	35332562	19	+	27260156	T47D	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.4219731001072203	[278]	[373,407,492,468]	8	hSpCas9	negative selection	8808234
35336222	35336245	19	-	27260156	T47D	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.3556026494713227	[79]	[56,60,97,75]	-6	hSpCas9	negative selection	8872509
35337918	35337941	19	+	27260156	T47D	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.05899732478587155	[340]	[499,329,394,438]	1	hSpCas9	negative selection	8872510
35338183	35338206	19	-	27260156	T47D	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.5378076668961687	[367]	[304,323,260,288]	-8	hSpCas9	negative selection	8872511
35337850	35337873	19	-	27260156	SU8686	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.26640787492491536	[841]	[583,694,674,854]	-4	hSpCas9	negative selection	8929483
35332903	35332926	19	+	27260156	SU8686	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.12476439078894219	[1078]	[1063,1043,1195,1422]	2	hSpCas9	negative selection	8929484
35332539	35332562	19	+	27260156	SU8686	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	-0.176872247626083	[278]	[184,262,181,369]	-3	hSpCas9	negative selection	8929485
35336222	35336245	19	-	27260156	SU8686	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-1.0472533245941933	[79]	[27,30,51,45]	-8	hSpCas9	negative selection	8993760
35337918	35337941	19	+	27260156	SU8686	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.5573762251644059	[340]	[264,110,246,320]	-7	hSpCas9	negative selection	8993761
35338183	35338206	19	-	27260156	SU8686	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.8208398969568005	[367]	[135,171,260,281]	-8	hSpCas9	negative selection	8993762
35337850	35337873	19	-	27260156	SKES1	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.4135381737504454	[841]	[525,582,735,646]	-7	hSpCas9	negative selection	9050734
35332903	35332926	19	+	27260156	SKES1	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.12885632792138102	[1078]	[1069,1394,1149,1100]	3	hSpCas9	negative selection	9050735
35332539	35332562	19	+	27260156	SKES1	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.21449801559643766	[278]	[402,325,313,263]	4	hSpCas9	negative selection	9050736
35336222	35336245	19	-	27260156	SKES1	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.009607434531162973	[79]	[68,48,105,85]	0	hSpCas9	negative selection	9115011
35337918	35337941	19	+	27260156	SKES1	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.028972029067376948	[340]	[367,361,346,315]	0	hSpCas9	negative selection	9115012
35338183	35338206	19	-	27260156	SKES1	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.45815300593358305	[367]	[255,376,252,199]	-7	hSpCas9	negative selection	9115013
35337850	35337873	19	-	27260156	TOV112D	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.20039489012439005	[841]	[866,965,549,622]	-4	hSpCas9	negative selection	9171985
35332903	35332926	19	+	27260156	TOV112D	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.3047882305693552	[1078]	[1299,1848,979,1331]	6	hSpCas9	negative selection	9171986
35332539	35332562	19	+	27260156	TOV112D	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.30545757374211296	[278]	[490,269,323,290]	6	hSpCas9	negative selection	9171987
35336222	35336245	19	-	27260156	TOV112D	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.5457288479721165	[79]	[33,33,32,109]	-8	hSpCas9	negative selection	9236262
35337918	35337941	19	+	27260156	TOV112D	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	0.1903938265011384	[340]	[305,526,255,492]	3	hSpCas9	negative selection	9236263
35338183	35338206	19	-	27260156	TOV112D	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.757100536974763	[367]	[202,341,167,188]	-9	hSpCas9	negative selection	9236264
35337850	35337873	19	-	27260156	TC71	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.27401351606888724	[841]	[843,750,613,780]	-6	hSpCas9	negative selection	9293236
35332903	35332926	19	+	27260156	TC71	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.1456509010320206	[1078]	[1222,1225,1362,1305]	3	hSpCas9	negative selection	9293237
35332539	35332562	19	+	27260156	TC71	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.6502649419353391	[278]	[512,451,386,530]	9	hSpCas9	negative selection	9293238
35336222	35336245	19	-	27260156	TC71	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.05804556629493396	[79]	[58,66,117,84]	-1	hSpCas9	negative selection	9357513
35337918	35337941	19	+	27260156	TC71	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.07775705842511232	[340]	[336,280,400,365]	-2	hSpCas9	negative selection	9357514
35338183	35338206	19	-	27260156	TC71	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.0847863877280336	[367]	[395,344,395,347]	-2	hSpCas9	negative selection	9357515
35337850	35337873	19	-	27260156	TC32	viability	CAGGATACCGTCGTGTACTCCGG	CD22	ENSG00000012124	-0.22896515224741787	[841]	[600,505,990,691]	-4	hSpCas9	negative selection	9414487
35332903	35332926	19	+	27260156	TC32	viability	CGAATACACCTCAATGTCTCTGG	CD22	ENSG00000012124	0.43500728562559376	[1078]	[1141,1169,1798,1473]	7	hSpCas9	negative selection	9414488
35332539	35332562	19	+	27260156	TC32	viability	GTGGTGAGTTCTAGAATACTTGG	CD22	ENSG00000012124	0.3229993429404632	[278]	[337,207,391,414]	5	hSpCas9	negative selection	9414489
35336222	35336245	19	-	27260156	TC32	viability	GGAGAACTTGAGCTCGCTCCGGG	CD22	ENSG00000012124	-0.40761987690822243	[79]	[47,26,112,57]	-6	hSpCas9	negative selection	9478764
35337918	35337941	19	+	27260156	TC32	viability	AAACCTGCGCGAAGTGACCAAGG	CD22	ENSG00000012124	-0.26826183600219206	[340]	[212,162,387,357]	-5	hSpCas9	negative selection	9478765
35338183	35338206	19	-	27260156	TC32	viability	TGAGTGGAGGATCTGAACCGTGG	CD22	ENSG00000012124	-0.6370598831576813	[367]	[182,188,276,255]	-8	hSpCas9	negative selection	9478766
35332070	35332093	19	-	27869803	HPAFII	viability after 27 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.40084251365395407	[446]	[456,187,NaN]	3	hSpCas9	negative selection	9567185
35332834	35332857	19	-	27869803	HPAFII	viability after 27 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.7513962453986941	[231]	[30,106,NaN]	-5	hSpCas9	negative selection	9567186
35336102	35336125	19	-	27869803	HPAFII	viability after 27 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.9535756629086478	[209]	[341,106,NaN]	7	hSpCas9	negative selection	9567187
35337966	35337989	19	+	27869803	HPAFII	viability after 27 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	1.3075326119886483	[69]	[185,11,NaN]	9	hSpCas9	negative selection	9567188
35338382	35338405	19	+	27869803	HPAFII	viability after 27 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-2.0540308312017563	[162]	[18,21,NaN]	-8	hSpCas9	negative selection	9567189
35341117	35341140	19	-	27869803	HPAFII	viability after 27 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.3201476728508524	[149]	[92,102,NaN]	2	hSpCas9	negative selection	9567190
35332070	35332093	19	-	27869803	HPAFII	viability after 15 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.27971013587286764	[446]	[798,448,NaN]	3	hSpCas9	negative selection	9649634
35332834	35332857	19	-	27869803	HPAFII	viability after 15 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	0.33077282475145253	[231]	[365,280,NaN]	4	hSpCas9	negative selection	9649635
35336102	35336125	19	-	27869803	HPAFII	viability after 15 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	1.014809950010176	[209]	[743,276,NaN]	9	hSpCas9	negative selection	9649636
35337966	35337989	19	+	27869803	HPAFII	viability after 15 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	0.669485324445722	[69]	[176,83,NaN]	7	hSpCas9	negative selection	9649637
35338382	35338405	19	+	27869803	HPAFII	viability after 15 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	0.22752349733254917	[162]	[267,165,NaN]	2	hSpCas9	negative selection	9649638
35341117	35341140	19	-	27869803	HPAFII	viability after 15 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.7326778727972084	[149]	[286,255,NaN]	7	hSpCas9	negative selection	9649639
35332070	35332093	19	-	27869803	ASPC1	viability after 36 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.8018238728617334	[1157]	[1606,277,402]	7	hSpCas9	negative selection	9732083
35332834	35332857	19	-	27869803	ASPC1	viability after 36 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.15497734386401585	[925]	[428,317,167]	-2	hSpCas9	negative selection	9732084
35336102	35336125	19	-	27869803	ASPC1	viability after 36 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	1.1219124885366205	[832]	[890,870,255]	9	hSpCas9	negative selection	9732085
35337966	35337989	19	+	27869803	ASPC1	viability after 36 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	-1.1269920970517344	[156]	[25,13,32]	-8	hSpCas9	negative selection	9732086
35338382	35338405	19	+	27869803	ASPC1	viability after 36 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-0.6302648056061362	[376]	[72,120,63]	-6	hSpCas9	negative selection	9732087
35341117	35341140	19	-	27869803	ASPC1	viability after 36 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.3342373253576611	[469]	[97,61,395]	3	hSpCas9	negative selection	9732088
35332070	35332093	19	-	27869803	PATU8988S	viability after 35 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.12437439350346358	[1080]	[505,442,NaN]	1	hSpCas9	negative selection	9814532
35332834	35332857	19	-	27869803	PATU8988S	viability after 35 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.10588587374065411	[720]	[415,122,NaN]	-1	hSpCas9	negative selection	9814533
35336102	35336125	19	-	27869803	PATU8988S	viability after 35 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.6223183994285402	[571]	[408,299,NaN]	6	hSpCas9	negative selection	9814534
35337966	35337989	19	+	27869803	PATU8988S	viability after 35 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	-0.772510906678856	[190]	[58,30,NaN]	-6	hSpCas9	negative selection	9814535
35338382	35338405	19	+	27869803	PATU8988S	viability after 35 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-0.7377460990133986	[332]	[47,112,NaN]	-6	hSpCas9	negative selection	9814536
35341117	35341140	19	-	27869803	PATU8988S	viability after 35 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	-0.9949306166134704	[504]	[124,78,NaN]	-7	hSpCas9	negative selection	9814537
35332070	35332093	19	-	27869803	PATU8988S	viability after 31 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.13339015431727286	[1080]	[452,497,NaN]	1	hSpCas9	negative selection	9896981
35332834	35332857	19	-	27869803	PATU8988S	viability after 31 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.5733218353841174	[720]	[267,97,NaN]	-6	hSpCas9	negative selection	9896982
35336102	35336125	19	-	27869803	PATU8988S	viability after 31 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.38007760214445097	[571]	[236,372,NaN]	4	hSpCas9	negative selection	9896983
35337966	35337989	19	+	27869803	PATU8988S	viability after 31 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	0.00824251635674389	[190]	[58,98,NaN]	0	hSpCas9	negative selection	9896984
35338382	35338405	19	+	27869803	PATU8988S	viability after 31 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-0.4295812466744684	[332]	[36,176,NaN]	-5	hSpCas9	negative selection	9896985
35341117	35341140	19	-	27869803	PATU8988S	viability after 31 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	-0.05404624307767325	[504]	[200,184,NaN]	0	hSpCas9	negative selection	9896986
35332070	35332093	19	-	27869803	HPAFII	viability after 35 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	0.2910819823958729	[446]	[393,144,NaN]	1	hSpCas9	negative selection	9979430
35332834	35332857	19	-	27869803	HPAFII	viability after 35 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.5241239072297792	[231]	[12,158,NaN]	-3	hSpCas9	negative selection	9979431
35336102	35336125	19	-	27869803	HPAFII	viability after 35 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	1.0087769931876587	[209]	[291,125,NaN]	6	hSpCas9	negative selection	9979432
35337966	35337989	19	+	27869803	HPAFII	viability after 35 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	0.965373816488425	[69]	[103,29,NaN]	6	hSpCas9	negative selection	9979433
35338382	35338405	19	+	27869803	HPAFII	viability after 35 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-1.8963625419180894	[162]	[0,45,NaN]	-7	hSpCas9	negative selection	9979434
35341117	35341140	19	-	27869803	HPAFII	viability after 35 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.3612141450280221	[149]	[121,69,NaN]	2	hSpCas9	negative selection	9979435
35332070	35332093	19	-	27869803	HPAFII	viability after 31 days	CCAGGCCACAGTCCTTACCCAGG	CD22	ENSG00000012124	-0.007368271727792752	[446]	[351,137,NaN]	0	hSpCas9	negative selection	10061879
35332834	35332857	19	-	27869803	HPAFII	viability after 31 days	CCACTGTCATTGAGGTGCACCGG	CD22	ENSG00000012124	-0.030660531460895896	[231]	[14,249,NaN]	0	hSpCas9	negative selection	10061880
35336102	35336125	19	-	27869803	HPAFII	viability after 31 days	GCAGGAGAAATTCAGCAAGCAGG	CD22	ENSG00000012124	0.8001130374840546	[209]	[276,126,NaN]	6	hSpCas9	negative selection	10061881
35337966	35337989	19	+	27869803	HPAFII	viability after 31 days	GGTCTCCAATGACGTGGGCCCGG	CD22	ENSG00000012124	1.5196087190469272	[69]	[137,84,NaN]	9	hSpCas9	negative selection	10061882
35338382	35338405	19	+	27869803	HPAFII	viability after 31 days	CATTCTTGGTACTGGACAGAGGG	CD22	ENSG00000012124	-1.8070120383293813	[162]	[6,46,NaN]	-7	hSpCas9	negative selection	10061883
35341117	35341140	19	-	27869803	HPAFII	viability after 31 days	CACTGGACATTCAGGGCGACAGG	CD22	ENSG00000012124	0.6916364416840346	[149]	[190,75,NaN]	5	hSpCas9	negative selection	10061884
35336047	35336070	19	-	28162770	P31FUJ	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-5.756364160471391	[45]	[0]	-9	hSpCas9	negative selection	10129192
35332625	35332648	19	-	28162770	P31FUJ	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-0.7641836649306907	[184]	[127]	-5	hSpCas9	negative selection	10129193
35336129	35336152	19	+	28162770	P31FUJ	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-0.025644296773090824	[271]	[313]	0	hSpCas9	negative selection	10129194
35336307	35336330	19	-	28162770	P31FUJ	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.539338248884759	[302]	[244]	-4	hSpCas9	negative selection	10129195
35341024	35341047	19	-	28162770	P31FUJ	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.4076554088984814	[67]	[105]	4	hSpCas9	negative selection	10129196
35341112	35341135	19	-	28162770	P31FUJ	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.5516741056020588	[226]	[390]	6	hSpCas9	negative selection	10129197
35341789	35341812	19	-	28162770	P31FUJ	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-3.2328022044143783	[39]	[4]	-9	hSpCas9	negative selection	10129198
35341859	35341882	19	+	28162770	P31FUJ	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	0.8615251781337745	[147]	[315]	8	hSpCas9	negative selection	10129199
35344904	35344927	19	+	28162770	P31FUJ	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	0.29813441462426693	[262]	[379]	3	hSpCas9	negative selection	10129200
35345056	35345079	19	+	28162770	P31FUJ	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.5299139791305318	[316]	[257]	-4	hSpCas9	negative selection	10129201
35336047	35336070	19	-	28162770	TF1	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10298558
35332625	35332648	19	-	28162770	TF1	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10298559
35336129	35336152	19	+	28162770	TF1	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10298560
35336307	35336330	19	-	28162770	TF1	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10298561
35341024	35341047	19	-	28162770	TF1	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10298562
35341112	35341135	19	-	28162770	TF1	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	NaN	[NaN]	[134]	1	hSpCas9	negative selection	10298563
35341789	35341812	19	-	28162770	TF1	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10298564
35341859	35341882	19	+	28162770	TF1	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	NaN	[NaN]	[18]	1	hSpCas9	negative selection	10298565
35344904	35344927	19	+	28162770	TF1	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10298566
35345056	35345079	19	+	28162770	TF1	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10298567
35336047	35336070	19	-	28162770	SKM1	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-3.880895387075574	[24]	[2]	-9	hSpCas9	negative selection	10467924
35332625	35332648	19	-	28162770	SKM1	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-0.8220016980220056	[32]	[32]	-6	hSpCas9	negative selection	10467925
35336129	35336152	19	+	28162770	SKM1	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.9829264866410585	[84]	[296]	8	hSpCas9	negative selection	10467926
35336307	35336330	19	-	28162770	SKM1	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.37168872399563113	[100]	[137]	-3	hSpCas9	negative selection	10467927
35341024	35341047	19	-	28162770	SKM1	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.499926396865357	[23]	[59]	5	hSpCas9	negative selection	10467928
35341112	35341135	19	-	28162770	SKM1	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.152311658314345	[84]	[166]	1	hSpCas9	negative selection	10467929
35341789	35341812	19	-	28162770	SKM1	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	0.5930358012568382	[8]	[23]	6	hSpCas9	negative selection	10467930
35341859	35341882	19	+	28162770	SKM1	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	0.8154282225932861	[35]	[111]	7	hSpCas9	negative selection	10467931
35344904	35344927	19	+	28162770	SKM1	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	-0.13168619715462077	[43]	[70]	-1	hSpCas9	negative selection	10467932
35345056	35345079	19	+	28162770	SKM1	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.23703919730084946	[57]	[86]	-2	hSpCas9	negative selection	10467933
35336047	35336070	19	-	28162770	SKM1	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-3.880895387075574	[24]	[2]	-9	hSpCas9	negative selection	10637290
35332625	35332648	19	-	28162770	SKM1	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-0.8220016980220056	[32]	[32]	-6	hSpCas9	negative selection	10637291
35336129	35336152	19	+	28162770	SKM1	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.9829264866410585	[84]	[296]	8	hSpCas9	negative selection	10637292
35336307	35336330	19	-	28162770	SKM1	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.37168872399563113	[100]	[137]	-3	hSpCas9	negative selection	10637293
35341024	35341047	19	-	28162770	SKM1	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.499926396865357	[23]	[59]	5	hSpCas9	negative selection	10637294
35341112	35341135	19	-	28162770	SKM1	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.152311658314345	[84]	[166]	1	hSpCas9	negative selection	10637295
35341789	35341812	19	-	28162770	SKM1	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	0.5930358012568382	[8]	[23]	6	hSpCas9	negative selection	10637296
35341859	35341882	19	+	28162770	SKM1	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	0.8154282225932861	[35]	[111]	7	hSpCas9	negative selection	10637297
35344904	35344927	19	+	28162770	SKM1	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	-0.13168619715462077	[43]	[70]	-1	hSpCas9	negative selection	10637298
35345056	35345079	19	+	28162770	SKM1	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.23703919730084946	[57]	[86]	-2	hSpCas9	negative selection	10637299
35336047	35336070	19	-	28162770	PL21	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-4.00931375113963	[36]	[0]	-9	hSpCas9	negative selection	10806656
35332625	35332648	19	-	28162770	PL21	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	0.11133034753146409	[133]	[62]	1	hSpCas9	negative selection	10806657
35336129	35336152	19	+	28162770	PL21	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.8274369523688319	[346]	[267]	7	hSpCas9	negative selection	10806658
35336307	35336330	19	-	28162770	PL21	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.5127910478349689	[376]	[114]	-4	hSpCas9	negative selection	10806659
35341024	35341047	19	-	28162770	PL21	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.282601774681293	[67]	[35]	2	hSpCas9	negative selection	10806660
35341112	35341135	19	-	28162770	PL21	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	1.2098875910408822	[294]	[296]	8	hSpCas9	negative selection	10806661
35341789	35341812	19	-	28162770	PL21	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-0.21489788478952399	[31]	[11]	-1	hSpCas9	negative selection	10806662
35341859	35341882	19	+	28162770	PL21	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	1.4631740203231138	[84]	[101]	9	hSpCas9	negative selection	10806663
35344904	35344927	19	+	28162770	PL21	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	1.697639273960137	[152]	[215]	9	hSpCas9	negative selection	10806664
35345056	35345079	19	+	28162770	PL21	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.030744267740767328	[283]	[120]	0	hSpCas9	negative selection	10806665
35336047	35336070	19	-	28162770	P31FUJ	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-5.756364160471391	[45]	[0]	-9	hSpCas9	negative selection	10976022
35332625	35332648	19	-	28162770	P31FUJ	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-0.7641836649306907	[184]	[127]	-5	hSpCas9	negative selection	10976023
35336129	35336152	19	+	28162770	P31FUJ	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-0.025644296773090824	[271]	[313]	0	hSpCas9	negative selection	10976024
35336307	35336330	19	-	28162770	P31FUJ	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.539338248884759	[302]	[244]	-4	hSpCas9	negative selection	10976025
35341024	35341047	19	-	28162770	P31FUJ	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.4076554088984814	[67]	[105]	4	hSpCas9	negative selection	10976026
35341112	35341135	19	-	28162770	P31FUJ	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.5516741056020588	[226]	[390]	6	hSpCas9	negative selection	10976027
35341789	35341812	19	-	28162770	P31FUJ	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-3.2328022044143783	[39]	[4]	-9	hSpCas9	negative selection	10976028
35341859	35341882	19	+	28162770	P31FUJ	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	0.8615251781337745	[147]	[315]	8	hSpCas9	negative selection	10976029
35344904	35344927	19	+	28162770	P31FUJ	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	0.29813441462426693	[262]	[379]	3	hSpCas9	negative selection	10976030
35345056	35345079	19	+	28162770	P31FUJ	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.5299139791305318	[316]	[257]	-4	hSpCas9	negative selection	10976031
35336047	35336070	19	-	28162770	OCIAML5	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-5.852066570863997	[31]	[0]	-9	hSpCas9	negative selection	11145388
35332625	35332648	19	-	28162770	OCIAML5	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-2.079872488386809	[88]	[37]	-8	hSpCas9	negative selection	11145389
35336129	35336152	19	+	28162770	OCIAML5	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.10532725775814311	[188]	[366]	0	hSpCas9	negative selection	11145390
35336307	35336330	19	-	28162770	OCIAML5	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.019460971690987594	[177]	[316]	0	hSpCas9	negative selection	11145391
35341024	35341047	19	-	28162770	OCIAML5	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.1607574694935866	[55]	[112]	1	hSpCas9	negative selection	11145392
35341112	35341135	19	-	28162770	OCIAML5	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	1.21165902674639	[154]	[647]	8	hSpCas9	negative selection	11145393
35341789	35341812	19	-	28162770	OCIAML5	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-3.6069540730274654	[26]	[3]	-9	hSpCas9	negative selection	11145394
35341859	35341882	19	+	28162770	OCIAML5	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	0.46986152402336534	[77]	[194]	4	hSpCas9	negative selection	11145395
35344904	35344927	19	+	28162770	OCIAML5	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	-0.12929485828054524	[142]	[235]	-1	hSpCas9	negative selection	11145396
35345056	35345079	19	+	28162770	OCIAML5	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.7062157044005422	[187]	[207]	-5	hSpCas9	negative selection	11145397
35336047	35336070	19	-	28162770	EOL1	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-3.310668690123497	[112]	[5]	-9	hSpCas9	negative selection	11314754
35332625	35332648	19	-	28162770	EOL1	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	0.3395852708493782	[155]	[103]	3	hSpCas9	negative selection	11314755
35336129	35336152	19	+	28162770	EOL1	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-0.4223747027836973	[523]	[205]	-3	hSpCas9	negative selection	11314756
35336307	35336330	19	-	28162770	EOL1	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.9384713256020685	[752]	[206]	-6	hSpCas9	negative selection	11314757
35341024	35341047	19	-	28162770	EOL1	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	-0.43121391839270296	[150]	[58]	-3	hSpCas9	negative selection	11314758
35341112	35341135	19	-	28162770	EOL1	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.49219568698952154	[474]	[351]	4	hSpCas9	negative selection	11314759
35341789	35341812	19	-	28162770	EOL1	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-1.5017169831315638	[42]	[7]	-7	hSpCas9	negative selection	11314760
35341859	35341882	19	+	28162770	EOL1	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	0.532780051614538	[163]	[124]	5	hSpCas9	negative selection	11314761
35344904	35344927	19	+	28162770	EOL1	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	0.14961432720530787	[230]	[134]	1	hSpCas9	negative selection	11314762
35345056	35345079	19	+	28162770	EOL1	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.6604147291506216	[266]	[88]	-5	hSpCas9	negative selection	11314763
35336047	35336070	19	-	28162770	MOLM13	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-0.05211767733580763	[75]	[52]	0	hSpCas9	negative selection	11484120
35332625	35332648	19	-	28162770	MOLM13	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-0.8136809757266424	[140]	[57]	-4	hSpCas9	negative selection	11484121
35336129	35336152	19	+	28162770	MOLM13	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.2815784058633837	[486]	[427]	2	hSpCas9	negative selection	11484122
35336307	35336330	19	-	28162770	MOLM13	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.16728456513034495	[496]	[319]	-1	hSpCas9	negative selection	11484123
35341024	35341047	19	-	28162770	MOLM13	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	1.3634201149885494	[135]	[252]	9	hSpCas9	negative selection	11484124
35341112	35341135	19	-	28162770	MOLM13	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	1.258693127338335	[262]	[454]	8	hSpCas9	negative selection	11484125
35341789	35341812	19	-	28162770	MOLM13	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-4.576504737813875	[32]	[0]	-9	hSpCas9	negative selection	11484126
35341859	35341882	19	+	28162770	MOLM13	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	0.5210007180041413	[159]	[165]	4	hSpCas9	negative selection	11484127
35344904	35344927	19	+	28162770	MOLM13	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	-0.8021997818231654	[245]	[101]	-4	hSpCas9	negative selection	11484128
35345056	35345079	19	+	28162770	MOLM13	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.7319251918166594	[316]	[137]	-4	hSpCas9	negative selection	11484129
35336047	35336070	19	-	28162770	HEL	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-1.8897562488266635	[80]	[13]	-7	hSpCas9	negative selection	11653486
35332625	35332648	19	-	28162770	HEL	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-1.357261167999643	[131]	[32]	-7	hSpCas9	negative selection	11653487
35336129	35336152	19	+	28162770	HEL	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-0.5728962231607824	[496]	[213]	-4	hSpCas9	negative selection	11653488
35336307	35336330	19	-	28162770	HEL	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	0.012547077286202857	[485]	[313]	0	hSpCas9	negative selection	11653489
35341024	35341047	19	-	28162770	HEL	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.13102531330983935	[143]	[100]	1	hSpCas9	negative selection	11653490
35341112	35341135	19	-	28162770	HEL	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.3894975186603034	[322]	[270]	3	hSpCas9	negative selection	11653491
35341789	35341812	19	-	28162770	HEL	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-4.6791892628870055	[39]	[0]	-9	hSpCas9	negative selection	11653492
35341859	35341882	19	+	28162770	HEL	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	-0.4889668472114651	[148]	[67]	-3	hSpCas9	negative selection	11653493
35344904	35344927	19	+	28162770	HEL	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	0.29970510410134316	[240]	[189]	2	hSpCas9	negative selection	11653494
35345056	35345079	19	+	28162770	HEL	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.7089366062810575	[244]	[95]	-4	hSpCas9	negative selection	11653495
35336047	35336070	19	-	28162770	MV411	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-0.3262976945151268	[63]	[42]	-2	hSpCas9	negative selection	11822852
35332625	35332648	19	-	28162770	MV411	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-1.4046391457969176	[131]	[41]	-7	hSpCas9	negative selection	11822853
35336129	35336152	19	+	28162770	MV411	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	-0.379519038603008	[243]	[157]	-3	hSpCas9	negative selection	11822854
35336307	35336330	19	-	28162770	MV411	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-1.2700970224180903	[417]	[145]	-7	hSpCas9	negative selection	11822855
35341024	35341047	19	-	28162770	MV411	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.03419351166051254	[130]	[112]	0	hSpCas9	negative selection	11822856
35341112	35341135	19	-	28162770	MV411	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.3532826384126989	[288]	[310]	3	hSpCas9	negative selection	11822857
35341789	35341812	19	-	28162770	MV411	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	1.3849410745327102	[9]	[21]	9	hSpCas9	negative selection	11822858
35341859	35341882	19	+	28162770	MV411	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	-1.0116496705343556	[145]	[60]	-6	hSpCas9	negative selection	11822859
35344904	35344927	19	+	28162770	MV411	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	0.3128135596347993	[150]	[157]	2	hSpCas9	negative selection	11822860
35345056	35345079	19	+	28162770	MV411	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.4559984198182364	[240]	[147]	-3	hSpCas9	negative selection	11822861
35336047	35336070	19	-	28162770	MONOMAC1	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-1.494717395700239	[58]	[23]	-8	hSpCas9	negative selection	11992218
35332625	35332648	19	-	28162770	MONOMAC1	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-0.8712666858777973	[74]	[46]	-6	hSpCas9	negative selection	11992219
35336129	35336152	19	+	28162770	MONOMAC1	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.8878520505269591	[197]	[419]	7	hSpCas9	negative selection	11992220
35336307	35336330	19	-	28162770	MONOMAC1	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	0.02628784897226888	[220]	[257]	0	hSpCas9	negative selection	11992221
35341024	35341047	19	-	28162770	MONOMAC1	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.2920012336630671	[56]	[79]	3	hSpCas9	negative selection	11992222
35341112	35341135	19	-	28162770	MONOMAC1	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.4030325460518107	[189]	[287]	4	hSpCas9	negative selection	11992223
35341789	35341812	19	-	28162770	MONOMAC1	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-2.4449643605031395	[18]	[3]	-9	hSpCas9	negative selection	11992224
35341859	35341882	19	+	28162770	MONOMAC1	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	-0.13563630239541058	[68]	[71]	-1	hSpCas9	negative selection	11992225
35344904	35344927	19	+	28162770	MONOMAC1	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	-0.6502094752251686	[114]	[83]	-5	hSpCas9	negative selection	11992226
35345056	35345079	19	+	28162770	MONOMAC1	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	0.25362456195001154	[149]	[204]	2	hSpCas9	negative selection	11992227
35336047	35336070	19	-	28162770	OCIAML2	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-3.0921182019884315	[19]	[12]	-9	hSpCas9	negative selection	12161584
35332625	35332648	19	-	28162770	OCIAML2	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	-2.3331263014922263	[9]	[10]	-8	hSpCas9	negative selection	12161585
35336129	35336152	19	+	28162770	OCIAML2	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.682844655419557	[48]	[435]	6	hSpCas9	negative selection	12161586
35336307	35336330	19	-	28162770	OCIAML2	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	-0.09639285708875733	[64]	[336]	-1	hSpCas9	negative selection	12161587
35341024	35341047	19	-	28162770	OCIAML2	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.5852234094913562	[18]	[157]	5	hSpCas9	negative selection	12161588
35341112	35341135	19	-	28162770	OCIAML2	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	0.5470000687796299	[60]	[493]	5	hSpCas9	negative selection	12161589
35341789	35341812	19	-	28162770	OCIAML2	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-2.4706298252421615	[3]	[3]	-8	hSpCas9	negative selection	12161590
35341859	35341882	19	+	28162770	OCIAML2	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	-0.7436483196485772	[28]	[95]	-5	hSpCas9	negative selection	12161591
35344904	35344927	19	+	28162770	OCIAML2	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	0.1616383902573516	[19]	[123]	1	hSpCas9	negative selection	12161592
35345056	35345079	19	+	28162770	OCIAML2	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	-0.16743829293638465	[30]	[152]	-1	hSpCas9	negative selection	12161593
35336047	35336070	19	-	28162770	OCIAML3	viability	GGAGGGAGCTGGATATGAGGTGG	CD22	ENSG00000012124	-1.857042046157957	[17]	[14]	-8	hSpCas9	negative selection	12330950
35332625	35332648	19	-	28162770	OCIAML3	viability	GGTGCAGGGGATCCAGACGCAGG	CD22	ENSG00000012124	0.12588444048310155	[33]	[111]	1	hSpCas9	negative selection	12330951
35336129	35336152	19	+	28162770	OCIAML3	viability	GGTATCCGATCCAATTGCAGTGG	CD22	ENSG00000012124	0.28961317596150826	[99]	[368]	2	hSpCas9	negative selection	12330952
35336307	35336330	19	-	28162770	OCIAML3	viability	GCTGCACCGTGTCATTGGAGAGG	CD22	ENSG00000012124	0.02179226431958603	[107]	[330]	0	hSpCas9	negative selection	12330953
35341024	35341047	19	-	28162770	OCIAML3	viability	ATCTTCAGCACCCCAAGCGATGG	CD22	ENSG00000012124	0.5503822690110117	[18]	[83]	5	hSpCas9	negative selection	12330954
35341112	35341135	19	-	28162770	OCIAML3	viability	GACATTCAGGGCGACAGGGGAGG	CD22	ENSG00000012124	-0.2294352080283072	[79]	[205]	-2	hSpCas9	negative selection	12330955
35341789	35341812	19	-	28162770	OCIAML3	viability	GTAGTGGGAGACGGGAGGGTTGG	CD22	ENSG00000012124	-0.34608012688057777	[7]	[18]	-3	hSpCas9	negative selection	12330956
35341859	35341882	19	+	28162770	OCIAML3	viability	GCTGAGATTGGAGCCGGTGAAGG	CD22	ENSG00000012124	0.6023895724793401	[23]	[109]	5	hSpCas9	negative selection	12330957
35344904	35344927	19	+	28162770	OCIAML3	viability	GTGGGCTCAAGCTCCAGCGACGG	CD22	ENSG00000012124	-0.009045139603006954	[52]	[158]	0	hSpCas9	negative selection	12330958
35345056	35345079	19	+	28162770	OCIAML3	viability	AGAGGACACAGAGCCAGCAGGGG	CD22	ENSG00000012124	0.37509835173005324	[58]	[230]	3	hSpCas9	negative selection	12330959