Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8476
• Symbol:CDC42BPA
• Description:CDC42 binding protein kinase alpha

DataSource: http://genomecrispr.dkfz.de/#!/results/CDC42BPA

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
227213135	227213158	1	-	26472758	Jiyoye	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	-0.17319984971963098	[156]	[104]	-1	hSpCas9	negative selection	28068
227040153	227040176	1	+	26472758	Jiyoye	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	-4.007862117772971	[63]	[2]	-9	hSpCas9	negative selection	28069
227147455	227147478	1	-	26472758	Jiyoye	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	0.6381809331470295	[166]	[195]	4	hSpCas9	negative selection	28070
227074337	227074360	1	-	26472758	Jiyoye	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.9531437506111659	[99]	[145]	6	hSpCas9	negative selection	28071
227034749	227034772	1	-	26472758	Jiyoye	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.33295749173901595	[151]	[90]	-2	hSpCas9	negative selection	28072
227028710	227028733	1	-	26472758	Jiyoye	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	6.361371691892748	[0]	[61]	9	hSpCas9	negative selection	28073
227254063	227254086	1	-	26472758	Jiyoye	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	1.4990978709469127	[37]	[80]	8	hSpCas9	negative selection	28074
227112320	227112343	1	-	26472758	Jiyoye	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	-0.44236948125003916	[372]	[206]	-3	hSpCas9	negative selection	28075
227091975	227091998	1	-	26472758	Jiyoye	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	0.5948023846816446	[35]	[40]	4	hSpCas9	negative selection	28076
227047978	227048001	1	+	26472758	Jiyoye	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	-0.21431299524039682	[219]	[142]	-1	hSpCas9	negative selection	28077
227213135	227213158	1	-	26472758	KBM7	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.7596535678068908	[630,485]	[518,370]	8	hSpCas9	negative selection	219186
227040153	227040176	1	+	26472758	KBM7	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	0.7898357968206238	[51,32]	[6,57]	8	hSpCas9	negative selection	219187
227147455	227147478	1	-	26472758	KBM7	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	1.019329122987711	[895,917]	[1016,737]	9	hSpCas9	negative selection	219188
227074337	227074360	1	-	26472758	KBM7	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.8263532559976747	[450,340]	[353,302]	8	hSpCas9	negative selection	219189
227034749	227034772	1	-	26472758	KBM7	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.08449994813978223	[832,757]	[375,331]	-1	hSpCas9	negative selection	219190
227028710	227028733	1	-	26472758	KBM7	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	-0.015298425767356516	[229,140]	[110,60]	0	hSpCas9	negative selection	219191
227254063	227254086	1	-	26472758	KBM7	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.3897351392264192	[518,364]	[263,272]	4	hSpCas9	negative selection	219192
227112320	227112343	1	-	26472758	KBM7	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.1564134455488949	[900,759]	[545,332]	1	hSpCas9	negative selection	219193
227091975	227091998	1	-	26472758	KBM7	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	0.06477645597700488	[258,218]	[67,160]	0	hSpCas9	negative selection	219194
227047978	227048001	1	+	26472758	KBM7	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.2956399115686551	[937,933]	[387,680]	3	hSpCas9	negative selection	219195
227213135	227213158	1	-	26472758	Raji	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.5527946836959622	[234]	[79]	5	hSpCas9	negative selection	410304
227040153	227040176	1	+	26472758	Raji	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	-0.21454455951376294	[24]	[4]	-2	hSpCas9	negative selection	410305
227147455	227147478	1	-	26472758	Raji	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	0.7344715117674322	[359]	[138]	7	hSpCas9	negative selection	410306
227074337	227074360	1	-	26472758	Raji	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.45530683879390654	[131]	[41]	4	hSpCas9	negative selection	410307
227034749	227034772	1	-	26472758	Raji	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	0.44138446256153685	[237]	[74]	4	hSpCas9	negative selection	410308
227028710	227028733	1	-	26472758	Raji	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	2.029381023372326	[37]	[35]	9	hSpCas9	negative selection	410309
227254063	227254086	1	-	26472758	Raji	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	-0.7584311172320032	[276]	[37]	-5	hSpCas9	negative selection	410310
227112320	227112343	1	-	26472758	Raji	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.5161072607202412	[457]	[151]	5	hSpCas9	negative selection	410311
227091975	227091998	1	-	26472758	Raji	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	1.4205414206332299	[65]	[40]	9	hSpCas9	negative selection	410312
227047978	227048001	1	+	26472758	Raji	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	-0.4887713802177611	[646]	[106]	-4	hSpCas9	negative selection	410313
227213135	227213158	1	-	26472758	K562	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.41178543450899996	[438]	[492]	3	hSpCas9	negative selection	601422
227040153	227040176	1	+	26472758	K562	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	1.1603544628779723	[52]	[99]	8	hSpCas9	negative selection	601423
227147455	227147478	1	-	26472758	K562	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	0.7786066611544771	[693]	[1004]	6	hSpCas9	negative selection	601424
227074337	227074360	1	-	26472758	K562	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-0.29820682649724917	[318]	[218]	-2	hSpCas9	negative selection	601425
227034749	227034772	1	-	26472758	K562	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-1.3889841281124626	[635]	[204]	-6	hSpCas9	negative selection	601426
227028710	227028733	1	-	26472758	K562	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	-1.170618771612397	[119]	[44]	-6	hSpCas9	negative selection	601427
227254063	227254086	1	-	26472758	K562	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.12164634554515132	[379]	[348]	0	hSpCas9	negative selection	601428
227112320	227112343	1	-	26472758	K562	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.6515365636490527	[821]	[1089]	5	hSpCas9	negative selection	601429
227091975	227091998	1	-	26472758	K562	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	1.0238195881530499	[200]	[344]	8	hSpCas9	negative selection	601430
227047978	227048001	1	+	26472758	K562	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	-0.46913547988970705	[814]	[496]	-3	hSpCas9	negative selection	601431
227112375	227112398	1	-	26627737	DLD1	viability	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.8018189186752354	[410]	[251,289,144]	7	hSpCas9	negative selection	769440
227112742	227112765	1	-	26627737	DLD1	viability	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.2985359648846369	[423]	[137,158,187]	3	hSpCas9	negative selection	769441
227139704	227139727	1	-	26627737	DLD1	viability	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.08632871536397035	[334]	[95,84,145]	0	hSpCas9	negative selection	769442
227145700	227145723	1	+	26627737	DLD1	viability	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-1.013623271892179	[241]	[50,12,45]	-7	hSpCas9	negative selection	769443
227147489	227147512	1	-	26627737	DLD1	viability	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	1.4198993492348013	[179]	[141,228,92]	9	hSpCas9	negative selection	769444
227317115	227317138	1	-	26627737	DLD1	viability	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	-0.13538624138027905	[328]	[130,105,50]	-1	hSpCas9	negative selection	769445
227112375	227112398	1	-	26627737	GBM cells	viability after 5 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.3774971906602296	[482]	[406,265]	6	hSpCas9	negative selection	851755
227112742	227112765	1	-	26627737	GBM cells	viability after 5 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.11454161817206576	[396]	[239,220]	1	hSpCas9	negative selection	851756
227139704	227139727	1	-	26627737	GBM cells	viability after 5 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.4336216048271456	[184]	[135,131]	6	hSpCas9	negative selection	851757
227145700	227145723	1	+	26627737	GBM cells	viability after 5 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-1.0092936491948237	[136]	[43,28]	-9	hSpCas9	negative selection	851758
227147489	227147512	1	-	26627737	GBM cells	viability after 5 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.097459554267766	[243]	[108,170]	1	hSpCas9	negative selection	851759
227317115	227317138	1	-	26627737	GBM cells	viability after 5 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.15229811068576016	[124]	[54,93]	2	hSpCas9	negative selection	851760
227112375	227112398	1	-	26627737	GBM cells	viability after 13 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.6781943157494057	[482]	[479,369]	8	hSpCas9	negative selection	934070
227112742	227112765	1	-	26627737	GBM cells	viability after 13 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.5244793057394754	[396]	[332,290]	6	hSpCas9	negative selection	934071
227139704	227139727	1	-	26627737	GBM cells	viability after 13 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.11890598783906159	[184]	[108,108]	1	hSpCas9	negative selection	934072
227145700	227145723	1	+	26627737	GBM cells	viability after 13 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-0.9820273685929723	[136]	[62,16]	-8	hSpCas9	negative selection	934073
227147489	227147512	1	-	26627737	GBM cells	viability after 13 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.4941131800646276	[243]	[218,159]	6	hSpCas9	negative selection	934074
227317115	227317138	1	-	26627737	GBM cells	viability after 13 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.48494562333548696	[124]	[68,115]	6	hSpCas9	negative selection	934075
227112375	227112398	1	-	26627737	GBM cells	viability after 21 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	1.1438760291939625	[482]	[606,554]	9	hSpCas9	negative selection	1016385
227112742	227112765	1	-	26627737	GBM cells	viability after 21 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.6093280385140183	[396]	[339,318]	6	hSpCas9	negative selection	1016386
227139704	227139727	1	-	26627737	GBM cells	viability after 21 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	-0.1018554897539985	[184]	[89,96]	-1	hSpCas9	negative selection	1016387
227145700	227145723	1	+	26627737	GBM cells	viability after 21 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-3.2177987833448682	[136]	[7,7]	-9	hSpCas9	negative selection	1016388
227147489	227147512	1	-	26627737	GBM cells	viability after 21 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.14534659593672813	[243]	[143,148]	1	hSpCas9	negative selection	1016389
227317115	227317138	1	-	26627737	GBM cells	viability after 21 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.272001019571655	[124]	[81,81]	3	hSpCas9	negative selection	1016390
227112375	227112398	1	-	26627737	RPE1	viability after 9 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.23942268592181937	[1841]	[847,464]	1	hSpCas9	negative selection	1098700
227112742	227112765	1	-	26627737	RPE1	viability after 9 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.8196131295279034	[493]	[189,379]	5	hSpCas9	negative selection	1098701
227139704	227139727	1	-	26627737	RPE1	viability after 9 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	-0.2047341098593149	[605]	[37,327]	-1	hSpCas9	negative selection	1098702
227145700	227145723	1	+	26627737	RPE1	viability after 9 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	0.4241623730367723	[474]	[154,256]	3	hSpCas9	negative selection	1098703
227147489	227147512	1	-	26627737	RPE1	viability after 9 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	2.0810097663490907	[318]	[384,470]	9	hSpCas9	negative selection	1098704
227317115	227317138	1	-	26627737	RPE1	viability after 9 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	2.678535341797888	[45]	[65,125]	9	hSpCas9	negative selection	1098705
227112375	227112398	1	-	26627737	RPE1	viability after 12 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.521251690624227	[1841]	[786,628]	3	hSpCas9	negative selection	1181015
227112742	227112765	1	-	26627737	RPE1	viability after 12 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.6774134738944313	[493]	[186,238]	4	hSpCas9	negative selection	1181016
227139704	227139727	1	-	26627737	RPE1	viability after 12 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	-0.5448693548579879	[605]	[63,161]	-4	hSpCas9	negative selection	1181017
227145700	227145723	1	+	26627737	RPE1	viability after 12 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	0.6093309236062076	[474]	[217,169]	4	hSpCas9	negative selection	1181018
227147489	227147512	1	-	26627737	RPE1	viability after 12 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	2.099682209863505	[318]	[429,300]	9	hSpCas9	negative selection	1181019
227317115	227317138	1	-	26627737	RPE1	viability after 12 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	2.8459653036891233	[45]	[32,147]	9	hSpCas9	negative selection	1181020
227112375	227112398	1	-	26627737	RPE1	viability after 15 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.4234245232749534	[1841]	[906,497]	2	hSpCas9	negative selection	1263330
227112742	227112765	1	-	26627737	RPE1	viability after 15 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.38418607851682385	[493]	[160,202]	2	hSpCas9	negative selection	1263331
227139704	227139727	1	-	26627737	RPE1	viability after 15 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	-0.28878871940870127	[605]	[121,157]	-2	hSpCas9	negative selection	1263332
227145700	227145723	1	+	26627737	RPE1	viability after 15 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	1.2313889450815279	[474]	[231,395]	7	hSpCas9	negative selection	1263333
227147489	227147512	1	-	26627737	RPE1	viability after 15 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	2.2038890859851987	[318]	[401,428]	9	hSpCas9	negative selection	1263334
227317115	227317138	1	-	26627737	RPE1	viability after 15 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	2.5015404577067155	[45]	[34,110]	9	hSpCas9	negative selection	1263335
227112375	227112398	1	-	26627737	RPE1	viability after 18 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.7993332220856064	[1841]	[1173,534]	5	hSpCas9	negative selection	1345645
227112742	227112765	1	-	26627737	RPE1	viability after 18 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.6051541822201986	[493]	[152,255]	4	hSpCas9	negative selection	1345646
227139704	227139727	1	-	26627737	RPE1	viability after 18 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	-0.16611846663543878	[605]	[21,277]	-1	hSpCas9	negative selection	1345647
227145700	227145723	1	+	26627737	RPE1	viability after 18 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	0.656806685185655	[474]	[102,307]	4	hSpCas9	negative selection	1345648
227147489	227147512	1	-	26627737	RPE1	viability after 18 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	1.949435330903297	[318]	[375,285]	8	hSpCas9	negative selection	1345649
227317115	227317138	1	-	26627737	RPE1	viability after 18 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	2.0158307218173013	[45]	[26,74]	8	hSpCas9	negative selection	1345650
227112375	227112398	1	-	26627737	HeLa	viability after 8 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.40116885441049255	[585]	[223,418,341]	3	hSpCas9	negative selection	1427960
227112742	227112765	1	-	26627737	HeLa	viability after 8 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-0.2639286069173944	[683]	[246,182,308]	-3	hSpCas9	negative selection	1427961
227139704	227139727	1	-	26627737	HeLa	viability after 8 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.6222771845193626	[206]	[165,102,151]	5	hSpCas9	negative selection	1427962
227145700	227145723	1	+	26627737	HeLa	viability after 8 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	0.0980220436501158	[73]	[0,74,20]	1	hSpCas9	negative selection	1427963
227147489	227147512	1	-	26627737	HeLa	viability after 8 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.9564153761997627	[285]	[262,280,188]	7	hSpCas9	negative selection	1427964
227317115	227317138	1	-	26627737	HeLa	viability after 8 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	-0.4106446673459764	[243]	[69,80,85]	-4	hSpCas9	negative selection	1427965
227112375	227112398	1	-	26627737	HeLa	viability after 12 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.38604000615152667	[585]	[408,241,308]	3	hSpCas9	negative selection	1510275
227112742	227112765	1	-	26627737	HeLa	viability after 12 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-0.40305683868750813	[683]	[237,213,189]	-4	hSpCas9	negative selection	1510276
227139704	227139727	1	-	26627737	HeLa	viability after 12 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	1.6763564057990732	[206]	[467,149,220]	9	hSpCas9	negative selection	1510277
227145700	227145723	1	+	26627737	HeLa	viability after 12 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	0.3269785539981913	[73]	[17,42,52]	3	hSpCas9	negative selection	1510278
227147489	227147512	1	-	26627737	HeLa	viability after 12 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.6872024118944989	[285]	[239,174,158]	5	hSpCas9	negative selection	1510279
227317115	227317138	1	-	26627737	HeLa	viability after 12 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	-0.4811405074156204	[243]	[33,77,102]	-4	hSpCas9	negative selection	1510280
227112375	227112398	1	-	26627737	HeLa	viability after 15 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.4380818563307822	[585]	[396,340,222]	3	hSpCas9	negative selection	1592590
227112742	227112765	1	-	26627737	HeLa	viability after 15 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-0.8273597106558207	[683]	[79,207,185]	-6	hSpCas9	negative selection	1592591
227139704	227139727	1	-	26627737	HeLa	viability after 15 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	1.0380192289644705	[206]	[165,218,130]	7	hSpCas9	negative selection	1592592
227145700	227145723	1	+	26627737	HeLa	viability after 15 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	0.3002976098177115	[73]	[58,14,36]	2	hSpCas9	negative selection	1592593
227147489	227147512	1	-	26627737	HeLa	viability after 15 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.7305696298804252	[285]	[171,224,181]	6	hSpCas9	negative selection	1592594
227317115	227317138	1	-	26627737	HeLa	viability after 15 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.6711033470508284	[243]	[201,112,158]	5	hSpCas9	negative selection	1592595
227112375	227112398	1	-	26627737	HeLa	viability after 18 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.4999362596979158	[585]	[282,295,222]	4	hSpCas9	negative selection	1674905
227112742	227112765	1	-	26627737	HeLa	viability after 18 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-0.8219858228439026	[683]	[54,171,185]	-6	hSpCas9	negative selection	1674906
227139704	227139727	1	-	26627737	HeLa	viability after 18 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	1.1235133114175397	[206]	[124,189,130]	7	hSpCas9	negative selection	1674907
227145700	227145723	1	+	26627737	HeLa	viability after 18 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	0.29782826658135164	[73]	[38,12,36]	2	hSpCas9	negative selection	1674908
227147489	227147512	1	-	26627737	HeLa	viability after 18 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.7288370220762327	[285]	[115,184,181]	6	hSpCas9	negative selection	1674909
227317115	227317138	1	-	26627737	HeLa	viability after 18 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.653225495351154	[243]	[132,91,158]	5	hSpCas9	negative selection	1674910
227112375	227112398	1	-	26627737	HCT116	viability after 6 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.2214197826201922	[672]	[152,106]	1	hSpCas9	negative selection	1757220
227112742	227112765	1	-	26627737	HCT116	viability after 6 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-0.30188935217181656	[877]	[42,149]	-2	hSpCas9	negative selection	1757221
227139704	227139727	1	-	26627737	HCT116	viability after 6 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.47272059115848375	[439]	[153,63]	2	hSpCas9	negative selection	1757222
227145700	227145723	1	+	26627737	HCT116	viability after 6 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-3.4147557875905834	[742]	[28,0]	-9	hSpCas9	negative selection	1757223
227147489	227147512	1	-	26627737	HCT116	viability after 6 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	-1.9476484710403228	[458]	[48,1]	-8	hSpCas9	negative selection	1757224
227317115	227317138	1	-	26627737	HCT116	viability after 6 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	1.392835496593415	[449]	[110,226]	7	hSpCas9	negative selection	1757225
227112375	227112398	1	-	26627737	HCT116	viability after 8 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.0593469974526033	[609]	[324,269,453]	0	hSpCas9	negative selection	1839535
227112742	227112765	1	-	26627737	HCT116	viability after 8 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.32194298313479175	[349]	[266,240,215]	3	hSpCas9	negative selection	1839536
227139704	227139727	1	-	26627737	HCT116	viability after 8 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	1.19659743761716	[147]	[173,156,228]	8	hSpCas9	negative selection	1839537
227145700	227145723	1	+	26627737	HCT116	viability after 8 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-0.772780396268275	[198]	[69,87,34]	-7	hSpCas9	negative selection	1839538
227147489	227147512	1	-	26627737	HCT116	viability after 8 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	1.1299577085704364	[116]	[140,117,163]	8	hSpCas9	negative selection	1839539
227317115	227317138	1	-	26627737	HCT116	viability after 8 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	-1.1309058988800498	[231]	[55,53,64]	-8	hSpCas9	negative selection	1839540
227112375	227112398	1	-	26627737	HCT116	viability after 9 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	1.4032681945319523	[672]	[829,194]	8	hSpCas9	negative selection	1921850
227112742	227112765	1	-	26627737	HCT116	viability after 9 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-1.1494648049538543	[877]	[184,42]	-7	hSpCas9	negative selection	1921851
227139704	227139727	1	-	26627737	HCT116	viability after 9 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.1053387870238846	[439]	[198,68]	0	hSpCas9	negative selection	1921852
227145700	227145723	1	+	26627737	HCT116	viability after 9 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-1.113903281494262	[742]	[132,58]	-7	hSpCas9	negative selection	1921853
227147489	227147512	1	-	26627737	HCT116	viability after 9 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.3734773812904377	[458]	[241,92]	3	hSpCas9	negative selection	1921854
227317115	227317138	1	-	26627737	HCT116	viability after 9 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.5747339267617869	[449]	[164,189]	4	hSpCas9	negative selection	1921855
227112375	227112398	1	-	26627737	HCT116	viability after 12 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.057938392214432755	[609]	[339,268,389]	0	hSpCas9	negative selection	2004165
227112742	227112765	1	-	26627737	HCT116	viability after 12 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.11739353508934006	[349]	[146,273,183]	1	hSpCas9	negative selection	2004166
227139704	227139727	1	-	26627737	HCT116	viability after 12 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.1890300696624686	[147]	[95,73,94]	2	hSpCas9	negative selection	2004167
227145700	227145723	1	+	26627737	HCT116	viability after 12 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-1.098172098250426	[198]	[20,48,78]	-8	hSpCas9	negative selection	2004168
227147489	227147512	1	-	26627737	HCT116	viability after 12 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.7998291926492247	[116]	[96,147,77]	7	hSpCas9	negative selection	2004169
227317115	227317138	1	-	26627737	HCT116	viability after 12 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	-0.9625108309186285	[231]	[51,77,58]	-8	hSpCas9	negative selection	2004170
227112375	227112398	1	-	26627737	HCT116	viability after 15 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.3552513212678239	[609]	[744,226,408]	3	hSpCas9	negative selection	2086480
227112742	227112765	1	-	26627737	HCT116	viability after 15 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.37104738751763067	[349]	[282,183,314]	3	hSpCas9	negative selection	2086481
227139704	227139727	1	-	26627737	HCT116	viability after 15 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.7256349418721125	[147]	[169,94,159]	6	hSpCas9	negative selection	2086482
227145700	227145723	1	+	26627737	HCT116	viability after 15 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-2.689120827317513	[198]	[8,16,25]	-9	hSpCas9	negative selection	2086483
227147489	227147512	1	-	26627737	HCT116	viability after 15 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	1.1557333057060757	[116]	[227,110,119]	8	hSpCas9	negative selection	2086484
227317115	227317138	1	-	26627737	HCT116	viability after 15 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	-0.5913232642835732	[231]	[75,33,152]	-6	hSpCas9	negative selection	2086485
227112375	227112398	1	-	26627737	HCT116	viability after 18 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	-0.05905453658468862	[609]	[217,405,213]	0	hSpCas9	negative selection	2168795
227112742	227112765	1	-	26627737	HCT116	viability after 18 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.40767710125985235	[349]	[119,244,310]	3	hSpCas9	negative selection	2168796
227139704	227139727	1	-	26627737	HCT116	viability after 18 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	-0.5563193199591281	[147]	[17,60,66]	-5	hSpCas9	negative selection	2168797
227145700	227145723	1	+	26627737	HCT116	viability after 18 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-1.2998869469221832	[198]	[11,34,71]	-8	hSpCas9	negative selection	2168798
227147489	227147512	1	-	26627737	HCT116	viability after 18 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.891459776946459	[116]	[101,129,79]	7	hSpCas9	negative selection	2168799
227317115	227317138	1	-	26627737	HCT116	viability after 18 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	-0.6270487409945683	[231]	[88,21,111]	-5	hSpCas9	negative selection	2168800
227317005	227317028	1	-	24336569	HL60	viability	CATTCTCGAATACCTAGAATGGG	CDC42BPA	ENSG00000143776	1.2387195018561998	[330]	[1652]	8	hSpCas9	negative selection	2256395
227317025	227317048	1	+	24336569	HL60	viability	ATGTTCTTCTCTCTTCTCAATGG	CDC42BPA	ENSG00000143776	-0.2078754801712055	[297]	[545]	-2	hSpCas9	negative selection	2256396
227317050	227317073	1	+	24336569	HL60	viability	AATTATTGCATTCATCATAAAGG	CDC42BPA	ENSG00000143776	1.1861301446915002	[486]	[2344]	8	hSpCas9	negative selection	2256397
227317086	227317109	1	-	24336569	HL60	viability	CTTCAGTGTGGAGACATTACTGG	CDC42BPA	ENSG00000143776	1.1703191702301887	[471]	[2247]	8	hSpCas9	negative selection	2256398
227317099	227317122	1	+	24336569	HL60	viability	CACACTGAAGCACTGCCCATTGG	CDC42BPA	ENSG00000143776	0.08225436454063084	[1992]	[4464]	0	hSpCas9	negative selection	2256399
227317108	227317131	1	+	24336569	HL60	viability	GCACTGCCCATTGGTCTGAGCGG	CDC42BPA	ENSG00000143776	0.49208461397017067	[845]	[2517]	4	hSpCas9	negative selection	2256400
227317114	227317137	1	-	24336569	HL60	viability	ACGGGCCCGCTCAGACCAATGGG	CDC42BPA	ENSG00000143776	0.22536115693961833	[748]	[1852]	2	hSpCas9	negative selection	2256401
227317152	227317175	1	-	24336569	HL60	viability	AGAAGTGCGTTTGAGGCAGTTGG	CDC42BPA	ENSG00000143776	-0.7345740940316414	[1695]	[2156]	-6	hSpCas9	negative selection	2256402
227317159	227317182	1	-	24336569	HL60	viability	TGTCTGGAGAAGTGCGTTTGAGG	CDC42BPA	ENSG00000143776	0.8950450947849448	[742]	[2923]	7	hSpCas9	negative selection	2256403
227317175	227317198	1	-	24336569	HL60	viability	GAAATCGAAGCAAACATGTCTGG	CDC42BPA	ENSG00000143776	1.0668809827684653	[463]	[2056]	7	hSpCas9	negative selection	2256404
227317005	227317028	1	-	24336569	KBM7	viability	CATTCTCGAATACCTAGAATGGG	CDC42BPA	ENSG00000143776	0.5999574602886976	[402]	[1665]	5	hSpCas9	negative selection	2323572
227317025	227317048	1	+	24336569	KBM7	viability	ATGTTCTTCTCTCTTCTCAATGG	CDC42BPA	ENSG00000143776	1.0284228843746968	[180]	[1006]	8	hSpCas9	negative selection	2323573
227317050	227317073	1	+	24336569	KBM7	viability	AATTATTGCATTCATCATAAAGG	CDC42BPA	ENSG00000143776	0.8164715496164041	[472]	[2271]	7	hSpCas9	negative selection	2323574
227317086	227317109	1	-	24336569	KBM7	viability	CTTCAGTGTGGAGACATTACTGG	CDC42BPA	ENSG00000143776	0.8922074204241356	[561]	[2844]	7	hSpCas9	negative selection	2323575
227317099	227317122	1	+	24336569	KBM7	viability	CACACTGAAGCACTGCCCATTGG	CDC42BPA	ENSG00000143776	-0.5211716028475153	[1859]	[3534]	-4	hSpCas9	negative selection	2323576
227317108	227317131	1	+	24336569	KBM7	viability	GCACTGCCCATTGGTCTGAGCGG	CDC42BPA	ENSG00000143776	0.3101178392014101	[759]	[2569]	3	hSpCas9	negative selection	2323577
227317114	227317137	1	-	24336569	KBM7	viability	ACGGGCCCGCTCAGACCAATGGG	CDC42BPA	ENSG00000143776	0.29629132274984715	[666]	[2233]	2	hSpCas9	negative selection	2323578
227317152	227317175	1	-	24336569	KBM7	viability	AGAAGTGCGTTTGAGGCAGTTGG	CDC42BPA	ENSG00000143776	0.5185712913088723	[1228]	[4801]	5	hSpCas9	negative selection	2323579
227317159	227317182	1	-	24336569	KBM7	viability	TGTCTGGAGAAGTGCGTTTGAGG	CDC42BPA	ENSG00000143776	0.8093064024342971	[675]	[3230]	7	hSpCas9	negative selection	2323580
227317175	227317198	1	-	24336569	KBM7	viability	GAAATCGAAGCAAACATGTCTGG	CDC42BPA	ENSG00000143776	0.6150461386053185	[416]	[1741]	5	hSpCas9	negative selection	2323581
227317137	227317159	1	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CAGTTGGAGCAGTTTATTTTGG	CDC42BPA	ENSG00000143776	2.8294056821482085	[3938,2502,3524]	[0,11,14]	6	hSpCas9	positive selection	2380693
227317137	227317159	1	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CAGTTGGAGCAGTTTATTTTGG	CDC42BPA	ENSG00000143776	2.8294056821482085	[3938,2502,3524]	[0,11,14]	6	hSpCas9	positive selection	2380694
227317115	227317137	1	-	24717434	HeLa	essential genes for diphteria toxin toxicity	ACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	-0.528203553399241	[4417,3349,3185]	[0,0,0]	-5	hSpCas9	positive selection	2380695
227317115	227317137	1	-	24717434	HeLa	essential genes for diphteria toxin toxicity	ACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	-0.528203553399241	[4417,3349,3185]	[0,0,0]	-5	hSpCas9	positive selection	2380696
227317137	227317159	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CAGTTGGAGCAGTTTATTTTGG	CDC42BPA	ENSG00000143776	4.892939513920019	[3938,2502,3524]	[77,0,37]	7	hSpCas9	positive selection	2381858
227317137	227317159	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CAGTTGGAGCAGTTTATTTTGG	CDC42BPA	ENSG00000143776	4.892939513920019	[3938,2502,3524]	[77,0,37]	7	hSpCas9	positive selection	2381859
227317115	227317137	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	5.153286547507767	[4417,3349,3185]	[151,0,0]	8	hSpCas9	positive selection	2381860
227317115	227317137	1	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	5.153286547507767	[4417,3349,3185]	[151,0,0]	8	hSpCas9	positive selection	2381861
227195275	227195298	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACTTGAACCCAGGAGGCAGGGG	CDC42BPA	ENSG00000143776	-1.4184778160092897	[54,284]	[10,16]	-7	dCas9-VP64	positive selection	2414549
227309106	227309129	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTAATCCCAGCACTTTGGGGAG	CDC42BPA	ENSG00000143776	-1.8840232515636643	[4,58]	[0,1]	-9	dCas9-VP64	positive selection	2423278
227318233	227318256	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCCCCCTTCTTCACACCCCTGG	CDC42BPA	ENSG00000143776	-1.1688954003490886	[617,446]	[53,48]	-6	dCas9-VP64	positive selection	2433216
227318280	227318303	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGGGAGGCGGCCCGGCGCAGG	CDC42BPA	ENSG00000143776	1.0925771296326023	[12,9]	[3,6]	4	dCas9-VP64	positive selection	2433217
227318251	227318274	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGAAAGATGCCCTTAGCCCAGG	CDC42BPA	ENSG00000143776	0.5149726072354648	[59,149]	[30,34]	2	dCas9-VP64	positive selection	2433218
227082452	227082475	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCCCAGCACTTTGG	CDC42BPA	ENSG00000143776	-0.7697329427055237	[305,492]	[31,71]	-4	dCas9-VP64	positive selection	2453226
227095840	227095863	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTCAGCCTCCCAAAGTGCTCAG	CDC42BPA	ENSG00000143776	-0.5682190535479439	[619,834]	[60,158]	-3	dCas9-VP64	positive selection	2453279
227277787	227277810	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCCCAGGCTGGAGTGCAGTGG	CDC42BPA	ENSG00000143776	0.5070772209909733	[97,61]	[39,7]	2	dCas9-VP64	positive selection	2477717
227195275	227195298	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACTTGAACCCAGGAGGCAGGGG	CDC42BPA	ENSG00000143776	0.5761613238144463	[143,285]	[83,121]	4	dCas9-VP64	positive selection	2509804
227309106	227309129	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTAATCCCAGCACTTTGGGGAG	CDC42BPA	ENSG00000143776	-0.3040415459965904	[20,19]	[5,3]	-3	dCas9-VP64	positive selection	2518533
227318233	227318256	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCCCCCTTCTTCACACCCCTGG	CDC42BPA	ENSG00000143776	-0.13199398121280326	[507,406]	[110,159]	-1	dCas9-VP64	positive selection	2528471
227318280	227318303	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGGGAGGCGGCCCGGCGCAGG	CDC42BPA	ENSG00000143776	0.9439328664457289	[21,26]	[15,13]	6	dCas9-VP64	positive selection	2528472
227318251	227318274	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGAAAGATGCCCTTAGCCCAGG	CDC42BPA	ENSG00000143776	0.3092349668212176	[31,104]	[23,28]	2	dCas9-VP64	positive selection	2528473
227082452	227082475	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCCCAGCACTTTGG	CDC42BPA	ENSG00000143776	-0.7960951384238878	[400,199]	[64,47]	-7	dCas9-VP64	positive selection	2548481
227095840	227095863	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTCAGCCTCCCAAAGTGCTCAG	CDC42BPA	ENSG00000143776	-0.30228362212427595	[344,254]	[89,69]	-3	dCas9-VP64	positive selection	2548534
227277787	227277810	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCCCAGGCTGGAGTGCAGTGG	CDC42BPA	ENSG00000143776	-0.06949214303462026	[365,454]	[80,170]	0	dCas9-VP64	positive selection	2572972
227074337	227074360	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.34575847483815775	[3,3]	[4,4]	7	hSpCas9	positive selection	2977935
227213135	227213158	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.15899165434152235	[4,5]	[4,5]	3	hSpCas9	positive selection	2977936
227142955	227142978	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTATATGTAAAACCAACAAATGG	CDC42BPA	ENSG00000143776	-0.5442524283013617	[1,3]	[2,0]	-7	hSpCas9	positive selection	2977937
227147544	227147567	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTTCAGGTTCAGTCCTCAGTGG	CDC42BPA	ENSG00000143776	0.2723170705344786	[5,5]	[5,5]	6	hSpCas9	positive selection	2977938
227074337	227074360	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-0.2235294423228036	[3,3]	[3,1]	-3	hSpCas9	positive selection	3045793
227213135	227213158	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.04981109110471316	[4,4]	[3,3]	0	hSpCas9	positive selection	3045794
227142955	227142978	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTATATGTAAAACCAACAAATGG	CDC42BPA	ENSG00000143776	0.22184382976522554	[1,1]	[1,0]	4	hSpCas9	positive selection	3045795
227147544	227147567	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTTCAGGTTCAGTCCTCAGTGG	CDC42BPA	ENSG00000143776	-0.1191035775915274	[5,5]	[4,2]	-2	hSpCas9	positive selection	3045796
227254090	227254113		-	24336571	A375	resistance to PLX after 7 days	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.16881096474125634	[4,4]	[3,3]	-5	hSpCas9	positive selection	3104353
227199629	227199652		-	24336571	A375	resistance to PLX after 7 days	CAGCATGTTTTCGTGAAGAAAGG	CDC42BPA	ENSG00000143776	0.10219438653845936	[18,16]	[20,17]	3	hSpCas9	positive selection	3104355
227254067	227254090		-	24336571	A375	resistance to PLX after 7 days	TGATTGGTCGAGGAGCTTTTGGG	CDC42BPA	ENSG00000143776	0.32207437525081384	[23,22]	[27,29]	8	hSpCas9	positive selection	3104356
227254128	227254151		+	24336571	A375	resistance to PLX after 7 days	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	-0.22375516629734205	[6,6]	[4,6]	-6	hSpCas9	positive selection	3104357
227254090	227254113		-	24336571	A375	resistance to PLX after 14 days	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.31883721022233713	[3,3]	[1,2]	3	hSpCas9	positive selection	3162146
227199629	227199652		-	24336571	A375	resistance to PLX after 14 days	CAGCATGTTTTCGTGAAGAAAGG	CDC42BPA	ENSG00000143776	2.028742526366083	[27,14]	[36,45]	9	hSpCas9	positive selection	3162148
227254067	227254090		-	24336571	A375	resistance to PLX after 14 days	TGATTGGTCGAGGAGCTTTTGGG	CDC42BPA	ENSG00000143776	0.7265934279766115	[18,27]	[18,16]	6	hSpCas9	positive selection	3162149
227254128	227254151		+	24336571	A375	resistance to PLX after 14 days	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	-0.3938072674922941	[7,8]	[1,3]	-5	hSpCas9	positive selection	3162150
227254090	227254113		-	24336571	A375	viability after 7 days	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.7217203656368478	[8]	[4,4]	-8	hSpCas9	negative selection	3219939
227199629	227199652		-	24336571	A375	viability after 7 days	CAGCATGTTTTCGTGAAGAAAGG	CDC42BPA	ENSG00000143776	-0.034602201631404705	[19]	[18,16]	0	hSpCas9	negative selection	3219941
227254067	227254090		-	24336571	A375	viability after 7 days	TGATTGGTCGAGGAGCTTTTGGG	CDC42BPA	ENSG00000143776	0.10200141765990145	[22]	[23,22]	1	hSpCas9	negative selection	3219942
227254128	227254151		+	24336571	A375	viability after 7 days	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	-0.47958535588459855	[10]	[6,6]	-6	hSpCas9	negative selection	3219943
227254090	227254113		-	24336571	A375	viability after 14 days	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.9312971583660639	[8]	[3,3]	-8	hSpCas9	negative selection	3277732
227199629	227199652		-	24336571	A375	viability after 14 days	CAGCATGTTTTCGTGAAGAAAGG	CDC42BPA	ENSG00000143776	0.20691001159897182	[19]	[27,14]	2	hSpCas9	negative selection	3277734
227254067	227254090		-	24336571	A375	viability after 14 days	TGATTGGTCGAGGAGCTTTTGGG	CDC42BPA	ENSG00000143776	0.1256969003133772	[22]	[18,27]	1	hSpCas9	negative selection	3277735
227254128	227254151		+	24336571	A375	viability after 14 days	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	-0.16589464744691734	[10]	[7,8]	-2	hSpCas9	negative selection	3277736
227199571	227199594	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	-1.1286066611616465	[336,331]	[0,0]	-7	hSpCas9	positive selection	3342218
227193910	227193933	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.14300546305847747	[146,129]	[0,0]	0	hSpCas9	positive selection	3342219
227193922	227193945	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	-0.4091704922468475	[227,177]	[0,0]	-3	hSpCas9	positive selection	3342220
227199553	227199576	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	2.2598330670564097	[574,574]	[17,17]	8	hSpCas9	positive selection	3361448
227254128	227254151	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.1280431945008686	[139,139]	[0,0]	0	hSpCas9	positive selection	3361449
227254090	227254113	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.21293209208738176	[131,131]	[0,0]	1	hSpCas9	positive selection	3361450
227074337	227074360	1	-	26780180	HT29	viability (Avana library 4 designs)	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.103754502923475	[]	[]	0	hSpCas9	negative selection	3414244
227213135	227213158	1	-	26780180	HT29	viability (Avana library 4 designs)	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	-0.587545220809619	[]	[]	-8	hSpCas9	negative selection	3414245
227142954	227142977	1	+	26780180	HT29	viability (Avana library 4 designs)	GTATATGTAAAACCAACAAATGG	CDC42BPA	ENSG00000143776	0.765374463539265	[]	[]	3	hSpCas9	negative selection	3414246
227147544	227147567	1	-	26780180	HT29	viability (Avana library 4 designs)	TCTTCAGGTTCAGTCCTCAGTGG	CDC42BPA	ENSG00000143776	-0.0885301057024574	[]	[]	-1	hSpCas9	negative selection	3414247
227213135	227213158	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	2.72718943425335	[]	[]	4	hSpCas9	negative selection	3490664
227142954	227142977	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTATATGTAAAACCAACAAATGG	CDC42BPA	ENSG00000143776	-15.4885492194817	[]	[]	-9	hSpCas9	negative selection	3490665
227074337	227074360	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-8.60734096997481	[]	[]	-7	hSpCas9	negative selection	3490666
227147544	227147567	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTCAGGTTCAGTCCTCAGTGG	CDC42BPA	ENSG00000143776	2.41283531718157	[]	[]	3	hSpCas9	negative selection	3490667
227139727	227139750	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTCAGTGTACTTTCTGATCGG	CDC42BPA	ENSG00000143776	-2.92046816437238	[]	[]	-3	hSpCas9	negative selection	3490668
227145643	227145666	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.834431993607395	[]	[]	1	hSpCas9	negative selection	3490669
227213135	227213158	1	-	26780180	A375	viability (Avana lentiGuide)	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.719504553578874	[]	[]	0	hSpCas9	negative selection	3599323
227142954	227142977	1	+	26780180	A375	viability (Avana lentiGuide)	GTATATGTAAAACCAACAAATGG	CDC42BPA	ENSG00000143776	2.74957251907633	[]	[]	3	hSpCas9	negative selection	3599324
227074337	227074360	1	-	26780180	A375	viability (Avana lentiGuide)	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-0.627166402234039	[]	[]	-1	hSpCas9	negative selection	3599325
227147544	227147567	1	-	26780180	A375	viability (Avana lentiGuide)	TCTTCAGGTTCAGTCCTCAGTGG	CDC42BPA	ENSG00000143776	0.516718801741338	[]	[]	0	hSpCas9	negative selection	3599326
227139727	227139750	1	-	26780180	A375	viability (Avana lentiGuide)	TCTTCAGTGTACTTTCTGATCGG	CDC42BPA	ENSG00000143776	-2.34084371318991	[]	[]	-4	hSpCas9	negative selection	3599327
227145643	227145666	1	-	26780180	A375	viability (Avana lentiGuide)	TGTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	6.32427558890916	[]	[]	5	hSpCas9	negative selection	3599328
227213135	227213158	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.10111355477321837	[6]	[5,6]	2	hSpCas9	positive selection	3707982
227142954	227142977	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATATGTAAAACCAACAAATGG	CDC42BPA	ENSG00000143776	-1.5120974731006527	[8]	[3,1]	-9	hSpCas9	positive selection	3707983
227074337	227074360	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-0.4777950167179422	[5]	[4,2]	-6	hSpCas9	positive selection	3707984
227147544	227147567	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTCAGGTTCAGTCCTCAGTGG	CDC42BPA	ENSG00000143776	0.14927174503769836	[6]	[7,6]	4	hSpCas9	positive selection	3707985
227139727	227139750	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTCAGTGTACTTTCTGATCGG	CDC42BPA	ENSG00000143776	-0.19196378533608383	[8]	[7,6]	-3	hSpCas9	positive selection	3707986
227145643	227145666	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.02407092434900957	[5]	[4,5]	0	hSpCas9	positive selection	3707987
227213135	227213158	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.3303100377802171	[6]	[6,6]	8	hSpCas9	positive selection	3816589
227142954	227142977	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATATGTAAAACCAACAAATGG	CDC42BPA	ENSG00000143776	-0.3214794063485391	[4]	[1,3]	-4	hSpCas9	positive selection	3816590
227074337	227074360	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.005943725557690294	[5]	[5,3]	0	hSpCas9	positive selection	3816591
227147544	227147567	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTCAGGTTCAGTCCTCAGTGG	CDC42BPA	ENSG00000143776	0.3367099929661646	[7]	[7,8]	8	hSpCas9	positive selection	3816592
227139727	227139750	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTCAGTGTACTTTCTGATCGG	CDC42BPA	ENSG00000143776	0.2099282766436174	[7]	[7,7]	5	hSpCas9	positive selection	3816593
227145643	227145666	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	-0.44768055480462826	[5]	[2,3]	-5	hSpCas9	positive selection	3816594
227199571	227199594	1	-	26780180	A375	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	1.02368624231293	[]	[]	5	hSpCas9	negative selection	3924763
227254090	227254113	1	-	26780180	A375	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.215220892326953	[]	[]	0	hSpCas9	negative selection	3924764
227193910	227193933	1	+	26780180	A375	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	1.15600946466673	[]	[]	6	hSpCas9	negative selection	3924765
227193922	227193945	1	-	26780180	A375	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.795741479636449	[]	[]	3	hSpCas9	negative selection	3924766
227254128	227254151	1	+	26780180	A375	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.767638277185578	[]	[]	3	hSpCas9	negative selection	3924767
227199553	227199576	1	+	26780180	A375	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	1.12026444064635	[]	[]	5	hSpCas9	negative selection	3924768
227199571	227199594	1	-	26780180	HT29	viability (GeCKOv2 library)	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.498452514787458	[]	[]	1	hSpCas9	negative selection	4032729
227254090	227254113	1	-	26780180	HT29	viability (GeCKOv2 library)	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.873095870352054	[]	[]	3	hSpCas9	negative selection	4032730
227193910	227193933	1	+	26780180	HT29	viability (GeCKOv2 library)	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	1.67774871953132	[]	[]	8	hSpCas9	negative selection	4032731
227193922	227193945	1	-	26780180	HT29	viability (GeCKOv2 library)	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.30073396791573	[]	[]	0	hSpCas9	negative selection	4032732
227254128	227254151	1	+	26780180	HT29	viability (GeCKOv2 library)	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	1.36707877841478	[]	[]	7	hSpCas9	negative selection	4032733
227199553	227199576	1	+	26780180	HT29	viability (GeCKOv2 library)	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	1.13253011828192	[]	[]	5	hSpCas9	negative selection	4032734
227254090	227254113	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.16842098465135846	[1]	[0,0]	-4	hSpCas9	positive selection	4126359
227199629	227199652	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAGCATGTTTTCGTGAAGAAAGG	CDC42BPA	ENSG00000143776	0.49605523581538463	[4]	[2,5]	9	hSpCas9	positive selection	4126361
227254067	227254090	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGATTGGTCGAGGAGCTTTTGGG	CDC42BPA	ENSG00000143776	0.2116596244710024	[4]	[3,4]	5	hSpCas9	positive selection	4126362
227254128	227254151	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	-0.20864841744755702	[2]	[1,1]	-5	hSpCas9	positive selection	4126363
227254090	227254113	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.4868140973779479	[2]	[1,0,0,0]	-7	hSpCas9	positive selection	4190381
227199629	227199652	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAGCATGTTTTCGTGAAGAAAGG	CDC42BPA	ENSG00000143776	0.1392865625247269	[3]	[2,2,2,0]	1	hSpCas9	positive selection	4190383
227254067	227254090	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGATTGGTCGAGGAGCTTTTGGG	CDC42BPA	ENSG00000143776	1.1656621421255904	[4]	[4,2,1,5]	8	hSpCas9	positive selection	4190384
227254128	227254151	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.4110387837535592	[3]	[1,0,1,2]	3	hSpCas9	positive selection	4190385
227199571	227199594	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.18276001097349448	[4]	[4,2]	3	hSpCas9	positive selection	4262255
227193910	227193933	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.09092174676703627	[2]	[1,2]	1	hSpCas9	positive selection	4262256
227193922	227193945	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.11019717985043381	[3]	[3,2]	2	hSpCas9	positive selection	4262257
227199553	227199576	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.2754096539583136	[4]	[4,4]	5	hSpCas9	positive selection	4326532
227254128	227254151	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.35918650886766823	[2]	[2,2]	7	hSpCas9	positive selection	4326533
227254090	227254113	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.02668146694813217	[2]	[2,1]	0	hSpCas9	positive selection	4326534
227074260	227074282	1	+	27760321	OCIAML3	viability	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	0.45491974908659477	[455,472]	[462,548]	5	hSpCas9	negative selection	4387716
227074348	227074370	1	-	27760321	OCIAML3	viability	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.5056290691340197	[212,192]	[206,248]	6	hSpCas9	negative selection	4387717
227143010	227143032	1	+	27760321	OCIAML3	viability	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.6002497018817758	[385,311]	[368,466]	7	hSpCas9	negative selection	4387718
227145643	227145665	1	-	27760321	OCIAML3	viability	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.20951042759101746	[343,287]	[212,377]	2	hSpCas9	negative selection	4387719
227317004	227317026	1	-	27760321	OCIAML3	viability	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	-0.16705436511547056	[83,87]	[31,96]	-2	hSpCas9	negative selection	4387720
227074260	227074282	1	+	27760321	OCIAML2	viability	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	-0.2244556469656696	[455,472]	[257,408]	-3	hSpCas9	negative selection	4471179
227074348	227074370	1	-	27760321	OCIAML2	viability	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.1268682203618403	[212,192]	[173,185]	1	hSpCas9	negative selection	4471180
227143010	227143032	1	+	27760321	OCIAML2	viability	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	-0.19114313776259734	[385,311]	[210,291]	-2	hSpCas9	negative selection	4471181
227145643	227145665	1	-	27760321	OCIAML2	viability	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	-0.47839041892948075	[343,287]	[155,217]	-5	hSpCas9	negative selection	4471182
227317004	227317026	1	-	27760321	OCIAML2	viability	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	-1.908272271767129	[83,87]	[9,29]	-9	hSpCas9	negative selection	4471183
227074260	227074282	1	+	27760321	MV411	viability	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	0.59059162315362	[455,472]	[454,476]	4	hSpCas9	negative selection	4554642
227074348	227074370	1	-	27760321	MV411	viability	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.6768836731787067	[212,192]	[209,219]	5	hSpCas9	negative selection	4554643
227143010	227143032	1	+	27760321	MV411	viability	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.8236468969015861	[385,311]	[167,761]	6	hSpCas9	negative selection	4554644
227145643	227145665	1	-	27760321	MV411	viability	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.6405842487558397	[343,287]	[71,701]	5	hSpCas9	negative selection	4554645
227317004	227317026	1	-	27760321	MV411	viability	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	0.40185626475566094	[83,87]	[38,129]	3	hSpCas9	negative selection	4554646
227074260	227074282	1	+	27760321	HL60	viability	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	-0.1259585263499313	[455,472]	[361,335]	-1	hSpCas9	negative selection	4638105
227074348	227074370	1	-	27760321	HL60	viability	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.02951947069016736	[212,192]	[106,234]	0	hSpCas9	negative selection	4638106
227143010	227143032	1	+	27760321	HL60	viability	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.3300257535715303	[385,311]	[237,481]	4	hSpCas9	negative selection	4638107
227145643	227145665	1	-	27760321	HL60	viability	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.1637617323580728	[343,287]	[221,357]	2	hSpCas9	negative selection	4638108
227317004	227317026	1	-	27760321	HL60	viability	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	-0.5846454527032741	[83,87]	[49,43]	-6	hSpCas9	negative selection	4638109
227074260	227074282	1	+	27760321	HT1080	viability	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	0.9254470889893247	[472,368]	[297,340]	5	hSpCas9	negative selection	4721568
227074348	227074370	1	-	27760321	HT1080	viability	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	-1.5497579549283975	[192,150]	[31,13]	-5	hSpCas9	negative selection	4721569
227143010	227143032	1	+	27760321	HT1080	viability	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.7473937927925092	[311,243]	[131,244]	4	hSpCas9	negative selection	4721570
227145643	227145665	1	-	27760321	HT1080	viability	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	-0.26498747185200494	[287,224]	[106,60]	-1	hSpCas9	negative selection	4721571
227317004	227317026	1	-	27760321	HT1080	viability	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	0.2467119731388523	[87,68]	[28,45]	1	hSpCas9	negative selection	4721572
227074260	227074282	1	+	27760321	HT29	viability after 7 days	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	-0.49053900392667676	[472,368]	[524,228,419]	-6	hSpCas9	negative selection	4805031
227074348	227074370	1	-	27760321	HT29	viability after 7 days	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.21520139139371497	[192,150]	[284,329,161]	3	hSpCas9	negative selection	4805032
227143010	227143032	1	+	27760321	HT29	viability after 7 days	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.21376942378634295	[311,243]	[452,457,339]	3	hSpCas9	negative selection	4805033
227145643	227145665	1	-	27760321	HT29	viability after 7 days	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.6583215856281306	[287,224]	[322,700,508]	8	hSpCas9	negative selection	4805034
227317004	227317026	1	-	27760321	HT29	viability after 7 days	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	-0.3315722309088027	[87,68]	[91,93,56]	-5	hSpCas9	negative selection	4805035
227074260	227074282	1	+	27760321	HT29	viability after 25 days	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	0.11301715902072945	[472,368]	[628,380,545]	1	hSpCas9	negative selection	4888494
227074348	227074370	1	-	27760321	HT29	viability after 25 days	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.6787961394437216	[192,150]	[255,327,368]	7	hSpCas9	negative selection	4888495
227143010	227143032	1	+	27760321	HT29	viability after 25 days	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.9085258210044451	[311,243]	[552,513,738]	9	hSpCas9	negative selection	4888496
227145643	227145665	1	-	27760321	HT29	viability after 25 days	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.42819404823759255	[287,224]	[180,475,555]	4	hSpCas9	negative selection	4888497
227317004	227317026	1	-	27760321	HT29	viability after 25 days	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	0.6847574383898292	[87,68]	[182,137,104]	7	hSpCas9	negative selection	4888498
227074260	227074282	1	+	27760321	HT29	viability after 22 days	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	0.14320053739397592	[472,368]	[479,485,648]	1	hSpCas9	negative selection	4971957
227074348	227074370	1	-	27760321	HT29	viability after 22 days	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.25732709927868647	[192,150]	[191,214,307]	2	hSpCas9	negative selection	4971958
227143010	227143032	1	+	27760321	HT29	viability after 22 days	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.5575483065432286	[311,243]	[196,611,618]	6	hSpCas9	negative selection	4971959
227145643	227145665	1	-	27760321	HT29	viability after 22 days	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.5601593173339255	[287,224]	[270,626,417]	6	hSpCas9	negative selection	4971960
227317004	227317026	1	-	27760321	HT29	viability after 22 days	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	-1.0812518714017747	[87,68]	[37,30,59]	-7	hSpCas9	negative selection	4971961
227074260	227074282	1	+	27760321	HT29	viability after 19 days	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	-0.06256362138841068	[472,368]	[543,399,447]	0	hSpCas9	negative selection	5055420
227074348	227074370	1	-	27760321	HT29	viability after 19 days	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.7125078989726645	[192,150]	[192,158,590]	7	hSpCas9	negative selection	5055421
227143010	227143032	1	+	27760321	HT29	viability after 19 days	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.9393404591420227	[311,243]	[570,486,760]	8	hSpCas9	negative selection	5055422
227145643	227145665	1	-	27760321	HT29	viability after 19 days	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.019552506346378007	[287,224]	[432,252,222]	0	hSpCas9	negative selection	5055423
227317004	227317026	1	-	27760321	HT29	viability after 19 days	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	0.2660575893017978	[87,68]	[192,63,76]	2	hSpCas9	negative selection	5055424
227074260	227074282	1	+	27760321	HT29	viability after 16 days	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	-0.09868055005025855	[472,368]	[368,394,549]	-1	hSpCas9	negative selection	5138883
227074348	227074370	1	-	27760321	HT29	viability after 16 days	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.4260588816151607	[192,150]	[228,178,366]	5	hSpCas9	negative selection	5138884
227143010	227143032	1	+	27760321	HT29	viability after 16 days	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.7816009336646315	[311,243]	[379,553,654]	8	hSpCas9	negative selection	5138885
227145643	227145665	1	-	27760321	HT29	viability after 16 days	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.3550482719201178	[287,224]	[437,437,229]	4	hSpCas9	negative selection	5138886
227317004	227317026	1	-	27760321	HT29	viability after 16 days	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	-0.24887132071428164	[87,68]	[129,76,19]	-3	hSpCas9	negative selection	5138887
227074260	227074282	1	+	27760321	HT29	viability after 13 days	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	0.03163153389172635	[472,368]	[398,568,527]	0	hSpCas9	negative selection	5222346
227074348	227074370	1	-	27760321	HT29	viability after 13 days	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.25521487346843097	[192,150]	[245,306,165]	3	hSpCas9	negative selection	5222347
227143010	227143032	1	+	27760321	HT29	viability after 13 days	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.37202642950444836	[311,243]	[259,547,442]	5	hSpCas9	negative selection	5222348
227145643	227145665	1	-	27760321	HT29	viability after 13 days	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.1374406054924998	[287,224]	[228,371,377]	1	hSpCas9	negative selection	5222349
227317004	227317026	1	-	27760321	HT29	viability after 13 days	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	-0.2750464834782895	[87,68]	[64,87,72]	-3	hSpCas9	negative selection	5222350
227074260	227074282	1	+	27760321	HT29	viability after 10 days	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	-0.27495367107061425	[472,368]	[276,440,581]	-4	hSpCas9	negative selection	5305809
227074348	227074370	1	-	27760321	HT29	viability after 10 days	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	0.5746996424335261	[192,150]	[300,395,265]	7	hSpCas9	negative selection	5305810
227143010	227143032	1	+	27760321	HT29	viability after 10 days	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.3186787965510007	[311,243]	[314,449,531]	4	hSpCas9	negative selection	5305811
227145643	227145665	1	-	27760321	HT29	viability after 10 days	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	0.12174693755445964	[287,224]	[283,389,371]	1	hSpCas9	negative selection	5305812
227317004	227317026	1	-	27760321	HT29	viability after 10 days	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	-0.4857298322450454	[87,68]	[110,10,85]	-6	hSpCas9	negative selection	5305813
227074260	227074282	1	+	27760321	MOLM13	viability	GTTGCTCGTGTACCCAAGCTGG	CDC42BPA	ENSG00000143776	0.14341074825586075	[455,472]	[413,185]	1	hSpCas9	negative selection	5389272
227074348	227074370	1	-	27760321	MOLM13	viability	TCTAGGGTCAGCGATGAAAAGG	CDC42BPA	ENSG00000143776	-0.9279486978782847	[212,192]	[84,38]	-5	hSpCas9	negative selection	5389273
227143010	227143032	1	+	27760321	MOLM13	viability	TGGGGGCATCGTTTCCTAAAGG	CDC42BPA	ENSG00000143776	0.6021066459989461	[385,311]	[138,431]	4	hSpCas9	negative selection	5389274
227145643	227145665	1	-	27760321	MOLM13	viability	GTAGCAGAGAACATCGACTTGG	CDC42BPA	ENSG00000143776	-0.2624529861281262	[343,287]	[86,199]	-2	hSpCas9	negative selection	5389275
227317004	227317026	1	-	27760321	MOLM13	viability	TTCTCGAATACCTAGAATGGGG	CDC42BPA	ENSG00000143776	0.35958894917313255	[83,87]	[0,114]	2	hSpCas9	negative selection	5389276
227318472	227318495	1	+	27661255	K562	viability	GGACGAGTCTGGATCCAATATGG	CDC42BPA	ENSG00000143776	-0.34718713018198816	[818,577]	[456,427]	-7	dCas9-KRAB	negative selection	5469674
227318398	227318421	1	-	27661255	K562	viability	GGCGCGAGCGCGAGAGGAGAGGG	CDC42BPA	ENSG00000143776	0.1555583411307132	[830,1031]	[898,762]	5	dCas9-KRAB	negative selection	5469675
227199571	227199594	1	-	27260156	BXPC3	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.2623586351978686	[1020]	[1233,1232,1095,1592]	6	hSpCas9	negative selection	5534715
227193910	227193933	1	+	27260156	BXPC3	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.05337710040978527	[266]	[285,290,240,344]	1	hSpCas9	negative selection	5534716
227193922	227193945	1	-	27260156	BXPC3	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.4583980507102214	[628]	[812,707,1072,1057]	8	hSpCas9	negative selection	5534717
227199553	227199576	1	+	27260156	BXPC3	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.02062574604218015	[1760]	[1815,1605,1825,2039]	0	hSpCas9	negative selection	5598992
227254128	227254151	1	+	27260156	BXPC3	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.19429518448701089	[315]	[291,368,426,439]	4	hSpCas9	negative selection	5598993
227254090	227254113	1	-	27260156	BXPC3	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.14445750855463846	[254]	[234,275,329,350]	3	hSpCas9	negative selection	5598994
227199571	227199594	1	-	27260156	A673	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.2727828578149549	[1020]	[1575,1297,1497,1569]	6	hSpCas9	negative selection	5655966
227193910	227193933	1	+	27260156	A673	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.21356296601332347	[266]	[350,418,353,357]	5	hSpCas9	negative selection	5655967
227193922	227193945	1	-	27260156	A673	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.4042397023330659	[628]	[1230,948,866,976]	8	hSpCas9	negative selection	5655968
227199553	227199576	1	+	27260156	A673	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.2224626592418888	[1760]	[2137,1674,1738,1730]	-5	hSpCas9	negative selection	5720243
227254128	227254151	1	+	27260156	A673	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.2852531795425375	[315]	[436,394,429,592]	6	hSpCas9	negative selection	5720244
227254090	227254113	1	-	27260156	A673	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.1989589822560015	[254]	[359,369,278,399]	5	hSpCas9	negative selection	5720245
227199571	227199594	1	-	27260156	A375	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.5883419325217563	[1020]	[1900,1732,1828,1704]	8	hSpCas9	negative selection	5777217
227193910	227193933	1	+	27260156	A375	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.22014628390874946	[266]	[388,408,322,339]	3	hSpCas9	negative selection	5777218
227193922	227193945	1	-	27260156	A375	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.05059244766590004	[628]	[493,841,916,792]	0	hSpCas9	negative selection	5777219
227199553	227199576	1	+	27260156	A375	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.016238264916803136	[1760]	[2285,2259,2009,1814]	0	hSpCas9	negative selection	5841494
227254128	227254151	1	+	27260156	A375	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.4467632165228378	[315]	[490,678,401,466]	6	hSpCas9	negative selection	5841495
227254090	227254113	1	-	27260156	A375	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.3647629462309896	[254]	[372,503,304,368]	5	hSpCas9	negative selection	5841496
227199571	227199594	1	-	27260156	COLO741	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.17268628613520232	[1020]	[1568,1430,1419]	3	hSpCas9	negative selection	5898468
227193910	227193933	1	+	27260156	COLO741	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	-0.0340895485398538	[266]	[351,365,285]	0	hSpCas9	negative selection	5898469
227193922	227193945	1	-	27260156	COLO741	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.29116929107351724	[628]	[1033,959,959]	6	hSpCas9	negative selection	5898470
227199553	227199576	1	+	27260156	COLO741	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.18129665633259662	[1760]	[1992,1828,2116]	-4	hSpCas9	negative selection	5962745
227254128	227254151	1	+	27260156	COLO741	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	-0.044091545945115884	[315]	[428,383,365]	-1	hSpCas9	negative selection	5962746
227254090	227254113	1	-	27260156	COLO741	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.26374852539607707	[254]	[455,302,416]	5	hSpCas9	negative selection	5962747
227199571	227199594	1	-	27260156	CAL120	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.36528708849043245	[1020]	[1899,1704,1348]	5	hSpCas9	negative selection	6019719
227193910	227193933	1	+	27260156	CAL120	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.34765474690741505	[266]	[311,431,505]	5	hSpCas9	negative selection	6019720
227193922	227193945	1	-	27260156	CAL120	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	-0.011350371305187568	[628]	[797,944,592]	0	hSpCas9	negative selection	6019721
227199553	227199576	1	+	27260156	CAL120	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.1827909482095713	[1760]	[2297,1827,1723]	-3	hSpCas9	negative selection	6083996
227254128	227254151	1	+	27260156	CAL120	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.39261718366969967	[315]	[734,533,315]	6	hSpCas9	negative selection	6083997
227254090	227254113	1	-	27260156	CAL120	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.06009593895184284	[254]	[442,194,295]	-1	hSpCas9	negative selection	6083998
227199571	227199594	1	-	27260156	CADOES1	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.4667138571915659	[1020]	[1625,1001,1325,1292]	7	hSpCas9	negative selection	6140970
227193910	227193933	1	+	27260156	CADOES1	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.11586490641933489	[266]	[255,327,236,254]	2	hSpCas9	negative selection	6140971
227193922	227193945	1	-	27260156	CADOES1	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.18105877433563683	[628]	[701,738,548,662]	3	hSpCas9	negative selection	6140972
227199553	227199576	1	+	27260156	CADOES1	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.013201790287154402	[1760]	[1583,1494,1760,1775]	0	hSpCas9	negative selection	6205247
227254128	227254151	1	+	27260156	CADOES1	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.5853385321191382	[315]	[296,522,410,536]	8	hSpCas9	negative selection	6205248
227254090	227254113	1	-	27260156	CADOES1	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.5681704167791392	[254]	[389,253,313,451]	8	hSpCas9	negative selection	6205249
227199571	227199594	1	-	27260156	EWS502	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.2532254062042676	[1020]	[1245,1106,1468,1347]	4	hSpCas9	negative selection	6262221
227193910	227193933	1	+	27260156	EWS502	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.5035007013571187	[266]	[267,353,501,504]	8	hSpCas9	negative selection	6262222
227193922	227193945	1	-	27260156	EWS502	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.370692471336543	[628]	[731,717,1010,1015]	6	hSpCas9	negative selection	6262223
227199553	227199576	1	+	27260156	EWS502	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.1398889186029475	[1760]	[2109,2070,1967,2054]	2	hSpCas9	negative selection	6326498
227254128	227254151	1	+	27260156	EWS502	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.3495469038226827	[315]	[305,387,470,565]	6	hSpCas9	negative selection	6326499
227254090	227254113	1	-	27260156	EWS502	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.3761959749954715	[254]	[497,255,294,335]	6	hSpCas9	negative selection	6326500
227199571	227199594	1	-	27260156	EW8	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.39787169460919847	[1020]	[1165,1302,860,1075]	7	hSpCas9	negative selection	6383472
227193910	227193933	1	+	27260156	EW8	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.2952813082380742	[266]	[387,233,192,271]	5	hSpCas9	negative selection	6383473
227193922	227193945	1	-	27260156	EW8	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.35072152792534433	[628]	[471,631,709,753]	6	hSpCas9	negative selection	6383474
227199553	227199576	1	+	27260156	EW8	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.02879143460840705	[1760]	[1616,1339,1271,1407]	0	hSpCas9	negative selection	6447749
227254128	227254151	1	+	27260156	EW8	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.41478489425865983	[315]	[502,311,260,319]	7	hSpCas9	negative selection	6447750
227254090	227254113	1	-	27260156	EW8	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.3313137435576258	[254]	[267,259,218,299]	6	hSpCas9	negative selection	6447751
227199571	227199594	1	-	27260156	CORL105	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.4149042922002939	[1020]	[1529,1387,1978,1538]	7	hSpCas9	negative selection	6504723
227193910	227193933	1	+	27260156	CORL105	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	-0.08529537990684921	[266]	[316,250,394,232]	-1	hSpCas9	negative selection	6504724
227193922	227193945	1	-	27260156	CORL105	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.3451852370070236	[628]	[803,930,970,1035]	6	hSpCas9	negative selection	6504725
227199553	227199576	1	+	27260156	CORL105	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.056078310586579194	[1760]	[1820,2129,1934,2028]	-1	hSpCas9	negative selection	6569000
227254128	227254151	1	+	27260156	CORL105	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.11152087608836542	[315]	[249,286,533,544]	2	hSpCas9	negative selection	6569001
227254090	227254113	1	-	27260156	CORL105	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.3513925391777881	[254]	[431,312,428,359]	6	hSpCas9	negative selection	6569002
227199571	227199594	1	-	27260156	HS294T	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.5274283939160347	[1020]	[546,585,541,606]	7	hSpCas9	negative selection	6625974
227193910	227193933	1	+	27260156	HS294T	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	-0.004820122351458234	[266]	[68,108,99,142]	0	hSpCas9	negative selection	6625975
227193922	227193945	1	-	27260156	HS294T	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.4043439820990275	[628]	[228,408,284,378]	5	hSpCas9	negative selection	6625976
227199553	227199576	1	+	27260156	HS294T	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.23279433163043928	[1760]	[562,869,777,1048]	3	hSpCas9	negative selection	6690251
227254128	227254151	1	+	27260156	HS294T	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	-0.19780926645023145	[315]	[97,86,76,176]	-3	hSpCas9	negative selection	6690252
227254090	227254113	1	-	27260156	HS294T	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.26270117568177276	[254]	[104,98,120,155]	3	hSpCas9	negative selection	6690253
227199571	227199594	1	-	27260156	HCC44	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.4465503980849874	[1020]	[1553,1457,1809,1516]	7	hSpCas9	negative selection	6747225
227193910	227193933	1	+	27260156	HCC44	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.12590338861080286	[266]	[278,238,600,253]	2	hSpCas9	negative selection	6747226
227193922	227193945	1	-	27260156	HCC44	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.24459405935895634	[628]	[1133,513,1090,744]	4	hSpCas9	negative selection	6747227
227199553	227199576	1	+	27260156	HCC44	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.01189836668649824	[1760]	[2194,2099,1905,1683]	0	hSpCas9	negative selection	6811502
227254128	227254151	1	+	27260156	HCC44	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.35373061909283837	[315]	[550,376,802,180]	6	hSpCas9	negative selection	6811503
227254090	227254113	1	-	27260156	HCC44	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.621036654479405	[254]	[382,556,531,296]	8	hSpCas9	negative selection	6811504
227199571	227199594	1	-	27260156	G402	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.5858417960216176	[1020]	[1883,1424,1751,2362]	7	hSpCas9	negative selection	6868476
227193910	227193933	1	+	27260156	G402	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.32253298220693405	[266]	[552,468,314,319]	4	hSpCas9	negative selection	6868477
227193922	227193945	1	-	27260156	G402	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.6607792926064346	[628]	[928,1279,443,2113]	7	hSpCas9	negative selection	6868478
227199553	227199576	1	+	27260156	G402	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.20631691470367208	[1760]	[3267,2196,1924,2607]	2	hSpCas9	negative selection	6932753
227254128	227254151	1	+	27260156	G402	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.7703494839727365	[315]	[324,1072,669,541]	8	hSpCas9	negative selection	6932754
227254090	227254113	1	-	27260156	G402	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.6231226030815946	[254]	[648,436,495,360]	7	hSpCas9	negative selection	6932755
227199571	227199594	1	-	27260156	L33	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.23531399943443576	[1020]	[1137,471,750,1322]	5	hSpCas9	negative selection	6989727
227193910	227193933	1	+	27260156	L33	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.3525826176124326	[266]	[291,150,244,314]	7	hSpCas9	negative selection	6989728
227193922	227193945	1	-	27260156	L33	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.2862122274862244	[628]	[693,267,592,778]	6	hSpCas9	negative selection	6989729
227199553	227199576	1	+	27260156	L33	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.01461726076748704	[1760]	[1654,735,1169,1805]	0	hSpCas9	negative selection	7054004
227254128	227254151	1	+	27260156	L33	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.33682657233692065	[315]	[436,177,226,362]	7	hSpCas9	negative selection	7054005
227254090	227254113	1	-	27260156	L33	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.45738331556126993	[254]	[316,165,202,355]	8	hSpCas9	negative selection	7054006
227199571	227199594	1	-	27260156	K562	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.413779971161659	[1020]	[919,1851,803,1251]	5	hSpCas9	negative selection	7110978
227193910	227193933	1	+	27260156	K562	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.041177127871767194	[266]	[381,112,167,307]	0	hSpCas9	negative selection	7110979
227193922	227193945	1	-	27260156	K562	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	-0.02747154601056251	[628]	[491,439,489,733]	0	hSpCas9	negative selection	7110980
227199553	227199576	1	+	27260156	K562	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.28078867990779166	[1760]	[1600,2096,1889,1974]	3	hSpCas9	negative selection	7175255
227254128	227254151	1	+	27260156	K562	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	-0.08344603274612417	[315]	[367,447,139,134]	-1	hSpCas9	negative selection	7175256
227254090	227254113	1	-	27260156	K562	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.31454897586740127	[254]	[316,370,321,138]	4	hSpCas9	negative selection	7175257
227199571	227199594	1	-	27260156	HT29	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.4667675644572231	[1020]	[1712,1862,1721,1579]	8	hSpCas9	negative selection	7232229
227193910	227193933	1	+	27260156	HT29	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.319869712738339	[266]	[389,469,392,372]	6	hSpCas9	negative selection	7232230
227193922	227193945	1	-	27260156	HT29	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.33122424862723215	[628]	[1175,975,928,797]	6	hSpCas9	negative selection	7232231
227199553	227199576	1	+	27260156	HT29	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.019838535060329843	[1760]	[2588,2068,2012,1827]	0	hSpCas9	negative selection	7296506
227254128	227254151	1	+	27260156	HT29	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.21557273534898708	[315]	[573,452,404,368]	4	hSpCas9	negative selection	7296507
227254090	227254113	1	-	27260156	HT29	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.656340894788062	[254]	[523,564,391,479]	9	hSpCas9	negative selection	7296508
227199571	227199594	1	-	27260156	MHHES1	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.38514790925005804	[1020]	[1623,2053,1361,1097]	7	hSpCas9	negative selection	7353480
227193910	227193933	1	+	27260156	MHHES1	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.07557891859615384	[266]	[309,563,208,222]	1	hSpCas9	negative selection	7353481
227193922	227193945	1	-	27260156	MHHES1	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	-0.00626731983840223	[628]	[892,792,550,618]	0	hSpCas9	negative selection	7353482
227199553	227199576	1	+	27260156	MHHES1	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.0939898915236761	[1760]	[2249,2116,1688,1492]	-2	hSpCas9	negative selection	7417757
227254128	227254151	1	+	27260156	MHHES1	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.3883109574746342	[315]	[334,512,518,472]	7	hSpCas9	negative selection	7417758
227254090	227254113	1	-	27260156	MHHES1	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.5725778420421286	[254]	[461,427,478,351]	8	hSpCas9	negative selection	7417759
227199571	227199594	1	-	27260156	MEWO	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.6719140504135079	[1020]	[2611,976,1189]	9	hSpCas9	negative selection	7474731
227193910	227193933	1	+	27260156	MEWO	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.04220159493549047	[266]	[285,287,202]	0	hSpCas9	negative selection	7474732
227193922	227193945	1	-	27260156	MEWO	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.30269860617313277	[628]	[803,626,761]	6	hSpCas9	negative selection	7474733
227199553	227199576	1	+	27260156	MEWO	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.13037646038649986	[1760]	[1805,1391,1375]	-3	hSpCas9	negative selection	7539008
227254128	227254151	1	+	27260156	MEWO	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.35241892196297425	[315]	[487,306,358]	7	hSpCas9	negative selection	7539009
227254090	227254113	1	-	27260156	MEWO	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.03425501471183734	[254]	[198,289,202]	0	hSpCas9	negative selection	7539010
227199571	227199594	1	-	27260156	LNCAPCLONEFGC	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.5678627674530665	[1020]	[1258,1379,1636,1247]	8	hSpCas9	negative selection	7595982
227193910	227193933	1	+	27260156	LNCAPCLONEFGC	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.4353767968128816	[266]	[255,408,407,242]	6	hSpCas9	negative selection	7595983
227193922	227193945	1	-	27260156	LNCAPCLONEFGC	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.04250917627800482	[628]	[451,565,809,555]	0	hSpCas9	negative selection	7595984
227199553	227199576	1	+	27260156	LNCAPCLONEFGC	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.014851418426240048	[1760]	[1442,1379,1846,1699]	0	hSpCas9	negative selection	7660259
227254128	227254151	1	+	27260156	LNCAPCLONEFGC	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.2570532018208834	[315]	[310,312,310,430]	4	hSpCas9	negative selection	7660260
227254090	227254113	1	-	27260156	LNCAPCLONEFGC	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.3530578860116159	[254]	[196,304,232,436]	5	hSpCas9	negative selection	7660261
227199571	227199594	1	-	27260156	PANC0327	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.3039398560554081	[1020]	[1319,1168,907,1090]	4	hSpCas9	negative selection	7717233
227193910	227193933	1	+	27260156	PANC0327	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.1727386756490732	[266]	[469,179,158,287]	2	hSpCas9	negative selection	7717234
227193922	227193945	1	-	27260156	PANC0327	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.5891235863690891	[628]	[607,740,1064,941]	8	hSpCas9	negative selection	7717235
227199553	227199576	1	+	27260156	PANC0327	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.09402181173320745	[1760]	[1868,1436,1907,1510]	1	hSpCas9	negative selection	7781510
227254128	227254151	1	+	27260156	PANC0327	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.4861473364493207	[315]	[393,226,387,584]	7	hSpCas9	negative selection	7781511
227254090	227254113	1	-	27260156	PANC0327	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.37139692880360287	[254]	[247,426,250,224]	5	hSpCas9	negative selection	7781512
227199571	227199594	1	-	27260156	NCIH2009	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.4241583717580655	[1020]	[2215,1616,1970]	6	hSpCas9	negative selection	7838484
227193910	227193933	1	+	27260156	NCIH2009	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.1827517472492004	[266]	[377,288,595]	2	hSpCas9	negative selection	7838485
227193922	227193945	1	-	27260156	NCIH2009	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.3582066779125341	[628]	[1110,822,1445]	5	hSpCas9	negative selection	7838486
227199553	227199576	1	+	27260156	NCIH2009	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.18554147113779873	[1760]	[3363,2704,2433]	2	hSpCas9	negative selection	7902761
227254128	227254151	1	+	27260156	NCIH2009	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.4319602700216567	[315]	[591,546,646]	6	hSpCas9	negative selection	7902762
227254090	227254113	1	-	27260156	NCIH2009	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.8113954376637074	[254]	[617,525,730]	9	hSpCas9	negative selection	7902763
227199571	227199594	1	-	27260156	NCIH1373	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.7346760088746447	[1020]	[1964,1837,1871,512]	7	hSpCas9	negative selection	7959735
227193910	227193933	1	+	27260156	NCIH1373	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.45473027235834274	[266]	[351,646,344,65]	4	hSpCas9	negative selection	7959736
227193922	227193945	1	-	27260156	NCIH1373	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	-0.17066284668772225	[628]	[492,465,646,238]	-2	hSpCas9	negative selection	7959737
227199553	227199576	1	+	27260156	NCIH1373	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.4523704543651945	[1760]	[2608,2746,2843,671]	4	hSpCas9	negative selection	8024012
227254128	227254151	1	+	27260156	NCIH1373	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.8085982137456216	[315]	[792,531,566,163]	7	hSpCas9	negative selection	8024013
227254090	227254113	1	-	27260156	NCIH1373	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.8723006824478827	[254]	[884,278,428,153]	8	hSpCas9	negative selection	8024014
227199571	227199594	1	-	27260156	PATU8902	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.9703552731849514	[1020]	[2928,3188,1952,3331]	9	hSpCas9	negative selection	8080986
227193910	227193933	1	+	27260156	PATU8902	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.9113006196047556	[266]	[743,858,163,1226]	8	hSpCas9	negative selection	8080987
227193922	227193945	1	-	27260156	PATU8902	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.12971548548365514	[628]	[853,836,980,1174]	1	hSpCas9	negative selection	8080988
227199553	227199576	1	+	27260156	PATU8902	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.18941224123679845	[1760]	[2495,2316,2598,3942]	2	hSpCas9	negative selection	8145263
227254128	227254151	1	+	27260156	PATU8902	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.8877613576325591	[315]	[1132,828,481,898]	8	hSpCas9	negative selection	8145264
227254090	227254113	1	-	27260156	PATU8902	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	1.1250329092290137	[254]	[353,836,1039,800]	9	hSpCas9	negative selection	8145265
227199571	227199594	1	-	27260156	PANC1	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.3408153274894197	[1020]	[1101,1198,1112,1039]	5	hSpCas9	negative selection	8202237
227193910	227193933	1	+	27260156	PANC1	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	-0.5409335770492447	[266]	[183,210,113,132]	-7	hSpCas9	negative selection	8202238
227193922	227193945	1	-	27260156	PANC1	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.46344768456251845	[628]	[723,766,887,615]	7	hSpCas9	negative selection	8202239
227199553	227199576	1	+	27260156	PANC1	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.12397770740848268	[1760]	[1240,1319,1475,1467]	-2	hSpCas9	negative selection	8266514
227254128	227254151	1	+	27260156	PANC1	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.4546174288987304	[315]	[371,439,429,270]	7	hSpCas9	negative selection	8266515
227254090	227254113	1	-	27260156	PANC1	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.10829630789323275	[254]	[267,236,207,227]	1	hSpCas9	negative selection	8266516
227199571	227199594	1	-	27260156	PANC0813	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.43511888475418403	[1020]	[1974,1329,1709,1507]	7	hSpCas9	negative selection	8323488
227193910	227193933	1	+	27260156	PANC0813	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.4536940843171018	[266]	[462,655,288,317]	7	hSpCas9	negative selection	8323489
227193922	227193945	1	-	27260156	PANC0813	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.7039174619767834	[628]	[1292,1090,1119,1309]	9	hSpCas9	negative selection	8323490
227199553	227199576	1	+	27260156	PANC0813	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.1367915008921896	[1760]	[2715,2214,2072,2136]	2	hSpCas9	negative selection	8387765
227254128	227254151	1	+	27260156	PANC0813	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.2424450145830791	[315]	[363,540,377,463]	4	hSpCas9	negative selection	8387766
227254090	227254113	1	-	27260156	PANC0813	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.8904562828019007	[254]	[470,563,490,678]	9	hSpCas9	negative selection	8387767
227199571	227199594	1	-	27260156	RDES	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.4270824235017321	[1020]	[1242,1419,1834,1919]	6	hSpCas9	negative selection	8444739
227193910	227193933	1	+	27260156	RDES	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.18371110671450686	[266]	[305,354,322,417]	3	hSpCas9	negative selection	8444740
227193922	227193945	1	-	27260156	RDES	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.020467655111159444	[628]	[610,703,698,960]	0	hSpCas9	negative selection	8444741
227199553	227199576	1	+	27260156	RDES	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.08005858805123767	[1760]	[1579,1940,2186,1986]	-1	hSpCas9	negative selection	8509016
227254128	227254151	1	+	27260156	RDES	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.40544991320953816	[315]	[304,568,513,567]	6	hSpCas9	negative selection	8509017
227254090	227254113	1	-	27260156	RDES	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.0824859267074699	[254]	[281,264,311,396]	1	hSpCas9	negative selection	8509018
227199571	227199594	1	-	27260156	PC3	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.1691843745148962	[1020]	[681,1067,2153,1168]	4	hSpCas9	negative selection	8565990
227193910	227193933	1	+	27260156	PC3	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.08029957080579742	[266]	[152,290,513,289]	1	hSpCas9	negative selection	8565991
227193922	227193945	1	-	27260156	PC3	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.17511989379751342	[628]	[402,706,1452,625]	4	hSpCas9	negative selection	8565992
227199553	227199576	1	+	27260156	PC3	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.21898535474275316	[1760]	[961,1576,2675,1350]	-5	hSpCas9	negative selection	8630267
227254128	227254151	1	+	27260156	PC3	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.2572292655067745	[315]	[269,443,574,290]	5	hSpCas9	negative selection	8630268
227254090	227254113	1	-	27260156	PC3	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.14084779391372704	[254]	[207,174,368,204]	-3	hSpCas9	negative selection	8630269
227199571	227199594	1	-	27260156	PATU8988T	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.24585892232894024	[1020]	[1017,1382,1039,1267]	4	hSpCas9	negative selection	8687241
227193910	227193933	1	+	27260156	PATU8988T	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.10567688564492028	[266]	[188,239,458,210]	1	hSpCas9	negative selection	8687242
227193922	227193945	1	-	27260156	PATU8988T	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.5690891029378793	[628]	[1190,730,862,797]	8	hSpCas9	negative selection	8687243
227199553	227199576	1	+	27260156	PATU8988T	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.007723861744982186	[1760]	[1498,1607,1707,1968]	0	hSpCas9	negative selection	8751518
227254128	227254151	1	+	27260156	PATU8988T	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.3615361993409849	[315]	[419,381,280,494]	6	hSpCas9	negative selection	8751519
227254090	227254113	1	-	27260156	PATU8988T	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.022175770451588916	[254]	[203,243,208,351]	0	hSpCas9	negative selection	8751520
227199571	227199594	1	-	27260156	T47D	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.273785095710384	[1020]	[1380,1371,1565,1435]	6	hSpCas9	negative selection	8808492
227193910	227193933	1	+	27260156	T47D	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.2253865035046565	[266]	[395,293,385,384]	5	hSpCas9	negative selection	8808493
227193922	227193945	1	-	27260156	T47D	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.19302267768451503	[628]	[877,706,742,1041]	4	hSpCas9	negative selection	8808494
227199553	227199576	1	+	27260156	T47D	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.09373744256633221	[1760]	[1859,1701,2087,2059]	-2	hSpCas9	negative selection	8872769
227254128	227254151	1	+	27260156	T47D	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.2486682133354769	[315]	[441,345,345,630]	5	hSpCas9	negative selection	8872770
227254090	227254113	1	-	27260156	T47D	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.2925964901115594	[254]	[419,335,366,333]	6	hSpCas9	negative selection	8872771
227199571	227199594	1	-	27260156	SU8686	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.45667794537494544	[1020]	[1344,1262,1345,1655]	7	hSpCas9	negative selection	8929743
227193910	227193933	1	+	27260156	SU8686	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.4369665535270602	[266]	[258,354,390,453]	7	hSpCas9	negative selection	8929744
227193922	227193945	1	-	27260156	SU8686	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.35888531101081983	[628]	[799,709,849,854]	6	hSpCas9	negative selection	8929745
227199553	227199576	1	+	27260156	SU8686	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.1973204600871039	[1760]	[1553,1739,2256,2636]	3	hSpCas9	negative selection	8994020
227254128	227254151	1	+	27260156	SU8686	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.2613207594043847	[315]	[286,322,507,406]	4	hSpCas9	negative selection	8994021
227254090	227254113	1	-	27260156	SU8686	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.7706187444176704	[254]	[475,341,485,424]	9	hSpCas9	negative selection	8994022
227199571	227199594	1	-	27260156	SKES1	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.34715064243748506	[1020]	[1385,1354,1402,1069]	7	hSpCas9	negative selection	9050994
227193910	227193933	1	+	27260156	SKES1	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	-0.05110981394462777	[266]	[338,279,196,227]	-1	hSpCas9	negative selection	9050995
227193922	227193945	1	-	27260156	SKES1	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.22726095989589118	[628]	[742,820,696,686]	5	hSpCas9	negative selection	9050996
227199553	227199576	1	+	27260156	SKES1	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.0764458458429067	[1760]	[2003,1777,1783,1195]	-2	hSpCas9	negative selection	9115271
227254128	227254151	1	+	27260156	SKES1	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.301330931911804	[315]	[419,515,316,324]	6	hSpCas9	negative selection	9115272
227254090	227254113	1	-	27260156	SKES1	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.169678898035044	[254]	[293,309,288,255]	3	hSpCas9	negative selection	9115273
227199571	227199594	1	-	27260156	TOV112D	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.29224676258952154	[1020]	[1580,1232,974,1240]	5	hSpCas9	negative selection	9172245
227193910	227193933	1	+	27260156	TOV112D	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.08901911701387255	[266]	[271,307,276,284]	1	hSpCas9	negative selection	9172246
227193922	227193945	1	-	27260156	TOV112D	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.3136873765702917	[628]	[907,910,618,735]	6	hSpCas9	negative selection	9172247
227199553	227199576	1	+	27260156	TOV112D	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.044537967991026495	[1760]	[1929,2202,1444,1407]	-1	hSpCas9	negative selection	9236522
227254128	227254151	1	+	27260156	TOV112D	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.06853845489599075	[315]	[236,558,322,257]	1	hSpCas9	negative selection	9236523
227254090	227254113	1	-	27260156	TOV112D	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.08354138227001862	[254]	[217,379,216,288]	1	hSpCas9	negative selection	9236524
227199571	227199594	1	-	27260156	TC71	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.04686844163177173	[1020]	[1171,1026,1133,1191]	1	hSpCas9	negative selection	9293496
227193910	227193933	1	+	27260156	TC71	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	-0.0777027042654107	[266]	[196,284,315,287]	-2	hSpCas9	negative selection	9293497
227193922	227193945	1	-	27260156	TC71	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	0.28946242402757566	[628]	[858,819,826,786]	7	hSpCas9	negative selection	9293498
227199553	227199576	1	+	27260156	TC71	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	0.001929298745015462	[1760]	[2148,1774,1572,2079]	0	hSpCas9	negative selection	9357773
227254128	227254151	1	+	27260156	TC71	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.31335817534794	[315]	[379,470,350,488]	7	hSpCas9	negative selection	9357774
227254090	227254113	1	-	27260156	TC71	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	-0.12281144350558815	[254]	[227,265,272,235]	-3	hSpCas9	negative selection	9357775
227199571	227199594	1	-	27260156	TC32	viability	AACCTTGCACTATGCTTTCCAGG	CDC42BPA	ENSG00000143776	0.1368133041116124	[1020]	[958,758,1558,1094]	2	hSpCas9	negative selection	9414747
227193910	227193933	1	+	27260156	TC32	viability	CAACATAATAATCCATAACCAGG	CDC42BPA	ENSG00000143776	0.3513608768933759	[266]	[222,239,631,260]	6	hSpCas9	negative selection	9414748
227193922	227193945	1	-	27260156	TC32	viability	TCATTCACAGTACCTGGTTATGG	CDC42BPA	ENSG00000143776	-0.003983999369778113	[628]	[490,399,869,702]	0	hSpCas9	negative selection	9414749
227199553	227199576	1	+	27260156	TC32	viability	TTACTAAGTTATTGTCATCCTGG	CDC42BPA	ENSG00000143776	-0.11427020639328211	[1760]	[1345,1248,1885,1744]	-2	hSpCas9	negative selection	9479024
227254128	227254151	1	+	27260156	TC32	viability	TGTTTCACTTTAGAAGTAAATGG	CDC42BPA	ENSG00000143776	0.3388771193329373	[315]	[306,279,450,507]	6	hSpCas9	negative selection	9479025
227254090	227254113	1	-	27260156	TC32	viability	AGAAGACTTTGAAATATTAAAGG	CDC42BPA	ENSG00000143776	0.6183539960200843	[254]	[283,335,444,422]	9	hSpCas9	negative selection	9479026
227112375	227112398	1	-	27869803	HPAFII	viability after 27 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.23869191330057937	[498]	[266,344,NaN]	2	hSpCas9	negative selection	9532428
227112742	227112765	1	-	27869803	HPAFII	viability after 27 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-0.2932230956097416	[384]	[210,126,NaN]	-2	hSpCas9	negative selection	9532429
227139704	227139727	1	-	27869803	HPAFII	viability after 27 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.5217298759432502	[184]	[155,125,NaN]	4	hSpCas9	negative selection	9532430
227145700	227145723	1	+	27869803	HPAFII	viability after 27 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-1.0564021482869284	[113]	[24,31,NaN]	-6	hSpCas9	negative selection	9532431
227147489	227147512	1	-	27869803	HPAFII	viability after 27 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	1.3235091307068427	[170]	[134,299,NaN]	9	hSpCas9	negative selection	9532432
227317115	227317138	1	-	27869803	HPAFII	viability after 27 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	1.201010031571876	[131]	[248,84,NaN]	8	hSpCas9	negative selection	9532433
227112375	227112398	1	-	27869803	HPAFII	viability after 15 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	-0.09681522551948984	[498]	[839,290,NaN]	-1	hSpCas9	negative selection	9614877
227112742	227112765	1	-	27869803	HPAFII	viability after 15 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-0.22180373087326616	[384]	[413,317,NaN]	-3	hSpCas9	negative selection	9614878
227139704	227139727	1	-	27869803	HPAFII	viability after 15 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	1.0347624705943343	[184]	[386,419,NaN]	9	hSpCas9	negative selection	9614879
227145700	227145723	1	+	27869803	HPAFII	viability after 15 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-0.5748740398656627	[113]	[109,64,NaN]	-6	hSpCas9	negative selection	9614880
227147489	227147512	1	-	27869803	HPAFII	viability after 15 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	1.0808687880061125	[170]	[553,285,NaN]	9	hSpCas9	negative selection	9614881
227317115	227317138	1	-	27869803	HPAFII	viability after 15 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.04647544292466732	[131]	[238,88,NaN]	0	hSpCas9	negative selection	9614882
227112375	227112398	1	-	27869803	ASPC1	viability after 36 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.3888376802973645	[875]	[424,529,275]	4	hSpCas9	negative selection	9697326
227112742	227112765	1	-	27869803	ASPC1	viability after 36 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.9730170467728574	[754]	[296,396,761]	8	hSpCas9	negative selection	9697327
227139704	227139727	1	-	27869803	ASPC1	viability after 36 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.9927530268382945	[441]	[329,579,70]	8	hSpCas9	negative selection	9697328
227145700	227145723	1	+	27869803	ASPC1	viability after 36 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	0.919238422881776	[369]	[316,40,351]	8	hSpCas9	negative selection	9697329
227147489	227147512	1	-	27869803	ASPC1	viability after 36 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	0.7361621414206924	[482]	[210,349,271]	7	hSpCas9	negative selection	9697330
227317115	227317138	1	-	27869803	ASPC1	viability after 36 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.8097857062829784	[366]	[559,37,134]	7	hSpCas9	negative selection	9697331
227112375	227112398	1	-	27869803	PATU8988S	viability after 35 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.024942967728253884	[887]	[310,416,NaN]	0	hSpCas9	negative selection	9779775
227112742	227112765	1	-	27869803	PATU8988S	viability after 35 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.46256956123411164	[648]	[441,277,NaN]	5	hSpCas9	negative selection	9779776
227139704	227139727	1	-	27869803	PATU8988S	viability after 35 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.18376277714874958	[434]	[196,200,NaN]	2	hSpCas9	negative selection	9779777
227145700	227145723	1	+	27869803	PATU8988S	viability after 35 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	0.3141744265829367	[113]	[93,19,NaN]	3	hSpCas9	negative selection	9779778
227147489	227147512	1	-	27869803	PATU8988S	viability after 35 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	-0.7092440973178384	[441]	[56,160,NaN]	-6	hSpCas9	negative selection	9779779
227317115	227317138	1	-	27869803	PATU8988S	viability after 35 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.38822978625632754	[391]	[262,149,NaN]	4	hSpCas9	negative selection	9779780
227112375	227112398	1	-	27869803	PATU8988S	viability after 31 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	-0.29928508351068794	[887]	[230,359,NaN]	-3	hSpCas9	negative selection	9862224
227112742	227112765	1	-	27869803	PATU8988S	viability after 31 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	0.27004636785502467	[648]	[381,222,NaN]	3	hSpCas9	negative selection	9862225
227139704	227139727	1	-	27869803	PATU8988S	viability after 31 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.09702087276721208	[434]	[181,189,NaN]	1	hSpCas9	negative selection	9862226
227145700	227145723	1	+	27869803	PATU8988S	viability after 31 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-0.20915819215600884	[113]	[48,26,NaN]	-2	hSpCas9	negative selection	9862227
227147489	227147512	1	-	27869803	PATU8988S	viability after 31 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	-0.6780547398068861	[441]	[81,145,NaN]	-6	hSpCas9	negative selection	9862228
227317115	227317138	1	-	27869803	PATU8988S	viability after 31 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	0.4791761374641815	[391]	[238,190,NaN]	6	hSpCas9	negative selection	9862229
227112375	227112398	1	-	27869803	HPAFII	viability after 35 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.5459430549990443	[498]	[349,389,NaN]	3	hSpCas9	negative selection	9944673
227112742	227112765	1	-	27869803	HPAFII	viability after 35 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-0.44054737140825406	[384]	[200,78,NaN]	-3	hSpCas9	negative selection	9944674
227139704	227139727	1	-	27869803	HPAFII	viability after 35 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.26319517124454456	[184]	[86,140,NaN]	1	hSpCas9	negative selection	9944675
227145700	227145723	1	+	27869803	HPAFII	viability after 35 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-1.5634997093903364	[113]	[11,27,NaN]	-7	hSpCas9	negative selection	9944676
227147489	227147512	1	-	27869803	HPAFII	viability after 35 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	1.2205266390237304	[170]	[133,277,NaN]	7	hSpCas9	negative selection	9944677
227317115	227317138	1	-	27869803	HPAFII	viability after 35 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	1.6249698296566273	[131]	[310,87,NaN]	9	hSpCas9	negative selection	9944678
227112375	227112398	1	-	27869803	HPAFII	viability after 31 days	CTGCTGAAGCATCTAAAGACAGG	CDC42BPA	ENSG00000143776	0.3318084645085826	[498]	[373,328,NaN]	2	hSpCas9	negative selection	10027122
227112742	227112765	1	-	27869803	HPAFII	viability after 31 days	TGTCCGAGATAAGGAAGAAGAGG	CDC42BPA	ENSG00000143776	-0.47802282112409644	[384]	[157,151,NaN]	-3	hSpCas9	negative selection	10027123
227139704	227139727	1	-	27869803	HPAFII	viability after 31 days	AGCTGTTTAAGAGTTACGGCTGG	CDC42BPA	ENSG00000143776	0.7650469562564044	[184]	[163,189,NaN]	5	hSpCas9	negative selection	10027124
227145700	227145723	1	+	27869803	HPAFII	viability after 31 days	GACACATCAGTCACTTGGGCTGG	CDC42BPA	ENSG00000143776	-0.945476606909839	[113]	[26,39,NaN]	-5	hSpCas9	negative selection	10027125
227147489	227147512	1	-	27869803	HPAFII	viability after 31 days	ATCCTTCAAGCCATGGAAGATGG	CDC42BPA	ENSG00000143776	1.0785684397973956	[170]	[161,246,NaN]	7	hSpCas9	negative selection	10027126
227317115	227317138	1	-	27869803	HPAFII	viability after 31 days	GACGGGCCCGCTCAGACCAATGG	CDC42BPA	ENSG00000143776	1.4824142545196257	[131]	[351,48,NaN]	9	hSpCas9	negative selection	10027127
227213135	227213158	1	-	28162770	P31FUJ	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.23332406679692694	[214]	[296]	2	hSpCas9	negative selection	10130028
227040153	227040176	1	+	28162770	P31FUJ	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	1.0532488541443872	[56]	[138]	9	hSpCas9	negative selection	10130029
227147455	227147478	1	-	28162770	P31FUJ	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	1.6608967222385345	[270]	[1006]	9	hSpCas9	negative selection	10130030
227074337	227074360	1	-	28162770	P31FUJ	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.17341144447745893	[122]	[162]	1	hSpCas9	negative selection	10130031
227034749	227034772	1	-	28162770	P31FUJ	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.37500081651279493	[276]	[250]	-3	hSpCas9	negative selection	10130032
227028710	227028733	1	-	28162770	P31FUJ	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	-0.02635132694695219	[38]	[44]	0	hSpCas9	negative selection	10130033
227254063	227254086	1	-	28162770	P31FUJ	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.686161223494715	[237]	[449]	7	hSpCas9	negative selection	10130034
227112320	227112343	1	-	28162770	P31FUJ	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.6836541548026083	[470]	[888]	7	hSpCas9	negative selection	10130035
227091975	227091998	1	-	28162770	P31FUJ	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	1.4054585224668266	[61]	[192]	9	hSpCas9	negative selection	10130036
227047978	227048001	1	+	28162770	P31FUJ	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.7352784617108694	[456]	[893]	8	hSpCas9	negative selection	10130037
227213135	227213158	1	-	28162770	TF1	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[382]	1	hSpCas9	negative selection	10299394
227040153	227040176	1	+	28162770	TF1	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10299395
227147455	227147478	1	-	28162770	TF1	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[409]	1	hSpCas9	negative selection	10299396
227074337	227074360	1	-	28162770	TF1	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10299397
227034749	227034772	1	-	28162770	TF1	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10299398
227028710	227028733	1	-	28162770	TF1	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10299399
227254063	227254086	1	-	28162770	TF1	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[212]	1	hSpCas9	negative selection	10299400
227112320	227112343	1	-	28162770	TF1	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[369]	1	hSpCas9	negative selection	10299401
227091975	227091998	1	-	28162770	TF1	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10299402
227047978	227048001	1	+	28162770	TF1	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10299403
227213135	227213158	1	-	28162770	SKM1	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.34583998891981765	[76]	[172]	3	hSpCas9	negative selection	10468760
227040153	227040176	1	+	28162770	SKM1	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	1.4510167963844105	[5]	[28]	9	hSpCas9	negative selection	10468761
227147455	227147478	1	-	28162770	SKM1	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	0.39350433772920235	[89]	[208]	4	hSpCas9	negative selection	10468762
227074337	227074360	1	-	28162770	SKM1	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.2368919910315632	[47]	[99]	2	hSpCas9	negative selection	10468763
227034749	227034772	1	-	28162770	SKM1	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-1.3041533931593863	[87]	[62]	-7	hSpCas9	negative selection	10468764
227028710	227028733	1	-	28162770	SKM1	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	0.6870119494658522	[12]	[36]	6	hSpCas9	negative selection	10468765
227254063	227254086	1	-	28162770	SKM1	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.2253040167563512	[44]	[92]	2	hSpCas9	negative selection	10468766
227112320	227112343	1	-	28162770	SKM1	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	1.7745024245818417	[82]	[501]	9	hSpCas9	negative selection	10468767
227091975	227091998	1	-	28162770	SKM1	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	0.1779983019779947	[16]	[33]	1	hSpCas9	negative selection	10468768
227047978	227048001	1	+	28162770	SKM1	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.11944611962288143	[87]	[168]	1	hSpCas9	negative selection	10468769
227213135	227213158	1	-	28162770	SKM1	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.34583998891981765	[76]	[172]	3	hSpCas9	negative selection	10638126
227040153	227040176	1	+	28162770	SKM1	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	1.4510167963844105	[5]	[28]	9	hSpCas9	negative selection	10638127
227147455	227147478	1	-	28162770	SKM1	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	0.39350433772920235	[89]	[208]	4	hSpCas9	negative selection	10638128
227074337	227074360	1	-	28162770	SKM1	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.2368919910315632	[47]	[99]	2	hSpCas9	negative selection	10638129
227034749	227034772	1	-	28162770	SKM1	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-1.3041533931593863	[87]	[62]	-7	hSpCas9	negative selection	10638130
227028710	227028733	1	-	28162770	SKM1	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	0.6870119494658522	[12]	[36]	6	hSpCas9	negative selection	10638131
227254063	227254086	1	-	28162770	SKM1	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.2253040167563512	[44]	[92]	2	hSpCas9	negative selection	10638132
227112320	227112343	1	-	28162770	SKM1	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	1.7745024245818417	[82]	[501]	9	hSpCas9	negative selection	10638133
227091975	227091998	1	-	28162770	SKM1	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	0.1779983019779947	[16]	[33]	1	hSpCas9	negative selection	10638134
227047978	227048001	1	+	28162770	SKM1	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.11944611962288143	[87]	[168]	1	hSpCas9	negative selection	10638135
227213135	227213158	1	-	28162770	PL21	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.7929642329834465	[182]	[137]	6	hSpCas9	negative selection	10807492
227040153	227040176	1	+	28162770	PL21	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	0.785102115210476	[15]	[11]	6	hSpCas9	negative selection	10807493
227147455	227147478	1	-	28162770	PL21	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	-0.09976217406804333	[324]	[131]	0	hSpCas9	negative selection	10807494
227074337	227074360	1	-	28162770	PL21	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.6421441613684333	[158]	[107]	5	hSpCas9	negative selection	10807495
227034749	227034772	1	-	28162770	PL21	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.2960939676375045	[267]	[94]	-2	hSpCas9	negative selection	10807496
227028710	227028733	1	-	28162770	PL21	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	-1.3578558386315667	[52]	[8]	-7	hSpCas9	negative selection	10807497
227254063	227254086	1	-	28162770	PL21	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.8804499917979575	[160]	[128]	7	hSpCas9	negative selection	10807498
227112320	227112343	1	-	28162770	PL21	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	1.1589169517628068	[354]	[344]	8	hSpCas9	negative selection	10807499
227091975	227091998	1	-	28162770	PL21	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	-1.89501761855102	[93]	[10]	-8	hSpCas9	negative selection	10807500
227047978	227048001	1	+	28162770	PL21	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.28977682697399665	[311]	[165]	2	hSpCas9	negative selection	10807501
227213135	227213158	1	-	28162770	P31FUJ	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.23332406679692694	[214]	[296]	2	hSpCas9	negative selection	10976858
227040153	227040176	1	+	28162770	P31FUJ	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	1.0532488541443872	[56]	[138]	9	hSpCas9	negative selection	10976859
227147455	227147478	1	-	28162770	P31FUJ	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	1.6608967222385345	[270]	[1006]	9	hSpCas9	negative selection	10976860
227074337	227074360	1	-	28162770	P31FUJ	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.17341144447745893	[122]	[162]	1	hSpCas9	negative selection	10976861
227034749	227034772	1	-	28162770	P31FUJ	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.37500081651279493	[276]	[250]	-3	hSpCas9	negative selection	10976862
227028710	227028733	1	-	28162770	P31FUJ	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	-0.02635132694695219	[38]	[44]	0	hSpCas9	negative selection	10976863
227254063	227254086	1	-	28162770	P31FUJ	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.686161223494715	[237]	[449]	7	hSpCas9	negative selection	10976864
227112320	227112343	1	-	28162770	P31FUJ	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.6836541548026083	[470]	[888]	7	hSpCas9	negative selection	10976865
227091975	227091998	1	-	28162770	P31FUJ	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	1.4054585224668266	[61]	[192]	9	hSpCas9	negative selection	10976866
227047978	227048001	1	+	28162770	P31FUJ	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.7352784617108694	[456]	[893]	8	hSpCas9	negative selection	10976867
227213135	227213158	1	-	28162770	OCIAML5	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.6726784070230525	[105]	[304]	6	hSpCas9	negative selection	11146224
227040153	227040176	1	+	28162770	OCIAML5	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	-2.147522454390168	[26]	[10]	-8	hSpCas9	negative selection	11146225
227147455	227147478	1	-	28162770	OCIAML5	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	0.19552288765426323	[163]	[338]	1	hSpCas9	negative selection	11146226
227074337	227074360	1	-	28162770	OCIAML5	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-0.9641769371855343	[106]	[98]	-6	hSpCas9	negative selection	11146227
227034749	227034772	1	-	28162770	OCIAML5	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-1.3854987709450712	[164]	[113]	-7	hSpCas9	negative selection	11146228
227028710	227028733	1	-	28162770	OCIAML5	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	1.0276391954182915	[24]	[91]	8	hSpCas9	negative selection	11146229
227254063	227254086	1	-	28162770	OCIAML5	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	-0.19824221199803652	[149]	[235]	-1	hSpCas9	negative selection	11146230
227112320	227112343	1	-	28162770	OCIAML5	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.6349508794451999	[258]	[725]	5	hSpCas9	negative selection	11146231
227091975	227091998	1	-	28162770	OCIAML5	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	1.2841991192270839	[52]	[232]	9	hSpCas9	negative selection	11146232
227047978	227048001	1	+	28162770	OCIAML5	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.15670363876373505	[245]	[494]	1	hSpCas9	negative selection	11146233
227213135	227213158	1	-	28162770	EOL1	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.44067139596369287	[371]	[265]	4	hSpCas9	negative selection	11315590
227040153	227040176	1	+	28162770	EOL1	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	1.8283324563112313	[30]	[57]	9	hSpCas9	negative selection	11315591
227147455	227147478	1	-	28162770	EOL1	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	1.381533452847349	[482]	[662]	9	hSpCas9	negative selection	11315592
227074337	227074360	1	-	28162770	EOL1	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-0.2893731336984614	[282]	[121]	-2	hSpCas9	negative selection	11315593
227034749	227034772	1	-	28162770	EOL1	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.3239682366969927	[612]	[257]	-2	hSpCas9	negative selection	11315594
227028710	227028733	1	-	28162770	EOL1	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	1.5095102722916907	[69]	[104]	9	hSpCas9	negative selection	11315595
227254063	227254086	1	-	28162770	EOL1	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.10709225954396062	[214]	[121]	1	hSpCas9	negative selection	11315596
227112320	227112343	1	-	28162770	EOL1	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.6410311045348577	[453]	[372]	6	hSpCas9	negative selection	11315597
227091975	227091998	1	-	28162770	EOL1	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	0.67300900457457	[74]	[62]	6	hSpCas9	negative selection	11315598
227047978	227048001	1	+	28162770	EOL1	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	-0.1890472602714252	[382]	[176]	-1	hSpCas9	negative selection	11315599
227213135	227213158	1	-	28162770	MOLM13	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.6570056480067283	[306]	[349]	5	hSpCas9	negative selection	11484956
227040153	227040176	1	+	28162770	MOLM13	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	-0.11707311917657748	[35]	[23]	0	hSpCas9	negative selection	11484957
227147455	227147478	1	-	28162770	MOLM13	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	1.8573917887162854	[341]	[895]	9	hSpCas9	negative selection	11484958
227074337	227074360	1	-	28162770	MOLM13	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-0.08850396697980643	[274]	[186]	0	hSpCas9	negative selection	11484959
227034749	227034772	1	-	28162770	MOLM13	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.18472694288538893	[381]	[242]	-1	hSpCas9	negative selection	11484960
227028710	227028733	1	-	28162770	MOLM13	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	-1.3988440875919568	[61]	[16]	-6	hSpCas9	negative selection	11484961
227254063	227254086	1	-	28162770	MOLM13	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	-0.4161913311558538	[250]	[135]	-2	hSpCas9	negative selection	11484962
227112320	227112343	1	-	28162770	MOLM13	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.6328055316990194	[544]	[610]	5	hSpCas9	negative selection	11484963
227091975	227091998	1	-	28162770	MOLM13	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	-0.19724346786056057	[110]	[69]	-1	hSpCas9	negative selection	11484964
227047978	227048001	1	+	28162770	MOLM13	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.019531809065708505	[437]	[320]	0	hSpCas9	negative selection	11484965
227213135	227213158	1	-	28162770	HEL	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.08233343552317954	[232]	[157]	0	hSpCas9	negative selection	11654322
227040153	227040176	1	+	28162770	HEL	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	-1.579653589336091	[27]	[5]	-7	hSpCas9	negative selection	11654323
227147455	227147478	1	-	28162770	HEL	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	0.9662257547442812	[369]	[462]	8	hSpCas9	negative selection	11654324
227074337	227074360	1	-	28162770	HEL	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-0.26611327994144773	[275]	[146]	-2	hSpCas9	negative selection	11654325
227034749	227034772	1	-	28162770	HEL	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.7069499560876189	[445]	[174]	-4	hSpCas9	negative selection	11654326
227028710	227028733	1	-	28162770	HEL	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	0.9954104503188274	[64]	[82]	8	hSpCas9	negative selection	11654327
227254063	227254086	1	-	28162770	HEL	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.5384021721856214	[171]	[159]	4	hSpCas9	negative selection	11654328
227112320	227112343	1	-	28162770	HEL	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.05001571525045134	[465]	[308]	0	hSpCas9	negative selection	11654329
227091975	227091998	1	-	28162770	HEL	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	-0.06579835383933186	[66]	[40]	0	hSpCas9	negative selection	11654330
227047978	227048001	1	+	28162770	HEL	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.5874889714348948	[345]	[332]	5	hSpCas9	negative selection	11654331
227213135	227213158	1	-	28162770	MV411	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.996305234005273	[168]	[283]	8	hSpCas9	negative selection	11823688
227040153	227040176	1	+	28162770	MV411	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	-0.8050298691113602	[55]	[26]	-5	hSpCas9	negative selection	11823689
227147455	227147478	1	-	28162770	MV411	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	1.6247846145429823	[285]	[742]	9	hSpCas9	negative selection	11823690
227074337	227074360	1	-	28162770	MV411	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	-1.0618905073249534	[170]	[68]	-6	hSpCas9	negative selection	11823691
227034749	227034772	1	-	28162770	MV411	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.3850768794184001	[292]	[188]	-3	hSpCas9	negative selection	11823692
227028710	227028733	1	-	28162770	MV411	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	-0.3941084783047484	[38]	[24]	-3	hSpCas9	negative selection	11823693
227254063	227254086	1	-	28162770	MV411	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.4183221099863604	[166]	[187]	4	hSpCas9	negative selection	11823694
227112320	227112343	1	-	28162770	MV411	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	-0.289871974346965	[401]	[276]	-2	hSpCas9	negative selection	11823695
227091975	227091998	1	-	28162770	MV411	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	-0.8207339518588039	[64]	[30]	-5	hSpCas9	negative selection	11823696
227047978	227048001	1	+	28162770	MV411	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	-0.08072249781610163	[289]	[230]	0	hSpCas9	negative selection	11823697
227213135	227213158	1	-	28162770	MONOMAC1	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.36632339917639145	[156]	[231]	3	hSpCas9	negative selection	11993054
227040153	227040176	1	+	28162770	MONOMAC1	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	0.6103180749980504	[11]	[20]	6	hSpCas9	negative selection	11993055
227147455	227147478	1	-	28162770	MONOMAC1	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	0.6033541272482859	[177]	[309]	6	hSpCas9	negative selection	11993056
227074337	227074360	1	-	28162770	MONOMAC1	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	2.6645796687845245	[81]	[595]	9	hSpCas9	negative selection	11993057
227034749	227034772	1	-	28162770	MONOMAC1	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.39282391181383197	[196]	[171]	-3	hSpCas9	negative selection	11993058
227028710	227028733	1	-	28162770	MONOMAC1	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	0.8029631529404466	[22]	[45]	7	hSpCas9	negative selection	11993059
227254063	227254086	1	-	28162770	MONOMAC1	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	0.6949804720674346	[103]	[192]	6	hSpCas9	negative selection	11993060
227112320	227112343	1	-	28162770	MONOMAC1	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.19889182927158555	[208]	[274]	2	hSpCas9	negative selection	11993061
227091975	227091998	1	-	28162770	MONOMAC1	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	0.7141538859825904	[66]	[125]	6	hSpCas9	negative selection	11993062
227047978	227048001	1	+	28162770	MONOMAC1	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	-0.3385092730124343	[181]	[164]	-3	hSpCas9	negative selection	11993063
227213135	227213158	1	-	28162770	OCIAML2	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	0.21009165828442575	[33]	[217]	2	hSpCas9	negative selection	12162420
227040153	227040176	1	+	28162770	OCIAML2	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	0.9216875975365992	[1]	[20]	8	hSpCas9	negative selection	12162421
227147455	227147478	1	-	28162770	OCIAML2	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	0.8407031544060021	[40]	[406]	7	hSpCas9	negative selection	12162422
227074337	227074360	1	-	28162770	OCIAML2	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.03892527282097262	[35]	[204]	0	hSpCas9	negative selection	12162423
227034749	227034772	1	-	28162770	OCIAML2	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	-0.4237632202041869	[52]	[218]	-3	hSpCas9	negative selection	12162424
227028710	227028733	1	-	28162770	OCIAML2	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	0.3622601889225805	[7]	[56]	3	hSpCas9	negative selection	12162425
227254063	227254086	1	-	28162770	OCIAML2	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	1.1587267948374484	[23]	[296]	9	hSpCas9	negative selection	12162426
227112320	227112343	1	-	28162770	OCIAML2	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.6391240266175515	[67]	[586]	6	hSpCas9	negative selection	12162427
227091975	227091998	1	-	28162770	OCIAML2	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	0.21587070194105729	[15]	[102]	2	hSpCas9	negative selection	12162428
227047978	227048001	1	+	28162770	OCIAML2	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	0.46555507716039524	[51]	[397]	4	hSpCas9	negative selection	12162429
227213135	227213158	1	-	28162770	OCIAML3	viability	GGAAATGCTGAAAAGAGCTGAGG	CDC42BPA	ENSG00000143776	-0.3901353069585131	[55]	[128]	-3	hSpCas9	negative selection	12331786
227040153	227040176	1	+	28162770	OCIAML3	viability	TATTAAACCCACCATCAAGGAGG	CDC42BPA	ENSG00000143776	-1.231437560939455	[13]	[17]	-7	hSpCas9	negative selection	12331787
227147455	227147478	1	-	28162770	OCIAML3	viability	ATGGACCTGAATGTGACTGGTGG	CDC42BPA	ENSG00000143776	-0.07116685151080449	[86]	[249]	0	hSpCas9	negative selection	12331788
227074337	227074360	1	-	28162770	OCIAML3	viability	GCGATGAAAAGGATGCACGAGGG	CDC42BPA	ENSG00000143776	0.43347309609794393	[64]	[264]	4	hSpCas9	negative selection	12331789
227034749	227034772	1	-	28162770	OCIAML3	viability	GAAAGGGTGGCAGAGAGCACTGG	CDC42BPA	ENSG00000143776	0.09188376924777375	[68]	[221]	0	hSpCas9	negative selection	12331790
227028710	227028733	1	-	28162770	OCIAML3	viability	GGGATATACACTGACTGCCAGGG	CDC42BPA	ENSG00000143776	-2.117569596381176	[22]	[15]	-8	hSpCas9	negative selection	12331791
227254063	227254086	1	-	28162770	OCIAML3	viability	TGGTCGAGGAGCTTTTGGGGAGG	CDC42BPA	ENSG00000143776	-0.33684980082703864	[40]	[97]	-3	hSpCas9	negative selection	12331792
227112320	227112343	1	-	28162770	OCIAML3	viability	GCAACTGGAAAATGAATTGGAGG	CDC42BPA	ENSG00000143776	0.16412865371765317	[114]	[388]	1	hSpCas9	negative selection	12331793
227091975	227091998	1	-	28162770	OCIAML3	viability	TGTTAGTCAAAGTGAAAGGGAGG	CDC42BPA	ENSG00000143776	-2.1245223570229426	[12]	[8]	-8	hSpCas9	negative selection	12331794
227047978	227048001	1	+	28162770	OCIAML3	viability	TGTGTGAACTGAAAGTGGAGTGG	CDC42BPA	ENSG00000143776	-0.3589041672381613	[112]	[265]	-3	hSpCas9	negative selection	12331795