Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:29126
• Symbol:CD274
• Description:CD274 molecule

DataSource: http://genomecrispr.dkfz.de/#!/results/CD274

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
5465566	5465589	9	-	26472758	Jiyoye	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.5595611019365607	[376]	[418]	4	hSpCas9	negative selection	27274
5463085	5463108	9	-	26472758	Jiyoye	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	1.2436766492229938	[27]	[49]	7	hSpCas9	negative selection	27275
5462904	5462927	9	+	26472758	Jiyoye	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	0.13016803311947522	[331]	[273]	1	hSpCas9	negative selection	27276
5465549	5465572	9	+	26472758	Jiyoye	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	1.8161890931569473	[89]	[238]	8	hSpCas9	negative selection	27277
5462892	5462915	9	+	26472758	Jiyoye	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	4.070140394228302	[2]	[37]	9	hSpCas9	negative selection	27278
5462975	5462998	9	-	26472758	Jiyoye	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	0.22899566550174988	[240]	[212]	1	hSpCas9	negative selection	27279
5462947	5462970	9	+	26472758	Jiyoye	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	-0.9497591632094022	[145]	[56]	-6	hSpCas9	negative selection	27280
5463100	5463123	9	+	26472758	Jiyoye	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	-0.23668080826885138	[149]	[95]	-2	hSpCas9	negative selection	27281
5465504	5465527	9	-	26472758	Jiyoye	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	1.199662136508196	[208]	[361]	7	hSpCas9	negative selection	27282
5463020	5463043	9	-	26472758	Jiyoye	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	-0.29995898920922714	[350]	[214]	-2	hSpCas9	negative selection	27283
5465566	5465589	9	-	26472758	KBM7	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.8069548621158988	[1769,1479]	[1424,1246]	8	hSpCas9	negative selection	218392
5463085	5463108	9	-	26472758	KBM7	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.986089023976021	[285,321]	[366,213]	9	hSpCas9	negative selection	218393
5462904	5462927	9	+	26472758	KBM7	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	0.2505169012069812	[1215,978]	[664,560]	2	hSpCas9	negative selection	218394
5465549	5465572	9	+	26472758	KBM7	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	0.7730641310787144	[689,505]	[422,521]	8	hSpCas9	negative selection	218395
5462892	5462915	9	+	26472758	KBM7	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.13408699588517536	[293,110]	[181,26]	1	hSpCas9	negative selection	218396
5462975	5462998	9	-	26472758	KBM7	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	0.5949153376670824	[768,714]	[488,561]	6	hSpCas9	negative selection	218397
5462947	5462970	9	+	26472758	KBM7	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.4843334700598002	[481,375]	[317,245]	5	hSpCas9	negative selection	218398
5463100	5463123	9	+	26472758	KBM7	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	-0.053452736117635846	[735,542]	[235,331]	0	hSpCas9	negative selection	218399
5465504	5465527	9	-	26472758	KBM7	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.5410034680949247	[1585,1342]	[983,1010]	6	hSpCas9	negative selection	218400
5463020	5463043	9	-	26472758	KBM7	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.2627043910960303	[1084,1332]	[881,522]	2	hSpCas9	negative selection	218401
5465566	5465589	9	-	26472758	Raji	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.5464665086190945	[713]	[241]	5	hSpCas9	negative selection	409510
5463085	5463108	9	-	26472758	Raji	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.45394129676967665	[150]	[47]	4	hSpCas9	negative selection	409511
5462904	5462927	9	+	26472758	Raji	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	0.07787954106351669	[493]	[120]	0	hSpCas9	negative selection	409512
5465549	5465572	9	+	26472758	Raji	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	0.45370828456842915	[257]	[81]	4	hSpCas9	negative selection	409513
5462892	5462915	9	+	26472758	Raji	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	-0.5115262972708945	[85]	[13]	-4	hSpCas9	negative selection	409514
5462975	5462998	9	-	26472758	Raji	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	0.08299937674664037	[357]	[87]	0	hSpCas9	negative selection	409515
5462947	5462970	9	+	26472758	Raji	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.17347272583137213	[255]	[66]	1	hSpCas9	negative selection	409516
5463100	5463123	9	+	26472758	Raji	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.8658569470804364	[252]	[106]	7	hSpCas9	negative selection	409517
5465504	5465527	9	-	26472758	Raji	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.4026817903783475	[677]	[207]	4	hSpCas9	negative selection	409518
5463020	5463043	9	-	26472758	Raji	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.01661807145041716	[655]	[153]	0	hSpCas9	negative selection	409519
5465566	5465589	9	-	26472758	K562	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.6215596191867621	[1214]	[1577]	5	hSpCas9	negative selection	600628
5463085	5463108	9	-	26472758	K562	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	1.4690496211988942	[183]	[429]	9	hSpCas9	negative selection	600629
5462904	5462927	9	+	26472758	K562	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-1.369522840026475	[703]	[229]	-6	hSpCas9	negative selection	600630
5465549	5465572	9	+	26472758	K562	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	0.14631928623105156	[501]	[468]	1	hSpCas9	negative selection	600631
5462892	5462915	9	+	26472758	K562	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.4753026098965345	[120]	[141]	4	hSpCas9	negative selection	600632
5462975	5462998	9	-	26472758	K562	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	1.406936192812501	[498]	[1116]	9	hSpCas9	negative selection	600633
5462947	5462970	9	+	26472758	K562	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.8413538700536792	[399]	[604]	7	hSpCas9	negative selection	600634
5463100	5463123	9	+	26472758	K562	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.5052353082504222	[433]	[519]	4	hSpCas9	negative selection	600635
5465504	5465527	9	-	26472758	K562	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.2559041977644947	[1125]	[1134]	2	hSpCas9	negative selection	600636
5463020	5463043	9	-	26472758	K562	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.18435215909446856	[1127]	[1081]	1	hSpCas9	negative selection	600637
5457080	5457103	9	+	26627737	DLD1	viability	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	2.1344699253782373	[35]	[11,47,82]	9	hSpCas9	negative selection	843099
5465504	5465527	9	-	26627737	DLD1	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.22310895927137414	[337]	[179,189,18]	2	hSpCas9	negative selection	843100
5465566	5465589	9	-	26627737	DLD1	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.10216388446288338	[1409]	[393,371,456]	-1	hSpCas9	negative selection	843101
5457080	5457103	9	+	26627737	GBM cells	viability after 5 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-0.3542050620830255	[86]	[40,31]	-5	hSpCas9	negative selection	925414
5465504	5465527	9	-	26627737	GBM cells	viability after 5 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.5607451389911122	[200]	[129,187]	7	hSpCas9	negative selection	925415
5465566	5465589	9	-	26627737	GBM cells	viability after 5 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.41583098818374276	[491]	[358,344]	6	hSpCas9	negative selection	925416
5457080	5457103	9	+	26627737	GBM cells	viability after 13 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-0.09036092673317331	[86]	[29,55]	-1	hSpCas9	negative selection	1007729
5465504	5465527	9	-	26627737	GBM cells	viability after 13 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.24802354169993074	[200]	[123,133]	3	hSpCas9	negative selection	1007730
5465566	5465589	9	-	26627737	GBM cells	viability after 13 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.06393789302756492	[491]	[320,201]	0	hSpCas9	negative selection	1007731
5457080	5457103	9	+	26627737	GBM cells	viability after 21 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	0.10215185166195684	[86]	[56,44]	1	hSpCas9	negative selection	1090044
5465504	5465527	9	-	26627737	GBM cells	viability after 21 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	1.0556594775019823	[200]	[238,215]	9	hSpCas9	negative selection	1090045
5465566	5465589	9	-	26627737	GBM cells	viability after 21 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.27365349173488285	[491]	[241,201]	-3	hSpCas9	negative selection	1090046
5457080	5457103	9	+	26627737	RPE1	viability after 9 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	1.2954614464094154	[108]	[88,76]	7	hSpCas9	negative selection	1172359
5465504	5465527	9	-	26627737	RPE1	viability after 9 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.22745967370328213	[545]	[169,238]	1	hSpCas9	negative selection	1172360
5465566	5465589	9	-	26627737	RPE1	viability after 9 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.02312253639597217	[1619]	[262,840]	0	hSpCas9	negative selection	1172361
5457080	5457103	9	+	26627737	RPE1	viability after 12 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	1.3671505314589367	[108]	[76,73]	7	hSpCas9	negative selection	1254674
5465504	5465527	9	-	26627737	RPE1	viability after 12 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.16065491287558759	[545]	[128,200]	1	hSpCas9	negative selection	1254675
5465566	5465589	9	-	26627737	RPE1	viability after 12 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.15854777172552548	[1619]	[319,463]	-1	hSpCas9	negative selection	1254676
5457080	5457103	9	+	26627737	RPE1	viability after 15 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	1.297363192443839	[108]	[87,63]	7	hSpCas9	negative selection	1336989
5465504	5465527	9	-	26627737	RPE1	viability after 15 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-0.1528658077081918	[545]	[86,188]	-1	hSpCas9	negative selection	1336990
5465566	5465589	9	-	26627737	RPE1	viability after 15 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.2618230517908692	[1619]	[454,311]	-2	hSpCas9	negative selection	1336991
5457080	5457103	9	+	26627737	RPE1	viability after 18 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	0.5115204168513383	[108]	[39,43]	3	hSpCas9	negative selection	1419304
5465504	5465527	9	-	26627737	RPE1	viability after 18 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.4417583939579519	[545]	[174,226]	3	hSpCas9	negative selection	1419305
5465566	5465589	9	-	26627737	RPE1	viability after 18 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.5204984249459805	[1619]	[341,264]	-3	hSpCas9	negative selection	1419306
5457080	5457103	9	+	26627737	HeLa	viability after 8 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-0.6628660229834347	[140]	[63,6,49]	-6	hSpCas9	negative selection	1501619
5465504	5465527	9	-	26627737	HeLa	viability after 8 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.1195857154018634	[354]	[174,205,126]	1	hSpCas9	negative selection	1501620
5465566	5465589	9	-	26627737	HeLa	viability after 8 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.5099476936392368	[751]	[714,379,364]	4	hSpCas9	negative selection	1501621
5457080	5457103	9	+	26627737	HeLa	viability after 12 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-1.6004055983047911	[140]	[6,21,27]	-9	hSpCas9	negative selection	1583934
5465504	5465527	9	-	26627737	HeLa	viability after 12 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-0.76726952617251	[354]	[49,128,73]	-6	hSpCas9	negative selection	1583935
5465566	5465589	9	-	26627737	HeLa	viability after 12 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.10594030906533669	[751]	[380,227,406]	0	hSpCas9	negative selection	1583936
5457080	5457103	9	+	26627737	HeLa	viability after 15 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-1.1619414240674584	[140]	[30,30,13]	-7	hSpCas9	negative selection	1666249
5465504	5465527	9	-	26627737	HeLa	viability after 15 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-0.377709996887869	[354]	[146,101,81]	-3	hSpCas9	negative selection	1666250
5465566	5465589	9	-	26627737	HeLa	viability after 15 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.3165621706573716	[751]	[194,153,400]	-3	hSpCas9	negative selection	1666251
5457080	5457103	9	+	26627737	HeLa	viability after 18 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-0.9810715072311817	[140]	[23,29,13]	-7	hSpCas9	negative selection	1748564
5465504	5465527	9	-	26627737	HeLa	viability after 18 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-0.34083912896365876	[354]	[102,85,81]	-3	hSpCas9	negative selection	1748565
5465566	5465589	9	-	26627737	HeLa	viability after 18 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.2756662500621777	[751]	[140,131,400]	-2	hSpCas9	negative selection	1748566
5457080	5457103	9	+	26627737	HCT116	viability after 6 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-1.803214968609991	[108]	[11,0]	-7	hSpCas9	negative selection	1830879
5465504	5465527	9	-	26627737	HCT116	viability after 6 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-0.8952574014327366	[524]	[64,32]	-5	hSpCas9	negative selection	1830880
5465566	5465589	9	-	26627737	HCT116	viability after 6 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	1.7208201277501944	[1074]	[752,448]	8	hSpCas9	negative selection	1830881
5457080	5457103	9	+	26627737	HCT116	viability after 8 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	3.093283809381939	[8]	[31,69,24]	9	hSpCas9	negative selection	1913194
5465504	5465527	9	-	26627737	HCT116	viability after 8 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-0.05412178276484378	[266]	[152,103,167]	0	hSpCas9	negative selection	1913195
5465566	5465589	9	-	26627737	HCT116	viability after 8 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.14273071116596658	[598]	[317,381,391]	1	hSpCas9	negative selection	1913196
5457080	5457103	9	+	26627737	HCT116	viability after 9 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-1.933096526653614	[108]	[15,0]	-8	hSpCas9	negative selection	1995509
5465504	5465527	9	-	26627737	HCT116	viability after 9 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.5621775735136367	[524]	[106,285]	4	hSpCas9	negative selection	1995510
5465566	5465589	9	-	26627737	HCT116	viability after 9 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.28116693436434304	[1074]	[195,267]	-2	hSpCas9	negative selection	1995511
5457080	5457103	9	+	26627737	HCT116	viability after 12 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	3.2724669566560274	[8]	[41,68,26]	9	hSpCas9	negative selection	2077824
5465504	5465527	9	-	26627737	HCT116	viability after 12 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-0.34079184939732576	[266]	[112,102,115]	-4	hSpCas9	negative selection	2077825
5465566	5465589	9	-	26627737	HCT116	viability after 12 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.14410673018621978	[598]	[404,324,307]	1	hSpCas9	negative selection	2077826
5457080	5457103	9	+	26627737	HCT116	viability after 15 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	3.6110850502587164	[8]	[26,88,68]	9	hSpCas9	negative selection	2160139
5465504	5465527	9	-	26627737	HCT116	viability after 15 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-0.40293574018958767	[266]	[171,88,93]	-4	hSpCas9	negative selection	2160140
5465566	5465589	9	-	26627737	HCT116	viability after 15 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.12389367412423935	[598]	[299,403,410]	1	hSpCas9	negative selection	2160141
5457080	5457103	9	+	26627737	HCT116	viability after 18 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	1.4266047937017663	[8]	[1,24,6]	8	hSpCas9	negative selection	2242454
5465504	5465527	9	-	26627737	HCT116	viability after 18 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-0.02389124580276883	[266]	[199,95,84]	0	hSpCas9	negative selection	2242455
5465566	5465589	9	-	26627737	HCT116	viability after 18 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.7233805628060206	[598]	[589,383,465]	6	hSpCas9	negative selection	2242456
5462882	5462905	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACATGTCAGTTCATGTTCAGAGG	CD274	ENSG00000120217	-0.05386381539034608	[3,3]	[3,1]	0	hSpCas9	positive selection	2977634
5456145	5456168	9	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.25417283808532204	[5,5]	[5,5]	5	hSpCas9	positive selection	2977635
5462948	5462971	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.24450689073119325	[3,3]	[3,2]	5	hSpCas9	positive selection	2977636
5462905	5462928	9	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.5532227586401104	[3,3]	[1,1]	-7	hSpCas9	positive selection	2977637
5462882	5462905	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACATGTCAGTTCATGTTCAGAGG	CD274	ENSG00000120217	-0.031313739062648296	[3,3]	[3,1]	0	hSpCas9	positive selection	3045492
5456145	5456168	9	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.9254006811435973	[5,5]	[4,9]	9	hSpCas9	positive selection	3045493
5462948	5462971	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	-0.3353863444075938	[3,3]	[3,0]	-5	hSpCas9	positive selection	3045494
5462905	5462928	9	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	0.18859238621724275	[3,3]	[3,2]	3	hSpCas9	positive selection	3045495
5456145	5456168		-	24336571	A375	resistance to PLX after 7 days	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.12125600698106509	[31,28]	[23,30]	-4	hSpCas9	positive selection	3104040
5457245	5457268		-	24336571	A375	resistance to PLX after 7 days	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.2523378118313941	[13,11]	[15,13]	7	hSpCas9	positive selection	3104041
5466801	5466824		-	24336571	A375	resistance to PLX after 7 days	GCTTCTTTGAGTTTGTATCTTGG	CD274	ENSG00000120217	-0.20283417436259255	[5,8]	[5,5]	-6	hSpCas9	positive selection	3104042
5457360	5457383		+	24336571	A375	resistance to PLX after 7 days	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-0.12008361040289012	[13,15]	[15,11]	-4	hSpCas9	positive selection	3104043
5456130	5456153		+	24336571	A375	resistance to PLX after 7 days	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	-0.12544835764462647	[26,21]	[19,24]	-4	hSpCas9	positive selection	3104044
5466759	5466782		+	24336571	A375	resistance to PLX after 7 days	TTTTTCTCAAGGGAGAATGATGG	CD274	ENSG00000120217	-0.07939584362434243	[13,14]	[14,11]	-2	hSpCas9	positive selection	3104045
5456145	5456168		-	24336571	A375	resistance to PLX after 14 days	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.7611583108348798	[38,25]	[9,6]	-8	hSpCas9	positive selection	3161833
5457245	5457268		-	24336571	A375	resistance to PLX after 14 days	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.8878277687615088	[14,15]	[12,13]	7	hSpCas9	positive selection	3161834
5466801	5466824		-	24336571	A375	resistance to PLX after 14 days	GCTTCTTTGAGTTTGTATCTTGG	CD274	ENSG00000120217	-0.4658697091467589	[8,9]	[1,3]	-5	hSpCas9	positive selection	3161835
5457360	5457383		+	24336571	A375	resistance to PLX after 14 days	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-0.4832066965373696	[10,16]	[4,2]	-6	hSpCas9	positive selection	3161836
5456130	5456153		+	24336571	A375	resistance to PLX after 14 days	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.5162928839273937	[18,26]	[15,14]	5	hSpCas9	positive selection	3161837
5466759	5466782		+	24336571	A375	resistance to PLX after 14 days	TTTTTCTCAAGGGAGAATGATGG	CD274	ENSG00000120217	0.7351258141268162	[10,11]	[7,9]	6	hSpCas9	positive selection	3161838
5456145	5456168		-	24336571	A375	viability after 7 days	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.17508433381543242	[35]	[31,28]	-2	hSpCas9	negative selection	3219626
5457245	5457268		-	24336571	A375	viability after 7 days	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.26392858981256356	[15]	[13,11]	-4	hSpCas9	negative selection	3219627
5466801	5466824		-	24336571	A375	viability after 7 days	GCTTCTTTGAGTTTGTATCTTGG	CD274	ENSG00000120217	-0.18282987862174327	[8]	[5,8]	-3	hSpCas9	negative selection	3219628
5457360	5457383		+	24336571	A375	viability after 7 days	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.12462189361980881	[13]	[13,15]	2	hSpCas9	negative selection	3219629
5456130	5456153		+	24336571	A375	viability after 7 days	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	-0.4624902895953865	[35]	[26,21]	-6	hSpCas9	negative selection	3219630
5466759	5466782		+	24336571	A375	viability after 7 days	TTTTTCTCAAGGGAGAATGATGG	CD274	ENSG00000120217	0.14386411804209293	[13]	[13,14]	2	hSpCas9	negative selection	3219631
5456145	5456168		-	24336571	A375	viability after 14 days	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.07162508334476558	[35]	[38,25]	-1	hSpCas9	negative selection	3277419
5457245	5457268		-	24336571	A375	viability after 14 days	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.03374789106497034	[15]	[14,15]	0	hSpCas9	negative selection	3277420
5466801	5466824		-	24336571	A375	viability after 14 days	GCTTCTTTGAGTTTGTATCTTGG	CD274	ENSG00000120217	0.21376690333428044	[8]	[8,9]	2	hSpCas9	negative selection	3277421
5457360	5457383		+	24336571	A375	viability after 14 days	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.0051886993800678155	[13]	[10,16]	0	hSpCas9	negative selection	3277422
5456130	5456153		+	24336571	A375	viability after 14 days	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	-0.5441685951868216	[35]	[18,26]	-6	hSpCas9	negative selection	3277423
5466759	5466782		+	24336571	A375	viability after 14 days	TTTTTCTCAAGGGAGAATGATGG	CD274	ENSG00000120217	-0.14733645610172824	[13]	[10,11]	-2	hSpCas9	negative selection	3277424
5457360	5457383	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-1.3069353804118895	[382,373]	[0,0]	-8	hSpCas9	positive selection	3341998
5457245	5457268	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.1399462400456618	[115,161]	[0,0]	0	hSpCas9	positive selection	3341999
5463096	5463119	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.20836750044998623	[119,144]	[0,0]	1	hSpCas9	positive selection	3342000
5462918	5462941	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.46291034509572904	[110,110]	[0,0]	2	hSpCas9	positive selection	3361227
5456130	5456153	9	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	-2.1856172844028934	[695,695]	[0,0]	-9	hSpCas9	positive selection	3361228
5456145	5456168	9	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.19123702098806272	[133,133]	[0,0]	1	hSpCas9	positive selection	3361229
5462882	5462905	9	-	26780180	HT29	viability (Avana library 4 designs)	ACATGTCAGTTCATGTTCAGAGG	CD274	ENSG00000120217	0.0284616027258924	[]	[]	0	hSpCas9	negative selection	3413937
5456145	5456168	9	-	26780180	HT29	viability (Avana library 4 designs)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.126919730442178	[]	[]	-2	hSpCas9	negative selection	3413938
5462947	5462970	9	+	26780180	HT29	viability (Avana library 4 designs)	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	1.49602152303695	[]	[]	6	hSpCas9	negative selection	3413939
5462904	5462927	9	+	26780180	HT29	viability (Avana library 4 designs)	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	2.47505322708401	[]	[]	8	hSpCas9	negative selection	3413940
5462904	5462927	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	1.53334566633239	[]	[]	2	hSpCas9	negative selection	3490209
5456145	5456168	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.774145937758351	[]	[]	1	hSpCas9	negative selection	3490210
5462882	5462905	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACATGTCAGTTCATGTTCAGAGG	CD274	ENSG00000120217	4.23574536818123	[]	[]	7	hSpCas9	negative selection	3490211
5462947	5462970	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.622165108882302	[]	[]	0	hSpCas9	negative selection	3490212
5462853	5462876	9	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCCACAACCAAAATTCTTTGG	CD274	ENSG00000120217	-5.7342707726002	[]	[]	-6	hSpCas9	negative selection	3490213
5456144	5456167	9	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTACTGGCATTTGCTGAACGG	CD274	ENSG00000120217	3.38292569950303	[]	[]	5	hSpCas9	negative selection	3490214
5462904	5462927	9	+	26780180	A375	viability (Avana lentiGuide)	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	11.7136941293222	[]	[]	7	hSpCas9	negative selection	3598868
5456145	5456168	9	-	26780180	A375	viability (Avana lentiGuide)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	1.22903576085099	[]	[]	1	hSpCas9	negative selection	3598869
5462882	5462905	9	-	26780180	A375	viability (Avana lentiGuide)	ACATGTCAGTTCATGTTCAGAGG	CD274	ENSG00000120217	-0.107051228636105	[]	[]	0	hSpCas9	negative selection	3598870
5462947	5462970	9	+	26780180	A375	viability (Avana lentiGuide)	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	-4.65109788230347	[]	[]	-7	hSpCas9	negative selection	3598871
5462853	5462876	9	-	26780180	A375	viability (Avana lentiGuide)	GATCCACAACCAAAATTCTTTGG	CD274	ENSG00000120217	-7.00623070378683	[]	[]	-9	hSpCas9	negative selection	3598872
5456144	5456167	9	+	26780180	A375	viability (Avana lentiGuide)	ACCTACTGGCATTTGCTGAACGG	CD274	ENSG00000120217	-5.95172144706926	[]	[]	-8	hSpCas9	negative selection	3598873
5462904	5462927	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.18737087940996577	[4]	[4,3]	-3	hSpCas9	positive selection	3707527
5456145	5456168	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.06792598271219998	[5]	[5,4]	-1	hSpCas9	positive selection	3707528
5462882	5462905	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACATGTCAGTTCATGTTCAGAGG	CD274	ENSG00000120217	0.14544143194083703	[5]	[6,5]	4	hSpCas9	positive selection	3707529
5462947	5462970	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	-0.046823542379168456	[5]	[5,3]	-1	hSpCas9	positive selection	3707530
5462853	5462876	9	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCCACAACCAAAATTCTTTGG	CD274	ENSG00000120217	-0.3863419432593695	[7]	[5,5]	-5	hSpCas9	positive selection	3707531
5456144	5456167	9	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTACTGGCATTTGCTGAACGG	CD274	ENSG00000120217	0.06517583179859929	[6]	[6,6]	1	hSpCas9	positive selection	3707532
5462904	5462927	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.19847029608554118	[5]	[3,4]	-3	hSpCas9	positive selection	3816134
5456145	5456168	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.06894955708911626	[6]	[7,4]	1	hSpCas9	positive selection	3816135
5462882	5462905	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACATGTCAGTTCATGTTCAGAGG	CD274	ENSG00000120217	-0.8391006848250248	[5]	[0,3]	-8	hSpCas9	positive selection	3816136
5462947	5462970	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.18276216204975476	[4]	[3,4]	4	hSpCas9	positive selection	3816137
5462853	5462876	9	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCCACAACCAAAATTCTTTGG	CD274	ENSG00000120217	0.39430483229520474	[6]	[7,7]	9	hSpCas9	positive selection	3816138
5456144	5456167	9	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTACTGGCATTTGCTGAACGG	CD274	ENSG00000120217	0.3908196943611104	[6]	[7,6]	9	hSpCas9	positive selection	3816139
5462918	5462941	9	+	26780180	A375	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.607379493248619	[]	[]	2	hSpCas9	negative selection	3924312
5456145	5456168	9	-	26780180	A375	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	1.29334411472641	[]	[]	7	hSpCas9	negative selection	3924313
5457245	5457268	9	-	26780180	A375	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.543461995764421	[]	[]	1	hSpCas9	negative selection	3924314
5463096	5463119	9	-	26780180	A375	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.487779851510246	[]	[]	1	hSpCas9	negative selection	3924315
5457360	5457383	9	+	26780180	A375	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	1.2142130276689	[]	[]	6	hSpCas9	negative selection	3924316
5456130	5456153	9	+	26780180	A375	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.78660625086657	[]	[]	3	hSpCas9	negative selection	3924317
5462918	5462941	9	+	26780180	HT29	viability (GeCKOv2 library)	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.826181472216519	[]	[]	3	hSpCas9	negative selection	4032278
5456145	5456168	9	-	26780180	HT29	viability (GeCKOv2 library)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	1.22773111096552	[]	[]	6	hSpCas9	negative selection	4032279
5457245	5457268	9	-	26780180	HT29	viability (GeCKOv2 library)	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.688133825835354	[]	[]	2	hSpCas9	negative selection	4032280
5463096	5463119	9	-	26780180	HT29	viability (GeCKOv2 library)	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.689674011296653	[]	[]	2	hSpCas9	negative selection	4032281
5457360	5457383	9	+	26780180	HT29	viability (GeCKOv2 library)	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.0945985410122387	[]	[]	0	hSpCas9	negative selection	4032282
5456130	5456153	9	+	26780180	HT29	viability (GeCKOv2 library)	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	-0.158128680028958	[]	[]	-4	hSpCas9	negative selection	4032283
5456145	5456168	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.12154528622427943	[4]	[2,2]	-3	hSpCas9	positive selection	4126029
5457245	5457268	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.13704343294871865	[3]	[1,3]	3	hSpCas9	positive selection	4126030
5466801	5466824	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTCTTTGAGTTTGTATCTTGG	CD274	ENSG00000120217	0.16340965378528965	[2]	[2,1]	4	hSpCas9	positive selection	4126031
5457360	5457383	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-0.1120316441214971	[3]	[2,1]	-3	hSpCas9	positive selection	4126032
5456130	5456153	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.3569056379116272	[3]	[2,3]	8	hSpCas9	positive selection	4126033
5466759	5466782	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTTTTCTCAAGGGAGAATGATGG	CD274	ENSG00000120217	-0.22926661690139344	[4]	[1,3]	-5	hSpCas9	positive selection	4126034
5456145	5456168	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	1.1507143059675695	[5]	[5,4,4,5]	8	hSpCas9	positive selection	4190051
5457245	5457268	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.20418614913336824	[3]	[1,1,2,0]	1	hSpCas9	positive selection	4190052
5466801	5466824	9	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTCTTTGAGTTTGTATCTTGG	CD274	ENSG00000120217	0.9217496980297502	[2]	[0,0,0,3]	6	hSpCas9	positive selection	4190053
5457360	5457383	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.056517526983746603	[3]	[1,4,1,0]	0	hSpCas9	positive selection	4190054
5456130	5456153	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.7999239600293709	[4]	[1,2,2,4]	5	hSpCas9	positive selection	4190055
5466759	5466782	9	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTTTTCTCAAGGGAGAATGATGG	CD274	ENSG00000120217	0.6755226590523715	[3]	[0,0,2,3]	4	hSpCas9	positive selection	4190056
5457360	5457383	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.10150585326367056	[4]	[4,3]	2	hSpCas9	positive selection	4262016
5457245	5457268	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.2065052040656765	[3]	[2,2]	4	hSpCas9	positive selection	4262017
5463096	5463119	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.4087613480573725	[2]	[2,2]	8	hSpCas9	positive selection	4262018
5462918	5462941	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.25882173110345447	[3]	[3,2]	5	hSpCas9	positive selection	4326293
5456130	5456153	9	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.19795576361042638	[4]	[4,3]	4	hSpCas9	positive selection	4326294
5456145	5456168	9	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.15869577301388638	[2]	[2,0]	-3	hSpCas9	positive selection	4326295
5462875	5462897	9	-	27760321	OCIAML3	viability	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	0.35842554309254393	[338,300]	[259,398]	4	hSpCas9	negative selection	4387325
5462893	5462915	9	+	27760321	OCIAML3	viability	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.5042849330838756	[711,583]	[595,870]	6	hSpCas9	negative selection	4387326
5462921	5462943	9	-	27760321	OCIAML3	viability	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	1.1068515099949252	[986,836]	[1417,1677]	9	hSpCas9	negative selection	4387327
5462980	5463002	9	+	27760321	OCIAML3	viability	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	0.9457639480410647	[323,243]	[389,468]	9	hSpCas9	negative selection	4387328
5463096	5463118	9	-	27760321	OCIAML3	viability	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.9649552276938087	[378,366]	[369,831]	9	hSpCas9	negative selection	4387329
5457219	5457241	9	+	27760321	OCIAML3	viability	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	0.4276790853756428	[481,430]	[387,598]	5	hSpCas9	negative selection	4387330
5462875	5462897	9	-	27760321	OCIAML2	viability	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	1.1008716465486263	[338,300]	[565,538]	9	hSpCas9	negative selection	4470788
5462893	5462915	9	+	27760321	OCIAML2	viability	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.060706982663925824	[711,583]	[487,617]	0	hSpCas9	negative selection	4470789
5462921	5462943	9	-	27760321	OCIAML2	viability	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	1.0843681789578312	[986,836]	[1435,1720]	9	hSpCas9	negative selection	4470790
5462980	5463002	9	+	27760321	OCIAML2	viability	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	0.4978443207832066	[323,243]	[234,435]	6	hSpCas9	negative selection	4470791
5463096	5463118	9	-	27760321	OCIAML2	viability	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6142662536590837	[378,366]	[448,480]	8	hSpCas9	negative selection	4470792
5457219	5457241	9	+	27760321	OCIAML2	viability	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	0.8710034432823317	[481,430]	[617,748]	9	hSpCas9	negative selection	4470793
5462875	5462897	9	-	27760321	MV411	viability	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	0.45521177540284097	[338,300]	[346,201]	3	hSpCas9	negative selection	4554251
5462893	5462915	9	+	27760321	MV411	viability	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	1.3424849138299964	[711,583]	[1260,805]	8	hSpCas9	negative selection	4554252
5462921	5462943	9	-	27760321	MV411	viability	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	1.0539090763572627	[986,836]	[1432,962]	7	hSpCas9	negative selection	4554253
5462980	5463002	9	+	27760321	MV411	viability	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	1.3650305199855626	[323,243]	[650,219]	8	hSpCas9	negative selection	4554254
5463096	5463118	9	-	27760321	MV411	viability	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	1.0128382039110417	[378,366]	[571,385]	7	hSpCas9	negative selection	4554255
5457219	5457241	9	+	27760321	MV411	viability	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	0.8555250564387682	[481,430]	[505,601]	6	hSpCas9	negative selection	4554256
5462875	5462897	9	-	27760321	HL60	viability	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	0.6395027161775378	[338,300]	[391,421]	7	hSpCas9	negative selection	4637714
5462893	5462915	9	+	27760321	HL60	viability	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.05970612420472243	[711,583]	[334,775]	0	hSpCas9	negative selection	4637715
5462921	5462943	9	-	27760321	HL60	viability	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	0.6347280599670992	[986,836]	[1208,1092]	7	hSpCas9	negative selection	4637716
5462980	5463002	9	+	27760321	HL60	viability	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	-0.025661282243071737	[323,243]	[209,242]	0	hSpCas9	negative selection	4637717
5463096	5463118	9	-	27760321	HL60	viability	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6075525864005344	[378,366]	[536,388]	7	hSpCas9	negative selection	4637718
5457219	5457241	9	+	27760321	HL60	viability	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	1.021594177214963	[481,430]	[774,735]	9	hSpCas9	negative selection	4637719
5462875	5462897	9	-	27760321	HT1080	viability	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	-0.008486602122854126	[300,234]	[87,125]	0	hSpCas9	negative selection	4721177
5462893	5462915	9	+	27760321	HT1080	viability	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	2.035691974153494	[583,455]	[825,874]	9	hSpCas9	negative selection	4721178
5462921	5462943	9	-	27760321	HT1080	viability	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	0.012150745294568832	[836,652]	[473,107]	0	hSpCas9	negative selection	4721179
5462980	5463002	9	+	27760321	HT1080	viability	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	2.1996708602299067	[243,190]	[473,314]	9	hSpCas9	negative selection	4721180
5463096	5463118	9	-	27760321	HT1080	viability	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.8260241453000268	[366,286]	[303,150]	4	hSpCas9	negative selection	4721181
5457219	5457241	9	+	27760321	HT1080	viability	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	-0.40245242131412273	[430,336]	[120,109]	-2	hSpCas9	negative selection	4721182
5462875	5462897	9	-	27760321	HT29	viability after 7 days	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	-0.007423076445328469	[300,234]	[420,526,98]	0	hSpCas9	negative selection	4804640
5462893	5462915	9	+	27760321	HT29	viability after 7 days	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.1055667756333718	[583,455]	[758,758,646]	1	hSpCas9	negative selection	4804641
5462921	5462943	9	-	27760321	HT29	viability after 7 days	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	0.762406042361931	[836,652]	[1748,1651,1492]	9	hSpCas9	negative selection	4804642
5462980	5463002	9	+	27760321	HT29	viability after 7 days	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	0.5315521134862399	[243,190]	[571,316,348]	7	hSpCas9	negative selection	4804643
5463096	5463118	9	-	27760321	HT29	viability after 7 days	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.2653752797184771	[366,286]	[405,580,513]	4	hSpCas9	negative selection	4804644
5457219	5457241	9	+	27760321	HT29	viability after 7 days	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	-0.51372856088193	[430,336]	[345,311,377]	-6	hSpCas9	negative selection	4804645
5462875	5462897	9	-	27760321	HT29	viability after 25 days	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	0.059004169595924305	[300,234]	[362,305,280]	0	hSpCas9	negative selection	4888103
5462893	5462915	9	+	27760321	HT29	viability after 25 days	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.3661779556727397	[583,455]	[510,1077,718]	4	hSpCas9	negative selection	4888104
5462921	5462943	9	-	27760321	HT29	viability after 25 days	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	1.2578172660861322	[836,652]	[2055,1920,2136]	9	hSpCas9	negative selection	4888105
5462980	5463002	9	+	27760321	HT29	viability after 25 days	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	0.8653281083262985	[243,190]	[517,459,366]	8	hSpCas9	negative selection	4888106
5463096	5463118	9	-	27760321	HT29	viability after 25 days	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6416183876523635	[366,286]	[366,621,794]	7	hSpCas9	negative selection	4888107
5457219	5457241	9	+	27760321	HT29	viability after 25 days	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	-0.0684080798516461	[430,336]	[493,374,376]	0	hSpCas9	negative selection	4888108
5462875	5462897	9	-	27760321	HT29	viability after 22 days	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	0.2708998422854543	[300,234]	[437,383,296]	3	hSpCas9	negative selection	4971566
5462893	5462915	9	+	27760321	HT29	viability after 22 days	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.16766953895860714	[583,455]	[558,989,477]	1	hSpCas9	negative selection	4971567
5462921	5462943	9	-	27760321	HT29	viability after 22 days	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	1.1552009556380642	[836,652]	[1775,1967,2014]	9	hSpCas9	negative selection	4971568
5462980	5463002	9	+	27760321	HT29	viability after 22 days	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	0.765683465913034	[243,190]	[414,339,528]	8	hSpCas9	negative selection	4971569
5463096	5463118	9	-	27760321	HT29	viability after 22 days	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.8208796237900877	[366,286]	[446,740,822]	8	hSpCas9	negative selection	4971570
5457219	5457241	9	+	27760321	HT29	viability after 22 days	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	-0.07949328214461711	[430,336]	[328,509,423]	-1	hSpCas9	negative selection	4971571
5462875	5462897	9	-	27760321	HT29	viability after 19 days	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	0.6868911506810849	[300,234]	[387,723,361]	7	hSpCas9	negative selection	5055029
5462893	5462915	9	+	27760321	HT29	viability after 19 days	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.5545275492252605	[583,455]	[627,1410,566]	5	hSpCas9	negative selection	5055030
5462921	5462943	9	-	27760321	HT29	viability after 19 days	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	1.1042660863628628	[836,652]	[2060,1919,1547]	9	hSpCas9	negative selection	5055031
5462980	5463002	9	+	27760321	HT29	viability after 19 days	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	1.2190190637769462	[243,190]	[516,269,929]	9	hSpCas9	negative selection	5055032
5463096	5463118	9	-	27760321	HT29	viability after 19 days	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.3768169164236719	[366,286]	[539,319,597]	3	hSpCas9	negative selection	5055033
5457219	5457241	9	+	27760321	HT29	viability after 19 days	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	0.34734580941036153	[430,336]	[310,671,662]	3	hSpCas9	negative selection	5055034
5462875	5462897	9	-	27760321	HT29	viability after 16 days	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	-0.2199041424838094	[300,234]	[231,215,322]	-2	hSpCas9	negative selection	5138492
5462893	5462915	9	+	27760321	HT29	viability after 16 days	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.29887726365896095	[583,455]	[574,858,695]	3	hSpCas9	negative selection	5138493
5462921	5462943	9	-	27760321	HT29	viability after 16 days	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	0.969310103667471	[836,652]	[1455,1202,2230]	9	hSpCas9	negative selection	5138494
5462980	5463002	9	+	27760321	HT29	viability after 16 days	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	1.1281281198770794	[243,190]	[614,366,625]	9	hSpCas9	negative selection	5138495
5463096	5463118	9	-	27760321	HT29	viability after 16 days	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.7863407143492646	[366,286]	[511,738,627]	8	hSpCas9	negative selection	5138496
5457219	5457241	9	+	27760321	HT29	viability after 16 days	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	-0.006547315891124589	[430,336]	[436,426,419]	0	hSpCas9	negative selection	5138497
5462875	5462897	9	-	27760321	HT29	viability after 13 days	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	-0.05803416170571385	[300,234]	[303,311,280]	0	hSpCas9	negative selection	5221955
5462893	5462915	9	+	27760321	HT29	viability after 13 days	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.13780885308930724	[583,455]	[511,790,686]	1	hSpCas9	negative selection	5221956
5462921	5462943	9	-	27760321	HT29	viability after 13 days	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	1.0717776736348237	[836,652]	[1592,1916,1932]	9	hSpCas9	negative selection	5221957
5462980	5463002	9	+	27760321	HT29	viability after 13 days	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	0.6355364022537541	[243,190]	[364,313,490]	8	hSpCas9	negative selection	5221958
5463096	5463118	9	-	27760321	HT29	viability after 13 days	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.36720903984605036	[366,286]	[406,516,540]	4	hSpCas9	negative selection	5221959
5457219	5457241	9	+	27760321	HT29	viability after 13 days	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	-0.16010012646765948	[430,336]	[189,443,552]	-2	hSpCas9	negative selection	5221960
5462875	5462897	9	-	27760321	HT29	viability after 10 days	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	-0.048597940047552024	[300,234]	[348,280,338]	0	hSpCas9	negative selection	5305418
5462893	5462915	9	+	27760321	HT29	viability after 10 days	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.6666558575300469	[583,455]	[651,1164,1272]	8	hSpCas9	negative selection	5305419
5462921	5462943	9	-	27760321	HT29	viability after 10 days	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	0.9311117942314528	[836,652]	[1702,1676,1933]	9	hSpCas9	negative selection	5305420
5462980	5463002	9	+	27760321	HT29	viability after 10 days	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	0.6065178359993454	[243,190]	[345,351,537]	8	hSpCas9	negative selection	5305421
5463096	5463118	9	-	27760321	HT29	viability after 10 days	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.3831934825110219	[366,286]	[380,588,626]	5	hSpCas9	negative selection	5305422
5457219	5457241	9	+	27760321	HT29	viability after 10 days	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	0.13272271247799555	[430,336]	[623,400,547]	1	hSpCas9	negative selection	5305423
5462875	5462897	9	-	27760321	MOLM13	viability	GTTCATGTTCAGAGGTGACTGG	CD274	ENSG00000120217	0.22938341447257915	[338,300]	[280,151]	1	hSpCas9	negative selection	5388881
5462893	5462915	9	+	27760321	MOLM13	viability	GAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.5024702424227275	[711,583]	[576,462]	3	hSpCas9	negative selection	5388882
5462921	5462943	9	-	27760321	MOLM13	viability	GTCCAGATGACTTCGGCCTTGG	CD274	ENSG00000120217	1.1701044934738802	[986,836]	[1565,802]	7	hSpCas9	negative selection	5388883
5462980	5463002	9	+	27760321	MOLM13	viability	ACCACCAATTCCAAGAGAGAGG	CD274	ENSG00000120217	1.3289361945877385	[323,243]	[678,160]	8	hSpCas9	negative selection	5388884
5463096	5463118	9	-	27760321	MOLM13	viability	GATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.9616199301387651	[378,366]	[327,480]	6	hSpCas9	negative selection	5388885
5457219	5457241	9	+	27760321	MOLM13	viability	ATTCAATTTGTGCATGGAGAGG	CD274	ENSG00000120217	0.9527958516232888	[481,430]	[364,610]	6	hSpCas9	negative selection	5388886
5451029	5451052	9	+	27661255	K562	viability	GCAGGTCCAGGATCCCTGAACGG	CD274	ENSG00000120217	-0.09203625510928848	[799,587]	[509,533]	-3	dCas9-KRAB	negative selection	5469398
5450566	5450589	9	-	27661255	K562	viability	GGACAGAAGCGCGGCTGGTGCGG	CD274	ENSG00000120217	0.012137523913363646	[1107,1234]	[997,893]	0	dCas9-KRAB	negative selection	5469399
5450631	5450654	9	-	27661255	K562	viability	GCGAGCTAGCCAGAGATACTGGG	CD274	ENSG00000120217	0.2676455825207822	[603,978]	[806,709]	8	dCas9-KRAB	negative selection	5469400
5457360	5457383	9	+	27260156	BXPC3	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.14547456332636322	[1369]	[1341,1685,1444,1911]	3	hSpCas9	negative selection	5534476
5457245	5457268	9	-	27260156	BXPC3	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.07221150553893035	[534]	[458,487,720,718]	1	hSpCas9	negative selection	5534477
5463096	5463119	9	-	27260156	BXPC3	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.48478675982107444	[284]	[319,483,370,506]	8	hSpCas9	negative selection	5534478
5462918	5462941	9	+	27260156	BXPC3	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.16379969287120053	[482]	[529,552,536,653]	3	hSpCas9	negative selection	5598753
5456130	5456153	9	+	27260156	BXPC3	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.21228029358187728	[1434]	[1640,1479,1663,2242]	5	hSpCas9	negative selection	5598754
5456145	5456168	9	-	27260156	BXPC3	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.03844826471177887	[264]	[265,219,279,388]	0	hSpCas9	negative selection	5598755
5457360	5457383	9	+	27260156	A673	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.09458454128083837	[1369]	[1735,1737,1674,1878]	2	hSpCas9	negative selection	5655727
5457245	5457268	9	-	27260156	A673	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.2637359495720943	[534]	[873,672,717,836]	6	hSpCas9	negative selection	5655728
5463096	5463119	9	-	27260156	A673	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.5245533382264382	[284]	[560,398,483,536]	9	hSpCas9	negative selection	5655729
5462918	5462941	9	+	27260156	A673	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.15934692031790113	[482]	[741,556,620,684]	4	hSpCas9	negative selection	5720004
5456130	5456153	9	+	27260156	A673	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	-0.02380758536534322	[1434]	[1676,1602,1659,1844]	0	hSpCas9	negative selection	5720005
5456145	5456168	9	-	27260156	A673	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.005928841072237567	[264]	[350,278,306,335]	0	hSpCas9	negative selection	5720006
5457360	5457383	9	+	27260156	A375	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-0.26392160738992554	[1369]	[1504,1365,1337,1144]	-4	hSpCas9	negative selection	5776978
5457245	5457268	9	-	27260156	A375	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.20257510059738448	[534]	[677,791,875,556]	3	hSpCas9	negative selection	5776979
5463096	5463119	9	-	27260156	A375	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.9675248720841695	[284]	[472,873,679,608]	9	hSpCas9	negative selection	5776980
5462918	5462941	9	+	27260156	A375	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.3782083282892259	[482]	[863,834,603,651]	5	hSpCas9	negative selection	5841255
5456130	5456153	9	+	27260156	A375	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.2593190010790518	[1434]	[2301,2104,1771,1869]	4	hSpCas9	negative selection	5841256
5456145	5456168	9	-	27260156	A375	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.3203570294297037	[264]	[182,299,327,192]	-4	hSpCas9	negative selection	5841257
5457360	5457383	9	+	27260156	COLO741	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.21517417949737871	[1369]	[2464,1932,1750]	4	hSpCas9	negative selection	5898229
5457245	5457268	9	-	27260156	COLO741	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.13213498927680004	[534]	[773,647,471]	-3	hSpCas9	negative selection	5898230
5463096	5463119	9	-	27260156	COLO741	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6699753387197496	[284]	[542,627,563]	9	hSpCas9	negative selection	5898231
5462918	5462941	9	+	27260156	COLO741	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.18651283079670522	[482]	[812,480,811]	4	hSpCas9	negative selection	5962506
5456130	5456153	9	+	27260156	COLO741	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.11522813188779435	[1434]	[1798,2083,2049]	2	hSpCas9	negative selection	5962507
5456145	5456168	9	-	27260156	COLO741	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.1880754168338873	[264]	[491,382,296]	4	hSpCas9	negative selection	5962508
5457360	5457383	9	+	27260156	CAL120	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-0.05416980050946574	[1369]	[2343,1441,1251]	-1	hSpCas9	negative selection	6019480
5457245	5457268	9	-	27260156	CAL120	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.1166947808304152	[534]	[516,684,624]	-2	hSpCas9	negative selection	6019481
5463096	5463119	9	-	27260156	CAL120	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6339725750314389	[284]	[781,537,368]	8	hSpCas9	negative selection	6019482
5462918	5462941	9	+	27260156	CAL120	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.3719467443474797	[482]	[884,897,569]	5	hSpCas9	negative selection	6083757
5456130	5456153	9	+	27260156	CAL120	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.16813894566876897	[1434]	[2449,1730,1905]	2	hSpCas9	negative selection	6083758
5456145	5456168	9	-	27260156	CAL120	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.0928989677525075	[264]	[134,404,479]	1	hSpCas9	negative selection	6083759
5457360	5457383	9	+	27260156	CADOES1	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.021140413347690457	[1369]	[1027,1464,1385,1293]	0	hSpCas9	negative selection	6140731
5457245	5457268	9	-	27260156	CADOES1	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.10488210879463983	[534]	[443,495,576,626]	1	hSpCas9	negative selection	6140732
5463096	5463119	9	-	27260156	CADOES1	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.606695031922784	[284]	[373,360,335,548]	8	hSpCas9	negative selection	6140733
5462918	5462941	9	+	27260156	CADOES1	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.471922525840574	[482]	[753,669,571,490]	7	hSpCas9	negative selection	6205008
5456130	5456153	9	+	27260156	CADOES1	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.19504341758563082	[1434]	[1532,1505,1372,1705]	3	hSpCas9	negative selection	6205009
5456145	5456168	9	-	27260156	CADOES1	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.042823513663096446	[264]	[252,218,167,319]	0	hSpCas9	negative selection	6205010
5457360	5457383	9	+	27260156	EWS502	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.08172135027929484	[1369]	[1287,1746,1487,1641]	1	hSpCas9	negative selection	6261982
5457245	5457268	9	-	27260156	EWS502	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.3787444245825606	[534]	[736,770,717,714]	6	hSpCas9	negative selection	6261983
5463096	5463119	9	-	27260156	EWS502	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6558021661802698	[284]	[481,507,444,461]	9	hSpCas9	negative selection	6261984
5462918	5462941	9	+	27260156	EWS502	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.46470356249633066	[482]	[774,538,720,790]	7	hSpCas9	negative selection	6326259
5456130	5456153	9	+	27260156	EWS502	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.2280505589944446	[1434]	[1578,1716,1954,1900]	4	hSpCas9	negative selection	6326260
5456145	5456168	9	-	27260156	EWS502	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.20929806288330155	[264]	[258,304,382,361]	3	hSpCas9	negative selection	6326261
5457360	5457383	9	+	27260156	EW8	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.10907616023508604	[1369]	[1611,1208,838,1232]	2	hSpCas9	negative selection	6383233
5457245	5457268	9	-	27260156	EW8	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.0839509462711695	[534]	[475,462,331,588]	1	hSpCas9	negative selection	6383234
5463096	5463119	9	-	27260156	EW8	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.7197350554494543	[284]	[410,304,273,550]	9	hSpCas9	negative selection	6383235
5462918	5462941	9	+	27260156	EW8	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.2742380939184513	[482]	[494,455,433,515]	5	hSpCas9	negative selection	6447510
5456130	5456153	9	+	27260156	EW8	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.07131293999663435	[1434]	[1271,1277,1155,1194]	1	hSpCas9	negative selection	6447511
5456145	5456168	9	-	27260156	EW8	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.28131692702293054	[264]	[240,285,249,265]	5	hSpCas9	negative selection	6447512
5457360	5457383	9	+	27260156	CORL105	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.19541103788128167	[1369]	[1853,1661,1963,1888]	3	hSpCas9	negative selection	6504484
5457245	5457268	9	-	27260156	CORL105	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.058388983071018474	[534]	[527,472,864,580]	-1	hSpCas9	negative selection	6504485
5463096	5463119	9	-	27260156	CORL105	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.5451342883156203	[284]	[628,364,570,402]	8	hSpCas9	negative selection	6504486
5462918	5462941	9	+	27260156	CORL105	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.3503468139966852	[482]	[895,491,1042,513]	6	hSpCas9	negative selection	6568761
5456130	5456153	9	+	27260156	CORL105	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.08922946633836215	[1434]	[1559,1678,2394,1603]	1	hSpCas9	negative selection	6568762
5456145	5456168	9	-	27260156	CORL105	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.024024032469727064	[264]	[323,360,394,193]	0	hSpCas9	negative selection	6568763
5457360	5457383	9	+	27260156	HS294T	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.44749728512319087	[1369]	[612,782,719,790]	6	hSpCas9	negative selection	6625735
5457245	5457268	9	-	27260156	HS294T	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.09377503632904588	[534]	[195,197,302,181]	1	hSpCas9	negative selection	6625736
5463096	5463119	9	-	27260156	HS294T	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.19595153264746645	[284]	[147,120,124,104]	2	hSpCas9	negative selection	6625737
5462918	5462941	9	+	27260156	HS294T	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.1235183489004264	[482]	[142,234,255,179]	1	hSpCas9	negative selection	6690012
5456130	5456153	9	+	27260156	HS294T	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.280101829448949	[1434]	[492,683,843,691]	4	hSpCas9	negative selection	6690013
5456145	5456168	9	-	27260156	HS294T	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.07222165661647983	[264]	[58,68,119,155]	-1	hSpCas9	negative selection	6690014
5457360	5457383	9	+	27260156	HCC44	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.1082337788034129	[1369]	[1680,1436,2370,1343]	1	hSpCas9	negative selection	6746986
5457245	5457268	9	-	27260156	HCC44	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.16637539193896897	[534]	[498,408,622,646]	-3	hSpCas9	negative selection	6746987
5463096	5463119	9	-	27260156	HCC44	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6683915810286619	[284]	[538,381,476,656]	9	hSpCas9	negative selection	6746988
5462918	5462941	9	+	27260156	HCC44	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.12249489224605462	[482]	[585,570,697,540]	2	hSpCas9	negative selection	6811263
5456130	5456153	9	+	27260156	HCC44	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.22338629618972106	[1434]	[1566,2128,1886,1914]	3	hSpCas9	negative selection	6811264
5456145	5456168	9	-	27260156	HCC44	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.2582767735194128	[264]	[247,237,308,217]	-4	hSpCas9	negative selection	6811265
5457360	5457383	9	+	27260156	G402	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-0.009269874684307622	[1369]	[2164,2017,1332,1235]	0	hSpCas9	negative selection	6868237
5457245	5457268	9	-	27260156	G402	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.4221873430171657	[534]	[1279,981,713,597]	5	hSpCas9	negative selection	6868238
5463096	5463119	9	-	27260156	G402	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	1.3308532844529992	[284]	[886,594,1330,677]	9	hSpCas9	negative selection	6868239
5462918	5462941	9	+	27260156	G402	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.33107297781904665	[482]	[879,683,878,545]	4	hSpCas9	negative selection	6932514
5456130	5456153	9	+	27260156	G402	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.3893151925689988	[1434]	[1698,3613,1875,1981]	5	hSpCas9	negative selection	6932515
5456145	5456168	9	-	27260156	G402	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.26880152577956007	[264]	[280,352,86,353]	-3	hSpCas9	negative selection	6932516
5457360	5457383	9	+	27260156	L33	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.0752946483371566	[1369]	[1411,588,947,1416]	1	hSpCas9	negative selection	6989488
5457245	5457268	9	-	27260156	L33	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.1442232596088193	[534]	[557,149,374,414]	-3	hSpCas9	negative selection	6989489
5463096	5463119	9	-	27260156	L33	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.19563089439432924	[284]	[368,136,203,276]	4	hSpCas9	negative selection	6989490
5462918	5462941	9	+	27260156	L33	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	-0.03147241291037589	[482]	[413,196,331,468]	0	hSpCas9	negative selection	7053765
5456130	5456153	9	+	27260156	L33	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	-0.032397739988110796	[1434]	[1620,535,812,1383]	0	hSpCas9	negative selection	7053766
5456145	5456168	9	-	27260156	L33	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.13675333565928594	[264]	[294,97,104,260]	-3	hSpCas9	negative selection	7053767
5457360	5457383	9	+	27260156	K562	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.07781874002598488	[1369]	[1689,1006,1156,1290]	0	hSpCas9	negative selection	7110739
5457245	5457268	9	-	27260156	K562	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.16790654412986167	[534]	[414,324,426,505]	-2	hSpCas9	negative selection	7110740
5463096	5463119	9	-	27260156	K562	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.7634571337393043	[284]	[590,475,430,253]	8	hSpCas9	negative selection	7110741
5462918	5462941	9	+	27260156	K562	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.6914600604087966	[482]	[808,404,1086,483]	8	hSpCas9	negative selection	7175016
5456130	5456153	9	+	27260156	K562	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.08184259567916996	[1434]	[1355,1249,1408,1363]	1	hSpCas9	negative selection	7175017
5456145	5456168	9	-	27260156	K562	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.4643177789799363	[264]	[103,377,94,115]	-5	hSpCas9	negative selection	7175018
5457360	5457383	9	+	27260156	HT29	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.019467435520377663	[1369]	[1718,1892,1632,1533]	0	hSpCas9	negative selection	7231990
5457245	5457268	9	-	27260156	HT29	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.16670630856422963	[534]	[670,805,792,655]	3	hSpCas9	negative selection	7231991
5463096	5463119	9	-	27260156	HT29	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.4999979648168351	[284]	[499,557,514,400]	8	hSpCas9	negative selection	7231992
5462918	5462941	9	+	27260156	HT29	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.07816364225618376	[482]	[661,643,669,516]	1	hSpCas9	negative selection	7296267
5456130	5456153	9	+	27260156	HT29	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.10532091857269887	[1434]	[2015,2055,1843,1632]	2	hSpCas9	negative selection	7296268
5456145	5456168	9	-	27260156	HT29	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.1090640741161214	[264]	[394,462,331,225]	2	hSpCas9	negative selection	7296269
5457360	5457383	9	+	27260156	MHHES1	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.2286011253150515	[1369]	[2224,1612,1883,1557]	4	hSpCas9	negative selection	7353241
5457245	5457268	9	-	27260156	MHHES1	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.006225275102272554	[534]	[940,564,514,439]	0	hSpCas9	negative selection	7353242
5463096	5463119	9	-	27260156	MHHES1	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.5259324939603076	[284]	[391,575,548,350]	8	hSpCas9	negative selection	7353243
5462918	5462941	9	+	27260156	MHHES1	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.2640555652110368	[482]	[781,899,563,441]	5	hSpCas9	negative selection	7417518
5456130	5456153	9	+	27260156	MHHES1	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.35441872008419373	[1434]	[2299,2440,2002,1639]	6	hSpCas9	negative selection	7417519
5456145	5456168	9	-	27260156	MHHES1	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.05760669411843755	[264]	[284,291,284,356]	1	hSpCas9	negative selection	7417520
5457360	5457383	9	+	27260156	MEWO	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.09369807219418824	[1369]	[1566,1260,1313]	2	hSpCas9	negative selection	7474492
5457245	5457268	9	-	27260156	MEWO	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.12311033632920002	[534]	[583,409,408]	-3	hSpCas9	negative selection	7474493
5463096	5463119	9	-	27260156	MEWO	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.2591481808957131	[284]	[307,335,310]	5	hSpCas9	negative selection	7474494
5462918	5462941	9	+	27260156	MEWO	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.09579969004138783	[482]	[570,413,480]	2	hSpCas9	negative selection	7538769
5456130	5456153	9	+	27260156	MEWO	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.009931991269224838	[1434]	[1669,1302,1143]	0	hSpCas9	negative selection	7538770
5456145	5456168	9	-	27260156	MEWO	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-3.776294128576829e-05	[264]	[279,229,239]	0	hSpCas9	negative selection	7538771
5457360	5457383	9	+	27260156	LNCAPCLONEFGC	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.12335228350760596	[1369]	[1189,1229,1725,1326]	2	hSpCas9	negative selection	7595743
5457245	5457268	9	-	27260156	LNCAPCLONEFGC	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.32319049918524484	[534]	[648,463,609,710]	5	hSpCas9	negative selection	7595744
5463096	5463119	9	-	27260156	LNCAPCLONEFGC	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.8967537230769029	[284]	[417,531,512,461]	9	hSpCas9	negative selection	7595745
5462918	5462941	9	+	27260156	LNCAPCLONEFGC	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.5135925302312059	[482]	[646,615,609,622]	7	hSpCas9	negative selection	7660020
5456130	5456153	9	+	27260156	LNCAPCLONEFGC	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.1812989055480969	[1434]	[1487,1223,1762,1478]	3	hSpCas9	negative selection	7660021
5456145	5456168	9	-	27260156	LNCAPCLONEFGC	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.1305796973109895	[264]	[144,179,198,353]	-2	hSpCas9	negative selection	7660022
5457360	5457383	9	+	27260156	PANC0327	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.20147092009449685	[1369]	[1428,1618,1262,1259]	3	hSpCas9	negative selection	7716994
5457245	5457268	9	-	27260156	PANC0327	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.39016463503734516	[534]	[529,635,720,594]	6	hSpCas9	negative selection	7716995
5463096	5463119	9	-	27260156	PANC0327	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	1.0562708946175987	[284]	[397,415,396,897]	9	hSpCas9	negative selection	7716996
5462918	5462941	9	+	27260156	PANC0327	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.09943403092842068	[482]	[395,308,625,521]	1	hSpCas9	negative selection	7781271
5456130	5456153	9	+	27260156	PANC0327	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.309450599208416	[1434]	[2042,1560,1190,1562]	4	hSpCas9	negative selection	7781272
5456145	5456168	9	-	27260156	PANC0327	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.496729859185882	[264]	[459,298,190,392]	7	hSpCas9	negative selection	7781273
5457360	5457383	9	+	27260156	NCIH2009	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.42795345114293837	[1369]	[2809,2372,2587]	6	hSpCas9	negative selection	7838245
5457245	5457268	9	-	27260156	NCIH2009	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.12728432680860297	[534]	[729,529,1175]	1	hSpCas9	negative selection	7838246
5463096	5463119	9	-	27260156	NCIH2009	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.7062449721235851	[284]	[748,678,538]	8	hSpCas9	negative selection	7838247
5462918	5462941	9	+	27260156	NCIH2009	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.8149212934597838	[482]	[1260,1244,1066]	9	hSpCas9	negative selection	7902522
5456130	5456153	9	+	27260156	NCIH2009	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.12396678332395017	[1434]	[2859,1919,1908]	1	hSpCas9	negative selection	7902523
5456145	5456168	9	-	27260156	NCIH2009	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.07020786903588105	[264]	[394,393,275]	-1	hSpCas9	negative selection	7902524
5457360	5457383	9	+	27260156	NCIH1373	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.22854289586599075	[1369]	[2554,1630,1458,440]	2	hSpCas9	negative selection	7959496
5457245	5457268	9	-	27260156	NCIH1373	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.22804027462877402	[534]	[1014,807,204,218]	2	hSpCas9	negative selection	7959497
5463096	5463119	9	-	27260156	NCIH1373	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.38447676405558256	[284]	[393,379,496,102]	4	hSpCas9	negative selection	7959498
5462918	5462941	9	+	27260156	NCIH1373	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.7500698042151619	[482]	[753,712,854,351]	7	hSpCas9	negative selection	8023773
5456130	5456153	9	+	27260156	NCIH1373	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.4788588145149497	[1434]	[2747,1434,2326,691]	5	hSpCas9	negative selection	8023774
5456145	5456168	9	-	27260156	NCIH1373	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.17628643827698143	[264]	[350,178,188,94]	-2	hSpCas9	negative selection	8023775
5457360	5457383	9	+	27260156	PATU8902	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.06413394193140376	[1369]	[2007,1512,1401,3354]	0	hSpCas9	negative selection	8080747
5457245	5457268	9	-	27260156	PATU8902	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.34071315678396547	[534]	[839,601,953,1425]	3	hSpCas9	negative selection	8080748
5463096	5463119	9	-	27260156	PATU8902	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	1.2811668719200024	[284]	[941,993,758,1242]	9	hSpCas9	negative selection	8080749
5462918	5462941	9	+	27260156	PATU8902	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.5494550524370769	[482]	[1070,1111,777,1026]	6	hSpCas9	negative selection	8145024
5456130	5456153	9	+	27260156	PATU8902	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.6267536575110391	[1434]	[2748,2874,2772,4131]	6	hSpCas9	negative selection	8145025
5456145	5456168	9	-	27260156	PATU8902	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.4892315236161254	[264]	[288,1323,242,257]	5	hSpCas9	negative selection	8145026
5457360	5457383	9	+	27260156	PANC1	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.13205612513561116	[1369]	[1297,1733,1000,1205]	2	hSpCas9	negative selection	8201998
5457245	5457268	9	-	27260156	PANC1	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.17480118739976785	[534]	[523,619,667,310]	2	hSpCas9	negative selection	8201999
5463096	5463119	9	-	27260156	PANC1	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6912887990085379	[284]	[358,472,436,332]	9	hSpCas9	negative selection	8202000
5462918	5462941	9	+	27260156	PANC1	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.2618190197513826	[482]	[506,545,449,488]	4	hSpCas9	negative selection	8266275
5456130	5456153	9	+	27260156	PANC1	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.20715350403443344	[1434]	[1533,1908,1380,1009]	3	hSpCas9	negative selection	8266276
5456145	5456168	9	-	27260156	PANC1	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.19976560417706224	[264]	[141,350,283,281]	3	hSpCas9	negative selection	8266277
5457360	5457383	9	+	27260156	PANC0813	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.32881865945587174	[1369]	[2402,1503,2225,1986]	5	hSpCas9	negative selection	8323249
5457245	5457268	9	-	27260156	PANC0813	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.08792262881087354	[534]	[685,1005,510,478]	1	hSpCas9	negative selection	8323250
5463096	5463119	9	-	27260156	PANC0813	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6954906748431486	[284]	[539,491,717,424]	9	hSpCas9	negative selection	8323251
5462918	5462941	9	+	27260156	PANC0813	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.2838914603570356	[482]	[695,386,819,850]	4	hSpCas9	negative selection	8387526
5456130	5456153	9	+	27260156	PANC0813	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.07022997843103695	[1434]	[1852,1740,2005,1499]	1	hSpCas9	negative selection	8387527
5456145	5456168	9	-	27260156	PANC0813	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.30507718597423195	[264]	[264,158,280,300]	-5	hSpCas9	negative selection	8387528
5457360	5457383	9	+	27260156	RDES	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.255637333858594	[1369]	[1555,1612,2047,2437]	4	hSpCas9	negative selection	8444500
5457245	5457268	9	-	27260156	RDES	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.36018785255963265	[534]	[532,776,760,1181]	6	hSpCas9	negative selection	8444501
5463096	5463119	9	-	27260156	RDES	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.9104885591312941	[284]	[577,522,503,894]	9	hSpCas9	negative selection	8444502
5462918	5462941	9	+	27260156	RDES	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.5072060655676007	[482]	[655,751,945,822]	7	hSpCas9	negative selection	8508777
5456130	5456153	9	+	27260156	RDES	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.32978253211781583	[1434]	[1848,1816,2255,2445]	5	hSpCas9	negative selection	8508778
5456145	5456168	9	-	27260156	RDES	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.02986460064223373	[264]	[220,312,360,370]	0	hSpCas9	negative selection	8508779
5457360	5457383	9	+	27260156	PC3	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.08378809005481447	[1369]	[899,1531,2328,1465]	2	hSpCas9	negative selection	8565751
5457245	5457268	9	-	27260156	PC3	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.020706861728860382	[534]	[324,498,967,521]	0	hSpCas9	negative selection	8565752
5463096	5463119	9	-	27260156	PC3	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.5175604128362261	[284]	[342,328,580,422]	9	hSpCas9	negative selection	8565753
5462918	5462941	9	+	27260156	PC3	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.1807971848549466	[482]	[268,435,1053,714]	4	hSpCas9	negative selection	8630028
5456130	5456153	9	+	27260156	PC3	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.07189111000936332	[1434]	[982,1215,2351,1904]	1	hSpCas9	negative selection	8630029
5456145	5456168	9	-	27260156	PC3	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.020888551357293506	[264]	[143,337,339,273]	0	hSpCas9	negative selection	8630030
5457360	5457383	9	+	27260156	PATU8988T	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.1621170422883147	[1369]	[1427,1295,1810,1357]	2	hSpCas9	negative selection	8687002
5457245	5457268	9	-	27260156	PATU8988T	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.06561606460390239	[534]	[326,691,525,444]	-1	hSpCas9	negative selection	8687003
5463096	5463119	9	-	27260156	PATU8988T	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6695931623615773	[284]	[467,353,303,635]	9	hSpCas9	negative selection	8687004
5462918	5462941	9	+	27260156	PATU8988T	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.5069561479002245	[482]	[991,540,578,518]	8	hSpCas9	negative selection	8751279
5456130	5456153	9	+	27260156	PATU8988T	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.1508012518435049	[1434]	[1518,1583,1703,1335]	2	hSpCas9	negative selection	8751280
5456145	5456168	9	-	27260156	PATU8988T	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.3766942935721068	[264]	[199,78,205,300]	-6	hSpCas9	negative selection	8751281
5457360	5457383	9	+	27260156	T47D	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.0772747962167224	[1369]	[1747,1493,1669,1844]	1	hSpCas9	negative selection	8808253
5457245	5457268	9	-	27260156	T47D	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.09641713314199235	[534]	[575,609,699,786]	2	hSpCas9	negative selection	8808254
5463096	5463119	9	-	27260156	T47D	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6949561541094562	[284]	[587,578,500,476]	9	hSpCas9	negative selection	8808255
5462918	5462941	9	+	27260156	T47D	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.27242058646751194	[482]	[678,608,638,801]	6	hSpCas9	negative selection	8872530
5456130	5456153	9	+	27260156	T47D	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.14036821564236757	[1434]	[1936,1785,1678,1979]	3	hSpCas9	negative selection	8872531
5456145	5456168	9	-	27260156	T47D	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.3108723330939548	[264]	[353,306,440,436]	6	hSpCas9	negative selection	8872532
5457360	5457383	9	+	27260156	SU8686	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.22964986298682488	[1369]	[1453,1629,1666,1625]	4	hSpCas9	negative selection	8929504
5457245	5457268	9	-	27260156	SU8686	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.012960913035104576	[534]	[485,444,564,636]	0	hSpCas9	negative selection	8929505
5463096	5463119	9	-	27260156	SU8686	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.5011793550516354	[284]	[362,385,369,498]	8	hSpCas9	negative selection	8929506
5462918	5462941	9	+	27260156	SU8686	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.17580812542529323	[482]	[466,395,683,663]	3	hSpCas9	negative selection	8993781
5456130	5456153	9	+	27260156	SU8686	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.3323520874768835	[1434]	[1599,1576,2047,2020]	5	hSpCas9	negative selection	8993782
5456145	5456168	9	-	27260156	SU8686	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.06373119020937867	[264]	[175,371,239,311]	1	hSpCas9	negative selection	8993783
5457360	5457383	9	+	27260156	SKES1	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	0.056846478082441365	[1369]	[1285,1969,1302,1188]	1	hSpCas9	negative selection	9050755
5457245	5457268	9	-	27260156	SKES1	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.1820675423552362	[534]	[606,949,462,456]	4	hSpCas9	negative selection	9050756
5463096	5463119	9	-	27260156	SKES1	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6900980202354211	[284]	[465,674,461,275]	9	hSpCas9	negative selection	9050757
5462918	5462941	9	+	27260156	SKES1	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.5164224073057853	[482]	[987,732,554,539]	9	hSpCas9	negative selection	9115032
5456130	5456153	9	+	27260156	SKES1	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.010702901140407173	[1434]	[1675,1489,1438,1213]	0	hSpCas9	negative selection	9115033
5456145	5456168	9	-	27260156	SKES1	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	-0.1263096958729878	[264]	[246,357,267,121]	-3	hSpCas9	negative selection	9115034
5457360	5457383	9	+	27260156	TOV112D	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-0.03106334906298458	[1369]	[1312,1629,1169,1324]	0	hSpCas9	negative selection	9172006
5457245	5457268	9	-	27260156	TOV112D	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	-0.13812407638674518	[534]	[566,476,487,420]	-3	hSpCas9	negative selection	9172007
5463096	5463119	9	-	27260156	TOV112D	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.4430404643053048	[284]	[331,719,241,335]	7	hSpCas9	negative selection	9172008
5462918	5462941	9	+	27260156	TOV112D	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.5237849507301742	[482]	[592,897,597,731]	8	hSpCas9	negative selection	9236283
5456130	5456153	9	+	27260156	TOV112D	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.05227902228090775	[1434]	[1414,1954,1546,1158]	1	hSpCas9	negative selection	9236284
5456145	5456168	9	-	27260156	TOV112D	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.23484924887349956	[264]	[461,343,215,248]	4	hSpCas9	negative selection	9236285
5457360	5457383	9	+	27260156	TC71	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-0.02918637878444641	[1369]	[1541,1340,1445,1423]	0	hSpCas9	negative selection	9293257
5457245	5457268	9	-	27260156	TC71	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.08656614385091027	[534]	[550,694,581,609]	2	hSpCas9	negative selection	9293258
5463096	5463119	9	-	27260156	TC71	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.7686006435559395	[284]	[489,495,461,643]	9	hSpCas9	negative selection	9293259
5462918	5462941	9	+	27260156	TC71	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	-0.03575736022451345	[482]	[586,525,420,485]	-1	hSpCas9	negative selection	9357534
5456130	5456153	9	+	27260156	TC71	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.01397826757954057	[1434]	[1698,1280,1607,1623]	0	hSpCas9	negative selection	9357535
5456145	5456168	9	-	27260156	TC71	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.21397661449871286	[264]	[331,352,280,354]	5	hSpCas9	negative selection	9357536
5457360	5457383	9	+	27260156	TC32	viability	TACCGCTGCATGATCAGCTATGG	CD274	ENSG00000120217	-0.049874139814754415	[1369]	[1113,819,1706,1536]	-1	hSpCas9	negative selection	9414508
5457245	5457268	9	-	27260156	TC32	viability	AGCTACTATGCTGAACCTTCAGG	CD274	ENSG00000120217	0.10938160008244696	[534]	[779,221,626,618]	2	hSpCas9	negative selection	9414509
5463096	5463119	9	-	27260156	TC32	viability	GGATGACCAATTCAGCTGTATGG	CD274	ENSG00000120217	0.6944778099253014	[284]	[382,358,467,543]	9	hSpCas9	negative selection	9414510
5462918	5462941	9	+	27260156	TC32	viability	ACCCCAAGGCCGAAGTCATCTGG	CD274	ENSG00000120217	0.48438307570937894	[482]	[511,700,664,613]	7	hSpCas9	negative selection	9478785
5456130	5456153	9	+	27260156	TC32	viability	TCTTTATATTCATGACCTACTGG	CD274	ENSG00000120217	0.2690128744382496	[1434]	[1562,1313,2058,1666]	5	hSpCas9	negative selection	9478786
5456145	5456168	9	-	27260156	TC32	viability	ACCGTTCAGCAAATGCCAGTAGG	CD274	ENSG00000120217	0.050952757929332515	[264]	[176,289,226,316]	0	hSpCas9	negative selection	9478787
5457080	5457103	9	+	27869803	HPAFII	viability after 27 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-1.0912785728756127	[55]	[3,21,NaN]	-6	hSpCas9	negative selection	9606204
5465504	5465527	9	-	27869803	HPAFII	viability after 27 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.6062747921035424	[157]	[96,150,NaN]	5	hSpCas9	negative selection	9606205
5465566	5465589	9	-	27869803	HPAFII	viability after 27 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.6763957664196532	[387]	[523,160,NaN]	5	hSpCas9	negative selection	9606206
5457080	5457103	9	+	27869803	HPAFII	viability after 15 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-0.2408043186356248	[55]	[45,53,NaN]	-3	hSpCas9	negative selection	9688653
5465504	5465527	9	-	27869803	HPAFII	viability after 15 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.7860793887391653	[157]	[425,209,NaN]	8	hSpCas9	negative selection	9688654
5465566	5465589	9	-	27869803	HPAFII	viability after 15 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.42971350346542203	[387]	[1033,267,NaN]	5	hSpCas9	negative selection	9688655
5457080	5457103	9	+	27869803	ASPC1	viability after 36 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-1.161095922600242	[148]	[17,37,14]	-8	hSpCas9	negative selection	9771102
5465504	5465527	9	-	27869803	ASPC1	viability after 36 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-1.3332035510936524	[501]	[84,66,59]	-8	hSpCas9	negative selection	9771103
5465566	5465589	9	-	27869803	ASPC1	viability after 36 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.23417113390107902	[1175]	[283,617,509]	2	hSpCas9	negative selection	9771104
5457080	5457103	9	+	27869803	PATU8988S	viability after 35 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	0.43163575751736016	[137]	[58,90,NaN]	5	hSpCas9	negative selection	9853551
5465504	5465527	9	-	27869803	PATU8988S	viability after 35 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.4329855623993109	[398]	[192,240,NaN]	5	hSpCas9	negative selection	9853552
5465566	5465589	9	-	27869803	PATU8988S	viability after 35 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.4793823238754944	[861]	[486,480,NaN]	5	hSpCas9	negative selection	9853553
5457080	5457103	9	+	27869803	PATU8988S	viability after 31 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-0.10176353050017317	[137]	[45,57,NaN]	-1	hSpCas9	negative selection	9936000
5465504	5465527	9	-	27869803	PATU8988S	viability after 31 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.4748203782034055	[398]	[155,303,NaN]	6	hSpCas9	negative selection	9936001
5465566	5465589	9	-	27869803	PATU8988S	viability after 31 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.6143022856766513	[861]	[563,477,NaN]	7	hSpCas9	negative selection	9936002
5457080	5457103	9	+	27869803	HPAFII	viability after 35 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-1.815321607589425	[55]	[0,15,NaN]	-7	hSpCas9	negative selection	10018449
5465504	5465527	9	-	27869803	HPAFII	viability after 35 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.5308218940441709	[157]	[60,176,NaN]	3	hSpCas9	negative selection	10018450
5465566	5465589	9	-	27869803	HPAFII	viability after 35 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.6845121028156631	[387]	[508,97,NaN]	4	hSpCas9	negative selection	10018451
5457080	5457103	9	+	27869803	HPAFII	viability after 31 days	ATTTACTGTCACGGTTCCCAAGG	CD274	ENSG00000120217	-1.302366839407008	[55]	[6,18,NaN]	-7	hSpCas9	negative selection	10100898
5465504	5465527	9	-	27869803	HPAFII	viability after 31 days	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	1.1579578722904622	[157]	[138,261,NaN]	8	hSpCas9	negative selection	10100899
5465566	5465589	9	-	27869803	HPAFII	viability after 31 days	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.43858830683423533	[387]	[453,121,NaN]	3	hSpCas9	negative selection	10100900
5465566	5465589	9	-	28162770	P31FUJ	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.29599358554597655	[645]	[931]	3	hSpCas9	negative selection	10129257
5463085	5463108	9	-	28162770	P31FUJ	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.8727635512315557	[190]	[410]	8	hSpCas9	negative selection	10129258
5462904	5462927	9	+	28162770	P31FUJ	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.16867186699466297	[505]	[528]	-2	hSpCas9	negative selection	10129259
5465549	5465572	9	+	28162770	P31FUJ	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	0.17462211075459008	[189]	[251]	1	hSpCas9	negative selection	10129260
5462892	5462915	9	+	28162770	P31FUJ	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	1.2146567725568422	[21]	[59]	9	hSpCas9	negative selection	10129261
5462975	5462998	9	-	28162770	P31FUJ	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	-0.048980976858988945	[286]	[325]	0	hSpCas9	negative selection	10129262
5462947	5462970	9	+	28162770	P31FUJ	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	-0.14225044670675385	[246]	[262]	-1	hSpCas9	negative selection	10129263
5463100	5463123	9	+	28162770	P31FUJ	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.03706423490184052	[315]	[380]	0	hSpCas9	negative selection	10129264
5465504	5465527	9	-	28162770	P31FUJ	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.4775077577507747	[873]	[1429]	5	hSpCas9	negative selection	10129265
5463020	5463043	9	-	28162770	P31FUJ	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.8688778713217358	[492]	[1057]	8	hSpCas9	negative selection	10129266
5465566	5465589	9	-	28162770	TF1	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	NaN	[NaN]	[418]	1	hSpCas9	negative selection	10298623
5463085	5463108	9	-	28162770	TF1	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	NaN	[NaN]	[277]	1	hSpCas9	negative selection	10298624
5462904	5462927	9	+	28162770	TF1	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	NaN	[NaN]	[331]	1	hSpCas9	negative selection	10298625
5465549	5465572	9	+	28162770	TF1	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	NaN	[NaN]	[327]	1	hSpCas9	negative selection	10298626
5462892	5462915	9	+	28162770	TF1	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10298627
5462975	5462998	9	-	28162770	TF1	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	NaN	[NaN]	[265]	1	hSpCas9	negative selection	10298628
5462947	5462970	9	+	28162770	TF1	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	NaN	[NaN]	[127]	1	hSpCas9	negative selection	10298629
5463100	5463123	9	+	28162770	TF1	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10298630
5465504	5465527	9	-	28162770	TF1	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	NaN	[NaN]	[941]	1	hSpCas9	negative selection	10298631
5463020	5463043	9	-	28162770	TF1	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	NaN	[NaN]	[403]	1	hSpCas9	negative selection	10298632
5465566	5465589	9	-	28162770	SKM1	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.17004954886250356	[181]	[361]	1	hSpCas9	negative selection	10467989
5463085	5463108	9	-	28162770	SKM1	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.4873263600857235	[22]	[56]	5	hSpCas9	negative selection	10467990
5462904	5462927	9	+	28162770	SKM1	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.03881308709515374	[85]	[147]	0	hSpCas9	negative selection	10467991
5465549	5465572	9	+	28162770	SKM1	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	1.2013308058086183	[45]	[186]	9	hSpCas9	negative selection	10467992
5462892	5462915	9	+	28162770	SKM1	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	1.42592581542158	[7]	[37]	9	hSpCas9	negative selection	10467993
5462975	5462998	9	-	28162770	SKM1	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	1.0447317711145303	[50]	[185]	8	hSpCas9	negative selection	10467994
5462947	5462970	9	+	28162770	SKM1	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.7132077675020511	[58]	[170]	7	hSpCas9	negative selection	10467995
5463100	5463123	9	+	28162770	SKM1	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.8218544917527193	[63]	[199]	7	hSpCas9	negative selection	10467996
5465504	5465527	9	-	28162770	SKM1	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.2970054821105401	[156]	[340]	3	hSpCas9	negative selection	10467997
5463020	5463043	9	-	28162770	SKM1	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.9458248598489613	[110]	[377]	8	hSpCas9	negative selection	10467998
5465566	5465589	9	-	28162770	SKM1	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.17004954886250356	[181]	[361]	1	hSpCas9	negative selection	10637355
5463085	5463108	9	-	28162770	SKM1	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.4873263600857235	[22]	[56]	5	hSpCas9	negative selection	10637356
5462904	5462927	9	+	28162770	SKM1	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.03881308709515374	[85]	[147]	0	hSpCas9	negative selection	10637357
5465549	5465572	9	+	28162770	SKM1	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	1.2013308058086183	[45]	[186]	9	hSpCas9	negative selection	10637358
5462892	5462915	9	+	28162770	SKM1	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	1.42592581542158	[7]	[37]	9	hSpCas9	negative selection	10637359
5462975	5462998	9	-	28162770	SKM1	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	1.0447317711145303	[50]	[185]	8	hSpCas9	negative selection	10637360
5462947	5462970	9	+	28162770	SKM1	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.7132077675020511	[58]	[170]	7	hSpCas9	negative selection	10637361
5463100	5463123	9	+	28162770	SKM1	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.8218544917527193	[63]	[199]	7	hSpCas9	negative selection	10637362
5465504	5465527	9	-	28162770	SKM1	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.2970054821105401	[156]	[340]	3	hSpCas9	negative selection	10637363
5463020	5463043	9	-	28162770	SKM1	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.9458248598489613	[110]	[377]	8	hSpCas9	negative selection	10637364
5465566	5465589	9	-	28162770	PL21	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.035603842477429426	[667]	[297]	0	hSpCas9	negative selection	10806721
5463085	5463108	9	-	28162770	PL21	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.7851021152104763	[103]	[77]	6	hSpCas9	negative selection	10806722
5462904	5462927	9	+	28162770	PL21	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.3772297369096058	[378]	[126]	-3	hSpCas9	negative selection	10806723
5465549	5465572	9	+	28162770	PL21	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	-0.1362880500931572	[249]	[98]	-1	hSpCas9	negative selection	10806724
5462892	5462915	9	+	28162770	PL21	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	1.2001396144893202	[27]	[27]	8	hSpCas9	negative selection	10806725
5462975	5462998	9	-	28162770	PL21	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	0.9458983271135323	[228]	[191]	7	hSpCas9	negative selection	10806726
5462947	5462970	9	+	28162770	PL21	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	-0.24947103333694984	[182]	[66]	-2	hSpCas9	negative selection	10806727
5463100	5463123	9	+	28162770	PL21	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	-0.017451820583306618	[199]	[85]	0	hSpCas9	negative selection	10806728
5465504	5465527	9	-	28162770	PL21	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.299149620320486	[548]	[293]	2	hSpCas9	negative selection	10806729
5463020	5463043	9	-	28162770	PL21	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	-0.25657591603939434	[397]	[144]	-2	hSpCas9	negative selection	10806730
5465566	5465589	9	-	28162770	P31FUJ	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.29599358554597655	[645]	[931]	3	hSpCas9	negative selection	10976087
5463085	5463108	9	-	28162770	P31FUJ	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.8727635512315557	[190]	[410]	8	hSpCas9	negative selection	10976088
5462904	5462927	9	+	28162770	P31FUJ	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.16867186699466297	[505]	[528]	-2	hSpCas9	negative selection	10976089
5465549	5465572	9	+	28162770	P31FUJ	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	0.17462211075459008	[189]	[251]	1	hSpCas9	negative selection	10976090
5462892	5462915	9	+	28162770	P31FUJ	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	1.2146567725568422	[21]	[59]	9	hSpCas9	negative selection	10976091
5462975	5462998	9	-	28162770	P31FUJ	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	-0.048980976858988945	[286]	[325]	0	hSpCas9	negative selection	10976092
5462947	5462970	9	+	28162770	P31FUJ	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	-0.14225044670675385	[246]	[262]	-1	hSpCas9	negative selection	10976093
5463100	5463123	9	+	28162770	P31FUJ	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.03706423490184052	[315]	[380]	0	hSpCas9	negative selection	10976094
5465504	5465527	9	-	28162770	P31FUJ	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.4775077577507747	[873]	[1429]	5	hSpCas9	negative selection	10976095
5463020	5463043	9	-	28162770	P31FUJ	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.8688778713217358	[492]	[1057]	8	hSpCas9	negative selection	10976096
5465566	5465589	9	-	28162770	OCIAML5	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.18954381930737418	[392]	[808]	1	hSpCas9	negative selection	11145453
5463085	5463108	9	-	28162770	OCIAML5	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	-0.45613789453285797	[132]	[174]	-3	hSpCas9	negative selection	11145454
5462904	5462927	9	+	28162770	OCIAML5	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.3539473300905981	[193]	[273]	-3	hSpCas9	negative selection	11145455
5465549	5465572	9	+	28162770	OCIAML5	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	0.4312402299960578	[105]	[257]	4	hSpCas9	negative selection	11145456
5462892	5462915	9	+	28162770	OCIAML5	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	-0.4664128783662477	[61]	[80]	-3	hSpCas9	negative selection	11145457
5462975	5462998	9	-	28162770	OCIAML5	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	0.2984931057113843	[149]	[332]	2	hSpCas9	negative selection	11145458
5462947	5462970	9	+	28162770	OCIAML5	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.35700068609387015	[201]	[466]	3	hSpCas9	negative selection	11145459
5463100	5463123	9	+	28162770	OCIAML5	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.49188783035336425	[155]	[395]	4	hSpCas9	negative selection	11145460
5465504	5465527	9	-	28162770	OCIAML5	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.6274836899695755	[368]	[1028]	5	hSpCas9	negative selection	11145461
5463020	5463043	9	-	28162770	OCIAML5	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.5074758158231434	[264]	[679]	4	hSpCas9	negative selection	11145462
5465566	5465589	9	-	28162770	EOL1	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.7319026936281388	[1191]	[1042]	6	hSpCas9	negative selection	11314819
5463085	5463108	9	-	28162770	EOL1	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.4986219561489543	[132]	[98]	4	hSpCas9	negative selection	11314820
5462904	5462927	9	+	28162770	EOL1	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	0.35136243862573235	[731]	[491]	3	hSpCas9	negative selection	11314821
5465549	5465572	9	+	28162770	EOL1	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	-0.9530782295327892	[304]	[82]	-6	hSpCas9	negative selection	11314822
5462892	5462915	9	+	28162770	EOL1	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	-1.7245450665703372	[68]	[10]	-8	hSpCas9	negative selection	11314823
5462975	5462998	9	-	28162770	EOL1	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	1.421018247274268	[408]	[576]	9	hSpCas9	negative selection	11314824
5462947	5462970	9	+	28162770	EOL1	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	1.0066488517854282	[221]	[234]	8	hSpCas9	negative selection	11314825
5463100	5463123	9	+	28162770	EOL1	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.07463238728488482	[300]	[166]	0	hSpCas9	negative selection	11314826
5465504	5465527	9	-	28162770	EOL1	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.6791612315561657	[779]	[657]	6	hSpCas9	negative selection	11314827
5463020	5463043	9	-	28162770	EOL1	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.7153709697382507	[488]	[422]	6	hSpCas9	negative selection	11314828
5465566	5465589	9	-	28162770	MOLM13	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.646659873853612	[1083]	[1226]	5	hSpCas9	negative selection	11484185
5463085	5463108	9	-	28162770	MOLM13	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.1403147235160744	[255]	[203]	1	hSpCas9	negative selection	11484186
5462904	5462927	9	+	28162770	MOLM13	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	0.24769117362104276	[437]	[375]	1	hSpCas9	negative selection	11484187
5465549	5465572	9	+	28162770	MOLM13	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	0.8121055436337257	[333]	[423]	6	hSpCas9	negative selection	11484188
5462892	5462915	9	+	28162770	MOLM13	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.2091551131444107	[66]	[55]	1	hSpCas9	negative selection	11484189
5462975	5462998	9	-	28162770	MOLM13	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	1.7958580785892406	[285]	[717]	9	hSpCas9	negative selection	11484190
5462947	5462970	9	+	28162770	MOLM13	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.12853148053084026	[228]	[180]	0	hSpCas9	negative selection	11484191
5463100	5463123	9	+	28162770	MOLM13	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.9865271228377791	[318]	[456]	7	hSpCas9	negative selection	11484192
5465504	5465527	9	-	28162770	MOLM13	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.23759176212278454	[731]	[623]	1	hSpCas9	negative selection	11484193
5463020	5463043	9	-	28162770	MOLM13	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	-0.20734722286992113	[609]	[381]	-1	hSpCas9	negative selection	11484194
5465566	5465589	9	-	28162770	HEL	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-1.6112666080323113	[891]	[186]	-7	hSpCas9	negative selection	11653551
5463085	5463108	9	-	28162770	HEL	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	-2.020226180722072	[170]	[26]	-8	hSpCas9	negative selection	11653552
5462904	5462927	9	+	28162770	HEL	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-1.3025840753793287	[465]	[120]	-6	hSpCas9	negative selection	11653553
5465549	5465572	9	+	28162770	HEL	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	1.4581851664115086	[253]	[446]	9	hSpCas9	negative selection	11653554
5462892	5462915	9	+	28162770	HEL	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	-0.03103293567865517	[66]	[41]	0	hSpCas9	negative selection	11653555
5462975	5462998	9	-	28162770	HEL	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	-0.15081029053221667	[337]	[194]	-1	hSpCas9	negative selection	11653556
5462947	5462970	9	+	28162770	HEL	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	-0.7766376030028243	[221]	[82]	-5	hSpCas9	negative selection	11653557
5463100	5463123	9	+	28162770	HEL	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	-0.3148259016792464	[267]	[137]	-2	hSpCas9	negative selection	11653558
5465504	5465527	9	-	28162770	HEL	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	-1.2062234108508234	[597]	[165]	-6	hSpCas9	negative selection	11653559
5463020	5463043	9	-	28162770	HEL	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.3485938936265327	[449]	[366]	3	hSpCas9	negative selection	11653560
5465566	5465589	9	-	28162770	MV411	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.42211608219572216	[605]	[683]	4	hSpCas9	negative selection	11822917
5463085	5463108	9	-	28162770	MV411	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.6880101421687566	[97]	[132]	6	hSpCas9	negative selection	11822918
5462904	5462927	9	+	28162770	MV411	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	-0.2910599053219942	[442]	[304]	-2	hSpCas9	negative selection	11822919
5465549	5465572	9	+	28162770	MV411	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	-0.20236536665674515	[223]	[163]	-1	hSpCas9	negative selection	11822920
5462892	5462915	9	+	28162770	MV411	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	2.7770570176601566	[30]	[178]	9	hSpCas9	negative selection	11822921
5462975	5462998	9	-	28162770	MV411	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	0.4085923425973556	[219]	[245]	3	hSpCas9	negative selection	11822922
5462947	5462970	9	+	28162770	MV411	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.4079022229760214	[169]	[189]	3	hSpCas9	negative selection	11822923
5463100	5463123	9	+	28162770	MV411	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.20561737508814837	[209]	[203]	1	hSpCas9	negative selection	11822924
5465504	5465527	9	-	28162770	MV411	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.44616658087246575	[561]	[644]	4	hSpCas9	negative selection	11822925
5463020	5463043	9	-	28162770	MV411	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.4117648626084205	[372]	[417]	3	hSpCas9	negative selection	11822926
5465566	5465589	9	-	28162770	MONOMAC1	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.33347786963922577	[494]	[714]	3	hSpCas9	negative selection	11992283
5463085	5463108	9	-	28162770	MONOMAC1	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.7423003710338222	[84]	[162]	7	hSpCas9	negative selection	11992284
5462904	5462927	9	+	28162770	MONOMAC1	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	0.2780911020556196	[240]	[334]	3	hSpCas9	negative selection	11992285
5465549	5465572	9	+	28162770	MONOMAC1	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	0.5153049601378301	[129]	[212]	5	hSpCas9	negative selection	11992286
5462892	5462915	9	+	28162770	MONOMAC1	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	-0.5955862235498288	[28]	[21]	-5	hSpCas9	negative selection	11992287
5462975	5462998	9	-	28162770	MONOMAC1	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	0.8215788311077934	[153]	[311]	7	hSpCas9	negative selection	11992288
5462947	5462970	9	+	28162770	MONOMAC1	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.45503984952013954	[97]	[153]	4	hSpCas9	negative selection	11992289
5463100	5463123	9	+	28162770	MONOMAC1	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	-0.2073787912810127	[139]	[138]	-2	hSpCas9	negative selection	11992290
5465504	5465527	9	-	28162770	MONOMAC1	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.7694335293752519	[369]	[722]	7	hSpCas9	negative selection	11992291
5463020	5463043	9	-	28162770	MONOMAC1	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.2936457055621833	[273]	[384]	3	hSpCas9	negative selection	11992292
5465566	5465589	9	-	28162770	OCIAML2	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	0.21315041169691007	[133]	[860]	2	hSpCas9	negative selection	12161649
5463085	5463108	9	-	28162770	OCIAML2	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	0.1753621088765545	[26]	[168]	1	hSpCas9	negative selection	12161650
5462904	5462927	9	+	28162770	OCIAML2	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	0.30466388758314433	[51]	[355]	3	hSpCas9	negative selection	12161651
5465549	5465572	9	+	28162770	OCIAML2	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	0.47154952036949643	[34]	[268]	4	hSpCas9	negative selection	12161652
5462892	5462915	9	+	28162770	OCIAML2	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	0.7772976882014242	[7]	[75]	7	hSpCas9	negative selection	12161653
5462975	5462998	9	-	28162770	OCIAML2	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	1.3909866906019168	[40]	[595]	9	hSpCas9	negative selection	12161654
5462947	5462970	9	+	28162770	OCIAML2	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	0.3639465655504674	[29]	[213]	3	hSpCas9	negative selection	12161655
5463100	5463123	9	+	28162770	OCIAML2	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.721388947050768	[35]	[328]	7	hSpCas9	negative selection	12161656
5465504	5465527	9	-	28162770	OCIAML2	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.5077833125496927	[100]	[795]	5	hSpCas9	negative selection	12161657
5463020	5463043	9	-	28162770	OCIAML2	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.5382483261042914	[80]	[651]	5	hSpCas9	negative selection	12161658
5465566	5465589	9	-	28162770	OCIAML3	viability	TGAATGTCAGTGCTACACCAAGG	CD274	ENSG00000120217	-0.07760942608607824	[157]	[451]	0	hSpCas9	negative selection	12331015
5463085	5463108	9	-	28162770	OCIAML3	viability	TCAGCTGTATGGTTTTCCTCAGG	CD274	ENSG00000120217	-0.9863250631029234	[62]	[95]	-6	hSpCas9	negative selection	12331016
5462904	5462927	9	+	28162770	OCIAML3	viability	TCAGGCTGAGGGCTACCCCAAGG	CD274	ENSG00000120217	0.20682415815210675	[94]	[330]	2	hSpCas9	negative selection	12331017
5465549	5465572	9	+	28162770	OCIAML3	viability	GGAGCCATCTTATTATGCCTTGG	CD274	ENSG00000120217	-0.0746334812305838	[44]	[128]	0	hSpCas9	negative selection	12331018
5462892	5462915	9	+	28162770	OCIAML3	viability	TGAACTGACATGTCAGGCTGAGG	CD274	ENSG00000120217	-2.272079545436801	[7]	[4]	-8	hSpCas9	negative selection	12331019
5462975	5462998	9	-	28162770	OCIAML3	viability	TCTCTTGGAATTGGTGGTGGTGG	CD274	ENSG00000120217	1.0550851978167086	[54]	[344]	8	hSpCas9	negative selection	12331020
5462947	5462970	9	+	28162770	OCIAML3	viability	AGTGACCATCAAGTCCTGAGTGG	CD274	ENSG00000120217	-0.7195385224080221	[53]	[98]	-5	hSpCas9	negative selection	12331021
5463100	5463123	9	+	28162770	OCIAML3	viability	ACAGCTGAATTGGTCATCCCAGG	CD274	ENSG00000120217	0.8415772363587664	[60]	[329]	7	hSpCas9	negative selection	12331022
5465504	5465527	9	-	28162770	OCIAML3	viability	TCATTTGGAGGATGTGCCAGAGG	CD274	ENSG00000120217	0.4481618139197765	[176]	[728]	4	hSpCas9	negative selection	12331023
5463020	5463043	9	-	28162770	OCIAML3	viability	TGTGTTGATTCTCAGTGTGCTGG	CD274	ENSG00000120217	0.9582578225775453	[118]	[697]	8	hSpCas9	negative selection	12331024